Sample records for considers returning excess

  1. 26 CFR 1.6050I-1 - Returns relating to cash in excess of $10,000 received in a trade or business.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... business use), but a $20,000 dump truck or a $20,000 factory machine is not. (3) Collectible. The term... of such person's passport, alien identification card, or other official document evidencing... driver's license or a credit card). In addition, a return will be considered incomplete if the person...

  2. 26 CFR 1.6050I-1 - Returns relating to cash in excess of $10,000 received in a trade or business.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... business use), but a $20,000 dump truck or a $20,000 factory machine is not. (3) Collectible. The term... of such person's passport, alien identification card, or other official document evidencing... driver's license or a credit card). In addition, a return will be considered incomplete if the person...

  3. 26 CFR 1.6050I-1 - Returns relating to cash in excess of $10,000 received in a trade or business.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... business use), but a $20,000 dump truck or a $20,000 factory machine is not. (3) Collectible. The term... of such person's passport, alien identification card, or other official document evidencing... driver's license or a credit card). In addition, a return will be considered incomplete if the person...

  4. 26 CFR 1.6050I-1 - Returns relating to cash in excess of $10,000 received in a trade or business.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... business use), but a $20,000 dump truck or a $20,000 factory machine is not. (3) Collectible. The term... of such person's passport, alien identification card, or other official document evidencing... driver's license or a credit card). In addition, a return will be considered incomplete if the person...

  5. 26 CFR 1.6050I-1 - Returns relating to cash in excess of $10,000 received in a trade or business.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... business use), but a $20,000 dump truck or a $20,000 factory machine is not. (3) Collectible. The term... of such person's passport, alien identification card, or other official document evidencing... driver's license or a credit card). In addition, a return will be considered incomplete if the person...

  6. Understanding the multifractality in portfolio excess returns

    NASA Astrophysics Data System (ADS)

    Chen, Cheng; Wang, Yudong

    2017-01-01

    The multifractality in stock returns have been investigated extensively. However, whether the autocorrelations in portfolio returns are multifractal have not been considered in the literature. In this paper, we detect multifractal behavior of returns of portfolios constructed based on two popular trading rules, size and book-to-market (BM) ratio. Using the multifractal detrended fluctuation analysis, we find that the portfolio returns are significantly multifractal and the multifractality is mainly attributed to long-range dependence. We also investigate the multifractal cross-correlation between portfolio return and market average return using the detrended cross-correlation analysis. Our results show that the cross-correlations of small fluctuations are persistent, while those of large fluctuations are anti-persistent.

  7. Insomnia, excessive sleepiness, excessive fatigue, anxiety, depression and shift work disorder in nurses having less than 11 hours in-between shifts.

    PubMed

    Eldevik, Maria Fagerbakke; Flo, Elisabeth; Moen, Bente Elisabeth; Pallesen, Ståle; Bjorvatn, Bjørn

    2013-01-01

    To assess if less than 11 hours off work between work shifts (quick returns) was related to insomnia, sleepiness, fatigue, anxiety, depression and shift work disorder among nurses. A questionnaire including established instruments measuring insomnia (Bergen Insomnia Scale), sleepiness (Epworth Sleepiness Scale), fatigue (Fatigue Questionnaire), anxiety/depression (Hospital Anxiety and Depression Scale) and shift work disorder was administered. Among the 1990 Norwegian nurses who participated in the study; 264 nurses had no quick returns, 724 had 1-30 quick returns and 892 had more than 30 quick returns during the past year. 110 nurses did not report the number of quick returns during the past year. The prevalence of insomnia, excessive sleepiness, excessive fatigue, anxiety, depression and shift work disorder was calculated within the three groups of nurses. Crude and adjusted logistic regression analyses were performed to assess the relation between quick returns and such complaints. We found a significant positive association between quick returns and insomnia, excessive sleepiness, excessive fatigue and shift work disorder. Anxiety and depression were not related to working quick returns. There is a health hazard associated with quick returns. Further research should aim to investigate if workplace strategies aimed at reducing the number of quick returns may reduce complaints among workers.

  8. 10 CFR Appendix I to Part 504 - Procedures for the Computation of the Real Cost of Capital

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... Government 13-week Treasury Bills, B=The “beta” coefficient—the relationship between the excess return on common stock and the excess return on the S&P 500 composite index, and R m=The mean excess return on the... statements of firms, and investment bankers. (2) The predicted nominal cost of debt (R d) may be estimated by...

  9. Investment Dynamics with Natural Expectations.

    PubMed

    Fuster, Andreas; Hebert, Benjamin; Laibson, David

    2010-01-01

    We study an investment model in which agents have the wrong beliefs about the dynamic properties of fundamentals. Specifically, we assume that agents underestimate the rate of mean reversion. The model exhibits the following six properties: (i) Beliefs are excessively optimistic in good times and excessively pessimistic in bad times. (ii) Asset prices are too volatile. (iii) Excess returns are negatively autocorrelated. (iv) High levels of corporate profits predict negative future excess returns. (v) Real economic activity is excessively volatile; the economy experiences amplified investment cycles. (vi) Corporate profits are positively autocorrelated in the short run and negatively autocorrelated in the medium run. The paper provides an illustrative model of animal spirits, amplified business cycles, and excess volatility.

  10. Investment Dynamics with Natural Expectations*

    PubMed Central

    Fuster, Andreas; Hebert, Benjamin; Laibson, David

    2012-01-01

    We study an investment model in which agents have the wrong beliefs about the dynamic properties of fundamentals. Specifically, we assume that agents underestimate the rate of mean reversion. The model exhibits the following six properties: (i) Beliefs are excessively optimistic in good times and excessively pessimistic in bad times. (ii) Asset prices are too volatile. (iii) Excess returns are negatively autocorrelated. (iv) High levels of corporate profits predict negative future excess returns. (v) Real economic activity is excessively volatile; the economy experiences amplified investment cycles. (vi) Corporate profits are positively autocorrelated in the short run and negatively autocorrelated in the medium run. The paper provides an illustrative model of animal spirits, amplified business cycles, and excess volatility. PMID:23243469

  11. Earnings Quality Measures and Excess Returns

    PubMed Central

    Perotti, Pietro; Wagenhofer, Alfred

    2014-01-01

    This paper examines how commonly used earnings quality measures fulfill a key objective of financial reporting, i.e., improving decision usefulness for investors. We propose a stock-price-based measure for assessing the quality of earnings quality measures. We predict that firms with higher earnings quality will be less mispriced than other firms. Mispricing is measured by the difference of the mean absolute excess returns of portfolios formed on high and low values of a measure. We examine persistence, predictability, two measures of smoothness, abnormal accruals, accruals quality, earnings response coefficient and value relevance. For a large sample of US non-financial firms over the period 1988–2007, we show that all measures except for smoothness are negatively associated with absolute excess returns, suggesting that smoothness is generally a favorable attribute of earnings. Accruals measures generate the largest spread in absolute excess returns, followed by smoothness and market-based measures. These results lend support to the widespread use of accruals measures as overall measures of earnings quality in the literature. PMID:26300582

  12. Earnings Quality Measures and Excess Returns.

    PubMed

    Perotti, Pietro; Wagenhofer, Alfred

    2014-06-01

    This paper examines how commonly used earnings quality measures fulfill a key objective of financial reporting, i.e., improving decision usefulness for investors. We propose a stock-price-based measure for assessing the quality of earnings quality measures. We predict that firms with higher earnings quality will be less mispriced than other firms. Mispricing is measured by the difference of the mean absolute excess returns of portfolios formed on high and low values of a measure. We examine persistence, predictability, two measures of smoothness, abnormal accruals, accruals quality, earnings response coefficient and value relevance. For a large sample of US non-financial firms over the period 1988-2007, we show that all measures except for smoothness are negatively associated with absolute excess returns, suggesting that smoothness is generally a favorable attribute of earnings. Accruals measures generate the largest spread in absolute excess returns, followed by smoothness and market-based measures. These results lend support to the widespread use of accruals measures as overall measures of earnings quality in the literature.

  13. On the Empirical Importance of the Conditional Skewness Assumption in Modelling the Relationship between Risk and Return

    NASA Astrophysics Data System (ADS)

    Pipień, M.

    2008-09-01

    We present the results of an application of Bayesian inference in testing the relation between risk and return on the financial instruments. On the basis of the Intertemporal Capital Asset Pricing Model, proposed by Merton we built a general sampling distribution suitable in analysing this relationship. The most important feature of our assumptions is that the skewness of the conditional distribution of returns is used as an alternative source of relation between risk and return. This general specification relates to Skewed Generalized Autoregressive Conditionally Heteroscedastic-in-Mean model. In order to make conditional distribution of financial returns skewed we considered the unified approach based on the inverse probability integral transformation. In particular, we applied hidden truncation mechanism, inverse scale factors, order statistics concept, Beta and Bernstein distribution transformations and also a constructive method. Based on the daily excess returns on the Warsaw Stock Exchange Index we checked the empirical importance of the conditional skewness assumption on the relation between risk and return on the Warsaw Stock Market. We present posterior probabilities of all competing specifications as well as the posterior analysis of the positive sign of the tested relationship.

  14. Determinants of the cost of capital for privately financed hospital projects in the UK.

    PubMed

    Colla, Paolo; Hellowell, Mark; Vecchi, Veronica; Gatti, Stefano

    2015-11-01

    Many governments make use of private finance contracts to deliver healthcare infrastructure. Previous work has shown that the rate of return to investors in these markets often exceeds the efficient level. Our focus is on the factors that influence that return. We examine the effect of macroeconomic, project- and firm-level variables using a detailed sample of 84 UK private finance initiative (PFI) contracts signed between 1997 and 2010. Of the above variables, macroeconomic conditions and lead sponsor size are related to the investor return. However, our results show a remarkable degree of stability in the return to investors over the 14-year period. We find evidence of a 'prevailing norm' that is robust to project- and firm-level variation. The sustainability of excess returns over a long period is indicative of a concentrated market structure. We argue that policymakers should consider new mechanisms for increasing competition in the equity market, while ensuring that authorities have the specialist resources required to negotiate efficient contract prices. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  15. New procedure speeds cold start, protects turbine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mallard, R.E.; Jordan, C.A.

    1995-09-01

    System dispatch from today`s power plants must consider availability of purchase power (buy and sell), fuel prices, and unit availability and efficiency. To gain the best combination of these factors, steam units must be capable of quick removal and return to service. However, unit startups are expensive, time consuming nd operationally demanding. For example, excessive thermal stresses can be catastrophic to a unit. With those factors in mind, Jacksonville Electric Authority (JEA) developed the ``valve open start`` procedure described here.

  16. Does the private sector receive an excessive return from investments in health care infrastructure projects? Evidence from the UK.

    PubMed

    Vecchi, Veronica; Hellowell, Mark; Gatti, Stefano

    2013-05-01

    This paper is concerned with the cost-efficiency of Private Finance Initiatives (PFIs) in the delivery of hospital facilities in the UK. We outline a methodology for identifying the "fair" return on equity, based on the Weighted Average Cost of Capital (WACC) of each investor. We apply this method to assess the expected returns on a sample of 77 contracts signed between 1997 and 2011 by health care provider organisations in the UK. We show that expected returns are in general in excess of the WACC benchmarks. The findings highlight significant problems in current procurement practices and the methodologies by which bids are assessed. To minimise the financial impact of hospital investments on health care systems, a regulatory regime must ensure that expected returns are set at the "fair" rate. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  17. Enhanced index tracking modelling in portfolio optimization

    NASA Astrophysics Data System (ADS)

    Lam, W. S.; Hj. Jaaman, Saiful Hafizah; Ismail, Hamizun bin

    2013-09-01

    Enhanced index tracking is a popular form of passive fund management in stock market. It is a dual-objective optimization problem, a trade-off between maximizing the mean return and minimizing the risk. Enhanced index tracking aims to generate excess return over the return achieved by the index without purchasing all of the stocks that make up the index by establishing an optimal portfolio. The objective of this study is to determine the optimal portfolio composition and performance by using weighted model in enhanced index tracking. Weighted model focuses on the trade-off between the excess return and the risk. The results of this study show that the optimal portfolio for the weighted model is able to outperform the Malaysia market index which is Kuala Lumpur Composite Index because of higher mean return and lower risk without purchasing all the stocks in the market index.

  18. 77 FR 57189 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ... currently approved collection. Title: TD 8560 (CO-30-92) Consolidated Returns--Stock Basis and Excess Loss...) allocating items between returns. The information will facilitate enforcement of consolidated return... completed prior to the effective data and to stop an election to use a historic loss payment pattern...

  19. Problems of Excess Capacity

    NASA Technical Reports Server (NTRS)

    Douglas, G.

    1972-01-01

    The problems of excess capacity in the airline industry are discussed with focus on the following topics: load factors; fair rate of return on investment; service-quality rivalry among airlines; pricing (fare) policies; aircraft production; and the impacts of excess capacity on operating costs. Also included is a discussion of the interrelationships among these topics.

  20. Why do speech and language therapists stay in, leave and (sometimes) return to the National Health Service (NHS)?

    PubMed

    Loan-Clarke, John; Arnold, John; Coombs, Crispin; Bosley, Sara; Martin, Caroline

    2009-01-01

    Research into recruitment, retention and return of speech and language therapists in the National Health Service (NHS) is relatively limited, particularly in respect of understanding the factors that drive employment choice decisions. To identify what factors influence speech and language therapists working in the NHS to stay, and consider leaving, but not do so. To identify what features of the NHS and alternative employers influence speech and language therapists to leave the NHS. To identify why some speech and language therapists return to the NHS after working elsewhere. A total of 516 male and female speech and language therapists, in three distinct groups (NHS stayers, leavers and returners) completed a questionnaire and gave responses to open-ended questions regarding their perceptions of the NHS and other employers. Qualitative data analysis identified reasons why individuals stayed in, left or returned to the NHS employment, and what actions could be taken by management to facilitate retention and return. Stayers value job and pension security; professional development opportunities; the work itself; and professional support. Leavers not involved in childcare left because of workload/pressure/stress; poor pay; and not being able to give good patient care. Returners returned because of flexible hours; work location; professional development; and pension provision. Stayers and returners primarily wish to see more staff in the NHS, whereas leavers would return if there were more flexibility in work arrangements. Returners were particularly hostile towards Agenda for Change. Whilst some preferences appear to require increased resources, others such as reducing bureaucracy and valuing professionals do not. The full impact of Agenda for Change has yet to be established. Predicted excess labour supply of allied health professionals and future structural changes present pressures but also possible opportunities for speech and language therapists.

  1. Idiosyncratic risk in the Dow Jones Eurostoxx50 Index

    NASA Astrophysics Data System (ADS)

    Daly, Kevin; Vo, Vinh

    2008-07-01

    Recent evidence by Campbell et al. [J.Y. Campbell, M. Lettau B.G. Malkiel, Y. Xu, Have individual stocks become more volatile? An empirical exploration of idiosyncratic risk, The Journal of Finance (February) (2001)] shows an increase in firm-level volatility and a decline of the correlation among stock returns in the US. In relation to the Euro-Area stock markets, we find that both aggregate firm-level volatility and average stock market correlation have trended upwards. We estimate a linear model of the market risk-return relationship nested in an EGARCH(1, 1)-M model for conditional second moments. We then show that traditional estimates of the conditional risk-return relationship, that use ex-post excess-returns as the conditioning information set, lead to joint tests of the theoretical model (usually the ICAPM) and of the Efficient Market Hypothesis in its strong form. To overcome this problem we propose alternative measures of expected market risk based on implied volatility extracted from traded option prices and we discuss the conditions under which implied volatility depends solely on expected risk. We then regress market excess-returns on lagged market implied variance computed from implied market volatility to estimate the relationship between expected market excess-returns and expected market risk.We investigate whether, as predicted by the ICAPM, the expected market risk is the main factor in explaining the market risk premium and the latter is independent of aggregate idiosyncratic risk.

  2. Developing trading strategies based on fractal finance: An application of MF-DFA in the context of Islamic equities

    NASA Astrophysics Data System (ADS)

    Dewandaru, Ginanjar; Masih, Rumi; Bacha, Obiyathulla Ismath; Masih, A. Mansur. M.

    2015-11-01

    We provide a new contribution to trading strategies by using multi-fractal de-trended fluctuation analysis (MF-DFA), imported from econophysics, to complement various momentum strategies. The method provides a single measure that can capture both persistency and anti-persistency in stock prices, accounting for multifractality. This study uses a sample of Islamic stocks listed in the U.S. Dow Jones Islamic market for a sample period covering 16 years starting in 1996. The findings show that the MF-DFA strategy produces monthly excess returns of 6.12%, outperforming other various momentum strategies. Even though the risk of the MF-DFA strategy may be relatively higher, it can still produce a Sharpe ratio of 0.164, which is substantially higher than that of the other strategies. When we control for the MF-DFA factor with the other factors, its pure factor return is still able to yield a monthly excess return of 1.35%. Finally, we combine the momentum and MF-DFA strategies, with the proportions of 90/10, 80/20, and 70/30 and by doing so we demonstrate that the MF-DFA measure can boost the total monthly excess returns as well as Sharpe ratio. The value added is non-linear which implies that the additional returns are associated with lower incremental risk.

  3. Fuzzy portfolio model with fuzzy-input return rates and fuzzy-output proportions

    NASA Astrophysics Data System (ADS)

    Tsaur, Ruey-Chyn

    2015-02-01

    In the finance market, a short-term investment strategy is usually applied in portfolio selection in order to reduce investment risk; however, the economy is uncertain and the investment period is short. Further, an investor has incomplete information for selecting a portfolio with crisp proportions for each chosen security. In this paper we present a new method of constructing fuzzy portfolio model for the parameters of fuzzy-input return rates and fuzzy-output proportions, based on possibilistic mean-standard deviation models. Furthermore, we consider both excess or shortage of investment in different economic periods by using fuzzy constraint for the sum of the fuzzy proportions, and we also refer to risks of securities investment and vagueness of incomplete information during the period of depression economics for the portfolio selection. Finally, we present a numerical example of a portfolio selection problem to illustrate the proposed model and a sensitivity analysis is realised based on the results.

  4. 78 FR 57218 - Proposed Collection; Comment Request for Form 8283-V

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... respect to the exterior of a building located in a registered historic district in excess of $ 10,000... revenue law. Generally, tax returns and tax return information are confidential, as required by 26 U.S.C...

  5. Transendoscopic, laser-assisted ventriculocordectomy for treatment of left laryngeal hemiplegia in horses: 22 cases (1999-2005).

    PubMed

    Henderson, Cortney E; Sullins, Kenneth E; Brown, Jennifer A

    2007-12-15

    To determine long-term effects of transendoscopic, laser-assisted ventriculocordectomy (LAVC) on airway noise and performance in horses with naturally occurring left laryngeal hemiplegia. Retrospective case series. 22 horses with left laryngeal hemiplegia treated by means of LAVC. Medical records were reviewed and initial complaint, intended use of the horse, duration of abnormal airway noise, preoperative performance level, endoscopic findings, surgical procedure, postoperative treatment, and complications were recorded. Follow-up telephone interviews with owners and trainers were conducted to determine time for return to intended use, level of postoperative performance, and percentage reduction in airway noise. All horses were examined because of excessive airway noise; 10 (45%) had concurrent exercise intolerance. Left ventriculocordectomy was performed in all 22 horses; bilateral ventriculocordectomy (right ventriculocordectomy was done 1 year later) was performed in 1 horse (5%). Complications occurred in 3 (14%) horses. Twenty (91%) horses returned to their intended use. Excessive airway noise was eliminated after surgery in 18 (82%) horses; exercise intolerance improved postoperatively in 8 of 10 horses. Three racing Thoroughbreds returned to racing; 1 additional racehorse returned to racing but required a laryngoplasty 1 year later to continue racing. Results suggested that LAVC was an effective procedure for elimination of excessive airway noise and improvement of performance in horses with left laryngeal hemiplegia.

  6. Veterans' Reactions to Release of American Hostages

    PubMed Central

    Pope, Frederick E.; Painter, Joel H.; Bergant, Carole

    1983-01-01

    Soon after the return of the hostages from Iran, the staff of the Mental Health Clinic of the Veterans Administration Outpatient Clinic, Santa Barbara, California, began noting an unusual association between veterans' feelings and the attention given the returning hostages. Of 100 veterans referred at random for diagnosis and treatment, not one had positive feelings about the reception given the returning hostages; 34 viewed the festivities and proclamations of welcome as excessive and unfair, and 12 expressed violent feelings toward the hostages, media people or members of the government. Of these 100 veterans, 52 expressed anxiety and excessive irritability, 41 were having psychic symptoms of depression and 38 reported sexual disturbances. This unusual form of stress had activated long-dormant feelings in veterans of four different wars and several generations. PMID:6858122

  7. Analysis of Historical Materiel Return Program (MRP) Credits at the 1st Marine Logistics Group Reparable Issue Point (RIP)

    DTIC Science & Technology

    2011-11-05

    45  2.  Ground Common vs. Low Density and Excess (FTE) vs. Carcass ( FTA ...47  a.  Ground Common vs. Low Density ............................. 47  b.  Excess (FTE) vs. Carcass ( FTA ...48  Figure 16.  Excess (FTE) and Carcass ( FTA ) Dollar Amounts and Percentages . 49  Figure 17.  MRP

  8. 21 CFR 211.125 - Labeling issuance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... shall be used to reconcile the quantities of labeling issued, used, and returned, and shall require... issued when such discrepancies are outside narrow preset limits based on historical operating data. Such....122(g)(2). (d) All excess labeling bearing lot or control numbers shall be destroyed. (e) Returned...

  9. 26 CFR 1.402A-1 - Designated Roth Accounts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... gross income as an amount allocable to investment in the contract is determined under section 72(e)(8... portion not includible in gross income as an amount allocable to investment in the contract is determined... preceding, however, a contribution that is returned as an excess deferral or excess contribution does not...

  10. 26 CFR 1.1502-19 - Excess loss accounts.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... have a separate return year. (2) Excess loss accounts—(i) In general. M's basis in S's stock is... nonmember. (2) Nonrecognition or deferral—(i) In general. M's income or gain under paragraph (b)(1) of this... disposition is also described in paragraph (c)(1)(i) of this section). For example, if M transfers S's stock...

  11. 26 CFR 1.1502-19 - Excess loss accounts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... have a separate return year. (2) Excess loss accounts—(i) In general. M's basis in S's stock is... nonmember. (2) Nonrecognition or deferral—(i) In general. M's income or gain under paragraph (b)(1) of this... disposition is also described in paragraph (c)(1)(i) of this section). For example, if M transfers S's stock...

  12. 26 CFR 1.1502-19 - Excess loss accounts.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... have a separate return year. (2) Excess loss accounts—(i) In general. M's basis in S's stock is... nonmember. (2) Nonrecognition or deferral—(i) In general. M's income or gain under paragraph (b)(1) of this... disposition is also described in paragraph (c)(1)(i) of this section). For example, if M transfers S's stock...

  13. 26 CFR 514.9 - Refund of excess tax withheld.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... UNDER TAX CONVENTIONS FRANCE Withholding of Tax § 514.9 Refund of excess tax withheld. (a) Years 1952... taxpayer to file an income tax return (Form 1040NB France for individuals and Form 1120NB France for... alien individual, fiduciary, or partnership) resident in France or was a French corporation, during the...

  14. Audit of Sandia Corporation`s pension plans and other prefunded benefits

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1994-04-06

    The audit disclosed that Sandia`s pension plans had $588.9 million in excess assets as of December 31, 1990, on a current value basis. If plan terminations and spin-offs occurred, at least $408.8 million of this amount could be returned to the Government without affecting the pension benefits that Sandia employees and retirees have earned. We recommended that Albuquerque take the necessary action to reduce the excess assets in the pension plans and recover the Government`s share. However, Albuquerque disagreed with the recommendation. Albuquerque justified leaving the excess assets in the pension plans to fund future plan amendments; to avoid futuremore » funding contributions; to avoid the costs and time-consuming administrative steps associated with taking action; and to prevent damaging effects on employee morale. We analyzed these points, and concluded that they should not prevent the Department from initiating action to return excess assets to the Government. Actuarial analysis of the pension plans showed that, even if certain plan adjustments were made, the plans were overfunded by $256 million as of December 31, 1991 (on an actuarial value basis).« less

  15. 32 CFR 644.533 - Contamination discovered after return of land to owner, or sale.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Contamination discovered after return of land to owner, or sale. 644.533 Section 644.533 National Defense Department of Defense (Continued) DEPARTMENT OF... Other Contamination from Proposed Excess Land and Improvements § 644.533 Contamination discovered after...

  16. Closed-Cycle Nutrient Supply For Hydroponics

    NASA Technical Reports Server (NTRS)

    Schwartzkopf, Steven H.

    1991-01-01

    Hydroponic system controls composition and feed rate of nutrient solution and recovers and recycles excess solution. Uses air pressure on bladders to transfer aqueous nutrient solution. Measures and adjusts composition of solution before it goes to hydroponic chamber. Eventually returns excess solution to one of tanks. Designed to operate in microgravity, also adaptable to hydroponic plant-growing systems on Earth.

  17. NUCLEAR REACTOR

    DOEpatents

    Breden, C.R.; Dietrich, J.R.

    1961-06-20

    A water-soluble non-volatile poison may be introduced into a reactor to nullify excess reactivity. The poison is removed by passing a side stream of the water containing the soluble poison to an evaporation chamber. The vapor phase is returned to the reactor to decrease the concentration of soluble poison and the liquid phase is returned to increase the concentration of soluble poison.

  18. 26 CFR 1.1502-98A - Coordination with section 383 generally applicable for testing dates (or members joining or...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... business credits from a pre-change consolidated return year to a post-change consolidated return year, the... 26 Internal Revenue 12 2010-04-01 2010-04-01 false Coordination with section 383 generally.... Similarly, in the case of net capital losses, general business credits, and excess foreign taxes that are...

  19. Thyroid storm

    MedlinePlus

    ... return the body temperature to normal Monitoring any excess fluid in older people with heart or kidney disease Medicines to manage agitation Vitamins and glucose The final goal of treatment is ...

  20. Logistical and Analytical Approach to a Failure Aboard the International Space Station

    NASA Technical Reports Server (NTRS)

    McDanels, Seve; Wright, M. Clara; Salazar, Victoria; Lubas, David; Tucker, Bryan

    2009-01-01

    The starboard Solar Alpha Rotary Joint (SARJ) from the International Space Station (ISS) began exhibiting off-nominal electrical demands and vibration. Examination by spacewalking astronauts revealed metallic debris contaminating the system and damage to the outboard race of the SARJ. Samples of the contamination were returned to Earth and analyzed. Excessive friction caused the nitride region of the 15-5 PH stainless steel race to spall, generating the debris and damaging the race surface. Excessive vibration and excess power was required to operate the system as a result.

  1. Excessive heat-associated gingival necrosis: a case report.

    PubMed

    Barnes, P L; Rossi-Fedele, G

    2017-09-01

    Heat-delivery devices have been associated with relatively high temperatures. Previous basic research studies suggest that the risk for periodontal tissues is negligible, as the presence of the root filling materials, amongst other factors, reduce the risk of overheating. This report describes the case of a 45 year old male, who was undergoing restorative treatment in a multi-specialty dental practice. As part of his overall treatment planning, orthograde root canal retreatment for his maxillary left incisor teeth was deemed necessary, due to chronic apical periodontitis. Following cold lateral compaction, the coronal portion of the core material was severed using a System B Heat Source (Kerr Dental, Orange, CA, USA), with the patient reporting pain as well as a burning sensation. The following day the patient was seen by a periodontist and gingival necrosis in relation to the central incisor was found. The most likely cause of the complication was considered to be excessive heat during the operative procedure. The patient was followed up for a 2-year period and the soft tissues returned to their original condition without the need for periodontal treatment. © 2017 Australian Dental Association.

  2. 76 FR 21946 - Proposed Collection; Comment Request for Form 990-BL; Schedule A (Form 990-BL), Form 6069

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-19

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently... Initial Excise Tax Return for Black Lung Benefit Trusts and Certain Related Persons, and Form 6069, Return of Excise Tax on Excess Contributions to Black Lung Benefit Trust Under Section 4953 and Computation...

  3. 26 CFR 1.6033-2 - Returns by exempt organizations (taxable years beginning after December 31, 1969) and returns by...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contractors who received in excess of $30,000 for the year for the performance of such services. (h) A... expenditures, grass roots expenditures, exempt purpose expenditures, lobbying nontaxable amount, and grass... meaning of § 1.501(h)-3(c)(7)), if the organization has an election under section 501(h) in effect for the...

  4. Endogenous time-varying risk aversion and asset returns.

    PubMed

    Berardi, Michele

    2016-01-01

    Stylized facts about statistical properties for short horizon returns in financial markets have been identified in the literature, but a satisfactory understanding for their manifestation is yet to be achieved. In this work, we show that a simple asset pricing model with representative agent is able to generate time series of returns that replicate such stylized facts if the risk aversion coefficient is allowed to change endogenously over time in response to unexpected excess returns under evolutionary forces. The same model, under constant risk aversion, would instead generate returns that are essentially Gaussian. We conclude that an endogenous time-varying risk aversion represents a very parsimonious way to make the model match real data on key statistical properties, and therefore deserves careful consideration from economists and practitioners alike.

  5. Short-term market reaction after trading halts in Chinese stock market

    NASA Astrophysics Data System (ADS)

    Xu, Hai-Chuan; Zhang, Wei; Liu, Yi-Fang

    2014-05-01

    In this paper, we study the dynamics of absolute return, trading volume and bid-ask spread after the trading halts using high-frequency data from the Shanghai Stock Exchange. We deal with all three types of trading halts, namely intraday halts, one-day halts and inter-day halts, of 203 stocks in Shanghai Stock Exchange from August 2009 to 2011. We find that absolute return, trading volume, and in case of bid-ask spread around intraday halts share the same pattern with a sharp peak and a power law relaxation after that. While for different types of trading halts, the peaks’ height and the relaxation exponents are different. From the perspective of halt reasons or halt durations, the relaxation exponents of absolute return after inter-day halts are larger than those after intraday halts and one-day halts, which implies that inter-day halts are most effective. From the perspective of price trends, the relaxation exponents of excess absolute return and excess volume for positive events are larger than those for negative events in case of intraday halts and one-day halts, implying that positive events are more effective than negative events for intraday halts and one-day halts. In contrast, negative events are more effective than positive events for inter-day halts.

  6. Is polypharmacy an independent risk factor for adverse outcomes after an emergency department visit?

    PubMed

    Salvi, Fabio; Rossi, Lorena; Lattanzio, Fabrizia; Cherubini, Antonio

    2017-03-01

    This study aimed at verifying the role of polypharmacy as an independent risk factor for adverse health outcomes in older emergency department (ED) patients. This was a large (n = 2057) sample of older ED patients (≥65 years) participating in an observational cohort study. Polypharmacy and excessive polypharmacy were defined as having 6-9 drug prescriptions and 10 or more drug prescriptions in the last 3 months, respectively. The total number of medication prescriptions was also available. Outcome measures were in-hospital mortality; 30-day ED return; ED revisit, hospital admission, and mortality at 6 months. Logistic and Cox regression models as well as receiver operating characteristic curves using the Youden index and the area under the curve were calculated. Polypharmacy and excessive polypharmacy were present in 624 (30.3 %) and 367 (17.8 %) subjects, respectively. The mean number of prescriptions in the last 3 months was 5.7 (range 0-25) drugs. Polypharmacy and, particularly, excessive polypharmacy were constantly and independently associated with worse outcomes. A cut-off of 6 had the highest value of the Youden Index in predicting the majority of the adverse outcomes considered. Polypharmacy and excessive polypharmacy are independent risk factors for adverse health outcomes after an ED visit. Further studies are needed to clarify whether drug related issues (such as non-compliance, inappropriate or suboptimal prescribing, adverse drug reactions, and drug-drug or drug-disease interactions) or underlying multimorbidity and disease severity, as well as clinical complexity and frailty, are responsible for the negative outcomes associated with polypharmacy.

  7. Magnetobraking: Use of tether electrodynamic drag for Earth return from Mars

    NASA Technical Reports Server (NTRS)

    Landis, Geoffrey A.

    1994-01-01

    It has often been proposed that a vehicle returning from Mars will use aerobraking in the Earth's atmosphere to dissipate hyperbolic excess velocity to capture into Earth orbit. Here a different system for dissipating excess velocity without expenditure of reaction mass, magnetobraking, is proposed. Magnetobraking uses the force on an electrodynamic tether in the Earth's magnetic field to produce thrust. An electrodynamic tether is deployed from the spacecraft as it approaches the Earth. The Earth's magnetic field produces a force on electrical current in the tether. If the tether is oriented perpendicularly to the Earth's magnetic field and to the direction of motion of the spacecraft, force produced by the Earth's magnetic field can be used to either brake or accelerate the spacecraft without expenditure of reaction mass. The peak acceleration on the Mars return is 0.007 m/sq sec, and the amount of braking possible is dependent on the density and current-carrying capacity of the tether, but is independent of length. A superconducting tether is required. The required critical current is shown to be within the range of superconducting technology now available in the laboratory.

  8. Method and apparatus for regenerating cold traps within liquid-metal systems

    DOEpatents

    McKee, Jr., John M.

    1976-01-01

    Oxide and hydride impurities of a liquid metal such as sodium are removed from a cold trap by heating to a temperature at which the metal hydroxide is stable in a molten state. The partial pressure of hydrogen within the system is measured to determine if excess hydride or oxide is present. Excess hydride is removed by venting hydrogen gas while excess oxide can be converted to molten hydroxide through the addition of hydrogen. The resulting, molten hydroxide is drained from the trap which is then returned to service at cold trap temperatures within the liquid-metal system.

  9. Enhanced index tracking modeling in portfolio optimization with mixed-integer programming z approach

    NASA Astrophysics Data System (ADS)

    Siew, Lam Weng; Jaaman, Saiful Hafizah Hj.; Ismail, Hamizun bin

    2014-09-01

    Enhanced index tracking is a popular form of portfolio management in stock market investment. Enhanced index tracking aims to construct an optimal portfolio to generate excess return over the return achieved by the stock market index without purchasing all of the stocks that make up the index. The objective of this paper is to construct an optimal portfolio using mixed-integer programming model which adopts regression approach in order to generate higher portfolio mean return than stock market index return. In this study, the data consists of 24 component stocks in Malaysia market index which is FTSE Bursa Malaysia Kuala Lumpur Composite Index from January 2010 until December 2012. The results of this study show that the optimal portfolio of mixed-integer programming model is able to generate higher mean return than FTSE Bursa Malaysia Kuala Lumpur Composite Index return with only selecting 30% out of the total stock market index components.

  10. Reassuringly calm? Self-reported patterns of responses to reassurance seeking in obsessive compulsive disorder.

    PubMed

    Salkovskis, Paul M; Kobori, Osamu

    2015-12-01

    The perception of threat and associated feelings of anxiety typically prompt people to seek safety; reassurance seeking is an interpersonal strategy almost universally used to reduce the immediate perception of risk. Excessive Reassurance Seeking (ERS) is considered to be particularly prominent and unequivocally counter-productive in people suffering from anxiety disorders in general and OCD in particular, producing short term relief but a longer term return and worsening of the original anxiety. We evaluated the extent and specificity of the effects of ERS in OCD and mechanisms involved in both anxiety relief and the hypothesized later return of anxiety.. Self rated effects of reassurance seeking were investigated in 153 individuals with OCD, 50 with panic disorder, and 52 healthy controls, evaluating reactions to the provision and non-provision of reassurance. Reassurance is associated with short term relief then longer term return of both discomfort and the urge to seek further reassurance in both anxious groups; healthy controls do not experience significant resurgence. Greater return of anxiety and urge to seek more reassurance were associated with higher levels of overall reassurance seeking.. The findings were based on retrospective self-report of naturally occurring episodes of ERS; prospective studies and induced behaviours are now needed. Not only is reassurance a quick fix for people experiencing OCD, but in the absence of treatment the only fix! The findings explain why reassurance seeking continues despite advice that it will worsen anxiety problems. Such advice is potentially harmful to patients and their loved ones.. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Effective Operational Assessment: A Return to the Basics

    DTIC Science & Technology

    2010-10-27

    white. Second, they concentrated on what should have been measured (an FM 5-0 rule of thumb ), such as the numbers (and names) of remaining insurgents...12 was manageable, vice ―excessive,‖ another rule of thumb . They cut right to the heart of what mattered in determining whether the insurgents...mentioned, FM 5-0 provides three excellent rules of thumb for the basics of operational assessment: ―avoid excessive analyses,‖ ―avoid … overly

  12. Wind turbine generator with improved operating subassemblies

    DOEpatents

    Cheney, Jr., Marvin C.

    1985-01-01

    A wind turbine includes a yaw spring return assembly to return the nacelle from a position to which it has been rotated by yawing forces, thus preventing excessive twisting of the power cables and control cables. It also includes negative coning restrainers to limit the bending of the flexible arms of the rotor towards the tower, and stop means on the rotor shaft to orient the blades in a vertical position during periods when the unit is upwind when the wind commences. A pendulum pitch control mechanism is improved by orienting the pivot axis for the pendulum arm at an angle to the longitudinal axis of its support arm, and excessive creep is of the synthetic resin flexible beam support for the blades is prevented by a restraining cable which limits the extent of pivoting of the pendulum during normal operation but which will permit further pivoting under abnormal conditions to cause the rotor to stall.

  13. Advances in HgCdTe APDs and LADAR Receivers

    NASA Technical Reports Server (NTRS)

    Bailey, Steven; McKeag, William; Wang, Jinxue; Jack, Michael; Amzajerdian, Farzin

    2010-01-01

    Raytheon is developing NIR sensor chip assemblies (SCAs) for scanning and staring 3D LADAR systems. High sensitivity is obtained by integrating high performance detectors with gain i.e. APDs with very low noise Readout Integrated Circuits. Unique aspects of these designs include: independent acquisition (non-gated) of pulse returns, multiple pulse returns with both time and intensity reported to enable full 3D reconstruction of the image. Recent breakthrough in device design has resulted in HgCdTe APDs operating at 300K with essentially no excess noise to gains in excess of 100, low NEP <1nW and GHz bandwidths and have demonstrated linear mode photon counting. SCAs utilizing these high performance APDs have been integrated and demonstrated excellent spatial and range resolution enabling detailed 3D imagery both at short range and long ranges. In this presentation we will review progress in high resolution scanning, staring and ultra-high sensitivity photon counting LADAR sensors.

  14. Feature discrimination/identification based upon SAR return variations

    NASA Technical Reports Server (NTRS)

    Rasco, W. A., Sr.; Pietsch, R.

    1978-01-01

    A study of the statistics of The look-to-look variation statistics in the returns recorded in-flight by a digital, realtime SAR system are analyzed. The determination that the variations in the look-to-look returns from different classes do carry information content unique to the classes was illustrated by a model based on four variants derived from four look in-flight SAR data under study. The model was limited to four classes of returns: mowed grass on a athletic field, rough unmowed grass and weeds on a large vacant field, young fruit trees in a large orchard, and metal mobile homes and storage buildings in a large mobile home park. The data population in excess of 1000 returns represented over 250 individual pixels from the four classes. The multivariant discriminant model operated on the set of returns for each pixel and assigned that pixel to one of the four classes, based on the target variants and the probability distribution function of the four variants for each class.

  15. Investigation of the daytime lunar atmosphere

    NASA Technical Reports Server (NTRS)

    Hodges, R. R., Jr.

    1985-01-01

    Lunar atmosphere research has tended to center on gases with predictably large sources and on those which have been identified by Apollo experiments. An early candidate atmospheric constituent was Ar 40 which was noted by Heyman and Yaniv to have a surface correlated component in returned soil samples, and an abundance in excess of what can be explained by potassium decay. The source of the excess argon was attributed to atmospheric argon ions which have been accelerated by solar wind fields and implanted in soil grains.

  16. 41 CFR 102-36.340 - What must we do when disposing of excess aircraft?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... operational; (ii) Data plate is available; (iii) Historical and maintenance records are available; (iv... remove and return the data plate to GSA Property Management Branch (9FBP), San Francisco, CA 94102-3434...

  17. The Point of No Return

    PubMed Central

    Logan, Gordon D.

    2015-01-01

    Bartlett (1958) described the point of no return as a point of irrevocable commitment to action, which was preceded by a period of gradually increasing commitment. As such, the point of no return reflects a fundamental limit on the ability to control thought and action. I review the literature on the point of no return, taking three perspectives. First, I consider the point of no return from the perspective of the controlled act, as a locus in the architecture and anatomy of the underlying processes. I review experiments from the stop-signal paradigm that suggest that the point of no return is located late in the response system. Then I consider the point of no return from the perspective of the act of control that tries to change the controlled act before it becomes irrevocable. From this perspective, the point of no return is a point in time that provides enough “lead time” for the act of control to take effect. I review experiments that measure the response time to the stop signal as the lead time required for response inhibition in the stop-signal paradigm. Finally, I consider the point of no return in hierarchically controlled tasks, in which there may be many points of no return at different levels of the hierarchy. I review experiments on skilled typing that suggest different points of no return for the commands that determine what is typed and the countermands that inhibit typing, with increasing commitment to action the lower the level in the hierarchy. I end by considering the point of no return in perception and thought as well as action. PMID:25633089

  18. Preschoolers who refuse to be examined. Fearful or spoiled?

    PubMed

    Schmitt, B D

    1984-05-01

    Twenty-two children (aged 2 to 5 years) who cried excessively or resisted physical examination during routine office visits initially seemed to be afraid of physicians, but eight were afraid of medical procedures, five had prolonged separation anxiety, six were manipulative, and three were afraid of men because of previous physical abuse by their fathers. Management plans were initiated for each etiological subtype. Five of eight parents whose children were afraid of medical procedures and five of six parents whose children were manipulative returned for counseling. In these cases, 100% (8/8) and 80% (4/5) of the children, respectively, made major improvement. Abused children required referral to mental health centers. Most parents of children with prolonged separation anxiety (three of five) did not consider the overdependent behavior to be a problem and therefore did not comply with treatment recommendations.

  19. The effects of behavioral and structural assumptions in artificial stock market

    NASA Astrophysics Data System (ADS)

    Liu, Xinghua; Gregor, Shirley; Yang, Jianmei

    2008-04-01

    Recent literature has developed the conjecture that important statistical features of stock price series, such as the fat tails phenomenon, may depend mainly on the market microstructure. This conjecture motivated us to investigate the roles of both the market microstructure and agent behavior with respect to high-frequency returns and daily returns. We developed two simple models to investigate this issue. The first one is a stochastic model with a clearing house microstructure and a population of zero-intelligence agents. The second one has more behavioral assumptions based on Minority Game and also has a clearing house microstructure. With the first model we found that a characteristic of the clearing house microstructure, namely the clearing frequency, can explain fat tail, excess volatility and autocorrelation phenomena of high-frequency returns. However, this feature does not cause the same phenomena in daily returns. So the Stylized Facts of daily returns depend mainly on the agents’ behavior. With the second model we investigated the effects of behavioral assumptions on daily returns. Our study implicates that the aspects which are responsible for generating the stylized facts of high-frequency returns and daily returns are different.

  20. An Overview of Rainfall-Runoff Model Types

    EPA Science Inventory

    This report explores rainfall-runoff models, their generation methods, and the categories under which they fall. Runoff plays an important role in the hydrological cycle by returning excess precipitation to the oceans and controlling how much water flows into stream systems. Mode...

  1. The point of no return: A fundamental limit on the ability to control thought and action.

    PubMed

    Logan, Gordon D

    2015-01-01

    Bartlett (1958. Thinking. New York: Basic Books) described the point of no return as a point of irrevocable commitment to action, which was preceded by a period of gradually increasing commitment. As such, the point of no return reflects a fundamental limit on the ability to control thought and action. I review the literature on the point of no return, taking three perspectives. First, I consider the point of no return from the perspective of the controlled act, as a locus in the architecture and anatomy of the underlying processes. I review experiments from the stop-signal paradigm that suggest that the point of no return is located late in the response system. Then I consider the point of no return from the perspective of the act of control that tries to change the controlled act before it becomes irrevocable. From this perspective, the point of no return is a point in time that provides enough "lead time" for the act of control to take effect. I review experiments that measure the response time to the stop signal as the lead time required for response inhibition in the stop-signal paradigm. Finally, I consider the point of no return in hierarchically controlled tasks, in which there may be many points of no return at different levels of the hierarchy. I review experiments on skilled typing that suggest different points of no return for the commands that determine what is typed and the countermands that inhibit typing, with increasing commitment to action the lower the level in the hierarchy. I end by considering the point of no return in perception and thought as well as action.

  2. Phobos Sample Return: Next Approach

    NASA Astrophysics Data System (ADS)

    Zelenyi, Lev; Martynov, Maxim; Zakharov, Alexander; Korablev, Oleg; Ivanov, Alexey; Karabadzak, George

    The Martian moons still remain a mystery after numerous studies by Mars orbiting spacecraft. Their study cover three major topics related to (1) Solar system in general (formation and evolution, origin of planetary satellites, origin and evolution of life); (2) small bodies (captured asteroid, or remnants of Mars formation, or reaccreted Mars ejecta); (3) Mars (formation and evolution of Mars; Mars ejecta at the satellites). As reviewed by Galimov [2010] most of the above questions require the sample return from the Martian moon, while some (e.g. the characterization of the organic matter) could be also answered by in situ experiments. There is the possibility to obtain the sample of Mars material by sampling Phobos: following to Chappaz et al. [2012] a 200-g sample could contain 10-7 g of Mars surface material launched during the past 1 mln years, or 5*10-5 g of Mars material launched during the past 10 mln years, or 5*1010 individual particles from Mars, quantities suitable for accurate laboratory analyses. The studies of Phobos have been of high priority in the Russian program on planetary research for many years. Phobos-88 mission consisted of two spacecraft (Phobos-1, Phobos-2) and aimed the approach to Phobos at 50 m and remote studies, and also the release of small landers (long-living stations DAS). This mission implemented the program incompletely. It was returned information about the Martian environment and atmosphere. The next profect Phobos Sample Return (Phobos-Grunt) initially planned in early 2000 has been delayed several times owing to budget difficulties; the spacecraft failed to leave NEO in 2011. The recovery of the science goals of this mission and the delivery of the samples of Phobos to Earth remain of highest priority for Russian scientific community. The next Phobos SR mission named Boomerang was postponed following the ExoMars cooperation, but is considered the next in the line of planetary exploration, suitable for launch around 2022. A possible scenario of the Boomerang mission includes the approach to Deimos prior to the landing of Phobos. The needed excess ΔV w.r.t. simple scenario (elliptical orbit à near-Phobos orbit) amounts to 0.67 km s-1 (1.6 vs 0.93 km s-1). The Boomerang mission basically repeats the Phobos-SR (2011) architecture, where the transfer-orbiting spacecraft lands on the Phobos surface and a small return vehicle launches the return capsule to Earth. We consider the Boomerang mission as an important step in Mars exploration and a direct precursor of Mars Sample Return. The following elements of the Boomerang mission might be directly employed, or serve as the prototypes for the Mars Sample return in future: Return vehicle, Earth descent module, Transfer-orbital spacecraft. We urge the development of this project for its high science value and recognize its elements as potential national contribution to an international Mars Sample Return project. Galimov E.M., Phobos sample return mission: scientific substantiation, Solar System Res., v.44, No.1, pp5-14, 2010. Chappaz L., H.J. Melosh, M. Vaguero, and K.C. Howell, Material transfer from the surface of Mars to Phobos and Deimos, 43rd Lunar and planetary Science Conference, paper 1422, 2012.

  3. Analysis of Emergency Diesel Generators Failure Incidents in Nuclear Power Plants

    NASA Astrophysics Data System (ADS)

    Hunt, Ronderio LaDavis

    In early years of operation, emergency diesel generators have had a minimal rate of demand failures. Emergency diesel generators are designed to operate as a backup when the main source of electricity has been disrupted. As of late, EDGs (emergency diesel generators) have been failing at NPPs (nuclear power plants) around the United States causing either station blackouts or loss of onsite and offsite power. These failures occurred from a specific type called demand failures. This thesis evaluated the current problem that raised concern in the nuclear industry which was averaging 1 EDG demand failure/year in 1997 to having an excessive event of 4 EDG demand failure year which occurred in 2011. To determine the next occurrence of the extreme event and possible cause to an event of such happening, two analyses were conducted, the statistical and root cause analysis. Considering the statistical analysis in which an extreme event probability approach was applied to determine the next occurrence year of an excessive event as well as, the probability of that excessive event occurring. Using the root cause analysis in which the potential causes of the excessive event occurred by evaluating, the EDG manufacturers, aging, policy changes/ maintenance practices and failure components. The root cause analysis investigated the correlation between demand failure data and historical data. Final results from the statistical analysis showed expectations of an excessive event occurring in a fixed range of probability and a wider range of probability from the extreme event probability approach. The root-cause analysis of the demand failure data followed historical statistics for the EDG manufacturer, aging and policy changes/ maintenance practices but, indicated a possible cause regarding the excessive event with the failure components. Conclusions showed the next excessive demand failure year, prediction of the probability and the next occurrence year of such failures, with an acceptable confidence level, was difficult but, it was likely that this type of failure will not be a 100 year event. It was noticeable to see that the majority of the EDG demand failures occurred within the main components as of 2005. The overall analysis of this study provided from percentages, indicated that it would be appropriate to make the statement that the excessive event was caused by the overall age (wear and tear) of the Emergency Diesel Generators in Nuclear Power Plants. Future Work will be to better determine the return period of the excessive event once the occurrence has happened for a second time by implementing the extreme event probability approach.

  4. Portfolio optimization in enhanced index tracking with goal programming approach

    NASA Astrophysics Data System (ADS)

    Siew, Lam Weng; Jaaman, Saiful Hafizah Hj.; Ismail, Hamizun bin

    2014-09-01

    Enhanced index tracking is a popular form of passive fund management in stock market. Enhanced index tracking aims to generate excess return over the return achieved by the market index without purchasing all of the stocks that make up the index. This can be done by establishing an optimal portfolio to maximize the mean return and minimize the risk. The objective of this paper is to determine the portfolio composition and performance using goal programming approach in enhanced index tracking and comparing it to the market index. Goal programming is a branch of multi-objective optimization which can handle decision problems that involve two different goals in enhanced index tracking, a trade-off between maximizing the mean return and minimizing the risk. The results of this study show that the optimal portfolio with goal programming approach is able to outperform the Malaysia market index which is FTSE Bursa Malaysia Kuala Lumpur Composite Index because of higher mean return and lower risk without purchasing all the stocks in the market index.

  5. Portfolio optimization for index tracking modelling in Malaysia stock market

    NASA Astrophysics Data System (ADS)

    Siew, Lam Weng; Jaaman, Saiful Hafizah; Ismail, Hamizun

    2016-06-01

    Index tracking is an investment strategy in portfolio management which aims to construct an optimal portfolio to generate similar mean return with the stock market index mean return without purchasing all of the stocks that make up the index. The objective of this paper is to construct an optimal portfolio using the optimization model which adopts regression approach in tracking the benchmark stock market index return. In this study, the data consists of weekly price of stocks in Malaysia market index which is FTSE Bursa Malaysia Kuala Lumpur Composite Index from January 2010 until December 2013. The results of this study show that the optimal portfolio is able to track FBMKLCI Index at minimum tracking error of 1.0027% with 0.0290% excess mean return over the mean return of FBMKLCI Index. The significance of this study is to construct the optimal portfolio using optimization model which adopts regression approach in tracking the stock market index without purchasing all index components.

  6. Mars double-aeroflyby free returns

    NASA Astrophysics Data System (ADS)

    Jesick, Mark

    2017-09-01

    Mars double-flyby free-return trajectories that pass twice through the Martian atmosphere are documented. This class of trajectories is advantageous for potential Mars atmospheric sample return missions because of its low geocentric energy at departure and arrival, because it would enable two sample collections at unique locations during different Martian seasons, and because of its lack of deterministic maneuvers. Free return opportunities are documented over Earth departure dates ranging from 2015 through 2100, with viable missions available every Earth-Mars synodic period. After constraining the maximum lift-to-drag ratio to be less than one, the minimum observed Earth departure hyperbolic excess speed is 3.23 km/s, the minimum Earth atmospheric entry speed is 11.42 km/s, and the minimum round-trip flight time is 805 days. An algorithm using simplified dynamics is developed along with a method to derive an initial estimate for trajectories in a more realistic dynamic model. Multiple examples are presented, including free returns that pass outside and inside of Mars's appreciable atmosphere.

  7. Stress fracture of ulna due to excessive push-ups.

    PubMed

    Meena, Sanjay; Rastogi, Devarshi; Solanki, Bipin; Chowdhury, Buddhadev

    2014-01-01

    Stress fractures are most common in the weight-bearing bones of the lower extremities and spine, but are rarely found in non-weight-bearing bones of the body. Stress fracture of the ulna is extremely rare. We report a case of complete stress fracture of ulna caused due to excessive push ups in a young athlete. Conservative management was successful in healing of fracture and returning this patient back to his previous activity level. Physician should have high index of suspicion, whenever they encounter a young athlete complaining of forearm pain.

