Monocarboxylic and dicarboxylic acids over oceans from the East China Sea to the Arctic Ocean: Roles of ocean emissions, continental input and secondary formation.

PubMed

Hu, Qihou; Xie, Zhouqing; Wang, Xinming; Kang, Hui; Zhang, Yuqing; Ding, Xiang; Zhang, Pengfei

2018-05-30

Organic acids are major components in marine organic aerosols. Many studies on the occurrence, sources and sinks of organic acids over oceans in the low and middle latitudes have been conducted. However, the understanding of relative contributions of specific sources to organic acids over oceans, especially in the high latitudes, is still inadequate. This study measured organic acids, including C 14:0 - C 32:0 saturated monocarboxylic acids (MCAs), C 16:1 , C 18:1 and C 18:2 unsaturated MCAs, and di-C 4 - di-C 10 dicarboxylic acids (DCAs), in the marine boundary layer from the East China Sea to the Arctic Ocean during the 3rd Chinese Arctic Research Expedition (CHINARE 08). The average concentrations were 18 ± 16 ng/m 3 and 11 ± 5.4 ng/m 3 for ΣMCA and ΣDCA, respectively. The levels of saturated MCAs were much higher than those of unsaturated DCAs, with peaks at C 16:0 , C 18:0 and C 14:0 . DCAs peaked at di-C 4 , followed by di-C 9 and di-C 8 . Concentrations of MCAs and DCAs generally decreased with increasing latitudes. Sources of MCAs and DCAs were further investigated using principal component analysis with a multiple linear regression (PCA-MLR) model. Overall, carboxylic acids originated from ocean emissions, continental input (including biomass burning, anthropogenic emissions and terrestrial plant emissions), and secondary formation. All the five sources contributed to MCAs with ocean emissions as the predominant source (48%), followed by biomass burning (20%). In contrast, only 3 sources (i.e., secondary formation (50%), anthropogenic emissions (41%) and biomass burning (9%)) contributed to DCAs. Furthermore, the sources varied with regions. Over the Arctic Ocean, only secondary formation and anthropogenic emissions contributed to MCAs and DCAs. Copyright © 2018 Elsevier B.V. All rights reserved.

Faith-based HIV prevention and counseling programs: findings from the Cincinnati census of religious congregations.

PubMed

Szaflarski, Magdalena; Ritchey, P Neal; Jacobson, C Jeffrey; Williams, Rhys H; Baumann Grau, Amy; Meganathan, Karthikeyan; Ellison, Christopher G; Tsevat, Joel

2013-06-01

Congregations are well positioned to address HIV in their communities, but their response to HIV has been mixed. An emerging literature describes HIV programming in urban, predominantly black congregations, but population-based data remain limited. This study examined the levels of HIV prevention and counseling programs and associated factors (e.g., religious, organizational) by using data from a phone census of congregations in the Greater Cincinnati area (N = 447). Over 10 % of congregations (36 % of Black Protestant and 5-18 % of other types of congregations) offered HIV education/prevention alone or in combination with counseling or with counseling and testing. Path analysis results showed notable significant (p < 0.05) total effects of theology-polity on HIV prevention/counseling programs, but these effects were fully mediated by other factors, including other community work and racial composition. The levels of HIV programming in this study were high by national standards, but further outreach is needed in high-risk African American communities.

Faith-Based HIV Prevention and Counseling Programs: Findings from the Cincinnati Census of Religious Congregations

PubMed Central

Ritchey, P. Neal; Jacobson, C. Jeffrey; Williams, Rhys H.; Grau, Amy Baumann; Meganathan, Karthikeyan; Ellison, Christopher G.; Tsevat, Joel

2013-01-01

Congregations are well positioned to address HIV in their communities, but their response to HIV has been mixed. An emerging literature describes HIV programming in urban, predominantly black congregations, but population-based data remain limited. This study examined the levels of HIV prevention and counseling programs and associated factors (e.g., religious, organizational) by using data from a phone census of congregations in the Greater Cincinnati area (N = 447). Over 10 % of congregations (36 % of Black Protestant and 5–18 % of other types of congregations) offered HIV education/prevention alone or in combination with counseling or with counseling and testing. Path analysis results showed notable significant (p < 0.05) total effects of theology-polity on HIV prevention/counseling programs, but these effects were fully mediated by other factors, including other community work and racial composition. The levels of HIV programming in this study were high by national standards, but further outreach is needed in high-risk African American communities. PMID:23568226

24 CFR 982.609 - Congregate housing: Housing quality standards.

Code of Federal Regulations, 2010 CFR

2010-04-01

... URBAN DEVELOPMENT SECTION 8 TENANT BASED ASSISTANCE: HOUSING CHOICE VOUCHER PROGRAM Special Housing... apply in place of § 982.401(c) (food preparation and refuse disposal). Congregate housing is not subject... area. (b) Food preparation and refuse disposal: Additional performance requirements. The following...

7 CFR 3560.69 - Supplemental requirements for congregate housing and group homes.

Code of Federal Regulations, 2010 CFR

2010-01-01

...; (iii) Assistance in housekeeping; (iv) Personal services; (v) Recreational and social activities; and... prepare meals; (ii) Transportation; (iii) Nearby recreational and social activities which may be... areas are made available to congregate housing or group homes. The 2 percent initial operating capital...

7 CFR 3560.69 - Supplemental requirements for congregate housing and group homes.

Code of Federal Regulations, 2011 CFR

2011-01-01

...; (iii) Assistance in housekeeping; (iv) Personal services; (v) Recreational and social activities; and... prepare meals; (ii) Transportation; (iii) Nearby recreational and social activities which may be... areas are made available to congregate housing or group homes. The 2 percent initial operating capital...

24 CFR 982.608 - Congregate housing: Voucher housing assistance payment.

Code of Federal Regulations, 2011 CFR

2011-04-01

... HOUSING AND URBAN DEVELOPMENT SECTION 8 TENANT BASED ASSISTANCE: HOUSING CHOICE VOUCHER PROGRAM Special... the zero-bedroom payment standard amount on the PHA payment standard schedule. For a family residing in congregate housing in an exception area, the payment standard is the HUD-approved zero-bedroom...

40 CFR 63.1215 - What are the health-based compliance alternatives for total chlorine?

Code of Federal Regulations, 2014 CFR

2014-07-01

... congregate for work, school, or recreation. (iii) Your facility is eligible for the health-based compliance... for work, school, or recreation; (C) Use site-specific, quality-assured data wherever possible; (D... population data, including areas where people congregate for work, school, or recreation; and (4) Other...

40 CFR 63.1215 - What are the health-based compliance alternatives for total chlorine?

Code of Federal Regulations, 2013 CFR

2013-07-01

... congregate for work, school, or recreation. (iii) Your facility is eligible for the health-based compliance... for work, school, or recreation; (C) Use site-specific, quality-assured data wherever possible; (D... population data, including areas where people congregate for work, school, or recreation; and (4) Other...

24 CFR 982.608 - Congregate housing: Voucher housing assistance payment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... the zero-bedroom payment standard amount on the PHA payment standard schedule. For a family residing in congregate housing in an exception area, the payment standard is the HUD-approved zero-bedroom... one-bedroom payment standard amount. (b) If there is a live-in aide, the live-in aide must be counted...

Congregate retirement communities: exploring the importance of services and activities as viewed by residents, potential residents, and administrators.

PubMed

Cangelosi, J D; McAlhany, J W

1989-03-01

Given the demographic trends, which indicate a need for facilities to accommodate a rapidly increasing and healthier elderly population, our study provides relevant and timely information for builders and health care administrators who are considering the initial construction of or addition to a congregate retirement facility. Though a congregate retirement facility must satisfy the demands of its residents for services and activities, cost considerations make it equally important for builders and administrators to offer only those services that are essential to meet those demands successfully. A multitude of services and activities may seem attractive to the general population and to investors as they formulate plans for new congregate facilities, but there is little need to provide or fund services and activities that are not used or demanded. Our findings show that the elderly target market for congregate facilities is primarily concerned with "necessity" services such as transportation, shopping, security, health care, and appearance, rather than the availability of a multitude of nonessential recreational and cultural activities. In summary, congregate facilities currently offer numerous activities and services that are not being used and are not important to residents or potential residents. Our exploratory research examines an area that has not been studied extensively and the findings are important in planning for the future. By using these findings, administrators and planners of congregate facilities should be able to determine effectively the types of services and activities that will satisfy the demands of the elderly during their retirement.

Gene repression via multiplex gRNA strategy in Y. lipolytica.

PubMed

Zhang, Jin-Lai; Peng, Yang-Zi; Liu, Duo; Liu, Hong; Cao, Ying-Xiu; Li, Bing-Zhi; Li, Chun; Yuan, Ying-Jin

2018-04-20

The oleaginous yeast Yarrowia lipolytica is a promising microbial cell factory due to their biochemical characteristics and native capacity to accumulate lipid-based chemicals. To create heterogenous biosynthesis pathway and manipulate metabolic flux in Y. lipolytica, numerous studies have been done for developing synthetic biology tools for gene regulation. CRISPR interference (CRISPRi), as an emerging technology, has been applied for specifically repressing genes of interest. In this study, we established CRISPRi systems in Y. lipolytica based on four different repressors, that was DNase-deactivated Cpf1 (dCpf1) from Francisella novicida, deactivated Cas9 (dCas9) from Streptococcus pyogenes, and two fusion proteins (dCpf1-KRAB and dCas9-KRAB). Ten gRNAs that bound to different regions of gfp gene were designed and the results indicated that there was no clear correlation between the repression efficiency and targeting sites no matter which repressor protein was used. In order to rapidly yield strong gene repression, a multiplex gRNAs strategy based on one-step Golden-brick assembly technology was developed. High repression efficiency 85% (dCpf1) and 92% (dCas9) were achieved in a short time by making three different gRNAs towards gfp gene simultaneously, which avoided the need of screening effective gRNA loci in advance. Moreover, two genes interference including gfp and vioE and three genes repression including vioA, vioB and vioE in protodeoxy-violaceinic acid pathway were also realized. Taken together, successful CRISPRi-mediated regulation of gene expression via four different repressors dCpf1, dCas9, dCpf1-KRAB and dCas9-KRAB in Y. lipolytica is achieved. And we demonstrate a multiplexed gRNA targeting strategy can efficiently achieve transcriptional simultaneous repression of several targeted genes and different sites of one gene using the one-step Golden-brick assembly. This timesaving method promised to be a potent transformative tool valuable for metabolic engineering, synthetic biology, and functional genomic studies of Y. lipolytica.

Seasonal Variations of Quantified Organic Compounds in PM10 over Seoul

NASA Astrophysics Data System (ADS)

Choi, N.; Lee, J.; Kim, Y. P.

2014-12-01

The concentrations of 87 individual organic matters in the PM10 samples, systematically collected on the roof of the School of Public Health building at Seoul National University (mixed commercial and residential area), Seoul, South Korea on a daily basis from April 2010 to April 2011, were quantified by mean of Gas Chromatography/Mass Spectrometry (GC/MS). The daily average concentrations of five organic groups, alkanes, PAHs, fatty acid, DCAs, and sugars were ranged from 498.40 ng m3 to 10.20 μg m3. The seasonal concentrations of the total quantified organic species were 1.73 μg m3 (Spring), 2.04 μg m3 (Summer), 3.11 μg m3 (Fall), and 3.60 μg m3 (Winter), respectively. All the organic groups showed higher average concentration in winter than in summer. However, some organic compounds among fatty acids, DCAs, and sugars showed reverse pattern. The seasonal concentration patterns and episode variation of individual organic compounds were studied to clarify the emission characteristics of organic matters in PM10.

Inducible CRISPR genome-editing tool: classifications and future trends.

PubMed

Dai, Xiaofeng; Chen, Xiao; Fang, Qiuwu; Li, Jia; Bai, Zhonghu

2018-06-01

The discovery of CRISPR-Cas9/dCas9 system has reinforced our ability and revolutionized our history in genome engineering. While Cas9 and dCas9 are programed to modulate gene expression by introducing DNA breaks, blocking transcription factor recruitment or dragging functional groups towards the targeted sites, sgRNAs determine the genomic loci where the modulation occurs. The off-target problem, due to limited sgRNA specificity and genome complexity of many species, has posed concerns for the wide application of this revolutionary technique. To solve this problem and, more importantly, gain power over gene functionality and cell fate control, inducible strategies have been continuously evolved to offer tailored solutions to address specific biological questions. By reviewing recent advances in inducible CRISPR system design and critical elements potentially adding values to such systems, we classify current approaches in this domain into four mechanically distinct categories, namely, "split system", "allosteric system", "combinatorial system", and "transient delivery system", discuss the pros and cons of each system, and point out the under-explored areas and future directions, with the aim of enriching our toolbox of delicate life engineering.

CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells.

PubMed

Deng, Wulan; Shi, Xinghua; Tjian, Robert; Lionnet, Timothée; Singer, Robert H

2015-09-22

Direct visualization of genomic loci in the 3D nucleus is important for understanding the spatial organization of the genome and its association with gene expression. Various DNA FISH methods have been developed in the past decades, all involving denaturing dsDNA and hybridizing fluorescent nucleic acid probes. Here we report a novel approach that uses in vitro constituted nuclease-deficient clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated caspase 9 (Cas9) complexes as probes to label sequence-specific genomic loci fluorescently without global DNA denaturation (Cas9-mediated fluorescence in situ hybridization, CASFISH). Using fluorescently labeled nuclease-deficient Cas9 (dCas9) protein assembled with various single-guide RNA (sgRNA), we demonstrated rapid and robust labeling of repetitive DNA elements in pericentromere, centromere, G-rich telomere, and coding gene loci. Assembling dCas9 with an array of sgRNAs tiling arbitrary target loci, we were able to visualize nonrepetitive genomic sequences. The dCas9/sgRNA binary complex is stable and binds its target DNA with high affinity, allowing sequential or simultaneous probing of multiple targets. CASFISH assays using differently colored dCas9/sgRNA complexes allow multicolor labeling of target loci in cells. In addition, the CASFISH assay is remarkably rapid under optimal conditions and is applicable for detection in primary tissue sections. This rapid, robust, less disruptive, and cost-effective technology adds a valuable tool for basic research and genetic diagnosis.

Honeybee drones are attracted by groups of consexuals in a walking simulator.

PubMed

Brandstaetter, Andreas Simon; Bastin, Florian; Sandoz, Jean-Christophe

2014-04-15

During the mating season, honeybee males, the drones, gather in congregation areas 10-40 m above ground. When a receptive female, a queen, enters the congregation, drones are attracted to her by queen-produced pheromones and visual cues and attempt to mate with the queen in mid-air. It is still unclear how drones and queens find the congregations. Visual cues on the horizon are most probably used for long-range orientation. For shorter-range orientation, however, attraction by a drone-produced aggregation pheromone has been proposed, yet so far its existence has not been confirmed conclusively. The low accessibility of congregation areas high up in the air is a major hurdle and precise control of experimental conditions often remains unsatisfactory in field studies. Here, we used a locomotion compensator-based walking simulator to investigate drones' innate odor preferences under controlled laboratory conditions. We tested behavioral responses of drones to 9-oxo-2-decenoic acid (9-ODA), the major queen-produced sexual attractant, and to queen mandibular pheromone (QMP), an artificial blend of 9-ODA and several other queen-derived components. While 9-ODA strongly dominates the odor bouquet of virgin queens, QMP rather resembles the bouquet of mated queens. In our assay, drones were attracted by 9-ODA, but not by QMP. We also investigated the potential attractiveness of male-derived odors by testing drones' orientation responses to the odor bouquet of groups of 10 living drones or workers. Our results demonstrate that honeybee drones are attracted by groups of other drones (but not by workers), which may indicate a role of drone-emitted cues for the formation of congregations.

United by Faith? Race/Ethnicity, Congregational Diversity, and Explanations of Racial Inequality

PubMed Central

Cobb, Ryon J.; Perry, Samuel L.; Dougherty, Kevin D.

2016-01-01

This study examines the extent to which the racial composition of a congregation moderates explanations for Black/White inequality among White, Black, and Hispanic congregants. Using nationally representative data from General Social Surveys and National Congregations Studies, we find that religiously affiliated Blacks and Hispanics tend to hold different racial attitudes than religiously affiliated Whites, but these differences largely disappear inside multiracial congregations. Importantly, we find that attending a multiracial congregation is unassociated with Whites’ explanations for racial inequality, and Blacks who attend multiracial congregations are actually less likely to affirm structural explanations for Black/White inequality than Blacks in nonmultiracial congregations or Whites in multiracial congregations. We find little evidence that multiracial congregations promote progressive racial views among attendees of any race or ethnicity. Rather, our findings suggest that multiracial congregations (1) leave dominant White racial frames unchallenged, potentially influencing minority attendees to embrace such frames and/or (2) attract racial minorities who are more likely to embrace those frames in the first place. PMID:27429542

Social entrepreneurship in religious congregations' efforts to address health needs.

PubMed

Werber, Laura; Mendel, Peter J; Derose, Kathryn Pitkin

2014-01-01

Examine how religious congregations engage in social entrepreneurship as they strive to meet health-related needs in their communities. Multiple case studies. Los Angeles County, California. Purposive sample of 14 congregations representing diverse races/ethnicities (African-American, Latino, and white) and faith traditions (Jewish and various Christian). Congregations were recruited based on screening data and consultation of a community advisory board. In each congregation, researchers conducted interviews with clergy and lay leaders (n = 57); administered a congregational questionnaire; observed health activities, worship services, and neighborhood context; and reviewed archival information. Interviews were analyzed by using a qualitative, code-based approach. Congregations' health-related activities tended to be episodic, small in scale, and local in scope. Trust and social capital played important roles in congregations' health initiatives, providing a safe, confidential environment and leveraging resources from-and for-faith-based and secular organizations in their community networks. Congregations also served as "incubators" for members to engage in social entrepreneurship. Although the small scale of congregations' health initiatives suggest they may not have the capacity to provide the main infrastructure for service provision, congregations can complement the efforts of health and social providers with their unique strengths. Specifically, congregations are distinctive in their ability to identify unmet local needs, and congregations' position in their communities permit them to network in productive ways.

Program prioritization to control chronic diseases in African-American faith-based communities.

PubMed

Hoyo, Cathrine; Reid, Laverne; Hatch, John; Sellers, Denethia B; Ellison, Arlinda; Hackney, Tara; Porterfield, Deborah; Page, Joyce; Parrish, Theodore

2004-04-01

In the last decade, African-American congregations have been inundated with requests to participate in health promotion activities; however, most are not equipped to effectively participate. We assessed the effect of providing congregation leaders with skills on identifying their own health needs, planning, and implementing their own interventions. At baseline, 21 congregational leaders from South East Raleigh, NC were taught methods for developing needs assessments, planning, and implementing health promotion activities tailored for their congregations. After approximately four years, 14 of the 21 congregations were successfully recontacted. At baseline, the congregation leadership ranked diabetes as the ninth (out of 10) most urgent health concern in their communities. However, at follow-up, not only was diabetes identified as the most serious health concern, but most congregations had taken advantage of available community and congregational resources to prevent it. Larger congregations were more likely than smaller ones to take advantage of available resources. Larger African-American congregations are an effective vehicle by which health promotion messages can diffuse; however, the leadership must be provided with skills to assess health needs before selecting programs most beneficial to their congregations. Mechanisms by which small congregation leaders can participate need development.

Program prioritization to control chronic diseases in African-American faith-based communities.

PubMed Central

Hoyo, Cathrine; Reid, Laverne; Hatch, John; Sellers, Denethia B.; Ellison, Arlinda; Hackney, Tara; Porterfield, Deborah; Page, Joyce; Parrish, Theodore

2004-01-01

OBJECTIVE: In the last decade, African-American congregations have been inundated with requests to participate in health promotion activities; however, most are not equipped to effectively participate. We assessed the effect of providing congregation leaders with skills on identifying their own health needs, planning, and implementing their own interventions. METHODS: At baseline, 21 congregational leaders from South East Raleigh, NC were taught methods for developing needs assessments, planning, and implementing health promotion activities tailored for their congregations. After approximately four years, 14 of the 21 congregations were successfully recontacted. RESULTS: At baseline, the congregation leadership ranked diabetes as the ninth (out of 10) most urgent health concern in their communities. However, at follow-up, not only was diabetes identified as the most serious health concern, but most congregations had taken advantage of available community and congregational resources to prevent it. Larger congregations were more likely than smaller ones to take advantage of available resources. CONCLUSIONS: Larger African-American congregations are an effective vehicle by which health promotion messages can diffuse; however, the leadership must be provided with skills to assess health needs before selecting programs most beneficial to their congregations. Mechanisms by which small congregation leaders can participate need development. PMID:15101672

24 CFR 982.607 - Congregate housing: Lease and HAP contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Congregate housing: Lease and HAP... Types Congregate Housing § 982.607 Congregate housing: Lease and HAP contract. For congregate housing, there is a separate lease and HAP contract for each assisted family. ...

24 CFR 982.606 - Congregate housing: Who may reside in congregate housing.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT SECTION 8 TENANT BASED ASSISTANCE: HOUSING CHOICE VOUCHER PROGRAM Special Housing Types Congregate Housing § 982.606 Congregate housing: Who may reside in congregate...

Religious congregations as mediating structures for social justice: a multilevel examination.

PubMed

Todd, Nathan R; Allen, Nicole E

2011-12-01

Scholars in the field of community psychology have called for a closer examination of the mediating role that religious congregations serve in society, especially in relation to the promotion of social justice. The current study provides such an examination, offering a multilevel examination of religious individuals (n = 5,123) nested within religious congregations (n = 62) with a particular focus on how individual and congregational level variables (i.e. theological orientation, frequency of religious attendance, bonding and bridging social capital) predict individual prioritization of and participation in congregational social justice activities. Findings indicated that individual level theological orientation was associated with prioritization, and demographics and social capital bonding were associated with prioritization and participation. Furthermore, congregational bridging social capital was associated with the prioritization of justice, whereas congregational theological orientation moderated the associations between frequency of religious participation for both prioritization of and participation in congregational justice activities. These findings show that specific aspects of the congregational setting (i.e., congregational theological orientation) are important to the individual prioritization of and participation in social justice activities. These findings provide support for the role of religious congregations as mediating structures for social justice. Implications for future research are also discussed.

Photooxidation of dicarboxylic acids—Part I: Effects of inorganic ions on degradation of azelaic acid

NASA Astrophysics Data System (ADS)

Yang, Liming; Ray, Madhumita B.; Yu, Liya E.

In this paper, the first of a two-part series, effects of chloride, sulfate, and nitrate ions and pH on photooxidation of azelaic acid were investigated in an aqueous system. Nitrate ions play the major role in accelerating photooxidation of azelaic acid by increasing rad OH concentration, while chloride ions consume rad OH concentration and retard photooxidation rates. In inorganic mixtures, a nitrate-to-chloride molar ratio of >1.5 accelerated photooxidation of azelaic acid indicating the dominant role of nitrate. Substantial inhibition effects of chloride on photooxidation of azelaic acid were demonstrated at a nitrate-to-chloride molar ratio <0.3. Nitrate and chloride are interrelated in affecting photooxidation of azelaic acid as photolysis of nitrate would significantly consume H +, retarding reaction of HOCl - with H +, and consequently decreasing rad OH-chloride reaction. pH affects photooxidation of C 2-C 9 dicarboxylic acids (DCAs) in two ways: C 2-C 4 dicarboxylates exhibit substantially higher degradation rates than their parent DCAs, while C 5-C 9 dicarboxylates demonstrate degradation rates similar to their parent DCAs.

Information Culture and Belief Formation in Religious Congregations

ERIC Educational Resources Information Center

Freeburg, Darin

2013-01-01

This qualitative study investigated the information culture and beliefs within two United Church of Christ congregations in Northeast Ohio. One congregation was Open and Affirming (ONA), and one congregation was not. ONA refers to a congregation's decision to be listed as a place where LGBT individuals--in particular--are welcomed and accepted.…

Prevalence and Predictors of Mental Health Programming Among U.S. Religious Congregations.

PubMed

Wong, Eunice C; Fulton, Brad R; Derose, Kathryn P

2018-02-01

This study assessed the prevalence of and factors associated with congregation-based programming in support of people with mental illness. To estimate the proportion of congregations that provide mental health programming, this study reports analyses of survey responses from the 2012 National Congregations Study, a nationally representative survey of religious congregations in the United States (N=1,327). The analysis used multivariate logistic regression to identify congregational characteristics associated with the provision of mental health programming. Nearly one in four U.S. congregations (23%) provided some type of programming to support people with mental illness. Approximately 31% of all attendees belonged to a congregation that provided mental health programming. Congregational characteristics associated with providing mental health programming included having more members and having members with higher incomes, employing staff for social service programs, and providing health-focused programs. Other significant predictors included engaging with the surrounding community (that is, conducting community needs assessments and hosting speakers from social service organizations) and being located in a predominantly African-American community. Greater coordination between mental health providers and congregations with programs that support people with mental illness could foster more integrated and holistic care, which in turn may lead to improved recovery outcomes.

Genome-scale model-driven strain design for dicarboxylic acid production in Yarrowia lipolytica.

PubMed

Mishra, Pranjul; Lee, Na-Rae; Lakshmanan, Meiyappan; Kim, Minsuk; Kim, Byung-Gee; Lee, Dong-Yup

2018-03-19

Recently, there have been several attempts to produce long-chain dicarboxylic acids (DCAs) in various microbial hosts. Of these, Yarrowia lipolytica has great potential due to its oleaginous characteristics and unique ability to utilize hydrophobic substrates. However, Y. lipolytica should be further engineered to make it more competitive: the current approaches are mostly intuitive and cumbersome, thus limiting its industrial application. In this study, we proposed model-guided metabolic engineering strategies for enhanced production of DCAs in Y. lipolytica. At the outset, we reconstructed genome-scale metabolic model (GSMM) of Y. lipolytica (iYLI647) by substantially expanding the previous models. Subsequently, the model was validated using three sets of published culture experiment data. It was finally exploited to identify genetic engineering targets for overexpression, knockout, and cofactor modification by applying several in silico strain design methods, which potentially give rise to high yield production of the industrially relevant long-chain DCAs, e.g., dodecanedioic acid (DDDA). The resultant targets include (1) malate dehydrogenase and malic enzyme genes and (2) glutamate dehydrogenase gene, in silico overexpression of which generated additional NADPH required for fatty acid synthesis, leading to the increased DDDA fluxes by 48% and 22% higher, respectively, compared to wild-type. We further investigated the effect of supplying branched-chain amino acids on the acetyl-CoA turn-over rate which is key metabolite for fatty acid synthesis, suggesting their significance for production of DDDA in Y. lipolytica. In silico model-based strain design strategies allowed us to identify several metabolic engineering targets for overproducing DCAs in lipid accumulating yeast, Y. lipolytica. Thus, the current study can provide a methodological framework that is applicable to other oleaginous yeasts for value-added biochemical production.

Engineering Escherichia coli for Conversion of Glucose to Medium-Chain ω-Hydroxy Fatty Acids and α,ω-Dicarboxylic Acids.

PubMed

Bowen, Christopher H; Bonin, Jeff; Kogler, Anna; Barba-Ostria, Carlos; Zhang, Fuzhong

2016-03-18

In search of sustainable approaches to plastics production, many efforts have been made to engineer microbial conversions of renewable feedstock to short-chain (C2-C8) bifunctional polymer precursors (e.g., succinic acid, cadaverine, 1,4-butanediol). Less attention has been given to medium-chain (C12-C14) monomers such as ω-hydroxy fatty acids (ω-OHFAs) and α,ω-dicarboxylic acids (α,ω-DCAs), which are precursors to high performance polyesters and polyamides. Here we engineer a complete microbial conversion of glucose to C12 and C14 ω-OHFAs and α,ω-DCAs, with precise control of product chain length. Using an expanded bioinformatics approach, we screen a wide range of enzymes across phyla to identify combinations that yield complete conversion of intermediates to product α,ω-DCAs. Finally, through optimization of culture conditions, we enhance production titer of C12 α,ω-DCA to nearly 600 mg/L. Our results indicate potential for this microbial factory to enable commercially relevant, renewable production of C12 α,ω-DCA-a valuable precursor to the high-performance plastic, nylon-6,12.

Religious Congregations’ HIV and Other Health Collaborations: With Whom Do They Work And What Do They Share?

PubMed Central

Werber, Laura; Derose, Kathryn Pitkin; Dominguez, Blanca X.; Mata, Michael A.

2012-01-01

This study explores how religious congregations interact with other community organizations to address health and, in particular, HIV-related needs within their membership and/or local communities. Case study data from a diverse sample of 14 urban congregations (6 African American, 4 Latino, 2 Anglo and 2 mixed race-ethnicity) indicate they engaged in three types of relationships to conduct HIV and other health-related activities, i.e. those where: 1) resources flowed to congregations from external entities; 2) resources flowed from congregations to external entities; 3) congregations interacted with external entities. These types of relationships were present in roughly equal proportions; thus, congregations were not primarily the recipients of resources from other organizations in these interactions. Financial, material, and human capital resources were shared across these three relationship types, and the most common organization types that congregations were involved with for health efforts were prevention and social service organizations, health care providers, and other congregations. In addition, congregations tended to have more collaborative relationships with other FBOs and to engage with non-FBOs more to either receive or provide resources. Results suggest that congregations contribute to community health by not only sponsoring health activities for their own members but also by providing specific support or resources to enhance the programming of other community organizations and collaborating with external organizations to sponsor congregation-based and community-based health activities. PMID:22491006

Diagnostic grouping among adults with intellectual disabilities and autistic spectrum disorders in staffed housing.

PubMed

Felce, D; Perry, J

2012-12-01

There is little evidence to guide the commissioning of residential provision for adults with autistic spectrum disorder (ASD) in the UK. We aim to explore the degree and impact of diagnostic congregation among adults with intellectual disabilities (ID) and ASD living in staffed housing. One hundred and fifty-seven adults with intellectual disabilities from a sample of 424 in staffed housing were assessed as having the triad of impairments characteristic of ASD. They lived in 88 houses: 26 were non-congregate (40% or fewer residents had the triad) and 50 congregate (60% or more had the triad); 12 with intermediate groupings were eliminated. Non-congregate and congregate groups were compared on age, gender, adaptive and challenging behaviour, house size, staff per resident and various measures of quality of care and quality of outcome. Comparisons were repeated for Adaptive Behavior Scale (ABS)-matched, congregate and non-congregate subsamples. Non-congregate settings were larger, had lower staff per resident and more individualised social milieus. Groups were similar in age and gender but the non-congregate group had non-significantly higher ABS scores. The non-congregate group did more social, community and household activities. After matching for ABS, these outcome differences ceased to be significant. Non-congregate settings were significantly larger and had significantly more organised working methods. The findings are consistent with other research that finds few advantages to diagnostic grouping. © 2011 The Authors. Journal of Intellectual Disability Research © 2011 Blackwell Publishing Ltd.

Thinkers and feelers: Emotion and giving.

PubMed

Corcoran, Katie E

2015-07-01

Voluntary organizations, such as religious congregations, ask their members to contribute money as a part of membership and rely on these contributions for their survival. Yet often only a small cadre of members provides the majority of the contributions. Past research on congregational giving focuses on cognitive rational processes, generally neglecting the role of emotion. Extending Collins' (2004) interaction ritual theory, I predict that individuals who experience positive emotions during religious services will be more likely to give a higher proportion of their income to their congregation than those who do not. Moreover, I argue that this effect will be amplified in congregational contexts characterized by high aggregate levels of positive emotion, strictness, dense congregational networks, and expressive rituals. Using data from the 2001 U.S. Congregational Life Survey and multilevel modeling, I find support for several of these hypotheses. The findings suggest that both cognitive and emotional processes underlie congregational giving. Copyright © 2014 Elsevier Inc. All rights reserved.

The response of religious congregations to the spiritual needs of people living with HIV/AIDS.

PubMed

Somlai, A M; Heckman, T G; Kelly, J A; Mulry, G W; Multhauf, K E

1997-01-01

Investigates the perceptions and responses of members of five diverse religious congregations to the spiritual needs of people living with AIDS, the impact of AIDS on membership participation, and the beliefs held by different congregations regarding AIDS. Evaluates and compares the AIDS-related perceptions of 204 participants in five congregations (Buddhists, Catholic, Fundamental Christians, Protestants, and Unitarians). Results indicated that congregations differed in how their members responded to the spiritual needs of people living with HIV/AIDS, the level of influence AIDS had on membership participation in formal religions, and whether AIDS was seen as the result of sinful behavior or divine retribution. Concludes that the congregational differences appeared consistent with the core beliefs of the faith communities. Suggests that clergy and congregations need to take specific steps to provide spiritual support to people living with HIV/AIDS consistent with their history of caregiving to all people regardless of the crisis situation.

An inducible CRISPR-ON system for controllable gene activation in human pluripotent stem cells.

PubMed

Guo, Jianying; Ma, Dacheng; Huang, Rujin; Ming, Jia; Ye, Min; Kee, Kehkooi; Xie, Zhen; Na, Jie

2017-05-01

Human pluripotent stem cells (hPSCs) are an important system to study early human development, model human diseases, and develop cell replacement therapies. However, genetic manipulation of hPSCs is challenging and a method to simultaneously activate multiple genomic sites in a controllable manner is sorely needed. Here, we constructed a CRISPR-ON system to efficiently upregulate endogenous genes in hPSCs. A doxycycline (Dox) inducible dCas9-VP64-p65-Rta (dCas9-VPR) transcription activator and a reverse Tet transactivator (rtTA) expression cassette were knocked into the two alleles of the AAVS1 locus to generate an iVPR hESC line. We showed that the dCas9-VPR level could be precisely and reversibly controlled by the addition and withdrawal of Dox. Upon transfection of multiplexed gRNA plasmid targeting the NANOG promoter and Dox induction, we were able to control NANOG gene expression from its endogenous locus. Interestingly, an elevated NANOG level promoted naïve pluripotent gene expression, enhanced cell survival and clonogenicity, and enabled hESCs to integrate with the inner cell mass (ICM) of mouse blastocysts in vitro. Thus, iVPR cells provide a convenient platform for gene function studies as well as high-throughput screens in hPSCs.

Quantification of Emphysema: A Bullae Distribution Based Approach

NASA Astrophysics Data System (ADS)

Tan, Kok Liang; Tanaka, Toshiyuki; Nakamura, Hidetoshi; Shirahata, Toru; Sugiura, Hiroaki

Computed tomography (CT)-based quantifications of emphysema encompass, and are not limited to, the ratio of the low-attenuation area, the bullae size, and the distribution of bullae in the lung. The standard CT-based emphysema describing indices include the mean lung density, the percentage of area of low attenuation [the pixel index (PI)] and the bullae index (BI). These standard emphysema describing indices are not expressive for describing the distribution of bullae in the lung. Consequently, the goal of this paper is to present a new emphysema describing index, the bullae congregation index (BCI), that describes whether bullae gather in a specific area of the lung and form a nearly single mass, and if so, how dense the mass of bullae is in the lung. BCI ranges from zero to ten corresponding to sparsely distributed bullae to densely distributed bullae. BCI is calculated based on the relative distance between every pair of bullae in the lung. The bullae pair distances are sorted into 200 distance classes. A smaller distance class corresponds to a closer proximity between the bullae. BCI is derived by calculating the percentage of the area of bullae in the lung that are separated by a certain distance class. Four bullae congregation classes are defined based on BCI. We evaluate BCI using 114 CT images that are hand-annotated by a radiologist into four bullae congregation classes. The average four-class classification accuracy of BCI is 88.21%. BCI correlates better than PI, BI and other standard statistical dispersion based methods with the radiological consensus-classified bullae congregation class.While BCI is not a specific index for indicating emphysema severity, it complements the existing set of emphysema describing indices to facilitate a more thorough knowledge about the emphysematous conditions in the lung. BCI is especially useful when it comes to comparing the distribution of bullae for cases with approximately the same PI, BI or PI and BI. BCI is easy to interpret and potentitally helpful for the purpose of comparative study and progressive monitoring of emphysema.

US Religious Congregations' Programming to Support Veterans: A Mixed Methods Study.

PubMed

Derose, Kathryn Pitkin; Haas, Ann; Werber, Laura

2016-06-01

Religious congregations may be well equipped to address veterans' reintegration needs, but little is known about the prevalence and nature of such support. We conducted a mixed methods study using nationally representative congregational survey data and in-depth interviews with congregational leaders. Overall, 28% of congregations nationally reported having programming to support veterans and positive, independent predictors included: community context (county veteran presence, high-poverty census tract, rural compared to urban location); congregational resources (more adult attendees, having a paid employee that spent time on service programs); and external engagement (assessing community needs, collaboration, and social service participation). Qualitative interviews revealed a range of activities, including attending to spiritual issues, supporting mental, physical and social well-being, and addressing vocational, legal, financial, and material needs.

Relationships between breeding status, social -congregation attendance, and foraging distance of xantus's murrelets

USGS Publications Warehouse

Hamilton, C.D.; Golightly, R.T.; Takekawa, John Y.

2011-01-01

At night during the breeding season, Xantus's Murrelets (Synthliboramphus hypoleucus) congregate on the water adjacent to nesting colonies. We examined relationships of attendance at these nocturnal congregations, breeding status, and daytime foraging locations of radio-marked Xantus's Murrelets from Anacapa Island (33 in 2002, 44 in 2003) and Santa Barbara Island (35 in 2002) in the California Channel Islands. Murrelets thatspent more nights attending congregations were located closer to the island during the day, so regular attendance at the congregations may have constrained daytime traveling distances to foraging locations. In mid-May 2003 home-range sizes increased while congregation attendance decreased, likely indicating the end of colony attendance and declining availability of prey near Anacapa Island. In both years, incubating murrelets foraged farther from the colony than did nonbreeding murrelets, suggesting that breeding and nonbreeding murrelets use different foraging strategies to meet their energetic requirements. Copyright ?? The Cooper Ornithological Society 2011.

Seasonal variation of organic aerosol in PM2.5 at Anmyeondo, a background site in Korea

NASA Astrophysics Data System (ADS)

Lee, J.; Kim, E. S.; Kim, Y. P.; Jung, C. H.; Lee, J.

2016-12-01

Routine measurements of PM2.5 and chemical speciation for 100 individual organic compounds were carried out to understand seasonal variation of organic compounds at a background area in Korea between 2015 and 2016. Organic compounds analyzed in this study were classified into five groups, n-alkanes, polycyclic aromatic hydrocarbons (PAHs), fatty acids (FA), dicarboxylic acids (DCAs), and sugar. Further, organic carbon (OC), elemental carbon (EC), water-soluble organic carbon (WSOC) and Humic Like Substance-Carbon (HULIS-C) in PM2.5 were simultaneously analyzed to make mass balance of carbonaceous aerosol in PM2.5 at a background site in Korea. PAHs concentrations at this site was lower than that at Seoul, a representative urban site in Korea. PAHs and n-Alkanes concentrations showed clear seasonal variation with summer minimum and winter maximum, while, seasonal variation of DCAs and Sugars were different with PAHs and n-Alkanes.WSOC concentrations were highly correlated with SOC (Secondary Organic Carbon) concentrations which were estimated by the EC tracer method. The results indicate the formation of secondary organic aerosol (SOA) is major factor for the determination of WSOC concentrations in this region. HULIS-C as known one of brown carbon was major component of WSOC which accounts for 39 to 99% in WSOC. The average concentrations of HULIS-C was 2.02±1.42 and the highest concentration was observed in fall.

Suppression of HBV replication by the expression of nickase- and nuclease dead-Cas9.

PubMed

Kurihara, Takeshi; Fukuhara, Takasuke; Ono, Chikako; Yamamoto, Satomi; Uemura, Kentaro; Okamoto, Toru; Sugiyama, Masaya; Motooka, Daisuke; Nakamura, Shota; Ikawa, Masato; Mizokami, Masashi; Maehara, Yoshihiko; Matsuura, Yoshiharu

2017-07-21

Complete removal of hepatitis B virus (HBV) DNA from nuclei is difficult by the current therapies. Recent reports have shown that a novel genome-editing tool using Cas9 with a single-guide RNA (sgRNA) system can cleave the HBV genome in vitro and in vivo. However, induction of a double-strand break (DSB) on the targeted genome by Cas9 risks undesirable off-target cleavage on the host genome. Nickase-Cas9 cleaves a single strand of DNA, and thereby two sgRNAs are required for inducing DSBs. To avoid Cas9-induced off-target mutagenesis, we examined the effects of the expressions of nickase-Cas9 and nuclease dead Cas9 (d-Cas9) with sgRNAs on HBV replication. The expression of nickase-Cas9 with a pair of sgRNAs cleaved the target HBV genome and suppressed the viral-protein expression and HBV replication in vitro. Moreover, nickase-Cas9 with the sgRNA pair cleaved the targeted HBV genome in mouse liver. Interestingly, d-Cas9 expression with the sgRNAs also suppressed HBV replication in vitro without cleaving the HBV genome. These results suggest the possible use of nickase-Cas9 and d-Cas9 with a pair of sgRNAs for eliminating HBV DNA from the livers of chronic hepatitis B patients with low risk of undesirable off-target mutation on the host genome.

Social Entrepreneurship in Religious Congregations’ Efforts to Address Health Needs

PubMed Central

Werber, Laura; Mendel, Peter J.; Derose, Kathryn Pitkin

2013-01-01

Purpose Examine how religious congregations engage in social entrepreneurship as they strive to meet health-related needs in their communities. Design Multiple case studies. Setting Los Angeles County, California. Participants Purposive sample of 14 congregations representing diverse races-ethnicities (African American, Latino, and white) and faith traditions (Jewish and various Christian). Method Congregations were recruited based on screening data and consultation of a community advisory board. In each congregation, researchers conducted interviews with clergy and lay leaders (n=57); administered a congregational questionnaire; observed health activities, worship services, and neighborhood context; and reviewed archival information. Interviews were analyzed using a qualitative, code-based approach. Results Congregations’ health-related activities tended to be episodic, small in scale, and local in scope. Trust and social capital played important roles in congregations’ health initiatives, providing a safe, confidential environment and leveraging resources from – and for – faith-based and secular organizations in their community networks. Congregations also served as “incubators” for members to engage in social entrepreneurship. Conclusion Although the small scale of congregations’ health initiatives suggest they may not have the capacity to provide the main infrastructure for service provision, congregations can complement the efforts of health and social providers with their unique strengths. Specifically, congregations are distinctive in their ability to identify unmet local needs, and congregations’ position in their communities permit them to network in productive ways. PMID:23875986

30 CFR 77.1101 - Escape and evacuation; plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... where persons are required to work or travel including buildings and equipment and in areas where persons normally congregate during the work shift. (Pub. L. No. 96-511, 94 Stat. 2812 (44 U.S.C. 3501 et... HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES...

Key Resources for Qualitative Congregational Research

ERIC Educational Resources Information Center

Ratcliff, Donald

2009-01-01

Congregational research using qualitative procedures is an important aspect of effective Religious Education, and appears to be growing in importance. In this article, the author focuses on several resources for qualitative congregational research. While many good sources will be considered, missing is a truly comprehensive source that examines…

Alternative Locales for the Health Promotion of African American Men: A Survey of African American Men in Chicago Barbershops

PubMed Central

Moore, N. J.; Wright, M.; Gipson, J.; Keeter, M.; Cornelious, T.; Reed, D.; Russell, J.; Watson, K. S.; Murray, M.

2018-01-01

African American men (AA) carry unequal burdens of several conditions including cancer, diabetes, hypertension, and HIV. Engagement of diverse populations including AA men in research and health promotion practice is vital to examining the health disparities that continue to plague many racially and ethnically diverse communities. To date, there is little research on best practices that indicate locations, community areas and settings to engage AA men in research and health promotion. Traditionally, the AA church has been a key area to engage AA men and women. However, changing tides in attendance of AA parishioners require additional information to identify areas where AAs, particularly, AA men congregate. The AA barbershop has been identified as a place of social cohesion, cultural immersion and solidarity for AA men but specific sub-populations of AA men may be underrepresented. To further investigate additional locales where AA men congregate, this study engaged AA barbers and clients in several urban community barbershops in Chicago, Illinois. 127 AA men over age 18y/o receiving grooming services in 25 Chicago area barbershops across 14 predominantly AA communities were consented and recruited for a quantitative survey study. The self-administered surveys were completed in ~15 min and $10 compensation was provided to men. Descriptive statistics were reported for demographic variables and for frequency of responses for locations to find AA men of specific age ranges for health promotion and screening activities. Outside of the traditionally used churches or barbershops, the top recommended recruitment sites by age were: 18–29y/o− city park or a recreational center; 30–39y/o− gym, bars or the street; 40–49y/o− various stores, especially home improvement stores, and the mall; and 50y/o+- fast food restaurants in the mornings, such as McDonalds, and individual’s homes. The study participants also reported that locations where AA men congregate vary by age. Findings from this study illustrate that AA barbers and barbershops remain a key stakeholder in health promotion among AA men. The findings also demonstrate the need for additional research to examine best practices for identifying locations where diverse groups of AA men that vary by age and sexual orientation may congregate in order to support increased health promotion among AA men. PMID:27651166

Alternative Locales for the Health Promotion of African American Men: A Survey of African American Men in Chicago Barbershops.

PubMed

Murphy, A B; Moore, N J; Wright, M; Gipson, J; Keeter, M; Cornelious, T; Reed, D; Russell, J; Watson, K S; Murray, M

2017-02-01

African American men (AA) carry unequal burdens of several conditions including cancer, diabetes, hypertension, and HIV. Engagement of diverse populations including AA men in research and health promotion practice is vital to examining the health disparities that continue to plague many racially and ethnically diverse communities. To date, there is little research on best practices that indicate locations, community areas and settings to engage AA men in research and health promotion. Traditionally, the AA church has been a key area to engage AA men and women. However, changing tides in attendance of AA parishioners require additional information to identify areas where AAs, particularly, AA men congregate. The AA barbershop has been identified as a place of social cohesion, cultural immersion and solidarity for AA men but specific sub-populations of AA men may be underrepresented. To further investigate additional locales where AA men congregate, this study engaged AA barbers and clients in several urban community barbershops in Chicago, Illinois. 127 AA men over age 18y/o receiving grooming services in 25 Chicago area barbershops across 14 predominantly AA communities were consented and recruited for a quantitative survey study. The self-administered surveys were completed in ~15 min and $10 compensation was provided to men. Descriptive statistics were reported for demographic variables and for frequency of responses for locations to find AA men of specific age ranges for health promotion and screening activities. Outside of the traditionally used churches or barbershops, the top recommended recruitment sites by age were: 18-29y/o- city park or a recreational center; 30-39y/o- gym, bars or the street; 40-49y/o- various stores, especially home improvement stores, and the mall; and 50y/o+- fast food restaurants in the mornings, such as McDonalds, and individual's homes. The study participants also reported that locations where AA men congregate vary by age. Findings from this study illustrate that AA barbers and barbershops remain a key stakeholder in health promotion among AA men. The findings also demonstrate the need for additional research to examine best practices for identifying locations where diverse groups of AA men that vary by age and sexual orientation may congregate in order to support increased health promotion among AA men.

45 CFR 1321.45 - Transfer between congregate and home-delivered nutrition service allotments.

Code of Federal Regulations, 2012 CFR

2012-10-01

... nutrition service allotments. 1321.45 Section 1321.45 Public Welfare Regulations Relating to Public Welfare... Responsibilities § 1321.45 Transfer between congregate and home-delivered nutrition service allotments. (a) A State... State's separate allotments for congregate and home-delivered nutrition services. (b) A State agency may...

45 CFR 1321.45 - Transfer between congregate and home-delivered nutrition service allotments.

Code of Federal Regulations, 2011 CFR

2011-10-01

... nutrition service allotments. 1321.45 Section 1321.45 Public Welfare Regulations Relating to Public Welfare... Responsibilities § 1321.45 Transfer between congregate and home-delivered nutrition service allotments. (a) A State... State's separate allotments for congregate and home-delivered nutrition services. (b) A State agency may...

45 CFR 1321.45 - Transfer between congregate and home-delivered nutrition service allotments.

Code of Federal Regulations, 2013 CFR

2013-10-01

... nutrition service allotments. 1321.45 Section 1321.45 Public Welfare Regulations Relating to Public Welfare... Responsibilities § 1321.45 Transfer between congregate and home-delivered nutrition service allotments. (a) A State... State's separate allotments for congregate and home-delivered nutrition services. (b) A State agency may...

45 CFR 1321.45 - Transfer between congregate and home-delivered nutrition service allotments.

Code of Federal Regulations, 2014 CFR

2014-10-01

... nutrition service allotments. 1321.45 Section 1321.45 Public Welfare Regulations Relating to Public Welfare... Responsibilities § 1321.45 Transfer between congregate and home-delivered nutrition service allotments. (a) A State... State's separate allotments for congregate and home-delivered nutrition services. (b) A State agency may...

45 CFR 1321.45 - Transfer between congregate and home-delivered nutrition service allotments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... nutrition service allotments. 1321.45 Section 1321.45 Public Welfare Regulations Relating to Public Welfare... Responsibilities § 1321.45 Transfer between congregate and home-delivered nutrition service allotments. (a) A State... State's separate allotments for congregate and home-delivered nutrition services. (b) A State agency may...

Social Work with Religious Volunteers: Activating and Sustaining Community Involvement

ERIC Educational Resources Information Center

Garland, Diana R.; Myers, Dennis M.; Wolfer, Terry A.

2008-01-01

Social workers in diverse community practice settings recruit and work with volunteers from religious congregations. This article reports findings from two surveys: 7,405 congregants in 35 Protestant congregations, including 2,570 who were actively volunteering, and a follow-up survey of 946 volunteers. It compares characteristics of congregation…

Playing with Mirrors: Narrative Inquiry and Congregational Consultation

ERIC Educational Resources Information Center

Yust, Karen Marie

2009-01-01

This article proposes that narrative inquiry methods fruitfully shape the role and strategies of persons who consult with religious communities. It suggests that the composition of field texts and transition from research notes to narratives enables consultants to mirror the stories of congregations so congregants can recognize, claim, and…

Nutrition knowledge of rural older populations: can congregate meal site participants manage their own diets?

PubMed

Thomas, Lionel; Almanza, Barbara; Ghiselli, Richard

2010-07-01

Congregate meal sites were funded to assist socioeconomically disadvantaged, rural older individuals in improving their health-related practices. Although the participants in the program are largely female, the meals are designed to meet one third of the daily caloric intake of a 70-year-old male, and to satisfy his recommended dietary allowances for total fat, fiber, calcium, and sodium. The actual percentage of the required nutrient intake contributed by meals served at congregate sites is indefinite. Moreover, the ability of congregate meal participants to manage their diets and their receptiveness to helpful nutrition information in that regard is unknown. Our objective was to promote nutritional knowledge in economically disadvantaged, rural older participants by studying its impact on their ability to benefit from congregate meal programs. We used a test, intervention, retest methodology to examine the effect of short-term nutrition interventions on congregate meal site participants' nutrition knowledge. The objective was to determine the participants' potential for managing their own diets (e.g., their ability to determine what diet behaviors are appropriate for specific chronic conditions). We found that while congregate meal site participants have knowledge of nutrition recommendations, their ability to apply this information in helping themselves to prevent or control their chronic conditions remains in question.

Engineering species-like barriers to sexual reproduction.

PubMed

Maselko, Maciej; Heinsch, Stephen C; Chacón, Jeremy M; Harcombe, William R; Smanski, Michael J

2017-10-12

Controlling the exchange of genetic information between sexually reproducing populations has applications in agriculture, eradication of disease vectors, control of invasive species, and the safe study of emerging biotechnology applications. Here we introduce an approach to engineer a genetic barrier to sexual reproduction between otherwise compatible populations. Programmable transcription factors drive lethal gene expression in hybrid offspring following undesired mating events. As a proof of concept, we target the ACT1 promoter of the model organism Saccharomyces cerevisiae using a dCas9-based transcriptional activator. Lethal overexpression of actin results from mating this engineered strain with a strain containing the wild-type ACT1 promoter.Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a 'species-like' barrier to reproduction between two otherwise compatible populations.

Care or Scare: The Safety of Youth in Congregate Care in New York City

ERIC Educational Resources Information Center

Freundlich, Madelyn; Avery, Rosemary J.; Padgett, Deborah

2007-01-01

Objective: This qualitative study examined stakeholders' perceptions of the safety of youth ages 12 and older living in congregate care facilities within the New York City foster care system. The study explored the youth's physical safety, the safety of their personal belongings, the physical conditions of congregate care settings, and the…

Evaluating the efficacy of regionalisation in limiting high-risk livestock trade movements.

PubMed

Hidano, Arata; Carpenter, Tim E; Stevenson, Mark A; Gates, M Carolyn

2016-10-01

Many countries implement regionalisation as a measure to control economically important livestock diseases. Given that regionalisation highlights the difference in disease risk between animal subpopulations, this may discourage herd managers in low-risk areas from purchasing animals from high-risk areas to protect the disease-free status of their herds. Using bovine tuberculosis (bTB) in New Zealand as a case example, we develop a novel network simulation model to predict how much the frequency of cattle movements between different disease control areas (DCAs) could theoretically change if herd managers adopted the safest practices (preferentially purchasing cattle from areas with the lowest risk of bTB), if herd managers adopted the riskiest practices (preferentially purchasing cattle from areas with the greatest risk of bTB), or if herd managers made trade decisions completely at random (purchasing cattle without consideration for bTB disease risk). A modified configuration wiring algorithm was used in the network simulation model to preserve key temporal, spatial, and demographic attributes of cattle movement patterns. The simulated frequencies of cattle movements between DCAs in each of the three behavioural scenarios were compared with the actual frequency of cattle movements that occurred between 1st July 2010 and 30th June 2011. Our results showed that the observed frequency of cattle movements from high-risk areas into low-risk areas was significantly less than if trade decisions were made completely at random, but still significantly greater than if herd managers made the safest possible trade decisions. This suggests that while New Zealand cattle farmers may have adopted risk-averse trading behaviour in response to regionalisation, there are other underlying factors driving livestock trade, such as established supplier-buyer relationships and heterogeneous individual perceptions towards disease risk, which may reduce the potential efficacy of regionalisation as a disease control strategy. Physical constraints and socio-psychological factors that determine herd managers' livestock trading behaviour warrant further studies to better understand how herd managers respond to future livestock disease regulations. The flexibility of a network re-wiring framework presented in this study allows such a behavioural response to be incorporated into a disease simulation model, which will in turn facilitate a better evaluation of disease control strategies. Copyright © 2016 Elsevier B.V. All rights reserved.

