USDA-ARS?s Scientific Manuscript database
Soil organic matter (SOM) accumulation in paddy soils has aroused considerable attention due to its vital significance in global food, energy, climate, and environmental issues. Considerable progress has been made toward the understanding of changes in the quantity of SOM in paddy soils over a mille...
Project : semi-autonomous parking for enhanced safety and efficiency.
DOT National Transportation Integrated Search
2016-04-01
Index coding, a coding formulation traditionally analyzed in the theoretical computer science and : information theory communities, has received considerable attention in recent years due to its value in : wireless communications and networking probl...
ERIC Educational Resources Information Center
Yovanoff, Paul; Squires, Jane; McManus, Suzanne
2013-01-01
Adapting traditional paper-pencil instruments to computer-based environments has received considerable attention from the research community due to the possible administration mode effects on obtained measures. When differences due to mode of completion (i.e., paper-pencil, computer-based) are present, threats to measurement validity are posed. In…
Metal nanomaterials have attracted considerable attention because of their unique magnetic, optical, electrical, and catalytic properties and their potential applications in nanoelectronics. There is great interest in synthesizing metal nanoparticles due to their extraordinary pr...
Heterogeneous Activation Of Peroxymonosulfate With Iron-Cobalt Bimetallic Nanocatalysts
Sulfate radical-based advanced oxidation technologies (SR-AOTs) are attracting considerable attention due to the high oxidizing ability of sulfate radicals (SRs) to degrade various organic pollutants. It was found that SRs could be generated via homogeneous activation of peroxym...
The use of atomic force microscopy to evaluate warm mix asphalt : [executive summary report].
DOT National Transportation Integrated Search
2013-01-01
Warm Mix Asphalt (WMA) has received considerable attention in past few years due to its benefits in reducing energy consumption and pollutant emissions during production and placement of asphalt mixtures, as well as a compaction aid during the constr...
ERIC Educational Resources Information Center
Woodruff, Bruce E.
1976-01-01
A board member, says the Supreme Court, must be held to a standard of conduct based on knowledge of the basic unquestioned constitutional rights of his charges. The best defense against this serious liability threat is strict attention to due process and other relevant legal considerations. (Author/LBH)
Biotransformation of chlorinated aliphatic hydrocarbons under anaerobic conditions has received considerable attention due to the prevalence of these compounds as groundwater contaminants. However, information concerning the impact of mixtures of chlorinated compounds on their...
Applications and advances in electronic-nose technologies
A. D. Wilson; M. Baietto
2009-01-01
Electronic-nose devices have received considerable attention in the field of sensor technology during the past twenty years, largely due to the discovery of numerous applications derived from research in diverse fields of applied sciences. Recent applications of electronic nose technologies have come through advances in sensor design, material improvements, software...
Teachers' Perceptions of Student Evaluations of Teaching
ERIC Educational Resources Information Center
Chan, Cecilia K. Y.; Luk, Lillian Y. Y.; Zeng, Min
2014-01-01
Evaluation of teaching in higher education has drawn much attention due to the need for greater accountability and improvement in student learning. Our review of literature on Student Evaluation of Teaching (SET) surveys suggests that considerable controversy and criticism have surrounded its use, fairness, and validity. Yet, many universities in…
Population exposure to ambient particulate matter (PM) has received considerable attention due to the association between ambient particulate concentrations and mortality. Current toxicological studies and controlled human and animal exposures suggest that all size fractions of...
Differential host susceptibility to Batrachochytrium dendrobatidis, an emerging amphibian pathogen
C.L. Searle; S.S. Gervasi; J. Hua; J.I. Hammond; R.A. Relyea; D.H. Olson; A.R. Blaustein
2011-01-01
The amphibian fungal pathogen Batrachochytrium dendrobatidis (Bd) has received considerable attention due to its role in amphibian population declines worldwide. Although many amphibian species appear to be affected by Bd, there is little information on species-specific differences in susceptibility to this pathogen. We used a comparative...
Processing Trade-Offs in Non-Native Learners' Performance of Narrative Tasks
ERIC Educational Resources Information Center
Ben Maad, Mohamed Ridha
2011-01-01
Exploring learners' processes of memory and analysis has captivated considerable attention among language-learning researchers due to the recent prevalence of key concepts from feeder disciplines such as cognitive psychology and phraseology. However, there has been little empirical effort to describe the nature of interaction between these two…
USDA-ARS?s Scientific Manuscript database
The use of biostimulants to enhance crop production has gained considerable momentum because of its contribution to agroecological sustainability. Protein hydrolysates (PHs) are an important group of plant biostimulants that have received increasing attention in recent years due to their positive ef...
Essential considerations in developing attention control groups in behavioral research.
Aycock, Dawn M; Hayat, Matthew J; Helvig, Ashley; Dunbar, Sandra B; Clark, Patricia C
2018-06-01
Attention control groups strengthen randomized controlled trials of behavioral interventions, but researchers need to give careful consideration to the attention control activities. A comparative effectiveness research framework provides an ideal opportunity for an attention control group as a supplement to standard care, so participants potentially receive benefit regardless of group assignment. The anticipated benefit of the control condition must be independent of the study outcome. Resources needed for attention control activities need to be carefully considered and ethical considerations carefully weighed. In this paper we address nine considerations for the design and implementation of attention control groups: (1) ensure attention control activities are not associated with the outcome; (2) avoid contamination of the intervention or control group; (3) design comparable control and intervention activities; (4) ensure researcher training to adequately administer both treatment arms; (5) design control activities to be interesting and acceptable to participants; (6) evaluate attention control activities; (7) consider additional resources needed to implement attention control activities; (8) quantifying the effects of attention control and intervention groups; and (9) ethical considerations with attention control groups. Examples from the literature and ongoing research are presented. Careful planning for the attention control group is as important as for the intervention group. Researchers can use the considerations presented here to assist in planning for the best attention control group for their study. © 2018 Wiley Periodicals, Inc.
National Culture in Practice: Its Impact on Knowledge Sharing in Global Virtual Collaboration
ERIC Educational Resources Information Center
Wei, Kangning
2009-01-01
Issues concerning global virtual collaboration have received considerable attention in both the academic and practical world; however, little research has been conducted on knowledge-sharing activities in global virtual collaboration, which is a key process to achieve collaboration effectiveness. Due to national culture having been seen as one of…
Mechanical properties of wood fiber composites under the influence of temperature and humidity
Yibin Xue; David Veazie; Cindy Glinsey; Meagan Wright; Roger M. Rowell
2003-01-01
Woodfiber-thermoplastic composites (WPC) have received considerable attentions from the forest product industry for civil engineering applications due to its superior properties over wood and plastics alone. Particularly WPCs can be easily fabricated using traditional plastic processing techniques. The major limitation in the applications of WPCs is the poor...
USDA-ARS?s Scientific Manuscript database
Due to economic and environmental consequences of nitrogen (N) lost from fertilizer applications in corn (Zea mays L.), considerable public and industry attention has been devoted to development of N decision tools. Now a wide variety of tools are available to farmers for managing N inputs. However,...
Overview of a public-industry partnership for enhancing corn nitrogen research and datasets
USDA-ARS?s Scientific Manuscript database
Due to economic and environmental consequences of nitrogen (N) lost from fertilizer applications in corn (Zea mays L.), considerable public and industry attention has been devoted to development of N decision tools. Now a wide variety of tools are available to farmers for managing N inputs. However,...
ERIC Educational Resources Information Center
Shieh, Gwowen
2010-01-01
Due to its extensive applicability and computational ease, moderated multiple regression (MMR) has been widely employed to analyze interaction effects between 2 continuous predictor variables. Accordingly, considerable attention has been drawn toward the supposed multicollinearity problem between predictor variables and their cross-product term.…
Blending Technology with Constructivism: Implications for an ELT Classroom
ERIC Educational Resources Information Center
Kaya, Haldun
2015-01-01
The constructivist approach in learning a foreign language has been receiving a great deal of attention over the last years due to its tenets, which fully comply with the principles of the effective language learning environment. Taking the foundations of constructivist pedagogy into consideration, the most innovative attempt that English language…
USDA-ARS?s Scientific Manuscript database
A major skeletal problem of conventionally caged hens is increased susceptibility to osteoporosis mainly due to lack of exercise. Osteoporosis is characterized by a progressive decrease in mineralized structural bone. Whereas considerable attention has been given to enriching laying cages, little r...
ERIC Educational Resources Information Center
Yayeb, Aziza A.
2017-01-01
Universities receive a great deal of attention by governments due to its vast importance in development and economy. Productive type of universities are the most affective in this regard as they are producers of income, research, patents, intellectual activities, and good graduates. No wonder, they are always ranked highly among international…
Research-Based Interventions in the Area of Proof: The Past, the Present, and the Future
ERIC Educational Resources Information Center
Stylianides, Gabriel J.; Stylianides, Andreas J.
2017-01-01
The concept of "proof" has attracted considerable research attention over the past decades in part due to its indisputable importance to the discipline of mathematics and to students' learning of mathematics. Yet, the teaching and learning of proof is an instructionally arduous territory, with proof being recognized as a hard-to-teach…
Population exposure to ambient particulate matter (PM) has received considerable attention due to the association between ambient particulate concentrations and mortality. Current toxicological and epidemiological studies and controlled human and animal exposures suggest that a...
Manipulating the disengage operation of covert visual spatial attention.
Danckert, J; Maruff, P
1997-05-01
Processes of covert visual spatial attention have been closely linked to the programming of saccadic eye movements. In particular, it has been hypothesized that the reduction in saccadic latency that occurs in the gap paradigm is due to the prior disengagement of covert visual spatial attention. This explanation has received considerable criticism. No study as yet as attempted to demonstrate a facilitation of the disengagement of attention from a covertly attended object. If such facilitation were possible, it would support the hypothesis that the predisengagement of covert attention is necessary for the generation of express saccades. In two experiments using covert orienting of visual attention tasks (COVAT), with a high probability that targets would appear contralateral to the cued location, we attempted to facilitate the disengagement of covert attention by extinguishing peripheral cues prior to the appearance of targets. We hypothesized that the gap between cue offset and target onset would facilitate disengagement of attention from a covertly attended object. For both experiments, responses to targets appearing after a gap were slower than were responses in the no-gap condition. These results suggest that the prior offset of a covertly attended object does not facilitate the disengagement of attention.
Frölich, Jan; Banaschewski, Tobias; Döpfner, Manfred; Görtz-Dorten, Anja
2014-08-01
Methylphenidate (MPH) plays a principal role in the multimodal treatment of attention-deficit/hyperactivity disorder (ADHD). Controlled studies have demonstrated an effective reduction in the core symptoms of the disorder following MPH therapy, although long-term studies also demonstrate that the therapeutic benefits dissipate in the absence of combined psychosocial interventions. This review article focuses on the pharmacological characteristics of MPH, examining its effects on brain metabolism and the neurotransmitter system. Neuropsychological and clinical effects of different immediate and extended release MPH formulations are discussed to aid clinicians in choosing the appropriate formulation. The drug's addictive potency and abuse potential is also discussed. Data came from a literature search of relevant studies performed using the PubMed database up to June 2013. MPH is effective in the treatment of the core symptoms of ADHD. Considerable clinical expertise is required to identify an individually well-adapted dosage which will produce the optimal clinical effects with potential side effects minimized. Due to low adherence to medication, especially in adolescents, motivation to treatment and attentive clinical monitoring is mandatory, as is the consideration of risks of abuse or the presence of a comorbid addictive disorder.
Membrane interactions of ionic liquids and imidazolium salts.
Wang, Da; Galla, Hans-Joachim; Drücker, Patrick
2018-06-01
Room-temperature ionic liquids (RTILs) have attracted considerable attention in recent years due to their versatile properties such as negligible volatility, inflammability, high extractive selectivity and thermal stability. In general, RTILs are organic salts with a melting point below ~100 °C determined by the asymmetry of at least one of their ions. Due to their amphiphilic character, strong interactions with biological materials can be expected. However, rising attention has appeared towards their similarity and interaction with biomolecules. By employing structural modifications, the biochemical properties of RTILs can be designed to mimic lipid structures and to tune their hydrophobicity towards a lipophilic behavior. This is evident for the interaction with lipid-membranes where some of these compounds present membrane-disturbing effects or cellular toxicity. Moreover, they can form micelles or lipid-like bilayer structures by themselves. Both aspects, cellular effects and membrane-forming capacities, of a novel class of lipophilic imidazolium salts will be discussed.
On the analytical modeling of the nonlinear vibrations of pretensioned space structures
NASA Technical Reports Server (NTRS)
Housner, J. M.; Belvin, W. K.
1983-01-01
Pretensioned structures are receiving considerable attention as candidate large space structures. A typical example is a hoop-column antenna. The large number of preloaded members requires efficient analytical methods for concept validation and design. Validation through analyses is especially important since ground testing may be limited due to gravity effects and structural size. The present investigation has the objective to present an examination of the analytical modeling of pretensioned members undergoing nonlinear vibrations. Two approximate nonlinear analysis are developed to model general structural arrangements which include beam-columns and pretensioned cables attached to a common nucleus, such as may occur at a joint of a pretensioned structure. Attention is given to structures undergoing nonlinear steady-state oscillations due to sinusoidal excitation forces. Three analyses, linear, quasi-linear, and nonlinear are conducted and applied to study the response of a relatively simple cable stiffened structure.
Some Considerations on the Dynamics of Nanometric Suspensions in Fluid Media
NASA Astrophysics Data System (ADS)
Lungu, Mihai; Neculae, Adrian; Bunoiu, Madalin
2009-05-01
Nano-sized particles received considerable interest in the last decade. The manipulation of nanoparticles is becoming an important issue as they are more and more produced as a result of material synthesis and combustion emission. The nanometric particles represent a very important threat for human health because they can readily enter the human body through inhalation and their toxicity is relatively high due to the large specific surface area. The separation of the nano-sized particles into distinct bands, spatially separated one of each other had also brought recently considerable attention in many scientific areas; the usages of nanoparticles are very promising for the new technologies. The behavior of a suspension of sub-micronic particles under the action of dielectrophoretic force is numerically investigated and a theoretical model is proposed.
2011-11-01
Approved for public release; distribution unlimited. See additional restrictions described on inside pages STINFO COPY AIR...pin density, diameter and length are some of the parameters related to the effectiveness of z-pins for increasing the delamination resistance...has received considerable attention in recent years due to increased use of composite materials in aerospace and related industries. Mainly in the
[Outpatient medical attention demand due to diabetes mellitus in the health primary care].
Vázquez-Martínez, José Luis; Mercadillo-Pérez, María Guadalupe; Celis-Quintal, Juan Germán
2011-01-01
Outpatient visits for medical attention because of Diabetes mellitus in the Instituto Mexicano del Seguro Social became very important for the magnitude that it represents. There is a clear increasing tendency for the coming years. The available data indicates a higher frequency and increased demand of women. Higher number of patients is observed between 40 and 59 years old. However, earlier age groups present considerable amount of cases. Having the number of patients allows knowing the average of consultations per patient, this parameter allows having an estimate of the follow up by the physician and it must be part of the evaluation of the medical attention programs. Diabetes mellitus is strongly associated with obesity, this condition affects a high percentage of diabetic patients in the Institution and weight loss must be encouraged.
Influence of Lifestyle Factors on Breast Cancer Risk
Dieterich, Max; Stubert, Johannes; Reimer, Toralf; Erickson, Nicole; Berling, Anika
2014-01-01
Summary Breast Cancer (BC) is a life-changing event. Compared to other malignancies in women, BC has received considerably more public attention. Despite improved neoadjuvant, adjuvant, and palliative treatment strategies for each characteristic molecular BC subtype, recommendations for evidence-based preventive strategies for BC treatment are not given equivalent attention. This may be partly due to the fact that high-quality long-term prevention studies are still difficult to carry out and are thus underrepresented in international studies. The aim of this review is to discuss the most relevant lifestyle factors associated with BC and to identify and discuss the evidence supporting practical prevention strategies that can be used in everyday clinical practice. PMID:25759623
An Experimental Study of a Six Key Handprint Chord Keyboard.
1986-05-01
analysis: sequence time, list time, and errors, is better divided by group of tests, beginning or ending. This division forms a logical outline from which...accomplished pianists . Due to the limited amount of time at the keyboard that volunteers were willing to endure, asymptotic behavior was not reached...considerable attention , and it includes an idea of time 1152 quite different from that enunciated by Newton. According to this theory, 1226 there is no
Racial identity, aesthetic surgery and Yorùbá African Values.
Fayemi, Ademola K
2017-11-12
The question of racial identity in the process and outcome of aesthetic surgery is gaining increasing attention in bioethical discourse. This paper attempts an ethical examination of the racial identity issues involved in aesthetic surgery. Dominant moral values in Western culture are explored in the evaluation of aesthetic surgery. The paper argues that African values are yet to receive the universal attention they arguably deserve especially in the rethinking of values underlying aesthetic surgery as racial transformation. Through a consideration of some moral-aesthetic values in the Yorùbá-African culture, this paper further re-evaluates the ethics of aesthetic surgery. The paper contends against the propagation of aesthetic surgery as a new form of bolstering racial divides and identity in the evolving cosmopolitan age. The position defended in the paper is that some values from Yorùbá-African culture are useful in the consideration of the ethics of aesthetic surgery and more importantly, in avoiding the racial identity bias embedded in aesthetic surgery. The paper concludes that if due consideration is perhaps given to some African moral-aesthetic values in the global aesthetic surgery industry, some of the evolving moral and racial complexities would be better mediated. © 2017 John Wiley & Sons Ltd.
Java and its future in biomedical computing.
Rodgers, R P
1996-01-01
Java, a new object-oriented computing language related to C++, is receiving considerable attention due to its use in creating network-sharable, platform-independent software modules (known as "applets") that can be used with the World Wide Web. The Web has rapidly become the most commonly used information-retrieval tool associated with the global computer network known as the Internet, and Java has the potential to further accelerate the Web's application to medical problems. Java's potentially wide acceptance due to its Web association and its own technical merits also suggests that it may become a popular language for non-Web-based, object-oriented computing. PMID:8880677
A temporal phase unwrapping algorithm for photoelastic stress analysis
NASA Astrophysics Data System (ADS)
Baldi, Antonio; Bertolino, Filippo; Ginesu, Francesco
2007-05-01
Photoelastic stress analysis is a full-field optical technique for experimental stress analysis whose automation has received considerable research attention over the last 15 years. The latest developments have been made possible largely due to the availability of powerful calculators with large memory capacity and colour, high resolution, cameras. A further stimulus is provided by the photoelastic resins now used for rapid prototyping. However, one critical aspect which still deserves attention is phase unwrapping. The algorithms most commonly used for this purpose have been developed in other scientific areas (classical interferometry, profilometry, moiré, etc.) for solving different problems. In this article a new algorithm is proposed for temporal phase unwrapping, which offers several advantages over those used today.
Effect of composition and temperature on the second harmonic generation in silver phosphate glasses
NASA Astrophysics Data System (ADS)
Konidakis, I.; Psilodimitrakopoulos, S.; Kosma, K.; Lemonis, A.; Stratakis, E.
2018-01-01
We herein employ nonlinear laser imaging microscopy to explicitly study the dynamics of second harmonic generation (SHG) in silver iodide phosphate glasses. While glasses of this family have gained extensive scientific attention over the years due to their superior conducting properties, considerably less attention has been paid to their unique nonlinear optical characteristics. In the present study, firstly, it is demonstrated that SHG signal intensity is enhanced upon increasing silver content due to the random formation of silver microstructures within the glass network. Secondly, the SHG temperature dynamics were explored near the glass transition temperature (Tg) regime, where significant glass relaxation phenomena occur. It is found that heating towards the Tg improves the SHG efficiency, whereas above Tg, the capacity of glasses to generate second harmonic radiation is drastically suppressed. The novel findings of this work are considered important in terms of the potential employment of these glasses for the realization of advanced photonic applications like optical-switches and wavelength conversion devices.
Application of Microchip for Biomarker Analysis
NASA Astrophysics Data System (ADS)
Kataoka, Masatoshi; Yatsushiro, Shouki; Yamamura, Shouhei; Abe, Hiroko
Microchip technologies have received considerable attention, due to their competitive advantages, especially in regards to reduced sample and reagent consumption, analysis time, and easy operation. This approach has been successfully used to analyze DNA, amino acids, proteins, and carbohydrates. In the present study, we showed the potential of microchip technologies for the biomarker analysis, blood carbohydrate analysis on microchip electrophoresis, quantitative analysis of protein with antigen-antibody reaction on microchip, and the detection of malaria-infected erythrocyte with a cell microarray chip.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhuang, Chunqiang, E-mail: chunqiang.zhuang@bjut.edu.cn; Li, Zhipeng; Lin, Songsheng
2015-10-15
The basic issue related to radial crack in ceramic thin films has received considerable attention due to the fact that the radial crack plays an important role in evaluating the toughness properties of ceramic materials. In this work, an atomic-scale new experimental evidence is clearly presented to reveal the counter-intuitive initiation, the nucleation and the propagation mechanism of the radial crack in Al-Cr-N ceramic thin films.
Are rare-earth nanoparticles suitable for in vivo applications?
Liu, Chunyan; Hou, Yi; Gao, Mingyuan
2014-10-29
Rare earth (RE) nanoparticles have attracted considerable attention due to their unique optical and magnetic properties associated with f-electrons. The recent accomplishments in RE nanoparticle synthesis have aroused great interest of scientists to further explore their biomedical applications. This Research News summarizes recent achievements in controlled synthesis of magnetic and luminescent RE nanoparticles, surface modification, and toxicity studies of RE nanomaterials, and highlights state-of-the-art in in vivo applications of RE nanoparticles. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Cannabidiol: an overview of some pharmacological aspects.
Mechoulam, Raphael; Parker, Linda A; Gallily, Ruth
2002-11-01
Over the past few years, considerable attention has focused on cannabidiol (CBD), a major nonpsychotropic constituent of cannabis. The authors present a review on the chemistry of CBD and discuss the anticonvulsive, antianxiety, antipsychotic, antinausea, and antirheumatoid arthritic properties of CBD. CBD does not bind to the known cannabinoid receptors, and its mechanism of action is yet unknown. It is possible that, in part at least, its effects are due to its recently discovered inhibition of anandamide uptake and hydrolysis and to its antioxidative effect.
Saba, Ain Us; Nawazish, Shamyla; Akhtar, Fahad; Rashid, Rehana; Mir, Sadullah; Nasir, Bushra; Afzal, Samina; Pervaiz, Fahad
2017-01-01
Over the past few years, considerable attention has been focused on carrageenan based bionanocomposites due to their multifaceted properties like biodegradability, biocompatibility, and nontoxicity. Moreover, these composites can be tailored according to the desired purpose by using different nanofillers. The role of ferromagnetic nanoparticles in drug delivery is also discussed here in detail. Moreover, this article also presents a short review of recent research on the different types of the carrageenan based bionanocomposites and applications. PMID:28303171
NASA Technical Reports Server (NTRS)
Yolken, H. Thomas; Matzkanin, George A.
2009-01-01
Because of their increasing utilization in structural applications, the nondestructive evaluation (NDE) of advanced fiber reinforced polymer composites continues to receive considerable research and development attention. Due to the heterogeneous nature of composites, the form of defects is often very different from a metal and fracture mechanisms are more complex. The purpose of this report is to provide an overview and technology assessment of the current state-of-the-art with respect to NDE of advanced fiber reinforced polymer composites.
The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation.
Buratti, Emanuele; Baralle, Francisco Ernesto
2010-01-01
Heterogeneous ribonucleoproteins (hnRNPs) are multifunctional RNA-binding proteins (RBPs) involved in many cellular processes. They participate in most gene expression pathways, from DNA replication and repair to mRNA translation. Among this class of proteins, TDP-43 (and more recently FUS/TLS) have received considerable attention due to their involvement in several neurodegenerative diseases. This finding has prompted many research groups to focus on the gene expression pathways that are regulated by these proteins. The results have uncovered a considerable complexity of TDP-43 and FUS/TLS functions due to the many independent mechanisms by which they may act to influence various cellular processes (such as DNA transcription, pre-mRNA splicing, mRNA export/import). The aim of this chapter will be to review especially some of the novel functions that have been uncovered, such as role in miRNA synthesis, regulation of transcript levels, and potential autoregulatory mechanisms in order to provide the basis for further investigations.
Spatial attention determines the nature of nonverbal number representation.
Hyde, Daniel C; Wood, Justin N
2011-09-01
Coordinated studies of adults, infants, and nonhuman animals provide evidence for two systems of nonverbal number representation: a "parallel individuation" system that represents individual items and a "numerical magnitude" system that represents the approximate cardinal value of a group. However, there is considerable debate about the nature and functions of these systems, due largely to the fact that some studies show a dissociation between small (1-3) and large (>3) number representation, whereas others do not. Using event-related potentials, we show that it is possible to determine which system will represent the numerical value of a small number set (1-3 items) by manipulating spatial attention. Specifically, when attention can select individual objects, an early brain response (N1) scales with the cardinal value of the display, the signature of parallel individuation. In contrast, when attention cannot select individual objects or is occupied by another task, a later brain response (P2p) scales with ratio, the signature of the approximate numerical magnitude system. These results provide neural evidence that small numbers can be represented as approximate numerical magnitudes. Further, they empirically demonstrate the importance of early attentional processes to number representation by showing that the way in which attention disperses across a scene determines which numerical system will deploy in a given context.
Phytochemicals for the Management of Melanoma
Pal, Harish Chandra; Hunt, Katherine Marchiony; Diamond, Ariana; Elmets, Craig A.; Afaq, Farrukh
2016-01-01
Melanoma claims approximately 80% of skin cancer-related deaths. Its life-threatening nature is primarily due to a propensity to metastasize. The prognosis for melanoma patients with distal metastasis is bleak, with median survival of six months even with the latest available treatments. The most commonly mutated oncogenes in melanoma are BRAF and NRAS accounting approximately 60% and 20% of cases, respectively. In malignant melanoma, accumulating evidence suggests that multiple signaling pathways are constitutively activated and play an important role in cell proliferation, cell survival, epithelial to mesenchymal transition, metastasis and resistance to therapeutic regimens. Phytochemicals are gaining considerable attention because of their low toxicity, low cost, and public acceptance as dietary supplements. Cell culture and animals studies have elucidated several cellular and molecular mechanisms by which phytochemicals act in the prevention and treatment of metastatic melanoma. Several promising phytochemicals, such as, fisetin, epigallocatechin-3-gallate, resveratrol, curcumin, proanthocyanidins, silymarin, apigenin, capsaicin, genistein, indole-3-carbinol, and luteolin are gaining considerable attention and found in a variety of fresh fruits, vegetables, roots, and herbs. In this review, we will discuss the preventive potential, therapeutic effects, bioavailability and structure activity relationship of these selected phytochemicals for the management of melanoma. PMID:26864554
Phytochemicals for the Management of Melanoma.
Pal, Harish Chandra; Hunt, Katherine Marchiony; Diamond, Ariana; Elmets, Craig A; Afaq, Farrukh
2016-01-01
Melanoma claims approximately 80% of skin cancer-related deaths. Its life-threatening nature is primarily due to a propensity to metastasize. The prognosis for melanoma patients with distal metastasis is bleak, with median survival of six months even with the latest available treatments. The most commonly mutated oncogenes in melanoma are BRAF and NRAS accounting approximately 60% and 20% of cases, respectively. In malignant melanoma, accumulating evidence suggests that multiple signaling pathways are constitutively activated and play an important role in cell proliferation, cell survival, epithelial to mesenchymal transition, metastasis and resistance to therapeutic regimens. Phytochemicals are gaining considerable attention because of their low toxicity, low cost, and public acceptance as dietary supplements. Cell culture and animals studies have elucidated several cellular and molecular mechanisms by which phytochemicals act in the prevention and treatment of metastatic melanoma. Several promising phytochemicals, such as, fisetin, epigallocatechin-3-gallate, resveratrol, curcumin, proanthocyanidins, silymarin, apigenin, capsaicin, genistein, indole-3-carbinol, and luteolin are gaining considerable attention and found in a variety of fresh fruits, vegetables, roots, and herbs. In this review, we will discuss the preventive potential, therapeutic effects, bioavailability and structure activity relationship of these selected phytochemicals for the management of melanoma.
New organic semiconductors with imide/amide-containing molecular systems.
Liu, Zitong; Zhang, Guanxin; Cai, Zhengxu; Chen, Xin; Luo, Hewei; Li, Yonghai; Wang, Jianguo; Zhang, Deqing
2014-10-29
Due to their high electron affinities, chemical and thermal stabilities, π-conjugated molecules with imide/amide frameworks have received considerable attentions as promising candidates for high-performance optoelectronic materials, particularly for organic semiconductors with high carrier mobilities. The purpose of this Research News is to give an overview of recent advances in development of high performance imide/amide based organic semiconductors for field-effect transistors. It covers naphthalene diimide-, perylene diimide- and amide-based conjugated molecules and polymers for organic semiconductors. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Xu, Kai; Olsen, Olav; Tzvetkova-Robev, Dorothea
The amyloid precursor protein (APP) has garnered considerable attention due to its genetic links to Alzheimer's disease. Death receptor 6 (DR6) was recently shown to bind APP via the protein extracellular regions, stimulate axonal pruning, and inhibit synapse formation. Here, we report the crystal structure of the DR6 ectodomain in complex with the E2 domain of APP and show that it supports a model for APP-induced dimerization and activation of cell surface DR6.
[Crisis management in pediatric anesthesia].
Takeuchi, Mamoru; Otsuka, Yoji; Taga, Naoyuki; Sato, Yuki; Iwai, Hidetaka; Okada, Osamu
2009-05-01
We describe the risk management of pediatric anesthesia. The most important risk management of pediatric anesthesia is airway and temperature management. Neonates and infants easily become hypoxic due to their insufficient functional residual capacity. Therefore airway management is most important not only during induction of anesthesia but also during maintenance of anesthesia and extubation. The management of patients' temperature, including control of room temperature should be taken into consideration. In addition, careful attention should be paid not to introduce air bubbles in any lines, especially in patients with congenital heart diseases.
Plasmids from Food Lactic Acid Bacteria: Diversity, Similarity, and New Developments
Cui, Yanhua; Hu, Tong; Qu, Xiaojun; Zhang, Lanwei; Ding, Zhongqing; Dong, Aijun
2015-01-01
Plasmids are widely distributed in different sources of lactic acid bacteria (LAB) as self-replicating extrachromosomal genetic materials, and have received considerable attention due to their close relationship with many important functions as well as some industrially relevant characteristics of the LAB species. They are interesting with regard to the development of food-grade cloning vectors. This review summarizes new developments in the area of lactic acid bacteria plasmids and aims to provide up to date information that can be used in related future research. PMID:26068451
The ferromagnetic shape-memory effect in Ni Mn Ga
NASA Astrophysics Data System (ADS)
Marioni, M. A.; O'Handley, R. C.; Allen, S. M.; Hall, S. R.; Paul, D. I.; Richard, M. L.; Feuchtwanger, J.; Peterson, B. W.; Chambers, J. M.; Techapiesancharoenkij, R.
2005-04-01
Active materials have long been used in the construction of sensors and devices. Examples are piezo-electric ceramics and shape memory alloys. The more recently developed ferromagnetic shape-memory alloys (FSMAs) have received considerable attention due to their large magnetic field-induced, reversible strains (up to 10%). In this article, we review the basic physical characteristics of the FSMA Ni-Mn-Ga (crystallography, thermal, mechanical and magnetic behavior). Also, we present some of the works currently under way in the areas of pulse-field and acoustic-assisted actuation, and vibration energy absorption.
Barkholtz, Heather M.; Liu, Di -Jia
2016-11-14
Over the past several years, metal-organic framework (MOF)-derived platinum group metal free (PGM-free) electrocatalysts have gained considerable attention due to their high efficiency and low cost as potential replacement for platinum in catalyzing oxygen reduction reaction (ORR). In this review, we summarize the recent advancements in design, synthesis and characterization of MOF-derived ORR catalysts and their performances in acidic and alkaline media. As a result, we also discuss the key challenges such as durability and activity enhancement critical in moving forward this emerging electrocatalyst science.
Xu, Kai; Olsen, Olav; Tzvetkova-Robev, Dorothea; ...
2015-04-02
The amyloid precursor protein (APP) has garnered considerable attention due to its genetic links to Alzheimer's disease. Death receptor 6 (DR6) was recently shown to bind APP via the protein extracellular regions, stimulate axonal pruning, and inhibit synapse formation. Here, we report the crystal structure of the DR6 ectodomain in complex with the E2 domain of APP and show that it supports a model for APP-induced dimerization and activation of cell surface DR6.
Krubiner, Carleigh B; Merritt, Maria W
2017-03-01
Conditional cash transfers (CCTs) present a promising approach to simultaneously tackle chronic poverty and poor health. While these programmes clearly embody beneficent aims, questions remain regarding the ethical design of CCTs. Limited guidance exists for the ethical evaluation of the defining feature of these programmes: the conditionalities. Drawing upon prominent public health ethics frameworks and social justice theories, this paper outlines five categories of morally relevant considerations that CCT programme designers should consider when assessing which behaviours or outcomes they select as conditionalities for payment: (1) likelihood of yielding desired health outcomes, (2) risks and burdens, (3) receptivity, (4) attainability and (5) indirect impacts and externalities. When evaluating potential conditionalities across these five categories of considerations, it is important to recognise that not all beneficiaries or subgroups of beneficiaries will fare equally on each. Given that most CCTs aim to reduce inequities and promote long-term health and prosperity for the most disadvantaged, it is critical to apply these considerations with due attention to how different segments of the beneficiary population will be differentially affected. Taken on balance, with due reflection on distributional effects, these five categories represent a comprehensive set of considerations for the moral analysis of specific conditionalities and will help ensure that CCT designers structure programmes in a way that is both morally sound and effective in achieving their goals. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Uncapher, Melina R; Rugg, Michael D
2008-02-01
Considerable evidence suggests that attentional resources are necessary for the encoding of episodic memories, but the nature of the relationship between attention and neural correlates of encoding is unclear. Here we address this question using functional magnetic resonance imaging and a divided-attention paradigm in which competition for different types of attentional resources was manipulated. Fifteen volunteers were scanned while making animacy judgments to visually presented words and concurrently performing one of three tasks on auditorily presented words: male/female voice discrimination (control task), 1-back voice comparison (1-back task), or indoor/outdoor judgment (semantic task). The 1-back and semantic tasks were designed to compete for task-generic and task-specific attentional resources, respectively. Using the "remember/know" procedure, memory for the study words was assessed after 15 min. In the control condition, subsequent memory effects associated with later recollection were identified in the left dorsal inferior frontal gyrus and in the left hippocampus. These effects were differentially attenuated in the two more difficult divided-attention conditions. The effects of divided attention seem, therefore, to reflect impairments due to limitations at both task-generic and task-specific levels. Additionally, each of the two more difficult divided-attention conditions was associated with subsequent memory effects in regions distinct from those showing effects in the control condition. These findings suggest the engagement of alternative encoding processes to those engaged in the control task. The overall pattern of findings suggests that divided attention can impact later memory in different ways, and accordingly, that different attentional resources, including task-generic and task-specific resources, make distinct contributions to successful episodic encoding.
Fear of knowledge: Clinical hypotheses in diagnostic and prognostic reasoning.
Chiffi, Daniele; Zanotti, Renzo
2017-10-01
Patients are interested in receiving accurate diagnostic and prognostic information. Models and reasoning about diagnoses have been extensively investigated from a foundational perspective; however, for all its importance, prognosis has yet to receive a comparable degree of philosophical and methodological attention, and this may be due to the difficulties inherent in accurate prognostics. In the light of these considerations, we discuss a considerable body of critical thinking on the topic of prognostication and its strict relations with diagnostic reasoning, pointing out the distinction between nosographic and pathophysiological types of diagnosis and prognosis, underlying the importance of the explication and explanation processes. We then distinguish between various forms of hypothetical reasoning applied to reach diagnostic and prognostic judgments, comparing them with specific forms of abductive reasoning. The main thesis is that creative abduction regarding clinical hypotheses in diagnostic process is very unlikely to occur, whereas this seems to be often the case for prognostic judgments. The reasons behind this distinction are due to the different types of uncertainty involved in diagnostic and prognostic judgments. © 2016 John Wiley & Sons, Ltd.
Aerodynamic design of a rotor blade for minimum noise radiation
NASA Technical Reports Server (NTRS)
Karamcheti, K.; Yu, Y. H.
1974-01-01
An analysis of the aerodynamic design of a hovering rotor blade for obtaining minimum aerodynamic rotor noise has been carried out. In this analysis, which is based on both acoustical and aerodynamic considerations, attention is given only to the rotational noise due to the pressure fluctuations on the blade surfaces. The lift distribution obtained in this analysis has different characteristics from those of the conventional distribution. The present distribution shows negative lift values over a quarter of the span from the blade tip, and a maximum lift at about the midspan. Results are presented to show that the noise field is considerably affected by the shape of the lift distribution along the blade and that noise reduction of about 5 dB may be obtained by designing the rotor blade to yield minimum noise.
Nutritional Considerations for Performance in Young Athletes
Smith, JohnEric W.; Holmes, Megan E.; McAllister, Matthew J.
2015-01-01
Nutrition is an integral component to any athletes training and performance program. In adults the balance between energy intake and energy demands is crucial in training, recovery, and performance. In young athletes the demands for training and performance remain but should be a secondary focus behind the demands associated with maintaining the proper growth and maturation. Research interventions imposing significant physiological loads and diet manipulation are limited in youth due to the ethical considerations related to potential negative impacts on the growth and maturation processes associated with younger individuals. This necessary limitation results in practitioners providing nutritional guidance to young athletes to rely on exercise nutrition recommendations intended for adults. While many of the recommendations can appropriately be repurposed for the younger athlete attention needs to be taken towards the differences in metabolic needs and physiological differences. PMID:26464898
ERIC Educational Resources Information Center
Harvey, Séamus A.; McKay, Michael T.
2017-01-01
Consideration of future consequences (CFC) is described as the attention that individuals pay to the potential outcomes of their behaviour, and how their behaviour is affected as a result of attention to these outcomes. Greater CFC has been associated with less alcohol use, thus indicating its potential utility in health-promotion initiatives. A…
Bulk properties of solution-synthesized chevron-like graphene nanoribbons.
Vo, Timothy H; Shekhirev, Mikhail; Lipatov, Alexey; Korlacki, Rafal A; Sinitskii, Alexander
2014-01-01
Graphene nanoribbons (GNRs) have received a great deal of attention due to their promise for electronic and optoelectronic applications. Several recent studies have focused on the synthesis of GNRs by the bottom-up approaches that could yield very narrow GNRs with atomically precise edges. One type of GNRs that has received a considerable attention is the chevron-like GNR with a very distinct periodic structure. Surface-assisted and solution-based synthetic approaches for the chevron-like GNRs have been developed, but their electronic properties have not been reported yet. In this work, we synthesized chevron-like GNRs in bulk by a solution-based method, characterized them by a number of spectroscopic techniques and measured their bulk conductivity. We demonstrate that solution-synthesized chevron-like GNRs are electrically conductive in bulk, which makes them a potentially promising material for applications in organic electronics and photovoltaics.
Ayahuasca in adolescence: a preliminary psychiatric assessment.
Da Silveira, Dartiu Xavier; Grob, Charles S; de Rios, Marlene Dobkin; Lopez, Enrique; Alonso, Luisa K; Tacla, Cristiane; Doering-Silveira, Evelyn
2005-06-01
Ayahuasca is believed to be harmless for those (including adolescents) drinking it within a religious setting. Nevertheless controlled studies on the mental/ psychiatric status of ritual hallucinogenic ayahuasca concoction consumers are still lacking. In this study, 40 adolescents from a Brazilian ayahuasca sect were compared with 40 controls matched on sex, age, and educational background for psychiatric symptomatology. Screening scales for depression, anxiety, alcohol consumption patterns (abuse), attentional problems, and body dysmorphic disorders were used. It was found that, compared to controls, considerable lower frequencies of positive scoring for anxiety, body dismorphism, and attentional problems were detected among ayahuasca-using adolescents despite overall similar psychopathological profiles displayed by both study groups. Low frequencies of psychiatric symptoms detected among adolescents consuming ayahuasca within a religious context may reflect a protective effect due to their religious affiliation. However further studies on the possible interference of other variables in the outcome are necessary.
NASA Astrophysics Data System (ADS)
Mantel, Anna; Engel, Susen; Nuissl, Henning
2018-03-01
The small town of Altena is among the fastest-shrinking cities in western Germany and has recently attracted national and international attention due to its "welcoming culture" for refugees. This can be understood within the context of the town's strategic urban development policies aiming to counter the demographic change. This article argues that a regeneration strategy directed towards immigration and integration can offer a chance for shrinking cities but is simultaneously faced with considerable challenges and uncertainties, which could be dealt with through an "integrative approach" to urban development.
A Consumer-Oriented Control Framework for Performance Analysis in Hybrid Electric Vehicles
Shaltout, Mohamed L.; Malikopoulos, Andreas A.; Pannala, Sreekanth; ...
2014-12-09
Hybrid electric vehicles (HEVs) have attracted considerable attention due to their potential to reduce fuel consumption and emissions. Our objective with this paper is to enhance our understanding of the associated tradeoffs among the HEV subsystems, e.g., the engine, the motor, and the battery, and investigate the related implications for fuel consumption and battery capacity and lifetime. Addressing this problem can provide insights on how to prioritize these objectives based on consumers needs and preferences. The results of the proposed optimization approach can also be used to investigate the implications for HEV costs related to ownership and warranty.
NASA Astrophysics Data System (ADS)
Mantel, Anna; Engel, Susen; Nuissl, Henning
2018-04-01
The small town of Altena is among the fastest-shrinking cities in western Germany and has recently attracted national and international attention due to its "welcoming culture" for refugees. This can be understood within the context of the town's strategic urban development policies aiming to counter the demographic change. This article argues that a regeneration strategy directed towards immigration and integration can offer a chance for shrinking cities but is simultaneously faced with considerable challenges and uncertainties, which could be dealt with through an "integrative approach" to urban development.
Magnetic Ordering in Sr 3YCo 4O 10+x
Kishida, Takayoshi; Kapetanakis, Myron D.; Yan, Jiaqiang; ...
2016-01-28
Transition-metal oxides often exhibit complex magnetic behavior due to the strong interplay between atomic-structure, electronic and magnetic degrees of freedom. Cobaltates, especially, exhibit complex behavior because of cobalt’s ability to adopt various valence and spin state configurations. The case of the oxygen-deficient perovskite Sr 3YCo 4O 10+x (SYCO) has gained considerable attention because of persisting uncertainties about its structure and the origin of the observed room temperature ferromagnetism. Here we report a combined investigation of SYCO using aberration-corrected scanning transmission electron microscopy and density functional theory calculations.
A knitted glove sensing system with compression strain for finger movements
NASA Astrophysics Data System (ADS)
Ryu, Hochung; Park, Sangki; Park, Jong-Jin; Bae, Jihyun
2018-05-01
Development of a fabric structure strain sensor has received considerable attention due to its broad application in healthcare monitoring and human–machine interfaces. In the knitted textile structure, it is critical to understand the surface structural deformation from a different body motion, inducing the electrical signal characteristics. Here, we report the electromechanical properties of the knitted glove sensing system focusing on the compressive strain behavior. Compared with the electrical response of the tensile strain, the compressive strain shows much higher sensitivity, stability, and linearity via different finger motions. Additionally, the sensor exhibits constant electrical properties after repeated cyclic tests and washing processes. The proposed knitted glove sensing system can be readily extended to a scalable and cost-effective production due to the use of a commercialized manufacturing system.
Okello, Edward J; Abadi, Awatf M; Abadi, Saad A
2016-06-01
Tea has been associated with many mental benefits, such as attention enhancement, clarity of mind, and relaxation. These psychosomatic states can be measured in terms of brain activity using an electroencephalogram (EEG). Brain activity can be assessed either during a state of passive activity or when performing attention tasks and it can provide useful information about the brain's state. This study investigated the effects of green and black consumption on brain activity as measured by a simplified EEG, during passive activity. Eight healthy volunteers participated in the study. The EEG measurements were performed using a two channel EEG brain mapping instrument - HeadCoach™. Fast Fourier transform algorithm and EEGLAB toolbox using the Matlab software were used for data processing and analysis. Alpha, theta, and beta wave activities were all found to increase after 1 hour of green and black tea consumption, albeit, with very considerable inter-individual variations. Our findings provide further evidence for the putative beneficial effects of tea. The highly significant increase in theta waves (P < 0.004) between 30 minutes and 1 hour post-consumption of green tea may be an indication of its putative role in cognitive function, specifically alertness and attention. There were considerable inter-individual variations in response to the two teas which may be due genetic polymorphisms in metabolism and/or influence of variety/blend, dose and content of the selected products whose chemistry and therefore efficacy will have been influenced by 'from field to shelf practices'.
Hydrogel scaffolds for tissue engineering: Progress and challenges
El-Sherbiny, Ibrahim M.; Yacoub, Magdi H.
2013-01-01
Designing of biologically active scaffolds with optimal characteristics is one of the key factors for successful tissue engineering. Recently, hydrogels have received a considerable interest as leading candidates for engineered tissue scaffolds due to their unique compositional and structural similarities to the natural extracellular matrix, in addition to their desirable framework for cellular proliferation and survival. More recently, the ability to control the shape, porosity, surface morphology, and size of hydrogel scaffolds has created new opportunities to overcome various challenges in tissue engineering such as vascularization, tissue architecture and simultaneous seeding of multiple cells. This review provides an overview of the different types of hydrogels, the approaches that can be used to fabricate hydrogel matrices with specific features and the recent applications of hydrogels in tissue engineering. Special attention was given to the various design considerations for an efficient hydrogel scaffold in tissue engineering. Also, the challenges associated with the use of hydrogel scaffolds were described. PMID:24689032
Delusion in general and forensic psychiatry--historical and contemporary aspects.
Hoff, Paul
2006-01-01
Delusion has always been a central topic for psychiatric research with regard to etiology and pathogenesis and to diagnosis, treatment, and forensic relevance. Throughout the history of psychiatry as a scientific discipline, there has been dissent on the issue of whether chronic delusion is a nosological entity of its own or just a specific type of another mental disorder, e.g. schizophrenia, mania, or personality disorder, and there already is a considerable literature on this. This article seeks to elucidate the central lines of thought that have governed the scientific debate on delusions and delusion-associated phenomena since the early 19th century. Special attention is given to the practical relevance of these theoretical considerations for forensic questions and psychiatric research. Due to the complex features of delusions, research in this area may well become paradigmatic for many other complicated psycho(patho)logical phenomena, e.g. consciousness, hallucinations and psychotic depression.
College Students' Attention Behaviors during Independent Study and Course Level Academic Performance
ERIC Educational Resources Information Center
Wagner, Linda G.
2012-01-01
Students in college make daily choices about how to use their independent study time, including choices about allocation of attention. Based on theoretical considerations and clinical studies, attention and the dividing of attention through multitasking is thought to have a relationship to performance levels. Research is only beginning to explore,…
Indications and Warning Analysis Management System IWAMS. A Design Study
1980-03-01
First, we must understand the process of warning analysis; we must develop an -;adequate functional model. In the present research we have divided ...and changeable). (In subsequent discussions, considerable attention will be focused on these issues.) -77-7-12Z ’m,77+-U 21 WARNING ANALYSIS MODEL...have charted limitations in man’s memory, attention span, reasoning capability and other cognitive functions. These limitations considerably affect man’s
Genetic and metabolic engineering in diatoms.
Huang, Weichao; Daboussi, Fayza
2017-09-05
Diatoms have attracted considerable attention due to their success in diverse environmental conditions, which probably is a consequence of their complex origins. Studies of their metabolism will provide insight into their adaptation capacity and are a prerequisite for metabolic engineering. Several years of investigation have led to the development of the genome engineering tools required for such studies, and a profusion of appropriate tools is now available for exploring and exploiting the metabolism of these organisms. Diatoms are highly prized in industrial biotechnology, due to both their richness in natural lipids and carotenoids and their ability to produce recombinant proteins, of considerable value in diverse markets. This review provides an overview of recent advances in genetic engineering methods for diatoms, from the development of gene expression cassettes and gene delivery methods, to cutting-edge genome-editing technologies. It also highlights the contributions of these rapid developments to both basic and applied research: they have improved our understanding of key physiological processes; and they have made it possible to modify the natural metabolism to favour the production of specific compounds or to produce new compounds for green chemistry and pharmaceutical applications.This article is part of the themed issue 'The peculiar carbon metabolism in diatoms'. © 2017 The Author(s).
Dye-Enhanced Self-Electrophoretic Propulsion of Light-Driven TiO2-Au Janus Micromotors
NASA Astrophysics Data System (ADS)
Wu, Yefei; Dong, Renfeng; Zhang, Qilu; Ren, Biye
2017-07-01
Light-driven synthetic micro-/nanomotors have attracted considerable attention in recent years due to their unique performances and potential applications. We herein demonstrate the dye-enhanced self-electrophoretic propulsion of light-driven TiO2-Au Janus micromotors in aqueous dye solutions. Compared to the velocities of these micromotors in pure water, 1.7, 1.5, and 1.4 times accelerated motions were observed for them in aqueous solutions of methyl blue (10-5 g L-1), cresol red (10-4 g L-1), and methyl orange (10-4 g L-1), respectively. We determined that the micromotor speed changes depending on the type of dyes, due to variations in their photodegradation rates. In addition, following the deposition of a paramagnetic Ni layer between the Au and TiO2 layers, the micromotor can be precisely navigated under an external magnetic field. Such magnetic micromotors not only facilitate the recycling of micromotors, but also allow reusability in the context of dye detection and degradation. In general, such photocatalytic micro-/nanomotors provide considerable potential for the rapid detection and "on-the-fly" degradation of dye pollutants in aqueous environments.
Liu, Chunyi; Wang, Xusheng; Deng, Wenjun; Li, Chang; Chen, Jitao; Xue, Mianqi; Li, Rui; Pan, Feng
2018-03-14
The rechargeable aqueous metal-ion battery (RAMB) has attracted considerable attention due to its safety, low costs, and environmental friendliness. Yet the poor-performance electrode materials lead to a low feasibility of practical application. A hybrid aqueous battery (HAB) built from electrode materials with selective cation channels could increase the electrode applicability and thus enlarge the application of RAMB. Herein, we construct a high-voltage K-Na HAB based on K 2 FeFe(CN) 6 cathode and carbon-coated NaTi 2 (PO 4 ) 3 (NTP/C) anode. Due to the unique cation selectivity of both materials and ultrafast ion conduction of NTP/C, the hybrid battery delivers a high capacity of 160 mAh g -1 at a 0.5 C rate. Considerable capacity retention of 94.3 % is also obtained after 1000 cycles at even 60 C rate. Meanwhile, high energy density of 69.6 Wh kg -1 based on the total mass of active electrode materials is obtained, which is comparable and even superior to that of the lead acid, Ni/Cd, and Ni/MH batteries. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
The development of low-molecular weight hydrogels for applications in cancer therapy
NASA Astrophysics Data System (ADS)
Tian, Ran; Chen, Jin; Niu, Runfang
2014-03-01
To improve the anti-cancer efficacy and to counteract the side effects of chemotherapy, a variety of drug delivery systems have been invented in past decades, but few of these systems have succeeded in clinical trials due to their respective inherent shortcomings. Recently, low-molecular weight hydrogels of peptides that self-assemble via non-covalent interactions have attracted considerable attention due to their good biocompatibility, low toxicity, inherent biodegradability as well as their convenience of design. Low-molecular weight hydrogels have already shown promise in biomedical applications as diverse as 3D-cell culture, enzyme immobilization, controllable MSC differentiation, wound healing, drug delivery etc. Here we review the recent development in the use of low-molecular weight hydrogels for cancer therapy, which may be helpful in the design of soft materials for drug delivery.