  8. 25 CFR 900.245 - What obligation does the Indian tribe or tribal organization have with respect to returning...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND... improvements borne by the Indian tribe or tribal organization, in excess of $5,000 at the time of the...

  9. 25 CFR 900.245 - What obligation does the Indian tribe or tribal organization have with respect to returning...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND... improvements borne by the Indian tribe or tribal organization, in excess of $5,000 at the time of the...

  10. 25 CFR 900.245 - What obligation does the Indian tribe or tribal organization have with respect to returning...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND... improvements borne by the Indian tribe or tribal organization, in excess of $5,000 at the time of the...

  11. 25 CFR 900.245 - What obligation does the Indian tribe or tribal organization have with respect to returning...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND... improvements borne by the Indian tribe or tribal organization, in excess of $5,000 at the time of the...

  12. 25 CFR 900.245 - What obligation does the Indian tribe or tribal organization have with respect to returning...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND... improvements borne by the Indian tribe or tribal organization, in excess of $5,000 at the time of the...

  13. The Rosetta Stones of Mars — Should Meteorites be Considered as Samples of Opportunity for Mars Sample Return?

    NASA Astrophysics Data System (ADS)

    Tait, A. W.; Schröder, C.; Ashley, J. W.; Velbel, M. A.; Boston, P. J.; Carrier, B. L.; Cohen, B. A.; Bland, P. A.

    2018-04-01

    We summarize insights about Mars gained from investigating meteorites found on Mars. Certain types of meteorites can be considered standard probes inserted into the martian environment. Should they be considered for Mars Sample Return?

  14. Volatility measurement with directional change in Chinese stock market: Statistical property and investment strategy

    NASA Astrophysics Data System (ADS)

    Ma, Junjun; Xiong, Xiong; He, Feng; Zhang, Wei

    2017-04-01

    The stock price fluctuation is studied in this paper with intrinsic time perspective. The event, directional change (DC) or overshoot, are considered as time scale of price time series. With this directional change law, its corresponding statistical properties and parameter estimation is tested in Chinese stock market. Furthermore, a directional change trading strategy is proposed for invest in the market portfolio in Chinese stock market, and both in-sample and out-of-sample performance are compared among the different method of model parameter estimation. We conclude that DC method can capture important fluctuations in Chinese stock market and gain profit due to the statistical property that average upturn overshoot size is bigger than average downturn directional change size. The optimal parameter of DC method is not fixed and we obtained 1.8% annual excess return with this DC-based trading strategy.

  15. State anxiety modulates the return of fear.

    PubMed

    Kuhn, Manuel; Mertens, Gaetan; Lonsdorf, Tina B

    2016-12-01

    Current treatments for anxiety disorders are effective but limited by the high frequency of clinical relapse. Processes underlying relapse are thought to be experimentally modeled in fear conditioning experiments with return fear (ROF) inductions. Thereby reinstatement-induced ROF might be considered a model to study mechanisms underlying adversity-induced relapse. Previous studies have reported differential ROF (i.e. specific for the danger stimulus) but also generalized ROF (i.e. for safe and danger stimuli), but reasons for these divergent findings are not clear yet. Hence, the response pattern (i.e. differential or generalized) following reinstatement may be of importance for the prediction of risk or resilience for ROF. The aim of this study was to investigate state anxiety as a potential individual difference factor contributing to differentiability or generalization of return of fear. Thirty-six participants underwent instructed fear expression, extinction and ROF induction through reinstatement while physiological (skin conductance response, fear potentiated startle) and subjective measures of fear and US expectancy were acquired. Our data show that, as expected, high state anxious individuals show deficits in SCR discrimination between dangerous and safe cues after reinstatement induced ROF (i.e. generalization) as compared to low state anxious individuals. The ability to maintain discrimination under aversive circumstances is negatively associated with pathological anxiety and predictive of resilient responding while excessive generalization is a hallmark of anxiety disorders. Therefore, we suggest that experimentally induced ROF might prove useful in predicting relapse risk in clinical settings and might have implications for possible interventions for relapse prevention. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Evaluating the Generality and Limits of Blind Return-Oriented Programming Attacks

    DTIC Science & Technology

    2015-12-01

    consider a recently proposed information disclosure vulnerability called blind return-oriented programming (BROP). Under certain conditions, this...implementation disclosure attacks 15. NUMBER OF PAGES 75 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT Unclassified 18. SECURITY CLASSIFICATION OF...Science iii THIS PAGE INTENTIONALLY LEFT BLANK iv ABSTRACT We consider a recently proposed information disclosure vulnerability called blind return

  17. 7 CFR 1955.117 - Processing credit sales on program terms (housing).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... For MFH credit sales to profit or limited profit buyers, any excess earnest money deposit will be... HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY.... However, if a profit or limited profit applicant desires to earn a return, the applicant will be required...

  18. 7 CFR 1955.117 - Processing credit sales on program terms (housing).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... For MFH credit sales to profit or limited profit buyers, any excess earnest money deposit will be... HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY.... However, if a profit or limited profit applicant desires to earn a return, the applicant will be required...

  19. 7 CFR 1955.117 - Processing credit sales on program terms (housing).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... For MFH credit sales to profit or limited profit buyers, any excess earnest money deposit will be... HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY.... However, if a profit or limited profit applicant desires to earn a return, the applicant will be required...

  20. 7 CFR 1955.117 - Processing credit sales on program terms (housing).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... For MFH credit sales to profit or limited profit buyers, any excess earnest money deposit will be... HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY.... However, if a profit or limited profit applicant desires to earn a return, the applicant will be required...

  1. 7 CFR 1955.117 - Processing credit sales on program terms (housing).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... For MFH credit sales to profit or limited profit buyers, any excess earnest money deposit will be... HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY.... However, if a profit or limited profit applicant desires to earn a return, the applicant will be required...

  2. Orchids in the Bathroom: Reflections on Relocation Stress.

    ERIC Educational Resources Information Center

    Powell, William R.

    2001-01-01

    Discusses the stress factors involved in moving overseas to teach, or in returning home after an overseas assignment. Includes warning signs of relocation stress, such as becoming fearful of new situations, being reluctant to talk about the move, and finding excessive fault with new people or places. (Contains 15 references.) (NB)

  3. 77 FR 1761 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ... quantitative research and evaluation process that forecasts economic excess sector returns (over/under the... proprietary SectorSAM quantitative research and evaluation process. \\8\\ The following convictions constitute... Allocation Methodology'' (``SectorSAM''), which is a proprietary quantitative analysis, to forecast each...

  4. Co-secretion of aldosterone and cortisol by an adrenocortical carcinoma.

    PubMed

    Kurtulmus, Neslihan; Yarman, Sema; Azizlerli, Halil; Kapran, Yersu

    2004-01-01

    We report a rare case of adrenocortical carcinoma. A 26-year-old woman presented with hypokalemia and hypertension due to hyperaldosteronism. She had no signs of Cushing's syndrome. Endocrinological data showed excess of aldosterone production and nonsupressible cortisol production on 2 mg of dexamethasone. Magnetic resonance imaging showed left adrenal tumor. Transabdominal left adrenalectomy was performed and histopathological diagnosis was adrenocortical carcinoma. Her blood pressure and hypokalemia returned to normal after adrenalectomy. There is no recurrence after 36 months. We want to emphasis the importance of adrenal tests before the operation even if there are no signs of excess cortisol production.

  5. 27 CFR 70.264 - Time return deemed filed and tax considered paid.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... under this section the last day prescribed for filing a return or paying any tax. (26 U.S.C. 6513) [T.D... return filed before the last day prescribed by law or regulations for the filing thereof shall be considered as filed on such last day. For purposes of section 6511(b) (2) and (c), payment of any portion of...

  6. [Analysis of posttraumatic stress disorders in Polish soldiers who returned from stabilization mission in Iraq].

    PubMed

    Skotnicka, Justyna

    2013-01-01

    The aim of the survey was to establish whether PTSD is present among Polish soldiers returning from a one-year deployment to Iraq and an analysis of its individual symptoms. Sixty soldiers were examined, including 30 who returned from the Iraqi mission and 30 who remained in Poland. Five analysing devices were used: (IPSA), (STAI), (BDI), a PTSD questionnaire and a socio-demographical form. A significant number of soldiers experienced a traumatic event during the mission in Iraq. Although the Iraq deployment did not change the level of depression and anxiety among the two groups of soldiers, disproportions were found in the range of anger level intensity, which was significantly higher among soldiers who returned from Iraq. Stabilisation mission and the experience of a traumatic event influenced the biological and psychological functioning patterns among soldiers who returned from Iraq. The manifestations of this were emotional and physiological reactions that the soldiers experienced (nightmares, excessive sweating, increased heartbeat rate, stressful reactions in situations similar to the traumatic occurrence and intensified responses to them). However, contrary to the assumptions, it was not concluded that soldiers who returned from Iraq are suffering from PTSD.

  7. Heart rate variability and turbulence in hyperthyroidism before, during, and after treatment.

    PubMed

    Osman, Faizel; Franklyn, Jayne A; Daykin, Jacqueline; Chowdhary, Saqib; Holder, Roger L; Sheppard, Michael C; Gammage, Michael D

    2004-08-15

    Patients with subclinical and treated overt hyperthyroidism have an excess vascular mortality rate. Several symptoms and signs in overt hyperthyroidism suggest abnormality of cardiac autonomic function that may account in part for this excess mortality rate, but few studies have examined cardiac autonomic function in untreated and treated hyperthyroidism. We assessed heart rate turbulence (HRT) and time-domain parameters of heart rate variability in a large, unselected cohort of patients with overt hyperthyroidism referred to our thyroid clinic (n = 259) and compared findings with a group of normal subjects with euthyroidism (n = 440). These measures were also evaluated during antithyroid therapy (when serum-free thyroxine and triiodothyronine concentrations returned to normal but thyrotropin remained suppressed (i.e., subclinical hyperthyroidism, n = 110) and when subjects were rendered clinically and biochemically euthyroid (normal serum thyrotropin, free thyroxine and triiodothyronine concentrations, n = 219). We found that overall measures of heart rate variability and those specific for cardiac vagal modulation were attenuated in patients with overt hyperthyroidism compared with normal subjects; measurements of overall heart rate variability remained low in those with low levels of serum thyrotropin but returned to normal in patients with biochemical euthyroidism. Measurements of HRT (onset and slope) were also decreased in patients with overt hyperthyroidism, but HRT slope returned to normal values with antithyroid treatment. This study is the first to evaluate HRT in overt and treated hyperthyroidism.

  8. Transfer reservoir as a new solution for transfer of stormwater to water receivers

    NASA Astrophysics Data System (ADS)

    Malmur, Robert

    2017-11-01

    With frequent heavy rainfalls in summer in Poland and fast-melting snow in spring leading to flooding of sewage systems (due to excessive filling levels in water receivers or difficulties with temporary retention of the excess stormwater), a variety of systems are being developed to facilitate transfer of the stormwater to water receivers. Outflow of the excess stormwater is usually ensured by the use of gravitational outflow collectors that connect stormwater drains with waterways. The transfer occurs during intensive precipitation, when the excess wastewater overflows through stormwater drains and is transferred directly to water receivers in order to relieve wastewater treatment plants or to minimize diameters of sewers. These systems are useful wherever the filling levels in waterways are not very high or the sewerage system is located relatively high with respect to the water receiver i.e. outflow collector is located on a steep slope. In such cases, the stormwater that flows through a waterway cannot be returned to the outflow collector. If the gravitational flow is impossible e.g. due to the excessive filling level of water receiver, stormwater can be transferred by means of a variety of modern solutions, such as retention and transfer reservoirs. These reservoirs are supposed to ensure partial retention of the excess stormwater and transfer of this water to water receivers, either gravitationally or forced mechanically, depending on the filling level in the waterway. Furthermore, these reservoirs prevent wastewater from being returned to the system during suddenly rising levels. One of the solutions is offered by the reservoir presented in this paper. The transfer reservoir for the stormwater presented in this paper might be successfully used in modernization of current sewage systems, ensuring the reliability of operation and a more effective wastewater transfer than the systems used to date. All the reservoirs of this type are characterized by similar design and function and guarantee that the wastewater might be transferred regardless of the conditions in the water receiver. An essential feature of these reservoirs is the use of the effective method to control suction and pumping units.

  9. Reduction in excess sludge production in a dairy wastewater treatment plant via nozzle-cavitation treatment: case study of an on-farm wastewater treatment plant.

    PubMed

    Hirooka, Kayako; Asano, Ryoki; Yokoyama, Atsushi; Okazaki, Masao; Sakamoto, Akira; Nakai, Yutaka

    2009-06-01

    Nozzle-cavitation treatment was used to reduce excess sludge production in a dairy wastewater treatment plant. During the 450-d pilot-scale membrane bioreactor (MBR) operation, when 300 l of the sludge mixed liquor (1/10 of the MBR volume) was disintegrated per day by the nozzle-cavitation treatment with the addition of sodium hydrate (final concentration: 0.01% W/W) and returned to the MBR, the amount of excess sludge produced was reduced by 80% compared with that when sludge was not disintegrated. On the basis of the efficiency of CODCr removal and the ammonia oxidation reaction, it was concluded that the nozzle-cavitation treatment did not have a negative impact on the performance of the MBR. The estimation of the inorganic material balance showed that when the mass of the excess sludge was decreased, the inorganic content of the activated sludge increased and some part of the inorganic material was simultaneously solubilized in the effluent.

  10. Proposed explanations for excess injury among veterans of the Persian Gulf War and a call for greater attention from policymakers and researchers

    PubMed Central

    Bell, N; Amoroso, P; Wegman, D; Senier, L

    2001-01-01

    Introduction—Death rates among US veterans of the Persian Gulf War were lower than rates among non-deployed veterans and the US population at large, with the exception of injury deaths; returning veterans were at significantly greater risk of injury mortality. Similar patterns of excess injury mortality were documented among US and Australian veterans returning from Vietnam. In spite of these consistent findings little has been done to explain these associations and in particular to determine whether or not, and how, war related exposures influence injury risk among veterans returning home after deployments. Hypothesized pathways—Several potential pathways are proposed through which injury might be related to deployment. First, increases in injury mortality may be a consequence of depression, post-traumatic stress disorder, and symptoms of other psychiatric conditions developed after the war. Second, physical and psychological traumas experienced during the war may result in the postwar adoption of "coping" behaviors that also increase injury risk (for example, heavy drinking). Third, greater injury risk may be the indirect consequence of increased experiences of ill defined diseases and symptoms reported by many returning veterans. Fourth, veterans may experience poorer survivability for a given injury event resulting in greater mortality but not morbidity. Finally, the process that selects certain individuals for deployment may lead to a spurious association between deployment status and injury mortality by preferentially selecting individuals who are risk takers and/or exposed to greater hazards. Conclusions—More research and attention from policymakers is needed to clarify the link between deployment and postwar increased risk of injury. PMID:11289533

  11. Corn nitrogen fertilization rate tools compared over eight midwest states

    USDA-ARS?s Scientific Manuscript database

    Publicly-available nitrogen (N) rate recommendation tools are utilized to help maximize yield in corn production. These tools often fail both when N is over-applied and result in excess N being lost to the environment, or when N is under-applied and the result in decreased yield and economic returns...

  12. 77 FR 77180 - Notice of Transportation Services' OMB Designation, timely return of excess transit benefits to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-31

    ... DEPARTMENT OF TRANSPORTATION Office of the Secretary of Transportation [Docket No. DOT-OST-2013... the Treasury, and stakeholder notification of the minimum internal controls AGENCY: Office of the Secretary, DOT. ACTION: Notice. SUMMARY: On April 27, 2012, the Office of Management and Budget (OMB...

  13. 76 FR 72474 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ... has developed a proprietary SectorSAM \\TM\\ quantitative research and evaluation process that forecasts... and short portfolios as dictated by its proprietary SectorSAM quantitative research and evaluation... a proprietary quantitative analysis, to forecast each sector's excess return within a specific time...

  14. Heavy rainfall and waterborne disease outbreaks: the Walkerton example.

    PubMed

    Auld, Heather; MacIver, D; Klaassen, J

    Recent research indicates that excessive rainfall has been a significant contributor to historical waterborne disease outbreaks. The Meteorological Service of Canada, Environment Canada, provided an analysis and testimony to the Walkerton Inquiry on the excessive rainfall events, including an assessment of the historical significance and expected return periods of the rainfall amounts. While the onset of the majority of the Walkerton, Ontario, Escherichia coli O157:H7 and Campylobacter outbreak occurred several days after a heavy rainfall on May 12, the accumulated 5-d rainfall amounts from 8-12 May were particularly significant. These 5-d accumulations could, on average, only be expected once every 60 yr or more in Walkerton and once every 100 yr or so in the heaviest rainfall area to the south of Walkerton. The significant link between excess rainfall and waterborne disease outbreaks, in conjunction with other multiple risk factors, indicates that meteorological and climatological conditions need to be considered by water managers, public health officials, and private citizens as a significant risk factor for water contamination. A system to identify and project the impacts of such challenging or extreme weather conditions on water supply systems could be developed using a combination of weather/climate monitoring information and weather prediction or quantitative precipitation forecast information. The use of weather monitoring and forecast information or a "wellhead alert system" could alert water system and water supply managers on the potential response of their systems to challenging weather conditions and additional requirements to protect health. Similar approaches have recently been used by beach managers in parts of the United States to predict day-to-day water quality for beach advisories.

  15. 34 CFR 668.166 - Excess cash.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., DEPARTMENT OF EDUCATION STUDENT ASSISTANCE GENERAL PROVISIONS Cash Management § 668.166 Excess cash. (a) General. (1) The Secretary considers excess cash to be any amount of title IV, HEA program funds, other... 34 Education 3 2011-07-01 2011-07-01 false Excess cash. 668.166 Section 668.166 Education...

  16. Alcoholic Liver Disease and Liver Transplantation.

    PubMed

    Gallegos-Orozco, Juan F; Charlton, Michael R

    2016-08-01

    Excessive alcohol use is a common health care problem worldwide and is associated with significant morbidity and mortality. Alcoholic liver disease represents the second most frequent indication for liver transplantation in North America and Europe. The pretransplant evaluation of patients with alcoholic liver disease should aim at identifying those at high risk for posttransplant relapse of alcohol use disorder, as return to excessive drinking can be deleterious to graft and patient survival. Carefully selected patients with alcoholic liver disease, including those with severe alcoholic hepatitis, will have similar short-term and long-term outcomes when compared with other indications for liver transplantation. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Shuttle/TDRSS modelling and link simulation study

    NASA Technical Reports Server (NTRS)

    Braun, W. R.; Mckenzie, T. M.; Biederman, L.; Lindsey, W. C.

    1979-01-01

    A Shuttle/TDRSS S-band and Ku-band link simulation package called LinCsim was developed for the evaluation of link performance for specific Shuttle signal designs. The link models were described in detail and the transmitter distortion parameters or user constraints were carefully defined. The overall link degradation (excluding hardware degradations) relative to an ideal BPSK channel were given for various sets of user constraint values. The performance sensitivity to each individual user constraint was then illustrated. The effect of excessive Spacelab clock jitter on the return link BER performance was also investigated as was the problem of subcarrier recovery for the K-band Shuttle return link signal.

  18. Comparison between goal programming and cointegration approaches in enhanced index tracking

    NASA Astrophysics Data System (ADS)

    Lam, Weng Siew; Jamaan, Saiful Hafizah Hj.

    2013-04-01

    Index tracking is a popular form of passive fund management in stock market. Passive management is a buy-and-hold strategy that aims to achieve rate of return similar to the market return. Index tracking problem is a problem of reproducing the performance of a stock market index, without purchasing all of the stocks that make up the index. This can be done by establishing an optimal portfolio that minimizes risk or tracking error. An improved index tracking (enhanced index tracking) is a dual-objective optimization problem, a trade-off between maximizing the mean return and minimizing the tracking error. Enhanced index tracking aims to generate excess return over the return achieved by the index. The objective of this study is to compare the portfolio compositions and performances by using two different approaches in enhanced index tracking problem, which are goal programming and cointegration. The result of this study shows that the optimal portfolios for both approaches are able to outperform the Malaysia market index which is Kuala Lumpur Composite Index. Both approaches give different optimal portfolio compositions. Besides, the cointegration approach outperforms the goal programming approach because the cointegration approach gives higher mean return and lower risk or tracking error. Therefore, the cointegration approach is more appropriate for the investors in Malaysia.

  19. The best and worst of corn nitrogen rate recommendation tools used in the Midwest

    USDA-ARS?s Scientific Manuscript database

    Publicly-available nitrogen (N) rate recommendation tools are utilized to help maximize yield in corn production. These tools often fail when N is over-applied and results in excess N being lost to the environment, or when N is under-applied and results in decreased yield and economic returns. The p...

  20. 24 CFR 248.157 - Voluntary sale of housing not in excess of Federal cost limit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... costs; (5) Receive a distribution equal to an 8 percent annual return on any actual cash investment made... by a priority purchaser seeking to make an offer during either 6-month priority purchaser marketing...-based nonprofit and the offer is submitted within the marketing period established in paragraph (c)(1...

  1. 26 CFR 1.1502-19 - Excess loss accounts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... purpose contrary to the purposes of this section, to avoid the effect of the rules of this section or apply the rules of this section to avoid the effect of any other provision of the consolidated return... consolidated taxable income M's negative adjustments with respect to S's stock (e.g., under § 1.1502-32 from S...

  2. 42 CFR 137.251. - What obligation does the retroceding Self-Governance Tribe have with respect to returning...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... of improvements borne by the Self-Governance Tribe in excess of $5,000 at the time of the... 42 Public Health 1 2014-10-01 2014-10-01 false What obligation does the retroceding Self... SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.251. What...

  3. 42 CFR 137.251. - What obligation does the retroceding Self-Governance Tribe have with respect to returning...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... of improvements borne by the Self-Governance Tribe in excess of $5,000 at the time of the... 42 Public Health 1 2010-10-01 2010-10-01 false What obligation does the retroceding Self... SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.251. What...

  4. 42 CFR 137.251. - What obligation does the retroceding Self-Governance Tribe have with respect to returning...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of improvements borne by the Self-Governance Tribe in excess of $5,000 at the time of the... 42 Public Health 1 2013-10-01 2013-10-01 false What obligation does the retroceding Self... SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.251. What...

  5. 42 CFR 137.251. - What obligation does the retroceding Self-Governance Tribe have with respect to returning...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of improvements borne by the Self-Governance Tribe in excess of $5,000 at the time of the... 42 Public Health 1 2012-10-01 2012-10-01 false What obligation does the retroceding Self... SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.251. What...

  6. 42 CFR 137.251. - What obligation does the retroceding Self-Governance Tribe have with respect to returning...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... of improvements borne by the Self-Governance Tribe in excess of $5,000 at the time of the... 42 Public Health 1 2011-10-01 2011-10-01 false What obligation does the retroceding Self... SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Retrocession § 137.251. What...

  7. Stacked -gene hybrids were not found to be superior to glyphosate resistant or Non-GMO corn hybrids

    USDA-ARS?s Scientific Manuscript database

    Seed costs of modern corn hybrids genetically modified with multiple traits for insect and herbicide resistance “stacked-gene” are in excess of $100.00 US per acre. Yields and net returns per acre along with yield component data were determined for ten hybrids, four stacked-gene, four glyphosate re...

  8. Ballistic intercept missions to Comet Encke

    NASA Technical Reports Server (NTRS)

    Mumma, M. (Compiler)

    1975-01-01

    The optimum ballistic intercept of a spacecraft with the comet Encke is determined. The following factors are considered in the analysis: energy requirements, encounter conditions, targeting error, comet activity, spacecraft engineering requirements and restraints, communications, and scientific return of the mission. A baseline model is formulated which includes the basic elements necessary to estimate the scientific return for the different missions considered. Tradeoffs which have major impact on the cost and/or scientific return of a ballistic mission to comet Encke are identified and discussed. Recommendations are included.

  9. Education and Poverty Reduction in Tanzania

    ERIC Educational Resources Information Center

    Wedgwood, Ruth

    2007-01-01

    This paper reviews research on the returns to education in Tanzania, both financial and non-financial, and considers whether these returns translate into poverty reduction. It looks at reasons why achievement of high primary enrolment rates in the past did not lead to the realisation of the associated developmental outcomes, considering factors…

  10. THE INFLUENCE OF BIOTIN UPON SUSCEPTIBILITY TO MALARIA

    PubMed Central

    Trager, William

    1943-01-01

    Biotin-deficient chickens and ducks developed much more severe infections with Plasmodium lophurae than did non-deficient control animals. While a very mild degree of biotin deficiency sufficed to increase susceptibility, even an extreme degree of pantothenic acid deficiency had no effect. Biotin deficiency also increased the susceptibility of ducks to P. cathemerium. In animals infected with P. lophurae, the concentration of biotin in the plasma as well as in the red cells rose during the course of the infection, reached a peak at about the same time as the parasite number reached its peak, and then returned to normal as the infection subsided. While the administration of additional biotin to animals partially deficient in biotin could be considered a specific measure tending to lessen the severity of infection with P. lophurae, the injection of biotin into animals fed a diet adequate in this vitamin had no antimalarial effects, perhaps because the excess biotin was rapidly removed from the blood. PMID:19871304

  11. Hamstring Injuries in the Athlete: Diagnosis, Treatment, and Return to Play

    PubMed Central

    Chu, Samuel K.; Rho, Monica E.

    2016-01-01

    Hamstring injuries are very common in athletes. Acute hamstring strains can occur with high-speed running or with excessive hamstring lengthening. Athletes with proximal hamstring tendinopathy often do not report a specific inciting event; instead they develop the pathology from chronic overuse. A thorough history and examination is important to determine the appropriate diagnosis and rule out other causes of posterior thigh pain. Conservative management of hamstring strains involves a rehabilitation protocol that gradually increases intensity, range of motion and progresses to sport-specific and neuromuscular control exercises. Eccentric strengthening exercises are used for management of proximal hamstring tendinopathy. Studies investigating corticosteroid and platelet-rich plasma injections have mixed results. MRI and ultrasound are effective for identification of hamstring strains and tendinopathy, but have not demonstrated correlation with return to play. The article focuses on diagnosis, treatment and return to play considerations for acute hamstring strains and proximal hamstring tendinopathy in the athlete. PMID:27172083

  12. 41 CFR 302-3.511 - What must we consider when determining return travel for immediate family member(s) for...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... when determining return travel for immediate family member(s) for compassionate reasons prior to... determining return travel for immediate family member(s) for compassionate reasons prior to completion of the service agreement? You must determine that the public interest requires the return of the immediate family...

  13. 41 CFR 302-3.511 - What must we consider when determining return travel for immediate family member(s) for...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... when determining return travel for immediate family member(s) for compassionate reasons prior to... determining return travel for immediate family member(s) for compassionate reasons prior to completion of the service agreement? You must determine that the public interest requires the return of the immediate family...

  14. 41 CFR 302-3.511 - What must we consider when determining return travel for immediate family member(s) for...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... when determining return travel for immediate family member(s) for compassionate reasons prior to... determining return travel for immediate family member(s) for compassionate reasons prior to completion of the service agreement? You must determine that the public interest requires the return of the immediate family...

  15. 41 CFR 302-3.511 - What must we consider when determining return travel for immediate family member(s) for...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... when determining return travel for immediate family member(s) for compassionate reasons prior to... determining return travel for immediate family member(s) for compassionate reasons prior to completion of the service agreement? You must determine that the public interest requires the return of the immediate family...

  16. Two Cases of Excessive Internet Use with Comorbid Family Relationship Problems

    PubMed Central

    ŞENORMANCI, Ömer; KONKAN, Ramazan; GÜÇLÜ, Oya; ŞENORMANCI, Güliz

    2014-01-01

    Although the internet is used effectively and beneficially in every aspect of life, several users have been experiencing some problems due to excessive and uncontrolled use. While the term “internet addiction” still remains controversial, disturbed family relationships are considered to be a diagnostic criterion. The use of the internet, even in non-excessive levels, is associated with disturbance in family and social life. As considering from systemic point of view; while family relationships may be disturbed with internet addiction, people who have problems with their family relationships also may use internet excessively. This case report is composed of both the cases with excessive internet usage and those who had problems in complying with the changes in their family systems following the decrease in duration of internet usage during the treatment process. PMID:28360639

  17. Single dose of l-dopa makes extinction memories context-independent and prevents the return of fear

    PubMed Central

    Haaker, Jan; Gaburro, Stefano; Sah, Anupam; Gartmann, Nina; Lonsdorf, Tina B.; Meier, Kolja; Singewald, Nicolas; Pape, Hans-Christian; Morellini, Fabio; Kalisch, Raffael

    2013-01-01

    Traumatic events can engender persistent excessive fear responses to trauma reminders that may return even after successful treatment. Extinction, the laboratory analog of behavior therapy, does not erase conditioned fear memories but generates competing, fear-inhibitory “extinction memories” that, however, are tied to the context in which extinction occurred. Accordingly, a dominance of fear over extinction memory expression—and, thus, return of fear—is often observed if extinguished fear stimuli are encountered outside the extinction (therapy) context. We show that postextinction administration of the dopamine precursor l-dopa makes extinction memories context-independent, thus strongly reducing the return of fear in both mice and humans. Reduced fear is accompanied by decreased amygdala and enhanced ventromedial prefrontal cortex activation in both species. In humans, ventromedial prefrontal cortex activity is predicted by enhanced resting-state functional coupling of the area with the dopaminergic midbrain during the postextinction consolidation phase. Our data suggest that dopamine-dependent boosting of extinction memory consolidation is a promising avenue to improving anxiety therapy. PMID:23754384

  18. 26 CFR 1.936-4 - Intangible property income in the absence of an election out.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 1, 1983, to use the cost-plus method of pricing without reflecting a return from intangibles, but... and its affiliates do not make an election under either the cost sharing or 50/50 profit split option... disposition of any product or from the rendering of a service which is in excess of the reasonable costs it...

  19. The influence of forest management on vulnerability of forests to severe weather

    Treesearch

    Robert H. Beach; Erin O. Sills; Tzu-Ming Liu; Subhrendu Pattanayak

    2010-01-01

    Excessive wind, ice, and snow regularly cause major disturbances to forests in many parts of the world, significantly impacting both ecological conditions and economic returns to forest landowners. These events cause immediate losses for landowners, and the broken and uprooted trees left in the wake of a storm increase the risk that wildfires, disease, and pest...

  20. Mass return to the interstellar medium from highly-evolved carbon stars

    NASA Technical Reports Server (NTRS)

    Latter, W. B.; Thronson, H. A., Jr.; Hacking, P.; Bally, J.; Black, J.

    1986-01-01

    Data produced by the Infrared Astronomy Satellite (IRAS) was surveyed at the mid- and far-infrared wavelengths. Visually-identified carbon stars in the 12/25/60 micron color-color diagram were plotted, along with the location of a number of mass-losing stars that lie near the location of the carbon stars, but are not carbon rich. The final sample consisted of 619 objects, which were estimated to be contaminated by 7 % noncarbon-rich objects. The mass return rate was estimated for all evolved circumstellar envelopes. The IRAS Point Source Catalog (PSC) was also searched for the entire class of stars with excess emission. Mass-loss rates, lifetimes, and birthrates for evolved stars were also estimated.

  1. A Perishable Inventory Model with Return

    NASA Astrophysics Data System (ADS)

    Setiawan, S. W.; Lesmono, D.; Limansyah, T.

    2018-04-01

    In this paper, we develop a mathematical model for a perishable inventory with return by assuming deterministic demand and inventory dependent demand. By inventory dependent demand, it means that demand at certain time depends on the available inventory at that time with certain rate. In dealing with perishable items, we should consider deteriorating rate factor that corresponds to the decreasing quality of goods. There are also costs involved in this model such as purchasing, ordering, holding, shortage (backordering) and returning costs. These costs compose the total costs in the model that we want to minimize. In the model we seek for the optimal return time and order quantity. We assume that after some period of time, called return time, perishable items can be returned to the supplier at some returning costs. The supplier will then replace them in the next delivery. Some numerical experiments are given to illustrate our model and sensitivity analysis is performed as well. We found that as the deteriorating rate increases, returning time becomes shorter, the optimal order quantity and total cost increases. When considering the inventory-dependent demand factor, we found that as this factor increases, assuming a certain deteriorating rate, returning time becomes shorter, optimal order quantity becomes larger and the total cost increases.

  2. A new banding technique for nesting adult purple martins

    USGS Publications Warehouse

    Klimkiewicz, M.K.; Jung, P.D.

    1977-01-01

    Mery (1966) showed an almost equal sex ratio, males returned more frequently than females, over 50% of returns paired with other returns, an adult return rate of 20%, and no pair bonds maintained for more than one season. Her study lasted 13 years. Our study has shown that the return rate of locals to parent colonies is 4.1%, sex ratios are nearly equal (combination of banding and observation), return rate of locals to nearby colonies is 0.9,one pair maintained the pair bond for two years, SY females lay fewer eggs than ASY's, SY adults occasionally do not feed frequently enough to maintain the normal growth pattern of the young, SY adults often build poorly constructed nests with little or no mud, overall nest success is lower in SY adults, adults do indeed return to the same colony (19.6%) box and/or compartment, sexes are balanced in a stable colony, males or females are sometimes in excess in a new colony, SY adults are predominate in a new colony, the limiting factor in colony size is most likely the number of boxes and/or compartments available for nesting and,finally, adults and young do indeed use the boxes for roosting after nesting and fledging is complete (even boxes not their own). All of our results are tentative and subject to change after f rther study. Much additional study will be required before we can come up with conclusive answers to many of these questions about the Purple Martin.

  3. A MULTIDISCIPLINARY APPROACH TO THE REHABILITATION OF A COLLEGIATE FOOTBALL PLAYER FOLLOWING ANKLE FRACTURE: A CASE REPORT

    PubMed Central

    Kaplan, Lee D.; Musto, Tony; Gaunaurd, Ignacio A.; Gailey, Robert S.; Kelley, William P.; Alemi, Timothy J.; Espinosa, Braulio; Mandler, Eli; Scavo, Vincent A.; West, Dustin C.

    2016-01-01

    ABSTRACT Background and Purpose Multiple rehabilitation factors including overall wellness need to be considered when an athlete returns to sport after an injury. The purpose of this case report is to describe a multidisciplinary approach for return to sport of a Division I collegiate football player following a traumatic ankle fracture requiring surgical repair. The assessment and treatment approach included the use of a performance-based physical therapy outcome measure, self-reported functional abilities, body composition assessments, and nutritional counseling. Case Description A 21 year-old running back fractured his lateral malleolus due to a mechanism of injury of excessive eversion with external rotation of the ankle. Surgical intervention included an open reduction internal fixation (ORIF) of the fibula and syndesmosis. In addition to six months of rehabilitation, the patient received consultations from the team sports nutritionist specialist to provide dietary counseling and body composition testing. The Comprehensive High-level Activity Mobility Predictor-Sport (CHAMP-S), a performance-based outcome measure, self-report on the Foot and Ankle Disability Index (FADI-ADL, FADI-S), and body composition testing using whole body densitometry (BOD POD®), were administered throughout rehabilitation. Outcomes The subject was successfully rehabilitated, returned to his starting role, and subsequently was drafted by a National Football League (NFL) franchise. High-level mobility returned to above pre-injury values, achieving 105% of his preseason CHAMP-S score at discharge. Self-reported function on the FADI-ADL and FADI-Sport improved to 100% at discharge. Body fat percentages decreased (13.3% to 11.9%) and fat mass decreased (12.0 kg to 11.0kg). Lean body mass (78.1 kg to 81.5 kg) and lbm/in increased (1.14 kg/in to 1.19 kg/in). His BMI changed from 29.8 kg/m2 to 30.6 kg/m2. Discussion This case report illustrates the positive effects of a multidisciplinary approach where combining physical therapy and nutritional counseling demonstrated value with return to sport preparation and success following ankle fracture. A targeted physical therapy program combined with a personalized nutrition intervention based on body composition assessment assisted this athlete in avoiding deconditioning (atrophy, decreased aerobic capacities, and increases in body fat) often observed during postoperative care. Level of Evidence 5 PMID:27274429

  4. A MULTIDISCIPLINARY APPROACH TO THE REHABILITATION OF A COLLEGIATE FOOTBALL PLAYER FOLLOWING ANKLE FRACTURE: A CASE REPORT.

    PubMed

    Feigenbaum, Luis A; Kaplan, Lee D; Musto, Tony; Gaunaurd, Ignacio A; Gailey, Robert S; Kelley, William P; Alemi, Timothy J; Espinosa, Braulio; Mandler, Eli; Scavo, Vincent A; West, Dustin C

    2016-06-01

    Multiple rehabilitation factors including overall wellness need to be considered when an athlete returns to sport after an injury. The purpose of this case report is to describe a multidisciplinary approach for return to sport of a Division I collegiate football player following a traumatic ankle fracture requiring surgical repair. The assessment and treatment approach included the use of a performance-based physical therapy outcome measure, self-reported functional abilities, body composition assessments, and nutritional counseling. A 21 year-old running back fractured his lateral malleolus due to a mechanism of injury of excessive eversion with external rotation of the ankle. Surgical intervention included an open reduction internal fixation (ORIF) of the fibula and syndesmosis. In addition to six months of rehabilitation, the patient received consultations from the team sports nutritionist specialist to provide dietary counseling and body composition testing. The Comprehensive High-level Activity Mobility Predictor-Sport (CHAMP-S), a performance-based outcome measure, self-report on the Foot and Ankle Disability Index (FADI-ADL, FADI-S), and body composition testing using whole body densitometry (BOD POD®), were administered throughout rehabilitation. The subject was successfully rehabilitated, returned to his starting role, and subsequently was drafted by a National Football League (NFL) franchise. High-level mobility returned to above pre-injury values, achieving 105% of his preseason CHAMP-S score at discharge. Self-reported function on the FADI-ADL and FADI-Sport improved to 100% at discharge. Body fat percentages decreased (13.3% to 11.9%) and fat mass decreased (12.0 kg to 11.0kg). Lean body mass (78.1 kg to 81.5 kg) and lbm/in increased (1.14 kg/in to 1.19 kg/in). His BMI changed from 29.8 kg/m(2) to 30.6 kg/m(2). This case report illustrates the positive effects of a multidisciplinary approach where combining physical therapy and nutritional counseling demonstrated value with return to sport preparation and success following ankle fracture. A targeted physical therapy program combined with a personalized nutrition intervention based on body composition assessment assisted this athlete in avoiding deconditioning (atrophy, decreased aerobic capacities, and increases in body fat) often observed during postoperative care. 5.

  5. Biological consequences of relocating grizzly bears in the Yellowstone ecosystem

    USGS Publications Warehouse

    Blanchard, Bonnie M.; Knight, Richard R.

    1995-01-01

    Relocating grizzly bears (Ursus arctos) from human/bear conflict situations has been a standard management procedure. Using data from Yellowstone National Park, we present components of situations that may affect the outcome of a relocation. Survival rates of transported bears were lower (lx = 0.83) (P = 0.001) than those not transported (lx = 0.89). Survival was largely affected by whether the bear returned to the capture site (P = 0.029). Return rate was most affected by distance transported (P = 0.012) and age-sex group (P = 0.014). Return rates decreased at distances -75 km, and subadult females returned least (P = 0.050) often. Because of low survival and high return rates, transporting grizzly bears should be considered a final action to eliminate a conflict situation. However, transporting females must be considered a viable management technique because transports of some individuals have resulted in contributions to the population through successful reproduction.

  6. Oxygen targeting in preterm infants using the Masimo SET Radical pulse oximeter

    PubMed Central

    Johnston, Ewen D; Boyle, Breidge; Juszczak, Ed; King, Andy; Brocklehurst, Peter; Stenson, Ben J

    2011-01-01

    Background A pretrial clinical improvement project for the BOOST-II UK trial of oxygen saturation targeting revealed an artefact affecting saturation profiles obtained from the Masimo Set Radical pulse oximeter. Methods Saturation was recorded every 10 s for up to 2 weeks in 176 oxygen dependent preterm infants in 35 UK and Irish neonatal units between August 2006 and April 2009 using Masimo SET Radical pulse oximeters. Frequency distributions of % time at each saturation were plotted. An artefact affecting the saturation distribution was found to be attributable to the oximeter's internal calibration algorithm. Revised software was installed and saturation distributions obtained were compared with four other current oximeters in paired studies. Results There was a reduction in saturation values of 87–90%. Values above 87% were elevated by up to 2%, giving a relative excess of higher values. The software revision eliminated this, improving the distribution of saturation values. In paired comparisons with four current commercially available oximeters, Masimo oximeters with the revised software returned similar saturation distributions. Conclusions A characteristic of the software algorithm reduces the frequency of saturations of 87–90% and increases the frequency of higher values returned by the Masimo SET Radical pulse oximeter. This effect, which remains within the recommended standards for accuracy, is removed by installing revised software (board firmware V4.8 or higher). Because this observation is likely to influence oxygen targeting, it should be considered in the analysis of the oxygen trial results to maximise their generalisability. PMID:21378398

  7. Oxygen targeting in preterm infants using the Masimo SET Radical pulse oximeter.

    PubMed

    Johnston, Ewen D; Boyle, Breidge; Juszczak, Ed; King, Andy; Brocklehurst, Peter; Stenson, Ben J

    2011-11-01

    A pretrial clinical improvement project for the BOOST-II UK trial of oxygen saturation targeting revealed an artefact affecting saturation profiles obtained from the Masimo Set Radical pulse oximeter. Saturation was recorded every 10 s for up to 2 weeks in 176 oxygen dependent preterm infants in 35 UK and Irish neonatal units between August 2006 and April 2009 using Masimo SET Radical pulse oximeters. Frequency distributions of % time at each saturation were plotted. An artefact affecting the saturation distribution was found to be attributable to the oximeter's internal calibration algorithm. Revised software was installed and saturation distributions obtained were compared with four other current oximeters in paired studies. There was a reduction in saturation values of 87-90%. Values above 87% were elevated by up to 2%, giving a relative excess of higher values. The software revision eliminated this, improving the distribution of saturation values. In paired comparisons with four current commercially available oximeters, Masimo oximeters with the revised software returned similar saturation distributions. A characteristic of the software algorithm reduces the frequency of saturations of 87-90% and increases the frequency of higher values returned by the Masimo SET Radical pulse oximeter. This effect, which remains within the recommended standards for accuracy, is removed by installing revised software (board firmware V4.8 or higher). Because this observation is likely to influence oxygen targeting, it should be considered in the analysis of the oxygen trial results to maximise their generalisability.

  8. Efficacy of mosquito netting for sustainable small holders' cabbage production in Africa.

    PubMed

    Martin, T; Assogba-Komlan, F; Houndete, T; Hougard, J M; Chandre, F

    2006-04-01

    The efficacy of a mosquito netting to protect cabbages, Brassica oleracea L., against pests was investigated in field trials in Benin, West Africa. A polyester net covered the plants at night by using a wood armature. The net was removed during the day to prevent overheating and excessive shade, both problems of insect-proof screens used under tropical conditions. The number of all lepidopteran larvae with netting protection and foliar insecticide sprays was significantly lower than the unprotected control. The number of diamondback moth, Plutella xylostella (L.), was significantly lower with netting protection compared with foliar insecticide sprays and control. Netting treated with deltamethrin gave total protection of young plants against the aphid Lipaphis erysimi (Kaltenbach). At harvest, the number of marketable cabbages protected with untreated netting was significantly higher compared with the production with foliar insecticide sprays. The protection of cabbages with netting can be an economically viable method. Considering the price of cabbages on local markets (US dollars 1/unit), the net returns per 100 m2 were US dollars 247 by using netting, US dollars 149 by using insecticides, and US dollars 117 for controls. The net returns for using netting are based on replacing the netting each crop cycle. But netting can be reused several times, depending upon conditions, increasing the profit margin. The netting protection may be an alternative to the growing unsustainable practices of vegetable cropping in peri-urban areas of tropical countries.

  9. Biochar can be used to capture essential nutrients from dairy wastewater and improve soil physico-chemical properties

    NASA Astrophysics Data System (ADS)

    Ghezzehei, T. A.; Sarkhot, D. V.; Berhe, A. A.

    2014-09-01

    Recently, the potential for biochar use to recapture excess nutrients from dairy wastewater has been a focus of a growing number of studies. It is suggested that biochar produced from locally available excess biomass can be important in reducing release of excess nutrient elements from agricultural runoff, improving soil productivity, and long-term carbon (C) sequestration. Here we present a review of a new approach that is showing promise for the use of biochar for nutrient capture. Using batch sorption experiments, it has been shown that biochar can adsorb up to 20-43% of ammonium and 19-65% of the phosphate in flushed dairy manure in 24 h. These results suggest a potential of biochar for recovering essential nutrients from dairy wastewater and improving soil fertility if the enriched biochar is returned to soil. Based on the sorption capacity of 2.86 and 0.23 mg ammonium and phosphate, respectively, per gram of biochar and 10-50% utilization of available excess biomass, in the state of California (US) alone, 11 440 to 57 200 tonnes of ammonium-N and 920-4600 tonnes of phosphate can be captured from dairy waste each year while at the same time disposing up to 8-40 million tons of excess biomass.

  10. Fuel system for rotary distributor fuel injection pump

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klopfer, K.H.; Kelly, W.W.

    1993-06-01

    In a fuel injection pump having a drive shaft, a pump rotor driven by the drive shaft, reciprocating pumping means with periodic intake and pumping strokes to periodically receive an intake charge of fuel and deliver fuel at high pressure for fuel injection is described; a distributor head with a plurality of angularly spaced distributor outlets, the pump rotor providing a distributor rotor with a distributor port connected to the pumping means, the distributor rotor being rotatably mounted in the distributor head for sequential registration of the distributor port with the distributor outlets for distributing said high pressure delivery ofmore » fuel thereto; a fuel system for supplying fuel to the pumping means, having an end chamber at one end of the pump rotor and a fuel supply pump driven by the drive shaft and having an inlet and outlet, the supply pump outlet being connected to the end chamber for supplying fuel thereto, and a pressure regulator for regulating the fuel pressure in the end chamber; and a control valve connected between the pumping means and the end chamber and selectively opened during the intake strokes to supply fuel to the pumping means from the end chamber and during the pumping strokes to spill fuel from the pumping means into the end chamber to terminate said high pressure delivery of fuel; the improvement wherein the fuel system comprises a fuel return passage connected in series with the end chamber downstream thereof, wherein the pressure regulator is mounted in the return passage for regulating the upstream fuel pressure, including the upstream fuel pressure within the end chamber, and is connected for conducting excess fuel for return to the supply pump inlet, and wherein the supply pump is driven by the drive shaft to supply fuel at a rate exceeding the rate of said high pressure delivery of fuel for fuel injection and to provide excess fuel flow continuously through the end chamber and return passage to the pressure regulator.« less

  11. Managing Returns in a Catalog Distribution Center

    ERIC Educational Resources Information Center

    Gates, Joyce; Stuart, Julie Ann; Bonawi-tan, Winston; Loehr, Sarah

    2004-01-01

    The research team of the Purdue University in the United States developed an algorithm that considers several different factors, in addition to cost, to help catalog distribution centers process their returns more efficiently. A case study to teach the students important concepts involved in developing a solution to the returns disposition problem…

  12. Asset Allocation and Optimal Contract for Delegated Portfolio Management

    NASA Astrophysics Data System (ADS)

    Liu, Jingjun; Liang, Jianfeng

    This article studies the portfolio selection and the contracting problems between an individual investor and a professional portfolio manager in a discrete-time principal-agent framework. Portfolio selection and optimal contracts are obtained in closed form. The optimal contract was composed with the fixed fee, the cost, and the fraction of excess expected return. The optimal portfolio is similar to the classical two-fund separation theorem.

  13. The Retrograde of Shipping Containers from Afghanistan

    DTIC Science & Technology

    2013-04-01

    detention costs; however, many are still marked with carrier identification markings. To mitigate the problem, Mobile Container Assistance Teams ( MCATs ...comply with the USCENTCOM letter of instruction, the MCATs inventoried containers and locations in theater, with the intent to return carrier...Expeditionary Disposal Remediation Team (EDRT) out to the COPs and FOBs to linkup with MCATs , and the unit CCO to assess all excess containers.96

  14. 11 CFR 103.3 - Deposit of receipts and disbursements (2 U.S.C. 432(h)(1)).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... forth in 11 CFR 110.1 or 110.2, and contributions which do not appear to be excessive on their face, but... receipts by a political committee shall be deposited in account(s) established pursuant to 11 CFR 103.2, except that any contribution may be, within 10 days of the treasurer's receipt, returned to the...

  15. 26 CFR 1.6038-2 - Information returns required of United States persons with respect to annual accounting periods...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 6038(c)(1)(B) reduction 34,000 (e) Dividend paid by N to M 45,000 (f) Accumulated profits of N as... profits described in section 902(a) (determined without regard to the reduction provided under section... foreign income, war profits, and excess profits taxes are determined on the basis of an accounting period...

  16. Diagnosis and outcome of a dog with iatrogenic hyperadrenocorticism and secondary pulmonary mineralization.

    PubMed

    Blois, Shauna L; Caron, Isabelle; Mitchell, Colleen

    2009-04-01

    A 6-year-old, spayed female dog was evaluated for a history of chronic coughing, excessive panting, and lethargy. Iatrogenic hyperadrenocorticism was diagnosed, and pulmonary mineralization was documented with a 99m Technitium-methylene diphosphonate (99mTc-MDP) scan. Blood gas analysis showed hypoxia. Clinical signs resolved and blood gas values returned to normal when corticosteroid therapy was discontinued.

  17. Diagnosis and outcome of a dog with iatrogenic hyperadrenocorticism and secondary pulmonary mineralization

    PubMed Central

    Blois, Shauna L.; Caron, Isabelle; Mitchell, Colleen

    2009-01-01

    A 6-year-old, spayed female dog was evaluated for a history of chronic coughing, excessive panting, and lethargy. Iatrogenic hyperadrenocorticism was diagnosed, and pulmonary mineralization was documented with a 99mTechnitium-methylene diphosphonate (99mTc-MDP) scan. Blood gas analysis showed hypoxia. Clinical signs resolved and blood gas values returned to normal when corticosteroid therapy was discontinued. PMID:19436448

  18. Hamstring Injuries in the Athlete: Diagnosis, Treatment, and Return to Play.

    PubMed

    Chu, Samuel K; Rho, Monica E

    2016-01-01

    Hamstring injuries are very common in athletes. Acute hamstring strains can occur with high-speed running or with excessive hamstring lengthening. Athletes with proximal hamstring tendinopathy often do not report a specific inciting event; instead, they develop the pathology from chronic overuse. A thorough history and physical examination is important to determine the appropriate diagnosis and rule out other causes of posterior thigh pain. Conservative management of hamstring strains involves a rehabilitation protocol that gradually increases intensity and range of motion, and progresses to sport-specific and neuromuscular control exercises. Eccentric strengthening exercises are used for management of proximal hamstring tendinopathy. Studies investigating corticosteroid and platelet-rich plasma injections have mixed results. Magnetic resonance imaging and ultrasound are effective for identification of hamstring strains and tendinopathy but have not demonstrated correlation with return to play. The article focuses on diagnosis, treatment, and return-to-play considerations for acute hamstring strains and proximal hamstring tendinopathy in the athlete.

  19. Using the Internal Rate of Return Method to Consider the Potential Degree Offerings of a Liberal Arts College

    ERIC Educational Resources Information Center

    Doss, D. Adrian; Troxel, Stacy; Sumrall, Bill

    2010-01-01

    This paper considered the case of a liberal arts institution of higher learning that is hoping to improve its market competitiveness through the addition of either a graduate certificate program in human resources or the addition of a full graduate degree in human resources. An examination of internal rate of return financial value capital…

  20. River sedimentation and channel bed characteristics in northern Ethiopia

    NASA Astrophysics Data System (ADS)

    Demissie, Biadgilgn; Billi, Paolo; Frankl, Amaury; Haile, Mitiku; Lanckriet, Sil; Nyssen, Jan

    2016-04-01

    Excessive sedimentation and flood hazard are common in ephemeral streams which are characterized by flashy floods. The purposes of this study was to investigate the temporal variability of bio-climatic factors in controlling sediment supply to downstream channel reaches and the effect of bridges on local hydro-geomorphic conditions in causing the excess sedimentation and flood hazard in ephemeral rivers of the Raya graben (northern Ethiopia). Normalized Difference Vegetation Index (NDVI) was analyzed for the study area using Landsat imageries of 1972, 1986, 2000, 2005, 2010, and 2012). Middle term, 1993-2011, daily rainfall data of three meteorological stations, namely, Alamata, Korem and Maychew, were considered to analyse the temporal trends and to calculate the return time intervals of rainfall intensity in 24 hours for 2, 5, 10 and 20 years using the log-normal and the Gumbel extreme events method. Streambed gradient and bed material grain size were measured in 22 river reaches (at bridges and upstream). In the study catchments, the maximum NDVI values were recorded in the time interval from 2000 to 2010, i.e. the decade during which the study bridges experienced the most severe excess sedimentation problems. The time series analysis for a few rainfall parameters do not show any evidence of rainfall pattern accountable for an increase in sediment delivery from the headwaters nor for the generation of higher floods with larger bedload transport capacities. Stream bed gradient and bed material grain size data were measured in order to investigate the effect of the marked decrease in width from the wide upstream channels to the narrow recently constructed bridges. The study found the narrowing of the channels due to the bridges as the main cause of the thick sedimentation that has been clogging the study bridges and increasing the frequency of overbank flows during the last 15 years. Key terms: sedimentation, ephemeral streams, sediment size, bridge clogging

  1. EXPERIMENTS IN LITHOGRAPHY FROM REMOTE SENSOR IMAGERY.

    USGS Publications Warehouse

    Kidwell, R. H.; McSweeney, J.; Warren, A.; Zang, E.; Vickers, E.