Becoming Bioethically Confident: The Contribution of Learning Experiences in Seminary and Congregational Ministry to Evangelical Pastors' Wise Leadership on Bioethical Concerns

ERIC Educational Resources Information Center

Cunningham, Paige Comstock

2017-01-01

This study explores the factors that contribute to evangelical pastors becoming bioethically confident leaders of their congregation. This basic qualitative study invited twenty-five pastors who have a M.Div. or similar seminary degree to share their experiences of theological education, congregational ministry, and their views of pastoral moral…

Social justice and religious participation: a qualitative investigation of Christian perspectives.

PubMed

Todd, Nathan R; Rufa, Anne K

2013-06-01

This investigation examines how self-identified Christians in the Midwest U.S. understand and work for social justice, with a focus on their process of social justice development and the role of religious congregations in promoting social justice. Using a grounded theory analysis of 15 in-depth interviews, results indicated multiple understandings of social justice such as meeting basic needs, fixing social structures and systems to create equal distributions of resources, promoting human rights and dignity, and as a religious responsibility. Participants also described a process of social justice development facilitated by exposure to injustice, mentors, educating others, and the importance of finding a social justice community. Distinct personal barriers to social justice engagement were identified such as resources and negative emotions, whereas congregational leadership was important for congregational involvement. General frustration with congregations was expressed regarding low social justice engagement; however, participants balanced this frustration with hope for the positive potential of congregations to promote social justice. Together these findings show multifaceted understandings of social justice and a dynamic process of social justice development for these self-identified Christians. Implications for future research and partnership with religious individuals and congregations also are discussed.

Religious Congregations' Collaborations: With Whom Do They Work and What Resources Do They Share in Addressing HIV and Other Health Issues?

ERIC Educational Resources Information Center

Werber, Laura; Derose, Kathryn Pitkin; Dominguez, Blanca X.; Mata, Michael A.

2012-01-01

This study explores how religious congregations interact with other community organizations to address health and, in particular, HIV-related needs within their membership and/or local communities. Case study data from a diverse sample of 14 urban congregations (6 Black, 4 Latino, 2 White, and 2 mixed race-ethnicity) indicate that they engaged in…

Correlation between Transformative Learning and Cultural Context: A Case Study of Adult Participants in a Korean American Immigrant Congregation

ERIC Educational Resources Information Center

Kim, Brian Byung Joo

2011-01-01

The purpose of this research was to explore the nature, process, and facilitating factors of transformative learning experiences of Korean-American adults in a Korean American immigrant congregation (KAIC). The focus was on discovering how and to what extent, if any, the congregational culture of the KAIC as the learning situation played a role in…

Religious Congregations’ Involvement in HIV: A Case Study Approach

PubMed Central

Mendel, Peter J.; Palar, Kartika; Kanouse, David E.; Bluthenthal, Ricky N.; Castaneda, Laura Werber; Corbin, Dennis E.; Domínguez, Blanca X.; Hawes-Dawson, Jennifer; Mata, Michael A.; Oden, Clyde W.

2011-01-01

Comparative case studies were used to explore religious congregations’ HIV involvement, including types and extent of activities, interaction with external organizations or individuals, and how activities were initiated and have changed over time. The cases included 14 congregations in Los Angeles County representing diverse faith traditions and races-ethnicities. Activities fell into three broad categories: (1) prevention and education; (2) care and support; and (3) awareness and advocacy. Congregations that engaged early in the epidemic focused on care and support while those that became involved later focused on prevention and education. Most congregations interacted with external organizations or individuals to conduct their HIV activities, but promoting abstinence and teaching about condoms were conducted without external involvement. Opportunities exist for congregations to help address a variety of HIV-related needs. However, activities that are mission-congruent, such as providing pastoral care for people with HIV, raising HIV awareness, and promoting HIV testing, appear easier for congregations to undertake than activities aimed at harm reduction. PMID:20953903

A Tribute to Waiting Room Moms Everywhere

ERIC Educational Resources Information Center

Ansfield, Mara

2008-01-01

Waiting rooms are oases for mothers of children with special needs. They congregate in these small holding areas, sitting on musty couches, while their children receive the latest therapeutic interventions. Sometimes they sit quietly, sneaking glances at each other while pretending to read year-old "People" magazines. Sometimes they crawl under a…

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

24 CFR 51.204 - HUD-assisted hazardous facilities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... area where people may congregate or be present. The mitigating measures listed in § 51.205 may be taken.... 51.204 Section 51.204 Housing and Urban Development Office of the Secretary, Department of Housing... Hazardous Operations Handling Conventional Fuels or Chemicals of an Explosive or Flammable Nature § 51.204...

The organization of HIV and other health activities within urban religious congregations.

PubMed

Palar, Kartika; Mendel, Peter; Derose, Kathryn Pitkin

2013-10-01

Most religious congregations in the USA are involved with some type of social service activity, including health activities. However, relatively few formally engage with people with HIV, and many have reported barriers to introducing HIV prevention activities. We conducted a qualitative case study of HIV involvement among 14 urban congregations in Los Angeles County in 2007. In-depth qualitative interviews of lay leaders and clergy were analyzed for themes related to HIV and other health activities, including types of health issues addressed, types of activities conducted, how activities were organized, and the relationship between HIV and other health activities. We identified three primary models representing how congregations organized HIV and other health activities: (1) embedded (n = 7), where HIV activities were contained within other health activities; (2) parallel (n = 5), where HIV and other health activities occurred side by side and were organizationally distinct; (3) overlap (n = 2), where HIV and non-HIV health efforts were conducted by distinct groups, but shared some members and organization. We discuss implications of each model for initiating and sustaining HIV activities within urban congregations over time.

Epitope characterization of the ADA response directed against a targeted immunocytokine.

PubMed

Stubenrauch, Kay; Künzel, Christian; Vogel, Rudolf; Tuerck, Dietrich; Schick, Eginhard; Heinrich, Julia

2015-10-10

Targeted immunocytokines (TICs) display potent activity in selective tumor suppression. This class of multi domain biotherapeutics (MDBs) is composed of the three major domains Fab, Fc, and a cytokine which may induce a complex polyclonal anti-drug antibody (ADA) response. However, classical ADA assays usually are not suitable to specify ADAs and to identify the immunogenic domains of a TIC. The purpose of the present study was to establish epitope characterization of ADA responses in order to specify immunogenic responses against a TIC and their direct impact on the pharmacokinetic profile, safety, and efficacy. Based on standard ADA screening and confirmation assays, respectively, domain detection assays (DDAs) and domain competition assays (DCAs) were established and compared by the use of 12 ADA-positive samples obtained from a cynomolgus monkey study in early development. Both domain-specific assays were sensitive enough to preserve the positive screening assay result and revealed an overall accordance for the evaluation of domain-specific ADA responses. About half of the samples displayed one ADA specificity, either for the Fab or for the cytokine (Cy) domain, and the remaining samples showed a combination of Fab-specific and Cy-specific ADA fractions. Fc-specific ADAs occurred in only one sample. In-depth comparison of DCAs and DDAs showed that both assays appeared to be appropriate to assess multi-specific ADA responses as well as minor ADA fractions. An advantage of DCAs is typically a fast and easy assay establishment, whereas, DDAs in some cases may be superior to assess low abundant ADAs in multi-specific responses. Our results reveal that both approaches benefit from thorough reagent development as an essential precondition for reliable epitope characterization of ADA responses. Copyright © 2015 Elsevier B.V. All rights reserved.

Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160.

PubMed

Perrin, Arnaud; Rousseau, Joël; Tremblay, Jacques P

2017-03-17

Laminin-111 protein complex links the extracellular matrix to integrin α7β1 in sarcolemma, thus replacing in dystrophic muscles links normally insured by the dystrophin complex. Laminin-111 injection in mdx mouse stabilized sarcolemma, restored serum creatine kinase to wild-type levels, and protected muscles from exercised-induced damages. These results suggested that increased laminin-111 is a potential therapy for DMD. Laminin subunit beta 1 and laminin subunit gamma 1 are expressed in adult human muscle, but laminin subunit alpha 1 (LAMA1) gene is expressed only during embryogenesis. We thus developed an alternative method to laminin-111 protein repeated administration by inducing expression of the endogenous mouse Lama1 gene. This was done with the CRSPR/Cas9 system, i.e., by targeting the Lama1 promoter with one or several gRNAs and a dCas9 coupled with the VP160 transcription activation domain. Lama1 mRNA (qRT-PCR) and proteins (immunohistochemistry and western blot) were not detected in the control C2C12 myoblasts and in control muscles. However, significant expression was observed in cells transfected and in mouse muscles electroporated with plasmids coding for dCas9-VP160 and a gRNA. Larger synergic increases were observed by using two or three gRNAs. The increased Lama1 expression did not modify the expression of the α7 and β1 integrins. Increased expression of Lama1 by the CRISPR/Cas9 system will have to be further investigated by systemic delivery of the CRISPR/Cas9 components to verify whether this could be a treatment for several myopathies. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

75 FR 35478 - Funding Opportunity; Street Outreach Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-22

... congregate, including what times they gather in certain areas, and how many youth are contacted on any given... opportunities during adolescence, a time of rapid growth and change. With this support, they can develop self... of time into which a multi-year period of assistance is divided for budgetary and funding purposes...

African-American Congregational Care and Counseling: Transcending Universal and Culturally-Specific Barriers.

PubMed

Armstrong, Tonya D

2016-06-01

This article addresses two major African-American congregational care needs: (1) helping suffering people to access sustained mental health care, particularly in a large/mega-church; and (2) helping suffering people with multi-layered challenges to access appropriate, skilled care that transcends traditional barriers and is consistent with their faith. One model of congregational care is presented with concrete examples of how cultural, theological, and strategic concerns are discussed, with broad implications for diverse faith communities. © The Author(s) 2016.

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRi) plasmids | Office of Cancer Genomics

Cancer.gov

CTD2 researchers at the University of California in San Francisco developed a modified Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) CRISPR/dCas9 system. Catalytically inactive dCas9 enables modular and programmable RNA-guided genome regulation in eukaryotes.

Benchmarking of TALE- and CRISPR/dCas9-Based Transcriptional Regulators in Mammalian Cells for the Construction of Synthetic Genetic Circuits.

PubMed

Lebar, Tina; Jerala, Roman

2016-10-21

Transcriptional activator-like effector (TALE)- and CRISPR/Cas9-based designable recognition domains represent a technological breakthrough not only for genome editing but also for building designed genetic circuits. Both platforms are able to target rarely occurring DNA segments, even within complex genomes. TALE and dCas9 domains, genetically fused to transcriptional regulatory domains, can be used for the construction of engineered logic circuits. Here we benchmarked the performance of the two platforms, targeting the same DNA sequences, to compare their advantages for the construction of designed circuits in mammalian cells. Optimal targeting strands for repression and activation of dCas9-based designed transcription factors were identified; both platforms exhibited good orthogonality and were used to construct functionally complete NOR gates. Although the CRISPR/dCas9 system is clearly easier to construct, TALE-based activators were significantly stronger, and the TALE-based platform performed better, especially for the construction of layered circuits.

Report to the U.S. Congress on the National Oceanographic Partnership Program

DTIC Science & Technology

2006-03-01

community types that can be associated with hard bottom in areas that may or may not also be associated with living chemosynthetic megafauna (most all hard...species congregate in areas of the sharpest physical gradients , key forcing mechanisms causing variability in the temporal phasing and distribution of...thoroughly the performance by conducting a demonstration experiment at a field site that has strong vertical and horizontal nutrient gradients and

The Relationship Between Cost Growth and Schedule Growth

DTIC Science & Technology

2003-01-01

Relationship between Cost Growth and Schedule Growth, 35th DoDCAS, SCEA 2002, Integrated Program Management Conference (IPMC) 2002, R. L. Coleman...currently valid OMB control number. 1. REPORT DATE 2003 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE The Relationship Between Cost...

Virgin queen attraction toward males in honey bees.

PubMed

Bastin, Florian; Cholé, Hanna; Lafon, Grégory; Sandoz, Jean-Christophe

2017-07-24

Although the honeybee is a crucial agricultural agent and a prominent scientific model organism, crucial aspects of its reproductive behaviour are still unknown. During the mating season, honeybee males, the drones, gather in congregations 10-40 m above ground. Converging evidence suggests that drones emit a pheromone that can attract other drones, thereby increasing the size of the congregation. Virgin queens join the vicinity of the congregation after it has formed, and mate with as many as 20 males in mid-air. It is still unclear which sensory cues help virgin queens find drone congregations in the first place. Beside visual cues for long-range orientation, queens may use olfactory cues. We thus tested virgin queens' olfactory orientation on a walking simulator in which they have full control over odour stimulation. We show that sexually-mature virgin queens are attracted to the odour bouquet from a group of living drones. They are not attracted to the bouquet from a group of workers. In addition, non-sexually receptive females (workers) of the same age are not attracted to the drone odour bouquet. Interpreted in the context of mating, these results may suggest that virgin queens use volatile olfactory cues from the drones to find the congregations.

Voter models with contrarian agents

NASA Astrophysics Data System (ADS)

Masuda, Naoki

2013-11-01

In the voter and many other opinion formation models, agents are assumed to behave as congregators (also called the conformists); they are attracted to the opinions of others. In this study I investigate linear extensions of the voter model with contrarian agents. An agent is either congregator or contrarian and assumes a binary opinion. I investigate three models that differ in the behavior of the contrarian toward other agents. In model 1, contrarians mimic the opinions of other contrarians and oppose (i.e., try to select the opinion opposite to) those of congregators. In model 2, contrarians mimic the opinions of congregators and oppose those of other contrarians. In model 3, contrarians oppose anybody. In all models, congregators are assumed to like anybody. I show that even a small number of contrarians prohibits the consensus in the entire population to be reached in all three models. I also obtain the equilibrium distributions using the van Kampen small-fluctuation approximation and the Fokker-Planck equation for the case of many contrarians and a single contrarian, respectively. I show that the fluctuation around the symmetric coexistence equilibrium is much larger in model 2 than in models 1 and 3 when contrarians are rare.

Black churches and HIV/AIDS: factors influencing congregations’ responsiveness to social issues.

PubMed

Fulton, Brad R

2011-01-01

The ambivalent response of many black churches to current social issues has caused some scholars to question the centrality of black churches within African-American communities. Using a nationally representative sample of black congregations, this study engages the debate about the institutional centrality of black churches by focusing on their response to HIV/AIDS. Although many congregational studies treat black churches as a monolithic whole, this analysis identifies heterogeneity among black churches that shapes their responsiveness to social issues. Contrary to prior claims, a congregation's liberal-conservative ideological orientation does not significantly affect its likelihood of having an HIV/AIDS program. Beyond assessing churches’ internal characteristics, this study uses institutional theory to analyze churches as open systems that can be influenced by their surrounding environment. It demonstrates that externally engaged congregations are significantly more likely to have a program. These results indicate that black churches maintain institutional centrality by engaging their external environment.

The CASA Dallas Fort Worth Remote Sensing Network ICT for Urban Disaster Mitigation

NASA Astrophysics Data System (ADS)

Chandrasekar, Venkatachalam; Chen, Haonan; Philips, Brenda; Seo, Dong-jun; Junyent, Francesc; Bajaj, Apoorva; Zink, Mike; Mcenery, John; Sukheswalla, Zubin; Cannon, Amy; Lyons, Eric; Westbrook, David

2013-04-01

The dual-polarization X-band radar network developed by the U.S. National Science Foundation Engineering Center for Collaborative Adaptive Sensing of the Atmosphere (CASA) has shown great advantages for observing and prediction of hazardous weather events in the lower atmosphere (1-3 km above ground level). The network is operating though a scanning methodology called DCAS, distributed collaborative adaptive sensing, which is designed to focus on particular interesting regions of the atmosphere and disseminate information for decision-making to multiple end-users, such as emergency managers and policy analysts. Since spring 2012, CASA and the North Central Texas Council of Governments (NCTCOG) have embarked the development of Dallas Fort Worth (DFW) urban remote sensing network, including 8-node of dual-polarization X-band radars, in the populous DFW Metroplex (pop. 6.3 million in 2010). The main goal of CASA DFW urban demonstration network is to protect the safety and prosperity of humans and ecosystems through research activities that include: 1) to demonstrate the DCAS operation paradigm developed by CASA; 2) to create high-resolution, three-dimensional mapping of the meteorological conditions; 3) to help the local emergency managers issue impacts-based warnings and forecasts for severe wind, tornado, hail, and flash flood hazards. The products of this radar network will include single and multi-radar data, vector wind retrieval, quantitative precipitation estimation and nowcasting, and numerical weather predictions. In addition, the high spatial and temporal resolution rainfall products from CASA can serve as a reliable data input for distributed hydrological models in urban area. This paper presents the information and communication link between radars, rainfall product generation, hydrologic model link and end user community in the Dallas Fort Worth Urban Network. Specific details of the Information and Communication Technologies (ICT) between the various subsystems are presented.

The Feagaiga and Faife'au 'Kids' (FKs): An Examination of the Experiences of Parsonage Children of the Samoan Congregational Denomination in New Zealand.

PubMed

Muaiava, Sadat Petelo

2017-03-01

This article examines the experiences of faife'au 'kids' (clergy children) of the Samoan Congregational Christian Church denomination in New Zealand. The paper investigates the effects the indigenous concept of feagaiga (covenant) has on faife'au kids (FKs) parsonage experiences. Additionally, the Eurocentric concept of 'tagata'ese' (stranger) is also investigated. As part of a master's research study, Talanoa sessions were conducted with eight FKs of the Congregational denomination in New Zealand. Participants were mainly from the Wellington and Auckland regions.

The Lands of New Mexico.

ERIC Educational Resources Information Center

Swadesh, Frances Leon; And Others

New Mexico, the fifth largest state, measures 390 miles from north to south and 350 miles from east to west. Six of the 7 life zones found in the U.S. are represented within the State's 77,866,240 acres. Its population has tended to congregate at altitudes of 7,000 feet and below, especially in areas where water is available. This booklet,…

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRi) plasmids | Office of Cancer Genomics

Cancer.gov

CTD2 researchers at the University of California in San Francisco developed a modified Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) CRISPR/dCas9 system. Catalytically inactive dCas9 enables modular and programmable RNA-guided genome regulation in eukaryotes.

A CRISPR/molecular beacon hybrid system for live-cell genomic imaging.

PubMed

Wu, Xiaotian; Mao, Shiqi; Yang, Yantao; Rushdi, Muaz N; Krueger, Christopher J; Chen, Antony K

2018-04-30

The clustered regularly interspersed short palindromic repeat (CRISPR) gene-editing system has been repurposed for live-cell genomic imaging, but existing approaches rely on fluorescent protein reporters, making sensitive and continuous imaging difficult. Here, we present a fluorophore-based live-cell genomic imaging system that consists of a nuclease-deactivated mutant of the Cas9 protein (dCas9), a molecular beacon (MB), and an engineered single-guide RNA (sgRNA) harboring a unique MB target sequence (sgRNA-MTS), termed CRISPR/MB. Specifically, dCas9 and sgRNA-MTS are first co-expressed to target a specific locus in cells, followed by delivery of MBs that can then hybridize to MTS to illuminate the target locus. We demonstrated the feasibility of this approach for quantifying genomic loci, for monitoring chromatin dynamics, and for dual-color imaging when using two orthogonal MB/MTS pairs. With flexibility in selecting different combinations of fluorophore/quencher pairs and MB/MTS sequences, our CRISPR/MB hybrid system could be a promising platform for investigating chromatin activities.

Evangelical Church polity and the nuances of white flight: a case study from the Roseland and Englewood neighborhoods in Chicago.

PubMed

Mulder, Mark T

2012-01-01

Present patterns of residential segregation have been proven to have antecedents in the so-called white flight of the 1950s, 1960s, and 1970s. Close scrutiny of this social phenomenon has yielded results that indicate complicated impetuses and call into question sweeping assumptions about white flight. A case study of seven congregations from a denomination called the Christian Reformed Church in North America (CRC) who left the Englewood and Roseland neighborhoods of Chicago during the juncture in question further reveals the dubious role of religious practices and arrangements in the out-migration of white evangelical Christians. By utilizing church histories, council minutes, and field interviews, it became readily apparent that the departure of the members of these congregations found sanction within the hierarchical apparatus (or lack thereof) of the church. The response of these CRC congregations exemplified how the political structures (congregational polity) and social networks of a particular denomination could allow for an almost seamless process of white flight.

Glutaric aciduria type I and methylmalonic aciduria: simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood-brain barrier and the choroid plexus.

PubMed

Sauer, Sven W; Opp, Silvana; Mahringer, Anne; Kamiński, Marcin M; Thiel, Christian; Okun, Jürgen G; Fricker, Gert; Morath, Marina A; Kölker, Stefan

2010-06-01

Intracerebral accumulation of neurotoxic dicarboxylic acids (DCAs) plays an important pathophysiological role in glutaric aciduria type I and methylmalonic aciduria. Therefore, we investigated the transport characteristics of accumulating DCAs - glutaric (GA), 3-hydroxyglutaric (3-OH-GA) and methylmalonic acid (MMA) - across porcine brain capillary endothelial cells (pBCEC) and human choroid plexus epithelial cells (hCPEC) representing in vitro models of the blood-brain barrier (BBB) and the choroid plexus respectively. We identified expression of organic acid transporters 1 (OAT1) and 3 (OAT3) in pBCEC on mRNA and protein level. For DCAs tested, transport from the basolateral to the apical site (i.e. efflux) was higher than influx. Efflux transport of GA, 3-OH-GA, and MMA across pBCEC was Na(+)-dependent, ATP-independent, and was inhibited by the OAT substrates para-aminohippuric acid (PAH), estrone sulfate, and taurocholate, and the OAT inhibitor probenecid. Members of the ATP-binding cassette transporter family or the organic anion transporting polypeptide family, namely MRP2, P-gp, BCRP, and OATP1B3, did not mediate transport of GA, 3-OH-GA or MMA confirming the specificity of efflux transport via OATs. In hCPEC, cellular import of GA was dependent on Na(+)-gradient, inhibited by NaCN, and unaffected by probenecid suggesting a Na(+)-dependent DCA transporter. Specific transport of GA across hCPEC, however, was not found. In conclusion, our results indicate a low but specific efflux transport for GA, 3-OH-GA, and MMA across pBCEC, an in vitro model of the BBB, via OAT1 and OAT3 but not across hCPEC, an in vitro model of the choroid plexus. Copyright 2010 Elsevier B.V. All rights reserved.

Yield Improvement of the Anti-MRSA Antibiotics WAP-8294A by CRISPR/dCas9 Combined with Refactoring Self-Protection Genes in Lysobacter enzymogenes OH11.

PubMed

Yu, Lingjun; Su, Wei; Fey, Paul D; Liu, Fengquan; Du, Liangcheng

2018-01-19

The cyclic lipodepsipeptides WAP-8294A are antibiotics with potent activity against methicillin-resistant Staphylococcus aureus (MRSA). One member of this family, WAP-8294A2 (Lotilibcin), was in clinical trials due to its high activity and distinct chemistry. However, WAP-8294A compounds are produced in a very low yield by Lysobacter and only under very stringent conditions. Improving WAP-8294A yield has become very critical for research and application of these anti-MRSA compounds. Here, we report a strategy to increase WAP-8294A production. We first used the CRISPR/dCas9 system to increase the expression of five cotranscribed genes (orf1-5) in the WAP gene cluster, by fusing the omega subunit of RNA polymerase with dCas9 that targets the operon's promoter region. This led to the transcription of the genes increased by 5-48 folds in strain dCas9-ω3. We then refactored four putative self-protection genes (orf6, orf7, orf9 and orf10) by reorganizing them into an operon under the control of a strong Lysobacter promoter, P HSAF . The refactored operon was introduced into strain dCas9-ω3, and the transcription of the self-protection genes increased by 20-60 folds in the resultant engineered strains. The yield of the three main WAP-8294A compounds, WAP-8294A1, WAP-8294A2, and WAP-8294A4, increased by 6, 4, and 9 folds, respectively, in the engineered strains. The data also showed that the yield increase of WAP-8294A compounds was mainly due to the increase of the extracellular distribution. WAP-8294A2 exhibited potent (MIC 0.2-0.8 μg/mL) and specific activity against S. aureus among a battery of clinically relevant Gram-positive pathogens (54 isolates).

Dimensions of Religion, Depression Symptomatology, and Substance Use Among Rural African American Cocaine Users

PubMed Central

Montgomery, Brooke E. E.; Stewart, Katharine E.; Bryant, Keneshia J.; Ounpraseuth, Songthip T.

2014-01-01

Research has shown a relationship between depression, substance use, and religiosity but, few have investigated this relationship in a community sample of drug-using African Americans. This study examined the relationship between dimensions of religion (positive and negative religious coping, private and public religious participation, religious preference, and God-based, clergy-based, and congregation-based religious support), depression symptomatology, and substance use among 223 African American cocaine users. After controlling for gender, employment, and age, greater congregation-based support and greater clergy-based support were associated with fewer reported depressive symptoms. Additionally, greater congregation-based support was associated with less alcohol use. PMID:24564561

Ethical Becoming: Adult Ethical Development in Christian Congregations

ERIC Educational Resources Information Center

Carr-Chellman, Davin J.

2011-01-01

This is a study of adult ethical development in Christian congregations. Using an empirical hermeneutic phenomenological methodology, this study examined how five pastors understand and encourage ethical development, developing an in-depth analysis and interpretation of their perceptions of the phenomenon of adult ethical development. Two primary…

"As a Community, We Need to be More Health Conscious": Pastors' Perceptions on the Health Status of the Black Church and African-American Communities.

PubMed

Gross, Tyra Toston; Story, Chandra R; Harvey, Idethia Shevon; Allsopp, Marie; Whitt-Glover, Melicia

2018-06-01

Churches are recognized for their potential capacity to provide health services and interventions to address health disparities in African-Americans (blacks). Since pastors are central community leaders, their support and involvement can influence both implementation and outcomes for church-based health programs. The purpose of this qualitative study was to explore pastors' perceptions of congregant health status within the black church. Semi-structured interviews were conducted with 11 pastors whose female congregants participated in a physical activity intervention. Thematic analysis techniques were used to analyze interview data. Three major themes emerged: (1) health risks in the African-American community, (2) health promotion in the black church, and (3) the importance of women in the black family and the church. Pastors noted numerous health disparities affecting their congregants and the African-American community at large, including obesity and infant mortality. They viewed health holistically and included faith in their perspectives. According to pastors, holistic health was promoted through health ministry programming in black churches. Women were described as the cornerstone of the black church, yet faced unique health concerns from their roles as family caretakers and congregants. Pastors shared their major concerns for congregant health status and the African-American community. Health interventions focusing on African-Americans in church settings should include pastor involvement and should incorporate holistic approaches to address health risks.

Healthy Eating Exploratory Program for the Elderly: Low Salt Intake in Congregate Meal Service.

PubMed

Seo, S; Kim, O Y; Ahn, J

2016-03-01

This study reported on an exploratory program to help the low income elderly improve healthy eating behavior, specifically by reducing salt intake. We conducted an exploratory program for 4 weeks for this study. The exploratory program involved offering menus with reduced salt and providing education on healthy eating. After the exploratory program, a survey of the elderly and in-depth interviews allowed us to evaluate the program for foodservice providers (dietitian, social workers, and volunteer workers). This study included both foodservice workers and elderly who actually used the foodservice in a congregate meal service system. This is a unique approach. A congregate meal service center in Seoul, Korea. Seventy four elderly in a congregate meal service center. Demographics were collected, and the healthy eating program and healthy eating education for elderly respondents were evaluated. The elderly showed high satisfaction with the exploratory program for healthy eating. We found no significant differences in satisfaction with the program between the elderly who attended education sessions and those who did not, but more of the elderly from the education sessions showed positive behavioral change intentions. The exploratory program influenced to reduce the salt intake of the elderly in congregate meal service. This study suggests cooperation of foodservice providers and the support of administrators is critical to the success of such programs.

Applying the 15 Public Health Emergency Preparedness Capabilities to Support Large-Scale Tuberculosis Investigations in Complex Congregate Settings

PubMed Central

Toren, Katelynne Gardner; Elsenboss, Carina; Narita, Masahiro

2017-01-01

Public Health—Seattle and King County, a metropolitan health department in western Washington, experiences rates of tuberculosis (TB) that are 1.6 times higher than are state and national averages. The department’s TB Control Program uses public health emergency management tools and capabilities sustained with Centers for Disease Control and Prevention grant funding to manage large-scale complex case investigations. We have described 3 contact investigations in large congregate settings that the TB Control Program conducted in 2015 and 2016. The program managed the investigations using public health emergency management tools, with support from the Preparedness Program. The 3 investigations encompassed medical evaluation of more than 1600 people, used more than 100 workers, identified nearly 30 individuals with latent TB infection, and prevented an estimated 3 cases of active disease. These incidents exemplify how investments in public health emergency preparedness can enhance health outcomes in traditional areas of public health. PMID:28892445

76 FR 23964 - Fisheries in the Western Pacific; Pelagic Fisheries; Purse Seine Prohibited Areas Around American...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-29

... animals, such as pelagic fishes and sea turtles, tend to congregate to naturally-occurring floating... American Samoa enclosed by straight lines connecting the following coordinates: Point S. latitude W. longitude AS-3-A 11[deg]12[min] 172[deg]18[min] AS-3-B 12[deg]12[min] 169[deg]56[min] and from Point AS-3-A...

Tested in the Faith Community: The Congregational Hermeneutics of the Mennonites.

ERIC Educational Resources Information Center

Siebert, Bradley G.

The social epistemic that the Mennonite-Anabaptists have been cultivating as their hermeneutic method for 470 years focuses on local congregations as discourse communities of faith, promoting egalitarian lay participation equal to that of members with formal ministries. "The Confession of Faith in a Mennonite Perspective" features a…

Welcome the Child: A Child Advocacy Guide for Churches. Revised and Expanded Edition.

ERIC Educational Resources Information Center

Daley, Shannon P.; Guy, Kathleen A.

This guide is intended to help church congregations develop and/or strengthen plans for children's ministries and child advocacy. Specifically the work aims to affirm children's growth, discoveries, and experiences and to provide strategies to congregations for helping children whose physical, emotional, social, economic, and educational…

Targeting BRCAness in Gastric Cancer

DTIC Science & Technology

2017-10-01

modified CRISPR system using dCas9-KRAB expressing variants of these cells, and validated them for CRISPRi screening. These reagents will next be used...OE19 Adherent Stable Oesophagus/ gastric cardia - - - OE33 Adherent Stable Esophageal adenocarcinoma - - - Figure 2. Validation of CRISPR ...project planning and reporting Patrick O’Leary Postdoctoral Fellow UCSF PH.D. Design, execution, and interpretation of CRISPR experiments

Evaluating the Functional Utility of Congregate Day Treatment Activities for Adults with Severe Disabilities.

ERIC Educational Resources Information Center

Reid, Dennis H.; Parsons, Marsha B.; Green, Carolyn W.

2001-01-01

Observations in 100 congregated community and institutional day-program sites for individuals with severe disabilities indicated that approximately half of consumer time was spent in purposeful activity, 75 percent of which was age-appropriate. In 20 percent of the sites most activity was age-inappropriate. Recommended program evaluation and…

Teaching through Personal Stories: Congregational Rabbis and Teaching Adults

ERIC Educational Resources Information Center

Tauber, Sarah M.

2013-01-01

As educators, synagogue rabbis frequently devote a great deal of time to teaching adults. Yet little empirical research exists about what they do. This study describes and analyzes the teaching of three congregational rabbis who have excellent reputations as teachers of adults. In particular, it focuses on how these rabbis incorporate personal…

An Intergenerational Partnership between a College and Congregate Housing Facility: How It Works, What It Means.

ERIC Educational Resources Information Center

Krout, John A.; Pogorzala, Christine H.

2002-01-01

Describes the goals, development, operation, and outcomes of an intergenerational programmatic relationship between a private college and a congregate facility for older adults. Faculty and students report that partnership activities provide excellent opportunities for increasing the understanding of aging and older adults. Residents report…

Let's Lunch and Learn: Professional Knowledge Sharing in Teachers' Lounges and Other Congregational Spaces

ERIC Educational Resources Information Center

Mawhinney, Lynnette

2010-01-01

Teachers' lounges are often thought as places that breed negativity. This two-year ethnography conducted in the United States explored teachers' interactions within teachers' lounges and congregational spaces. This article discusses that an important occurrence in these spaces, professional knowledge sharing, took place instead of perpetual…

Contribution of the Vincentians to Catholic Education in Ireland and England

ERIC Educational Resources Information Center

McCann, Joseph

2014-01-01

This article is an account of the actions and achievements, i.e. the "contribution", of the Ireland Province of the Vincentian Congregation, known officially as "the Congregation of the Mission", in respect of Catholic education in Ireland and England. The approach is, first, to outline the motives and intentions of the…

Perceived Barriers to Optimum Nutrition among Congregate (Sheltered) Housing Residents in the USA

ERIC Educational Resources Information Center

Mahadevan, Meena; Hartwell, Heather; Feldman, Charles; Raines, Emily

2014-01-01

Objective: Malnutrition, secondary to decreased food intake, is a public health problem of epidemic proportions among older adults in the United States of America (USA). Compared to community-dwelling senior citizens, congregate (sheltered) housing residents are found to be frailer, with documented deficiencies in several major and minor…

Amachi: Mentoring Children of Prisoners in Philadelphia.

ERIC Educational Resources Information Center

Jucovy, Linda

This report documents the work of Amachi, a mentoring program for children of incarcerated and formerly incarcerated parents in Philadelphia, Pennsylvania. Volunteers are recruited from inner-city congregations to provide one-to-one mentoring to the children. Beyond being the source of mentors, the congregations are a key part of the initiative.…

From a Distance: Pastoral Care and Theological Education

ERIC Educational Resources Information Center

Elias, Jacob W.

2006-01-01

This article is a presentation and discussion of a seminary course on the Corinthian Correspondence. The pedagogical model for this course was structured to parallel the pattern of Paul's pastoral care from a distance as he relates to the Corinthian congregation by personal visits, delegations from and to the congregation, letters from and to the…

24 CFR 982.609 - Congregate housing: Housing quality standards.

Code of Federal Regulations, 2011 CFR

2011-04-01

... food waste and refuse, including facilities for temporary storage where necessary. Group Home ... apply in place of § 982.401(c) (food preparation and refuse disposal). Congregate housing is not subject to the HQS acceptability requirement in § 982.401(d)(2)(i) that the dwelling unit must have a kitchen...

24 CFR 982.609 - Congregate housing: Housing quality standards.

Code of Federal Regulations, 2014 CFR

2014-04-01

... food waste and refuse, including facilities for temporary storage where necessary. Group Home ... apply in place of § 982.401(c) (food preparation and refuse disposal). Congregate housing is not subject to the HQS acceptability requirement in § 982.401(d)(2)(i) that the dwelling unit must have a kitchen...

24 CFR 982.609 - Congregate housing: Housing quality standards.

Code of Federal Regulations, 2012 CFR

2012-04-01

... food waste and refuse, including facilities for temporary storage where necessary. Group Home ... apply in place of § 982.401(c) (food preparation and refuse disposal). Congregate housing is not subject to the HQS acceptability requirement in § 982.401(d)(2)(i) that the dwelling unit must have a kitchen...

24 CFR 982.609 - Congregate housing: Housing quality standards.

Code of Federal Regulations, 2013 CFR

2013-04-01

... food waste and refuse, including facilities for temporary storage where necessary. Group Home ... apply in place of § 982.401(c) (food preparation and refuse disposal). Congregate housing is not subject to the HQS acceptability requirement in § 982.401(d)(2)(i) that the dwelling unit must have a kitchen...

U.S. Clergy Religious Values and Relationships to End-of-Life Discussions and Care.

PubMed

Balboni, Michael J; Sullivan, Adam; Enzinger, Andrea C; Smith, Patrick T; Mitchell, Christine; Peteet, John R; Tulsky, James A; VanderWeele, Tyler; Balboni, Tracy A

2017-06-01

Although clergy interact with approximately half of U.S. patients facing end-of-life medical decisions, little is known about clergy-congregant interactions or clergy influence on end-of-life decisions. The objective was to conduct a nationally representative survey of clergy beliefs and practices. A mailed survey to a nationally representative sample of clergy completed in March 2015 with 1005 of 1665 responding (60% response rate). The primary predictor variable was clergy religious values about end-of-life medical decisions, which measured belief in miracles, the sanctity of life, trust in divine control, and redemptive suffering. Outcome variables included clergy-congregant end-of-life medical conversations and congregant receipt of hospice and intensive care unit (ICU) care in the final week of life. Most U.S. clergy are Christian (98%) and affirm religious values despite a congregant's terminal diagnosis. Endorsement included God performing a miracle (86%), pursuing treatment because of the sanctity of life (54%), postponement of medical decisions because God is in control (28%), and enduring painful treatment because of redemptive suffering (27%). Life-prolonging religious values in end-of-life medical decisions were associated with fewer clergy-congregant conversations about considering hospice (adjusted odds ratio [AOR], 0.58; 95% CI 0.42-0.80), P < 0.0001), stopping treatment (AOR 0.58, 95% CI 0.41-0.84, P = 0.003), and forgoing future treatment (AOR 0.50, 95% CI 0.36-0.71, P < 0.001) but not associated with congregant receipt of hospice or ICU care. Clergy with lower medical knowledge were less likely to have certain end-of-life conversations. The absence of a clergy-congregant hospice discussion was associated with less hospice (AOR 0.45; 95% CI 0.29-0.66, P < 0.001) and more ICU care (AOR 1.67; 95% CI 1.14-2.50, P < 0.01) in the final week of life. American clergy hold religious values concerning end-of-life medical decisions, which appear to decrease end-of-life discussions. Clergy end-of-life education may enable better quality end-of-life care for religious patients. Copyright © 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

Targeting BRCAness in Gastric Cancer

DTIC Science & Technology

2017-10-01

generated a modified CRISPR system using dCas9-KRAB expressing variants of these cells, and validated them for CRISPRi screening. These reagents will...adenocarcinoma - - - Figure 2. Validation of CRISPR activity following transduction with sgRNAs targeting CD55 and FACS staining with the anti...execution, and interpretation of CRISPR experiments Morgan Diolaiti Specialist UCSF PH.D. Experimental planning and reporting Jefferson Woods SRA

CRISPR-on system for the activation of the endogenous human INS gene.

PubMed

Giménez, C A; Ielpi, M; Mutto, A; Grosembacher, L; Argibay, P; Pereyra-Bonnet, F

2016-06-01

Advances in the field of epigenetics have allowed the design of new therapeutic strategies to address complex diseases such as type 1 diabetes (T1D). Clustered regularly interspaced short palindromic repeats (CRISPR)-on is a novel and powerful RNA-guided transcriptional activator system that can turn on specific gene expression; however, it remains unclear whether this system can be widely used or whether its use will be restricted depending on cell types, methylation promoter statuses or the capacity to modulate chromatin state. Our results revealed that the CRISPR-on system fused with transcriptional activators (dCas9-VP160) activated endogenous human INS, which is a silenced gene with a fully methylated promoter. Similarly, we observed a synergistic effect on gene activation when multiple single guide RNAs were used, and the transcriptional activation was maintained until day 21. Regarding the epigenetic profile, the targeted promoter gene did not exhibit alteration in its methylation status but rather exhibited altered levels of H3K9ac following treatment. Importantly, we showed that dCas9-VP160 acts on patients' cells in vitro, particularly the fibroblasts of patients with T1D.

Achieving Broad Participation in Congregational Health Surveys at African American and Latino Churches

ERIC Educational Resources Information Center

Hawes-Dawson, Jennifer; Derose, Kathryn P.; Aunon, Frances M.; Dominguez, Blanca X.; Felton, Alexandria; Mata, Michael A.; Oden, Clyde W.; Paffen, Sandra

2017-01-01

Congregation-based health program evaluations often rely on surveys, but little documentation is available regarding specific methods and challenges. Here we describe methods used to achieve acceptable response rates (73-79%) in a survey of HIV-related attitudes and behaviors in two African American and three Latino churches in high HIV-prevalence…

Early 20th Century Education in the United States: The Role of the Brothers of Holy Cross

ERIC Educational Resources Information Center

Armstrong, Philip C.

2007-01-01

The French Revolution bears an ironic responsibility for generating works of charity. To counteract the devastating social effects of that late 18th century uprising, numerous religious communities were founded in France, among them the Congregation of Holy Cross. The Congregation of Holy Cross, the founding religious community behind the…

Estimating bighorn sheep (Ovis Canadensis) abundance using noninvasive sampling at a mineral lick within a national park wilderness area

Treesearch

Kathryn A. Schoenecker; Mary Kay Watry; Laura E. Ellison; Michael K. Schwartz; Gordon L. Luikart

2015-01-01

Conservation of species requires accurate population estimates. We used genetic markers from feces to determine bighorn sheep abundance for a herd that was hypothesized to be declining and in need of population status monitoring. We sampled from a small but accessible portion of the population’s range where animals naturally congregate at a natural mineral lick to test...

The Contribution of the Holy Ghost Congregation to the Educational Development of Nigeria: Historical and Contemporary Reflections

ERIC Educational Resources Information Center

Amadi, Anthony

2016-01-01

This article is a historical narrative about the contribution the Holy Ghost Congregation made in the educational development of Nigeria. It is narrative because it highlights the events and the work of the early Spiritan missionaries that brought education and its benefits to Nigerians. It is pedagogic because it describes the methods these Holy…

Getting the Books Off the Shelves. Making the Most of Your Congregation's Library. Revised Edition. CSLA Guide No. 12.

ERIC Educational Resources Information Center

Smith, Ruth S.

This guide provides guidelines for promoting and attracting users to a church library. The first of six chapters, "Promoting Library Use," discusses stages of promotion, methods of attracting the attention and interest of prospective users, and how to involve members of the congregation in library activities; the second chapter, "Publicizing the…

Private Catholic Elementary Schools Established by Religious Congregations in the United States: Emerging Governance Models

ERIC Educational Resources Information Center

Walsh, Mary Grace

2010-01-01

Private Catholic elementary schools in the United States often trace their origins to religious congregations of women and men. The rapid decline of religious vocations and the choice of many religious to serve in diverse ministries since the Second Vatican Council, has had an effect on all Catholic schools. Schools founded by religious…

Gender and morals in Spanish Catholic youth culture: a case study of the Marian Congregations 1930-1936.

PubMed

Vincent, M

2001-01-01

Jesuit-run Marian Congregations proliferated in 1930s Spain. Drawing on literature produced for their members, this article demonstrates how gendered understandings were fundamental to the congregations' symbolic delineation of an uncontaminated Catholic space. Visions of an incorrupt male elite abound, reinforcing the Jesuits' educational mission among future leaders and opinion-formers. In contrast, the purity of women and children was seen as a sign of society's moral health. Modesty was the quintessential female virtue. Yet, the cult of the Virgin Mary suggested that the virginal female body was both tool and symbol in the struggle against a fallen world. Girls were, therefore, charged with the task of moral guardianship. Such campaigns were emblematic of Spanish Catholicism's tendency to proffer religious solutions to social problems.

Targeting BRCAness in Gastric Cancer

DTIC Science & Technology

2017-10-01

modified CRISPR system using dCas9-KRAB expressing variants of these cells, and validated them for CRISPRi screening. These reagents will next be... CRISPR activity following transduction with sgRNAs targeting CD55 and FACS staining with the anti-CD55 antibody. Data shown for MKN7 and KATOIII...Oversight, project planning and reporting Patrick O’Leary Postdoctoral Fellow UCSF PH.D. Design, execution, and interpretation of CRISPR experiments

Targeting BRCAness in Gastric Cancer

DTIC Science & Technology

2017-10-01

a modified CRISPR system using dCas9-KRAB expressing variants of these cells, and validated them for CRISPRi screening. These reagents will next be... CRISPR activity following transduction with sgRNAs targeting CD55 and FACS staining with the anti-CD55 antibody. Data shown for MKN7 and KATOIII...Oversight, project planning and reporting Patrick O’Leary Postdoctoral Fellow UCSF PH.D. Design, execution, and interpretation of CRISPR

The Congregation for Catholic Education: How It Works to Support the Educational Mission of Universities and Schools Internationally

ERIC Educational Resources Information Center

Grocholewski, H. E. Zenon

2015-01-01

The Congregation for Catholic Education is a part of the government of the Holy See. The genesis of this Dicastery can be traced to special commissions created by the Roman Pontiffs for maintaining vigilance over the universities in Rome and other educational institutions in the Papal States. A general overview of the history of the Congregation…

Changes in the Self-Rated Well-Being of People Who Move from Congregated Settings to Personalized Arrangements and Group Home Placements

ERIC Educational Resources Information Center

McConkey, Roy; Keogh, Fiona; Bunting, Brendan; Iriarte, Edurne Garcia

2018-01-01

A natural experiment contrasted the self-rated well-being of people with intellectual disabilities (n = 75) and those with enduring mental health problems (n = 44) after they moved to new accommodation and support options, while others remained in congregated settings or living in the family home. Most support staff also provided well-being…

Exploring religious mechanisms for healthy alcohol use: religious messages and drinking among Korean women in California.

PubMed

Ayers, John W; Hofstetter, C Richard; Hughes, Suzanne C; Irvin, Veronica L; Sim, D Eastern Kang; Hovell, Melbourne F

2009-11-01

This research identifies social reinforcers within religious institutions associated with alcohol consumption among Korean women in California. Data were drawn from telephone interviews with female adults (N = 591) selected from a random sampling of persons in California with Korean surnames during 2007. Approximately 70% of attempted interviews were completed, with 92% conducted in Korean. Respondents were asked about any lifetime drinking (yes/no), drinking rate (typical number of drinks consumed on drinking days among current drinkers), and messages discouraging "excessive drinking" from religious leaders or congregants. Bivariable and multivariable regressions were used for analysis. Approximately 70.4% of women reported any lifetime drinking, and drinkers drank a mean (SD) of 1.10 (1.22) drinks on drinking days. About 30.8% reported any exposure to religious leaders' messages discouraging excessive drinking, and 28.2% reported any exposure to similar messages from congregants. Each congregant's message was statistically significantly associated with a 5.1% lower probability (odds ratio = 0.775, 95% confidence interval [CI]: 0.626, 0.959) of any lifetime drinking. also, each congregant's message was associated with a 13.8% (B = -0.138; 95% CI: -0.306, 0.029) lower drinking rate, which was statistically significant after adjusting for covariates using a one-tailed test. Exposure to leaders' messages was not statistically significantly associated with any lifetime drinking or drinking rate. Social reinforcement in the form of religious messages may be one mechanism by which religious institutions influence drinking behaviors. For Korean women, messages from congregants had a unique impact beyond the traditional religiosity indicators. These social mechanisms provide public health interventionists with religious pathways to improve drinking behaviors.

Exploring Religious Mechanisms for Healthy Alcohol Use: Religious Messages and Drinking Among Korean Women in California*

PubMed Central

Ayers, John W.; Hofstetter, C. Richard; Hughes, Suzanne C.; Irvin, Veronica L.; Kang Sim, D. Eastern; Hovell, Melbourne F.

2009-01-01

Objective: This research identifies social reinforcers within religious institutions associated with alcohol consumption among Korean women in California. Method: Data were drawn from telephone interviews with female adults (N = 591) selected from a random sampling of persons in California with Korean surnames during 2007. Approximately 70% of attempted interviews were completed, with 92% conducted in Korean. Respondents were asked about any lifetime drinking (yes/no), drinking rate (typical number of drinks consumed on drinking days among current drinkers), and messages discouraging “excessive drinking” from religious leaders or congregants. Bivariable and multivariable regressions were used for analysis. Results: Approximately 70.4% of women reported any lifetime drinking, and drinkers drank a mean (SD) of 1.10 (1.22) drinks on drinking days. About 30.8%reported about 30.8% reported any exposure to religious leaders' messages discouraging excessive drinking, and 28.2% reported any exposure to similar messages from congregants. Each congregant's message was statistically significantly associated with a 5.1% lower probability (odds ratio = 0.775, 95% confidence interval [CI]: 0.626, 0.959) of any lifetime drinking. Also, each congregant's message was associated with a 13.8% (B = -0.138; 95% CI: -0.306, 0.029) lower drinking rate, which was statistically significant after adjusting for covariates using a one-tailed test. Exposure to leaders' messages was not statistically significantly associated with any lifetime drinking or drinking rate. Conclusions: Social reinforcement in the form of religious messages may be one mechanism by which religious institutions influence drinking behaviors. For Korean women, messages from congregants had a unique impact beyond the traditional religiosity indicators. These social mechanisms provide public health interventionists with religious pathways to improve drinking behaviors. PMID:19895765

10-Year Study of Christian Church Support for Domestic Violence Victims: 2005-2015.

PubMed

Zust, Barbara; Flicek, Breanna; Moses, Katie; Schubert, Courtney; Timmerman, Jessica

2018-02-01

Religious beliefs play a significant role in the lives of victims of domestic violence. Victims find strength in their faith and would rather endure the violence at all costs to keep a family or a marriage together, than to compromise their faith by leaving. This 10 -year study explored the climate of support for victims of domestic violence among Christian clergy and church members between 2005 and 2015. Using a convenience sample, surveys were sent out to congregations in the Upper Midwest in 2005 and 2015. The survey included demographics; two items measuring perception of domestic violence in the congregation andcommunity; six Likert Scale items regarding agreement with statements concerning leaving an abusive marriage; four 'Yes-No' items regarding the impact of faith in leaving, support of the congregation, community resources,and clergy as counselors. The clergy's survey had the same questions, plus open-ended questions about their skills in counseling victims, their congregation's support for victims, community resources, and beliefs that could impact a victim's choice in leaving. Data were analyzed using descriptive statistics, simple frequencies, and bivariate correlations. Narrative data were analyzed using content analysis. The results of this study indicated that change is slow. Members want their clergy to become more educated in counseling and in speaking about domestic violence from the pulpit. Clergy felt comfortable in making referrals for professional counseling, while the majority of members would prefer counseling with their pastor if they were in a violent relationship. Both clergy and members want to create a safe and supportive environment for victims/survivors of violent relationships. Findings from this study exemplify the need for pastors to remove the silence about domestic violence in their congregations and address the misunderstood social religious beliefs that may bind a victim to the violence.

Faith in Their Futures: The Youth and Congregations in Partnership Program of the Kings County (Brooklyn, NY) District Attorney's Office. National Faith-Based Initiative Field Report Series

ERIC Educational Resources Information Center

Blank, Susan; Davie, Fred

2004-01-01

Why would a law-and-order district attorney in one of the toughest, most crime-prone areas in the nation develop a faith-based alternative to incarceration for youthful offenders? District Attorney Charles J. Hynes credits his faith and a strong conviction that society can't prison-build its way out of the crime problem. Hynes established Youth…

76 FR 70472 - Notice of Submission of Proposed Information Collection to OMB Congregate Housing Services Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-14

...The proposed information collection requirement described below has been submitted to the Office of Management and Budget (OMB) for review, as required by the Paperwork Reduction Act. The Department is soliciting public comments on the subject proposal. This information is necessary to monitor the use of grant funds for the Congregate Housing Services Program (CHSP) according to statutory, regulatory, and administrative requirements.

Great III - Cultural Resource Inventory. Volume 2

DTIC Science & Technology

1982-05-01

60 p., illus. Articles on Lorimier, Cape Rock, New Madrid Earthquakes , Old Bethel Church , McKendree Chapel. -216- ’fc-«wwwB««B^jt.ijafci.^.*Ji...Program. March 30, 1930, 6 p., illustrated. Brief history of congregation. Dedicating new church . Includes photographs. Historical Association of Greater...Hanover Lutheran Church , 1846-1946. 1946 Cape Glrardeau, Missouri, 1946. 24 p., illustrated. Congregation originated 1846. Built new struc- ture in

The emotional impact of fundamentalist religious participation: an empirical study of intragroup variation.

PubMed

Ness, Robert C; Wintrob, Ronald M

1980-04-01

The relationship between religious activity within a Pentecostal congregation and the emotional status of the congregants is described. Data derived from a field study conducted in a Newfoundland coastal community. The more frequently people engaged in religious activities, the less likely they were to report symptoms of emotional distress. Significant within-group variation was found in terms of the frequency and type of religious activity.

The board's role in meaningful collaboration. After negotiations are completed, a new round of work begins.

PubMed

Deets, M K

1991-06-01

For collaborations that in some way modify involved organizations' assets and organizational or governance issues, negotiations are the responsibility of the congregation and not the healthcare system. Congregational leaders should, however, actively involve the system chief executive officer in the process and should also seek the advice of the system board. The board can be particularly helpful in offering financial, legal, and managerial advice to negotiators. Once an agreement is reached, however, the board must consider whether to approve it. And from this point forward, its involvement in the details of the collaboration will be more active. Because board members must evaluate a proposed collaboration from the perspective of the organization they serve, they may not always take the same view of it as did the congregational leaders. Moreover, what congregational leaders believe to be in the best interests of Catholic healthcare may not be consistent with the legitimate self-interest of some of the many constituencies affected by a collaboration. After negotiators have reached an agreement and the board has approved it, the board must make the necessary financial and organizational changes necessary to achieve the transition to a new corporate entity. In doing so, its goal will be to promote standardization without destroying the member institutions' rich traditions.