NASA Astrophysics Data System (ADS)
Shao, Xinxing; Zhu, Feipeng; Su, Zhilong; Dai, Xiangjun; Chen, Zhenning; He, Xiaoyuan
2018-03-01
The strain errors in stereo-digital image correlation (DIC) due to camera calibration were investigated using precisely controlled numerical experiments and real experiments. Three-dimensional rigid body motion tests were conducted to examine the effects of camera calibration on the measured results. For a fully accurate calibration, rigid body motion causes negligible strain errors. However, for inaccurately calibrated camera parameters and a short working distance, rigid body motion will lead to more than 50-μɛ strain errors, which significantly affects the measurement. In practical measurements, it is impossible to obtain a fully accurate calibration; therefore, considerable attention should be focused on attempting to avoid these types of errors, especially for high-accuracy strain measurements. It is necessary to avoid large rigid body motions in both two-dimensional DIC and stereo-DIC.
Surgical techniques for the treatment of carpal ligament injury in the athlete.
Paci, Gabrielle M; Yao, Jeffrey
2015-01-01
Treatment of intercarpal ligament injuries in the athlete requires special attention due to several practical and biomechanical considerations. Optimally, the athlete will maintain as much function and range of motion as possible with return to high-impact and load-bearing activity in a timely fashion. Several cutting-edge techniques have arisen in treatment. This article discusses injury patterns in the athlete with scapholunate injury, lunotriquetral injury, scaphotrapezial-trapezoidal injury, and extrinsic ligamentous injury, and the various approaches to addressing these injuries, with a review of the classic as well as newer, innovative techniques. Copyright © 2015 Elsevier Inc. All rights reserved.
Electron Capture in Slow Collisions of Si4+ With Atomic Hydrogen
NASA Astrophysics Data System (ADS)
Joseph, D. C.; Gu, J. P.; Saha, B. C.
2009-10-01
In recent years the charge transfer involving Si4+ and H at low energies has drawn considerable attention both theoretically and experimentally due to its importance not only in astronomical environments but also in modern semiconductor industries. Accurate information regarding its molecular structures and interactions are essential to understand the low energy collision dynamics. Ab initio calculations are performed using the multireference single- and double-excitation configuration-interaction (MRD-CI) method to evaluate potential energies. State selective cross sections are calculate using fully quantum and semi-classical molecular-orbital close coupling (MOCC) methods in the adiabatic representation. Detail results will be presented in the conference.
Microwave-assisted efficient conjugation of nanodiamond and paclitaxel.
Hsieh, Yi-Han; Liu, Kuang-Kai; Sulake, Rohidas S; Chao, Jui-I; Chen, Chinpiao
2015-01-01
Nanodiamond has recently received considerable attention due to the various possible applications in medical field such as drug delivery and bio-labeling. For this purpose suitable and effective surface functionalization of the diamond material are required. A versatile and reproducible surface modification method of nanoscale diamond is essential for functionalization. We introduce the input of microwave energy to assist the functionalization of nanodiamond surface. The feasibility of such a process is illustrated by comparing the biological assay of ND-paclitaxel synthesized by conventional and microwave irradiating. Using a microwave we manage to have approximately doubled grafted molecules per nanoparticle of nanodiamond. Copyright © 2015 Elsevier Ltd. All rights reserved.
Emerging applications of conjugated polymers in molecular imaging.
Li, Junwei; Liu, Jie; Wei, Chen-Wei; Liu, Bin; O'Donnell, Matthew; Gao, Xiaohu
2013-10-28
In recent years, conjugated polymers have attracted considerable attention from the imaging community as a new class of contrast agent due to their intriguing structural, chemical, and optical properties. Their size and emission wavelength tunability, brightness, photostability, and low toxicity have been demonstrated in a wide range of in vitro sensing and cellular imaging applications, and have just begun to show impact in in vivo settings. In this Perspective, we summarize recent advances in engineering conjugated polymers as imaging contrast agents, their emerging applications in molecular imaging (referred to as in vivo uses in this paper), as well as our perspectives on future research.
The high producing dairy cow and its reproductive performance
Dobson, H; Smith, RF; Royal, MD; Knight, CH; Sheldon, IM
2009-01-01
Contents: Intensive genetic selection has resulted in modern dairy cow with very high milk yields but reduced fertility, due mainly to an increase in postpartum clinical problems, poor expression of oestrus, defective oocytes/embryos and uterine infections. It is a challenge to get enough food into these cows to meet the high demands of peak milk yields in early lactation and the animals require considerable veterinary attention in the early period after calving. Both genetic and management changes to increase the persistency of lactations would reduce the number and intensity of clinical risk periods throughout a cow's life without compromising milk output. PMID:17688598
Koonrungsesomboon, Nut; Karbwang, Juntra
2016-10-15
Cardiovascular disease (CVD) in the ageing is a major public health problem worldwide. The nature of most CVD is subclinical with pathological processes that can span over years. Use of preventive measures could be an appropriate approach to prevailing over CVD in the ageing, and herbal medicine is one of the promising preventive approaches and is currently of interest among medical societies. In the evidence-based era, herbal medicine is, however, often underestimated and approached with skepticism, mainly due to the paucity of scientific evidence. Properly designed clinical trials on herbal medicine for prevention of CVD in a geriatric population are thus of importance and of clinical value. To review ethical issues and discuss considerations when such research is proposed. Four ethical issues, including the scientific validity of research, risk-benefit assessments, subject selection and vulnerability, and informed consent, are structured and extensively discussed in this article. Ethical core considerations of prevention research of CVD on herbal medicine involve particular attention on the scientific validity of research, risk-benefit assessments, subject selection and vulnerability, and informed consent. These issues and considerations are keys, although they must be adapted to an individual research setting in which a clinical study is proposed. Copyright © 2015 Elsevier GmbH. All rights reserved.
How Can We Second-Guess Attention in the Classroom; A Physiological Answer.
ERIC Educational Resources Information Center
Fletcher, James E.
In preparing instructional materials, consideration must be given to the students' attention. Carl Hagfors has conducted a number of experiments measuring the electrodermal response simultaneously from a number of subjects viewing the same materials. When most subjects were attentive there was a large discursion of the recorder pen. When some were…
ERIC Educational Resources Information Center
Jitendra, Asha K.; DuPaul, George J.; Someki, Fumio; Tresco, Katy E.
2008-01-01
Although children with Attention-Deficit Hyperactivity Disorder (ADHD) exhibit significant academic difficulties in school settings, considerably less attention is devoted to remediating their academic problems when compared to behavioral and social difficulties. The purpose of this article is to review empirically supported academic interventions…
ERIC Educational Resources Information Center
Bastable, C. W.; Brady, Gerald P.
1976-01-01
Complexities in managing TIAA-CREF contracts are reviewed. Attention is directed toward participation, period considerations, selection of retirement age, retirement income transition, estate considerations and beneficiaries, voluntary additional contributions, and supplemental retirement annuity contracts. (LBH)
Methodology for evaluation of railroad technology research projects
DOT National Transportation Integrated Search
1981-04-01
This Project memorandum presents a methodology for evaluating railroad research projects. The methodology includes consideration of industry and societal benefits, with special attention given to technical risks, implementation considerations, and po...
Collins, Dave; Carson, Howie J; Toner, John
2016-01-01
Abdollahipour, Wulf, Psotta, and Nieto (2015) recently published data in the Journal of Sports Sciences to show that an external focus of attention promotes superior performance effects (gymnastics jump height and judged movement form score) when compared to internal or control foci during skill execution without an implement involved. While we do not contest the veracity of findings reported, nor others that have been used to support beneficial effects of an external focus of attention, in this Letter to the Editor we comment on considerable methodological limitations associated with this and previous studies that, we suggest, have resulted in serious theoretical oversights regarding the control of movement and, most crucially from our practitioner perspective, suboptimal recommendations for applied coaching practice. Specifically, we discuss the lack of consideration towards translational research in this area, the problematic nature of attentional focus cues employed, interpretation of findings in relation to other applied recommendations and coherence with mechanistic underpinning and, finally, the representative nature of task involved. In summary, while (laboratory) research evidence may appear to be conclusive, we suggest that the focus of attention effects are in need of more ecologically valid and rigorous testing as well as consideration of current coaching practices if it is to optimally serve the applied sporting domain that it purportedly aims to.
NASA Astrophysics Data System (ADS)
Lin, Yu; He, Rong; Sun, Liping; Yang, Yushan; Li, Wenqing; Sun, Fei
2016-12-01
Gold-based nanocrystals have attracted considerable attention for drug delivery and biological applications due to their distinct shapes. However, overcoming biological barriers is a hard and inevitable problem, which restricts medical applications of nanomaterials in vivo. Seeking for an efficient transportation to penetrate biological barriers is a common need. There are three barriers: blood-testis barrier, blood-placenta barrier, and blood-brain barrier. Here, we pay close attention to the blood-testis barrier. We found that the pentacle gold-copper alloy nanocrystals not only could enter GC-2 cells in vitro in a short time, but also could overcome the blood-testis barrier and enter male germ cells in vivo. Furthermore, we demonstrated that the entrance efficiency would become much higher in the development stages. The results also suggested that the pentacle gold-copper alloy nanocrystals could easier enter to germ cells in the pathological condition. This system could be a new method for theranostics in the reproductive system.
Recent Progress on Flexible and Wearable Supercapacitors.
Xue, Qi; Sun, Jinfeng; Huang, Yan; Zhu, Minshen; Pei, Zengxia; Li, Hongfei; Wang, Yukun; Li, Na; Zhang, Haiyan; Zhi, Chunyi
2017-12-01
Recently, wearable electronic devices including electrical sensors, flexible displays, and health monitors have received considerable attention and experienced rapid progress. Wearable supercapacitors attract tremendous attention mainly due to their high stability, low cost, fast charging/discharging, and high efficiency; properties that render them value for developing fully flexible devices. In this Concept, the recent achievements and advances made in flexible and wearable supercapacitors are presented, especially highlighting the promising performances of yarn/fiber-shaped and planar supercapacitors. On the basis of their working mechanism, electrode materials including carbon-based materials, metal oxide-based materials, and conductive polymers with an emphasis on the performance-optimization method are introduced. The latest representative techniques and active materials of recently developed supercapacitors with superior performance are summarized. Furthermore, the designs of 1D and 2D electrodes are discussed according to their electrically conductive supporting materials. Finally, conclusions, challenges, and perspective in optimizing and developing the electrochemical performance and function of wearable supercapacitors for their practical utility are addressed. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Weed, Elizabeth D
Attention-deficit/hyperactivity disorder is considered one of the most common neurodevelopmental disorders of childhood. Primary care providers are in the unique position of providing comprehensive care-routine care, well child visits, immunizations, and other healthcare needs-to a majority of children and adolescents with attention-deficit/hyperactivity disorder. As such, primary care providers are pivotal in the diagnosis, management, and treatment of this population. This article will address special treatment considerations to aid in the management of attention-deficit/hyperactivity disorder in the primary care setting, including substance use disorders and diversion, cardiac issues and stimulant medication, medication holidays and follow-up monitoring. The database of PubMed was searched using keywords that included attention-deficit/hyperactivity disorder, children, prevalence, medication holidays, safety, cardiovascular, cardiac, blood pressure, substance use, diversion, adverse drug reactions; inclusion dates were January 1, 2011 to September 30, 2015. © The Author(s) 2016.
NASA Astrophysics Data System (ADS)
Anton, S. R.; Erturk, A.; Inman, D. J.
2010-04-01
Vibration energy harvesting has received considerable attention in the research community over the past decade. Typical vibration harvesting systems are designed to be added on to existing host structures and capture ambient vibration energy. An interesting application of vibration energy harvesting exists in unmanned aerial vehicles (UAVs), where a multifunctional approach, as opposed to the traditional method, is needed due to weight and aerodynamic considerations. The authors propose a multifunctional design for energy harvesting in UAVs where the piezoelectric harvesting device is integrated into the wing of a UAV and provides energy harvesting, energy storage, and load bearing capability. The brittle piezoceramic layer of the harvester is a critical member in load bearing applications; therefore, it is the goal of this research to investigate the bending strength of various common piezoceramic materials. Three-point bend tests are carried out on several piezoelectric ceramics including monolithic piezoceramics PZT-5A and PZT-5H, single crystal piezoelectric PMN-PZT, and commercially packaged QuickPack devices. Bending strength results are reported and can be used as a design tool in the development of piezoelectric vibration energy harvesting systems in which the active device is subjected to bending loads.
NASA Astrophysics Data System (ADS)
Ansari, R.; Ajori, S.; Ameri, A.
2015-10-01
The properties and behavior of carbon nanotubes (CNTs) in aqueous environment due to their considerable potential applications in nanobiotechnology and designing nanobiosensors have attracted the attention of researchers. In this study, molecular dynamics simulations are carried out to investigate the vibrational characteristics of single- and double-walled CNTs containing ice nanotubes (a new phase of ice) in vacuum and aqueous environments. The results demonstrate that formation of ice nanotubes inside the CNTs reduces the natural frequency of pure CNTs. Moreover, it is demonstrated that increasing the number of walls considerably reduces the sensitivity of frequency to the presence of ice nanotube inside CNT. Additionally, it is shown that increasing the length decreases the effect of ice nanotube on reducing the frequency. The calculation of natural frequency of CNTs in aqueous media demonstrates that the interaction of CNTs with water molecules considerably reduces the natural frequency up to 50 %. Finally, it is demonstrated that in the case of CNTs with one free end in aqueous environment, the CNT does not vibrate in its first mode, and its frequency is between the frequencies of first and second modes of vibration.
Optimal Base Station Density of Dense Network: From the Viewpoint of Interference and Load.
Feng, Jianyuan; Feng, Zhiyong
2017-09-11
Network densification is attracting increasing attention recently due to its ability to improve network capacity by spatial reuse and relieve congestion by offloading. However, excessive densification and aggressive offloading can also cause the degradation of network performance due to problems of interference and load. In this paper, with consideration of load issues, we study the optimal base station density that maximizes the throughput of the network. The expected link rate and the utilization ratio of the contention-based channel are derived as the functions of base station density using the Poisson Point Process (PPP) and Markov Chain. They reveal the rules of deployment. Based on these results, we obtain the throughput of the network and indicate the optimal deployment density under different network conditions. Extensive simulations are conducted to validate our analysis and show the substantial performance gain obtained by the proposed deployment scheme. These results can provide guidance for the network densification.
NASA Astrophysics Data System (ADS)
Chen, Feier; Tian, Kang; Ding, Xiaoxu; Miao, Yuqi; Lu, Chunxia
2016-11-01
Analysis of freight rate volatility characteristics attracts more attention after year 2008 due to the effect of credit crunch and slowdown in marine transportation. The multifractal detrended fluctuation analysis technique is employed to analyze the time series of Baltic Dry Bulk Freight Rate Index and the market trend of two bulk ship sizes, namely Capesize and Panamax for the period: March 1st 1999-February 26th 2015. In this paper, the degree of the multifractality with different fluctuation sizes is calculated. Besides, multifractal detrending moving average (MF-DMA) counting technique has been developed to quantify the components of multifractal spectrum with the finite-size effect taken into consideration. Numerical results show that both Capesize and Panamax freight rate index time series are of multifractal nature. The origin of multifractality for the bulk freight rate market series is found mostly due to nonlinear correlation.
Tomoda, Akemi
2011-09-01
In recent years, the topic of child abuse as an issue facing Japanese society has gained considerable attention with regard to the field of medicine and education and also in scenarios that relate to child care. The definition of child abuse includes abusing children verbally or psychologically, and is not limited to abusing children physically such as beating, sexual abuse, or neglect. Recent studies have revealed that emotional trauma during childhood development could be much more difficult to treat than physical abuse. Severe abuse during childhood can cause abnormal brain development and have a negative impact later in life. In this review, I will introduce the mechanisms of brain damage due to child abuse with consideration of how and when child abuse can have an impact on the victims' brains. The information presented is based on a collaborative study with the Psychiatry Department at Harvard University on the relationship between brain functions and the human mind.
Sex-related responses after traumatic brain injury: Considerations for preclinical modeling.
Späni, Claudia B; Braun, David J; Van Eldik, Linda J
2018-05-18
Traumatic brain injury (TBI) has historically been viewed as a primarily male problem, since men are more likely to experience a TBI because of more frequent participation in activities that increase risk of head injuries. This male bias is also reflected in preclinical research where mostly male animals have been used in basic and translational science. However, with an aging population in which TBI incidence is increasingly sex-independent due to falls, and increasing female participation in high-risk activities, the attention to potential sex differences in TBI responses and outcomes will become more important. These considerations are especially relevant in designing preclinical animal models of TBI that are more predictive of human responses and outcomes. This review characterizes sex differences following TBI with a special emphasis on the contribution of the female sex hormones, progesterone and estrogen, to these differences. This information is potentially important in developing and customizing TBI treatments. Copyright © 2018 Elsevier Inc. All rights reserved.
Attention Deficit Disorder: Diagnosis, Etiology and Treatment.
ERIC Educational Resources Information Center
Barabasz, Marianne; Barabasz, Arreed
1996-01-01
Provides most recent information on attention deficit disorder including: (1) diagnostic considerations according to the latest behavioral criteria and breakthroughs using neurometric EEG assessment; (2) prevalence; (3) etiologies; (4) neurological basis; and (5) treatments. Evaluates alternatives to medication, behavior modification, cognitive…
Effects of noise and electromagnetic fields on reproductive outcomes.
Meyer, R E; Aldrich, T E; Easterly, C E
1989-01-01
Much public health research has been directed to studies of cancer risks due to chemical agents. Recently, increasing attention has been given to adverse reproductive outcomes as another, shorter-term biologic indicator of public health impact. Further, several low-level ubiquitous physical agents have been implicated recently as possibly affecting human health. These physical factors (noise and electromagnetic fields) represent difficult topics for research with epidemiologic study methods. This paper provides a brief review of the published data related to the risk of adverse reproductive outcomes and exposure to noise or electromagnetic fields. The discussion includes ideas for possible biologic mechanisms, considerations for exposure assessment, and suggestions for epidemiologic research. PMID:2667980
The applications of carbon nanomaterials in fiber-shaped energy storage devices
NASA Astrophysics Data System (ADS)
Wu, Jingxia; Hong, Yang; Wang, Bingjie
2018-01-01
As a promising candidate for future demand, fiber-shaped electrochemical energy storage devices, such as supercapacitors and lithium-ion batteries have obtained considerable attention from academy to industry. Carbon nanomaterials, such as carbon nanotube and graphene, have been widely investigated as electrode materials due to their merits of light weight, flexibility and high capacitance. In this review, recent progress of carbon nanomaterials in flexible fiber-shaped energy storage devices has been summarized in accordance with the development of fibrous electrodes, including the diversified electrode preparation, functional and intelligent device structure, and large-scale production of fibrous electrodes or devices. Project supported by the National Natural Science Foundation of China (Nos. 21634003, 21604012).
Optical systems engineering - A tutorial
NASA Technical Reports Server (NTRS)
Wyman, C. L.
1979-01-01
The paper examines the use of the systems engineering approach in the design of optical systems, noting that the use of such an approach which involves an integrated interdisciplinary approach to the development of systems is most appropriate for optics. It is shown that the high precision character of optics leads to complex and subtle effects on optical system performance, resulting from structural, thermal dynamical, control system, and manufacturing and assembly considerations. Attention is given to communication problems that often occur among users and optical engineers due to the unique factors of optical systems. It is concluded that it is essential that the optics community provide leadership to resolve communication problems and fully formalize the field of optical systems engineering.
Visible Light Photocatalysis via CdS/ TiO 2 Nanocomposite Materials
Srinivasan, Sesha S.; Wade, Jeremy; Stefanakos, Elias K.
2006-01-01
Nmore » anostructured colloidal semiconductors with heterogeneous photocatalytic behavior have drawn considerable attention over the past few years. This is due to their large surface area, high redox potential of the photogenerated charge carriers, and selective reduction/oxidation of different classes of organic compounds. In the present paper, we have carried out a systematic synthesis of nanostructured CdS- TiO 2 via reverse micelle process. The structural and microstructural characterizations of the as-prepared CdS- TiO 2 nanocomposites are determined using XRD and SEM-EDS techniques. The visible light assisted photocatalytic performance is monitored by means of degradation of phenol in water suspension.« less
NASA Astrophysics Data System (ADS)
Azizi, Zahra Sadat; Tehranchi, Mohammad Mehdi; Vakili, Seyed Hamed; Pourmahdian, Saeed
2018-05-01
Engineering approach towards combined photonic band gap properties and magnetic/polymer composite particles, attract considerable attention of researchers due to their unique properties. In this research, two different magnetic particles were prepared by nearly monodisperse polystyrene spheres as bead with two concentrations of Fe3O4 nanoparticles to prepare magnetic photonic crystals (MPCs). The crystal surfaces and particles morphology were investigated employing scanning electron microscopy and transmission electron microscopy. The volume fraction of magnetic material embedded into colloidal spheres and their morphology was found to be a key parameter in the optical and magneto-optical properties of transparent MPC.
A Brief Review on Multivalent Intercalation Batteries with Aqueous Electrolytes.
Guduru, Ramesh K; Icaza, Juan C
2016-02-26
Rapidly growing global demand for high energy density rechargeable batteries has driven the research toward developing new chemistries and battery systems beyond Li-ion batteries. Due to the advantages of delivering more than one electron and giving more charge capacity, the multivalent systems have gained considerable attention. At the same time, affordability, ease of fabrication and safety aspects have also directed researchers to focus on aqueous electrolyte based multivalent intercalation batteries. There have been a decent number of publications disclosing capabilities and challenges of several multivalent battery systems in aqueous electrolytes, and while considering an increasing interest in this area, here, we present a brief overview of their recent progress, including electrode chemistries, functionalities and challenges.
Hydrodynamic Electron Flow and Hall Viscosity
NASA Astrophysics Data System (ADS)
Scaffidi, Thomas; Nandi, Nabhanila; Schmidt, Burkhard; Mackenzie, Andrew P.; Moore, Joel E.
2017-06-01
In metallic samples of small enough size and sufficiently strong momentum-conserving scattering, the viscosity of the electron gas can become the dominant process governing transport. In this regime, momentum is a long-lived quantity whose evolution is described by an emergent hydrodynamical theory. Furthermore, breaking time-reversal symmetry leads to the appearance of an odd component to the viscosity called the Hall viscosity, which has attracted considerable attention recently due to its quantized nature in gapped systems but still eludes experimental confirmation. Based on microscopic calculations, we discuss how to measure the effects of both the even and odd components of the viscosity using hydrodynamic electronic transport in mesoscopic samples under applied magnetic fields.
Hydrodynamic Electron Flow and Hall Viscosity.
Scaffidi, Thomas; Nandi, Nabhanila; Schmidt, Burkhard; Mackenzie, Andrew P; Moore, Joel E
2017-06-02
In metallic samples of small enough size and sufficiently strong momentum-conserving scattering, the viscosity of the electron gas can become the dominant process governing transport. In this regime, momentum is a long-lived quantity whose evolution is described by an emergent hydrodynamical theory. Furthermore, breaking time-reversal symmetry leads to the appearance of an odd component to the viscosity called the Hall viscosity, which has attracted considerable attention recently due to its quantized nature in gapped systems but still eludes experimental confirmation. Based on microscopic calculations, we discuss how to measure the effects of both the even and odd components of the viscosity using hydrodynamic electronic transport in mesoscopic samples under applied magnetic fields.
Wireless powering of e -swimmers
NASA Astrophysics Data System (ADS)
Roche, Jérome; Carrara, Serena; Sanchez, Julien; Lannelongue, Jérémy; Loget, Gabriel; Bouffier, Laurent; Fischer, Peer; Kuhn, Alexander
2014-10-01
Miniaturized structures that can move in a controlled way in solution and integrate various functionalities are attracting considerable attention due to the potential applications in fields ranging from autonomous micromotors to roving sensors. Here we introduce a concept which allows, depending on their specific design, the controlled directional motion of objects in water, combined with electronic functionalities such as the emission of light, sensing, signal conversion, treatment and transmission. The approach is based on electric field-induced polarization, which triggers different chemical reactions at the surface of the object and thereby its propulsion. This results in a localized electric current that can power in a wireless way electronic devices in water, leading to a new class of electronic swimmers (e-swimmers).
Strategic Design for Delivery with Linked Transportation Assets : Trucks and Drones
DOT National Transportation Integrated Search
2018-01-01
Home delivery by drones as an alternative or complement to traditional delivery by trucks is attracting considerable attention from major retailers and services, as well as startups. While drone delivery may offer considerable economic savings, the f...
NASA Astrophysics Data System (ADS)
Aleksandrov, V. A.; Vladimirov, V. V.; Dmitriev, R. D.; Osipov, S. O.
This book takes into consideration domestic and foreign developments related to launch vehicles. General information concerning launch vehicle systems is presented, taking into account details of rocket structure, basic design considerations, and a number of specific Soviet and American launch vehicles. The basic theory of reaction propulsion is discussed, giving attention to physical foundations, the various types of forces acting on a rocket in flight, basic parameters characterizing rocket motion, the effectiveness of various approaches to obtain the desired velocity, and rocket propellants. Basic questions concerning the classification of launch vehicles are considered along with construction and design considerations, aspects of vehicle control, reliability, construction technology, and details of structural design. Attention is also given to details of rocket motor design, the basic systems of the carrier rocket, and questions of carrier rocket development.
Performance data for a terrestrial solar photovoltaic/water electrolysis experiment
NASA Technical Reports Server (NTRS)
Costogue, E. N.; Yasui, R. K.
1977-01-01
A description is presented of the equipment used in the experiment, taking into account the surplus solar panel from the Mariner 4 spacecraft which was used as a solar array source and an electrolytic hydrogen generator. Attention is also given to operational considerations and performance data, system considerations and aspects of optimization, and large-scale hydrogen production considerations.
ERIC Educational Resources Information Center
Toumasis, Charalampos
2004-01-01
Emphasis on problem solving and mathematical modeling has gained considerable attention in the last few years. Connecting mathematics to other subjects and to the real world outside the classroom has received increased attention in mathematics programs. This article describes an application of simple differential equations in the field of…
Validity in Qualitative Research: Application of Safeguards
ERIC Educational Resources Information Center
Daytner, Katrina M.
2006-01-01
The construct of validity has received considerable attention in qualitative methods literature (Denzin, 1989; Erickson, 1986; Geertz, 1973; Goetz & LeCompte, 1984; Howe & Eisenhart, 1990; Maxwell, 1992; Smith & Glass, 1987). Much of the attention has been focused upon the issue of whether qualitative results and interpretations accurately reflect…
Threat-Related Attentional Bias in Anxious Youth: A Review
ERIC Educational Resources Information Center
Puliafico, Anthony C.; Kendall, Philip C.
2006-01-01
The research literature suggests that children and adolescents suffering from anxiety disorders experience cognitive distortions that magnify their perceived level of threat in the environment. Of these distortions, an attentional bias toward threat-related information has received the most theoretical and empirical consideration. A large volume…
Common office procedures and analgesia considerations.
Baxter, Amy
2013-10-01
This article reviews common office procedures and analgesia considerations for pediatric outpatients. Layer times of onset of analgesics to coincide with procedures. Pediatric procedural distress is multimodal. Always address parent and child fear and attention, along with pain. Copyright © 2013 Elsevier Inc. All rights reserved.
Strategy for the Eighties: High Technology Industrial Development.
ERIC Educational Resources Information Center
Kansas State Dept. of Economic Development, Topeka.
The need for high technology development in Kansas is assessed, with attention to community considerations and the roles of universities and state government in fostering technology development and community considerations. After defining a high technology industry, technologically innovative industries are identified, and influences on the…
Background Models that allow for design considerations of green infrastructure (GI) practices to control stormwater runoff and associated contaminants have received considerable attention in recent years. While popular, generally, the GI models are relatively simplistic. However,...
[Providing regular relief; considerations for palliative care in the Netherlands].
Crul, B J; van Weel, C
2001-10-20
Over the last few decades the attention devoted to the palliative aspects of medicine, particularly those in hospital care, has declined due to the emphasis on medical technology. In Anglo-Saxon countries a review of this development resulted in structured palliative care that benefited terminally ill patients with a progressive fatal disease, especially cancer patients. Due to increasing national and international criticism of both the practice of euthanasia (assumed to be too liberal) and the lack of attention devoted to structured palliative care in the Netherlands, the Dutch government decided to improve the structure of palliative care. The government's viewpoint is based on the assumption that good palliative care that includes adequate pain control benefits patient care and might eventually lead to fewer requests for euthanasia. The improvements to palliative care should be realised by means of improvements in the structure, training and knowledge. Six academic medical clusters have been designated as Centres for the Development of Palliative Care (Dutch acronym: COPZ) for a 5-year period. Each COPZ must develop the various aspects needed to improve palliative care within the region it serves and ensure that its activities are carefully coordinated with those in the other centres. Research will focus on measuring the efficacy of palliative care as well as ethical and epidemiological aspects. A government committee will assess the appropriateness of the activities undertaken by each of the centres.
Risko, Evan F; Kingstone, Alan
2017-06-01
Understanding the basic mechanisms underlying attentional function using naturalistic stimuli, tasks, and/or settings is the focus of everyday attention research. Interest in everyday approaches to attention research has increased recently-arguably riding a more general wave of support for such considerations in experimental psychology. This special issue of the Canadian Journal of Experimental Psychology attempts to capture the emerging enthusiasm for studying everyday attention by bringing together work from a wide array of attentional domains (e.g., visual attention, dual tasking, search, mind wandering, social attention) that are representative of this general approach. The 14 contributions to the special issue highlight the breadth of topics addressed in this research, the methodological creativity required to carry it out, and the promise of everyday attention for understanding the basic mechanisms underlying attentional function. This introduction will summarise the everyday attention approach as represented in the contributions to the special issue. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Institutional Educational Technology Policy and Strategy Documents: An Inequality Gaze
ERIC Educational Resources Information Center
Czerniewicz, Laura; Rother, Kyle
2018-01-01
Issues of inequality in higher education have received considerable attention in recent decades, but the intersection of inequality and educational technology at an institutional level has received little attention. This study aims to provide a perspective on institutional educational technology policy informed by current understandings of…
Task Engagement, Cerebral Blood Flow Velocity, and Diagnostic Monitoring for Sustained Attention
ERIC Educational Resources Information Center
Matthews, Gerald; Warm, Joel S.; Reinerman-Jones, Lauren E.; Langheim, Lisa K.; Washburn, David A.; Tripp, Lloyd
2010-01-01
Loss of vigilance may lead to impaired performance in various applied settings including military operations, transportation, and industrial inspection. Individuals differ considerably in sustained attention, but individual differences in vigilance have proven to be hard to predict. The dependence of vigilance on workload factors is consistent…
Quantifying ADHD Classroom Inattentiveness, Its Moderators, and Variability: A Meta-Analytic Review
ERIC Educational Resources Information Center
Kofler, Michael J.; Rapport, Mark D.; Alderson, R. Matt
2008-01-01
Background: Most classroom observation studies have documented significant deficiencies in the classroom attention of children with attention-deficit/hyperactivity disorder (ADHD) compared to their typically developing peers. The magnitude of these differences, however, varies considerably and may be influenced by contextual, sampling, diagnostic,…
Continuous Performance Tasks: Not Just about Sustaining Attention
ERIC Educational Resources Information Center
Roebuck, Hettie; Freigang, Claudia; Barry, Johanna G.
2016-01-01
Purpose: Continuous performance tasks (CPTs) are used to measure individual differences in sustained attention. Many different stimuli have been used as response targets without consideration of their impact on task performance. Here, we compared CPT performance in typically developing adults and children to assess the role of stimulus processing…
Accommodating Faculty Members Who Have Disabilities. Report
ERIC Educational Resources Information Center
American Association of University Professors, 2012
2012-01-01
In recent years the rights and responsibilities of students who have disabilities have received considerable attention. Professors routinely accommodate students with a front-row seat in class or extended time on an examination. Faculty members who have disabilities have received far less attention. This report from a subcommittee of Committee A…
ERIC Educational Resources Information Center
Olaniran, Bolanle A.
2006-01-01
Purpose: The increased pressure to incorporate communication technologies into learning environments has intensified the attention given to the role of computer-mediated communication (CMC) in academic settings. However, the issue of how and why these technologies, especially synchronous CMC applications, has been given less attention in…
Goodman, David W; Mitchell, Sara; Rhodewalt, Lauren; Surman, Craig B H
2016-01-01
Although previously considered a disorder of childhood, studies in the last decade have demonstrated that attention-deficit hyperactivity disorder (ADHD) continues to impair function into adulthood and responds to pharmacotherapy. Due to age-specific changes in roles and challenges, it is possible that presentation and response to intervention may differ between older and younger adults. A literature search for papers that identified older adults with ADHD, including papers describing its epidemiology, manifestation, and treatment, was the basis for this paper. There is a paucity of data on ADHD in older adults; however, small observational studies have characterized the presence, impact, and treatment of ADHD in adults over the age of 50 years, and larger epidemiologic studies have demonstrated that ADHD symptoms exist in older adulthood. Optimal criteria for diagnosis of ADHD and methods of treating ADHD in older individuals have not been systematically explored. In light of the limited data, this review discusses considerations for differential diagnosis and safe pharmacotherapy of ADHD in older adults.
Response Inhibition and Interference Control in Obsessive–Compulsive Spectrum Disorders
van Velzen, Laura S.; Vriend, Chris; de Wit, Stella J.; van den Heuvel, Odile A.
2014-01-01
Over the past 20 years, motor response inhibition and interference control have received considerable scientific effort and attention, due to their important role in behavior and the development of neuropsychiatric disorders. Results of neuroimaging studies indicate that motor response inhibition and interference control are dependent on cortical–striatal–thalamic–cortical (CSTC) circuits. Structural and functional abnormalities within the CSTC circuits have been reported for many neuropsychiatric disorders, including obsessive–compulsive disorder (OCD) and related disorders, such as attention-deficit hyperactivity disorder, Tourette’s syndrome, and trichotillomania. These disorders also share impairments in motor response inhibition and interference control, which may underlie some of their behavioral and cognitive symptoms. Results of task-related neuroimaging studies on inhibitory functions in these disorders show that impaired task performance is related to altered recruitment of the CSTC circuits. Previous research has shown that inhibitory performance is dependent upon dopamine, noradrenaline, and serotonin signaling, neurotransmitters that have been implicated in the pathophysiology of these disorders. In this narrative review, we discuss the common and disorder-specific pathophysiological mechanisms of inhibition-related dysfunction in OCD and related disorders. PMID:24966828
Interfacial contributions in lignocellulosic firber-reinforced polyurethane composites
Timothy G. Rials; Michael P. Wolcott; John M. Nassar
2001-01-01
Whereas lignocellulosic fibers have received considerable attention as a reinforcing agent in thermoplastic composites, their applicability to reactive polymer systems remains of considerable interest. The hydroxyl-rich nature of natural lignocellulosic fibers suggests that they are particularly useful in thermsetting systems such as polyurethanes. To further this...
Mattejat, F; Wüthrich, C; Remschmidt, H
2000-03-01
Children of psychiatrically ill parents represent a risk group that has received growing attention during the last years. The risk for this group to develop a psychiatric illness is markedly increased due to genetic and psychosocial factors. The development of effective preventive concepts requires a thorough knowledge of the psychosocial factors. In this paper, deficits and problems of research in psychosocial transmission mechanism are discussed taking the example of children of depressive parents. Conclusions from this exemplary considerations may serve as guidelines for future research. The authors suggest that the focus be rather placed on coping strategies and developmental psychopathology. Further, research criteria are formulated that refer to theoretical models as well as to study design.
Distributed Efficient Similarity Search Mechanism in Wireless Sensor Networks
Ahmed, Khandakar; Gregory, Mark A.
2015-01-01
The Wireless Sensor Network similarity search problem has received considerable research attention due to sensor hardware imprecision and environmental parameter variations. Most of the state-of-the-art distributed data centric storage (DCS) schemes lack optimization for similarity queries of events. In this paper, a DCS scheme with metric based similarity searching (DCSMSS) is proposed. DCSMSS takes motivation from vector distance index, called iDistance, in order to transform the issue of similarity searching into the problem of an interval search in one dimension. In addition, a sector based distance routing algorithm is used to efficiently route messages. Extensive simulation results reveal that DCSMSS is highly efficient and significantly outperforms previous approaches in processing similarity search queries. PMID:25751081
Uncoupling Protein 2 and Metabolic Diseases
Sreedhar, Annapoorna; Zhao, Yunfeng
2017-01-01
Mitochondria are fascinating organelles involved in various cellular-metabolic activities that are integral for mammalian development. Although they perform diverse, yet interconnected functions, mitochondria are remarkably regulated by complex signaling networks. Therefore, it is not surprising that mitochondrial dysfunction is involved in plethora of diseases, including neurodegenerative and metabolic disorders. One of the many factors that lead to mitochondrial-associated metabolic diseases is the uncoupling protein-2, a family of mitochondrial anion proteins present in the inner mitochondrial membrane. Since their discovery, uncoupling proteins have attracted considerable attention due to their involvement in mitochondrial-mediated oxidative stress and energy metabolism. This review attempts to provide a summary of recent developments in the field of uncoupling protein 2 relating to mitochondrial associated metabolic diseases. PMID:28351676
Theoretical study on physicochemical properties of curcumin
NASA Astrophysics Data System (ADS)
Shen, Liang; Ji, Hong-Fang
2007-07-01
Curcumin is a yellow-orange pigment, which has attracted considerable attention due to its wide spectrum of biological and pharmacological activities. In spite of much effort devoted on curcumin, there still exist some open questions concerning its fundamental physicochemical properties. The present study suggests that the DFT and TD-DFT calculations are useful to answer these questions. Firstly, the thermodynamic as well as spectral parameters support that curcumin exists predominantly in enol form in solution. Secondly, the calculated absorption spectra of curcumin anions provides direct evidence that the lowest p Ka of curcumin corresponds to the dissociation of enolic proton, which not only reconciles the controversy on this topic, but also has important implications on the proton-transfer/dissociation-associated radical-scavenging mechanisms of curcumin.
Laser diagnostics for combustion temperature and species
DOE Office of Scientific and Technical Information (OSTI.GOV)
Eckbreth, A.C.
1987-01-01
Laser approaches to combustion diagnostics are of considerable interest due to their remote, nonintrusive and in-situ character, unlimited temperature capability and potential for simultaneous temporal and spatial resolution, This book aims to make these powerful and important new tools in combustion research understandable. The focus of this text is on spectroscopically-based, spatially-precise laser techniques for temperature and chemical composition measurements in reacting and nonreacting flows. After introductory chapters providing a fundamental theoretical and experimental background, attention is directed to diagnostics based upon spontaneous Raman and Rayleigh scattering, coherent anti-Stokes Raman spectroscopy (CARS) and laser-induced fluorescence (LIFS). The book concludes withmore » a treatment of techniques which permit spatially-resolved measurements over an entire two-dimensional field simultaneously.« less
Evolution of In-Situ Generated Reinforcement Precipitates in Metal Matrix Composites
NASA Technical Reports Server (NTRS)
Sen, S.; Kar, S. K.; Catalina, A. V.; Stefanescu, D. M.; Dhindaw, B. K.
2004-01-01
Due to certain inherent advantages, in-situ production of Metal Matrix Composites (MMCs) have received considerable attention in the recent past. ln-situ techniques typically involve a chemical reaction that results in precipitation of a ceramic reinforcement phase. The size and spatial distribution of these precipitates ultimately determine the mechanical properties of these MMCs. In this paper we will investigate the validity of using classical growth laws and analytical expressions to describe the interaction between a precipitate and a solid-liquid interface (SLI) to predict the size and spatial evolution of the in-situ generated precipitates. Measurements made on size and distribution of Tic precipitates in a Ni&I matrix will be presented to test the validity of such an approach.
Fungal Phytotoxins in Sustainable Weed Management.
Vurro, Maurizio; Boari, Angela; Casella, Francesca; Zonno, Maria Chiara
2018-01-01
Fungal phytotoxins are natural secondary metabolites produced by plant pathogenic fungi during host-pathogen interactions. They have received considerable particular attention for elucidating disease etiology, and consequently to design strategies for disease control. Due to wide differences in their chemical structures, these toxic metabolites have different ecological and environmental roles and mechanisms of action. This review aims at summarizing the studies on the possible use of these metabolites as tools in biological and integrated weed management, e.g. as: novel and environmentally friendly herbicides; lead for novel compounds; sources of novel mechanisms of action. Moreover, the limiting factors for utilizing those metabolites in practice will also be briefly discussed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
A Brief Review on Multivalent Intercalation Batteries with Aqueous Electrolytes
Guduru, Ramesh K.; Icaza, Juan C.
2016-01-01
Rapidly growing global demand for high energy density rechargeable batteries has driven the research toward developing new chemistries and battery systems beyond Li-ion batteries. Due to the advantages of delivering more than one electron and giving more charge capacity, the multivalent systems have gained considerable attention. At the same time, affordability, ease of fabrication and safety aspects have also directed researchers to focus on aqueous electrolyte based multivalent intercalation batteries. There have been a decent number of publications disclosing capabilities and challenges of several multivalent battery systems in aqueous electrolytes, and while considering an increasing interest in this area, here, we present a brief overview of their recent progress, including electrode chemistries, functionalities and challenges. PMID:28344298
Estimation of TOA based MUSIC algorithm and cross correlation algorithm of appropriate interval
NASA Astrophysics Data System (ADS)
Lin, Wei; Liu, Jun; Zhou, Yineng; Huang, Jiyan
2017-03-01
Localization of mobile station (MS) has now gained considerable attention due to its wide applications in military, environmental, health and commercial systems. Phrase angle and encode data of MSK system model are two critical parameters in time-of-arrival (TOA) localization technique; nevertheless, precise value of phrase angle and encode data are not easy to achieved in general. In order to meet the actual situation, we should consider the condition that phase angle and encode data is unknown. In this paper, a novel TOA localization method, which combine MUSIC algorithm and cross correlation algorithm in an appropriate interval, is proposed. Simulations show that the proposed method has better performance than music algorithm and cross correlation algorithm of the whole interval.
Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects.
Mechoulam, Raphael; Hanus, Lumír
2002-12-31
Over the last few years considerable attention has focused on cannabidiol (CBD), a major non-psychotropic constituent of Cannabis. In Part I of this review we present a condensed survey of the chemistry of CBD; in Part II, to be published later, we shall discuss the anti-convulsive, anti-anxiety, anti-psychotic, anti-nausea and anti-rheumatoid arthritic properties of CBD. CBD does not bind to the known cannabinoid receptors and its mechanism of action is yet unknown. In Part II we shall also present evidence that it is conceivable that, in part at least, its effects are due to its recently discovered inhibition of anandamide uptake and hydrolysis and to its anti-oxidative effect.
(Tl, Sb) and (Tl, Bi) binary surface reconstructions on Ge(111) substrate
NASA Astrophysics Data System (ADS)
Gruznev, D. V.; Bondarenko, L. V.; Tupchaya, A. Y.; Yakovlev, A. A.; Mihalyuk, A. N.; Zotov, A. V.; Saranin, A. A.
2018-03-01
2D compounds made of Group-III and Group-V elements on the surface of silicon and germanium attract considerable attention due to prospects of creating III-V binary monolayers, which are predicted to hold advanced physical properties. In the present work, we have investigated two such systems, (Tl, Sb)/Ge(111) and (Tl, Bi)/Ge(111) using scanning tunneling microscopy, low energy electron diffraction observations and density-functional-theory calculations. In addition to the previously reported surface structures of 2D (Tl, Sb) and (Tl, Bi) compounds on Si(111), we found new ones, namely, √{ 7} × √{ 7} and 3 × 3. Formation processes and plausible models of their atomic arrangements are discussed.
Shieh, Gwowen
2010-05-28
Due to its extensive applicability and computational ease, moderated multiple regression (MMR) has been widely employed to analyze interaction effects between 2 continuous predictor variables. Accordingly, considerable attention has been drawn toward the supposed multicollinearity problem between predictor variables and their cross-product term. This article attempts to clarify the misconception of multicollinearity in MMR studies. The counterintuitive yet beneficial effects of multicollinearity on the ability to detect moderator relationships are explored. Comprehensive treatments and numerical investigations are presented for the simplest interaction model and more complex three-predictor setting. The results provide critical insight that both helps avoid misleading interpretations and yields better understanding for the impact of intercorrelation among predictor variables in MMR analyses.
Plasticity models of material variability based on uncertainty quantification techniques
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jones, Reese E.; Rizzi, Francesco; Boyce, Brad
The advent of fabrication techniques like additive manufacturing has focused attention on the considerable variability of material response due to defects and other micro-structural aspects. This variability motivates the development of an enhanced design methodology that incorporates inherent material variability to provide robust predictions of performance. In this work, we develop plasticity models capable of representing the distribution of mechanical responses observed in experiments using traditional plasticity models of the mean response and recently developed uncertainty quantification (UQ) techniques. Lastly, we demonstrate that the new method provides predictive realizations that are superior to more traditional ones, and how these UQmore » techniques can be used in model selection and assessing the quality of calibrated physical parameters.« less
Common procedures and strategies for anaesthesia in interventional radiology.
Landrigan-Ossar, Mary
2015-08-01
This review describes the range of cases now available in the interventional radiology suite and summarizes suggestions for their anaesthetic and perioperative management. The type and complexity of interventional radiology cases being performed increases from year to year. Anaesthesiologists' presence in interventional radiology is increasing in turn, due to increasingly ill patients and intricate procedures requiring more than local anaesthesia for well tolerated completion. The literature available describing this is largely written by radiologists, with little attention paid to anaesthetic considerations. Cases in interventional radiology are complex in terms of the logistics of working in an unfamiliar area, frequency of patient comorbidity and unfamiliar procedures. Ensuring familiarity with the variety of interventional radiology procedures and their periprocedure requirements can increase anaesthesiologists' comfort in interventional radiology.
On the importance of listening comprehension
Hogan, Tiffany P.; Adlof, Suzanne M.; Alonzo, Crystle
2015-01-01
The simple view of reading highlights the importance of two primary components which account for individual differences in reading comprehension across development: word recognition (i.e., decoding) and listening comprehension. While assessments and interventions for decoding have been the focus of pedagogy in the past several decades, the importance of listening comprehension has received less attention. This paper reviews evidence showing that listening comprehension becomes the dominating influence on reading comprehension starting even in the elementary grades. It also highlights a growing number of children who fail to develop adequate reading comprehension skills, primarily due to deficient listening comprehension skills: poor comprehenders. Finally it discusses key language influences on listening comprehension for consideration during assessment and treatment of reading disabilities. PMID:24833426
On the importance of listening comprehension.
Hogan, Tiffany P; Adlof, Suzanne M; Alonzo, Crystle N
2014-06-01
The simple view of reading highlights the importance of two primary components which account for individual differences in reading comprehension across development: word recognition (i.e., decoding) and listening comprehension. While assessments and interventions for decoding have been the focus of pedagogy in the past several decades, the importance of listening comprehension has received less attention. This paper reviews evidence showing that listening comprehension becomes the dominating influence on reading comprehension starting even in the elementary grades. It also highlights a growing number of children who fail to develop adequate reading comprehension skills, primarily due to deficient listening comprehension skills (i.e., poor comprehenders). Finally we discuss key language influences on listening comprehension for consideration during assessment and treatment of reading disabilities.
2015-11-01
addressed in Study 1, was to measure the associations between state and trait anger and biases in anger-related attention and interpretation. This aim was...presented in the recent MOMRP conference, and physiological SCR data are in the last stages of analyses. 15. SUBJECT TERMS anger, aggression, attention ...threat conditions, ranging from safety to acute danger, considerable plasticity in threat-related attention and threat interpretation is required
Toward a New Philosophical Anthropology of Education: Fuller Considerations of Social Constructivism
ERIC Educational Resources Information Center
Fleury, Stephen; Garrison, Jim
2014-01-01
Philosophical anthropology is philosophical inquiry into human nature that seeks to answer the fundamental question of what generally characterizes human beings and differentiates them from other creatures and things. Political theories considerably influence educational theories. We call attention to the fact that the three main political…
A Qualitative Examination of Ethical and Legal Considerations Regarding Dating Violence
ERIC Educational Resources Information Center
Sikes, April; Walley, Cynthia; Hays, Danica G.
2012-01-01
Despite the increased attention to dating violence among adolescents and young adults, limited information is available on ethical and legal considerations specific to this population. Therefore, this qualitative study explores 21 trainees' and practitioners' conceptualization of ethical and legal issues pertaining to adolescent dating violence.…
Interfacial contributions in lignocellulosic fiber-reinforced polyurethane composites
Timothy G. Rials; Michael P. Wolcott; John M. Nassar
2001-01-01
Whereas lignocellulosic fibers have received considerable attention as a rein- forcing agent in thermoplastic composites, their applicability to reactive polymer systems remains of considerable interest. The hydroxyl-rich nature of natural lignocellulosic fibers suggests that they are particularly useful in thermosetting systems such as polyurethanes. To further this...
Ethical Considerations in Filing Personal Bankruptcy: A Hypothetical Case Study
ERIC Educational Resources Information Center
Landry, Robert J., III
2012-01-01
A great deal of research by legal studies scholars pertains to employment law, international law, and corporate governance, as well as other fields including ethics and international law. The fields typically addressed are very important and rightfully receive considerable attention in the scholarship and textbooks. However, bankruptcy as a…
ERIC Educational Resources Information Center
Trepal, Heather; Haberstroh, Shane; Duffey, Thelma; Evans, Marcheta
2007-01-01
As technology advances and the use of online counseling becomes more routine, attention must be paid to instruction regarding online counseling skills. The authors present considerations for teaching basic online counseling skills to master's-level counseling students. Recommendations are made for helping students to establish and maintain…
An exploration of jealousy in nursing: a Kleinian analysis.