    1983-01-01

    Imagery from remote sensing systems such as the Landsat multispectral scanner and return beam vidicon, as well as synthetic aperture radar and conventional optical camera systems, contains information at resolutions far in excess of that which can be reproduced by the lithographic printing process. The data often require special handling to produce both standard and special map products. Some conclusions have been drawn regarding processing techniques, procedures for production, and printing limitations.

  2. 26 CFR 1.6050I-2 - Returns relating to cash in excess of $10,000 received as bail by court clerks.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 of the United States Code); (3) Money laundering (as defined in section 1956 or 1957 of title 18... are customarily used and accepted as money in the country in which issued; and (2) A cashier's check..., or money order having a face amount of not more than $10,000. Specified criminal offense means— (1) A...

  3. Command and Control Options for Joint Logistics

    DTIC Science & Technology

    2011-03-24

    PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 24-03-2011 2. REPORT TYPE Strategy Research Project 3. DATES...point due to excessive government spending.6 The result will most-assuredly be a tightening of pocketbooks , a call for efficiencies and a smaller...procedures and capabilities of Service component logistics processes to build the logistics common operating picture and associated actions. 8. Integrated

  4. A Classification and Analysis of Contracting Literature

    DTIC Science & Technology

    1989-12-01

    Pricing Model ( CAPM . This is a model designed by investment analysts to determine required rates of return given the systematic risk of a company. The...For the amount of risk they take, these profit margins were not excessively high. The author examined profitability in terms of the Capital Asset ...taxonomy was applied was limited , the results were necessarily qualified. However, at the least this application provided areas for further research

  5. Treatment of severe poison ivy: a randomized, controlled trial of long versus short course oral prednisone.

    PubMed

    Curtis, Gabrielle; Lewis, Amy C

    2014-12-01

    Toxidendron (poison ivy, oak, and sumac) contact dermatitis is a common complaint in the outpatient primary care setting with little evidence-based guidance on best treatment duration. This randomized, controlled trial examined the efficacy and side effects of a 5-day regimen of 40 mg oral prednisone daily (short course) compared to the same 5-day regimen followed by a prednisone taper of 30 mg daily for 2 days, 20 mg daily for 2 days, 10 mg daily for 2 days, and 5 mg daily for 4 days over a total of 15 days (long course) in patients with severe poison ivy dermatitis. In 49 patients with severe poison ivy, non-adherence rates, rash return, medication side effects, and time to improvement and complete healing of the rash were not significantly different between the two groups. Patients receiving the long course regimen were significantly less likely to utilize other medications (22.7% vs. 55.6%, P = 0.02, number needed to treat 3.05). This study suggests that a longer course prescription may save patients' time and exposure to excess medication in the treatment of severe poison ivy. Application of this information to clinical practice will save return visits and reduce excess non-prescription medication administration to individual patients.

  6. Treatment of Severe Poison Ivy: A Randomized, Controlled Trial of Long Versus Short Course Oral Prednisone

    PubMed Central

    Curtis, Gabrielle; Lewis, Amy C.

    2014-01-01

    Background Toxidendron (poison ivy, oak, and sumac) contact dermatitis is a common complaint in the outpatient primary care setting with little evidence-based guidance on best treatment duration. Methods This randomized, controlled trial examined the efficacy and side effects of a 5-day regimen of 40 mg oral prednisone daily (short course) compared to the same 5-day regimen followed by a prednisone taper of 30 mg daily for 2 days, 20 mg daily for 2 days, 10 mg daily for 2 days, and 5 mg daily for 4 days over a total of 15 days (long course) in patients with severe poison ivy dermatitis. Results In 49 patients with severe poison ivy, non-adherence rates, rash return, medication side effects, and time to improvement and complete healing of the rash were not significantly different between the two groups. Patients receiving the long course regimen were significantly less likely to utilize other medications (22.7% vs. 55.6%, P = 0.02, number needed to treat 3.05). Conclusions This study suggests that a longer course prescription may save patients’ time and exposure to excess medication in the treatment of severe poison ivy. Application of this information to clinical practice will save return visits and reduce excess non-prescription medication administration to individual patients. PMID:25247016

  7. Extreme value modelling of Ghana stock exchange index.

    PubMed

    Nortey, Ezekiel N N; Asare, Kwabena; Mettle, Felix Okoe

    2015-01-01

    Modelling of extreme events has always been of interest in fields such as hydrology and meteorology. However, after the recent global financial crises, appropriate models for modelling of such rare events leading to these crises have become quite essential in the finance and risk management fields. This paper models the extreme values of the Ghana stock exchange all-shares index (2000-2010) by applying the extreme value theory (EVT) to fit a model to the tails of the daily stock returns data. A conditional approach of the EVT was preferred and hence an ARMA-GARCH model was fitted to the data to correct for the effects of autocorrelation and conditional heteroscedastic terms present in the returns series, before the EVT method was applied. The Peak Over Threshold approach of the EVT, which fits a Generalized Pareto Distribution (GPD) model to excesses above a certain selected threshold, was employed. Maximum likelihood estimates of the model parameters were obtained and the model's goodness of fit was assessed graphically using Q-Q, P-P and density plots. The findings indicate that the GPD provides an adequate fit to the data of excesses. The size of the extreme daily Ghanaian stock market movements were then computed using the value at risk and expected shortfall risk measures at some high quantiles, based on the fitted GPD model.

  8. Advances in LADAR Components and Subsystems at Raytheon

    NASA Technical Reports Server (NTRS)

    Jack, Michael; Chapman, George; Edwards, John; McKeag, William; Veeder, Tricia; Wehner, Justin; Roberts, Tom; Robinson, Tom; Neisz, James; Andressen, Cliff; hide

    2012-01-01

    Raytheon is developing NIR sensor chip assemblies (SCAs) for scanning and staring 3D LADAR systems. High sensitivity is obtained by integrating high performance detectors with gain, i.e., APDs with very low noise Readout Integrated Circuits (ROICs). Unique aspects of these designs include: independent acquisition (non-gated) of pulse returns, multiple pulse returns with both time and intensity reported to enable full 3D reconstruction of the image. Recent breakthrough in device design has resulted in HgCdTe APDs operating at 300K with essentially no excess noise to gains in excess of 100, low NEP <1nW and GHz bandwidths and have demonstrated linear mode photon counting. SCAs utilizing these high performance APDs have been integrated and demonstrated excellent spatial and range resolution enabling detailed 3D imagery both at short range and long ranges. In the following we will review progress in real-time 3D LADAR imaging receiver products in three areas: (1) scanning 256 x 4 configuration for the Multi-Mode Sensor Seeker (MMSS) program and (2) staring 256 x 256 configuration for the Autonomous Landing and Hazard Avoidance Technology (ALHAT) lunar landing mission and (3) Photon-Counting SCAs which have demonstrated a dramatic reduction in dark count rate due to improved design, operation and processing.

  9. Return to Play Following Anterior Shoulder Dislocation and Stabilization Surgery.

    PubMed

    Donohue, Michael A; Owens, Brett D; Dickens, Jonathan F

    2016-10-01

    Anterior shoulder instability in athletes may lead to time lost from participation and decreases in level of play. Contact, collision, and overhead athletes are at a higher risk than others. Athletes may successfully be returned to play but operative stabilization should be considered for long-term treatment of recurrent instability. Open and arthroscopic stabilization procedures for athletes with less than 20% to 25% bone loss improve return to play rates and decrease recurrent instability, with a slightly lower recurrence with open stabilization. For athletes with greater than 20% to 25% bone loss, an open osseous augmentation procedure should be considered. Published by Elsevier Inc.

  10. Work-Related Factors Considered by Sickness-Absent Employees When Estimating Timeframes for Returning to Work

    PubMed Central

    Choi, YoonSun

    2016-01-01

    Introduction Work-related factors have been found to be influential in shaping a number of return-to-work outcomes including return-to-work expectations. Based on the idea that work-related factors have the potential for modification through workplace-based initiatives, this study involved a detailed examination of work-related factors referenced by workers as being taken into consideration when estimating timeframes for returning to work. Methods Focus groups were conducted with 30 employees, currently off work (≤ 3 months) due to a musculoskeletal condition. During the focus groups, participants wrote and spoke about the factors that they considered when forming their expectations for returning to work. Data were subjected to thematic content analysis. Results Discussions revealed that participants’ considerations tended to differ depending on whether or not they had a job to return to. Those with jobs (n = 23) referenced specific influences such as working relationships, accommodations, physical and practical limitations, as well as concerns about their ability to do their job. Those without a job to return to (n = 7) talked about the ways they would go about finding work, and how long they thought this would take. Both groups mentioned the influence of wanting to find the “right” job, retraining and being limited due to the need for income. Conclusion Findings indicate that employees reference numerous work-related factors when estimating their timeframes for returning to work, and that many of these have been previously identified as relating to other return-to-work outcomes. Findings suggest the potential to improve return-to-work expectation through addressing work-related influences, and helping people work through the tasks they need to complete in order to move forward in the return-to-work process. PMID:27706194

  11. Work-Related Factors Considered by Sickness-Absent Employees When Estimating Timeframes for Returning to Work.

    PubMed

    Young, Amanda E; Choi, YoonSun

    2016-01-01

    Work-related factors have been found to be influential in shaping a number of return-to-work outcomes including return-to-work expectations. Based on the idea that work-related factors have the potential for modification through workplace-based initiatives, this study involved a detailed examination of work-related factors referenced by workers as being taken into consideration when estimating timeframes for returning to work. Focus groups were conducted with 30 employees, currently off work (≤ 3 months) due to a musculoskeletal condition. During the focus groups, participants wrote and spoke about the factors that they considered when forming their expectations for returning to work. Data were subjected to thematic content analysis. Discussions revealed that participants' considerations tended to differ depending on whether or not they had a job to return to. Those with jobs (n = 23) referenced specific influences such as working relationships, accommodations, physical and practical limitations, as well as concerns about their ability to do their job. Those without a job to return to (n = 7) talked about the ways they would go about finding work, and how long they thought this would take. Both groups mentioned the influence of wanting to find the "right" job, retraining and being limited due to the need for income. Findings indicate that employees reference numerous work-related factors when estimating their timeframes for returning to work, and that many of these have been previously identified as relating to other return-to-work outcomes. Findings suggest the potential to improve return-to-work expectation through addressing work-related influences, and helping people work through the tasks they need to complete in order to move forward in the return-to-work process.

  12. Modeling the greenhouse gas budget of straw returning in China: feasibility of mitigation and countermeasures.

    PubMed

    Lu, Fei; Wang, Xiao-Ke; Han, Bing; Ouyang, Zhi-Yun; Zheng, Hua

    2010-05-01

    Straw returning is considered to be one of the most promising carbon sequestration measures in China's cropland. A compound model, namely "Straw Returning and Burning Model-Expansion" (SRBME), was built to estimate the net mitigation potential, economic benefits, and air pollutant reduction of straw returning. Three scenarios, that is, baseline, "full popularization of straw returning (FP)," and "full popularization of straw returning and precision fertilization (FP + P)," were set to reflect popularization of straw returning. The results of the SRBME indicated that (1) compared with the soil carbon sequestration of 13.37 Tg/yr, the net mitigation potentials, which were 6.328 Tg/yr for the FP scenario and 9.179 Tg/yr for the FP + P scenario, had different trends when the full budget of the greenhouse gases was considered; (2) when the feasibility in connection with greenhouse gas (GHG) mitigation, economic benefits, and environmental benefits was taken into consideration, straw returning was feasible in 15 provinces in the FP scenario, with a total net mitigation potential of 7.192 TgCe/yr and the total benefits of CNY 1.473 billion (USD 216.6 million); (3) in the FP + P scenario, with the implementation of precision fertilization, straw returning was feasible in 26 provinces with a total net mitigation potential of 10.39 TgCe/yr and the total benefits of CNY 5.466 billion (USD 803.8 million); (4) any extent of change in the treatment of straw from being burnt to being returned would contribute to air pollution reduction; (5) some countermeasures, such as CH(4) reduction in rice paddies, precision fertilization, financial support, education and propaganda, would promote the feasibility of straw returning as a mitigation measure.

  13. Asteroid (Flora and Eros) sample-return missions via solar electric propulsion

    NASA Technical Reports Server (NTRS)

    Friedlander, A. L.

    1971-01-01

    The characteristics and capabilities of solar electric propulsion for performing sample-return missions to the asteroids Flora and Eros are considered. Trajectory/payload analysis and mission design tradeoff options are emphasized.

  14. Comorbidities as a driver of the excess costs of community-acquired pneumonia in U.S. commercially-insured working age adults

    PubMed Central

    2012-01-01

    Background Adults with certain comorbid conditions have a higher risk of pneumonia than the overall population. If treatment of pneumonia is more costly in certain predictable situations, this would affect the value proposition of populations for pneumonia prevention. We estimate the economic impact of community-acquired pneumonia (CAP) for adults with asthma, diabetes, chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF) in a large U.S. commercially-insured working age population. Methods Data sources consisted of 2003 through 2007 Thomson Reuters MarketScan Commercial Claims and Encounters and Thomson Reuters Health Productivity and Management (HPM) databases. Pneumonia episodes and selected comorbidities were identified by ICD-9-CM diagnosis codes. By propensity score matching, controls were identified for pneumonia patients. Excess direct medical costs and excess productivity cost were estimated by generalized linear models (GLM). Results We identified 402,831 patients with CAP between 2003 through 2007, with 25,560, 32,677, 16,343, and 5,062 episodes occurring in patients with asthma, diabetes, COPD and CHF, respectively. Mean excess costs (and standard error, SE) of CAP were $14,429 (SE=44) overall. Mean excess costs by comorbidity subgroup were lowest for asthma ($13,307 (SE=123)), followed by diabetes ($21,395 (SE=171)) and COPD ($23,493 (SE=197)); mean excess costs were highest for patients with CHF ($34,436 (SE=549)). On average, indirect costs comprised 21% of total excess costs, ranging from 8% for CHF patients to 27% for COPD patients. Conclusions Compared to patients without asthma, diabetes, COPD, or CHF, the excess cost of CAP is nearly twice as high for patients with diabetes and COPD and nearly three times as high for patients with CHF. Indirect costs made up a significant but varying portion of excess CAP costs. Returns on prevention of pneumonia would therefore be higher in adults with these comorbidities. PMID:23113880

  15. Comorbidities as a driver of the excess costs of community-acquired pneumonia in U.S. commercially-insured working age adults.

    PubMed

    Polsky, Daniel; Bonafede, Machaon; Suaya, Jose A

    2012-10-31

    Adults with certain comorbid conditions have a higher risk of pneumonia than the overall population. If treatment of pneumonia is more costly in certain predictable situations, this would affect the value proposition of populations for pneumonia prevention. We estimate the economic impact of community-acquired pneumonia (CAP) for adults with asthma, diabetes, chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF) in a large U.S. commercially-insured working age population. Data sources consisted of 2003 through 2007 Thomson Reuters MarketScan Commercial Claims and Encounters and Thomson Reuters Health Productivity and Management (HPM) databases. Pneumonia episodes and selected comorbidities were identified by ICD-9-CM diagnosis codes. By propensity score matching, controls were identified for pneumonia patients. Excess direct medical costs and excess productivity cost were estimated by generalized linear models (GLM). We identified 402,831 patients with CAP between 2003 through 2007, with 25,560, 32,677, 16,343, and 5,062 episodes occurring in patients with asthma, diabetes, COPD and CHF, respectively. Mean excess costs (and standard error, SE) of CAP were $14,429 (SE=44) overall. Mean excess costs by comorbidity subgroup were lowest for asthma ($13,307 (SE=123)), followed by diabetes ($21,395 (SE=171)) and COPD ($23,493 (SE=197)); mean excess costs were highest for patients with CHF ($34,436 (SE=549)). On average, indirect costs comprised 21% of total excess costs, ranging from 8% for CHF patients to 27% for COPD patients. Compared to patients without asthma, diabetes, COPD, or CHF, the excess cost of CAP is nearly twice as high for patients with diabetes and COPD and nearly three times as high for patients with CHF. Indirect costs made up a significant but varying portion of excess CAP costs. Returns on prevention of pneumonia would therefore be higher in adults with these comorbidities.

  16. Combined compressed air storage-low BTU coal gasification power plant

    DOEpatents

    Kartsounes, George T.; Sather, Norman F.

    1979-01-01

    An electrical generating power plant includes a Compressed Air Energy Storage System (CAES) fueled with low BTU coal gas generated in a continuously operating high pressure coal gasifier system. This system is used in coordination with a continuously operating main power generating plant to store excess power generated during off-peak hours from the power generating plant, and to return the stored energy as peak power to the power generating plant when needed. The excess coal gas which is produced by the coal gasifier during off-peak hours is stored in a coal gas reservoir. During peak hours the stored coal gas is combined with the output of the coal gasifier to fuel the gas turbines and ultimately supply electrical power to the base power plant.

  17. A Dielectric-Filled Waveguide Antenna Element for 3D Imaging Radar in High Temperature and Excessive Dust Conditions.

    PubMed

    Xu, Ding; Li, Zhiping; Chen, Xianzhong; Wang, Zhengpeng; Wu, Jianhua

    2016-08-22

    Three-dimensional information of the burden surface in high temperature and excessive dust industrial conditions has been previously hard to obtain. This paper presents a novel microstrip-fed dielectric-filled waveguide antenna element which is resistant to dust and high temperatures. A novel microstrip-to-dielectric-loaded waveguide transition was developed. A cylinder and cuboid composite structure was employed at the terminal of the antenna element, which improved the return loss performance and reduced the size. The proposed antenna element was easily integrated into a T-shape multiple-input multiple-output (MIMO) imaging radar system and tested in both the laboratory environment and real blast furnace environment. The measurement results show that the proposed antenna element works very well in industrial 3D imaging radar.

  18. Plasmodium vivax malaria in a Romanian traveller returning from Greece, August 2011.

    PubMed

    Florescu, S A; Popescu, C P; Calistru, P; Ceausu, E; Nica, M; Toderan, A; Zaharia, M; Parola, P

    2011-09-01

    In August 2011, a Plasmodium vivax malaria infection was diagnosed in a Romanian traveller returning from Greece. This case together with several reports over the past decade of autochthonous cases in Greece highlight that malaria should be considered as differential diagnosis in symptomatic travellers returning from this country. Travellers may serve as sentinels of emerging vector-borne diseases.

  19. Cholera with severe renal failure in an Italian tourist returning from Cuba, July 2013.

    PubMed

    Mascarello, M; Deiana, M L; Maurel, C; Lucarelli, C; Luzzi, I; Luzzati, R

    2013-08-29

    In July 2013, an Italian tourist returning from Cuba was hospitalised in Trieste, Italy, for cholera caused by Vibrio cholerae O1 serotype Ogawa with severe renal failure. An outbreak of cholera was reported in Cuba in January 2013. Physicians should consider the diagnosis of cholera in travellers returning from Cuba presenting with acute watery diarrhoea.

  20. A Proposed Return-to-Sport Program for Patients With Midportion Achilles Tendinopathy: Rationale and Implementation.

    PubMed

    Silbernagel, Karin Grävare; Crossley, Kay M

    2015-11-01

    Synopsis Achilles tendinopathy is a common overuse injury in athletes involved in running and jumping activities and sports. The intervention with the highest level of evidence is exercise therapy, and it is recommended that all patients initially be treated with exercise for at least 3 months prior to considering other treatment options. Recovery from Achilles tendinopathy can take up to a year, and there is a high propensity for recurrence, especially during the return-to-sport phase. The extent of the tendon injury, the age and sex of the athlete, the magnitude of pain/symptoms, the extent of impairments, and the demands of the sport all need to be considered when planning for return to sport. This clinical commentary describes an approach to return to sport for patients with midportion Achilles tendinopathy. The aim of the return-to-sport program is to facilitate the decision-making process in returning an athlete with midportion Achilles tendinopathy back to full sport participation and to minimize the chances for recurrence of the injury. J Orthop Sports Phys Ther 2015;45(11):876-886. Epub 21 Sep 2015. doi:10.2519/jospt.2015.5885.

  1. Decentralized method for utility regulation: a comment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sharkey, W.W.

    The author comments on the article by Loeb and Magat in this journal issue (P 399); he feels their idea is worthy of more-detailed examination on an industry-specific level. He confines his comments, however, to a more-general comparison of the Loeb-Magat (L-M) scheme, traditional rate-of-return regulation, and pure franchise bidding. The basic L-M proposal consists of two parts. First it is shown that if a utility is subsidized by an amount corresponding to total consumer surplus, then it will have the incentive to pursue cost-minimizing behavior and to set its price equal to the marginal cost of production. Mr. Sharkeymore » believes that this pure subsidy scheme would be wholly unworkable in practice. The second part of the L-M proposal consists of the subsidy scheme combined with either franchise bidding or a lump-sum tax. Mr. Sharkey feels that this proposal has considerable merit if conditions exist such that the net subsidy paid to the utility is sufficiently small; net subsidy is defined as the excess of the actual subsidy plus revenues of the firm over the total cost of production. Thus, the net subsidy is the excess profit the utility receives compared to a utility perfectly regulated by traditional means. Mr. Sharkey elaborates on some of his objections to the L-M proposal for cases in which the net subsidy is large. Then, he briefly considers the characteristics of a natural monopoly market which could potentially be regulated by a combined subsidy-franchise-tax scheme.« less

  2. Non-inflammatory destructive periodontal disease: a clinical, microbiological, immunological and genetic investigation

    PubMed Central

    REPEKE, Carlos Eduardo; CARDOSO, Cristina Ribeiro; CLAUDINO, Marcela; SILVEIRA, Elcia Maria; TROMBONE, Ana Paula Favaro; CAMPANELLI, Ana Paula; SILVA, João Santana; MARTINS JÚNIOR, Walter; GARLET, Gustavo Pompermaier

    2012-01-01

    Periodontitis comprises a group of multifactorial diseases in which periodontopathogens accumulate in dental plaque and trigger host chronic inflammatory and immune responses against periodontal structures, which are determinant to the disease outcome. Although unusual cases of non-inflammatory destructive periodontal disease (NIDPD) are described, their pathogenesis remains unknown. A unique NIDPD case was investigated by clinical, microbiological, immunological and genetic tools. The patient, a non-smoking dental surgeon with excessive oral hygiene practice, presented a generalized bone resorption and tooth mobility, but not gingival inflammation or occlusion problems. No hematological, immunological or endocrine alterations were found. No periodontopathogens (A. actinomycetemcomitans, P. gingivalis, F. nucleatum and T. denticola) or viruses (HCMV, EBV-1 and HSV-1) were detected, along with levels of IL-1β and TNF-α in GCF compatible with healthy tissues. Conversely ALP, ACP and RANKL GCF levels were similar to diseased periodontal sites. Genetic investigation demonstrated that the patient carried some SNPs, as well HLA-DR4 (*0404) and HLA-B27 alleles, considered risk factors for bone loss. Then, a less vigorous and diminished frequency of toothbrushing was recommended to the patient, resulting in the arrest of alveolar bone loss, associated with the return of ALP, ACP and RANKL in GCF to normality levels. In conclusion, the unusual case presented here is compatible with the previous description of NIDPD, and the results that a possible combination of excessive force and frequency of mechanical stimulation with a potentially bone loss prone genotype could result in the alveolar bone loss seen in NIDPD. PMID:22437688

  3. [A proposal for a new definition of excess mortality associated with influenza-epidemics and its estimation].

    PubMed

    Takahashi, M; Tango, T

    2001-05-01

    As methods for estimating excess mortality associated with influenza-epidemic, the Serfling's cyclical regression model and the Kawai and Fukutomi model with seasonal indices have been proposed. Excess mortality under the old definition (i.e., the number of deaths actually recorded in excess of the number expected on the basis of past seasonal experience) covers the random error for that portion of variation regarded as due to chance. In addition, it disregards the range of random variation of mortality with the season. In this paper, we propose a new definition of excess mortality associated with influenza-epidemics and a new estimation method, considering these questions with the Kawai and Fukutomi method. The new definition of excess mortality and a novel method for its estimation were generated as follows. Factors bringing about variation in mortality in months with influenza-epidemics may be divided into two groups: 1. Influenza itself, 2. others (practically random variation). The range of variation of mortality due to the latter (normal range) can be estimated from the range for months in the absence of influenza-epidemics. Excess mortality is defined as death over the normal range. A new definition of excess mortality associated with influenza-epidemics and an estimation method are proposed. The new method considers variation in mortality in months in the absence of influenza-epidemics. Consequently, it provides reasonable estimates of excess mortality by separating the portion of random variation. Further, it is a characteristic that the proposed estimate can be used as a criterion of statistical significance test.

  4. Development of a Consumable Inventory Management Strategy for the Supply Management Unit

    DTIC Science & Technology

    2007-12-01

    should be either returned to the supplier for partial credit or sent to disposal. This means that based 52 upon current and projected consumption ...economical to maintain based upon current and projected consumption rates. The magnitude of the feasible excess is driven by the base stock level prescribed...Days of Supply model to establish Requisitioning Objectives (RO) and Reorder Points (ROP), which are based upon historical usage, lead time, and supply

  5. The Semipalatinsk Nuclear Test Site: Through My Own Eyes

    DTIC Science & Technology

    2014-07-01

    valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 2. REPORT TYPE 3. DATES COVERED (From...Accordingly, this document is translated essentially verbatim, with only minor edits to clarify dated material, etc. Both the medical data he collected...There are three points on the Earth which have been poisoned by excessive ionizing radiation. The first is Hiroshima and Nagasaki, where the

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Paul, I.R.

    A pilot study in two states led to the establishment of the Dental Exposure Normalization Technique (DENT) program. This, in brief, is an exposure reduction and quality assurance program for radiological health agencies. The health agency sends X-ray exposure cards to dental X-ray facilities. These are exposed by the dentist and returned for analysis. Facilities which show excessive exposure are then visited to demonstrate the changes in exposure and processing necessary to produce diagnostic quality radiographs with minimum patient exposure.

  7. Maternity Leave: Tips for Returning to Work

    MedlinePlus

    ... set yourself up for a successful return to work: Find dependable child care. Consider local child care providers and facilities or make other arrangements. Look for a safe, stimulating environment and qualified caregivers. Ask your baby's doctor, friends, ...

  8. Seasonal and Non-Seasonal Generalized Pareto Distribution to Estimate Extreme Significant Wave Height in The Banda Sea

    NASA Astrophysics Data System (ADS)

    Nursamsiah; Nugroho Sugianto, Denny; Suprijanto, Jusup; Munasik; Yulianto, Bambang

    2018-02-01

    The information of extreme wave height return level was required for maritime planning and management. The recommendation methods in analyzing extreme wave were better distributed by Generalized Pareto Distribution (GPD). Seasonal variation was often considered in the extreme wave model. This research aims to identify the best model of GPD by considering a seasonal variation of the extreme wave. By using percentile 95 % as the threshold of extreme significant wave height, the seasonal GPD and non-seasonal GPD fitted. The Kolmogorov-Smirnov test was applied to identify the goodness of fit of the GPD model. The return value from seasonal and non-seasonal GPD was compared with the definition of return value as criteria. The Kolmogorov-Smirnov test result shows that GPD fits data very well both seasonal and non-seasonal model. The seasonal return value gives better information about the wave height characteristics.

  9. MOI to TEI : a Mars Sample Return strategy

    NASA Technical Reports Server (NTRS)

    Smith, Chad W.; Maddock, Robert W.

    2006-01-01

    This paper describes the issues and challenges related to the design of the rendezvous between the Earth Return Vehicle (ERV) and the Orbiting Sample (OS) for the Mars Sample Return (MSR) mission. In particular, attention will be focused on the strategy for 'optimizing' the intermediate segment of the rendezvous process, during which there are a great number of variables that must be considered and well understood.

  10. Comet nucleus and asteroid sample return missions

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Three Advanced Design Projects have been completed this academic year at Penn State. At the beginning of the fall semester the students were organized into eight groups and given their choice of either a comet nucleus or an asteroid sample return mission. Once a mission had been chosen, the students developed conceptual designs. These were evaluated at the end of the fall semester and combined into three separate mission plans, including a comet nucleus same return (CNSR), a single asteroid sample return (SASR), and a multiple asteroid sample return (MASR). To facilitate the work required for each mission, the class was reorganized in the spring semester by combining groups to form three mission teams. An integration team consisting of two members from each group was formed for each mission so that communication and information exchange would be easier among the groups. The types of projects designed by the students evolved from numerous discussions with Penn State faculty and mission planners at the Johnson Space Center Human/Robotic Spacecraft Office. Robotic sample return missions are widely considered valuable precursors to manned missions in that they can provide details about a site's environment and scientific value. For example, a sample return from an asteroid might reveal valuable resources that, once mined, could be utilized for propulsion. These missions are also more adaptable when considering the risk to humans visiting unknown and potentially dangerous locations, such as a comet nucleus.

  11. Potential Adverse Cardiovascular Effects From Excessive Endurance Exercise

    PubMed Central

    O'Keefe, James H.; Patil, Harshal R.; Lavie, Carl J.; Magalski, Anthony; Vogel, Robert A.; McCullough, Peter A.

    2012-01-01

    A routine of regular exercise is highly effective for prevention and treatment of many common chronic diseases and improves cardiovascular (CV) health and longevity. However, long-term excessive endurance exercise may induce pathologic structural remodeling of the heart and large arteries. Emerging data suggest that chronic training for and competing in extreme endurance events such as marathons, ultramarathons, ironman distance triathlons, and very long distance bicycle races, can cause transient acute volume overload of the atria and right ventricle, with transient reductions in right ventricular ejection fraction and elevations of cardiac biomarkers, all of which return to normal within 1 week. Over months to years of repetitive injury, this process, in some individuals, may lead to patchy myocardial fibrosis, particularly in the atria, interventricular septum, and right ventricle, creating a substrate for atrial and ventricular arrhythmias. Additionally, long-term excessive sustained exercise may be associated with coronary artery calcification, diastolic dysfunction, and large-artery wall stiffening. However, this concept is still hypothetical and there is some inconsistency in the reported findings. Furthermore, lifelong vigorous exercisers generally have low mortality rates and excellent functional capacity. Notwithstanding, the hypothesis that long-term excessive endurance exercise may induce adverse CV remodeling warrants further investigation to identify at-risk individuals and formulate physical fitness regimens for conferring optimal CV health and longevity. PMID:22677079

  12. Convective and radiative heating for vehicle return from the Moon and Mars

    NASA Technical Reports Server (NTRS)

    Greendyke, Robert B.; Gnoffo, Peter A.

    1995-01-01

    The aerothermal environment is examined for two vehicle forebodies near the peak heating points of lunar and martian return-to-earth trajectories at several nominal entry velocities. The first vehicle forebody is that of a 70 deg aerobrake for entry into earth orbit; the second, a capsule of Apollo configuration for direct entry into the earth's atmosphere. The configurations and trajectories are considered likely candidates for such missions. Two-temperature, thermochemical nonequilibrium models are used in the flow field analyses. In addition to Park's empirical model for dissociation under conditions of thermal nonequilibrium, the Gordiets kinetic model for the homonuclear dissociation of N2 and O2 is also considered. Temperature and emission profiles indicate nonequilibrium effects in a 2 to 5 cm post shock region. Substantial portions of the shock layer flow appear to be in equilibrium. The shock layer over an aerobrake for return from the moon exhibits the largest extent of nonequilibrium effects of all considered missions. Differences between the Gordiets and Parks kinetic model were generally very small for the lunar return aerobrake case, the greatest difference of 6.1 percent occurring in the radiative heating levels.

  13. Encephalopathy in acute liver failure resulting from acetaminophen intoxication: new observations with potential therapy.

    PubMed

    Brusilow, Saul W; Cooper, Arthur J L

    2011-11-01

    Hyperammonemia is a major contributing factor to the encephalopathy associated with liver disease. It is now generally accepted that hyperammonemia leads to toxic levels of glutamine in astrocytes. However, the mechanism by which excessive glutamine is toxic to astrocytes is controversial. Nevertheless, there is strong evidence that glutamine-induced osmotic swelling, especially in acute liver failure, is a contributing factor: the osmotic gliopathy theory. The object of the current communication is to present evidence for the osmotic gliopathy theory in a hyperammonemic patient who overdosed on acetaminophen. Case report. Johns Hopkins Hospital. A 22-yr-old woman who, 36 hrs before admission, ingested 15 g acetaminophen was admitted to the Johns Hopkins Hospital. She was treated with N-acetylcysteine. Physical examination was unremarkable; her mental status was within normal limits and remained so until approximately 72 hrs after ingestion when she became confused, irritable, and agitated. She was intubated, ventilated, and placed on lactulose. Shortly thereafter, she was noncommunicative, unresponsive to painful stimuli, and exhibited decerebrate posturing. A clinical diagnosis of cerebral edema and increased intracranial pressure was made. She improved very slowly until 180 hrs after ingestion when she moved all extremities. She woke up shortly thereafter. Despite the fact that hyperammonemia is a major contributing factor to the encephalopathy observed in acute liver failure, the patient's plasma ammonia peaked when she exhibited no obvious neurologic deficit. Thereafter, her plasma ammonia decreased precipitously in parallel with a worsening neurologic status. She was deeply encephalopathic during a period when her liver function and plasma ammonia had normalized. Plasma glutamine levels in this patient were high but began to normalize several hours after plasma ammonia had returned to normal. The patient only started to recover as her plasma glutamine began to return to normal. We suggest that the biochemical data are consistent with the osmotic gliopathy theory--high plasma ammonia leads to high plasma glutamine--an indicator of excess glutamine in astrocytes (the site of brain glutamine synthesis). This excess glutamine leads to osmotic stress in these cells. The lag in recovery of brain function presumably reflects time taken for the astrocyte glutamine concentration to return to normal. We hypothesize that an inhibitor of brain glutamine synthesis may be an effective treatment modality for acute liver failure.

  14. Encephalopathy in acute liver failure resulting from acetaminophen intoxication: New observations with potential therapy

    PubMed Central

    Brusilow, Saul W; Cooper, Arthur J.L.

    2011-01-01

    Objective Hyperammonemia is a major contributing factor to the encephalopathy associated with liver disease. It is now generally accepted that hyperammonemia leads to toxic levels of glutamine in astrocytes. However, the mechanism by which excessive glutamine is toxic to astrocytes is controversial. Nevertheless, there is strong evidence that glutamine-induced osmotic swelling, especially in acute liver failure (ALF), is a contributing factor – the osmotic gliopathy theory. The object of the current communication is to present evidence for the osmotic gliopathy theory in a hyperammonemic patient who overdosed on acetaminophen. Design Case report. Setting Johns Hopkins Hospital. Patient A 22-year old white female who, 36 hours prior to admission, ingested 15 grams of acetaminophen was admitted to the Johns Hopkins Hospital. Physical examination was unremarkable; her mental status was within normal limits and remained so until approximately 72 hours after ingestion when she became confused, irritable and agitated. Interventions She was intubated, ventilated and placed on lactulose. Shortly thereafter she was non-communicative, unresponsive to painful stimuli and exhibited decerebrate posturing. A clinical diagnosis of cerebral edema and increased intracranial pressure (ICP) was made. She improved very slowly until 180 hours after ingestion when she moved all extremities. She woke up shortly thereafter. Measurements and main results Despite the fact that hyperammonemia is a major contributing factor to the encephalopathy observed in ALF the patient’s plasma ammonia peaked when she exhibited no obvious neurological deficit. Thereafter, her plasma ammonia decreased precipitously in parallel with a worsening neurological status. She was deeply encephalopathic during a period when her liver function and plasma ammonia had normalized. Plasma glutamine levels in this patient were high, but began to normalize several hours after plasma ammonia had returned to normal. The patient only commenced to recover as her plasma glutamine began to return to normal. Conclusions We suggest that the biochemical data are consistent with the osmotic gliopathy theory – high plasma ammonia leads to high plasma glutamine – an indicator of excess glutamine in astrocytes (the site of brain glutamine synthesis). This excess glutamine leads to osmotic stress in these cells. The lag in recovery of brain function presumably reflects time taken for the astrocyte glutamine concentration to return to normal. We hypothesize that an inhibitor of brain glutamine synthesis may be an effective treatment modality for ALF. PMID:21705899

  15. Portfolios with fuzzy returns: Selection strategies based on semi-infinite programming

    NASA Astrophysics Data System (ADS)

    Vercher, Enriqueta

    2008-08-01

    This paper provides new models for portfolio selection in which the returns on securities are considered fuzzy numbers rather than random variables. The investor's problem is to find the portfolio that minimizes the risk of achieving a return that is not less than the return of a riskless asset. The corresponding optimal portfolio is derived using semi-infinite programming in a soft framework. The return on each asset and their membership functions are described using historical data. The investment risk is approximated by mean intervals which evaluate the downside risk for a given fuzzy portfolio. This approach is illustrated with a numerical example.

  16. An agent-based approach to financial stylized facts

    NASA Astrophysics Data System (ADS)

    Shimokawa, Tetsuya; Suzuki, Kyoko; Misawa, Tadanobu

    2007-06-01

    An important challenge of the financial theory in recent years is to construct more sophisticated models which have consistencies with as many financial stylized facts that cannot be explained by traditional models. Recently, psychological studies on decision making under uncertainty which originate in Kahneman and Tversky's research attract a lot of interest as key factors which figure out the financial stylized facts. These psychological results have been applied to the theory of investor's decision making and financial equilibrium modeling. This paper, following these behavioral financial studies, would like to propose an agent-based equilibrium model with prospect theoretical features of investors. Our goal is to point out a possibility that loss-averse feature of investors explains vast number of financial stylized facts and plays a crucial role in price formations of financial markets. Price process which is endogenously generated through our model has consistencies with, not only the equity premium puzzle and the volatility puzzle, but great kurtosis, asymmetry of return distribution, auto-correlation of return volatility, cross-correlation between return volatility and trading volume. Moreover, by using agent-based simulations, the paper also provides a rigorous explanation from the viewpoint of a lack of market liquidity to the size effect, which means that small-sized stocks enjoy excess returns compared to large-sized stocks.

  17. Application of steel slag coated with sodium hydroxide to enhance precipitation-coagulation for phosphorus removal.

    PubMed

    Park, Taejun; Ampunan, Vanvimol; Maeng, Sungkyu; Chung, Eunhyea

    2017-01-01

    Phosphorus removal has been studied for decades to reduce the environmental impact of phosphorus in natural waterbodies. Slag has been applied for the phosphorus removal by several mechanisms. In this study, sodium hydroxide coating was applied on the slag surface to enhance the efficiency of precipitation-coagulation process. In the batch test, it was found that the capacity of the slag to maintain high pH decreases with increasing its exposure time to the aqueous solution. In the column test, the coarse-grained coated slag showed higher phosphorus removal efficiency than the fine-grained uncoated slag. The coated slag maintained pH higher than uncoated slag and, accordingly, the removal efficiency of phosphorus was higher. Especially, when pH was less than 8, the removal efficiency decreased significantly. However, coated slag provided an excess amount of aluminum and sodium. Thus, a return process to reuse aluminum and sodium as a coagulant was introduced. The return process yields longer lifespan of slag with higher phosphorus removal and lower concentration of cations in the effluent. With the return process, the phosphorus removal efficiency was kept higher than 60% until 150 bed volumes; meanwhile, the efficiency without return process became lower than 60% at 25 bed volumes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Remote sensing and modeling of lightning caused long recovery events within the lower ionosphere using VLF/LF radio wave propagation

    NASA Astrophysics Data System (ADS)

    Schmitter, E. D.

    2014-11-01

    On the 4 November 2012 at 3:04:27 UT a strong lightning in the midst of the North Sea affected the propagation conditions of VLF/LF transmitter radio signals from NRK (Iceland, 37.5 kHz) and GBZ (UK, 19.58 kHz) received at 5246° N 8° E (NW Germany). The amplitude and phase dips show a recovery time of 6-12 min pointing to a LOng Recovery Early VLF (LORE) event. Clear assignment of the causative return stroke in space and time was possible with data from the WWLLN (Worldwide Lightning Location Network). Based on a return stroke current model the electric field is calculated and an excess electron density distribution which decays over time in the lower ionosphere is derived. Ionization, attachment and recombination processes are modeled in detail. Entering the electron density distribution in VLF/LF radio wave propagation calculations using the LWPC (Long Wavelength Propagation Capability) code allows to model the VLF/LF amplitude and phase behavior by adjusting the return stroke current moment. The results endorse and quantify the conception of lower ionosphere EMP heating by strong - but not necessarily extremely strong - return strokes of both polarities.

  19. Revisiting the returns-volume relationship: Time variation, alternative measures and the financial crisis

    NASA Astrophysics Data System (ADS)

    Cook, Steve; Watson, Duncan

    2017-03-01

    Following its introduction in the seminal study of Osborne (1959), a voluminous literature has emerged examining the returns-volume relationship for financial assets. The present paper revisits this relationship in an examination of the FTSE100 which extends the existing literature in two ways. First, alternative daily measures of the FTSE100 index are used to create differing returns and absolute returns series to employ in an examination of returns-volume causality. Second, rolling regression analysis is utilised to explore potential time variation in the returns-volume relationship. The findings obtained depict a hitherto unconsidered complexity in this relationship with the type of returns series considered and financial crisis found to be significant underlying factors. The implications of the newly derived results for both the understanding of the nature of the returns-volume relationship and the development of theories in connection to it are discussed.

  20. Modelling of capital asset pricing by considering the lagged effects

    NASA Astrophysics Data System (ADS)

    Sukono; Hidayat, Y.; Bon, A. Talib bin; Supian, S.

    2017-01-01

    In this paper the problem of modelling the Capital Asset Pricing Model (CAPM) with the effect of the lagged is discussed. It is assumed that asset returns are analysed influenced by the market return and the return of risk-free assets. To analyse the relationship between asset returns, the market return, and the return of risk-free assets, it is conducted by using a regression equation of CAPM, and regression equation of lagged distributed CAPM. Associated with the regression equation lagged CAPM distributed, this paper also developed a regression equation of Koyck transformation CAPM. Results of development show that the regression equation of Koyck transformation CAPM has advantages, namely simple as it only requires three parameters, compared with regression equation of lagged distributed CAPM.

  1. Analysis of the changes and difficulties arising from kidney transplantation: a qualitative study1

    PubMed Central

    de Brito, Daniela Cristina Sampaio; de Paula, Alessandra Moregola; Grincenkov, Fabiane Rossi dos Santos; Lucchetti, Giancarlo; Sanders-Pinheiro, Hélady

    2015-01-01

    OBJECTIVE: to identify the main gains and stressors perceived by the patient, one year subsequent to kidney transplantation. METHOD: a qualitative study, in which the data were obtained and analyzed through the Discourse of the Collective Subject and frequency counting, with the participation of 50 patients who had received kidney transplantation. RESULTS: the sample presented a mean age of 44±12.8 years old, and a predominance of males (62%). The principal positive changes provided by the transplant were: return to activities; freedom/independence; well-being and health; strengthening of the I; and closening of interpersonal relationships. The most-cited stressors were: fear; medication; excess of care/control; specific characteristics of the treatment; and failure to return to the social roles. CONCLUSION: kidney transplantation caused various positive changes in the patient's routine, with the return to activities of daily living being the most important gain, in the participants' opinion. In relation to the stressors, fear related to loss of the graft, and questions relating to the immunosuppressive medication were the main challenges to be faced following transplantation. PMID:26312633

  2. Single-Photon-Sensitive HgCdTe Avalanche Photodiode Detector

    NASA Technical Reports Server (NTRS)

    Huntington, Andrew

    2013-01-01

    The purpose of this program was to develop single-photon-sensitive short-wavelength infrared (SWIR) and mid-wavelength infrared (MWIR) avalanche photodiode (APD) receivers based on linear-mode HgCdTe APDs, for application by NASA in light detection and ranging (lidar) sensors. Linear-mode photon-counting APDs are desired for lidar because they have a shorter pixel dead time than Geiger APDs, and can detect sequential pulse returns from multiple objects that are closely spaced in range. Linear-mode APDs can also measure photon number, which Geiger APDs cannot, adding an extra dimension to lidar scene data for multi-photon returns. High-gain APDs with low multiplication noise are required for efficient linear-mode detection of single photons because of APD gain statistics -- a low-excess-noise APD will generate detectible current pulses from single photon input at a much higher rate of occurrence than will a noisy APD operated at the same average gain. MWIR and LWIR electron-avalanche HgCdTe APDs have been shown to operate in linear mode at high average avalanche gain (M > 1000) without excess multiplication noise (F = 1), and are therefore very good candidates for linear-mode photon counting. However, detectors fashioned from these narrow-bandgap alloys require aggressive cooling to control thermal dark current. Wider-bandgap SWIR HgCdTe APDs were investigated in this program as a strategy to reduce detector cooling requirements.

  3. 27 CFR 70.306 - Time for performance of acts other than payment of tax or filing of any return when the last day...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... acts other than payment of tax or filing of any return when the last day falls on Saturday, Sunday, or... performance of acts other than payment of tax or filing of any return when the last day falls on Saturday... falls on a Saturday, Sunday, or legal holiday, such act shall be considered performed timely if...

  4. 27 CFR 70.306 - Time for performance of acts other than payment of tax or filing of any return where last day...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... acts other than payment of tax or filing of any return where last day falls on Saturday, Sunday, or... performance of acts other than payment of tax or filing of any return where last day falls on Saturday, Sunday... falls on a Saturday, Sunday, or legal holiday, such act shall be considered performed timely if...

  5. 27 CFR 70.306 - Time for performance of acts other than payment of tax or filing of any return when the last day...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... acts other than payment of tax or filing of any return when the last day falls on Saturday, Sunday, or... performance of acts other than payment of tax or filing of any return when the last day falls on Saturday... falls on a Saturday, Sunday, or legal holiday, such act shall be considered performed timely if...

  6. 27 CFR 70.306 - Time for performance of acts other than payment of tax or filing of any return when the last day...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... acts other than payment of tax or filing of any return when the last day falls on Saturday, Sunday, or... performance of acts other than payment of tax or filing of any return when the last day falls on Saturday... falls on a Saturday, Sunday, or legal holiday, such act shall be considered performed timely if...

  7. 27 CFR 70.306 - Time for performance of acts other than payment of tax or filing of any return when the last day...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... acts other than payment of tax or filing of any return when the last day falls on Saturday, Sunday, or... performance of acts other than payment of tax or filing of any return when the last day falls on Saturday... falls on a Saturday, Sunday, or legal holiday, such act shall be considered performed timely if...

  8. Optimal investment horizons

    NASA Astrophysics Data System (ADS)

    Simonsen, I.; Jensen, M. H.; Johansen, A.

    2002-06-01

    In stochastic finance, one traditionally considers the return as a competitive measure of an asset, i.e., the profit generated by that asset after some fixed time span Δt, say one week or one year. This measures how well (or how bad) the asset performs over that given period of time. It has been established that the distribution of returns exhibits ``fat tails'' indicating that large returns occur more frequently than what is expected from standard Gaussian stochastic processes [1-3]. Instead of estimating this ``fat tail'' distribution of returns, we propose here an alternative approach, which is outlined by addressing the following question: What is the smallest time interval needed for an asset to cross a fixed return level of say 10%? For a particular asset, we refer to this time as the investment horizon and the corresponding distribution as the investment horizon distribution. This latter distribution complements that of returns and provides new and possibly crucial information for portfolio design and risk-management, as well as for pricing of more exotic options. By considering historical financial data, exemplified by the Dow Jones Industrial Average, we obtain a novel set of probability distributions for the investment horizons which can be used to estimate the optimal investment horizon for a stock or a future contract.

  9. A Dielectric-Filled Waveguide Antenna Element for 3D Imaging Radar in High Temperature and Excessive Dust Conditions

    PubMed Central

    Xu, Ding; Li, Zhiping; Chen, Xianzhong; Wang, Zhengpeng; Wu, Jianhua

    2016-01-01

    Three-dimensional information of the burden surface in high temperature and excessive dust industrial conditions has been previously hard to obtain. This paper presents a novel microstrip-fed dielectric-filled waveguide antenna element which is resistant to dust and high temperatures. A novel microstrip-to-dielectric-loaded waveguide transition was developed. A cylinder and cuboid composite structure was employed at the terminal of the antenna element, which improved the return loss performance and reduced the size. The proposed antenna element was easily integrated into a T-shape multiple-input multiple-output (MIMO) imaging radar system and tested in both the laboratory environment and real blast furnace environment. The measurement results show that the proposed antenna element works very well in industrial 3D imaging radar. PMID:27556469

  10. Elements of decisional dynamics: An agent-based approach applied to artificial financial market

    NASA Astrophysics Data System (ADS)

    Lucas, Iris; Cotsaftis, Michel; Bertelle, Cyrille

    2018-02-01

    This paper introduces an original mathematical description for describing agents' decision-making process in the case of problems affected by both individual and collective behaviors in systems characterized by nonlinear, path dependent, and self-organizing interactions. An application to artificial financial markets is proposed by designing a multi-agent system based on the proposed formalization. In this application, agents' decision-making process is based on fuzzy logic rules and the price dynamics is purely deterministic according to the basic matching rules of a central order book. Finally, while putting most parameters under evolutionary control, the computational agent-based system is able to replicate several stylized facts of financial time series (distributions of stock returns showing a heavy tail with positive excess kurtosis, absence of autocorrelations in stock returns, and volatility clustering phenomenon).

  11. Elements of decisional dynamics: An agent-based approach applied to artificial financial market.

    PubMed

    Lucas, Iris; Cotsaftis, Michel; Bertelle, Cyrille

    2018-02-01

    This paper introduces an original mathematical description for describing agents' decision-making process in the case of problems affected by both individual and collective behaviors in systems characterized by nonlinear, path dependent, and self-organizing interactions. An application to artificial financial markets is proposed by designing a multi-agent system based on the proposed formalization. In this application, agents' decision-making process is based on fuzzy logic rules and the price dynamics is purely deterministic according to the basic matching rules of a central order book. Finally, while putting most parameters under evolutionary control, the computational agent-based system is able to replicate several stylized facts of financial time series (distributions of stock returns showing a heavy tail with positive excess kurtosis, absence of autocorrelations in stock returns, and volatility clustering phenomenon).

  12. Luna 16 - Some Li, K, Rb, Sr, Ba, rare-earth, Zr, and Hf concentrations.

    NASA Technical Reports Server (NTRS)

    Philpotts, J. A.; Schnetzler, C. C.; Schuhmann, S.; Thomas , H. H.; Bottino, M. L.

    1972-01-01

    Concentrations of Li, K, Rb, Sr, Na, rare-earths, Zr and Hf have been determined for some Luna 16 core materials by mass-spectrometric isotope-dilution. Two regolith fines samples from different depths in the core, and four rock-chips, including both igneous rocks and breccias, have similar trace-element concentrations. The Luna 16 materials have general lunar trace-element characteristics but differ from other returned lunar samples in a manner that suggests the presence of excess feldspar. Unless the Luna 16 igneous rocks are fused soils, they appear to represent either partial plagioclase cumulates or the least differentiated igneous material yet returned from the moon. The similarity in trace-element concentrations of the igneous rocks and the fines would then suggest largely local derivation of the Luna 16 regolith.

  13. [Sense of Coherence Scale according to Antonovsky as a possible predictor for return to work for cardiac surgery intensive care patients].

    PubMed

    Benstoem, C; Wübker, R; Lüngen, M; Breuer, T; Marx, G; Autschbach, R; Goetzenich, A; Schnoering, H

    2018-05-14

    For cardiac surgery patients who were employed prior to surgery, the return to their professional life is of special importance. In addition to medical reasons, such as pre-existing conditions, the success of the operation or postoperative course and patient-intrinsic reasons, which can be assessed with the Sense of Coherence (SOC) scale by Antonovsky, may also play a role in the question of a possible return into working life. In this study 278 patients (invasive coronary artery bypass graft surgery and/or surgery on heart valves, age < 60 years, employed) were questioned postoperatively via post with the SOC questionnaire. The SOC questionnaire was used in addition to questions about return to work. The cohort was stratified according to the time of return to work. Subsequently, the point of maximum sensitivity and specificity was determined for the total SOC score and the prediction power was considered. Of the 278 patients, 61 questionnaires (22%) were considered as eligible and included in the analysis. Of these, 47 participants had returned to work after undergoing cardiac surgery and 14 participants had not. We observed significant differences in SOC values between both groups (146.07 ± 29.76 versus 124.29 ± 28.8, p = 0.020). Patients that returned to work within the first 6 months after surgery showed even higher SOC scores (148.56 ± 28.98, p = 0.034). Patients with an SOC score < 130 are at greater risk not to return to their professional life after cardiac surgery. The SOC is an easily obtainable score that reliably predicts the probability of return to work after cardiac surgery.