Targeting BRCAness in Gastric Cancer

DTIC Science & Technology

2017-10-01

inhibitors. We also generated a modified CRISPR system using dCas9-KRAB expressing variants of these cells, and validated them for CRISPRi screening...Figure 2. Validation of CRISPR activity following transduction with sgRNAs targeting CD55 and FACS staining with the anti-CD55 antibody. Data shown...interpretation of CRISPR experiments Morgan Diolaiti Specialist UCSF PH.D. Experimental planning and reporting Jefferson Woods SRA UCSF B.S. Perform drug

Characterization of the newly isolated ω-oxidizing yeast Candida sorbophila DS02 and its potential applications in long-chain dicarboxylic acid production.

PubMed

Lee, Heeseok; Sugiharto, Yohanes Eko Chandra; Lee, Seunghoon; Park, Gyuyeon; Han, Changpyo; Jang, Hyeran; Jeon, Wooyoung; Park, Heejoon; Ahn, Jungoh; Kang, Kyungbo; Lee, Hongwoen

2017-08-01

α, ω-Dicarboxylic acids (DCAs) are multipurpose chemicals widely used in polymers, perfumes, plasticizers, lubricants, and adhesives. The biotransformation of DCAs from alkanes and fatty acids by microorganisms has attracted recent interest, since synthesis via chemical oxidation causes problems in terms of the environment and safety. We isolated an ω-oxidizing yeast from a wastewater disposal facility of a petrochemical factory by chemostat enrichment culture. The haploid strain identified as Candida sorbophila DS02 grew on glucose and dodecane, exhibiting greater cell shrinkage on the latter. In flask cultures with mixed alkanes (C10-16) and fatty acid methyl esters (C10-16), DS02 used mixed alkanes simultaneously unlike Candida tropicalis and Yarrowia lipolytica and showed high substrate resistance. In flask cultures with acrylic acid-a known inhibitor of β-oxidation-DS02 produced 0.28 g/l dodecanedioic acid (DDDA) from dodecane, similar to wild-type C. tropicalis ATCC 20336. In fed-batch fermentation, DS02 produced 9.87 g/l DDDA, which was 5.7-fold higher than wild-type C. tropicalis. These results suggest that C. sorbophila strain DS02 has potential applications for the large-scale production of DCA.

Efficient targeted DNA methylation with chimeric dCas9–Dnmt3a–Dnmt3L methyltransferase

PubMed Central

Stepper, Peter; Kungulovski, Goran; Jurkowska, Renata Z.; Chandra, Tamir; Krueger, Felix; Reinhardt, Richard

2017-01-01

Abstract DNA methylation plays a critical role in the regulation and maintenance of cell-type specific transcriptional programs. Targeted epigenome editing is an emerging technology to specifically regulate cellular gene expression in order to modulate cell phenotypes or dissect the epigenetic mechanisms involved in their control. In this work, we employed a DNA methyltransferase Dnmt3a–Dnmt3L construct fused to the nuclease-inactivated dCas9 programmable targeting domain to introduce DNA methylation into the human genome specifically at the EpCAM, CXCR4 and TFRC gene promoters. We show that targeting of these loci with single gRNAs leads to efficient and widespread methylation of the promoters. Multiplexing of several guide RNAs does not increase the efficiency of methylation. Peaks of targeted methylation were observed around 25 bp upstream and 40 bp downstream of the PAM site, while 20–30 bp of the binding site itself are protected against methylation. Potent methylation is dependent on the multimerization of Dnmt3a/Dnmt3L complexes on the DNA. Furthermore, the introduced methylation causes transcriptional repression of the targeted genes. These new programmable epigenetic editors allow unprecedented control of the DNA methylation status in cells and will lead to further advances in the understanding of epigenetic signaling. PMID:27899645

Community coverage in a rural, church-based, hypertension screening program in Edgecombe County, North Carolina.

PubMed Central

Strogatz, D S; James, S A; Elliott, D; Ramsey, D; Cutchin, L M; Ibrahim, M A

1985-01-01

In a rural, church-based hypertension program in Edgecombe County, North Carolina, screening of the congregations was complemented by a community outreach component targeted at 18-60 year old males, a group at higher risk for untreated hypertension. Compared with its estimated frequency in the community, untreated hypertension was as common in the church congregations and somewhat less prevalent than expected among outreach screenees. PMID:3976968

Acceptable Risk? The Nuclear Age in the United States. Study/Action Guide [and] Companion to Study/Action Guide for Congregations and Religious Groups.

ERIC Educational Resources Information Center

American Friends Service Committee, Philadelphia, PA. National Action/Research on the Military Industrial Complex.

A study-action guide and a companion guide are intended to help citizens explore some of the challenging dilemmas of U.S. nuclear policy. The two guides place strong emphasis on group discussion and participation as well as action citizens might want to take to bring about a non-nuclear world. The companion guide is intended for congregations and…

Central Mechanisms and Treatment of Blast Induced Auditory and Vestibular Injuries

DTIC Science & Technology

2017-01-01

which p21 CRISPR /dCas9 Lentiviral activation particles were transfected to the cultured primary cortical neurons. The preliminary data showed a...were down-regulated by knockout p21Cip1 in which p21 CRISPR /Cas9 was transfected to the cultured primary neurons (Fig. 9). These combined results...regions; CRISPR /Cas9 gene editing and Single cell RNA-seq assay Pathology: silver staining, immunohistochemistry on transgenic mice for specific

Age-specific olfactory attraction between Western honey bee drones (Apis mellifera) and its chemical basis.

PubMed

Bastin, Florian; Savarit, Fabrice; Lafon, Grégory; Sandoz, Jean-Christophe

2017-01-01

During the mating season, drones (males) of the Western honey bee (Apis mellifera) form congregations numbering thousands high in the air. Virgin queens arrive at these congregations after they have formed and mate on the fly with 15-20 drones. To explain the formation of drone congregations, a drone-produced aggregation pheromone has been proposed many years ago but due to the low accessibility of natural mating sites in bees, its study has progressed slowly. Recently, we used a walking simulator in controlled laboratory conditions to show that drones are indeed attracted by groups of other drones. Since these previous experiments were carried out with drones captured when flying out of the hive, it is currently unclear if this olfactory attraction behaviour is related to the drones' sexual maturity (usually reached between 9 and 12 days) and may thus be indicative of a possible role in congregation formation, or if it is observed at any age and may represent in-hive aggregation. We thus assessed here the dependency of drone olfactory attraction on their age. First, we performed behavioural experiments in the walking simulator to measure olfactory preferences of drones in three age groups from 2-3 to 12-15 days. Then, we performed chemical analyses in the same age groups to evaluate whether chemical substances produced by the drones may explain age differences in olfactory attraction. We show that honey bee drones are attracted by conspecifics of the same age when they are sexually mature (12-15 days old) but not when they are younger (2-3 and 7-8 days old). In parallel, our data show that drones' chemical profile changes with age, including its most volatile fraction. These results are discussed in the context of drone mutual attraction both within the hive and at drone congregations.

Age-specific olfactory attraction between Western honey bee drones (Apis mellifera) and its chemical basis

PubMed Central

Bastin, Florian; Savarit, Fabrice; Lafon, Grégory

2017-01-01

During the mating season, drones (males) of the Western honey bee (Apis mellifera) form congregations numbering thousands high in the air. Virgin queens arrive at these congregations after they have formed and mate on the fly with 15-20 drones. To explain the formation of drone congregations, a drone-produced aggregation pheromone has been proposed many years ago but due to the low accessibility of natural mating sites in bees, its study has progressed slowly. Recently, we used a walking simulator in controlled laboratory conditions to show that drones are indeed attracted by groups of other drones. Since these previous experiments were carried out with drones captured when flying out of the hive, it is currently unclear if this olfactory attraction behaviour is related to the drones’ sexual maturity (usually reached between 9 and 12 days) and may thus be indicative of a possible role in congregation formation, or if it is observed at any age and may represent in-hive aggregation. We thus assessed here the dependency of drone olfactory attraction on their age. First, we performed behavioural experiments in the walking simulator to measure olfactory preferences of drones in three age groups from 2-3 to 12-15 days. Then, we performed chemical analyses in the same age groups to evaluate whether chemical substances produced by the drones may explain age differences in olfactory attraction. We show that honey bee drones are attracted by conspecifics of the same age when they are sexually mature (12-15 days old) but not when they are younger (2-3 and 7-8 days old). In parallel, our data show that drones’ chemical profile changes with age, including its most volatile fraction. These results are discussed in the context of drone mutual attraction both within the hive and at drone congregations. PMID:28977020

MtDNA COI-COII marker and drone congregation area: an efficient method to establish and monitor honeybee (Apis mellifera L.) conservation centres.

PubMed

Bertrand, Bénédicte; Alburaki, Mohamed; Legout, Hélène; Moulin, Sibyle; Mougel, Florence; Garnery, Lionel

2015-05-01

Honeybee subspecies have been affected by human activities in Europe over the past few decades. One such example is the importation of nonlocal subspecies of bees which has had an adverse impact on the geographical repartition and subsequently on the genetic diversity of the black honeybee Apis mellifera mellifera. To restore the original diversity of this local honeybee subspecies, different conservation centres were set up in Europe. In this study, we established a black honeybee conservation centre Conservatoire de l'Abeille Noire d'Ile de France (CANIF) in the region of Ile-de-France, France. CANIF's honeybee colonies were intensively studied over a 3-year period. This study included a drone congregation area (DCA) located in the conservation centre. MtDNA COI-COII marker was used to evaluate the genetic diversity of CANIF's honeybee populations and the drones found and collected from the DCA. The same marker (mtDNA) was used to estimate the interactions and the haplotype frequency between CANIF's honeybee populations and 10 surrounding honeybee apiaries located outside of the CANIF. Our results indicate that the colonies of the conservation centre and the drones of the DCA show similar stable profiles compared to the surrounding populations with lower level of introgression. The mtDNA marker used on both DCA and colonies of the conservation centre seems to be an efficient approach to monitor and maintain the genetic diversity of the protected honeybee populations. © 2014 John Wiley & Sons Ltd.

DOD Financial Management: Actions Are Needed on Audit Issues Related to the Marine Corps 2012 Schedule of Budgetary Activity

DTIC Science & Technology

2015-07-01

Requisitioning and Issue Procedures OIG Office of Inspector General OMB Office of Management and Budget QMD Quantitative Methods Division SABRS ...Reporting System ( SABRS )—and transactions recorded in the current year may be improperly recorded to appropriations not included in the Marine Corps...Accountability System (DCAS)55 to the Marine Corps’ SABRS general ledger system and through the Defense Departmental Reporting Systems (DDRS) to financial

Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage

PubMed Central

Josephs, Eric A.; Kocak, D. Dewran; Fitzgibbon, Christopher J.; McMenemy, Joshua; Gersbach, Charles A.; Marszalek, Piotr E.

2015-01-01

CRISPR-associated endonuclease Cas9 cuts DNA at variable target sites designated by a Cas9-bound RNA molecule. Cas9's ability to be directed by single ‘guide RNA’ molecules to target nearly any sequence has been recently exploited for a number of emerging biological and medical applications. Therefore, understanding the nature of Cas9's off-target activity is of paramount importance for its practical use. Using atomic force microscopy (AFM), we directly resolve individual Cas9 and nuclease-inactive dCas9 proteins as they bind along engineered DNA substrates. High-resolution imaging allows us to determine their relative propensities to bind with different guide RNA variants to targeted or off-target sequences. Mapping the structural properties of Cas9 and dCas9 to their respective binding sites reveals a progressive conformational transformation at DNA sites with increasing sequence similarity to its target. With kinetic Monte Carlo (KMC) simulations, these results provide evidence of a ‘conformational gating’ mechanism driven by the interactions between the guide RNA and the 14th–17th nucleotide region of the targeted DNA, the stabilities of which we find correlate significantly with reported off-target cleavage rates. KMC simulations also reveal potential methodologies to engineer guide RNA sequences with improved specificity by considering the invasion of guide RNAs into targeted DNA duplex. PMID:26384421

Repurposing the CRISPR-Cas9 system for targeted DNA methylation.

PubMed

Vojta, Aleksandar; Dobrinić, Paula; Tadić, Vanja; Bočkor, Luka; Korać, Petra; Julg, Boris; Klasić, Marija; Zoldoš, Vlatka

2016-07-08

Epigenetic studies relied so far on correlations between epigenetic marks and gene expression pattern. Technologies developed for epigenome editing now enable direct study of functional relevance of precise epigenetic modifications and gene regulation. The reversible nature of epigenetic modifications, including DNA methylation, has been already exploited in cancer therapy for remodeling the aberrant epigenetic landscape. However, this was achieved non-selectively using epigenetic inhibitors. Epigenetic editing at specific loci represents a novel approach that might selectively and heritably alter gene expression. Here, we developed a CRISPR-Cas9-based tool for specific DNA methylation consisting of deactivated Cas9 (dCas9) nuclease and catalytic domain of the DNA methyltransferase DNMT3A targeted by co-expression of a guide RNA to any 20 bp DNA sequence followed by the NGG trinucleotide. We demonstrated targeted CpG methylation in a ∼35 bp wide region by the fusion protein. We also showed that multiple guide RNAs could target the dCas9-DNMT3A construct to multiple adjacent sites, which enabled methylation of a larger part of the promoter. DNA methylation activity was specific for the targeted region and heritable across mitotic divisions. Finally, we demonstrated that directed DNA methylation of a wider promoter region of the target loci IL6ST and BACH2 decreased their expression. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

PubMed

Stepper, Peter; Kungulovski, Goran; Jurkowska, Renata Z; Chandra, Tamir; Krueger, Felix; Reinhardt, Richard; Reik, Wolf; Jeltsch, Albert; Jurkowski, Tomasz P

2017-02-28

DNA methylation plays a critical role in the regulation and maintenance of cell-type specific transcriptional programs. Targeted epigenome editing is an emerging technology to specifically regulate cellular gene expression in order to modulate cell phenotypes or dissect the epigenetic mechanisms involved in their control. In this work, we employed a DNA methyltransferase Dnmt3a-Dnmt3L construct fused to the nuclease-inactivated dCas9 programmable targeting domain to introduce DNA methylation into the human genome specifically at the EpCAM, CXCR4 and TFRC gene promoters. We show that targeting of these loci with single gRNAs leads to efficient and widespread methylation of the promoters. Multiplexing of several guide RNAs does not increase the efficiency of methylation. Peaks of targeted methylation were observed around 25 bp upstream and 40 bp downstream of the PAM site, while 20-30 bp of the binding site itself are protected against methylation. Potent methylation is dependent on the multimerization of Dnmt3a/Dnmt3L complexes on the DNA. Furthermore, the introduced methylation causes transcriptional repression of the targeted genes. These new programmable epigenetic editors allow unprecedented control of the DNA methylation status in cells and will lead to further advances in the understanding of epigenetic signaling. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

"It's Kind of a Dichotomy": Thoughts Related to Calling and Purpose from Pastors Working and Counseling in Urban Resource-Poor Communities.

PubMed

Payne, Jennifer Shepard

2017-08-01

Pastors serving low-income urban areas are first-responders to emotional issues by default, since fewer mental health resources are available. Thus, it is important to understand how pastors serving urban resource-poor areas reflect on their counseling role. Forty-eight Black, Hispanic, and White pastors with urban congregations in Los Angeles or Chicago reflect on their pastoral calling and its relation to their counseling role. Through phenomenology, the pastors' lived experiences as they counseled in an urban context were explored. Analysis revealed complex feelings about their counseling role in light of their resource-poor environments. Recommendations are provided based on the findings.

Factor Structure of the Brief Multidimensional Measure of Religiousness/Spirituality in US and Indian Samples with Traumatic Brain Injury.

PubMed

Johnstone, Brick; Bhushan, Braj; Hanks, Robin; Yoon, Dong Pil; Cohen, Daniel

2016-04-01

The aim of this paper was to determine the factor structure of the Brief Multidimensional Measure of Religiousness/Spirituality (BMMRS) based on a sample of individuals from diverse cultures (i.e., USA, India), ethnicities (i.e., Caucasian, African-American, South Asian), and religions (i.e., Christian, Muslim, Hindu). A total of 109 individuals with traumatic brain injury (TBI) were included. Participants completed the BMMRS as part of a broader study on spirituality, religion, prosocial behaviors, and neuropsychological function. A principal components factor analysis with varimax rotation and Kaiser normalization identified a six-factor solution accounting for 72% of the variance in scores. Five of the factors were deemed to be interpretable and were labeled based on face validity as: (1) Positive Spirituality/Religious Practices; (2) Positive Congregational Support; (3) Negative Spirituality/Negative Congregational Support; (4) Organizational Religion; and (5) Forgiveness. The results were generally consistent with previous studies, suggesting the existence of universal religious, spiritual, and congregational support factors across different cultures and faith traditions. For health outcomes research, it is suggested that the BMMRS factors may be best conceptualized as measuring the following general domains: (a) emotional connectedness with a higher power (i.e., spirituality, positive/negative); (b) culturally based behavioral practices (i.e., religion); and (c) social support (i.e., positive/negative). The results indicate that factor relationships may differ among spiritual, religious, and congregational support variables according to culture and/or religious tradition.

An Outline of Biological Hazards to Swimmers in Tropical and Subtropical Waters,

DTIC Science & Technology

1965-08-01

section, there will be considered hazards from shores, beaches , and river banks. In these areas, animals and insects tend to gather , and it might be...remembered that some insects , etc., congregate arou nd water. Thu s one may be bitten by a tsetse fl y in the sun, or a mosquito in the shade, at any time...massive exposure.) Insect repellents are useful , but they wash off and are not very effective when emerging after havi ng been in the water for a while

[The fight of the communist authorities with the Catholic Church in the health service in Poland (1945-1970)].

PubMed

Jastrzebowski, Zbigniew

2005-01-01

The article shows the process of nationalization of Polish hospitals run by religious congregations and elimination of priests runs from medical care. The process lasted until resignation of Władysław Gomułka from the post of the first secretary of the Polish United Worker's Party. We can distinguish two periods of the process: 1948-1953 of nationalized of the congregation hospitals and 1960 - 1970 when this presence of the Catholic Church in the health was limited to indispensable minimum.

The GoodNEWS (Genes, Nutrition, Exercise, Wellness, and Spiritual Growth) Trial: a community-based participatory research (CBPR) trial with African-American church congregations for reducing cardiovascular disease risk factors--recruitment, measurement, and randomization.

PubMed

DeHaven, Mark J; Ramos-Roman, Maria A; Gimpel, Nora; Carson, JoAnn; DeLemos, James; Pickens, Sue; Simmons, Chris; Powell-Wiley, Tiffany; Banks-Richard, Kamakki; Shuval, Kerem; Duvahl, Julie; Duval, Julie; Tong, Liyue; Hsieh, Natalie; Lee, Jenny J

2011-09-01

Although cardiovascular diseases (CVD) are the leading cause of death among Americans, significant disparities persist in CVD prevalence, morbidity, and mortality based on race and ethnicity. However, few studies have examined risk factor reduction among the poor and ethnic minorities. Community-based participatory research (CBPR) study using a cluster randomized design--African-American church congregations are the units of randomization and individuals within the congregations are the units of analysis. Outcome variables include dietary change (Diet History Questionnaire), level of physical activity (7-Day Physical Activity Recall), lipoprotein levels, blood pressure, fasting glucose, and hemoglobin A1c. Eighteen (18) church congregations were randomized to either a health maintenance intervention or a control condition. Complete data were obtained on 392 African-American individuals, 18 to 70 years of age, predominantly employed women with more than a high school diploma. Treatment and intervention groups were similar at baseline on saturated fat intake, metabolic equivalent of tasks (METS) per day, and other risk factors for CVD. The GoodNEWS trial successfully recruited and evaluated CVD-related risk among African-American participants using a CBPR approach. Several logistical challenges resulted in extending the recruitment, preliminary training, and measurement periods. The challenges were overcome with the assistance of a local community consultant and a professional event planner. Our experience supports the need for incorporating non-traditional community-based staff into the design and operational plan of CBPR trials. Copyright © 2011 Elsevier Inc. All rights reserved.

Connecting congregations: technology resources influence parish nurse practice.

PubMed

Zerull, Lisa M; Near, Kelly K; Ragon, Bart; Farrell, Sarah P

2009-01-01

This descriptive pilot study evaluated the influence of health resource information education and the use of Web-based communication technology on the professional practice of the parish nurse in the congregational setting. Five parish nurse participants from varied denominations in rural and nonrural Virginia received a laptop computer, printer, video projector, and webcam along with high-speed Internet access in each congregational setting. The nurses attended two group education sessions that incorporated computer applications and training in accessing and using quality health information resources and communication applications such as a group "chat" software and webcam to communicate with others through high-speed Internet access. Qualitative analysis from semistructured interviews of nurses confirmed that participants found the project to be beneficial in terms of awareness, education, and applicability of technology use in parish nurse practice. Quantitative data from preproject and postproject surveys found significant differences in nurses' abilities and confidence with technology use and application. Findings showed that the knowledge and experience gained from this study enhanced parish nurse practice and confidence in using technology for communication, health education, and counseling.

Empower multiplex cell and tissue-specific CRISPR-mediated gene manipulation with self-cleaving ribozymes and tRNA.

PubMed

Xu, Li; Zhao, Lixia; Gao, Yandi; Xu, Jing; Han, Renzhi

2017-03-17

Clustered regularly interspaced short palindromic repeat/Cas9 (CRISPR/Cas9) system has emerged in recent years as a highly efficient RNA-guided gene manipulation platform. Simultaneous editing or transcriptional activation/suppression of different genes becomes feasible with the co-delivery of multiple guide RNAs (gRNAs). Here, we report that multiple gRNAs linked with self-cleaving ribozymes and/or tRNA could be simultaneously expressed from a single U6 promoter to exert genome editing of dystrophin and myosin binding protein C3 in human and mouse cells. Moreover, this strategy allows the expression of multiple gRNAs for synergistic transcription activation of follistatin when used with catalytically inactive dCas9-VP64 or dCas9-p300core fusions. Finally, the gRNAs linked by the self-cleaving ribozymes and tRNA could be expressed from RNA polymerase type II (pol II) promoters such as generic CMV and muscle/heart-specific MHCK7. This is particularly useful for in vivo applications when the packaging capacity of recombinant adeno-associated virus is limited while tissue-specific delivery of gRNAs and Cas9 is desired. Taken together, this study provides a novel strategy to enable tissue-specific expression of more than one gRNAs for multiplex gene editing from a single pol II promoter. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation

PubMed Central

Farasat, Iman; Salis, Howard M.

2016-01-01

The ability to precisely modify genomes and regulate specific genes will greatly accelerate several medical and engineering applications. The CRISPR/Cas9 (Type II) system binds and cuts DNA using guide RNAs, though the variables that control its on-target and off-target activity remain poorly characterized. Here, we develop and parameterize a system-wide biophysical model of Cas9-based genome editing and gene regulation to predict how changing guide RNA sequences, DNA superhelical densities, Cas9 and crRNA expression levels, organisms and growth conditions, and experimental conditions collectively control the dynamics of dCas9-based binding and Cas9-based cleavage at all DNA sites with both canonical and non-canonical PAMs. We combine statistical thermodynamics and kinetics to model Cas9:crRNA complex formation, diffusion, site selection, reversible R-loop formation, and cleavage, using large amounts of structural, biochemical, expression, and next-generation sequencing data to determine kinetic parameters and develop free energy models. Our results identify DNA supercoiling as a novel mechanism controlling Cas9 binding. Using the model, we predict Cas9 off-target binding frequencies across the lambdaphage and human genomes, and explain why Cas9’s off-target activity can be so high. With this improved understanding, we propose several rules for designing experiments for minimizing off-target activity. We also discuss the implications for engineering dCas9-based genetic circuits. PMID:26824432

Development and evaluation of a bible college-based course on faith and health.

PubMed

Pichert, James W; McClellan, Linda H; Larson, Celia; Kenerson, Donna; Brown, Anne; Reid, Ron; Miller, Stephania; Hargreaves, Margaret

2006-01-01

Research supports the potential effectiveness of health programs offered through African American churches, but pastors are often unprepared to assess the value of and help their congregations adopt such programs. This article summarizes how Nashville REACH 2010 addressed these issues via a "Faith and Health" course offered by the American Baptist College, a 4-year coeducational, liberal arts Bible college serving a predominantly African American student body. Participants became change agents by planning health-related programs for their congregations. Content analysis of student projects revealed 5 themes deemed important for program implementation and instituting systems change.

[Managment in nursing and the administration of third sector organizations].

PubMed

Ruthes, Rosa Maria; Cunha, Isabel Cristina Kowal Olm

2006-01-01

In this article of bibliographical revision it was aimed at verifying the evolution of the third sector and the relations between nursing management in that organizations. It is observed a growing of this sector in health area, bringing a market anplification in the work of the nurse. Thus, it is considered the need for warning the nurses to be prepared for the management in these organizations, seeking for development in hospital management. Third sector is being valued as a form of social promotion in the health, education, social assistance and others segments, congregating individuals and institutions in a participative form.

Shewanella oneidensis MR-1 chemotaxis proteins and electron-transport chain components essential for congregation near insoluble electron acceptors.

PubMed

Harris, H Wayne; El-Naggar, Mohamed Y; Nealson, Kenneth H

2012-12-01

Shewanella oneidensis MR-1 cells utilize a behaviour response called electrokinesis to increase their speed in the vicinity of IEAs (insoluble electron acceptors), including manganese oxides, iron oxides and poised electrodes [Harris, El-Naggar, Bretschger, Ward, Romine, Obraztsova and Nealson (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 326-331]. However, it is not currently understood how bacteria remain in the vicinity of the IEA and accumulate both on the surface and in the surrounding medium. In the present paper, we provide results indicating that cells that have contacted the IEAs swim faster than those that have not recently made contact. In addition, fast-swimming cells exhibit an enhancement of swimming reversals leading to rapid non-random accumulation of cells on, and adjacent to, mineral particles. We call the observed accumulation near IEAs 'congregation'. Congregation is eliminated by the loss of a critical gene involved with EET (extracellular electron transport) (cymA, SO_4591) and is altered or eliminated in several deletion mutants of homologues of genes that are involved with chemotaxis or energy taxis in Escherichia coli. These genes include chemotactic signal transduction protein (cheA-3, SO_3207), methyl-accepting chemotaxis proteins with the Cache domain (mcp_cache, SO_2240) or the PAS (Per/Arnt/Sim) domain (mcp_pas, SO_1385). In the present paper, we report studies of S. oneidensis MR-1 that lend some insight into how microbes in this group can 'sense' the presence of a solid substrate such as a mineral surface, and maintain themselves in the vicinity of the mineral (i.e. via congregation), which may ultimately lead to attachment and biofilm formation.

History of DCAS 1961. Volume V. Origins of the USAF Space Program 1945-1956

DTIC Science & Technology

1961-01-01

AVAILABILITY CODES N! _______________ PHOTOGRAPH TIS SHEET AND RETURN TO DTIC-DDA-2 FORM DOCUMENT PROCESSING SHEE~~DTIC OC 970A OCT 79 AFSC HISTORICAL I...IZ ION OR HIGHER A THO ITY IN T E DI ECT LI COMMAN SIi Prepredundr te poviion ofAirFore Rgultio 21-1 nd ir ori i Sytem ComandSuplemnt N. Itheetoas...information as it appears in the narrative. It is to be hoped that additional information bearing on the formative years of the space program will appear as a

Assessment of HIV/AIDS prevention of rural African American Baptist leaders: implications for effective partnerships for capacity building in American communities.

PubMed

Foster, Pamela Payne; Cooper, Krista; Parton, Jason M; Meeks, John O

2011-04-01

This exploratory study sought to elicit information from rural Baptist leaders about their interest in HIV prevention activities within their congregation and other influencers in their human deficiency virus (HIV) prevention activities based on their geographical residence (urban vs rural). This study utilized both qualitative (in-depth interviews, N = 8) and quantitative (written survey, N = 56) methodologies (mixed method) in order to obtain pertinent information. A ministerial liaison was hired to assist in recruitment of participants within a statewide Baptist conference. Written surveys were distributed at a statewide meeting. The majority of participants (N = 50) in this study (89.3%) were receptive to conducting HIV/AIDS prevention activities within their congregations. The study also revealed rural/urban differences, including: interest in HIV/AIDS prevention, direct experiences with infected persons, or whether churches have a health-related ministry. Positive influencers of HIV/AIDS prevention in rural church leaders included either the participant or their spouse being in a health-related occupation, migratory patterns from larger metropolitan areas in other areas of the country to the rural south, and whether the church has a health-related ministry. Findings from this study are significant for a variety of reasons, including use of faith-based models for HIV/ AIDS capacity building and use of potential influencers on HIV/AIDS prevention in African Americans in the rural Deep South, where the epidemic is growing fastest. Future implications of this study might include expansion of faith-based models to include other denominations and health care providers as well of use of positive influencers to develop future HIV/AIDS intervention strategies.

Nemesis revisited: tuberculosis infection in a New York City men's shelter.

PubMed Central

Paul, E A; Lebowitz, S M; Moore, R E; Hoven, C W; Bennett, B A; Chen, A

1993-01-01

In November 1990, a screening was conducted to determine the point prevalence of tuberculosis infection in a volunteer sample of homeless men (n = 161) living in a congregate shelter in New York City. Of those for whom we have results (n = 134), 79% were positive for tuberculosis. The mean length of shelter stay from date of shelter entry was 31.8 months and was significantly associated with the tuberculosis infection rate. The findings suggest that crowded living conditions and the presence of a stable resident pool in crowded congregate shelters may be associated with transmission of tuberculosis infection. Images p1744-a PMID:8259807

"In the storminess": multi-disciplinary approaches to scriptural images representing ethical challenges in the pastor-congregant relationship.

PubMed

O'Connor, Thomas St James; Walsh-Bowers, Richard; Psychology, Community; Ross, Christopher; Sawchuk, Dana; Hatzipantelis, Maria

2006-01-01

In this qualitative study the authors examine the Scriptural images that 10 Lutheran pastors employed in describing the ethical challenges in the pastor-congregant relationship. The analysis of Scriptural images is part of a larger study on pastors' experiences of a mandatory workshop, "Crossing the Boundaries (CTB),"which is required of Evangelical Lutheran Church in Canada (ELCIC) seminarians. The pastors' images were analyzed from the four perspectives of depth psychology, theology, social ethics, and sociology. In commenting on tensions in the pastors' Scriptural images the authors note commonalities among the four theoretical perspectives and discuss implications for practice and future research.

Genetic structure of nest aggregations and drone congregations of the southeast Asian stingless bee Trigona collina.

PubMed

Cameron, E C; Franck, P; Oldroyd, B P

2004-08-01

In stingless bees, sex is determined by a single complementary sex-determining locus. This method of sex determination imposes a severe cost of inbreeding because an egg fertilized by sperm carrying the same sex allele as the egg results in a sterile diploid male. To explore how reproductive strategies may be used to avoid inbreeding in stingless bees, we studied the genetic structure of a population of 27 colonies and three drone congregations of Trigona collina in Chanthaburi, Thailand. The colonies were distributed across six nest aggregations, each aggregation located in the base of a different fig tree. Genetic analysis at eight microsatellite loci showed that colonies within aggregations were not related. Samples taken from three drone congregations showed that the males were drawn from a large number of colonies (estimated to be 132 different colonies in our largest swarm). No drone had a genotype indicating that it could have originated from the colony that it was directly outside. Combined, these results suggest that movements of drones and possibly movements of reproductive swarms among colony aggregations provide two mechanisms of inbreeding avoidance. Copyright 2004 Blackwell Publishing Ltd

Contextualizing and assessing the social capital of seniors in congregate housing residences: study design and methods

PubMed Central

Moore, Spencer; Shiell, Alan; Haines, Valerie; Riley, Therese; Collier, Carrie

2005-01-01

Background This article discusses the study design and methods used to contextualize and assess the social capital of seniors living in congregate housing residences in Calgary, Alberta. The project is being funded as a pilot project under the Institute of Aging, Canadian Institutes for Health Research. Design/Methods Working with seniors living in 5 congregate housing residencies in Calgary, the project uses a mixed method approach to develop grounded measures of the social capital of seniors. The project integrates both qualitative and quantitative methods in a 3-phase research design: 1) qualitative, 2) quantitative, and 3) qualitative. Phase 1 uses gender-specific focus groups; phase 2 involves the administration of individual surveys that include a social network module; and phase 3 uses anamolous-case interviews. Not only does the study design allow us to develop grounded measures of social capital but it also permits us to test how well the three methods work separately, and how well they fit together to achieve project goals. This article describes the selection of the study population, the multiple methods used in the research and a brief discussion of our conceptualization and measurement of social capital. PMID:15836784

Predictors of HIV/AIDS Programming in African American Churches: Implications for Prevention, Testing and Care

PubMed Central

Stewart, Jennifer M.; Hanlon, Alexandra; Brawner, Bridgette M.

2017-01-01

Using data from the National Congregational Study, we examined predictors of having a HIV/AIDS program in predominately African American churches across the United States. We conducted regression analyses of Wave II data (N = 1,506) isolating the sample to churches with a predominately African American membership. The dependent variable asked whether or not the congregation currently had any program focused on HIV or AIDS. Independent variables included several variables from the individual, organizational, and social levels. Our study revealed that region, clergy age, congregant disclosure of HIV-positive status, permitting cohabiting couples to be members, sponsorship or participation in programs targeted to physical health issues and having a designated person or committee to address health-focused programs significantly increased the likelihood of African American churches having a HIV/AIDS program. A paucity of nationally representative research focuses on the social, organizational and individual level predictors of having HIV/AIDS programs in African American churches. Determining the characteristics of churches with HIV/AIDS programming at multiple levels is a critical and necessary approach with significant implications for partnering with African American churches in HIV initiatives. PMID:27540035

Ethical Challenges of Personal Disclosure in Gaining Entry with Religious Congregations.

PubMed

Todd, Nathan R

2017-12-01

This is a story about learning how to navigate my social identities as a non-religious gay man attempting to conduct data-based consultation with a religious congregation. Beyond my own growth in knowing myself better, this story speaks to the larger ethical challenge of how we build trust in community relationships, and in particular how much of our personal selves we need to disclose in the process of an individual or group deciding to work with us. Individuals and groups make decisions to work with us based on who they perceive us to be; thus, what is our ethical obligation to disclose aspects of who we are to promote full informed consent? To illustrate this ethical challenge of personal disclosure, I tell the story of discussions I had with three different religious leaders and a congregational committee about potentially working together. Throughout these stories, I reflect on my own messy process of growth as a window into the more general question of how we navigate our identities and values as community psychologists in the work we do with communities. © Society for Community Research and Action 2017.

The role of religious leaders in promoting healthy habits in religious institutions.

PubMed

Anshel, Mark H; Smith, Mitchell

2014-08-01

The growing obesity epidemic in the West, in general, and the U.S.A., in particular, is resulting in deteriorating health, premature and avoidable onset of disease, and excessive health care costs. The religious community is not immune to these societal conditions. Changing health behavior in the community requires both input from individuals who possess knowledge and credibility and a receptive audience. One group of individuals who may be uniquely positioned to promote community change but have been virtually ignored in the applied health and consulting psychology literature is religious leaders. These individuals possess extraordinary credibility and influence in promoting healthy behaviors by virtue of their association with time-honored religious traditions and the status which this affords them-as well as their communication skills, powers of persuasion, a weekly (captive) audience, mastery over religious texts that espouse the virtues of healthy living, and the ability to anchor health-related actions and rituals in a person's values and spirituality. This article focuses on ways in which religious leaders might promote healthy habits among their congregants. By addressing matters of health, nutrition, and fitness from the pulpit and in congregational programs, as well as by visibly adopting the tenets of a healthier lifestyle, clergy can deliver an important message regarding the need for healthy living. Through such actions, religious leaders can be effective agents in promoting critical change in these areas.

Avian Influenza Virus Surveillance in High Arctic Breeding Geese, Greenland.

PubMed

Gaidet, Nicolas; Leclercq, India; Batéjat, Christophe; Grassin, Quentin; Daufresne, Tanguy; Manuguerra, Jean-Claude

2018-06-01

The connectedness in Arctic regions between migratory waterbird populations originating from different continents and the potential for virus exchange at their shared Arctic breeding ground point to the need to explore the largely unstudied circumpolar circulation of avian influenza viruses (AIV). We here report the investigation of AIV in wild birds and lakes in a high Arctic area of Northeast Greenland. No AIV could be detected in the fecal, feather, and water samples collected from large flocks of pink-footed geese Anser brachyrhynchus and barnacle geese Branta leucopsis in and around refuge lakes, where they congregate at high density during their flightless molting period in summer.

Complementary Information Derived from CRISPR Cas9 Mediated Gene Deletion and Suppression. | Office of Cancer Genomics

Cancer.gov

CRISPR-Cas9 provides the means to perform genome editing and facilitates loss-of-function screens. However, we and others demonstrated that expression of the Cas9 endonuclease induces a gene-independent response that correlates with the number of target sequences in the genome. An alternative approach to suppressing gene expression is to block transcription using a catalytically inactive Cas9 (dCas9). Here we directly compare genome editing by CRISPR-Cas9 (cutting, CRISPRc) and gene suppression using KRAB-dCas9 (CRISPRi) in loss-of-function screens to identify cell essential genes.

Oral Health Status of Older Adults Attending Senior Centers and Congregate Meal Sites in New Hampshire.

PubMed

Anderson, Ludmila; Martin, Nancy R; Kelly, Stephanie M; Brown, Heather A

2016-04-01

This study assessed the oral health status of older adults in randomly selected New Hampshire senior centers and congregate meal sites for the purpose of future planning, implementation and evaluation of targeted public health programs. A cross-sectional surveillance project was developed. Registered dental hygienists visually assessed denture use, number of natural teeth, teeth mobility, untreated caries, root fragments, gingivitis, need for care and treatment urgency among randomly selected active older adults living within New Hampshire communities. Altogether, 610 adults 60 years old and older attending 25 senior centers and congregate meal sites participated. Sixteen percent were edentulous and 42% reported having a removable upper or lower denture. Among edentulous adults, 5% had no dentures at all. Among 513 dentate participants, 22% had untreated caries, 14% had root fragments, 9% had gingivitis and 7% presented with obviously mobile teeth. Overall, 19% required early or urgent dental care. Differences were detected by sex, age group, urban versus rural location of the site and by the participation in a federal nutritional program for older adults. Baseline information about oral health needs of older adults in New Hampshire was gathered. Overall needs as well as existing oral health disparities will be addressed through the collaboration of public and private partners. Copyright © 2016 The American Dental Hygienists’ Association.

Urban waterfowl population: Ecological evaluation of management and planning

NASA Astrophysics Data System (ADS)

Greer, David M.

1982-05-01

An urban population of ducks in Puyallup, Washington, USA was studied for 14 consecutive months beginning in November 1978. Observations were made weekly from four study sites where ducks would congregate at early morning hours. Factors contributing to the presence of waterfowl in Puyallyup included abundant food supplies and a creek corridor that connected fragmented habitats in the urban area to the larger rural populations of waterfowl. Mallards ( Anas platyrhynchos) were the most abundant of the 13 species observed and were the only ducks remaining during the nesting season. Habitat size and complexity were important factors influencing the species diversity of a particular site. Nesting success of mallards was poor due to limited distribution of nesting habitat, intraspecific aggression, and human disturbance. Both site-specific and more broad-based strategies are suggested for managing and planning for duck populations in urban areas.

The health benefits of a physical activity program for older adults living in congregate housing.

PubMed

Temple, Brenda; Janzen, Bonnie L; Chad, Karen; Bell, Georgia; Reeder, Bruce; Martin, Linda

2008-01-01

In Saskatoon in 2002, as one of the key strategies for the in motion health promotion strategy, the Forever...in motion program was developed with the general goal of increasing opportunities for physical activity among older adults living in congregate housing. The three components of the program were a low-intensity exercise program, informal socialization and educational sessions. The objective of the present study was to examine whether participation in this program positively influenced participants' physical, emotional, psychological and social well-being. A quasi-experimental, pretest/post-test design was employed to examine the impact of the program on various aspects of participant well-being. Thirty-six program participants and a comparison group of 22 non-participants from two congregate housing facilities took part in the study. The pretest was administered to the study and comparison groups before or shortly after the 12-week session commenced, and the post-test was administered after the 12-week session had concluded. Pretest and post-test assessment consisted of self-report measures of (1) vitality, (2) self-rated health, 3) mental health, (4) social functioning, (5) role limitations due to emotional problems, 6) physical activity-related knowledge, and (7) self-efficacy for exercise. A multivariate analysis of covariance (MANCOVA) was conducted using the seven post-test scores as dependent variables and the pretest scores as covariates. After adjusting for differences in baseline characteristics, the findings revealed statistically significant improvements in self-reported health and self-efficacy for exercise in the program participant group as compared with non-participants. The results of this study suggest that a relatively low-cost, low-intensity exercise program such as the Forever...in motion program may positively influence the well-being of older adults living in congregate housing. However, additional research with a larger number of participants and a more rigorous study design is needed to further elucidate the health benefits of the Forever...in motion program.

The Effects of Quality of Life and Ability to Perform Activities of Daily Living on Mild Cognitive Impairment in Older People Living in Publicly Managed Congregate Housing.

PubMed

Chang, Chun-Feng; Yang, Rea-Jeng; Chang, Shu-Fang; Chou, Yuan Hwa; Huang, Ean-Wen

2017-06-01

Mild cognitive impairment (MCI) is characterized by a decrease in cognitive abilities that does not affect the ability to perform activities of daily living (ADLs). Therefore, this condition is easily overlooked. The prevalence and factors of influence for MCI in older people living in publicly managed congregate housing are currently unknown. This study investigated the prevalence and distribution of MCI in older people living in publicly managed congregate housing and assessed the correlations among quality of life (QoL), ADL, and MCI. This study applied a correlational study design. The participants were older people who met the study criteria and who lived in public housing in Wanhua District, Taipei City, Taiwan. One-on-one interviews were conducted to measure the cognitive abilities of the participants, and 299 valid samples were collected. The prevalence of MCI in older people living in publicly managed congregate housing was 16.1%. The χ test was employed to evaluate the distribution of MCI prevalence and indicated that the group with higher MCI prevalence exhibited the following characteristics: older than 81 years; married; lived in public housing for more than 20 years; cohabiting; had a history of drinking; and exhibited severe memory regression, physical disabilities, psychological distress, and low QoL. The difference between the groups achieved statistical significance (p < .05). After performing logistical regression analysis to control demographic variables, we found that QoL and ADL were critical for predicting MCI. This study confirmed that QoL and ADL correlate significantly with MCI in older people. Maintaining an open and supportive community enables older people to maintain sufficient mental activity, which has been shown to reduce MCI. These findings may provide an important reference for policy makers, educators, researchers, and community practitioners in their development of service strategies for older people.

Aerosol transport from Chiang Mai, Thailand to Mt. Lulin, Taiwan - Implication of aerosol aging during long-range transport

NASA Astrophysics Data System (ADS)

Chuang, Ming-Tung; Lee, Chung-Te; Chou, Charles C.-K.; Engling, Guenter; Chang, Shih-Yu; Chang, Shuenn-Chin; Sheu, Guey-Rong; Lin, Neng-Huei; Sopajaree, Khajornsak; Chang, You-Jia; Hong, Guo-Jun

2016-07-01

The transport of biomass burning (BB) aerosol from Indochina may cause a potential effect on climate change in Southeast Asia, East Asia, and the Western Pacific. Up to now, the understanding of BB aerosol composition modification during long-range transport (LRT) is still very limited due to the lack of observational data. In this study, atmospheric aerosols were collected at the Suthep/Doi Ang Khang (DAK) mountain sites in Chiang Mai, Thailand and the Lulin Atmospheric Background Station (Mt. Lulin) in central Taiwan from March to April 2010 and from February to April 2013, respectively. During the study period, an upwind and downwind relationship between the Suthep/DAK and Lulin sites (2400 km apart) was validated by backward trajectories. Comprehensive aerosol properties were resolved for PM2.5 water-soluble inorganic ions, carbonaceous content, water-soluble/insoluble organic carbon (WSOC/WIOC), dicarboxylic acids and their salts (DCAS), and anhydrosugars. A Modification Factor (MF) is proposed by employing non-sea-salt potassium ion (nss-K+) or fractionalized elemental carbon evolved at 580 °C after pyrolized OC correction (EC1-OP) as a BB aerosol tracer to evaluate the mass fraction changes of aerosol components from source to receptor regions during LRT. The MF values of nss-SO42-, NH4+, NO3-, OC1 (fractionalized organic carbon evolved from room temperature to 140 °C), OP (pyrolized OC fraction), DCAS, and WSOC were above unity, which indicated that these aerosol components were enhanced during LRT as compared with those in the near-source region. In contrast, the MF values of anhydrosugars ranged from 0.1 to 0.3, indicating anhydrosugars have degraded during LRT.

An enhanced procedure for measuring organic acids and methyl esters in PM2.5

NASA Astrophysics Data System (ADS)

Liu, F.; Duan, F. K.; He, K. B.; Ma, Y. L.; Rahn, K. A.; Zhang, Q.

2015-11-01

A solid-phase extraction (SPE) pretreatment procedure allowing organic acids to be separated from methyl esters in fine aerosol has been developed. The procedure first separates the organic acids from fatty acid methyl esters (FAMEs) and other nonacid organic compounds by aminopropyl-based SPE cartridge and then quantifies them by gas chromatography/mass spectrometry. The procedure prevents the fatty acids and dimethyl phthalate from being overestimated, and so allows us to accurately quantify the C4-C11 dicarboxylic acids (DCAs) and the C8-C30 monocarboxylic acids (MCAs). Results for the extraction of DCAs, MCAs, and AMAs in eluate and FAMEs in effluate by SAX and NH2 SPE cartridges exhibited that the NH2 SPE cartridge gave higher extraction efficiency than the SAX cartridge. The recoveries of analytes ranged from 67.5 to 111.3 %, and the RSD ranged from 0.7 to 10.9 %. The resulting correlations between the aliphatic acids and FAMEs suggest that the FAMEs had sources similar to those of the carboxylic acids, or were formed by esterifying carboxylic acids, or that aliphatic acids were formed by hydrolyzing FAMEs. Through extraction and cleanup using this procedure, 17 aromatic acids in eluate were identified and quantified by gas chromatography/tandem mass spectrometry, including five polycyclic aromatic hydrocarbon (PAH): acids 2-naphthoic, biphenyl-4-carboxylic, 9-oxo-9H-fluorene-1-carboxylic, biphenyl-4,4´-dicarboxylic, and phenanthrene-1-carboxylic acid, plus 1,8-naphthalic anhydride. Correlations between the PAH acids and the dicarboxylic and aromatic acids suggested that the first three acids and 1,8-naphthalic anhydride were secondary atmospheric photochemistry products and the last two mainly primary.

Quantitative analysis of glycerol in dicarboxylic acid-rich cutins provides insights into Arabidopsis cutin structure.

PubMed

Yang, Weili; Pollard, Mike; Li-Beisson, Yonghua; Ohlrogge, John

2016-10-01

Cutin is an extracellular lipid polymer that contributes to protective cuticle barrier functions against biotic and abiotic stresses in land plants. Glycerol has been reported as a component of cutin, contributing up to 14% by weight of total released monomers. Previous studies using partial hydrolysis of cuticle-enriched preparations established the presence of oligomers with glycerol-aliphatic ester links. Furthermore, glycerol-3-phosphate 2-O-acyltransferases (sn-2-GPATs) are essential for cutin biosynthesis. However, precise roles of glycerol in cutin assembly and structure remain uncertain. Here, a stable isotope-dilution assay was developed for the quantitative analysis of glycerol by GC/MS of triacetin with simultaneous determination of aliphatic monomers. To provide clues about the role of glycerol in dicarboxylic acid (DCA)-rich cutins, this methodology was applied to compare wild-type (WT) Arabidopsis cutin with a series of mutants that are defective in cutin synthesis. The molar ratio of glycerol to total DCAs in WT cutins was 2:1. Even when allowing for a small additional contribution from hydroxy fatty acids, this is a substantially higher glycerol to aliphatic monomer ratio than previously reported for any cutin. Glycerol content was strongly reduced in both stem and leaf cutin from all Arabidopsis mutants analyzed (gpat4/gpat8, att1-2 and lacs2-3). In addition, the molar reduction of glycerol was proportional to the molar reduction of total DCAs. These results suggest "glycerol-DCA-glycerol" may be the dominant motif in DCA-rich cutins. The ramifications and caveats for this hypothesis are presented. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Geotheral heating facilities of United Church of Christ (Congregational Church)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-07-01

Based on the assumptions made in this study, a geothermal system for the Congregational Church is not economically feasible at this time. A retrofit of the church for geothermal would result in a capital cost of $37,600 including the geothermal well. When this figure is considered in conjunction with the $1892 first-year savings (present fuel cost minus geothermal system O and M cost) and inflation over a 20-year period, a simple payback of 12 years results. In addition, an internal rate of return figure of 8.7 percent was generated. This indicates that the project would have to be financed atmore » less than 9 percent to be economically feasible over a 20-year period.« less

Ecological characteristics of core-use areas used by Bering-Chukchi-Beaufort (BCB) bowhead whales, 2006-2012

NASA Astrophysics Data System (ADS)

Citta, John J.; Quakenbush, Lori T.; Okkonen, Stephen R.; Druckenmiller, Matthew L.; Maslowski, Wieslaw; Clement-Kinney, Jaclyn; George, John C.; Brower, Harry; Small, Robert J.; Ashjian, Carin J.; Harwood, Lois A.; Heide-Jørgensen, Mads Peter

2015-08-01

The Bering-Chukchi-Beaufort (BCB) population of bowhead whales (Balaena mysticetus) ranges across the seasonally ice-covered waters of the Bering, Chukchi, and Beaufort seas. We used locations from 54 bowhead whales, obtained by satellite telemetry between 2006 and 2012, to define areas of concentrated use, termed "core-use areas". We identified six primary core-use areas and describe the timing of use and physical characteristics (oceanography, sea ice, and winds) associated with these areas. In spring, most whales migrated from wintering grounds in the Bering Sea to the Cape Bathurst polynya, Canada (Area 1), and spent the most time in the vicinity of the halocline at depths <75 m, which are within the euphotic zone, where calanoid copepods ascend following winter diapause. Peak use of the polynya occurred between 7 May and 5 July; whales generally left in July, when copepods are expected to descend to deeper depths. Between 12 July and 25 September, most tagged whales were located in shallow shelf waters adjacent to the Tuktoyaktuk Peninsula, Canada (Area 2), where wind-driven upwelling promotes the concentration of calanoid copepods. Between 22 August and 2 November, whales also congregated near Point Barrow, Alaska (Area 3), where east winds promote upwelling that moves zooplankton onto the Beaufort shelf, and subsequent relaxation of these winds promoted zooplankton aggregations. Between 27 October and 8 January, whales congregated along the northern shore of Chukotka, Russia (Area 4), where zooplankton likely concentrated along a coastal front between the southeastward-flowing Siberian Coastal Current and northward-flowing Bering Sea waters. The two remaining core-use areas occurred in the Bering Sea: Anadyr Strait (Area 5), where peak use occurred between 29 November and 20 April, and the Gulf of Anadyr (Area 6), where peak use occurred between 4 December and 1 April; both areas exhibited highly fractured sea ice. Whales near the Gulf of Anadyr spent almost half of their time at depths between 75 and 100 m, usually near the seafloor, where a subsurface front between cold Anadyr Water and warmer Bering Shelf Water presumably aggregates zooplankton. The amount of time whales spent near the seafloor in the Gulf of Anadyr, where copepods (in diapause) and, possibly, euphausiids are expected to aggregate provides strong evidence that bowhead whales are feeding in winter. The timing of bowhead spring migration corresponds with when zooplankton are expected to begin their spring ascent in April. The core-use areas we identified are also generally known from other studies to have high densities of whales and we are confident these areas represent the majority of important feeding areas during the study (2006-2012). Other feeding areas, that we did not detect, likely existed during the study and we expect core-use area boundaries to shift in response to changing hydrographic conditions.

Spring-summer movements of bonytail in a Colorado River reservoir, Lake Mohave, Arizona and Nevada

USGS Publications Warehouse

Marsh, Paul C.; Mueller, Gordon

1999-01-01

Bonytail can move substantial distances in a short time (10s of km in a few days). Fish in both years apparently favored the same areas, where they may remain for weeks. Unmarked bonytail were observed or captured by setting nets in places favored by tagged fish, a significant result since future use of the technique may enhance our ability to monitor reintroductions, locate and document spawning, examine habitat use, and acquire desperately needed brood stock for this critically imperiled species. External tagging techniques developed for juvenile razorback sucker may provide a method of minimizing telemetry induced stress while allowing us to focus sampling on congregation sites.

Conference Scene: nanomedicine kindles the development of the 'elixir of life'.

PubMed

Jain, Sanyog; Das, Manasmita

2011-06-01

For the seventh time, nanomedicine experts from around the globe congregated in SAS Nagar, Punjab, for the Fourth Winter School on Nanotechnology in Advanced Drug Delivery, organized by the National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India. The program covered almost all the scintillating areas of nanomedicine, including novel nanosystems for oral, ocular and transdermal drug delivery, nanostructured surfaces for medical applications, 'smart' nanobullets for site-specific drug and gene delivery, designer nanoparticles for therapeutic delivery, tissue engineering and nanobiocomposites, cancer nanotherapy, and novel analytical and diagnostic tools. Special emphasis was given to the commercialization of nanomedical products, including issues related to intellectual property and risk management.

Evaluation of Handgrip Strength and Nutritional Risk of Congregate Nutrition Program Participants in Florida.