Evans, Alicia M; Traynor, Michael; Glass, Nel
2014-06-01
It is well established that nursing practice produces considerable anxiety, and it can also give rise to envy and jealousy. While envy in nursing was identified in the literature more than 50 years ago, there remains a paucity of articles addressing either envy or jealousy for nurses. In a recent research study on current experiences of clinical practice, we analysed a fragment of nurses' speech via Klein's theory of jealousy. The results revealed that the nurses expressed jealousy at the privilege afforded to doctors. We argue that it is important to acknowledge jealousy in nursing practice because it has the potential for 'spoiling' effective care delivery and as such, can have detrimental ramifications in the health system. Also, jealousy may keep the nurse from fully focusing on their nursing practice in that it divides the nurse's attention and so limits the nurse's treatment of the patient. Nurses' jealousy of doctors is a taboo topic in nursing, and yet it warrants serious consideration due to the potential deleterious consequences that can arise when this dynamic is present. © 2013 John Wiley & Sons Ltd.
Neaţu, Ştefan; Maciá-Agulló, Juan Antonio; Garcia, Hermenegildo
2014-01-01
The reduction of carbon dioxide to useful chemicals has received a great deal of attention as an alternative to the depletion of fossil resources without altering the atmospheric CO2 balance. As the chemical reduction of CO2 is energetically uphill due to its remarkable thermodynamic stability, this process requires a significant transfer of energy. Achievements in the fields of photocatalysis during the last decade sparked increased interest in the possibility of using sunlight to reduce CO2. In this review we discuss some general features associated with the photocatalytic reduction of CO2 for the production of solar fuels, with considerations to be taken into account of the photocatalyst design, of the limitations arising from the lack of visible light response of titania, of the use of co-catalysts to overcome this shortcoming, together with several strategies that have been applied to enhance the photocatalytic efficiency of CO2 reduction. The aim is not to provide an exhaustive review of the area, but to present general aspects to be considered, and then to outline which are currently the most efficient photocatalytic systems. PMID:24670477
Qian Cutrone, Jingfang Jenny; Huang, Xiaohua Stella; Kozlowski, Edward S; Bao, Ye; Wang, Yingzi; Poronsky, Christopher S; Drexler, Dieter M; Tymiak, Adrienne A
2017-05-10
Synthetic macrocyclic peptides with natural and unnatural amino acids have gained considerable attention from a number of pharmaceutical/biopharmaceutical companies in recent years as a promising approach to drug discovery, particularly for targets involving protein-protein or protein-peptide interactions. Analytical scientists charged with characterizing these leads face multiple challenges including dealing with a class of complex molecules with the potential for multiple isomers and variable charge states and no established standards for acceptable analytical characterization of materials used in drug discovery. In addition, due to the lack of intermediate purification during solid phase peptide synthesis, the final products usually contain a complex profile of impurities. In this paper, practical analytical strategies and methodologies were developed to address these challenges, including a tiered approach to assessing the purity of macrocyclic peptides at different stages of drug discovery. Our results also showed that successful progression and characterization of a new drug discovery modality benefited from active analytical engagement, focusing on fit-for-purpose analyses and leveraging a broad palette of analytical technologies and resources. Copyright © 2017. Published by Elsevier B.V.
Neațu, Stefan; Maciá-Agulló, Juan Antonio; Garcia, Hermenegildo
2014-03-25
The reduction of carbon dioxide to useful chemicals has received a great deal of attention as an alternative to the depletion of fossil resources without altering the atmospheric CO2 balance. As the chemical reduction of CO2 is energetically uphill due to its remarkable thermodynamic stability, this process requires a significant transfer of energy. Achievements in the fields of photocatalysis during the last decade sparked increased interest in the possibility of using sunlight to reduce CO2. In this review we discuss some general features associated with the photocatalytic reduction of CO2 for the production of solar fuels, with considerations to be taken into account of the photocatalyst design, of the limitations arising from the lack of visible light response of titania, of the use of co-catalysts to overcome this shortcoming, together with several strategies that have been applied to enhance the photocatalytic efficiency of CO2 reduction. The aim is not to provide an exhaustive review of the area, but to present general aspects to be considered, and then to outline which are currently the most efficient photocatalytic systems.
Advances in the Applications of Polyhydroxyalkanoate Nanoparticles for Novel Drug Delivery System
Shrivastav, Anupama; Kim, Hae-Yeong; Kim, Young-Rok
2013-01-01
Drug delivery technology is emerging as an interdisciplinary science aimed at improving human health. The controlled delivery of pharmacologically active agents to the specific site of action at the therapeutically optimal rate and dose regimen has been a major goal in designing drug delivery systems. Over the past few decades, there has been considerable interest in developing biodegradable drug carriers as effective drug delivery systems. Polymeric materials from natural sources play an important role in controlled release of drug at a particular site. Polyhydroxyalkanoates, due to their origin from natural sources, are given attention as candidates for drug delivery materials. Biodegradable and biocompatible polyhydroxyalkanoates are linear polyesters produced by microorganisms under unbalanced growth conditions, which have emerged as potential polymers for use as biomedical materials for drug delivery due to their unique physiochemical and mechanical properties. This review summarizes many of the key findings in the applications of polyhydroxyalkanoates and polyhydroxyalkanoate nanoparticles for drug delivery system. PMID:23984383
NASA Astrophysics Data System (ADS)
Hruszkewycz, Stephan; Cha, Wonsuk; Ulvestad, Andrew; Fuoss, Paul; Heremans, F. Joseph; Harder, Ross; Andrich, Paolo; Anderson, Christopher; Awschalom, David
The nitrogen-vacancy center in diamond has attracted considerable attention for nanoscale sensing due to unique optical and spin properties. Many of these applications require diamond nanoparticles which contain large amounts of residual strain due to the detonation or milling process used in their fabrication. Here, we present experimental, in-situ observations of changes in morphology and internal strain state of commercial nanodiamonds during high-temperature annealing using Bragg coherent diffraction imaging to reconstruct a strain-sensitive 3D image of individual sub-micron-sized crystals. We find minimal structural changes to the nanodiamonds at temperatures less than 650 C, and that at higher temperatures up to 750 C, the diamond-structured volume fraction of nanocrystals tend to shrink. The degree of internal lattice distortions within nanodiamond particles also decreases during the anneal. Our findings potentially enable the design of efficient processing of commercial nanodiamonds into viable materials suitable for device design. We acknowledge support from U.S. DOE, Office of Science, BES, MSE.
NASA Astrophysics Data System (ADS)
Zhang, Chendong; Li, Ming-Yang; Tersoff, Jerry; Han, Yimo; Su, Yushan; Li, Lain-Jong; Muller, David A.; Shih, Chih-Kang
2018-02-01
Monolayer transition metal dichalcogenide heterojunctions, including vertical and lateral p-n junctions, have attracted considerable attention due to their potential applications in electronics and optoelectronics. Lattice-misfit strain in atomically abrupt lateral heterojunctions, such as WSe2-MoS2, offers a new band-engineering strategy for tailoring their electronic properties. However, this approach requires an understanding of the strain distribution and its effect on band alignment. Here, we study a WSe2-MoS2 lateral heterojunction using scanning tunnelling microscopy and image its moiré pattern to map the full two-dimensional strain tensor with high spatial resolution. Using scanning tunnelling spectroscopy, we measure both the strain and the band alignment of the WSe2-MoS2 lateral heterojunction. We find that the misfit strain induces type II to type I band alignment transformation. Scanning transmission electron microscopy reveals the dislocations at the interface that partially relieve the strain. Finally, we observe a distinctive electronic structure at the interface due to hetero-bonding.
Health and society in Chukotka: an overview
Dudarev, Alexey A.; Chupakhin, Valery S.; Odland, Jon Øyvind
2013-01-01
This study provides a historical overview of the changes in the socio-economic and health status of the population of Chukotka, from the Soviet to the post-Soviet period, with special attention paid to the circumstances of indigenous people. Past health studies in Chukotka are reviewed and key demographic and health indicator data presented. Since the 1990s, Chukotka's population has shrunk to a third of its former size due to emigration of non-indigenous and mostly younger people, with a corresponding increase in the mortality rate due to aging of the population. However, the indigenous population has remained stable. Among the most important causes of mortality are injuries. The living conditions of indigenous people continue to be a cause of concern, beset by high rates of poverty, unemployment, alcoholism, suicide and a variety of infectious diseases, such as tuberculosis and sexually transmitted infections. The economy, general infrastructure and health care system of Chukotka have been considerably improved by the Abramovich administration in the 2000s. PMID:23518623
Self-Critical Appropriation: An Assessment of Bauman's View of Education in Liquid Modernity
ERIC Educational Resources Information Center
Sarid, Ariel
2017-01-01
Zygmunt Bauman has devoted considerable amount of attention to the discussion of the educational challenges in liquid modernity. While a good deal of professional attention has been given to Bauman's concept in various fields and disciplines, his views on education have received relatively little response by educational theorists and…
ERIC Educational Resources Information Center
Özoglu, Murat; Beyazit, Yildirim
2015-01-01
Policies toward fostering a more balanced distribution of teacher quality have garnered considerable attention from researchers and policymakers around the world. This attention has been motivated largely by the widely acknowledged educational goal of providing quality education for all children. Equipped with similar policy concerns, this study…
Applying Human Computation Methods to Information Science
ERIC Educational Resources Information Center
Harris, Christopher Glenn
2013-01-01
Human Computation methods such as crowdsourcing and games with a purpose (GWAP) have each recently drawn considerable attention for their ability to synergize the strengths of people and technology to accomplish tasks that are challenging for either to do well alone. Despite this increased attention, much of this transformation has been focused on…
ERIC Educational Resources Information Center
Prosser, Brenton J.
2008-01-01
A psycho-medical discourse that explains behavioural dysfunction through neurological deficit has dominated debate about attention deficit hyperactivity disorder (ADHD). However, if only medical questions are asked, only medical answers will be found, resulting in more or less drug treatment. When behavioural dysfunction results in impairment…
ERIC Educational Resources Information Center
Fabiano, Gregory A.
2014-01-01
Attention-deficit/hyperactivity disorder is now widely conceptualized as a life course-persistent disorder, present from early childhood, and it results in pronounced impairment in functioning within educational settings, including high school. Current intervention approaches are briefly reviewed, and an approach to framing interventions within a…
Sources of uncertainty in annual forest inventory estimates
Ronald E. McRoberts
2000-01-01
Although design and estimation aspects of annual forest inventories have begun to receive considerable attention within the forestry and natural resources communities, little attention has been devoted to identifying the sources of uncertainty inherent in these systems or to assessing the impact of those uncertainties on the total uncertainties of inventory estimates....
Roll Call: The Importance of Teacher Attendance
ERIC Educational Resources Information Center
Joseph, Nithya; Waymack, Nancy; Zielaski, Daniel
2014-01-01
While policymakers have been directing considerable attention to teacher effectiveness, one basic aspect of effectiveness has received relatively little attention: teacher attendance. No matter how engaging or talented teachers may be, they can only have an impact on student learning if they are in the classroom. This paper asks a simple question:…
Attentional Resources in Visual Tracking through Occlusion: The High-Beams Effect
ERIC Educational Resources Information Center
Flombaum, Jonathan I.; Scholl, Brian J.; Pylyshyn, Zenon W.
2008-01-01
A considerable amount of research has uncovered heuristics that the visual system employs to keep track of objects through periods of occlusion. Relatively little work, by comparison, has investigated the online resources that support this processing. We explored how attention is distributed when featurally identical objects become occluded during…
A Review of Mindfulness Research Related to Alleviating Math and Science Anxiety
ERIC Educational Resources Information Center
Ahmed, Khalique; Trager, Bradley; Rodwell, Megan; Foinding, Linda; Lopez, Cori
2017-01-01
Defined as nonjudgmentally paying attention to the present moment (Kabat-Zinn, 1994), modern-day mindfulness has gained considerable attention in various science fields. However, despite this growth, many uses of mindfulness remain unexplored. In this paper, we focus on the application of mindfulness programs in educational settings, specifically…
"The Customer Is Always Right?": Student Discourse about Higher Education in Australia
ERIC Educational Resources Information Center
White, Naomi Rosh
2007-01-01
Changed funding arrangements and views of education have resulted in a re-prioritization of activities and practices in Australian universities. While considerable research attention has been given to the consequences of these changes for university policies and the activities of academic staff, less attention has been given to how students…
Using neuronal populations to study the mechanisms underlying spatial and feature attention
Cohen, Marlene R.; Maunsell, John H.R.
2012-01-01
Summary Visual attention affects both perception and neuronal responses. Whether the same neuronal mechanisms mediate spatial attention, which improves perception of attended locations, and non-spatial forms of attention has been a subject of considerable debate. Spatial and feature attention have similar effects on individual neurons. Because visual cortex is retinotopically organized, however, spatial attention can co-modulate local neuronal populations, while feature attention generally requires more selective modulation. We compared the effects of feature and spatial attention on local and spatially separated populations by recording simultaneously from dozens of neurons in both hemispheres of V4. Feature and spatial attention affect the activity of local populations similarly, modulating both firing rates and correlations between pairs of nearby neurons. However, while spatial attention appears to act on local populations, feature attention is coordinated across hemispheres. Our results are consistent with a unified attentional mechanism that can modulate the responses of arbitrary subgroups of neurons. PMID:21689604
Tuned Normalization Explains the Size of Attention Modulations
Ni, Amy M.; Ray, Supratim; Maunsell, John H. R.
2012-01-01
SUMMARY The effect of attention on firing rates varies considerably within a single cortical area. The firing rate of some neurons is greatly modulated by attention while others are hardly affected. The reason for this variability across neurons is unknown. We found that the variability in attention modulation across neurons in area MT of macaques can be well explained by variability in the strength of tuned normalization across neurons. The presence of tuned normalization also explains a striking asymmetry in attention effects within neurons: when two stimuli are in a neuron’s receptive field, directing attention to the preferred stimulus modulates firing rates more than directing attention to the non-preferred stimulus. These findings show that much of the neuron-to-neuron variability in modulation of responses by attention depends on variability in the way the neurons process multiple stimuli, rather than differences in the influence of top-down signals related to attention. PMID:22365552
Tuned normalization explains the size of attention modulations.
Ni, Amy M; Ray, Supratim; Maunsell, John H R
2012-02-23
The effect of attention on firing rates varies considerably within a single cortical area. The firing rate of some neurons is greatly modulated by attention while others are hardly affected. The reason for this variability across neurons is unknown. We found that the variability in attention modulation across neurons in area MT of macaques can be well explained by variability in the strength of tuned normalization across neurons. The presence of tuned normalization also explains a striking asymmetry in attention effects within neurons: when two stimuli are in a neuron's receptive field, directing attention to the preferred stimulus modulates firing rates more than directing attention to the nonpreferred stimulus. These findings show that much of the neuron-to-neuron variability in modulation of responses by attention depends on variability in the way the neurons process multiple stimuli, rather than differences in the influence of top-down signals related to attention. Copyright © 2012 Elsevier Inc. All rights reserved.
Wang, C; Ouyang, H; Maclaren, V; Yin, Y; Shao, B; Boland, A; Tian, Y
2007-11-01
The Sloping Land Conversion Program (also known as "Grain for Green" or the Upland Conversion Program) for converting cropland to forest is one of China's most ambitious environmental initiatives, and is one of the world's largest land-conservation programs with a budget of RMB 337 billion (over US$ 40 billion). Although environmental impacts have played a vital role in the general reasoning and argumentation for forest plantations, environmental impact analyses have often received less attention than economic analyses in the planning of plantation forestry projects. The overall goal of this paper is to evaluate the program's environmental impact considering the farmer's interests and the potential social benefits due to carbon sequestration in different scenarios based on household and field survey data in Dunhua County. Our findings are that: (1) in many cases, the program did not give adequate consideration to land productivity and environmental heterogeneity when selecting plots; (2) more than half of the reforestation plots were on flat cropland (slopes of less than 5 degrees ); (3) in five of the eight townships, net incomes on reforested land were substantially above or below previous crop incomes, raising questions about the efficiency of the allocation of compensation to farmers participating in the program; (4) the potential carbon co-benefit increased the NPV of the program by 5954-7009 RMB/ha. In conclusion, we recommend that more attention should be paid to the quality of reforestation programs rather than just their scale and note that consideration of potential carbon sequestration co-benefits enhances the benefits of cropland conversion programs.
Guez, Jonathan; Naveh-Benjamin, Moshe
2013-01-01
In this study, we evaluate the conceptualization of encoding and retrieval processes established in previous studies that used a divided attention (DA) paradigm. These studies indicated that there were considerable detrimental effects of DA at encoding on later memory performance, but only minimal effects, if any, on divided attention at retrieval. We suggest that this asymmetry in the effects of DA on memory can be due, at least partially, to a confound between the memory phase (encoding and retrieval) and the memory requirements of the task (memory “for” encoded information versus memory “at” test). To control for this confound, we tested memory for encoded information and for retrieved information by introducing a second test that assessed memory for the retrieved information from the first test. We report the results of four experiments that use measures of memory performance, retrieval latency, and performance on the concurrent task, all of which consistently show that DA at retrieval strongly disrupts later memory for the retrieved episode, similarly to the effects of DA at encoding. We suggest that these symmetrical disruptive effects of DA at encoding and retrieval on later retrieval reflect a disruption of an episodic buffer (EB) or episodic register component (ER), rather than a failure of encoding or retrieval operations per se. PMID:24040249
Guez, Jonathan; Naveh-Benjamin, Moshe
2013-01-01
In this study, we evaluate the conceptualization of encoding and retrieval processes established in previous studies that used a divided attention (DA) paradigm. These studies indicated that there were considerable detrimental effects of DA at encoding on later memory performance, but only minimal effects, if any, on divided attention at retrieval. We suggest that this asymmetry in the effects of DA on memory can be due, at least partially, to a confound between the memory phase (encoding and retrieval) and the memory requirements of the task (memory "for" encoded information versus memory "at" test). To control for this confound, we tested memory for encoded information and for retrieved information by introducing a second test that assessed memory for the retrieved information from the first test. We report the results of four experiments that use measures of memory performance, retrieval latency, and performance on the concurrent task, all of which consistently show that DA at retrieval strongly disrupts later memory for the retrieved episode, similarly to the effects of DA at encoding. We suggest that these symmetrical disruptive effects of DA at encoding and retrieval on later retrieval reflect a disruption of an episodic buffer (EB) or episodic register component (ER), rather than a failure of encoding or retrieval operations per se.
NASA Technical Reports Server (NTRS)
Childers, Brooks A.; Snow, Walter L.
1990-01-01
Considerations for acquiring and analyzing 30 Hz video frames from charge coupled device (CCD) cameras mounted in the wing tips of a Beech T-34 aircraft are described. Particular attention is given to the characterization and correction of optical distortions inherent in the data.
ERIC Educational Resources Information Center
Buys, L.; Aird, R.; Miller, E.
2012-01-01
Background: Considerable attention is currently being directed towards both active ageing and the revising of standards for disability services within Australia and internationally. Yet, to date, no consideration appears to have been given to ways to promote active ageing among older adults with intellectual disabilities (IDs). Methods:…
Homelessness in Urban America: A Review of the Literature.
ERIC Educational Resources Information Center
Sommer, Heidi
In the 1980s, homelessness attracted considerable attention from the media, advocates, politicians, and the public. Virtually every sector of society and the government responded. Interest in the issue has waned considerably since then, but the problem continues growing, particularly in large urban areas. While public policies address the problem,…
Technology meets ergonomics in the dental clinic: new toys for old games?
Rucker, L M
2000-01-01
Although there have been considerable advances in dental equipment, the introduction of such technology has often been piecemeal and "rushed to market." As a result there has been insufficient attention paid to ergonomic considerations and a systematic approach to, and theory of, dental ergonomics have not yet emerged.
ERIC Educational Resources Information Center
Schweig, Jonathan David
2016-01-01
Student ratings, a critical component in policy efforts to assess and improve teaching, are often collected using questionnaires, and inferences about teachers are then based on aggregated student survey responses. While considerable attention has been paid to the reliability and validity of these aggregates, much less attention has been paid to…
ERIC Educational Resources Information Center
Stevens, Peter A. J.
2009-01-01
While British educational researchers have given considerable attention to issues of racism, little attention has been given to how pupils themselves perceive differential teacher treatment and how such views relate to pupils' claims of teacher racism and racial discrimination. This article employs ethnographic data gathered from one English and…
How Are 2-Year US Colleges Addressing Student Alcohol Use and Related Problems?
ERIC Educational Resources Information Center
Lenk, Kathleen M.; Nelson, Toben F.; Erickson, Darin J.; Toomey, Traci L.
2015-01-01
A considerable amount of attention and research has been dedicated to addressing alcohol use and related problems among students at 4-year colleges; however, less attention has been given to alcohol-related issues among students at 2-year technical/community colleges. This article describes research that expands on a study by Chiauzzi and…
Multimodal Evaluation in Academic Discussion Sessions: How Do Presenters Act and React?
ERIC Educational Resources Information Center
Querol-Julian, Mercedes; Fortanet-Gomez, Inmaculada
2012-01-01
Evaluation in academic discourse has received considerable attention from researchers. Much of the work on evaluation has focused, however, on written genres, and less attention has been paid to how evaluation unfolds in spoken academic genres. In our present research, we are interested in disclosing how the interpersonal meaning of evaluation is…
Sex Differences in the Experience of Unwanted Sexual Attention and Behaviors during Childhood
ERIC Educational Resources Information Center
Whealin, Julia M.; Zinzow, Heidi M.; Salstrom, Seoka A.; Jackson, Joan L.
2007-01-01
Girls receive considerable amounts of unwanted sexual attention (UWSA) and behaviors (UWSB). Less is known about boys' unwanted sexual experiences. The primary goal of this study was to obtain a descriptive profile of the types and perpetrators of childhood UWSA/B. Secondary goals were to examine sex differences in emotional reactions to UWSA/B…
ERIC Educational Resources Information Center
Chappell, Carolyn D.
2013-01-01
Recent national attention to issues of access, cost, and institutional performance in our public institutions of higher education have included numerous critiques and calls for reform at the level of board appointments and board governance. There has been considerable attention in both scholarly and popular media regarding governance issues…
More attentional focusing through binaural beats: evidence from the global-local task.
Colzato, Lorenza S; Barone, Hayley; Sellaro, Roberta; Hommel, Bernhard
2017-01-01
A recent study showed that binaural beats have an impact on the efficiency of allocating attention over time. We were interested to see whether this impact affects attentional focusing or, even further, the top-down control over irrelevant information. Healthy adults listened to gamma-frequency (40 Hz) binaural beats, which are assumed to increase attentional concentration, or a constant tone of 340 Hz (control condition) for 3 min before and during a global-local task. While the size of the congruency effect (indicating the failure to suppress task-irrelevant information) was unaffected by the binaural beats, the global-precedence effect (reflecting attentional focusing) was considerably smaller after gamma-frequency binaural beats than after the control condition. Our findings suggest that high-frequency binaural beats bias the individual attentional processing style towards a reduced spotlight of attention.
NASA Technical Reports Server (NTRS)
Mashhoon, B.; Grishchuk, L. P.
1980-01-01
Consideration is given to the possibility of detection of an isotropic background gravitational radiation of a stochastic nature by the method of Doppler tracking of spacecraft. Attention is given in the geometrical optics limit, to the general formula for the frequency shift of an electromagnetic signal in the gravitational radiation field, and it is shown to be gauge independent. The propagation of a free electromagnetic wave in a gravitational radiation field is examined with the conclusion that no resonance phenomena can be expected. Finally, the 'Doppler noise' due to a stochastic background is evaluated, and it is shown to depend on the total energy density of the background and a parameter that is a characteristic of the radiation spectrum and the detection system used.
Occurrence and biosynthesis of carotenoids in phytoplankton.
Huang, Jim Junhui; Lin, Shaoling; Xu, Wenwen; Cheung, Peter Chi Keung
2017-09-01
Naturally occurring carotenoids are important sources of antioxidants, anti-cancer compounds and anti-inflammatory agents and there is thus considerable market demand for their pharmaceutical applications. Carotenoids are widely distributed in marine and freshwater organisms including microalgae, phytoplankton, crustaceans and fish, as well as in terrestrial plants and birds. Recently, phytoplankton-derived carotenoids have received much attention due to their abundance, rapid rate of biosynthesis and unique composition. The carotenoids that accumulate in particular phytoplankton phyla are synthesized by specific enzymes and play unique physiological roles. This review focuses on studies related to the occurrence of carotenoids in different phytoplankton phyla and the molecular aspects of their biosynthesis. Recent biotechnological advances in the isolation and characterization of some representative carotenoid synthases in phytoplankton are also discussed. Copyright © 2017 Elsevier Inc. All rights reserved.
Surface effects on the thermal conductivity of silicon nanowires
NASA Astrophysics Data System (ADS)
Li, Hai-Peng; Zhang, Rui-Qin
2018-03-01
Thermal transport in silicon nanowires (SiNWs) has recently attracted considerable attention due to their potential applications in energy harvesting and generation and thermal management. The adjustment of the thermal conductivity of SiNWs through surface effects is a topic worthy of focus. In this paper, we briefly review the recent progress made in this field through theoretical calculations and experiments. We come to the conclusion that surface engineering methods are feasible and effective methods for adjusting nanoscale thermal transport and may foster further advancements in this field. Project supported by the National Natural Science Foundation ofChina (Grant No. 11504418), China Scholarship Council (Grant No. 201706425053), Basic Research Program in Shenzhen, China (Grant No. JCYJ20160229165210666), and the Fundamental Research Funds for the Central Universities of China (Grant No. 2015XKMS075).
Silk Fibroin-Based Nanoparticles for Drug Delivery
Zhao, Zheng; Li, Yi; Xie, Mao-Bin
2015-01-01
Silk fibroin (SF) is a protein-based biomacromolecule with excellent biocompatibility, biodegradability and low immunogenicity. The development of SF-based nanoparticles for drug delivery have received considerable attention due to high binding capacity for various drugs, controlled drug release properties and mild preparation conditions. By adjusting the particle size, the chemical structure and properties, the modified or recombinant SF-based nanoparticles can be designed to improve the therapeutic efficiency of drugs encapsulated into these nanoparticles. Therefore, they can be used to deliver small molecule drugs (e.g., anti-cancer drugs), protein and growth factor drugs, gene drugs, etc. This paper reviews recent progress on SF-based nanoparticles, including chemical structure, properties, and preparation methods. In addition, the applications of SF-based nanoparticles as carriers for therapeutic drugs are also reviewed. PMID:25749470
NASA Technical Reports Server (NTRS)
2003-01-01
A subsidiary of SI Diamond Technology, Inc., Applied Nanotech, of Austin, Texas, is creating a buzz among various technology firms and venture capital groups interested in the company s progressive research on carbon-related field emission devices, including carbon nanotubes, filaments of pure carbon less than one ten-thousandth the width of human hair. Since their discovery in 1991, carbon nanotubes have gained considerable attention due to their unique physical properties. For example, a single perfect carbon nanotube can range from 10 to 100 times stronger than steel, per unit weight. Recent studies also indicate that the nanotubes may be the best heat-conducting material in existence. These properties, combined with the ease of growing thin films or nanotubes by a variety of deposition techniques, make the carbon-based material one of the most desirable for cold field emission cathodes.
Rotational effects on impingement cooling
NASA Technical Reports Server (NTRS)
Epstein, A. H.; Kerrebrock, J. L.; Koo, J. J.; Preiser, U. Z.
1987-01-01
The present consideration of rotation effects on heat transfer in a radially exhausted, impingement-cooled turbine blade model gives attention to experimental results for Reynolds and Rossby numbers and blade/coolant temperature ratio values that are representative of small gas turbine engines. On the basis of a model that encompasses the effects of Coriolis force and buoyancy on heat transfer, bouyancy is identified as the cause of an average Nusselt number that is 20-30 percent lower than expected from previous nonrotating data. A heuristic model is proposed which predicts that the impingement jets nearest the blade roots should deflect inward, due to a centripetal force generated by their tangential velocity counter to the blade motion. Potentially serious thermal stresses must be anticipated from rotation effects in the course of blade design.
Covalently bonded networks through surface-confined polymerization
NASA Astrophysics Data System (ADS)
El Garah, Mohamed; MacLeod, Jennifer M.; Rosei, Federico
2013-07-01
The prospect of synthesizing ordered, covalently bonded structures directly on a surface has recently attracted considerable attention due to its fundamental interest and for potential applications in electronics and photonics. This prospective article focuses on efforts to synthesize and characterize epitaxial one- and two-dimensional (1D and 2D, respectively) polymeric networks on single crystal surfaces. Recent studies, mostly performed using scanning tunneling microscopy (STM), demonstrate the ability to induce polymerization based on Ullmann coupling, thermal dehalogenation and dehydration reactions. The 2D polymer networks synthesized to date have exhibited structural limitations and have been shown to form only small domains on the surface. We discuss different approaches to control 1D and 2D polymerization, with particular emphasis on the surface phenomena that are critical to the formation of larger ordered domains.
Fotso, Jean-Christophe
2007-03-01
This paper examines levels and trends of urban-rural differentials in child malnutrition, and investigates whether residual differences exist between urban and rural areas, given comparable measures of socioeconomic status (SES) of households and communities. Using data from Demographic and Health Surveys of 15 sub-Saharan African countries, and multilevel modelling, it shows that urban-rural differentials are considerable in all countries, that they have narrowed in most countries due primarily to an increase in urban malnutrition, and have widened in few countries as a result of sharp decline in urban malnutrition. These urban-rural gaps are abolished in almost all countries when SES is controlled. These results suggest that policies and programs contributing to the attainment of the MDGs should pay particular attention to the urban poor.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1994-02-10
The project establishes the necessary experiment and laboratory facilities at Xavier University. This phase of the work has taken a considerable amount of time, due to the limited laboratory space and the involved administrative policies and procedures in procuring the necessary chemicals, glassware and auxiliary supplies. Though there still remain some minor problems with space, the laboratory is now equipped for preparation of catalysts. During this period, the authors focused their attention toward analyzing the magnetic nature of extensively used trimetallic catalyst system Cu-Co-Cr for the production of higher alcohols. The authors decided to investigate the effect of method ofmore » preparation and intermetallic ratio on the magnetic behavior of the system.« less
Non-Hermitian optics in atomic systems
NASA Astrophysics Data System (ADS)
Zhang, Zhaoyang; Ma, Danmeng; Sheng, Jiteng; Zhang, Yiqi; Zhang, Yanpeng; Xiao, Min
2018-04-01
A wide class of non-Hermitian Hamiltonians can possess entirely real eigenvalues when they have parity-time (PT) symmetric potentials. Recently, this family of non-Hermitian systems has attracted considerable attention in diverse areas of physics due to their extraordinary properties, especially in optical systems based on solid-state materials, such as coupled gain-loss waveguides and microcavities. Considering the desired refractive index can be effectively manipulated through atomic coherence, it is important to realize such non-Hermitian optical potentials and further investigate their distinct properties in atomic systems. In this paper, we review the recent theoretical and experimental progress of non-Hermitian optics with coherently prepared multi-level atomic configurations. The realizations of (anti-) PT symmetry with different schemes have extensively demonstrated the special optical properties of non-Hermitian optical systems with atomic coherence.
Formal implementation of a performance evaluation model for the face recognition system.
Shin, Yong-Nyuo; Kim, Jason; Lee, Yong-Jun; Shin, Woochang; Choi, Jin-Young
2008-01-01
Due to usability features, practical applications, and its lack of intrusiveness, face recognition technology, based on information, derived from individuals' facial features, has been attracting considerable attention recently. Reported recognition rates of commercialized face recognition systems cannot be admitted as official recognition rates, as they are based on assumptions that are beneficial to the specific system and face database. Therefore, performance evaluation methods and tools are necessary to objectively measure the accuracy and performance of any face recognition system. In this paper, we propose and formalize a performance evaluation model for the biometric recognition system, implementing an evaluation tool for face recognition systems based on the proposed model. Furthermore, we performed evaluations objectively by providing guidelines for the design and implementation of a performance evaluation system, formalizing the performance test process.
VHF command system study. [spectral analysis of GSFC VHF-PSK and VHF-FSK Command Systems
NASA Technical Reports Server (NTRS)
Gee, T. H.; Geist, J. M.
1973-01-01
Solutions are provided to specific problems arising in the GSFC VHF-PSK and VHF-FSK Command Systems in support of establishment and maintenance of Data Systems Standards. Signal structures which incorporate transmission on the uplink of a clock along with the PSK or FSK data are considered. Strategies are developed for allocating power between the clock and data, and spectral analyses are performed. Bit error probability and other probabilities pertinent to correct transmission of command messages are calculated. Biphase PCM/PM and PCM/FM are considered as candidate modulation techniques on the telemetry downlink, with application to command verification. Comparative performance of PCM/PM and PSK systems is given special attention, including implementation considerations. Gain in bit error performance due to coding is also considered.
Design consideration of high voltage Ga2O3 vertical Schottky barrier diode with field plate
NASA Astrophysics Data System (ADS)
Choi, J.-H.; Cho, C.-H.; Cha, H.-Y.
2018-06-01
Gallium oxide (Ga2O3) based vertical Schottky barrier diodes (SBDs) were designed for high voltage switching applications. Since p-type Ga2O3 epitaxy growth or p-type ion implantation technique has not been developed yet, a field plate structure was employed in this study to maximize the breakdown voltage by suppressing the electric field at the anode edge. TCAD simulation was used for the physical analysis of Ga2O3 SBDs from which it was found that careful attention must be paid to the insulator under the field plate. Due to the extremely high breakdown field property of Ga2O3, an insulator with both high permittivity and high breakdown field must be used for the field plate formation.
Disk space and load time requirements for eye movement biometric databases
NASA Astrophysics Data System (ADS)
Kasprowski, Pawel; Harezlak, Katarzyna
2016-06-01
Biometric identification is a very popular area of interest nowadays. Problems with the so-called physiological methods like fingerprints or iris recognition resulted in increased attention paid to methods measuring behavioral patterns. Eye movement based biometric (EMB) identification is one of the interesting behavioral methods and due to the intensive development of eye tracking devices it has become possible to define new methods for the eye movement signal processing. Such method should be supported by an efficient storage used to collect eye movement data and provide it for further analysis. The aim of the research was to check various setups enabling such a storage choice. There were various aspects taken into consideration, like disk space usage, time required for loading and saving whole data set or its chosen parts.
Mammalian Metallothionein-2A and Oxidative Stress
Ling, Xue-Bin; Wei, Hong-Wei; Wang, Jun; Kong, Yue-Qiong; Wu, Yu-You; Guo, Jun-Li; Li, Tian-Fa; Li, Ji-Ke
2016-01-01
Mammalian metallothionein-2A (MT2A) has received considerable attention in recent years due to its crucial pathophysiological role in anti-oxidant, anti-apoptosis, detoxification and anti-inflammation. For many years, most studies evaluating the effects of MT2A have focused on reactive oxygen species (ROS), as second messengers that lead to oxidative stress injury of cells and tissues. Recent studies have highlighted that oxidative stress could activate mitogen-activated protein kinases (MAPKs), and MT2A, as a mediator of MAPKs, to regulate the pathogenesis of various diseases. However, the molecule mechanism of MT2A remains elusive. A deeper understanding of the functional, biochemical and molecular characteristics of MT2A would be identified, in order to bring new opportunities for oxidative stress therapy. PMID:27608012
Actinide Waste Forms and Radiation Effects
NASA Astrophysics Data System (ADS)
Ewing, R. C.; Weber, W. J.
Over the past few decades, many studies of actinides in glasses and ceramics have been conducted that have contributed substantially to the increased understanding of actinide incorporation in solids and radiation effects due to actinide decay. These studies have included fundamental research on actinides in solids and applied research and development related to the immobilization of the high level wastes (HLW) from commercial nuclear power plants and processing of nuclear weapons materials, environmental restoration in the nuclear weapons complex, and the immobilization of weapons-grade plutonium as a result of disarmament activities. Thus, the immobilization of actinides has become a pressing issue for the twenty-first century (Ewing, 1999), and plutonium immobilization, in particular, has received considerable attention in the USA (Muller et al., 2002; Muller and Weber, 2001). The investigation of actinides and
Scope of Attention, Control of Attention, and Intelligence in Children and Adults
Cowan, Nelson; Fristoe, Nathanael M.; Elliott, Emily M.; Brunner, Ryan P.; Saults, J. Scott
2006-01-01
Recent experimentation has shown that cognitive aptitude measures are predicted by tests of the scope of an individual’s attention or capacity in simple working-memory tasks, and also by the ability to control attention. However, these experiments do not indicate how separate or related the scope and control of attention are. An experiment with 52 children 10 to 11 years old and 52 college students included measures of the scope and control of attention as well as verbal and nonverbal aptitude measures. The children showed little evidence of using sophisticated attentional control, but the scope of attention predicted intelligence in that group. In adults, the scope and control of attention both varied among individuals, and they accounted for considerable individual variance in intelligence. About 1/3 that variance was shared between scope and control, the rest being unique to one or the other. Scope and control of attention appear to be related but distinct contributors to intelligence. PMID:17489300
Bhandari, Jayant; Daya, Ritesh; Mishra, Ram K
2016-09-01
The 5-choice serial reaction time task (5-CSRTT) is an automated operant conditioning task that measures rodent attention. The task allows the measurement of several parameters such as response accuracy, speed of processing, motivation, and impulsivity. The task has been widely used to investigate attentional processes in rodents for attention deficit and hyperactivity disorder and has expanded to other illnesses such as Alzheimer's disease, depression, and schizophrenia. The 5-CSRTT is accompanied with two significant caveats: a time intensive training period and largely varied individual rat capability to learn and perform the task. Here we provide a regimented acquisition protocol to enhance training for the 5-CSRTT and discuss important considerations for researchers using the 5-CSRTT. We offer guidelines to ensure that inferences on performance in the 5-CSRTT are in fact a result of experimental manipulation rather than training differences, or individual animal capability. According to our findings only rats that have been trained successfully within a limited time frame should be used for the remainder of the study. Currently the 5-CSRTT employs a training period of variable duration and procedure, and its inferences on attention must overcome heterogeneous innate animal differences. The 5-CSRTT offers valuable and valid insights on various rodent attentional processes and their translation to the underpinnings of illnesses such as schizophrenia. The recommendations made here provide important criteria to ensure inferences made from this task are in fact relevant to the attentional processes being measured. Copyright © 2016 Elsevier B.V. All rights reserved.
Mimetic Theory and Scapegoating in the Age of Cyberbullying: The Case of Phoebe Prince
ERIC Educational Resources Information Center
Norman, James O'Higgins; Connolly, Justin
2011-01-01
Whilst traditional forms of bullying have and continue to receive considerable attention in the literature, research on technology-enabled bullying remains in an embryonic stage and considerable deficits exist in our understanding of the nature, extent, dynamics and consequents of this new form of bullying. Of the limited studies that exist on…
ERIC Educational Resources Information Center
Edwards, Finley
2012-01-01
School start times vary considerably, both across the nation and within individual communities, with some schools beginning earlier than 7:30 a.m. and others after 9:00 a.m. Proponents of later start times, who have received considerable media attention in recent years, argue that many students who have to wake up early for school do not get…
A unique role of endogenous visual-spatial attention in rapid processing of multiple targets
Guzman, Emmanuel; Grabowecky, Marcia; Palafox, German; Suzuki, Satoru
2012-01-01
Visual spatial attention can be exogenously captured by a salient stimulus or can be endogenously allocated by voluntary effort. Whether these two attention modes serve distinctive functions is debated, but for processing of single targets the literature suggests superiority of exogenous attention (it is faster acting and serves more functions). We report that endogenous attention uniquely contributes to processing of multiple targets. For speeded visual discrimination, response times are faster for multiple redundant targets than for single targets due to probability summation and/or signal integration. This redundancy gain was unaffected when attention was exogenously diverted from the targets, but was completely eliminated when attention was endogenously diverted. This was not due to weaker manipulation of exogenous attention because our exogenous and endogenous cues similarly affected overall response times. Thus, whereas exogenous attention is superior for processing single targets, endogenous attention plays a unique role in allocating resources crucial for rapid concurrent processing of multiple targets. PMID:21517209
ERIC Educational Resources Information Center
Fabiano, Gregory A.; Vujnovic, Rebecca K.; Pelham, William E.; Waschbusch, Daniel A.; Massetti, Greta M.; Pariseau, Meaghan E.; Naylor, Justin; Yu, Jihnhee; Robins, Melissa; Carnefix, Tarah; Greiner, Andrew R.; Volker, Martin
2010-01-01
Children with attention deficit hyperactivity disorder (ADHD) make up a considerable proportion of students who receive special education services in schools. The present study aimed to enhance the outcomes of students with ADHD in special education settings by using a daily report card (DRC). Thirty-three children with ADHD in special education…
Benefit segmentation of the fitness market.
Brown, J D
1992-01-01
While considerate attention is being paid to the fitness and wellness needs of people by healthcare and related marketing organizations, little research attention has been directed to identifying the market segments for fitness based upon consumers' perceived benefits of fitness. This article describes three distinct segments of fitness consumers comprising an estimated 50 percent of households. Implications for marketing strategies are also presented.
Sud, Sachin; Cuthbertson, Brian H
2011-10-01
The article reviews the methods of health economic analysis (HEA) in clinical trials of critically ill patients. Emphasis is placed on the usefulness of HEA in the context of positive and 'no effect' studies, with recent examples. The need to control costs and promote effective spending in caring for the critically ill has garnered considerable attention due to the high cost of critical illness. Many clinical trials focus on short-term mortality, ignoring costs and quality of life, and fail to change clinical practice or promote efficient use of resources. Incorporating HEA into clinical trials is a possible solution. Such studies have shown some interventions, although expensive, provide good value, whereas others should be withdrawn from clinical practice. Incorporating HEA into randomized controlled trials (RCTs) requires careful attention to collect all relevant costs. Decision trees, modeling assumptions and methods for collecting costs and measuring outcomes should be planned and published beforehand to minimize bias. Costs and cost-effectiveness are potentially useful outcomes in RCTs of critically ill patients. Future RCTs should incorporate parallel HEA to provide both economic outcomes, which are important to the community, alongside patient-centered outcomes, which are important to individuals.
Sonuga-Barke, Edmund J S
2005-06-01
Until recently, causal models of attention-deficit/hyperactivity disorder (ADHD) have tended to focus on the role of common, simple, core deficits. One such model highlights the role of executive dysfunction due to deficient inhibitory control resulting from disturbances in the frontodorsal striatal circuit and associated mesocortical dopaminergic branches. An alternative model presents ADHD as resulting from impaired signaling of delayed rewards arising from disturbances in motivational processes, involving frontoventral striatal reward circuits and mesolimbic branches terminating in the ventral striatum, particularly the nucleus accumbens. In the present article, these models are elaborated in two ways. First, they are each placed within their developmental context by consideration of the role of person x environment correlation and interaction and individual adaptation to developmental constraint. Second, their relationship to one another is reviewed in the light of recent data suggesting that delay aversion and executive functions might each make distinctive contributions to the development of the disorder. This provides an impetus for theoretical models built around the idea of multiple neurodevelopmental pathways. The possibility of neuropathologic heterogeneity in ADHD is likely to have important implications for the clinical management of the condition, potentially impacting on both diagnostic strategies and treatment options.
Attention Alters Perceived Attractiveness.
Störmer, Viola S; Alvarez, George A
2016-04-01
Can attention alter the impression of a face? Previous studies showed that attention modulates the appearance of lower-level visual features. For instance, attention can make a simple stimulus appear to have higher contrast than it actually does. We tested whether attention can also alter the perception of a higher-order property-namely, facial attractiveness. We asked participants to judge the relative attractiveness of two faces after summoning their attention to one of the faces using a briefly presented visual cue. Across trials, participants judged the attended face to be more attractive than the same face when it was unattended. This effect was not due to decision or response biases, but rather was due to changes in perceptual processing of the faces. These results show that attention alters perceived facial attractiveness, and broadly demonstrate that attention can influence higher-level perception and may affect people's initial impressions of one another. © The Author(s) 2016.
Attentive Tracking Disrupts Feature Binding in Visual Working Memory
Fougnie, Daryl; Marois, René
2009-01-01
One of the most influential theories in visual cognition proposes that attention is necessary to bind different visual features into coherent object percepts (Treisman & Gelade, 1980). While considerable evidence supports a role for attention in perceptual feature binding, whether attention plays a similar function in visual working memory (VWM) remains controversial. To test the attentional requirements of VWM feature binding, here we gave participants an attention-demanding multiple object tracking task during the retention interval of a VWM task. Results show that the tracking task disrupted memory for color-shape conjunctions above and beyond any impairment to working memory for object features, and that this impairment was larger when the VWM stimuli were presented at different spatial locations. These results demonstrate that the role of visuospatial attention in feature binding is not unique to perception, but extends to the working memory of these perceptual representations as well. PMID:19609460
Quantifying ADHD classroom inattentiveness, its moderators, and variability: a meta-analytic review.
Kofler, Michael J; Rapport, Mark D; Alderson, R Matt
2008-01-01
Most classroom observation studies have documented significant deficiencies in the classroom attention of children with attention-deficit/hyperactivity disorder (ADHD) compared to their typically developing peers. The magnitude of these differences, however, varies considerably and may be influenced by contextual, sampling, diagnostic, and observational differences. Meta-analysis of 23 between-group classroom observation studies using weighted regression, publication bias, goodness of fit, best case, and original metric analyses. Across studies, a large effect size (ES = .73) was found prior to consideration of potential moderators. Weighted regression, best case, and original metric estimation indicate that this effect may be an underestimation of the classroom visual attention deficits of children with ADHD. Several methodological factors-classroom environment, sample characteristics, diagnostic procedures, and observational coding schema-differentially affect observed rates of classroom attentive behavior for children with ADHD and typically developing children. After accounting for these factors, children with ADHD were on-task approximately 75% of the time compared to 88% for their classroom peers (ES = 1.40). Children with ADHD were also more variable in their attentive behavior across studies. The present study confirmed that children with ADHD exhibit deficient and more variable visual attending to required stimuli in classroom settings and provided an aggregate estimation of the magnitude of these deficits at the group level. It also demonstrated the impact of situational, sampling, diagnostic, and observational variables on observed rates of on-task behavior.
Rankin, Eric D
2014-04-01
Mourning has received considerable attention in the psychoanalytic literature. Beginning with Freud's 1917 investigation, the central role of mourning in psychical development via identification has been articulated and subsequently elaborated upon by various authors (e.g., Klein, 1940; Schafer, 2005). Forgiveness, on the other hand, has until recently received considerably less attention, perhaps because of the strong religious and moral connotations often associated with it (Lansky, 2009a). Contemporary writers exploring the psychoanalytic implications of mourning and forgiveness, however, have suggested the importance of both in normal psychical development. The purpose of this paper is to propose an integrated model of mourning and forgiveness and explore its potential role in nascent infant development.
The role of attention during retrieval in working-memory span: a dual-task study.
Healey, M Karl; Miyake, Akira
2009-04-01
We tested the hypothesis that retrieving target words in operation span (OSpan) involves attention-demanding processes. Participants completed the standard OSpan task and a modified version in which all equations preceded all target words. Recall took place under either full attention or easy versus hard divided-attention conditions. Recall suffered under divided attention with the recall decrement being greater for the hard secondary task. Moreover, secondary-task performance was disrupted more by the standard OSpan task than by the modified version with the hard secondary task showing the larger decrement. Finally, the time taken to start recalling the first word was considerably longer for the standard version than for the modified version. These results are consistent with the proposal that successful OSpan task performance in part involves the attention-demanding retrieval of targets from long-term memory.
Attention and Visuospatial Working Memory Share the Same Processing Resources
Feng, Jing; Pratt, Jay; Spence, Ian
2012-01-01
Attention and visuospatial working memory (VWM) share very similar characteristics; both have the same upper bound of about four items in capacity and they recruit overlapping brain regions. We examined whether both attention and VWM share the same processing resources using a novel dual-task costs approach based on a load-varying dual-task technique. With sufficiently large loads on attention and VWM, considerable interference between the two processes was observed. A further load increase on either process produced reciprocal increases in interference on both processes, indicating that attention and VWM share common resources. More critically, comparison among four experiments on the reciprocal interference effects, as measured by the dual-task costs, demonstrates no significant contribution from additional processing other than the shared processes. These results support the notion that attention and VWM share the same processing resources. PMID:22529826
ERIC Educational Resources Information Center
Lazarus, Sheryl; Thurlow, Martha
2015-01-01
Sound test security policies and procedures are needed to ensure test security and confidentiality, and to help prevent cheating. In this era when cheating on tests draws regular media attention, there is a need for thoughtful consideration of the ways in which possible test security measures may affect accessibility for some students with…
ERIC Educational Resources Information Center
Semo, Ronnie; Karmel, Tom
2011-01-01
In recent times social capital has received considerable attention because it is seen as having the potential to address many of the problems facing modern society, including the poor educational outcomes of considerable numbers of young people. This paper uses data from the Longitudinal Surveys of Australian Youth (LSAY) to explore the…
ERIC Educational Resources Information Center
Yell, Mitchell; Smith, Carl; Katsiyannis, Antonis; Losinski, Mickey
2018-01-01
In the past few years, the provision of mental health services in public schools has received considerable attention. When students with disabilities are eligible for special education and related services under the Individuals With Disabilities Education Act (IDEA), mental health services are required if such services are needed to provide…
The Central Nervous Connections Involved in the Vomiting Reflex
NASA Technical Reports Server (NTRS)
Brizzee, K. R.; Mehler, W. R.
1986-01-01
The vomiting reflex may be elicited by a number of different types or classes of stimuli involving many varieties of receptor structures and considerable diversity in afferent pathways and central connections. Central relay or mediating structures thus may vary widely according to the type of initial emetic stimulus. The emetic circuits which have been most completely delineated to date are probably those in which the Chemoreceptor Trigger Zone (CTZ) in the Area Postrema (AP) functions as a key mediating structure. Even in this system, however, there are large gaps in our knowledge of the nerve tracts and central nervous connections involved. Knowledge of most other emetic circuits subserving the emetic reflex resulting from many diverse types of stimuli such, for example, as emotional stress (e.g. psychogenic vomiting, Wruble et al. 1982), pain (e.g. testicular trauma), and chemical or mechanical irritation of the gastrointestinal tract or urinary tract is quite incomplete at this time, thus precluding any very adequate description of their central connections at present. One physiological system, however, which has received considerable attention recently in relation to the vomiting reflex elicited by motion stimuli is the vestibular system. Due to the paucity of data on central nervous connections of several or the non-vestibular types of emetic stimuli cited above, we will devote most of our attention in this brief review to the central connections of the vestibular system which seem likely to be involved in the vomiting response to motion stimuli. However, the latter part of the review will be concerned with the concept of the reticular vomiting centre in relation to the ParviCellular Reticular Formation (PCRF), and will thus probably pertain to all of the many classes of emetic stimuli since it will address the question of the final common emetic pathway.
More attention when speaking: does it help or does it hurt?
Nozari, Nazbanou; Thompson-Schill, Sharon L.