  14. Impact of Next Generation Sequencing on the Organization and Funding of Returning Research Results: Survey of Canadian Research Ethics Boards Members

    PubMed Central

    Godard, Beatrice

    2016-01-01

    Research Ethics Boards (REBs) are expected to evaluate protocols planning the use of Next Generation Sequencing technologies (NGS), assuring that any genomic finding will be properly managed. As Canadian REBs play a central role in the disclosure of such results, we deemed it important to examine the views and experience of REB members on the return of aggregated research results, individual research results (IRRs) and incidental findings (IFs) in current genomic research. With this intent, we carried out a web-based survey, which showed that 59.7% of respondents viewed the change from traditional sequencing to NGS as more than a technical substitution, and that 77% of respondents agreed on the importance of returning aggregated research results, the most compelling reasons being the recognition of participants’ contribution and increasing the awareness of scientific progress. As for IRRs specifically, 50% of respondents were in favour of conveying such information, even when they only indicated the probability that a condition may develop. Current regulations and risk to participants were considered equally important, and much more than financial costs, when considering the return of IRRs and IFs. Respondents indicated that the financial aspect of offering genetic counseling was the least important matter when assessing it as a requisite. Granting agencies were named as mainly responsible for funding, while the organizing and returning of IRRs and IFs belonged to researchers. However, views in these matters differ according to respondents’ experience. Our results draw attention to the need for improved guidance when considering the organizational and financial aspects of returning genetic research results, so as to better fulfill the ethical and moral principles that are to guide such undertakings. PMID:27167380

  15. Predictability of Bristol Bay, Alaska, sockeye salmon returns one to four years in the future

    USGS Publications Warehouse

    Adkison, Milo D.; Peterson, R.M.

    2000-01-01

    Historically, forecast error for returns of sockeye salmon Oncorhynchus nerka to Bristol Bay, Alaska, has been large. Using cross-validation forecast error as our criterion, we selected forecast models for each of the nine principal Bristol Bay drainages. Competing forecast models included stock-recruitment relationships, environmental variables, prior returns of siblings, or combinations of these predictors. For most stocks, we found prior returns of siblings to be the best single predictor of returns; however, forecast accuracy was low even when multiple predictors were considered. For a typical drainage, an 80% confidence interval ranged from one half to double the point forecast. These confidence intervals appeared to be appropriately wide.

  16. Returning findings within longitudinal cohort studies: the 1958 birth cohort as an exemplar.

    PubMed

    Wallace, Susan E; Walker, Neil M; Elliott, Jane

    2014-01-01

    Population-based, prospective longitudinal cohort studies are considering the issues surrounding returning findings to individuals as a result of genomic and other medical research studies. While guidance is being developed for clinical settings, the process is less clear for those conducting longitudinal research. This paper discusses work conducted on behalf of The UK Cohort and Longitudinal Study Enhancement Resource programme (CLOSER) to examine consent requirements, process considerations and specific examples of potential findings in the context of the 1958 British Birth cohort. Beyond deciding which findings to return, there are questions of whether re-consent is needed and the possible impact on the study, how the feedback process will be managed, and what resources are needed to support that process. Recommendations are made for actions a cohort study should consider taking when making vital decisions regarding returning findings. Any decisions need to be context-specific, arrived at transparently, communicated clearly, and in the best interests of both the participants and the study.

  17. Religious Zionism and Israeli Settlement Policy

    DTIC Science & Technology

    2014-06-01

    Kook translate directly into the doctrines and actions of Gush Emunim.270 These ideas include Israel’s God -given ownership of their ancient homeland...founded by Theodore Herzl in 1897, and the traditional rabbinic teaching that rejects human efforts to secure a return to the ancient land of... ancient land of Israel. Religious Zionism is founded on the belief that Jews have an obligation to return to Israel; such a return is considered a

  18. Revisiting the investor sentiment-stock returns relationship: A multi-scale perspective using wavelets

    NASA Astrophysics Data System (ADS)

    Lao, Jiashun; Nie, He; Jiang, Yonghong

    2018-06-01

    This paper employs SBW proposed by Baker and Wurgler (2006) to investigate the nonlinear asymmetric Granger causality between investor sentiment and stock returns for US economy while considering different time-scales. The wavelet method is utilized to decompose time series of investor sentiment and stock returns at different time-scales to focus on the local analysis of different time horizons of investors. The linear and nonlinear asymmetric Granger methods are employed to examine the Granger causal relationship on similar time-scales. We find evidence of strong bilateral linear and nonlinear asymmetric Granger causality between longer-term investor sentiment and stock returns. Furthermore, we observe the positive nonlinear causal relationship from stock returns to investor sentiment and the negative nonlinear causal relationship from investor sentiment to stock returns.

  19. The family and alcohol: effects of excessive drinking and conceptualizations of spouses over recent decades.

    PubMed

    Hurcom, C; Copello, A; Orford, J

    2000-03-01

    There is much debate in the addiction literature about the extent to which excessive drinking affects nondrinking family members. The issue is considered in this review by examining and evaluating research relating to the effects of drinking on children, family systems, and partners of drinkers. The latter group have, historically, been blamed and apologized for their partner's drinking, although more recent theories have adopted a stress and coping paradigm, thus normalizing individuals and their behaviors. Conceptualizations of spouses over the last five decades are described and evaluated in the second part of the review. Finally, the review considers the impact of the recent stress and coping paradigm on clinical interventions for excessive drinkers and their families, and suggestions are made for future research.

  20. Replica Analysis for Portfolio Optimization with Single-Factor Model

    NASA Astrophysics Data System (ADS)

    Shinzato, Takashi

    2017-06-01

    In this paper, we use replica analysis to investigate the influence of correlation among the return rates of assets on the solution of the portfolio optimization problem. We consider the behavior of an optimal solution for the case where the return rate is described with a single-factor model and compare the findings obtained from our proposed methods with correlated return rates with those obtained with independent return rates. We then analytically assess the increase in the investment risk when correlation is included. Furthermore, we also compare our approach with analytical procedures for minimizing the investment risk from operations research.

  1. Space tug aerobraking study. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    Corso, C. J.; Eyer, C. L.

    1972-01-01

    The feasibility and practicality of employing an aerobraking trajectory for return of the reusable space tug from geosynchronous orbit was investigated. The aerobraking return trajectory modes employ transfer ellipses from high orbits which have low perigee altitudes wherein the earth's sensible atmosphere provides drag to reduce the tug return delta velocity requirements and thus decrease the required return trip propulsive energy. Aerodynamics, aerothermodynamics, trajectories, guidance and control, configuration concepts, materials, weights and performance were considered. Sensitivities to trajectory uncertainties, atmospheric anomalies and reentry environments were determined. New technology requirements and future studies required to further enhance the aerobraking potential were identified.

  2. KSC01pp0732

    NASA Image and Video Library

    2001-03-29

    In the Space Station Processing Facility, workers line up containers removed from the Multi-Purpose Logistics Module Leonardo. The containers have returned from the International Space Station on mission STS-102. . The MPLM brought back to KSC nearly a ton of trash and excess equipment from the Space Station. Leonardo is one of three MPLMs built by the Italian Space Agency to serve as “cargo vans” to the Station, carrying supplies and equipment. In the SSPF, Leonardo will be prepared for a future mission

  3. KSC01pp0729

    NASA Image and Video Library

    2001-03-29

    KENNEDY SPACE CENTER, FLA. -- Inside the Multi-Purpose Logistics Module Leonardo, which is in the Space Station Processing Facility, workers begin removing the containers returned from the International Space Station on mission STS-102. The MPLM brought back to KSC nearly a ton of trash and excess equipment from the Space Station. Leonardo is one of three MPLMs built by the Italian Space Agency to serve as “cargo vans” to the Station, carrying supplies and equipment. In the SSPF, Leonardo will be prepared for a future mission

  4. KSC01pp0731

    NASA Image and Video Library

    2001-03-29

    KENNEDY SPACE CENTER, FLA. -- Inside the Multi-Purpose Logistics Module Leonardo, which is in the Space Station Processing Facility, workers remove one of the containers returned from the International Space Station on mission STS-102. The MPLM brought back to KSC nearly a ton of trash and excess equipment from the Space Station. Leonardo is one of three MPLMs built by the Italian Space Agency to serve as “cargo vans” to the Station, carrying supplies and equipment. In the SSPF, Leonardo will be prepared for a future mission

  5. KSC01pp0730

    NASA Image and Video Library

    2001-03-29

    KENNEDY SPACE CENTER, FLA. -- Inside the Multi-Purpose Logistics Module Leonardo, which is in the Space Station Processing Facility, workers look over containers returned from the International Space Station on mission STS-102. The MPLM brought back to KSC nearly a ton of trash and excess equipment from the Space Station. Leonardo is one of three MPLMs built by the Italian Space Agency to serve as “cargo vans” to the Station, carrying supplies and equipment. In the SSPF, Leonardo will be prepared for a future mission

  6. Estimating and modelling cure in population-based cancer studies within the framework of flexible parametric survival models.

    PubMed

    Andersson, Therese M L; Dickman, Paul W; Eloranta, Sandra; Lambert, Paul C

    2011-06-22

    When the mortality among a cancer patient group returns to the same level as in the general population, that is, the patients no longer experience excess mortality, the patients still alive are considered "statistically cured". Cure models can be used to estimate the cure proportion as well as the survival function of the "uncured". One limitation of parametric cure models is that the functional form of the survival of the "uncured" has to be specified. It can sometimes be hard to find a survival function flexible enough to fit the observed data, for example, when there is high excess hazard within a few months from diagnosis, which is common among older age groups. This has led to the exclusion of older age groups in population-based cancer studies using cure models. Here we have extended the flexible parametric survival model to incorporate cure as a special case to estimate the cure proportion and the survival of the "uncured". Flexible parametric survival models use splines to model the underlying hazard function, and therefore no parametric distribution has to be specified. We have compared the fit from standard cure models to our flexible cure model, using data on colon cancer patients in Finland. This new method gives similar results to a standard cure model, when it is reliable, and better fit when the standard cure model gives biased estimates. Cure models within the framework of flexible parametric models enables cure modelling when standard models give biased estimates. These flexible cure models enable inclusion of older age groups and can give stage-specific estimates, which is not always possible from parametric cure models. © 2011 Andersson et al; licensee BioMed Central Ltd.

  7. Estimating and modelling cure in population-based cancer studies within the framework of flexible parametric survival models

    PubMed Central

    2011-01-01

    Background When the mortality among a cancer patient group returns to the same level as in the general population, that is, the patients no longer experience excess mortality, the patients still alive are considered "statistically cured". Cure models can be used to estimate the cure proportion as well as the survival function of the "uncured". One limitation of parametric cure models is that the functional form of the survival of the "uncured" has to be specified. It can sometimes be hard to find a survival function flexible enough to fit the observed data, for example, when there is high excess hazard within a few months from diagnosis, which is common among older age groups. This has led to the exclusion of older age groups in population-based cancer studies using cure models. Methods Here we have extended the flexible parametric survival model to incorporate cure as a special case to estimate the cure proportion and the survival of the "uncured". Flexible parametric survival models use splines to model the underlying hazard function, and therefore no parametric distribution has to be specified. Results We have compared the fit from standard cure models to our flexible cure model, using data on colon cancer patients in Finland. This new method gives similar results to a standard cure model, when it is reliable, and better fit when the standard cure model gives biased estimates. Conclusions Cure models within the framework of flexible parametric models enables cure modelling when standard models give biased estimates. These flexible cure models enable inclusion of older age groups and can give stage-specific estimates, which is not always possible from parametric cure models. PMID:21696598

  8. Post-mating inflammatory responses of the uterus.

    PubMed

    Katila, T

    2012-08-01

    This review attempts to summarize the current knowledge on uterine inflammatory response after mating in horses, pigs and cattle. Post-mating endometritis has been extensively studied in horses as it has been considered to cause infertility. The inflammation is known to occur also in cattle, but it has not been investigated to a similar extent. There are a number of publications about mechanisms of post-mating uterine inflammation in pigs, which seem to resemble those in horses. The major focus of this review is the horse, but relevant literature is presented also on swine and cattle. Spermatozoa, seminal plasma and semen extenders play roles in the induction of inflammation. In addition, sperm numbers, concentration and viability, as well as the site of semen deposition may modulate the inflammatory response. Cytokines, polymorphonuclear leucocytes (PMN) and mononuclear cells represent the uterine inflammatory response to mating. Inflammation is the first line of defence against invasion and eliminates excess spermatozoa and bacteria. Semen deposition elicits a massive PMN invasion, followed by phagocytosis of sperm aided by the formation of neutrophil extracellular traps. Exposure of the female genital tract to semen is important also for endometrial receptivity and pre-implantation embryo development. Seminal plasma (SP) and inflammation elicit transient immune tolerance to antigens present in semen. SP contains immune-regulatory molecules that activate and control immune responses to antigens by stimulating expression of cytokines and growth factors and by initiating tissue remodelling. SP also regulates ovarian function. Effective elimination of excess sperm and inflammatory by-products and subsequent rapid return of the endometrium to the normal state is a prerequisite for pregnancy. Uterine backflow, driven by myometrial contractions and requiring a patent cervix, is an important physical tool in uterine drainage. © 2012 Blackwell Verlag GmbH.

  9. Natural chlorine and fluorine in the atmosphere, water and precipitation

    NASA Technical Reports Server (NTRS)

    Friend, James P.

    1990-01-01

    The geochemical cycles of chlorine and fluorine are surveyed and summarized as framework for the understanding of the global natural abundances of these species in the atmosphere, water, and precipitation. In the cycles the fluxes into and out of the atmosphere can be balanced within the limits of our knowledge of the natural sources and sinks. Sea salt from the ocean surfaces represent the predominant portion of the source of chlorine. It is also an important source of atmospheric fluorine, but volcanoes are likely to be more important fluorine sources. Dry deposition of sea salt returns about 85 percent of the salt released there. Precipitation removes the remainder. Most of the sea salt materials are considered to be cyclic, moving through sea spray over the oceans and either directly back to the oceans or deposited dry and in precipitation on land, whence it runs off into rivers and streams and returns to the oceans. Most of the natural chlorine in the atmosphere is in the form of particulate chloride ion with lesser amounts as gaseous inorganic chloride and methyl chloride vapor. Fluorine is emitted from volcanoes primarily as HF. It is possible that HF may be released directly form the ocean surface but this has not been confirmed by observation. HCl and most likely HF gases are released into the atmosphere by sea salt aerosols. The mechanism for the release is likely to be the provision of protons from the so-called excess sulfate and HNO3. Sea salt aerosol contains fluorine as F(-), MgF(+), CaF(+), and NaF. The concentrations of the various species of chlorine and fluorine that characterize primarily natural, unpolluted atmospheres are summarized in tables and are discussed in relation to their fluxes through the geochemical cycle.

  10. Resource engineering and economic studies for direct application of geothermal energy. Draft final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1981-12-01

    The feasibility of utilizing geothermal energy at a selected plant in New York State was studied. Existing oil and gas records suggests that geothermal fluid is available in the target area and based on this potential. Friendship Dairies, Inc., Friendship, NY, was selected as a potential user of geothermal energy. Currently natural gas and electricity are used as its primary energy sources. Six geothermal system configurations were analyzed based on replacement of gas or oil-fired systems for producing process heat. Each system was evaluated in terms of Internal Rate of Return on Investment (IRR), and simple payback. Six system configurationsmore » and two replaced fuels, representative of a range of situations found in the state, are analyzed. Based on the potential geothermal reserves at Friendship, each of the six system configurations are shown to be economically viable, compared to continued gas or oil-firing. The Computed IRR's are all far in excess of projected average interest rates for long term borrowings: approximately 15% for guarantee backed loans or as high as 20% for conventional financing. IRR is computed based on the total investment (equity plus debt) and cash flows before financing costs, i.e., before interest expense, but after the tax benefit of the interest deduction. The base case application for the Friendship analysis is case B/20 yr-gas which produces an IRR of 28.5% and payback of 3.4 years. Even better returns could be realized in the cases of oil-avoidance and where greater use of geothermal energy can be made as shown in the other cases considered.« less

  11. Return-on-Investment (ROI) Analyses of an Inpatient Lay Health Worker Model on 30-Day Readmission Rates in a Rural Community Hospital.

    PubMed

    Cardarelli, Roberto; Bausch, Gregory; Murdock, Joan; Chyatte, Michelle Renee

    2017-07-07

    The purpose of the study was to assess the return-on-investment (ROI) of an inpatient lay health worker (LHW) model in a rural Appalachian community hospital impacting 30-day readmission rates. The Bridges to Home (BTH) study completed an evaluation in 2015 of an inpatient LHW model in a rural Kentucky hospital that demonstrated a reduction in 30-day readmission rates by 47.7% compared to a baseline period. Using the hospital's utilization and financial data, a validated ROI calculator specific to care transition programs was used to assess the ROI of the BTH model comparing 3 types of payment models including Diagnosis Related Group (DRG)-only payments, pay-for-performance (P4P) contracts, and accountable care organizations (ACOs). The BTH program had a -$0.67 ROI if the hospital had only a DRG-based payment model. If the hospital had P4P contracts with payers and 0.1% of its annual operating revenue was at risk, the ROI increased to $7.03 for every $1 spent on the BTH program. However, if the hospital was an ACO as was the case for this study's community hospital, the ROI significantly increased to $38.48 for every $1 spent on the BTH program. The BTH model showed a viable ROI to be considered by community hospitals that are part of an ACO or P4P program. A LHW care transition model may be a cost-effective alternative for impacting excess 30-day readmissions and avoiding associated penalties for hospital systems with a value-based payment model. © 2017 National Rural Health Association.

  12. Evaluation of gonorrhea test of cure at 1 week in a Los Angeles community-based clinic serving men who have sex with men.

    PubMed

    Beymer, Matthew R; Llata, Eloisa; Stirland, Ali M; Weinstock, Hillard S; Wigen, Christine L; Guerry, Sarah L; Mejia, Everardo; Bolan, Robert K

    2014-10-01

    Because of the decreasing susceptibility of Neisseria gonorrhoeae to cephalosporin therapy, the Centers for Disease Control and Prevention recommends test of cure (TOC) 1 week after gonorrhea (GC) treatment if therapies other than ceftriaxone are used. In addition, the Centers for Disease Control and Prevention asks clinicians, particularly those caring for men who have sex with men (MSM) on the west coast, to consider retesting all MSM at 1 week. However, it is unclear if this is acceptable to providers and patients or if nucleic acid amplification tests (NAATs) are useful for TOC at 7 days. Between January and July 2012, MSM with GC were advised to return 1 week after treatment for TOC using NAAT. A multivariate logistic regression model was used to determine demographic and behavioral differences between MSM who returned for follow-up and MSM who did not. Of 737 men with GC, 194 (26.3%) returned between 3 and 21 days of treatment. Individuals who returned were more likely to have no GC history (P = 0.0001) and to report no initial symptoms (P = 0.02) when compared with individuals who did not return for TOC. Of those who returned, 0% of urethral samples, 7.4% of rectal samples, and 5.3% of pharyngeal samples were NAAT positive at TOC. Although TOC may be an important strategy in reducing complications and the spread of GC, low return rates may make implementation challenging. If implemented, extra efforts should be considered to enhance return rates among individuals with a history of GC. If TOCs are recommended at 1 week and NAATs are used, the interpretation of positive results, particularly those from extragenital sites, may be difficult.

  13. A threshold model of investor psychology

    NASA Astrophysics Data System (ADS)

    Cross, Rod; Grinfeld, Michael; Lamba, Harbir; Seaman, Tim

    2005-08-01

    We introduce a class of agent-based market models founded upon simple descriptions of investor psychology. Agents are subject to various psychological tensions induced by market conditions and endowed with a minimal ‘personality’. This personality consists of a threshold level for each of the tensions being modeled, and the agent reacts whenever a tension threshold is reached. This paper considers an elementary model including just two such tensions. The first is ‘cowardice’, which is the stress caused by remaining in a minority position with respect to overall market sentiment and leads to herding-type behavior. The second is ‘inaction’, which is the increasing desire to act or re-evaluate one's investment position. There is no inductive learning by agents and they are only coupled via the global market price and overall market sentiment. Even incorporating just these two psychological tensions, important stylized facts of real market data, including fat-tails, excess kurtosis, uncorrelated price returns and clustered volatility over the timescale of a few days are reproduced. By then introducing an additional parameter that amplifies the effect of externally generated market noise during times of extreme market sentiment, long-time volatility correlations can also be recovered.

  14. Consider long-term care as service alternative.

    PubMed

    Loria, L S

    1987-04-01

    The increasing demand for elderly care services, pressures on inpatient average length of stay and payment levels, and potential financial rewards from providing additional services, makes long-term care look attractive to hospitals. Long-term care, however, is not for every hospital. Before deciding to establish long-term care services, management should examine how the service fits within the hospital's strategic plan. The action plan below provides guidance in evaluating a decision to use hospital facilities for long-term care. Examine how long-term care services fit within the hospital's strategic plan. Study area demographics and competitors to assess the need and supply of long-term care services. Survey the medical staff, consumers and payers to determine attitudes, perceptions and interests regarding long-term care services. Develop a facility plan that identifies areas of excess capacity that can be most easily converted into long-term care with minimal effects on hospital operations. Prepare a financial feasibility analysis of the contribution margin and return on investment attributable to long-term care services. Include an impact analysis on hospital operations. Establish a management task force to develop a detailed implementation plan including assigned individual responsibilities and related timetable. Develop an effective marketing plan designed to generate increased patient market share.

  15. Thermal management of high power space based systems

    NASA Technical Reports Server (NTRS)

    Hwangbo, H.; Mcever, W. S.

    1985-01-01

    Conventional techniques of using a portion of the spacecraft skin for radiation of waste heat will be inadequate for high powered payloads (50 to 100 kWe) due to the lack of sufficient area. A Shuttle type system using a pumped single phase fluid loop could be scaled up to higher power but this type of system would require excessive pump power and weight. A pumped two-phase heat transfer loop has a much lower pumping requirement due to the higher latent heat of vaporization of the fluid in comparison to the sensible heat it can absorb through a temperature change. Concepts for an evaporator and a condenser for a pumped two-phase system are described. The condenser uses capillary grooves and a separate pumped condensate return line to achieve high heat transfer coefficients and stable operation due to the separation of the vapor and liquid flows. The cold plate evaporator uses wicks to contain the liquid and transport it to the heated surface. It can also function as a condenser for warming components. Control concepts for the cold plate are discussed. Concepts for deployment or erection of large space radiators are also considered.

  16. The dynamic conditional relationship between stock market returns and implied volatility

    NASA Astrophysics Data System (ADS)

    Park, Sung Y.; Ryu, Doojin; Song, Jeongseok

    2017-09-01

    Using the dynamic conditional correlation multivariate generalized autoregressive conditional heteroskedasticity (DCC-MGARCH) model, we empirically examine the dynamic relationship between stock market returns (KOSPI200 returns) and implied volatility (VKOSPI), as well as their statistical mechanics, in the Korean market, a representative and leading emerging market. We consider four macroeconomic variables (exchange rates, risk-free rates, term spreads, and credit spreads) as potential determinants of the dynamic conditional correlation between returns and volatility. Of these macroeconomic variables, the change in exchange rates has a significant impact on the dynamic correlation between KOSPI200 returns and the VKOSPI, especially during the recent financial crisis. We also find that the risk-free rate has a marginal effect on this dynamic conditional relationship.

  17. Interpreting 750 GeV diphoton excess in plain NMSSM

    DOE PAGES

    Badziak, Marcin; Olechowski, Marek; Pokorski, Stefan; ...

    2016-06-29

    NMSSM has enough ingredients to explain the diphoton excess at 750 GeV: singlet-like (pseudo) scalar (a) s and higgsinos as heavy vector-like fermions. We consider the production of the 750 GeV singlet-like pseudo scalar a from a decay of the doublet-like pseudo scalar A, and the subsequent decay of a into two photons via higgsino loop. We demonstrate that this cascade decay of the NMSSM Higgs bosons can explain the diphoton excess at 750 GeV.

  18. [Worrying behaviour in pre-school children aged three to seven years: a factor analysis of the results of a questionnaire].

    PubMed

    Pilecki, Maciej Wojciech; Kowal, Małgorzata; Woronkowicz, Agnieszka; Sobiecki, Jan; Kryst, Łukasz; Kamińska-Reyman, Jadwiga

    2014-01-01

    The aims of the study were: 1) the assessment of the interaction between the factors specified for behavioural problems observed in pre-school children based on a factor analysis and 2) the assessment of the relationship the specified factors have with the age and gender of the study group. A factor analysis based on a Principal Component Analysis of the main results of a Disturbing Behaviour Questionnaire (DBQ) completed by pre-school teachers, which includes categories of behaviour observed among pre-school age children that provoke the greatest concern among parents, guardians and educators. Nine-hundred and sixty-one children aged from 2.7 to 7.9 years (mean: 5.4; SD 1.13) from randomly chosen pre-schools in all districts of Krak6w. Based on a screen plot, as well as on a substantive analysis of the results, a decision was taken to employ a four-factor analysis (Lagging behind, Excessive behaviour, Eating-avoidance and Overeating) explaining 68% of the common factor variance. A very high Cronbach's alpha value was returned for the reliability of the individual scales. The conducted analysis of the relationship of the scales with age and gender indicated a greater intensity of disturbing behaviour in boys for the Lagging behind factor, the Excessive behaviour factor and the overall scale for the Disturbing Behaviour Questionnaire (DBQ). These were the scales, along with the Eating-avoidance scale, that were found to be related to age. A greater intensity of disturbing behaviour was found to occur in the younger children. The relationship between the Overeating and Excessive behaviour scales that was found among girls but not among boys indicated that--even at such a young age--the characteristics associated with eating in the context of gender were already present. The authors consider that the coherence of the results obtained and their consistency with other studies ofpre-school age children provide a sound platform for further analyses using the questionnaire described above.

  19. DSOD Procedures for Seismic Hazard Analysis

    NASA Astrophysics Data System (ADS)

    Howard, J. K.; Fraser, W. A.

    2005-12-01

    DSOD, which has jurisdiction over more than 1200 dams in California, routinely evaluates their dynamic stability using seismic shaking input ranging from simple pseudostatic coefficients to spectrally matched earthquake time histories. Our seismic hazard assessments assume maximum earthquake scenarios of nearest active and conditionally active seismic sources. Multiple earthquake scenarios may be evaluated depending on sensitivity of the design analysis (e.g., to certain spectral amplitudes, duration of shaking). Active sources are defined as those with evidence of movement within the last 35,000 years. Conditionally active sources are those with reasonable expectation of activity, which are treated as active until demonstrated otherwise. The Division's Geology Branch develops seismic hazard estimates using spectral attenuation formulas applicable to California. The formulas were selected, in part, to achieve a site response model similar to the 2000 IBC's for rock, soft rock, and stiff soil sites. The level of dynamic loading used in the stability analysis (50th, 67th, or 84th percentile ground shaking estimates) is determined using a matrix that considers consequence of dam failure and fault slip rate. We account for near-source directivity amplification along such faults by adjusting target response spectra and developing appropriate design earthquakes for analysis of structures sensitive to long-period motion. Based on in-house studies, the orientation of the dam analysis section relative to the fault-normal direction is considered for strike-slip earthquakes, but directivity amplification is assumed in any orientation for dip-slip earthquakes. We do not have probabilistic standards, but we evaluate the probability of our ground shaking estimates using hazard curves constructed from the USGS Interactive De-Aggregation website. Typically, return periods for our design loads exceed 1000 years. Excessive return periods may warrant a lower design load. Minimum shaking levels are provided for sites far from active faulting. Our procedures and standards are presented at the DSOD website http://damsafety.water.ca.gov/. We review our methods and tools periodically under the guidance of our Consulting Board for Earthquake Analysis (and expect to make changes pending NGA completion), mindful that frequent procedural changes can interrupt design evaluations.

  20. Spatial variation in attributable risks.

    PubMed

    Congdon, Peter

    2015-01-01

    The attributable risk (AR) measures the contribution of a particular risk factor to a disease, and allows estimation of disease rates specific to that risk. While previous studies consider variability in ARs over demographic categories, this paper considers the extent of spatial variability in ARs estimated from multilevel data with confounders both at individual and geographic levels. A case study considers the AR for diabetes in relation to elevated BMI, and area rates for diabetes attributable to excess weight. Contextual adjustment includes known area variables, and unobserved spatially clustered influences, while spatial heterogeneity (effect modification) is considered in terms of varying effects of elevated BMI by neighbourhood deprivation category. The application is to patient register data in London, with clear evidence of spatial variation in ARs, and in small area diabetes rates attributable to excess weight. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Excess electrons in reduced rutile and anatase TiO2

    NASA Astrophysics Data System (ADS)

    Yin, Wen-Jin; Wen, Bo; Zhou, Chuanyao; Selloni, Annabella; Liu, Li-Min

    2018-05-01

    As a prototypical photocatalyst, TiO2 is a material of scientific and technological interest. In photocatalysis and other applications, TiO2 is often reduced, behaving as an n-type semiconductor with unique physico-chemical properties. In this review, we summarize recent advances in the understanding of the fundamental properties and applications of excess electrons in reduced, undoped TiO2. We discuss the characteristics of excess electrons in the bulk and at the surface of rutile and anatase TiO2 focusing on their localization, spatial distribution, energy levels, and dynamical properties. We examine specific features of the electronic states for photoexcited TiO2, for intrinsic oxygen vacancy and Ti interstitial defects, and for surface hydroxyls. We discuss similarities and differences in the behaviors of excess electrons in the rutile and anatase phases. Finally, we consider the effect of excess electrons on the reactivity, focusing on the interaction between excess electrons and adsorbates.

  2. Personalized Health Planning With Integrative Health Coaching to Reduce Obesity Risk Among Women Gaining Excess Weight During Pregnancy

    PubMed Central

    Yang, Nancy Y.; Wroth, Shelley; Parham, Catherine; Strait, Melva

    2013-01-01

    Health coaching is an emerging behavioral intervention to improve outcomes in chronic disease management and prevention; however, no studies have investigated its utility in postpartum women who have gained excess weight during pregnancy. A 32-year-old primigravida woman who was overweight at conception and gained 23 lbs more than Institute of Medicine recommendations for her pre-pregnancy body mass index participated in a 6-month personalized health planning with integrative health coaching (PHPIHC) intervention. The intervention included a baseline health risk assessment review with a healthcare provider and eight biweekly, 30-minute telephonic health coaching sessions. The participant demonstrated improvement in physical activity, energy expenditure, knowledge, and confidence to engage in healthpromoting behaviors. Although the participant did not reach the target weight by completion of the health coaching sessions, follow up 8 months later indicated she achieved the target goal (within 5% of prepregnancy weight). This case report suggests that PHP-IHC can support postpartum women in returning to pre-pregnancy weight after gaining excess gestational weight. Future research and clinical trials are needed to determine the best timing, length, and medium (online, in-person, telephonic) of PHP-IHC for postpartum women. PMID:24278848

  3. Identification of dengue type 2 virus in febrile travellers returning from Burkina Faso to France, related to an ongoing outbreak, October to November 2016.

    PubMed

    Eldin, Carole; Gautret, Philippe; Nougairede, Antoine; Sentis, Mélanie; Ninove, Laetitia; Saidani, Nadia; Million, Matthieu; Brouqui, Philippe; Charrel, Remi; Parola, Philippe

    2016-12-15

    Dengue fever is rarely reported in travellers returning from Africa. We report two cases of dengue fever in travellers returning from Burkina Faso to France. One of them presented a severe dengue fever with ALT > 1,000 IU/L and pericarditis. Serotype 2 was identified. The cases reflect a large ongoing outbreak with over 1,000 reported cases between August and November in the capital city. Clinicians should consider dengue fever in malaria-negative febrile travellers returning from Africa. This article is copyright of The Authors, 2016.

  4. Changes in the Perceived Risk of Climate Change: Evidence from Sudden Climatic Events

    NASA Astrophysics Data System (ADS)

    Anttila-Hughes, J. K.

    2009-12-01

    In the course of the past two decades the threat of anthropogenic climate change has moved from a scientific concern of relative obscurity to become one of the largest environmental and public goods problems in history. During this period public understanding of the risk of climate change has shifted from negligible to quite large. In this paper I propose a means of quantifying this change by examining how sudden events supporting the theory of anthropogenic climate change have affected carbon intensive companies' stock prices. Using CAPM event study methodology for companies in several carbon-intensive industries, I find strong evidence that markets have been reacting to changes in the scientific evidence for climate change for some time. Specifically, the change in magnitude of response over time seems to indicate that investors believed climate change was a potentially serious risk to corporate profits as early as the mid 1990s. Moreover, market reaction dependence on event type indicates that investors are differentiating between different advances in the scientific knowledge. Announcements by NASA GISS that the previous year was a “record hot year” for the globe are associated with negative excess returns, while news of ice shelf collapses are associated with strong positive excess returns. These results imply that investors are aware of how different aspects of climate change will affect carbon intensive companies, specifically in terms of the link between warming in general and polar ice cover.

  5. Variation of Time Domain Failure Probabilities of Jack-up with Wave Return Periods

    NASA Astrophysics Data System (ADS)

    Idris, Ahmad; Harahap, Indra S. H.; Ali, Montassir Osman Ahmed

    2018-04-01

    This study evaluated failure probabilities of jack up units on the framework of time dependent reliability analysis using uncertainty from different sea states representing different return period of the design wave. Surface elevation for each sea state was represented by Karhunen-Loeve expansion method using the eigenfunctions of prolate spheroidal wave functions in order to obtain the wave load. The stochastic wave load was propagated on a simplified jack up model developed in commercial software to obtain the structural response due to the wave loading. Analysis of the stochastic response to determine the failure probability in excessive deck displacement in the framework of time dependent reliability analysis was performed by developing Matlab codes in a personal computer. Results from the study indicated that the failure probability increases with increase in the severity of the sea state representing a longer return period. Although the results obtained are in agreement with the results of a study of similar jack up model using time independent method at higher values of maximum allowable deck displacement, it is in contrast at lower values of the criteria where the study reported that failure probability decreases with increase in the severity of the sea state.

  6. [Further reduction of nitrogen fertilizer application in paddy field under green manuring of Taihu Area, China].

    PubMed

    Zhao, Dong; Yan, Ting-mei; Qiao, Jun; Yang, Lin-zhang; Tang, Fang; Song, Yun-fei

    2015-06-01

    This study focused on the nitrogen loss via runoff, change of nitrogen in different forms in surface water in paddy field, and grain yield, through further reduction of nitrogen fertilizer application rate under green manuring without basal dressing. Results showed that with 150 kg · hm(-2) inorganic N fertilizer input after return of green manure to soil, no basal dressing could not only sharply reduce N concentration in surface water and decrease 17.2% of N loss, but also increase 2.8% of grain yield in comparison with basal dressing. It was a worthwhile farming method that inorganic nitrogen fertilizer was not used for basal dressing but for topdressing after return of green ma- nure to soil in Taihu Area. However, the grain yield would decrease if the rate of topdressing nitro- gen was excessively reduced or increased. After all, it was feasible to realize harmonization of grain yield and environmental benefits in Taihu Area, with 133 kg · hm(-2) inorganic N fertilizer input after return of green manure to soil as well as no application of basal dressing, which could greatly reduce N fertilizer input and N loss as well as ensure rice yield.

  7. Common Problems Experienced by First Year Alternatively Certified Teachers: A Qualitative Study

    ERIC Educational Resources Information Center

    Hung, Li-Ching; Smith, Cary Stacy

    2012-01-01

    The teacher shortage throughout the United States, especially in areas considered "at-risk," has reached an alarming level. Novice teachers often decide not to return after one year of service, with the number of teachers not returning doubling at five years. One possible means of overcoming these two problems is alternative…

  8. A study of system requirements for Phobos/Diemos missions. Volume 3: Phase 2 results, satellite sample return missions and satellite mobility concepts

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The scientific objectives were considered for a Phobos/Deimos mission. The payloads for a minimum useful instrument complement were developed. The rationale for a sample return mission is discussed, along with the scientific constraints and requirements for the acquisition of samples.

  9. The Returned Prisoner of War: Factors in Family Reintegration

    ERIC Educational Resources Information Center

    McCubin, Hamilton I.; And Others

    1975-01-01

    Longitudinal study on 48 families of returned prisoners of war to identify factors to explain degree of reintegration of returnee into his family system. Four sets of data were considered: (1) background characteristics of husband and wife; (2) indices of family preparedness; (3) returnees' prison experiences and their psychiatric status; (4)…

  10. The Returns to Apprenticeship Training

    ERIC Educational Resources Information Center

    McIntosh, Steven

    2005-01-01

    This paper uses recent data from the UK Labour Force Survey to estimate the wage gains that individuals make on average if they complete an apprenticeship programme. The results suggest gains of around 5-7% for men, but no benefit for women. Further analysis extends the results by considering the returns by age group, by qualification obtained, by…

  11. Influences on the Intention to Enter Higher Education: The Importance of Expected Returns

    ERIC Educational Resources Information Center

    Menon, Maria Eliophotou; Markadjis, Elias; Theodoropoulos, Nikolaos; Socratous, Michalis

    2017-01-01

    Research points to several determinants of the private demand for higher education, which include individual, social, economic, and institutional variables. Of these variables, economic factors are considered to be highly relevant, especially in the current financial crisis. The paper investigates the link between expected rates of return to…

  12. Population age structure and asset returns: an empirical investigation.

    PubMed

    Poterba, J M

    1998-10-01

    "This paper investigates the association between population age structure, particularly the share of the population in the 'prime saving years' 45-60, and the returns on stocks and bonds. The paper is motivated by the claim that the aging of the 'Baby Boom' cohort in the United States is a key factor in explaining the recent rise in asset values. It also addresses the associated claim that asset prices will decline when this large cohort reaches retirement age and begins to reduce its asset holdings. This paper begins by considering household age-asset accumulation profiles. Data from the Survey of Consumer Finances suggest that while cross-sectional age-wealth profiles peak for households in their early 60s, cohort data on the asset ownership of the same households show a much less pronounced peak.... The paper then considers the historical relationship between demographic structure and real returns on Treasury bills, long-term government bonds, and corporate stock. The results do not suggest any robust relationship between demographic structure and asset returns.... The paper concludes by discussing factors such as international capital flows and forward-looking behavior on the part of market participants that could weaken the relationship between age structure and asset returns in a single nation." excerpt

  13. Evaluation of trade-offs in costs and environmental impacts for returnable packaging implementation

    NASA Astrophysics Data System (ADS)

    Jarupan, Lerpong; Kamarthi, Sagar V.; Gupta, Surendra M.

    2004-02-01

    The main thrust of returnable packaging these days is to provide logistical services through transportation and distribution of products and be environmentally friendly. Returnable packaging and reverse logistics concepts have converged to mitigate the adverse effect of packaging materials entering the solid waste stream. Returnable packaging must be designed by considering the trade-offs between costs and environmental impact to satisfy manufacturers and environmentalists alike. The cost of returnable packaging entails such items as materials, manufacturing, collection, storage and disposal. Environmental impacts are explicitly linked with solid waste, air pollution, and water pollution. This paper presents a multi-criteria evaluation technique to assist decision-makers for evaluating the trade-offs in costs and environmental impact during the returnable packaging design process. The proposed evaluation technique involves a combination of multiple objective integer linear programming and analytic hierarchy process. A numerical example is used to illustrate the methodology.

  14. Levee reliability analyses for various flood return periods - a case study in southern Taiwan

    NASA Astrophysics Data System (ADS)

    Huang, W.-C.; Yu, H.-W.; Weng, M.-C.

    2015-04-01

    In recent years, heavy rainfall conditions have caused disasters around the world. To prevent losses by floods, levees have often been constructed in inundation-prone areas. This study performed reliability analyses for the Chiuliao First Levee in southern Taiwan. The failure-related parameters were the water level, the scouring depth, and the in situ friction angle. Three major failure mechanisms were considered: the slope sliding failure of the levee and the sliding and overturning failures of the retaining wall. When the variability of the in situ friction angle and the scouring depth are considered for various flood return periods, the variations of the factor of safety for the different failure mechanisms show that the retaining wall sliding and overturning failures are more sensitive to the change of the friction angle. When the flood return period is greater than 2 years, the levee could fail with slope sliding for all values of the water level difference. The results of levee stability analysis considering the variability of different parameters could aid engineers in designing the levee cross sections, especially with potential failure mechanisms in mind.

  15. Mars Earth Return Vehicle (MERV) Propulsion Options

    NASA Technical Reports Server (NTRS)

    Oleson, Steven R.; McGuire, Melissa L.; Burke, Laura; Fincannon, James; Warner, Joe; Williams, Glenn; Parkey, Thomas; Colozza, Tony; Fittje, Jim; Martini, Mike; hide

    2010-01-01

    The COMPASS Team was tasked with the design of a Mars Sample Return Vehicle. The current Mars sample return mission is a joint National Aeronautics and Space Administration (NASA) and European Space Agency (ESA) mission, with ESA contributing the launch vehicle for the Mars Sample Return Vehicle. The COMPASS Team ran a series of design trades for this Mars sample return vehicle. Four design options were investigated: Chemical Return /solar electric propulsion (SEP) stage outbound, all-SEP, all chemical and chemical with aerobraking. The all-SEP and Chemical with aerobraking were deemed the best choices for comparison. SEP can eliminate both the Earth flyby and the aerobraking maneuver (both considered high risk by the Mars Sample Return Project) required by the chemical propulsion option but also require long low thrust spiral times. However this is offset somewhat by the chemical/aerobrake missions use of an Earth flyby and aerobraking which also take many months. Cost and risk analyses are used to further differentiate the all-SEP and Chemical/Aerobrake options.

  16. "Still Rather Hazy at Present": Citizens' and Physicians' Views on Returning Results from Biobank Research Using Broad Consent.

    PubMed

    Barazzetti, Gaia; Cavalli, Samuele; Benaroyo, Lazare; Kaufmann, Alain

    2017-03-01

    Informed consent and return of research results are among the most debated topics in the biobank literature. We discuss ethical, social, and policy issues associated with returning results in the context of biobanks using a broad consent approach, in the light of data from a qualitative survey of citizens' and physicians' views. Data were collected through interviews and focus groups to investigate stakeholders' perspectives about a large-scale hospital-based biobank designed to foster biomedical research, including prospective genomics research, and "personalized" medicine. Both physicians and citizens considered psychosocial impacts as crucial in the assessment of benefits expected from a return of results to biobank participants. In particular, physicians highlighted the possible consequences on the patient-doctor relationship and discussed implications for the concept of "personalized" medicine. Citizens held ambivalent attitudes toward returning individual research results: they defended the "right not to know," while they also considered a sort of "responsibility to know" because of potential implications of results for family members. Moreover, physicians and citizens raised questions about the broad consent model used for inhospital biobank recruitment and expressed their needs for more training in genomics and more information on the biobank initiative. Stakeholders such as citizens and physicians, who may be concerned as potential biobank participants or as healthcare professionals involved in the management of clinically relevant research results, provide useful insights into several aspects of broad consent and return of results, related in particular to the interface between research and the clinic.

  17. Return-to-play outcomes after microscopic lumbar diskectomy in professional athletes.

    PubMed

    Watkins, Robert G; Hanna, Robert; Chang, David; Watkins, Robert G

    2012-11-01

    It has been shown a microscopic lumbar diskectomy (MLD) is effective in getting professional athletes back to their sport after a herniated nucleus pulposus (HNP). There is a need for more information on the time it takes professional athletes to return after surgery. To determine average time for return to play and success in returning to play for professional athletes undergoing MLD. Case series; Level of evidence, 4. Between 1996 and 2010, the senior authors treated 171 professional athletes for lumbar HNP. A retrospective review was performed using patient charts, operative reports, team medical records, and internet search. Eighty-five patients were treated with MLD, and 86 patients were treated nonoperatively. This study focused on the return to play of the operatively treated patients. Primary outcome measures were return rate and average return time, considering only patients whose sport is in season at specific postoperative time points. Of surgically treated patients, 89.3% returned to sport. The average time it took operative patients to return to their sport (return time) was 5.8 months. Progressive return data for surgically treated patients showed the percentage of athletes who returned increased from 50% at 3 months to 72% at 6 months to 77% at 9 months and 84% at 12 months. The chance a player returns to play after MLD is 50% at 3 months, 72% at 6 months, 77% at 9 months, and 84% at 12 months. The overall chance of returning to play at any point is 89%.

  18. Excess entropy scaling for the segmental and global dynamics of polyethylene melts.

    PubMed

    Voyiatzis, Evangelos; Müller-Plathe, Florian; Böhm, Michael C

    2014-11-28

    The range of validity of the Rosenfeld and Dzugutov excess entropy scaling laws is analyzed for unentangled linear polyethylene chains. We consider two segmental dynamical quantities, i.e. the bond and the torsional relaxation times, and two global ones, i.e. the chain diffusion coefficient and the viscosity. The excess entropy is approximated by either a series expansion of the entropy in terms of the pair correlation function or by an equation of state for polymers developed in the context of the self associating fluid theory. For the whole range of temperatures and chain lengths considered, the two estimates of the excess entropy are linearly correlated. The scaled bond and torsional relaxation times fall into a master curve irrespective of the chain length and the employed scaling scheme. Both quantities depend non-linearly on the excess entropy. For a fixed chain length, the reduced diffusion coefficient and viscosity scale linearly with the excess entropy. An empirical reduction to a chain length-independent master curve is accessible for both dynamic quantities. The Dzugutov scheme predicts an increased value of the scaled diffusion coefficient with increasing chain length which contrasts physical expectations. The origin of this trend can be traced back to the density dependence of the scaling factors. This finding has not been observed previously for Lennard-Jones chain systems (Macromolecules, 2013, 46, 8710-8723). Thus, it limits the applicability of the Dzugutov approach to polymers. In connection with diffusion coefficients and viscosities, the Rosenfeld scaling law appears to be of higher quality than the Dzugutov approach. An empirical excess entropy scaling is also proposed which leads to a chain length-independent correlation. It is expected to be valid for polymers in the Rouse regime.

  19. Time-bound product returns and optimal order quantities for mass merchandisers

    NASA Astrophysics Data System (ADS)

    Yu, Min-Chun; Goh, Mark

    2012-01-01

    The return guidelines for a mass merchandiser usually entail a grace period, a markdown on the original price and the condition of the returned items. This research utilises eight scenarios formed from the variation of possible return guidelines to model the cost functions of single-product categories for a typical mass merchandiser. Models for the eight scenarios are developed and solved with the objective of maximising the expected profit so as to obtain closed form solutions for the associated optimal order quantity. An illustrative example and sensitivity analysis are provided to demonstrate the applicability of the model. Our results show that merchandisers who allow for returns within a time window, albeit with a penalty cost imposed and the returned products being recoverable, should plan for larger order amounts as such products do not affect the business. Similarly, the merchandisers who allow for returns beyond a grace period and without any penalty charges, but where the returned products are irrecoverable, should manage their stocks in this category more judiciously by ordering as little as possible so as to limit the number of returns and carefully consider the effects of their customer satisfaction-guaranteed policies, if any.

  20. The demographics of unfunded pensions.

    PubMed

    Keyfitz, N

    1985-01-01

    The performance of pay-as-you-go old-age insurance under different demographic conditions can be estimated from a metric consisting of the implicit rate of return to successive cohorts. The author shows a positive return for the prospective population over the next few years, but for cohorts born after the end of the century returns will become sharply negative. A decline in returns is typical of pay-as-you-go schemes as they mature, and a change to negative returns is typical in particular as the birth rate falls under fixed economic conditions. The return can be kept positive by greatly increased fertility or immigration. Taking labor-force participation rates into account, and supposing entitlement independent of contribution, gives much larger negative rates of return, however. The main calculations considered here are for schemes with a constant pension. If the contribution rather than the pension is kept constant then the disparities between cohorts with respect to their returns are smaller, and although the negative returns for future generations then set in earlier they are smaller. The conclusions of the paper are broadly applicable to any population that showed a baby boom after World War II and replacement-level or lower fertility subsequently.

  1. Net mitigation potential of straw return to Chinese cropland: estimation with a full greenhouse gas budget model.

    PubMed

    Lu, Fei; Wang, Xiaoke; Han, Bing; Ouyang, Zhiyun; Duan, Xiaonan; Zheng, Hua

    2010-04-01

    Based on the carbon-nitrogen cycles and greenhouse gas (GHG) mitigation and emission processes related to straw return and burning, a compound greenhouse gas budget model, the "Straw Return and Burning Model" (SRBM), was constructed to estimate the net mitigation potential of straw return to the soil in China. As a full GHG budget model, the SRBM addressed the following five processes: (1) soil carbon sequestration, (2) mitigation of synthetic N fertilizer substitution, (3) methane emission from rice paddies, (4) additional fossil fuel use for straw return, and (5) CH4 and N2O emissions from straw burning in the fields. Two comparable scenarios were created to reflect different degrees of implementation for straw return and straw burning. With GHG emissions and mitigation effects of the five processes converted into global warming potential (GWP), the net GHG mitigation was estimated. We concluded that (1) when the full greenhouse gas budget is considered, the net mitigation potential of straw return differs from that when soil carbon sequestration is considered alone; (2) implementation of straw return across a larger area of cropland in 10 provinces (i.e., Shanghai, Jiangsu, Zhejiang, Fujian, Jiangxi, Hubei, Hunan, Guangdong, Guangxi, and Hainan) will increase net GHG emission; (3) if straw return is promoted as a feasible mitigation measure in the remaining provinces, the total net mitigation potential before soil organic carbon (SOC) saturation will be 71.89 Tg CO2 equivalent (eqv)/yr, which is equivalent to 1.733% of the annual carbon emission from fossil fuel use in China in 2003; (4) after SOC saturation, only 13 of 21 provinces retain a relatively small but permanent net mitigation potential, while in the others the net GHG mitigation potential will gradually diminish; and (5) the major obstacle to the feasibility or permanence of straw return as a mitigation measure is the increased CH4 emission from rice paddies. The paper also suggests that comparable scenarios in which all the related carbon-nitrogen cycles are taken into account be created to estimate the mitigation potentials of organic wastes in different utilizations and treatments.

  2. A VaR Algorithm for Warrants Portfolio

    NASA Astrophysics Data System (ADS)

    Dai, Jun; Ni, Liyun; Wang, Xiangrong; Chen, Weizhong

    Based on Gamma Vega-Cornish Fish methodology, this paper propose the algorithm for calculating VaR via adjusting the quantile under the given confidence level using the four moments (e.g. mean, variance, skewness and kurtosis) of the warrants portfolio return and estimating the variance of portfolio by EWMA methodology. Meanwhile, the proposed algorithm considers the attenuation of the effect of history return on portfolio return of future days. Empirical study shows that, comparing with Gamma-Cornish Fish method and standard normal method, the VaR calculated by Gamma Vega-Cornish Fish can improve the effectiveness of forecasting the portfolio risk by virture of considering the Gamma risk and the Vega risk of the warrants. The significance test is conducted on the calculation results by employing two-tailed test developed by Kupiec. Test results show that the calculated VaRs of the warrants portfolio all pass the significance test under the significance level of 5%.

  3. Optimizing pricing and ordering strategies in a three-level supply chain under return policy

    NASA Astrophysics Data System (ADS)

    Noori-daryan, Mahsa; Taleizadeh, Ata Allah

    2018-03-01

    This paper develops an economic production quantity model in a three-echelon supply chain composing of a supplier, a manufacturer and a wholesaler under two scenarios. As the first scenario, we consider a return contract between the outside supplier and the supplier and also between the manufacturer and the wholesaler, but in the second one, the return policy between the manufacturer and the wholesaler is not applied. Here, it is assumed that shortage is permitted and demand is price-sensitive. The principal goal of the research is to maximize the total profit of the chain by optimizing the order quantity of the supplier and the selling prices of the manufacturer and the wholesaler. Nash-equilibrium approach is considered between the chain members. In the end, a numerical example is presented to clarify the applicability of the introduced model and compare the profit of the chain under two scenarios.

  4. Up-to-date modification of the anaerobic sludge digestion process introducing a separate sludge digestion mode.

    PubMed

    Sato, K; Ochi, S; Mizuochi, M

    2001-01-01

    Sewage treatment plants in Japan are subjected to advanced treatment to remove nutrients and hence control eutrophication problems in lakes and bays. This paper discusses the advantages and disadvantages of the separate digestion treatment mode for sludge generated from advanced wastewater treatment. In the separate digestion only primary sludge is digested and the excess activated sludge is directly dewatered. Separate digestion can reduce the return load of nutrients to approximately one third, and has major potential for the beneficial use of sludge.