PubMed

Springstroh, Kelly A; Gal, Nancy J; Ford, Amanda L; Whiting, Susan J; Dahl, Wendy J

2016-01-01

The aim of this study was to determine if handgrip strength (HGS) is a predictor of nutritional risk in community-dwelling older adults. A cross-sectional study was carried out to determine the relationship between HGS and nutritional risk using SCREEN 1. The setting was Congregate Nutrition program meal sites (n = 10) in North Central Florida and included community-dwelling older adults participating in the Congregate Nutrition program. Older adults (n = 136; 77.1 ± 8.9 y; 45 M, 91 F) participated in the study. Nutritional risk was identified in 68% of participants, with 10% exhibiting clinically relevant weakness (men, HGS < 26 kg; women, HGS < 16 kg), suggesting a vulnerable population. HGS was weakly associated with nutritional risk as assessed by SCREEN 1 (AUC = 0.59), but alternate cutpoints, 33 kg for men (mean of both hands) and 22 kg for women (highest of either hand), provided the best comparison to nutritional risk. In community-dwelling older adults, HGS was weakly associated with nutritional risk assessed using traditional screening. However, as existing research supports the inclusion of HGS in malnutrition screening in acute care, further research into the usefulness of HGS and possibly other measures of functional status in nutrition risk screening of community-dwelling older adults may be warranted.

Eating behaviors, mental health, and food intake are associated with obesity in older congregate meal participants.

PubMed

Porter Starr, Kathryn; Fischer, Joan G; Johnson, Mary Ann

2014-01-01

The relationship between eating behaviors, food intake, and mental health and the occurrence of obesity in older adults has rarely been investigated. Therefore, the objective of this study was to establish the associative links of these factors with two measures of obesity: class I obesity as indicated by body mass index (OB-BMI; BMI ≥ 30 kg/m²) and class I obesity as indicated by waist circumference (OB-WC; WC ≥ 43 inches for men and ≥ 42 inches for women). Older adults participating in the Older American's Act congregate meal program (N = 113, mean age = 74 years, 74% female, 45% African American) were assessed. Eating behaviors (cognitive restraint, uncontrolled eating, and emotional eating), food group choices (sweets, salty snacks, and fruits), and mental health indices (depression, anxiety, and stress) were recorded by questionnaire and related to measured occurrence of OB-BMI and OB-WC. In a series of multivariate logistical regression models, we found cognitive restraint to be consistently and robustly associated with both measures of obesity. In the fully adjusted model, cognitive restraint, consumption of sweets, anxiety, and lack of depression were associated with OB-WC. In summary, we found an association of obesity with abnormal eating behaviors, certain food group intakes, and mental health symptoms in this population. These findings may guide the development of future weight management interventions in a congregate meal setting.

Estimating bighorn sheep (Ovis canadensis) abundance using noninvasive sampling at a mineral lick within a National Park Wilderness Area

USGS Publications Warehouse

Schoenecker, Kathryn A.; Watry, Mary Kay; Ellison, Laura E.; Schwarz, Michael A.; Luikart, Gordon

2015-01-01

Conservation of species requires accurate population estimates. We used genetic markers from feces to determine bighorn sheep abundance for a herd that was hypothesized to be declining and in need of population status monitoring. We sampled from a small but accessible portion of the population's range where animals naturally congregate at a natural mineral lick to test whether we could accurately estimate population size by sampling from an area where animals concentrate. We used mark-recapture analysis to derive population estimates, and compared estimates from this smaller spatial sampling to estimates from sampling of the entire bighorn sheep range. We found that estimates were somewhat comparable; in 2009, the mineral lick sample and entire range sample differed by 20 individuals, and in 2010 they differed by only one individual. However, we captured 13 individuals in the entire range sample that were not captured at the mineral lick, and thus violated a model assumption that all individuals had an equal opportunity of being captured. This eliminated the possibility of inferring a total population estimate from just animals visiting the mineral lick, but because estimates were relatively similar, monitoring at the mineral lick can provide a useful index for management and conservation. We compared our results to a radio-collar study conducted in 2003–2004 and confirmed that the population remained stable since 2004. Our population estimates were 78 (CI 62–114) in 2009 and 95 (CI 77–131) in 2010. Between 7 and 11 sampling dates were needed to achieve a CV of 20% for population estimates, assuming a capture probability between 0.09 and 0.13. We relied on citizen science volunteers to maximize data collection and reduce costs; 71% of all fecal samples were collected by volunteers, compared to 29% collected by paid staff. We conclude that our technique provides a useful monitoring tool for managers. The technique could be tested and applied in similar populations where animals congregate with high fidelity at a mineral lick or other area.

Complex dynamics of a nonlinear voter model with contrarian agents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tanabe, Shoma; Masuda, Naoki, E-mail: masuda@mist.i.u-tokyo.ac.jp

2013-12-15

We investigate mean-field dynamics of a nonlinear opinion formation model with congregator and contrarian agents. Each agent assumes one of the two possible states. Congregators imitate the state of other agents with a rate that increases with the number of other agents in the opposite state, as in the linear voter model and nonlinear majority voting models. Contrarians flip the state with a rate that increases with the number of other agents in the same state. The nonlinearity controls the strength of the majority voting and is used as a main bifurcation parameter. We show that the model undergoes amore » rich bifurcation scenario comprising the egalitarian equilibrium, two symmetric lopsided equilibria, limit cycle, and coexistence of different types of stable equilibria with intertwining attractive basins.« less

Multidimensional Assessment of Spirituality/Religion in Patients with HIV: Conceptual Framework and Empirical Refinement

PubMed Central

Kudel, Ian; Cotton, Sian; Leonard, Anthony C.; Tsevat, Joel; Ritchey, P. Neal

2011-01-01

A decade ago, an expert panel developed a framework for measuring spirituality/religion in health research (Brief Multidimensional Measure of Religiousness/Spirituality), but empirical testing of this framework has been limited. The purpose of this study was to determine whether responses to items across multiple measures assessing spirituality/religion by 450 patients with HIV replicate this model. We hypothesized a six-factor model underlying a collective of 56 items, but results of confirmatory factor analyses suggested eight dimensions: Meaning/Peace, Tangible Connection to the Divine, Positive Religious Coping, Love/Appreciation, Negative Religious Coping, Positive Congregational Support, Negative Congregational Support, and Cultural Practices. This study corroborates parts of the factor structure underlying the Brief Multidimensional Measure of Religiousness/Spirituality and some recent refinements of the original framework. PMID:21136166

Multidimensional assessment of spirituality/religion in patients with HIV: conceptual framework and empirical refinement.

PubMed

Szaflarski, Magdalena; Kudel, Ian; Cotton, Sian; Leonard, Anthony C; Tsevat, Joel; Ritchey, P Neal

2012-12-01

A decade ago, an expert panel developed a framework for measuring spirituality/religion in health research (Brief Multidimensional Measure of Religiousness/Spirituality), but empirical testing of this framework has been limited. The purpose of this study was to determine whether responses to items across multiple measures assessing spirituality/religion by 450 patients with HIV replicate this model. We hypothesized a six-factor model underlying a collective of 56 items, but results of confirmatory factor analyses suggested eight dimensions: Meaning/Peace, Tangible Connection to the Divine, Positive Religious Coping, Love/Appreciation, Negative Religious Coping, Positive Congregational Support, Negative Congregational Support, and Cultural Practices. This study corroborates parts of the factor structure underlying the Brief Multidimensional Measure of Religiousness/Spirituality and some recent refinements of the original framework.

7 CFR 251.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... congregate Nutrition sites and projects that provide home-delivered meals; and (v) Disaster relief programs... households within the State having incomes below the poverty level and 40 percent on the number of unemployed...

4. Historic American Buildings Survey, Arthur W. LeBoeuf, Photographer, 1937 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey, Arthur W. LeBoeuf, Photographer, 1937 DETAIL OF WINDOW BREAKING INTO PEDIMENT. - First Congregational Church, 301 Benefit Street, Providence, Providence County, RI

Perceptions and activities of religious leaders on the prevention of HIV/AIDS and care of people living with the HIV infection in Ibadan, Nigeria.

PubMed

Asekun-Olarinmoye, Ifeoluwapo O; Asekun-Olarinmoye, Esther O; Fatiregun, A; Fawole, Olufunmilayo I

2013-01-01

The epidemic of human immunodeficiency virus (HIV) continues in Nigeria despite efforts to control it. Meaningful efforts aimed at combating this disease must be multisectoral. However, despite the major influence religious leaders have in this society, their role has not been well studied. The aim of the study was to assess the perceptions and activities of religious leaders on prevention of HIV/acquired immunodeficiency syndrome (AIDS) and care of people living with the virus in Ibadan, Nigeria. In a cross-sectional study, 336 leaders from eight religious denominations in Ibadan were surveyed utilizing a self-administered, semi-structured questionnaire. Respondents were selected by cluster sampling technique. Data was analyzed using the Statistical Package for Social Sciences software version 15. The mean age of respondents was 37.9 (± 13.5) years. The majority (97.6%) were aware of the HIV/AIDS scourge, and most had good knowledge of routes of transmission and modes of prevention (85.7%). Attitudes to people living with HIV/AIDS were positive in 84.2% respondents, and many practiced preventive measures (94.9%). One hundred and ninety (56.5%) respondents had ever preached about HIV/AIDS transmission and treatment to their congregations, while 257 (76.5%) used their position as a medium of educating their congregation about the dangers of HIV/AIDS and how to prevent it. Further analysis showed that respondents who were Christians (P = 0.026), had ever been married (P = 0.004), and were males (P = 0.002) were more likely to have ever preached about health issues to their congregations (individual role). The study concluded that the religious leaders are well informed about HIV/AIDS and have adequate knowledge and positive attitudes towards people living with AIDS. However, they need encouragement and training to enable them to more effectively harness their position for HIV prevention and to control programs and activities among their congregation to thereby play a crucial role in the war against HIV/AIDS in Nigeria.

Differences in Medical and Life-style Risk Factors for Malnutrition in Limited-Resource Older Adults in a Rural U.S. State: A Descriptive Study.

PubMed

Getty, M D; Mueller, M; Amella, E J; Fraser, A M

2016-02-01

Medical and life-style factors are associated with malnutrition in older adults. This study assessed the presence of these risk factors in limited-resource, community-dwelling older adults to inform the development of a nutrition education interventions. Quantitative descriptive study. A total of 24 randomly selected congregate nutrition sites (where limited-resource older adults can receive one hot meal/day, five days/week) in the rural state of South Carolina, USA. Data were collected from 477 older adults (of the 407 who reported race, 219 were African American and 171 were White). Extension Educators who work for the Cooperative Extension Service (a formalized educational outreach system associated with some U.S. universities) read aloud a 27-item instrument designed to assess risk factors for malnutrition. Response frequencies were tabulated and chi-square tests were performed using SAS 9.3. More African Americans reported having a chronic illness or condition (81.2 vs. 68.3%; p=0.003), eating alone (66.2 vs. 53.6%; p=0.012), having a refrigerator that sometimes did not keep food cold (31.8 vs. 8.4%; p<0.0001), and sometimes not having enough money to buy food (38.9 vs. 18.5%; p<0.0001) compared to White older adults. Rural older adults who attend congregate nutrition sites, especially African Americans, could be at risk for malnutrition due to health status and food preparation-related factors. Evidence-based, tailored programs are needed to minimize malnutrition among limited-resource older adults living in rural areas in the U.S.

Ecology of Avian Influenza Virus in Wild Birds in Tropical Africa.

PubMed

Gaidet, Nicolas

2016-05-01

Several ecologic factors have been proposed to describe the mechanisms whereby host ecology and the environment influence the transmission of avian influenza viruses (AIVs) in wild birds, including bird's foraging behavior, migratory pattern, seasonal congregation, the rate of recruitment of juvenile birds, and abiotic factors. However, these ecologic factors are derived from studies that have been conducted in temperate or boreal regions of the Northern Hemisphere. These factors cannot be directly translated to tropical regions, where differences in host ecology and seasonality may produce different ecologic interactions between wild birds and AIV. An extensive dataset of AIV detection in wildfowl and shorebirds sampled across tropical Africa was used to analyze how the distinctive ecologic features of Afrotropical regions may influence the dynamics of AIV transmission in wild birds. The strong seasonality of rainfall and surface area of wetlands allows testing of how the seasonality of wildfowl ecology (reproduction phenology and congregation) is related to AIV seasonal dynamics. The diversity of the African wildfowl community provides the opportunity to investigate the respective influence of migratory behavior, foraging behavior, and phylogeny on species variation in infection rate. Large aggregation sites of shorebirds in Africa allow testing for the existence of AIV infection hot spots. We found that the processes whereby host ecology influence AIV transmission in wild birds in the Afrotropical context operate through ecologic factors (seasonal drying of wetlands and extended and nonsynchronized breeding periods) that are different than the one described in temperate regions, hence, resulting in different patterns of AIV infection dynamics.

The community popular opinion leader HIV prevention programme: conceptual basis and intervention procedures.

PubMed

2007-04-01

To describe the community popular opinion leader (C-POL) intervention employed in the NIMH Collaborative HIV/STD Prevention Trial, including its theoretical, conceptual, and empirical basis, intervention procedures and methods, core elements, and how its content was culturally tailored to address the needs of varied populations. The programme is designed to identify, recruit, train, and intensively engage C-POLs of a target population to convey HIV risk reduction messages to people in their communities, with the intention of reducing high-risk behavior at a population level. Based on the diffusion of innovation theory, the intervention identified, trained, and engaged C-POL within a high-risk community population to advocate, recommend, and endorse the importance of safer behavior to other members of the same population. Nine core elements of the intervention are discussed. Data collected during rapid ethnography were used to adapt the content of the intervention for food market owners and workers in China, male patrons of wine shops and at-risk women congregating nearby in India, young people in social gathering venues in Peruvian barrios, dormitory students in Russia, and people congregating in commercial areas of growth points in Zimbabwe. The C-POL intervention model taps into community strengths, altruism, and people's desire to do something to help fight against AIDS. With few exceptions, C-POLs participated enthusiastically in the training sessions and reported having conversations in the community. Rapid ethnography can be used to tailor an intervention to diverse settings while maintaining fidelity to the core elements of the intervention.

12. Historic American Buildings Survey, Laurence E. Tilley, Photographer May, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. Historic American Buildings Survey, Laurence E. Tilley, Photographer May, 1958 AUDITORIUM FROM GALLERY TWOARD PULPIT AND SOUTH SIDE. - First Congregational Church, 301 Benefit Street, Providence, Providence County, RI

Classic Galaxy with Glamour

NASA Image and Video Library

2005-04-11

Young hot blue stars dominate the outer spiral arms of nearby galaxy NGC 300, while the older stars congregate in the nuclear regions which appear yellow-green in this image from NASA Galaxy Evolution Explorer.

Detail view of date stone marking the founding of the ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view of date stone marking the founding of the Emmanuel Christian Community Church congregation - Reformed Episcopal Church of the Rock of Ages, 1210 West Lanvale Street, Baltimore, Independent City, MD

Hope Grows with a Unique Partnership.

ERIC Educational Resources Information Center

Ducharme, Barbara Allegro

2002-01-01

Describes the Don Bosco project that involves representatives from a Minnesota school district and Rotary Clubs who are working with the Salesian Congregation in Costa Rica to provide education opportunities for all children. (JOW)

Church-Based Social Relationships, Belonging, and Health Among Older Mexican Americans

PubMed Central

Krause, Neal; Bastida, Elena

2011-01-01

The purpose of this study is to explain how church-based emotional support influences the health of older Mexican Americans. This issue is evaluated with a theoretical model that contains the following core linkages: (1) older Mexican Americans who go to church more often will be more likely to receive emotional support from fellow church members; (2) older Mexican Americans who receive more support from their fellow church members will be more likely to feel they belong in their congregation; (3) older Mexican Americans who feel they belong in their congregation are likely to have a stronger sense of personal control; and (4) older Mexican Americans who have a stronger sense of personal control are likely to enjoy better health. Data from a recent nationwide survey of older Mexican Americans provide support for each of these relationships. PMID:21687808

Increased Fruit and Vegetable Intake among Older Adults Participating in Kentucky's Congregate Meal Site Program

PubMed Central

Brewer, Dawn; Dickens, Emily; Humphrey, Alyson; Stephenson, Tammy

2016-01-01

The purpose of this study was to determine if the amount and variety of fruits and vegetables consumed increased among community-dwelling older adults participating in Kentucky's congregate meal site program following a series of five nutrition education lessons. A convenience sample of older adults attending senior centers (n=35), two intervention (n=19) and two control (n=16) centers, participated in this quasi-experimental pilot study. Following the intervention there was a significant increase in actual fruit and vegetable intake in the intervention group (p<0.05) as assessed by plate waste measurements of the congregate lunch meal. In addition, from pre- to post-intervention, a trend towards increased self-reported intake in the variety of fruit and vegetables was observed among the intervention group. As well, a significant increase in the number of days intervention participants self-reported consuming at least 4.5 cups of fruits and vegetables in the last seven days (2.44±2.09 days to 4.28±1.99 days (p=0.004)) was observed; and knowledge pertaining to phytochemicals increased (p<0.05). The phytochemical index (PI) score of the lunch meal, taking into account that the older adults consumption of meal components, including phytochemical-rich foods, was 26.9. Overall, study results indicated that a short theory-based nutrition education program offered to community-dwelling older adults was linked to an increase in fruit and vegetable consumption and phytochemical knowledge. PMID:28642630

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice.

PubMed

Zhou, Haibo; Liu, Junlai; Zhou, Changyang; Gao, Ni; Rao, Zhiping; Li, He; Hu, Xinde; Li, Changlin; Yao, Xuan; Shen, Xiaowen; Sun, Yidi; Wei, Yu; Liu, Fei; Ying, Wenqin; Zhang, Junming; Tang, Cheng; Zhang, Xu; Xu, Huatai; Shi, Linyu; Cheng, Leping; Huang, Pengyu; Yang, Hui

2018-03-01

Despite rapid progresses in the genome-editing field, in vivo simultaneous overexpression of multiple genes remains challenging. We generated a transgenic mouse using an improved dCas9 system that enables simultaneous and precise in vivo transcriptional activation of multiple genes and long noncoding RNAs in the nervous system. As proof of concept, we were able to use targeted activation of endogenous neurogenic genes in these transgenic mice to directly and efficiently convert astrocytes into functional neurons in vivo. This system provides a flexible and rapid screening platform for studying complex gene networks and gain-of-function phenotypes in the mammalian brain.

Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation.

PubMed

Dominguez, Antonia A; Lim, Wendell A; Qi, Lei S

2016-01-01

The bacterial CRISPR-Cas9 system has emerged as a multifunctional platform for sequence-specific regulation of gene expression. This Review describes the development of technologies based on nuclease-deactivated Cas9, termed dCas9, for RNA-guided genomic transcription regulation, both by repression through CRISPR interference (CRISPRi) and by activation through CRISPR activation (CRISPRa). We highlight different uses in diverse organisms, including bacterial and eukaryotic cells, and summarize current applications of harnessing CRISPR-dCas9 for multiplexed, inducible gene regulation, genome-wide screens and cell fate engineering. We also provide a perspective on future developments of the technology and its applications in biomedical research and clinical studies.

Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation

PubMed Central

Dominguez, Antonia A.; Lim, Wendell A.; Qi, Lei S.

2016-01-01

The bacterial CRISPR–Cas9 system has emerged as a multifunctional platform for sequence-specific regulation of gene expression. This Review describes the development of technologies based on nuclease-deactivated Cas9, termed dCas9, for RNA-guided genomic transcription regulation, both by repression through CRISPR interference (CRISPRi) and by activation through CRISPR activation (CRISPRa). We highlight different uses in diverse organisms, including bacterial and eukaryotic cells, and summarize current applications of harnessing CRISPR–dCas9 for multiplexed, inducible gene regulation, genome-wide screens and cell fate engineering. We also provide a perspective on future developments of the technology and its applications in biomedical research and clinical studies. PMID:26670017

7 CFR 249.6 - Participant eligibility.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Participant Eligibility... congregate nutrition services are provided, as categorically eligible to receive SFMNP benefits. (2...

7 CFR 249.6 - Participant eligibility.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Participant Eligibility... congregate nutrition services are provided, as categorically eligible to receive SFMNP benefits. (2...

7 CFR 249.6 - Participant eligibility.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Participant Eligibility... congregate nutrition services are provided, as categorically eligible to receive SFMNP benefits. (2...

7 CFR 249.6 - Participant eligibility.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Participant Eligibility... congregate nutrition services are provided, as categorically eligible to receive SFMNP benefits. (2...

7 CFR 249.6 - Participant eligibility.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Participant Eligibility... congregate nutrition services are provided, as categorically eligible to receive SFMNP benefits. (2...

Butterfly Social Clubs

Treesearch

Gary N. Ross

1998-01-01

Many diverse species of butterflies engage in a characteristic behavior that is commonly termed "puddling" and defined as a type of social behavior in which assorted butterflies, usually males, congregate at a damp site, often a mud puddle or stream bank.

Can Religion Help Prevent Obesity?: Religious Messages and the Prevalence of Being Overweight or Obese among Korean Women in California

PubMed Central

Ayers, John W.; Irvin, Veronica L.; Park, Hae-Ryun; Hovell, Melbourne F.; Hofstetter, Richard C.; Song, Yoonju; Paik, Hee-Yong

2010-01-01

This research examines the influence of messages from religious leaders and congregants on whether Korean women are overweight or obese. Data were drawn from telephone interviews with a probability sample (N=591) of women of Korean descent living in California. Overweight or obese prevalence was measured using World Health Organization standards for Asians (BMI>23). Respondents reported the frequency of messages discouraging “excessive eating” or encouraging “exercise” from religious leaders and congregants during a typical month. When conditioned on leaders’ messages, the frequency of congregants’ messages was associated with a significantly lower probability of being overweight or obese, although messages from either in the absence of the other were unassociated with being overweight or obese. At least for Korean women, religion may help prevent obesity via religious-based social mechanisms. PMID:20886700

Looking Inside the Black Box of “Attendance at Services”: New Measures for Exploring an Old Dimension in Religion and Health Research

PubMed Central

Idler, Ellen L.; Boulifard, David A.; Labouvie, Erich; Chen, Yung Y.; Krause, Tyrone J.; Contrada, Richard J.

2008-01-01

Research in religion and health has spurred new interest in measuring religiousness. Measurement efforts have focused on subjective facets of religiousness such as spirituality and beliefs, and less attention has been paid to congregate aspects, beyond the single item measuring attendance at services. We evaluate some new measures for religious experiences occurring during congregational worship services. Respondents (N=576) were religiously-diverse community-dwelling adults interviewed prior to cardiac surgery. Exploratory factor analysis of the new items with a pool of standard items yielded a readily interpretable solution, involving seven correlated but distinct factors and one index variable, with high levels of internal consistency. We describe religious affiliation and demographic differences in these measures. Attendance at religious services provides multifaceted physical, emotional, social, and spiritual experiences that may promote physical health through multiple pathways. PMID:19214241

Does Negative Interaction in the Church Increase Psychological Distress? Longitudinal Findings from the Presbyterian Panel Survey*

PubMed Central

Ellison, Christopher G.; Zhang, Wei; Krause, Neal; Marcum, John P.

2009-01-01

This study examines the effects of negative interaction in church on psychological distress. After outlining a series of theoretical arguments linking negative interaction with health and well-being, relevant hypotheses are tested using longitudinal data from two surveys of the 1997–1999 Presbyterian Panel, a nationwide panel of members and elders (lay leaders) in congregations of the Presbyterian Church (USA). Findings confirm that negative interaction appears to foster or exacerbate distress over the study period. In addition, specific dimensions of social negativity have distinctive effects; the impact of criticisms on distress surface only in cross-sectional models, while the effects of excessive demands emerge only in the longitudinal models. No subgroup variations in these effects are detected. Implications of these findings are discussed with regard to (a) research on religion and health and (b) congregational life, and a number of promising directions for future research are elaborated. PMID:20694051

Mortality in a migrating Mennonite church congregation.

PubMed

Everson, P M; Stevenson, J C; Rogers, L

1995-02-01

Preston's two-census method of demographic estimation is applied to three pairs of reconstructed censuses from the records of a migrating Mennonite church congregation covering the period 1780-1890. The three pairs of censuses correspond to three periods (1780-1790, 1850-1860, and 1880-1890) and to stays in three settings (Prussia, Russia, and Kansas, respectively). The Mennonites' stay in Prussia was a period of hardship. In Russia they expanded their economic base and developed new farming methods, dramatically increasing their productivity. The Mennonites took these skills to Kansas, where they continued to be successful. The increase in life expectancy at age 5 corroborates this picture. The Prussian period exhibits the shortest life expectancy for both sexes. After the move to Russia, life expectancy increased for both sexes and continued to increase with the move to Kansas. The model also provides limited evidence for fertility depression following the move to Kansas.

Porous metal oxide particles and their methods of synthesis

DOEpatents

Chen, Fanglin; Liu, Qiang

2013-03-12

Methods are generally disclosed for synthesis of porous particles from a solution formed from a leaving agent, a surfactant, and a soluble metal salt in a solvent. The surfactant congregates to form a nanoparticle core such that the metal salt forms about the nanoparticle core to form a plurality of nanoparticles. The solution is heated such that the leaving agent forms gas bubbles in the solution, and the plurality of nanoparticles congregate about the gas bubbles to form a porous particle. The porous particles are also generally disclosed and can include a particle shell formed about a core to define an average diameter from about 0.5 .mu.m to about 50 .mu.m. The particle shell can be formed from a plurality of nanoparticles having an average diameter of from about 1 nm to about 50 nm and defined by a metal salt formed about a surfactant core.

Black megachurch websites: an assessment of health content for congregations and communities.

PubMed

Campbell, Anthony D; Wallace, Gail

2015-01-01

This study examines the health-related content of Black megachurch websites in the southeastern United States. Data collection resulted in the identification of qualitative themes and frequencies of references to general health, specific health conditions, and corresponding general and specific health ministries. The most salient qualitative themes included holistic definitions of health, attention to racial health disparities, belief in divine health and protection from illness, emphasis on individual health responsibility, and belief in a religion-health connection. Nearly all websites referred to general health, and 74% mentioned a general health ministry. The most frequent references to specific health conditions included addiction, cancer, and HIV/AIDS, roughly corresponding to the top mentioned specific health ministries. This study provides baseline data on Black megachurch efforts to convey health information to their virtual congregations and communities. Findings support recent initiatives to involve megachurches in the provision of health messages within cultural frames to reach African Americans.

Chemistry and origin of minor and trace elements in vitrinite concentrates from a rank series from the eastern United States, England, and Australia

USGS Publications Warehouse

Lyons, P.C.; Palmer, C.A.; Bostick, N.H.; Fletcher, J.D.; Dulong, F.T.; Brown, F.W.; Brown, Z.A.; Krasnow, M.R.; Romankiw, L.A.

1989-01-01

A rank series consisting of twelve vitrinite concentrates and companion whole-coal samples from mined coal beds in the eastern United States, England, and Australia were analyzed for C, H, N, O, ash, and 47 trace and minor elements by standard elemental, instrumental neutron activation analysis (INAA), and direct-current-arc spectrographic (DCAS) techniques. The reflectance of vitrinite, atomic H:C and O:C, and ash-free carbon data were used to determine ranks that range from high-volatile C bituminous coal to meta-anthracite. A van Krevelen (atomic H:C vs. O:C) diagram of the vitrinite concentrates shows a smooth curve having its lowest point at H:C = 0.18 and O:C = 0.01. This improves the van Krevelen diagram by the addition of our vitrinite concentrate from meta-anthracite from the Narragansett basin of New England. Boron content (400-450 ppm) in two Illinois basin vitrinite concentrates was about an order of magnitude higher than B contents in other concentrates analyzed. We attribute this to marine origin or hydrothermal activity. The alkaline-earth elements Ca, Mg and Ba (DCAS) have higher concentrations in our vitrinite concentrates from bituminous coals of the Appalachian basin, than they do in vitrinite concentrates from the marine-roofed bituminous coals of the Illinois basin; therefore, a nonmarine origin for these alkaline-earth elements is postulated for the Appalachian basin coals. An ion-exchange mechanism due to high concentrations of these elements as ions in diagenetic water, but probably not recent ground water, may be responsible for the relatively high values of these elements in Appalachian concentrates. Higher concentrations of Ni and Cr in one of the English vitrinite concentrates and of Zr in the Australian concentrate probably indicate organic association and detrital influence, respectively. ?? 1989.

Obesity is more strongly associated with inappropriate eating behaviors than with mental health in older adults receiving congregate meals.

PubMed

Porter, Kathryn N; Johnson, Mary Ann

2011-01-01

This study explored the relationships of inappropriate eating behaviors and mental health with obesity in congregate meal participants in Georgia (N = 120, mean age = 75 years, 75% female, 43% African American). Inappropriate eating behaviors were evaluated with the Three-Factor Eating Questionnaire (18 questions); mental health was assessed with the Depression Anxiety Stress Scale (21 questions); history of depression was assessed with the Behavioral Risk Factor Surveillance Survey; and height and weight were measured to calculate body mass index (BMI) and obesity (52% ≥ 30 kg/m(2)). In bivariate analyses, obesity was associated with cognitive restraint (rho = 0.49, p < 0.0001), uncontrolled eating (rho = 0.22; p < 0.01), emotional eating (rho = 0.32, p < 0.001), and stress (rho = 0.18, p < 0.05), but not with depression or anxiety. In multivariate regression analyses including all six eating behavior and mental health indices, only cognitive restraint and emotional eating were consistently associated with obesity (p < 0.05) when controlled for potential confounders (demographics, food insecurity, and chronic health conditions). Thus, mental health symptoms and inappropriate eating behaviors, particularly cognitive restraint and emotional eating, may be important targets for future research and intervention. Additional research is needed to better understand how cognitive restraint and emotional eating contribute to obesity in this population so that interdisciplinary research and health care teams can appropriately prevent and manage obesity in congregate meal participants.

Key attributes of health ministries in African American churches: an exploratory survey.

PubMed

Carter-Edwards, Lori; Jallah, Yhenneko B; Goldmon, Moses V; Roberson, J T; Hoyo, Cathrine

2006-01-01

Church leaders are considered instrumental in the successful implementation of church-based health programs. However it is unknown which program attributes they perceive as important and which program attributes exist in their congregations. To explore the perceived importance and existence of health ministry-related attributes in predominately African American churches. Cross-sectional survey, with a convenience sample of 98 registered church leaders attending a conference on health and spirituality in Raleigh, NC. Attendees were asked to complete a brief survey assessing perceived importance (very important vs. somewhat or not important) and existence (yes vs. no) of 20, health ministry-related attributes in their churches. Percent perceived as very important, percent existence, and their differences were assessed for each attribute. Seventy-two (73.5%) of the attendees completed the survey. Attributes perceived as very important were: displaying health information in churches (73.6%); hosting health fairs for church members (73.2%); pastoral, church-based Internet access (70.8%); willingness to receive foundation funding for activities (66.7%); and incorporating health messages in Sunday bulletins (65.3%). For each of these program attributes, there was a gap between the proportion rating them "very important" and existence of the attribute in their own congregations (range diff in %: -8.3 to -22.2). Lack of generalizability due to sample selection and homogeneity. Among leaders surveyed, despite perceived importance, attributes did not exist for all. Future studies should evaluate whether attributes considered important by church leadership parallel an increase in the development and maintenance of health program activities, and are associated with congregation health behaviors and health outcomes.

Bowhead whale acoustic activity in the southeast Beaufort Sea during late summer 2008-2010.

PubMed

Charif, Russell A; Rahaman, Ashakur; Muirhead, Charles A; Pitzrick, Michael S; Warde, Ann M; Hall, James; Pyć, Cynthia; Clark, Christopher W

2013-12-01

Autonomous passive acoustic recorders were deployed to record sounds of bowhead whales (Balaena mysticetus) in the southeast Beaufort Sea for periods of 30-55 days during the late summer, open-water seasons of 2008-2010. Recordings were made in three areas licensed for hydrocarbon exploration, spanning the continental slope and adjacent outer shelf, and in a shallow inner-shelf area where bowheads have been observed congregating to feed in recent decades. Bowhead sounds were counted in samples comprising 10% of each recorded hour. In mid-August and September in all 3 years, the rate of bowhead calling at outer shelf sites exceeded that at adjacent continental slope sites by one to two orders of magnitude. Higher rates of calling occurred on the slope in late July and early August than at later dates. Calling rates varied by an order of magnitude between years in the one area that was monitored in different years. The highest rates of calling occurred on the inner shelf, offshore of the northern Tuktoyaktuk Peninsula. These trends are consistent with patterns of habitat use previously reported from aerial surveys in this and nearby areas of the Beaufort Sea and with the results of satellite tagging studies.

Social inclusion and community participation of individuals with intellectual/developmental disabilities.

PubMed

Amado, Angela Novak; Stancliffe, Roger J; McCarron, Mary; McCallion, Philip

2013-10-01

As more individuals with intellectual/developmental disabilities are physically included in community life, in schools, neighborhoods, jobs, recreation, and congregations, the challenge of going beyond physical inclusion to true social inclusion becomes more apparent. This article summarizes the status of the research about community participation and social inclusion, summarizes some debates and points of contention, notes emerging research issues, and highlights needed areas of research. It is clear that most research on these topics has been conducted with individuals who are in paid formal services, and there are great needs for understanding the community participation of individuals who live on their own or with their families, as well as researching social inclusion by focusing on the attitudes and experiences of community members themselves, not just individuals with disabilities and paid providers.

Functionalised carboxylic acids in atmospheric particles: An annual cycle revealing seasonal trends and possible sources

NASA Astrophysics Data System (ADS)

Teich, Monique; van Pinxteren, Dominik; Herrmann, Hartmut

2013-04-01

Carboxylic acids represent a major fraction of the water soluble organic carbon (WSOC) in atmospheric particles. Among the particle phase carboxylic acids, straight-chain monocarboxylic acids (MCA) and dicarboxylic acids (DCA) with 2-10 carbon atoms have extensively been studied in the past. However, only a few studies exist dealing with functionalised carboxylic acids, i.e. having additional hydroxyl-, oxo- or nitro-groups. Regarding atmospheric chemistry, these functionalised carboxylic acids are of particular interest as they are supposed to be formed during atmospheric oxidation processes, e.g. through radical reactions. Therefore they can provide insights into the tropospheric multiphase chemistry. During this work 28 carboxylic acids (4 functionalised aliphatic MCAs, 5 aromatic MCAs, 3 nitroaromatic MCAs, 6 aliphatic DCAs, 6 functionalised aliphatic DCAs, 4 aromatic DCAs) were quantitatively determined in 256 filter samples taken at the rural research station Melpitz (Saxony, Germany) with a PM10 Digitel DHA-80 filter sampler. All samples were taken in 2010 covering a whole annual cycle. The resulting dataset was examined for a possible seasonal dependency of the acid concentrations. Furthermore the influence of the air mass origin on the acid concentrations was studied based on a simple two-sector classification (western or eastern sector) using a back trajectory analysis. Regarding the annual average, adipic acid was found to be the most abundant compound with a mean concentration of 7.8 ng m-3 followed by 4-oxopimelic acid with 6.1 ng m-3. The sum of all acid concentrations showed two maxima during the seasonal cycle; one in summer and one in winter, whereas the highest overall acid concentrations were found in summer. In general the target acids could be divided into two different groups, where one group has its maximum concentration in summer and the other group during winter. The first group contains all investigated aliphatic mono- and dicarboxylic acids. The high concentrations in summer could lead to the conclusion that these acids are mostly formed during photochemical processes in the atmosphere. However, the concentrations in autumn were often exceeded by the ones in winter. Therefore probably other sources beside photochemical processes have to be considered. The second group consists of aromatic compounds. Because of the high concentrations in winter it can be concluded that photochemical formation plays a minor role and primary emission sources e.g., wood combustion are likely. Further evidence in determining sources of the carboxylic acids could be obtained from the air mass origin. In general, air masses transported from East have a more anthropogenic influence than the air mass inflow from West. For all aromatic carboxylic acids higher concentrations were determined during eastern inflow, indicating anthropogenic sources. This presumption is supported by high correlations with the elemental carbon (EC). Regarding the aliphatic carboxylic there is one group with higher concentrations when the air mass is transported from West and one with higher concentrations when air mass is transported from East. In summary the findings of this study reveal a clear difference in the seasonal trends of the single target acids indicating a variety of different sources.

Mid-Shelf Hardground Fish Habitats off the Georgia Coast

NASA Astrophysics Data System (ADS)

Platt, M.; Sautter, L.

2016-02-01

Multibeam sonar data were collected off the Georgia coast aboard the R/V Savannah by the College of Charleston BEAMS Program in May 2015. Kongsberg EM2040C data were post-processed in CARIS HIPS and SIPS 9.0 to create bathymetric maps overlain with backscatter intensity. The mid-shelf focus sites lie at depths between 25 and 40 m, and include the northern edge of Gray's Reef National Marine Sanctuary. The study sites are known areas of abundant fish congregations, identified by the South Carolina Department of Natural Resources' Marine Resources Monitoring, Assessment, & Prediction (MARMAP) program. The regional mid-shelf seafloor morphology consists of sand ridges, rock outcrops, and incised meandering channels 1 to 3 m deep. Backscatter analysis was used to identify hardground structures that might provide habitat for a high diversity of vertebrates and invertebrates. Multiple hardground structures were found and characterized at these locations and will be targeted for further research and possible inclusion in the Georgia and South Carolina continental shelf Marine Protected Areas.

33. Historic American Buildings Survey, Roy Oglesby, Photographer July 9, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

33. Historic American Buildings Survey, Roy Oglesby, Photographer July 9, 1947 ELEVATION OF PULPIT MADE FROM PEWS OF CHAPEL, CONGREGATIONAL CHURCH, FAIRFAX, SOUTH DAKOTA. - Old Fort Randall Church, Right Bank, Missouri River, Pickstown, Charles Mix County, SD

24 CFR 700.130 - Service coordinator.

Code of Federal Regulations, 2011 CFR

2011-04-01

... AND PUBLIC AND INDIAN HOUSING PROGRAMS) CONGREGATE HOUSING SERVICES PROGRAM § 700.130 Service...; (10) Educate grant recipient's program participants on such issues as benefits application procedures (e.g. SSI, food stamps, Medicaid), service availability, and program participant options and...

Sexuality Education as a Ministry

ERIC Educational Resources Information Center

Davis, Melanie J.

2011-01-01

The author describes her development from being her religious congregation's sexuality educator to completing doctoral studies and finding her place in the professional sexuality education community. She equates sexuality education to a ministry that reaches out to those in need of knowledge.

7. Historic American Buildings Survey (Fed.) Stanley P. Mixon, Photographer ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey (Fed.) Stanley P. Mixon, Photographer July 29, 1940 (A) EXTERIOR GENERAL VIEW FROM SOUTH (REAR) SIDE - First Church of Christ (Congregational), Main Street, between School & Church Streets, Farmington, Hartford County, CT

Trusteeship: shared mission for religious and laity.

PubMed

Longo, W L

1981-03-01

Serving as a trustee requires commitment to a particular congregation's spirit or charism and to the health care apostolate. Vatican Council II urges that laypersons take the responsibility to share with religious as partners in furthering the Church's mission.

Genetic and epigenetic control of gene expression by CRISPR–Cas systems

PubMed Central

Lo, Albert; Qi, Lei

2017-01-01

The discovery and adaption of bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems has revolutionized the way researchers edit genomes. Engineering of catalytically inactivated Cas variants (nuclease-deficient or nuclease-deactivated [dCas]) combined with transcriptional repressors, activators, or epigenetic modifiers enable sequence-specific regulation of gene expression and chromatin state. These CRISPR–Cas-based technologies have contributed to the rapid development of disease models and functional genomics screening approaches, which can facilitate genetic target identification and drug discovery. In this short review, we will cover recent advances of CRISPR–dCas9 systems and their use for transcriptional repression and activation, epigenome editing, and engineered synthetic circuits for complex control of the mammalian genome. PMID:28649363

SPATIAL AGGREGATION IN A FOREST FLOOR INSECT DEPENDS ON SEASONAL CONGREGATION AND SCATTERING EFFECTS OF PREDATORS

EPA Science Inventory

Spatial aggregations arising from gregarious behavior are common in nature and have important implications for population dynamics, community stability, and conservation. However, the translation of aggregation behaviors into emergent properties of populations and communities de...

Manual for Refugee Sponsorship.

ERIC Educational Resources Information Center

Brewer, Kathleen; Taran, Patrick A.

This manual provides guidelines for religious congregations interested in setting up programs to sponsor refugees. The manual describes the psychological implications of the refugee experience and discusses initial steps in organizing for sponsorship. Detailed information is provided for sponsors regarding: finances and mobilization of resources;…

Barriers and challenges affecting the contemporary church's engagement in health promotion.

PubMed

Ayton, Darshini; Manderson, Lenore; Smith, Ben J

2017-03-01

Issue addressed Christian churches have historically undertaken welfare and community service activities to practise faith and increase their relevance to communities. However, the church in Australia has received little attention from health promotion practitioners and researchers. The objective of this qualitative study was to explore the barriers and challenges that affect church engagement in health promotion to assist practitioners' understanding of the potential for these civil society organisations to play a role in health promotion programs and partnerships. Methods The research was based on interviews with five directors of church-affiliated organisations and with the church leaders (ministers, pastors, priests) of 30 churches in urban and rural Victoria. Analysis was iterative using open, axial and thematic coding. Results The challenges to church involvement in health promotion, as articulated by church leaders, fell under the themes of the social context of churches and the attributes of congregations. Major issues raised were perceived relevance, mistrust, contested agendas, discordant values within congregations, and risk management. Conclusion Although churches may take a different stance to health promotion agencies on a range of social and health issues, many have experience addressing social disadvantage and are prepared to commit resources to meet the needs of people outside their congregations. However, several factors inhibit the engagement of churches in health promotion including perceived irrelevance and community mistrust, agendas of conversion and values that conflict with health promotion. So what? Churches have a history of addressing social determinants of health such as housing, employment and food security. Deeper understanding of the challenges and barriers church leaders experience in undertaking health promotion work will facilitate more realistic and effective engagement by practitioners with these organisations.

7 CFR 250.69 - Disaster food assistance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... information: (A) Description of disaster situation; (B) Number of people requiring meals; (C) Period of time... State and Federal government) may be eligible to receive donated foods for congregate meal service or... meal service—(1) Approval authority and duration. Distributing agencies may review and approve...

7 CFR 250.69 - Disaster food assistance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... information: (A) Description of disaster situation; (B) Number of people requiring meals; (C) Period of time... State and Federal government) may be eligible to receive donated foods for congregate meal service or... meal service—(1) Approval authority and duration. Distributing agencies may review and approve...

7 CFR 3560.152 - Tenant eligibility.

Code of Federal Regulations, 2010 CFR

2010-01-01

... agreement that does not restrict occupancy by income. (c) Requirements for elderly housing, elderly units in... this section, the following occupancy requirements apply to elderly housing, elderly units in mixed housing, and congregate housing or group homes: (1) For elderly housing, elderly units in mixed housing...

7 CFR 3560.152 - Tenant eligibility.

Code of Federal Regulations, 2011 CFR

2011-01-01

... agreement that does not restrict occupancy by income. (c) Requirements for elderly housing, elderly units in... this section, the following occupancy requirements apply to elderly housing, elderly units in mixed housing, and congregate housing or group homes: (1) For elderly housing, elderly units in mixed housing...

49 CFR 397.7 - Parking.

Code of Federal Regulations, 2010 CFR

2010-10-01

... traveled portion of a public street or highway; (2) On private property (including premises of fueling or... bridge, tunnel, dwelling, or place where people work, congregate, or assemble, except for brief periods... public street or highway except for brief periods when the necessities of operation require the vehicle...

75 FR 41232 - Deer Flat National Wildlife Refuge, Canyon, Owyhee, Payette, and Washington Counties, ID; Malheur...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-15

... ducks congregate on the lake. When the lake is drawn down in late summer for irrigation, large numbers... mudflats. Duck populations peak in mid- December, with 40,000-70,000 ducks using Lake Lowell annually. The...

"Re-Acculturation" through Community-Based Religious Education

ERIC Educational Resources Information Center

Knight, Jennie S.

2011-01-01

Reflective engagement in reciprocal community partnerships holds tremendous potential for guiding members of congregations through the process of "re-acculturation." One of the "best practices" named in research about community-engaged learning for undergraduates is "re-acculturation"--an ongoing process of critical reflection about one's own…

A theory-based newsletter nutrition education program reduces nutritional risk and improves dietary intake for congregate meal participants.

PubMed

Francis, Sarah L; MacNab, Lindsay; Shelley, Mack

2014-01-01

At-risk older adults need community-based nutrition programs that improve nutritional status and practices. This 6-month study assessed the impact of the traditional Chef Charles (CC) program (Control) compared to a theory-based CC program (Treatment) on nutritional risk (NR), dietary intakes, self-efficacy (SE), food security (FS), and program satisfaction for congregate meal participants. Participants were mostly educated, single, "food secure" White females. NR change for the treatment group was significantly higher (P = 0.042) than the control group. No differences were noted for SE or FS change and program satisfaction between groups. The overall distribution classification levels of FS changed significantly (P < .001) from pre to post. Over half (n = 46, 76.7%) reported making dietary changes and the majority (n = 52, 86.7%) rated CC as good to excellent. Results suggest the theory-based CC program (treatment) is more effective in reducing NR and dietary practices than the traditional CC program (control).

Using concept mapping to mobilize a Black faith community to address HIV

PubMed Central

Szaflarski, Magdalena; Vaughn, Lisa M; McLinden, Daniel; Wess, Yolanda; Ruffner, Andrew

2017-01-01

Research that partners with community stakeholders increases contextual relevance and community buy-in and maximizes the chance for intervention success. Within a framework of an academic-community partnership, this project assessed a Black faith-community’s needs and opportunities to address HIV. We used concept mapping to identify/prioritize specific HIV-related strategies that would be acceptable to congregations. Ninety stakeholders brainstormed strategies to address HIV; 21 sorted strategies into groups and rated their importance and feasibility. Multidimensional scaling and cluster analysis were applied to the sorting to produce maps that illustrated the stakeholders’ conceptual thinking about HIV interventions. Of 278 responses, 93 were used in the sorting task. The visual maps represented eight clusters: church acceptance of people living with HIV; education (most feasible); mobilization and communication; church/leaders’ empowerment; church involvement/collaboration; safety/HIV prevention; media outreach; and, stigma (most important). Concept mapping clarified multifaceted issues of HIV in the Black faith community. The results will guide HIV programming in congregations. PMID:28239439

Social Network and Nutritional Value of Congregate Meal Programs: Differences by Sexual Orientation.

PubMed

Porter, Kristen; Keary, Sara; VanWagenen, Aimee; Bradford, Judith

2016-09-01

This study explored the associations between sexual orientation and the perceived social network and nutritional value of congregate meal programs (CMPs) in Massachusetts (N = 289). Descriptives, t tests, and chi-square tests analyzed sexual orientation differences. Linear regression tested the effects of sexual orientation on the value of CMPs. Sexual minorities (SMs) were more likely to have non-kin-based social networks and reported higher levels of loneliness compared with heterosexuals. Heterosexuals, fewer of whom have non-kin-based networks, place a stronger value on access to a social network via CMPs. Nutritional value is important for people of all sexual orientations. SMs traveled seven times the distance to attend CMPs, highlighting the need for greater access to such sites. Results of this study support the specification of SMs as a population of "greatest social need" under the Older Americans Act and the expansion of services that are tailored for their social support needs. © The Author(s) 2014.

The impact on social relationships of moving from congregated settings to personalized accommodation.

PubMed

McConkey, Roy; Bunting, Brendan; Keogh, Fiona; Garcia Iriarte, Edurne

2017-01-01

A natural experiment contrasted the social relationships of people with intellectual disabilities ( n = 110) before and after they moved from congregated settings to either personalized accommodation or group homes. Contrasts could also be drawn with individuals who had enduring mental health problems ( n = 46) and who experienced similar moves. Face-to-face interviews were conducted in each person's residence on two occasions approximately 24 months apart. Multivariate statistical analyses were used to determine significant effects. Greater proportions of people living in personalized settings scored higher on the five chosen indicators of social relationships than did persons living in grouped accommodation. However, multivariate statistical analyses identified that only one in five persons increased their social relationships as a result of changes in their accommodation, particularly persons with an intellectual disability and high support needs. These findings reinforce the extent of social isolation experienced by people with disabilities and mental health problems that changes in their accommodation only partially counter.

Characteristics of organic compounds in PM2.5 at urban and remote areas in Korea

NASA Astrophysics Data System (ADS)

Choi, A.; Lee, J.; Shin, H. J.; Lee, M.; Jin seok, H.; Lim, J.

2016-12-01

Organic aerosols contain thousands of organic compounds and contribute to 20%-90% of the total fine aerosol mass (Kanakidou et al., 2005). These organic aerosols originate from anthropogenic and natural (biogenic and geologic) sources and alter physical and chemical properties in the atmosphere depending on the atmospheric and meteorological conditions. About one hundred individual organic compounds in PM2.5 at Seoul (urban area) and Baengnyeong Island (remote area) were identified and quantified using gas chromatography/mass spectrometry (GC/MS) in order to understand the characteristics of organic compounds in PM2.5 at these areas. Further, major factors to determine their concentrations in the atmosphere were investigated. Organic compounds analyzed in this study were classified into six groups, n-alkanes, polycyclic aromatic hydrocarbons (PAHs), hopanes, fatty acids (FA), dicarboxylic acids (DCAs), and sugars. Daily variation of organic compounds concentrations at Seoul were not high, while, the concentrations of organic compounds at Baengnyeong Island showed high daily variation. This is might due to frequent change of source strength and/or SOA formation in this region. Through correlations of organic compounds with other air pollutants and factor analysis at both sites, it found that major factors (or source) for the determination of organic compounds concentrations at Seoul and Baengnyeong Island were different. The major sources at Seoul were anthropogenic sources such as vehicular emission and coal combustions, while, SOA formation and biomass burning were more attributed more to the organic compounds concentrations at Baengnyeong Island.References Kanakidou, M., Seinfeld, J.H., Pandis, S.N., Barnes, I., Dentener, F.J., Facchini, M.C., Van Dingenen, R., Ervens, B., Nenes, A., Nielsen, C.J., Swietlicki, E., Putaud, J.P., Balkanski, Y., Fuzzi, S., Horth, J., Moortgat, G.K., Winterhalter, R., Myhre, C.E.L., Tsigaridis, K., Vignati, E., Stephanou, E.G., Wilson, J., 2005. Organic aerosol and global climate modelling: a review. Atmos. Chem. Phys. 5, 1053e1123.

76 FR 50186 - Submission for OMB Emergency Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-12

... (ICR) to the Office of Management and Budget (OMB) for review and clearance in accordance with the.... Agency Number: None. Affected Public: Nonprofit organizations and congregations. Total Respondents: 600. Frequency: One time. Average Time per Response: 40 hours. Estimated Total Burden Hours: 24,000 hours. Total...

Case Studies of Action Research in Various Adult Education Settings.

ERIC Educational Resources Information Center

Kuhne, Gary W.; Weirauch, Drucie; Fetterman, David J.; Mearns, Raiana M.; Kalinosky, Kathy; Cegles, Kathleen A.; Ritchey, Linda

1997-01-01

Six case studies illustrate action research in adult education: faculty development in a museum, participation in a church congregation, retention of literacy volunteers in a corrections center, learner participation in a homeless shelter, technology innovation in a university, and infection control in a hospital. (SK)

Upending the Grammar of the Conventional Religious School

ERIC Educational Resources Information Center

Aron, Isa

2014-01-01

This article provides an overview and analysis of a relatively new phenomenon: congregational schools that have altered the conventional grammar of schooling, either through their structural arrangements or through their curricular approaches. Five pre-bar/bat mitzvah models are discussed: family schools, schools as communities,…

Supply and Demand: Religious Schooling in Ninteenth-Century France.

ERIC Educational Resources Information Center

Curtis, Sarah A.

1999-01-01

Examines the reasons behind the expansion of congregational primary education before the educational push of the Third Republic in the diocese of Lyon (France). Argues that the popularity of Catholic-sponsored schooling in Lyon depended on the conjuncture of religious philanthropy and cost effectiveness. (CMK)

24 CFR 945.103 - General policies.

Code of Federal Regulations, 2013 CFR

2013-04-01

... will not be housed in a designated project, PHAs shall utilize housing resources that they own, control... utilize, to the extent practicable, any housing facilities that they own or control in which supportive... housing, group homes, and congregate housing. (3) Exemption of mixed population projects. A PHA with a...

24 CFR 945.103 - General policies.

Code of Federal Regulations, 2012 CFR

2012-04-01

... will not be housed in a designated project, PHAs shall utilize housing resources that they own, control... utilize, to the extent practicable, any housing facilities that they own or control in which supportive... housing, group homes, and congregate housing. (3) Exemption of mixed population projects. A PHA with a...

24 CFR 945.103 - General policies.

Code of Federal Regulations, 2014 CFR

2014-04-01

... will not be housed in a designated project, PHAs shall utilize housing resources that they own, control... utilize, to the extent practicable, any housing facilities that they own or control in which supportive... housing, group homes, and congregate housing. (3) Exemption of mixed population projects. A PHA with a...

24 CFR 945.103 - General policies.

Code of Federal Regulations, 2011 CFR

2011-04-01

... will not be housed in a designated project, PHAs shall utilize housing resources that they own, control... utilize, to the extent practicable, any housing facilities that they own or control in which supportive... housing, group homes, and congregate housing. (3) Exemption of mixed population projects. A PHA with a...

24 CFR 945.103 - General policies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... will not be housed in a designated project, PHAs shall utilize housing resources that they own, control... utilize, to the extent practicable, any housing facilities that they own or control in which supportive... housing, group homes, and congregate housing. (3) Exemption of mixed population projects. A PHA with a...

Five Resources on Teaching Methods

ERIC Educational Resources Information Center

Simmons, Linda Wright

2009-01-01

This article offers five resources on teaching approaches that enhance learner participation and can be adapted inmost congregational learning contexts. These models emerge from diverse religious and secular perspectives; some are tailored for adult learners and some are ideal for learning in multicultural contexts. In alphabetical order, they are…

43 CFR 426.9 - Religious or charitable organizations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... charitable organization means an organization or each congregation, chapter, parish, school, ward, or similar... the criteria specified in paragraph (b)(1) of this section. (d) Affiliated farm management between a... entity while cooperating with a more central organization of the same affiliation in farm operation and...