2013-01-01
Paying selective attention to a word in a multi-word utterance results in a decreased probability of error on that word (benefit), but an increased probability of error on the other words (cost). We ask whether excitation of the prefrontal cortex helps or hurts this cost. One hypothesis (the resource hypothesis) predicts a decrease in the cost due to the deployment of more attentional resources, while another (the focus hypothesis) predicts even greater costs due to further fine-tuning of selective attention. Our results are more consistent with the focus hypothesis: prefrontal stimulation caused a reliable increase in the benefit and a marginal increase in the cost of selective attention. To ensure that the effects are due to changes to the prefrontal cortex, we provide two checks: We show that the pattern of results is quite different if, instead, the primary motor cortex is stimulated. We also show that the stimulation-related benefits in the verbal task correlate with the stimulation-related benefits in an N-back task, which is known to tap into a prefrontal function. Our results shed light on how selective attention affects language production, and more generally, on how selective attention affects production of a sequence over time. PMID:24012690
Ren, Xuezhu; Altmeyer, Michael; Reiss, Siegbert; Schweizer, Karl
2013-02-01
Perceptual attention and executive attention represent two higher-order types of attention and associate with distinctly different ways of information processing. It is hypothesized that these two types of attention implicate different cognitive processes, which are assumed to account for the differential effects of perceptual attention and executive attention on fluid intelligence. Specifically, an encoding process is assumed to be crucial in completing the tasks of perceptual attention while two executive processes, updating and shifting, are stimulated in completing the tasks of executive attention. The proposed hypothesis was tested by means of an integrative approach combining experimental manipulations and psychometric modeling. In a sample of 210 participants the encoding process has proven indispensable in completing the tasks of perceptual attention, and this process accounted for a considerable part of fluid intelligence that was assessed by two figural reasoning tests. In contrast, the two executive processes, updating and shifting, turned out to be necessary in performance according to the tasks of executive attention and these processes accounted for a larger part of the variance in fluid intelligence than that of the processes underlying perceptual attention. Copyright © 2012 Elsevier B.V. All rights reserved.
Association between attention bias to threat and anxiety symptoms in children and adolescents.
Abend, Rany; de Voogd, Leone; Salemink, Elske; Wiers, Reinout W; Pérez-Edgar, Koraly; Fitzgerald, Amanda; White, Lauren K; Salum, Giovanni A; He, Jie; Silverman, Wendy K; Pettit, Jeremy W; Pine, Daniel S; Bar-Haim, Yair
2018-03-01
Considerable research links threat-related attention biases to anxiety symptoms in adults, whereas extant findings on threat biases in youth are limited and mixed. Inconsistent findings may arise due to substantial methodological variability and limited sample sizes, emphasizing the need for systematic research on large samples. The aim of this report is to examine the association between threat bias and pediatric anxiety symptoms using standardized measures in a large, international, multi-site youth sample. A total of 1,291 children and adolescents from seven research sites worldwide completed standardized attention bias assessment task (dot-probe task) and child anxiety symptoms measure (Screen for Child Anxiety Related Emotional Disorders). Using a dimensional approach to symptomatology, we conducted regression analyses predicting overall, and disorder-specific, anxiety symptoms severity, based on threat bias scores. Threat bias correlated positively with overall anxiety symptoms severity (ß = 0.078, P = .004). Furthermore, threat bias was positively associated specifically with social anxiety (ß = 0.072, P = .008) and school phobia (ß = 0.076, P = .006) symptoms severity, but not with panic, generalized anxiety, or separation anxiety symptoms. These associations were not moderated by age or gender. These findings indicate associations between threat bias and pediatric anxiety symptoms, and suggest that vigilance to external threats manifests more prominently in symptoms of social anxiety and school phobia, regardless of age and gender. These findings point to the role of attention bias to threat in anxiety, with implications for translational clinical research. The significance of applying standardized methods in multi-site collaborations for overcoming challenges inherent to clinical research is discussed. © 2017 Wiley Periodicals, Inc.
ERIC Educational Resources Information Center
Chacko, A.; Bedard, A. C.; Marks, D. J.; Feirsen, N.; Uderman, J. Z.; Chimiklis, A.; Rajwan, E.; Cornwell, M.; Anderson, L.; Zwilling, A.; Ramon, M.
2014-01-01
Background: Cogmed Working Memory Training (CWMT) has received considerable attention as a promising intervention for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in children. At the same time, methodological weaknesses in previous clinical trials call into question reported efficacy of CWMT. In particular, lack of equivalence…
Chen, Zhe; Rau, Pei-Luen Patrick; Chen, Cuiling
2014-05-01
The aim of the present study is to investigate Chinese handwriting on mobile touch devices, considering the effects of three characteristics of the human finger (type, length, and width) and three characteristics of Chinese characters (direction of the first stroke, number of strokes, and structure). Due to the popularity of touch devices in recent years, finger input for Chinese characters has attracted more attention from both industry and academia. However, previous studies have no systematical consideration on the effects of human finger and Chinese characters on Chinese handwriting performance. An experiment was reported in this article to illustrate the effects of the human finger and Chinese characters on the Chinese handwriting performance (i.e., input time, accuracy, number of protruding strokes, mental workload, satisfaction, and physical fatigue). The experiment results indicated that all six factors have significant effects on Chinese handwriting performance, especially on the input time, accuracy, and number of protruding strokes. Finger type, finger length, finger width, direction of the first stroke, number of strokes, and character structures are significantly influencing Chinese handwriting performance. These factors should be taken into more consideration in future research and the practical design for Chinese handwriting systems.
Ulfig, Krzysztof; Płaza, Grazyna; Terakowskip, Maciej; Janda-Ulfig, Katarzyna
2006-01-01
The study was to demonstrate the effect of sewage sludge open-air drying on the quantitative and qualitative composition of keratinolytic/keratinophilic and actidione-resistant fungi. The sludge was being dried for up to thirty days (on average fourteen days) at 25-30'C. The composition of these fungi was determined with the hair baiting method along with the dilution method, using the Wiegand medium supplemented with chloramphenicol (100 mgiL) and actidione (500 mg/L). The open-air drying altered the composition of keratinolytic fungi and considerably increased the population of keratinophilic and actidione-resistant fungi in the sludge. This phenomenon can be explained with that the drying process was associated with slow sludge moisture decrease, sludge laceration due to crumbling and the subsequent improvement of sludge aeration and organic matter biodegradation conditions. A considerable increase of fungal populations can be expected in sludges being dried in drying beds at wastewater treatment plants and in sludge-amended soils. Two sludge opportunistic fungi, i.e. Microsporum gypseum and Pseudallescheria boydii, require special attention from the epidemiological point of view. Sludge land applications may increase the number of these fungi in the environment and the subsequent risk to public health posed by them.
Code of Federal Regulations, 2011 CFR
2011-07-01
.... L. 95-454 and of the responsibilities of the Department of Defense. (f) OSC investigative requests involving classified information shall be accorded special attention and prompt consideration under existing...
NASA Technical Reports Server (NTRS)
Lamers, H. J. G. L. M.; Stalio, R.; Kondo, Y.
1978-01-01
Results are presented for a study of mass loss from A and late-B supergiants based on high-resolution mid-UV spectra obtained with the echelle spectrograph of the Balloon-borne Ultraviolet Stellar Spectrometer. Spectra of Alpha Cyg, Beta Ori, Eta Leo, and Alpha Lyr are compared in selected wavelength regions; particular attention is given to previous observations of each star, the Mg II and Fe II resonance lines, lines due to other ions, and evidence for mass ejection. The results indicate that mass loss from late-B and A supergiants is variable, that a considerable fraction of envelope material is ejected in 'puffs', and that the puffs may be due to photospheric instabilities. A mass-loss rate of about 1 hundred-millionth of a solar mass per year is derived for Alpha Cyg and shown to be two orders of magnitude smaller than the value determined from the observed IR excess. This discrepancy is attributed to excess ionization in the envelope.
Energy conversion in polyelectrolyte hydrogels
NASA Astrophysics Data System (ADS)
Olvera de La Cruz, Monica; Erbas, Aykut; Olvera de la Cruz Team
Energy conversion and storage have been an active field of research in nanotechnology parallel to recent interests towards renewable energy. Polyelectrolyte (PE) hydrogels have attracted considerable attention in this field due to their mechanical flexibility and stimuli-responsive properties. Ideally, when a hydrogel is deformed, applied mechanical work can be converted into electrostatic, elastic and steric-interaction energies. In this talk, we discuss the results of our extensive molecular dynamics simulations of PE hydrogels. We demonstrate that, on deformation, hydrogels adjust their deformed state predominantly by altering electrostatic interactions between their charged groups rather than excluded-volume and bond energies. This is due to the hydrogel's inherent tendency to preserve electro-neutrality in its interior, in combination with correlations imposed by backbone charges. Our findings are valid for a wide range of compression ratios and ionic strengths. The electrostatic-energy alterations that we observe in our MD simulations may induce pH or redox-potential changes inside the hydrogels. The resulting energetic difference can be harvested, for instance, analogously to a Carnot engine, or facilitated for sensor applications. Center for Bio-inspired Energy Science (CBES).
Reduced graphene oxide film based highly responsive infrared detector
NASA Astrophysics Data System (ADS)
Khan, Mustaque A.; Nanda, Karuna K.; Krupanidhi, Saluru B.
2017-08-01
Due to the unique optical properties, graphene can effectively be used for the detection of infrared light. In this regard, reduced graphene oxide (RGO) has drawn considerable attention in scientific society because of simplicity of preparation and tunable properties. Here, we report the synthesis of RGO by solvothermal reduction of graphene oxide (GO) in ethanol and the detection of infrared light (1064 and 1550 nm) with metal—RGO—metal configuration. We have observed that photocurrent, responsivity as well as the external quantum efficiency increase with C/O ratio. The responsivity value in near-infrared region can be as high as 1.34 A · W-1 and the external quantum efficiency is more than 100%. Response times of these devices are in the order of few seconds. Overall, the responsivity of our device is found to be better than many of the already reported values where graphene or reduced graphene oxide is the only active material. The high value of quantum efficiency is due to strong light absorption and the presence of mid-gap states band in RGOs.
Chu, Guang; Wang, Xuesi; Chen, Tianrui; Gao, Jianxiong; Gai, Fangyuan; Wang, Yu; Xu, Yan
2015-06-10
Plasmonic materials with large chiroptical activity at visible wavelength have attracted considerable attention due to their potential applications in metamaterials. Here we demonstrate a novel guest-host chiral nematic liquid crystal film composed of bulk self-co-assembly of the dispersed plasmonic silver nanowires (AgNWs) and cellulose nanocrystals (CNCs). The AgNWs-CNCs composite films show strong plasmonic optical activities, that are dependent on the chiral photonic properties of the CNCs host medium and orientation of the guest AgNWs. Tunable chiral distribution of the aligned anisotropic AgNWs with long-range order is obtained through the CNCs liquid crystal mediated realignment. The chiral plasmonic optical activity of the AgNWs-CNCs composite films can be tuned by changing the interparticle electrostatic repulsion between the CNCs nanorods and AgNWs. We also observe an electromagnetic energy transfer phenomena among the plasmonic bands of AgNWs, due to the modulation of the photonic band gap of the CNCs host matrix. This facile approach for fabricating chiral macrostructured plasmonic materials with optically tunable property is of interest for a variety of advanced optics applications.
NASA Astrophysics Data System (ADS)
Kim, Dae-Hyeong; Lee, Mincheol; Lee, Hyunjae
2016-05-01
Recent advances in soft electronics have attracted great attention, largely due to their potential applications in personalized, bio-integrated healthcare devices. The mechanical mismatch between conventional electronic/optoelectronic devices and soft human tissues/organs have presented many challenges, such as the low signalto- noise ratio of biosensors because of the incomplete integration of rigid devices with the body, inflammation and excessive immune responses of implanted stiff devices originated from friction and their foreign nature to biotic systems, and the considerable discomfort and consequent stress experienced by users when wearing/implanting these devices. Ultra-flexible and stretchable electronic devices are being highlighted due to their low system modulus and the intrinsic system-level softness that are important to solve these issues. Here, we describe our unique strategies for the nanomaterial synthesis and fabrication, their seamless assembly and integration, and the design and development of corresponding wearable healthcare devices and minimally invasive surgical tools. These bioelectronic systems fully utilize recent breakthroughs in unconventional soft electronics based on nanomaterials to address unsolved issues in clinical medicine and to provide new opportunities in the personalized healthcare.
Hydrogel Based Biosensors for In Vitro Diagnostics of Biochemicals, Proteins, and Genes.
Jung, Il Young; Kim, Ji Su; Choi, Bo Ram; Lee, Kyuri; Lee, Hyukjin
2017-06-01
Hydrogel-based biosensors have drawn considerable attention due to their various advantages over conventional detection systems. Recent studies have shown that hydrogel biosensors can be excellent alternative systems to detect a wide range of biomolecules, including small biochemicals, pathogenic proteins, and disease specific genes. Due to the excellent physical properties of hydrogels such as the high water content and stimuli-responsive behavior of cross-linked network structures, this system can offer substantial improvement for the design of novel detection systems for various diagnostic applications. The other main advantage of hydrogels is the role of biomimetic three-dimensional (3D) matrix immobilizing enzymes and aptamers within the detection systems, which enhances their stability. This provides ideal reaction conditions for enzymes and aptamers to interact with substrates within the aqueous environment of the hydrogel. In this review, we have highlighted various novel detection approaches utilizing the outstanding properties of the hydrogel. This review summarizes the recent progress of hydrogel-based biosensors and discusses their future perspectives and clinical limitations to overcome. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A study on the ergonomic assessment in the workplace
NASA Astrophysics Data System (ADS)
Tee, Kian Sek; Low, Eugene; Saim, Hashim; Zakaria, Wan Nurshazwani Wan; Khialdin, Safinaz Binti Mohd; Isa, Hazlita; Awad, M. I.; Soon, Chin Fhong
2017-09-01
Ergonomics has gained attention and take into consideration by the workers in the different fields of works recently. It has given a huge impact on the workers comfort which directly affects the work efficiency and productivity. The workers have claimed to suffer from the painful postures and injuries in their workplace. Musculoskeletal disorders (MSDs) is the most common problem frequently reported by the workers. This problem occurs due to the lack of knowledge and alertness from the workers to the ergonomic in their surroundings. This paper intends to review the approaches and instruments used by the previous works of the researchers in the evaluation of the ergonomics. The two main assessment methods often used for ergonomic evaluation are Rapid Upper Limb Assessment (RULA) and Rapid Entire Body Assessment (REBA). Popular devices are Inertial Measurement Units (IMU) and Microsoft Kinect.
Aloe Vera for Tissue Engineering Applications
Rahman, Shekh; Carter, Princeton; Bhattarai, Narayan
2017-01-01
Aloe vera, also referred as Aloe barbadensis Miller, is a succulent plant widely used for biomedical, pharmaceutical and cosmetic applications. Aloe vera has been used for thousands of years. However, recent significant advances have been made in the development of aloe vera for tissue engineering applications. Aloe vera has received considerable attention in tissue engineering due to its biodegradability, biocompatibility, and low toxicity properties. Aloe vera has been reported to have many biologically active components. The bioactive components of aloe vera have effective antibacterial, anti-inflammatory, antioxidant, and immune-modulatory effects that promote both tissue regeneration and growth. The aloe vera plant, its bioactive components, extraction and processing, and tissue engineering prospects are reviewed in this article. The use of aloe vera as tissue engineering scaffolds, gels, and films is discussed, with a special focus on electrospun nanofibers. PMID:28216559
Directionally Hiding Objects and Creating Illusions at Visible Wavelengths by Holography
Cheng, Qiluan; Wu, Kedi; Shi, Yile; Wang, Hui; Wang, Guo Ping
2013-01-01
Invisibility devices have attracted considerable attentions in the last decade. In addition to invisibility cloaks, unidirectional invisibility systems such as carpet-like cloaks and parity-time symmetric structures are also inspiring some specific researching interests due to their relatively simplifying design. However, unidirectional invisibility systems worked generally in just one certain illumination direction. Here, based on time-reversal principle, we present the design and fabrication of a kind of all-dielectric device that could directionally cancel objects and create illusions as the illuminating light was from different directions. Our devices were experimentally realized through holographic technology and could work for macroscopic objects with any reasonable size at visible wavelengths, and hence may take directional invisibility technology a big step towards interesting applications ranging from magic camouflaging, directional detection to super-resolution biomedical imaging. PMID:23756877
pH-Induced transformation of ligated Au25 to brighter Au23 nanoclusters.
Waszkielewicz, Magdalena; Olesiak-Banska, Joanna; Comby-Zerbino, Clothilde; Bertorelle, Franck; Dagany, Xavier; Bansal, Ashu K; Sajjad, Muhammad T; Samuel, Ifor D W; Sanader, Zeljka; Rozycka, Miroslawa; Wojtas, Magdalena; Matczyszyn, Katarzyna; Bonacic-Koutecky, Vlasta; Antoine, Rodolphe; Ozyhar, Andrzej; Samoc, Marek
2018-05-01
Thiolate-protected gold nanoclusters have recently attracted considerable attention due to their size-dependent luminescence characterized by a long lifetime and large Stokes shift. However, the optimization of nanocluster properties such as the luminescence quantum yield is still a challenge. We report here the transformation of Au25Capt18 (Capt labels captopril) nanoclusters occurring at low pH and yielding a product with a much increased luminescence quantum yield which we have identified as Au23Capt17. We applied a simple method of treatment with HCl to accomplish this transformation and we characterized the absorption and emission of the newly created ligated nanoclusters as well as their morphology. Based on DFT calculations we show which Au nanocluster size transformations can lead to highly luminescent species such as Au23Capt17.
Tonelli, Fernanda MP; Santos, Anderson K; Gomes, Katia N; Lorençon, Eudes; Guatimosim, Silvia; Ladeira, Luiz O; Resende, Rodrigo R
2012-01-01
In recent years, significant progress has been made in organ transplantation, surgical reconstruction, and the use of artificial prostheses to treat the loss or failure of an organ or bone tissue. In recent years, considerable attention has been given to carbon nanotubes and collagen composite materials and their applications in the field of tissue engineering due to their minimal foreign-body reactions, an intrinsic antibacterial nature, biocompatibility, biodegradability, and the ability to be molded into various geometries and forms such as porous structures, suitable for cell ingrowth, proliferation, and differentiation. Recently, grafted collagen and some other natural and synthetic polymers with carbon nanotubes have been incorporated to increase the mechanical strength of these composites. Carbon nanotube composites are thus emerging as potential materials for artificial bone and bone regeneration in tissue engineering. PMID:22923989
Pfefferbaum, Betty; North, Carol S; Flynn, Brian W; Norris, Fran H; DeMartino, Robert
2002-08-01
How did the 1995 Oklahoma City bombing differ from prior disasters and what implications did it have for disaster mental health services and service delivery? The federal disaster mental health approach in this country developed largely out of experiences with natural disasters. The 1995 Oklahoma City bombing differed in several important ways, including the large number of human casualties, higher rates of psychopathology, and an extended period of concern due to the criminal investigation and trials, which suggested the need to consider modifications in the program. Outreach was extensive, but psychiatric morbidity of direct victims was greater than that of victims of natural disasters, emphasizing the need for attention to the triage and referral process. Other concerns that warrant consideration include practices related to record keeping and program evaluation.
[Oppositional defiant disorder: aspects related to sex differences and informant].
Cardo, E; Meisel, V; García-Banda, G; Palmer, C; Riutort, L; Bernad, M; Servera, M
2009-02-27
Oppositional defiant disorder (ODD) is one of the most common externalizing disorders in childhood. ODD prevalence global rates vary from 2% to 16%. Along with conduct disorder and attention deficit disorder, ODD is one of the leading reasons for referral to neuropediatric and psychiatric services. Even though ODD has recognized clinical importance, key aspects of its conceptualization and prevalence in childhood and adolescence remain uncertain. We examine previous research findings of ODD prevalence and analyze sex differences and differences according to informants. ODD prevalence rates present high variability. A number of studies suggest that ODD is more common in boys than in girls. Nevertheless, some authors point that this sex differences may be due to methodological bias. We recommend the validation of an ODD scale that has into consideration the following aspects: level of the subject's development (age), gender and environment.
Reproduction beyond menopause: how old is too old for assisted reproductive technology?
Havemann, Dara L.; Phelps, John Y.
2010-01-01
Background Due to the recent media attention on postmenopausal women giving birth, there has been an increased scrutiny on the utility and safety of assisted reproductive technology in postmenopausal women. Objective The purpose of this commentary is to discuss the following: 1) the limitations and complications of ART in women of advanced reproductive age; 2) the balance between the welfare of the mother and that of the child; 3) the double standards of advanced reproductive age; and 4) the importance of financial and social support systems and preconception counseling with advanced reproductive age. Conclusion When providing in-vitro fertilization services to women of advanced reproductive age, special considerations must be given to ensure the welfare of mother and the child and that the principles of beneficence and nonmaleficence are guaranteed. PMID:20454846
[Ethylene glycol and propylene glycol ethers - Reproductive and developmental toxicity].
Starek-Świechowicz, Beata; Starek, Andrzej
2015-01-01
Both ethylene and propylene glycol alkyl ethers (EGAEs and PGAEs, respectively) are widely used, mainly as solvents, in industrial and household products. Some EGAEs demonstrate gonadotoxic, embriotoxic, fetotoxic and teratogenic effects in both humans and experimental animals. Due to the noxious impact of these ethers on reproduction and development of organisms EGAEs are replaced for considerably less toxic PGAEs. The data on the mechanisms of testicular, embriotoxic, fetotoxic and teratogenic effects of EGAEs are presented in this paper. Our particular attention was focused on the metabolism of some EGAEs and their organ-specific toxicities, apoptosis of spermatocytes associated with changes in the expression of various genes that code for oxidative stress factors, protein kinases and nuclear hormone receptors. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.
NASA Astrophysics Data System (ADS)
Xiao, Wenjiao
2016-06-01
This monograph book represents an important volume summarizing the present geological knowledge and understanding of the geodynamic evolution of large parts of the Central Asian Orogenic Belt (CAOB) or Altaids, which is one of the largest orogenic collages on Earth. The CAOB, like other major accretionary orogens, is a complex assembly of ancient microcontinents, arc terranes, accretionary wedges, fragments of oceanic volcanic islands (sea-mounts), oceanic plateaus, ophiolites, and shelf sediments from passive continental margins. The CAOB has caused much international attention due to its complicated architecture and considerably continental growth. However, after many years of investigations, some fundamental problems still remain controversial, such as the rate and volume of crustal growth, the origin of continental fragments, the detailed mechanism of accretion and collision, the role of terrane rotations during the orogeny, and the age and composition of the lower crust in Central Asia.
Secondary ion mass spectrometry: The application in the analysis of atmospheric particulate matter
DOE Office of Scientific and Technical Information (OSTI.GOV)
Huang, Di; Hua, Xin; Xiu, Guang-Li
Currently, considerable attention has been paid to atmospheric particulate matter (PM) investigation due to its importance in human health and global climate change. Surface characterization of PM is important since the chemical heterogeneity between the surface and bulk may vary its impact on the environment and human being. Secondary ion mass spectrometry (SIMS) is a surface technique with high surface sensitivity, capable of high spatial chemical imaging and depth profiling. Recent research shows that SIMS holds great potential in analyzing both surface and bulk chemical information of PM. In this review, we presented the working principal of SIMS in PMmore » characterization, summarized recent applications in PM analysis from different sources, discussed its advantages and limitations, and proposed the future development of this technique with a perspective in environmental sciences.« less
Recent Development in Optical Chemical Sensors Coupling with Flow Injection Analysis
Ojeda, Catalina Bosch; Rojas, Fuensanta Sánchez
2006-01-01
Optical techniques for chemical analysis are well established and sensors based on these techniques are now attracting considerable attention because of their importance in applications such as environmental monitoring, biomedical sensing, and industrial process control. On the other hand, flow injection analysis (FIA) is advisable for the rapid analysis of microliter volume samples and can be interfaced directly to the chemical process. The FIA has become a widespread automatic analytical method for more reasons; mainly due to the simplicity and low cost of the setups, their versatility, and ease of assembling. In this paper, an overview of flow injection determinations by using optical chemical sensors is provided, and instrumentation, sensor design, and applications are discussed. This work summarizes the most relevant manuscripts from 1980 to date referred to analysis using optical chemical sensors in FIA.
Aloe Vera for Tissue Engineering Applications.
Rahman, Shekh; Carter, Princeton; Bhattarai, Narayan
2017-02-14
Aloe vera, also referred as Aloe barbadensis Miller, is a succulent plant widely used for biomedical, pharmaceutical and cosmetic applications. Aloe vera has been used for thousands of years. However, recent significant advances have been made in the development of aloe vera for tissue engineering applications. Aloe vera has received considerable attention in tissue engineering due to its biodegradability, biocompatibility, and low toxicity properties. Aloe vera has been reported to have many biologically active components. The bioactive components of aloe vera have effective antibacterial, anti-inflammatory, antioxidant, and immune-modulatory effects that promote both tissue regeneration and growth. The aloe vera plant, its bioactive components, extraction and processing, and tissue engineering prospects are reviewed in this article. The use of aloe vera as tissue engineering scaffolds, gels, and films is discussed, with a special focus on electrospun nanofibers.
Experiments on a non-smoothly-forced oscillator
NASA Astrophysics Data System (ADS)
Virgin, Lawrence N.; George, Christopher; Kini, Ashwath
2015-12-01
This paper describes some typical behavior encountered in the response of a harmonically-excited mechanical system in which a severe nonlinearity occurs due to an impact. Although such systems have received considerable recent attention (most of it from a theoretical viewpoint), the system scrutinized in this paper also involves a discrete input of energy at the impact condition. That is, it is kicked when contact is made. One of the motivations for this work is related to a classic pinball machine in which a ball striking a bumper experiences a sudden impulse, introducing additional unpredictability to the motion of the ball. A one-dimensional analog of a pinball machine was the subject of a detailed mathematical study in Pring and Budd (2011), and the current paper details behavior obtained from a mechanical experiment and describes dynamics not observed in a conventional (passive) impact oscillator.
Shipyard Standards Program Development Guide
1992-10-01
Given the opportunity, designers will use designs that have worked for them in the past . Unfortunately, not all designers have the same experience base...standards formally approved by shipyard management? The subject of labor productivity standards has received considerable attention during the past decade. A...research into this consideration during the past decade. References [23], [24], [25], [26], and [27] have reported beneficial results obtained by getting the
Operational considerations to reduce solar array loads
NASA Technical Reports Server (NTRS)
Gerstenmaier, W.
1992-01-01
The key parameters associated with solar array plume loads are examined, and operational considerations aimed at minimizing the effect of the Shuttle plumes on the Space Station solar arrays are discussed. These include solar array pointing to reduce loads and restrictions on Shuttle piloting. Particular attention is given to the method used to obtain the forcing functions (thruster time firing histories) for solar array plume calculation.
Optimization of SMA layers in composite structures to enhance damping
NASA Astrophysics Data System (ADS)
Haghdoust, P.; Cinquemani, S.; Lecis, N.; Bassani, P.
2016-04-01
The performance of lightweight structures can be severely affected by vibration. New design concepts leading to lightweight, slender structural components can increase the vulnerability of the components to failure due to excessive vibration. The intelligent approach to address the problem would be the use of materials which are more capable in dissipating the energy due to their high value of loss factor. Among the different materials available to achieve damping, much attention has been attached to the use of shape memory alloys (SMAs) because of their unique microstructure, leading to good damping capacity. This work describes the design and optimization of a hybrid layered composite structure for the passive suppression of flexural vibrations in slender and light structures. Embedding the SMA layers in composite structure allows to combine different properties: the lightness of the base composite (e.g. fiber glass), the mechanical strength of the insert of metallic material and the relevant damping properties of SMA, in the martensitic phase. In particular, we put our attention on embedding the CuZnAl in the form of thin sheet in a layered composite made by glass fiber reinforced epoxy. By appropriately positioning of the SMA sheets so that they are subjected to the maximum curvature, the damping of the hybrid system can be considerably enhanced. Accordingly analytical method for evaluating the energy dissipation of the thin sheets with different shapes and patterns is developed and is followed by a shape optimization based on genetic algorithm. Eventually different configurations of the hybrid beam structure with different patterns of SMA layer are proposed and compared in the term of damping capacity.
An overview of attention deficits after paediatric traumatic brain injury.
Ginstfeldt, Tim; Emanuelson, Ingrid
2010-01-01
Attention could be categorized into sustained, selective, shifting, divided and attention span. The primary objective was to evaluate the type of attention deficits that occurs after paediatric traumatic brain injury. Keywords were used such as 'attention', 'child', 'traumatic', 'brain' and 'injury' on MEDLINE articles published in 1991-2009. Articles found through MEDLINE were manually cross-referenced. Out of the examined categorizes, divided and sustained attention seem to be the most vulnerably, frequently displaying deficits in the children with TBI. Attention span seemed to be the most resistant and the shifting and selective categories falling somewhere in between. Most of the recovery is expected within the first year post-injury, even if some individuals continue to improve for years, and deficits often persist into adulthood. The attention domains are not affected to the same extent by TBI and this should be taken into consideration when evaluating a child. The commonly used tests also seem to differ in how sensitive they are in detecting deficits. The definition of attention domains and TBI would benefit to be stricter and agreed upon, to further facilitate research and rehabilitation programmes.
Transport properties of β-FeSi2
NASA Astrophysics Data System (ADS)
Arushanov, Ernest; Lisunov, Konstantin G.
2015-07-01
The aim of this paper is to summarize considerable experimental efforts undertaken within the last decades in the investigations of transport properties of β-FeSi2. The β-FeSi2 compound is the most investigated among a family of semiconducting silicides. This material has received considerable attention as an attractive material for optoelectronic, photonics, photovoltaics and thermoelectric applications. Previous reviews of the transport properties of β-FeSi2 have been given by Lange and Ivanenko et al. about 15 years ago. The Hall effect, the conductivity, the mobility and the magnetoresistance data are presented. Main attention is paid to the discussion of the impurity (defect) band conductivity, the anomalous Hall effect, the scattering mechanisms of charge carriers, as well as to the hopping conduction and the magnetoresistance.
[Considering human peculiarities in attention to health care through dialogue and assistance].
Pereira, Adriana Dall'Asta; de Freitas, Hilda Maria Barbosa; Ferreira, Carla Lizandra de Lima; Marchiori, Mara Regina Caino Teixeira; Souza, Martha Helena Teixeira; Backes, Dirce Stein
2010-03-01
The aim of this qualitative exploratory research is to understand how health workers relate to the main object of their work--the user--both subject and author of his/her life history. Eleven nursing practitioners from a Basic Health Unit participated in a semi-structured instrument, in March and April, 2008. The speeches revealed two converging themes: (1) Consideration of human peculiarities in attention to health care; and (2) dialogue and assistance as interactive possibilities. We found that the attention to health care is broadening the debates over valuing human peculiarities through dialogue and assistance as interactive possibilities.
More attention when speaking: does it help or does it hurt?
Nozari, Nazbanou; Thompson-Schill, Sharon L
2013-11-01
Paying selective attention to a word in a multi-word utterance results in a decreased probability of error on that word (benefit), but an increased probability of error on the other words (cost). We ask whether excitation of the prefrontal cortex helps or hurts this cost. One hypothesis (the resource hypothesis) predicts a decrease in the cost due to the deployment of more attentional resources, while another (the focus hypothesis) predicts even greater costs due to further fine-tuning of selective attention. Our results are more consistent with the focus hypothesis: prefrontal stimulation caused a reliable increase in the benefit and a marginal increase in the cost of selective attention. To ensure that the effects are due to changes to the prefrontal cortex, we provide two checks: We show that the pattern of results is quite different if, instead, the primary motor cortex is stimulated. We also show that the stimulation-related benefits in the verbal task correlate with the stimulation-related benefits in an N-back task, which is known to tap into a prefrontal function. Our results shed light on how selective attention affects language production, and more generally, on how selective attention affects production of a sequence over time. Copyright © 2013 Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
Dutton, Eileen; Salazar, Chris
1998-01-01
Discusses ways of preparing school-building roofs for the winter season by paying attention to common problem areas. Also highlights the use of white elastomeric roof coatings, their benefits, and considerations when applying them. (GR)
Does visual attention drive the dynamics of bistable perception?
Dieter, Kevin C.; Brascamp, Jan; Tadin, Duje; Blake, Randolph
2016-01-01
How does attention interact with incoming sensory information to determine what we perceive? One domain in which this question has received serious consideration is that of bistable perception: a captivating class of phenomena that involves fluctuating visual experience in the face of physically unchanging sensory input. Here, some investigations have yielded support for the idea that attention alone determines what is seen, while others have implicated entirely attention-independent processes in driving alternations during bistable perception. We review the body of literature addressing this divide and conclude that in fact both sides are correct – depending on the form of bistable perception being considered. Converging evidence suggests that visual attention is required for alternations in the type of bistable perception called binocular rivalry, while alternations during other types of bistable perception appear to continue without requiring attention. We discuss some implications of this differential effect of attention for our understanding of the mechanisms underlying bistable perception, and examine how these mechanisms operate during our everyday visual experiences. PMID:27230785
Does visual attention drive the dynamics of bistable perception?
Dieter, Kevin C; Brascamp, Jan; Tadin, Duje; Blake, Randolph
2016-10-01
How does attention interact with incoming sensory information to determine what we perceive? One domain in which this question has received serious consideration is that of bistable perception: a captivating class of phenomena that involves fluctuating visual experience in the face of physically unchanging sensory input. Here, some investigations have yielded support for the idea that attention alone determines what is seen, while others have implicated entirely attention-independent processes in driving alternations during bistable perception. We review the body of literature addressing this divide and conclude that in fact both sides are correct-depending on the form of bistable perception being considered. Converging evidence suggests that visual attention is required for alternations in the type of bistable perception called binocular rivalry, while alternations during other types of bistable perception appear to continue without requiring attention. We discuss some implications of this differential effect of attention for our understanding of the mechanisms underlying bistable perception, and examine how these mechanisms operate during our everyday visual experiences.
Rabies Exposure: When Should I Seek Medical Attention?
... Rabies and Kids! When should I seek medical attention? Language: English Spanish Recommend on Facebook Tweet Share ... with soap and water. See your doctor for attention for any trauma due to an animal attack ...
Age-related slowing: perceptuomotor, decision, or attention decline?
Godefroy, Olivier; Roussel, Martine; Despretz, Pascal; Quaglino, Véronique; Boucart, Muriel
2010-04-01
Age-related slowing is well documented but its origin remains unclear. A first validation study (Study 1) performed in 46 participants examined the effect of attention allocation (manipulated through a dual task) on various portions of individual simple reaction time (SRT) distribution (minimum, centile 5, centile 50, and centile 95 RTs). It showed that attention 'deprivation' due to a secondary task is not uniform throughout the distribution but impaired mainly the ability to produce a large number of fast responses. Study 2 investigated in 88 healthy participants age-related slowing of perceptual, motor, decision, and attentional processes using SRT and choice reaction time (CRT), finger tapping, and visual inspection time tests. It showed that the majority of SRT slowing after the age of 40 is due to lengthening of centile 5 RT, suggesting perceptuomotor slowing, an interpretation supported by longer visual inspection time and lower tapping frequency. After 60 years, SRT lengthening was due to a further lengthening of the centile 5-centile 50 SRT index, suggesting the participation of attentional decline. These findings support the hypothesis that age-related slowing in simple repetitive tasks is mainly related to slowing at the stage of perceptuomotor processes, and after 60 years, to additional decline of attention.
Meditation-induced states predict attentional control over time.
Colzato, Lorenza S; Sellaro, Roberta; Samara, Iliana; Baas, Matthijs; Hommel, Bernhard
2015-12-01
Meditation is becoming an increasingly popular topic for scientific research and various effects of extensive meditation practice (ranging from weeks to several years) on cognitive processes have been demonstrated. Here we show that extensive practice may not be necessary to achieve those effects. Healthy adult non-meditators underwent a brief single session of either focused attention meditation (FAM), which is assumed to increase top-down control, or open monitoring meditation (OMM), which is assumed to weaken top-down control, before performing an Attentional Blink (AB) task - which assesses the efficiency of allocating attention over time. The size of the AB was considerably smaller after OMM than after FAM, which suggests that engaging in meditation immediately creates a cognitive-control state that has a specific impact on how people allocate their attention over time. Copyright © 2015 Elsevier Inc. All rights reserved.
Code of Federal Regulations, 2013 CFR
2013-01-01
... processing any Application for approval, that the Borrower agree to pay the costs of a Consultant hired to... conditions of Consultant Contracts. The Borrower may bring considerations to the attention of the government...
Code of Federal Regulations, 2014 CFR
2014-01-01
... processing any Application for approval, that the Borrower agree to pay the costs of a Consultant hired to... conditions of Consultant Contracts. The Borrower may bring considerations to the attention of the government...
Code of Federal Regulations, 2011 CFR
2011-01-01
... processing any Application for approval, that the Borrower agree to pay the costs of a Consultant hired to... conditions of Consultant Contracts. The Borrower may bring considerations to the attention of the government...
Code of Federal Regulations, 2012 CFR
2012-01-01
... processing any Application for approval, that the Borrower agree to pay the costs of a Consultant hired to... conditions of Consultant Contracts. The Borrower may bring considerations to the attention of the government...
Code of Federal Regulations, 2010 CFR
2010-01-01
... processing any Application for approval, that the Borrower agree to pay the costs of a Consultant hired to... conditions of Consultant Contracts. The Borrower may bring considerations to the attention of the government...
ERIC Educational Resources Information Center
Debreli, Emre
2016-01-01
The study of L1 (first language) use in L2 (second language) classrooms has long received attention in the literature. Despite the considerable amount of research that has been conducted on the phenomenon, the focus has often been on the advantages and disadvantages. Considerably, less research has been conducted regarding the non-native L2…
Decoding facial expressions based on face-selective and motion-sensitive areas.
Liang, Yin; Liu, Baolin; Xu, Junhai; Zhang, Gaoyan; Li, Xianglin; Wang, Peiyuan; Wang, Bin
2017-06-01
Humans can easily recognize others' facial expressions. Among the brain substrates that enable this ability, considerable attention has been paid to face-selective areas; in contrast, whether motion-sensitive areas, which clearly exhibit sensitivity to facial movements, are involved in facial expression recognition remained unclear. The present functional magnetic resonance imaging (fMRI) study used multi-voxel pattern analysis (MVPA) to explore facial expression decoding in both face-selective and motion-sensitive areas. In a block design experiment, participants viewed facial expressions of six basic emotions (anger, disgust, fear, joy, sadness, and surprise) in images, videos, and eyes-obscured videos. Due to the use of multiple stimulus types, the impacts of facial motion and eye-related information on facial expression decoding were also examined. It was found that motion-sensitive areas showed significant responses to emotional expressions and that dynamic expressions could be successfully decoded in both face-selective and motion-sensitive areas. Compared with static stimuli, dynamic expressions elicited consistently higher neural responses and decoding performance in all regions. A significant decrease in both activation and decoding accuracy due to the absence of eye-related information was also observed. Overall, the findings showed that emotional expressions are represented in motion-sensitive areas in addition to conventional face-selective areas, suggesting that motion-sensitive regions may also effectively contribute to facial expression recognition. The results also suggested that facial motion and eye-related information played important roles by carrying considerable expression information that could facilitate facial expression recognition. Hum Brain Mapp 38:3113-3125, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.
NASA Astrophysics Data System (ADS)
Ju, Yaping; Zhang, Chuhua
2016-03-01
Blade fouling has been proved to be a great threat to compressor performance in operating stage. The current researches on fouling-induced performance degradations of centrifugal compressors are based mainly on simplified roughness models without taking into account the realistic factors such as spatial non-uniformity and randomness of the fouling-induced surface roughness. Moreover, little attention has been paid to the robust design optimization of centrifugal compressor impellers with considerations of blade fouling. In this paper, a multi-objective robust design optimization method is developed for centrifugal impellers under surface roughness uncertainties due to blade fouling. A three-dimensional surface roughness map is proposed to describe the nonuniformity and randomness of realistic fouling accumulations on blades. To lower computational cost in robust design optimization, the support vector regression (SVR) metamodel is combined with the Monte Carlo simulation (MCS) method to conduct the uncertainty analysis of fouled impeller performance. The analyzed results show that the critical fouled region associated with impeller performance degradations lies at the leading edge of blade tip. The SVR metamodel has been proved to be an efficient and accurate means in the detection of impeller performance variations caused by roughness uncertainties. After design optimization, the robust optimal design is found to be more efficient and less sensitive to fouling uncertainties while maintaining good impeller performance in the clean condition. This research proposes a systematic design optimization method for centrifugal compressors with considerations of blade fouling, providing a practical guidance to the design of advanced centrifugal compressors.
Effect of air pollution on pediatric respiratory emergency room visits and hospital admissions.
Farhat, S C L; Paulo, R L P; Shimoda, T M; Conceição, G M S; Lin, C A; Braga, A L F; Warth, M P N; Saldiva, P H N
2005-02-01
In order to assess the effect of air pollution on pediatric respiratory morbidity, we carried out a time series study using daily levels of PM10, SO2, NO2, ozone, and CO and daily numbers of pediatric respiratory emergency room visits and hospital admissions at the Children's Institute of the University of Sao Paulo Medical School, from August 1996 to August 1997. In this period there were 43,635 hospital emergency room visits, 4534 of which were due to lower respiratory tract disease. The total number of hospital admissions was 6785, 1021 of which were due to lower respiratory tract infectious and/or obstructive diseases. The three health end-points under investigation were the daily number of emergency room visits due to lower respiratory tract diseases, hospital admissions due to pneumonia, and hospital admissions due to asthma or bronchiolitis. Generalized additive Poisson regression models were fitted, controlling for smooth functions of time, temperature and humidity, and an indicator of weekdays. NO2 was positively associated with all outcomes. Interquartile range increases (65.04 microg/m3) in NO2 moving averages were associated with an 18.4% increase (95% confidence interval, 95% CI = 12.5-24.3) in emergency room visits due to lower respiratory tract diseases (4-day moving average), a 17.6% increase (95% CI = 3.3-32.7) in hospital admissions due to pneumonia or bronchopneumonia (3-day moving average), and a 31.4% increase (95% CI = 7.2-55.7) in hospital admissions due to asthma or bronchiolitis (2-day moving average). The study showed that air pollution considerably affects children's respiratory morbidity, deserving attention from the health authorities.
Environmental Assessment. Moanalua Shopping Center Redevelopment Oahu, Hawaii
2004-08-01
redevelop the approximately 15-acre MSC site as in-kind consideration for the fair market rent which would be due under a 40-year lease of the...the existing approximately 15-acre (6-hectare) MSC site as in-kind consideration for the fair market rent which would be due under a 40-year lease of...would redevelop the existing MSC site as in-kind consideration for the fair market rent which would be due under a 40-year lease of the properties
Huss, Michael; Völp, Andreas; Stauss-Grabo, Manuela
2010-09-24
Polyunsaturated fatty acids are essential nutrients for humans. They are structural and functional components of cell membranes and pre-stages of the hormonally and immunologically active eicosanoids. Recent discoveries have shown that the long-chained omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) also play an important role in the central nervous system. They are essential for normal brain functioning including attention and other neuropsychological skills. In our large observational study we monitored 810 children from 5 to 12 years of age referred for medical help and recommended for consuming polyunsaturated fatty acids (PUFA) in combination with zinc and magnesium by a physician over a period of at least 3 months. The food supplement ESPRICO® (further on referred to as the food supplement) is developed on the basis of current nutritional science and containing a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc. Study objective was to evaluate the nutritional effects of the PUFA-zinc-magnesium combination on symptoms of attention deficit, impulsivity, and hyperactivity as well as on emotional problems and sleep related parameters. Assessment was performed by internationally standardised evaluation scales, i.e. SNAP-IV and SDQ. Tolerance (adverse events) and acceptance (compliance) of the dietary therapy were documented. After 12 weeks of consumption of a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc most subjects showed a considerable reduction in symptoms of attention deficit and hyperactivity/impulsivity assessed by SNAP-IV. Further, the assessment by SDQ revealed fewer emotional problems at the end of the study period compared to baseline and also sleeping disorders. Mainly problems to fall asleep, decreased during the 12 week nutritional therapy. Regarding safety, no serious adverse events occurred. A total of 16 adverse events with a possible causal relationship to the study medication were reported by 14 children (1.7%) and only 5.2% of the children discontinued the study due to acceptance problems. Continuation of consumption of the food supplement was recommended by the paediatricians for 61.1% of the children. Our results suggest a beneficial effect of a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc consumption on attentional, behavioural, and emotional problems of children and adolescents. Thus, considering the behavioural benefit in combination with the low risk due to a good safety profile, the dietary supplementation with PUFA in combination with zinc and magnesium can be recommended.
2004 Sexual Harassment Survey of Reserve Component Members
2005-03-01
considerable media attention. In the ment and fraternization problems were occurring at spring of 1990, a female Midshipman at the Naval Naval...General (DoD IG) team’s incident of sexual harassment drew wide investigation was undertaken at the request of the media attention; and, in 1994, the...EO) programs and instituted major hearings was widely promulgated in the media . changes to its EO policies and programs. Shortly after the hearings
Ionic Liquids in Selective Oxidation: Catalysts and Solvents.
Dai, Chengna; Zhang, Jie; Huang, Chongpin; Lei, Zhigang
2017-05-24
Selective oxidation has an important role in environmental and green chemistry (e.g., oxidative desulfurization of fuels and oxidative removal of mercury) as well as chemicals and intermediates chemistry to obtain high-value-added special products (e.g., organic sulfoxides and sulfones, aldehydes, ketones, carboxylic acids, epoxides, esters, and lactones). Due to their unique physical properties such as the nonvolatility, thermal stability, nonexplosion, high polarity, and temperature-dependent miscibility with water, ionic liquids (ILs) have attracted considerable attention as reaction solvents and media for selective oxidations and are considered as green alternatives to volatile organic solvents. Moreover, for easy separation and recyclable utilization, IL catalysts have attracted unprecedented attention as "biphasic catalyst" or "immobilized catalyst" by immobilizing metal- or nonmetal-containing ILs onto mineral or polymer supports to combine the unique properties of ILs (chemical and thermal stability, capacity for extraction of polar substrates and reaction products) with the extended surface of the supports. This review highlights the most recent outcomes on ILs in several important typical oxidation reactions. The contents are arranged in the series of oxidation of sulfides, oxidation of alcohols, epoxidation of alkenes, Baeyer-Villiger oxidation reaction, oxidation of alkanes, and oxidation of other compounds step by step involving ILs as solvents, catalysts, reagents, or their combinations.
NASA Astrophysics Data System (ADS)
Susmitha, M.; Sharan, P.; Jyothi, P. N.
2016-09-01
Friction between work piece-cutting tool-chip generates heat in the machining zone. The heat generated reduces the tool life, increases surface roughness and decreases the dimensional sensitiveness of work material. This can be overcome by using cutting fluids during machining. They are used to provide lubrication and cooling effects between cutting tool and work piece and cutting tool and chip during machining operation. As a result, important benefits would be achieved such longer tool life, easy chip flow and higher machining quality in the machining processes. Non-edible vegetable oils have received considerable research attention in the last decades owing to their remarkable improved tribological characteristics and due to increasing attention to environmental issues, have driven the lubricant industry toward eco friendly products from renewable sources. In the present work, different non-edible vegetable oils are used as cutting fluid during drilling of Mild steel work piece. Non-edible vegetable oils, used are Karanja oil (Honge), Neem oil and blend of these two oils. The effect of these cutting fluids on chip formation, surface roughness and cutting force are investigated and the results obtained are compared with results obtained with petroleum based cutting fluids and dry conditions.
A Review of Injectable Polymeric Hydrogel Systems for Application in Bone Tissue Engineering.
Kondiah, Pariksha J; Choonara, Yahya E; Kondiah, Pierre P D; Marimuthu, Thashree; Kumar, Pradeep; du Toit, Lisa C; Pillay, Viness
2016-11-21
Biodegradable, stimuli-responsive polymers are essential platforms in the field of drug delivery and injectable biomaterials for application of bone tissue engineering. Various thermo-responsive hydrogels display water-based homogenous properties to encapsulate, manipulate and transfer its contents to the surrounding tissue, in the least invasive manner. The success of bioengineered injectable tissue modified delivery systems depends significantly on their chemical, physical and biological properties. Irrespective of shape and defect geometry, injectable therapy has an unparalleled advantage in which intricate therapy sites can be effortlessly targeted with minimally invasive procedures. Using material testing, it was found that properties of stimuli-responsive hydrogel systems enhance cellular responses and cell distribution at any site prior to the transitional phase leading to gelation. The substantially hydrated nature allows significant simulation of the extracellular matrix (ECM), due to its similar structural properties. Significant current research strategies have been identified and reported to date by various institutions, with particular attention to thermo-responsive hydrogel delivery systems, and their pertinent focus for bone tissue engineering. Research on future perspective studies which have been proposed for evaluation, have also been reported in this review, directing considerable attention to the modification of delivering natural and synthetic polymers, to improve their biocompatibility and mechanical properties.
Epistemological and ethical assessment of obesity bias in industrialized countries
2011-01-01
Bernard Lonergan's cognitive theory challenges us to raise questions about both the cognitive process through which obesity is perceived as a behaviour change issue and the objectivity of such a moral judgment. Lonergan's theory provides the theoretical tools to affirm that anti-fat discrimination, in the United States of America and in many industrialized countries, is the result of both a group bias that resists insights into the good of other groups and a general bias of anti-intellectualism that tends to set common sense against insights that require any thorough scientific analyses. While general bias diverts the public's attention away from the true aetiology of obesity, group bias sustains an anti-fat culture that subtly legitimates discriminatory practices and policies against obese people. Although anti-discrimination laws may seem to be a reasonable way of protecting obese and overweight individuals from discrimination, obesity bias can be best addressed by reframing the obesity debate from an environmental perspective from which tools and strategies to address both the social and individual determinants of obesity can be developed. Attention should not be concentrated on individuals' behaviour as it is related to lifestyle choices, without giving due consideration to the all-encompassing constraining factors which challenge the social and rational blindness of obesity bias. PMID:22177365
A comprehensive review of electrocoagulation for water treatment: Potentials and challenges.
Moussa, Dina T; El-Naas, Muftah H; Nasser, Mustafa; Al-Marri, Mohammed J
2017-01-15
Electrocoagulation is an effective electrochemical approach for the treatment of different types of contaminated water and has received considerable attention in recent years due its high efficiency in dealing with numerous stubborn pollutants. It has been successful in dealing with organic and inorganic contaminants with negligible or almost no generation of by-product wastes. During the past decade, vast amount of research has been devoted to utilizing electrocoagulation for the treatment of several types of wastewater, ranging from polluted groundwater to highly contaminated refinery wastewater. This paper offers a comprehensive review of recent literature that has been dedicated to utilizing electrocoagulation for water treatment, focusing on current successes on specific applications in water and wastewater treatment, as well as potentials for future applications. The paper examines such aspects as theory, potential applications, current challenges, recent developments as well as economical concerns associated with the technology. Most of the recent EC research has been focusing on pollutant-specific evaluation without paying attention to cell design, process modeling or industrial applications. This review attempts to highlight the main achievements in the area and outlines the major shortcomings with recommendations for promising research options that can enhance the technology and broaden its range of applications. Copyright © 2016 Elsevier Ltd. All rights reserved.