  5. Work outcomes of sickness absence related to mental disorders: a systematic literature review

    PubMed Central

    Dewa, Carolyn S; Loong, Desmond; Bonato, Sarah

    2014-01-01

    Objectives The purpose of this systematic literature review is to examine the current state of knowledge regarding the return-to-work outcomes of sickness absences related to mental disorders that increase costs borne by employers. We address two questions: (1) Based on the existing literature, from the employer's perspective, what are the relevant economic return-to-work outcomes for sickness absences related to mental disorders? and (2) From the employer's economic perspective, are there gaps in knowledge about the relevant return-to-work outcomes for sickness absences related to mental disorders? Setting The included studies used administrative data from either an employer, insurer or occupational healthcare provider. Participants Studies included working adults between 18 and 65 years old who had a sickness absence related to a mental disorder. Primary and secondary outcome measures The studies considered two general return-to-work outcome categories: (1) outcomes focusing on return-to-work and (2) outcomes focusing on sickness absence recurrence. Results A total of 3820 unique citations were identified. Of these, 10 studies were identified whose quality ranged from good to excellent. Half of the identified studies came from one country. The studies considered two characteristics of sickness absence: (1) whether and how long it took for a worker to return-to-work and (2) sickness absence recurrence. None of the studies examined return-to-work outcomes related to work reintegration. Conclusions The existing literature suggests that along with the incidence of sickness absence related to mental disorders, the length of sickness absence episodes and sickness absence recurrence (ie, number and time between) should be areas of concern. However, there also seems to be gaps in the literature regarding the work reintegration process and its associated costs. PMID:25023133

  6. Estimation of Return Values of Wave Height: Consequences of Missing Observations

    ERIC Educational Resources Information Center

    Ryden, Jesper

    2008-01-01

    Extreme-value statistics is often used to estimate so-called return values (actually related to quantiles) for environmental quantities like wind speed or wave height. A basic method for estimation is the method of block maxima which consists in partitioning observations in blocks, where maxima from each block could be considered independent.…

  7. Losing Chlordimeform Use in Cotton Production. Its Effects on the Economy and Pest Resistance. Agricultural Economic Report Number 587.

    ERIC Educational Resources Information Center

    Osteen, Craig; Suguiyama, Luis

    This report examines the economic implications of losing chlordimeform use on cotton and considers chlordimeform's role in managing the resistance of bollworms and tobacco budworms to synthetic pyrethroids. It estimates changes in prices, production, acreage, consumer expenditures, aggregate producer returns, regional crop effects, and returns to…

  8. Development of a framework for the assessment of capacity and throughput technologies within the National Airspace System

    NASA Astrophysics Data System (ADS)

    Garcia, Elena

    The demand for air travel is expanding beyond the capacity of the existing National Airspace System. Excess traffic results in delays and compromised safety. Thus, a number of initiatives to improve airspace capacity have been proposed. To assess the impact of these technologies on air traffic one must move beyond the vehicle to a system-of-systems point of view. This top-level perspective must include consideration of the aircraft, airports, air traffic control and airlines that make up the airspace system. In addition to these components and their interactions economics, safety and government regulations must also be considered. Furthermore, the air transportation system is inherently variable with changes in everything from fuel prices to the weather. The development of a modeling environment that enables a comprehensive probabilistic evaluation of technological impacts was the subject of this thesis. The final modeling environment developed used economics as the thread to tie the airspace components together. Airport capacities and delays were calculated explicitly with due consideration to the impacts of air traffic control. The delay costs were then calculated for an entire fleet, and an airline economic analysis, considering the impact of these costs, was carried out. Airline return on investment was considered the metric of choice since it brings together all costs and revenues, including the cost of delays, landing fees for airport use and aircraft financing costs. Safety was found to require a level of detail unsuitable for a system-of-systems approach and was relegated to future airspace studies. Environmental concerns were considered to be incorporated into airport regulations and procedures and were not explicitly modeled. A deterministic case study was developed to test this modeling environment. The Atlanta airport operations for the year 2000 were used for validation purposes. A 2005 baseline was used as a basis for comparing the four technologies considered: a very large aircraft, Terminal Area Productivity air traffic control technologies, smoothing of an airline schedule, and the addition of a runway. A case including all four technologies simultaneously was also considered. Unfortunately, the complexity of the system prevented full exploration of the probabilistic aspects of the National Airspace System.

  9. Return to normality after a radiological emergency.

    PubMed

    Lochard, J; Prêtre, S

    1995-01-01

    Some preliminary considerations from the management of post-accident situations connected to large scale and high land contamination are presented. The return to normal, or at least acceptable living conditions, as soon as reasonably achievable, and the prevention of the possible emergence of a post-accident crisis is of key importance. A scheme is proposed for understanding the dynamics of the various phases after an accident. An attempt is made to characterize some of the parameters driving the acceptability of post-accident situations. Strategies to return to normal living conditions in contaminated areas are considered.

  10. Return to work and its relation to financial distress among Iranian cancer survivors.

    PubMed

    Ghasempour, Mostafa; Rahmani, Azad; Davoodi, Arefeh; Sheikhalipour, Zahra; Ziaeei, Jamal Evazie; Abri, Fariba

    2015-01-01

    Return to work after treatment completion is important for both cancer survivors and society. Financial distress is one of the factors that may influence the return to work in cancer survivors. However, this relationship has not been well investigated. This study aimed to determine the rate of return to work and its relation to financial distress among Iranian cancer survivors. This descriptive-correlational study was undertaken among 165 cancer survivors who completed their initial treatments and had no signs of active cancer. The Return to Work questionnaire and Financial Distress/Financial Well-Being Scale were used for data collection. Data were analyzed using SPSS statistical software. After initial treatments, 120 cancer survivors (72%) had returned to work, of which 50 patients (42%) had returned to full-time work and 70 (58%) reduced their work hours and returned to part-time work. Cancer survivors also reported high levels of financial distress. In addition, the financial distress was lower among patients who had returned completely to work, in comparison to patients who had quit working for cancer-related reasons (p=0.001) or returned to work as part-time workers (p=0.001). The findings showed that a high percent of Iranian cancer survivors had not returned to their jobs or considerably reduced working hours after treatment completion. Accordingly, due to high levels of financial distress experienced by participants and its relation to return to work, designing rehabilitation programs to facilitate cancer survivor return to work should be considered.

  11. Impact of the Volkswagen emissions control defeat device on US public health

    NASA Astrophysics Data System (ADS)

    Barrett, Steven R. H.; Speth, Raymond L.; Eastham, Sebastian D.; Dedoussi, Irene C.; Ashok, Akshay; Malina, Robert; Keith, David W.

    2015-11-01

    The US Environmental Protection Agency (EPA) has alleged that Volkswagen Group of America (VW) violated the Clean Air Act (CAA) by developing and installing emissions control system ‘defeat devices’ (software) in model year 2009-2015 vehicles with 2.0 litre diesel engines. VW has admitted the inclusion of defeat devices. On-road emissions testing suggests that in-use NOx emissions for these vehicles are a factor of 10 to 40 above the EPA standard. In this paper we quantify the human health impacts and associated costs of the excess emissions. We propagate uncertainties throughout the analysis. A distribution function for excess emissions is estimated based on available in-use NOx emissions measurements. We then use vehicle sales data and the STEP vehicle fleet model to estimate vehicle distance traveled per year for the fleet. The excess NOx emissions are allocated on a 50 km grid using an EPA estimate of the light duty diesel vehicle NOx emissions distribution. We apply a GEOS-Chem adjoint-based rapid air pollution exposure model to produce estimates of particulate matter and ozone exposure due to the spatially resolved excess NOx emissions. A set of concentration-response functions is applied to estimate mortality and morbidity outcomes. Integrated over the sales period (2008-2015) we estimate that the excess emissions will cause 59 (95% CI: 10 to 150) early deaths in the US. When monetizing premature mortality using EPA-recommended data, we find a social cost of ˜450m over the sales period. For the current fleet, we estimate that a return to compliance for all affected vehicles by the end of 2016 will avert ˜130 early deaths and avoid ˜840m in social costs compared to a counterfactual case without recall.

  12. Excess total organic carbon in the intermediate water of the South China Sea and its export to the North Pacific

    NASA Astrophysics Data System (ADS)

    Dai, Minhan; Meng, Feifei; Tang, Tiantian; Kao, Shu-Ji; Lin, Jianrong; Chen, Junhui; Huang-Chuan, Jr.; Tian, Jiwei; Gan, Jianping; Yang, Shuang

    2009-12-01

    Depth profiles of total organic carbon (TOC) were measured in spring (2005) and winter (2006) in the South China Sea (SCS), the largest marginal sea adjacent to the North Western Pacific (NWP). Compared to TOC profiles in the NWP, excess TOC (3.2 ± 1.1 μmol kg-1) was revealed in the intermediate layer of the SCS at σθ ˜ 27.2-27.6 (˜1000-1500 m). Below the depth of 2000 m, TOC concentrations were identical between the SCS and the NWP. Based on a one-dimensional steady state diffusion advection model constrained by potential temperature, we estimated a net TOC production rate of 0.12 ± 0.04 μmol kg-1 yr-1 to maintain this excess. A positive relationship between TOC and apparent oxygen utilization in the SCS deep water lent support to such a model-derived TOC production. This excess TOC in the out-flowing intermediate water may carry 3.1 ± 2.1 Tg C yr-1 of organic carbon out from the SCS and potentially into the deep open ocean. In light of the short residence time of the SCS deep water, the exported TOC was likely from the recently fixed organic carbon within the SCS. The export of such organic carbon, thereby less likely to return to the atmosphere may therefore contribute significantly to the carbon sequestration in the SCS.

  13. "Excess gooD can be Dangerous". A case series of iatrogenic symptomatic hypercalcemia due to hypervitaminosis D.

    PubMed

    Pandita, Kamal Kishore; Razdan, Sushil; Kudyar, Rattan Parkash; Beigh, Aadil; Kuchay, Shafi; Banday, Tanveer

    2012-05-01

    Vitamin D is increasingly recognized to have several beneficial effects. Its toxicity, causing hypercalcemia, is considered as extremely rare. We report case series of 15 patients (most of them being elderly subjects) with iatrogenic symptomatic hypercalcemia in whom toxicity occurred due to empirical excessive administration of vitamin D by oral and parenteral route.

  14. 10 CFR 100.11 - Determination of exclusion area, low population zone, and population center distance.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... these calculations should be based upon a major accident, hypothesized for purposes of site analysis or... exceeded by those from any accident considered credible. Such accidents have generally been assumed to... total radiation dose to the whole body in excess of 25 rem 2 or a total radiation dose in excess of 300...

  15. 10 CFR 100.11 - Determination of exclusion area, low population zone, and population center distance.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... these calculations should be based upon a major accident, hypothesized for purposes of site analysis or... exceeded by those from any accident considered credible. Such accidents have generally been assumed to... total radiation dose to the whole body in excess of 25 rem 2 or a total radiation dose in excess of 300...

  16. 10 CFR 100.11 - Determination of exclusion area, low population zone, and population center distance.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... these calculations should be based upon a major accident, hypothesized for purposes of site analysis or... exceeded by those from any accident considered credible. Such accidents have generally been assumed to... total radiation dose to the whole body in excess of 25 rem 2 or a total radiation dose in excess of 300...

  17. Can turned inward patella predict an excess of femoral anteversion during gait in spastic diplegic children?

    PubMed

    Simon, Anne-Laure; Presedo, Ana; Ilharreborde, Brice; Mallet, Cindy; Mazda, Keyvan; Penneçot, Georges-François

    2014-06-01

    Determining patellar orientation in the transverse plane during observational gait analysis is a fundamental aspect of physical examinations. Many physicians consider that an abnormal position of the patella in the transverse planes is only explained by a rotational abnormality of the proximal femur. A total of 188 spastic diplegic children with cerebral palsy were reviewed (376 lower limbs). The physical examination included observation of patellar orientation at midstride and measuring femoral anteversion (FA). All patients also underwent 3-dimensional (3D) computerized gait analysis of pelvic and hip rotation kinematics. Observational gait analysis and videotapes found 103 children (206 lower limbs) with inturned patella at midstance. Kinematic data from 3D gait analysis showed that the visual impression of turned inward patella was erroneous in 48 limbs. Of the remaining 158 lower limbs, 117 (74%) exhibited excessive FA and 41 (26%) did not. Of the 117 with excessive FA, kinematics showed only 66 (56%) with excessive internal hip rotation (with or without excessive internal pelvic rotation). Of the 41 lower limbs without excessive FA, 25 were explained by excessive internal pelvic rotation and 16 were explained by excessive internal hip rotation (isolated spasticity and/or contracture of internal rotator muscles). Turned inward patella was caused by isolated excessive internal pelvic rotation in 48%, excessive internal hip rotation in 35% (including 44 cases with excessive FA and 12 cases with isolated spasticity and/or contracture of internal hip rotators), and excessive internal hip rotation combined with excessive internal pelvic rotation in 17%. Excessive FA was not the only cause of turned inward patella gait and could not explain this gait anomaly by itself. Excessive internal pelvic rotation was the most frequent cause of turned inward patella gait. Level IV.

  18. Developing an event-tree probabilistic tsunami inundation model for NE Atlantic coasts: Application to case studies

    NASA Astrophysics Data System (ADS)

    Omira, Rachid; Baptista, Maria Ana; Matias, Luis

    2015-04-01

    This study constitutes the first assessment of probabilistic tsunami inundation in the NE Atlantic region, using an event-tree approach. It aims to develop a probabilistic tsunami inundation approach for the NE Atlantic coast with an application to two test sites of ASTARTE project, Tangier-Morocco and Sines-Portugal. Only tsunamis of tectonic origin are considered here, taking into account near-, regional- and far-filed sources. The multidisciplinary approach, proposed here, consists of an event-tree method that gathers seismic hazard assessment, tsunami numerical modelling, and statistical methods. It presents also a treatment of uncertainties related to source location and tidal stage in order to derive the likelihood of tsunami flood occurrence and exceedance of a specific near-shore wave height during a given return period. We derive high-resolution probabilistic maximum wave heights and flood distributions for both test-sites Tangier and Sines considering 100-, 500-, and 1000-year return periods. We find that the probability that a maximum wave height exceeds 1 m somewhere along the Sines coasts reaches about 55% for 100-year return period, and is up to 100% for 1000-year return period. Along Tangier coast, the probability of inundation occurrence (flow depth > 0m) is up to 45% for 100-year return period and reaches 96% in some near-shore costal location for 500-year return period. Acknowledgements: This work is funded by project ASTARTE - Assessment, STrategy And Risk Reduction for Tsunamis in Europe. Grant 603839, 7th FP (ENV.2013.6.4-3 ENV.2013.6.4-3).

  19. Does Distance Matter? A Study of Married Indian Women Professionals Staying Away from Families to Pursue Higher Studies

    ERIC Educational Resources Information Center

    Saxena, Richa; Bhatnagar, Deepti

    2018-01-01

    "Return to school" for enhancement of career is considered a means to career mobility. However, if "return to school" is chosen after a certain stage it has its own costs and challenges. It becomes more complex, especially for women, if geographical distance from family becomes an additional variable to it. Present study,…

  20. 43 CFR 426.13 - Excess land appraisals.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... cost methods, as applicable. Reclamation will consider nonproject water supply factors as provided in... standard appraisal procedures. (c) Appraisals of nonproject water supplies. (1) The appraiser will consider nonproject water supply factors, where appropriate, including: (i) Ground water pumping lift; (ii) Surface...

  1. Factors associated with failure to return for HIV test results in a free and anonymous screening centre.

    PubMed

    Laanani, Moussa; Dozol, Adrien; Meyer, Laurence; David, Stéphane; Camara, Sékou; Segouin, Christophe; Troude, Pénélope

    2015-07-01

    Free and anonymous screening centres (CDAG: Centres de Depistage Anononyme et Gratuit) are public facilities set up for HIV infection diagnosis in France. Some people visiting CDAG fail to return for test results and are not informed of their serology. This study aimed to assess factors associated with failure to return for HIV test results. Patients visiting the Fernand-Widal CDAG (Paris) for an HIV test in January-February 2011 were eligible to take part in the study. Data were collected with an anonymous self-administered questionnaire. Factors associated with failure to return were assessed using logistic regression models. Of the 710 participants (participation rate 88%), 46 patients failed to return. Not specifying birthplace and not living in the region of Paris were associated with failure to return. Those who perceived no risk of HIV infection and those who felt they were more at risk than other people were both statistically associated with failure to return. Self-perceived risk seemed to be of chief concern for failure to return for HIV test results and should be considered during pre-test counselling. © The Author(s) 2014.

  2. Multiple Smaller Missions as a Direct Pathway to Mars Sample Return

    NASA Technical Reports Server (NTRS)

    Niles, P. B.; Draper, D. S.; Evans, C. A.; Gibson, E. K.; Graham, L. D.; Jones, J. H.; Lederer, S. M.; Ming, D.; Seaman, C. H.; Archer, P. D.; hide

    2012-01-01

    Recent discoveries by the Mars Exploration Rovers, Mars Express, Mars Odyssey, and Mars Reconnaissance Orbiter spacecraft include multiple, tantalizing astrobiological targets representing both past and present environments on Mars. The most desirable path to Mars Sample Return (MSR) would be to collect and return samples from that site which provides the clearest examples of the variety of rock types considered a high priority for sample return (pristine igneous, sedimentary, and hydrothermal). Here we propose an MSR architecture in which the next steps (potentially launched in 2018) would entail a series of smaller missions, including caching, to multiple landing sites to verify the presence of high priority sample return targets through in situ analyses. This alternative architecture to one flagship-class sample caching mission to a single site would preserve a direct path to MSR as stipulated by the Planetary Decadal Survey, while permitting investigation of diverse deposit types and providing comparison of the site of returned samples to other aqueous environments on early Mars

  3. Aerothermodynamic environments for Mars entry, Mars return, and lunar return aerobraking missions

    NASA Astrophysics Data System (ADS)

    Rochelle, W. C.; Bouslog, S. A.; Ting, P. C.; Curry, D. M.

    1990-06-01

    The aeroheating environments to vehicles undergoing Mars aerocapture, earth aerocapture from Mars, and earth aerocapture from the moon are presented. An engineering approach for the analysis of various types of vehicles and trajectories was taken, rather than performing a benchmark computation for a specific point at a selected time point in a trajectory. The radiation into Mars using the Mars Rover Sample Return (MRSR) 2-ft nose radius bionic remains a small contributor of heating for 6 to 10 km/sec; however, at 12 km/sec it becomes comparable with the convection. For earth aerocapture, returning from Mars, peak radiation for the MRSR SRC is only 25 percent of the peak convection for the 12-km/sec trajectory. However, when large vehicles are considered with this trajectory, peak radiation can become 2 to 4 times higher than the peak convection. For both Mars entry and return, a partially ablative Thermal Protection System (TPS) would be required, but for Lunar Transfer Vehicle return an all-reusable TPS can be used.

  4. Changes in the Perceived Risk of Climate Change: Evidence from Sudden Climatic Events

    NASA Astrophysics Data System (ADS)

    Anttila-Hughes, J. K.

    2009-12-01

    In the course of the past two decades the threat of anthropogenic climate change has moved from a scientific concern of relative obscurity to become one of the largest environmental and public goods problems in history. During this period public understanding of the risk of climate change has shifted from negligible to quite large. In this paper I propose a means of quantifying this change by examining how sudden events supporting the theory of anthropogenic climate change have affected carbon intensive companies' stock prices. Using CAPM event study methodology for companies in several carbon-intensive industries, I find strong evidence that markets have been reacting to changes in the scientific evidence for climate change for some time. Specifically, the change in magnitude of response over time seems to indicate that investors believed climate change was a potentially serious risk to corporate profits as early as the mid 1990s. Moreover, market reaction dependence on event type indicates that investors are differentiating between different advances in the scientific knowledge. Announcements by NASA GISS that the previous year was a “record hot year” for the globe are associated with negative excess returns, while news of ice shelf collapses are associated with strong positive excess returns. These results imply that investors are aware of how different aspects of climate change will affect carbon intensive companies, specifically in terms of the link between warming in general and polar ice cover. This implies that policy choices based on observable public opinion have lagged actual private concern over climate change's potential threat.

  5. Mobilization of lead and other trace elements following shock chlorination of wells

    USGS Publications Warehouse

    Seiler, R.L.

    2006-01-01

    Many owners of domestic wells shock chlorinate their wells to treat for bacterial contamination or control bad odors from sulfides. Analysis of well water with four wells from Fallon, Nevada, showed that following recommended procedures for shock chlorinating wells can cause large, short-lasting increases in trace-element concentrations in ground water, particularly for Cu, Fe, Pb, and Zn. Lead concentrations increased up to 745 fold between samples collected just before the well was shock chlorinated and the first sample collected 22-24??h later; Zn concentrations increased up to 252 fold, Fe concentrations increased up to 114 fold, and Cu concentrations increased up to 29 fold. Lead concentrations returned to near background levels following pumping of about one casing volume, however, in one well an estimated 120??mg of excess Pb were pumped before concentrations returned to prechlorination levels. Total Pb concentrations were much greater than filtered (0.45????m) concentrations, indicating the excess Pb is principally particulate. Recommended procedures for purging treated wells following shock chlorination may be ineffective because a strong NaOCl solution can remain in the casing above the pump even following extended pumping. Only small changes in gross alpha and beta radioactivity occurred following shock chlorination. USEPA has not promulgated drinking-water standards for 210Pb, however, measured 210Pb activities in the study area typically were less than the Canadian Maximum Acceptable Concentration of 100??mBq/L. By consuming well water shortly after shock chlorination the public may inadvertently be exposed to levels of Pb, and possibly 210Pb, that exceed drinking-water standards.

  6. Assessment of the efficacy of a novel tailored vitamin K dosing regimen in lowering the International Normalised Ratio in over-anticoagulated patients: a randomised clinical trial.

    PubMed

    Kampouraki, Emmanouela; Avery, Peter J; Wynne, Hilary; Biss, Tina; Hanley, John; Talks, Kate; Kamali, Farhad

    2017-09-01

    Current guidelines advocate using fixed-doses of oral vitamin K to reverse excessive anticoagulation in warfarinised patients who are either asymptomatic or have minor bleeds. Over-anticoagulated patients present with a wide range of International Normalised Ratio (INR) values and response to fixed doses of vitamin K varies. Consequently a significant proportion of patients remain outside their target INR after vitamin K administration, making them prone to either haemorrhage or thromboembolism. We compared the performance of a novel tailored vitamin K dosing regimen to that of a fixed-dose regimen with the primary measure being the proportion of over-anticoagulated patients returning to their target INR within 24 h. One hundred and eighty-one patients with an index INR > 6·0 (asymptomatic or with minor bleeding) were randomly allocated to receive oral administration of either a tailored dose (based upon index INR and body surface area) or a fixed-dose (1 or 2 mg) of vitamin K. A greater proportion of patients treated with the tailored dose returned to within target INR range compared to the fixed-dose regimen (68·9% vs. 52·8%; P = 0·026), whilst a smaller proportion of patients remained above target INR range (12·2% vs. 34·0%; P < 0·001). Individualised vitamin K dosing is more accurate than fixed-dose regimen in lowering INR to within target range in excessively anticoagulated patients. © 2017 John Wiley & Sons Ltd.

  7. Levee reliability analyses for various flood return periods - a case study in Southern Taiwan

    NASA Astrophysics Data System (ADS)

    Huang, W.-C.; Yu, H.-W.; Weng, M.-C.

    2015-01-01

    In recent years, heavy rainfall conditions have caused damages around the world. To prevent damages by floods, levees have often been constructed in prone-to-inundation areas. This study performed reliability analyses for the Chiuliao 1st Levee located in southern Taiwan. The failure-related parameters were the water level, the scouring depth, and the in-situ friction angle. Three major failure mechanisms were considered, including the slope sliding failure of the levee, and the sliding and overturning failures of the retaining wall. When the variabilities of the in-situ friction angle and the scouring depth are considered for various flood return periods, the variations of the factor of safety (FS) for the different failure mechanisms show that the retaining wall sliding and overturning failures are more sensitive to the variability of the friction angle. When the flood return period is greater than 2 years, the levee can undergo slope sliding failure for all values of the water level difference. The results for levee stability analysis considering the variability of different parameters could assist engineers in designing the levee cross sections, especially with potential failure mechanisms in mind.

  8. Civic Returns to Higher Education: A Note on Heterogeneous Effects

    PubMed Central

    Brand, Jennie E.

    2011-01-01

    American educational leaders and philosophers have long valued schooling for its role in preparing the nation’s youth to be civically engaged citizens. Numerous studies have found a positive relationship between education and subsequent civic participation. However, little is known about possible variation in effects by selection into higher education, a critical omission considering education’s expressed role as a key mechanism for integrating disadvantaged individuals into civic life. I disaggregate effects and examine whether civic returns to higher education are largest for disadvantaged low likelihood or advantaged high likelihood college goers. I find evidence for significant effect heterogeneity: civic returns to college are greatest among individuals who have a low likelihood for college completion. Returns decrease as the propensity for college increases. PMID:22223924

  9. A quantum anharmonic oscillator model for the stock market

    NASA Astrophysics Data System (ADS)

    Gao, Tingting; Chen, Yu

    2017-02-01

    A financially interpretable quantum model is proposed to study the probability distributions of the stock price return. The dynamics of a quantum particle is considered an analog of the motion of stock price. Then the probability distributions of price return can be computed from the wave functions that evolve according to Schrodinger equation. Instead of a harmonic oscillator in previous studies, a quantum anharmonic oscillator is applied to the stock in liquid market. The leptokurtic distributions of price return can be reproduced by our quantum model with the introduction of mixed-state and multi-potential. The trend following dominant market, in which the price return follows a bimodal distribution, is discussed as a specific case of the illiquid market.

  10. SOCCER: Comet Coma Sample Return Mission

    NASA Technical Reports Server (NTRS)

    Albee, A. L.; Uesugi, K. T.; Tsou, Peter

    1994-01-01

    Comets, being considered the most primitive bodies in the solar system, command the highest priority among solar system objects for studying solar nebula evolution and the evolution of life through biogenic elements and compounds. Sample Of Comet Coma Earth Return (SOCCER), a joint effort between NASA and the Institute of Space and Astronautical Science (ISAS) in Japan, has two primary science objectives: (1) the imaging of the comet nucleus and (2) the return to Earth of samples of volatile species and intact dust. This effort makes use of the unique strengths and capabilities of both countries in realizing this important quest for the return of samples from a comet. This paper presents an overview of SOCCER's science payloads, engineering flight system, and its mission operations.

  11. Recommended treatment strategies for patients with excessive daytime sleepiness.

    PubMed

    Rosenberg, Russell P

    2015-10-01

    Excessive daytime sleepiness (EDS) is a common and bothersome phenomenon. It can be associated with insufficient sleep syndrome, narcolepsy, idiopathic hypersomnia, obstructive sleep apnea, shift work disorder, Kleine-Levin syndrome, or Parkinson's disease. Once the underlying cause of the excessive sleepiness is determined, clinicians must select the most appropriate behavioral and pharmacologic interventions to reduce daytime sleepiness, alleviate other symptoms, improve functioning, and ensure the safety of patients and those around them. Patient history, adverse effects, and efficacy in specific conditions should be considered in pharmacologic treatment options for patients with EDS. © Copyright 2015 Physicians Postgraduate Press, Inc.

  12. Low encounter speed comet COMA sample return missions

    NASA Technical Reports Server (NTRS)

    Tsou, P.; Yen, C. W.; Albee, A. L.

    1994-01-01

    Comets, being considered the most primitive bodies in the solar system, command the highest priority among solar-system objects for studying solar nebula evolution and the evolution of life through biogenic elements and compounds. The study of comets, and more especially, of material from them, provides an understanding of the physical, chemical, and mineralogical processes operative in the formation and earliest development of the solar systems. These return samples will provide valuable information on comets and serve as a rosetta stone for the analytical studies conducted on interplanetary dust particles over the past two decades, and will provide much needed extraterrestrial samples for the planetary materials community since the Apollo program. Lander sample return missions require rather complex spacecraft, intricate operations, and costly propulsion systems. By contrast, it is possible to take a highly simplified approach for sample capture and return in the case of a comet. In the past, we have considered Earth free-return trajectory to the comet, in which passive collectors intercept dust and volatiles from the cometary coma. However, standard short period cometary free-return trajectories results in the comet to the spacecraft encounter speeds in the range of 10 km/s. At these speeds the kinetic energy of the capture process can render significant modification of dust structure, change of solid phase as well as the lost of volatiles components. This paper presents a class of new missions with trajectories with significant reduction of encounter speeds by incorporating gravity assists and deep space maneuvering. Low encounter speed cometary flyby sample return will enable a marked increase in the value of the return science. Acquiring thousands of samples from a known comet and thousands of images of a comet nucleus would be space firsts. Applying new approach in flight mechanics to generate a new class of low encounter speed cometary sample return trajectories opens new possibilities in science. A systematic search of trajectories for the first decade of the twenty-first century will be made. The target encounter speed is for less than 7 km/s to short period comets.

  13. Management of Severe Rhabdomyolysis and Exercise-Associated Hyponatremia in a Female with Anorexia Nervosa and Excessive Compulsive Exercising

    PubMed Central

    2016-01-01

    This case report describes the management of a 49-year-old female with restricting-type anorexia nervosa and excessive compulsive exercising associated with rhabdomyolysis, high levels of serum creatine kinase (CK) (3,238 U/L), and marked hyponatremia (Na+: 123 mEq/L) in the absence of purging behaviours or psychogenic polydipsia; it is the first case report to describe exercise-associated hyponatremia in a patient with anorexia nervosa. The patient, who presented with a body mass index (BMI) of 13.4 kg/m2, was successfully treated by means of an adapted inpatient version of an enhanced form of cognitive behavioural therapy (CBT-E). Within a few days, careful water restriction, solute refeeding, and the specific cognitive behavioural strategies and procedures used to address the patient's excessive compulsive exercising and undereating produced a marked reduction in CK levels, which normalised within one week. Exercise-associated hyponatremia also gradually improved, with serum sodium levels returning to normal within two weeks. The patient thereby avoided severe complications such as cerebral or pulmonary oedema or acute renal failure and was discharged after 20 weeks of treatment with a BMI of 19.0 kg/m2 and improved eating disorder psychopathology. PMID:27721832

  14. Management of Severe Rhabdomyolysis and Exercise-Associated Hyponatremia in a Female with Anorexia Nervosa and Excessive Compulsive Exercising.

    PubMed

    El Ghoch, Marwan; Calugi, Simona; Dalle Grave, Riccardo

    2016-01-01

    This case report describes the management of a 49-year-old female with restricting-type anorexia nervosa and excessive compulsive exercising associated with rhabdomyolysis, high levels of serum creatine kinase (CK) (3,238 U/L), and marked hyponatremia (Na + : 123 mEq/L) in the absence of purging behaviours or psychogenic polydipsia; it is the first case report to describe exercise-associated hyponatremia in a patient with anorexia nervosa. The patient, who presented with a body mass index (BMI) of 13.4 kg/m 2 , was successfully treated by means of an adapted inpatient version of an enhanced form of cognitive behavioural therapy (CBT-E). Within a few days, careful water restriction, solute refeeding, and the specific cognitive behavioural strategies and procedures used to address the patient's excessive compulsive exercising and undereating produced a marked reduction in CK levels, which normalised within one week. Exercise-associated hyponatremia also gradually improved, with serum sodium levels returning to normal within two weeks. The patient thereby avoided severe complications such as cerebral or pulmonary oedema or acute renal failure and was discharged after 20 weeks of treatment with a BMI of 19.0 kg/m 2 and improved eating disorder psychopathology.

  15. An astrophysical engine that stores gravitational work as nuclear Coulomb energy

    NASA Astrophysics Data System (ADS)

    Clayton, Donald

    2014-03-01

    I describe supernovae gravity machines that store large internal nuclear Coulomb energy, 0.80Z2A- 1 / 3MeV per nucleus. Excess of it is returned later by electron capture and positron emission. Decay energy manifests as (1) observable gamma-ray lines (2) light curves of supernovae (3) chemical energy of free carbon dissociated from CO molecules (4) huge abundances of radiogenic daughters. I illustrate by rapid silicon burning, a natural epoch in SN II. Gravitational work produces the high temperatures that photoeject nucleons and alpha particles from heavy nuclei. These are retained by other nuclei to balance photoejection rates (quasiequilibrium). The abundance distribution adjusts slowly as remaining abundance of Z = N 28Si decomposes, so p, n, α recaptures hug the Z = N line. This occurs in milliseconds, too rapidly for weak decay to alter bulk Z/N ratio. The figure displays those quasiequilibrium abundances color-coded to their decays. Z = N = 2k nuclei having k < 11 are stable, whereas k > 10 are radioactive owing to excess Coulomb energy. Weak decays radiate that excess energy weeks later to fuel the four macroscopic energetic phenomena cited. How startling to think of the Coulomb nuclear force as storing cosmic energy and its weak decay releasing macroscopic activation to SNII.

  16. Biochar can be used to recapture essential nutrients from dairy wastewater and improve soil quality

    NASA Astrophysics Data System (ADS)

    Ghezzehei, T. A.; Sarkhot, D. V.; Berhe, A. A.

    2014-04-01

    Recently, the potential for biochar use to recapture excess nutrients from dairy wastewater has been a focus of a growing number of studies. It is suggested that biochar produced from locally available waste biomass can be important in reducing release of excess nutrient elements from agricultural runoff, improving soil productivity, and long-term carbon (C) sequestration. Here we present a review of a new approach that is showing promise for the use of biochar for nutrient capture. Using batch sorption experiments, it has been shown that biochar can adsorb up to 20 to 43% of ammonium and 19-65% of the phosphate in flushed dairy manure in 24 h. These results suggest a potential of biochar for recovering essential nutrients from dairy wastewater and improving soil fertility if the enriched biochar is returned to soil. Based on the sorption capacity of 2.86 and 0.23 mg ammonium and phosphate, respectively, per gram of biochar and 10-50% utilization of available excess biomass, in the state of California (US) alone, 11 440 to 57 200 t of ammonium-N and 920-4600 t of phosphate can be captured from dairy waste each year while at the same time disposing up to 8-40 million tons of waste biomass.

  17. Should excessive worry be required for a diagnosis of generalized anxiety disorder? Results from the US National Comorbidity Survey Replication.

    PubMed

    Ruscio, Ayelet Meron; Lane, Michael; Roy-Byrne, Peter; Stang, Paul E; Stein, Dan J; Wittchen, Hans-Ulrich; Kessler, Ronald C

    2005-12-01

    Excessive worry is required by DSM-IV, but not ICD-10, for a diagnosis of generalized anxiety disorder (GAD). No large-scale epidemiological study has ever examined the implications of this requirement for estimates of prevalence, severity, or correlates of GAD. Data were analyzed from the US National Comorbidity Survey Replication, a nationally representative, face-to-face survey of adults in the USA household population that was fielded in 2001-2003. DSM-IV GAD was assessed with Version 3.0 of the WHO Composite International Diagnostic Interview. Non-excessive worriers meeting all other DSM-IV criteria for GAD were compared with respondents who met full GAD criteria as well as with other survey respondents to consider the implications of removing the excessiveness requirement. The estimated lifetime prevalence of GAD increases by approximately 40% when the excessiveness requirement is removed. Excessive GAD begins earlier in life, has a more chronic course, and is associated with greater symptom severity and psychiatric co-morbidity than non-excessive GAD. However, non-excessive cases nonetheless evidence substantial persistence and impairment of GAD, high rates of treatment-seeking, and significantly elevated co-morbidity compared with respondents without GAD. Non-excessive cases also have sociodemographic characteristics and familial aggregation of GAD comparable to excessive cases. Individuals who meet all criteria for GAD other than excessiveness have a somewhat milder presentation than those with excessive worry, yet resemble excessive worriers in a number of important ways. These findings challenge the validity of the excessiveness requirement and highlight the need for further research into the optimal definition of GAD.

  18. Sample Return from Small Solar System Bodies

    NASA Astrophysics Data System (ADS)

    Orgel, L.; A'Hearn, M.; Bada, J.; Baross, J.; Chapman, C.; Drake, M.; Kerridge, J.; Race, M.; Sogin, M.; Squyres, S.

    With plans for multiple sample return missions in the next decade, NASA requested guidance from the National Research Council's SSB on how to treat samples returned from solar system bodies such as planetary satellites, asteroids and comets. A special Task Group assessed the potential for a living entity to be included in return samples from various bodies as well as the potential for large scale effects if such an entity were inadvertently introduced into the Earth's biosphere. The Group also assessed differences among solar system bodies, identified investigations that could reduce uncertainty about the bodies, and considered risks of returned samples compared to natural influx of material to the Earth in the form of interplanetary dust particles, meteorites and other small impactors. The final report (NRC, 1998) provides a decision making framework for future missions and makes recommendations on how to handle samples from different planetary satellites and primitive solar system bodies

  19. Results of the Compensated Earth-Moon-Earth Retroreflector Laser Link (CEMERLL) Experiment

    NASA Technical Reports Server (NTRS)

    Wilson, K. E.; Leatherman, P. R.; Cleis, R.; Spinhirne, J.; Fugate, R. Q.

    1997-01-01

    Adaptive optics techniques can be used to realize a robust low bit-error-rate link by mitigating the atmosphere-induced signal fades in optical communications links between ground-based transmitters and deep-space probes. Phase I of the Compensated Earth-Moon-Earth Retroreflector Laser Link (CEMERLL) experiment demonstrated the first propagation of an atmosphere-compensated laser beam to the lunar retroreflectors. A 1.06-micron Nd:YAG laser beam was propagated through the full aperture of the 1.5-m telescope at the Starfire Optical Range (SOR), Kirtland Air Force Base, New Mexico, to the Apollo 15 retroreflector array at Hadley Rille. Laser guide-star adaptive optics were used to compensate turbulence-induced aberrations across the transmitter's 1.5-m aperture. A 3.5-m telescope, also located at the SOR, was used as a receiver for detecting the return signals. JPL-supplied Chebyshev polynomials of the retroreflector locations were used to develop tracking algorithms for the telescopes. At times we observed in excess of 100 photons returned from a single pulse when the outgoing beam from the 1.5-m telescope was corrected by the adaptive optics system. No returns were detected when the outgoing beam was uncompensated. The experiment was conducted from March through September 1994, during the first or last quarter of the Moon.

  20. Interplanetary Mission Design Handbook: Earth-to-Mars Mission Opportunities and Mars-to-Earth Return Opportunities 2009-2024

    NASA Technical Reports Server (NTRS)

    George, L. E.; Kos, L. D.

    1998-01-01

    This paper provides information for trajectory designers and mission planners to determine Earth-Mars and Mars-Earth mission opportunities for the years 2009-2024. These studies were performed in support of a human Mars mission scenario that will consist of two cargo launches followed by a piloted mission during the next opportunity approximately 2 years later. "Porkchop" plots defining all of these mission opportunities are provided which include departure energy, departure excess speed, departure declination arrival excess speed, and arrival declinations for the mission space surrounding each opportunity. These plots are intended to be directly applicable for the human Mars mission scenario described briefly herein. In addition, specific trajectories and several alternate trajectories are recommended for each cargo and piloted opportunity. Finally, additional studies were performed to evaluate the effect of various thrust-to-weight ratios on gravity losses and total time-of-flight tradeoff, and the resultant propellant savings and are briefly summarized.

  1. Trends in Department of Defense hospital efficiency.

    PubMed

    Ozcan, Y A; Bannick, R R

    1994-04-01

    This study employs a simple cross sectional design using longitudinal data to explore the underlying factors associated with differences in hospital technical efficiency using data envelopment analysis (DEA) in the Department of Defense (DOD) sector across three service components, the Army, Air Force and Navy. The results suggest that the services do not differ significantly in hospital efficiency. Nor does hospital efficiency appear to differ over time. With respect to the efficient use of input resources, the services experienced a general decline in excessive usage of various inputs over the three years. Analysis of the returns to scale captures opportunities for planners of changing the relative mix of output to input slacks for increasing a hospital's efficiency. That is, policy makers would get more immediate "bang per buck" with emphasis on improving the efficiencies of hospitals with higher returns to scale than other hospitals. Findings also suggest a significant degree of comparability between the DEA measure and these measures often used to indicate efficiency.

  2. Correlated Microanalysis of Cometary Organic Grains Returned by Stardust

    NASA Technical Reports Server (NTRS)

    DeGregorio, B. T.; Stroud, R. M.; Nittler, L. R.; Cody, G. D,; Kilcoyne, A. L. D.

    2011-01-01

    Preliminary examination (PE) of samples returned from Comet 81P/Wild 2 by the NASA Stardust mission revealed a wide variety of carbonaceous samples [e.g. 1]. Carbonaceous matter is present as inclusions, rinds, and films in polyminerallic terminal particles [2-4], as carbon-rich particles along track walls [2, 5, 6], and as organic matter in aerogel around tracks [7, 8]. The organic chemistry of these samples ranges from purely aliphatic hydrocarbons to highly-aromatic material, often modified by various organic functional groups [2, 4, 5, 9-11]. Difficulty arises when interpreting the genesis of these carbonaceous samples, since contaminants could be introduced from the spacecraft [12], aerogel [1, 8], or during sample preparation. In addition, hypervelocity capture into aerogel may have heated cometary material in excess of 1000 C, which could have significantly altered the structure and chemistry of carbonaceous matter. Fortunately, much of this contamination or alteration can be identified through correlated microanalysis with transmission electron microscopy (TEM), scanning-transmission X-ray microscopy (STXM), and nanoscale secondary ion mass spectroscopy (SIMS).

  3. “Excess gooD can be Dangerous”. A case series of iatrogenic symptomatic hypercalcemia due to hypervitaminosis D

    PubMed Central

    Pandita, Kamal Kishore; Razdan, Sushil; Kudyar, Rattan Parkash; Beigh, Aadil; Kuchay, Shafi; Banday, Tanveer

    2012-01-01

    Summary Vitamin D is increasingly recognized to have several beneficial effects. Its toxicity, causing hypercalcemia, is considered as extremely rare. We report case series of 15 patients (most of them being elderly subjects) with iatrogenic symptomatic hypercalcemia in whom toxicity occurred due to empirical excessive administration of vitamin D by oral and parenteral route. PMID:23087723

  4. Investigation of Alternative Return Strategies for Orion Trans-earth Injection Design Options

    NASA Technical Reports Server (NTRS)

    Marchand, Belinda G.; Scarritt, Sara K.; Howell, Kathleen C.; Weeks, Michael W.

    2010-01-01

    The purpose of this study is to investigate alternative return strategies for the Orion trans-Earth injection (TEI) phase. A dynamical systems analysis approach considers the structure of the stable and unstable Sun perturbed Earth-Moon manifolds near the Earth-Moon interface region. A hybrid approach, then, combines the results from this analysis with classical two-body methods in a targeting process that seeks to expand the window of return opportunities in a precision entry scenario. The resulting startup arcs can be used, for instance, to enhance the block set of solutions available onboard during an autonomous targeting process.

  5. Dynamical Stochastic Processes of Returns in Financial Markets

    NASA Astrophysics Data System (ADS)

    Kim, Kyungsik; Kim, Soo Yong; Lim, Gyuchang; Zhou, Junyuan; Yoon, Seung-Min

    2006-03-01

    We show how the evolution of probability distribution functions of the returns from the tick data of the Korean treasury bond futures (KTB) and the S&P 500 stock index can be described by means of the Fokker-Planck equation. We derive the Fokker- Planck equation from the estimated Kramers-Moyal coefficients estimated directly from the empirical data. By analyzing the statistics of the returns, we present the quantitative deterministic and random influences on both financial time series, for which we can give a simple physical interpretation. Finally, we remark that the diffusion coefficient should be significantly considered to make a portfolio.

  6. Factors influencing return to work after illness in France.

    PubMed

    Pélissier, C; Fontana, L; Chauvin, F

    2014-01-01

    Few studies have been published about the factors influencing return to work after sickness absence. To identify medical and occupational factors influencing the type of fitness certificate given by occupational physicians before employees return to work after sickness absence. A cross-sectional study was undertaken over 3 months in several health services in France. Workers undergoing a medical examination before returning to work after a period of sickness absence of at least 3 weeks were included. Medical and occupational factors were collected using a questionnaire. The relationship between different factors and certification of fitness was assessed by univariate and multivariate analyses. Among the 402 workers included, 64% were considered fit to return to work. Being older, strenuous work, prolonged sick leave and fear of returning to work appeared to be negative factors influencing the return to a previous job. In contrast, having an education level higher than secondary school, being satisfied at work, perception of very good health and benefitting from satisfactory professional relationships appeared to favour return to work. We developed a predictive score of not being fit to return to work after illness. Our study highlighted the relationship between medical and occupational factors with problems returning to work. The predictive score may be used by occupational physicians as a screening tool to identify those who are likely to have difficulties returning to work after illness, so that their working conditions can be modified to take this into consideration.

  7. Physicians’ knowledge, perceptions, and attitudes toward antimicrobial prescribing in Riyadh, Saudi Arabia

    PubMed Central

    Baadani, Abeer M.; Baig, Kamran; Alfahad, Wafa A.; Aldalbahi, Sultan; Omrani, Ali S.

    2015-01-01

    Objectives: To assess knowledge, perceptions, and attitudes toward antimicrobial prescribing among physicians practicing in Riyadh, Saudi Arabia. Methods: A questionnaire was developed and distributed to physicians working in hospitals in Riyadh, Saudi Arabia between June and August 2013. The results were analyzed using Stata 12 software. Results: Two hundred and twelve (84.8%) full responses were returned. Most respondents perceived antimicrobial resistance as a significant problem in their daily practice (119, 56.1%) and at a national level (148, 69.8%). Inappropriate empirical therapy (101, 47.6%) and excessive use of antimicrobials in healthcare settings (66, 31.1%) were believed to be the main contributors to increasing bacterial resistance. Respondents favor treating infection rather than colonization (98, 46.2%), and physician education (74, 34.9%) as the most effective interventions to reduce antimicrobial resistance. Many respondents (95, 44.8%) do not feel confident in their knowledge of antimicrobial prescribing. Two-thirds of the respondents (135, 63.7%) have local antimicrobial guidelines, of which 90 (66.7%) felt were useful. Most respondents (160, 75.5%) considered their local infectious diseases service to be very helpful. Conclusion: There are considerable unmet training and education need for physicians in the area of antimicrobial prescribing. Local antimicrobial guidelines need revision to ensure they are more relevant and helpful for medical practitioners. PMID:25935184

  8. Generalized Separation of an Object Jettisoned from the ISS

    NASA Technical Reports Server (NTRS)

    Bacon, Jack; Menkin, Evgeny

    2006-01-01

    The International Space Station (ISS) Program faces unprecedented logistics challenges in both upmass and downmass. Some items employed on the ISS exterior present significant technical issues for a controlled de-orbit on either the shuttle or an expendable supply vehicle. Such manifest problems arise due to structural degradation, insufficient containment of hazardous pressures or contents, excessive size, or some combination of all of these factors. In addition, the mounting hardware and other flight service equipment to manifest the returned equipment must itself be launched, competing with other upmass. EVA techniques and equipment to successfully contain and secure such problematic equipment result in numerous significant risks to the spacewalking crews and cost and schedule risks to the program. The ISS Program office has therefore developed a policy that advises the jettison of the most problematic objects. Such jettisoned items join a small family of nearly co-planar orbital debris objects that threaten the ISS on several timescales, besides threatening all satellites with perigee below the ISS orbit and the general human population on Earth. This analysis addresses the governing physics and the ensuing risks when an object is jettisoned. It is shown that there are four time domains which must be considered, each with its own inherent problems, and that a ballistic solution is usually possible that satsfies all constraints in all domains.

  9. High-Capacity Communications from Martian Distances

    NASA Technical Reports Server (NTRS)

    Williams, W. Dan; Collins, Michael; Hodges, Richard; Orr, Richard S.; Sands, O. Scott; Schuchman, Leonard; Vyas, Hemali

    2007-01-01

    High capacity communications from Martian distances, required for the envisioned human exploration and desirable for data-intensive science missions, is challenging. NASA s Deep Space Network currently requires large antennas to close RF telemetry links operating at kilobit-per-second data rates. To accommodate higher rate communications, NASA is considering means to achieve greater effective aperture at its ground stations. This report, focusing on the return link from Mars to Earth, demonstrates that without excessive research and development expenditure, operational Mars-to-Earth RF communications systems can achieve data rates up to 1 Gbps by 2020 using technology that today is at technology readiness level (TRL) 4-5. Advanced technology to achieve the needed increase in spacecraft power and transmit aperture is feasible at an only moderate increase in spacecraft mass and technology risk. In addition, both power-efficient, near-capacity coding and modulation and greater aperture from the DSN array will be required. In accord with these results and conclusions, investment in the following technologies is recommended:(1) lightweight (1 kg/sq m density) spacecraft antenna systems; (2) a Ka-band receive ground array consisting of relatively small (10-15 m) antennas; (3) coding and modulation technology that reduces spacecraft power by at least 3 dB; and (4) efficient generation of kilowatt-level spacecraft RF power.

  10. The Effect of N-3 on N-2 Repetition Costs in Task Switching

    ERIC Educational Resources Information Center

    Schuch, Stefanie; Grange, James A.

    2015-01-01

    N-2 task repetition cost is a response time and error cost returning to a task recently performed after one intervening trial (i.e., an ABA task sequence) compared with returning to a task not recently performed (i.e., a CBA task sequence). This cost is considered a robust measure of inhibitory control during task switching. The present article…

  11. Statistics of rain-rate estimates for a single attenuating radar

    NASA Technical Reports Server (NTRS)

    Meneghini, R.

    1976-01-01

    The effects of fluctuations in return power and the rain-rate/reflectivity relationship, are included in the estimates, as well as errors introduced in the attempt to recover the unattenuated return power. In addition to the Hitschfeld-Bordan correction, two alternative techniques are considered. The performance of the radar is shown to be dependent on the method by which attenuation correction is made.

  12. Essential skills for students who are returning to study.

    PubMed

    Hendry, Charles; Farley, Alistair H

    Returning to study can be a stressful time for many students. In this article the authors consider ways in which studying at a university may differ from previous study experiences and explore how students can make best use of library and other resources. Studying at home has particular challenges and these are discussed as well as a range of skills that are essential to effective study.

  13. Surgical Ablation of Atrial Fibrillation Using Energy Sources.

    PubMed

    Brick, Alexandre Visconti; Braile, Domingo Marcolino

    2015-01-01

    Surgical ablation, concomitant with other operations, is an option for treatment in patients with chronic atrial fibrillation. The aim of this study is to present a literature review on surgical ablation of atrial fibrillation in patients undergoing cardiac surgery, considering energy sources and return to sinus rhythm. A comprehensive survey was performed in the literature on surgical ablation of atrial fibrillation considering energy sources, sample size, study type, outcome (early and late), and return to sinus rhythm. Analyzing studies with immediate results (n=5), the percentage of return to sinus rhythm ranged from 73% to 96%, while those with long-term results (n=20) (from 12 months on) ranged from 62% to 97.7%. In both of them, there was subsequent clinical improvement of patients who underwent ablation, regardless of the energy source used. Surgical ablation of atrial fibrillation is essential for the treatment of this arrhythmia. With current technology, it may be minimally invasive, making it mandatory to perform a procedure in an attempt to revert to sinus rhythm in patients requiring heart surgery.

  14. Time series regression-based pairs trading in the Korean equities market

    NASA Astrophysics Data System (ADS)

    Kim, Saejoon; Heo, Jun

    2017-07-01

    Pairs trading is an instance of statistical arbitrage that relies on heavy quantitative data analysis to profit by capitalising low-risk trading opportunities provided by anomalies of related assets. A key element in pairs trading is the rule by which open and close trading triggers are defined. This paper investigates the use of time series regression to define the rule which has previously been identified with fixed threshold-based approaches. Empirical results indicate that our approach may yield significantly increased excess returns compared to ones obtained by previous approaches on large capitalisation stocks in the Korean equities market.