43 CFR 426.9 - Religious or charitable organizations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... charitable organization means an organization or each congregation, chapter, parish, school, ward, or similar... the criteria specified in paragraph (b)(1) of this section. (d) Affiliated farm management between a... entity while cooperating with a more central organization of the same affiliation in farm operation and...

43 CFR 426.9 - Religious or charitable organizations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... charitable organization means an organization or each congregation, chapter, parish, school, ward, or similar... the criteria specified in paragraph (b)(1) of this section. (d) Affiliated farm management between a... entity while cooperating with a more central organization of the same affiliation in farm operation and...

43 CFR 426.9 - Religious or charitable organizations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... charitable organization means an organization or each congregation, chapter, parish, school, ward, or similar... the criteria specified in paragraph (b)(1) of this section. (d) Affiliated farm management between a... entity while cooperating with a more central organization of the same affiliation in farm operation and...

43 CFR 426.9 - Religious or charitable organizations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... charitable organization means an organization or each congregation, chapter, parish, school, ward, or similar... the criteria specified in paragraph (b)(1) of this section. (d) Affiliated farm management between a... entity while cooperating with a more central organization of the same affiliation in farm operation and...

Faith-Based Partnerships Promoting Health

ERIC Educational Resources Information Center

Rowland, Michael L.; Chappel-Aiken, Lolita

2012-01-01

Churches or, as they are now more commonly referred to in some circles, faith-based organizations (FBOs), have a rich tradition of providing not only religious but educational and social service opportunities for their congregations and local community. Social service agencies, health care agencies, and educational institutions have long realized…

From Icons to iPods: Visual Electronic Media Use and Worship Satisfaction

ERIC Educational Resources Information Center

Gilbert, Ronald

2010-01-01

A steady transition has been taking place in church services with the employment of visual electronic media intended to enhance the worship experience for congregants. Electronically assisted worship utilizes presentational software and hardware to incorporate video, film clips, texts, graphics, lyrics, TV broadcasts, Internet, Twitter, and even…

Disaggregating the Relationship Between Schools and Crime: A Spatial Analysis

ERIC Educational Resources Information Center

Murray, Rebecca K.; Swatt, Marc L.

2013-01-01

Although an extensive literature exists on crime in schools, surprisingly few studies have examined crime within the vicinity of schools. Schools, like other urban facilities, can generate crime by providing youth opportunities to congregate with little supervision, particularly before and after school hours. Some noteworthy studies have…

Mis-Education: A Recurring Theme? Transforming Black Religious and Theological Education

ERIC Educational Resources Information Center

Wright, Almeda M.

2017-01-01

Educating ministers and religious educators with the skills to connect with a variety of congregations and communities is a difficult task. Looking specifically at theological and religious education with African Americans, there are historical criticisms of "mis-education." "Mis-education" defined by Carter G. Woodson…

Catholic Women's Colleges in America.

ERIC Educational Resources Information Center

Schier, Tracy, Ed.; Russett, Cynthia, Ed.

The chapters in this collection provide a comprehensive history of Catholic women's colleges in the United States and how they have met the challenges of broader educational change. The chapters are: (1) "Faith, Knowledge, and Gender" (Jill Ker Conway); (2) "Colleges of Religious Women's Congregations: The Spiritual Heritage" (Monika K. Hellwig);…

Communication Supports in Congregate Residential Care Settings in Ohio

ERIC Educational Resources Information Center

Mitchell, Pamela R.

2009-01-01

Background: Communication skills are important to the pursuit of increased self-determination in individuals with disabilities. The aim of this investigation was to gather information about communication supports in state-run residential care facilities in Ohio, and to compare findings with a previous investigation on this topic examining such…

Scripture, Sin and Salvation: Theological Conservatism Reconsidered

ERIC Educational Resources Information Center

Hempel, Lynn M.; Bartkowski, John P.

2008-01-01

Using insights from ethnographic studies of conservative Protestant congregations, the authors propose and test a refined conceptual model of theological conservatism that accounts for three key components of a theologically conservative worldview: (1. epistemology, a belief in the Bible as the inspired word of God, (2. ontology, assumptions about…

Promoting Education for Sustainability in a Vaishnava (Hindu) Community

ERIC Educational Resources Information Center

Chauhan, Sheila; Rama das, Sita; Rita, Natalia; Haigh, Martin

2009-01-01

Education for a sustainable future aspires to increase pro-environmental behavior. This evaluates a project designed to help a British Vaishnava congregation reduce their ecological footprint by linking "Karma to Climate Change." It employs a tented educational experience fielded at major Hindu Festivals. Participants are guided through…

Social Inclusion and Community Participation of Individuals with Intellectual/Developmental Disabilities

ERIC Educational Resources Information Center

Amado, Angela Novak; Stancliffe, Roger J.; McCarron, Mary; McCallion, Philip

2013-01-01

As more individuals with intellectual/developmental disabilities are physically included in community life, in schools, neighborhoods, jobs, recreation, and congregations, the challenge of going beyond physical inclusion to true social inclusion becomes more apparent. This article summarizes the status of the research about community participation…

Sisters at Work: Career and Community Changes.

ERIC Educational Resources Information Center

Briody, Elizabeth K.; Sullivan, Teresa A.

1988-01-01

The authors examine occupational differentiation of U.S. Catholic nuns before and since the Second Vatican Council. Data were collected from interviews with 30 sisters representing 11 congregations. The analysis relates the diversification of their careers to changes in ideology and life-style and to the changing demographic and financial status…

Making the Monday Connection: Teaching Business Ethics in the Congregation.

ERIC Educational Resources Information Center

Van Buren, Harry J., III

1998-01-01

Discusses three factors that have contributed to the decline of eccelsiastical influences on the ethical decisions of Christians in the workplace. Considers the components of a business-ethics curriculum. Outlines one model for both teaching theological/philosophical bases for moral action and providing support groups for business people…

Academic Freedom and Tenure: The Catholic University of America.

ERIC Educational Resources Information Center

Davis, Bertram H.; And Others

1989-01-01

The Congregation for the Doctrine of the Faith, with the explicit approval of the Pope, declared that the Reverend Charles E. Curran was neither suitable nor eligible to teach Catholic Theology at The Catholic University of America. A report by the American Association of University Professors is presented. (MLW)

A Community of Learners

ERIC Educational Resources Information Center

Hedley, Mikell Lynne; Struble, Janet L.

2004-01-01

This article describes how a collaborative program with a local university provides learning for everyone involved. On the coldest day in the winter of 2000, a group of dedicated, excited high school students congregated at a research arboretum to meet Kevin Czajkowski, a geography professor from The University of Toledo. The professor had invited…

Multivariate Analyses of Social and Religious Attitudes.

ERIC Educational Resources Information Center

Meyer, Roger A.

The relationship between religious attitudes or orientations and prejudice was studied in a sample of 337 adults: college males, lay persons and ministers from local congregations, and seminary students in Louisiana and Texas. The study is based on Gordon Allport's theory concerning intrinsic and extrinsic religiousity. Ten religious groups were…

A Profile of Bereavement Supports in African American Church Congregations.

ERIC Educational Resources Information Center

Moore, Penelope J.; Hazell, LaVone V.; Honeyghan, Edna M.

Bereavement educators, counselors, clergy, and other specialists have observed that African Americans tend to under-utilize end-of-life palliative care services and general bereavement resources. The literature suggests that involving clergy in outreach to the African American community may be a viable strategy for developing bereavement supports.…

Methods for Data-based Delineation of Spatial Regions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilson, John E.

In data analysis, it is often useful to delineate or segregate areas of interest from the general population of data in order to concentrate further analysis efforts on smaller areas. Three methods are presented here for automatically generating polygons around spatial data of interest. Each method addresses a distinct data type. These methods were developed for and implemented in the sample planning tool called Visual Sample Plan (VSP). Method A is used to delineate areas of elevated values in a rectangular grid of data (raster). The data used for this method are spatially related. Although VSP uses data from amore » kriging process for this method, it will work for any type of data that is spatially coherent and appears on a regular grid. Method B is used to surround areas of interest characterized by individual data points that are congregated within a certain distance of each other. Areas where data are “clumped” together spatially will be delineated. Method C is used to recreate the original boundary in a raster of data that separated data values from non-values. This is useful when a rectangular raster of data contains non-values (missing data) that indicate they were outside of some original boundary. If the original boundary is not delivered with the raster, this method will approximate the original boundary.« less

Spatial and temporal use of a spawning site in the middle green river by wild and hatchery-reared razorback suckers

USGS Publications Warehouse

Modde, T.; Bowen, Z.H.; Kitcheyan, D.C.

2005-01-01

The population of endangered razorback suckers Xyrauchen texanus in the middle Green River (upper Colorado River basin) has declined during the last 40 years. The apparent cause for this decline is a lack of successful recruitment. This study used radiotelemetry to evaluate the ability of hatchery-reared razorback suckers to locate spawning areas where wild fish congregate during the ascending hydrographic limb of the snowmelt runoff. Hatchery-reared razorback suckers appeared to show similar reproductive behavior to wild fish. Both wild and hatchery-reared fish were found near the middle Green River spawning area between 1 and 25 May 2000. Hatchery fish occupied the same areas on the spawning site as wild fish, and remained on the spawning site during both nocturnal and diurnal hours. Males were more abundant on the spawning area than females, but the few females captured tended to stage away from the primary spawning area. The results from this study suggest hatchery-reared fish are capable of responding to natural cues that prompt spawning aggregations and are successful in locating existing spawning aggregations of wild fish. Given attention to stocking criteria, including genetic diversity and the size and time of stocking, the challenges of recovering razorback suckers will center on those factors that led to the population declines, particularly the survival of early life stages in off-channel habitats. ?? American Fisheries Society 2005.

Nowcasting for a high-resolution weather radar network

NASA Astrophysics Data System (ADS)

Ruzanski, Evan

Short-term prediction (nowcasting) of high-impact weather events can lead to significant improvement in warnings and advisories and is of great practical importance. Nowcasting using weather radar reflectivity data has been shown to be particularly useful. The Collaborative Adaptive Sensing of the Atmosphere (CASA) radar network provides high-resolution reflectivity data amenable to producing valuable nowcasts. The high-resolution nature of CASA data requires the use of an efficient nowcasting approach, which necessitated the development of the Dynamic Adaptive Radar Tracking of Storms (DARTS) and sinc kernel-based advection nowcasting methodology. This methodology was implemented operationally in the CASA Distributed Collaborative Adaptive Sensing (DCAS) system in a robust and efficient manner necessitated by the high-resolution nature of CASA data and distributed nature of the environment in which the nowcasting system operates. Nowcasts up to 10 min to support emergency manager decision-making and 1--5 min to steer the CASA radar nodes to better observe the advecting storm patterns for forecasters and researchers are currently provided by this system. Results of nowcasting performance during the 2009 CASA IP experiment are presented. Additionally, currently state-of-the-art scale-based filtering methods were adapted and evaluated for use in the CASA DCAS to provide a scale-based analysis of nowcasting. DARTS was also incorporated in the Weather Support to Deicing Decision Making system to provide more accurate and efficient snow water equivalent nowcasts for aircraft deicing decision support relative to the radar-based nowcasting method currently used in the operational system. Results of an evaluation using data collected from 2007--2008 by the Weather Service Radar-1988 Doppler (WSR-88D) located near Denver, Colorado, and the National Center for Atmospheric Research Marshall Test Site near Boulder, Colorado, are presented. DARTS was also used to study the short-term predictability of precipitation patterns depicted by high-resolution reflectivity data observed at microalpha (0.2--2 km) to mesobeta (20--200 km) scales by the CASA radar network. Additionally, DARTS was used to investigate the performance of nowcasting rainfall fields derived from specific differential phase estimates, which have been shown to provide more accurate and robust rainfall estimates compared to those made from radar reflectivity data.

The bile acid deoxycholic acid has a non-linear dose response for DNA damage and possibly NF-kappaB activation in oesophageal cells, with a mechanism of action involving ROS.

PubMed

Jenkins, G J S; Cronin, J; Alhamdani, A; Rawat, N; D'Souza, F; Thomas, T; Eltahir, Z; Griffiths, A P; Baxter, J N

2008-09-01

Deoxycholic acid (DCA) is a secondary bile acid implicated in various cancers of the gastrointestinal (GI) tract. In oesophageal adenocarcinoma, DCA is believed to contribute to carcinogenesis during reflux where stomach contents enter the lower oesophagus. It is imperative that we understand the mechanisms whereby oesophageal carcinogens function in order that therapeutic options may be developed. We have previously shown that DCA can damage chromosomes and does so through its generation of reactive oxygen species (ROS). We show here, after detailed experiments, that DCA appears to have a non-linear dose response for DNA damage. DCA induces DNA damage (as measured by the micronucleus assay) at doses of 100 microM and higher in oesophageal OE33 cells, but fails to induce such DNA damage below this cut-off dose. We also show that in terms of NF-kappaB activation (as measured by up-regulation of two NF-kappaB target genes) by DCA, a similar dose response is observed. This dose-response data may be important clinically as DCA exposure to the oesophagus may be used as a way to identify the 10% of Barrett's oesophagus patients currently progressing to cancer from the 90% of patients who do not progress. Only quantitative studies measuring DCA concentrations in refluxates correlated with histological progression will answer this question. We further show here that ROS are behind DCAs ability to activate NF-kappaB as antioxidants (epigallocatechin gallate, resveratrol and vitamin C) abrogate DCAs ability to up-regulate NF-kappaB-controlled genes. In conclusion, low doses of DCA appear to be less biologically significant in vitro. If this were to be confirmed in vivo, it might suggest that reflux patients with low DCA concentrations may be at a lower risk of cancer progression compared to patients with high levels of DCA in their refluxate. Either way, antioxidant supplementation may possibly help prevent the deleterious effects of DCA in the whole GI tract.

Public health and church-based constructions of HIV prevention: black Baptist perspective

PubMed Central

Roman Isler, Malika; Eng, Eugenia; Maman, Susanne; Adimora, Adaora; Weiner, Bryan

2014-01-01

The black church is influential in shaping health behaviors within African-American communities, yet few use evidence-based strategies for HIV prevention (abstinence, monogamy, condoms, voluntary counseling and testing, and prevention with positives). Using principles of grounded theory and interpretive description, we explored the social construction of HIV prevention within black Baptist churches in North Carolina. Data collection included interviews with church leaders (n = 12) and focus groups with congregants (n = 7; 36 participants). Analytic tools included open coding and case-level comparisons. Social constructions of HIV/AIDS prevention were influenced by two worldviews: public health and church-based. Areas of compatibility and incompatibility exist between the two worldviews that inform acceptability and adaptability of current evidence-based strategies. These findings offer insight into ways to increase the compatibility of evidence-based HIV prevention strategies within the black Baptist church context. PMID:24643141

[The need for psychiatrists in Chile. A projection for the year 2,000].

PubMed

Retamal, P

1991-12-01

In less than 15 year's time, the number of psychiatrists available should have increased twofold. It is thus calculated that about 500 psychiatrists would be working by 1990. An uneven regional distribution, however still survives with 80% of professionals congregated in the Chilean capital city area--less than 25% professionals working with the Health Services National System (SNSS) which is supposed to cover 75% of nationwide care. Besides, no psychiatric care is available as far as peripheral offices are concerned. By resorting to several parameters (vg. psychiatric needs according to prevalent pathologies, care demands, and ratio), as well as national data, and various author's opinion, it is estimated that about 650 psychiatrists will be needed in the year 2000. Hence, about 220 new psychiatrists should be trained during the 10 years ahead, if population's vegetative growth as well as replacements due to retirement, death, etc. are taken into account.

KSC-2014-2068

NASA Image and Video Library

2014-04-13

CAPE CANAVERAL, Fla. - SpaceWear team members Keith Hargett, left, and Alejandro Velasco participate in the International Space Apps Challenge in the Center for Space Education at the Kennedy Space Center Visitor Complex in Florida. Kennedy Space Center hosted one of the over 90 locations around the world where participants congregated for the attempt to design innovative solutions for global challenges over a 48-hour period. This year's development marathon focused on five NASA mission areas: Asteroids, Earth Watch, Human Spaceflight, Robotics, and Technology in Space. Three of this year’s challenges were developed by KSC employees: Space Wearables: Fashion Designer to Astronauts, Growing Food for a Martian Table, and Asteroid Prospector. The winners selected in 2014 at Kennedy were Astronaut Resource Managing System, or ARMS, for Best Use of Data and SpaceWear for Best Use of Hardware. ARMS also took the People's Choice Award. For more information, visit https://2014.spaceappschallenge.org. Photo credit: NASA/Daniel Casper

Welsh settlement patterns in a nineteenth-century Australian gold town.

PubMed

Tyler, Robert

2009-01-01

The adjacent gold mining settlements of Ballarat and Sebastopol in the colony of Victoria are universally acknowledged as the major focal point for Welsh immigrants in Australia in the second half of the nineteenth century. Here, the Welsh had congregated in sufficient numbers to establish an identifiable and highly visible ethnolinguistic community. Factors such as the necessity of acquiring the English language, movement out of the mining industry, high rates of exogamy, the failure to unite within one religious denomination and the conscious desire to integrate into mainstream Australian society, all served to undermine the integrity of that community. This paper argues that the more fundamental issue of residential propinquity was of primary importance in this process; that it was the failure of the Welsh immigrant group to establish and maintain long term exclusively Welsh areas of settlement that ensured the eventual dilution and absorption of the Welsh as a distinct community.

Riding the circuit for IRP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mashaw, R.

In its original usage, the term {open_quotes}circuit rider{close_quotes} described a minister supported by several congregations, who rode from rural church to rural church spreading religion. Today, thanks to a grant from the Department of Energy, there`s a new kind of circuit rider at work in small communities and rural areas, spreading the gospel of integrated resource planning. The concept of the circuit rider was advanced in 1994 by a coalition of associations, private businesses and government agencies, including the American Public Power Association, the National Rural Electric Cooperative Association, the federal power marketing agencies and the National Renewable Energy Laboratory.more » The group proposed to DOE the creation of a program for the advancement of integrated resource planning (IRP) in public power, designed to extend the resources and capabilities of publicly and cooperatively owned utilities in IRP by offering a several types of assistance, including training, direct consultation and publications.« less

Coming of Age

ERIC Educational Resources Information Center

Roberson, Kathy

2008-01-01

In the Unitarian tradition, Coming of Age (COA) is the counterpart of confirmations or bar/bat mitzvahs, with much less structure. Unitarians are all about freedom of thought, of belief, of expression, and this young adult rite of passage is an opportunity for each young person to say to the congregation, "This is what I believe." The author…

Operational, Social, and Religious Influences upon the Army Chaplain Field Manual, 1926-1952.

DTIC Science & Technology

2008-06-13

Within a few recent movies such as “Saving Private Ryan”2 and “Band of Brothers,” chaplains are angelic figures who can withstand enemy bullets while...In the early twentieth century, fundamentalist Christian faith groups did not allow members in their congregation to visit the movie theaters

Parables and Politics: Clergy Attitudes toward Illegal Immigration in Alabama

ERIC Educational Resources Information Center

Wickersham, Mary Eleanor

2013-01-01

The passage of a stringent immigration law in Alabama in 2011 makes relevant the juxtaposition of clergy and congregant attitudes and behaviors toward illegal immigrants as related to Biblical teachings that require charity to aliens. In order to examine the relationship between religious attitudes and illegal immigration, approximately 426…

Nutrition Education among Low-Income Older Adults: A Randomized Intervention Trial in Congregate Nutrition Sites

ERIC Educational Resources Information Center

Mitchell, Roger E.; Ash, Sarah L.; McClelland, Jacquelyn W.

2006-01-01

Nutritional well-being among older adults is critical for maintaining health, increasing longevity, and decreasing the impact of chronic illness. However, few well-controlled studies have examined nutritional behavior change among low-income older adults. A prospective, controlled, randomized design examined a five session nutrition education…

The Economics and Sociology of Religious Giving: Instrumental Rationality or Communal Bonding?

ERIC Educational Resources Information Center

Peifer, Jared L.

2010-01-01

Religious individuals commonly make sizable monetary sacrifices by contributing to their congregations. This social action resides in the overlap of religious and economic realms of behavior, creating a certain tension. Following a Weberian approach to social inquiry, I treat religious giving as social action whereby individuals direct their…

Connecting People: The Steps to Making it Happen

ERIC Educational Resources Information Center

Wightman, Clare

2009-01-01

People with higher support needs have been the last to benefit from the transformation of services for people with learning disabilities in the last few years. Despite often requiring expensive packages of support, this group are frequently offered services which are outdated and delivered in congregate, buildings-based and segregated settings. We…

Case Study: Austin Interfaith. Strong Neighborhoods, Strong Schools. The Indicators Project on Education Organizing.

ERIC Educational Resources Information Center

Simon, Elaine; Gold, Eva; Brown, Chris

This report describes Austin, Texas' Austin Interfaith, which connects community institutions that can support families (e.g., schools, congregations, and civic organization) and builds the capacity of family members to participate fully in the economic system. Viewing schools as key neighborhood institutions, Austin Interfaith works directly with…

I Wonder…Scientific Exploration and Experimentation as a Practice of Christian Faith

ERIC Educational Resources Information Center

Shaver, Ruth E.

2016-01-01

"I Wonder...Gaining Wisdom and Growing Faith Through Scientific Exploration" is an intergenerational science curriculum designed to be used in congregations. The goal of this curriculum and the theoretical work underpinning it is to counter the perception that people of faith cannot also be people who possess a scientific understanding…

Supporting Congregational Inclusion for Children and Youth with Disabilities and Their Families

ERIC Educational Resources Information Center

Carter, Erik W.; Boehm, Thomas L.; Annandale, Naomi H.; Taylor, Courtney E.

2016-01-01

Although considerable attention has focused on the inclusion of young people with intellectual and developmental disabilities in school, work, and residential settings, less is known about their involvement in religious activities. This article focuses on supporting the presence and participation of people with disabilities and their families in…

Bringing Evidence-Based Sexual Health Programs to Adolescents in Black Churches: Applying Knowledge from Systematic Adaptation Frameworks

ERIC Educational Resources Information Center

Weeks, Fiona H.; Powell, Terrinieka W.; Illangasekare, Samantha; Rice, Eric; Wilson, James; Hickman, Debra; Blum, Robert W.

2016-01-01

Previous studies have documented Black churches' receptivity to implementing adolescent sexual health programs within their congregations. Some authors have argued for new sexual health programs to be designed specifically for churches, similar to the development of school- and community-based interventions. However, strategies and curricula used…

Religious Socialization and Benevolence: A Study among American Pentecostals

ERIC Educational Resources Information Center

Cartledge, Mark J.

2013-01-01

This study explores benevolent action among Pentecostals in the USA using a congregational questionnaire survey of worshippers among the Church of God (Cleveland, TN) (N = 1522). The influence of religiosity and the socialization of a perceived relationship of love with God (Godly Love) are explored, while controlling for background variables. The…

Home-Schooling in Oldtown: The Education of a Virtuous Citizenry

ERIC Educational Resources Information Center

Howard, William L.

2009-01-01

Harriet Beecher Stowe (1811-1896) was the beneficiary of a unique blend of educational influences. The daughter, sister, and wife of Congregational ministers, she inherited the faith of New England Puritanism and its subsequent redirection by Jonathan Edwards (1703-1758). Studying and then teaching at her sister Catharine's female seminary, she…

Congregational Participation of a National Sample of Adults with Intellectual and Developmental Disabilities

ERIC Educational Resources Information Center

Carter, Erik W.; Kleinert, Harold L.; LoBianco, Tony F.; Sheppard-­Jones, Kathleen; Butler, Laura N.; Tyree, Milton S.

2015-01-01

Supporting people with intellectual and developmental disabilities (IDD) to thrive requires careful consideration of multiple avenues of community involvement. Yet little attention has focused on the place of faith community participation in the lives of adults with IDD. We examined attendance at religious services using National Core Indicator…

Mixing It up with Purpose

ERIC Educational Resources Information Center

Holladay, Jennifer

2010-01-01

The basketball players sit in a corner of the cafeteria. The rockers hang out near the stage. The ditchers and smokers congregate near the school gates. The JV football players and cheerleaders? They're near the field. This is how students at California's Hawthorne High described the typical lunch period at their school. In doing so, they also…

Mobile Learning 4ALL

ERIC Educational Resources Information Center

Correia, Secundino; Medeiros, Paula; Mendes, Mafalda; Silva, Margarida

2013-01-01

We are in an innovation process for the development of a new generation of tools and resources for education and training throughout life, available in any platform, at anytime and place and in any language. The project TOPQX intends to congregate a set of theoretical and empirical resources that form a scientific base from which it will be…

No Safety Net for Disabled Children in Residential Institutions in Ireland

ERIC Educational Resources Information Center

Conroy, Pauline

2012-01-01

The voices of adults and children with disabilities who have experienced violence and abuse are slowly beginning to surface in the public domain. Segregated residential institutions run by religious congregations appear to be dangerous places for children with disabilities and perceived differences--according to the former residents, speaking and…

Alternating Currents: Sacramental and Prophetic Imagining and Church Education

ERIC Educational Resources Information Center

Scott, Kieran

2016-01-01

This article advocates that education ought to be movement toward a unity of conflicting but complementary forces in the life of the congregation/parish. This paradox is captured best in the two divergent forms of imagination, namely, the sacramental and prophetic, both of which are grounded and united in their commitment to seeing ultimate…

What Would They Do? Latino Church Leaders and Domestic Violence

ERIC Educational Resources Information Center

Behnke, Andrew O.; Ames, Natalie; Hancock, Tina U.

2012-01-01

Understanding what Latino church leaders believe about domestic violence, and what they do when they confront it, is a key step in developing programs to help them engage in domestic violence prevention and intervention activities in their congregations. This article presents the findings from an exploratory study of 28 Latino church leaders. The…

Social Connections for Older People with Intellectual Disability in Ireland: Results from Wave One of IDS-TILDA

ERIC Educational Resources Information Center

McCausland, Darren; McCallion, Philip; Cleary, Eimear; McCarron, Mary

2016-01-01

Background: The literature on influences of community versus congregated settings raises questions about how social inclusion can be optimised for people with intellectual disability. This study examines social contacts for older people with intellectual disability in Ireland, examining differences in social connection for adults with intellectual…

Universities: Catholic and American, Responsible and Free.

ERIC Educational Resources Information Center

Gallin, Alice, Ed.

1987-01-01

The role of the theologian in Catholic colleges and universities is among several topics addressed in 11 articles. Some authors describe how they carry out the Catholic mission in higher education, while others focus on the historical background for the attempt by the Congregation for Catholic Education to describe and mandate a universal and…

Authority Base, Denomination, Moral Philosophy and the Power Strategies Used by Clergymen.

ERIC Educational Resources Information Center

Falbo, Toni; And Others

Clergymen are regarded by their congregations as having the authority to influence church members and clergymen are expected to exert influence. Three types of clerical authority have been identified: charismatic, traditional, and legal-rational. The common assumption that people select power strategies that are consistent with their perceptions…

The Unacceptable "Flaneur": The Shopping Mall as a Teenage Hangout.

ERIC Educational Resources Information Center

Matthews, Hugh; Taylor, Mark; Percy-Smith, Barry; Limb, Melanie

2000-01-01

Examines attitudes toward the role of the shopping mall as a place for congregating. Notes that adult attitudes reflect a discomfort with teenagers being in a place where they have no clear role, while teenagers transgress and question the spatial hegemony of adulthood, creating a "thirdspace" reflecting their place between adulthood and…

Indicators of Commitment to the Church: A Longitudinal Study of Church-Affiliated Youth.

ERIC Educational Resources Information Center

Dudley, Roger L.

1993-01-01

Examined late adolescents who drop out of church and others who remain committed to it. Survey of Seventh-day Adventist youth found commitment related to cognitive, experiential, and activity dimensions of religion. Ethical considerations, perception of one's importance to local congregation, and peer influence also played part in stepwise…

KSC-2010-5322

NASA Image and Video Library

2010-08-23

CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, two manatees congregate in brackish water off State Road 3, near the center's north guard gate. Kennedy coexists with the Merritt Island National Wildlife Refuge, habitat to more than 310 species of birds, 25 mammals, 117 fish and 65 amphibians and reptiles. Photo credit: NASA/Frank Michaux

Observation Projects: People-Watching for Fun and Learning.

ERIC Educational Resources Information Center

Litterst, Judith K.

In keeping with the trend toward active, participative learning, observation projects for speech communication students can allow them to experiment with designing and carrying out a study of human communication. Students can be encouraged to look at the dynamics of a church congregation, a courtroom, a pre-game football huddle, or an office, and…

[Syphilis in Ferrara in the nineteenth century].

PubMed

Angelini, Lauretta; Guidi, Enrica; Contini, Carlo

2009-06-01

In this article the authors highlight the behaviour of government authorities in the nineteenth century in Italy and especially in Ferrara to implement those measures deemed necessary to stem the spread of syphilis in epidemic form through the control of prostitution. Albeit discontinuously and until 1865, corrupted and infected women in Ferrara were assisted and treated by charitable institutions (Congregation of Charity, the Congregation of the Ladies of St. Vincent and the Sisters of Charity at the complex St. Mary of Consolation) since the Ferrara public hospital (Arcispedale S. Anna) could not accept or treat infected prostitutes for economic reasons and lack of beds. Subsequently, the hospital only treated prostitutes free of charge if they bore a certificate of poverty. The other infected prostitutes were sent to the sifilicomio in Modena. The authors also study mortality from syphilis in Ferrara from 1813 to 1899 in order to detect any significant differences according to age, sex and professional status and attempt to identify the stage of the disease (primary, secondary and tertiary), according to the terminology used by the doctors of that time.

A CRISPR-Based Toolbox for Studying T Cell Signal Transduction

PubMed Central

Chi, Shen; Weiss, Arthur; Wang, Haopeng

2016-01-01

CRISPR/Cas9 system is a powerful technology to perform genome editing in a variety of cell types. To facilitate the application of Cas9 in mapping T cell signaling pathways, we generated a toolbox for large-scale genetic screens in human Jurkat T cells. The toolbox has three different Jurkat cell lines expressing distinct Cas9 variants, including wild-type Cas9, dCas9-KRAB, and sunCas9. We demonstrated that the toolbox allows us to rapidly disrupt endogenous gene expression at the DNA level and to efficiently repress or activate gene expression at the transcriptional level. The toolbox, in combination with multiple currently existing genome-wide sgRNA libraries, will be useful to systematically investigate T cell signal transduction using both loss-of-function and gain-of-function genetic screens. PMID:27057542

Health care and personal care needs among residents in nursing homes, group homes, and congregate housing in Japan: why does transition occur, and where can the frail elderly establish a permanent residence?

PubMed

Nakanishi, Miharu; Hattori, Keiko; Nakashima, Taeko; Sawamura, Kanae

2014-01-01

Japan has had high rates of transition to nursing homes from other long term care facilities. It has been hypothesized that care transitions occur because a resident's condition deteriorates. The aim of the present study was to compare the health care and personal care needs of residents in nursing homes, group homes, and congregate housing in Japan. The present study was conducted using a cross-sectional study design. The present study included 70,519 elderly individuals from 5 types of residential facilities: care medical facilities (heavy medical care; n = 17,358), geriatric intermediate care facilities (rehabilitation aimed toward a discharge to home; n = 26,136), special nursing homes (permanent residence; n = 20,564), group homes (group living, n = 1454), and fee-based homes for the elderly (congregate housing; n = 5007). The managing director at each facility provided information on the residents' health care and personal care needs, including activities of daily living (ADLs), level of required care, level of cognitive impairment, current disease treatment, and medical procedures. A multinomial logistic regression analysis demonstrated a significantly lower rate of medical procedures among the residents in special nursing homes compared with those in care medical facilities, geriatric intermediate care facilities, group homes, and fee-based homes for the elderly. The residents of special nursing homes also indicated a significantly lower level of required care than those in care medical facilities. The results of our study suggest that care transitions occur because of unavailable permanent residence option for people who suffer with medical deterioration. The national government should modify residential facilities by reorganizing several types of residential facilities into nursing homes that provide a place of permanent residence. Copyright © 2014 American Medical Directors Association, Inc. Published by Elsevier Inc. All rights reserved.

The scientific production in trauma of an emerging country

PubMed Central

2012-01-01

Background The study aims to examine whether the end of specialty in trauma surgery in 2003 influenced the scientific productivity of the area in Brazil. Methods We identified and classified the manuscripts and their authors, from databases such as PubMed, Scielo and Plataforma Lattes and sites like Google, in addition to the list of members of SBAIT, the sole society in Brazil to congregate surgeons involved in trauma care in the country. We applied statistical tests to compare the periods of 1997-2003 and 2004-2010. We also analyzed the following variables: impact factor of journals in which manuscripts were published, journals, regional origin of authors, time since graduation, and conducting post-doctorate abroad. Results We observed a significant increase in publication rates of the analyzed groups over the years. There was a predominance of quantitative studies from the Southeast (especially the state of São Paulo). More time elapsed after graduation and the realization of postdoctoral studies abroad influenced the individual scientific productivity. Conclusion The number of articles published by authors from the area of trauma has been growing over the past 14 years in Brazil. The end of the specialty in trauma surgery in the country did not influence the scientific productivity in the area. PMID:23531364

At-sea distribution of satellite-tracked grey-faced petrels, Pterodroma macroptera gouldi, captured on the Ruamaahua (Aldermen) Islands, New Zealand

USGS Publications Warehouse

MacLeod, Catriona; Adams, Josh; Lyver, Phil

2008-01-01

We used satellite telemetry to determine the at-sea distribution of 32 adult (non-breeders and failed breeders) Grey-faced Petrels, Pterodroma macroptera gouldi, during July-October in 2006 and 2007. Adults captured at breeding colonies on the Ruamaahua (Aldermen) Islands ranged across the southwestern Pacific Ocean and Tasman Sea between 20-49°S and 142°E and 1300 W Petrels were located almost exclusively over offshore waters> 1000 m depth. The extent oftheir distributions was similar across years, but petrels ranged farther south and west in 2006. Individuals displayed a high degree ofspatial overlap (48-620/0 among individuals) and area use revealed three general "hotspots" within their overall range: waters near the Ruamaahua Islands; the central Tasman Sea; and the area surrounding the Chatham Rise. In July-August 2006, most petrels congregated over the Tasman Sea, but for the same period in 2007 were predominantly associated with Chatham Rise. The home ranges of petrels tended to overlap disproportionately more than expected with the Australian Exclusive Economic Zone and less than expected with High Seas, relative to the area available in each zone, in July-August 2006. Accordingly, multiple nations are responsible for determining potential impacts resulting from fisheries bycatch and potential resource competition with Grey-faced Petrels.

The Relationship between the Catholic Teacher's Faith and Commitment in the Catholic High School

ERIC Educational Resources Information Center

Cho, Young Kwan

2011-01-01

Church documents recognize that the Catholic teacher's faith, mediated through a teacher's commitment, is one of the crucial factors that guarantees the success of the Catholic school (Congregation for Catholic Education, 1977, 1982, 2007). A number of researchers support this view with their findings (Ciriello, 1987; Tarr, 1992; Tiernan, 2000).…

1987 Mosquito Identifications from USAF Installations in the Pacific Region

DTIC Science & Technology

1989-03-20

concentration); apply to shrubs, lower trees, and lawns chlorpyrifos (DursbanR) 44.4% EC, 0.8 - 1.6 fl oz/Ac propoxur (BaygonR) 13.9% EC, 8 fl oz/gal (1.1...finished concentration), apply to screens, doors, window frames, and other mosquito congregation surfaces. carbaryl (SevinR) 0.33 - 1.25 lb of 80

Pretending to Be Japanese: Artistic Play in a Japanese-American Church and Family

ERIC Educational Resources Information Center

Goto, Courtney T.

2008-01-01

With high rates of out-marriage and dwindling need for bilingual worship, Japanese-American churches face a critical question: "Why retain the Japanese part of our identity?" This article explores how one layperson (Naomi Takahashi Goto) draws from her experience as an artist, teacher, and mother to help her congregation answer this question.…

Congregating to Create for Social Change: Urban Youth Media Production and Sense of Community

ERIC Educational Resources Information Center

Charmaraman, Linda

2013-01-01

This case study explored how adolescents were empowered through afterschool media production activities and, in the process, re-imagined themselves as active and engaged citizens within their community. Through analyzing interviews, participant observations, and media artifacts of 14 participants (aged 15-19) over a period of 18 months, three main…

Spiritual Supports and Inclusive Congregational Ministries: Celebrating Gifts beyond the Holidays

ERIC Educational Resources Information Center

Gaventa, Bill

2011-01-01

This article describes what is happening in the world of spiritual supports for children and adults with disabilities and their families. The good news is that individuals with disabilities are being seen all year long in many faith communities, families with kids with special needs are being welcomed and supported, and, best of all, there is…

Religious Socialization: A Test of the Channeling Hypothesis of Parental Influence on Adolescent Faith Maturity.

ERIC Educational Resources Information Center

Martin, Todd F.; White, James M.; Perlman, Daniel

2003-01-01

This study used a sample of 2,379 seventh through twelfth graders in 5 Protestant denominations to test the hypothesis that parental influences on religious faith are mediated through peer selection and congregation selection. Findings revealed that peer and parental influence remained stable during the adolescent years. Parental influence did not…

Peer Effects in Drug Use and Sex among College Students.

ERIC Educational Resources Information Center

Duncan, Greg J.; Boisjoly, Johanne; Kremer, Michael; Levy, Dan M.; Eccles, Jacque

2005-01-01

Past research suggests that congregating delinquent youth increases their likelihood of problem behavior. We test for analogous peer effects in the drug use and sexual behavior of male (n = 279) and female (n = 435) college students, using data on the characteristics of first-year roommates to whom they were randomly assigned. We find that males…

Abies religiosa habitat prediction in climatic change scenarios and implications for monarch butterfly conservation in Mexico

Treesearch

Cuauhtemoc Saenz-Romero; Gerald E. Rehfeldt; Pierre Duval; Roberto A. Lindig-Cisneros

2012-01-01

Abies religiosa (HBK) Schl. & Cham. (oyamel fir) is distributed in conifer-dominated mountain forests at high altitudes along the Trans-Mexican Volcanic Belt. This fir is the preferred host for overwintering monarch butterfly (Danaus plexippus) migratory populations which habitually congregate within a few stands now located inside a Monarch Butterfly Biosphere...

Historical Analysis of the Division between Clergy and Laity with Particular Reference to Discipleship

ERIC Educational Resources Information Center

Copeland, Janet Eileen

2012-01-01

This dissertation analyzes the change from the New Testament church practice of having the responsibility for ministry rest upon the entire congregation, clergy and laity alike, to the current practice of the responsibility for ministry resting almost exclusively upon the clergy. Chapter 1 introduces the concept of Christians being accountable to…

Authentic Expression of Edmund Rice Christian Brother Education

ERIC Educational Resources Information Center

Vercruysse, Raymond J.

2007-01-01

In 1802, Edmund Rice directed the laying of the foundation stone for Mount Sion Monastery and School. After several previous attempts of instructing poor boys in Waterford, this was to be the first permanent home for the Congregation of Christian Brothers. Rice's dream of founding a religious community of brothers was becoming a reality with a…

Missionaries and Tonic Sol-fa Music Pedagogy in 19th-Century China

ERIC Educational Resources Information Center

Southcott, Jane E.; Lee, Angela Hao-Chun

2008-01-01

In the 19th century, Christian missionaries in China, as elsewhere, used the Tonic Sol-fa method of music instruction to aid their evangelizing. This system was designed to improve congregational singing in churches, Sunday schools and missions. The London Missionary Society and other evangelical groups employed the method. These missionaries took…

Preferences for Prolonging Life: A Prospect Theory Approach

ERIC Educational Resources Information Center

Winter, Laraine; Lawton, M. Powell; Ruckdeschel, Katy

2003-01-01

Kahneman and Tversky's (1979) Prospect theory was tested as a model of preferences for prolonging life under various hypothetical health statuses. A sample of 384 elderly people living in congregate housing (263 healthy, 131 frail) indicated how long (if at all) they would want to live under each of nine hypothetical health conditions (e.g.,…

Diagnostic Grouping among Adults with Intellectual Disabilities and Autistic Spectrum Disorders in Staffed Housing

ERIC Educational Resources Information Center

Felce, D.; Perry, J.

2012-01-01

Background: There is little evidence to guide the commissioning of residential provision for adults with autistic spectrum disorder (ASD) in the UK. We aim to explore the degree and impact of diagnostic congregation among adults with intellectual disabilities (ID) and ASD living in staffed housing. Methods: One hundred and fifty-seven adults with…

Sociology of Twentieth Century Congregate Care of the Developmentally Disabled-Recollections

ERIC Educational Resources Information Center

Daly, William C.

2005-01-01

Elements of the twentieth century care facility of state origin are enumerated as the reader hopefully gets some idea of the social milieu or ethos of that period and the management profile thought to be proper and expeditious for unfortunate, homeless and poorly adjusted citizens. The life of staff and patients within these state sponsored…

An Evaluation of the Nutrition Services for the Elderly. Volume I. Executive Summary.

ERIC Educational Resources Information Center

Kirschner Associates, Inc., Albuquerque, NM.

This document is part of a five-volume nationwide study of Nutrition Services operations and elderly citizens participating in congregate dining and home delivery services authorized by Title III-C of the Older Americans' Act. The Nutrition Services address a number of problems faced by the nation's elderly, such as dietary inadequacy, declining…

The Catholic Church & Social Justice Issues: An Expose of Vatican Power in America.

ERIC Educational Resources Information Center

Mumford, Stephen D.

1983-01-01

Three popular modern movements--ERA, family planning, and legal abortion--all undermine church authority and power by having as their ends the promotion of acts that completely counter the tenets with which the church leadership has indoctrinated its congregants. Actions the Vatican has taken to counter these threats are discussed. (RM)

The Influence of Depression, and Family and Friendship Relations, on Residents' Loneliness in Congregate Housing.

ERIC Educational Resources Information Center

Mullins, Larry C.; Dugan, Elizabeth

1990-01-01

Examined impact of various social relationships on level of loneliness reported by 208 elderly residents of 10 senior housing apartments, controlling for depression. Subjects who were less satisfied with quality of their relationships and had less contact with close friends were more lonely. Whether one had children, grandchildren, siblings, or…

Predictors of HIV/AIDS Programming in African American Churches: Implications for HIV Prevention, Testing, and Care

ERIC Educational Resources Information Center

Stewart, Jennifer M.; Hanlon, Alexandra; Brawner, Bridgette M.

2017-01-01

Using data from the National Congregational Study, we examined predictors of having an HIV/AIDS program in predominately African American churches across the United States. We conducted regression analyses of Wave II data (N = 1,506) isolating the sample to churches with a predominately African American membership. The dependent variable asked…

Campus-Public Partnerships: Successful Models for Strategic and Facilities Planning

ERIC Educational Resources Information Center

McHugh, Kenneth A.; Meister, Richard J.

2004-01-01

Founded in 1898 by the Congregation of the Mission (Vincentians), in the past 18 years DePaul University has transformed itself from a commuter institution, "the little school under the El," to the largest Catholic university in the United States and the seventh largest private university. It has increased its enrollment by 11,000…

United States Living Arrangements of People with Intellectual and/or Developmental Disabilities in 1995

ERIC Educational Resources Information Center

Larson, Sheryl A.; Doljanac, Robert; Lakin, K. Charlie

2005-01-01

In the United States, data on the number of people with intellectual or developmental disabilities (ID/DD) living in institutional and other congregate care settings have been gathered and reported since 1977 through the Residential Information Systems Program (RISP) at the University of Minnesota (e.g., Prouty & Lakin, 1997). These data were…

Judeo-Spanish Language Maintenance Efforts in the United States.

ERIC Educational Resources Information Center

Malinowski, Arlene

The aim of the paper is to ascertain the size and cultural vitality of the Sephardic component of the 50 Sephardic congregations and communities in the United States. Particular attention is focused on the extent to which Judeo-Spanish, the language of the Sephardim, continues to play a role within the group. The history of Sephardic expulsion and…

A Movie Case Study of Anemic Jewish Education

ERIC Educational Resources Information Center

Resnick, David

2011-01-01

"Keeping Up with the Steins" (2006) is the first Hollywood film to focus on the Bar Mitzvah ceremony in its family, congregational, and Jewish community context. The film demonstrates how popular culture reflects community values, but may also shape them. The hero is alienated both from the synagogue service and his mega-Bar Mitzvah party. In line…

Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM).

PubMed

Xiong, Kai; Zhou, Yan; Hyttel, Poul; Bolund, Lars; Freude, Kristine Karla; Luo, Yonglun

2016-11-01

Human fibroblasts were engineered to express the CRISPR-based synergistic activation mediator (SAM) complex: dCas9-VP64 and MS2-P65-HSF1. Two induced pluripotent stem cells (iPSCs) clones expressing SAM were established by transducing these fibroblasts with lentivirus expressing OCT4, SOX2, KLF4 and C-MYC. We have validated that the reprogramming cassette is silenced in the SAM iPSC clones. Expression of pluripotency genes (OCT4, SOX2, LIN28A, NANOG, GDF3, SSEA4, and TRA-1-60), differentiation potential to all three germ layers, and normal karyotypes are validated. These SAM-iPSCs provide a novel, useful tool to investigate genetic regulation of stem cell proliferation and differentiation through CRISPR-mediated activation of endogenous genes. Copyright © 2016 Michael Boutros, German Cancer Research Center, Heidelberg, Germany. Published by Elsevier B.V. All rights reserved.

3 CFR 8943 - Proclamation 8943 of March 25, 2013. Establishment of the Harriet Tubman-Underground Railroad...

Code of Federal Regulations, 2014 CFR

2014-01-01

... a Methodist congregation. Later, in the mid-19th century, African Americans split off from the... Underground Railroad. It is representative of the landscape of this region in the early and mid-19th century... Stat. 225, 16 U.S.C. 431) (the “Antiquities Act”), authorizes the President, in his discretion, to...

Sex Ed...And the Reds? Reconsidering the Anaheim Battle over Sex Education, 1962-1969

ERIC Educational Resources Information Center

Mehlman, Natalia

2007-01-01

By December 1968, the Anaheim Family Life and Sex Education (FLSE) program, celebrated since its formal introduction in 1965 as one of the most progressive in the nation, was being smeared as communistic and perverse. Local activists in this Orange County city had been congregating in hotel rooms and homes, screening cautionary films for the…

A Student Sleuth Haunts the Grounds where a College Once Burned

ERIC Educational Resources Information Center

Biemiller, Lawrence

2009-01-01

On the 224th anniversary of the laying of Cokesbury College's cornerstone, Bonnie J. McCubbin drove to the little church that was once the institution's chapel and told the congregation that she might have solved a two-centuries-old mystery: Who set the fire that destroyed the pioneering Methodist college one December night in 1795? Ms. McCubbin,…

Staff Stress and Morale in Community-Based Settings for People with Intellectual Disabilities and Challenging Behaviour: A Brief Report

ERIC Educational Resources Information Center

Robertson, Janet; Hatton, Chris; Felce, David; Meek, Andrea; Carr, Deborah; Knapp, Martin; Hallam, Angela; Emerson, Eric; Pinkney, Lisa; Caesar, Emma; Lowe, Kathy

2005-01-01

Background: There are no studies that have compared outcomes for staff in different types of supported accommodation for people with intellectual disabilities and challenging behaviour. This study looked at stress, morale and intended job turnover in staff in two types of community-based residential supports: non-congregate settings where the…

New Partners in Jewish Education: Independent Afterschool Jewish Education Programs and Their Relationships with Congregational Supplementary Schools

ERIC Educational Resources Information Center

Novak Winer, Laura

2017-01-01

In recent years the Jewish community has witnessed a growth in the development of Jewish afterschool programs that provide childcare as well as Jewish educational programming to elementary age children. This possible trend may represent a diversification of options for families seeking to provide Jewish education and Jewish experiences for their…

"To Save Their Substance That They May Live Together": Rethinking Schooling and Literacy in Eighteenth-Century Algonquian Communities in Southern New England

ERIC Educational Resources Information Center

Rice, Alanna

2010-01-01

In this article, the author talks about schooling and the development of literacy within Algonquian communities in eighteenth-century southern New England. With the founding of Moor's Indian Charity School in Lebanon, Connecticut, in 1754, congregational minister Eleazar Wheelock launched an educational regimen that aimed to Christianize and…

The Discernment Process of the Sisters of Saint Dominic regarding the Continued Sponsorship of Its Secondary Schools

ERIC Educational Resources Information Center

Tavis, Patricia

2010-01-01

The purpose of this dissertation was to examine the factors that a congregation of women religious, the Sisters of Saint Dominic of Caldwell, New Jersey, must consider in order to continue its sponsored relationship and the extent of this sponsored relationship with its secondary educational ministries for the future. This descriptive and…

Relocating People with Intellectual Disability to New Accommodation and Support Settings: Contrasts between Personalized Arrangements and Group Home Placements

ERIC Educational Resources Information Center

McConkey, Roy; Keogh, Fiona; Bunting, Brendan; Garcia Iriarte, Edurne; Watson, Sheelah Flatman

2016-01-01

Internationally the relocation of people with intellectual disability from institutions has brought significant gains to their quality of life. This study contrasted three groups of persons in Ireland who moved either to personalized arrangements (n = 29) or to community group homes (n = 31) with those who remained in congregated settings awaiting…

How Pastors and Their Spouses Give Meaning to Their Experiences as Clergy Families

ERIC Educational Resources Information Center

Gunter, Glendon Todd

2011-01-01

Clergy are often the first people parishioners will turn to for help in times of trouble. They and their families have unique positions in the congregation. The sense of call in combination with what some researchers have called stressors, are all part of the experience of clergy and their families. Quantitative researchers have identified some…

The "Flavor" of the Social Ecology Paradigm in Use: Building on Mutual Social Support in Preventing Drug Abuse.

ERIC Educational Resources Information Center

Thorsheim, Howard I.; Roberts, Bruce B.

The "Bottled Pain" project, a drug abuse prevention program in 24 Lutheran congregations in southern Minnesota, is based on a social ecology paradigm designed to prevent drug abuse through the development of socially supportive relationshps and through using the environment as a natural strength within the community. According to the…

Academic Skills Rovers: A Just in Time Peer Support Initiative for Academic Skills and Literacy Development

ERIC Educational Resources Information Center

Copeman, Peter; Keightley, Polly

2014-01-01

In 2013 the University of Canberra (UC) initiated a program of peer-assisted academic skills help, the Academic Skills Rovers program, with the goal of providing drop-in peer learning support to students at campus locations where they congregate to study. The Academic Skills Rovers were initially recruited from the teacher education discipline,…

Causes of Hunger: A User's Guide for Christian Congregations. Companion Guide to Causes of Hunger: Hunger 1995.

ERIC Educational Resources Information Center

Park, Susan Kay; Simmons, Jim

This document is an interactive, intergenerational guide designed to help organize group or individual study of "Causes of Hunger." The guide includes activities, worship aids, Bible studies, and a resource list--all adapted for classes, weekend retreats, and evening meetings. The guide is divided into nine sessions to be used with a variety of…

What People Want, Why They Move, and What Happens After They Move: A Summary of Research in Retirement Housing.

ERIC Educational Resources Information Center

Parr, Joyce; And Others

This document presents an overview of research in retirement housing which focuses on studying individuals' adaptation to retirement housing, consulting on the design of retirement housing, and conducting community surveys to assess the interest in living options for older persons. The terms congregate housing, continuing care retirement centers,…

CEIST: The First 10 Years of a Lay Catholic Educational Trust in Ireland

ERIC Educational Resources Information Center

Griffin, Marie

2018-01-01

In the first half of 2007, Catholic Education an Irish Schools Trust (CEIST) was established when several Religious Congregations handed trusteeship of their schools to a lay company. As CEIST--in the Irish language the word 'CEIST' means 'question'--completes 10 years serving the needs of its 110 secondary schools, it seems an appropriate time to…

Assessing and Mobilizing Faith Organizations to Implement Childhood Obesity Prevention Advocacy Strategies.

PubMed

Bozlak, Christine T; Kenady, James M; Becker, Adam B

2018-01-01

Childhood obesity remains a public health problem requiring mobilization across diverse social and political sectors. The faith-based sector can contribute to obesity prevention advocacy when existing resources are supported and leveraged. This article describes an advocacy resource assessment conducted in six Chicago faith organizations. Key administrators and congregation members were surveyed to identify organizational resources that could be mobilized for childhood obesity prevention advocacy. Survey data were analyzed using SPSS and Excel. Descriptive statistics were calculated for each organization and for all combined. Organizational resources for advocacy were identified, with varying degrees of resources within organizations. Congregation members and faith leaders expressed interest in advocacy training and activities but acknowledged competing organizational priorities. Participating organizations received a stipend to pursue recommended action items based on their assessment. Faith organizations have unique resources and human capital and can be key partners in childhood obesity prevention. Conducting an assessment prior to planning interventions and advocacy approaches can strengthen partnerships, leverage assets among partners, and ensure efforts are relevant and beneficial for faith organizations. It may also be strategic to incorporate funding in grant budgets in order to empower faith organizations to act on findings from the assessment process.