Epistemological and ethical assessment of obesity bias in industrialized countries.
Azétsop, Jacquineau; Joy, Tisha R
2011-12-16
Bernard Lonergan's cognitive theory challenges us to raise questions about both the cognitive process through which obesity is perceived as a behaviour change issue and the objectivity of such a moral judgment. Lonergan's theory provides the theoretical tools to affirm that anti-fat discrimination, in the United States of America and in many industrialized countries, is the result of both a group bias that resists insights into the good of other groups and a general bias of anti-intellectualism that tends to set common sense against insights that require any thorough scientific analyses. While general bias diverts the public's attention away from the true aetiology of obesity, group bias sustains an anti-fat culture that subtly legitimates discriminatory practices and policies against obese people. Although anti-discrimination laws may seem to be a reasonable way of protecting obese and overweight individuals from discrimination, obesity bias can be best addressed by reframing the obesity debate from an environmental perspective from which tools and strategies to address both the social and individual determinants of obesity can be developed. Attention should not be concentrated on individuals' behaviour as it is related to lifestyle choices, without giving due consideration to the all-encompassing constraining factors which challenge the social and rational blindness of obesity bias.
NASA Astrophysics Data System (ADS)
Smyth, Ciarán A.; Mehigan, Sam; Rakovich, Yury P.; Bell, Steven E. J.; McCabe, Eithne M.
2011-07-01
Optical techniques toward the realization of sensitive and selective biosensing platforms have received considerable attention in recent times. Techniques based on interferometry, surface plasmon resonance, and waveguides have all proved popular, while spectroscopy in particular offers much potential. Raman spectroscopy is an information-rich technique in which the vibrational frequencies reveal much about the structure of a compound, but it is a weak process and offers poor sensitivity. In response to this problem, surface-enhanced Raman scattering (SERS) has received much attention, due to significant increases in sensitivity instigated by bringing the sample into contact with an enhancing substrate. Here we discuss a facile and rapid technique for the detection of pterins using SERS-active colloidal silver suspensions. Pterins are a family of biological compounds that are employed in nature in color pigmentation and as facilitators in metabolic pathways. In this work, small volumes of xanthopterin, isoxanthopterin, and 7,8-dihydrobiopterin have been examined while adsorbed to silver colloids. Limits of detection have been examined for both xanthopterin and isoxanthopterin using a 10-s exposure to a 12 mW 532 nm laser, which, while showing a trade-off between scan time and signal intensity, still provides the opportunity for the investigation of simultaneous detection of both pterins in solution.
The Psychological Benefits from Reconceptualizing Music-Making as Mindfulness Practice.
Steinfeld, Matthew; Brewer, Judson
2015-06-01
While the music psychology and education literatures have devoted considerable attention to how musical instrumentalists practice their instruments, less formal scholarly attention has been given in consideration of what it means to maintain a musical "practice" over time and across context. In this paper, the practice of mindfulness meditation is used as heuristic, arguing for a view of mindfulness meditation as a formalized de-specialization of the infinite number of other activities with which people can achieve mindfulness. Sitting meditation, requiring of one to observe the contents of their mind unmediated, can serve as a useful model for the musician in understanding the phenomenology of the music-making process and the "flow" states that can result from an embodied musical practice. Finally, reconceptualizing music-making as a mindfulness practice is considered with psychological and pedagogical implications relevant for developing musicians.
Mishra, Amaresh; Fischer, Markus K R; Bäuerle, Peter
2009-01-01
Dye-sensitized solar cells (DSSC) have attracted considerable attention in recent years as they offer the possibility of low-cost conversion of photovoltaic energy. This Review focuses on recent advances in molecular design and technological aspects of metal-free organic dyes for applications in dye-sensitized solar cells. Special attention has been paid to the design principles of these dyes and on the effect of various electrolyte systems. Cosensitization, an emerging technique to extend the absorption range, is also discussed as a way to improve the performance of the device. In addition, we report on inverted dyes for photocathodes, which constitutes a relatively new approach for the production of tandem cells. Special consideration has been paid to the correlation between the molecular structure and physical properties to their performance in DSSCs.
Medical Evaluation Before Operation
Elliot, Diane L.; Linz, Douglas H.; Kane, Joseph A.
1982-01-01
Surgical outcome can be optimized by anticipation and prevention of medical complications. General considerations that apply to all patients include evaluation for coagulation disorders, prior anesthetic complications and drug history. Evaluation for organ-specific risk factors allows identification of patients at high surgical risk, minimization of risk and anticipation of postoperative complications. Review of the recent literature and a practical guide to therapy is presented for the major medical considerations before surgical procedures: cardiac disease, hypertension, pulmonary disease, endocrine considerations and hepatic disease. Attention to these areas and communication among internists, anesthesiologists and surgeons should provide optimal treatment of surgical patients with medical disease. PMID:7179956
Photogrammetry and optical methods in structural dynamics - A review
NASA Astrophysics Data System (ADS)
Baqersad, Javad; Poozesh, Peyman; Niezrecki, Christopher; Avitabile, Peter
2017-03-01
In the last few decades, there has been a surge of research in the area of non-contact measurement techniques. Photogrammetry has received considerable attention due to its ability to achieve full-field measurement and its robustness to work in testing environments and on testing articles in which using other measurement techniques may not be practical. More recently, researchers have used this technique to study transient phenomena and to perform measurements on vibrating structures. The current paper reviews the most current trends in the photogrammetry technique (point tracking, digital image correlation, and target-less approaches) and compares the applications of photogrammetry to other measurement techniques used in structural dynamics (e.g. laser Doppler vibrometry and interferometry techniques). The paper does not present the theoretical background of the optical techniques, but instead presents the general principles of each approach and highlights the novel structural dynamic measurement concepts and applications that are enhanced by utilizing optical techniques.
Consideration of IP Telephony Quality on the IEEE802.11a Wireless LAN
NASA Astrophysics Data System (ADS)
Miyashita, Michifumi; Takamatsu, Hideyuki; Kurono, Masahiro
Recently, IP telephony services in wired network are started, and paid attention for its charge-free nature due to IP technology. On the other hand, the Hot-Spot service, which provides one to access the Internet at the public space such as cafe, using the IEEE wireless LAN has been evolved, and it is expected that the IP telephony service on the Hot-Spot network will be developed. However, the IP telephony quality on the IEEE802.11a wireless LAN has not been fully studied yet. In this paper, we discuss about the quality of IP telephony service on the IEEE802.11a wireless LAN from the aspect of R-value, and show ability to improve the IP telephony quality on the Hot-Spot network employing PLC function defined in the ITU-T Recommendation G.711 Appendix I.
Can we always ignore ship-generated food waste?
Polglaze, John
2003-01-01
Considerable quantities of food waste can be generated at a rapid rate in ships, particularly those with large numbers of people onboard. By virtue of the amounts involved and its nature, food waste is potentially the most difficult to manage component of a ship's garbage stream, however, in most sea areas it may be dealt with by the simple expedient of direct discharge to sea. As a consequence, only minimal attention is paid to food waste management by many ship and port operators and advisory bodies, and there is a paucity of information in the available literature. The determination that management of ships' food waste is inconsequential is, however, incorrect in many circumstances. Disposal to sea is not always possible due to restrictions imposed by MARPOL 73/78 and other marine pollution control instruments. Effective management of food waste can be critical for ships that operate in areas where disposal is restricted or totally prohibited.
Science, technology, and application of THz air photonics
NASA Astrophysics Data System (ADS)
Lu, X. F.; Clough, B.; Ho, I.-C.; Kaur, G.; Liu, J.; Karpowicz, N.; Dai, J. M.; Zhang, X.-C.
2010-11-01
The significant scientific and technological potential of terahertz (THz) wave sensing and imaging has been attracted considerable attention within many fields of research. However, the development of remote, broadband THz wave sensing technology is lagging behind the compelling needs that exist in the areas of astronomy, global environmental monitoring, and homeland security. This is due to the challenge posed by high absorption of ambient moisture in the THz range. Although various time-domain THz detection techniques have recently been demonstrated, the requirement for an on-site bias or forward collection of the optical signal inevitably prohibits their applications for remote sensing. The objective of this paper is to report updated THz air-plasma technology to meet this great challenge of remote sensing. A focused optical pulse (mJ pulse energy and femtosecond pulse duration) in gas creates a plasma, which can serve to generate intense, broadband, and directional THz waves in the far field.
Sentiment Analysis Using Common-Sense and Context Information
Mittal, Namita; Bansal, Pooja; Garg, Sonal
2015-01-01
Sentiment analysis research has been increasing tremendously in recent times due to the wide range of business and social applications. Sentiment analysis from unstructured natural language text has recently received considerable attention from the research community. In this paper, we propose a novel sentiment analysis model based on common-sense knowledge extracted from ConceptNet based ontology and context information. ConceptNet based ontology is used to determine the domain specific concepts which in turn produced the domain specific important features. Further, the polarities of the extracted concepts are determined using the contextual polarity lexicon which we developed by considering the context information of a word. Finally, semantic orientations of domain specific features of the review document are aggregated based on the importance of a feature with respect to the domain. The importance of the feature is determined by the depth of the feature in the ontology. Experimental results show the effectiveness of the proposed methods. PMID:25866505
Song, Kenan; Zhang, Yiying; Meng, Jiangsha; Green, Emily C.; Tajaddod, Navid; Li, Heng; Minus, Marilyn L.
2013-01-01
Among the many potential applications of carbon nanotubes (CNT), its usage to strengthen polymers has been paid considerable attention due to the exceptional stiffness, excellent strength, and the low density of CNT. This has provided numerous opportunities for the invention of new material systems for applications requiring high strength and high modulus. Precise control over processing factors, including preserving intact CNT structure, uniform dispersion of CNT within the polymer matrix, effective filler–matrix interfacial interactions, and alignment/orientation of polymer chains/CNT, contribute to the composite fibers’ superior properties. For this reason, fabrication methods play an important role in determining the composite fibers’ microstructure and ultimate mechanical behavior. The current state-of-the-art polymer/CNT high-performance composite fibers, especially in regards to processing–structure–performance, are reviewed in this contribution. Future needs for material by design approaches for processing these nano-composite systems are also discussed. PMID:28809290
Need total sulfur content? Use chemiluminescence
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kubala, S.W.; Campbell, D.N.; DiSanzo, F.P.
Regulations issued by the United States Environmental Protection Agency require petroleum refineries to reduce or control the amount of total sulfur present in their refined products. These legislative requirements have led many refineries to search for online instrumentation that can produce accurate and repeatable total sulfur measurements within allowed levels. Several analytical methods currently exist to measure total sulfur content. They include X-ray fluorescence (XRF), microcoulometry, lead acetate tape, and pyrofluorescence techniques. Sulfur-specific chemiluminescence detection (SSCD) has recently received much attention due to its linearity, selectivity, sensitivity, and equimolar response. However, its use has been largely confined to the areamore » of gas chromatography. This article focuses on the special design considerations and analytical utility of an SSCD system developed to determine total sulfur content in gasoline. The system exhibits excellent linearity and selectivity, the ability to detect low minimum levels, and an equimolar response to various sulfur compounds. 2 figs., 2 tabs.« less
Chen, Linfeng; Shi, Xiaodi; Li, Mingzhu; Hu, Junping; Sun, Shufeng; Su, Bin; Wen, Yongqiang; Han, Dong; Jiang, Lei; Song, Yanlin
2015-01-01
Fireflies have drawn considerable attention for thousands of years due to their highly efficient bioluminescence, which is important for fundamental research and photonic applications. However, there are few reports on the reflector layer (RL) of firefly lantern, which contributes to the bright luminescence. Here we presented the detailed microstructure of the RL consisting of random hollow granules, which had high reflectance in the range from 450 nm to 800 nm. Inspired by the firefly lantern, artificial films with high reflectance in the visible region were fabricated using hollow silica microparticles mimicking the structure of the RL. Additionally, the bioinspired structures provided an efficient RL for the chemiluminescence system and could substantially enhance the initial chemiluminescence intensity. The work not only provides new insight into the bright bioluminescence of fireflies, but also is importance for the design of photonic materials for theranostics, detection, and imaging. PMID:26264643
Social Categorization on Perception Bias in the Practice of Microteaching
NASA Astrophysics Data System (ADS)
Hong, Jon-Chao; Hwang, Ming-Yueh; Lu, Chow-Chin; Tsai, Chi-Ruei
2017-02-01
Microteaching has gained considerable attention for its effectiveness in rapid and contextual training in professional development programs. However, the interpretive quality of the teaching demonstration and peer feedback may influence individuals' attribution and self-correction, leading to ineffective learning. In this study, a microteaching workshop in a professional development program for 78 elementary school science teachers was investigated. The results showed that the effectiveness of microteaching was negatively affected by participants' perception bias due to social categorization. Moreover, it was indicated that the participants' perception of the in-group and out-group, classified by the degree of the individuals' science knowledge, fostered social categorization. Participants tended to experience perception conflicts caused by their inability to see personal faults, and a typical perception bias of "seeing one's own strengths and seeing others' shortcomings" was more frequently recognized in the out-group. These results converge to highlight the importance of social categorization in perception bias relevant to microteaching.
A review on palm oil mill biogas plant wastewater treatment using coagulation-ozonation
NASA Astrophysics Data System (ADS)
Dexter, Z. D.; Joseph, C. G.; Zahrim, A. Y.
2016-06-01
Palm oil mill effluent (POME) generated from the palm oil industry is highly polluted and requires urgent attention for treatment due to its high organic content. Biogas plant containing anaerobic digester is capable to treat the high organic content of the POME while generating valuable biogas at the same time. This green energy from POME is environmental-friendly but the wastewater produced is still highly polluted and blackish in colour. Therefore a novel concept of combining coagulation with ozonation treatment is proposed to treat pollution of this nature. Several parameters should be taken under consideration in order to ensure the effectiveness of the hybrid treatment including ozone dosage, ozone contact time, pH of the water or wastewater, coagulant dosage, and mixing and settling time. This review paper will elucidate the importance of hybrid coagulation-ozonation treatment in producing a clear treated wastewater which is known as the main challenge in palm oil industry
Mushroom Lectins: Specificity, Structure and Bioactivity Relevant to Human Disease
Hassan, Mohamed Ali Abol; Rouf, Razina; Tiralongo, Evelin; May, Tom W.; Tiralongo, Joe
2015-01-01
Lectins are non-immunoglobulin proteins that bind diverse sugar structures with a high degree of selectivity. Lectins play crucial role in various biological processes such as cellular signaling, scavenging of glycoproteins from the circulatory system, cell–cell interactions in the immune system, differentiation and protein targeting to cellular compartments, as well as in host defence mechanisms, inflammation, and cancer. Among all the sources of lectins, plants have been most extensively studied. However, more recently fungal lectins have attracted considerable attention due to their antitumor, antiproliferative and immunomodulatory activities. Given that only 10% of mushroom species are known and have been taxonomically classified, mushrooms represent an enormous unexplored source of potentially useful and novel lectins. In this review we provide an up-to-date summary on the biochemical, molecular and structural properties of mushroom lectins, as well as their versatile applications specifically focusing on mushroom lectin bioactivity. PMID:25856678
The assessment of personality disorders: implications for cognitive and behavior therapy.
Van Velzen, C J; Emmelkamp, P M
1996-08-01
This article reviews the comorbidity of personality disorders (PDs) and Axis I disorders and discusses implications for assessment and treatment. Pros and cons of various assessment methods are discussed. The co-occurrence of PDs with Axis I disorders is considerable; roughly half of patients with anxiety disorders, depressive disorders or eating disorders received a PD diagnosis. Comorbidity models are discussed and implications for assessment and treatment are provided. Regarding the impact of PDs on cognitive-behavioral treatment outcome for Axis I disorders, conflicting results are found due to differences in assessment methods, treatment strategies, and patient samples. It is argued that additional Axis I pathology should be taken into account when studying the impact of PDs on treatment outcome for the target Axis I disorders. Finally, it is argued that the interpersonal behavior of the PD patient and the therapeutic relationship deserve more attention in the assessment and treatment of patients with PDs.
A fitting empirical potential for NiTi alloy and its application
NASA Astrophysics Data System (ADS)
Ren, Guowu; Tang, Tiegang; Sehitoglu, Huseyin
Due to its superelastic behavior, NiTi shape memory alloy receives considerable attentions over a wide range of industrial and commercial applications. Limited to its complex structural transformation and multiple variants, semiempirical potentials for performing large-scale molecular dynamics simulations to investigate the atomistic mechanical process, are very few. In this work, we construct a new interatomic potential for the NiTi alloy by fitting to experimental or ab initio data. The fitting potential correctly predicts the lattice parameter, structural stability, equation of state for cubic B2(austenite) and monoclinic B19'(martensite) phases. In particular the elastic properties(three elastic constants for B2 and thirteen ones for B19') are in satisfactory agreement with the experiments or ab initio calculations. Furthermore, we apply this potential to conduct the molecular dynamics simulations of the mechanical behavior for NiTi alloy and the results capture its reversible transformation.
Anomalous cation diffusion in salt-doped confined bilayer ice.
Qiu, Hu; Xue, Minmin; Shen, Chun; Guo, Wanlin
2018-05-17
The diffusive dynamics of aqueous electrolyte solutions in nanoconfined spaces has attracted considerable attention due to their potential applications in desalination, biosensors and supercapacitors. Here we show by molecular dynamics simulations that lithium and sodium ions diffuse at a rate at least an order of magnitude higher than that of water molecules when the ions are trapped in an ice bilayer confined between two parallel plates. This novel picture is in sharp contrast to the prevailing view that the diffusion rate of ions is comparable to or even lower than that of water in both bulk and confined solutions. The predicted high ion mobility stems from frequent lateral hopping of ions along the coordination sites inside the hydrogen-bonding network connecting the two water layers of the ice bilayer. This anomalous diffusion should provide new insights into the physics of confined aqueous electrolytes.
Purely hydrodynamic ordering of rotating disks at a finite Reynolds number.
Goto, Yusuke; Tanaka, Hajime
2015-01-28
Self-organization of moving objects in hydrodynamic environments has recently attracted considerable attention in connection to natural phenomena and living systems. However, the underlying physical mechanism is much less clear due to the intrinsically nonequilibrium nature, compared with self-organization of thermal systems. Hydrodynamic interactions are believed to play a crucial role in such phenomena. To elucidate the fundamental physical nature of many-body hydrodynamic interactions at a finite Reynolds number, here we study a system of co-rotating hard disks in a two-dimensional viscous fluid at zero temperature. Despite the absence of thermal noise, this system exhibits rich phase behaviours, including a fluid state with diffusive dynamics, a cluster state, a hexatic state, a glassy state, a plastic crystal state and phase demixing. We reveal that these behaviours are induced by the off-axis and many-body nature of nonlinear hydrodynamic interactions and the finite time required for propagating the interactions by momentum diffusion.
Anti-biofouling superhydrophobic surface fabricated by picosecond laser texturing of stainless steel
NASA Astrophysics Data System (ADS)
Sun, Ke; Yang, Huan; Xue, Wei; He, An; Zhu, Dehua; Liu, Wenwen; Adeyemi, Kenneth; Cao, Yu
2018-04-01
Anti-biofouling technology is based on specifically designed materials and coatings. This is an enduring goal in the maritime industries, such as shipping, offshore oil exploration, and aquaculture. Recently, research of the relationship between wettability and antifouling effectiveness has attracted considerable attention, due to the anti-biofouling properties of the lotus leaf and shark skin. In this study, super-hydrophobic surfaces (SHSs) with controllable periodic structures were fabricated on AISI304 stainless steel by a picosecond laser, and their anti-biofouling performance were investigated by seawater immersion for five weeks in summertime. The results showed that the specimens with SHS demonstrate significant anti-biofouling effect as compared with the bare stainless steel plate. We observed that nearly 50% decrease of the average microbe attachment area ratio (Avg. MAAR) could be obtained. The micro-groove SHS with more abundant hierarchical micro-nano structures showed better anti-biofouling performance than the micro-pit SHS.
Xu, Lin; Yang, Hai-Bo
2016-06-01
During the past few decades, the construction of various kinds of platinum-acetylide complexes has attracted considerable attention, because of their wide applications in photovoltaic cells, non-linear optics, and bio-imaging materials. Among these platinum-acetylide complexes, the linear neutral platinum-acetylide complexes, due to their attractive properties, such as well-defined linear geometry, synthetic accessibility, and intriguing photoproperties, have emerged as a rising star in this field. In this personal account, we will discuss how we entered the field of linear neutral platinum-acetylide chemistry and what we found in this field. The preparation of various types of linear neutral platinum-acetylide complexes and their applications in the areas of micro/nanostructure materials, complicated topologies, and dye-sensitized solar cells will be summarized in this account. © 2016 The Chemical Society of Japan & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Excitons in boron nitride single layer
NASA Astrophysics Data System (ADS)
Galvani, Thomas; Paleari, Fulvio; Miranda, Henrique P. C.; Molina-Sánchez, Alejandro; Wirtz, Ludger; Latil, Sylvain; Amara, Hakim; Ducastelle, François
2016-09-01
Boron nitride single layer belongs to the family of two-dimensional materials whose optical properties are currently receiving considerable attention. Strong excitonic effects have already been observed in the bulk and still stronger effects are predicted for single layers. We present here a detailed study of these properties by combining ab initio calculations and a tight-binding Wannier analysis in both real and reciprocal space. Due to the simplicity of the band structure with single valence (π ) and conduction (π*) bands the tight-binding analysis becomes quasiquantitative with only two adjustable parameters and provides tools for a detailed analysis of the exciton properties. Strong deviations from the usual hydrogenic model are evidenced. The ground-state exciton is not a genuine Frenkel exciton, but a very localized tightly bound one. The other ones are similar to those found in transition-metal dichalcogenides and, although more localized, can be described within a Wannier-Mott scheme.
Recent progress in the synthesis of metal–organic frameworks
Sun, Yujia; Zhou, Hong -Cai
2015-09-25
Metal–organic frameworks (MOFs) have attracted considerable attention for various applications due to their tunable structure, porosity and functionality. In general, MOFs have been synthesized from isolated metal ions and organic linkers under hydrothermal or solvothermal conditions via one-spot reactions. The emerging precursor approach and kinetically tuned dimensional augmentation strategy add more diversity to this field. In addition, to speed up the crystallization process and create uniform crystals with reduced size, many alternative synthesis routes have been explored. Recent advances in microwave-assisted synthesis and electrochemical synthesis are presented in this review. In recent years, post-synthetic approaches have been shown to bemore » powerful tools to synthesize MOFs with modified functionality, which cannot be attained via de novo synthesis. In this study, some current accomplishments of post-synthetic modification (PSM) based on covalent transformations and coordinative interactions as well as post-synthetic exchange (PSE) in robust MOFs are provided.« less
Borisov, Dmitry A; Vil’, Vera A; Dembitsky, Valery M
2014-01-01
Summary The present review describes the current status of synthetic five and six-membered cyclic peroxides such as 1,2-dioxolanes, 1,2,4-trioxolanes (ozonides), 1,2-dioxanes, 1,2-dioxenes, 1,2,4-trioxanes, and 1,2,4,5-tetraoxanes. The literature from 2000 onwards is surveyed to provide an update on synthesis of cyclic peroxides. The indicated period of time is, on the whole, characterized by the development of new efficient and scale-up methods for the preparation of these cyclic compounds. It was shown that cyclic peroxides remain unchanged throughout the course of a wide range of fundamental organic reactions. Due to these properties, the molecular structures can be greatly modified to give peroxide ring-retaining products. The chemistry of cyclic peroxides has attracted considerable attention, because these compounds are used in medicine for the design of antimalarial, antihelminthic, and antitumor agents. PMID:24454562
Direct observation of the M2 phase with its Mott transition in a VO2 film
NASA Astrophysics Data System (ADS)
Kim, Hoon; Slusar, Tetiana V.; Wulferding, Dirk; Yang, Ilkyu; Cho, Jin-Cheol; Lee, Minkyung; Choi, Hee Cheul; Jeong, Yoon Hee; Kim, Hyun-Tak; Kim, Jeehoon
2016-12-01
In VO2, the explicit origin of the insulator-to-metal transition is still disputable between Peierls and Mott insulators. Along with the controversy, its second monoclinic (M2) phase has received considerable attention due to the presence of electron correlation in undimerized vanadium ions. However, the origin of the M2 phase is still obscure. Here, we study a granular VO2 film using conductive atomic force microscopy and Raman scattering. Upon the structural transition from monoclinic to rutile, we observe directly an intermediate state showing the coexistence of monoclinic M1 and M2 phases. The conductivity near the grain boundary in this regime is six times larger than that of the grain core, producing a donut-like landscape. Our results reveal an intra-grain percolation process, indicating that VO2 with the M2 phase is a Mott insulator.
Tubular-Type Hydroturbine Performance for Variable Guide Vane Opening by CFD
NASA Astrophysics Data System (ADS)
Kim, Y. T.; Nam, S. H.; Cho, Y. J.; Hwang, Y. C.; Choi, Y. D.; Nam, C. D.; Lee, Y. H.
Micro hydraulic power generation which has output of less or equal to 100kW is attracting considerable attention. This is because of its small, simple, renewable, and large amount of energy resources. By using a small hydro power generator of which main concept is based on using differential water pressures in pipe lines, energy which was initially wasted by use of a reducing valve at an end of the pipeline, is collected by a turbine in the hydro power generator. A propeller shaped hydroturbine has been used in order to make use of this renewable pressure energy. In this study, in order to acquire basic design data of tubular type hydroturbine, output power, head, and efficiency characteristics due to the guide vane opening angle are examined in detail. Moreover, influences of pressure, tangential and axial velocity distributions on turbine performance are investigated by using a commercial CFD code.
Dynamics in hybrid complex systems of switches and oscillators
NASA Astrophysics Data System (ADS)
Taylor, Dane; Fertig, Elana J.; Restrepo, Juan G.
2013-09-01
While considerable progress has been made in the analysis of large systems containing a single type of coupled dynamical component (e.g., coupled oscillators or coupled switches), systems containing diverse components (e.g., both oscillators and switches) have received much less attention. We analyze large, hybrid systems of interconnected Kuramoto oscillators and Hopfield switches with positive feedback. In this system, oscillator synchronization promotes switches to turn on. In turn, when switches turn on, they enhance the synchrony of the oscillators to which they are coupled. Depending on the choice of parameters, we find theoretically coexisting stable solutions with either (i) incoherent oscillators and all switches permanently off, (ii) synchronized oscillators and all switches permanently on, or (iii) synchronized oscillators and switches that periodically alternate between the on and off states. Numerical experiments confirm these predictions. We discuss how transitions between these steady state solutions can be onset deterministically through dynamic bifurcations or spontaneously due to finite-size fluctuations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shamir, M. F., E-mail: farasat.shamir@nu.edu.pk
Modified theories of gravity have attracted much attention of the researchers in the recent years. In particular, the f(R) theory has been investigated extensively due to important f(R) gravity models in cosmological contexts. This paper is devoted to exploring an anisotropic universe in metric f(R) gravity. A locally rotationally symmetric Bianchi type I cosmological model is considered for this purpose. Exact solutions of modified field equations are obtained for a well-known f(R) gravity model. The energy conditions are also discussed for the model under consideration. The viability of the model is investigated via graphical analysis using the present-day values ofmore » cosmological parameters. The model satisfies null energy, weak energy, and dominant energy conditions for a particular range of the anisotropy parameter while the strong energy condition is violated, which shows that the anisotropic universe in f(R) gravity supports the crucial issue of accelerated expansion of the universe.« less
Magnetodielectric effect in (1 - x)(Ba0.88Ca0.12)(Ti0.88Zr0.12)O3 - xCoFe2O4
NASA Astrophysics Data System (ADS)
Pan, Pengfei; Tao, Jin; Ma, Fusheng; Zhang, Ning
2018-05-01
Magnetodielectric (MD) materials have attracted considerable attention due to their intriguing physics and potential future applications. In this work, polycrystalline (1 - x)(Ba0.88Ca0.12)(Ti0.88Zr0.12)O3 - xCoFe2O4 (x = 0.10, 0.20, 0.30, 0.40) ceramic have been prepared via sol-gel method. The room temperature magnetic and ferroelectric behaviors of the synthesized composites were investigated. For the composite with x = 0.40, a MD ratio of 5.37% was achieved under a magnetic field of 1.5 T at f = 1 kHz. The measured "butterfly hysteresis" MD curves exhibit an obvious dielectric anomaly. Theoretical analysis suggests that the observed magnetodielectric effect is attributed to the magnetoresistance effect and magnetoelectric coupling.
Prediction of protein post-translational modifications: main trends and methods
NASA Astrophysics Data System (ADS)
Sobolev, B. N.; Veselovsky, A. V.; Poroikov, V. V.
2014-02-01
The review summarizes main trends in the development of methods for the prediction of protein post-translational modifications (PTMs) by considering the three most common types of PTMs — phosphorylation, acetylation and glycosylation. Considerable attention is given to general characteristics of regulatory interactions associated with PTMs. Different approaches to the prediction of PTMs are analyzed. Most of the methods are based only on the analysis of the neighbouring environment of modification sites. The related software is characterized by relatively low accuracy of PTM predictions, which may be due both to the incompleteness of training data and the features of PTM regulation. Advantages and limitations of the phylogenetic approach are considered. The prediction of PTMs using data on regulatory interactions, including the modular organization of interacting proteins, is a promising field, provided that a more carefully selected training data will be used. The bibliography includes 145 references.
NASA Astrophysics Data System (ADS)
Lee, Young Tack; Hwang, Do Kyung; Choi, Won Kook
2016-10-01
Two-dimensional (2D) van der Waals (vdW) atomic crystals have been extensively studied and significant progress has been made. The newest 2D vdW material, called black phosphorus (BP), has attracted considerable attention due to its unique physical properties, such as its being a singlecomponent material like graphene, and its having a high mobility and direct band gap. Here, we report on a high-performance BP nanosheet based ferroelectric field effect transistor (FeFET) with a poly(vinylidenefluoride-trifluoroethylene) top-gate insulator for a nonvolatile memory application. The BP FeFETs show the highest linear hole mobility of 563 cm2/Vs and a clear memory window of more than 15 V. For more advanced nonvolatile memory circuit applications, two different types of resistive-load and complementary ferroelectric memory inverters were implemented, which showed distinct memory on/off switching characteristics.
Mehdizadeh, Tooraj; Tajik, Hossein; Razavi Rohani, Seyed Mehdi; Oromiehie, Abdol Rassol
2012-01-01
Thyme Essential oils (EO) with antimicrobial and antioxidant properties are widely used in pharmaceutical, cosmetic, and perfume industry. It is also used for flavoring and preservation of several foods. Nowadays, packaging research is receiving a considerable attention due to the development of eco-friendly materials made from natural polymers such as starch and chitosan. In this study Thymus kotschyanus EO concentrations ranging from 0 to 2.0%, incorporated in starch-chitosan composite (S-CH) film were used. Antimicrobial and antioxidant properties significantly increased with the incorporation of EO (p < 0.05). Incorporating EO, increased total color differences (DE), yellowness index (YI) and whiteness index (WI) which were significantly higher than control and its transparency was reduced. Our results pointed out that the incorporation of Thymus kotschyanus EO as a natural antibacterial agent has potential for using the developed film as an active packaging. PMID:25610564
Nanodiamonds carrying silicon-vacancy quantum emitters with almost lifetime-limited linewidths
NASA Astrophysics Data System (ADS)
Jantzen, Uwe; Kurz, Andrea B.; Rudnicki, Daniel S.; Schäfermeier, Clemens; Jahnke, Kay D.; Andersen, Ulrik L.; Davydov, Valery A.; Agafonov, Viatcheslav N.; Kubanek, Alexander; Rogers, Lachlan J.; Jelezko, Fedor
2016-07-01
Colour centres in nanodiamonds are an important resource for applications in quantum sensing, biological imaging, and quantum optics. Here we report unprecedented narrow optical transitions for individual colour centres in nanodiamonds smaller than 200 nm. This demonstration has been achieved using the negatively charged silicon vacancy centre, which has recently received considerable attention due to its superb optical properties in bulk diamond. We have measured an ensemble of silicon-vacancy centres across numerous nanodiamonds to have an inhomogeneous distribution of 1.05 nm at 5 K. Individual spectral lines as narrower than 360 MHz were measured in photoluminescence excitation, and correcting for apparent spectral diffusion yielded an homogeneous linewidth of about 200 MHz which is close to the lifetime limit. These results indicate the high crystalline quality achieved in these nanodiamond samples, and advance the applicability of nanodiamond-hosted colour centres for quantum optics applications.
Sentiment analysis using common-sense and context information.
Agarwal, Basant; Mittal, Namita; Bansal, Pooja; Garg, Sonal
2015-01-01
Sentiment analysis research has been increasing tremendously in recent times due to the wide range of business and social applications. Sentiment analysis from unstructured natural language text has recently received considerable attention from the research community. In this paper, we propose a novel sentiment analysis model based on common-sense knowledge extracted from ConceptNet based ontology and context information. ConceptNet based ontology is used to determine the domain specific concepts which in turn produced the domain specific important features. Further, the polarities of the extracted concepts are determined using the contextual polarity lexicon which we developed by considering the context information of a word. Finally, semantic orientations of domain specific features of the review document are aggregated based on the importance of a feature with respect to the domain. The importance of the feature is determined by the depth of the feature in the ontology. Experimental results show the effectiveness of the proposed methods.
Superconductivity in multiple phases of compressed GeS b2T e4
NASA Astrophysics Data System (ADS)
Greenberg, E.; Hen, B.; Layek, Samar; Pozin, I.; Friedman, R.; Shelukhin, V.; Rosenberg, Y.; Karpovski, M.; Pasternak, M. P.; Sterer, E.; Dagan, Y.; Rozenberg, G. Kh.; Palevski, A.
2017-02-01
Here we report the discovery of superconductivity in multiple phases of the compressed GeS b2T e4 (GST) phase change memory alloy, which has attracted considerable attention for the last decade due to its unusual physical properties with many potential applications. Superconductivity is observed through electrical transport measurements, both for the amorphous (a -GST) and for the crystalline (c -GST) phases. The superconducting critical temperature Tc continuously increases with applied pressure, reaching a maximum Tc=6 K at P =20 GPa for a -GST, whereas the critical temperature of the cubic phase reaches a maximum Tc=8 K at 30 GPa. This material system, exhibiting a superconductor-insulator quantum phase transition, has an advantage over disordered metals since it has a continuous control of the crystal structure and the electronic properties using pressure as an external stimulus.
Road safety in the Eastern Mediterranean Region--findings from the Global Road Safety Status Report.
Soori, H; Hussain, S J; Razzak, J A
2011-10-01
A secondary data analysis using the Global Status Report on Road Safety (GSRRS) was carried out to assess the epidemiology of road traffic injuries (RTIs) and preventive strategies in the Eastern Mediterranean egion (EMR). EMR countries ranked equal first in the world for the highest number of fatalities due to RTIs (32.2 per 100 000 population). The region had about 4% of the world's vehicles with 0.097 registered vehicles per person. The number of injured cases in EMR was 210.1 per 100 000 population. Only 15% of EMR countries had a funded, independent, multisectoral body for road safety. Only 25% had mandatory seat-belt laws for both front-seat and rear-seat passengers, 60% had mandatory helmet laws for both drivers and passengers of motorized two-wheelers and 10% had child restraint laws. Road safety in EMR countries needs more attention and consideration.
Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications
Nabavi, Seyed Fazel; Habtemariam, Solomon; Ahmed, Touqeer; Sureda, Antoni; Daglia, Maria; Sobarzo-Sánchez, Eduardo; Nabavi, Seyed Mohammad
2015-01-01
The abundance of scientific evidence has shown that many synthetic drugs can cause serious adverse effects in patients. Recently, the search of natural therapeutic agents with low adverse effects has attracted much attention. In particular, considerable interest has focused on edible and medicinal plants, which play an important role in human diet, and have been used for disease treatment since ancient times. Crataegus monogyna Jacq. (hawthorn) is one of the most important edible plants of the Rosaceae family and is also used in traditional medicine. Growing evidence has shown that this plant has various interesting physiological and pharmacological activities due to the presence of different bioactive natural compounds. In addition, scientific evidence suggests that the toxicity of hawthorn is negligible. Therefore, the aim of this paper is to provide a critical review of the available scientific literature about pharmacological activities as well as botanical aspects, phytochemistry and clinical impacts of C. monogyna. PMID:26378574
Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications.
Nabavi, Seyed Fazel; Habtemariam, Solomon; Ahmed, Touqeer; Sureda, Antoni; Daglia, Maria; Sobarzo-Sánchez, Eduardo; Nabavi, Seyed Mohammad
2015-09-11
The abundance of scientific evidence has shown that many synthetic drugs can cause serious adverse effects in patients. Recently, the search of natural therapeutic agents with low adverse effects has attracted much attention. In particular, considerable interest has focused on edible and medicinal plants, which play an important role in human diet, and have been used for disease treatment since ancient times. Crataegus monogyna Jacq. (hawthorn) is one of the most important edible plants of the Rosaceae family and is also used in traditional medicine. Growing evidence has shown that this plant has various interesting physiological and pharmacological activities due to the presence of different bioactive natural compounds. In addition, scientific evidence suggests that the toxicity of hawthorn is negligible. Therefore, the aim of this paper is to provide a critical review of the available scientific literature about pharmacological activities as well as botanical aspects, phytochemistry and clinical impacts of C. monogyna.
Synthesis of nanosize MCM-41 loaded with TiO 2 and study of its photocatalytic activity
NASA Astrophysics Data System (ADS)
Sadjadi, M. S.; Farhadyar, N.; Zare, K.
2009-07-01
In recent years, nanosized mesoporous materials have received significant attention due to their impact in different processes. Several diverse applications of these materials, e.g. high density magnetic recording, magnetic fluids, magnetic refrigeration as well as in photocatalysis, solar cells, photosensors, have triggered considerable research activities in the area of nanotechnology. In this work, nanosize MCM-41 was synthesized and loaded then with TiO 2 using tetra butoxy titanium (TBT). As prepared TiO 2 loaded materials was investigated by using X-ray diffraction (XRD), Transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR). The photocatalytic activity of the prepared TiO 2 loaded MCM-41 was finally evaluated by the degradation of methyl orange under irradiation of UV light. The result showed that TiO 2 loaded on nanosize MCM-41 has higher photocatalytic activity than that of TiO 2.
Optical arc sensor using energy harvesting power source
DOE Office of Scientific and Technical Information (OSTI.GOV)
Choi, Kyoo Nam, E-mail: knchoi@inu.ac.kr; Rho, Hee Hyuk, E-mail: rdoubleh0902@inu.ac.kr
Wireless sensors without external power supply gained considerable attention due to convenience both in installation and operation. Optical arc detecting sensor equipping with self sustaining power supply using energy harvesting method was investigated. Continuous energy harvesting method was attempted using thermoelectric generator to supply standby power in micro ampere scale and operating power in mA scale. Peltier module with heat-sink was used for high efficiency electricity generator. Optical arc detecting sensor with hybrid filter showed insensitivity to fluorescent and incandescent lamps under simulated distribution panel condition. Signal processing using integrating function showed selective arc discharge detection capability to different arcmore » energy levels, with a resolution below 17 J energy difference, unaffected by bursting arc waveform. The sensor showed possibility for application to arc discharge detecting sensor in power distribution panel. Also experiment with proposed continuous energy harvesting method using thermoelectric power showed possibility as a self sustainable power source of remote sensor.« less
Martorell, A; García-Martínez, F J; Jiménez-Gallo, D; Pascual, J C; Pereyra-Rodriguez, J; Salgado, L; Vilarrasa, E
2015-11-01
Hidradenitis suppurativa is a chronic inflammatory disorder that has attracted increasing attention in recent years due to underestimations of prevalence and the considerable impact of the condition on interpersonal relationships, physical appearance, self-esteem, and body image. Although hidradenitis suppurative has a significant psychological impact on patients and can even cause physical limitations when thick scarring results in limb mobility limitation, until very recently little evidence was available relating to its epidemiology, etiology, or pathogenesis. In this review, we highlight the latest advances in our understanding of the epidemiological and clinical aspects of hidradenitis suppurativa. We will also look at the different classification systems for hidradenitis suppurativa and discuss the emergence of skin ultrasound as a promising technique for monitoring the course of this chronic inflammatory disease. Copyright © 2015 Elsevier España, S.L.U. and AEDV. All rights reserved.
Issues deserve attention in encapsulating probiotics: Critical review of existing literature.
Chen, Jun; Wang, Qi; Liu, Cheng-Mei; Gong, Joshua
2017-04-13
Probiotic bacteria are being increasingly added to food for developing products with health-promoting properties. However, the efficacy of probiotics in commercial products is often questioned due to the loss of their viability during shelf storage and in human gastrointestinal tracts. Encapsulation of probiotics has been expected to provide protection to probiotics, but not many commercial products contain encapsulated and viable probiotic cells owing to various reasons. To promote the development and application of encapsulation technologies, this paper has critically reviewed previous publications with a focus on the areas where studies have fallen short, including insufficient consideration of structural effects of encapsulating material, general defects in encapsulating methods and issues in evaluation methodologies and risk assessments for application. Corresponding key issues that require further studies are highlighted. Some emerging trends in the field, such as current treads in encapsulating material and recently advanced encapsulation techniques, have also been discussed.
Deep Brain Stimulation for Dystonia: A Novel Perspective on the Value of Genetic Testing
Jinnah, H. A.; Alterman, Ron; Klein, Christine; Krauss, Joachim K.; Moro, Elena; Vidailhet, Marie; Raike, Robert
2017-01-01
The dystonias are a group of disorders characterized by excessive muscle contractions leading to abnormal movements and postures. There are many different clinical manifestations and underlying causes. Deep brain stimulation (DBS) provides an effect treatment, but outcomes can vary considerably among the different subtypes of dystonia. Several variables are thought to contribute to this variation including age of onset and duration of dystonia, specific characteristics of the dystonic movements, location of stimulation and stimulator settings, and others. The potential contributions of genetic factors have received little attention. In this review, we summarize evidence that some of the variation in DBS outcomes for dystonia is due to genetic factors. The evidence suggests that more methodical genetic testing may provide useful information in the assessment of potential surgical candidates, and in advancing our understanding of the biological mechanisms that influence DBS outcomes. PMID:28160152
Iyer, Swami; Reyes, Joshua; Killingback, Timothy
2014-01-01
The Traveler's Dilemma game and the Minimum Effort Coordination game are two social dilemmas that have attracted considerable attention due to the fact that the predictions of classical game theory are at odds with the results found when the games are studied experimentally. Moreover, a direct application of deterministic evolutionary game theory, as embodied in the replicator dynamics, to these games does not explain the observed behavior. In this work, we formulate natural variants of these two games as smoothed continuous-strategy games. We study the evolutionary dynamics of these continuous-strategy games, both analytically and through agent-based simulations, and show that the behavior predicted theoretically is in accord with that observed experimentally. Thus, these variants of the Traveler's Dilemma and the Minimum Effort Coordination games provide a simple resolution of the paradoxical behavior associated with the original games. PMID:24709851
Iyer, Swami; Reyes, Joshua; Killingback, Timothy
2014-01-01
The Traveler's Dilemma game and the Minimum Effort Coordination game are two social dilemmas that have attracted considerable attention due to the fact that the predictions of classical game theory are at odds with the results found when the games are studied experimentally. Moreover, a direct application of deterministic evolutionary game theory, as embodied in the replicator dynamics, to these games does not explain the observed behavior. In this work, we formulate natural variants of these two games as smoothed continuous-strategy games. We study the evolutionary dynamics of these continuous-strategy games, both analytically and through agent-based simulations, and show that the behavior predicted theoretically is in accord with that observed experimentally. Thus, these variants of the Traveler's Dilemma and the Minimum Effort Coordination games provide a simple resolution of the paradoxical behavior associated with the original games.
Unconscious emotion: A cognitive neuroscientific perspective.
Smith, Ryan; Lane, Richard D
2016-10-01
While psychiatry and clinical psychology have long discussed the topic of unconscious emotion, and its potentially explanatory role in psychopathology, this topic has only recently begun to receive attention within cognitive neuroscience. In contrast, neuroscientific research on conscious vs. unconscious processes within perception, memory, decision-making, and cognitive control has seen considerable advances in the last two decades. In this article, we extrapolate from this work, as well as from recent neural models of emotion processing, to outline multiple plausible neuro-cognitive mechanisms that may be able to explain why various aspects of one's own emotional reactions can remain unconscious in specific circumstances. While some of these mechanisms involve top-down or motivated factors, others instead arise due to bottom-up processing deficits. Finally, we discuss potential implications that these different mechanisms may have for therapeutic intervention, as well as how they might be tested in future research. Copyright © 2016 Elsevier Ltd. All rights reserved.
Chen, Hong; Lin, Hua; Liu, Yi; Wu, Xin-Tao; Wu, Li-Ming
2017-11-07
The chemistry of copper-based chalcogenides has received considerable attention due to their diverse structures and potential applications in the area of thermoelectric (TE) materials. In this communication, a series of spinel-type Cu 4 Mn 2 Te 4 -based samples have been successfully prepared and their high TE performances are attributed to the enhanced power factor and low thermal conductivity via the synergistic effect of Te deficiency and Cl doping. Consequently, a maximum TE figure of merit (ZT) of ∼0.4 was achieved for the Cu 4 Mn 2 Te 3.93 Cl 0.03 sample at 700 K, which was about 100% enhanced in comparison with the undoped Cu 4 Mn 2 Te 4 sample and one of the highest ZT values reported for p-type spinel tellurides.
Remote Respiration Monitoring Using Ultra-wideband Microwave Sensor
NASA Astrophysics Data System (ADS)
Higashikatsuragi, Kenji; Nakahata, Youichiro; Matsunami, Isamu; Kajiwara, Akihiro
Impulse based ultra-wideband radio has lately attracted considerable attention as medical monitoring sensor since it is expected to measure bio-signals of a patient on a bed such as respiration rate and heartbeat with a remote non-contact approach. It is also friendly to the environment including the human body due to the very low electromagnetic energy emission. Using conventional ranging scheme, however, high speed A/D device should be required in order to detect the small respiratory displacement. This paper suggests a respiratory monitoring scheme where the respiration rate is measured by observing the variation of the path strength from the patient. Therefore, it does not require high speed A/D. It also makes possible to design the simultaneous monitoring of multiple patients in hospital beds, for example. In this paper the measurements were conducted for various scenarios and the feasibility is discussed.
Optical arc sensor using energy harvesting power source
NASA Astrophysics Data System (ADS)
Choi, Kyoo Nam; Rho, Hee Hyuk
2016-06-01
Wireless sensors without external power supply gained considerable attention due to convenience both in installation and operation. Optical arc detecting sensor equipping with self sustaining power supply using energy harvesting method was investigated. Continuous energy harvesting method was attempted using thermoelectric generator to supply standby power in micro ampere scale and operating power in mA scale. Peltier module with heat-sink was used for high efficiency electricity generator. Optical arc detecting sensor with hybrid filter showed insensitivity to fluorescent and incandescent lamps under simulated distribution panel condition. Signal processing using integrating function showed selective arc discharge detection capability to different arc energy levels, with a resolution below 17J energy difference, unaffected by bursting arc waveform. The sensor showed possibility for application to arc discharge detecting sensor in power distribution panel. Also experiment with proposed continuous energy harvesting method using thermoelectric power showed possibility as a self sustainable power source of remote sensor.
Design of a fault-tolerant reversible control unit in molecular quantum-dot cellular automata
NASA Astrophysics Data System (ADS)
Bahadori, Golnaz; Houshmand, Monireh; Zomorodi-Moghadam, Mariam
Quantum-dot cellular automata (QCA) is a promising emerging nanotechnology that has been attracting considerable attention due to its small feature size, ultra-low power consuming, and high clock frequency. Therefore, there have been many efforts to design computational units based on this technology. Despite these advantages of the QCA-based nanotechnologies, their implementation is susceptible to a high error rate. On the other hand, using the reversible computing leads to zero bit erasures and no energy dissipation. As the reversible computation does not lose information, the fault detection happens with a high probability. In this paper, first we propose a fault-tolerant control unit using reversible gates which improves on the previous design. The proposed design is then synthesized to the QCA technology and is simulated by the QCADesigner tool. Evaluation results indicate the performance of the proposed approach.
Synthesis of V2O5 microspheres by spray pyrolysis as cathode material for supercapacitors
NASA Astrophysics Data System (ADS)
Yin, Zhendong; Xu, Jie; Ge, Yali; Jiang, Qiaoya; Zhang, Yaling; Yang, Yawei; Sun, Yuping; Hou, Siyu; Shang, Yuanyuan; Zhang, Yingjiu
2018-03-01
Vanadium oxide (V2O5) microspheres have attracted considerable attention in the energy field due to their unique properties such as high stability and electrochemical activity. Here, massive V2O5 microspheres with smooth surface, hollow cavity and uniform particle sizes (0.4–1.5 μm), were synthesized by a facile spray pyrolysis process. Post-treatment at predefined temperatures effectively turned the microsphere shell into stacked nanorods with widths of 100 nm and lengths of 500 nm when processed at 500 °C for 3 h under nitrogen atmosphere, with enhanced crystallinity. When applied as cathode materials for supercapacitors, the post-treated V2O5 microspheres at 500 °C exhibited improved specific capacitance and longer discharge time. This is an effective method to manufacture massive V2O5 microspheres with tailored structure and potential applications in high-performance energy storage materials.
Gradual cut detection using low-level vision for digital video
NASA Astrophysics Data System (ADS)
Lee, Jae-Hyun; Choi, Yeun-Sung; Jang, Ok-bae
1996-09-01
Digital video computing and organization is one of the important issues in multimedia system, signal compression, or database. Video should be segmented into shots to be used for identification and indexing. This approach requires a suitable method to automatically locate cut points in order to separate shot in a video. Automatic cut detection to isolate shots in a video has received considerable attention due to many practical applications; our video database, browsing, authoring system, retrieval and movie. Previous studies are based on a set of difference mechanisms and they measured the content changes between video frames. But they could not detect more special effects which include dissolve, wipe, fade-in, fade-out, and structured flashing. In this paper, a new cut detection method for gradual transition based on computer vision techniques is proposed. And then, experimental results applied to commercial video are presented and evaluated.
Surface Modification of Cu(In,Ga)Se2 Grains
NASA Astrophysics Data System (ADS)
Alruqobah, Essam H.