  15. The Impact and Functional Outcomes of Achilles Tendon Pathology in National Basketball Association Players

    PubMed Central

    Amin, Nirav H; McCullough, Kirk C; Mills, Gavin L; Jones, Morgan H; Cerynik, Douglas L; Rosneck, James; Parker, Richard D

    2017-01-01

    Achilles tendon rupture within professional athletes has been shown to lead to devastating consequences regarding return to athletic performance. Not only can this devastating injury affect performance for the remainder of player's career, it frequently becomes a career-ending event. Considering these significant risks associated with complete rupture, the purpose of this study was to evaluate NBA players with a spectrum of reported Achilles tendon pathology, from tendinopathy (insertional and non-insertional) to complete rupture. Between the 1988-1989 and 2010-2011 NBA seasons, we identified 43 cases of Achilles tendon pathology treated non-operatively. A control group was matched for the players able to return to play with the following parameters: age, position played, number of seasons played in the league, and similarly rated career performance statistics. Considering the medical staff, trainers and facilities available to a professional athlete, a “weekend warrior” should be counseled that even in optimal conditions, 14% of NBA players were unable to return to function/play after Achilles tendinopathy, and that those who were able to return did so at a decreased level of performance. In conclusion, players with Achilles tendinopathy have a better chance to return if they are younger in age and early in their professional career. Furthermore, the association between Achilles pathology and decline in player performance is an important message to convey to coaching staff and team management to allow properly informed decisions when these conditions arise. PMID:29082269

  16. The Impact and Functional Outcomes of Achilles Tendon Pathology in National Basketball Association Players.

    PubMed

    Amin, Nirav H; McCullough, Kirk C; Mills, Gavin L; Jones, Morgan H; Cerynik, Douglas L; Rosneck, James; Parker, Richard D

    2016-09-01

    Achilles tendon rupture within professional athletes has been shown to lead to devastating consequences regarding return to athletic performance. Not only can this devastating injury affect performance for the remainder of player's career, it frequently becomes a career-ending event. Considering these significant risks associated with complete rupture, the purpose of this study was to evaluate NBA players with a spectrum of reported Achilles tendon pathology, from tendinopathy (insertional and non-insertional) to complete rupture. Between the 1988-1989 and 2010-2011 NBA seasons, we identified 43 cases of Achilles tendon pathology treated non-operatively. A control group was matched for the players able to return to play with the following parameters: age, position played, number of seasons played in the league, and similarly rated career performance statistics. Considering the medical staff, trainers and facilities available to a professional athlete, a "weekend warrior" should be counseled that even in optimal conditions, 14% of NBA players were unable to return to function/play after Achilles tendinopathy, and that those who were able to return did so at a decreased level of performance. In conclusion, players with Achilles tendinopathy have a better chance to return if they are younger in age and early in their professional career. Furthermore, the association between Achilles pathology and decline in player performance is an important message to convey to coaching staff and team management to allow properly informed decisions when these conditions arise.

  17. Modeling and forecasting of KLCI weekly return using WT-ANN integrated model

    NASA Astrophysics Data System (ADS)

    Liew, Wei-Thong; Liong, Choong-Yeun; Hussain, Saiful Izzuan; Isa, Zaidi

    2013-04-01

    The forecasting of weekly return is one of the most challenging tasks in investment since the time series are volatile and non-stationary. In this study, an integrated model of wavelet transform and artificial neural network, WT-ANN is studied for modeling and forecasting of KLCI weekly return. First, the WT is applied to decompose the weekly return time series in order to eliminate noise. Then, a mathematical model of the time series is constructed using the ANN. The performance of the suggested model will be evaluated by root mean squared error (RMSE), mean absolute error (MAE), mean absolute percentage error (MAPE). The result shows that the WT-ANN model can be considered as a feasible and powerful model for time series modeling and prediction.

  18. The returns and risks of investment portfolio in stock market crashes

    NASA Astrophysics Data System (ADS)

    Li, Jiang-Cheng; Long, Chao; Chen, Xiao-Dan

    2015-06-01

    The returns and risks of investment portfolio in stock market crashes are investigated by considering a theoretical model, based on a modified Heston model with a cubic nonlinearity, proposed by Spagnolo and Valenti. Through numerically simulating probability density function of returns and the mean escape time of the model, the results indicate that: (i) the maximum stability of returns is associated with the maximum dispersion of investment portfolio and an optimal stop-loss position; (ii) the maximum risks are related with a worst dispersion of investment portfolio and the risks of investment portfolio are enhanced by increasing stop-loss position. In addition, the good agreements between the theoretical result and real market data are found in the behaviors of the probability density function and the mean escape time.

  19. A New Lesson for eLearning Programs: "E" Is for Entrepreneurship.

    ERIC Educational Resources Information Center

    Robinson, Evan T.

    2002-01-01

    Considers how much entrepreneurship should be included in electronic learning (elearning) programs in higher education. Discusses planning; knowledge of the market; available resources in a usable form; considering new audiences; measuring ROI (return on investment); and alternative sources of revenue. (LRW)

  20. Introduction and Application of non-stationary Standardized Precipitation Index Considering Probability Distribution Function and Return Period

    NASA Astrophysics Data System (ADS)

    Park, J.; Lim, Y. J.; Sung, J. H.; Kang, H. S.

    2017-12-01

    The widely used meteorological drought index, the Standardized Precipitation Index (SPI) basically assumes stationarity, but recent change in the climate have led to a need to review this hypothesis. In this study, a new non-stationary SPI that considers not only the modified probability distribution parameter but also the return period under the non-stationary process has been proposed. The results are evaluated for two severe drought cases during the last 10 years in South Korea. As a result, SPIs considered the non-stationary hypothesis underestimated the drought severity than the stationary SPI despite these past two droughts were recognized as significantly severe droughts. It may be caused by that the variances of summer and autumn precipitation become larger over time then it can make the shape of probability distribution function wider than before. This understanding implies that drought expressions by statistical index such as SPI can be distorted by stationary assumption and cautious approach is needed when deciding drought level considering climate changes.

  1. Introduction and application of non-stationary standardized precipitation index considering probability distribution function and return period

    NASA Astrophysics Data System (ADS)

    Park, Junehyeong; Sung, Jang Hyun; Lim, Yoon-Jin; Kang, Hyun-Suk

    2018-05-01

    The widely used meteorological drought index, the Standardized Precipitation Index (SPI), basically assumes stationarity, but recent changes in the climate have led to a need to review this hypothesis. In this study, a new non-stationary SPI that considers not only the modified probability distribution parameter but also the return period under the non-stationary process was proposed. The results were evaluated for two severe drought cases during the last 10 years in South Korea. As a result, SPIs considered that the non-stationary hypothesis underestimated the drought severity than the stationary SPI despite that these past two droughts were recognized as significantly severe droughts. It may be caused by that the variances of summer and autumn precipitation become larger over time then it can make the probability distribution wider than before. This implies that drought expressions by statistical index such as SPI can be distorted by stationary assumption and cautious approach is needed when deciding drought level considering climate changes.

  2. Sewage sludge treatment system

    NASA Technical Reports Server (NTRS)

    Kalvinskas, John J. (Inventor); Mueller, William A. (Inventor)

    1976-01-01

    Raw sewage may be presently treated by mixing screened raw sewage with activated carbon. The mixture is then allowed to stand in a first tank for a period required to settle the suspended matter to the bottom of the tank as a sludge. Thereafter, the remaining liquid is again mixed with activated carbon and the mixture is transferred to a secondary settling tank, where it is permitted to stand for a period required for the remaining floating material to settle as sludge and for adsorption of sewage carbon as well as other impurities to take place. The sludge from the bottom of both tanks is removed and pyrolyzed to form activated carbon and ash, which is mixed with the incoming raw sewage and also mixed with the liquid being transferred from the primary to the secondary settling tank. It has been found that the output obtained by the pyrolysis process contains an excess amount of ash. Removal of this excess amount of ash usually also results in removing an excess amount of carbon thereby requiring adding carbon to maintain the treatment process. By separately pyrolyzing the respective sludges from the first and second settling tanks, and returning the separately obtained pyrolyzed material to the respective first and second tanks from which they came, it has been found that the adverse effects of the excessive ash buildup is minimized, the carbon yield is increased, and the sludge from the secondary tank can be pyrolyzed into activated carbon to be used as indicated many more times than was done before exhaustion occurs.

  3. Variety and volatility in financial markets

    NASA Astrophysics Data System (ADS)

    Lillo, Fabrizio; Mantegna, Rosario N.

    2000-11-01

    We study the price dynamics of stocks traded in a financial market by considering the statistical properties of both a single time series and an ensemble of stocks traded simultaneously. We use the n stocks traded on the New York Stock Exchange to form a statistical ensemble of daily stock returns. For each trading day of our database, we study the ensemble return distribution. We find that a typical ensemble return distribution exists in most of the trading days with the exception of crash and rally days and of the days following these extreme events. We analyze each ensemble return distribution by extracting its first two central moments. We observe that these moments fluctuate in time and are stochastic processes, themselves. We characterize the statistical properties of ensemble return distribution central moments by investigating their probability density functions and temporal correlation properties. In general, time-averaged and portfolio-averaged price returns have different statistical properties. We infer from these differences information about the relative strength of correlation between stocks and between different trading days. Last, we compare our empirical results with those predicted by the single-index model and we conclude that this simple model cannot explain the statistical properties of the second moment of the ensemble return distribution.

  4. Excessive quantities of red blood cells are issued to the operating room.

    PubMed

    Collins, R A; Wisniewski, M K; Waters, J H; Triulzi, D J; Alarcon, L H; Yazer, M H

    2015-12-01

    To determine what percentage of red blood cell (RBC) units that were issued to the operating room (OR) were returned unused, and to determine how often all of the RBCs that were issued for a patient were returned unused using the institution's maximum surgical blood ordering schedule (MSBOS) as a guide. The MSBOS provides guidelines for blood ordering, but is merely a suggestion for the ordering clinicians. This study examined how closely ordering practices followed the MSBOS, and how often ordered RBCs were actually transfused. For a 4-week period, RBC issue and utilization data were collected on elective surgery patients who were eligible for electronic cross-match at a tertiary care hospital. These data were compared to the MSBOS. There were 1350 surgical procedures performed. Of these cases, 439 patients had a type and screen (T&S) performed, and 215/439 (49%) patients had at least 1 RBC issued during their case. To these 215 patients, 742 RBC units were issued and 537/742 (72%) of these units were returned to the blood bank unused. In 152/215 (71%) cases with issued RBCs, all of the RBCs were returned to the blood bank unused. Amongst the surgical categories in this study, the percentage of cases where none of the issued RBCs were transfused ranged from 38 to 93%. Significant numbers of RBC units are issued but not transfused during surgery. Involving the surgical team in the blood issuing process and using a data-driven MSBOS may reduce the number of unused units. © 2015 British Blood Transfusion Society.

  5. Benefits of in situ propellant utilization for a Mars sample return mission

    NASA Technical Reports Server (NTRS)

    Wadel, Mary F.

    1993-01-01

    Previous Mars rover sample return mission studies have shown a requirement for Titan 4 or STS Space Shuttle launch vehicles to complete a sample return from a single Mars site. These studies have either used terrestrial propellants or considered in situ production of methane and oxygen for the return portion of the mission. Using in situ propellants for the return vehicles reduces the Earth launch mass and allows for a smaller Earth launch vehicle, since the return propellant is not carried from Earth. Carbon monoxide and oxygen (CO/O2) and methane and oxygen (CH4/O2) were investigated as in situ propellants for a Mars sample return mission and the results were compared to a baseline study performed by the Jet Propulsion Laboratory using terrestrial propellants. Capability for increased sample return mass, use of an alternate launch vehicle, and an additional mini-rover as payload were included. CO/O2 and CH4/O2 were found to decrease the baseline Earth launch mass by 13.6 and 9.2 percent, respectively. This resulted in higher payload mass margins for the baseline Atlas 2AS launch vehicle. CO/O2 had the highest mass margin. And because of this, it was not only possible to increase the sample return mass and carry an additional mini-rover, but was also possible to use the smaller Atlas 2A launch vehicle.

  6. Excess europium content in Precambrian sedimentary rocks and continental evolution

    NASA Technical Reports Server (NTRS)

    Jakes, P.; Taylor, S. R.

    1974-01-01

    It is proposed that the europium excess in Precambrian sedimentary rocks, relative to those of younger age, is derived from volcanic rocks of ancient island arcs, which were the source materials for the sediments. Precambrian sedimentary rocks and present-day volcanic rocks of island arcs have similar REE patterns, total REE abundances, and excess Eu, relative to the North American shale composite. The present upper crustal REE pattern, as exemplified by that of sediments, is depleted in Eu, relative to chondrites. This depletion is considered to be a consequence of development of a granodioritic upper crust by partial melting in the lower crust, which selectively retains europium.

  7. On the behavior of return stroke current and the remotely detected electric field change waveform

    NASA Astrophysics Data System (ADS)

    Shao, Xuan-Min; Lay, Erin; Jacobson, Abram R.

    2012-04-01

    After accumulating a large number of remotely recorded negative return stroke electric field change waveforms, a subtle but persistent kink was found following the main return stroke peak by several microseconds. To understand the corresponding return stroke current properties behind the kink and the general return stroke radiation waveform, we analyze strokes occurring in triggered lightning flashes for which have been measured both the channel base current and simultaneous remote electric radiation field. In this study, the channel base current is assumed to propagate along the return stroke channel in a dispersive and lossy manner. The measured channel base current is band-pass filtered, and the higher-frequency component is assumed to attenuate faster than the lower-frequency component. The radiation electric field is computed for such a current behavior and is then propagated to distant sensors. It is found that such a return stroke model is capable of very closely reproducing the measured electric waveforms at multiple stations for the triggered return strokes, and such a model is considered applicable to the common behavior of the natural return stroke as well. On the basis of the analysis, a number of other observables are derived. The time-evolving current dispersion and attenuation compare well with previously reported optical observations. The observable speed tends to agree with optical and VHF observations. Line charge density that is removed or deposited by the return stroke is derived, and the implication of the charge density distribution on leader channel decay is discussed.

  8. Economic Returns to Education: What We Know, What We Don't Know, and Where We Are Going-Some Brief Pointers

    ERIC Educational Resources Information Center

    Dickson, Matt; Harmon, Colm

    2011-01-01

    The estimation of the economic return to education has perhaps been one of the predominant areas of analysis in applied economics for over 50 years. In this short note we consider some of the recent directions taken by the literature, and also some of the blockages faced by both science and policymakers in pushing forward some key issues. This…

  9. Return probabilities and hitting times of random walks on sparse Erdös-Rényi graphs.

    PubMed

    Martin, O C; Sulc, P

    2010-03-01

    We consider random walks on random graphs, focusing on return probabilities and hitting times for sparse Erdös-Rényi graphs. Using the tree approach, which is expected to be exact in the large graph limit, we show how to solve for the distribution of these quantities and we find that these distributions exhibit a form of self-similarity.

  10. Invited review: Current representation and future trends of predicting amino acid utilization in the lactating dairy cow.

    PubMed

    Arriola Apelo, S I; Knapp, J R; Hanigan, M D

    2014-07-01

    In current dairy production systems, an average of 25% of dietary N is captured in milk, with the remainder being excreted in urine and feces. About 60% of total N losses occur postabsorption. Splanchnic tissues extract a fixed proportion of total inflow of each essential AA (EAA). Those EAA removed by splanchnic tissues and not incorporated into protein are subjected to catabolism, with the resulting N converted to urea. Splanchnic affinity varies among individual EAA, from several fold lower than mammary glands' affinity for the branched-chain AA to similar or higher affinity for Phe, Met, His, and Arg. On average, 85% of absorbed EAA appear in peripheral circulation, indicating that first-pass removal is not the main source of loss. Essential AA in excess of the needs of the mammary glands return to general circulation. High splanchnic blood flow dictates that a large proportion of EAA that return to general circulation flow through splanchnic tissues. In association with this constant recycling, EAA are removed and catabolized by splanchnic tissues. This results in splanchnic catabolism equaling or surpassing the use of many EAA for milk protein synthesis. Recent studies have demonstrated that EAA, energy substrates, and hormones activate signaling pathways that in turn regulate local blood flow, tissue extraction of EAA, and rates of milk protein synthesis. These recent findings would allow manipulation of dairy diets to maximize mammary uptake of EAA and reduce catabolism by splanchnic tissues. Dairy cattle nutrient requirement systems consider EAA requirements in aggregate as metabolizable protein (MP) and assume a fixed efficiency of MP use for milk protein. Lysine and Met sufficiency is only considered after MP requirements have been met. By doing so, requirement systems limit the scope of diet manipulation to achieve improved gross N efficiency. Therefore, this review focuses on understanding the dynamics of EAA metabolism in mammary and splanchnic tissues that would lead to improved requirement prediction systems. Inclusion of variable individual EAA efficiencies derived from splanchnic and mammary responses to nutrient and hormonal signals should help reduce dietary protein levels. Supplementing reduced crude protein diets with individual EAA should increase gross N efficiency to more than 30%, reducing N excretion by the US dairy industry by 92,000 t annually. Copyright © 2014 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  11. River water quality management considering agricultural return flows: application of a nonlinear two-stage stochastic fuzzy programming.

    PubMed

    Tavakoli, Ali; Nikoo, Mohammad Reza; Kerachian, Reza; Soltani, Maryam

    2015-04-01

    In this paper, a new fuzzy methodology is developed to optimize water and waste load allocation (WWLA) in rivers under uncertainty. An interactive two-stage stochastic fuzzy programming (ITSFP) method is utilized to handle parameter uncertainties, which are expressed as fuzzy boundary intervals. An iterative linear programming (ILP) is also used for solving the nonlinear optimization model. To accurately consider the impacts of the water and waste load allocation strategies on the river water quality, a calibrated QUAL2Kw model is linked with the WWLA optimization model. The soil, water, atmosphere, and plant (SWAP) simulation model is utilized to determine the quantity and quality of each agricultural return flow. To control pollution loads of agricultural networks, it is assumed that a part of each agricultural return flow can be diverted to an evaporation pond and also another part of it can be stored in a detention pond. In detention ponds, contaminated water is exposed to solar radiation for disinfecting pathogens. Results of applying the proposed methodology to the Dez River system in the southwestern region of Iran illustrate its effectiveness and applicability for water and waste load allocation in rivers. In the planning phase, this methodology can be used for estimating the capacities of return flow diversion system and evaporation and detention ponds.

  12. Incidental genetic findings in randomized clinical trials: recommendations from the Genomics and Randomized Trials Network (GARNET)

    PubMed Central

    2013-01-01

    Recommendations and guidance on how to handle the return of genetic results to patients have offered limited insight into how to approach incidental genetic findings in the context of clinical trials. This paper provides the Genomics and Randomized Trials Network (GARNET) recommendations on incidental genetic findings in the context of clinical trials, and discusses the ethical and practical issues considered in formulating our recommendations. There are arguments in support of as well as against returning incidental genetic findings in clinical trials. For instance, reporting incidental findings in clinical trials may improve the investigator-participant relationship and the satisfaction of participation, but it may also blur the line between clinical care and research. The issues of whether and how to return incidental genetic findings, including the costs of doing so, should be considered when developing clinical trial protocols. Once decided, plans related to sharing individual results from the aim(s) of the trial, as well as incidental findings, should be discussed explicitly in the consent form. Institutional Review Boards (IRBs) and other study-specific governing bodies should be part of the decision as to if, when, and how to return incidental findings, including when plans in this regard are being reconsidered. PMID:23363732

  13. Risk management considerations and the pregnancy handheld record. An audit of the return rate of the pregnancy handheld record.

    PubMed

    Toohill, Jocelyn; Soong, Barbara; Meldrum, Melissa

    2006-12-01

    Risk management is integral to the provision of contemporary health care. As maternity practices change and with a commitment on women being at the centre of care, one strategy has been for women to retain their records during the antenatal period. This paper explores the return rate of the pregnancy handheld record in a major tertiary facility and discusses the risk management implications when the record is not available upon presentation to the treating practitioner. Four audits were conducted over a 2 year period to determine the return rate of the pregnancy handheld record at time of admission for labour and birth. A total of 1096 records were returned out of a possible 1256 during the study. A 6.6% increase in the return rate was achieved over the 4 audit periods (82-88.5%) with an overall return rate of 85%. Our audit highlights the need for consumers, clinicians and heath care facilities to consider the advantages and disadvantages of the pregnancy handheld record, as well as the medico-legal responsibilities that ultimately fall back on the health facility.

  14. Impact of atmospheric uncertainties and viscous interaction effects on the performance of aeroassisted orbital transfer vehicles

    NASA Technical Reports Server (NTRS)

    Talay, T. A.; White, N. H.; Naftel, J. C.

    1984-01-01

    Simulations of aerobraking trajectories of aeroassisted orbital transfer vehicles (AOTV's) returning from geosynchronous orbit were analyzed to examine the effects of high-altitude viscous interactions and off-nominal atmospheres on AOTV return weight, heating, and loads performance. Viscous interaction effects encountered at high altitudes had little detrimental effect on the return weight capabilities for AOTV's representing a range of lift/drag ratios. Most of the AOTV return weight increase over an all-propulsive OTV occurred for a low lift/drag ratio. Smaller increases in return weight were observed for higher lift/drag ratios, at the expense of significantly higher heating and aerodynamic loads. Off-nominal atmospheres based on Shuttle-derived data and multipliers on a U.S. Standard Atmosphere were considered. AOTV's intended for entry under standard atmospheric conditions either deorbited during the pass through the off-nominal atmospheres or missed the target phasing orbit by wide margins. The AOTV's could successfully negotiate these atmospheres when new bank-angle histories were implemented with little loss and sometimes with a gain in return weight.

  15. Contribution of Sudanese medical diaspora to the healthcare delivery system in Sudan: exploring options and barriers.

    PubMed

    Abdalla, Fayrouz Mohammed; Omar, Maye Abu; Badr, Elsheikh Elsiddig

    2016-06-30

    Medical diaspora options, including the engagement of expatriate physicians in development efforts within their home country, are being called for to reverse the effects of brain drain from developing countries. This paper presents the results of a study exploring the potential contributions for the Sudanese Medial Diaspora Options to the healthcare delivery system (HCDS) in Sudan, focusing on the options of temporal and permanent returns and the likely obstacles faced in their implementation. This was a cross-sectional study using a mixed methods design including quantitative and qualitative approaches. For the quantitative approach, the study, which focused on the possible contribution of the diaspora to healthcare delivery in Sudan, was based on an online survey using random purposive and snowballing sampling techniques involving 153 Sudanese physicians working in Saudi Arabia and other Gulf States, the United Kingdom, the Republic of Ireland, and the United States of America. The qualitative approach involved in-depth interviews with returnee physicians and key informants in Sudan, focusing on the return experiences, the barriers for return, and the options to improve future contributions. Despite contributions of the Sudanese medical diaspora being of a small scale considering the size of the phenomenon, as well as infrequent and not appropriately organized, their inputs to academia and the links built with overseas institutions and specialist clinical services were nevertheless remarkable. The main barrier to temporal return was inappropriate organization by the local counterparts, while those for permanent return of physicians were poor work environment, insufficient financial payment, unsecured accommodation, and offspring education. The study identified short-term return as a feasible option considering the country's current conditions. Proper coordination mechanisms for short-term returns and facilitation of permanent return through stakeholders' collaboration were proposed to improve diaspora contributions. The potentials of Sudanese medial diaspora contributions to the HCDS in Sudan are promising. Short-term contributions were observed as the best option for the current country situation. Creation of a coordinating body from within the healthcare sector in Sudan to effectively coordinate diaspora contributions is recommended.

  16. Static vs stochastic optimization: A case study of FTSE Bursa Malaysia sectorial indices

    NASA Astrophysics Data System (ADS)

    Mamat, Nur Jumaadzan Zaleha; Jaaman, Saiful Hafizah; Ahmad, Rokiah@Rozita

    2014-06-01

    Traditional portfolio optimization methods in the likes of Markowitz' mean-variance model and semi-variance model utilize static expected return and volatility risk from historical data to generate an optimal portfolio. The optimal portfolio may not truly be optimal in reality due to the fact that maximum and minimum values from the data may largely influence the expected return and volatility risk values. This paper considers distributions of assets' return and volatility risk to determine a more realistic optimized portfolio. For illustration purposes, the sectorial indices data in FTSE Bursa Malaysia is employed. The results show that stochastic optimization provides more stable information ratio.

  17. Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.

    PubMed

    Bailey, George S; Reddy, Ashok P; Pereira, Clifford B; Harttig, Ulrich; Baird, William; Spitsbergen, Jan M; Hendricks, Jerry D; Orner, Gayle A; Williams, David E; Swenberg, James A

    2009-07-01

    Assessment of human cancer risk from animal carcinogen studies is severely limited by inadequate experimental data at environmentally relevant exposures and by procedures requiring modeled extrapolations many orders of magnitude below observable data. We used rainbow trout, an animal model well-suited to ultralow-dose carcinogenesis research, to explore dose-response down to a targeted 10 excess liver tumors per 10000 animals (ED(001)). A total of 40800 trout were fed 0-225 ppm dibenzo[a,l]pyrene (DBP) for 4 weeks, sampled for biomarker analyses, and returned to control diet for 9 months prior to gross and histologic examination. Suspect tumors were confirmed by pathology, and resulting incidences were modeled and compared to the default EPA LED(10) linear extrapolation method. The study provided observed incidence data down to two above-background liver tumors per 10000 animals at the lowest dose (that is, an unmodeled ED(0002) measurement). Among nine statistical models explored, three were determined to fit the liver data well-linear probit, quadratic logit, and Ryzin-Rai. None of these fitted models is compatible with the LED(10) default assumption, and all fell increasingly below the default extrapolation with decreasing DBP dose. Low-dose tumor response was also not predictable from hepatic DBP-DNA adduct biomarkers, which accumulated as a power function of dose (adducts = 100 x DBP(1.31)). Two-order extrapolations below the modeled tumor data predicted DBP doses producing one excess cancer per million individuals (ED(10)(-6)) that were 500-1500-fold higher than that predicted by the five-order LED(10) extrapolation. These results are considered specific to the animal model, carcinogen, and protocol used. They provide the first experimental estimation in any model of the degree of conservatism that may exist for the EPA default linear assumption for a genotoxic carcinogen.

  18. Survey of current status of intensive care teaching in English-speaking medical schools.

    PubMed

    Shen, Judith; Joynt, Gavin M; Critchley, Lester A H; Tan, Ian K S; Lee, Anna

    2003-01-01

    To identify a consensus of opinion regarding the content of an intensive care core syllabus for undergraduate medical students and factors that may limit its teaching. Cross-sectional postal survey containing 35 items ranging from department structure to curriculum content and factors that limit the teaching of intensive care. English-speaking medical schools (n = 210) listed in the 1986 World Health Organization Directory. Of 122 (58%) returned questionnaires, a 45% return was achieved from the United States and 86% from non-U.S. countries. Most respondents (84%) considered teaching undergraduate intensive care to be essential; however, teaching intensive care was compulsory in only 31% of schools. Many schools (43%) reported recent changes to their intensive care curriculum. Most respondents (60%) thought that intensive care specialists should teach and that each student required a median (interquartile range) of 20 (10-80) hrs of teacher contact time. Resuscitation skills were taught in 98% of schools. In comparison, 63% of schools had no intensive care syllabus. More than 90% of respondents thought that the intensive care syllabus should include the following: cardiopulmonary resuscitation, assessment and management of the acutely ill patient; management of respiratory, circulatory, and multiple organ system failure (including systemic inflammatory response syndrome and sepsis); management of the unconscious patient; early postoperative care; and communication skills and ethics as they relate to end-of-life issues. Factors that limited intensive care teaching were lack of staff, funding, and time dedicated to teaching and excessive clinical workload. Student performance in intensive care was assessed by 66% of schools, but only 28% used a written or oral examination. By surveying a wide range of medical schools internationally, we have been able to define an undergraduate intensive care syllabus that could be delivered in 20 hrs or 1 wk of dedicated teaching time. Factors that impede the provision of undergraduate intensive care teaching are a lack of staff, funding, and dedicated teaching time.

  19. Explaining a CMS e e j j excess with R -parity violating supersymmetry and implications for neutrinoless double beta decay

    NASA Astrophysics Data System (ADS)

    Allanach, Ben; Biswas, Sanjoy; Mondal, Subhadeep; Mitra, Manimala

    2015-01-01

    A recent CMS search for the right-handed gauge boson WR reports an interesting deviation from the Standard Model. The search has been conducted in the e e j j channel and has shown a 2.8 σ excess around me e j j˜2 TeV . In this work, we explain the reported CMS excess with R -parity violating supersymmetry. We consider resonant selectron and sneutrino production, followed by the three body decays of the neutralino and chargino via an R -parity violating coupling. We fit the excess for slepton masses around 2 TeV. The scenario can further be tested in neutrinoless double beta decay (0 ν β β ) experiments. GERDA Phase-II will probe a significant portion of the good-fit parameter space.

  20. Solvation of excess electrons trapped in charge pockets on molecular surfaces

    NASA Astrophysics Data System (ADS)

    Jalbout, Abraham F.

    This work considers the ability of hydrogen fluoride (HF) to solvate excess electrons located on cyclic hydrocarbon surfaces. The principle applied involves the formation of systems in which excess electrons can be stabilized not only on concentrated molecular surface charge pockets but also by HF. Recent studies have shown that OH groups can form stable hydrogen-bonded networks on one side of a hydrocarbon surface (i.e. cyclohexane sheets), at the same time, the hydrogen atoms on the opposite side of this surface form a pocket of positive charge can attract the excess electron. This density can be further stabilized by the addition of an HF molecule that can form an 'anion with an internally solvated electron' (AISE) state. These systems are shown to be stable with respect to vertical electron detachment (VDE).

  1. Return of separated children: the impact of Dutch policies.

    PubMed

    Kromhout, Mariska

    2011-01-01

    In many European countries, both the voluntary and the forced return of rejected asylum seekers are problematic. In the case of separated children, the difficulties seem to be even greater. In the Netherlands, many of these children disappear from the reception centres for unknown destinations, instead of returning to their home country. The new, stricter return policies adopted by the Dutch government in recent years have not (yet) changed this situation.In an explorative study of separated children aged between 15 and 18, the implementation and results of these policies were studied. The impact of the activities designed to promote voluntary return appeared to be very limited. Most separated young people did not want to consider return and did not take any action in this regard. Forced return rarely constituted a viable alternative. These findings may be explained by several factors. Among other things, considerations pertaining to personal security, family circumstances, and structural conditions in the countries of origin influence both the attitudes and behaviours of separated children, and host government policies. Moreover, many children were not willing to discuss their return with the youth care workers who were supposed to discuss and promote a voluntary return with them. The fact that most of the young people were allowed to stay in the reception centres until their eighteenth birthday enabled them to postpone making a final decision. A forced return was hindered by such obstacles as the absence of documents and the lack of appropriate care in the country of origin. More insight into the backgrounds of separated children and the (im)possibilities regarding their return seems necessary to be able to design more effective return policies.

  2. Different forms, reasons and motivations for return migration of persons who voluntarily decide to return to their countries of origin.

    PubMed

    Callea, S

    1986-03-01

    Although the 1973 oil crisis did not have the drastic effects on immigration which were originally feared, it did end a period of quasi-liberal immigration policy, establish intense and effective international cooperation on immigration, and arouse great interest in immigration studies and research. This paper analyzes the situations arising as a result of the petroleum shortage and focuses on the conditions relating to the return of emigrants to Southern European countries. This new research draws attention to the following fundamental aspects of the immigration problem: 1) the emigrant's return to his homeland cannot be considered a factor in development; it is a positive element in development only if the right socioeconomic conditions exist in the country of origin. 2) Concern for children's education is one of the most common reasons for return. 3) A large percentage of emigrants are satisfied with their work abroad. 4) An emigrant's return potential is wasted due to the slight use that is made of the resources he offers. 5) Returning workers most often want to set up an independent enterprise. 6) Savings are generally used to buy a house or farm. 7) Vocational level does not increase significantly between emigration and returning, though this increase becomes greater the longer the emigrant stays abroad. 8) The number of returning emigrants is too slight to bring about any change in the country of origin. 9) Incentives and subsidies to encourage return have not had a considerable impact on the decision to return. Callea recommends that officials of the country of origin posted abroad be assigned to counsel returning emigrants on finding employment, attending vocational development courses, obtaining housing, accruing interests and savings, and on the problems and perspectives of sociocultural reintegration.

  3. Return to sport after ACL reconstruction: a survey between the Italian Society of Knee, Arthroscopy, Sport, Cartilage and Orthopaedic Technologies (SIGASCOT) members.

    PubMed

    Grassi, Alberto; Vascellari, Alberto; Combi, Alberto; Tomaello, Luca; Canata, Gian Luigi; Zaffagnini, Stefano

    2016-07-01

    A worldwide consensus for timing and criteria for return to sport after anterior cruciate ligament (ACL) reconstruction is lacking. The aim of the study was to survey among the Italian Society of Knee, Arthroscopy, Sport, Cartilage and Orthopaedic Technologies (SIGASCOT) members in order to evaluate their approaches to the return to sport after ACL reconstruction regarding timing and criteria. A web survey among the SIGASCOT members was performed, including 14 questions regarding technical and graft preferences, timing for return to training and competitive activity for contact and non-contact sports and criteria to allow return to sport. Totally, 123 members completed the questionnaire. Return to training sports was allowed within 6 month by 87 % for non-contact sports and by 53 % for contact sports. Return to competitive activity was allowed within 6 months by 48 % for non-contact sports and by 13 % for contact sports. Full ROM (77 %), Lachman test (65 %) and Pivot-Shift test (65 %) were the most used criteria to allow return to sport. The 90 % used at least one clinical score. The SIGASCOT members showed various approaches in the return to sport after ACL reconstruction, with differences between return to training or competitive activity, and between contact and non-contact sports. Six months was generally considered adequate by most of the members for the most demanding activities. The most used criteria to allow return to sport were manual testing. A clear definition of sport activities and more objective criteria for the return to sport are needed. Level V, expert opinion.

  4. The effect that energy storage and return feet have on the propulsion of the body: a pilot study.

    PubMed

    Crimin, Anthony; McGarry, Anthony; Harris, Elena Jane; Solomonidis, Stephan Emanuel

    2014-09-01

    A variety of energy storage and return prosthetic feet are currently available for use within lower limb prostheses. Designs claim to provide a beneficial energy return during push-off, but the extent to which this occurs remains disputed. Techniques currently used to measure energy storage, dissipation and return within the structure of the prosthetic foot are debatable, with limited evidence to support substantial elastic energy storage and return from existing designs. The aim of this study was to evaluate the performance of energy storage and return foot designs through considering the ankle power during push-off and the effect on body centre of mass propulsion. To achieve this aim, the gait patterns of six trans-tibial prosthetic users wearing different designs of energy storage and return feet were analysed while ascending a ramp. Three examples of energy storage and return feet (suitable for moderate activity) were selected and randomly evaluated: the Blatchford's Epirus, Össur Assure and College Park Tribute feet. The power at the anatomical and mechanical ankle joints was integrated to evaluate the work done over the gait cycle. The direction of the inertial force, and therefore propulsion of the body centre of mass, was used to indicate the effect of the energy return by the energy storage and return feet. Results indicate that although energy storage and return feet may provide energy return, the work done around the prosthetic ankle indicates net power absorption. Therefore, the prosthetic limb is unable to contribute to the body centre of mass propulsion to the same extent as the biological limb. © IMechE 2014.

  5. Mass Measurement of 80Y by β-γ Coincidence Spectroscopy

    NASA Astrophysics Data System (ADS)

    Brenner, D. S.; Barton, C. J.; Zamfir, N. V.; Caprio, M. A.; Aprahamian, A.; Beausang, C. W.; Berant, Z.; Casten, R. F.; Cooper, J. R.; Gill, R. L.; Kruecken, R.; Novak, J. R.; Pietralla, N.; Shawcross, M.; Teymurazyan, A.; Wolf, A.; Wiescher, M.

    2003-06-01

    The QEC value of 80Y has been measured by β-γ coincidence spectroscopy to be ≥8929(83) keV. Combing this result with the adopted mass excess of the daughter 80Sr gives a mass excess for 80Y of ≥ -61376(83) keV. Results are compared with other measurements, with Audi-Wapstra systematics, and with predictions of mass formulas. Implications for rp-process simulations are considered.

  6. A Controlled Intervention to Promote a Healthy Body Image, Reduce Eating Disorder Risk and Prevent Excessive Exercise among Trainee Health Education and Physical Education Teachers

    ERIC Educational Resources Information Center

    Yager, Zali; O'Dea, Jennifer

    2010-01-01

    This study examined the impact of two interventions on body image, eating disorder risk and excessive exercise among 170 (65% female) trainee health education and physical education (HE & PE) teachers of mean (standard deviation) age 21.6 (2.3) who were considered an "at-risk" population for poor body image and eating disorders. In the first year…

  7. A Balanced Protocol for Return to School for Children and Youth Following Concussive Injury.

    PubMed

    DeMatteo, Carol; Stazyk, Kathy; Giglia, Lucy; Mahoney, William; Singh, Sheila K; Hollenberg, Robert; Harper, Jessica A; Missiuna, Cheryl; Law, Mary; McCauley, Dayle; Randall, Sarah

    2015-07-01

    Few protocols exist for returning children/youth to school after concussion. Childhood concussion can significantly affect school performance, which is vital to social development, academic learning, and preparation for future roles. The goal of this knowledge translation research was to develop evidence based materials to inform physicians about pediatric concussion. The Return to School (RTS) concussion protocol was developed following the National Institute for Health and Care Excellence procedures. Based on a scoping review, and stakeholder opinions, an RTS protocol was developed for children/youth. This unique protocol focuses on school adaptation in 4 main areas: (a) timetable/attendance, (b) curriculum, (c) environmental modifications, and (d) activity modifications. A balance of cognitive rest and timely return to school need to be considered for returning any student to school after a concussion. Implementation of these new recommendations may be an important tool in prevention of prolonged absence from school and academic failure while supporting brain recovery. © The Author(s) 2015.

  8. Pricing foreign equity option under stochastic volatility tempered stable Lévy processes

    NASA Astrophysics Data System (ADS)

    Gong, Xiaoli; Zhuang, Xintian

    2017-10-01

    Considering that financial assets returns exhibit leptokurtosis, asymmetry properties as well as clustering and heteroskedasticity effect, this paper substitutes the logarithm normal jumps in Heston stochastic volatility model by the classical tempered stable (CTS) distribution and normal tempered stable (NTS) distribution to construct stochastic volatility tempered stable Lévy processes (TSSV) model. The TSSV model framework permits infinite activity jump behaviors of return dynamics and time varying volatility consistently observed in financial markets through subordinating tempered stable process to stochastic volatility process, capturing leptokurtosis, fat tailedness and asymmetry features of returns. By employing the analytical characteristic function and fast Fourier transform (FFT) technique, the formula for probability density function (PDF) of TSSV returns is derived, making the analytical formula for foreign equity option (FEO) pricing available. High frequency financial returns data are employed to verify the effectiveness of proposed models in reflecting the stylized facts of financial markets. Numerical analysis is performed to investigate the relationship between the corresponding parameters and the implied volatility of foreign equity option.

  9. Pólya number and first return of bursty random walk: Rigorous solutions

    NASA Astrophysics Data System (ADS)

    Wan, J.; Xu, X. P.

    2012-03-01

    The recurrence properties of random walks can be characterized by Pólya number, i.e., the probability that the walker has returned to the origin at least once. In this paper, we investigate Pólya number and first return for bursty random walk on a line, in which the walk has different step size and moving probabilities. Using the concept of the Catalan number, we obtain exact results for first return probability, the average first return time and Pólya number for the first time. We show that Pólya number displays two different functional behavior when the walk deviates from the recurrent point. By utilizing the Lagrange inversion formula, we interpret our findings by transferring Pólya number to the closed-form solutions of an inverse function. We also calculate Pólya number using another approach, which corroborates our results and conclusions. Finally, we consider the recurrence properties and Pólya number of two variations of the bursty random walk model.

  10. Some thoughts on estimating the cost of common equity for a regulated business

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malko, J. Robert; Swensen, Philip R.; Monteleone, Joseph A.

    2007-06-15

    While mathematical models are useful in establishing a zone of reasonableness for a determination of allowed return on equity, it is important to consider the results of several models. Also key is to consider whether the analysis appropriately reflects longer-term market conditions. (author)

  11. 24 CFR 291.205 - Competitive sales of individual properties.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... considered to have been received simultaneously. HUD may use either (or both) of these methods during the bid... considered as offers from investor purchasers. (2) Noncomplying bids will be returned to the broker with an explanation for the noncompliance decision and information about whether the property is still available. (h...

  12. A hybrid genetic-simulated annealing algorithm for the location-inventory-routing problem considering returns under e-supply chain environment.

    PubMed

    Li, Yanhui; Guo, Hao; Wang, Lin; Fu, Jing

    2013-01-01

    Facility location, inventory control, and vehicle routes scheduling are critical and highly related problems in the design of logistics system for e-business. Meanwhile, the return ratio in Internet sales was significantly higher than in the traditional business. Many of returned merchandise have no quality defects, which can reenter sales channels just after a simple repackaging process. Focusing on the existing problem in e-commerce logistics system, we formulate a location-inventory-routing problem model with no quality defects returns. To solve this NP-hard problem, an effective hybrid genetic simulated annealing algorithm (HGSAA) is proposed. Results of numerical examples show that HGSAA outperforms GA on computing time, optimal solution, and computing stability. The proposed model is very useful to help managers make the right decisions under e-supply chain environment.

  13. Social capital in Asia: Investigating returns to brokerage in collectivistic national cultures.

    PubMed

    Merluzzi, Jennifer

    2013-05-01

    Evidence on the returns to brokerage networks predominately comes from studies of firms located in the United States. Analyses conducted in other countries have noted differences in how social capital may be valued questioning whether brokerage networks yield economic advantage in less individualistic contexts such as Asia. Using network data on employees involved in a product launch in the Asian region of a large American software firm, evidence of returns to brokerage is found among the top executives located and working in the collectivistic national country offices. This finding provides new insights on how returns to brokerage in a non-US culture may arise by considering the differing influences of firm and national culture as well as an employee's formal position at a firm. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Excess mortality related to the August 2003 heat wave in France

    PubMed Central

    Fouillet, Anne; Rey, Grégoire; Laurent, Françoise; Pavillon, Gérard; Bellec, Stéphanie; Ghihenneuc-Jouyaux, Chantal; Clavel, Jacqueline; Jougla, Eric; Hémon, Denis

    2006-01-01

    Objectives From August 1st to 20th, 2003, the mean maximum temperature in France exceeded the seasonal norm by 11 to 12°C on nine consecutive days. A major increase in mortality was then observed, which main epidemiological features are described herein. Methods The number of deaths observed from August to November, 2003 in France was compared to those expected on the basis of the mortality rates observed from 2000 to 2002 and the 2003 population estimates. Results From August 1st to 20th, 2003, 15000 excess deaths were observed. From 35 years age, the excess mortality was marked and increased with age. It was 15% higher in women than in men of comparable age as of age 45 years. Excess mortality at home and in retirement institutions was greater than that in hospitals. The mortality of widowed, single and divorced subjects was greater than that of married people. Deaths directly related to heat, heatstroke, hyperthermia and dehydration increased massively. Cardiovascular diseases, ill-defined morbid disorders, respiratory diseases and nervous system diseases also markedly contributed to the excess mortality. The geographic variations in mortality showed a clear age-dependent relationship with the number of very hot days. No harvesting effect was observed. Conclusions Heat waves must be considered as a threat to European populations living in climates that are currently temperate. While the elderly and people living alone are particularly vulnerable to heat waves, no segment of the population may be considered protected from the risks associated with heat waves. PMID:16523319

  15. More than Drought: Precipitation Variance, Excessive Wetness, Pathogens and the Future of the Western Edge of the Eastern Deciduous Forest.

    PubMed

    Hubbart, Jason A; Guyette, Richard; Muzika, Rose-Marie

    2016-10-01

    For many regions of the Earth, anthropogenic climate change is expected to result in increasingly divergent climate extremes. However, little is known about how increasing climate variance may affect ecosystem productivity. Forest ecosystems may be particularly susceptible to this problem considering the complex organizational structure of specialized species niche adaptations. Forest decline is often attributable to multiple stressors including prolonged heat, wildfire and insect outbreaks. These disturbances, often categorized as megadisturbances, can push temperate forests beyond sustainability thresholds. Absent from much of the contemporary forest health literature, however, is the discussion of excessive precipitation that may affect other disturbances synergistically or that might represent a principal stressor. Here, specific points of evidence are provided including historic climatology, variance predictions from global change modeling, Midwestern paleo climate data, local climate influences on net ecosystem exchange and productivity, and pathogen influences on oak mortality. Data sources reveal potential trends, deserving further investigation, indicating that the western edge of the Eastern Deciduous forest may be impacted by ongoing increased precipitation, precipitation variance and excessive wetness. Data presented, in conjunction with recent regional forest health concerns, suggest that climate variance including drought and excessive wetness should be equally considered for forest ecosystem resilience against increasingly dynamic climate. This communication serves as an alert to the need for studies on potential impacts of increasing climate variance and excessive wetness in forest ecosystem health and productivity in the Midwest US and similar forest ecosystems globally. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Cutaneous Leishmaniasis in an American Adolescent Returning From Israel.

    PubMed

    Ganjaei, Kimia G; Lawton, Kira; Gaur, Sunanda

    2018-06-06

    We present here the case of a healthy 16-year-old American girl who returned from an organized trip to Israel with cutaneous leishmaniasis caused by Leishmania major; the infection was treated successfully with paromomycin-gentamicin ointment. She was initially misdiagnosed with staphylococcal and pseudomonal cellulitis. Although cutaneous leishmaniasis is seen only rarely in the United States, it should be considered when diagnosing new skin lesions after travel to affected countries.

  17. Impact of lunar oxygen production on direct manned Mars missions

    NASA Technical Reports Server (NTRS)

    Young, Roy M., Jr.; Tucker, William B.

    1992-01-01

    A manned Mars program made up of six missions is evaluated to determine the impact of using lunar liquid oxygen (LOX) as a propellant. Two departure and return nodes, low Earth orbit and low lunar orbit, are considered, as well as two return vehicle configurations, a full 70,000-kg vehicle and a 6800-kg capsule. The cost of lunar LOX delivered to orbit is expressed as a ratio of Earth launch cost.

  18. Advanced Numerical Methods for Computing Statistical Quantities of Interest from Solutions of SPDES

    DTIC Science & Technology

    2012-01-19

    and related optimization problems; developing numerical methods for option pricing problems in the presence of random arbitrage return. 1. Novel...equations (BSDEs) are connected to nonlinear partial differen- tial equations and non-linear semigroups, to the theory of hedging and pricing of contingent...the presence of random arbitrage return [3] We consider option pricing problems when we relax the condition of no arbitrage in the Black- Scholes

  19. Tularaemia in Berlin - two independent cases in travellers returning from central Anatolia, Turkey, February 2011.

    PubMed

    Schubert, A; Splettstoesser, W; Bätzing-Feigenbaum, J

    2011-05-05

    Tularaemia, though rare, has recently been increasingly reported in Germany. Most cases are indigenous infections. This report describes two epidemiologically independent infections with Francisella tularensis subspecies holarctica detected in Berlin in February 2011 that were acquired in central Anatolia, Turkey. In Turkey, there have been repeated tularaemia outbreaks since 2000 and the disease should therefore be considered as a differential diagnosis in travellers returning from that country.

  20. A hard X-ray view of the soft excess in AGN

    NASA Astrophysics Data System (ADS)

    Boissay, R.; Ricci, C.; Paltani, S.

    2017-10-01

    A soft X-ray emission in excess of the extrapolation of the hard X-ray continuum is detected in many Seyfert 1 galaxies below 1 keV. To understand the uncertain nature of this soft excess, which could be due to warm Comptonization or to blurred ionized reflection, we consider the different behaviors of these models above 10 keV. We present the results of a study done on 102 Seyfert 1s from the Swift BAT 70-Month Hard X-ray Survey catalog. We have performed the joint spectral analysis of Swift/BAT and XMM-Newton data in order to get a hard X-ray view of the soft excess. We discuss the links between the soft-excess strength and the reflection at high energy, the slope of the continuum and the Eddington ratio. We compare our results to simulations of blurred ionized-reflection models and show that they are in contradiction. Indeed, we do not find the expected correlation between the reflection and the soft-excess strengths, neither in individual, nor in stacked spectra. We also present our current project of broadband fitting, using different models explaining the soft excess, to simultaneous XMM-Newton and NuSTAR observations of about ten objects of our sample.

  1. Reduction of excess sludge in a sequencing batch reactor by lysis-cryptic growth using quick lime for disintegration under low temperature.

    PubMed

    Lv, Xiao-Mei; Song, Ju-Sheng; Li, Ji; Zhai, Kun

    2017-08-01

    In the present study, quick-lime-based thermal-alkaline sludge disintegration (SD) under low temperature was combined with cryptic growth to investigate the excess sludge reduction efficiency in the sequencing batch reactor (SBR). The optimized condition of SD was as follows: T = 80℃, pH = 11, t = 180 min, and the SD rate was about 42.1%. With 65.6% of excess sludge disintegrated and returned to the SBR, the system achieved sludge reduction rate of about 40.1%. The lysis-cryptic growth still obtained satisfactory sludge reduction efficiency despite the comparative low SD rate, which suggested that disintegration rate might not be the decisive factor for cryptic-growth-based sludge reduction. Lysis-cryptic growth did not impact the effluent quality, yet the phosphorus removal performance was enhanced, with effluent total phosphorus concentration decreased by 0.3 mg/L (33%). Crystal compounds of calcium phosphate precipitate were detected in the system by Fourier transform infrared spectroscopy and X-ray diffraction, which indicated the phosphorus removal potential of SD using lime. Moreover, endogenous dehydrogenase activity of activated sludge in the lysis-cryptic system was enhanced, which was beneficial for sludge reduction. SD and cryptic growth in the present study demonstrates an economical and effective approach for sludge reduction.

  2. Rapid Recovery Gene Downregulation during Excess-Light Stress and Recovery in Arabidopsis.

    PubMed

    Crisp, Peter A; Ganguly, Diep R; Smith, Aaron B; Murray, Kevin D; Estavillo, Gonzalo M; Searle, Iain; Ford, Ethan; Bogdanović, Ozren; Lister, Ryan; Borevitz, Justin O; Eichten, Steven R; Pogson, Barry J

    2017-08-01

    Stress recovery may prove to be a promising approach to increase plant performance and, theoretically, mRNA instability may facilitate faster recovery. Transcriptome (RNA-seq, qPCR, sRNA-seq, and PARE) and methylome profiling during repeated excess-light stress and recovery was performed at intervals as short as 3 min. We demonstrate that 87% of the stress-upregulated mRNAs analyzed exhibit very rapid recovery. For instance, HSP101 abundance declined 2-fold every 5.1 min. We term this phenomenon rapid recovery gene downregulation (RRGD), whereby mRNA abundance rapidly decreases promoting transcriptome resetting. Decay constants ( k ) were modeled using two strategies, linear and nonlinear least squares regressions, with the latter accounting for both transcription and degradation. This revealed extremely short half-lives ranging from 2.7 to 60.0 min for 222 genes. Ribosome footprinting using degradome data demonstrated RRGD loci undergo cotranslational decay and identified changes in the ribosome stalling index during stress and recovery. However, small RNAs and 5'-3' RNA decay were not essential for recovery of the transcripts examined, nor were any of the six excess light-associated methylome changes. We observed recovery-specific gene expression networks upon return to favorable conditions and six transcriptional memory types. In summary, rapid transcriptome resetting is reported in the context of active recovery and cellular memory. © 2017 American Society of Plant Biologists. All rights reserved.

  3. Rapid Recovery Gene Downregulation during Excess-Light Stress and Recovery in Arabidopsis[OPEN

    PubMed Central

    Estavillo, Gonzalo M.

    2017-01-01

    Stress recovery may prove to be a promising approach to increase plant performance and, theoretically, mRNA instability may facilitate faster recovery. Transcriptome (RNA-seq, qPCR, sRNA-seq, and PARE) and methylome profiling during repeated excess-light stress and recovery was performed at intervals as short as 3 min. We demonstrate that 87% of the stress-upregulated mRNAs analyzed exhibit very rapid recovery. For instance, HSP101 abundance declined 2-fold every 5.1 min. We term this phenomenon rapid recovery gene downregulation (RRGD), whereby mRNA abundance rapidly decreases promoting transcriptome resetting. Decay constants (k) were modeled using two strategies, linear and nonlinear least squares regressions, with the latter accounting for both transcription and degradation. This revealed extremely short half-lives ranging from 2.7 to 60.0 min for 222 genes. Ribosome footprinting using degradome data demonstrated RRGD loci undergo cotranslational decay and identified changes in the ribosome stalling index during stress and recovery. However, small RNAs and 5ʹ-3ʹ RNA decay were not essential for recovery of the transcripts examined, nor were any of the six excess light-associated methylome changes. We observed recovery-specific gene expression networks upon return to favorable conditions and six transcriptional memory types. In summary, rapid transcriptome resetting is reported in the context of active recovery and cellular memory. PMID:28705956

  4. Association between workaholism and sleep problems among hospital nurses.

    PubMed

    Kubota, Kazumi; Shimazu, Akihito; Kawakami, Norito; Takahashi, Masaya; Nakata, Akinori; Schaufeli, Wilmar B

    2010-01-01

    The present study examined the association between workaholism, the tendency to work excessively hard in a compulsive fashion, and sleep problems among Japanese nurses. A cross-sectional survey was conducted among 600 nurses from 2 university hospitals in Japan using a self-reported questionnaire on workaholism, sleep, job-related variables (i.e., job demands, job control, and worksite support), and demographic variables. A total of 394 nurses returned the questionnaire (response rate=65.7%) and complete data from 312 female nurses were used for analyses (final coverage rate=52.0%). Workaholics, as measured using the Japanese version of the Dutch Workaholism Scale, were defined as those having high scores on both the "work excessively" and "work compulsively" subscales. Logistic regression analyses revealed that workaholics had higher risks for sleep problems in terms of subjective sleep insufficiency, excessive daytime sleepiness at work, difficulty awakening in the morning, and feeling tired when waking up in the morning (odds ratios [OR] of 4.40, 3.18, 3.48, and 4.61, respectively, p<0.05). These remained significant even after adjusting for demographic and job-related variables (OR 3.41, 5.36, 2.56, and 2.77, respectively). However, no significant associations were found between workaholism and insomnia symptoms. These results suggest that workaholic nurses had higher risks for impaired awakening, insufficient sleep, and workplace sleepiness.