Changes in Church-Based Social Support Relationships During Older Adulthood

PubMed Central

2013-01-01

Objectives. To track the course of age-related changes in emotional and tangible support given and received by older adults in the context of their religious congregations. Method. Hierarchical linear modeling was applied to data from a national sample of 1,192 White and African American older adults who attended church regularly, and they were interviewed up to four times over a period of seven years. Results. Changes were found in six measures of support. Participants increased in terms of the amount of emotional support that they both gave and received, whereas decreased in the amount of tangible support they gave and received. Satisfaction increased with age for both emotional and tangible support. There were large race-related differences, with African Americans being more engaged in support relationships of all types. Religious factors, including frequency of attendance, commitment, and the congregational cohesiveness were strong predictors of between-person differences. Discussion. This study is the first to demonstrate within-person change in church-based support relationships during the course of older adulthood. Patterns of increasing quantity and quality of emotional ties, but decreasing tangible support, partially contrast with previous findings regarding secular support networks but are consistent with the socioemotional selectivity perspective. PMID:23149429

Analysis on the Oversize Blast Furnace Desulfurization and a Sulfide Capacity Prediction Model Based on Congregated Electron Phase

NASA Astrophysics Data System (ADS)

Zhenyang, Wang; Jianliang, Zhang; Gang, An; Zhengjian, Liu; Zhengming, Cheng; Junjie, Huang; Jingwei, Zhang

2016-02-01

Through analyzed and regressed the actual productive desulfurization data from the oversize blast furnace (5500 m3) in north China, the relationship between the sulfur distribution parameters and the slag composition in actual production situation was investigated. As the slag and hot metal phases have their own balance sulfur content or sulfur partial pressure in gas phase, respectively, the non-equilibrium of sulfur among gas, slag, and metal phases leads to the transmission and distribution of sulfur. Combined with sulfur transmission reactions between gas, slag and metal phases, C/CO pairs equilibrium, and Wagner model, the measured sulfide capacity can be acquired using sulfur distribution ratio, sulfur activity coefficient, and oxygen activity in hot metal. Based on the theory of congregated electron phase, a new sulfide capacity prediction model (CEPM) has been developed, which has a good liner relationship with the measured sulfide capacity. Thus, using the burden structure for BF, the ironmaking slag composition can be obtained simply and can be used to reliably predict the ironmaking slag desulfurization ability a few hours later after charging under a certain temperature by CEPM.

Outbreeding and lack of temporal genetic structure in a drone congregation of the neotropical stingless bee Scaptotrigona mexicana

PubMed Central

Mueller, Matthias Y; Moritz, Robin FA; Kraus, F Bernhard

2012-01-01

Drone aggregations are a widespread phenomenon in many stingless bee species (Meliponini), but the ultimate and proximate causes for their formation are still not well understood. One adaptive explanation for this phenomenon is the avoidance of inbreeding, which is especially detrimental for stingless bees due to the combined effects of the complementary sex-determining system and the small effective population size caused by eusociality and monandry. We analyzed the temporal genetic dynamics of a drone aggregation of the stingless bee Scaptotrigona mexicana with microsatellite markers over a time window of four weeks. We estimated the drones of the aggregation to originate from a total of 55 colonies using sibship re-construction. There was no detectable temporal genetic differentiation or sub-structuring in the aggregation. Most important, we could exclude all colonies in close proximity of the aggregation as origin of the drones in the aggregation, implicating that they originate from more distant colonies. We conclude that the diverse genetic composition and the distant origin of the drones of the S. mexicana drone congregation provides an effective mechanism to avoid mating among close relatives. PMID:22833802

Outbreeding and lack of temporal genetic structure in a drone congregation of the neotropical stingless bee Scaptotrigona mexicana.

PubMed

Mueller, Matthias Y; Moritz, Robin Fa; Kraus, F Bernhard

2012-06-01

Drone aggregations are a widespread phenomenon in many stingless bee species (Meliponini), but the ultimate and proximate causes for their formation are still not well understood. One adaptive explanation for this phenomenon is the avoidance of inbreeding, which is especially detrimental for stingless bees due to the combined effects of the complementary sex-determining system and the small effective population size caused by eusociality and monandry. We analyzed the temporal genetic dynamics of a drone aggregation of the stingless bee Scaptotrigona mexicana with microsatellite markers over a time window of four weeks. We estimated the drones of the aggregation to originate from a total of 55 colonies using sibship re-construction. There was no detectable temporal genetic differentiation or sub-structuring in the aggregation. Most important, we could exclude all colonies in close proximity of the aggregation as origin of the drones in the aggregation, implicating that they originate from more distant colonies. We conclude that the diverse genetic composition and the distant origin of the drones of the S. mexicana drone congregation provides an effective mechanism to avoid mating among close relatives.

Pastor and Lay Leader Perceptions of Barriers and Supports to HIV Ministry Maintenance in an African American Church

PubMed Central

2013-01-01

Abstract Clergy and lay leaders have a pivotal role in the development and maintenance of HIV Ministries within the African American church. However, little is known about the actual roles these men and women have, the barriers they face and the supports they have found in the development and maintenance of an HIV Ministry. The purpose of this study is to examine the role, barriers and supports clergy and lay leaders experienced in the development of a long-standing HIV ministry in an African American church. These data were gathered from a larger ethnographic study, which examined the role of religious culture in the development, implementation and maintenance of an HIV ministry. Data for this study were collected through in-depth semi-structured interviews. Results revealed that the primary role of clergy and lay leaders involved dispelling myths surrounding HIV and ensuring congregational support. The primary barrier to the development and maintenance was views regarding sexuality. The primary support was their relationships with congregants that lived with HIV and AIDS. This information can assist in developing interventions to enhance the African American church movement toward HIV ministries. PMID:22870846

Pastor and lay leader perceptions of barriers and supports to HIV ministry maintenance in an African American church.

PubMed

Stewart, Jennifer M

2014-04-01

Clergy and lay leaders have a pivotal role in the development and maintenance of HIV Ministries within the African American church. However, little is known about the actual roles these men and women have, the barriers they face and the supports they have found in the development and maintenance of an HIV Ministry. The purpose of this study is to examine the role, barriers and supports clergy and lay leaders experienced in the development of a long-standing HIV ministry in an African American church. These data were gathered from a larger ethnographic study, which examined the role of religious culture in the development, implementation and maintenance of an HIV ministry. Data for this study were collected through in-depth semi-structured interviews. Results revealed that the primary role of clergy and lay leaders involved dispelling myths surrounding HIV and ensuring congregational support. The primary barrier to the development and maintenance was views regarding sexuality. The primary support was their relationships with congregants that lived with HIV and AIDS. This information can assist in developing interventions to enhance the African American church movement toward HIV ministries.

At-sea detection of marine debris: overview of technologies, processes, issues, and options.

PubMed

Mace, Thomas H

2012-01-01

At-sea detection of marine debris presents a difficult problem, as the debris items are often relatively small and partially submerged. However, they may accumulate in water parcel boundaries or eddy lines. The application of models, satellite radar and multispectral data, and airborne remote sensing (particularly radar) to focus the search on eddies and convergence zones in the open ocean appear to be a productive avenue of investigation. A multistage modeling and remote sensing approach is proposed for the identification of areas of the open ocean where debris items are more likely to congregate. A path forward may best be achieved through the refinement of the Ghost Net procedures with the addition of a final search stage using airborne radar from an UAS simulator aircraft to detect zones of potential accumulation for direct search. Sampling strategies, direct versus indirect measurements, remote sensing resolution, sensor/platform considerations, and future state are addressed. Copyright © 2011 Elsevier Ltd. All rights reserved.

Effects of a Pilot Church-based Intervention to Reduce HIV Stigma and Promote HIV Testing among African Americans and Latinos

PubMed Central

Derose, Kathryn P.; Griffin, Beth Ann; Kanouse, David E.; Bogart, Laura M.; Williams, Malcolm V.; Haas, Ann C.; Flórez, Karen R.; Collins, Deborah Owens; Hawes-Dawson, Jennifer; Mata, Michael A.; Oden, Clyde W.; Stucky, Brian D.

2016-01-01

HIV-related stigma and mistrust contribute to HIV disparities. Addressing stigma with faith partners may be effective, but few church-based stigma reduction interventions have been tested. We implemented a pilot intervention with 3 Latino and 2 African American churches (4 in matched pairs) in high HIV prevalence areas of Los Angeles County to reduce HIV stigma and mistrust and increase HIV testing. The intervention included HIV education and peer leader workshops, pastor-delivered sermons on HIV with imagined contact scenarios, and HIV testing events. We surveyed congregants at baseline and 6 month follow-up (n=1235) and found statistically significant (p<.05) reductions in HIV stigma and mistrust in the Latino intervention churches but not in the African American intervention church nor overall across matched African American and Latino pairs. However, within matched pairs, intervention churches had much higher rates of HIV testing (p< .001). Stigma reduction and HIV testing may have synergistic effects in community settings. PMID:27000144

KSC-2014-2071

NASA Image and Video Library

2014-04-13

CAPE CANAVERAL, Fla. - Members of the winning teams in the International Space Apps Challenge display their Galactic Problem Solver certificates. From left are SpaceWear team members Keith Hargett and Alejandro Velasco, and Astronaut Resource Managing System team members Roberto Ricci, Sam Neblett, and James Brucato. Caley Burke, the NASA event organizer lead, is at right. Kennedy Space Center hosted one of the over 90 locations around the world where participants congregated for the attempt to design innovative solutions for global challenges over a 48-hour period. This year's development marathon focused on five NASA mission areas: Asteroids, Earth Watch, Human Spaceflight, Robotics, and Technology in Space. Three of this year’s challenges were developed by KSC employees: Space Wearables: Fashion Designer to Astronauts, Growing Food for a Martian Table, and Asteroid Prospector. The winners selected in 2014 at Kennedy were Astronaut Resource Managing System, or ARMS, for Best Use of Data and SpaceWear for Best Use of Hardware. ARMS also took the People's Choice Award. For more information, visit https://2014.spaceappschallenge.org. Photo credit: NASA/Daniel Casper

KSC-2014-2067

NASA Image and Video Library

2014-04-13

CAPE CANAVERAL, Fla. - Astronaut Resource Managing System team members Sam Neblett of KSC Technik Inc., left, and Roberto Ricci participate in the International Space Apps Challenge in the Center for Space Education at the Kennedy Space Center Visitor Complex in Florida. Kennedy Space Center hosted one of the over 90 locations around the world where participants congregated for the attempt to design innovative solutions for global challenges over a 48-hour period. This year's development marathon focused on five NASA mission areas: Asteroids, Earth Watch, Human Spaceflight, Robotics, and Technology in Space. Three of this year’s challenges were developed by KSC employees: Space Wearables: Fashion Designer to Astronauts, Growing Food for a Martian Table, and Asteroid Prospector. The winners selected in 2014 at Kennedy were Astronaut Resource Managing System, or ARMS, for Best Use of Data and SpaceWear for Best Use of Hardware. ARMS also took the People's Choice Award. For more information, visit https://2014.spaceappschallenge.org. Photo credit: NASA/Daniel Casper

KSC-2014-2070

NASA Image and Video Library

2014-04-13

CAPE CANAVERAL, Fla. - SpaceWear team members Keith Hargett, left, and Alejandro Velasco demonstrate their entry in the International Space Apps Challenge to NASA Ground Systems Development and Operation Program Manager Michael Bolger and NASA's Lisa Singleton in the Center for Space Education at the Kennedy Space Center Visitor Complex in Florida. Kennedy Space Center hosted one of the over 90 locations around the world where participants congregated for the attempt to design innovative solutions for global challenges over a 48-hour period. This year's development marathon focused on five NASA mission areas: Asteroids, Earth Watch, Human Spaceflight, Robotics, and Technology in Space. Three of this year’s challenges were developed by KSC employees: Space Wearables: Fashion Designer to Astronauts, Growing Food for a Martian Table, and Asteroid Prospector. The winners selected in 2014 at Kennedy were Astronaut Resource Managing System, or ARMS, for Best Use of Data and SpaceWear for Best Use of Hardware. ARMS also took the People's Choice Award. For more information, visit https://2014.spaceappschallenge.org. Photo credit: NASA/Daniel Casper

The Third Therapeutic System: Faith Healing Strategies in the Context of a Generalized AIDS Epidemic

PubMed Central

Manglos, Nicolette D.; Trinitapoli, Jenny

2014-01-01

Faith healing in sub-Saharan Africa has primarily been studied qualitatively among Pentecostal-Charismatic groups, and considered as its own phenomenon with little attention to its relationship to other modes of healing. Using data from Malawi, a religiously diverse African country with high HIV prevalence, we find that faith healing is pervasive across multiple religious traditions. For individuals, attending a faith healing congregation is associated with lower levels of generalized worry about AIDS, and this association is driven by those who switched churches before AIDS became widespread in rural areas. Use of condoms and traditional medicine are, on the other hand, positively associated with worry about AIDS. We argue that faith healing can be understood as a third therapeutic system that coexists with the well-documented biomedical and traditional systems. The success of faith healing approaches lies in their unique ability to combine individual-pragmatic and communal-ritualized aspects of healing to inform interpretations of the AIDS epidemic and its consequences. PMID:21362615

Reduced West Nile Virus Transmission Around Communal Roosts of Great-Tailed Grackle (Quiscalus mexicanus)

PubMed Central

Komar, Nicholas; Colborn, James M.; Horiuchi, Kalanthe; Delorey, Mark; Biggerstaff, Brad; Damian, Dan; Smith, Kirk; Townsend, John

2016-01-01

West Nile virus has caused several outbreaks among humans in the Phoenix metropolitan area (Arizona, southwest USA) within the last decade. Recent ecologic studies have implicated Culex quinquefasciatus and Culex tarsalis as the mosquito vectors and identified three abundant passerine birds—great-tailed grackle (Quiscalus mexicanus), house sparrow (Passer domesticus), and house finch (Haemorhous mexicanus)—as key amplifiers among vertebrates. Nocturnal congregations of certain species have been suggested as critical for late summer West Nile virus amplification. We evaluated the hypothesis that house sparrow (P. domesticus) and/or great-tailed grackle (Q. mexicanus) communal roost sites (n = 22 and n = 5, respectively) in a primarily suburban environment were spatially associated with West Nile virus transmission indices during the 2010 outbreak of human neurological disease in metropolitan Phoenix. Spatial associations between human case residences and communal roosts were non-significant for house sparrows, and were negative for great-tailed grackle. Several theories that explain these observations are discussed, including the possibility that grackle communal roosts are protective. PMID:25480320

Changing with the times to keep the meaning of mission.

PubMed

Schuster, J; Thomas, J M

1988-06-01

In the fall of 1987, the Franciscan Sisters of the Poor Health System, Inc. (HSI), took over Madison Square Garden's Felt Forum to hold a fund-raiser. Called the Franciscan Health Care Games, the weekend-long event pitted employees from 14 HSI facilities against one another in basketball and volleyball tournaments; featured 40 stars of film, television, and the sports world in competition; and ended with a gala dinner for 950 people. The event, a first for the Franciscans, raised $800,000. Some of the programs the money will benefit include: The Young Fathers Project, a program in Cincinnati that helps fathers between the ages of 16 and 21 adjust to being a parent. Eldercare, which provides health services to some 5,000 elderly patients at 13 congregate housing sites throughout the Columbus, OH, area. The St. Elizabeth Medical Center in Dayton, OH, which helps support services at a hotel for the homeless sponsored by St. Vincent de Paul Society.

The application of ultraviolet germicidal irradiation to control transmission of airborne disease: bioterrorism countermeasure.

PubMed

Brickner, Philip W; Vincent, Richard L; First, Melvin; Nardell, Edward; Murray, Megan; Kaufman, Will

2003-01-01

Bioterrorism is an area of increasing public health concern. The intent of this article is to review the air cleansing technologies available to protect building occupants from the intentional release of bioterror agents into congregate spaces (such as offices, schools, auditoriums, and transportation centers), as well as through outside air intakes and by way of recirculation air ducts. Current available technologies include increased ventilation, filtration, and ultraviolet germicidal irradiation (UVGI) UVGI is a common tool in laboratories and health care facilities, but is not familiar to the public, or to some heating, ventilation, and air conditioning engineers. Interest in UVGI is increasing as concern about a possible malicious release of bioterror agents mounts. Recent applications of UVGI have focused on control of tuberculosis transmission, but a wide range of airborne respiratory pathogens are susceptible to deactivation by UVGI. In this article, the authors provide an overview of air disinfection technologies, and an in-depth analysis of UVGI-its history, applications, and effectiveness.

Exploring the Influence of Environment on the Spatial Behavior of Older Adults in a Purpose-Built Acute Care Dementia Unit.

PubMed

Mazzei, Francesco; Gillan, Roslyn; Cloutier, Denise

2014-06-01

Limited research explores the experience of individuals with dementia in acute care geriatric psychiatry units. This observational case study examines the influence of the physical environment on behavior (wandering, pacing, door testing, congregation and seclusions) among residents in a traditional geriatric psychiatry unit who were then relocated to a purpose-built acute care unit. Purpose-built environments should be well suited to the needs of residents with dementia. Observed trends revealed differences in spatial behaviors in the pre- and post- environments attributable to the physical environment. Person-centred modifications to the current environment including concerted efforts to know residents are meaningful in fostering quality of life. Color coded environments (rooms vs dining areas etc.) to improve wayfinding and opportunities to personalize rooms that address the `hominess' of the setting also have potential. Future research could also seek the opinions of staff about the impact of the environment on them as well as residents. © The Author(s) 2013.

Community-based telemonitoring for hypertension management: practical challenges and potential solutions.

PubMed

Hovey, Lauren; Kaylor, Mary Beth; Alwan, Majd; Resnick, Helaine E

2011-10-01

Older adults residing in rural areas often lack convenient, patient-centered, community-based approaches to facilitate receipt of routine care to manage common chronic conditions. Without adequate access to appropriate disease management resources, the risk of seniors' experiencing acute events related to these common conditions increases substantially. Further, poorly managed chronic conditions are costly and place seniors at increased risk of institutionalization and permanent loss of independence. Novel, telehealth-based approaches to management of common chronic conditions like hypertension may not only improve the health of older adults, but may also lead to substantial cost savings associated with acute care episodes and institutionalization. The aim of this report is to summarize practical considerations related to operations and logistics of a unique community-based telemonitoring pilot study targeting rural seniors who utilize community-based senior centers. This article reviews the technological challenges encountered during the study and proposes solutions relevant to future research and implementation of telehealth in community-based, congregate settings.

Wenig gesehen, selten anerkannt … - Das Engagement muslimischer Gemeinden in der Flüchtlingsintegration

NASA Astrophysics Data System (ADS)

Deuter, Marie-Sophie; Mantel, Anna; Engel, Susen

2018-03-01

Focussing on the invisibility of a muslim congregation in Altena (Westf) concerning their civic engagement for refugees and integration, we can show that different actors within civil urban society are being unequally addressed and supported. Our empirical material reveals a normative framing of the recognition and appreciation of civic engagement that corresponds to tendencies of middle class anti-Muslim Racism.

The Role of Support Staff as People Move from Congregated Settings to Group Homes and Personalized Arrangements in Ireland

ERIC Educational Resources Information Center

García Iriarte, Edurne; Stockdale, Janine; McConkey, Roy; Keogh, Fiona

2016-01-01

The movement of people with intellectual disabilities into the community is increasingly endorsed by public policy. Whilst staff are critical to a successful transition to the community, there is only scattered research on their role in supporting people to move. In this study, 32 staff and the 16 people with intellectual disabilities they…

Encouraging Word: The Pastor's Role in Increasing Biblical Literacy in the Local Congregation

ERIC Educational Resources Information Center

Leach, Todd A.

2016-01-01

The Bible has long been valued and esteemed as the primary text for Christians all over the world. It tells the story of God and of the Christian faith and it provides guidance for Christians on how to live faithfully for Jesus Christ. Thus, one would expect a knowledge and understanding of the Bible to be a high priority--of utmost…

Getting the Books Off the Shelves. Making the Most of Your Congregation's Library. Second Revised Edition. CSLA Guide No. 12.

ERIC Educational Resources Information Center

Smith, Ruth S.

This second revised edition of a guide to promoting and attracting users to a church library retains most of the material of the previous edition, adds new material, and updates the references. Guidelines are presented in six chapters: (1) "Promoting Library Use" (stages of promotion, ways of attracting the attention and interest of prospective…

The effect of topography, vegetation, and weather on cattle distribution at the San Joaquin Experimental Range, California

Treesearch

Norman R. Harris; Douglas E. Johnson; Melvin R. George; Neil K. McDougald

2002-01-01

In this study livestock distribution on the landscape was mapped during two seasons, summer and winter, for two years to determine where livestock congregate and to model factors that influence livestock distribution. Two small herds of cows were observed in separate range units on the San Joaquin Experimental Range for a total of twenty-four 24-hour observation...

Wenig gesehen, selten anerkannt …. Das Engagement muslimischer Gemeinden in der Flüchtlingsintegration

NASA Astrophysics Data System (ADS)

Deuter, Marie-Sophie; Mantel, Anna; Engel, Susen

2018-04-01

Focussing on the invisibility of a muslim congregation in Altena (Westf) concerning their civic engagement for refugees and integration, we can show that different actors within civil urban society are being unequally addressed and supported. Our empirical material reveals a normative framing of the recognition and appreciation of civic engagement that corresponds to tendencies of middle class anti-Muslim Racism.

The role of religious leaders in promoting acceptance of vaccination within a minority group: a qualitative study

PubMed Central

2013-01-01

Background Although childhood vaccination programs have been very successful, vaccination coverage in minority groups may be considerably lower than in the general population. In order to increase vaccination coverage in such minority groups involvement of faith-based organizations and religious leaders has been advocated. We assessed the role of religious leaders in promoting acceptance or refusal of vaccination within an orthodox Protestant minority group with low vaccination coverage in The Netherlands. Methods Semi-structured interviews were conducted with orthodox Protestant religious leaders from various denominations, who were selected via purposeful sampling. Transcripts of the interviews were thematically analyzed, and emerging concepts were assessed for consistency using the constant comparative method from grounded theory. Results Data saturation was reached after 12 interviews. Three subgroups of religious leaders stood out: those who fully accepted vaccination and did not address the subject, those who had religious objections to vaccination but focused on a deliberate choice, and those who had religious objections to vaccination and preached against vaccination. The various approaches of the religious leaders seemed to be determined by the acceptance of vaccination in their congregation as well as by their personal point of view. All religious leaders emphasized the importance of voluntary vaccination programs and religious exemptions from vaccination requirements. In case of an epidemic of a vaccine preventable disease, they would appreciate a dialogue with the authorities. However, they were not willing to promote vaccination on behalf of authorities. Conclusion Religious leaders’ attitudes towards vaccination vary from full acceptance to clear refusal. According to orthodox Protestant church order, local congregation members appoint their religious leaders themselves. Obviously they choose leaders whose views are compatible with the views of the congregation members. Moreover, the positions of orthodox Protestant religious leaders on vaccination will not change easily, as their objections to vaccination are rooted in religious doctrine and they owe their authority to their interpretation and application of this doctrine. Although the dialogue with religious leaders that is pursued by the Dutch government may be helpful in controlling epidemics by other means than vaccination, it is unlikely to increase vaccination coverage. PMID:23711160

The role of religious leaders in promoting acceptance of vaccination within a minority group: a qualitative study.

PubMed

Ruijs, Wilhelmina L M; Hautvast, Jeannine L A; Kerrar, Said; van der Velden, Koos; Hulscher, Marlies E J L

2013-05-28

Although childhood vaccination programs have been very successful, vaccination coverage in minority groups may be considerably lower than in the general population. In order to increase vaccination coverage in such minority groups involvement of faith-based organizations and religious leaders has been advocated. We assessed the role of religious leaders in promoting acceptance or refusal of vaccination within an orthodox Protestant minority group with low vaccination coverage in The Netherlands. Semi-structured interviews were conducted with orthodox Protestant religious leaders from various denominations, who were selected via purposeful sampling. Transcripts of the interviews were thematically analyzed, and emerging concepts were assessed for consistency using the constant comparative method from grounded theory. Data saturation was reached after 12 interviews. Three subgroups of religious leaders stood out: those who fully accepted vaccination and did not address the subject, those who had religious objections to vaccination but focused on a deliberate choice, and those who had religious objections to vaccination and preached against vaccination. The various approaches of the religious leaders seemed to be determined by the acceptance of vaccination in their congregation as well as by their personal point of view. All religious leaders emphasized the importance of voluntary vaccination programs and religious exemptions from vaccination requirements. In case of an epidemic of a vaccine preventable disease, they would appreciate a dialogue with the authorities. However, they were not willing to promote vaccination on behalf of authorities. Religious leaders' attitudes towards vaccination vary from full acceptance to clear refusal. According to orthodox Protestant church order, local congregation members appoint their religious leaders themselves. Obviously they choose leaders whose views are compatible with the views of the congregation members. Moreover, the positions of orthodox Protestant religious leaders on vaccination will not change easily, as their objections to vaccination are rooted in religious doctrine and they owe their authority to their interpretation and application of this doctrine. Although the dialogue with religious leaders that is pursued by the Dutch government may be helpful in controlling epidemics by other means than vaccination, it is unlikely to increase vaccination coverage.

Variation by Age in Parish Involvement Scores of Catholic Church Attenders in Australia, New Zealand and the United States: Age Effect or Generational Effect?

ERIC Educational Resources Information Center

Dixon, Robert

2006-01-01

This article examines levels of involvement of weekly church attenders in Catholic parishes in Australia, New Zealand and the United States through an analysis of data from the International Congregational Life Survey. Factor analysis was used to identify four questionnaire items related to parish involvement which were then combined to produce a…

Criminal Provisions of the Clean Air Act Amendments of 1990 and their Interface with the United States Sentencing Guidelines

DTIC Science & Technology

1991-09-30

it appears no other thing to me than a foul and pestilent congregation of vapors." Hamlet , Act II, Scene 229 "We will not turn our backs or look the... Shakespeare Selected Plays 210 (1981). (30) Remarks on Signing the Bill Amending the Clean Air Act, 26 Weekly Comp. Pres. Doc. 1823 (Nov. 15, 1990). (31

Removing the Stigma: For God and Country

DTIC Science & Technology

2013-03-01

Virginians to the Puritans. George Washington exemplified the sentiments of our founding fathers in his response to the address from the Hebrew Congregation...distribution of Bibles 18 to the Japanese people. He declared, “We must have ten thousand Christian missionaries and a million bibles to complete the...crosses and Christian messages were painted on military vehicles driving through Iraq; images of U.S. soldiers holding rifles and bibles were posted on

Spiritual and Religious Supports Part 10: Congruence in Faith and Action--Inclusivity in New Orleans

ERIC Educational Resources Information Center

Johnson, Alan

2010-01-01

The First Congregational Church has a heart of mission. Yet, when the mission hits a situation that's personal and makes one squirm a bit, it becomes more of a challenge. Seven teams have been sent from the church to help the rebuilding in New Orleans. The first teams did the mucking, getting all of the belongings out of the house and putting them…

The effect of trance on memory content.

PubMed

Goodman, F D

1975-01-01

In a Yucatecan crisis cult of short duration, the millenary expectations are remembered long after the dissolution of the cult. So is Satan who, it is felt, tempted the congregation. The cultural innovations instituted during the cult, however, are almost immediately forgotten. The differential recall is shown to be related to the quality of the trance behavior during the cult and to the threatening versus neutral content of the memory material.

Mass Media Theory, Leveraging Relationships, and Reliable Strategic Communication Effects

DTIC Science & Technology

2008-03-19

other people who are in the same social and cultural groups. Families respond to patriarchs and matriarchs , congregations respond to pastors, and teens...media to self-correct behavior in order to make society seem more “normal.” Verbal and Written Message- Centric Theories Premise of Theory Magic...Effects Harmony and Balance People gravitate toward information they already believe. Structural Functionalism When society begins to seem

A Study of the Microstructural Basis for the Strength and Toughness Properties of Water-Quenched and Air-Cooled HSLA-100, HSLA-100 with Increased Copper, and a ULCB Steel

DTIC Science & Technology

1991-09-01

martensite . Howell reported previously the presence of polygonal ferrite and copper precipitates in... copper precipitates were found throughout the acicular ferrite and martensite laths; most frequently decorating dislocations. The precipitates congregated...evidently precipitate out into the transformation products; resulting in the observed e- copper precipitates . These small, ductile particles lead

The Effect of Immigration on Religious Belief and Practice: A Theologizing or Alienating Experience?

PubMed

Massey, Douglas S; Higgins, Monica Espinoza

2011-09-01

Using data from the New Immigrant Survey, we examine the religious beliefs and practices of new legal immigrants to the United States. We find that Christian immigrants are more Catholic, more Orthodox, and less Protestant than American Christians, and that those immigrants who are Protestant are more likely to be evangelical. In addition to being more Catholic and more Orthodox than American Christians, the new immigrants are also paradoxically less Christian, with a fifth reporting some other faith. Detailed analysis of reported church attendance at places of origin and in the United States suggest that immigration is a disruptive event that alienates immigrants from religious practice rather than "theologizing" them. In addition, our models clearly show that people who join congregations in the United States are highly selected and unrepresentative of the broader population of immigrants in any faith. In general, congregational members were more observant both before and after emigration, were more educated, had more cumulative experience in the United States, and were more likely to have children present in the household and be homeowners and therefore yield biased representations of all adherents to any faith. The degree of selectivity and hence bias also varies markedly both by religion and nationality.

Colour preference and light sensitivity in trilobite larvae of mangrove horseshoe crab, Carcinoscopius rotundicauda (Latreille, 1802).

PubMed

Srijayat, T C; Pradeep, P J; Hassan, A; Chatterji, A; Shaharom, F; Jeffs, Andrew

2014-03-01

The trilobite larvae of C. rotundicauda were tested to determine their colour preference and light sensitivity until their first moulting (25 days post hatching) under laboratory conditions. Maximum congregation size of the trilobite larvae was found in the white zone respectively where (n = 12) followed by yellow (n = 8) and orange (n = 8), which showed the larval preference for lighter zones. Morisita's index calculation showed a clumped/aggregated distribution (yellow, blue, orange and white) and uniform/hyper dispersed distribution (green, red and black) for various colours tested. Trilobite larvae showed least preference for brighter regions while tested in the experiment [black; (n = 4) and red; (n = 5)]. Experiments done to determine the light sensitivity of trilobite larvae showed that the larvae had more preference towards ultraviolet lights. The maximum congregation size of 38.8 and 40.7% of the larvae was encountered under ultraviolet light, when the light sources were kept horizontal and vertical, respectively. Overall, results suggested that the trilobite larvae of C. rotundicauda, preferred light source of shorter wavelengths (UV light) and colours of lighter zone (white, yellow, orange), which might be due to their adaptation to their natural habitat for predator avoidance, prey selection and water quality.

The Effect of Immigration on Religious Belief and Practice: A Theologizing or Alienating Experience?

PubMed Central

Massey, Douglas S.; Higgins, Monica Espinoza

2010-01-01

Using data from the New Immigrant Survey, we examine the religious beliefs and practices of new legal immigrants to the United States. We find that Christian immigrants are more Catholic, more Orthodox, and less Protestant than American Christians, and that those immigrants who are Protestant are more likely to be evangelical. In addition to being more Catholic and more Orthodox than American Christians, the new immigrants are also paradoxically less Christian, with a fifth reporting some other faith. Detailed analysis of reported church attendance at places of origin and in the United States suggest that immigration is a disruptive event that alienates immigrants from religious practice rather than “theologizing” them. In addition, our models clearly show that people who join congregations in the United States are highly selected and unrepresentative of the broader population of immigrants in any faith. In general, congregational members were more observant both before and after emigration, were more educated, had more cumulative experience in the United States, and were more likely to have children present in the household and be homeowners and therefore yield biased representations of all adherents to any faith. The degree of selectivity and hence bias also varies markedly both by religion and nationality. PMID:23606773

Child Protection Investigations in Out-of-Home Care: Perpetrators, Victims, and Contexts.

PubMed

Font, Sarah A

2015-11-01

Keeping children safe in out-of-home care requires an understanding of the contexts under which maltreatment occurs. This study examines how maltreatment investigations differ across four settings (nonrelative foster, informal kinship, formal kinship, and congregate care). I focus on four elements of maltreatment: the perpetrator's role (e.g., out-of-home caregiver and peer), maltreatment type, probability of substantiation, and victim characteristics. I use statewide Wisconsin administrative data in years 2005-2012, which has an analytic sample of over 96,000 placements. Data are analyzed using descriptive statistics and multi-level logistic regression. Alleged maltreatment is not uncommon in out-of-home care-the total investigation rate ranged from 5% (congregate care) to 15% (informal kinship care). Four percent of all placements were investigated for maltreatment by an out-of-home caregiver, of which 9% were substantiated. Maltreatment by peers (siblings or other foster children) was investigated in 1% of all placements, of which 20% were substantiated. Neglect was the most commonly alleged maltreatment type in informal kinship care, whereas physical abuse was most commonly alleged in all other placement types. Children who were female, Black, or between ages 6 and 10 experienced heightened risk of maltreatment in out-of-home care. © The Author(s) 2015.

Child Protection Investigations in Out-of-Home Care: Perpetrators, Victims, and Contexts

PubMed Central

Font, Sarah A.

2015-01-01

Keeping children safe in out-of-home care requires an understanding of the contexts under which maltreatment occurs. This study examines how maltreatment investigations differ across four settings (nonrelative foster, informal kinship, formal kinship, and congregate care). I focus on four elements of maltreatment: the perpetrator’s role (e.g., out-of-home caregiver and peer), maltreatment type, probability of substantiation, and victim characteristics. I use statewide Wisconsin administrative data in years 2005–2012, which has an analytic sample of over 96,000 placements. Data are analyzed using descriptive statistics and multi-level logistic regression. Alleged maltreatment is not uncommon in out-of-home care—the total investigation rate ranged from 5% (congregate care) to 15% (informal kinship care). Four percent of all placements were investigated for maltreatment by an out-of-home caregiver, of which 9% were substantiated. Maltreatment by peers (siblings or other foster children) was investigated in 1% of all placements, of which 20% were substantiated. Neglect was the most commonly alleged maltreatment type in informal kinship care, whereas physical abuse was most commonly alleged in all other placement types. Children who were female, Black, or between ages 6 and 10 experienced heightened risk of maltreatment in out-of-home care. PMID:26224743

Contextual influences on participation in community organizing: a multilevel longitudinal study.

PubMed

Christens, Brian D; Speer, Paul W

2011-06-01

This article reports results from a study of contextual influences on participation among people involved in congregation-based community organizing. Data are drawn from 11,538 individual participants in 115 congregations taking part in one of five local organizing initiatives in different cities over a five-year period. Analyses used 3-level longitudinal models with binary indicators of participation/non-participation in group meetings each successive year as the criterion. Time-varying predictors at level-1 included prior participation in group meetings as a control, the types of group meetings that participants attended, the number of face-to-face meetings held between each participant and organizing staff of the local organizing initiatives, and a measure of the involvement of participants' affiliation networks. At level-2, demographic information was collected for a subset of participants (N = 461) and was included in a separate model. Neighborhood compositional characteristics were examined at level-3, including median income, economic heterogeneity, and residential stability. Study results found that characteristics of organizational settings (i.e., types of group meetings attended and frequency of face-to-face contact) predicted future participation in group meetings but that individual and neighborhood-level demographic characteristics were generally not predictive of future participation in community organizing activities.

{open_quotes}In close proximity{close_quotes} to E&P waste management facilities: Lessons of three communities in the Four Corners Area

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shuey, C.

1994-12-31

Contaminant releases from E&P waste management facilities located near residences in three communities in the Four Corners Area -- two in New Mexico and one in Utah -- spurred vocal concern among local residents in recent years. Noxious odors, including hydrogen sulfide, were present in all cases and releases of production wastes and oil spills were prevalent in two of the cases. In all three, residents said they felt powerless to change operator or agency decisions about siting of facilities close to places where people congregate. These cases illustrate the need for regulators to consider facility locations in permitting decisions.more » They also demonstrate the need for creation of statutorily recognized buffer zones around new oil and gas production and processing facilities where releases of pollutants to the air, land and water can reasonably be expected, regardless of the level of pollution control. Buffer zones may be especially important in states where local governments have not elected to adopt land use and zoning requirements that affect the siting of E&P facilities. Agency and corporate sensitivity to siting concerns will engender public confidence in permitting decisions and avoid the needless waste of public and private resources.« less

Digital logic circuits in yeast with CRISPR-dCas9 NOR gates

PubMed Central

Gander, Miles W.; Vrana, Justin D.; Voje, William E.; Carothers, James M.; Klavins, Eric

2017-01-01

Natural genetic circuits enable cells to make sophisticated digital decisions. Building equally complex synthetic circuits in eukaryotes remains difficult, however, because commonly used components leak transcriptionally, do not arbitrarily interconnect or do not have digital responses. Here, we designed dCas9-Mxi1-based NOR gates in Saccharomyces cerevisiae that allow arbitrary connectivity and large genetic circuits. Because we used the chromatin remodeller Mxi1, our gates showed minimal leak and digital responses. We built a combinatorial library of NOR gates that directly convert guide RNA (gRNA) inputs into gRNA outputs, enabling the gates to be ‘wired' together. We constructed logic circuits with up to seven gRNAs, including repression cascades with up to seven layers. Modelling predicted the NOR gates have effectively zero transcriptional leak explaining the limited signal degradation in the circuits. Our approach enabled the largest, eukaryotic gene circuits to date and will form the basis for large, synthetic, cellular decision-making systems. PMID:28541304

RNA editing with CRISPR-Cas13.

PubMed

Cox, David B T; Gootenberg, Jonathan S; Abudayyeh, Omar O; Franklin, Brian; Kellner, Max J; Joung, Julia; Zhang, Feng

2017-11-24

Nucleic acid editing holds promise for treating genetic disease, particularly at the RNA level, where disease-relevant sequences can be rescued to yield functional protein products. Type VI CRISPR-Cas systems contain the programmable single-effector RNA-guided ribonuclease Cas13. We profiled type VI systems in order to engineer a Cas13 ortholog capable of robust knockdown and demonstrated RNA editing by using catalytically inactive Cas13 (dCas13) to direct adenosine-to-inosine deaminase activity by ADAR2 (adenosine deaminase acting on RNA type 2) to transcripts in mammalian cells. This system, referred to as RNA Editing for Programmable A to I Replacement (REPAIR), which has no strict sequence constraints, can be used to edit full-length transcripts containing pathogenic mutations. We further engineered this system to create a high-specificity variant and minimized the system to facilitate viral delivery. REPAIR presents a promising RNA-editing platform with broad applicability for research, therapeutics, and biotechnology. Copyright © 2017, American Association for the Advancement of Science.

RNA Editing with CRISPR-Cas13

PubMed Central

Cox, David B.T.; Gootenberg, Jonathan S.; Abudayyeh, Omar O.; Franklin, Brian; Kellner, Max J.; Joung, Julia; Zhang, Feng

2017-01-01

Nucleic acid editing holds promise for treating genetic disease, particularly at the RNA level, where disease-relevant sequences can be rescued to yield functional protein products. Type VI CRISPR-Cas systems contain the programmable single-effector RNA-guided RNases Cas13. Here, we profile Type VI systems to engineer a Cas13 ortholog capable of robust knockdown and demonstrate RNA editing by using catalytically-inactive Cas13 (dCas13) to direct adenosine to inosine deaminase activity by ADAR2 to transcripts in mammalian cells. This system, referred to as RNA Editing for Programmable A to I Replacement (REPAIR), has no strict sequence constraints, can be used to edit full-length transcripts containing pathogenic mutations. We further engineer this system to create a high specificity variant, REPAIRv2, that is 919 times more specific than REPAIRv1 as well as minimize the system to ease viral delivery. REPAIR presents a promising RNA editing platform with broad applicability for research, therapeutics, and biotechnology. PMID:29070703

Duckweed in bloom: the 2nd International Conference on Duckweed Research and Applications heralds the return of a plant model for plant biology.

PubMed

Lam, Eric; Appenroth, Klaus J; Michael, Todd; Mori, Kazuhiro; Fakhoorian, Tamra

2014-04-01

More than 50 participants from around the world congregated at Rutgers University for 4 days to discuss the latest advances in duckweed research and applications. Among other developments in the field, exciting new information related to duckweed including genome sequencing, improved genetic transformation, and the identification of a novel plant growth promoting substance from bacteria were reported.

Unbalanced Stability: Applying Lessons from American Cities in Stability Operations

DTIC Science & Technology

2011-05-19

teenagers congregating on street corners, public solicitation for prostitution, begging, public drinking, verbal harassment of women on the street, and...United Nations Security Council, “United Nations Security Council Resolution 1590 (2005).” http://www.un.org/ga/search/view_doc.asp?symbol=S/RES/ 1590 (2005...Security Council. “United Nations Security Council Resolution 1590 (2005).” United Nations. http://www.un.org/ga/search/view_doc.asp?symbol=S/RES/ 1590

Benchmark and Framework for Encouraging Research on Multi-Threaded Testing Tools

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Stoller, Scott D.; Ur, Shmuel

2003-01-01

A problem that has been getting prominence in testing is that of looking for intermittent bugs. Multi-threaded code is becoming very common, mostly on the server side. As there is no silver bullet solution, research focuses on a variety of partial solutions. In this paper (invited by PADTAD 2003) we outline a proposed project to facilitate research. The project goals are as follows. The first goal is to create a benchmark that can be used to evaluate different solutions. The benchmark, apart from containing programs with documented bugs, will include other artifacts, such as traces, that are useful for evaluating some of the technologies. The second goal is to create a set of tools with open API s that can be used to check ideas without building a large system. For example an instrumentor will be available, that could be used to test temporal noise making heuristics. The third goal is to create a focus for the research in this area around which a community of people who try to solve similar problems with different techniques, could congregate.

Fetal Membranes-Derived Stem Cells Microenvironment.

PubMed

Favaron, Phelipe Oliveira; Miglino, Maria Angelica

2017-01-01

Recently, the regenerative medicine has been trying to congregate different areas such as tissue engineering and cellular therapy, in order to offer effective treatments to overcome several human and veterinary medical problems. In this regard, fetal membranes have been proposed as a powerful source for obtainment of multipotent stem cells with low immunogenicity, anti-inflammatory properties and nontumorigenicity properties for the treatment of several diseases, including replacing cells lost due to tissue injuries or degenerative diseases. Morpho-physiological data have shown that fetal membranes, especially the yolk sac and amnion play different functions according to the gestational period, which are direct related to the features of the microenvironment that their cells are subject. The characteristics of the microenvironment affect or controls important cellular events involved with proliferation, division and maintenance of the undifferentiated stage or differentiation, especially acting on the extracellular matrix components. Considering the importance of the microenvironment and the diversity of embryonic and fetal membrane-derived stem cells, this chapter will addressed advances in the isolation, phenotyping, characteristics of the microenvironment, and applications of yolk sac and amniotic membrane-derived stem cells for human and veterinary regenerative medicine.

Reduced West Nile Virus Transmission Around Communal Roosts of Great-Tailed Grackle (Quiscalus mexicanus).

PubMed

Komar, Nicholas; Colborn, James M; Horiuchi, Kalanthe; Delorey, Mark; Biggerstaff, Brad; Damian, Dan; Smith, Kirk; Townsend, John

2015-03-01

West Nile virus has caused several outbreaks among humans in the Phoenix metropolitan area (Arizona, southwest USA) within the last decade. Recent ecologic studies have implicated Culex quinquefasciatus and Culex tarsalis as the mosquito vectors and identified three abundant passerine birds-great-tailed grackle (Quiscalus mexicanus), house sparrow (Passer domesticus), and house finch (Haemorhous mexicanus)-as key amplifiers among vertebrates. Nocturnal congregations of certain species have been suggested as critical for late summer West Nile virus amplification. We evaluated the hypothesis that house sparrow (P. domesticus) and/or great-tailed grackle (Q. mexicanus) communal roost sites (n = 22 and n = 5, respectively) in a primarily suburban environment were spatially associated with West Nile virus transmission indices during the 2010 outbreak of human neurological disease in metropolitan Phoenix. Spatial associations between human case residences and communal roosts were non-significant for house sparrows, and were negative for great-tailed grackle. Several theories that explain these observations are discussed, including the possibility that grackle communal roosts are protective.

KSC-2014-2069

NASA Image and Video Library

2014-04-13

CAPE CANAVERAL, Fla. - SpaceWear team members Keith Hargett, left, and Alejandro Velasco explain their entry in the International Space Apps Challenge to an audience in the Center for Space Education at the Kennedy Space Center Visitor Complex in Florida. In the audience at left is NASA Ground Systems Development and Operations Program Manager Michael Bolger. Caley Burke, the NASA event organizer lead, is at right. Kennedy Space Center hosted one of the over 90 locations around the world where participants congregated for the attempt to design innovative solutions for global challenges over a 48-hour period. This year's development marathon focused on five NASA mission areas: Asteroids, Earth Watch, Human Spaceflight, Robotics, and Technology in Space. Three of this year’s challenges were developed by KSC employees: Space Wearables: Fashion Designer to Astronauts, Growing Food for a Martian Table, and Asteroid Prospector. The winners selected in 2014 at Kennedy were Astronaut Resource Managing System, or ARMS, for Best Use of Data and SpaceWear for Best Use of Hardware. ARMS also took the People's Choice Award. For more information, visit https://2014.spaceappschallenge.org. Photo credit: NASA/Daniel Casper

Assessing the Congregate Disaster Shelter: Using Shelter Facility Assessment Data for Evaluating Potential Hazards to Occupants During Disasters.

PubMed

Cruz, Miguel A; Garcia, Stephanie; Chowdhury, Muhammad A B; Malilay, Josephine; Perea, Nancy; Williams, O Dale

Disaster shelter assessments are environmental health assessments conducted during disaster situations to evaluate the living environment of shelters for hygiene, sanitation, and safety conditions. We conducted a secondary data analysis of shelter assessment records available (n = 108) on ice storms, floods, and tornado events from 1 state jurisdiction. Descriptive statistics were used to analyze results of environmental health deficiencies found in the facilities. The greater numbers of environmental health deficiencies were associated with sanitation (26%), facility physical issues (19%), and food areas (17%). Most deficiencies were reported following ice storms, tornadoes, and flood events. This report describes the first analysis of environmental health deficiencies found in disaster shelters across a spectrum of disaster events. Although the number of records analyzed for this project was small and results may not be generalizable, this new insight into the living environment in shelter facilities offers the first analysis of deficiencies of the shelter operation and living environment that have great potential to affect the safety and health of shelter occupants.

Access to and use of health services among undocumented Mexican immigrants in a US urban area.

PubMed

Nandi, Arijit; Galea, Sandro; Lopez, Gerald; Nandi, Vijay; Strongarone, Stacey; Ompad, Danielle C

2008-11-01

We assessed access to and use of health services among Mexican-born undocumented immigrants living in New York City in 2004. We used venue-based sampling to recruit participants from locations where undocumented immigrants were likely to congregate. Participants were 18 years or older, born in Mexico, and current residents of New York City. The main outcome measures were health insurance coverage, access to a regular health care provider, and emergency department care. In multivariable models, living in a residence with fewer other adults, linguistic acculturation, higher levels of formal income, higher levels of social support, and poor health were associated with health insurance coverage. Female gender, fewer children, arrival before 1997, higher levels of formal income, health insurance coverage, greater social support, and not reporting discrimination were associated with access to a regular health care provider. Higher levels of education, higher levels of formal income, and poor health were associated with emergency department care. Absent large-scale political solutions to the challenges of undocumented immigrants, policies that address factors shown to limit access to care may improve health among this growing population.

Sodium dietary restriction, knowledge, beliefs, and decision-making behavior of older females.

PubMed

Sheahan, Sharon L; Fields, Becky

2008-04-01

The purposes of this qualitative/descriptive study were to (a) explore experiences and decision-making behaviors associated with adoption of a sodium-restricted diet (SRD) among older women with hypertension or heart failure and (b) identify healthcare system and contextual factors that facilitate or impede adherence to SRD. Participants were 33 single older women, aged 65-98 years, residing in three congregate living facilities in the high-risk "coronary valley" area of the United States. A semistructured interview format was employed with three focus groups. The audio-taped transcribed data were content analyzed for themes by the researchers with the assistance of ATLAS.Ti computer software. Predominant themes were lack of SRD education by healthcare providers, a desire for more information about sodium, including the use of alternative herbal seasonings, and large-print informational materials. Eating alone with no motivation to cook and share meals was a contextual barrier to healthy nutrition. To prevent costly hospitalizations and rehospitalization from nonadherence to SRD, clinicians need to provide more structured SRD education supplemented with printed brochures. Exploring the client's nutritional social setting may improve SRD adherence.

Effects of a Pilot Church-Based Intervention to Reduce HIV Stigma and Promote HIV Testing Among African Americans and Latinos.

PubMed

Derose, Kathryn P; Griffin, Beth Ann; Kanouse, David E; Bogart, Laura M; Williams, Malcolm V; Haas, Ann C; Flórez, Karen R; Collins, Deborah Owens; Hawes-Dawson, Jennifer; Mata, Michael A; Oden, Clyde W; Stucky, Brian D

2016-08-01

HIV-related stigma and mistrust contribute to HIV disparities. Addressing stigma with faith partners may be effective, but few church-based stigma reduction interventions have been tested. We implemented a pilot intervention with 3 Latino and 2 African American churches (4 in matched pairs) in high HIV prevalence areas of Los Angeles County to reduce HIV stigma and mistrust and increase HIV testing. The intervention included HIV education and peer leader workshops, pastor-delivered sermons on HIV with imagined contact scenarios, and HIV testing events. We surveyed congregants at baseline and 6 month follow-up (n = 1235) and found statistically significant (p < 0.05) reductions in HIV stigma and mistrust in the Latino intervention churches but not in the African American intervention church nor overall across matched African American and Latino pairs. However, within matched pairs, intervention churches had much higher rates of HIV testing (p < 0.001). Stigma reduction and HIV testing may have synergistic effects in community settings.

A wax ester promotes collective host finding in the nematode Pristionchus pacificus.

PubMed

Penkov, Sider; Ogawa, Akira; Schmidt, Ulrike; Tate, Dhananjay; Zagoriy, Vyacheslav; Boland, Sebastian; Gruner, Margit; Vorkel, Daniela; Verbavatz, Jean-Marc; Sommer, Ralf J; Knölker, Hans-Joachim; Kurzchalia, Teymuras V

2014-04-01

Survival of nematode species depends on how successfully they disperse in the habitat and find a new host. As a new strategy for collective host finding in the nematode Pristionchus pacificus, dauer larvae synthesize an extremely long-chain polyunsaturated wax ester (nematoil) that covers the surface of the animal. The oily coat promotes congregation of up to one thousand individuals into stable 'dauer towers' that can reach a beetle host more easily.

Final Environmental Assessment: Construction of SWMU 74 Groundwater Extraction and Convenience System Arnold Air Force Base, Tennessee

DTIC Science & Technology

2004-08-01

winter when birds migrate from the north. Most of the birds congregate during the winter at Reelfoot Lake and Dale Hollow Reservoir, but bald eagles...streams (USDA Soil Conservation Service, 1949). 3.1.2 Hydrology Hydrological features include surface waters ( lakes , rivers, streams, and springs) and...Fahrenheit (Smith, 2004). Precipitation is fairly evenly distributed throughout the year, with slightly Woods Reservoir Normandy Lake Tims Ford LakeRock

Final Environmental Assessment: Evaluation of J-85-5 Engine Test Burn

DTIC Science & Technology

2005-01-01

is highest in winter when birds migrate from the north. Most of the birds congregate during the winter at Reelfoot Lake and Dale Hollow Reservoir...Hydrological features include surface waters ( lakes , rivers, streams, and springs) and groundwater. Arnold AFB lies within the Duck River and the Elk...Smaller creeks R ow la nd C re ek Crumpton Creek Sinking Pond Woods Reservoir Normandy Lake Tims Ford Lake Retention Reservoir Duck River Figure 3-1 0

Freedom of Religion and Conscience in the Military: Clarifying Policy

DTIC Science & Technology

2013-04-01

curriculum which included Bible reading and a Christian hymnal in the District of Columbia schools, as well as other acts by the early Congresses...regard in his “Letter to the Hebrew Congregation in Newport, Rhode Island” (August 18, 1790), a copy of which is still on display in that...Establishment Clause.97 The Court considered another landmark case only one year later when on an eight-to-one vote it struck down Bible reading in public

Embryo adoption: Some further considerations

PubMed Central

Patterson, Colin

2015-01-01

Recent discussions of embryo adoption have sought to make sense of the teaching of the Congregation for the Doctrine of the Faith (CDF) document Dignitas personae which appeared to provide a negative judgment on such a practice. This article aims to provide a personalist account of the process of fertilization and implantation that might serve as the basis for the negative judgment of the CDF document. In doing so, it relies upon the idea that a person, including an embryo, is not to be considered in isolation, but always in relation to God and to others. This approach extends the substantialist conceptualizations commonly employed in discussions of this issue. More generally, the article seeks to highlight the value of a personalist re-framing for an understanding of the moral questions surrounding the beginning of life. Lay summary: This article seeks to make sense of what appears to be a clear-cut rejection, set out in the Congregation for the Doctrine of the Faith (CDF) document Dignitas personae, of the proposal for women to “adopt” surplus frozen embryos. It draws upon more recently developed modes of philosophical/theological reasoning to argue that, in human procreation, both fertilization and implantation represent constitutive dimensions of divine creative activity and so must be protected from manipulative technological intervention. Since embryo adoption requires this kind of technology, it makes sense for the Church document not to approve it. PMID:25698841

Embryo adoption: Some further considerations.

PubMed

Patterson, Colin

2015-02-01

Recent discussions of embryo adoption have sought to make sense of the teaching of the Congregation for the Doctrine of the Faith (CDF) document Dignitas personae which appeared to provide a negative judgment on such a practice. This article aims to provide a personalist account of the process of fertilization and implantation that might serve as the basis for the negative judgment of the CDF document. In doing so, it relies upon the idea that a person, including an embryo, is not to be considered in isolation, but always in relation to God and to others. This approach extends the substantialist conceptualizations commonly employed in discussions of this issue. More generally, the article seeks to highlight the value of a personalist re-framing for an understanding of the moral questions surrounding the beginning of life. Lay summary: This article seeks to make sense of what appears to be a clear-cut rejection, set out in the Congregation for the Doctrine of the Faith (CDF) document Dignitas personae, of the proposal for women to "adopt" surplus frozen embryos. It draws upon more recently developed modes of philosophical/theological reasoning to argue that, in human procreation, both fertilization and implantation represent constitutive dimensions of divine creative activity and so must be protected from manipulative technological intervention. Since embryo adoption requires this kind of technology, it makes sense for the Church document not to approve it.