Nearly all of the world’s energy demand today is being met by the use of non-renewable energy sources. With the worldwide energy demand projected to increase in the coming years, it is vital to find alternative and renewable energy sources. Among the available renewable energy sources, solar energy is the most promising in meeting the worldwide energy demand. Recently, thin film solar cells have garnered attention due to their thinner architecture and relatively high optical absorption coefficients, as opposed to the conventional crytslline silicon solar cells. One of the most promising thin-film solar cell absorber materials is Cu(In,Ga)Se2 (CIGSe), achieving power conversion efficiencies approaching those of crystalline Si. The highest efficiency CIGSe devices were made via costly vacuum-based co-evaporation process. CIGSe devices made from solution-processed methods have also garnered attention due to their lower costs, and their efficiencies have increased considerably in recent years. In this thesis, CIGSe absorber layers are fabricated via the solution-processed from nanoparticle-based sulfide CIGS. The most important step in fabrication of a CIGSe solar cell absorber layer is the selenization step, which is the thermal sintering of a CIGSe precursor layer in the presence of selenium vapor to achieve large, dense selenide grains that are required for adequate PV performance. It is determined that maintaining adequate selenium vapor pressure on the substrate during the selenization and subsequent cooldown is crucial in producing high efficiency solar cell devices. Furthermore, exposing the CIGSe grains to a Se-deficient atmosphere causes Se to evaporate from the grains, and subsequently modifying the CIGSe grain surface. The modified grain surface adversely impacts the PV performance of the final solar cell device by forming defects due to the decrease in selenium concentration. These defects are manifested in increased current shunting, and decrease the overall efficiency of the device.
Attention networks in adolescent anorexia nervosa.
Weinbach, Noam; Sher, Helene; Lock, James D; Henik, Avishai
2018-03-01
Anorexia nervosa (AN) usually develops during adolescence when considerable structural and functional brain changes are taking place. Neurocognitive inefficiencies have been consistently found in adults with enduring AN and were suggested to play a role in maintaining the disorder. However, such findings are inconsistent in children and adolescents with AN. The current study conducted a comprehensive assessment of attention networks in adolescents with AN who were not severely underweight during the study using an approach that permits disentangling independent components of attention. Twenty partially weight-restored adolescents with AN (AN-WR) and 24 healthy adolescents performed the Attention Network Test which assesses the efficiency of three main attention networks-executive control, orienting, and alerting. The results revealed abnormal function in the executive control network among adolescents with AN-WR. Specifically, adolescents with AN-WR demonstrated superior ability to suppress attention to task-irrelevant information while focusing on a central task. Moreover, the alerting network modulated this ability. No difference was found between the groups in the speed of orienting attention, but reorienting attention to a target resulted in higher error rates in the AN-WR group. The findings suggest that adolescents with AN have attentional abnormalities that cannot be explained by a state of starvation. These attentional dysregulations may underlie clinical phenotypes of the disorder such as increased attention of details.
Pitzianti, Mariabernarda; D'Agati, Elisa; Casarelli, Livia; Pontis, Marco; Kaunzinger, Ivo; Lange, Klaus W; Tucha, Oliver; Curatolo, Paolo; Pasini, Augusto
2016-11-01
Inattention is one of the core symptoms of Attention Deficit Hyperactivity Disorder (ADHD). Most of patients with ADHD show motor impairment, consisting in the persistence of neurological soft signs (NSS). Our aim was to evaluate attentional and motor functioning in an ADHD sample and healthy children (HC) and possible link between attentional dysfunction and motor impairment in ADHD. Twenty-seven drug-naive patients with ADHD and 23 HC were tested with a test battery, measuring different aspects of attention. Motor evaluation has provided three primary variables: overflow movements (OM), dysrhythmia and total speed of timed activities. Compared to HC, patients were impaired in a considerable number of attentional processes and showed a greater number of NSS. Significant correlations between disturbances of attention and motor abnormalities were observed in ADHD group. Our findings suggest that attentional processes could be involved in the pathophysiology of the NSS and add scientific evidence to the predictive value of NSS as indicators of the severity of functional impairment in ADHD. Given the marked improvement or complete resolution of NSS following treatment with methylphenidate, we suggest that evaluation of NSS is useful to monitor the effectiveness of pharmacological treatment with MPH in ADHD.
Attention deficit hyperactivity disorder--a review.
Williams, C; Wright, B; Partridge, I
1999-01-01
The topic of attention deficit hyperactivity disorder (ADHD) is fascinating and controversial. A variety of stances have been taken by different clinicians, support groups, and the media. A nature/nurture argument has developed that may have a tendency to polarize views. This review aims to present research findings that inform the debate. It deals with symptomatology, aetiology, and prevalence, with assessment for diagnosis, management, and outcome. The importance of comprehensive management taking into consideration not just attention abilities but a range of other factors that have an impact upon them is stressed. Management should be pragmatic, multifaceted, and based around the establishment of good working relationships with family and school. PMID:10621994
Individual differences in selective attention predict speech identification at a cocktail party.
Oberfeld, Daniel; Klöckner-Nowotny, Felicitas
2016-08-31
Listeners with normal hearing show considerable individual differences in speech understanding when competing speakers are present, as in a crowded restaurant. Here, we show that one source of this variance are individual differences in the ability to focus selective attention on a target stimulus in the presence of distractors. In 50 young normal-hearing listeners, the performance in tasks measuring auditory and visual selective attention was associated with sentence identification in the presence of spatially separated competing speakers. Together, the measures of selective attention explained a similar proportion of variance as the binaural sensitivity for the acoustic temporal fine structure. Working memory span, age, and audiometric thresholds showed no significant association with speech understanding. These results suggest that a reduced ability to focus attention on a target is one reason why some listeners with normal hearing sensitivity have difficulty communicating in situations with background noise.
Towards the quantitative evaluation of visual attention models.
Bylinskii, Z; DeGennaro, E M; Rajalingham, R; Ruda, H; Zhang, J; Tsotsos, J K
2015-11-01
Scores of visual attention models have been developed over the past several decades of research. Differences in implementation, assumptions, and evaluations have made comparison of these models very difficult. Taxonomies have been constructed in an attempt at the organization and classification of models, but are not sufficient at quantifying which classes of models are most capable of explaining available data. At the same time, a multitude of physiological and behavioral findings have been published, measuring various aspects of human and non-human primate visual attention. All of these elements highlight the need to integrate the computational models with the data by (1) operationalizing the definitions of visual attention tasks and (2) designing benchmark datasets to measure success on specific tasks, under these definitions. In this paper, we provide some examples of operationalizing and benchmarking different visual attention tasks, along with the relevant design considerations. Copyright © 2015 Elsevier Ltd. All rights reserved.
Relations between the Test of Variables of Attention (TOVA) and the Children's Memory Scale (CMS).
Riccio, Cynthia A; Garland, Beth H; Cohen, Morris J
2007-09-01
There is considerable overlap in the constructs of attention and memory. The objective of this study was to examine the relationship between the Test of Variables of Attention (TOVA), a measure of attention, to components of memory and learning as measured by the Children's Memory Scale (CMS). Participants (N = 105) were consecutive referrals to an out-patient facility, generally for learning or behavior problems, who were administered both the TOVA and the CMS. Significant correlations were found between the omissions score on the TOVA and subscales of the CMS. TOVA variability and TOVA reaction time correlated significantly with subscales of the CMS as well. TOVA commission errors did not correlate significantly with any CMS Index. Although significant, the correlation coefficients indicate that the CMS and TOVA are measuring either different constructs or similar constructs but in different ways. As such, both measures may be useful in distinguishing memory from attention problems.
A Review of Methods in the Study of Attention in Autism
ERIC Educational Resources Information Center
Ames, Catherine; Fletcher-Watson, Sue
2010-01-01
Atypical attention, while not a diagnostic feature, is common in individuals with autism spectrum disorders (ASD). The study of these atypicalities has recently gained in both quantity and quality, due in part to an increased focus on attentional atypicalities as one of the earliest signs of ASD in infancy. A range of attentional processes and…
Behavioral and neural stability of attention bias to threat in healthy adolescents
Britton, Jennifer C.; Sequeira, Stefanie; Ronkin, Emily G.; Chen, Gang; Bar-Haim, Yair; Shechner, Tomer; Ernst, Monique; Fox, Nathan A.; Leibenluft, Ellen; Pine, Daniel S.
2016-01-01
Considerable translational research on anxiety examines attention bias to threat and the efficacy of attention training in reducing symptoms. Imaging research on the stability of brain functions engaged by attention bias tasks could inform such research. Perturbed fronto-amygdala function consistently arises in attention bias research on adolescent anxiety. The current report examines the stability of the activation and functional connectivity of these regions on the dot-probe task. Functional magnetic resonance imaging (fMRI) activation and connectivity data were acquired with the dot-probe task in 39 healthy youth (f =18, Mean Age = 13.71 years, SD = 2.31) at two time points, separated by approximately nine weeks. Intraclass-correlations demonstrate good reliability in both neural activation for the ventrolateral PFC and task-specific connectivity for fronto-amygdala circuitry. Behavioral measures showed generally poor test-retest reliability. These findings suggest potential avenues for future brain imaging work by highlighting brain circuitry manifesting stable functioning on the dot-probe attention bias task. PMID:27129757
Sawaki, Risa; Luck, Steven J
2010-08-01
There is considerable controversy about whether salient singletons capture attention in a bottom-up fashion, irrespective of top-down control settings. One possibility is that salient singletons always generate an attention capture signal, but this signal can be actively suppressed to avoid capture. In the present study, we investigated this issue by using event-related potential recordings, focusing on N2pc (N2-posterior-contralateral; a measure of attentional deployment) and Pd (distractor positivity; a measure of attentional suppression). Participants searched for a specific letter within one of two regions, and irrelevant color singletons were sometimes present. We found that the irrelevant singletons did not elicit N2pc but instead elicited Pd; this occurred equally within the attended and unattended regions. These findings suggest that salient singletons may automatically produce an attend-to-me signal, irrespective of top-down control settings, but this signal can be overridden by an active suppression process to prevent the actual capture of attention.
Leech, Robert; Aydelott, Jennifer; Symons, Germaine; Carnevale, Julia; Dick, Frederic
2007-11-01
How does the development and consolidation of perceptual, attentional, and higher cognitive abilities interact with language acquisition and processing? We explored children's (ages 5-17) and adults' (ages 18-51) comprehension of morphosyntactically varied sentences under several competing speech conditions that varied in the degree of attentional demands, auditory masking, and semantic interference. We also evaluated the relationship between subjects' syntactic comprehension and their word reading efficiency and general 'speed of processing'. We found that the interactions between perceptual and attentional processes and complex sentence interpretation changed considerably over the course of development. Perceptual masking of the speech signal had an early and lasting impact on comprehension, particularly for more complex sentence structures. In contrast, increased attentional demand in the absence of energetic auditory masking primarily affected younger children's comprehension of difficult sentence types. Finally, the predictability of syntactic comprehension abilities by external measures of development and expertise is contingent upon the perceptual, attentional, and semantic milieu in which language processing takes place.
Safety Guidelines for Field Data Collection
DOT National Transportation Integrated Search
2010-02-01
Safety concerns are always present when personnel are working near or adjacent to a highway. Safety considerations must include the workers as well as the motoring public. Construction safety has received extensive attention, but this research focuse...
Research from Afar: Considerations for Conducting an Off-Site Research Project.
ERIC Educational Resources Information Center
Williams, Reg Arthur; Hagerty, Bonnie M.; Hoyle, Kenneth; Yousha, Steven M.; Abdoo, Yvonne; Andersen, Curt; Engler, Dorothy
1999-01-01
Critical elements in the success of off-site research projects include the following: negotiation, attention to personnel issues, communication, participation of research subjects, data management, and concern for privacy issues. (SK)
Poisoning of bubble propelled catalytic micromotors: the chemical environment matters
Zhao, Guanjia; Sanchez, Samuel; Schmidt, Oliver G.
2013-01-01
Self-propelled catalytic microjets have attracted considerable attention in recent years and these devices have exhibited the ability to move in complex media. The mechanism of propulsion is via the Pt catalysed decomposition of H2O2 and it is understood that the Pt surface is highly susceptible to poisoning by sulphur-containing molecules. Here, we show that important extracellular thiols as well as basic organic molecules can significantly hamper the motion of catalytic microjet engines. This is due to two different mechanisms: (i) molecules such as dimethyl sulfoxide can quench the hydroxyl radicals produced at Pt surfaces and reduce the amount of oxygen gas generated and (ii) molecules containing –SH, –SSR, and –SCH3 moieties can poison the catalytically active platinum surface, inhibiting the motion of the jet engines. It is essential that the presence of such molecules in the environment be taken into consideration for future design and operation of catalytic microjet engines. We show this effect on catalytic micromotors prepared by both rolled-up and electrodeposition approaches, demonstrating that such poisoning is universal for Pt catalyzed micromotors. We believe that our findings will contribute significantly to this field to develop alternative systems or catalysts for self-propulsion when practical applications in the real environment are considered. PMID:23450281
Schulze, H Georg; Turner, Robin F B
2015-06-01
High-throughput information extraction from large numbers of Raman spectra is becoming an increasingly taxing problem due to the proliferation of new applications enabled using advances in instrumentation. Fortunately, in many of these applications, the entire process can be automated, yielding reproducibly good results with significant time and cost savings. Information extraction consists of two stages, preprocessing and analysis. We focus here on the preprocessing stage, which typically involves several steps, such as calibration, background subtraction, baseline flattening, artifact removal, smoothing, and so on, before the resulting spectra can be further analyzed. Because the results of some of these steps can affect the performance of subsequent ones, attention must be given to the sequencing of steps, the compatibility of these sequences, and the propensity of each step to generate spectral distortions. We outline here important considerations to effect full automation of Raman spectral preprocessing: what is considered full automation; putative general principles to effect full automation; the proper sequencing of processing and analysis steps; conflicts and circularities arising from sequencing; and the need for, and approaches to, preprocessing quality control. These considerations are discussed and illustrated with biological and biomedical examples reflecting both successful and faulty preprocessing.
Mukherjee, Debdyuti; Gowda Y K, Guruprasada; Makri Nimbegondi Kotresh, Harish; Sampath, S
2017-06-14
Organic materials containing active carbonyl groups have attracted considerable attention as electrodes in Li-ion batteries due to their reversible redox activity, ability to retain capacity, and, in addition, their ecofriendly nature. Introduction of porosity will help accommodate as well as store small ions and molecules reversibly. In the present work, we introduce a mesoporous triptycene-related, rigid network polymer with high specific surface area as an electrode material for rechargeable Li-ion battery. The designed polymer with a three-dimensional (3D), rigid porous network allows free movement of ions/electrolyte as well as helps in interacting with the active anhydride moieties (containing two carbonyl groups). Considerable intake of Li + ions giving rise to very high specific capacity of 1100 mA h g -1 at a discharge current of 50 mA g -1 and ∼120 mA h g -1 at a high discharge current of 3 A g -1 are observed with excellent cyclability up to 1000 cycles. This remarkable rate capability, which is one of the highest among the reported organic porous polymers to date, makes the triptycene-related rigid 3D network a very good choice for Li-ion batteries and opens up a new method to design polymer-based electrode materials for metal-ion battery technology.
Personal Computer Based Controller For Switched Reluctance Motor Drives
NASA Astrophysics Data System (ADS)
Mang, X.; Krishnan, R.; Adkar, S.; Chandramouli, G.
1987-10-01
Th9, switched reluctance motor (SRM) has recently gained considerable attention in the variable speed drive market. Two important factors that have contributed to this are, the simplicity of construction and the possibility of developing low cost con-trollers with minimum number of switching devices in the drive circuits. This is mainly due to the state-of-art of the present digital circuits technology and the low cost of switching devices. The control of this motor drive is under research. Optimized performance of the SRM motor drive is very dependent on the integration of the controller, converter and the motor. This research on system integration involves considerable changes in the control algorithms and their implementation. A Personal computer (PC) based controller is very appropriate for this purpose. Accordingly, the present paper is concerned with the design of a PC based controller for a SRM. The PC allows for real-time microprocessor control with the possibility of on-line system parameter modifications. Software reconfiguration of this controller is easier than a hardware based controller. User friendliness is a natural consequence of such a system. Considering the low cost of PCs, this controller will offer an excellent cost-effective means of studying the control strategies for the SRM drive intop greater detail than in the past.
Tucha, O; Mecklinger, L; Laufkötter, R; Klein, H E; Walitza, S; Lange, K W
2006-10-01
The present study examined the effect of the stimulant medication methylphenidate (MPH) on attentional functioning of adults with ADHD. Sixteen adults with a diagnosed ADHD without comorbidity were assessed twice, at baseline off MPH and following MPH treatment. The assessment battery consisted of reaction time tasks of low complexity, including measures of alertness--subdivided into tonic and phasic alertness, vigilance, divided attention, flexibility and such aspects of selective attention as including focused attention, inhibition and integration of sensory information. In addition, 16 healthy participants who were matched to adults with ADHD according to sex, age, education level and intellectual functions were also assessed twice using the same test battery. The results of the present study suggest that adults with ADHD off stimulant medication are seriously impaired in various components of attention including vigilance, divided attention, selective attention and flexibility. These impairments of attention were observed primarily in regard to reaction time and its variability. Treatment of adults with ADHD using individually tailored doses of MPH has a positive effect on measures of alertness, vigilance, selective attention, divided attention and flexibility. However, even on MPH adults with ADHD displayed considerable deficits in vigilance and integration of sensory information. The present findings indicate that adults with ADHD are not differentially impaired in attentional processes but may suffer from a more global deficit of attention. Although MPH treatment has been found to be effective in the treatment of the attention deficit of adults with ADHD, additional treatment appears to be necessary.
Dai, Lengshi; Shinn-Cunningham, Barbara G
2016-01-01
Listeners with normal hearing thresholds (NHTs) differ in their ability to steer attention to whatever sound source is important. This ability depends on top-down executive control, which modulates the sensory representation of sound in the cortex. Yet, this sensory representation also depends on the coding fidelity of the peripheral auditory system. Both of these factors may thus contribute to the individual differences in performance. We designed a selective auditory attention paradigm in which we could simultaneously measure envelope following responses (EFRs, reflecting peripheral coding), onset event-related potentials (ERPs) from the scalp (reflecting cortical responses to sound) and behavioral scores. We performed two experiments that varied stimulus conditions to alter the degree to which performance might be limited due to fine stimulus details vs. due to control of attentional focus. Consistent with past work, in both experiments we find that attention strongly modulates cortical ERPs. Importantly, in Experiment I, where coding fidelity limits the task, individual behavioral performance correlates with subcortical coding strength (derived by computing how the EFR is degraded for fully masked tones compared to partially masked tones); however, in this experiment, the effects of attention on cortical ERPs were unrelated to individual subject performance. In contrast, in Experiment II, where sensory cues for segregation are robust (and thus less of a limiting factor on task performance), inter-subject behavioral differences correlate with subcortical coding strength. In addition, after factoring out the influence of subcortical coding strength, behavioral differences are also correlated with the strength of attentional modulation of ERPs. These results support the hypothesis that behavioral abilities amongst listeners with NHTs can arise due to both subcortical coding differences and differences in attentional control, depending on stimulus characteristics and task demands.
Does Language Matter? Exploring Chinese-Korean Differences in Holistic Perception.
Rhode, Ann K; Voyer, Benjamin G; Gleibs, Ilka H
2016-01-01
Cross-cultural research suggests that East Asians display a holistic attentional bias by paying attention to the entire field and to relationships between objects, whereas Westerners pay attention primarily to salient objects, displaying an analytic attentional bias. The assumption of a universal pan-Asian holistic attentional bias has recently been challenged in experimental research involving Japanese and Chinese participants, which suggests that linguistic factors may contribute to the formation of East Asians' holistic attentional patterns. The present experimental research explores differences in attention and information processing styles between Korean and Chinese speakers, who have been assumed to display the same attentional bias due to cultural commonalities. We hypothesize that the specific structure of the Korean language predisposes speakers to pay more attention to ground information than to figure information, thus leading to a stronger holistic attentional bias compared to Chinese speakers. Findings of the present research comparing different groups of English, Chinese, and Korean speakers provide further evidence for differences in East Asians' holistic attentional bias, which may be due to the influence of language. Furthermore, we also extend prior theorizing by discussing the potential impact of other cultural factors. In line with critical voices calling for more research investigating differences between cultures that are assumed to be culturally similar, we highlight important avenues for future studies exploring the language-culture relationship.
Evolution of the morphology of the river Dragonja (SW Slovenia) due to land-use changes
NASA Astrophysics Data System (ADS)
Keesstra, S. D.; van Huissteden, J.; Vandenberghe, J.; Van Dam, O.; de Gier, J.; Pleizier, I. D.
2005-07-01
The effects of increasing agricultural land use on fluvial morphology have received much attention in fluvial research. However, in several regions in Europe, a reversing trend of decreasing agricultural activity and land abandonment, followed by reforestation, is observed. The response of fluvial morphology deserves attention because of its large impacts on landscape and riverine habitats. With the help of geomorphological mapping, multi-date aerial photography and a range of dating techniques, we reconstructed the evolution of the morphology of the riverbed and the floodplain of the Dragonja river in southwestern Slovenia. The results of this study show that the fluvial morphology in this Mediterranean catchment has changed considerably as a result of shifts in agricultural land use, in particular large-scale land abandonment in the second half of the 20th century. Until the first half of the 19th century, floodplain aggradation prevailed. Probably around 1870, a large erosion event occurred from which the floodplain did not fully recover. A terrace standing 2.5 m above the present floodplain was formed. Natural reforestation, due to depopulation since World War II, caused a reduction in discharge and sediment supply to the river. The decreased intensity and frequency of floods allowed invasion of the riverbed by vegetation, causing narrowing and incision of the riverbed. This resulted in the formation of a terrace, which now stands 1.5 m above the present-day river. This terrace is about 60 years old. However, the largest increase in forest area occurred since 1975, which intensified this process of riverbed narrowing and incision, creating a local terrace at 0.5 m at 0.5 m above the presently meandering river.
Green Synthesis of Nanocrystals and Nanocomposites
Metal nanomaterials have attracted considerable attention because of their unique magnetic, optical, electrical, and catalytic properties and their potential applications in nanoelectronics as well as in various wet chemical synthesis methods. There is also great interest in synt...
21 CFR 14.27 - Determination to close portions of advisory committee meetings.
Code of Federal Regulations, 2011 CFR
2011-04-01
... protocols and procedures for a class of drugs or devices; consideration of labeling requirements for a class... brought to their attention, the person will be required to leave the meeting immediately. This inadvertent...
Pathology of trauma attributed to restraint systems in crash impacts.
DOT National Transportation Integrated Search
1969-02-01
Considerable attention has been focused on the sophisticated restraint and ejection protection of rigidly selected occupants of military aircraft and manned space vehicles. However, the vast majority of occupants of military and both civil transport ...
Aeronautical record : no. 1 (to June, 1923)
NASA Technical Reports Server (NTRS)
1923-01-01
"...considerations have prompted us to pay special attention to the development of aeronautical industries and aerial navigation as a commercial enterprise and to publish an analytical review of events in the aeronautical world and of the attendant problems."
Synthesis and characterization of polyaniline coated gold nanocomposites
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zuber, Siti Nurzulaiha Mohd; Kamarun, Dzaraini; Zaki, Hamizah
2015-08-28
Considerable attention has been drawn during the last two decades to prepare nanocomposites consists of conducting polymer and noble metal due to their potential ability to generate a new class of material with novel optical, chemical, electronic or mechanical properties for various applications. In this work, an attempt has been made to synthesize nanocomposite of polyaniline (PANI) coated with gold nanoparticles (AuNPs) chemically with various types of surfactants such as polyvinylpyrrolidone (PVP), and sodium dodecyl sulphate (SDS) which act as stabilizing agents to help in stabilization of the PANI/Gold nanocomposites system. The synthesized nanocomposites were characterized by UV-Visible, field emissionmore » scanning electron microscope (FESEM) and particle size analyzer (PSA). The formation of finger like structure can be seen in the FESEM images when the AuNPs were incorporated into the polymer matrix. The EDX data showed that 18.66% and 12.67% of AuNPs atoms were present in the composite system thus proved the incorporation of AuNPs into the polymer matrix. A small red shift of the absorption peak in the UV-Vis of both PANI/AuNPs composites system may be due to the incorporation of AuNPs in the PANI matrix.« less
Injury rate in a helicopter underwater escape trainer (HUET) from 2005-2012.
Brooks, Christopher J; MacDonald, Conor V; Gibbs, Peter N A
2014-08-01
Helicopter underwater escape training (HUET) carries a potential for injury and this paper identifies the injury rate. A marine survival training school registry of all students trained between 2005-2012 in HUET and the coinciding accident records were examined. There were 8902 students trained in a helicopter underwater escape simulator for a total of 59,245 underwater escapes. There were 40 cases where only first-aid was required and 3 serious injuries (a laceration requiring 5 sutures, 1 dislocated shoulder, and 1 water aspiration requiring hospitalization). There were no deaths and no problems reported with using the Emergency Breathing System (EBS) or Air Pocket. Of the injuries, 11 were due to the student using a poor escape technique. The overall probability of injury was 0.74 per 1000 ascents. In HUET training, there is a very low injury rate with almost no significant severity. Although not scientifically proven, this would suggest that the low incident rate is due to good medical screening and the attention given by instructors to anxious students. Compared to other training such as diving, parachute jumping, and submarine escape training, the rate of injury was considerably lower.
Toward a Fault Tolerant Architecture for Vital Medical-Based Wearable Computing.
Abdali-Mohammadi, Fardin; Bajalan, Vahid; Fathi, Abdolhossein
2015-12-01
Advancements in computers and electronic technologies have led to the emergence of a new generation of efficient small intelligent systems. The products of such technologies might include Smartphones and wearable devices, which have attracted the attention of medical applications. These products are used less in critical medical applications because of their resource constraint and failure sensitivity. This is due to the fact that without safety considerations, small-integrated hardware will endanger patients' lives. Therefore, proposing some principals is required to construct wearable systems in healthcare so that the existing concerns are dealt with. Accordingly, this paper proposes an architecture for constructing wearable systems in critical medical applications. The proposed architecture is a three-tier one, supporting data flow from body sensors to cloud. The tiers of this architecture include wearable computers, mobile computing, and mobile cloud computing. One of the features of this architecture is its high possible fault tolerance due to the nature of its components. Moreover, the required protocols are presented to coordinate the components of this architecture. Finally, the reliability of this architecture is assessed by simulating the architecture and its components, and other aspects of the proposed architecture are discussed.
Creation of wettability contrast patterns on metallic surfaces via pen drawn masks
NASA Astrophysics Data System (ADS)
Choi, Won Tae; Yang, Xiaolong; Breedveld, Victor; Hess, Dennis W.
2017-12-01
Micropatterned surfaces with wettability contrast have attracted considerable attention due to potential applications in 2D microfluidics, bioassays, and water harvesting. A simple method to develop wettability contrast patterns on metallic surfaces by using a commercial marker is described. A marker-drawn ink pattern on a copper surface displays chemical resistance to an aqueous solution of sodium bicarbonate and ammonium persulfate, thereby enabling selective nanowire growth in areas where ink is absent. Subsequent ink removal by an organic solvent followed by fluorocarbon film deposition yields a stable hydrophobic/super-hydrophobic patterned copper surface. Using this approach, hydrophobic dot and line patterns were constructed. The adhesion force of water droplets to the dots was controlled by adjusting pattern size, thus enabling controlled droplet transfer between two surfaces. Anisotropy of water droplet adhesion to line patterns can serve as a basis for directional control of water droplet motion. This general approach has also been employed to generate wettability contrast on aluminum surfaces, thereby demonstrating versatility. Due to its simplicity, low cost, and virtual independence of solid surface material, ink marker pens can be employed to create wettability patterns for a variety of applications, in fields as diverse as biomedicine and energy.
van Zyl, Winschau F.; Deane, Shelly M.
2015-01-01
Lactic acid bacteria (LAB) are natural inhabitants of the gastrointestinal tract (GIT) of humans and animals, and some LAB species receive considerable attention due to their health benefits. Although many papers have been published on probiotic LAB, only a few reports have been published on the migration and colonization of the cells in the GIT. This is due mostly to the lack of efficient reporter systems. In this study, we report on the application of the fluorescent mCherry protein in the in vivo tagging of the probiotic strains Enterococcus mundtii ST4SA and Lactobacillus plantarum 423. The mCherry gene, encoding a red fluorescent protein (RFP), was integrated into a nonfunctional region on the genome of L. plantarum 423 by homologous recombination. In the case of E. mundtii ST4SA, the mCherry gene was cloned into the pGKV223D LAB/Escherichia coli expression vector. Expression of the mCherry gene did not alter the growth rate of the two strains and had no effect on bacteriocin production. Both strains colonized the cecum and colon of mice. PMID:26116681
Neurocognitive Consequences of Sleep Deprivation
Goel, Namni; Rao, Hengyi; Durmer, Jeffrey S.; Dinges, David F.
2012-01-01
Sleep deprivation is associated with considerable social, financial, and health-related costs, in large measure because it produces impaired cognitive performance due to increasing sleep propensity and instability of waking neurobehavioral functions. Cognitive functions particularly affected by sleep loss include psychomotor and cognitive speed, vigilant and executive attention, working memory, and higher cognitive abilities. Chronic sleep-restriction experiments—which model the kind of sleep loss experienced by many individuals with sleep fragmentation and premature sleep curtailment due to disorders and lifestyle—demonstrate that cognitive deficits accumulate to severe levels over time without full awareness by the affected individual. Functional neuroimaging has revealed that frequent and progressively longer cognitive lapses, which are a hallmark of sleep deprivation, involve distributed changes in brain regions including frontal and parietal control areas, secondary sensory processing areas, and thalamic areas. There are robust differences among individuals in the degree of their cognitive vulnerability to sleep loss that may involve differences in prefrontal and parietal cortices, and that may have a basis in genes regulating sleep homeostasis and circadian rhythms. Thus, cognitive deficits believed to be a function of the severity of clinical sleep disturbance may be a product of genetic alleles associated with differential cognitive vulnerability to sleep loss. PMID:19742409
Resveratrol—Potential Antibacterial Agent against Foodborne Pathogens
Ma, Dexter S. L.; Tan, Loh Teng-Hern; Chan, Kok-Gan; Yap, Wei Hsum; Pusparajah, Priyia; Chuah, Lay-Hong; Ming, Long Chiau; Khan, Tahir Mehmood; Lee, Learn-Han; Goh, Bey-Hing
2018-01-01
Bacterial foodborne pathogens are a significant health burden and the recent emergence of pathogenic resistant strains due to the excessive use of antibiotics makes it more difficult to effectively treat infections as a result of contaminated food. Awareness of this impending health crisis has spurred the search for alternative antimicrobials with natural plant antimicrobials being among the more promising candidates as these substances have good acceptability and likely low toxicity levels as they have long been used in traditional medicines. Resveratrol (3,5,4′-trihydroxystilbene) is a naturally occurring stilbenoid which has been gaining considerable attention in medical field due to its diverse biological activities - it has been reported to exhibit antioxidant, cardioprotective, anti-diabetic, anticancer, and antiaging properties. Given that resveratrol is phytoalexin, with increased synthesis in response to infection by phytopathogens, there has been interest in exploring its antimicrobial activity. This review aims to provide an overview of the published data on the antibacterial activity of resveratrol against foodborne pathogens, its mechanisms of action as well as its possible applications in food packing and processing; in addition we also summarize the current data on its potential synergism with known antibacterials and future research and applications. PMID:29515440
NASA Astrophysics Data System (ADS)
Wang, Peng; Zong, Lanlan; Guan, Zhongjie; Li, Qiuye; Yang, Jianjun
2018-02-01
An economic and effective Pt-based alloy cocatalyst has attracted considerable attention due to their excellent catalytic activity and reducing Pt usage. In this study, PtNi alloy cocatalyst was successfully decorated on the g-C3N4/GO hybrid photocatalyst via a facile chemical reduction method. The Eosin Y-sensitized g-C3N4/PtNi/GO-0.5% composite photocatalyst yields about 1.54 and 1178 times higher hydrogen evolution rate than the Eosin Y-sensitized g-C3N4/Pt/GO-0.5% and g-C3N4/Ni/GO-0.5% samples, respectively. Mechanism of enhanced performance for the g-C3N4/PtNi/GO composite was also investigated by different characterization, such as photoluminescence, transient photocurrent response, and TEM. These results indicated that enhanced charge separation efficiency and more reactive sites are responsible for the improved hydrogen evolution performance due to the positive synergetic effect between Pt and Ni. This study suggests that PtNi alloy can be used as an economic and effective cocatalyst for hydrogen evolution reaction. [Figure not available: see fulltext.
Yamanaka, Toshiro; Nakagawa, Hiroe; Tsubouchi, Shigetaka; Domi, Yasuhiro; Doi, Takayuki; Abe, Takeshi; Ogumi, Zempachi
2017-03-09
Lithium-ion batteries have attracted considerable attention due to their high power density. The change in concentration of salt in the electrolyte solution in lithium-ion batteries during operation causes serious degradation of battery performance. Herein, a new method of in situ Raman spectroscopy with ultrafine multifiber probes was developed to simultaneously study the concentrations of ions at several different positions in the electrolyte solution in deep narrow spaces between the electrodes in batteries. The total amount of ions in the electrolyte solution clearly changed during operation due to the low permeability of the solid-electrolyte interphase (SEI) at the anode for Li + permeation. The permeability, which is a key factor to achieve high battery performance, was improved (enhanced) by adding film-forming additives to the electrolyte solution to modify the properties of the SEI. The results provide important information for understanding and predicting phenomena occurring in a battery and for designing a superior battery. The present method is useful for analysis in deep narrow spaces in other electrochemical devices, such as capacitors. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Lead poisoning in precious metals refinery assayers: a failure to notify workers at high risk.
Kern, D G
1994-05-01
Lead poisoning in a precious metals refinery fire assayer and a routine OSHA inspection prompted an investigation of the index facility, a survey of the industry, and efforts to notify assayers of this previously unrecognized hazard. Air and blood samples were obtained at the index facility. Management personnel from all fire assay laboratories in Rhode Island and southern Massachusetts were interviewed. The industry's trade association, OSHA, NIOSH, trade unions, and the media were asked to assist in a nationwide notification effort. Assayers at the index facility had excessive exposures to lead due to an age-old, lead-based assaying method that remains the industry gold standard. Blood lead levels of the three assayers (mean 61.3 micrograms/dl, range 48-86 micrograms/dl) were considerably higher than those of 16 other refinery workers (mean 27.4 micrograms/dl, range 13-49 micrograms/dl). The industry survey revealed inadequate knowledge of both the lead hazard and the applicability of the OSHA lead standard. Notification efforts failed in large part due to economic obstacles. The notification of workers at high risk of lead exposure and the eradication of occupational lead poisoning will require greater attention to economic forces.
Adsorption mechanism of SF6 decomposed species on pyridine-like PtN3 embedded CNT: A DFT study
NASA Astrophysics Data System (ADS)
Cui, Hao; Zhang, Xiaoxing; Chen, Dachang; Tang, Ju
2018-07-01
Metal-Nx embedded CNT have aroused considerable attention in the field of gas interaction due to their strong catalytic behavior, which provides prospective scopes for gas adsorption and sensing. Detecting SF6 decomposed species in certain devices is essential to guarantee their safe operation. In this work, we performed DFT method and simulated the adsorption of three SF6 decomposed gases (SO2, SOF2 and SO2F2) onto the PtN3 embedded CNT surface, in order to shed light on its adsorption ability and sensing mechanism. Results suggest that the CNT embedded with PtN3 center has strong interaction with these gas molecules, leading to high hybridization between Pt dopant and active atoms inner gas molecules. These interactions are assumed to be chemisorption due to the remarkable Ead and QT, thus resulting in dramatic deformations in electronic structure of PtN3-CNT near the Fermi level. Furthermore, the electronic redistribution cause the conductivity increase of proposed material in three systems, based on frontier molecular orbital theory. Our calculations attempt to suggest novel sensing material that are potentially employed in detection of SF6 decomposed components.
Polyunsaturated Fatty Acids in Lipid Bilayers and Tubules
NASA Astrophysics Data System (ADS)
Hirst, Linda S.; Yuan, Jing; Pramudya, Yohannes; Nguyen, Lam T.
2007-03-01
Omega-3 polyunsaturated fatty acids (PUFAs) are found in a variety of biological membranes and have been implicated with lipid raft formation and possible function, typical molecules include DHA (Docosahexanoic Acid) and AA (Alphalinoleic Acid) which have been the focus of considerable attention in recent years. We are interested in the phase behavior of these molecules in the lipid bilayer. The addition of lipid molecules with polyunsaturated chains has a clear effect on the fluidity and curvature of the membrane and we investigate the effects the addition of polyunsaturated lipids on bilayer structure and tubule formation. Self-assembled cylindrical lipid tubules have attracted considerable attention because of their interesting structures and potential technological applications. Using x-ray diffraction techniques, Atomic Force Microscopy and confocal fluorescence imaging, both symmetric and mixed chain lipids were incorporated into model membranes and the effects on bilayer structure and tubule formation investigated.
Centuries of thermal sea-level rise due to anthropogenic emissions of short-lived greenhouse gases
Zickfeld, Kirsten
2017-01-01
Mitigation of anthropogenic greenhouse gases with short lifetimes (order of a year to decades) can contribute to limiting warming, but less attention has been paid to their impacts on longer-term sea-level rise. We show that short-lived greenhouse gases contribute to sea-level rise through thermal expansion (TSLR) over much longer time scales than their atmospheric lifetimes. For example, at least half of the TSLR due to increases in methane is expected to remain present for more than 200 y, even if anthropogenic emissions cease altogether, despite the 10-y atmospheric lifetime of this gas. Chlorofluorocarbons and hydrochlorofluorocarbons have already been phased out under the Montreal Protocol due to concerns about ozone depletion and provide an illustration of how emission reductions avoid multiple centuries of future TSLR. We examine the “world avoided” by the Montreal Protocol by showing that if these gases had instead been eliminated in 2050, additional TSLR of up to about 14 cm would be expected in the 21st century, with continuing contributions lasting more than 500 y. Emissions of the hydrofluorocarbon substitutes in the next half-century would also contribute to centuries of future TSLR. Consideration of the time scales of reversibility of TSLR due to short-lived substances provides insights into physical processes: sea-level rise is often assumed to follow air temperature, but this assumption holds only for TSLR when temperatures are increasing. We present a more complete formulation that is accurate even when atmospheric temperatures are stable or decreasing due to reductions in short-lived gases or net radiative forcing. PMID:28069937
Centuries of thermal sea-level rise due to anthropogenic emissions of short-lived greenhouse gases.
Zickfeld, Kirsten; Solomon, Susan; Gilford, Daniel M
2017-01-24
Mitigation of anthropogenic greenhouse gases with short lifetimes (order of a year to decades) can contribute to limiting warming, but less attention has been paid to their impacts on longer-term sea-level rise. We show that short-lived greenhouse gases contribute to sea-level rise through thermal expansion (TSLR) over much longer time scales than their atmospheric lifetimes. For example, at least half of the TSLR due to increases in methane is expected to remain present for more than 200 y, even if anthropogenic emissions cease altogether, despite the 10-y atmospheric lifetime of this gas. Chlorofluorocarbons and hydrochlorofluorocarbons have already been phased out under the Montreal Protocol due to concerns about ozone depletion and provide an illustration of how emission reductions avoid multiple centuries of future TSLR. We examine the "world avoided" by the Montreal Protocol by showing that if these gases had instead been eliminated in 2050, additional TSLR of up to about 14 cm would be expected in the 21st century, with continuing contributions lasting more than 500 y. Emissions of the hydrofluorocarbon substitutes in the next half-century would also contribute to centuries of future TSLR. Consideration of the time scales of reversibility of TSLR due to short-lived substances provides insights into physical processes: sea-level rise is often assumed to follow air temperature, but this assumption holds only for TSLR when temperatures are increasing. We present a more complete formulation that is accurate even when atmospheric temperatures are stable or decreasing due to reductions in short-lived gases or net radiative forcing.
Disciplining Bioethics: Towards a Standard of Methodological Rigor in Bioethics Research
Adler, Daniel; Shaul, Randi Zlotnik
2012-01-01
Contemporary bioethics research is often described as multi- or interdisciplinary. Disciplines are characterized, in part, by their methods. Thus, when bioethics research draws on a variety of methods, it crosses disciplinary boundaries. Yet each discipline has its own standard of rigor—so when multiple disciplinary perspectives are considered, what constitutes rigor? This question has received inadequate attention, as there is considerable disagreement regarding the disciplinary status of bioethics. This disagreement has presented five challenges to bioethics research. Addressing them requires consideration of the main types of cross-disciplinary research, and consideration of proposals aiming to ensure rigor in bioethics research. PMID:22686634
Oil, oil dispersants and related substances in the marine environment
NASA Astrophysics Data System (ADS)
Gunkel, W.; Gassmann, G.
1980-03-01
Of all substances threatening life in the seas, oil has received by far the most attention from the public, administrators, politicians and scientists. The main reasons for this are: (1) even limited amounts of oil are easily visible; (2) oil can exert obvious negative effects, e. g. extensive damage to birds and other animals, impairment of the recreational value of beaches and marinas, losses in fisheries due to tainting of catches and rejection by the public of seafood from areas known to have been recently polluted. In addition, dramatic tanker accidents are widely publicized. During the last decade tens of thousands of papers have been published about the impact of oil on the marine environment, and we are well informed about most basic facts, such as input and fate of oil, toxicity to adult organisms and recolonization. Due to considerable sophistication of analytical techniques, especially the introduction of glass-capillary gas chromatography, we are well aware that recently formed biogenic hydrocarbons by far extend the input directly due to pollution. Large gaps exist in our knowledge about sedimentation and transport of weathered oil, natural degradation rates, and the flow of hydrocarbons through the food web. Relatively little is known about the influence of oil and dispersants upon complex ecosystems. The often mentioned suspicion of increased cancer probability in humans due to seafood contaminated by hydrocarbons has not been substantiated; in fact, it seems unlikely that such an effect exists. By far the greatest uncertainty about potential oil impact concerns possible negative effects of hydrocarbons on chemical communication mechanisms between organisms. Intensive studies of behaviour scientists working with concentrations far below the toxic level are needed in fisheries biology, zoology and botany. Most cases of oil contamination known thus far have been limited in space and time; the oil has turned out to be degradable by natural processes. Such oil pollution neither endangers nor considerably impairs the future of mankind. In future research, more than anything else, objective critical evaluation and careful quantification are needed.
Special problems in aerosol delivery: neonatal and pediatric considerations.
Cole, C H
2000-06-01
Identification of the determinants of efficient aerosol delivery and the specific challenges of aerosol delivery to infants and children can facilitate a systematic approach to optimize aerosol delivery to this population. There are inherent anatomical, physiologic, pathophysiologic, and technical limitations of aerosol efficiency in infants and young children. Nevertheless, one can enhance aerosol efficiency through application of sound principles of aerosol delivery and by exerting control over factors that are amenable to intervention. Improvements in aerosol formulations and delivery systems are being made that will enhance efficiency, decrease risk, and reduce waste and cost. Attention to aerosol particle size (1-3 microm mass median aerodynamic diameter and geometric standard deviation < 2 microm), and the concentration of this respirable particle fraction produced by an aerosol system may enhance delivery through endotracheal tubes and to the lower respiratory tract in infants and children with low V(T) and low inspiratory rates. Attention to the choice of delivery system and to details of proper MDI technique (shaking, priming, immediate actuation, and avoiding multiple actuations prior to inhalation), choice of the aerosol spacer and patient interface (type of face mask, endotracheal tube, mouthpiece), spacer cleaning, and consideration of the medicine to be aerosolized (solution or suspension, viscosity) permit adjustment of the aerosol regimen to optimize delivery. All the patient-related, system-related, and operator-dependent considerations combined can greatly impact aerosol delivery efficacy and improve therapeutic response. Therefore, education and motivation of medical personnel, parents and caregivers, and patients regarding factors that influence aerosol efficiency and teaching of proper technique must be prioritized in order to improve aerosol delivery. Aerosol therapy to all patients, especially infants and young children, would be well served if we had a clear understanding of the efficiency and functional differences among the various drugs and devices. These are substantive issues with daily therapeutic impact that have received increasingly outspoken concern over the past decade by aerosol scientists and clinicians. These issues must be given due attention by drug and device manufacturers as well as by regulatory agencies. The medication, the device, and the conditions under which they are tested must be considered together and studied as thoroughly as the medications themselves with respect to total output and particle size distribution. As noted by Bisgaard, medication dose recommendations are useless unless the device and technique used are specified. Medication dose recommendation could be facilitated by setting equivalent standards for generic and brand-name medications and devices. In addition, standardization of in vitro models with better replicas of infants' and children's anatomy (oropharynx, upper airways), and better in vitro lung models, plus utilization of realistic breathing patterns of infants and children will improve in vitro prediction of the in vivo dose delivered to lower airways. This would greatly facilitate selection of delivery systems under specific circumstances for infants and children of various ages). Safety profile, therapeutic efficacy, and efficiency of aerosolized medications delivered to infants and children need to be rigorously studied. This is particularly true for medications with potentially great benefit but possible adverse effects, such as inhaled glucocorticoid therapy in extremely premature infants. Common sense, ethics, and due respect for the same high standard of approval requirements of adults and older children should motivate further research in understanding and improving aerosol delivery in infants and young children.
Heidari, Mohammad Hassan; Porghasem, Mohsen; Mirzaei, Nazanin; Mohseni, Jafar Hesam; Heidari, Matine; Azargashb, Eznollah; Movafagh, Abolfazl; Heidari, Reihane; Molouki, Aidin; Larijani, Leila
2014-02-01
Since several high level natural radiation areas (HLNRAs) exist on our planet, considerable attention has been drawn to health issues that may develop as the result of visiting or living in such places. City of Ramsar in Iran is an HNLRA, and is a tourist attraction mainly due to its hot spas. However, the growing awareness over its natural radiation sources has prompted widespread scientific investigation at national level. In this study, using an ELISA method, the level of expression of three tumor markers known as carcinoembryonic antigen (CEA), prostate-specific antigen (PSA) and carcino antigen 19-9 (CA19-9) in blood serum of 40 local men of Ramsar (subject group) was investigated and compared to 40 men from the city of Noshahr (control group). Noshahr was previously identified as a normal level natural radiation area (NLNRA) that is some 85 km far from Ramsar. According to statistical analysis, there was a significant difference in the levels of PSA and CA19-9 markers between the two groups (p < 0.001) with those of Ramsar being considerably higher. CEA level did not show any difference. Although some of the volunteers tested positive to the markers, they were in good health as confirmed by the physician. Moreover, the high number of positive markers in Noshahr was considerable. Therefore, future study is needed to further validate this result and to determine the level of positivity to tumor markers in both cities. Copyright © 2013 Elsevier Ltd. All rights reserved.
Helping adolescents with attention-deficit/ hyperactivity disorder transition toward adulthood.
Gotlieb, Edward M; Gotlieb, Jaquelin S
2009-04-01
Pediatricians can help adolescents with attention-deficit/hyperactivity disorder prepare to enter post-high school training and the workforce. In this article peer-reviewed studies and other resources for informing patients of the issues ahead are identified. We discuss preventive counseling, including long-term monitoring, adherence to treatment, driving, tobacco, alcohol, and other drug usage, career planning, and intimacy. The current status of insurance coverage for young adults and federal programs to assist students with attention-deficit/hyperactivity disorder are reviewed also. Consideration is given for applying for precollege testing and college accommodations and traveling abroad with medications. Pediatricians and young adults are directed to Web-based and other self-management information and tools.
The tightrope between drawing media attention and exaggeration
NASA Astrophysics Data System (ADS)
Savenije, Hubert H. G.
2017-04-01
To draw media attention, it is not sufficient to present your research in a simple and understandable way. The message should also be news-worthy, controversial or surprising. Unfortunately well-balanced, well-founded and considerate statements are seldom attractive to the media. The media want something that creates commotion. This may tempt one to overstate the impact of research results, or to exaggerate its relevance. But this is dangerous, because if you do manage to draw the attention of the media, then the headline maker will surely make your claim bolder then you intended it to be. I had to learn this the hard way. I'll illustrate this with a few examples from my own media experience.
Effect of group walking traffic on dynamic properties of pedestrian structures
NASA Astrophysics Data System (ADS)
Shahabpoor, E.; Pavic, A.; Racic, V.; Zivanovic, S.
2017-01-01
The increasing number of reported vibration serviceability problems in newly built pedestrian structures, such as footbridges and floors, under walking load has attracted considerable attention in the civil engineering community over the past two decades. The key design challenges are: the inter- and intra-subject variability of walking people, the unknown mechanisms of their interaction with the vibrating walking surfaces and the synchronisation between individuals in a group. Ignoring all or some of these factors makes the current design methods an inconsistent approximation of reality. This often leads to considerable over- or under-estimation of the structural response, yielding an unreliable assessment of vibration performance. Changes to the dynamic properties of an empty structure due to the presence of stationary people have been studied extensively over the past two decades. The understanding of the similar effect of walking people on laterally swaying bridges has improved tremendously in the past decade, due to considerable research prompted by the Millennium Bridge problem. However, there is currently a gap in knowledge about how moving pedestrians affect the dynamic properties of vertically vibrating structures. The key reason for this gap is the scarcity of credible experimental data pertinent to moving pedestrians on vertically vibrating structures, especially for multi-pedestrian traffic. This paper addresses this problem by studying the dynamic properties of the combined human-structure system, i.e. occupied structure damping ratio, natural frequency and modal mass. This was achieved using a comprehensive set of frequency response function records, measured on a full-scale test structure, which was occupied by various numbers of moving pedestrians under different walking scenarios. Contrary to expectations, it was found that the natural frequency of the joint moving human-structure system was higher than that of the empty structure, while it was lower when the same people were standing still. The damping ratio of the joint human-structure system was considerably higher than that of the empty structure for both the walking and standing people - in agreement with previous reports for stationary people - and was more prominent for larger groups. Interestingly, it was found that the walking human-structure system has more damping compared with the equivalent standing human-structure system. The properties of a single degree of freedom mass-spring-damper system representing a moving crowd needed to replicate these observations have been identified.
Terry, Alvin V.; Callahan, Patrick M.; Beck, Wayne D.; Vandenhuerk, Leah; Sinha, Samantha; Bouchard, Kristy; Schade, Rose; Waller, Jennifer L.
2014-01-01
Organophosphate (OP)-based chemicals are used worldwide for many purposes and they have likely saved millions of people from starvation and disease. However, due to their toxicity they can also pose a significant environmental risk. While considerable research has focused on the acute symptoms and long-term consequences of overtly toxic exposures to OPs, less attention has been given to the subject of repeated exposures to levels that are not associated with acute symptoms (subthreshold exposures). There is clinical evidence indicating that this type of OP exposure can lead to prolonged deficits in cognition; however only a few studies have addressed this issue prospectively in animal models. In this study, repeated subthreshold exposures to the OP nerve agent diisopropylfluorophosphate (DFP) were evaluated in a 5-Choice Serial Reaction Time Task (5C-SRTT), an animal model of sustained attention. Adult rats were trained to stably perform the 5C-SRTT and then injected subcutaneously with vehicle or DFP 0.5 mg/kg every other day for 30 days. Behavioral testing occurred daily during the DFP-exposure period and throughout a 45 day (OP-free) washout period. Compared to vehicle-treated controls, DFP-treated rats exhibited deficits in accuracy, increases in omissions and timeout responses during the OP exposure period, while no significant effects on premature responses, perseverative responses, or response latencies were noted. While the increase in timeout responses remained detectible during washout, all other DFP-related alterations in 5C-SRTT performance abated. When the demands of the task were increased by the presentation of variable intertrial intervals, premature responses were also elevated in DFP-treated rats during the washout period. These results indicate that repeated exposures to subthreshold doses of DFP lead to reversible impairments in sustained attention as well as persistent impairments of inhibitory response control in rats. PMID:24819591
Objective assessment of attention in delirium: a narrative review.