  5. Treatment of peroneal nerve injuries with simultaneous tendon transfer and nerve exploration.

    PubMed

    Ho, Bryant; Khan, Zubair; Switaj, Paul J; Ochenjele, George; Fuchs, Daniel; Dahl, William; Cederna, Paul; Kung, Theodore A; Kadakia, Anish R

    2014-08-06

    Common peroneal nerve palsy leading to foot drop is difficult to manage and has historically been treated with extended bracing with expectant waiting for return of nerve function. Peroneal nerve exploration has traditionally been avoided except in cases of known traumatic or iatrogenic injury, with tendon transfers being performed in a delayed fashion after exhausting conservative treatment. We present a new strategy for management of foot drop with nerve exploration and concomitant tendon transfer. We retrospectively reviewed a series of 12 patients with peroneal nerve palsies that were treated with tendon transfer from 2005 to 2011. Of these patients, seven were treated with simultaneous peroneal nerve exploration and repair at the time of tendon transfer. Patients with both nerve repair and tendon transfer had superior functional results with active dorsiflexion in all patients, compared to dorsiflexion in 40% of patients treated with tendon transfers alone. Additionally, 57% of patients treated with nerve repair and tendon transfer were able to achieve enough function to return to running, compared to 20% in patients with tendon transfer alone. No patient had full return of native motor function resulting in excessive dorsiflexion strength. The results of our limited case series for this rare condition indicate that simultaneous nerve repair and tendon transfer showed no detrimental results and may provide improved function over tendon transfer alone.

  6. Six-Month Market Exclusivity Extensions To Promote Research Offer Substantial Returns For Many Drug Makers.

    PubMed

    Kesselheim, Aaron S; Rome, Benjamin N; Sarpatwari, Ameet; Avorn, Jerry

    2017-02-01

    To incentivize pharmaceutical manufacturers to invest in areas of unmet medical need, policy makers frequently propose extending the market exclusivity period of desired drugs. Some such proposals are modeled after the pediatric exclusivity patent extension program, which since 1997 has provided six additional months of market exclusivity for drugs studied in children. The most recent proposal would encourage rare disease research by providing six months of extended exclusivity for any existing drug that is granted subsequent FDA approval for a new rare disease indication. Yet the economic impact of such proposals is rarely addressed. We found that for the thirteen FDA-approved drugs that gained supplemental approval for a rare disease indication from 2005 through 2010, the median projected cost of clinical trials leading to approval was $29.8 million. If the exclusivity extension had been in place, the median discounted financial gain to manufacturers would have been $94.6 million. Median net returns would have been $82.4 million, with higher returns for drugs with higher annual sales. Extending market exclusivity would provide substantial compensation to many manufacturers, particularly for top-selling products, far in excess of the cost of conducting these trials. Alternative strategies to incentivize the study of approved drugs for rare diseases may offer similar benefits at a lower cost. Project HOPE—The People-to-People Health Foundation, Inc.

  7. The prevalence of quality issues and adverse outcomes among 72-hour return admissions in the emergency department.

    PubMed

    Abualenain, Jameel; Frohna, William J; Smith, Mark; Pipkin, Michael; Webb, Cynthia; Milzman, David; Pines, Jesse M

    2013-08-01

    Records of patients discharged from the Emergency Department (ED) who return within 72 h and are admitted are often reviewed for potential quality issues. We explored 72-h return admissions and determined the prevalence and predictors for substandard management on the initial visit or any adverse outcome. Retrospective review of quality assurance data from 72-h return admissions in three hospitals from 2006-2010 was performed. Any substandard quality on the first visit or change in outcome on the return admission was considered "low quality." Multivariate logistic regression was used to assess the relationship between cases judged as low quality vs. not low quality. Of 741,132 ED visits across 5 years, 3682 (0.5%) were 72-h return admissions. Of those, 192 (5%) were low quality. In 158 (4%) and 8 (0.2%) there were moderate and severe deviations from care standards, respectively. Similarly, in 53 (1%) and 14 (0.4%) there were moderate and severe changes in outcome. In adjusted analysis, there were higher rates of low-quality 72-h return admissions in ambulance arrivals (odds ratio [OR] 1.5, 95% confidence interval (CI) 1.1-2.1); and lower rates in Medicaid patients (OR 0.3, 95% CI 0.2-0.7). There were higher rates in low-quality 72-h return admissions in hospital 1 (OR 3.6, 95% CI 2.2-6.1) and hospital 3 (OR 3.2, 95% CI 2.0-4.7) compared to hospital 2. Poor care on the initial visit or any poor outcome upon returning in 72-h return admissions is relatively rare in the ED. Reporting 72-h return admissions without chart review may not be a good way to measure clinical quality. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. The role of job strain on return to work after carpal tunnel surgery

    PubMed Central

    Gimeno, D; Amick, B; Habeck, R; Ossmann, J; Katz, J

    2005-01-01

    Aims: To examine the impact of job strain (that is, high psychological job demands and low job control) on return to work and work role functioning at two months, six months, or both, following carpal tunnel release surgery. Methods: A community based cohort of carpal tunnel syndrome (CTS) patients from physician practices was recruited between April 1997 and October 1998 throughout Maine (USA). 128 patients at two months and 122 at six months completed all relevant questions. A three level outcome variable indicated whether patients had: (1) returned to work functioning successfully, (2) returned to work functioning with limitations, or (3) not returned to work for health reasons. Two job strain measures were created: one, by combining psychological job demands and job control; and two, by dividing demands by control. Ordinal logistic regression was used to identify predictors of the three level work outcome variable. Results: After adjustment, workers with high demands and high control (active work) were less likely to successfully return to work (OR = 0.22; p = 0.014) at two months. Having a job with higher demands than job control (high strain) predicted not returning to work or returning to work but not successfully meeting job demands (OR = 0.14; p = 0.001), at six months. Conclusions: The findings underscore the role of psychosocial work conditions, as defined by the Karasek demand-control model, in explaining a worker's return to work. Clinicians, researchers, and employers should consider a multidimensional and integrative model of successful work role functioning upon return to work. Moreover, since the evidence of the effects of work process changes on the reduction of CTS is very scarce, these findings point to the opportunity for collaborative workplace interventions to facilitate successful return to work. PMID:16234404

  9. Communication and collaboration among return-to-work stakeholders.

    PubMed

    Russell, Elizabeth; Kosny, Agnieszka

    2018-05-17

    Workers who are injured or become ill on the job are best able to return-to-work when stakeholders involved in their case collaborate and communicate. This study examined health care providers' and case managers' engagement in rehabilitation and return-to-work following workplace injury or illness. In-depth interviews were conducted with 97 health care providers and 34 case managers in four Canadian provinces about their experiences facilitating rehabilitation and return-to-work, and interacting with system stakeholders. A qualitative thematic content analysis demonstrated two key findings. Firstly, stakeholders were challenged to collaborate as a result of: barriers to interdisciplinary and cross-professional communication; philosophical differences about the timing and appropriateness of return-to-work; and confusion among health care providers about the workers' compensation system. Secondly, these challenges adversely affected the co-ordination of patient care, and consequentially, injured workers often became information conduits, and effective and timely treatment and return-to-work was sometimes negatively impacted. Communication challenges between health care providers and case managers may negatively impact patient care and alienate treating health care providers. Discussion about role clarification, the appropriateness of early return-to-work, how paperwork shapes health care providers' role expectations, and strengthened inter-professional communication are considered. Implications for Rehabilitation Administrative and conceptual barriers in workers' compensation systems challenge collaboration and communication between health care providers and case managers. Injured workers may become conduits of incorrect information, resulting in adversarial relationships, overturned health care providers' recommendations, and their disengagement from rehabilitation and return-to-work. Stakeholders should clarify the role of health care providers during rehabilitation and return-to-work and the appropriateness of early return-to-work to mitigate recurring challenges. Communication procedures between health care specialists may disrupt these challenges, increasing the likelihood of timely and effective rehabilitation and return-to-work.

  10. Trend analysis for daily rainfall series of Barcelona

    NASA Astrophysics Data System (ADS)

    Ortego, M. I.; Gibergans-Báguena, J.; Tolosana-Delgado, R.; Egozcue, J. J.; Llasat, M. C.

    2009-09-01

    Frequency analysis of hydrological series is a key point to acquire an in-depth understanding of the behaviour of hydrologic events. The occurrence of extreme hydrologic events in an area may imply great social and economical impacts. A good understanding of hazardous events improves the planning of human activities. A useful model for hazard assessment of extreme hydrologic events in an area is the point-over-threshold (POT) model. Time-occurrence of events is assumed to be Poisson distributed, and the magnitude X of each event is modeled as an arbitrary random variable, whose excesses over the threshold x0, Y = X - x0, given X > x0, have a Generalized Pareto Distribution (GPD), ( ? )- 1? FY (y|β,?) = 1 - 1+ βy , 0 ? y < ysup , where ysup = +? if ? 0, and ysup = -β? ? if ? < 0. The limiting distribution for ? = 0 is an exponential one. Independence between this magnitude and occurrence in time is assumed, as well as independence from event to event. In order to take account for uncertainty of the estimation of the GPD parameters, a Bayesian approach is chosen. This approach allows to include necessary conditions on the parameters of the distribution for our particular phenomena, as well as propagate adequately the uncertainty of estimations to the hazard parameters, such as return periods. A common concern is to know whether magnitudes of hazardous events have changed in the last decades. Long data series are very appreciated in order to properly study these issues. The series of daily rainfall in Barcelona (1854-2006) has been selected. This is one of the longer european daily rainfall series available. Daily rainfall is better described using a relative scale and therefore it is suitably treated in a log-scale. Accordingly, log-precipitation is identified with X. Excesses over a threshold are modeled by a GPD with a limited maximum value. An additional assumption is that the distribution of the excesses Y has limited upper tail and, therefore, ? < 0, ysup = -β?. Such a long data series provides valuable information about the phenomena on hand, and therefore a very first step is to have a look to its reliability. The first part of the work focuses on the possible existence of abrupt changes in the parameters of the GPD. These abrupt changes may be due to changes in the location of the observatories and/or technological advances introduced in the measuring instruments. The second part of the work examines the possible existence of trends. The parameters of the model are considered as a function of time. A new parameterisation of the GPD distribution is suggested, in order to parsimoniously deal with this climate variation, ? = ln(-? ?;β) and ? = ln(-? ? β) The classical scale and shape parameters of the GPD (β,?) are reformulated as a location parameter ? "linked to the upper limit of the distribution", and a shape parameter ?. In this reparameterisation, the parsimonious choice is to consider shape as a linear function of time, ?(t) = ?0 + t? while keeping location fixed, ?(t) = ?0. Then, the climate change is assessed by checking the hypothesis ? 0. Results show no significant abrupt changes in excesses distribution of the Barcelona daily rainfall series but suggest a significant change for the parameters, and therefore the existence of a trend in daily rainfall for this period.

  11. Mass measurement of 80Y by β-γ coincidence spectroscopy

    NASA Astrophysics Data System (ADS)

    Barton, C. J.; Brenner, D. S.; Zamfir, N. V.; Caprio, M. A.; Aprahamian, A.; Wiescher, M. C.; Beausang, C. W.; Berant, Z.; Casten, R. F.; Cooper, J. R.; Gill, R. L.; Krücken, R.; Novak, J. R.; Pietralla, N.; Shawcross, M.; Teymurazyan, A.; Wolf, A.

    2003-03-01

    The QEC value of 80Y has been measured by β-γ coincidence spectroscopy to be ⩾8929(83) keV. Combining this result with the adopted mass excess of the daughter 80Sr gives a mass excess for 80Y of ⩾-61 376(83) keV. Results are compared with other measurements, with Audi-Wapstra systematics, and with predictions of mass formulas. Implications of this measurement are considered for the rp process.

  12. Passive vs. Parachute System Architecture for Robotic Sample Return Vehicles

    NASA Technical Reports Server (NTRS)

    Maddock, Robert W.; Henning, Allen B.; Samareh, Jamshid A.

    2016-01-01

    The Multi-Mission Earth Entry Vehicle (MMEEV) is a flexible vehicle concept based on the Mars Sample Return (MSR) EEV design which can be used in the preliminary sample return mission study phase to parametrically investigate any trade space of interest to determine the best entry vehicle design approach for that particular mission concept. In addition to the trade space dimensions often considered (e.g. entry conditions, payload size and mass, vehicle size, etc.), the MMEEV trade space considers whether it might be more beneficial for the vehicle to utilize a parachute system during descent/landing or to be fully passive (i.e. not use a parachute). In order to evaluate this trade space dimension, a simplified parachute system model has been developed based on inputs such as vehicle size/mass, payload size/mass and landing requirements. This model works in conjunction with analytical approximations of a mission trade space dataset provided by the MMEEV System Analysis for Planetary EDL (M-SAPE) tool to help quantify the differences between an active (with parachute) and a passive (no parachute) vehicle concept.

  13. Linear versus quadratic portfolio optimization model with transaction cost

    NASA Astrophysics Data System (ADS)

    Razak, Norhidayah Bt Ab; Kamil, Karmila Hanim; Elias, Siti Masitah

    2014-06-01

    Optimization model is introduced to become one of the decision making tools in investment. Hence, it is always a big challenge for investors to select the best model that could fulfill their goal in investment with respect to risk and return. In this paper we aims to discuss and compare the portfolio allocation and performance generated by quadratic and linear portfolio optimization models namely of Markowitz and Maximin model respectively. The application of these models has been proven to be significant and popular among others. However transaction cost has been debated as one of the important aspects that should be considered for portfolio reallocation as portfolio return could be significantly reduced when transaction cost is taken into consideration. Therefore, recognizing the importance to consider transaction cost value when calculating portfolio' return, we formulate this paper by using data from Shariah compliant securities listed in Bursa Malaysia. It is expected that, results from this paper will effectively justify the advantage of one model to another and shed some lights in quest to find the best decision making tools in investment for individual investors.

  14. Quantum return probability of a system of N non-interacting lattice fermions

    NASA Astrophysics Data System (ADS)

    Krapivsky, P. L.; Luck, J. M.; Mallick, K.

    2018-02-01

    We consider N non-interacting fermions performing continuous-time quantum walks on a one-dimensional lattice. The system is launched from a most compact configuration where the fermions occupy neighboring sites. We calculate exactly the quantum return probability (sometimes referred to as the Loschmidt echo) of observing the very same compact state at a later time t. Remarkably, this probability depends on the parity of the fermion number—it decays as a power of time for even N, while for odd N it exhibits periodic oscillations modulated by a decaying power law. The exponent also slightly depends on the parity of N, and is roughly twice smaller than what it would be in the continuum limit. We also consider the same problem, and obtain similar results, in the presence of an impenetrable wall at the origin constraining the particles to remain on the positive half-line. We derive closed-form expressions for the amplitudes of the power-law decay of the return probability in all cases. The key point in the derivation is the use of Mehta integrals, which are limiting cases of the Selberg integral.

  15. Resonant slepton production yields CMS e e j j and e p Tj j excesses

    NASA Astrophysics Data System (ADS)

    Allanach, Ben; Biswas, Sanjoy; Mondal, Subhadeep; Mitra, Manimala

    2015-01-01

    Recent CMS searches for dileptoquark production report local excesses of 2.4 σ in an e e j j channel and 2.6 σ in an e p Tj j channel. Here, we simultaneously explain both excesses with resonant slepton production in R -parity violating supersymmetry. We consider resonant slepton production, which decays to a lepton and a chargino/neutralino, followed by three-body decays of the neutralino/chargino via an R -parity violating coupling. There are regions of parameter space which are also compatible at the 95% confidence level with a 2.8 σ e e j j excess in a recent CMS WR search, while being compatible with other direct search constraints. Phase II of the GERDA neutrinoless double beta decay (0 ν β β ) experiment will probe a sizable portion of the good-fit region.

  16. Long-term health experience of jet engine manufacturing workers: IX. further investigation of general mortality patterns in relation to workplace exposures.

    PubMed

    Youk, Ada O; Marsh, Gary M; Buchanich, Jeanine M; Downing, Sarah; Kennedy, Kathleen J; Esmen, Nurtan A; Hancock, Roger P; Lacey, Steven E

    2013-06-01

    To evaluate mortality rates among a cohort of jet engine manufacturing workers. Subjects were 222,123 workers employed from 1952 to 2001. Vital status was determined through 2004 for 99% of subjects and cause of death for 95% of 68,317 deaths. We computed standardized mortality ratios and modeled internal cohort rates. Mortality excesses reported initially no longer met the criteria for further investigation. We found two chronic obstructive pulmonary disease-related mortality excesses that met the criteria in two of eight study plants. At the total cohort level, chronic obstructive pulmonary disease-related categories were not related to any factors or occupational exposures considered. A full evaluation of these excesses was limited by lack of data on smoking history. Occupational exposures received outside of work or uncontrolled positive confounding by smoking cannot be ruled out as reasons for these excesses.

  17. Hα Variability in PTFO8-8695 and the Possible Direct Detection of Emission from a 2 Million Year Old Evaporating Hot Jupiter

    NASA Astrophysics Data System (ADS)

    Johns-Krull, Christopher M.; Prato, Lisa; McLane, Jacob N.; Ciardi, David R.; van Eyken, Julian C.; Chen, Wei; Stauffer, John R.; Beichman, Charles A.; Frazier, Sarah A.; Boden, Andrew F.; Morales-Calderón, Maria; Rebull, Luisa M.

    2016-10-01

    We use high time cadence, high spectral resolution optical observations to detect excess Hα emission from the 2-3 Myr old weak-lined T Tauri star PTFO 8-8695. This excess emission appears to move in velocity as expected if it were produced by the suspected planetary companion to this young star. The excess emission is not always present, but when it is, the predicted velocity motion is often observed. We have considered the possibility that the observed excess emission is produced by stellar activity (flares), accretion from a disk, or a planetary companion; we find the planetary companion to be the most likely explanation. If this is the case, the strength of the Hα line indicates that the emission comes from an extended volume around the planet, likely fed by mass loss from the planet which is expected to be overflowing its Roche lobe.

  18. An update on the LHC monojet excess

    NASA Astrophysics Data System (ADS)

    Asadi, Pouya; Buckley, Matthew R.; DiFranzo, Anthony; Monteux, Angelo; Shih, David

    2018-03-01

    In previous work, we identified an anomalous number of events in the LHC jets+MET searches characterized by low jet multiplicity and low-to-moderate transverse energy variables. Here, we update this analysis with results from a new ATLAS search in the monojet channel which also shows a consistent excess. As before, we find that this "monojet excess" is well-described by the resonant production of a heavy colored state decaying to a quark and a massive invisible particle. In the combined ATLAS and CMS data, we now find a local (global) preference of 3.3 σ (2.5 σ) for the new physics model over the Standard Model-only hypothesis. As the signal regions containing the excess are systematics-limited, we consider additional cuts to enhance the signal-to-background ratio. We show that binning finer in H T and requiring the jets to be more central can increase S/B by a factor of ˜1 .5.

  19. Variety of Behavior of Equity Returns in Financial Markets

    NASA Astrophysics Data System (ADS)

    Bonanno, Giovanni; Lillo, Fabrizio; Mantegna, Rosario N.

    2001-03-01

    The price dynamics of a set of equities traded in an efficient market is pretty complex. It consists of almost not redundant time series which have (i) long-range correlated volatility and (ii) cross-correlation between each pair of equities. We perform a study of the statistical properties of an ensemble of equities returns which is fruitful to elucidate the nature and role of time and ensemble correlation. Specifically, we investigate a statistical ensemble of daily returns of n equities traded in United States financial markets. For each trading day of our database, we study the ensemble return distribution. We find that a typical ensemble return distribution exists in most of the trading days [1] with the exception of crash and rally days and of the days following to these extreme events [2]. We analyze each ensemble return distribution by extracting its first two central moments. We call the second moment of the ensemble return distribution the variety of the market. We choose this term because high variety implies a variated behavior of the equities returns in the considered day. We observe that the mean return and the variety are fluctuating in time and are stochastic processes themselves. The variety is a long-range correlated stochastic process. Customary time-averaged statistical properties of time series of stock returns are also considered. In general, time-averaged and portfolio-averaged returns have different statistical properties [1]. We infer from these differences information about the relative strength of correlation between equities and between different trading days. We also compare our empirical results with those predicted by the single-index model and we conclude that this simple model is unable to explain the statistical properties of the second moment of the ensemble return distribution. Correlation between pairs of equities are continuously present in the dynamics of a stock portfolio. Hence, it is relevant to investigate pair correlation in a efficient and original way. We propose to investigate these correlations at a daily and intra daily time horizon with a method based on concepts of random frustrated systems. Specifically, a hierarchical organization of the investigated equities is obtained by determining a metric distance between stocks and by investigating the properties of the subdominant ultrametric associated with it [3]. The high-frequency cross-correlation existing between pairs of equities are investigated in a set of 100 stocks traded in US equity markets. The decrease of the cross-correlation between the equity returns observed for diminishing time horizons progressively changes the nature of the hierarchical structure associated to each different time horizon [4]. The nature of the correlation present between pairs of time series of equity returns collected in a portfolio has a strong influence on the variety of the market. We finally discuss the relation between pair correlation and variety of an ensemble return distribution. References [1] Fabrizio Lillo and Rosario N. Mantegna, Variety and volatility in financial markets, Phys. Rev. E 62, 6126-6134 (2000). [2] Fabrizio Lillo and Rosario N. Mantegna, Symmetry alteration of ensemble return distribution in crash and rally days of financial market, Eur. Phys. J. B 15, 603-606 (2000). [3] Rosario N. Mantegna, Hierarchical structure in financial markets, Eur. Phys. J. B 11, 193-197 (1999). [4] Giovanni Bonanno, Fabrizio Lillo, and Rosario N. Mantegna, High-frequency cross-correlation in a set of stocks, Quantitative Finance (in press).

  20. The 22-Modifier in Reimbursement for Orthopedic Procedures: Hip Arthroplasty and Obesity Are Worth the Effort.

    PubMed

    Smith, Eric L; Tybor, David J; Daniell, Hayley D; Naccarato, Laura A; Pevear, Mary E; Cassidy, Charles

    2018-02-21

    Orthopedic surgeons utilize the 22-modifier when billing for complex procedures under the American Medical Association's Current Procedural Terminology (CPT) for reasons such as excessive blood loss, anatomic abnormality, and morbid obesity, cases that would ideally be reimbursed at a higher rate to compensate for additional physician work and time. We investigated how the 22-modifier affects physician reimbursement in knee and hip arthroplasty. We queried hospital billing data from 2009 to 2016, identifying all cases performed at our urban tertiary care orthopedic center for knee arthroplasty (CPT codes 27438, 27447, 27487, and 27488) and hip arthroplasty (CPT codes 27130, 27132, 27134, 27236). We extracted patient insurance status and reimbursement data to compare the average reimbursement between cases with and without the 22-modifier. We analyzed data from 2605 procedures performed by 10 providers. There were 136 cases with 22-modifiers. For knee arthroplasty (n = 1323), the 22-modifier did not significantly increase reimbursement after adjusting for insurer, provider, and fiscal year (4.2% dollars higher on average, P = .159). For hip arthroplasty (n = 1282), cases with a 22-modifier had significantly higher reimbursement than those without the 22-modifier (6.2% dollars more, P = .049). For hip arthroplasty cases with a 22-modifier, those noting morbid obesity were reimbursed 29% higher than those cases with other etiology. The effect of the 22-modifier on reimbursement amount is differential between knee and hip arthroplasty. Hip arthroplasty procedures coded as 22-modifier are reimbursed more than those without the 22-modifier. Providers should consider these potential returns when considering submitting a 22-modifier. Copyright © 2018 Elsevier Inc. All rights reserved.

  1. Static vs stochastic optimization: A case study of FTSE Bursa Malaysia sectorial indices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mamat, Nur Jumaadzan Zaleha; Jaaman, Saiful Hafizah; Ahmad, Rokiah Rozita

    2014-06-19

    Traditional portfolio optimization methods in the likes of Markowitz' mean-variance model and semi-variance model utilize static expected return and volatility risk from historical data to generate an optimal portfolio. The optimal portfolio may not truly be optimal in reality due to the fact that maximum and minimum values from the data may largely influence the expected return and volatility risk values. This paper considers distributions of assets' return and volatility risk to determine a more realistic optimized portfolio. For illustration purposes, the sectorial indices data in FTSE Bursa Malaysia is employed. The results show that stochastic optimization provides more stablemore » information ratio.« less

  2. Tracking and Data Relay Satellite System (TDRSS) Support of User Spacecraft without TDRSS Transponders

    NASA Technical Reports Server (NTRS)

    Jackson, James A.; Marr, Greg C.; Maher, Michael J.

    1995-01-01

    NASA GSFC VNS TSG personnel have proposed the use of TDRSS to obtain telemetry and/or S-band one-way return Doppler tracking data for spacecraft which do not have TDRSS-compatible transponders and therefore were never considered candidates for TDRSS support. For spacecraft with less stable local oscillators (LO), one-way return Doppler tracking data is typically of poor quality. It has been demonstrated using UARS, WIND, and NOAA-J tracking data that the simultaneous use of two TDRSS spacecraft can yield differenced one-way return Doppler data of high quality which is usable for orbit determination by differencing away the effects of oscillator instability.

  3. Micronized coal burner facility

    NASA Technical Reports Server (NTRS)

    Calfo, F. D.; Lupton, M. W. (Inventor)

    1984-01-01

    A combustor or burner system in which the ash resulting from burning a coal in oil mixture is of submicron particle size is described. The burner system comprises a burner section, a flame exit nozzle, a fuel nozzle section, and an air tube by which preheated air is directed into the burner section. Regulated air pressure is delivered to a fuel nozzle. Means are provided for directing a mixture of coal particles and oil from a drum to a nozzle at a desired rate and pressure while means returns excess fuel to the fuel drum. Means provide for stable fuel pressure supply from the fuel pump to the fuel nozzle.

  4. Pituitary gigantism causing diabetic ketoacidosis.

    PubMed

    Alvi, N S; Kirk, J M

    1999-01-01

    Although growth hormone excess (acromegaly) in association with glucose intolerance and diabetes mellitus is well documented in adult medicine, it is much less common in the paediatric age group. We report the case of a 13 year-old boy who presented with tall stature secondary to a large growth hormone secreting adenoma of the pituitary gland. Random growth hormone was 630 mIU/l and did not suppress during an oral glucose tolerance test. Following debulking of the tumour, he developed diabetic ketoacidosis requiring insulin treatment, but after further surgery glucose handling returned to normal. He has been started on testosterone to arrest further increase in height.

  5. Solar powered actuator with continuously variable auxiliary power control

    NASA Technical Reports Server (NTRS)

    Nola, F. J. (Inventor)

    1984-01-01

    A solar powered system is disclosed in which a load such as a compressor is driven by a main induction motor powered by a solar array. An auxiliary motor shares the load with the solar powered motor in proportion to the amount of sunlight available, is provided with a power factor controller for controlling voltage applied to the auxiliary motor in accordance with the loading on that motor. In one embodiment, when sufficient power is available from the solar cell, the auxiliary motor is driven as a generator by excess power from the main motor so as to return electrical energy to the power company utility lines.

  6. Down-flow moving-bed gasifier with catalyst recycle

    DOEpatents

    Halow, John S.

    1999-01-01

    The gasification of coal and other carbonaceous materials by an endothermic gasification reaction is achieved in the presence of a catalyst in a down-flow, moving-bed gasifier. Catalyst is removed along with ash from the gasifier and is then sufficiently heated in a riser/burner by the combustion of residual carbon in the ash to volatilize the catalyst. This volatilized catalyst is returned to the gasifier where it uniformly contacts and condenses on the carbonaceous material. Also, the hot gaseous combustion products resulting from the combustion of the carbon in the ash along with excess air are introduced into the gasifier for providing heat energy used in the endothermic reaction.

  7. Beyond Educational Tourism: Lessons Learned while Student Teaching Abroad

    ERIC Educational Resources Information Center

    Quezada, Reyes L.

    2004-01-01

    Many universities provide overseas student teaching yet little is known as to what knowledge, skills, and dispositions university students have prior to arriving in their host country as well as after their return to their home country. This article considers several key issues and suggests factors that schools of education should consider when…

  8. Reading Canonical Texts in Multicultural Classrooms

    ERIC Educational Resources Information Center

    Shah, Mehrunissa

    2013-01-01

    This essay explores the complexity of imposing texts that are considered part of the English literary canon on students from multicultural backgrounds. It considers the rhetoric of the coalition government, in the recent drive to emphasize the importance of the literary heritage and return to English culture and how its impact has been felt in the…

  9. [Return to Work Strategies of Employees who Experienced Depression: Employers and HR's Perspectives].

    PubMed

    Corbière, Marc; Lecomte, Tania; Lachance, Jean-Philippe; Coutu, Marie-France; Negrini, Alessia; Laberon, Sonia

    Major depression is one of the leading causes of work disability across the world. In Canada, the lifetime prevalence of depression varies from 10 to 12%. Depression impacts not only the employee who is often stigmatized and can lose his professional identity, but also has consequences on colleagues and supervisors in organizations. In the literature, four models are described from which employers and managers use in their organizations to make decisions regarding the work disability of employees on sick leave: biomedical, financial management, personnel management, and organizational development. These models can also be supported by economic, legal and ethical interests. Even though these models are essential to better understand the decision of employers and HR regarding work disability, information remains scarce regarding the concrete strategies used by these stakeholders to facilitate the return to work for employees on sick leave due to depression.Objectives the aim of this paper is to document, considering employers' and human resources' perspectives, the best strategies to put in place to facilitate the return to work of employees on sick leave due to depression.Method This study was part of a larger study carried out in Canada to assess factors influencing the return to work after a depression-related sick leave, taking into account the viewpoint of four types of stakeholders: employers/human resources, supervisors, unions and people diagnosed with depression. 219 employers (68.5%) and human resources directors (31.5%) from 82.6% organizations having more than 100 employees accepted to answer a telephone semi-structured interview. The question of interest in this study is: In your opinion, what are the best strategies to help an employee who has had a depression to return to work? Coding was influenced by empirical findings and theories related to psychosocial risk factors that the authors use in their respective disciplines as well as return to work principles/steps mentioned in the literature. The main objective was to keep all the strategies mentioned by participants, and analyzing them with major principles of return to work.Results 24 return to work strategies spread on six principles emerged: 1) Contact with the employee during his sick leave (10 strategies); 2) Evaluate and plan the return to work without precipitating it (6); 3) Training for managers and colleagues regarding mental health in the workplace (4); 4) Concertation between key return to work stakeholders (4); 5) Progressive return to work with work accommodations (4); 6) Health and work follow-up regarding the employee (6).Conclusion These six principles including 34 strategies are usually related to the timeframe process of the return to work, though they can be implemented sometimes in parallel. This possible overlap reinforces the idea to consider the return to work as sustainable in order to prevent potential relapses and improve the performance at work. Next steps will be to systematically implement these principles and strategies in organizations in order to evaluate their impact on return to work of employees on sick leave due to depression.

  10. Gender and rural-urban migration in China.

    PubMed

    Davin, D

    1996-02-01

    Many men and women in China are migrating in search of better economic opportunities. Young women who migrate to urban centers in search of opportunity may stay away from their home villages for several years. At some point, however, they are likely to return home. This article considers the effect which such circular migration is having upon gender relations in China. The author's argument is presented in sections on China's 1990 census, migration and the sexual division of labor, migration and child care, the influence of returning migrants, the influence of young female returnees, and the fertility of returnees. She speculates that the demands and expectations of young women who return to their villages after spending some time earning high wages in urban areas will be affected by urban norms. While their return may lead to initial conflict, it is likely that the women will retain greater personal autonomy from their urban experience. Their return is also likely to lead to a higher degree of material consumption in the rural areas. Present circular migration in China has the potential to return human and financial resources to the villages, thereby helping to prevent the urban-rural gap between economic, social, cultural, and educational factors from growing even wider.

  11. Maternal perspectives on the return of genetic results: context matters.

    PubMed

    Lakes, Kimberley D; Vaughan, Elaine; Lemke, Amy; Jones, Marissa; Wigal, Timothy; Baker, Dean; Swanson, James M; Burke, Wylie

    2013-01-01

    The objectives of this study were to study maternal preferences for the return of their child's genetic results and to describe the experiences, perceptions, attitudes, and values that are brought to bear when individuals from different racial and cultural backgrounds consider participating in genetic research. We recruited women with diverse sociodemographic profiles to participate in seven focus groups. Twenty-eight percent of participants self-identified as Hispanic; 49% as White, non-Hispanic; and 21% as Asian or Asian American. Focus groups were conducted in English or Spanish and were audio-recorded and transcribed verbatim. Transcripts were analyzed using qualitative thematic methods. Results indicated that preferences and decisions regarding the return of results may depend on both research and individual contextual factors. Participants understood the return of results as a complex issue, where individual and cultural differences in preferences are certain to arise. Another key finding was that participants desired an interpersonal, dynamic, flexible process that accommodated individual preferences and contextual differences for returning results. Our findings indicate a need to have well-developed systems for allowing participants to make and change over time their choices regarding the return of their child's genetic results. Copyright © 2012 Wiley Periodicals, Inc.

  12. Resources or landmarks: which factors drive homing success in Tetragonula carbonaria foraging in natural and disturbed landscapes?

    PubMed

    Leonhardt, Sara D; Kaluza, Benjamin F; Wallace, Helen; Heard, Tim A

    2016-10-01

    To date, no study has investigated how landscape structural (visual) alterations affect navigation and thus homing success in stingless bees. We addressed this question in the Australian stingless bee Tetragonula carbonaria by performing marking, release and re-capture experiments in landscapes differing in habitat homogeneity (i.e., the proportion of elongated ground features typically considered prominent visual landmarks). We investigated how landscape affected the proportion of bees and nectar foragers returning to their hives as well as the earliest time bees and foragers returned. Undisturbed landscapes with few landmarks (that are conspicuous to the human eye) and large proportions of vegetation cover (natural forests) were classified visually/structurally homogeneous, and disturbed landscapes with many landmarks and fragmented or no extensive vegetation cover (gardens and plantations) visually/structurally heterogeneous. We found that proportions of successfully returning nectar foragers and earliest times first bees and foragers returned did not differ between landscapes. However, most bees returned in the visually/structurally most (forest) and least (garden) homogeneous landscape, suggesting that they use other than elongated ground features for navigation and that return speed is primarily driven by resource availability in a landscape.

  13. Schistosoma mansoni miracidial behavior: an assay system for chemostimulation.

    PubMed

    Sponholtz, G M; Short, R B

    1975-04-01

    A new system for evaluating the responses of miracidia to chemostimulants is described. The apparatus consists of a translucent plastic block with a center well and a hole in the edge leading to the well. One end of a glass tube, covered with a dialysis membrane, was inserted into the hole. Experimental solutions to be tested were put into the tube and Schistosoma mansoni miracidial behavior was observed in the well on the other side of the permeable membrane. Miracidia were released near the membrane; those which contacted the membrane were scored as to whether they returned (contact with return) or did not return (contact without return) before leaving the field of view. Materials eliciting significantly more contact with return responses than did controls were considered to be stimulatory. In this assay system, snail (Biomphalaria glabrata) conditioned water elicited 75% contact with return as compared to 8% for well water control (P less than 0.05). Tracings from motion pictures showed swimming behavior of miracidia toward snail-conditioned water to be different from behavior toward well water controls. This system permits generation of dilution response curves for chemicals and provides generally quantitative results.

  14. Multivariate multiscale entropy of financial markets

    NASA Astrophysics Data System (ADS)

    Lu, Yunfan; Wang, Jun

    2017-11-01

    In current process of quantifying the dynamical properties of the complex phenomena in financial market system, the multivariate financial time series are widely concerned. In this work, considering the shortcomings and limitations of univariate multiscale entropy in analyzing the multivariate time series, the multivariate multiscale sample entropy (MMSE), which can evaluate the complexity in multiple data channels over different timescales, is applied to quantify the complexity of financial markets. Its effectiveness and advantages have been detected with numerical simulations with two well-known synthetic noise signals. For the first time, the complexity of four generated trivariate return series for each stock trading hour in China stock markets is quantified thanks to the interdisciplinary application of this method. We find that the complexity of trivariate return series in each hour show a significant decreasing trend with the stock trading time progressing. Further, the shuffled multivariate return series and the absolute multivariate return series are also analyzed. As another new attempt, quantifying the complexity of global stock markets (Asia, Europe and America) is carried out by analyzing the multivariate returns from them. Finally we utilize the multivariate multiscale entropy to assess the relative complexity of normalized multivariate return volatility series with different degrees.

  15. Detrended cross-correlations between returns, volatility, trading activity, and volume traded for the stock market companies

    NASA Astrophysics Data System (ADS)

    Rak, Rafał; Drożdż, Stanisław; Kwapień, Jarosław; Oświȩcimka, Paweł

    2015-11-01

    We consider a few quantities that characterize trading on a stock market in a fixed time interval: logarithmic returns, volatility, trading activity (i.e., the number of transactions), and volume traded. We search for the power-law cross-correlations among these quantities aggregated over different time units from 1 min to 10 min. Our study is based on empirical data from the American stock market consisting of tick-by-tick recordings of 31 stocks listed in Dow Jones Industrial Average during the years 2008-2011. Since all the considered quantities except the returns show strong daily patterns related to the variable trading activity in different parts of a day, which are the most evident in the autocorrelation function, we remove these patterns by detrending before we proceed further with our study. We apply the multifractal detrended cross-correlation analysis with sign preserving (MFCCA) and show that the strongest power-law cross-correlations exist between trading activity and volume traded, while the weakest ones exist (or even do not exist) between the returns and the remaining quantities. We also show that the strongest cross-correlations are carried by those parts of the signals that are characterized by large and medium variance. Our observation that the most convincing power-law cross-correlations occur between trading activity and volume traded reveals the existence of strong fractal-like coupling between these quantities.

  16. [Ten scenarios on the future of world population].

    PubMed

    Niyibizi, S

    1990-04-01

    This work presents 10 hypotheses concerning possible catastrophes that might befall the world's population in the future. The perspective is pessimistic, but in most cases the hypotheses represent possibilities only. The 1st hypothesis is that demographic imbalances resulting from the excess of births over deaths will result in a total world population too large to be sustained by the earth's finite resources. A return of the great epidemic diseases of the past or the global warming that is already threatening are 2 other possible fates, along with cooling of the atmosphere and reglaciation. Atomic, bacteriologic, and chemical warfare represents a different sort of possibility. A collision of planets or of the numerous manmade satellites now circling the earth might have disastrous consequences, as might earthquakes or floods. The end of the world is foreseen in the Bible, although details are sparse. Finally, AIDS is viewed by many as divine punishment for the perversions of the human population and by others as a viral disease capable of decimating the world's population and returning once thriving areas to an uninhabited state.

  17. Cardiovascular effects of weightlessness and ground-based simulation

    NASA Technical Reports Server (NTRS)

    Sandler, Harold

    1988-01-01

    A large number of animal and human flight and ground-based studies were conducted to uncover the cardiovascular effects of weightlessness. Findings indicate changes in cardiovascular function during simulations and with spaceflight that lead to compromised function on reambulation and/or return to earth. This altered state termed cardiovascular deconditioning is most clearly manifest when in an erect body state. Hemodynamic parameters inidicate the presence of excessive tachnycardia, hypotension (leading to presyncope in one-third of the subjects), decreased heart volume, decreased plasma and circulating blood volumes and loss of skeletal muscle mass, particularly in the lower limbs. No clinically harmful effects were observed to date, but in-depth follow-ups were limited, as was available physiologic information. Available data concerning the causes for the observed changes indicate significant roles for mechanisms involved with body fluid-volume regulation, altered cardiac function, and the neurohumoral control of the control of the peripheral circulation. Satisfactory measures are not found. Return to preflight state was variable and only slightly dependent on flight duration. Future progress awaits availability of flight durations longer than several weeks.

  18. Hepatotoxicity induced by methimazole in a previously healthy patient.

    PubMed

    Gallelli, Luca; Staltari, Orietta; Palleria, Caterina; De Sarro, Giovambattista; Ferraro, Maria

    2009-09-01

    We report a case of hepatotoxicity induced by methimazole treatment in a patient affected by hyperthyroidism. A 54-year-old man, presented to our observation for palpitations, excessive sweating, weakness, heat intolerance and weight loss. On physical examination, his blood pressure was 140/90 mmHg and heart beat was 100/min regular. He had mild tremors and left exophthalmos. Laboratory test revealed a significant increase in serum thyroid hormone levels with a decrease in thyroid stimulating hormone levels. A diagnosis of hyperthyroidism was made and he began treatment with methimazole (30 mg/day). Fourteen days later, he returned for the development of scleral icterus, followed by dark urine, and abdominal pain in the right upper quadrant. Laboratory examinations and liver biopsy performed a diagnosis of cholestatic hepatitis, secondary to methimazole usage. Methimazole was promptly withdrawn and cholestyramine, ursodeoxycholic acid, and chlorpheniramine were given. After five days, abdominal pain resolved and laboratory parameters returned to normal. Naranjo probability scale indicated a probable relationship between hepatotoxicity and methimazole therapy. In conclusion physicians should be aware the risk of hepatotoxicity related with methimazole.

  19. Funding innovation for treatment for rare diseases: adopting a cost-based yardstick approach

    PubMed Central

    2013-01-01

    Background Manufacturers justify the high prices for orphan drugs on the basis that the associated R&D costs must be spread over few patients. The proliferation of these drugs in the last three decades, combined with high prices commonly in excess of $100,000 per patient per year are placing a substantial strain on the budgets of drug plans in many countries. Do insurers spend a growing portion of their budgets on small patient populations, or leave vulnerable patients without coverage for valuable treatments? We suggest that a third option is present in the form of a cost-based regulatory mechanism. Methods This article explores the use of a cost-based price control mechanism for orphan drugs, adapted from the standard models applied in utilities regulation. Results and conclusions A rate-of-return style model, employing yardsticked cost allocations and a modified two-stage rate of return calculation could be effective in setting a new standard for orphan drugs pricing. This type of cost-based pricing would limit the costs faced by insurers while continuing to provide an efficient incentive for new drug development. PMID:24237605

  20. Continuing the Original Stanford Sleep Surgery Protocol From Upper Airway Reconstruction to Upper Airway Stimulation: Our First Successful Case.

    PubMed

    Liu, Stanley Yung; Riley, Robert Wayne

    2017-07-01

    In 1993, a surgical protocol for dynamic upper airway reconstruction in patients with obstructive sleep apnea (OSA) was published, and it became commonly known as the Stanford phase 1 and 2 sleep surgery protocol. It served as a platform on which research and clinical studies have continued to perfect the surgical care of patients with OSA. However, relapse is inevitable in a chronic condition such as OSA, and a subset of previously cured surgical patients return with complaints of excessive daytime sleepiness. This report describes a patient who was successfully treated with phase 1 and 2 operations more than a decade previously. He returned at 65 years of age with relapse of moderate OSA, and after workup with polysomnography and drug-induced sleep endoscopy, he underwent upper airway stimulation of the hypoglossal nerve that resulted in a cure of OSA. This case shows why upper airway stimulation is an appropriate option for patients with OSA relapse, after previously successful maxillomandibular advancement. Copyright © 2017. Published by Elsevier Inc.

  1. Mars rover sample return: An exobiology science scenario

    NASA Technical Reports Server (NTRS)

    Rosenthal, D. A.; Sims, M. H.; Schwartz, Deborah E.; Nedell, S. S.; Mckay, Christopher P.; Mancinelli, Rocco L.

    1988-01-01

    A mission designed to collect and return samples from Mars will provide information regarding its composition, history, and evolution. At the same time, a sample return mission generates a technical challenge. Sophisticated, semi-autonomous, robotic spacecraft systems must be developed in order to carry out complex operations at the surface of a very distant planet. An interdisciplinary effort was conducted to consider how much a Mars mission can be realistically structured to maximize the planetary science return. The focus was to concentrate on a particular set of scientific objectives (exobiology), to determine the instrumentation and analyses required to search for biological signatures, and to evaluate what analyses and decision making can be effectively performed by the rover in order to minimize the overhead of constant communication between Mars and the Earth. Investigations were also begun in the area of machine vision to determine whether layered sedimentary structures can be recognized autonomously, and preliminary results are encouraging.

  2. A Hybrid Genetic-Simulated Annealing Algorithm for the Location-Inventory-Routing Problem Considering Returns under E-Supply Chain Environment

    PubMed Central

    Guo, Hao; Fu, Jing

    2013-01-01

    Facility location, inventory control, and vehicle routes scheduling are critical and highly related problems in the design of logistics system for e-business. Meanwhile, the return ratio in Internet sales was significantly higher than in the traditional business. Many of returned merchandise have no quality defects, which can reenter sales channels just after a simple repackaging process. Focusing on the existing problem in e-commerce logistics system, we formulate a location-inventory-routing problem model with no quality defects returns. To solve this NP-hard problem, an effective hybrid genetic simulated annealing algorithm (HGSAA) is proposed. Results of numerical examples show that HGSAA outperforms GA on computing time, optimal solution, and computing stability. The proposed model is very useful to help managers make the right decisions under e-supply chain environment. PMID:24489489

  3. Protecting Biodiversity when Money Matters: Maximizing Return on Investment

    PubMed Central

    Underwood, Emma C.; Shaw, M. Rebecca; Wilson, Kerrie A.; Kareiva, Peter; Klausmeyer, Kirk R.; McBride, Marissa F.; Bode, Michael; Morrison, Scott A.; Hoekstra, Jonathan M.; Possingham, Hugh P.

    2008-01-01

    Background Conventional wisdom identifies biodiversity hotspots as priorities for conservation investment because they capture dense concentrations of species. However, density of species does not necessarily imply conservation ‘efficiency’. Here we explicitly consider conservation efficiency in terms of species protected per dollar invested. Methodology/Principal Findings We apply a dynamic return on investment approach to a global biome and compare it with three alternate priority setting approaches and a random allocation of funding. After twenty years of acquiring habitat, the return on investment approach protects between 32% and 69% more species compared to the other priority setting approaches. To correct for potential inefficiencies of protecting the same species multiple times we account for the complementarity of species, protecting up to three times more distinct vertebrate species than alternate approaches. Conclusions/Significance Incorporating costs in a return on investment framework expands priorities to include areas not traditionally highlighted as priorities based on conventional irreplaceability and vulnerability approaches. PMID:18231601

  4. Wind and wave extremes over the world oceans from very large ensembles

    NASA Astrophysics Data System (ADS)

    Breivik, Øyvind; Aarnes, Ole Johan; Abdalla, Saleh; Bidlot, Jean-Raymond; Janssen, Peter A. E. M.

    2014-07-01

    Global return values of marine wind speed and significant wave height are estimated from very large aggregates of archived ensemble forecasts at +240 h lead time. Long lead time ensures that the forecasts represent independent draws from the model climate. Compared with ERA-Interim, a reanalysis, the ensemble yields higher return estimates for both wind speed and significant wave height. Confidence intervals are much tighter due to the large size of the data set. The period (9 years) is short enough to be considered stationary even with climate change. Furthermore, the ensemble is large enough for nonparametric 100 year return estimates to be made from order statistics. These direct return estimates compare well with extreme value estimates outside areas with tropical cyclones. Like any method employing modeled fields, it is sensitive to tail biases in the numerical model, but we find that the biases are moderate outside areas with tropical cyclones.

  5. A wavelet-based evaluation of time-varying long memory of equity markets: A paradigm in crisis

    NASA Astrophysics Data System (ADS)

    Tan, Pei P.; Chin, Cheong W.; Galagedera, Don U. A.

    2014-09-01

    This study, using wavelet-based method investigates the dynamics of long memory in the returns and volatility of equity markets. In the sample of five developed and five emerging markets we find that the daily return series from January 1988 to June 2013 may be considered as a mix of weak long memory and mean-reverting processes. In the case of volatility in the returns, there is evidence of long memory, which is stronger in emerging markets than in developed markets. We find that although the long memory parameter may vary during crisis periods (1997 Asian financial crisis, 2001 US recession and 2008 subprime crisis) the direction of change may not be consistent across all equity markets. The degree of return predictability is likely to diminish during crisis periods. Robustness of the results is checked with de-trended fluctuation analysis approach.

  6. Family-friendly policies: general nurses' preferences and experiences.

    PubMed

    Robinson, Sarah; Davey, Barbara; Murrells, Trevor

    2003-01-01

    While European Union policy emphasises that one of the aims of family-friendly working arrangements is to increasing gender equality, in the UK the focus has been primarily on workforce retention. Drawing on a study of Registered General Nurses who returned to work after breaks for maternity leave, this paper considers their preferences and experiences in light of current UK family-friendly policies and the implications of the findings for increasing gender equality. Questionnaires were completed by respondents in three regional health authorities and focused on the four to eight year period after qualification. The following topics were investigated: views about length of maternity break and reasons for returning to work sooner than preferred; hours sought after a return and hours obtained; the availability of preferred patterns of work and of flexible hours; retention of grade on return; the availability and use of workplace crèches, and childcare arrangements when children were unwell.

  7. Epidemiology of Sports-Related Concussions in National Collegiate Athletic Association Athletes From 2009-2010 to 2013-2014: Symptom Prevalence, Symptom Resolution Time, and Return-to-Play Time.

    PubMed

    Wasserman, Erin B; Kerr, Zachary Y; Zuckerman, Scott L; Covassin, Tracey

    2016-01-01

    Limited data exist among collegiate student-athletes on the epidemiology of sports-related concussion (SRC) outcomes, such as symptoms, symptom resolution time, and return-to-play time. This study used the National Collegiate Athletic Association (NCAA) Injury Surveillance Program (ISP) to describe the epidemiology of SRC outcomes in 25 collegiate sports. Descriptive epidemiology study. SRC data from the NCAA ISP during the 2009-2010 to 2013-2014 academic years were analyzed regarding symptoms, time to resolution of symptoms, and time to return to play. Findings were also stratified by sex in sex-comparable sports (ie, ice hockey, soccer, basketball, lacrosse, baseball/softball) and whether SRCs were reported as recurrent. Of the 1670 concussions reported during the 2009-2010 to 2013-2014 academic years, an average (±SD) of 5.29 ± 2.94 concussion symptoms were reported, with the most common being headache (92.2%) and dizziness (68.9%). Most concussions had symptoms resolve within 1 week (60.1%); however, 6.2% had a symptom resolution time of over 4 weeks. Additionally, 8.9% of concussions required over 4 weeks before return to play. The proportion of SRCs that required at least 1 week before return to play increased from 42.7% in 2009-2010 to 70.2% in 2013-2014 (linear trend, P < .001). Within sex-comparable sports analyses, the average number of symptoms and symptom resolution time did not differ by sex. However, a larger proportion of concussions in male athletes included amnesia and disorientation; a larger proportion of concussions in female athletes included headache, excess drowsiness, and nausea/vomiting. A total of 151 SRCs (9.0%) were reported as recurrent. The average number of symptoms reported with recurrent SRCs (5.99 ± 3.43) was greater than that of nonrecurrent SRCs (5.22 ± 2.88; P = .01). A greater proportion of recurrent SRCs also resulted in a long symptom resolution time (14.6% vs 5.4%, respectively; P < .001) and long return-to-play time (21.2% vs 7.7%, respectively; P < .001) compared with nonrecurrent SRCs. Trends in return-to-play time may indicate changing concussion management practices in which team medical staff members withhold players from participation longer to ensure symptom resolution. Concussion symptoms may differ by sex and recurrence. Future research should continue to examine the trends and discrepancies in symptom resolution time and return-to-play time. © 2015 The Author(s).