Changing and Differentiated Urban Landscape in China: Spatiotemporal Patterns and Driving Forces.

PubMed

Fang, Chuanglin; Li, Guangdong; Wang, Shaojian

2016-03-01

Urban landscape spatiotemporal change patterns and their driving mechanisms in China are poorly understood at the national level. Here we used remote sensing data, landscape metrics, and a spatial econometric model to characterize the spatiotemporal patterns of urban landscape change and investigate its driving forces in China between 1990 and 2005. The results showed that the urban landscape pattern has experienced drastic changes over the past 15 years. Total urban area has expanded approximately 1.61 times, with a 2.98% annual urban-growth rate. Compared to previous single-city studies, although urban areas are expanding rapidly, the overall fragmentation of the urban landscape is decreasing and is more irregular and complex at the national level. We also found a stair-stepping, urban-landscape changing pattern among eastern, central, and western counties. In addition, administrative level, urban size, and hierarchy have effects on the urban landscape pattern. We also found that a combination of landscape metrics can be used to supplement our understanding of the pattern of urbanization. The changes in these metrics are correlated with geographical indicators, socioeconomic factors, infrastructure variables, administrative level factors, policy factors, and historical factors. Our results indicate that the top priority should be strengthening the management of urban planning. A compact and congregate urban landscape may be a good choice of pattern for urban development in China.

Ocean in Motion

NASA Technical Reports Server (NTRS)

1999-01-01

Under a data purchase agreement with Goddard Space Flight Center, Orbital Sciences Corporation has been able to contract building of the Sea-Viewing Wide-Field-of-View Sensor (SeaWIFS). Orbital Sciences was then able commercialized the data that the satellite produces. These data are used to create daily fish finding maps, allowing fishing fleets to focus on locations where many commercially important surface feeding fish, like tuna and swordfish, congregate. In agriculture and forestry, SeaWIFS' images offer an alternative to direct on-site inspection or expensive serial photography.

National study of public spending for mental retardation and developmental disabilities.

PubMed

Braddock, D; Hemp, R; Fujiura, G

1987-09-01

Results of a nationwide study of public mental retardation/developmental disabilities (MR/DD) spending in the states during Fiscal Years 1977 through 1986 were summarized. Trends identified included: (a) continuing growth in spending for community services, (b) contraction of total spending for institutional operations, and (c) predominance of ICF/MR support in large (16+ beds) congregate care settings. Periodic replication of the study was recommended as was additional research to identify the political and economic determinants of state MR/DD spending.

[Health, illnes and higiene in the boarding schools. the case of the salesian arts and craft scholl of Córdoba. 1905 - 1930].

PubMed

Moretti, Nicolás

2017-01-01

The following article asks about the speeches, practices, representations and experiences on health, hygiene and illnes in boarding schools early last century, taking for instance the School of Arts and Crafts of the Salesian Congregation, with the intention of revisiting the dialogue between medicine, hygiene and school in the context of development of the social question, the result of accelerated modernization process experienced by the city of Córdoba.

Inter- and Intra- Field variations in soil compaction levels and subsequent impacts on hydrological extremes

NASA Astrophysics Data System (ADS)

Pattison, Ian; Coates, Victoria

2015-04-01

The rural landscape in the UK is dominated by pastoral agriculture, with about 40% of land cover classified as either improved or semi-natural grassland according to the Land Cover Map 2007. Intensification has resulted in greater levels of compaction associated with higher stocking densities. However, there is likely to be a great amount of variability in compaction levels within and between fields due to multiple controlling factors. This research focusses in on two of these factors; firstly animal species, namely sheep, cattle and horses; and secondly field zonation e.g. feeding areas, field gates, open field. Field experiments have been conducted in multiple fields in the River Skell catchment, in Yorkshire, UK, which has an area of 140km2. The effect on physical and hydrologic soil characteristics such as bulk density and moisture contents have been quantified using a wide range of field and laboratory based experiments. Results have highlighted statistically different properties between heavily compacted areas where animals congregate and less-trampled open areas. Furthermore, soil compaction has been hypothesised to contribute to increased flood risk at larger spatial scales. Previous research (Pattison, 2011) on a ~40km2 catchment (Dacre Beck, Lake District, UK) has shown that when soil characteristics are homogeneously parameterised in a hydrological model, downstream peak discharges can be 65% higher for a heavy compacted soil than for a lightly compacted soil. Here we report results from spatially distributed hydrological modelling using soil parameters gained from the field experimentation. Results highlight the importance of both the percentage of the catchment which is heavily compacted and also the spatial distribution of these fields.

The role of livestock-poached pasture as a sediment source

NASA Astrophysics Data System (ADS)

Greenwood, Philip; Walling, Desmond; Quine, Timothy

2015-04-01

Historically, the occurrence of sediment-laden runoff has almost exclusively been associated with cultivated hillslopes and particularly with arable land. This association was commonly accompanied by the presumption that, in comparison with cultivated slopes, erosion from intensively-managed lowland pasture was relatively low. Recent developments in sediment source tracing and fingerprinting techniques have, however, challenged these assumptions by demonstrating that soil loss from grasslands may be greater than previously assumed. In attempting to identify potential source areas within grassland environments, attention has frequently focused on areas of livestock poaching where herd animals tend to congregate. However, the role of poached grassland as a sediment-source remains uncertain. Reasons include the difficulties associated with accurately documenting the movement or redistribution of small quantities of fine sediment over relevant spatial and temporal scales. Motivated by an urgent need for such information, this communication presents preliminary results from a tracing study aimed at measuring sediment redistribution within areas of poached pasture over short (i.e. event-based) timescales using the artificial radionuclides, caesium-134 (134Cs) and cobalt-60 (60Co). The approach involved labelling six small areas (0.2 * 0.2 m) of poached soil, each with a contrasting gradient, with either 134Cs or 60Co, and then measuring changes in the radiometric inventory at predetermined points before and after periods of rainfall. Each labelled area of poached pasture was measured on three separate occasions over a 65 day period. At the end of the monitoring phase, the mean net soil redistribution depth (mm) was negative for all plots, with values ranging from -6.8 mm to -15.2 mm. This is interpreted as evidence of the removal, or erosion, of surface material. The findings indicate that areas of livestock-poached pasture can act as significant sediment sources. These findings are discussed with regard to the potential contribution of poaching to the off-site transfer of fine-sediment from affected grasslands, and to the implications for the water quality of receiving streams.

Resident and proprietor perspectives on a recovery orientation in community-based housing.

PubMed

Piat, Myra; Boyer, Richard; Fleury, Marie-Josée; Lesage, Alain; O'Connell, Maria; Sabetti, Judith

2015-03-01

Stable housing is a fundamental human right, and an important element for both mental health recovery and social inclusion among people with serious mental illness. This article reports findings from a study on the recovery orientation of structured congregate community housing services using the Recovery Self-Assessment Questionnaire (RSA) adapted for housing (O'Connell, Tondora, Croog, Evans, & Davidson, 2005). The RSA questionnaires were administered to 118 residents and housing providers from 112 congregate housing units located in Montreal, Canada. Residents rated their homes as significantly less recovery-oriented than did proprietors, which is contrary to previous studies of clinical services or Assertive Community Treatment where RSA scores for service users were significantly higher than service provider scores. Findings for both groups suggest the need for improvement on 5 of 6 RSA factors. While proprietors favored recovery training and education, and valued resident opinion and experience, vestiges of a traditional medical model governing this housing emerged in other findings, as in agreement between the 2 groups that residents have little choice in case management, or in the belief among proprietors that residents are unable to manage their symptoms. This study demonstrates that the RSA adapted for housing is a useful tool for creating recovery profiles of housing services. The findings provide practical guidance on how to promote a recovery orientation in structured community housing, as well as a novel approach for reaching a common understanding of what this entails among stakeholders. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

Resident and Proprietor Perspectives of a Recovery Orientation in Community-Based Housing

PubMed Central

Piat, Myra; Boyer, Richard; Fleury, Marie-Josée; Lesage, Alain; O’Connell, Maria; Sabetti, Judith

2016-01-01

Objective Stable housing is a fundamental human right, and an important element for both mental health recovery and social inclusion among people with serious mental illness. This article reports findings from a study on the recovery orientation of structured congregate community housing services using the Recovery Self-Assessment Questionnaire (RSA) adapted for housing (O’Connell, Tondora, Croog, Evans, & Davidson, 2005). Methods The RSA questionnaires were administered to 118 residents and housing providers from 112 congregate housing units located in Montreal, Canada. Results Residents rated their homes as significantly less recovery-oriented than did proprietors, which is contrary to previous studies of clinical services or Assertive Community Treatment where RSA scores for service users were significantly higher than service provider scores. Findings for both groups suggest the need for improvement on 5 of 6 RSA factors. While proprietors favored recovery training and education, and valued resident opinion and experience, vestiges of a traditional medical model governing this housing emerged in other findings, as in agreement between the 2 groups that residents have little choice in case management, or in the belief among proprietors that residents are unable to manage their symptoms. Conclusions and Implications for Practice This study demonstrates that the RSA adapted for housing is a useful tool for creating recovery profiles of housing services. The findings provide practical guidance on how to promote a recovery orientation in structured community housing, as well as a novel approach for reaching a common understanding of what this entails among stakeholders. PMID:25559078

Housing First Improves Adherence to Antipsychotic Medication Among Formerly Homeless Adults With Schizophrenia: Results of a Randomized Controlled Trial

PubMed Central

Moniruzzaman, Akm; Fazel, Seena; McCandless, Lawrence; Procyshyn, Ric; Somers, Julian M.

2017-01-01

Abstract Adherence to antipsychotic medication is a significant challenge among homeless patients. No experimental trials have investigated the impact of Housing First on adherence among patients with schizophrenia. We investigated whether Housing First in congregate and scattered-site configurations resulted in superior adherence compared to usual care. Adult participants (n = 165) met criteria for homelessness, schizophrenia, and initiation of antipsychotic pharmacotherapy prior to recruitment to an unblinded, 3-arm randomized controlled trial in Vancouver, Canada. Randomization arms were: congregate Housing First (CHF) with on-site supports (including physician and pharmacy services); scattered-site Housing First (SHF) with Assertive Community Treatment; or treatment as usual (TAU) consisting of existing services. Participants were followed for an average of 2.6 years. Adherence to antipsychotic medication was measured using the medication possession ratio (MPR), and 1-way ANOVA was used to compare outcomes between the 3 conditions. Data were drawn from comprehensive pharmacy records. Prior to randomization, mean MPR among participants was very low (0.44–0.48). Mean MPR in the follow-up period was significantly different between study arms (P < .001) and approached the guideline threshold of 0.80 in SHF. Compared to TAU, antipsychotic adherence was significantly higher in SHF but not in CHF. The results demonstrate that further implementation of SHF is indicated among homeless people with schizophrenia, and that urgent action is needed to address very low levels of antipsychotic adherence in this population (trial registration: ISRCTN57595077). PMID:27665002

Subthreshold depression: characteristics and risk factors among vulnerable elders.

PubMed

Adams, Kathryn Betts; Moon, Heehyul

2009-09-01

This study examines symptoms of subthreshold depression among older adults in congregate housing, compared with their nondepressed peers, and tests a conceptual model of subthreshold depression. Hypotheses included that subthreshold depression would be characterized and distinguished by low energy, social withdrawal, and depletion, rather than sadness, and that subthreshold depressed elders would be distinguished by poorer health and functioning, loneliness, and grieving a recent loss. A self-administered survey was followed by a diagnostic interview by telephone to (N = 166) white and African-American residents of independent and assisted living apartments from six retirement communities, average age 82.9 years. The Mini International Neuropsychiatric Interview (MINI) determined depression status. The 30-item Geriatric Depression Scale was used to measure symptoms. Forty-six individuals (27.7%) were identified as subthreshold depressed, seven as suffering from major depression, and 113 as non-depressed. Subthreshold depression was characterized by low energy, difficulty with initiative, worries about the future, lack of positive affect, sadness and irritability. Negative affect symptoms such as sadness and irritability best discriminated the subthreshold group from the nondepressed. Risk factors for subthreshold depression in this sample included less education, lower socio-economic status, African-American race, grieving, and social loneliness. Subthreshold depression in this group of residents of congregate housing was similar to the depletion experienced by many nondepressed elders, but further characterized by negative affect and lack of hope for the future. Social factors, such as socioeconomic status and personal losses, constituted greater risks for subthreshold depression than did health and functioning.

Engaging the community to improve nutrition and physical activity among houses of worship.

PubMed

Evans, Kiameesha R; Hudson, Shawna V

2014-03-13

Obesity, physical inactivity, and poor nutrition have been linked to many chronic diseases. Research indicates that interventions in community-based settings such as houses of worship can build on attendees' trust to address health issues and help them make behavioral changes. New Brunswick, New Jersey, has low rates of physical activity and a high prevalence of obesity. An adapted community-based intervention was implemented there to improve nutrition and physical activity among people who attend houses of worship and expand and enhance the network of partners working with Rutgers Cancer Institute of New Jersey. An adapted version of Body & Soul: A Celebration of Healthy Living and Eating was created using a 3-phase model to 1) educate lay members on nutrition and physical activity, 2) provide sustainable change through the development of physical activity programming, and 3) increase access to local produce through collaborations with community partners. Nineteen houses of worship were selected for participation in this program. Houses of worship provided a questionnaire to a convenience sample of its congregation to assess congregants' physical activity levels and produce consumption behaviors at baseline using questions from the Health Information National Trends Survey instrument. This information was also used to inform future program activities. Community-based health education can be a promising approach when appropriate partnerships are identified, funding is adequate, ongoing information is extracted to inform future action, and there is an expectation from all parties of long-term engagement and capacity building.

Church-based social marketing to motivate older adults to take balance classes for fall prevention: cluster randomized controlled trial.

PubMed

DiGuiseppi, Carolyn G; Thoreson, Sallie R; Clark, Lauren; Goss, Cynthia W; Marosits, Mark J; Currie, Dustin W; Lezotte, Dennis C

2014-10-01

Determine whether a church-based social marketing program increases older adults' participation in balance classes for fall prevention. In 2009-10, 51 churches (7101 total members aged ≥ 60) in Colorado, U.S.A. were randomized to receive no intervention or a social marketing program. The program highlighted benefits of class participation (staying independent, building relationships), reduced potential barriers (providing convenient, subsidized classes), and communicated marketing messages through church leaders, trained "messengers," printed materials and church-based communication channels. Between-group differences in balance class enrollment and marketing message recall among congregants were compared using Wilcoxon Two-Sample Test and regression models. Compared to 25 control churches, 26 churches receiving the social marketing program had a higher median proportion (9.8% vs. 0.3%; p<0.001) and mean number (7.0 vs. 0.5; IRR=11.2 [95%CI: 7.5, 16.8]) of older adult congregants who joined balance classes. Intervention church members were also more likely to recall information about preventing falls with balance classes (AOR=6.2; 95% CI: 2.6, 14.8) and availability of classes locally (AOR=7.7; 95% CI: 2.6, 22.9). Church-based social marketing effectively disseminated messages about preventing falls through balance classes and, by emphasizing benefits and reducing barriers and costs of participation, successfully motivated older adults to enroll in the classes. Copyright © 2014 Elsevier Inc. All rights reserved.

Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism.

PubMed

Schuijers, Jurian; Manteiga, John Colonnese; Weintraub, Abraham Selby; Day, Daniel Sindt; Zamudio, Alicia Viridiana; Hnisz, Denes; Lee, Tong Ihn; Young, Richard Allen

2018-04-10

Transcriptional dysregulation of the MYC oncogene is among the most frequent events in aggressive tumor cells, and this is generally accomplished by acquisition of a super-enhancer somewhere within the 2.8 Mb TAD where MYC resides. We find that these diverse cancer-specific super-enhancers, differing in size and location, interact with the MYC gene through a common and conserved CTCF binding site located 2 kb upstream of the MYC promoter. Genetic perturbation of this enhancer-docking site in tumor cells reduces CTCF binding, super-enhancer interaction, MYC gene expression, and cell proliferation. CTCF binding is highly sensitive to DNA methylation, and this enhancer-docking site, which is hypomethylated in diverse cancers, can be inactivated through epigenetic editing with dCas9-DNMT. Similar enhancer-docking sites occur at other genes, including genes with prominent roles in multiple cancers, suggesting a mechanism by which tumor cell oncogenes can generally hijack enhancers. These results provide insights into mechanisms that allow a single target gene to be regulated by diverse enhancer elements in different cell types. Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

Applications of CRISPR/Cas System to Bacterial Metabolic Engineering.

PubMed

Cho, Suhyung; Shin, Jongoh; Cho, Byung-Kwan

2018-04-05

The clustered regularly interspaced short palindromic repeats/CRISPR-associated (CRISPR/Cas) adaptive immune system has been extensively used for gene editing, including gene deletion, insertion, and replacement in bacterial and eukaryotic cells owing to its simple, rapid, and efficient activities in unprecedented resolution. Furthermore, the CRISPR interference (CRISPRi) system including deactivated Cas9 (dCas9) with inactivated endonuclease activity has been further investigated for regulation of the target gene transiently or constitutively, avoiding cell death by disruption of genome. This review discusses the applications of CRISPR/Cas for genome editing in various bacterial systems and their applications. In particular, CRISPR technology has been used for the production of metabolites of high industrial significance, including biochemical, biofuel, and pharmaceutical products/precursors in bacteria. Here, we focus on methods to increase the productivity and yield/titer scan by controlling metabolic flux through individual or combinatorial use of CRISPR/Cas and CRISPRi systems with introduction of synthetic pathway in industrially common bacteria including Escherichia coli . Further, we discuss additional useful applications of the CRISPR/Cas system, including its use in functional genomics.

Applications of CRISPR/Cas9 in the Mammalian Central Nervous System



PubMed Central

Savell, Katherine E.; Day, Jeremy J.

2017-01-01

Within the central nervous system, gene regulatory mechanisms are crucial regulators of cellular development and function, and dysregulation of these systems is commonly observed in major neuropsychiatric and neurological disorders. However, due to a lack of tools to specifically modulate the genome and epigenome in the central nervous system, many molecular and genetic mechanisms underlying cognitive function and behavior are still unknown. Although genome editing tools have been around for decades, the recent emergence of inexpensive, straightforward, and widely accessible CRISPR/Cas9 systems has led to a revolution in gene editing. The development of the catalytically dead Cas9 (dCas9) expanded this flexibility even further by acting as an anchoring system for fused effector proteins, structural scaffolds, and RNAs. Together, these advances have enabled robust, modular approaches for specific targeting and modification of the local chromatin environment at a single gene. This review highlights these advancements and how the combination of powerful modulatory tools paired with the versatility of CRISPR-Cas9-based systems offer great potential for understanding the underlying genetic and epigenetic contributions of neuronal function, behavior, and neurobiological diseases. PMID:29259522

The Evaluation of a Regional Faith Community Network's Million Hearts Program.

PubMed

Cooper, Jennifer; Zimmerman, Wendy

2016-01-01

The goal of the Million Hearts initiative is to prevent one million heart attacks and strokes by 2017. Maryland was one state in the Association of State and Territorial Health Official's Million Hearts State Learning Collaborative. Washington County, Maryland formed a collaboration between the County Health Department, Meritus Health System, and the Meritus Health Parish Nurse Coordinator to address hypertension in the county. Within a regional network of 52 faith communities, the Parish Nurse Coordinator recruited 25 faith community nurses to participate in a three-month program. Nurses were trained on proper blood pressure measurement and 22 nurses identified 58 participants engaged in blood pressure self-monitoring and coaching for lifestyle changes. Additionally, nurses took 1,729 blood pressures and provided health education to individuals within their congregations. Fifty-one participants participated in blood pressure self-monitoring and lifestyle coaching with faith community nurses. There was improvement in six out of seven lifestyle areas. Eight-two percent of participants (N = 42) decreased their systolic and/or diastolic blood pressure over three months. Coaching provided by faith community nurses can create an environment of sustained support to promote improved lifestyle and blood pressure changes over time. © 2015 Wiley Periodicals, Inc.

Kupffer cells induce Notch-mediated hepatocyte conversion in a common mouse model of intrahepatic cholangiocarcinoma

PubMed Central

Terada, Maiko; Horisawa, Kenichi; Miura, Shizuka; Takashima, Yasuo; Ohkawa, Yasuyuki; Sekiya, Sayaka; Matsuda-Ito, Kanae; Suzuki, Atsushi

2016-01-01

Intrahepatic cholangiocarcinoma (ICC) is a malignant epithelial neoplasm composed of cells resembling cholangiocytes that line the intrahepatic bile ducts in portal areas of the hepatic lobule. Although ICC has been defined as a tumor arising from cholangiocyte transformation, recent evidence from genetic lineage-tracing experiments has indicated that hepatocytes can be a cellular origin of ICC by directly changing their fate to that of biliary lineage cells. Notch signaling has been identified as an essential factor for hepatocyte conversion into biliary lineage cells at the onset of ICC. However, the mechanisms underlying Notch signal activation in hepatocytes remain unclear. Here, using a mouse model of ICC, we found that hepatic macrophages called Kupffer cells transiently congregate around the central veins in the liver and express the Notch ligand Jagged-1 coincident with Notch activation in pericentral hepatocytes. Depletion of Kupffer cells prevents the Notch-mediated cell-fate conversion of hepatocytes to biliary lineage cells, inducing hepatocyte apoptosis and increasing mortality in mice. These findings will be useful for uncovering the pathogenic mechanism of ICC and developing prevenient and therapeutic strategies for this refractory disease. PMID:27698452

Baleen whale infrasonic sounds: Natural variability and function

NASA Astrophysics Data System (ADS)

Clark, Christopher W.

2004-05-01

Blue and fin whales (Balaenoptera musculus and B. physalus) produce very intense, long, patterned sequences of infrasonic sounds. The acoustic characteristics of these sounds suggest strong selection for signals optimized for very long-range propagation in the deep ocean as first hypothesized by Payne and Webb in 1971. This hypothesis has been partially validated by very long-range detections using hydrophone arrays in deep water. Humpback songs recorded in deep water contain units in the 20-l00 Hz range, and these relatively simple song components are detectable out to many hundreds of miles. The mid-winter peak in the occurrence of 20-Hz fin whale sounds led Watkins to hypothesize a reproductive function similar to humpback (Megaptera novaeangliae) song, and by default this function has been extended to blue whale songs. More recent evidence shows that blue and fin whales produce infrasonic calls in high latitudes during the feeding season, and that singing is associated with areas of high productivity where females congregate to feed. Acoustic sampling over broad spatial and temporal scales for baleen species is revealing higher geographic and seasonal variability in the low-frequency vocal behaviors than previously reported, suggesting that present explanations for baleen whale sounds are too simplistic.

Granular self-organization by autotuning of friction.

PubMed

Kumar, Deepak; Nitsure, Nitin; Bhattacharya, S; Ghosh, Shankar

2015-09-15

A monolayer of granular spheres in a cylindrical vial, driven continuously by an orbital shaker and subjected to a symmetric confining centrifugal potential, self-organizes to form a distinctively asymmetric structure which occupies only the rear half-space. It is marked by a sharp leading edge at the potential minimum and a curved rear. The area of the structure obeys a power-law scaling with the number of spheres. Imaging shows that the regulation of motion of individual spheres occurs via toggling between two types of motion, namely, rolling and sliding. A low density of weakly frictional rollers congregates near the sharp leading edge whereas a denser rear comprises highly frictional sliders. Experiments further suggest that because the rolling and sliding friction coefficients differ substantially, the spheres acquire a local time-averaged coefficient of friction within a large range of intermediate values in the system. The various sets of spatial and temporal configurations of the rollers and sliders constitute the internal states of the system. Experiments demonstrate and simulations confirm that the global features of the structure are maintained robustly by autotuning of friction through these internal states, providing a previously unidentified route to self-organization of a many-body system.

Teledermatology: from historical perspective to emerging techniques of the modern era: part I: History, rationale, and current practice.

PubMed

Coates, Sarah J; Kvedar, Joseph; Granstein, Richard D

2015-04-01

Telemedicine is the use of telecommunications technology to support health care at a distance. Technological advances have progressively increased the ability of clinicians to care for diverse patient populations in need of skin expertise. Dermatology relies on visual cues that are easily captured by imaging technologies, making it ideally suited for this care model. Moreover, there is a shortage of medical dermatologists in the United States, where skin disorders account for 1 in 8 primary care visits and specialists tend to congregate in urban areas. Even in regions where dermatologic expertise is readily accessible, teledermatology may serve as an alternative that streamlines health care delivery by triaging chief complaints and reducing unnecessary in-person visits. In addition, many patients in the developing world have no access to dermatologic expertise, rendering it possible for teledermatologists to make a significant contribution to patient health outcomes. Teledermatology also affords educational benefits to primary care providers and dermatologists, and enables patients to play a more active role in the health care process by promoting direct communication with dermatologists. Copyright © 2014 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Meals for the Elderly

NASA Technical Reports Server (NTRS)

1977-01-01

NASA is drawing upon its food-preparation expertise to assist in solving a problem affecting a large segment of the American population. In preparation for manned space flight programs, NASA became experienced in providing astronauts simple, easily-prepared, nutritious meals. That experience now is being transferred to the public sector in a cooperative project managed by Johnson Space Center. Called Meal System for the Elderly, the project seeks to fill a gap by supplying nutritionally balanced meal packages to those who are unable to participate in existing meal programs. Many such programs are conducted by federal, state and private organizations, including congregate hot meal services and home-delivered "meals on wheels." But more than 3.5 million elderly Americans are unable to take advantage of these benefits. In some cases, they live in rural areas away from available services; in others, they are handicapped, temporarily ill, or homebound for other reasons. Meal System for the Elderly, a cooperative program in which the food-preparation expertise NASA acquired in manned space projects is being utilized to improve the nutritional status of elderly people. The program seeks to fill a gap by supplying nutritionally-balanced food packages to the elderly who are unable to participate b existing meal service programs.

Beyond 9-ODA: sex pheromone communication in the European honey bee Apis mellifera L.

PubMed

Brockmann, Axel; Dietz, Daniel; Spaethe, Johannes; Tautz, Jürgen

2006-03-01

The major component of the mandibular gland secretion of queen honeybees (Apis mellifera L.), 9-ODA ((2E)-9-oxodecenoic acid), has been known for more than 40 yr to function as a long-range sex pheromone, attracting drones at congregation areas and drone flyways. Tests of other mandibular gland components failed to demonstrate attraction. It remained unclear whether these components served any function in mating behavior. We performed dual-choice experiments, using a rotating drone carousel, to test the attractiveness of 9-ODA compared to mixtures of 9-ODA with three other most abundant components in virgin queen mandibular gland secretions: (2E)-9-hydroxydecenoic acid (9-HDA), (2E)-10-hydroxydecenoic acid (10-HDA), and p-hydroxybenzoate (HOB). We found no differences in the number of drones attracted to 9-ODA or the respective mixtures over a distance. However, adding 9-HDA and 10-HDA, or 9-HDA, 10-HDA, and HOB to 9-ODA increased the number of drones making contact with the baited dummy. On the basis of these results, we suggest that at least 9-HDA and 10-HDA are additional components of the sex pheromone blend of A. mellifera.

Community Priorities for Healthy Eating in Older Adults.

PubMed

Jiang, Qianzhi; Cohen, Nancy L; Marra, Melissa Ventura; Woolf, Kathleen; Gilbride, Judith; Francis, Sarah L

2017-01-01

Community planners such as policymakers and health care and nutrition service providers can create an "age-friendly" environment to support healthy eating in older residents by addressing the highest priorities that enable older adults to improve their dietary intake through different food-related community settings. To identify and prioritize these factors that facilitate behavioral change (enablers) and behavioral settings important for older adult nutrition based on the social ecological model, nutrition and aging professionals (n = 30) from two rural (West Virginia, Iowa) and two urban (Massachusetts, New York) city/county regions (communities) participated in an online or live focus group discussion and completed an analytic hierarchy process survey online. Overall, the most important perceived enablers were accessibility and cost, followed by transportation and social support, but their relative importance varied by community. Participants from all communities considered congregate meal sites and food banks among the most important behavioral settings. Participants from most communities considered food stores to be important and also highlighted other settings unique to the area, such as senior housing, neighborhood, and farmers' markets. By targeting interventions to address the most notable enablers and behavioral settings specific to their community, planning groups can enhance their older residents' ability to achieve optimal nutritional health.

Consensus statements from the Workshop "Probiotics and Health: Scientific evidence".

PubMed

Guarner, F; Requena, T; Marcos, A

2010-01-01

This report shows the level of scientific consensus on definition, characteristics and health benefits of probiotics. The content of the report has derived from the scientific meeting: Workshop on Probiotics and Health. Scientific evidence, that congregated several Spanish experts, including gastroenterologists, microbiologists, nutritionists, immunologists and food technologists, among others, who have agreed with the statements shown in this document. Each statement has been sustained with the most relevant scientific aspects that were discussed during the Workshop and the following evaluation of the report by all experts who approved and signed it.

Developing an adequate "pneumatraumatology": understanding the spiritual impacts of traumatic injury.

PubMed

Bidwell, Duane R

2002-01-01

Psychosocial interventions and systematic theology are primary resources for chaplains and congregational pastors who care for victims of physical trauma. Yet these resources may not be adequate to address the spiritual impacts of trauma. This article proposes a preliminary "pneumatraumatology," drawing on early Christian asceticism and Buddhist mysticism to describe one way of understanding the spiritual impacts of traumatic injury. It also suggests possible responses to these impacts informed by narrative/constructionist perspectives and Breggemann's understanding of the dimensions of spiritual transformation in the Hebrew Bible.

Rats and bunnies: core kids in an American mall.

PubMed

Lewis, G H

1989-01-01

Although adolescents use shopping malls as important places of congregation, very little attention has been paid to this phenomenon by social scientists. This paper reports on a qualitative, interview-based study of adolescents in a New England shopping mall. Regular, day-to-day frequenters (N = 23) were identified and interviewed extensively over a six-week period in 1988. These "core kids" exhibited a good deal of alienation from both family and school, and used the mall as a neutral ground on which to create a fragile but mutually supportive community of kind.

Evidence of Lake Trout reproduction at Lake Michigan's mid-lake reef complex

USGS Publications Warehouse

Janssen, J.; Jude, D.J.; Edsall, T.A.; Paddock, R.W.; Wattrus, N.; Toneys, M.; McKee, P.

2006-01-01

The Mid-Lake Reef Complex (MLRC), a large area of deep (> 40 m) reefs, was a major site where indigenous lake trout (Salvelinus namaycush) in Lake Michigan aggregated during spawning. As part of an effort to restore Lake Michigan's lake trout, which were extirpated in the 1950s, yearling lake trout have been released over the MLRC since the mid-1980s and fall gill net censuses began to show large numbers of lake trout in spawning condition beginning about 1999. We report the first evidence of viable egg deposition and successful lake trout fry production at these deep reefs. Because the area's existing bathymetry and habitat were too poorly known for a priori selection of sampling sites, we used hydroacoustics to locate concentrations of large fish in the fall; fish were congregating around slopes and ridges. Subsequent observations via unmanned submersible confirmed the large fish to be lake trout. Our technological objectives were driven by biological objectives of locating where lake trout spawn, where lake trout fry were produced, and what fishes ate lake trout eggs and fry. The unmanned submersibles were equipped with a suction sampler and electroshocker to sample eggs deposited on the reef, draw out and occasionally catch emergent fry, and collect egg predators (slimy sculpin Cottus cognatus). We observed slimy sculpin to eat unusually high numbers of lake trout eggs. Our qualitative approaches are a first step toward quantitative assessments of the importance of lake trout spawning on the MLRC.

Publication trend, resource utilization, and impact of the US National Cancer Database: A systematic review.

PubMed

Su, Chang; Peng, Cuiying; Agbodza, Ena; Bai, Harrison X; Huang, Yuqian; Karakousis, Giorgos; Zhang, Paul J; Zhang, Zishu

2018-03-01

The utilization and impact of the studies published using the National Cancer Database (NCDB) is currently unclear. In this study, we aim to characterize the published studies, and identify relatively unexplored areas for future investigations. A literature search was performed using PubMed in January 2017 to identify all papers published using NCDB data. Characteristics of the publications were extracted. Citation frequencies were obtained through the Web of Science. Three hundred 2 articles written by 230 first authors met the inclusion criteria. The number of publications grew exponentially since 2013, with 108 articles published in 2016. Articles were published in 86 journals. The majority of the published papers focused on digestive system cancer, while bone and joints, eye and orbit, myeloma, mesothelioma, and Kaposi Sarcoma were never studied. Thirteen institutions in the United States were associated with more than 5 publications. The papers have been cited for a total of 9858 times since the publication of the first paper in 1992. Frequently appearing keywords congregated into 3 clusters: "demographics," "treatments and survival," and "statistical analysis method." Even though the main focuses of the articles captured a extremely wide range, they can be classified into 2 main categories: survival analysis and characterization. Other focuses include database(s) analysis and/or comparison, and hospital reporting. The surging interest in the use of NCDB is accompanied by unequal utilization of resources by individuals and institutions. Certain areas were relatively understudied and should be further explored.

Facilitators and Barriers to Implementing Church-Based Adolescent Sexual Health Programs in Baltimore City.

PubMed

Powell, Terrinieka W; Weeks, Fiona H; Illangasekare, Samantha; Rice, Eric; Wilson, James; Hickman, Debra; Blum, Robert W

2017-02-01

Black churches are an important community resource and a potentially powerful actor in adolescent health promotion. However, limited research exists describing the factors that may influence the successful implementation of evidence-based adolescent sexual health programs in churches. In the present study, a multi-informant approach was used to identify facilitators and barriers to implementing adolescent sexual health programs in black churches. Nine Black churches located in Baltimore, MD, were recruited to participate in this study. The senior pastor and youth minster from each congregation participated in an in-depth interview (N = 18). A total of 45 youth (ages 13-19 years) and 38 parents participated in 15 focus groups. Qualitative data were transcribed verbatim and analyzed using a qualitative content analytic approach. Participants agreed that comprehensive adolescent sexual health education should be available for youth in black churches. They also believed that abstaining from sex should be discussed in all adolescent sexual health programs. Three facilitators were discussed: widespread endorsement of church-based adolescent sexual health education, positive influence of youth ministers on youth, and life lessons as teaching tools. Four barriers are described: perceived resistance from congregants, discomfort among youth, lack of financial resources, and competing messages at home about sexual health. Our findings suggest that churches are a preferred place for adolescent sexual health education among some parents and youth. Study findings also reinforce the feasibility and desirably of church-based adolescent sexual health programs. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

A Reactive Balance Rating Method that Correlates with Kinematics after Trip-Like Perturbations on a Treadmill and Fall Risk Among Residents of Older Adult Congregate Housing.

PubMed

Madigan, Michael L; Aviles, Jessica; Allin, Leigh J; Nussbaum, Maury A; Alexander, Neil B

2018-04-16

A growing number of studies are using modified treadmills to train reactive balance after trip-like perturbations that require multiple steps to recover balance. The goal of this study was thus to develop and validate a low-tech reactive balance rating method in the context of trip-like treadmill perturbations to facilitate the implementation of this training outside the research setting. Thirty-five residents of five senior congregate housing facilities participated in the study. Subjects completed a series of reactive balance tests on a modified treadmill from which the reactive balance rating was determined, along with a battery of standard clinical balance and mobility tests that predict fall risk. We investigated the strength of correlation between the reactive balance rating and reactive balance kinematics. We compared the strength of correlation between the reactive balance rating and clinical tests predictive of fall risk, with the strength of correlation between reactive balance kinematics and the same clinical tests. We also compared the reactive balance rating between subjects predicted to be at a high or low risk of falling. The reactive balance rating was correlated with reactive balance kinematics (Spearman's rho squared = .04 - .30), exhibited stronger correlations with clinical tests than most kinematic measures (Spearman's rho squared = .00 - .23), and was 42-60% lower among subjects predicted to be at a high risk for falling. The reactive balance rating method may provide a low-tech, valid measure of reactive balance kinematics, and an indicator of fall risk, after trip-like postural perturbations.

Food Insecurity and Eating Behavior Relationships Among Congregate Meal Participants in Georgia.

PubMed

Myles, TaMara; Porter Starr, Kathryn N; Johnson, Kristen B; Sun Lee, Jung; Fischer, Joan G; Ann Johnson, Mary

2016-01-01

This study explored relationships of food insecurity with cognitive restraint, uncontrolled eating, and emotional eating behaviors among congregate meal participants in northeast Georgia [n = 118 years, age 60 years and older, mean (SD) age = 75 ( 8 ) years, 75% female, 43% Black, 53% obese (Body Mass Index ≥ 30)]. Food insecurity was assessed with a 6-item questionnaire. Scores ranged from 0 to 6 and were defined as high or marginal food security, FS, 0-1 (70%); low food security, LFS, 2-4 (20%); very low food security, VLFS, 5-6 (10%); and low and very low food security, LVLFS, 2-6 (30%). Eating behavior was assessed with an 18-item Three-Factor Eating Questionnaire R-18. In bivariate analyses food insecurity was consistently associated with cognitive restraint scores above the median split and to a lesser extent with uncontrolled eating scores (p ≤ 0.05). No association was found between emotional eating and food insecurity. In multivariate linear and logistic regression analyses, food insecurity was consistently associated with cognitive restraint (p ≤ 0.05) even when controlled for potential confounders (demographics, Body Mass Index, and chronic diseases). Food insecurity was also associated with uncontrolled eating (p ≤ 0.05), but the relationship was attenuated when controlled for potential confounding variables. Although cognitive restraint is defined as the conscious restriction of food intake to control body weight or promote weight loss, these findings suggest there may be other dimensions of cognitive restraint to consider in nutritional assessment and interventions among food-insecure older adults.

Seeking and Accepting: U.S. Clergy Theological and Moral Perspectives Informing Decision Making at the End of Life.

PubMed

Sanders, Justin J; Chow, Vinca; Enzinger, Andrea C; Lam, Tai-Chung; Smith, Patrick T; Quiñones, Rebecca; Baccari, Andrew; Philbrick, Sarah; White-Hammond, Gloria; Peteet, John; Balboni, Tracy A; Balboni, Michael J

2017-10-01

People with serious illness frequently rely on religion/spirituality to cope with their diagnosis, with potentially positive and negative consequences. Clergy are uniquely positioned to help patients consider medical decisions at or near the end of life within a religious/spiritual framework. We aimed to examine clergy knowledge of end-of-life (EOL) care and beliefs about the role of faith in EOL decision making for patients with serious illness. Key informant interviews, focus groups, and survey. A purposive sample of 35 active clergy in five U.S. states as part of the National Clergy End-of-Life Project. We assessed participant knowledge of and desire for further education about EOL care. We transcribed interviews and focus groups for the purpose of qualitative analysis. Clergy had poor knowledge of EOL care; 75% desired more EOL training. Qualitative analysis revealed a theological framework for decision making in serious illness that balances seeking life and accepting death. Clergy viewed comfort-focused treatments as consistent with their faith traditions' views of a good death. They employed a moral framework to determine the appropriateness of EOL decisions, which weighs the impact of multiple factors and upholds the importance of God-given free will. They viewed EOL care choices to be the primary prerogative of patients and families. Clergy described ambivalence about and a passive approach to counseling congregants about decision making despite having defined beliefs regarding EOL care. Poor knowledge of EOL care may lead clergy to passively enable congregants with serious illness to pursue potentially nonbeneficial treatments that are associated with increased suffering.

Health promotion in local churches in Victoria: an exploratory study.

PubMed

Ayton, Darshini; Manderson, Lenore; Smith, Ben J; Carey, Gemma

2016-11-01

Church-based health promotion has increasingly gained attention in strategies to address health disparities. In Australia, we have limited understanding of the role of local churches in health promotion and without this, how they might be involved in meaningful partnerships to tackle public health challenges. The objective of this qualitative study was to explore how churches are involved in health promotion in the state of Victoria. The research involved in-depth interviews with ministers from 30 churches in urban and rural Victoria, and case studies with 10 of these churches to enable further exploration. These case studies, conducted in 2010, included interviews with church staff, focus groups with volunteers, participant observation and document analysis. Analysis was iterative, utilising open, axial and thematic coding. Three different expressions of church - traditional, new modern and emerging - were identified and found to differentiate the levels and types of health promotion activity. Case studies illustrate the different expressions of how church mission influences health promotion activity. The traditional churches were involved particularly in disease screening and health education activities with their own, predominantly older congregation members. The new modern churches tended to have the material and human resources to be harnessed in health promotion activities involving congregation members and others. Emerging churches, in contrast, engaged in broad health-promoting activities, including disease prevention, lifestyle activities and socio-ecological approaches at a community level. These research findings highlight the opportunities and challenges of engaging with local churches in health promotion efforts and public health programmes to address health inequities. © 2015 John Wiley & Sons Ltd.

Pokémon Go and Exposure to Mosquito-Borne Diseases: How Not to Catch ‘Em All

PubMed Central

Oidtman, Rachel J.; Christofferson, Rebecca C.; ten Bosch, Quirine A.; Espana, Guido; Kraemer, Moritz U. G.; Tatem, Andrew; Barker, Christopher M.; Perkins, T. Alex

2016-01-01

Pokémon Go is a new game that encourages players to venture outdoors and interact with others in the pursuit of virtual Pokémon characters. With more time spent outdoors overall and in sometimes large congregations, Pokémon Go players could inadvertently elevate their risk of exposure to mosquito-borne diseases when playing in certain areas at certain times of year. Here, we make an initial assessment of the possible scope of this concern in the continental United States, which experiences its highest seasonal transmission of West Nile, Zika, and other viruses during summer and early fall. In particular, we propose that the times of day when many disease-relevant mosquito species are most likely to engage in blood feeding coincide with times of day when Pokémon Go activity is likely to be high, and we note that locations serving as hubs of Pokémon Go activity may in some cases overlap with areas where these mosquitoes are actively engaged in blood feeding. Although the risk of mosquito-borne diseases in the continental U.S. is low overall and is unlikely to be impacted significantly by Pokémon Go, it is nonetheless important for Pokémon Go players and others who spend time outdoors engaging in activities such as barbecues and gardening to be aware of these ongoing risks and to take appropriate preventative measures in light of the potential for outdoor activity to modify individual-level risk of exposure. As Pokémon Go and other augmented reality games become available in other parts of the world, similar risks should be assessed in a manner that is consistent with the local epidemiology of mosquito-borne diseases in those areas. PMID:28042515

Pokémon Go and Exposure to Mosquito-Borne Diseases: How Not to Catch 'Em All.

PubMed

Oidtman, Rachel J; Christofferson, Rebecca C; Ten Bosch, Quirine A; Espana, Guido; Kraemer, Moritz U G; Tatem, Andrew; Barker, Christopher M; Perkins, T Alex

2016-11-15

Pokémon Go is a new game that encourages players to venture outdoors and interact with others in the pursuit of virtual Pokémon characters. With more time spent outdoors overall and in sometimes large congregations, Pokémon Go players could inadvertently elevate their risk of exposure to mosquito-borne diseases when playing in certain areas at certain times of year. Here, we make an initial assessment of the possible scope of this concern in the continental United States, which experiences its highest seasonal transmission of West Nile, Zika, and other viruses during summer and early fall. In particular, we propose that the times of day when many disease-relevant mosquito species are most likely to engage in blood feeding coincide with times of day when Pokémon Go activity is likely to be high, and we note that locations serving as hubs of Pokémon Go activity may in some cases overlap with areas where these mosquitoes are actively engaged in blood feeding. Although the risk of mosquito-borne diseases in the continental U.S. is low overall and is unlikely to be impacted significantly by Pokémon Go , it is nonetheless important for Pokémon Go players and others who spend time outdoors engaging in activities such as barbecues and gardening to be aware of these ongoing risks and to take appropriate preventative measures in light of the potential for outdoor activity to modify individual-level risk of exposure. As Pokémon Go and other augmented reality games become available in other parts of the world, similar risks should be assessed in a manner that is consistent with the local epidemiology of mosquito-borne diseases in those areas.

Discussing Adolescent Sexual Health in African American Churches

PubMed Central

Williams, Terrinieka T.; Dodd, Darcy; Campbell, Bettina; Pichon, Latrice C.; Griffith, Derek M.

2012-01-01

This study describes the ways in which two African American churches discuss adolescent sexual health topics. Six focus groups were conducted in two churches in Flint, Michigan that reported no formal sexual health programming for their congregants. Three themes emerged to highlight the different perspectives about the role of churches in adolescent sexual decision-making and sexual health education 1) churches as sources of sexual information; 2) churches as complex communities; and 3) recommendations for sexual education in churches. Participant responses suggest that churches can and should serve a resource for sexual health information. Implications for practice and research are discussed. PMID:22814618

Paramecium swimming in a capillary tube

NASA Astrophysics Data System (ADS)

Jana, Saikat; Jung, Sunghwan

2010-03-01

Micro-organisms exhibit different strategies for swimming in complex environments. Many micro-swimmers such as paramecium congregate and tend to live near wall. We investigate how paramecium moves in a confined space as compared to its motion in an unbounded fluid. A new theoretical model based on Taylor's sheet is developed, to study such boundary effects. In experiments, paramecia are put inside capillary tubes and their swimming behavior is observed. The data obtained from experiments is used to test the validity of our theoretical model and understand how the cilia influence the locomotion of paramecia in confined geometries.

The role of religious leaders in health promotion for older Mexicans with diabetes.

PubMed

Rivera-Hernandez, Maricruz

2015-02-01

Clergy in the Mexico play a major role in addressing the health care needs of their congregants. With qualitative semi-structured key-informant interviews, this study explored the views of ten male Mexican religious leaders (mostly Catholic) about their understanding of their role in diabetes health promotion. The major themes from the qualitative interviews emphasized the importance of open communication between church leaders and their parishioners, the role of the church in diabetes programs, and the unique position of religious institutions as a link between physical and spiritual aspects of health. Implications for diabetes interventions are discussed.

The role of repressor kinetics in relief of transcriptional interference between convergent promoters

PubMed Central

Hao, Nan; Palmer, Adam C.; Ahlgren-Berg, Alexandra; Shearwin, Keith E.; Dodd, Ian B.

2016-01-01

Transcriptional interference (TI), where transcription from a promoter is inhibited by the activity of other promoters in its vicinity on the same DNA, enables transcription factors to regulate a target promoter indirectly, inducing or relieving TI by controlling the interfering promoter. For convergent promoters, stochastic simulations indicate that relief of TI can be inhibited if the repressor at the interfering promoter has slow binding kinetics, making it either sensitive to frequent dislodgement by elongating RNA polymerases (RNAPs) from the target promoter, or able to be a strong roadblock to these RNAPs. In vivo measurements of relief of TI by CI or Cro repressors in the bacteriophage λ PR–PRE system show strong relief of TI and a lack of dislodgement and roadblocking effects, indicative of rapid CI and Cro binding kinetics. However, repression of the same λ promoter by a catalytically dead CRISPR Cas9 protein gave either compromised or no relief of TI depending on the orientation at which it binds DNA, consistent with dCas9 being a slow kinetics repressor. This analysis shows how the intrinsic properties of a repressor can be evolutionarily tuned to set the magnitude of relief of TI. PMID:27378773

SWITCH: a dynamic CRISPR tool for genome engineering and metabolic pathway control for cell factory construction in Saccharomyces cerevisiae.

PubMed

Vanegas, Katherina García; Lehka, Beata Joanna; Mortensen, Uffe Hasbro

2017-02-08

The yeast Saccharomyces cerevisiae is increasingly used as a cell factory. However, cell factory construction time is a major obstacle towards using yeast for bio-production. Hence, tools to speed up cell factory construction are desirable. In this study, we have developed a new Cas9/dCas9 based system, SWITCH, which allows Saccharomyces cerevisiae strains to iteratively alternate between a genetic engineering state and a pathway control state. Since Cas9 induced recombination events are crucial for SWITCH efficiency, we first developed a technique TAPE, which we have successfully used to address protospacer efficiency. As proof of concept of the use of SWITCH in cell factory construction, we have exploited the genetic engineering state of a SWITCH strain to insert the five genes necessary for naringenin production. Next, the naringenin cell factory was switched to the pathway control state where production was optimized by downregulating an essential gene TSC13, hence, reducing formation of a byproduct. We have successfully integrated two CRISPR tools, one for genetic engineering and one for pathway control, into one system and successfully used it for cell factory construction.

Sequence determinants of improved CRISPR sgRNA design.

PubMed

Xu, Han; Xiao, Tengfei; Chen, Chen-Hao; Li, Wei; Meyer, Clifford A; Wu, Qiu; Wu, Di; Cong, Le; Zhang, Feng; Liu, Jun S; Brown, Myles; Liu, X Shirley

2015-08-01

The CRISPR/Cas9 system has revolutionized mammalian somatic cell genetics. Genome-wide functional screens using CRISPR/Cas9-mediated knockout or dCas9 fusion-mediated inhibition/activation (CRISPRi/a) are powerful techniques for discovering phenotype-associated gene function. We systematically assessed the DNA sequence features that contribute to single guide RNA (sgRNA) efficiency in CRISPR-based screens. Leveraging the information from multiple designs, we derived a new sequence model for predicting sgRNA efficiency in CRISPR/Cas9 knockout experiments. Our model confirmed known features and suggested new features including a preference for cytosine at the cleavage site. The model was experimentally validated for sgRNA-mediated mutation rate and protein knockout efficiency. Tested on independent data sets, the model achieved significant results in both positive and negative selection conditions and outperformed existing models. We also found that the sequence preference for CRISPRi/a is substantially different from that for CRISPR/Cas9 knockout and propose a new model for predicting sgRNA efficiency in CRISPRi/a experiments. These results facilitate the genome-wide design of improved sgRNA for both knockout and CRISPRi/a studies. © 2015 Xu et al.; Published by Cold Spring Harbor Laboratory Press.

Easy regulation of metabolic flux in Escherichia coli using an endogenous type I-E CRISPR-Cas system.

PubMed

Chang, Yizhao; Su, Tianyuan; Qi, Qingsheng; Liang, Quanfeng

2016-11-15

Clustered regularly interspaced short palindromic repeats interference (CRISPRi) is a recently developed powerful tool for gene regulation. In Escherichia coli, the type I CRISPR system expressed endogenously shall be easy for internal regulation without causing metabolic burden in compared with the widely used type II system, which expressed dCas9 as an additional plasmid. By knocking out cas3 and activating the expression of CRISPR-associated complex for antiviral defense (Cascade), we constructed a native CRISPRi system in E. coli. Downregulation of the target gene from 6 to 82% was demonstrated using green fluorescent protein. Regulation of the citrate synthase gene (gltA) in the TCA cycle affected host metabolism. The effect of metabolic flux regulation was demonstrated by the poly-3-hydroxbutyrate (PHB) accumulation in vivo. By regulating native gltA in E. coli using an engineered endogenous type I-E CRISPR system, we redirected metabolic flux from the central metabolic pathway to the PHB synthesis pathway. This study demonstrated that the endogenous type I-E CRISPR-Cas system is an easy and effective method for regulating internal metabolic pathways, which is useful for product synthesis.

Geographic variation in Bar-headed geese Anser indicus: connectivity of wintering and breeding grounds across a broad front

USGS Publications Warehouse

Takekawa, John Y.; Heath, Shane R.; Douglas, David C.; Perry, William M.; Javed, Sàlim; Newman, Scott H.; Suwal, Rajendra N.; Rahman, Asad R.; Choudhury, Binod C.; Prosser, Diann J.; Yan, Baoping; Hou, Yuansheng; Batbayar, Nyambayar; Natsagdorj, Tseveenmayadag; Bishop, Charles M.; Butler, Patrick J.; Frappell, Peter B.; Milsom, William K.; Scott, Graham R.; Hawkes, Lucy A.; Wikelski, Martin

2009-01-01

The connectivity and frequency of exchange between sub-populations of migratory birds is integral to understanding population dynamics over the entire species' range. True geese are highly philopatric and acquire lifetime mates during the winter, suggesting that the number of distinct sub-populations may be related to the number of distinct wintering areas. In the Bar-headed Goose Anser indicus, a species found exclusively in Central Asia, the connectivity between breeding and wintering areas is not well known. Their migration includes crossing a broad front of the Himalaya Cordillera, a significant barrier to migration for most birds. Many Bar-headed Geese fly to breeding areas on the Tibetan-Qinghai Plateau (TQP), the highest plateau in the world. From 2005-2008, 60 Bar-headed Geese were captured and marked with satellite transmitters in Nepal (n = 2), India (n = 6), China (n = 29), and Mongolia (n = 23) to examine their migration and distribution. Distinct differences were observed in their migration corridors and timing of movements, including an apparent leap-frog migration pattern for geese from Mongolia. Measurements of geese from Mongolia were larger than their counterparts from China, providing some evidence of morphological differences. Alteration of habitats in China, including the warming effects of climate change on glaciers increasing runoff to TQP wetlands, may be changing goose migration patterns and timing. With the exception of one individual, all geese from Qinghai Lake, China wintered in the southern TQP near Lhasa, and their increasing numbers in that region may be related to the effects of climate change and agricultural development. Thus, our findings document both morphological and geographical variation in sub-populations of Bar-headed Geese, but their resilience to environmental change may be lost if migratory short-stopping results in larger congregations restricted to a smaller number of wintering areas.