Tieges, Zoë; Brown, Laura J E; MacLullich, Alasdair M J
2014-12-01
Inattention is a core feature of delirium, and valid assessment of attention is central to diagnosis. Methods of measuring attention in delirium can be divided into two broad categories: (i) objective neuropsychological testing; and (ii) subjective grading of behaviour during interview and clinical examination. Here, we review and critically evaluate studies of objective neuropsychological testing of attention in delirium. We examine the implications of these studies for delirium detection and monitoring in clinical practice and research, and how these studies inform understanding of the nature of attentional deficits in delirium. Searches of MEDLINE and ISI Web of Knowledge databases were performed to identify studies in which objective tests of attention had been administered to patients with delirium, who had been diagnosed using DSM or ICD criteria. Sixteen publications were identified. The attention tests administered in these studies were grouped into the following categories: measures of attention span, vigilance tests, other pen-and-paper tests (e.g. Trail Making Test) and computerised tests of speeded reaction, vigilance and sustained attention. Patients with delirium showed deficits on all tasks, although most tasks were not considered pure measures of attention. Five papers provided data on differential diagnosis from dementia. Cancellation tests, spatial span tests and computerised tests of sustained attention discriminated delirium from dementia. Five studies presented reliability or validity statistics. The existing evidence base on objective assessment of attention in delirium is small. Objective testing of attention is underdeveloped but shows considerable promise in clinical practice and research. Copyright © 2014 John Wiley & Sons, Ltd.
Attentional Bias in Human Category Learning: The Case of Deep Learning.
Hanson, Catherine; Caglar, Leyla Roskan; Hanson, Stephen José
2018-01-01
Category learning performance is influenced by both the nature of the category's structure and the way category features are processed during learning. Shepard (1964, 1987) showed that stimuli can have structures with features that are statistically uncorrelated (separable) or statistically correlated (integral) within categories. Humans find it much easier to learn categories having separable features, especially when attention to only a subset of relevant features is required, and harder to learn categories having integral features, which require consideration of all of the available features and integration of all the relevant category features satisfying the category rule (Garner, 1974). In contrast to humans, a single hidden layer backpropagation (BP) neural network has been shown to learn both separable and integral categories equally easily, independent of the category rule (Kruschke, 1993). This "failure" to replicate human category performance appeared to be strong evidence that connectionist networks were incapable of modeling human attentional bias. We tested the presumed limitations of attentional bias in networks in two ways: (1) by having networks learn categories with exemplars that have high feature complexity in contrast to the low dimensional stimuli previously used, and (2) by investigating whether a Deep Learning (DL) network, which has demonstrated humanlike performance in many different kinds of tasks (language translation, autonomous driving, etc.), would display human-like attentional bias during category learning. We were able to show a number of interesting results. First, we replicated the failure of BP to differentially process integral and separable category structures when low dimensional stimuli are used (Garner, 1974; Kruschke, 1993). Second, we show that using the same low dimensional stimuli, Deep Learning (DL), unlike BP but similar to humans, learns separable category structures more quickly than integral category structures. Third, we show that even BP can exhibit human like learning differences between integral and separable category structures when high dimensional stimuli (face exemplars) are used. We conclude, after visualizing the hidden unit representations, that DL appears to extend initial learning due to feature development thereby reducing destructive feature competition by incrementally refining feature detectors throughout later layers until a tipping point (in terms of error) is reached resulting in rapid asymptotic learning.
Structural and geophysical interpretation of Roatan Island, Honduras, Western Caribbean
NASA Astrophysics Data System (ADS)
Sutton, Daniel Scott
Roatan Island is the largest of the Bay Islands of Honduras. These islands form an emergent crest off the Caribbean coast of Honduras called the Bonacca Ridge. The Bartlett Trough to the north and subsequent Bonacca Ridge were likely formed due to the transform fault system of the Motagua-Swan Islands Fault System. This fault system forms the tectonic plate boundary between the North American and Caribbean plates. Although the timing and kinematics are poorly constrained, the Bay Islands and the Bonacca Ridge were likely uplifted due to transpression along this left-lateral strike-slip system. With limited regional exposures along the adjacent tectonic boundary, this study aimed to present a structural interpretation for Roatan. This new interpretation is further explained through regional considerations for a suggested geologic history of the northwestern Caribbean. In order to better constrain the kinematics of uplift and exhumation of Roatan Island, structural, gravity, and magnetic surveys were conducted. Principal attention was directed to the structural relationship between the geologic units and their relationship to one another through deformation. Resulting geologic cross-sections from this study present the metamorphic basement exposed throughout the island to be in a normal structural order consisting of biotite schist and gneiss, with overlying units of chlorite schist, carbonate, and conglomerate. These units have relatively concordant strike and dip measurements, consistent with resultant magnetic survey readings. Additionally, large and irregular bodies of amphibolite and serpentinite throughout the island are interpreted to have been emplaced as mafic and ultra-mafic intrusions in weakness zones along Early Paleogene transform system fault planes. The interpretation and suggested geologic history from this study demonstrate the importance of transpressive tectonics both local to Roatan and regionally throughout geologic history. Consideration of this interpretation will help to further constrain regional studies over the northwestern Caribbean.
Feldthusen, Caroline; Björk, Mathilda; Forsblad-d'Elia, Helena; Mannerkorpi, Kaisa
2013-05-01
The aim of this study was to describe how persons with rheumatoid arthritis (RA) of working age experience and handle their fatigue in everyday life. Six focus group discussions were conducted focusing on experiences of fatigue in 25 persons with RA (19 women, 6 men), aged 20-60 years. The discussions were recorded, transcribed verbatim, and analyzed according to qualitative content analysis. The analyses resulted in four categories. (1) Perception of fatigue: Fatigue was experienced different from normal tiredness, unpredictable, and overwhelming. It was associated with negative emotions, changed self-image, and fears. Feelings of frustration and shame were central when the persons were forced to omit valued life activities. (2) Consequences due to fatigue: The fatigue caused changes in cognitive ability, ability to act, and overall activity pattern where the increased need for rest and sleep caused an imbalance in daily life. The participants struggled not to let the fatigue interfere with work. The fatigue also brought negative consequences for their significant others. (3) Communicating fatigue: Fatigue was difficult to gain understanding for, and the participants adjusted their communication accordingly; it was important to keep up appearances. During medical consultation, fatigue was perceived as a factor not given much consideration, and the participants expressed taking responsibility for managing their fatigue symptoms themselves. (4) Strategies to handle fatigue: Strategies comprised conscious self-care, mental strategies, planning, and prioritizing. Fatigue caused considerable health problems for persons with RA of working age: negative emotions, imbalance in daily life due to increased need for rest, and difficulties gaining understanding. This draws attention to the importance of developing new modes of care to address fatigue in RA. Person-centered care to improve balance in life may be one approach needing further investigations.
NASA Astrophysics Data System (ADS)
Luna-Pineda, Tatiana; Soto-Feliciano, Kristina; De La Cruz-Montoya, Edwin; Pacheco Londoño, Leonardo C.; Ríos-Velázquez, Carlos; Hernández-Rivera, Samuel P.
2007-04-01
FTIR, Raman spectroscopy and Surface Enhanced Raman Scattering (SERS) requires a minimum of sample allows fast identification of microorganisms. The use of this technique for characterizing the spectroscopic signatures of these agents and their stimulants has recently gained considerable attention due to the fact that these techniques can be easily adapted for standoff detection from considerable distances. The techniques also show high sensitivity and selectivity and offer near real time detection duty cycles. This research focuses in laying the grounds for the spectroscopic differentiation of Staphylococcus spp., Pseudomonas spp., Bacillus spp., Salmonella spp., Enterobacter aerogenes, Proteus mirabilis, Klebsiella pneumoniae, and E. coli, together with identification of their subspecies. In order to achieve the proponed objective, protocols to handle, cultivate and analyze the strains have been developed. Spectroscopic similarities and marked differences have been found for Spontaneous or Normal Raman spectra and for SERS using silver nanoparticles have been found. The use of principal component analysis (PCA), discriminate factor analysis (DFA) and a cluster analysis were used to evaluate the efficacy of identifying potential threat bacterial from their spectra collected on single bacteria. The DFA from the bacteria Raman spectra show a little discrimination between the diverse bacterial species however the results obtained from the SERS demonstrate to be high discrimination technique. The spectroscopic study will be extended to examine the spores produced by selected strains since these are more prone to be used as Biological Warfare Agents due to their increased mobility and possibility of airborne transport. Micro infrared spectroscopy as well as fiber coupled FTIR will also be used as possible sensors of target compounds.
Effective Affective Design for Distance Education.
ERIC Educational Resources Information Center
Zvacek, Susan M.
1991-01-01
Discusses the importance of affective considerations when designing instruction for distance education. Topics discussed include learner motivation based on Keller's ARCS model (Attention, Relevance, Confidence, and Satisfaction); communication patterns that facilitate interaction between students; and ethics involved with marketing programs,…
Microwave-Assisted Green Synthesis of Silver Nanostructures
This account summarizes a microwave (MW)-assisted synthetic approach for producing silver nanostructures. The rapid and in-core MW heating has received considerable attention as a promising new method for the one-pot synthesis of metallic nanostructures in solutions. Conceptually...
Service-Learning in the Mathematical Sciences
ERIC Educational Resources Information Center
Hadlock, Charles R.
2013-01-01
Service-learning can be a valuable educational enterprise with both course-specific and general education benefits, as well as contributions to the community. These potential merits and key considerations in achieving them are discussed with special attention to the mathematical sciences.
POWER TO DETECT REGIONAL TRENDS IN HABITAT CHARACTERISTICS
The condition of stream habitat draws considerable attention concerning the protection and recovery of salmonid populations in the West. Habitat degradation continues and substantial sums of money are spent on habitat restoration. However, aided by uncertainty concerning the ad...
POWER TO DETECT REGIONAL TRENDS IN PHYSICAL HABITAT
The condition of stream habitat draws considerable attention concerning the protection and recovery of salmonid populations in the West. Habitat degradation continues and substantial sums of money are spent on habitat restoration. However, aided by uncertainty concerning the ad...
Patterns of physiological activity accompanying performance on a perceptual-motor task.
DOT National Transportation Integrated Search
1969-04-01
Air traffic controllers are required to spend considerable periods of time observing radar displays. Yet, information regarding physiological measures which best reflect the attentional process in complex vigilance tasks is generally lacking. As an i...
Teaching Probability: A Socio-Constructivist Perspective
ERIC Educational Resources Information Center
Sharma, Sashi
2015-01-01
There is a considerable and rich literature on students' misconceptions in probability. However, less attention has been paid to the development of students' probabilistic thinking in the classroom. This paper offers a sequence, grounded in socio-constructivist perspective for teaching probability.
Affective associations with negativity: Why popular peers attract youths' visual attention.
Lansu, Tessa A M; Troop-Gordon, Wendy
2017-10-01
Visual attention to high-status peers is well documented, but whether this attentional bias is due to high-status individuals' leadership and prosocial characteristics or due to their more agonistic behaviors has yet to be examined. To identify the affective associations that may underlie visual attention for high-status versus low-status peers, 122 early adolescents (67 girls; M age =11.0years, SD=0.7) completed a primed attention paradigm. Visual attention was measured using eye tracking as participants looked simultaneously at photographs of two classmates: one nominated by peers as popular and one nominated by peers as unpopular. Prior to each trial, the early adolescents were presented with a positive prime, the word "nice"; a negative prime, the word "stupid"; or no prime. Primary analyses focused on first-gaze preference and total gaze time The results showed a stronger first gaze preference for popular peers than for unpopular peers in the no-prime and negative prime trials than in the positive prime trials. The visual preference for a popular peer, thus, was attenuated by the positive prime. These findings are consistent with the notion that youths may visually attend to high-status peers due to their association with more negative characteristics and the threat they may pose to youths' own social standing and ability to gain interpersonal resources. Copyright © 2017 Elsevier Inc. All rights reserved.
Automatic Mechanisms for Social Attention Are Culturally Penetrable.
Cohen, Adam S; Sasaki, Joni Y; German, Tamsin C; Kim, Heejung S
2017-01-01
Are mechanisms for social attention influenced by culture? Evidence that social attention is triggered automatically by bottom-up gaze cues and is uninfluenced by top-down verbal instructions may suggest it operates in the same way everywhere. Yet considerations from evolutionary and cultural psychology suggest that specific aspects of one's cultural background may have consequence for the way mechanisms for social attention develop and operate. In more interdependent cultures, the scope of social attention may be broader, focusing on more individuals and relations between those individuals. We administered a multi-gaze cueing task requiring participants to fixate a foreground face flanked by background faces and measured shifts in attention using eye tracking. For European Americans, gaze cueing did not depend on the direction of background gaze cues, suggesting foreground gaze alone drives automatic attention shifting; for East Asians, cueing patterns differed depending on whether the foreground cue matched or mismatched background cues, suggesting foreground and background gaze information were integrated. These results demonstrate that cultural background influences the social attention system by shifting it into a narrow or broad mode of operation and, importantly, provides evidence challenging the assumption that mechanisms underlying automatic social attention are necessarily rigid and impenetrable to culture. Copyright © 2015 Cognitive Science Society, Inc.
Spatial attention, feature-based attention and saccades: Three sides of one coin?
Mazer, James A.
2013-01-01
The last three decades has seen a steady growth of neuroscience research aimed at understanding the functions and sources of top-down attentional modulation in the brain. This correlates with recognition that attention may be a necessary component of sensory systems to support natural behaviors in natural environments. Complexity and clutter are two of the most recognizable hallmarks of natural environments, which can simultaneously contain vitally important and completely irrelevant stimuli. Attention serves as an adaptive filter allowing each sensory modality preferential processing routes for important stimuli while suppressing responses to distracters, thus optimizing use of limited neural resources. In other words, “attention” is the family of mechanisms by which organisms are able to effectively and selectively allocate limited neural resources to achieve specific behavioral goals. This review provides some historical context for considering attentional frameworks and modern neurophysiological attention research, focusing on visual attention. A taxonomy of common attentional effects and neural mechanisms is provided, along with consideration of the specific relationship between attention and saccade planning. We examine the validity of premotor theories of attention, which posit that attention and saccade planning are one and the same. While there is strong evidence that attention and oculomotor planning are similar, with shared neural substrates, there is also evidence that these two functions are not synonymous. Finally, we examine neurophysiological explanations for dysfunction in Attention Deficit Hyperactivity Disorder (ADHD) and the hypothesis that social impairment in Autism Spectrum Disorders (ASD) is partially attributable to perturbations of attentional control circuitry. PMID:21529782
NASA Astrophysics Data System (ADS)
Shoshany, Maxim
2017-04-01
Shrublands cover a total of 12.7 million km2 , a considerable part of them along semi-arid to arid transition zones. Varying patterns of shrubs, grasses and barren land along such climatic gradients express the spatial dimension of climate change and human disturbance which attracted limited attention in the eco-geomorphic literature. Questions concerning relationships between rainfall, shrublands biomass and their patterns are fundamental for the understanding of these ecosystems response to the expected changes in water availability due to global warming and the increase in human disturbance to natural ecosystems following World population growth. While processes leading to the formation of patterns had attracted considerable attention, the spatial dimension of Water Use Efficiency (WUE) which is a parameter measuring ecosystems productivity in relation to water availability is severely missing. Relative shrub cover is a primary estimator of the fraction of water utilized for shrubs growth. Edge effects must be considered as well in fragmented ecosystems in general and in hot regions in particular since soil temperature in hot regions which frequently exceed 50oC during summer months decreases photosynthesis and productivity in plants bordering bare soil. This edge effect is decreasing with the increase in shrubs' height. Pattern Water Use Efficiency describes the combined effect of shrub cover, shrub height and shrub patches edge zone proportion on water use efficiency. In my presentation I will first present mapping od PWUEs across Mediterranean to arid transition zones in the Eastern Mediterranean. Then I will present several mathematical models describing PWUE for simulated patterns, searching for the spatial parameterization providing the highest sensitivity to patterns responses to changes in habitat conditions. Such simulations would allow us to discuss several PWUE strategies for shrublands recovery under the current scenarios of climate change and human driven degradation.
Making health care safer: What is the contribution of health psychology?
Vincent, Charles; Wearden, Alison; French, David P
2015-11-01
While health care brings great benefits, all treatments, and many investigations, carry some risk. As patients, we should be told of the risks of specific treatments but we are also at risk from failings in the health care system itself. We suggest that, while there are many examples of individual health psychologists who have made important contributions, this has not yet translated into a broader disciplinary engagement. Health psychologists have devoted much more attention to patients and devoted much less attention to the potentially huge impact of studying and intervening with staff, clinical practice, and organizations. We believe that there are considerable opportunities for health psychology to engage more closely with patient safety and, more importantly, that this would be of great benefit to both patients and staff. Statement of contribution What is already known on this subject? While health care brings great benefits, all treatments, and many investigations, carry some risk. Patients are also at risk from failings in the health care system itself. Studies using review of medical records in many countries have found that between 8% and 12% of patients in hospital suffer an unintended harm due to health care. What does this study add? There are many examples of individual psychologists who have made important contributions, but this has not yet translated into a broader disciplinary engagement. There are considerable opportunities for health psychology to engage more closely with patient safety. These include health behaviour change, teamwork, communication after medical error, diagnosis and decision making, organisational culture, and improving compliance with rules and standards. Psychologists providing a clinical service to specialist services in any area could expand their remit from supporting patients to a more general support and engagement with safety and quality initiatives. Health psychologists have models to understand the behaviour of people, and recent developments in changing behaviour should be applicable to health professionals in addition to their patients. © 2015 The British Psychological Society.
Xiao, Rui; Jiang, Diwei; Christakos, George; Fei, Xufeng; Wu, Jiaping
2016-01-01
Soil sealing (loss of soil resources due to extensive land covering for the purpose of house building, road construction etc.) and subsequent soil landscape pattern changes constitute typical environmental problems in many places worldwide. Previous studies concentrated on soil sealing in urbanized regions, whereas rural areas have not been given sufficient attention. Accordingly, this paper studies soil landscape pattern dynamics (i.e., landscape pattern changes in response to rural anthropogenic activities) in the Tiaoxi watershed (Zhejiang province, eastern China), in which surface sealing is by far the predominant component of human forcing with respect to environmental change. A novel approach of quantifying the impacts of rural anthropogenic activities on soil resources is presented. Specifically, quantitative relationships were derived between five soil landscape pattern metrics (patch density, edge density, shape index, Shannon’s diversity index and aggregation index) and three rural anthropogenic activity indicators (anthropogenic activity intensity, distance to towns, and distance to roads) at two landscape block scales (3 and 5 km) between 1985 and 2010. The results showed that the Tiaoxi watershed experienced extensive rural settlement expansion and high rates of soil sealing. Soil landscapes became more fragmented, more irregular, more isolated, and less diverse. Relationships between soil landscape pattern changes and rural anthropogenic activities differed with the scale (spatial and temporal) and variable considered. In particular, the anthropogenic activity intensity was found to be the most important indicator explaining social development intensity, whereas the other two proximity indicators had a significant impact at certain temporal interval. In combination with scale effects, spatial dependency (correlation) was shown to play a key role that should be carefully taken into consideration in any relevant environmental study. Overall, the findings of this work suggest that soil sealing can be a critical human forcing issue with considerable consequences deserving serious attention by the experts, the public and the government alike. PMID:27832167
Xiao, Rui; Jiang, Diwei; Christakos, George; Fei, Xufeng; Wu, Jiaping
2016-01-01
Soil sealing (loss of soil resources due to extensive land covering for the purpose of house building, road construction etc.) and subsequent soil landscape pattern changes constitute typical environmental problems in many places worldwide. Previous studies concentrated on soil sealing in urbanized regions, whereas rural areas have not been given sufficient attention. Accordingly, this paper studies soil landscape pattern dynamics (i.e., landscape pattern changes in response to rural anthropogenic activities) in the Tiaoxi watershed (Zhejiang province, eastern China), in which surface sealing is by far the predominant component of human forcing with respect to environmental change. A novel approach of quantifying the impacts of rural anthropogenic activities on soil resources is presented. Specifically, quantitative relationships were derived between five soil landscape pattern metrics (patch density, edge density, shape index, Shannon's diversity index and aggregation index) and three rural anthropogenic activity indicators (anthropogenic activity intensity, distance to towns, and distance to roads) at two landscape block scales (3 and 5 km) between 1985 and 2010. The results showed that the Tiaoxi watershed experienced extensive rural settlement expansion and high rates of soil sealing. Soil landscapes became more fragmented, more irregular, more isolated, and less diverse. Relationships between soil landscape pattern changes and rural anthropogenic activities differed with the scale (spatial and temporal) and variable considered. In particular, the anthropogenic activity intensity was found to be the most important indicator explaining social development intensity, whereas the other two proximity indicators had a significant impact at certain temporal interval. In combination with scale effects, spatial dependency (correlation) was shown to play a key role that should be carefully taken into consideration in any relevant environmental study. Overall, the findings of this work suggest that soil sealing can be a critical human forcing issue with considerable consequences deserving serious attention by the experts, the public and the government alike.
Race, racial resentment, attentiveness to the news media, and public opinion toward the Jena Six.
Goidel, Kirby; Parent, Wayne; Mann, Bob
2011-01-01
Objective. We outline the role of race, racial resentment, and attentiveness to news in structuring public opinion toward the prosecution of the Jena Six, the name given to six African-American high school students who beat a white student, five of whom were subsequently charged with attempted second-degree murder.Method. We rely on a telephone survey of 428 registered voters collected in the aftermath of the protests in Jena, Louisiana.Results. Public reactions were heavily filtered by race and associated with measures of racial resentment. African Americans followed news about the protests more closely, believed race was the most important consideration in the decision to prosecute, and believed the decision to prosecute was the wrong decision. Racially conservative white respondents were less likely to believe race was the most important consideration in the decision to prosecute and were more likely to believe that the decision to prosecute was the right decision. Consistent with theories of agenda setting and framing, attentiveness to the news influenced perceptions regarding the importance of race in the decision to prosecute but not whether the decision was the right decision.Conclusions. At least within the context of the Deep South, race and racial attitudes continue to be an important predictor of public reactions to racially charged events. Attentiveness to the news influenced the lens through which events were interpreted, but not perceptions of whether the outcome was the right decision.
Hamilton, Robert M; Rosenthal, Eric; Hulpke-Wette, Martin; Graham, John G I; Sergeant, Joseph
2012-02-01
Regulatory decisions regarding attention deficit hyperactivity disorder drug licensing and labelling, along with recent statements from professional associations, raise questions of practice regarding the evaluation and treatment of patients with attention deficit hyperactivity disorder. To address these issues for the European community, the European Network for Hyperkinetic Disorders, through its European Attention Deficit Hyperactivity Disorder Guidelines Group, organised a meeting between attention deficit hyperactivity disorder specialists, paediatric cardiovascular specialists, and representatives of the major market authorisation holders for attention deficit hyperactivity disorder medications. This manuscript represents their consensus on cardiovascular aspects of attention deficit hyperactivity disorder medications. Although sudden death has been identified in multiple young individuals on attention deficit hyperactivity disorder medication causing regulatory concern, when analysed for exposure using currently available data, sudden death does not appear to exceed that of the general population. There is no current evidence to suggest an incremental benefit to electrocardiography assessment of the general attention deficit hyperactivity disorder patient. Congenital heart disease patients have an increased prevalence of attention deficit hyperactivity disorder, and can benefit from attention deficit hyperactivity disorder therapies, including medication. The attention deficit hyperactivity disorder specialist is the appropriate individual to evaluate benefit and risk and recommend therapy in all patients, although discussion with a heart specialist is reasonable for congenital heart disease patients. For attention deficit hyperactivity disorder patients with suspected heart disease or risk factor/s for sudden death, assessment by a heart specialist is recommended, as would also be the case for a non-attention deficit hyperactivity disorder patient. The identification of risk factors for sudden death should not automatically exclude the use of attention deficit hyperactivity disorder medication.
The effects of selective and divided attention on sensory precision and integration.
Odegaard, Brian; Wozny, David R; Shams, Ladan
2016-02-12
In our daily lives, our capacity to selectively attend to stimuli within or across sensory modalities enables enhanced perception of the surrounding world. While previous research on selective attention has studied this phenomenon extensively, two important questions still remain unanswered: (1) how selective attention to a single modality impacts sensory integration processes, and (2) the mechanism by which selective attention improves perception. We explored how selective attention impacts performance in both a spatial task and a temporal numerosity judgment task, and employed a Bayesian Causal Inference model to investigate the computational mechanism(s) impacted by selective attention. We report three findings: (1) in the spatial domain, selective attention improves precision of the visual sensory representations (which were relatively precise), but not the auditory sensory representations (which were fairly noisy); (2) in the temporal domain, selective attention improves the sensory precision in both modalities (both of which were fairly reliable to begin with); (3) in both tasks, selective attention did not exert a significant influence over the tendency to integrate sensory stimuli. Therefore, it may be postulated that a sensory modality must possess a certain inherent degree of encoding precision in order to benefit from selective attention. It also appears that in certain basic perceptual tasks, the tendency to integrate crossmodal signals does not depend significantly on selective attention. We conclude with a discussion of how these results relate to recent theoretical considerations of selective attention. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
Problem Behaviors & Tourette Syndrome. Revised.
ERIC Educational Resources Information Center
Bruun, Ruth Dowling; And Others
This pamphlet discusses behavioral problems which are sometimes associated with Tourette Syndrome (TS), along with suggestions for parents to help manage these behaviors. Consideration is given to the following problems: obsessive-compulsive symptoms; attention deficit hyperactivity disorder; aggressive and explosive behaviors; self-injurious…
ERIC Educational Resources Information Center
Bennett, Mark
2011-01-01
This paper provides a brief overview of recent developmental research on themes related to children's social identities. Initially, consideration is given to the capacity for social categorization, following which attention is given to children's developing conceptions of social identities, their identification with social groups, and the…
Individual differences in selective attention predict speech identification at a cocktail party
Oberfeld, Daniel; Klöckner-Nowotny, Felicitas
2016-01-01
Listeners with normal hearing show considerable individual differences in speech understanding when competing speakers are present, as in a crowded restaurant. Here, we show that one source of this variance are individual differences in the ability to focus selective attention on a target stimulus in the presence of distractors. In 50 young normal-hearing listeners, the performance in tasks measuring auditory and visual selective attention was associated with sentence identification in the presence of spatially separated competing speakers. Together, the measures of selective attention explained a similar proportion of variance as the binaural sensitivity for the acoustic temporal fine structure. Working memory span, age, and audiometric thresholds showed no significant association with speech understanding. These results suggest that a reduced ability to focus attention on a target is one reason why some listeners with normal hearing sensitivity have difficulty communicating in situations with background noise. DOI: http://dx.doi.org/10.7554/eLife.16747.001 PMID:27580272
Visual question answering using hierarchical dynamic memory networks
NASA Astrophysics Data System (ADS)
Shang, Jiayu; Li, Shiren; Duan, Zhikui; Huang, Junwei
2018-04-01
Visual Question Answering (VQA) is one of the most popular research fields in machine learning which aims to let the computer learn to answer natural language questions with images. In this paper, we propose a new method called hierarchical dynamic memory networks (HDMN), which takes both question attention and visual attention into consideration impressed by Co-Attention method, which is the best (or among the best) algorithm for now. Additionally, we use bi-directional LSTMs, which have a better capability to remain more information from the question and image, to replace the old unit so that we can capture information from both past and future sentences to be used. Then we rebuild the hierarchical architecture for not only question attention but also visual attention. What's more, we accelerate the algorithm via a new technic called Batch Normalization which helps the network converge more quickly than other algorithms. The experimental result shows that our model improves the state of the art on the large COCO-QA dataset, compared with other methods.
2010-01-01
Background Polyunsaturated fatty acids are essential nutrients for humans. They are structural and functional components of cell membranes and pre-stages of the hormonally and immunologically active eicosanoids. Recent discoveries have shown that the long-chained omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) also play an important role in the central nervous system. They are essential for normal brain functioning including attention and other neuropsychological skills. Materials and methods In our large observational study we monitored 810 children from 5 to 12 years of age referred for medical help and recommended for consuming polyunsaturated fatty acids (PUFA) in combination with zinc and magnesium by a physician over a period of at least 3 months. The food supplement ESPRICO® (further on referred to as the food supplement) is developed on the basis of current nutritional science and containing a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc. Study objective was to evaluate the nutritional effects of the PUFA-zinc-magnesium combination on symptoms of attention deficit, impulsivity, and hyperactivity as well as on emotional problems and sleep related parameters. Assessment was performed by internationally standardised evaluation scales, i.e. SNAP-IV and SDQ. Tolerance (adverse events) and acceptance (compliance) of the dietary therapy were documented. Results After 12 weeks of consumption of a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc most subjects showed a considerable reduction in symptoms of attention deficit and hyperactivity/impulsivity assessed by SNAP-IV. Further, the assessment by SDQ revealed fewer emotional problems at the end of the study period compared to baseline and also sleeping disorders. Mainly problems to fall asleep, decreased during the 12 week nutritional therapy. Regarding safety, no serious adverse events occurred. A total of 16 adverse events with a possible causal relationship to the study medication were reported by 14 children (1.7%) and only 5.2% of the children discontinued the study due to acceptance problems. Continuation of consumption of the food supplement was recommended by the paediatricians for 61.1% of the children. Conclusion Our results suggest a beneficial effect of a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc consumption on attentional, behavioural, and emotional problems of children and adolescents. Thus, considering the behavioural benefit in combination with the low risk due to a good safety profile, the dietary supplementation with PUFA in combination with zinc and magnesium can be recommended. PMID:20868469
NASA Astrophysics Data System (ADS)
Velazquez, Antonio; Swartz, Raymond A.
2011-04-01
Wind turbine systems are attracting considerable attention due to concerns regarding global energy consumption as well as sustainability. Advances in wind turbine technology promote the tendency to improve efficiency in the structure that support and produce this renewable power source, tending toward more slender and larger towers, larger gear boxes, and larger, lighter blades. The structural design optimization process must account for uncertainties and nonlinear effects (such as wind-induced vibrations, unmeasured disturbances, and material and geometric variabilities). In this study, a probabilistic monitoring approach is developed that measures the response of the turbine tower to stochastic loading, estimates peak demand, and structural resistance (in terms of serviceability). The proposed monitoring system can provide a real-time estimate of the probability of exceedance of design serviceability conditions based on data collected in-situ. Special attention is paid to wind and aerodynamic characteristics that are intrinsically present (although sometimes neglected in health monitoring analysis) and derived from observations or experiments. In particular, little attention has been devoted to buffeting, usually non-catastrophic but directly impacting the serviceability of the operating wind turbine. As a result, modal-based analysis methods for the study and derivation of flutter instability, and buffeting response, have been successfully applied to the assessment of the susceptibility of high-rise slender structures, including wind turbine towers. A detailed finite element model has been developed to generate data (calibrated to published experimental and analytical results). Risk assessment is performed for the effects of along wind forces in a framework of quantitative risk analysis. Both structural resistance and wind load demands were considered probabilistic with the latter assessed by dynamic analyses.
Paradoxical Cross-Over Due to Attention to High or Low Spatial Frequencies
ERIC Educational Resources Information Center
Niemeier, Matthias; Stojanoski, Boge; Singh, Vaughan W. A.; Chu, Eddie
2008-01-01
The mechanisms underlying the right hemisphere's dominance for spatial and attentional functions lacks a comprehensively explanation. For example, perceptual biases, as observed in line bisection and related tasks, might be caused by an attentional asymmetry or by perceptual processes such as a specialization of the left and right hemisphere for…
ERIC Educational Resources Information Center
Fagioli, Sabrina; Macaluso, Emiliano
2009-01-01
Behavioral studies indicate that subjects are able to divide attention between multiple streams of information at different locations. However, it is still unclear to what extent the observed costs reflect processes specifically associated with spatial attention, versus more general interference due the concurrent monitoring of multiple streams of…
ERIC Educational Resources Information Center
Soveri, Anna; Laine, Matti; Hamalainen, Heikki; Hugdahl, Kenneth
2011-01-01
It has been claimed that due to their experience in controlling two languages, bilinguals exceed monolinguals in certain executive functions, especially inhibition of task-irrelevant stimuli. Here we investigated the effects of bilingualism on an executive phonological task, namely the forced-attention dichotic listening task with syllabic…
Paneri, Sofia; Gregoriou, Georgia G.
2017-01-01
The ability to select information that is relevant to current behavioral goals is the hallmark of voluntary attention and an essential part of our cognition. Attention tasks are a prime example to study at the neuronal level, how task related information can be selectively processed in the brain while irrelevant information is filtered out. Whereas, numerous studies have focused on elucidating the mechanisms of visual attention at the single neuron and population level in the visual cortices, considerably less work has been devoted to deciphering the distinct contribution of higher-order brain areas, which are known to be critical for the employment of attention. Among these areas, the prefrontal cortex (PFC) has long been considered a source of top-down signals that bias selection in early visual areas in favor of the attended features. Here, we review recent experimental data that support the role of PFC in attention. We examine the existing evidence for functional specialization within PFC and we discuss how long-range interactions between PFC subregions and posterior visual areas may be implemented in the brain and contribute to the attentional modulation of different measures of neural activity in visual cortices. PMID:29033784
Paneri, Sofia; Gregoriou, Georgia G
2017-01-01
The ability to select information that is relevant to current behavioral goals is the hallmark of voluntary attention and an essential part of our cognition. Attention tasks are a prime example to study at the neuronal level, how task related information can be selectively processed in the brain while irrelevant information is filtered out. Whereas, numerous studies have focused on elucidating the mechanisms of visual attention at the single neuron and population level in the visual cortices, considerably less work has been devoted to deciphering the distinct contribution of higher-order brain areas, which are known to be critical for the employment of attention. Among these areas, the prefrontal cortex (PFC) has long been considered a source of top-down signals that bias selection in early visual areas in favor of the attended features. Here, we review recent experimental data that support the role of PFC in attention. We examine the existing evidence for functional specialization within PFC and we discuss how long-range interactions between PFC subregions and posterior visual areas may be implemented in the brain and contribute to the attentional modulation of different measures of neural activity in visual cortices.
Differences in children's thinking and learning during attentional focus instruction.
Perreault, Melanie E; French, Karen E
2016-02-01
Considerable evidence supports the motor learning advantage associated with an external focus of attention; however, very few studies have investigated attentional focus effects with children despite individual functional constraints that have the potential to impact use of instructional content. Thus, the purpose of this study was to determine the effect of attentional focus instruction on motor learning in children. Participants (n=42) aged 9-11years were randomly assigned to one of three gender-stratified groups: (1) control, (2) internal focus, or (3) external focus. Following initial instructions and task demonstration, participants performed 100 modified free throws over two days while receiving additional cues respective to their attentional focus condition and returned approximately 48h later to perform 20 additional free throws. Results revealed no significant learning differences between groups. However, responses to retrospective verbal reports suggest that the use of external focus content during practice may have contributed to some participants' superior performance in retention. Future research should continue to examine attentional focus effects across a variety of ages and incorporate retrospective verbal reports in order to examine children's thoughts during attentional focus instruction. Copyright © 2015 Elsevier B.V. All rights reserved.
Navya, P N; Daima, Hemant Kumar
2016-01-01
Innovative engineered nanomaterials are at the leading edge of rapidly emerging fields of nanobiotechnology and nanomedicine. Meticulous synthesis, unique physicochemical properties, manifestation of chemical or biological moieties on the surface of materials make engineered nanostructures suitable for a variety of biomedical applications. Besides, tailored nanomaterials exhibit entirely novel therapeutic applications with better functionality, sensitivity, efficiency and specificity due to their customized unique physicochemical and surface properties. Additionally, such designer made nanomaterials has potential to generate series of interactions with various biological entities including DNA, proteins, membranes, cells and organelles at nano-bio interface. These nano-bio interactions are driven by colloidal forces and predominantly depend on the dynamic physicochemical and surface properties of nanomaterials. Nevertheless, recent development and atomic scale tailoring of various physical, chemical and surface properties of nanomaterials is promising to dictate their interaction in anticipated manner with biological entities for biomedical applications. As a result, rationally designed nanomaterials are in extensive demand for bio-molecular detection and diagnostics, therapeutics, drug and gene delivery, fluorescent labelling, tissue engineering, biochemical sensing and other pharmaceuticals applications. However, toxicity and risk associated with engineered nanomaterials is rather unclear or not well understood; which is gaining considerable attention and the field of nanotoxicology is evolving promptly. Therefore, this review explores current knowledge of articulate engineering of nanomaterials for biomedical applications with special attention on potential toxicological perspectives.
NASA Astrophysics Data System (ADS)
Navya, P. N.; Daima, Hemant Kumar
2016-02-01
Innovative engineered nanomaterials are at the leading edge of rapidly emerging fields of nanobiotechnology and nanomedicine. Meticulous synthesis, unique physicochemical properties, manifestation of chemical or biological moieties on the surface of materials make engineered nanostructures suitable for a variety of biomedical applications. Besides, tailored nanomaterials exhibit entirely novel therapeutic applications with better functionality, sensitivity, efficiency and specificity due to their customized unique physicochemical and surface properties. Additionally, such designer made nanomaterials has potential to generate series of interactions with various biological entities including DNA, proteins, membranes, cells and organelles at nano-bio interface. These nano-bio interactions are driven by colloidal forces and predominantly depend on the dynamic physicochemical and surface properties of nanomaterials. Nevertheless, recent development and atomic scale tailoring of various physical, chemical and surface properties of nanomaterials is promising to dictate their interaction in anticipated manner with biological entities for biomedical applications. As a result, rationally designed nanomaterials are in extensive demand for bio-molecular detection and diagnostics, therapeutics, drug and gene delivery, fluorescent labelling, tissue engineering, biochemical sensing and other pharmaceuticals applications. However, toxicity and risk associated with engineered nanomaterials is rather unclear or not well understood; which is gaining considerable attention and the field of nanotoxicology is evolving promptly. Therefore, this review explores current knowledge of articulate engineering of nanomaterials for biomedical applications with special attention on potential toxicological perspectives.
Effect of hydrophobic environments on the hypothesized liquid-liquid critical point of water.
Strekalova, Elena G; Corradini, Dario; Mazza, Marco G; Buldyrev, Sergey V; Gallo, Paola; Franzese, Giancarlo; Stanley, H Eugene
2012-01-01
The complex behavior of liquid water, along with its anomalies and their crucial role in the existence of life, continue to attract the attention of researchers. The anomalous behavior of water is more pronounced at subfreezing temperatures and numerous theoretical and experimental studies are directed towards developing a coherent thermodynamic and dynamic framework for understanding supercooled water. The existence of a liquid-liquid critical point in the deep supercooled region has been related to the anomalous behavior of water. However, the experimental study of supercooled water at very low temperatures is hampered by the homogeneous nucleation of the crystal. Recently, water confined in nanoscopic structures or in solutions has attracted interest because nucleation can be delayed. These systems have a tremendous relevance also for current biological advances; e.g., supercooled water is often confined in cell membranes and acts as a solvent for biological molecules. In particular, considerable attention has been recently devoted to understanding hydrophobic interactions or the behavior of water in the presence of apolar interfaces due to their fundamental role in self-assembly of micelles, membrane formation and protein folding. This article reviews and compares two very recent computational works aimed at elucidating the changes in the thermodynamic behavior in the supercooled region and the liquid-liquid critical point phenomenon for water in contact with hydrophobic environments. The results are also compared to previous reports for water in hydrophobic environments.
Spatial attention can modulate unconscious orientation processing.
Bahrami, Bahador; Carmel, David; Walsh, Vincent; Rees, Geraint; Lavie, Nilli
2008-01-01
It has recently been suggested that visual spatial attention can only affect consciously perceived events. We measured the effects of sustained spatial attention on orientation-selective adaptation to gratings, rendered invisible by prolonged interocular suppression. Spatial attention augmented the orientation-selective adaptation to invisible adaptor orientation. The effect of attention was clearest for test stimuli at peri-threshold, intermediate contrast levels, suggesting that previous negative results were due to assessing orientation discrimination at maximum contrast. On the basis of these findings we propose a constrained hypothesis for the difference between neuronal mechanisms of spatial attention in the presence versus absence of awareness.
Attention-Deficit Hyperactivity Disorder.
ERIC Educational Resources Information Center
Barkley, Russell A.
1998-01-01
Attention deficit hyperactivity disorder (ADHD) may arise when key brain circuits do not develop properly, perhaps due to an altered gene or genes. Describes ADHD in detail and introduces a psychological model of ADHD. (ASK)
Attention and memory evaluation across the life span: heterogeneous effects of age and education.
Gómez-Pérez, Esther; Ostrosky-Solís, Feggy
2006-05-01
The developmental sequences of attention and memory were studied by utilizing normative data derived from the neuropsychological battery named NEUROPSI ATTENTION AND MEMORY. A sample of 521 Spanish-speaking individuals, aged 6 to 85 years, participated in this study. In the adult sample, educational level ranged from 0 to 22 years of education. Data from subtests measuring orientation, attention and concentration, executive functions, working memory, immediate and delayed verbal memory, and immediate and delayed visual memory were included. The factor structure of the analyzed battery is presented. The effects of age and education on this structure were analyzed. Results suggested that although attention and memory are related, their developmental sequences are separated from one another. During childhood, the development of selective and sustained attention, attentional-working memory, and executive functions showed a fast improvement in performance. Development of verbal memory and place and person orientation showed a slower increment in scores. In the adult sample it was found that factors related to memory are sensitive to age, whereas those related to attention and executive functions are sensitive to education. The consideration of both the developmental sequence, as well as differential effects of education, can improve the sensitivity and specificity of neuropsychological measures, allowing early diagnosis of cognitive dysfunction and implementation of adequate rehabilitation programs.
Posttraumatic stress disorder and fear of emotions: the role of attentional control.
Sippel, Lauren M; Marshall, Amy D
2013-06-01
Individuals with posttraumatic stress disorder (PTSD) experience elevated concerns about their capacity to control, and the consequences of, strong emotions that occur in response to trauma reminders. Anxiety is theorized to compromise attentional control (Eysenck, Derakshan, Santos, & Calvo, 2007). In turn, diminished attentional control may increase vulnerability to threat cues and emotional reactivity (Ehlers & Clark, 2001). Consequently, attentional control may play a role in the fear of emotions frequently experienced by individuals with PTSD. Study participants included 64 men and 64 women with a mean age of 37 years, 86% of whom were White, non-Hispanic. Participants experienced an average of 7.68 types of traumatic events, most commonly including motor vehicle accidents and intimate partner violence. PTSD symptoms positively correlated with fear of emotions (r = .53) and negatively correlated with attentional control (r = -.38). Attentional control was negatively correlated with fear emotions (r = -.77) and partially mediated the link between PTSD and fear of emotions (R(2) = .22). Given the findings regarding top-down attentional control, these results have implications for cognitive and emotional processing theories of PTSD and emphasize the importance of clinical consideration of fear of emotions and attentional control in the treatment of PTSD. Copyright © 2013 International Society for Traumatic Stress Studies.
Küntay, Aylin C; Ozyürek, Asli; Planck, Max
2006-05-01
Pragmatic development requires the ability to use linguistic forms, along with non-verbal cues, to focus an interlocutor's attention on a referent during conversation. We investigate the development of this ability by examining how the use of demonstratives is learned in Turkish, where a three-way demonstrative system (bu, su, o) obligatorily encodes both distance contrasts (i.e. proximal and distal) and absence or presence of the addressee's visual attention on the referent. A comparison of the demonstrative use by Turkish children (6 four- and 6 six-year-olds) and 6 adults during conversation shows that adultlike use of attention directing demonstrative, su, is not mastered even at the age of six, while the distance contrasts are learned earlier. This language specific development reveals that designing referential forms in consideration of recipient's attentional status during conversation is a pragmatic feat that takes more than six years to develop.
Colzato, Lorenza S; van der Wel, Pauline; Sellaro, Roberta; Hommel, Bernhard
2016-01-01
Recent studies show that a single bout of meditation can impact information processing. We were interested to see whether this impact extends to attentional focusing and the top-down control over irrelevant information. Healthy adults underwent brief single bouts of either focused attention meditation (FAM), which is assumed to increase top-down control, or open monitoring meditation (OMM), which is assumed to weaken top-down control, before performing a global-local task. While the size of the global-precedence effect (reflecting attentional focusing) was unaffected by type of meditation, the congruency effect (indicating the failure to suppress task-irrelevant information) was considerably larger after OMM than after FAM. Our findings suggest that engaging in particular kinds of meditation creates particular cognitive-control states that bias the individual processing style toward either goal-persistence or cognitive flexibility. Copyright © 2015 Elsevier Inc. All rights reserved.
Fadardi, Javad Salehi; Cox, W Miles; Rahmani, Arash
2016-01-01
The present chapter first argues how having a goal for procuring alcohol or other substances leads to the development of a time-binding, dynamic, and goal oriented motivational state termed current concern, as the origin of substance-related attentional bias. Next, it discusses the importance of attentional bias in the development, continuation of, and relapsing to substance abuse. It further proceeds with a review of selective evidence from cognitive psychology that helps account for making decisions about using an addictive substance or refraining from using it. A discussion on the various brain loci that are involved in attentional bias and other kinds of cue reactivity is followed by presenting findings from neurocognitive research. Finally, from an interdisciplinary perspective, the chapter presents new trends and ideas that can be applied to addiction-related cognitive measurement and training. © 2016 Elsevier B.V. All rights reserved.
Tracking the location of visuospatial attention in a contingent capture paradigm.
Leblanc, Emilie; Prime, David J; Jolicoeur, Pierre
2008-04-01
Currently, there is considerable controversy regarding the degree to which top-down control can affect attentional capture by salient events. According to the contingent capture hypothesis, attentional capture by a salient stimulus is contingent on a match between the properties of the stimulus and top-down attentional control settings. In contrast, bottom-up saliency accounts argue that the initial capture of attention is determined solely by the relative salience of the stimulus, and the effect of top-down attentional control is limited to effects on the duration of attentional engagement on the capturing stimulus. In the present study, we tested these competing accounts by utilizing the N2pc event-related potential component to track the locus of attention during an attentional capture task. The results were completely consistent with the contingent capture hypothesis: An N2pc wave was elicited only by distractors that possessed the target-defining attribute. In a second experiment, we expanded upon this finding by exploring the effect of target-distractor similarity on the duration that attention dwells at the distractor location. In this experiment, only distractors possessing the target-defining attribute (color) captured visuospatial attention to their location and the N2pc increased in duration and in magnitude when the capture distractor also shared a second target attribute (category membership). Finally, in three additional control experiments, we replicated the finding of an N2pc generated by distractors, only if they shared the target-defining attribute. Thus, our results demonstrate that attentional control settings influence both which stimuli attract attention and to what extent they are processed.
Parasites of freshwater fishes in North America: why so neglected?
Scholz, Tomáš; Choudhury, Anindo
2014-02-01
Fish parasitology has a long tradition in North America and numerous parasitologists have contributed considerably to the current knowledge of the diversity and biology of protistan and metazoan parasites of freshwater fishes. The Journal of Parasitology has been essential in disseminating this knowledge and remains a significant contributor to our understanding of fish parasites in North America as well as more broadly at the international level. However, with a few exceptions, the importance of fish parasites has decreased during the last decades, which is reflected in the considerable decline of funding and corresponding decrease of attention paid to these parasites in Canada and the United States of America. After the 'golden age' in the second half of the 20th Century, fish parasitology in Canada and the United States went in a new direction, driven by technology and a shift in priorities. In contrast, fish parasitology in Mexico has undergone rapid development since the early 1990s, partly due to extensive international collaboration and governmental funding. A critical review of the current data on the parasites of freshwater fishes in North America has revealed considerable gaps in the knowledge of their species composition, host specificity, life cycles, evolution, phylogeography, and relationships with their fish hosts. As to the key question, "Why so neglected?" this is probably because: (1) fish parasites are not in the forefront due to their lesser economic importance; (2) there is little funding for this kind of research, especially if a practical application is not immediately apparent; and (3) of shifting interests and a shortage of key personalities to train a new generation (they switched to marine habitats or other fields). Some of the opportunities for future research are outlined, such as climate change and cryptic species diversity. A significant problem challenging future research seems to be the loss of trained and experienced fish parasitologists. This has 2 major ramifications: the loss of expertise in identifying organisms that other biologists (e.g., ecologists, molecular biologists, evolutionists) work with, and an incomplete comprehension of ecosystem structure and function in the face of climate change, emerging diseases, and loss of biodiversity.
Braboszcz, Claire; Cahn, B. Rael; Balakrishnan, Bhavani; Maturi, Raj K.; Grandchamp, Romain; Delorme, Arnaud
2013-01-01
Meditation has lately received considerable interest from cognitive neuroscience. Studies suggest that daily meditation leads to long lasting attentional and neuronal plasticity. We present changes related to the attentional systems before and after a 3 month intensive meditation retreat. We used three behavioral psychophysical tests - a Stroop task, an attentional blink task, and a global-local letter task-to assess the effect of Isha yoga meditation on attentional resource allocation. 82 Isha yoga practitioners were tested at the beginning and at the end of the retreat. Our results showed an increase in correct responses specific to incongruent stimuli in the Stroop task. Congruently, a positive correlation between previous meditation experience and accuracy to incongruent Stroop stimuli was also observed at baseline. We also observed a reduction of the attentional blink. Unexpectedly, a negative correlation between previous meditation experience and attentional blink performance at baseline was observed. Regarding spatial attention orientation as assessed using the global-local letter task, participants showed a bias toward local processing. Only slight differences in performance were found pre- vs. post- meditation retreat. Biasing toward the local stimuli in the global-local task and negative correlation of previous meditation experience with attentional blink performance is consistent with Isha practices being focused-attention practices. Given the relatively small effect sizes and the absence of a control group, our results do not allow clear support nor rejection of the hypothesis of meditation-driven neuronal plasticity in the attentional system for Isha yoga practice. PMID:24376429
Countertransference in the family therapy of survivors of sexual abuse.
Shay, J J
1992-01-01
As family therapy of sexual abuse survivors has become more common, theoretical and technical issues have received considerable attention. Less attention has been devoted to the countertransference experience of the therapist. Unexamined therapist countertransference is a critical element in the treatment of these families, which markedly influences the nature and direction of treatment. Particular types of countertransference are presented here. In addition, the contention is made that countertransference is not only evoked by the particular presentation of the family members, but also by the therapist's unexplored political and moral beliefs.
Environmental considerations influencing dietary choices: exploring consumer attitudes
USDA-ARS?s Scientific Manuscript database
Introduction: With increasing focus on anthropogenic causes of climate change, more attention is on the contribution of food systems. Public discourse on sustainability leads consumers to consider how they may reduce environmental damage with personal dietary decisions. US-based studies evaluating p...
Environmental Argumentation as Sociocultural Activity
ERIC Educational Resources Information Center
Oliveira, Alandeom W.; Akerson, Valarie L.; Oldfield, Martha
2012-01-01
While environmental argumentation has recently received much attention from science educators, little consideration has been given to how personal identities and social relationships can either support or constrain student argumentation. This study attends to this issue by examining environmental argumentation as a sociocultural activity (how…
Universal Design: Process, Principles, and Applications
ERIC Educational Resources Information Center
Burgstahler, Sheryl
2009-01-01
Designing any product or environment involves the consideration of many factors, including aesthetics, engineering options, environmental issues, safety concerns, industry standards, and cost. Typically, designers focus their attention on the average user. In contrast, universal design (UD), according to the Center for Universal Design," is…
DESIGN AND EVALUATION OF BENCH-SCALE COMPOST TREATMENT SYSTEM FOR HAZARDOUS WASTE
Soil bound contamination presents a significant set of problems to those attempting to remediate the soil. Bioremediation has received considerable attention, as a potential answer to the obvious remediation needs. Composting technology represents a promising means to use indigen...
NASA Technical Reports Server (NTRS)
Bowin, C. O.
1976-01-01
Lunar gravitational properties were analyzed along with the development of flat moon and curved moon computer models. Gravity anomalies and mascons were given particular attention. Geophysical and geological considerations were included, and comparisons were made between the gravitional fields of the Earth, Mars, and the Moon.
THE SIGNIFICANCE OF ENTERIC VIRUSES AND WATERBORNE ILLNESS
With growing concern over drinking water safety, considerable attention has been directed towards microbial pathogens in source waters, and the adequacy of current methods used to detect, monitor and treat for these pathogens. The focus has been on bacterial and protozoan pathog...
Although surfactants have received considerable attention as a potential means for enhancing the recovery of organic compounds from the subsurface, only limited information is available regarding the micellar solubilization of common groundwater contaminants by nonionic surfactan...
Comprehensive Assessment of Children and Youth with ADHD.
ERIC Educational Resources Information Center
Burcham, Barbara G.; DeMers, Stephen T.
1995-01-01
Principles of comprehensive assessment of students with attention deficit hyperactivity disorder are examined in relation to legal compliance, special considerations for cultural diversity, medical diagnosis versus educational identification, and the problem-solving assessment model. Strengths and weakness of specific strategies are identified as…
Renewable energy sources and the realities of setting an energy agenda.
Potocnik, Janez
2007-02-09
The European Commission has been devoting considerable attention to energy issues. This Perspective describes recent progress in Europe toward achieving goals for renewable energy use, and the role that technology can play, as well as the new Strategic Energy Package.
The Role of Pictures in Learning Biology: Part 1, Perception and Observation.
ERIC Educational Resources Information Center
Reid, David
1990-01-01
The concept of a "picture superiority effect" is discussed. Examined are a number of perceptual considerations that need to be given to picture construction. Parameters which appear to attract the learner's attention to a picture are considered. (CW)
Responses of yeast biocontrol agents to environmental stress
USDA-ARS?s Scientific Manuscript database
Biological control of postharvest diseases, utilizing wild species and strains of antagonistic yeasts, is a research topic that has received considerable attention in the literature over the past 30 years. In principle, it represents a promising alternative to chemical fungicides for the management...
Effects of saltcedar invasion and biological control on small mammals
USDA-ARS?s Scientific Manuscript database
Effects of invasive saltcedars (Tamarix spp.) on bird populations and communities have received considerable interest, but impacts on other vertebrate taxa have received less attention. Moreover, only one published study examined effects on vertebrates of biological control efforts directed at saltc...
ESTROGENIC ACTIVITY OF OCTYLPHENOL, NONYLPHENOL, BISPHENOL A AND METHOXYCHLOR IN RATS
Considerable attention has recently been focused on environmental chemicals that disrupt the reproductive system by altering steroid receptor function. Although numerous in vitro and in vivo methods have been shown to be useful approaches for identifying chemicals that can disrup...
International Security Institutions, Domestic Politics, and Institutional Legitimacy
ERIC Educational Resources Information Center
Chapman, Terrence L.
2007-01-01
Scholars have devoted considerable attention to the informational role of international institutions. However, several questions about the informational aspects of institutional behavior remain underexplored: What determines how audiences respond to institutional decisions? Through what channels does information provision affect foreign policy? To…
Attentional bias towards and away from fearful faces is modulated by developmental amygdala damage.
Pishnamazi, Morteza; Tafakhori, Abbas; Loloee, Sogol; Modabbernia, Amirhossein; Aghamollaii, Vajiheh; Bahrami, Bahador; Winston, Joel S
2016-08-01
The amygdala is believed to play a major role in orienting attention towards threat-related stimuli. However, behavioral studies on amygdala-damaged patients have given inconsistent results-variously reporting decreased, persisted, and increased attention towards threat. Here we aimed to characterize the impact of developmental amygdala damage on emotion perception and the nature and time-course of spatial attentional bias towards fearful faces. We investigated SF, a 14-year-old with selective bilateral amygdala damage due to Urbach-Wiethe disease (UWD), and ten healthy controls. Participants completed a fear sensitivity questionnaire, facial expression classification task, and dot-probe task with fearful or neutral faces for spatial cueing. Three cue durations were used to assess the time-course of attentional bias. SF expressed significantly lower fear sensitivity, and showed a selective impairment in classifying fearful facial expressions. Despite this impairment in fear recognition, very brief (100 msec) fearful cues could orient SF's spatial attention. In healthy controls, the attentional bias emerged later and persisted longer. SF's attentional bias was due solely to facilitated engagement to fear, while controls showed the typical phenomenon of difficulty in disengaging from fear. Our study is the first to demonstrate the separable effects of amygdala damage on engagement and disengagement of spatial attention. The findings indicate that multiple mechanisms contribute in biasing attention towards fear, which vary in their timing and dependence on amygdala integrity. It seems that the amygdala is not essential for rapid attention to emotion, but probably has a role in assessment of biological relevance. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
1977-01-01
principles apply; however, special attention has to be given early in ana- ivsis to the number and kinds of discriminations required of the human observer...demands, to store, or to output desired information. Typically, these are not insurmountable problems, but they have to receive their due attention ... attention to calibration, data identification, noise, drift, and measureuent start/stop logic. Manual systems require special attention to the reliability of
Jitendra, Asha K; Dupaul, George J; Someki, Fumio; Tresco, Katy E
2008-01-01
Although children with Attention-Deficit Hyperactivity Disorder (ADHD) exhibit significant academic difficulties in school settings, considerably less attention is devoted to remediating their academic problems when compared to behavioral and social difficulties. The purpose of this article is to review empirically supported academic interventions for children with ADHD. Specific evidence-based academic interventions are described under the categories of reading and mathematics, with examples that illustrate teacher-mediated interventions focusing on basic skills (e.g., phonological awareness in reading, mathematics computation) and higher-level cognitive skills (e.g., collaborative strategic reading, CSR; schema-based instruction, SBI). Finally, implications for educational practice and directions for future research on school-based academic interventions for students with ADHD are discussed.
Analysis and control of employee turnover.
McConnell, Charles R
2007-01-01
Turnover is a relatively simple and easily described concept. However, considerable confusion often results when addressing turnover because of differences in how it is defined; that is, what is counted, how it is counted, and how the turnover rates are expressed. Turnover is also costly, although not enough attention is paid to its cost because so much of it is indirect, and thus, not readily visible. There are a variety of causes of turnover, some which can be corrected and some which cannot be avoided. Reducing or otherwise controlling turnover requires continuing management attention to its causes and constant recognition of what can and should be controlled and what cannot be controlled. Ongoing attention to turnover is an essential part of the department manager's role.
Measuring the effect of attention on simple visual search.
Palmer, J; Ames, C T; Lindsey, D T
1993-02-01
Set-size in visual search may be due to 1 or more of 3 factors: sensory processes such as lateral masking between stimuli, attentional processes limiting the perception of individual stimuli, or attentional processes affecting the decision rules for combining information from multiple stimuli. These possibilities were evaluated in tasks such as searching for a longer line among shorter lines. To evaluate sensory contributions, display set-size effects were compared with cuing conditions that held sensory phenomena constant. Similar effects for the display and cue manipulations suggested that sensory processes contributed little under the conditions of this experiment. To evaluate the contribution of decision processes, the set-size effects were modeled with signal detection theory. In these models, a decision effect alone was sufficient to predict the set-size effects without any attentional limitation due to perception.
Shen, Christina; Popescu, Florin C; Hahn, Eric; Ta, Tam T M; Dettling, Michael; Neuhaus, Andres H
2014-07-01
Attention deficits, among other cognitive deficits, are frequently observed in schizophrenia. Although valid and reliable neurocognitive tasks have been established to assess attention deficits in schizophrenia, the hierarchical value of those tests as diagnostic discriminants on a single-subject level remains unclear. Thus, much research is devoted to attention deficits that are unlikely to be translated into clinical practice. On the other hand, a clear hierarchy of attention deficits in schizophrenia could considerably aid diagnostic decisions and may prove beneficial for longitudinal monitoring of therapeutic advances. To propose a diagnostic hierarchy of attention deficits in schizophrenia, we investigated several facets of attention in 86 schizophrenia patients and 86 healthy controls using a set of established attention tests. We applied state-of-the-art machine learning algorithms to determine attentive test variables that enable an automated differentiation between schizophrenia patients and healthy controls. After feature preranking, hypothesis building, and hypothesis validation, the polynomial support vector machine classifier achieved a classification accuracy of 90.70% ± 2.9% using psychomotor speed and 3 different attention parameters derived from sustained and divided attention tasks. Our study proposes, to the best of our knowledge, the first hierarchy of attention deficits in schizophrenia by identifying the most discriminative attention parameters among a variety of attention deficits found in schizophrenia patients. Our results offer a starting point for hierarchy building of schizophrenia-associated attention deficits and contribute to translating these concepts into diagnostic and therapeutic practice on a single-subject level. © The Author 2013. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.
Fosco, Whitney D; Hawk, Larry W
2017-02-01
A child's ability to sustain attention over time (AOT) is critical in attention-deficit/hyperactivity disorder (ADHD), yet no prior work has examined the extent to which a child's decrement in AOT on laboratory tasks relates to clinically-relevant behavior. The goal of this study is to provide initial evidence for the criterion validity of laboratory assessments of AOT. A total of 20 children with ADHD (7-12 years of age) who were enrolled in a summer treatment program completed two lab attention tasks (a continuous performance task and a self-paced choice discrimination task) and math seatwork. Analyses focused on relations between attention task parameters and math productivity. Individual differences in overall attention (OA) measures (averaged across time) accounted for 23% of the variance in math productivity, supporting the criterion validity of lab measures of attention. The criterion validity was enhanced by consideration of changes in AOT. Performance on all laboratory attention measures deteriorated as time-on-task increased, and individual differences in the decrement in AOT accounted for 40% of the variance in math productivity. The only variable to uniquely predict math productivity was from the self-paced choice discrimination task. This study suggests that attention tasks in the lab do predict a clinically-relevant target behavior in children with ADHD, supporting their use as a means to study attention processes in a controlled environment. Furthermore, this prediction is improved when attention is examined as a function of time-on-task and when the attentional demands are consistent between lab and life contexts.
Moss, Simon A; Wilson, Samuel G; Irons, Melanie; Naivalu, Carmen
2017-12-01
Some research shows that people who often contemplate their future tend to be healthier. Yet the burgeoning literature on mindfulness demonstrates that people who are more attuned to their immediate experiences also enjoy many benefits. To reconcile these principles, many scholars recommend that people should distribute their attention, somewhat evenly, across the past, present, and future-but have not clarified how people should achieve this goal. We test the possibility that people who perceive their future as vivid and certain, called future clarity, might be able to both orient their attention to the future as well as experience mindfulness. Specifically, future clarity could diminish the inclination of people to reach decisions prematurely and dismiss information that contradicts these decisions, called need for closure-tendencies that diminish consideration of future consequences and mindfulness, respectively. In this cross-sectional study, 194 participants completed measures of mindfulness, consideration of future consequences, need for closure, and future clarity. Consistent with hypotheses, future clarity was positively associated with both mindfulness and consideration of future consequences. Need for closure partly mediated these relationships. Accordingly, interventions that empower people to shape and to clarify their future might generate the benefits of both mindfulness and a future orientation. Copyright © 2017 John Wiley & Sons, Ltd.
Mathematics for Life: Sustainable Mathematics Education
ERIC Educational Resources Information Center
Renert, Moshe
2011-01-01
Ecological sustainability has not been a major focus of mathematics education research, even though it has attracted considerable attention in other areas of educational research in the past decade. The connections between mathematics education and ecological sustainability are not readily apparent. This paper explores how mathematics educators…
Depression and Distortion in the Attribution of Causality
ERIC Educational Resources Information Center
Rizley, Ross
1978-01-01
Two cognitive models of depression have attracted considerable attention recently: Seligman's (1975) learned helplessness model and Beck's (1967) cognitive schema approach. Describes each model and, in two studies, evaluates the assumption that depression is associated with systematic distortion in cognition regarding causal and controlling…
School-Based Extracurricular Astronomy
ERIC Educational Resources Information Center
Stanger, Jeffrey J.
2010-01-01
The International Year of Astronomy in 2009 focused considerable public attention on Astronomy and generated valuable resources for educators. These activities are an effective vehicle for promoting Science to students and to the wider school community. The most engaging practical astronomy activities are best delivered with sustained support from…
Annotated Bibliography of Relative Sea Level Change
1991-09-01
Millennial Basis, Morner and Kui-len, eds., D. Reidel. Publishing Company, pp 571-604. Over the last few years, considerable attention has been given to...historic erosion rates. Curiously , the ability to model statistically the historic shore erosion rate is best on those reaches already substantially
[The 14/2006 law on human assisted reproduction techniques: scientific and ethical considerations].
Lacadena, Juan-Ramón
2006-01-01
The new Spanish Law on Artificial Human Reproduction Techniques is analyzed from the scientific, ethical and legal points of view, paying special attention to the preimplantational diagnosis and the experimental utilization of gametes and preembryos. Other items are also analyzed.
Copyright, the Internet, and Other Legal Issues.
ERIC Educational Resources Information Center
Gasaway, Laura N.
1998-01-01
Copyright and other intellectual property issues have dominated discussions of legal issues surrounding the Internet. There are other issues of considerable importance that also attract attention. Five legal issues affecting the Internet are addressed: copyright, online service-provider liability, database protection, obscenity, and privacy. Cited…
An Arena of Comfort during Adolescence.
ERIC Educational Resources Information Center
Buri, John R.; And Others
Research has consistently shown parents' nurturance, acceptance, affection, support, and attention to be positively related to their children's self-esteem. Absent in these investigations of the relationship between parental nurturance and self-esteem, however, has been a consideration of whether the nurturance bases upon which these…
ERIC Educational Resources Information Center
Troy, Thomas D.; Schwaab, Karl E.
1981-01-01
Legal aspects of field trips are addressed, with special attention on planning and implementation aspects which warrant legal consideration. Suggestions are based on information obtained from studies which reviewed and analyzed court cases, with recommendations geared to lessen the likelihood that negligence suits will result if students sustain…
Parameters of Institutional Change: Chicano Experience in Education.
ERIC Educational Resources Information Center
Santana, Ray; And Others
During the 1960's, the Chicano movement directed considerable attention, energy, and resources toward educational change. The predominant mood was optimism and anticipation of major institutional change; the predominant tactic used was militant confrontation. Countless confrontations occurred and numerous plans and strategies for educational…
Extrasensory Perception Research: Difficulties and Implications for Education.
ERIC Educational Resources Information Center
McAdams, Elizabeth E.
In recent years, gradually increased acceptance and heightened attention have been granted to extrasensory perception (ESP) research as a legitimate branch of scientific inquiry. This research holds significant implications for education despite difficulties involved with its consideration. Extrasensory perception, an organism's apparent access to…
Quality control/quality assurance testing for joint density and segregation of asphalt mixtures.
DOT National Transportation Integrated Search
2013-04-01
Longitudinal joint quality control/assurance is essential to the successful performance of asphalt pavements and it has received considerable amount of attention in recent years. The purpose of the study is to evaluate the level of compaction at the ...
Political Simulations Using Excel
ERIC Educational Resources Information Center
Jackson, Steven F.
2013-01-01
Simulations have received considerable attention as a tool to promote problem-solving skills, intense involvement, and high-order thinking among students. Whether semester-long exercises or a single-class session, simulations are often used in areas of conflict studies, diplomatic studies, trade disputes, electoral processes, and policy and legal…
Designing Instructional Materials: Some Guidelines.
ERIC Educational Resources Information Center
Burbank, Lucille; Pett, Dennis
Guidelines for the design of instructional materials are outlined in this paper. The principles of design are presented in five major categories: (1) general design (structural appeal and personal appeal); (2) instructional design (attention, memory, concept learning, and attitude change); (3) visual design (media considerations, pictures, graphs…
Analytical Sociology: A Bungean Appreciation
ERIC Educational Resources Information Center
Wan, Poe Yu-ze
2012-01-01
Analytical sociology, an intellectual project that has garnered considerable attention across a variety of disciplines in recent years, aims to explain complex social processes by dissecting them, accentuating their most important constituent parts, and constructing appropriate models to understand the emergence of what is observed. To achieve…
Heat shock improves stress tolerance and biocontrol performance of Rhodotorula mucilaginosa
USDA-ARS?s Scientific Manuscript database
Biological control of postharvest diseases, utilizing wild species and strains of antagonistic yeasts, is a research topic and eco-friendly management approach that has received considerable attention. A few yeast-based biocontrol products are available in the market. Ecological fitness, stress to...
Knowledge-Based Entrepreneurship in a Boundless Research System
ERIC Educational Resources Information Center
Dell'Anno, Davide
2008-01-01
International entrepreneurship and knowledge-based entrepreneurship have recently generated considerable academic and non-academic attention. This paper explores the "new" field of knowledge-based entrepreneurship in a boundless research system. Cultural barriers to the development of business opportunities by researchers persist in some academic…
Probability from a Socio-Cultural Perspective
ERIC Educational Resources Information Center
Sharma, Sashi
2016-01-01
There exists considerable and rich literature on students' misconceptions about probability; less attention has been paid to the development of students' probabilistic thinking in the classroom. Grounded in an analysis of the literature, this article offers a lesson sequence for developing students' probabilistic understanding. In particular, a…
Reconsidering Formative Measurement
ERIC Educational Resources Information Center
Howell, Roy D.; Breivik, Einar; Wilcox, James B.
2007-01-01
The relationship between observable responses and the latent constructs they are purported to measure has received considerable attention recently, with particular focus on what has become known as formative measurement. This alternative to reflective measurement in the area of theory-testing research is examined in the context of the potential…
International Large-Scale Assessments: What Uses, What Consequences?
ERIC Educational Resources Information Center
Johansson, Stefan
2016-01-01
Background: International large-scale assessments (ILSAs) are a much-debated phenomenon in education. Increasingly, their outcomes attract considerable media attention and influence educational policies in many jurisdictions worldwide. The relevance, uses and consequences of these assessments are often the focus of research scrutiny. Whilst some…
Carbaryl neurotoxicity across the life-span of the Brown-Norway rat
Demographics show that the proportion of older adults is increasing every year. While there has been considerable attention paid to potential sensitivity of the young to environmental chemicals, there is much less known about the relative vulnerability of the aged. Differences in...
A Clinical Study of Phenomenology and Comorbidity of Paediatric Bipolar Disorder
ERIC Educational Resources Information Center
Gupta, Pavan Kumar; T., Sivakumar; Agarwal, Vivek; Sitholey, Prabhat
2012-01-01
Background: Considerable controversy exists regarding clinical presentation, diagnosis, and comorbidities especially with Attention Deficit Hyperactivity Disorder (ADHD), in paediatric Bipolar Disorder (BPD). Aims and objectives: To describe phenomenology and comorbidities of paediatric BPD. Method: 78 Subjects (6-16 years) attending child and…
ERIC Educational Resources Information Center
Fields, Cheryl
2005-01-01
Another topic involving privacy has attracted considerable attention in recent months--the "student unit record" issue. The U.S. Department of Education concluded in March that it would be feasible to help address lawmakers' concerns about accountability in higher education by constructing a database capable of tracking students from institution…
Murphy, Susan L
2009-02-01
Accelerometers are being increasingly used in studies of physical activity (PA) among older adults, however the use of these monitors requires some specialized knowledge and up-to-date information on technological innovations. The purpose of this review article is to provide researchers with a guide to some commonly-used accelerometers in order to better design and conduct PA research with older adults. A literature search was conducted to obtain all available literature on commonly-used accelerometers in older adult samples with specific attention to articles discussing research design. The use of accelerometers in older adults requires a basic understanding of the type being used, rationale for their placement, and attention to calibration when needed. The updated technology in some monitors should make study conduct less difficult, however comparison studies of the newer versus the older generation models will be needed. Careful considerations for design and conduct of accelerometer research as outlined in this review should help to enhance the quality and comparability of future research studies.
Diabetes as a model for the disparate public response to acute versus chronic diseases.
Bergman, Michael; Lonier, Jacqueline; Fink, Dorothy
2016-03-01
The public health outcry toward infectious entities appears to dwarf chronic diseases such as diabetes. This disparity is particularly astonishing given the considerable prevalence of diabetes and prediabetes. Diseases associated with short-term morbidity and mortality therefore seem to garner attention and demand an immediate public health response, whereas chronic illnesses, which can be considerably more devastating in the longer term, receive relatively less notoriety. It should not, however, be misconstrued that one disease entity is more important than the other--it is critical that both acute and chronic entities are given balanced attention in the public health, governmental, and scientific realms. The current perspective reflects on the disparate public health purviews toward acute and chronic illnesses, describes why prevention is so difficult and challenging, and addresses what can be done to reverse this trend. If there is any hope of conquering the spiraling prediabetes and diabetes epidemics, the medical community must grapple with the complex issues herein raised.
Martinez, Katherine; McDonald, Courtney
2017-11-01
Familial violence poses a serious public health concern and has therefore received a considerable amount of attention from academics and practitioners alike. Research within this field has found that parent-to-parent and parent-to-child violence often occur simultaneously and are especially prevalent within households that suffer from social and environmental stressors. Sibling violence and its relationship to these other forms of familial violence has received considerably less attention, largely related to the widely held belief that sibling violence is natural, especially for boys. Using the Scale of Negative Family Interactions (SNFI), parent-to-child and sibling-to-sibling violence is investigated. Specifically, the relationship between participants' gender and sexual identities and their reports of familial violence are explored to better understand participants' gendered and sexed experiences. Data suggest that gender and sexual minorities may have a unique experience of familial violence, although further research is needed in this area.
Speciation reversal and biodiversity dynamics with hybridization in changing environments.
Seehausen, Ole; Takimoto, Gaku; Roy, Denis; Jokela, Jukka
2008-01-01
A considerable fraction of the world's biodiversity is of recent evolutionary origin and has evolved as a by-product of, and is maintained by, divergent adaptation in heterogeneous environments. Conservationists have paid attention to genetic homogenization caused by human-induced translocations (e.g. biological invasions and stocking), and to the importance of environmental heterogeneity for the ecological coexistence of species. However, far less attention has been paid to the consequences of loss of environmental heterogeneity to the genetic coexistence of sympatric species. Our review of empirical observations and our theoretical considerations on the causes and consequences of interspecific hybridization suggest that a loss of environmental heterogeneity causes a loss of biodiversity through increased genetic admixture, effectively reversing speciation. Loss of heterogeneity relaxes divergent selection and removes ecological barriers to gene flow between divergently adapted species, promoting interspecific introgressive hybridization. Since heterogeneity of natural environments is rapidly deteriorating in most biomes, the evolutionary ecology of speciation reversal ought to be fully integrated into conservation biology.
Lu, Zhong-Lin
2009-01-01
Sensory physiologists and psychologists have recognized the importance of attention on human performance for more than 100 years. Since the 1970s, controlled and extensive experiments have examined effects of selective attention to a location in space or to an object. In addition to behavioral studies, cognitive neuroscientists have investigated the neural bases of attention. In this paper, I briefly review some classical attention paradigms, recent advances on the theory of attention, and some new insights from psychophysics and cognitive neuroscience. The focus is on the mechanisms of attention, that is, how attention improves human performance. Situations in which the perception of objects is unchanged, but performance may differ due to different decision structures, are distinguished from those in which attention changes the perceptual processes. The perceptual template model is introduced as a theoretical framework for analyzing mechanisms of attention. I also present empirical evidence for two attention mechanisms, stimulus enhancement and external noise exclusion, from psychophysics, neurophysiology and brain imaging. PMID:20523762
Amplified Arctic warming by phytoplankton under greenhouse warming.
Park, Jong-Yeon; Kug, Jong-Seong; Bader, Jürgen; Rolph, Rebecca; Kwon, Minho
2015-05-12
Phytoplankton have attracted increasing attention in climate science due to their impacts on climate systems. A new generation of climate models can now provide estimates of future climate change, considering the biological feedbacks through the development of the coupled physical-ecosystem model. Here we present the geophysical impact of phytoplankton, which is often overlooked in future climate projections. A suite of future warming experiments using a fully coupled ocean-atmosphere model that interacts with a marine ecosystem model reveals that the future phytoplankton change influenced by greenhouse warming can amplify Arctic surface warming considerably. The warming-induced sea ice melting and the corresponding increase in shortwave radiation penetrating into the ocean both result in a longer phytoplankton growing season in the Arctic. In turn, the increase in Arctic phytoplankton warms the ocean surface layer through direct biological heating, triggering additional positive feedbacks in the Arctic, and consequently intensifying the Arctic warming further. Our results establish the presence of marine phytoplankton as an important potential driver of the future Arctic climate changes.
DOE Office of Scientific and Technical Information (OSTI.GOV)
He, Tingchao; Tian, Xiaoqing; Lin, Xiaodong, E-mail: linxd@szu.edu.cn, E-mail: hdsun@ntu.edu.sg
Light-emitting nonlinear optical molecules, especially those with large Stokes shifts and broad tunability of their emission wavelength, have attracted considerable attention for various applications including biomedical imaging and fluorescent sensors. However, most fluorescent chromophores have only limited potential for such applications due to small Stokes shifts, narrow tunability of fluorescence emissions, and small optical nonlinearity in highly polar solvents. In this work, we demonstrate that a two-photon absorbing stilbene chromophore exhibits a large two-photon absorption action cross-section (ηδ = 320 GM) in dimethylsulfoxide (DMSO) and shows broad fluorescence tunability (125 nm) by manipulating the polarity of the surrounding medium. Importantly, a very large Stokesmore » shift of up to 227 nm is achieved in DMSO. Thanks to these features, this chromophore can be utilized as a two-photon probe for bioimaging applications and in an ultrasensitive solid-state gas detector.« less
Critical review: Uncharted waters? The future of the electricity-water nexus.
Sanders, Kelly T
2015-01-06
Electricity generation often requires large amounts of water, most notably for cooling thermoelectric power generators and moving hydroelectric turbines. This so-called "electricity-water nexus" has received increasing attention in recent years by governments, nongovernmental organizations, industry, and academics, especially in light of increasing water stress in many regions around the world. Although many analyses have attempted to project the future water requirements of electricity generation, projections vary considerably due to differences in temporal and spatial boundaries, modeling frameworks, and scenario definitions. This manuscript is intended to provide a critical review of recent publications that address the future water requirements of electricity production and define the factors that will moderate the water requirements of the electric grid moving forward to inform future research. The five variables identified include changes in (1) fuel consumption patterns, (2) cooling technology preferences, (3) environmental regulations, (4) ambient climate conditions, and (5) electric grid characteristics. These five factors are analyzed to provide guidance for future research related to the electricity-water nexus.
Electrochemical DNA biosensor based on the BDD nanograss array electrode.
Jin, Huali; Wei, Min; Wang, Jinshui
2013-04-10
The development of DNA biosensor has attracted considerable attention due to their potential applications, including gene analysis, clinical diagnostics, forensic study and more medical applications. Using electroactive daunomycin as an indicator, the hybridization detection was measured by differential pulse voltammetry in this study. Electrochemical DNA biosensor was developed based on the BDD film electrode (fBDD) and BDD nanograss array electrode (nBDD). In comparison with fBDD and AuNPs/CA/fBDD electrode, the lower semicircle diameter of electrochemical impedance spectroscopy obtained on nBDD and AuNPs/CA/nBDD electrode indicated that the presence of nanograss array improved the reactive site, reduced the interfacial resistance, and made the electron transfer easier. Using electroactive daunomycin as an indicator, the hybridization detection was measured by differential pulse voltammetry. The experimental results demonstrated that the prepared AuNPs/CA/nBDD electrode was suitable for DNA hybridization with favorable performance of faster response, higher sensitivity, lower detection limit and satisfactory selectivity, reproducibility and stability.
Electrochemical DNA biosensor based on the BDD nanograss array electrode
2013-01-01
Background The development of DNA biosensor has attracted considerable attention due to their potential applications, including gene analysis, clinical diagnostics, forensic study and more medical applications. Using electroactive daunomycin as an indicator, the hybridization detection was measured by differential pulse voltammetry in this study. Results Electrochemical DNA biosensor was developed based on the BDD film electrode (fBDD) and BDD nanograss array electrode (nBDD). In comparison with fBDD and AuNPs/CA/fBDD electrode, the lower semicircle diameter of electrochemical impedance spectroscopy obtained on nBDD and AuNPs/CA/nBDD electrode indicated that the presence of nanograss array improved the reactive site, reduced the interfacial resistance, and made the electron transfer easier. Using electroactive daunomycin as an indicator, the hybridization detection was measured by differential pulse voltammetry. Conclusions The experimental results demonstrated that the prepared AuNPs/CA/nBDD electrode was suitable for DNA hybridization with favorable performance of faster response, higher sensitivity, lower detection limit and satisfactory selectivity, reproducibility and stability. PMID:23575250
Lee, Seunghwa; Kim, Dahee; Lee, Jaeyoung
2015-12-01
Electrocatalytic conversion of carbon dioxide (CO2) has recently received considerable attention as one of the most feasible CO2 utilization techniques. In particular, copper and copper-derived catalysts have exhibited the ability to produce a number of organic molecules from CO2. Herein, we report a chloride (Cl)-induced bi-phasic cuprous oxide (Cu2O) and metallic copper (Cu) electrode (Cu2OCl) as an efficient catalyst for the formation of high-carbon organic molecules by CO2 conversion, and identify the origin of electroselectivity toward the formation of high-carbon organic compounds. The Cu2OCl electrocatalyst results in the preferential formation of multi-carbon fuels, including n-propanol and n-butane C3-C4 compounds. We propose that the remarkable electrocatalytic conversion behavior is due to the favorable affinity between the reaction intermediates and the catalytic surface. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Synthesis of Aluminium Nanoparticles in A Water/Polyethylene Glycol Mixed Solvent using μ-EDM
NASA Astrophysics Data System (ADS)
Sahu, R. K.; Hiremath, Somashekhar S.
2017-08-01
Nanoparticles present a practical way of retaining the results of the property at the atomic or molecular level. Due to the recent use of nanoparticles in scientific, industrial and medical applications, synthesis of nanoparticles and their characterization have become considerably important. Currently, aluminium nanoparticles have attracted significant research attention because of their reasonable cost, unique properties and interdisciplinary emerging applications. The present paper reports the synthesis of aluminium nanoparticles in the mixture of Deionized water (DI water) and Polyethylene Glycol (PEG) using a developed micro-Electrical Discharge Machining (μ-EDM) method. PEG was used as a stabilizer to prevent nanoparticles from agglomeration produced during the μ -EDM process. The synthesized aluminium nanoparticles were examined by Transmission Electron Microscopy (TEM), Energy Dispersive Analysis by X-rays (EDAX) and Selected Area Electron Diffraction (SAED) pattern to determine their size, shape, chemical nature and crystal structure. The average size of the polyhedral aluminium nanoparticles is found to be 196 nm.
Noise squeezing of fields that bichromatically excite atoms in a cavity.
Li, Lingchao; Hu, Xiangming; Rao, Shi; Xu, Jun
2016-11-14
It is well known that bichromatic excitation on one common transition can tune the emission or absorption spectra of atoms due to the modulation frequency dependent non-linearities. However little attention has been focused on the quantum dynamics of fields under bichromatic excitation. Here we present dissipative effects on noise correlations of fields in bichromatic interactions with atoms in cavities. We first consider an ensemble of two-level atoms that interacts with the two cavity fields of different frequencies and considerable amplitudes. By transferring the atom-field nonlinearities to the dressed atoms we separate out the dissipative interactions of Bogoliubov modes with the dressed atoms. The Bogoliubov mode dissipation establishes stable two-photon processes of two involved fields and therefore leads to two-mode squeezing. As a generalization, we then consider an ensemble of three-level Λ atoms for cascade bichromatic interactions. We extract the Bogoliubov-like four-mode interactions, which establish a quadrilateral of the two-photon processes of four involved fields and thus result in four-mode squeezing.
Uniformity of LED light illumination in application to direct imaging lithography
NASA Astrophysics Data System (ADS)
Huang, Ting-Ming; Chang, Shenq-Tsong; Tsay, Ho-Lin; Hsu, Ming-Ying; Chen, Fong-Zhi
2016-09-01
Direct imaging has widely applied in lithography for a long time because of its simplicity and easy-maintenance. Although this method has limitation of lithography resolution, it is still adopted in industries. Uniformity of UV irradiance for a designed area is an important requirement. While mercury lamps were used as the light source in the early stage, LEDs have drawn a lot of attention for consideration from several aspects. Although LED has better and better performance, arrays of LEDs are required to obtain desired irradiance because of limitation of brightness for a single LED. Several effects are considered that affect the uniformity of UV irradiance such as alignment of optics, temperature of each LED, performance of each LED due to production uniformity, and pointing of LED module. Effects of these factors are considered to study the uniformity of LED Light Illumination. Numerical analysis is performed by assuming a serious of control factors to have a better understanding of each factor.
Jiang, Guoying; Yu, Christopher; Yadav, Daniela B; Hu, Zhilan; Amurao, Annamarie; Duenas, Eileen; Wong, Marc; Iverson, Mark; Zheng, Kai; Lam, Xanthe; Chen, Jia; Vega, Roxanne; Ulufatu, Sheila; Leddy, Cecilia; Davis, Helen; Shen, Amy; Wong, Pin Y; Harris, Reed; Wang, Y John; Li, Dongwei
2016-07-01
Due to their potential influence on stability, pharmacokinetics, and product consistency, antibody charge variants have attracted considerable attention in the biotechnology industry. Subtle to significant differences in the level of charge variants and new charge variants under various cell culture conditions are often observed during routine manufacturing or process changes and pose a challenge when demonstrating product comparability. To explore potential solutions to control charge heterogeneity, monoclonal antibodies (mAbs) with native, wild-type C-termini, and mutants with C-terminal deletions of either lysine or lysine and glycine were constructed, expressed, purified, and characterized in vitro and in vivo. Analytical and physiological characterization demonstrated that the mAb mutants had greatly reduced levels of basic variants without decreasing antibody biologic activity, structural stability, pharmacokinetics, or subcutaneous bioavailability in rats. This study provides a possible solution to mitigate mAb heterogeneity in C-terminal processing, improve batch-to-batch consistency, and facilitate the comparability study during process changes. Published by Elsevier Inc.
In Vitro Modeling of Mechanics in Cancer Metastasis
2017-01-01
In addition to a multitude of genetic and biochemical alterations, abnormal morphological, structural, and mechanical changes in cells and their extracellular environment are key features of tumor invasion and metastasis. Furthermore, it is now evident that mechanical cues alongside biochemical signals contribute to critical steps of cancer initiation, progression, and spread. Despite its importance, it is very challenging to study mechanics of different steps of metastasis in the clinic or even in animal models. While considerable progress has been made in developing advanced in vitro models for studying genetic and biological aspects of cancer, less attention has been paid to models that can capture both biological and mechanical factors realistically. This is mainly due to lack of appropriate models and measurement tools. After introducing the central role of mechanics in cancer metastasis, we provide an outlook on the emergence of novel in vitro assays and their combination with advanced measurement technologies to probe and recapitulate mechanics in conditions more relevant to the metastatic disease. PMID:29457129
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bhaskaran-Nair, Kiran; Kowalski, Karol; Jarrell, Mark
2015-11-05
Polyacenes have attracted considerable attention due to their use in organic based optoelectronic materials. Polyacenes are polycyclic aromatic hydrocarbons composed of fused benzene rings. Key to understanding and design of new functional materials is an understanding of their excited state properties starting with their electron affinity (EA) and ionization potential (IP). We have developed a highly accurate and com- putationally e*fficient EA/IP equation of motion coupled cluster singles and doubles (EA/IP-EOMCCSD) method that is capable of treating large systems and large basis set. In this study we employ the EA/IP-EOMCCSD method to calculate the electron affinity and ionization potential ofmore » naphthalene, anthracene, tetracene, pentacene, hex- acene and heptacene. We have compared our results with other previous theoretical studies and experimental data. Our EA/IP results are in very good agreement with experiment and when compared with the other theoretical investigations our results represent the most accurate calculations as compared to experiment.« less
Regional groundwater flow modeling of the Geba basin, northern Ethiopia
NASA Astrophysics Data System (ADS)
Gebreyohannes, Tesfamichael; De Smedt, Florimond; Walraevens, Kristine; Gebresilassie, Solomon; Hussien, Abdelwassie; Hagos, Miruts; Amare, Kassa; Deckers, Jozef; Gebrehiwot, Kindeya
2017-05-01
The Geba basin is one of the most food-insecure areas of the Tigray regional state in northern Ethiopia due to recurrent drought resulting from erratic distribution of rainfall. Since the beginning of the 1990s, rain-fed agriculture has been supported through small-scale irrigation schemes mainly by surface-water harvesting, but success has been limited. Hence, use of groundwater for irrigation purposes has gained considerable attention. The main purpose of this study is to assess groundwater resources in the Geba basin by means of a MODFLOW modeling approach. The model is calibrated using observed groundwater levels, yielding a clear insight into the groundwater flow systems and reserves. Results show that none of the hydrogeological formations can be considered as aquifers that can be exploited for large-scale groundwater exploitation. However, aquitards can be identified that can support small-scale groundwater abstraction for irrigation needs in regions that are either designated as groundwater discharge areas or where groundwater levels are shallow and can be tapped by hand-dug wells or shallow boreholes.
Micro/Nanostructured Materials for Sodium Ion Batteries and Capacitors.
Li, Feng; Zhou, Zhen
2018-02-01
High-efficiency energy storage technologies and devices have received considerable attention due to their ever-increasing demand. Na-related energy storage systems, sodium ion batteries (SIBs) and sodium ion capacitors (SICs), are regarded as promising candidates for large-scale energy storage because of the abundant sources and low cost of sodium. In the last decade, many efforts, including structural and compositional optimization, effective modification of available materials, and design and exploration of new materials, have been made to promote the development of Na-related energy storage systems. In this Review, the latest developments of micro/nanostructured electrode materials for advanced SIBs and SICs, especially the rational design of unique composites with high thermodynamic stabilities and fast kinetics during charge/discharge, are summarized. In addition to the recent achievements, the remaining challenges with respect to fundamental investigations and commercialized applications are discussed in detail. Finally, the prospects of sodium-based energy storage systems are also described. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Lai, Q Q; Liu, M D; Gu, C C; Nie, H G; Xu, X J; Li, Z H; Yang, Z; Huang, S M
2016-02-21
Evaluating DNA methyltransferase (MTase) activity has received considerable attention due to its significance in the fields of early cancer clinical diagnostics and drug discovery. Herein, we proposed a novel label-free fluorescence method for MTase activity assay by coupling double-stranded DNA (dsDNA)-templated copper nanoparticles (CuNPs) with an endonuclease-assisted signal transduction system. In this strategy, dsDNA molecules were first methylated by DNA adenine methylation (Dam) MTase and then cleaved by the methylation-sensitive restriction endonuclease DpnI. The cleaved DNA fragments could not act as efficient templates for the formation of fluorescent CuNPs and thus no fluorescence signal was produced. Under optimized experimental conditions, the developed strategy exhibited a sensitive fluorescence response to Dam MTase activity. This strategy was also demonstrated to provide an excellent platform to the inhibitor screening for Dam MTase. These results demonstrated the great potential for the practical applications of the proposed strategy for Dam MTase activity assay.
The study on stage financing model of IT project investment.
Chen, Si-hua; Xu, Sheng-hua; Lee, Changhoon; Xiong, Neal N; He, Wei
2014-01-01
Stage financing is the basic operation of venture capital investment. In investment, usually venture capitalists use different strategies to obtain the maximum returns. Due to its advantages to reduce the information asymmetry and agency cost, stage financing is widely used by venture capitalists. Although considerable attentions are devoted to stage financing, very little is known about the risk aversion strategies of IT projects. This paper mainly addresses the problem of risk aversion of venture capital investment in IT projects. Based on the analysis of characteristics of venture capital investment of IT projects, this paper introduces a real option pricing model to measure the value brought by the stage financing strategy and design a risk aversion model for IT projects. Because real option pricing method regards investment activity as contingent decision, it helps to make judgment on the management flexibility of IT projects and then make a more reasonable evaluation about the IT programs. Lastly by being applied to a real case, it further illustrates the effectiveness and feasibility of the model.
The Study on Stage Financing Model of IT Project Investment
Xu, Sheng-hua; Xiong, Neal N.
2014-01-01
Stage financing is the basic operation of venture capital investment. In investment, usually venture capitalists use different strategies to obtain the maximum returns. Due to its advantages to reduce the information asymmetry and agency cost, stage financing is widely used by venture capitalists. Although considerable attentions are devoted to stage financing, very little is known about the risk aversion strategies of IT projects. This paper mainly addresses the problem of risk aversion of venture capital investment in IT projects. Based on the analysis of characteristics of venture capital investment of IT projects, this paper introduces a real option pricing model to measure the value brought by the stage financing strategy and design a risk aversion model for IT projects. Because real option pricing method regards investment activity as contingent decision, it helps to make judgment on the management flexibility of IT projects and then make a more reasonable evaluation about the IT programs. Lastly by being applied to a real case, it further illustrates the effectiveness and feasibility of the model. PMID:25147845
Gonzalo, Soledad; Llaneza, Veronica; Pulido-Reyes, Gerardo; Fernández-Piñas, Francisca; Bonzongo, Jean Claude; Leganes, Francisco; Rosal, Roberto; García-Calvo, Eloy; Rodea-Palomares, Ismael
2014-01-01
Aggregation raises attention in Nanotoxicology due to its methodological implications. Aggregation is a physical symptom of a more general physicochemical condition of colloidal particles, namely, colloidal stability. Colloidal stability is a global indicator of the tendency of a system to reduce its net surface energy, which may be achieved by homo-aggregation or hetero-aggregation, including location at bio-interfaces. However, the role of colloidal stability as a driver of ENM bioactivity has received little consideration thus far. In the present work, which focuses on the toxicity of nanoscaled Fe° nanoparticles (nZVI) towards a model microalga, we demonstrate that colloidal stability is a fundamental driver of ENM bioactivity, comprehensively accounting for otherwise inexplicable differential biological effects. The present work throws light on basic aspects of Nanotoxicology, and reveals a key factor which may reconcile contradictory results on the influence of aggregation in bioactivity of ENMs.
Thomas Young's contribution to visual optics: the Bakerian Lecture "on the mechanism of the eye".
Atchison, David A; Charman, W Neil
2010-10-15
Thomas Young (1773-1829) carried out major pioneering work in many different subjects. In 1800 he gave the Bakerian Lecture of the Royal Society on the topic of the "mechanism of the eye": this was published in the following year (T. Young, 1801). Young used his own design of optometer to measure refraction and accommodation, and discovered his own astigmatism. He considered the different possible origins of accommodation and confirmed that it was due to change in shape of the lens rather than to change in shape of the cornea or an increase in axial length. However, the paper also dealt with many other aspects of visual and ophthalmic optics, such as biometric parameters, peripheral refraction, longitudinal chromatic aberration, depth-of-focus and instrument myopia. These aspects of the paper have previously received little attention. We now give detailed consideration to these and other less-familiar features of Young's work and conclude that his studies remain relevant to many of the topics which currently engage visual scientists.
Cappello, A R; Dolce, V; Iacopetta, D; Martello, M; Fiorillo, M; Curcio, R; Muto, L; Dhanyalayam, D
2016-01-01
Elevated serum cholesterol, triglycerides and LDL levels are often associated with an increased incidence of atherosclerosis and coronary artery disease. The most effective therapeutic strategy against these diseases is based on statins administration, nevertheless some patients, especially those with metabolic syndrome fail to achieve their recommended LDL targets with statin therapy, moreover, it may induce many serious side effects. Several scientific studies have highlighted a strong correlation between diets rich in flavonoids and cardiovascular risk reduction. In particular, Citrus bergamia Risso, also known as bergamot, has shown a significant degree of hypocholesterolemic and antioxidant/radical scavenging activities. In addition, this fruit has attracted considerable attention due to its peculiar flavonoid composition, since it contains some flavanones that can act as natural statins. Hence, the study of bergamot flavonoids as metabolic regulators offers a great opportunity for screening and discovery of new therapeutic agents. Cholesterol metabolism, flavonoid composition and potential therapeutic use of C. bergamia Risso will be discussed in the following review.
Ho, Shih-Hsin; Zhu, Shishu; Chang, Jo-Shu
2017-12-01
Pollution of heavy metals (HMs) is a detrimental treat to human health and need to be cleaned up in a proper way. Biochar (BC), a low-cost and "green" adsorbent, has attracted significant attention due to its considerable HMs removal capacity. In particular, nano-metals have recently been used to assist BC in improving its reactivity, surface texture and magnetism. Synthesis methods and metal precursors greatly influence the properties and structures of the nanocomposites, thereby affecting their HMs removal performance. This review presents advances in synthesis methods, formation mechanisms and surface characteristics of BC nanocomposites, along with the discussions on HMs removal mechanisms and the effects of environmental factors on HMs removal efficiency. Performance of using BC nanocomposites to remediate real HMs-containing wastewater and issues associated with its process scale-up are also discussed. This review aims to provide useful information to facilitate the development of HMs removal by nanoscale-metal assisted BC. Copyright © 2017 Elsevier Ltd. All rights reserved.
Amplified Arctic warming by phytoplankton under greenhouse warming
Park, Jong-Yeon; Kug, Jong-Seong; Bader, Jürgen; Rolph, Rebecca; Kwon, Minho
2015-01-01
Phytoplankton have attracted increasing attention in climate science due to their impacts on climate systems. A new generation of climate models can now provide estimates of future climate change, considering the biological feedbacks through the development of the coupled physical–ecosystem model. Here we present the geophysical impact of phytoplankton, which is often overlooked in future climate projections. A suite of future warming experiments using a fully coupled ocean−atmosphere model that interacts with a marine ecosystem model reveals that the future phytoplankton change influenced by greenhouse warming can amplify Arctic surface warming considerably. The warming-induced sea ice melting and the corresponding increase in shortwave radiation penetrating into the ocean both result in a longer phytoplankton growing season in the Arctic. In turn, the increase in Arctic phytoplankton warms the ocean surface layer through direct biological heating, triggering additional positive feedbacks in the Arctic, and consequently intensifying the Arctic warming further. Our results establish the presence of marine phytoplankton as an important potential driver of the future Arctic climate changes. PMID:25902494
NASA Astrophysics Data System (ADS)
Shui, Y.; Liu, H. C.; Li, L. H.; Yu, G. G.; Liu, J.
2016-08-01
Research that assesses the scheduling ability of dams gamers a great deal of attention due to the global water resource crisis. These studies can provide useful and practical suggestions for scheduling the water resources of dams to solve problems, such as addressing ecological water needs and so on. Recent studies have primarily evaluated the schedule ability of dams according to their quantifiable attributes, such as water quantity, flow velocity, etc. However, the ecological and management status can directly determine the possibility and efficiency of a dam's water resource scheduling. This paper presents an evaluation model to assess the scheduling capacity of dams that takes into consideration ecological and management factors. In the experiment stage, this paper takes the Sha Ying river of the Huai He River Basin as an example to evaluate the scheduling ability of its dams. The results indicate that the proposed evaluation model can provide more precise and practical suggestions.
Nonlocal van der Waals functionals: The case of rare-gas dimers and solids
NASA Astrophysics Data System (ADS)
Tran, Fabien; Hutter, Jürg
2013-05-01
Recently, the nonlocal van der Waals (vdW) density functionals [M. Dion, H. Rydberg, E. Schröder, D. C. Langreth, and B. I. Lundqvist, Phys. Rev. Lett. 92, 246401 (2004), 10.1103/PhysRevLett.92.246401] have attracted considerable attention due to their good performance for systems where weak interactions are important. Since the physics of dispersion is included in these functionals, they are usually more accurate and show less erratic behavior than the semilocal and hybrid methods. In this work, several variants of the vdW functionals have been tested on rare-gas dimers (from He2 to Kr2) and solids (Ne, Ar, and Kr) and their accuracy compared to standard semilocal approximations, supplemented or not by an atom-pairwise dispersion correction [S. Grimme, J. Antony, S. Ehrlich, and H. Krieg, J. Chem. Phys. 132, 154104 (2010), 10.1063/1.3382344]. An analysis of the results in terms of energy decomposition is also provided.
The harm argument against surrogacy revisited: two versions not to forget.
Agnafors, Marcus
2014-08-01
It has been a common claim that surrogacy is morally problematic since it involves harm to the child or the surrogate-the harm argument. Due to a growing body of empirical research, the harm argument has seen a decrease in popularity, as there seems to be little evidence of harmful consequences of surrogacy. In this article, two revised versions of the harm argument are developed. It is argued that the two suggested versions of the harm argument survive the current criticism against the standard harm argument. The first version argues that the child is harmed by being separated from the gestational mother. The second version directs attention to the fact that surrogacy involves great incentives to keep the gestational mother's level of maternal-fetal attachment low, which tend to increase the risk of harm to the child. While neither of the two arguments is conclusive regarding the moral status of surrogacy, both constitute important considerations that are often ignored.
Ethical considerations in community oral health.
Naidoo, Sudeshni
2015-05-01
As the public's oral health care needs increase in complexity, there is renewed attention to the ethical dimensions of community oral health decision making and the development of public health ethics in teaching and research in dentistry. Despite their reduction globally, oral diseases persist with a particular distribution pattern that is a reflection of the increasingly widespread inequality in access to community oral health preventive and dental care. This is due to differences in the appropriateness, availability, accessibility, and acceptability of oral health education and the care provided. This article provides an overview of community oral health from an ethical perspective, including the importance of equity, human rights, and social justice in providing oral health care to the underserved. The need for a paradigm shift from highly technical and individualistic dental training curricula is discussed, together with the need to instill a holistic approach to ethical and social responsibility in new dental graduates. It concludes with some possible strategies, using the overarching principles of ethics and bioethics that are applicable to practice among vulnerable populations.