Risk factors for arbovirus infections in a low-income community of Rio de Janeiro, Brazil, 2015-2016

PubMed Central

Daumas, Regina Paiva; de Almeida, Andrea Sobral; dos Santos, Reinaldo Souza; Koster, Isabella; Rodrigues, Pedro Pinheiro; Gomes, Marcelly de Freitas; Macedo, Auriane de Fátima; Gerardi, Alyssa; Leite, Iúri da Costa

2018-01-01

Background Dengue epidemics have occurred in the city of Rio de Janeiro (Brazil) since 1986. In the year 2015, Zika and chikungunya viruses were introduced in the city, causing sequential and simultaneous epidemics. Poor socioeconomic conditions have been suggested as contributing factors of arboviral infection. Objective To describe the spatial distribution of human cases of symptomatic arboviral infections and to identify risk factors for infection in a poor community of Rio de Janeiro in the years 2015 and 2016. Methods We built thematic maps of incidence rates for 78 micro-areas in the Manguinhos neighborhood. The micro-areas congregate about 600 inhabitants. Simple and multiple multilevel logistic regression models were used to evaluate the association between the incidence of arboviral diseases and socio-demographic factors at both the individual and micro-area levels. Results From 2015 to 2016, 370 human cases of arbovirus infection were reported in the Manguinhos community: 123 in 2015 and 247 in 2016. There was a significant difference in the risk of arbovirus diseases among different micro-areas, but this was not explained by water and sanitation indicators. The cumulative incidence rate was 849/100,000 in two years. The incidence was greater in those individuals with familiar vulnerability (1,156/100,000 vs. 794/100,000). The multilevel adjusted model showed that the odds of acquiring an arbovirus infection was 55% greater in those with familiar vulnerability. Conclusion Arbovirus infections cause a high burden of disease in Brazilian urban centers. Our results suggest that even in poor neighborhoods, there is a high spatial variability in the risk of acquiring an arbovirus infection. The conditions that favor vector proliferation and infection by arboviruses are complex and involve both individual and environmental characteristics that vary from place to place. To reduce the burden of arboviral diseases, continued public health policies and basic services should be provided to the communities at risk that consider specific local needs. PMID:29879155

Integrating vegetation index time series and meteorological data to understand the effect of the land use/land cover (LULC) in the climatic seasonality of the Brazilian Cerrado

NASA Astrophysics Data System (ADS)

Lins, D. B.; Zullo, J.; Friedel, M. J.

2013-12-01

The Cerrado (savanna ecosystem) of São Paulo state (Brazil) represent a complex mosaic of different typologies of uses, actors and biophysical and social restrictions. Originally, 14% of the state of São Paulo area was covered by the diversity of Cerrado phytophysiognomies. Currently, only 1% of this original composition remains fragmented into numerous relicts of biodiversity, mainly concentrated in the central-eastern of the state. A relevant part of the fragments are found in areas of intense coverage change by human activities, whereas the greatest pressure comes from sugar cane cultivation, either by direct replacement of Cerrado vegetation or occupying pasture areas in the fragments edges. As a result, new local level dynamics has been introduced, directly or indirectly, affecting the established of processes in climate systems. In this study, the main goal is analyzing the relationship between the Cerrado landscape changing and the climate dynamics in regional and local areas. The multi-temporal MODIS 250 m Vegetation Index (VI) datasets (period of 2000 to 2012) are integrated with precipitation data of the correspondent period (http://www.agritempo.gov.br/),one of the most important variable of the spatial phytophysiognomies distribution. The integration of meteorological data enable the development of an integrated approach to understand the relationship between climatic seasonality and the changes in the spatial patterns. A procedure to congregated diverse dynamics information is the Self Organizing Map (SOM, Kohonen, 2001), a technique that relies on unsupervised competitive learning (Kohonen and Somervuo 2002) to recognize patterns. In this approach, high-dimensional data are represented on two dimensions, making possible to obtain patterns that takes into account information from different natures. Observed advances will contribute to bring machine-learning techniques as a valid tool to provide improve in land use/land cover (LULC) analyzes at different hierarchical scales to support numerous science and policy applications.

Implementing health promotion activities using community-engaged approaches in Asian American faith-based organizations in New York City and New Jersey.

PubMed

Kwon, S C; Patel, S; Choy, C; Zanowiak, J; Rideout, C; Yi, S; Wyatt, L; Taher, M D; Garcia-Dia, M J; Kim, S S; Denholm, T K; Kavathe, R; Islam, N S

2017-09-01

Faith-based organizations (FBOs) (e.g., churches, mosques, and gurdwaras) can play a vital role in health promotion. The Racial and Ethnic Approaches to Community Health for Asian Americans (REACH FAR) Project is implementing a multi-level and evidence-based health promotion and hypertension (HTN) control program in faith-based organizations serving Asian American (AA) communities (Bangladeshi, Filipino, Korean, Asian Indian) across multiple denominations (Christian, Muslim, and Sikh) in New York/New Jersey (NY/NJ). This paper presents baseline results and describes the cultural adaptation and implementation process of the REACH FAR program across diverse FBOs and religious denominations serving AA subgroups. Working with 12 FBOs, informed by implementation research and guided by a cultural adaptation framework and community-engaged approaches, REACH FAR strategies included (1) implementing healthy food policies for communal meals and (2) delivering a culturally-linguistically adapted HTN management coaching program. Using the Ecological Validity Model (EVM), the program was culturally adapted across congregation and faith settings. Baseline measures include (i) Congregant surveys assessing social norms and diet (n = 946), (ii) HTN participant program surveys (n = 725), (iii) FBO environmental strategy checklists (n = 13), and (iv) community partner in-depth interviews assessing project feasibility (n = 5). We describe the adaptation process and baseline assessments of FBOs. In year 1, we reached 3790 (nutritional strategies) and 725 (HTN program) via AA FBO sites. Most AA FBOs lack nutrition policies and present prime opportunities for evidence-based multi-level interventions. REACH FAR presents a promising health promotion implementation program that may result in significant community reach.

Social network types among older Korean adults: Associations with subjective health.

PubMed

Sohn, Sung Yun; Joo, Won-Tak; Kim, Woo Jung; Kim, Se Joo; Youm, Yoosik; Kim, Hyeon Chang; Park, Yeong-Ran; Lee, Eun

2017-01-01

With population aging now a global phenomenon, the health of older adults is becoming an increasingly important issue. Because the Korean population is aging at an unprecedented rate, preparing for public health problems associated with old age is particularly salient in this country. As the physical and mental health of older adults is related to their social relationships, investigating the social networks of older adults and their relationship to health status is important for establishing public health policies. The aims of this study were to identify social network types among older adults in South Korea and to examine the relationship of these social network types with self-rated health and depression. Data from the Korean Social Life, Health, and Aging Project were analyzed. Model-based clustering using finite normal mixture modeling was conducted to identify the social network types based on ten criterion variables of social relationships and activities: marital status, number of children, number of close relatives, number of friends, frequency of attendance at religious services, attendance at organized group meetings, in-degree centrality, out-degree centrality, closeness centrality, and betweenness centrality. Multivariate regression analysis was conducted to examine associations between the identified social network types and self-rated health and depression. The model-based clustering analysis revealed that social networks clustered into five types: diverse, family, congregant, congregant-restricted, and restricted. Diverse or family social network types were significantly associated with more favorable subjective mental health, whereas the restricted network type was significantly associated with poorer ratings of mental and physical health. In addition, our analysis identified unique social network types related to religious activities. In summary, we developed a comprehensive social network typology for older Korean adults. Copyright © 2016 Elsevier Ltd. All rights reserved.

Simple CPR: A randomized, controlled trial of video self-instructional cardiopulmonary resuscitation training in an African American church congregation.

PubMed

Todd, K H; Heron, S L; Thompson, M; Dennis, R; O'Connor, J; Kellermann, A L

1999-12-01

Despite the proven efficacy of cardiopulmonary resuscitation (CPR), only a small fraction of the population knows how to perform it. As a result, rates of bystander CPR and rates of survival from cardiac arrest are low. Bystander CPR is particularly uncommon in the African American community. Successful development of a simplified approach to CPR training could boost rates of bystander CPR and save lives. We conducted the following randomized, controlled study to determine whether video self-instruction (VSI) in CPR results in comparable or better performance than traditional CPR training. This randomized, controlled trial was conducted among congregational volunteers in an African American church in Atlanta, GA. Subjects were randomly assigned to receive either 34 minutes of VSI or the 4-hour American Heart Association "Heartsaver" CPR course. Two months after training, blinded observers used explicit criteria to assess CPR performance in a simulated cardiac arrest setting. A recording manikin was used to measure ventilation and chest compression characteristics. Participants also completed a written test of CPR-related knowledge and attitudes. VSI trainees displayed a comparable level of performance to that achieved by traditional trainees. Observers scored 40% of VSI trainees competent or better in performing CPR, compared with only 16% of traditional trainees (absolute difference 24%, 95% confidence interval 8% to 40%). Data from the recording manikin confirmed these observations. VSI trainees and traditional trainees achieved comparable scores on tests of CPR-related knowledge and attitudes. Thirty-four minutes of VSI can produce CPR of comparable quality to that achieved by traditional training methods. VSI provides a simple, quick, consistent, and inexpensive alternative to traditional CPR instruction, and may be used to extend CPR training to historically underserved populations.

Factors Associated with Seasonal Influenza Immunization among Church-going Older African Americans

PubMed Central

BOGGAVARAPU, Sahithi; SULLIVAN, Kevin M.; SCHAMEL, Jay T.; FREW, Paula M.

2014-01-01

Objectives Churches and faith institutions can frequently influence health behaviors among older African Americans. The church is a centerpiece of spiritual and social life among African American congregants. We explored its influence on influenza immunization coverage during the 2012–2013 influenza season. Methods A cross-sectional study was conducted among congregation members ages 50–89 years from six churches in the Atlanta region in 2013–2014. We computed descriptive statistics, bivariate associations, and multivariable models to examine factors associated with immunization uptake among this population. Results Of 208 study participants, 95 (45.7%) reported receiving the influenza vaccine. Logistic regression showed that increased trust in their healthcare providers’ vaccine recommendations was a positive predictor of vaccination among participants who had not experienced discrimination in a faith-based setting (OR: 14.8 [3.7,59.8]), but was not associated with vaccination for participants who had experienced such discrimination (OR: 1.5 [0.2,7.0]). Belief in vaccine-induced influenza illness (OR: 0.1 [0.05, 0.23]) was a negative predictor of influenza vaccination. Conclusion Members of this older cohort of African Americans who expressed trust in their healthcare providers’ vaccine recommendations and disbelief in vaccine-induced influenza were more likely to obtain seasonal influenza immunization. They were also more likely to act on their trust of healthcare provider’s vaccine recommendations if they did not encounter negative influenza immunization attitudes within the church. Having healthcare providers address negative influenza immunization attitudes and disseminate vaccine information in a culturally appropriate manner within the church has the potential to enhance future uptake of influenza vaccination. PMID:25444831

Holistic Health Care for the Medically Uninsured: The Church Health Center of Memphis.

PubMed

Morris, G Scott

2015-11-05

The Church Health Center (CHC) in Memphis was founded in 1987 to provide quality, affordable health care for working, uninsured people and their families. With numerous, dedicated financial supporters and health care volunteers, CHC has become the largest faith-based health care organization of its type nationally, serving >61,000 patients. CHC embraces a holistic approach to health by promoting wellness in every dimension of life. It offers on-site services including medical care, dentistry, optometry, counseling, social work, and nutrition and fitness education, to promote wellness in every dimension of life. A 2012 economic analysis estimated that a $1 contribution to the CHC provided roughly $8 in health services. The CHC has trained >1200 Congregational Health Promoters to be health leaders and is conducting research on the effectiveness of faith community nurses partnering with congregations to assist in home care for patients recently discharged from Memphis hospitals. The MEMPHIS Plan, CHC's employer-sponsored health care plan for small business and the self-employed, offers uninsured people in lower-wage jobs access to quality, affordable health care. The CHC also conducts replications workshops several times a year to share their model with leaders in other communities. The Institute for Healthcare Improvement (IHI) recently completed a case study that concluded: "The CHC is one of a very few organizations successfully embodying all three components of the IHI Triple Aim by improving population health outcomes, enhancing the individual's health care experience, and controlling costs. All three have been part of the Center's DNA since its inception, and as a transforming force in the community, the model is well worth national attention."

Housing First improves subjective quality of life among homeless adults with mental illness: 12-month findings from a randomized controlled trial in Vancouver, British Columbia.

PubMed

Patterson, Michelle; Moniruzzaman, Akm; Palepu, Anita; Zabkiewicz, Denise; Frankish, Charles J; Krausz, Michael; Somers, Julian M

2013-08-01

This study used an experimental design to examine longitudinal changes in subjective quality of life (QoL) among homeless adults with mental illness after assignment to different types of supported housing or to treatment as usual (TAU, no housing or supports through the study). We hypothesized that subjective QoL would improve over time among participants assigned to supported housing as compared to TAU, regardless of the type of supported housing received or participants' level of need. Participants (n = 497) were stratified by level of need ("high" or "moderate") and randomly assigned to Housing First (HF) in scattered-site apartments, HF in a congregate setting (high needs only), or TAU. Linear mixed-effects regression was used to model the association between study arm and self-reported QoL at baseline and at 6 and 12 months post-baseline by need level. Based on the adjusted overall score on the QoL measure, participants randomized to HF reported significantly greater overall QoL as compared to TAU, regardless of need level or type of supported housing at both 6 and 12 months post-baseline. Scores on the safety and living situation subscales were significantly greater for both high and moderate need participants assigned to supported housing regardless of type at both 6 and 12 months post-baseline as compared to TAU. Despite multiple health and social challenges faced by homeless individuals with mental illness, HF in both scattered-site and congregate models results in significantly greater perceived QoL as compared to individuals who do not receive HF even after a relatively short period of time.

Investigating Avian Influenza Infection Hotspots in Old-World Shorebirds

PubMed Central

Gaidet, Nicolas; Ould El Mamy, Ahmed B.; Cappelle, Julien; Caron, Alexandre; Cumming, Graeme S.; Grosbois, Vladimir; Gil, Patricia; Hammoumi, Saliha; de Almeida, Renata Servan; Fereidouni, Sasan R.; Cattoli, Giovanni; Abolnik, Celia; Mundava, Josphine; Fofana, Bouba; Ndlovu, Mduduzi; Diawara, Yelli; Hurtado, Renata; Newman, Scott H.; Dodman, Tim; Balança, Gilles

2012-01-01

Heterogeneity in the transmission rates of pathogens across hosts or environments may produce disease hotspots, which are defined as specific sites, times or species associations in which the infection rate is consistently elevated. Hotspots for avian influenza virus (AIV) in wild birds are largely unstudied and poorly understood. A striking feature is the existence of a unique but consistent AIV hotspot in shorebirds (Charadriiformes) associated with a single species at a specific location and time (ruddy turnstone Arenaria interpres at Delaware Bay, USA, in May). This unique case, though a valuable reference, limits our capacity to explore and understand the general properties of AIV hotspots in shorebirds. Unfortunately, relatively few shorebirds have been sampled outside Delaware Bay and they belong to only a few shorebird families; there also has been a lack of consistent oropharyngeal sampling as a complement to cloacal sampling. In this study we looked for AIV hotspots associated with other shorebird species and/or with some of the larger congregation sites of shorebirds in the old world. We assembled and analysed a regionally extensive dataset of AIV prevalence from 69 shorebird species sampled in 25 countries across Africa and Western Eurasia. Despite this diverse and extensive coverage we did not detect any new shorebird AIV hotspots. Neither large shorebird congregation sites nor the ruddy turnstone were consistently associated with AIV hotspots. We did, however, find a low but widespread circulation of AIV in shorebirds that contrast with the absence of AIV previously reported in shorebirds in Europe. A very high AIV antibody prevalence coupled to a low infection rate was found in both first-year and adult birds of two migratory sandpiper species, suggesting the potential existence of an AIV hotspot along their migratory flyway that is yet to be discovered. PMID:23029383

The Impact of Faith Beliefs on Perceptions of End-of-Life Care and Decision Making among African American Church Members.

PubMed

Johnson, Jerry; Hayden, Tara; True, Jennifer; Simkin, Daren; Colbert, Louis; Thompson, Beverly; Stewart, Denise; Martin, Latoya

2016-02-01

African Americans underuse palliative care and hospice services because of a combination of factors including faith beliefs. As the spiritual family for many African Americans, the church presents an opportunity to improve communication about palliative care and hospice and end-of-life (EOL) decision making. We conducted a focus group study to understand the cultural and spiritual perspectives that influence decisions about palliative care and hospice among African American church members who visit and support persons with life-limiting illnesses. Our specific aims were to elicit their perceptions, beliefs, and attitudes about: (1) the relation between faith beliefs and EOL care; (2) emotional and family influences on EOL decision making; (3) palliative care and hospice resources; and (4) opportunities to improve communication among lay persons and health professionals and within families. Seven focus groups using purposeful sampling. We partnered with two African American churches. Of 51 persons, 27 were deacons or deaconesses, 17 were members of health or bereavement ministries, and 7 were other members of the congregations. We found that faith beliefs of African Americans can support discussions about palliative care and hospice. Participants perceived that many of their congregants harbor beliefs, perceptions, and feelings about death and dying that were often not communicated to family members or to health providers. Among African Americans, faith beliefs, emotional issues, family dynamics, and insufficient knowledge of palliative care and hospice are intertwined and influence decision making about palliative care and hospice. Our findings confirm the influence of faith beliefs of African Americans on decisions about palliative care and hospice and demonstrate the opportunity to improve communication about palliative care and hospice and EOL through collaborations with the African American church.

Involvement of an Actomyosin Contractile Ring in Saccharomyces cerevisiae Cytokinesis

PubMed Central

Bi, Erfei; Maddox, Paul; Lew, Daniel J.; Salmon, E.D.; McMillan, John N.; Yeh, Elaine; Pringle, John R.

1998-01-01

In Saccharomyces cerevisiae, the mother cell and bud are connected by a narrow neck. The mechanism by which this neck is closed during cytokinesis has been unclear. Here we report on the role of a contractile actomyosin ring in this process. Myo1p (the only type II myosin in S. cerevisiae) forms a ring at the presumptive bud site shortly before bud emergence. Myo1p ring formation depends on the septins but not on F-actin, and preexisting Myo1p rings are stable when F-actin is depolymerized. The Myo1p ring remains in the mother–bud neck until the end of anaphase, when a ring of F-actin forms in association with it. The actomyosin ring then contracts to a point and disappears. In the absence of F-actin, the Myo1p ring does not contract. After ring contraction, cortical actin patches congregate at the mother–bud neck, and septum formation and cell separation rapidly ensue. Strains deleted for MYO1 are viable; they fail to form the actin ring but show apparently normal congregation of actin patches at the neck. Some myo1Δ strains divide nearly as efficiently as wild type; other myo1Δ strains divide less efficiently, but it is unclear whether the primary defect is in cytokinesis, septum formation, or cell separation. Even cells lacking F-actin can divide, although in this case division is considerably delayed. Thus, the contractile actomyosin ring is not essential for cytokinesis in S. cerevisiae. In its absence, cytokinesis can still be completed by a process (possibly localized cell–wall synthesis leading to septum formation) that appears to require septin function and to be facilitated by F-actin. PMID:9732290

Reliability and validity of the brief multidimensional measure of religiousness/spirituality among adolescents.

PubMed

Harris, Sion Kim; Sherritt, Lon R; Holder, David W; Kulig, John; Shrier, Lydia A; Knight, John R

2008-12-01

Developed for use in health research, the Brief Multidimensional Measure of Religiousness/Spirituality (BMMRS) consists of brief measures of a broad range of religiousness and spirituality (R/S) dimensions. It has established psychometric properties among adults, but little is known about its appropriateness for use with adolescents. We assessed the psychometric properties of the BMMRS among adolescents. We recruited a racially diverse (85% non-White) sample of 305 adolescents aged 12-18 years (median 16 yrs, IQR 14-17) from 3 urban medical clinics; 93 completed a retest 1 week later. We assessed internal consistency and test-retest reliability. We assessed construct validity by examining how well the measures discriminated groups expected to differ based on self-reported religious preference, and how they related to a hypothesized correlate, depressive symptoms. Religious preference was categorized into "No religion/Atheist" (11%), "Don't know/Confused" (9%), or "Named a religion" (80%). Responses to multi-item measures were generally internally consistent (alpha > or = 0.70 for 12/16 measures) and stable over 1 week (intraclass correlation coefficients > or = 0.70 for 14/16). Forgiveness, Negative R/S Coping, and Commitment items showed lower internal cohesiveness. Scores on most measures were higher (p < 0.05) among those who "Named a religion" compared to the "No religion/Atheist" group. Forgiveness, Commitment, and Anticipated Support from members of one's congregation were inversely correlated with depressive symptoms, while BMMRS measures assessing negative R/S experiences (Negative R/S Coping, Negative Interactions with others in congregation, Loss in Faith) were positively correlated with depressive symptoms. These findings suggest that most BMMRS measures are reliable and valid for use among adolescents.

Examining differences in types and location of recruitment venues for young males and females from urban neighborhoods: findings from a multi-site HIV prevention study.

PubMed

Chutuape, Kate S; Ziff, Mauri; Auerswald, Colette; Castillo, Marné; McFadden, Antionette; Ellen, Jonathan

2009-01-01

Finding and accessing members of youth subpopulations, such as young men who have sex with men (YMSM) of color or young females of color, for behavioral or disease surveillance or study recruitment, pose particular challenges. Venue-based sampling strategies--which hinge on where individuals congregate or "hang out" rather than where they live--appear to be effective alternatives. Methods used to identify venues focus on engaging members of social networks to learn where targeted populations congregate. However, it is not always clear if and how these methods differ according to gender, whether the youth accessed at a venue are actually from neighborhoods in which the venues are found, and whether the location of venues relative to neighborhoods of residence is different for young men and young women. This study illustrates the gender differences in venue type and venue location where eligible youth study participants from high-risk neighborhoods could be accessed for HIV research across 15 research sites (sites). The findings indicate that the study's method led to identifying venues where one quarter or more of the youth were eligible study participants and from the high-risk neighborhoods. Sites targeting young women of color had a higher proportion of eligible study participants who were also from the high-risk neighborhoods than sites targeting YMSM. Clubs were most commonly identified by sites targeting YMSM as recruitment venues, whereas neighborhood-based service or commercial centers were more common venues for young women of color. This study reveals how venue-based recruitment strategies can be tailored and resources maximized by understanding the key differences in the types of venues preferred by males and females and by recognizing that female-preferred venues are more likely to be closer to home.

Neural basis of imprinting behavior in chicks.

PubMed

Nakamori, Tomoharu; Maekawa, Fumihiko; Sato, Katsushige; Tanaka, Kohichi; Ohki-Hamazaki, Hiroko

2013-01-01

Newly hatched chicks memorize the characteristics of the first moving object they encounter, and subsequently show a preference for it. This "imprinting" behavior is an example of infant learning and is elicited by visual and/or auditory cues. Visual information of imprinting stimuli in chicks is first processed in the visual Wulst (VW), a telencephalic area corresponding to the mammalian visual cortex, congregates in the core region of the hyperpallium densocellulare (HDCo) cells, and transmitted to the intermediate medial mesopallium (IMM), a region similar to the mammalian association cortex. The imprinting memory is stored in the IMM, and activities of IMM neurons are altered by imprinting. Imprinting also induces functional and structural plastic changes of neurons in the circuit that links the VW and the IMM. Of these neurons, the activity of the HDCo cells is strongly influenced by imprinting. Expression and modulation of NR2B subunit-containing N-methyl-D-aspartate (NMDA) receptors in the HDCo cells are crucial for plastic changes in this circuit as well as the process of visual imprinting. Thus, elucidation of cellular and molecular mechanisms underlying the plastic changes that occurred in the HDCo cells may provide useful knowledge about infant learning. © 2012 The Authors Development, Growth & Differentiation © 2012 Japanese Society of Developmental Biologists.

The science of early adversity: is there a role for large institutions in the care of vulnerable children?

PubMed

Berens, Anne E; Nelson, Charles A

2015-07-25

It has been more than 80 years since researchers in child psychiatry first documented developmental delays among children separated from family environments and placed in orphanages or other institutions. Informed by such findings, global conventions, including the 1989 UN Convention on the Rights of the Child, assert a child's right to care within a family-like environment that offers individualised support. Nevertheless, an estimated 8 million children are presently growing up in congregate care institutions. Common reasons for institutionalisation include orphaning, abandonment due to poverty, abuse in families of origin, disability, and mental illness. Although the practice remains widespread, a robust body of scientific work suggests that institutionalisation in early childhood can incur developmental damage across diverse domains. Specific deficits have been documented in areas including physical growth, cognitive function, neurodevelopment, and social-psychological health. Effects seem most pronounced when children have least access to individualised caregiving, and when deprivation coincides with early developmental sensitive periods. Offering hope, early interventions that place institutionalised children into families have afforded substantial recovery. The strength of scientific evidence imparts urgency to efforts to achieve deinstitutionalisation in global child protection sectors, and to intervene early for individual children experiencing deprivation. Copyright © 2015 Elsevier Ltd. All rights reserved.

KSC-2014-2072

NASA Image and Video Library

2014-04-13

CAPE CANAVERAL, Fla. - Members of the winning Astronaut Resource Managing System and SpaceWear teams in the International Space Apps Challenge pose for a group portrait with the NASA volunteers, judges and event organizers. From left are Alejandro Velasco, NASA's Justin Treptow, Sam Neblett, Roberto Ricci, James Brucato, NASA's Suzanne Plantec, Keith Hargett, NASA's Cynthia Duffaut, NASA's Launa Maier, event organizer James Wood, event organizer lead Caley Burke, NASA's Lisa Singleton, event organizer David Miranda, NASA Ground Systems Development and Operation Program Manager Michael Bolger and NASA intern Brandi Burse. Kennedy Space Center hosted one of the over 90 locations around the world where participants congregated for the attempt to design innovative solutions for global challenges over a 48-hour period. This year's development marathon focused on five NASA mission areas: Asteroids, Earth Watch, Human Spaceflight, Robotics, and Technology in Space. Three of this year’s challenges were developed by KSC employees: Space Wearables: Fashion Designer to Astronauts, Growing Food for a Martian Table, and Asteroid Prospector. The winners selected in 2014 at Kennedy were Astronaut Resource Managing System, or ARMS, for Best Use of Data and SpaceWear for Best Use of Hardware. ARMS also took the People's Choice Award. For more information, visit https://2014.spaceappschallenge.org. Photo credit: NASA/Daniel Casper

Cold-water refuges for climate resilience in Oregon coastal ...

EPA Pesticide Factsheets

Many rivers and streams in the Pacific Northwest are currently listed as impaired under the Clean Water Act as a result of high summer water temperatures. Adverse effects of warm waters include impacts to salmon and steelhead populations that may already be stressed by habitat alteration, disease, predation, and fishing pressures. Thermal refuges may help mitigate the effects of increasing temperatures. In this presentation, we define cold-water refuges as areas buffered from regional climate effects by groundwater, physical habitat heterogeneity, or other watershed attributes. Processes forming these features include groundwater-surface water interactions, and hyporheic exchange at a range of spatial and temporal scales. Patterns associated with these processes may provide useful indicators for mapping and predicting the locations and extent of these features. Fish may congregate at high densities within cold-water refuges during critical periods of thermal stress, but there may be trade-offs associated with refuge use including predation, disease risk, and reduced foraging opportunities. These factors all contribute to determining refuge effectiveness. Watershed management and restoration strategies could consider these features and their potential utility to cold-water fish, and we conclude with examples of types of watershed restoration actions that might help foster cold-water refuge creation and maintenance.M Many rivers and streams in the Pacific Nort

[Mental health of homeless persons. Critical review of the Anglo-Saxon literature].

PubMed

Ducq, H; Guesdon, I; Roelandt, J L

1997-01-01

Because the visibility of homeless persons congregating in urban areas has increased since the 1980's, the relationship between homelessness and mental illness has caused more and more concern. A multitude of epidemiological surveys have been organized in Great Britain, Australia, Canada, and mainly in United States, and have attempted to evaluate scientifically the psychiatric morbidity of this population. This literature review reveals disparity of epidemiological methods in assessing the type and extent of mental illness among homeless adults. The lack of consensual definition of homelessness, the choice of different settings in which the research is organized (street, health centres, shelters), and the use of diverse instruments of psychiatric evaluation (diagnosis by clinician, by scale or by structured diagnostic interview) lead to a great disparity of the results. Thus, 1/3 of the homeless adults had prior history of psychiatric hospitalisation. Rates of psychosis range to 70% and it is estimated that 4% to 74% of the homeless persons suffer from affective disorders. Substance abuse disorder remains a problem for a significant number of these individuals, with a high frequency of dual diagnosis. Such divergent data highlight the anglo-saxon debate between those who accuse desinstitutionnalisation as a reason of homelessness, and those who blame the socioeconomic background.

The Role of Tourism and Recreation in the Spread of Non-Native Species: A Systematic Review and Meta-Analysis

PubMed Central

Anderson, Lucy G.; Rocliffe, Steve; Haddaway, Neal R.; Dunn, Alison M.

2015-01-01

Managing the pathways by which non-native species are introduced and spread is considered the most effective way of preventing species invasions. Tourism and outdoor recreation involve the frequent congregation of people, vehicles and vessels from geographically diverse areas. They are therefore perceived to be major pathways for the movement of non-native species, and ones that will become increasingly important with the continued growth of these sectors. However, a global assessment of the relationship between tourism activities and the introduction of non-native species–particularly in freshwater and marine environments–is lacking. We conducted a systematic review and meta-analysis to determine the impact of tourism and outdoor recreation on non-native species in terrestrial, marine and freshwater environments. Our results provide quantitative evidence that the abundance and richness of non-native species are significantly higher in sites where tourist activities take place than in control sites. The pattern was consistent across terrestrial, freshwater and marine environments; across a variety of vectors (e.g. horses, hikers, yachts); and across a range of taxonomic groups. These results highlight the need for widespread biosecurity interventions to prevent the inadvertent introduction of invasive non-native species (INNS) as the tourism and outdoor recreation sectors grow. PMID:26485300

The Role of Tourism and Recreation in the Spread of Non-Native Species: A Systematic Review and Meta-Analysis.

PubMed

Anderson, Lucy G; Rocliffe, Steve; Haddaway, Neal R; Dunn, Alison M

2015-01-01

Managing the pathways by which non-native species are introduced and spread is considered the most effective way of preventing species invasions. Tourism and outdoor recreation involve the frequent congregation of people, vehicles and vessels from geographically diverse areas. They are therefore perceived to be major pathways for the movement of non-native species, and ones that will become increasingly important with the continued growth of these sectors. However, a global assessment of the relationship between tourism activities and the introduction of non-native species-particularly in freshwater and marine environments-is lacking. We conducted a systematic review and meta-analysis to determine the impact of tourism and outdoor recreation on non-native species in terrestrial, marine and freshwater environments. Our results provide quantitative evidence that the abundance and richness of non-native species are significantly higher in sites where tourist activities take place than in control sites. The pattern was consistent across terrestrial, freshwater and marine environments; across a variety of vectors (e.g. horses, hikers, yachts); and across a range of taxonomic groups. These results highlight the need for widespread biosecurity interventions to prevent the inadvertent introduction of invasive non-native species (INNS) as the tourism and outdoor recreation sectors grow.

Religious affiliation and under-five mortality in Mozambique.

PubMed

Cau, Boaventura M; Sevoyan, Arusyak; Agadjanian, Victor

2013-05-01

The influence of religion on health remains a subject of considerable debate both in developed and developing settings. This study examines the connection between the religious affiliation of the mother and under-five mortality in Mozambique. It uses unique retrospective survey data collected in a predominantly Christian area in Mozambique to compare under-five mortality between children of women affiliated to organized religion and children of non-affiliated women. It finds that mother's affiliation to any religious organization, as compared with non-affiliation, has a significant positive effect on child survival net of education and other socio-demographic factors. When the effects of affiliation to specific denominational groups are examined, only affiliation to the Catholic or mainstream Protestant churches and affiliation to Apostolic churches are significantly associated with improved child survival. It is argued that the advantages of these groups may be achieved through different mechanisms: the favourable effect on child survival of having mothers affiliated to the Catholic or mainstream Protestant churches is probably due to these churches' stronger connections to the health sector, while the beneficial effect of having an Apostolic mother is probably related to strong social ties and mutual support in Apostolic congregations. The findings thus shed light on multiple pathways through which organized religion can affect child health and survival in sub-Saharan Africa and similar developing settings.

Managing Conflict between Bats and Humans: The Response of Soprano Pipistrelles (Pipistrellus pygmaeus) to Exclusion from Roosts in Houses.

PubMed

Stone, Emma; Zeale, Matt R K; Newson, Stuart E; Browne, William J; Harris, Stephen; Jones, Gareth

2015-01-01

Conflict can arise when bats roost in human dwellings and householders are affected adversely by their presence. In the United Kingdom, the exclusion of bats from roosts can be licensed under exceptional circumstances to alleviate conflict, but the fate of excluded bats and the impact on their survival and reproduction is not well understood. Using radio-tracking, we investigated the effects of exclusion on the soprano pipistrelle Pipistrellus pygmaeus, a species that commonly roosts in buildings in Europe. Exclusions were performed under licence at five roosts in England in spring, when females were in the early stages of pregnancy. Following exclusion, all bats found alternative roosts and colonies congregated in nearby known roosts that had been used by radio-tagged bats prior to exclusion. We found no difference in roosting behaviour before and after exclusion. Both the frequency of roost switching and the type of roosts used by bats remained unchanged. We also found no change in foraging behaviour. Bats foraged in the same areas, travelled similar distances to reach foraging areas and showed similar patterns of habitat selection before and after exclusion. Population modelling suggested that any reduction in survival following exclusion could have a negative impact on population growth, whereas a reduction in productivity would have less effect. While the number of soprano pipistrelle exclusions currently licensed each year is likely to have little effect on local populations, the cumulative impacts of licensing the destruction of large numbers of roosts may be of concern.

Publication trend, resource utilization, and impact of the US National Cancer Database

PubMed Central

Su, Chang; Peng, Cuiying; Agbodza, Ena; Bai, Harrison X.; Huang, Yuqian; Karakousis, Giorgos; Zhang, Paul J.; Zhang, Zishu

2018-01-01

Abstract Background: The utilization and impact of the studies published using the National Cancer Database (NCDB) is currently unclear. In this study, we aim to characterize the published studies, and identify relatively unexplored areas for future investigations. Methods: A literature search was performed using PubMed in January 2017 to identify all papers published using NCDB data. Characteristics of the publications were extracted. Citation frequencies were obtained through the Web of Science. Results: Three hundred 2 articles written by 230 first authors met the inclusion criteria. The number of publications grew exponentially since 2013, with 108 articles published in 2016. Articles were published in 86 journals. The majority of the published papers focused on digestive system cancer, while bone and joints, eye and orbit, myeloma, mesothelioma, and Kaposi Sarcoma were never studied. Thirteen institutions in the United States were associated with more than 5 publications. The papers have been cited for a total of 9858 times since the publication of the first paper in 1992. Frequently appearing keywords congregated into 3 clusters: “demographics,” “treatments and survival,” and “statistical analysis method.” Even though the main focuses of the articles captured a extremely wide range, they can be classified into 2 main categories: survival analysis and characterization. Other focuses include database(s) analysis and/or comparison, and hospital reporting. Conclusion: The surging interest in the use of NCDB is accompanied by unequal utilization of resources by individuals and institutions. Certain areas were relatively understudied and should be further explored. PMID:29489679

Determinants of clergy behaviors promoting safety of battered Korean immigrant women.

PubMed

Choi, Y Joon

2015-03-01

Korean immigrants rely heavily on their respective churches for assistance with domestic violence. Yet, Korean clergy's responses to domestic violence are unknown. The purpose of this study was to examine factors that influence Korean clergy's responses to domestic violence in their congregations. Results showed that clergy's Korean cultural values, age, and length of residence in the United States influence their responses to domestic violence. Developing a collaborative working relationship between Korean clergy and domestic violence advocates, as well as providing training to Korean clergy targeting their knowledge, beliefs/attitudes, and skills is critical for promoting safety of battered Korean immigrant women. © The Author(s) 2015.

Colostomy irrigation: an important issue for Muslim individuals.

PubMed

Karadag, Ayise; Baykara, Zehra Göçmen

2009-01-01

Colostomy irrigation (CI) is a bowel management method in individuals with permanent colostomy, as an alternative to pouch use, which may provide continence. CI helps the individuals with an artificial stoma to adjust to the stoma and may increase their quality of life (QOL). An uncontrolled intestinal gas discharge invalidates ablution, and noisy gas discharge and smell prevents congregational prayers, which cause problems to Muslims with stomas. Therefore, CI may be an appropriate solution for this patient group. Using the example of one affected individual we discuss how the praying problem can be resolved with teaching to self-perform CI and emphasize the beneficial effects on QOL.

Employing the Church as a Marketer of Cancer Prevention

PubMed Central

Lumpkins, Crystal Y.; Coffey, Candice R.; Daley, Christine M.; Greiner, K. Allen

2013-01-01

Health promotion programs designed to address colorectal cancer disparities among African Americans are increasing. Unfortunately, this group still shoulders a disproportionate mortality burden in the United States; these numbers are also reflective of colorectal cancer (CRC) disparities in the Midwest. The purpose of this study was to extrapolate results from in-depth interviews and brief surveys on the effectiveness of the church as a social marketer of CRC-prevention messages. Results show that pastors believe the congregation has limited knowledge about CRC risk and prevention; they also believe the church can improve cancer-prevention communication among members and those affiliated with the church. PMID:23718957

Beyond Denomination: The Relationship between Religion and Family Planning in Rural Malawi

PubMed Central

Yeatman, Sara E.; Trinitapoli, Jenny

2010-01-01

Despite the centrality of religion and fertility to life in rural Africa, the relationship between the two remains poorly understood. The study presented here uses unique integrated individual and congregational level data from rural Malawi to examine religious influences on contraceptive use. In this religiously diverse population, we find evidence that the particular characteristics of a congregation—leader’s positive attitudes toward family planning and discussion of sexual morality, which do not fall along broad denominational lines—are more relevant than denominational categories for predicting women’s contraceptive use. We further find evidence for a relationship between religious socialization and contraceptive behavior. PMID:20463916

How culture shapes community: bible belief, theological unity, and a sense of belonging in religious congregations.

PubMed

Stroope, Samuel

2011-01-01

Feeling that you belong in a group is an important and powerful need. The ability to foster a sense of belonging can also determine whether groups survive. Organizational features of groups cultivate feelings of belonging, yet prior research fails to investigate the idea that belief systems also play a major role. Using multilevel data, this study finds that church members' traditional beliefs, group-level belief unity, and their interaction associate positively with members' sense of belonging. In fact, belief unity can be thought of as a “sacred canopy” under which the relationship between traditional beliefs and feelings of belonging thrives.

Reduction in Acute Gastroenteritis among Military Trainees: Secondary Effects of a Hygiene-based Cluster-Randomized Trial for Skin and Soft Tissue Infection Prevention

PubMed Central

D’Onofrio, Michael J.; Schlett, Carey D.; Millar, Eugene V.; Cui, Tianyuan; Lanier, Jeffrey B.; Law, Natasha N.; Tribble, David R.; Ellis, Michael W.

2018-01-01

Military personnel in congregate settings are at increased risk for acute gastroenteritis.1,2 Personal hygiene (eg, frequent hand washing, hand sanitizers, etc.) remains a central strategy. A skin and soft tissue infection (SSTI) prevention trial was conducted among military trainees.3 Trainees were randomized to 1 of 3 groups with incrementally increasing education- and hygiene-based measures. The principal components were promotion of hand washing in addition to a once-weekly application of a chlorhexidine-based body wash. Herein, we report the trial’s impact on acute gastroenteritis. PMID:25695181

Tuberculosis screening among homeless persons with AIDS living in single-room-occupancy hotels.

PubMed

Layton, M C; Cantwell, M F; Dorsinville, G J; Valway, S E; Onorato, I M; Frieden, T R

1995-11-01

Congregate facilities for homeless persons with the acquired immunodeficiency syndrome (AIDS) are often endemic for tuberculosis. We evaluated tuberculosis screening methods at single-room-occupancy hotels housing persons with AIDS. Residents were screened by cross matching the New York City Tuberculosis Registry, interviewing for tuberculosis history, skin testing, and chest radiography. Cases were classified as either previously or newly diagnosed. Among the 106 participants, 16 (15%) previously diagnosed tuberculosis cases were identified. Participants' tuberculosis histories were identified by the questionnaire (100%) or by registry match (69%). Eight participants (50%) were noncompliant with therapy. These findings prompted the establishment of a directly observed therapy program on site.

Indicators of commitment to the church: a longitudinal study of church-affiliated youth.

PubMed

Dudley, R L

1993-01-01

In an attempt to discover the factors that determine which late adolescents drop out of the church and which remain committed to it, a broad sample of Seventh-day Adventist youth was surveyed. These youth were part of a ten-year study which originally involved over 1,500 subjects distributed throughout the United States and Canada. Commitment was found to be related to cognitive, experiential, and activity dimensions of religion. Ethical considerations, a perception of one's importance to the local congregation, and peer influence also played a part in the stepwise regression package, which accounted for half of the variance in commitment scores.

Migratory culture, population structure and stock identity in North Pacific beluga whales (Delphinapterus leucas)

PubMed Central

Suydam, Robert; Quakenbush, Lori; Potgieter, Brooke; Harwood, Lois; Litovka, Dennis; Ferrer, Tatiana; Citta, John; Burkanov, Vladimir; Frost, Kathy; Mahoney, Barbara

2018-01-01

The annual return of beluga whales, Delphinapterus leucas, to traditional seasonal locations across the Arctic may involve migratory culture, while the convergence of discrete summering aggregations on common wintering grounds may facilitate outbreeding. Natal philopatry and cultural inheritance, however, has been difficult to assess as earlier studies were of too short a duration, while genetic analyses of breeding patterns, especially across the beluga’s Pacific range, have been hampered by inadequate sampling and sparse information on wintering areas. Using a much expanded sample and genetic marker set comprising 1,647 whales, spanning more than two decades and encompassing all major coastal summering aggregations in the Pacific Ocean, we found evolutionary-level divergence among three geographic regions: the Gulf of Alaska, the Bering-Chukchi-Beaufort Seas, and the Sea of Okhotsk (Φst = 0.11–0.32, Rst = 0.09–0.13), and likely demographic independence of (Fst-mtDNA = 0.02–0.66), and in many cases limited gene flow (Fst-nDNA = 0.0–0.02; K = 5–6) among, summering groups within regions. Assignment tests identified few immigrants within summering aggregations, linked migrating groups to specific summering areas, and found that some migratory corridors comprise whales from multiple subpopulations (PBAYES = 0.31:0.69). Further, dispersal is male-biased and substantial numbers of closely related whales congregate together at coastal summering areas. Stable patterns of heterogeneity between areas and consistently high proportions (~20%) of close kin (including parent-offspring) sampled up to 20 years apart within areas (G = 0.2–2.9, p>0.5) is the first direct evidence of natal philopatry to migration destinations in belugas. Using recent satellite telemetry findings on belugas we found that the spatial proximity of winter ranges has a greater influence on the degree of both individual and genetic exchange than summer ranges (rwinter-Fst-mtDNA = 0.9, rsummer-Fst-nDNA = 0.1). These findings indicate widespread natal philopatry to summering aggregation and entire migratory circuits, and provide compelling evidence that migratory culture and kinship helps maintain demographically discrete beluga stocks that can overlap in time and space. PMID:29566001

Seasonal spatial patterns in seabird and marine mammal distribution in the eastern Chukchi and western Beaufort seas: Identifying biologically important pelagic areas

NASA Astrophysics Data System (ADS)

Kuletz, Kathy J.; Ferguson, Megan C.; Hurley, Brendan; Gall, Adrian E.; Labunski, Elizabeth A.; Morgan, Tawna C.

2015-08-01

The Chukchi and Beaufort seas are undergoing rapid climate change and increased human activity. Conservation efforts for upper trophic level predators such as seabirds and marine mammals require information on species' distributions and identification of important marine areas. Here we describe broad-scale distributions of seabirds and marine mammals. We examined spatial patterns of relative abundance of seabirds and marine mammals in the eastern Chukchi and western Beaufort seas during summer (15 June-31 August) and fall (1 September-20 November) from 2007 to 2012. We summarized 49,206 km of shipboard surveys for seabirds and 183,157 km of aerial surveys for marine mammals into a grid of 40-km × 40-km cells. We used Getis-Ord Gi∗ hotspot analysis to test for cells with higher relative abundance than expected when compared to all cells within the study area. We identified cells representing single species and taxonomic group hotspots, cells representing hotspots for multiple species, and cells representing hotspots for both seabirds and marine mammals. The locations of hotspots varied among species but often were located near underwater canyons or over continental shelf features and slopes. Hotspots for seabirds, walrus, and gray whales occurred primarily in the Chukchi Sea. Hotspots for bowhead whales and other pinnipeds (i.e., seals) occurred near Barrow Canyon and along the Beaufort Sea shelf and slope. Hotspots for belugas occurred in both the Chukchi and Beaufort seas. There were three hotspots shared by both seabirds and marine mammals in summer: off Wainwright in the eastern Chukchi Sea, south of Hanna Shoal, and at the mouth of Barrow Canyon. In fall, the only identified shared hotspot occurred at the mouth of Barrow Canyon. Shared hotspots are characterized by strong fronts caused by upwelling and currents, and these areas can have high densities of euphausiids in summer and fall. Due to the high relative abundance of animals and diversity of taxa, these sites are clearly important areas of congregation for seabirds and marine mammals that should be prioritized in the development of management and conservation plans.

Migratory culture, population structure and stock identity in North Pacific beluga whales (Delphinapterus leucas).

PubMed

O'Corry-Crowe, Greg; Suydam, Robert; Quakenbush, Lori; Potgieter, Brooke; Harwood, Lois; Litovka, Dennis; Ferrer, Tatiana; Citta, John; Burkanov, Vladimir; Frost, Kathy; Mahoney, Barbara

2018-01-01

The annual return of beluga whales, Delphinapterus leucas, to traditional seasonal locations across the Arctic may involve migratory culture, while the convergence of discrete summering aggregations on common wintering grounds may facilitate outbreeding. Natal philopatry and cultural inheritance, however, has been difficult to assess as earlier studies were of too short a duration, while genetic analyses of breeding patterns, especially across the beluga's Pacific range, have been hampered by inadequate sampling and sparse information on wintering areas. Using a much expanded sample and genetic marker set comprising 1,647 whales, spanning more than two decades and encompassing all major coastal summering aggregations in the Pacific Ocean, we found evolutionary-level divergence among three geographic regions: the Gulf of Alaska, the Bering-Chukchi-Beaufort Seas, and the Sea of Okhotsk (Φst = 0.11-0.32, Rst = 0.09-0.13), and likely demographic independence of (Fst-mtDNA = 0.02-0.66), and in many cases limited gene flow (Fst-nDNA = 0.0-0.02; K = 5-6) among, summering groups within regions. Assignment tests identified few immigrants within summering aggregations, linked migrating groups to specific summering areas, and found that some migratory corridors comprise whales from multiple subpopulations (PBAYES = 0.31:0.69). Further, dispersal is male-biased and substantial numbers of closely related whales congregate together at coastal summering areas. Stable patterns of heterogeneity between areas and consistently high proportions (~20%) of close kin (including parent-offspring) sampled up to 20 years apart within areas (G = 0.2-2.9, p>0.5) is the first direct evidence of natal philopatry to migration destinations in belugas. Using recent satellite telemetry findings on belugas we found that the spatial proximity of winter ranges has a greater influence on the degree of both individual and genetic exchange than summer ranges (rwinter-Fst-mtDNA = 0.9, rsummer-Fst-nDNA = 0.1). These findings indicate widespread natal philopatry to summering aggregation and entire migratory circuits, and provide compelling evidence that migratory culture and kinship helps maintain demographically discrete beluga stocks that can overlap in time and space.

Response of religious groups to HIV/AIDS as a sexually transmitted infection in Trinidad

PubMed Central

Genrich, Gillian L; Brathwaite, Brader A

2005-01-01

Background HIV/AIDS-related stigma and discrimination are significant determinants of HIV transmission in the Caribbean island nation of Trinidad and Tobago (T&T), where the adult HIV/AIDS prevalence is 2.5%. T&T is a spiritually-aware society and over 104 religious groups are represented. This religious diversity creates a complex social environment for the transmission of a sexually transmitted infection like HIV/AIDS. Religious leaders are esteemed in T&T's society and may use their position and frequent interactions with the public to promote HIV/AIDS awareness, fight stigma and discrimination, and exercise compassion for people living with HIV/AIDS (PWHA). Some religious groups have initiated HIV/AIDS education programs within their membership, but previous studies suggest that HIV/AIDS remains a stigmatized infection in many religious organizations. The present study investigates how the perception of HIV/AIDS as a sexually transmitted infection impacts religious representatives' incentives to respond to HIV/AIDS in their congregations and communities. In correlation, the study explores how the experiences of PWHA in religious gatherings impact healing and coping with HIV/AIDS. Methods Between November 2002 and April 2003, in-depth interviews were conducted with 11 religious representatives from 10 Christian, Hindu and Muslim denominations. The majority of respondents were leaders of religious services, while two were active congregation members. Religious groups were selected based upon the methods of Brathwaite. Briefly, 26 religious groups with the largest followings according to 2000 census data were identified in Trinidad and Tobago. From this original list, 10 religious groups in Northwest Trinidad were selected to comprise a representative sample of the island's main denominations. In-depth interviews with PWHA were conducted during the same study period, 2002–2003. Four individuals were selected from a care and support group located in Port of Spain based upon their perceived willingness to discuss religious affiliation and describe how living with a terminal infection has affected their spiritual lives. The interviewer, a United States Fulbright Scholar, explained the nature and purpose of the study to all participants. Relevant ethical procedures associated with the collection of interview data were adopted: interviews were conducted in a non-coercive manner and confidentiality was assured. All participants provided verbal consent, and agreed to be interviewed without financial or other incentive. Ethics approval was granted on behalf of the Caribbean Conference of Churches Ethics Committee. Interview questions followed a guideline, and employed an open-ended format to facilitate discussion. All interviews were recorded and transcribed by the interviewer. Results Religious representatives' opinions were grouped into the following categories: rationale for the spread of HIV/AIDS, abstinence, condom use, sexuality and homosexuality, compassion, experiences with PWHA, recommendations and current approach to addressing HIV/AIDS in congregations. Religious representatives expressed a measure of acceptance of HIV/AIDS and overwhelmingly upheld compassion for PWHA. Some statements, however, suggested that HIV/AIDS stigma pervades Trinidad's religious organizations. For many representatives, HIV/AIDS was associated with a promiscuous lifestyle and/or homosexuality. Representatives had varying levels of interaction with PWHA, but personal experiences were positively associated with current involvement in HIV/AIDS initiatives. All 4 PWHA interviewed identified themselves as belonging to Christian denominations. Three out of the 4 PWHA described discriminatory experiences with pastors or congregation members during gatherings for religious services. Nonetheless, PWHA expressed an important role for faith and religion in coping with HIV. Conclusion Religious groups in Trinidad are being challenged to promote a clear and consistent response to the HIV/AIDS epidemic; a response that may reflect personal experiences and respect religious doctrine in the context of sex and sexuality. The study suggests that (1) religious leaders could improve their role in the fight against HIV/AIDS with education and sensitization-specifically aimed at dismantling the myths about HIV transmission, and the stereotyping of susceptible sub-populations, and (2) a consultative dialogue between PWHAs and religious leaders is pivotal to a successful faith-based HIV intervention in Trinidad. PMID:16288659

Turbulence and Cavitation Suppression by Quaternary Ammonium Salt Additives.

PubMed

Naseri, Homa; Trickett, Kieran; Mitroglou, Nicholas; Karathanassis, Ioannis; Koukouvinis, Phoevos; Gavaises, Manolis; Barbour, Robert; Diamond, Dale; Rogers, Sarah E; Santini, Maurizio; Wang, Jin

2018-05-16

We identify the physical mechanism through which newly developed quaternary ammonium salt (QAS) deposit control additives (DCAs) affect the rheological properties of cavitating turbulent flows, resulting in an increase in the volumetric efficiency of clean injectors fuelled with diesel or biodiesel fuels. Quaternary ammonium surfactants with appropriate counterions can be very effective in reducing the turbulent drag in aqueous solutions, however, less is known about the effect of such surfactants in oil-based solvents or in cavitating flow conditions. Small-angle neutron scattering (SANS) investigations show that in traditional DCA fuel compositions only reverse spherical micelles form, whereas reverse cylindrical micelles are detected by blending the fuel with the QAS additive. Moreover, experiments utilising X-ray micro computed tomography (micro-CT) in nozzle replicas, quantify that in cavitation regions the liquid fraction is increased in the presence of the QAS additive. Furthermore, high-flux X-ray phase contrast imaging (XPCI) measurements identify a flow stabilization effect in the region of vortex cavitation by the QAS additive. The effect of the formation of cylindrical micelles is reproduced with computational fluid dynamics (CFD) simulations by including viscoelastic characteristics for the flow. It is demonstrated that viscoelasticity can reduce turbulence and suppress cavitation, and subsequently increase the injector's volumetric efficiency.

A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells

PubMed Central

Chaikind, Brian; Bessen, Jeffrey L.; Thompson, David B.; Hu, Johnny H.; Liu, David R.

2016-01-01

We describe the development of ‘recCas9’, an RNA-programmed small serine recombinase that functions in mammalian cells. We fused a catalytically inactive dCas9 to the catalytic domain of Gin recombinase using an optimized fusion architecture. The resulting recCas9 system recombines DNA sites containing a minimal recombinase core site flanked by guide RNA-specified sequences. We show that these recombinases can operate on DNA sites in mammalian cells identical to genomic loci naturally found in the human genome in a manner that is dependent on the guide RNA sequences. DNA sequencing reveals that recCas9 catalyzes guide RNA-dependent recombination in human cells with an efficiency as high as 32% on plasmid substrates. Finally, we demonstrate that recCas9 expressed in human cells can catalyze in situ deletion between two genomic sites. Because recCas9 directly catalyzes recombination, it generates virtually no detectable indels or other stochastic DNA modification products. This work represents a step toward programmable, scarless genome editing in unmodified cells that is independent of endogenous cellular machinery or cell state. Current and future generations of recCas9 may facilitate targeted agricultural breeding, or the study and treatment of human genetic diseases. PMID:27515511