  8. Excessive use of WeChat, social interaction and locus of control among college students in China

    PubMed Central

    Jiang, Yingying; Ye, Zi; Wang, Ying; Yang, Lizhuang; Li, Xiaoming; Zhang, Yongjun; Pang, Liangjun; Kong, Yan; Xu, Fei; Zhang, Xiaochu

    2017-01-01

    In China, the number of college students using mobile phone based messaging and social networking applications like WeChat is increasing rapidly. However, there has been minimal research into the addictive nature of these applications and the psychological characteristics associate with their excessive use. There is also no published scale available for assessing excessive use of WeChat and similar applications. In the current study, we collected data from 1,245 college students in China (715 females) and developed the WeChat Excessive Use Scale (WEUS). We then assessed the relationship between excessive use of WeChat and excessive use of a social networking application-Weibo, problematic use of mobile phones, external locus of control, and social interaction skills. Our 10-item scale featured three factors, namely- “mood modification,” “salience” and ‘‘conflict”- critical factors in assessing different forms of addiction. The WEUS was found to be a reliable instrument in assessing excessive use of WeChat as it showed good internal consistency and correlated with other measures of problematic use social networking and mobile phone addiction. Our results showed that excessive users of WeChat are more likely to excessively use Weibo than they are to problematically use mobile phones. Our study also showed that greater excessive use of WeChat is associated with higher external locus of control and greater online social interaction skills. These results reveal that WeChat has unique and strong appeal among college students in China. Further, practitioners should consider dealing with malleable factors like locus of control and real life social skills in treating people with problematic messaging and social networking. PMID:28817710

  9. Excessive use of WeChat, social interaction and locus of control among college students in China.

    PubMed

    Hou, Juan; Ndasauka, Yamikani; Jiang, Yingying; Ye, Zi; Wang, Ying; Yang, Lizhuang; Li, Xiaoming; Zhang, Yongjun; Pang, Liangjun; Kong, Yan; Xu, Fei; Zhang, Xiaochu

    2017-01-01

    In China, the number of college students using mobile phone based messaging and social networking applications like WeChat is increasing rapidly. However, there has been minimal research into the addictive nature of these applications and the psychological characteristics associate with their excessive use. There is also no published scale available for assessing excessive use of WeChat and similar applications. In the current study, we collected data from 1,245 college students in China (715 females) and developed the WeChat Excessive Use Scale (WEUS). We then assessed the relationship between excessive use of WeChat and excessive use of a social networking application-Weibo, problematic use of mobile phones, external locus of control, and social interaction skills. Our 10-item scale featured three factors, namely- "mood modification," "salience" and ''conflict"- critical factors in assessing different forms of addiction. The WEUS was found to be a reliable instrument in assessing excessive use of WeChat as it showed good internal consistency and correlated with other measures of problematic use social networking and mobile phone addiction. Our results showed that excessive users of WeChat are more likely to excessively use Weibo than they are to problematically use mobile phones. Our study also showed that greater excessive use of WeChat is associated with higher external locus of control and greater online social interaction skills. These results reveal that WeChat has unique and strong appeal among college students in China. Further, practitioners should consider dealing with malleable factors like locus of control and real life social skills in treating people with problematic messaging and social networking.

  10. Causes, Patterns, and Severity of Androgen Excess in 1205 Consecutively Recruited Women.

    PubMed

    Elhassan, Yasir S; Idkowiak, Jan; Smith, Karen; Asia, Miriam; Gleeson, Helena; Webster, Rachel; Arlt, Wiebke; O'Reilly, Michael W

    2018-03-01

    Androgen excess in women is predominantly due to underlying polycystic ovary syndrome (PCOS). However, there is a lack of clarity regarding patterns and severity of androgen excess that should be considered predictive of non-PCOS pathology. We examined the diagnostic utility of simultaneous measurement of serum dehydroepiandrosterone sulfate (DHEAS), androstenedione (A4), and testosterone (T) to delineate biochemical signatures and cutoffs predictive of non-PCOS disorders in women with androgen excess. Retrospective review of all women undergoing serum androgen measurement at a large tertiary referral center between 2012 and 2016. Serum A4 and T were measured by tandem mass spectrometry and DHEAS by immunoassay. Patients with at least one increased serum androgen underwent phenotyping by clinical notes review. In 1205 women, DHEAS, A4, and T were measured simultaneously. PCOS was the most common diagnosis in premenopausal (89%) and postmenopausal women (29%). A4 was increased in all adrenocortical carcinoma (ACC) cases (n = 15) and T in all ovarian hyperthecosis (OHT) cases (n = 7); all but one case of congenital adrenal hyperplasia (CAH; n = 18) were identified by increased levels of A4 and/or T. In premenopausal women, CAH was a prevalent cause of severe A4 (59%) and T (43%) excess; severe DHEAS excess was predominantly due to PCOS (80%). In postmenopausal women, all cases of severe DHEAS and A4 excess were caused by ACC and severe T excess equally by ACC and OHT. Pattern and severity of androgen excess are important predictors of non-PCOS pathology and may be used to guide further investigations as appropriate.

  11. Excessive consumption of dietary supplements among professionals working in gyms in Pelotas, Rio Grande do Sul State, Brazil, 2012.

    PubMed

    Cava, Tatiane Araujo; Madruga, Samanta Winck; Teixeira, Gesiane Dias Trindade; Reichert, Felipe Fossati; Silva, Marcelo Cozzensa da; Rombaldi, Airton José

    2017-01-01

    to investigate the prevalence and factors associated with excessive consumption of dietary supplements among professionals working at gyms in Pelotas, Rio Grande do Sul State, Brazil. this is a cross-sectional study with all local fitness professionals identified in 2012; excessive consumption of dietary supplements was defined as the use of three or more types of supplements simultaneously; multivariate analysis was carried out using Poisson regression with robust variance. 497 professionals were interviewed; the prevalence of excessive consumption of dietary supplements was 10.5% (95%CI 7.9;13.5); there was association with the male sex (PR=3.2; 95%CI 1.6;6.7) and with length of time of dietary supplement consumption ≥4 years when compared to <1 year (PR=2.8; 95%CI 1.7;4.7); lower consumption was found among professionals with higher levels of education, regardless of whether they had a degree in physical education or not (p=0,007). prevalence of excessive consumption of dietary supplements can be considered high and was associated with sociodemographic variables.

  12. Effects of personality on overtime work: a cross-sectional pilot study among Japanese white-collar workers.

    PubMed

    Uchida, Mitsuo; Kaneko, Minoru; Kawa, Shigeyuki

    2014-03-27

    As detailed associations between personality and long work hours are unclear, we assessed associations between personality dimensions and overtime work among Japanese white-collar workers. From records of hours worked over 12 months by 267 office workers in an organization within the service industry, average overtime work hours per month and occurrence of excessive overtime was determined for each worker. Excessive overtime was defined as >  45 overtime work hours per month for at least one month. Responses to a questionnaire assessing socio-demographic and workplace-related factors and the Big Five personality test were analyzed. Associations between personality factors and overtime work were assessed by multivariate logistic regression analysis. Low Extraversion was associated with excessive overtime work (OR 2.02, 95%CI 1.02 - 4.02, P =  0.04). It is suggested that workers with low Extraversion can't share work when busy to avoid excessive overtime. Personality factors should be considered in studies evaluating work time. Moreover, strengthening communication among workers with low Extraversion may reduce excessive overtime work and associated health problems.

  13. Depression, materialism, and excessive Internet use in relation to compulsive buying.

    PubMed

    Mueller, Astrid; Mitchell, James E; Peterson, Lisa A; Faber, Ronald J; Steffen, Kristine J; Crosby, Ross D; Claes, Laurence

    2011-01-01

    The objective of the study was to examine the relationship between compulsive buying (CB), depression, materialism, and excessive Internet use. An online survey of 387 consumers was conducted including questions about demographics and shopping venues, the Compulsive Buying Scale, the Patient Health Questionnaire Depression Scale, the Materialistic Values Scale, and questions concerning excessive Internet use. Seventeen percent of the participants reported Compulsive Buying Scale scores less than -1.34 and were considered to be having CB. Participants with CB did not significantly differ from those without CB regarding age, sex, marital status, annual household income, and shopping preferences. Individuals with CB reported more depressive symptoms, higher materialistic values endorsement, and more severe excessive Internet use compared with those without CB. Results of a stepwise logistic regression analysis with CB as the dependent variable showed that materialism and depression were associated with CB, whereas excessive Internet use was not. Materialism and depression jointly influence CB. Further research is needed to examine the influence of materialism on CB in a clinical sample consisting of patients with diagnosed CB. Copyright © 2011 Elsevier Inc. All rights reserved.

  14. Is the Epworth Sleepiness Scale a useful tool for screening excessive daytime sleepiness in commercial drivers?

    PubMed

    Baiardi, Simone; La Morgia, Chiara; Sciamanna, Lucia; Gerosa, Alberto; Cirignotta, Fabio; Mondini, Susanna

    2018-01-01

    The significant social and economic impact of excessive daytime sleepiness makes sleep evaluation a primary medical need in commercial drivers. However, the best screening tool is still matter of debate. In our cohort of 221 commercial drivers, only ten (4.5%) had Epworth Sleepiness Scale scores indicative of excessive daytime sleepiness. These findings and the lack of concordance in estimating excessive daytime sleepiness among commercial drivers in previous studies using the same psychometric measure indicate that the Epworth Sleepiness Scale is not a reliable tool. This may be due to the low internal consistency of the scale in non-clinical samples and the possible intentional underscoring of sleepiness due to a perceived threat of driver's license suspension. Moreover, the reliability of the Epworth Sleepiness Scale results may be strongly influenced by the administration setting. The clinical application of inexpensive less time-consuming new tools like performance tests should be considered for the objective evaluation of excessive daytime sleepiness in commercial drivers. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Potential impacts of radon, terrestrial gamma and cosmic rays on childhood leukemia in France: a quantitative risk assessment.

    PubMed

    Laurent, Olivier; Ancelet, Sophie; Richardson, David B; Hémon, Denis; Ielsch, Géraldine; Demoury, Claire; Clavel, Jacqueline; Laurier, Dominique

    2013-05-01

    Previous epidemiological studies and quantitative risk assessments (QRA) have suggested that natural background radiation may be a cause of childhood leukemia. The present work uses a QRA approach to predict the excess risk of childhood leukemia in France related to three components of natural radiation: radon, cosmic rays and terrestrial gamma rays, using excess relative and absolute risk models proposed by the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). Both models were developed from the Life Span Study (LSS) of Japanese A-bomb survivors. Previous risk assessments were extended by considering uncertainties in radiation-related leukemia risk model parameters as part of this process, within a Bayesian framework. Estimated red bone marrow doses cumulated during childhood by the average French child due to radon, terrestrial gamma and cosmic rays are 4.4, 7.5 and 4.3 mSv, respectively. The excess fractions of cases (expressed as percentages) associated with these sources of natural radiation are 20 % [95 % credible interval (CI) 0-68 %] and 4 % (95 % CI 0-11 %) under the excess relative and excess absolute risk models, respectively. The large CIs, as well as the different point estimates obtained under these two models, highlight the uncertainties in predictions of radiation-related childhood leukemia risks. These results are only valid provided that models developed from the LSS can be transferred to the population of French children and to chronic natural radiation exposures, and must be considered in view of the currently limited knowledge concerning other potential risk factors for childhood leukemia. Last, they emphasize the need for further epidemiological investigations of the effects of natural radiation on childhood leukemia to reduce uncertainties and help refine radiation protection standards.

  16. Initial Sample Analyses inside a Capsule: A Strategy of Life Detection and Planetary Protection for Ocean World Sample Return Missions

    NASA Astrophysics Data System (ADS)

    Yano, Hajime; Takano, Yoshinori; Sekine, Yasuhito; Takai, Ken; Funase, Ryu; Fujishima, Kosuke; Shibuya, Takazo

    2016-07-01

    Planetary protection is considered to be one of the most crucial challenges to enable sample return missions from "Ocean Worlds", internal oceans of icy satellites as potential deep habitat such as Enceladus and Europa, due to the risk of backward contamination of bringing back potential biology-related matters or at most, possible extraterrestrial living signatures to the Earth. Here we propose an innovative technological solution for both life detection and planetary protection of such returned samples, namely by conducting all major life signature searches, which are also a critical path of quarantine processes of planetary protection, inside the Earth return capsule, prior to open the canister and expose to the terrestrial environment. We plan to test the latest sample capture and recovery methods of preparing multiple aliquot chambers in the sample return capsule. Each aliquot chamber will trap, for instance, plume particles and ambient volatiles during the spacecraft flying through Enceladus plumes so that respective analyses can be performed focusing on volatiles and minerals (i.e., habitability for life), organics (i.e., ingredients for life), biosignatures (i.e., activity of life) and for archiving the samples for future investigations at the same time. In-situ analysis will be conducted under complete containment through an optical interface port that allows pre-installed fiber optic cables to perform non-contact measurements and capillary tubing for extraction/injection of gas and liquids through metal barriers to be punctuated inside a controlled environment. Once primary investigations are completed, the interior of the capsule will be sterilized by gamma rays and UV irradiation. Post-sterilized aliquot chambers will be further analyzed under enclosed and ultraclean environment at BAL 2-3 facilities, rather than BSL4. We consider that this is an unique solution that can cope with severe requirements set for the Category-V sample returns for astrobiology-driven missions.

  17. The foreign exchange market: return distributions, multifractality, anomalous multifractality and the Epps effect

    NASA Astrophysics Data System (ADS)

    Drożdż, Stanisław; Kwapień, Jarosław; Oświȩcimka, Paweł; Rak, Rafał

    2010-10-01

    We present a systematic study of various statistical characteristics of high-frequency returns from the foreign exchange market. This study is based on six exchange rates forming two triangles: EUR-GBP-USD and GBP-CHF-JPY. It is shown that the exchange rate return fluctuations for all of the pairs considered are well described by the non-extensive statistics in terms of q-Gaussians. There exist some small quantitative variations in the non-extensivity q-parameter values for different exchange rates (which depend also on the time scales studied), and this can be related to the importance of a given exchange rate in the world's currency trade. Temporal correlations organize the series of returns such that they develop the multifractal characteristics for all of the exchange rates, with a varying degree of symmetry of the singularity spectrum f(α), however. The most symmetric spectrum is identified for the GBP/USD. We also form time series of triangular residual returns and find that the distributions of their fluctuations develop disproportionately heavier tails as compared to small fluctuations, which excludes description in terms of q-Gaussians. The multifractal characteristics of these residual returns reveal such anomalous properties as negative singularity exponents and even negative singularity spectra. Such anomalous multifractal measures have so far been considered in the literature in connection with diffusion-limited aggregation and with turbulence. Studying the cross-correlations among different exchange rates, we found that market inefficiency on short time scales leads to the occurrence of the Epps effect on much longer time scales, but comparable to the ones for the stock market. Although the currency market is much more liquid than the stock markets and has a much greater transaction frequency, the building up of correlations takes up to several hours—a duration that does not differ much from what is observed in the stock markets. This may suggest that non-synchronicity of transactions is not the unique source of the observed effect.

  18. Implications of the Naturalistic Decision Making Framework for Information Dominance.

    DTIC Science & Technology

    1997-07-01

    Information Dominance , defined as an operational advantage obtained through superior effectiveness of informational activity. NDM is the study of how people use their experience to make decisions in field settings. Expertise was considered at both the individual and the team level of decision making. The report defines the components of expertise and identifies obstacles to the acquisition of Information Dominance . These obstacles include: (1) excessive data, (2) pre-processed data, (3) excessive procedures, (4) performing formal analyses, (5) passive

  19. Retraining Attentional Bias to Unhealthy Food Cues

    DTIC Science & Technology

    2013-06-26

    Obesity ’Overweight’ and ’Obese’ describe levels of body fat (i.e., adiposity) that exceed ranges of weight that are considered healthy for a given...to an accumulation of excess body fat . Obesity is further divided into Class I (30.0 - 34.9 kg/m2) and Class II obesity (35.0 - 39.9 kg/m2) and Class...weight gain through excessive consumption of palatable foods that contain large amounts of fat and sugar. Processed foods such as those from fast food

  20. Effect of External Economic-Field Cycle and Market Temperature on Stock-Price Hysteresis: Monte Carlo Simulation on the Ising Spin Model

    NASA Astrophysics Data System (ADS)

    Punya Jaroenjittichai, Atchara; Laosiritaworn, Yongyut

    2017-09-01

    In this work, the stock-price versus economic-field hysteresis was investigated. The Ising spin Hamiltonian was utilized as the level of ‘disagreement’ in describing investors’ behaviour. The Ising spin directions were referred to an investor’s intention to perform his action on trading his stock. The periodic economic variation was also considered via the external economic-field in the Ising model. The stochastic Monte Carlo simulation was performed on Ising spins, where the steady-state excess demand and supply as well as the stock-price were extracted via the magnetization. From the results, the economic-field parameters and market temperature were found to have significant effect on the dynamic magnetization and stock-price behaviour. Specifically, the hysteresis changes from asymmetric to symmetric loops with increasing market temperature and economic-field strength. However, the hysteresis changes from symmetric to asymmetric loops with increasing the economic-field frequency, when either temperature or economic-field strength is large enough, and returns to symmetric shape at very high frequencies. This suggests competitive effects among field and temperature factors on the hysteresis characteristic, implying multi-dimensional complicated non-trivial relationship among inputs-outputs. As is seen, the results reported (over extensive range) can be used as basis/guideline for further analysis/quantifying how economic-field and market-temperature affect the stock-price distribution on the course of economic cycle.

  1. Ensuring Success of Adaptive Control Research Through Project Lifecycle Risk Mitigation

    NASA Technical Reports Server (NTRS)

    Pavlock, Kate M.

    2011-01-01

    Lessons Learne: 1. Design-out unnecessary risk to prevent excessive mitigation management during flight. 2. Consider iterative checkouts to confirm or improve human factor characteristics. 3. Consider the total flight test profile to uncover unanticipated human-algorithm interactions. 4. Consider test card cadence as a metric to assess test readiness. 5. Full-scale flight test is critical to development, maturation, and acceptance of adaptive control laws for operational use.

  2. Principles of light energy management

    NASA Astrophysics Data System (ADS)

    Davis, N.

    1994-03-01

    Six methods used to minimize excess energy effects associated with lighting systems for plant growth chambers are reviewed in this report. The energy associated with wall transmission and chamber operating equipment and the experimental requirements, such as fresh air and internal equipment, are not considered here. Only the energy associated with providing and removing the energy for lighting is considered.

  3. Principles of light energy management

    NASA Technical Reports Server (NTRS)

    Davis, N.

    1994-01-01

    Six methods used to minimize excess energy effects associated with lighting systems for plant growth chambers are reviewed in this report. The energy associated with wall transmission and chamber operating equipment and the experimental requirements, such as fresh air and internal equipment, are not considered here. Only the energy associated with providing and removing the energy for lighting is considered.

  4. 38 CFR 4.24 - Correspondence.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... adequate picture of the claimant's condition. Claims in regard to which the schedule evaluations are considered inadequate or excessive, and errors in the schedule will be similarly brought to attention. [41 FR...

  5. Estimates of thermochemical relaxation lengths behind normal shock waves relevant to manned lunar and Mars return missions, the aeroassist flight experiment, and Mars entry

    NASA Technical Reports Server (NTRS)

    Howe, John T.

    1991-01-01

    Thermochemical relaxation distances behind the strong normal shock waves associated with vehicles that enter the Earth atmosphere upon returning from a manned lunar or Mars mission are estimated. The relaxation distances for a Mars entry are estimated as well, in order to highlight the extent of the relaxation phenomena early in currently envisioned space exploration studies. The thermochemical relaxation length for the Aeroassist Flight Experiment is also considered. These estimates provide an indication as to whether finite relaxation needs to be considered in subsequent detailed analyses. For the Mars entry, relaxation phenomena that are fully coupled to the flow field equations are used. The relaxation-distance estimates can be scaled to flight conditions other than those discussed.

  6. Optimal timing in biological processes

    USGS Publications Warehouse

    Williams, B.K.; Nichols, J.D.

    1984-01-01

    A general approach for obtaining solutions to a class of biological optimization problems is provided. The general problem is one of determining the appropriate time to take some action, when the action can be taken only once during some finite time frame. The approach can also be extended to cover a number of other problems involving animal choice (e.g., mate selection, habitat selection). Returns (assumed to index fitness) are treated as random variables with time-specific distributions, and can be either observable or unobservable at the time action is taken. In the case of unobservable returns, the organism is assumed to base decisions on some ancillary variable that is associated with returns. Optimal policies are derived for both situations and their properties are discussed. Various extensions are also considered, including objective functions based on functions of returns other than the mean, nonmonotonic relationships between the observable variable and returns; possible death of the organism before action is taken; and discounting of future returns. A general feature of the optimal solutions for many of these problems is that an organism should be very selective (i.e., should act only when returns or expected returns are relatively high) at the beginning of the time frame and should become less and less selective as time progresses. An example of the application of optimal timing to a problem involving the timing of bird migration is discussed, and a number of other examples for which the approach is applicable are described.

  7. Theoretical study of the composition pulling effect in InGaN metalorganic vapor-phase epitaxy growth

    NASA Astrophysics Data System (ADS)

    Inatomi, Yuya; Kangawa, Yoshihiro; Ito, Tomonori; Suski, Tadeusz; Kumagai, Yoshinao; Kakimoto, Koichi; Koukitu, Akinori

    2017-07-01

    The composition pulling effect in metalorganic vapor-phase InGaN epitaxy was theoretically investigated by thermodynamic analysis. The excess energies of biaxial-strained In x Ga1- x N were numerically calculated using empirical interatomic potentials considering different situations: (i) coherent growth on GaN(0001), (ii) coherent growth on In0.2Ga0.8N(0001), and (iii) bulk growth. Using the excess energies, the excess chemical potentials of InN and GaN alloys were computed. Our results show that compressive strain suppresses In incorporation, whereas tensile strain promotes it. Moreover, assuming chemical equilibrium, the relationship between the solid composition and the growth conditions was predicted. The results successfully reproduced the typical composition pulling effect.

  8. Narcolepsy in children: a diagnostic and management approach.

    PubMed

    Babiker, Mohamed O E; Prasad, Manish

    2015-06-01

    To provide a diagnostic and management approach for narcolepsy in children. Narcolepsy is a chronic disabling disorder characterized by excessive daytime sleepiness, cataplexy, hypnogogic and/or hypnopompic hallucinations, and sleep paralysis. All four features are present in only half of the cases. Excessive daytime sleepiness is the essential feature of narcolepsy at any age and is usually the first symptom to manifest. A combination of excessive daytime sleepiness and definite cataplexy is considered pathognomonic of narcolepsy syndrome. New treatment options have become available over the past few years. Early diagnosis and management can significantly improve the quality of life of patients with narcolepsy with cataplexy. This review summarizes the pathophysiology, clinical features, and management options for children with narcolepsy. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. A Gearless Safe and Arming Device for Artillery Firing (Program Summary and Mathematical Analysis)

    DTIC Science & Technology

    1975-09-01

    not return it to the originator. The findings in this report are not to be constued as an official De - partment of the Army position unless so...MECHANICS OF THE GEARLESS S&A MECHANISM 72 Friction Not Considered 17 Friction Considerations 7 3 Mesh Friction 73 Bearing Friction Other System ...Size) 18 5 DVA Gearless Booster (M572E2 Size) 20 6 Gearless S&A: Design 2; Configuration 3 29 7 Returnable Setback System 31 8 Lower Lever

  10. Optimization of Return Trajectories for Orbital Transfer Vehicle between Earth and Moon

    NASA Technical Reports Server (NTRS)

    Funase, Ryu; Tsuda, Yuichi; Kawaguchi, Jun'ichiro

    2007-01-01

    In this paper, optimum trajectories in Earth Transfer Orbit (ETO) for a lunar transportation system are proposed. This paper aims at improving the payload ratio of the reusable orbital transfer vehicle (OTV), which transports the payload from Low Earth Orbit (LEO) to Lunar Low Orbit (LLO) and returns to LEO. In ETO, we discuss ballistic flight using chemical propulsion, multi-impulse flight using electrical propulsion, and aero-assisted flight using aero-brake. The feasibility of the OTV is considered.

  11. Satellite services system analysis study. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Service requirements are considered. Topics include development of on-orbit operations scenarios, service equipment summary, crew interaction, and satellite features facilitating servicing. Service equipment concepts are considered. Topics include payload deployment, close proximity retrieval, on-orbit servicing, backup/contingency, delivery/retrieval of high energy payloads, Earth return, optional service, and advanced capabilities. Program requirements are assessed.

  12. 7 CFR 1410.12 - Emergency Forestry Program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., may be considered for priority purposes. These include but are not limited to soil erosion prevention, water quality improvement, wildlife habitat restoration, and mitigation of economic loss. (h) In return...

  13. 7 CFR 1410.12 - Emergency Forestry Program.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., may be considered for priority purposes. These include but are not limited to soil erosion prevention, water quality improvement, wildlife habitat restoration, and mitigation of economic loss. (h) In return...

  14. Progression of mechanical properties during on-field sprint running after returning to sports from a hamstring muscle injury in soccer players.

    PubMed

    Mendiguchia, J; Samozino, P; Martinez-Ruiz, E; Brughelli, M; Schmikli, S; Morin, J-B; Mendez-Villanueva, A

    2014-07-01

    The objectives of this study were to examine the consequences of an acute hamstring injury on performance and mechanical properties of sprint-running at the time of returning to sports and after the subsequent ~2 months of regular soccer training after return. 28 semi-professional male soccer players, 14 with a recent history of unilateral hamstring injury and 14 without prior injury, participated in the study. All players performed two 50-m maximal sprints when cleared to return to play (Test 1), and 11 injured players performed the same sprint test about 2 months after returning to play (Test 2). Sprint performance (i. e., speed) was measured via a radar gun and used to derive linear horizontal force-velocity relationships from which the following variables obtained: theoretical maximal velocity (V(0)), horizontal force (F(H0)) and horizontal power (Pmax). Upon returning to sports the injured players were moderately slower compared to the uninjured players. F H0 and Pmax were also substantially lower in the injured players. At Test 2, the injured players showed a very likely increase in F(H0) and Pmax concomitant with improvements in early acceleration performance. Practitioners should consider assessing and training horizontal force production during sprint running after acute hamstring injuries in soccer players before they return to sports. © Georg Thieme Verlag KG Stuttgart · New York.

  15. Diminishing returns and Malthus's first essay on population: theory and application.

    PubMed

    Hollander, S

    1989-06-01

    "This paper argues that Malthus's famous geometrical and arithmetical ratios do not necessarily imply diminishing returns. That average product would not necessarily fall with increased population density is immaterial to the polemical purpose of the Essay on Population which is satisfied by demonstrating the necessity for a reduction of the population growth below its maximum potential. But I do not deny the presence of the diminishing returns principle in the first Essay. Indeed, here is found the origin of Malthus's later land-scarcity based growth model involving a declining path of real wages in consequence of a decelerating rate of growth of labour demand." The author also considers Malthus's analysis of the situation in Britain in 1798. (SUMMARY IN FRE) excerpt

  16. Early UV emission from disc-originated matter (DOM) in Type Ia supernovae in the double-degenerate scenario

    NASA Astrophysics Data System (ADS)

    Levanon, Naveh; Soker, Noam

    2017-09-01

    We show that the blue and UV excess emission in the first few days of some Type Ia supernovae (SNe Ia) can be accounted in the double-degenerate (DD) scenario by the collision of the SN ejecta with circumstellar matter that was blown by the accretion disc formed during the merger process of the two white dwarfs (WDs). We assume that in cases of excess early light, the disc blows the circumstellar matter, that we term disc-originated matter (DOM), hours to days before explosion. To perform our analysis, we first provide a model-based definition for early excess light, replacing the definition of excess light relative to a power-law fit to the rising luminosity. We then examine the light curves of the SNe Ia iPTF14atg and SN 2012cg, and find that the collision of the ejecta with a DOM in the frame of the DD scenario can account for their early excess emission. Thus, early excess light does not necessarily imply the presence of a stellar companion in the frame of the single-degenerate scenario. Our findings further increase the variety of phenomena that the DD scenario can account for, and emphasize the need to consider all different SN Ia scenarios when interpreting observations.

  17. Injury severity at presentation is not associated with long-term vocational outcome in British Military brain injury.

    PubMed

    Bahadur, Sardar; McGilloway, E; Etherington, J

    2016-04-01

    Injury Severity Score (ISS) and GCS can be retrospective markers of injury severity, but if used by clinicians to decide on the treatment of acutely brain-injured casualties at the point of injury may potentially limit interventions on people who may ultimately survive with good functional outcomes. ISS/GCS and long-term outcomes were reviewed by assessing all UK military neurorehabilitation patients with an operational/combat brain injury treated over 4 years (February 2008-July 2012) at Defence Medical Rehabilitation Centre (Headley Court). 34 participants from 9 operational tours of Iraq and Afghanistan were analysed. Overall, 44% of injuries were due to improvised explosive devices (IEDs) and 41% from gunshot wounds; 70.9% of injuries were penetrating wounds with the remainder due to blast/blunt trauma or combined injury. The primary injury was head/neck in 76.5%, although eight patients (23.4%) requiring neurorehabilitation were initially 'non-head injury'. Eight patients (26.5%) sustained more than 10 injuries, and 18 had between three and nine injuries. Eleven patients (32%) had an initial GCS of 3, and 16 (47%) had ISS of 75 (deemed 'unsurvivable'). All patients with ISS of 75 were long-term survivors. At 4 months after discharge, 47% (16) were fully independent, and a further 41% (14) were independent in own homes, but needed assistance with some activities, such as paying bills. Over three-quarters (27 patients, 79%) returned to full/part-time work, 11 of whom returned to military duties; 93% of 'unsurvivable' ISS, and 91% of patients with GCS of 3 were capable of returning/returned to work. In total, 7/11 casualties returning to military duties had major trauma ISS, and two were 'unsurvivable'. All seven casualties with both GCS 3 and ISS 75 survived and returned to independence (help with some activities). ISS/GCS at the point of injury does not reflect eventual outcome. IEDs/gunshots cause the greatest number of injuries and the highest incidence of brain injury. Brain injury should be considered in every battlefield casualty, irrespective of whether the head/neck/spinal cord was avoided. ISS should not be considered indicative or predictive of long-term prognosis/quality of life/employability as brain injury in this small cohort is both survivable and recoverable. It should not be used as a retrospective guide to alter treatment pathways, as there is poor correlation with long-term outcome. Subsequent neurorehabilitation should always be considered because survival, return to independence and full employment are very likely. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  18. How gravitational lensing helps γ-ray photons avoid γ – γ absorption

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barnacka, Anna; Böttcher, Markus; Sushch, Iurii, E-mail: abarnacka@cfa.harvard.edu, E-mail: Markus.Bottcher@nwu.ac.za

    2014-08-01

    We investigate potential γ – γ absorption of γ-ray emission from blazars arising from inhomogeneities along the line of sight, beyond the diffuse Extragalactic Background Light (EBL). As plausible sources of excess γ – γ opacity, we consider (1) foreground galaxies, including cases in which this configuration leads to strong gravitational lensing, (2) individual stars within these foreground galaxies, and (3) individual stars within our own galaxy, which may act as lenses for microlensing events. We found that intervening galaxies close to the line of sight are unlikely to lead to significant excess γ – γ absorption. This opens upmore » the prospect of detecting lensed gamma-ray blazars at energies above 10 GeV with their gamma-ray spectra effectively only affected by the EBL. The most luminous stars located either in intervening galaxies or in our galaxy provide an environment in which these gamma-rays could, in principle, be significantly absorbed. However, despite a large microlensing probability due to stars located in intervening galaxies, γ-rays avoid absorption by being deflected by the gravitational potentials of such intervening stars to projected distances ({sup i}mpact parameters{sup )} where the resulting γ – γ opacities are negligible. Thus, neither of the intervening excess photon fields considered here, provide a substantial source of excess γ – γ opacity beyond the EBL, even in the case of very close alignments between the background blazar and a foreground star or galaxy.« less

  19. Excess costs of social anxiety disorder in Germany.

    PubMed

    Dams, Judith; König, Hans-Helmut; Bleibler, Florian; Hoyer, Jürgen; Wiltink, Jörg; Beutel, Manfred E; Salzer, Simone; Herpertz, Stephan; Willutzki, Ulrike; Strauß, Bernhard; Leibing, Eric; Leichsenring, Falk; Konnopka, Alexander

    2017-04-15

    Social anxiety disorder is one of the most frequent mental disorders. It is often associated with mental comorbidities and causes a high economic burden. The aim of our analysis was to estimate the excess costs of patients with social anxiety disorder compared to persons without anxiety disorder in Germany. Excess costs of social anxiety disorder were determined by comparing two data sets. Patient data came from the SOPHO-NET study A1 (n=495), whereas data of persons without anxiety disorder originated from a representative phone survey (n=3213) of the general German population. Missing data were handled by "Multiple Imputation by Chained Equations". Both data sets were matched using "Entropy Balancing". Excess costs were calculated from a societal perspective for the year 2014 using general linear regression with a gamma distribution and log-link function. Analyses considered direct costs (in- and outpatient treatment, rehabilitation, and professional and informal care) and indirect costs due to absenteeism from work. Total six-month excess costs amounted to 451€ (95% CI: 199€-703€). Excess costs were mainly caused by indirect excess costs due to absenteeism from work of 317€ (95% CI: 172€-461€), whereas direct excess costs amounted to 134€ (95% CI: 110€-159€). Costs for medication, unemployment and disability pension was not evaluated. Social anxiety disorder was associated with statistically significant excess costs, in particular due to indirect costs. As patients in general are often unaware of their disorder or its severity, awareness should be strengthened. Prevention and early treatment might reduce long-term indirect costs. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Distributed watershed modeling of design storms to identify nonpoint source loading areas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Endreny, T.A.; Wood, E.F.

    1999-03-01

    Watershed areas that generate nonpoint source (NPS) polluted runoff need to be identified prior to the design of basin-wide water quality projects. Current watershed-scale NPS models lack a variable source area (VSA) hydrology routine, and are therefore unable to identify spatially dynamic runoff zones. The TOPLATS model used a watertable-driven VSA hydrology routine to identify runoff zones in a 17.5 km{sup 2} agricultural watershed in central Oklahoma. Runoff areas were identified in a static modeling framework as a function of prestorm watertable depth and also in a dynamic modeling framework by simulating basin response to 2, 10, and 25 yrmore » return period 6 h design storms. Variable source area expansion occurred throughout the duration of each 6 h storm and total runoff area increased with design storm intensity. Basin-average runoff rates of 1 mm h{sup {minus}1} provided little insight into runoff extremes while the spatially distributed analysis identified saturation excess zones with runoff rates equaling effective precipitation. The intersection of agricultural landcover areas with these saturation excess runoff zones targeted the priority potential NPS runoff zones that should be validated with field visits. These intersected areas, labeled as potential NPS runoff zones, were mapped within the watershed to demonstrate spatial analysis options available in TOPLATS for managing complex distributions of watershed runoff. TOPLATS concepts in spatial saturation excess runoff modelling should be incorporated into NPS management models.« less

  1. Influence of footwear designed to boost energy return on running economy in comparison to a conventional running shoe.

    PubMed

    Sinclair, J; Mcgrath, R; Brook, O; Taylor, P J; Dillon, S

    2016-01-01

    Running economy is a reflection of the amount of inspired oxygen required to maintain a given velocity and is considered a determining factor for running performance. Athletic footwear has been advocated as a mechanism by which running economy can be enhanced. New commercially available footwear has been developed in order to increase energy return, although their efficacy has not been investigated. This study aimed to examine the effects of energy return footwear on running economy in relation to conventional running shoes. Twelve male runners completed 6-min steady-state runs in conventional and energy return footwear. Overall, oxygen consumption (VO2), heart rate, respiratory exchange ratio, shoe comfort and rating of perceived exertion were assessed. Moreover, participants subjectively indicated which shoe condition they preferred for running. Differences in shoe comfort and physiological parameters were examined using Wilcoxon signed-rank tests, whilst shoe preferences were tested using a chi-square analysis. The results showed that VO2 and respiratory exchange ratio were significantly lower, and shoe comfort was significantly greater, in the energy return footwear. Given the relationship between running economy and running performance, these observations indicate that the energy return footwear may be associated with enhanced running performance in comparison to conventional shoes.

  2. Return Migrants' Experience of Access to Care in Corrupt Healthcare Systems: The Bosnian Example.

    PubMed

    Neerup Handlos, Line; Fog Olwig, Karen; Bygbjerg, Ib Christian; Norredam, Marie

    2016-09-19

    Equal and universal access to healthcare services is a core priority for a just health system. A key societal determinant seen to create inequality in access to healthcare is corruption in the healthcare system. How return migrants' access to healthcare is affected by corruption is largely unstudied, even though return migrants may be particularly vulnerable to problems related to corruption due to their period of absence from their country of origin. This article investigates how corruption in the healthcare sector affects access to healthcare for refugees who repatriated to Bosnia, a country with a high level of corruption, from Denmark, a country with a low level of corruption. The study is based on 18 semi-structured interviews with 33 refugees who returned after long-term residence in Denmark. We found that the returned refugees faced greater problems with corruption than was the case for those who had not left the country, as doctors considered them to be better endowed financially and therefore demanded larger bribes from them than they did from those who had remained in Bosnia. Moreover, during their stay abroad the returnees had lost the connections that could have helped them sidestep the corruption. Returned refugees are thus particularly vulnerable to the effects of corruption.

  3. Return Migrants’ Experience of Access to Care in Corrupt Healthcare Systems: The Bosnian Example

    PubMed Central

    Neerup Handlos, Line; Fog Olwig, Karen; Bygbjerg, Ib Christian; Norredam, Marie

    2016-01-01

    Equal and universal access to healthcare services is a core priority for a just health system. A key societal determinant seen to create inequality in access to healthcare is corruption in the healthcare system. How return migrants’ access to healthcare is affected by corruption is largely unstudied, even though return migrants may be particularly vulnerable to problems related to corruption due to their period of absence from their country of origin. This article investigates how corruption in the healthcare sector affects access to healthcare for refugees who repatriated to Bosnia, a country with a high level of corruption, from Denmark, a country with a low level of corruption. The study is based on 18 semi-structured interviews with 33 refugees who returned after long-term residence in Denmark. We found that the returned refugees faced greater problems with corruption than was the case for those who had not left the country, as doctors considered them to be better endowed financially and therefore demanded larger bribes from them than they did from those who had remained in Bosnia. Moreover, during their stay abroad the returnees had lost the connections that could have helped them sidestep the corruption. Returned refugees are thus particularly vulnerable to the effects of corruption. PMID:27657096

  4. Effects of reduced return activated sludge flows and volume on anaerobic zone performance for a septic wastewater biological phosphorus removal system.

    PubMed

    Magro, Daniel; Elias, Steven L; Randall, Andrew Amis

    2005-01-01

    Enhanced biological phosphorous removal (EBPR) performance was found to be adequate with reduced return-activated sludge (RAS) flows (50% of available RAS) to the anaerobic tank and smaller-than-typical anaerobic zone volume (1.08 hours hydraulic retention time [HRT]). Three identical parallel biological nutrient removal pilot plants were fed with strong, highly fermented (160 mg/L volatile fatty acids [VFAs]), domestic and industrial wastewater from a full-scale wastewater treatment facility. The pilot plants were operated at 100, 50, 40, and 25% RAS (percent of available RAS) flows to the anaerobic tank, with the remaining RAS to the anoxic tank. In addition, varying anaerobic HRT (1.08 and 1.5 hours) and increased hydraulic loading (35% increase) were examined. The study was divided into four phases, and the effect of these process variations on EBPR were studied by having one different variable between two identical systems. The most significant conclusion was that returning part of the RAS to the anaerobic zone did not decrease EBPR performance; instead, it changed the location of phosphorous release and uptake. Bringing less RAS to the anaerobic and more to the anoxic tank decreased anaerobic phosphorus release and increased anoxic phosphorus release (or decreased anoxic phosphorus uptake). Equally important is that, with VFA-rich influent wastewater, excessive anaerobic volume was shown to hurt overall phosphorus removal, even when it resulted in increased anaerobic phosphorus release.

  5. 19 CFR 171.51 - Application and definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... hallucinogin or a cannabis-controlled substance will be considered in excess of personal use quantities if the... leaves, except coca leaves and extracts of coca leaves from which cocaine, ecgonine, and derivations of...

  6. 19 CFR 171.51 - Application and definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... hallucinogin or a cannabis-controlled substance will be considered in excess of personal use quantities if the... leaves, except coca leaves and extracts of coca leaves from which cocaine, ecgonine, and derivations of...

  7. 19 CFR 171.51 - Application and definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... hallucinogin or a cannabis-controlled substance will be considered in excess of personal use quantities if the... leaves, except coca leaves and extracts of coca leaves from which cocaine, ecgonine, and derivations of...

  8. Performance Improvement of a Return Channel in a Multistage Centrifugal Compressor Using Multiobjective Optimization.

    PubMed

    Nishida, Yoshifumi; Kobayashi, Hiromi; Nishida, Hideo; Sugimura, Kazuyuki

    2013-05-01

    The effect of the design parameters of a return channel on the performance of a multistage centrifugal compressor was numerically investigated, and the shape of the return channel was optimized using a multiobjective optimization method based on a genetic algorithm to improve the performance of the centrifugal compressor. The results of sensitivity analysis using Latin hypercube sampling suggested that the inlet-to-outlet area ratio of the return vane affected the total pressure loss in the return channel, and that the inlet-to-outlet radius ratio of the return vane affected the outlet flow angle from the return vane. Moreover, this analysis suggested that the number of return vanes affected both the loss and the flow angle at the outlet. As a result of optimization, the number of return vane was increased from 14 to 22 and the area ratio was decreased from 0.71 to 0.66. The radius ratio was also decreased from 2.1 to 2.0. Performance tests on a centrifugal compressor with two return channels (the original design and optimized design) were carried out using two-stage test apparatus. The measured flow distribution exhibited a swirl flow in the center region and a reversed swirl flow near the hub and shroud sides. The exit flow of the optimized design was more uniform than that of the original design. For the optimized design, the overall two-stage efficiency and pressure coefficient were increased by 0.7% and 1.5%, respectively. Moreover, the second-stage efficiency and pressure coefficient were respectively increased by 1.0% and 3.2%. It is considered that the increase in the second-stage efficiency was caused by the increased uniformity of the flow, and the rise in the pressure coefficient was caused by a decrease in the residual swirl flow. It was thus concluded from the numerical and experimental results that the optimized return channel improved the performance of the multistage centrifugal compressor.

  9. Hadron-rich cosmic-ray families detected by emulsion chamber.

    NASA Astrophysics Data System (ADS)

    Navia, C. E.; Augusto, C. R. K.; Pinto, F. A.; Shibuya, H.

    1995-11-01

    Observed hadrons in excess, larger-than-expected charged mesons (pions) in cosmic-ray families detected in emulsion chamber experiment at mountain altitude and produced in a cosmic-ray hadronic interaction not far from the PeV energy region are studied. The hypothesis that these extra hadrons could be a bundle of surviving nuclear fragments (nucleons) is verified through a simulation method using a hybrid code composed of a superposition model to describe the number of interacting nucleon-nucleon pairs in a nucleus-nucleus collision. Together with the UA5 algorithm to describe a nucleon-nucleon collision, atmospheric propagation structure is also considered. A comparison between simulation output with experimental data shows that the surviving-nuclear-fragments hypothesis is not enough to explain the non-pionic hadron excess, even if a heavy dominance composition in the primary flux is considered.

  10. Schooling Location and Economic, Occupational and Cognitive Success among Immigrants and Their Children: The Case of Los Angeles*

    PubMed Central

    Jackson, Margot I.; Pebley, Anne R.; Goldman, Noreen

    2010-01-01

    Large numbers of foreign-born residents in the United States mean that many people receive at least part of their education abroad. Despite this fact, our understanding of nativity differences in the success of adults and their children is based on research that does not empirically consider variation in the benefits to schooling depending on where it is received. We use data from the Los Angeles Family and Neighborhood Survey (L.A. FANS) to examine: a) whether the socioeconomic and cognitive returns to education depend on whether it is received in the U.S. or abroad; and b) whether schooling location partially accounts for nativity differences in these returns. We find that the returns to schooling are generally largest for adults who receive at least some of their highest level of education in the U.S. The beneficial effects of U.S. schooling are more pronounced at higher levels of educational attainment. Schooling location accounts for a sizeable fraction of the lower socioeconomic and cognitive returns of the foreign-born, relative to natives; some meaningful differences remain, however. In addition, the higher cognitive skills of the children of foreign-born adults remain unexplained. Although we cannot distinguish among the possible pathways underlying these associations (e.g., school quality, transferability of credentials, the timing of immigration) our findings suggest the importance of considering factors related to schooling location as predictors of socioeconomic and cognitive success in the United States. PMID:23436949

  11. A new framing approach in guideline development to manage different sources of knowledge.

    PubMed

    Lukersmith, Sue; Hopman, Katherine; Vine, Kristina; Krahe, Lee; McColl, Alexander

    2017-02-01

    Contemporary guideline methodology struggles to consider context and information from different sources of knowledge besides quantitative research. Return to work programmes involve multiple components and stakeholders. If the guideline is to be relevant and practical for a complex intervention such as return to work, it is essential to use broad sources of knowledge. This paper reports on a new method in guideline development to manage different sources of knowledge. The method used framing for the return-to-work guidance within the Clinical Practice Guidelines for the Management of Rotator Cuff Syndrome in the Workplace. The development involved was a multi-disciplinary working party of experts including consumers. The researchers considered a broad range of research, expert (practice and experience) knowledge, the individual's and workplace contexts, and used framing with the International Classification of Functioning, Disability and Health. Following a systematic database search on four clinical questions, there were seven stages of knowledge management to extract, unpack, map and pack information to the ICF domains framework. Companion graded recommendations were developed. The results include practical examples, user and consumer guides, flow charts and six graded or consensus recommendations on best practice for return to work intervention. Our findings suggest using framing in guideline methodology with internationally accepted frames such as the ICF is a reliable and transparent framework to manage different sources of knowledge. Future research might examine other examples and methods for managing complexity and using different sources of knowledge in guideline development. © 2016 John Wiley & Sons, Ltd.

  12. Uncertainty Analysis of Air Radiation for Lunar Return Shock Layers

    NASA Technical Reports Server (NTRS)

    Kleb, Bil; Johnston, Christopher O.

    2008-01-01

    By leveraging a new uncertainty markup technique, two risk analysis methods are used to compute the uncertainty of lunar-return shock layer radiation predicted by the High temperature Aerothermodynamic Radiation Algorithm (HARA). The effects of epistemic uncertainty, or uncertainty due to a lack of knowledge, is considered for the following modeling parameters: atomic line oscillator strengths, atomic line Stark broadening widths, atomic photoionization cross sections, negative ion photodetachment cross sections, molecular bands oscillator strengths, and electron impact excitation rates. First, a simplified shock layer problem consisting of two constant-property equilibrium layers is considered. The results of this simplified problem show that the atomic nitrogen oscillator strengths and Stark broadening widths in both the vacuum ultraviolet and infrared spectral regions, along with the negative ion continuum, are the dominant uncertainty contributors. Next, three variable property stagnation-line shock layer cases are analyzed: a typical lunar return case and two Fire II cases. For the near-equilibrium lunar return and Fire 1643-second cases, the resulting uncertainties are very similar to the simplified case. Conversely, the relatively nonequilibrium 1636-second case shows significantly larger influence from electron impact excitation rates of both atoms and molecules. For all cases, the total uncertainty in radiative heat flux to the wall due to epistemic uncertainty in modeling parameters is 30% as opposed to the erroneously-small uncertainty levels (plus or minus 6%) found when treating model parameter uncertainties as aleatory (due to chance) instead of epistemic (due to lack of knowledge).

  13. Internet Addiction and Excessive Social Networks Use: What About Facebook?

    PubMed Central

    Guedes, Eduardo; Sancassiani, Federica; Carta, Mauro Giovani; Campos, Carlos; Machado, Sergio; King, Anna Lucia Spear; Nardi, Antonio Egidio

    2016-01-01

    Facebook is notably the most widely known and used social network worldwide. It has been described as a valuable tool for leisure and communication between people all over the world. However, healthy and conscience Facebook use is contrasted by excessive use and lack of control, creating an addiction with severely impacts the everyday life of many users, mainly youths. If Facebook use seems to be related to the need to belong, affiliate with others and for self-presentation, the beginning of excessive Facebook use and addiction could be associated to reward and gratification mechanisms as well as some personality traits. Studies from several countries indicate different Facebook addiction prevalence rates, mainly due to the use of a wide-range of evaluation instruments and to the lack of a clear and valid definition of this construct. Further investigations are needed to establish if excessive Facebook use can be considered as a specific online addiction disorder or an Internet addiction subtype. PMID:27418940

  14. Internet Addiction and Excessive Social Networks Use: What About Facebook?

    PubMed

    Guedes, Eduardo; Sancassiani, Federica; Carta, Mauro Giovani; Campos, Carlos; Machado, Sergio; King, Anna Lucia Spear; Nardi, Antonio Egidio

    2016-01-01

    Facebook is notably the most widely known and used social network worldwide. It has been described as a valuable tool for leisure and communication between people all over the world. However, healthy and conscience Facebook use is contrasted by excessive use and lack of control, creating an addiction with severely impacts the everyday life of many users, mainly youths. If Facebook use seems to be related to the need to belong, affiliate with others and for self-presentation, the beginning of excessive Facebook use and addiction could be associated to reward and gratification mechanisms as well as some personality traits. Studies from several countries indicate different Facebook addiction prevalence rates, mainly due to the use of a wide-range of evaluation instruments and to the lack of a clear and valid definition of this construct. Further investigations are needed to establish if excessive Facebook use can be considered as a specific online addiction disorder or an Internet addiction subtype.

  15. Excess current experiment on YBCO tape conductor with metal stabilized layer

    NASA Astrophysics Data System (ADS)

    Tasaki, Kenji; Yazawa, Takashi; Ono, Michitaka; Kuriyama, Toru

    2006-06-01

    Excess current experiments were performed using YBCO tape conductors with a metal stabilized layer on the superconducting layer. The purpose of this research is to obtain the stable criteria of energy dissipation when YBCO tape is forced to flow excess current higher than its critical current. This situation should be considered in power applications. In the experiments short-length samples were immersed in liquid nitrogen and several cycles of 50Hz sinusoidal current were supplied to the samples by an induction voltage regulator. The critical current of the samples was about 110 A. With pulse length as long as 60 ms, YBCO tapes were able to be energized up to twelve times as the critical current without electrical or mechanical deformation. Prior to the excess current experiments, temperature dependency of resistance of the sample was measured so that the temperature rise was estimated by the generated resistance. It is found that YBCO tapes with a copper stabilized layer can be transiently heated to over 400K without degradation.

  16. Abnormal excessive per vagina (PV) bleeding on Esmya–selective progesterone receptor modulator (SPRM) in a symptomatic patient with uterine fibroid

    PubMed Central

    Matytsina-Quinlan, Lyubov; Matytsina, Laura

    2015-01-01

    A woman in her late 40s presented with excessive per vagina (PV) bleeding and uterine fibroid. She reported excessive PV bleeding after starting Esmya; she was brought in by ambulance to the emergency department with profuse bleeding. Abnormal uterine bleeding (AUB) developed after selective progesterone receptor modulator (SPRM) administration in this symptomatic patient with uterine fibroid. The drug was withheld and surgical treatment considered. Progressive deterioration of PV bleeding after receiving SPRM led to an urgent laparoscopic total hysterectomy, which had to be postponed due to severe anaemia. Surgery took place regardless because the excessive bleeding continued. Histology revealed a 6 cm submucosal uterine fibroid (SMUF) and adenomyosis. Physicians prescribing SPRMs to stop PV bleeding should be aware of potential AUB, which could lead to urgent hysterectomy. The mechanism of action of SPRMs is not clearly understood. Awareness of the side effects of Esmya, such as AUB, must be kept in mind when administering SPRMs. PMID:25976198

  17. Abnormal excessive per vagina (PV) bleeding on Esmya-selective progesterone receptor modulator (SPRM) in a symptomatic patient with uterine fibroid.

    PubMed

    Matytsina-Quinlan, Lyubov; Matytsina, Laura

    2015-05-14

    A woman in her late 40s presented with excessive per vagina (PV) bleeding and uterine fibroid. She reported excessive PV bleeding after starting Esmya; she was brought in by ambulance to the emergency department with profuse bleeding. Abnormal uterine bleeding (AUB) developed after selective progesterone receptor modulator (SPRM) administration in this symptomatic patient with uterine fibroid. The drug was withheld and surgical treatment considered. Progressive deterioration of PV bleeding after receiving SPRM led to an urgent laparoscopic total hysterectomy, which had to be postponed due to severe anaemia. Surgery took place regardless because the excessive bleeding continued. Histology revealed a 6 cm submucosal uterine fibroid (SMUF) and adenomyosis. Physicians prescribing SPRMs to stop PV bleeding should be aware of potential AUB, which could lead to urgent hysterectomy. The mechanism of action of SPRMs is not clearly understood. Awareness of the side effects of Esmya, such as AUB, must be kept in mind when administering SPRMs. 2015 BMJ Publishing Group Ltd.

  18. H α VARIABILITY IN PTFO 8-8695 AND THE POSSIBLE DIRECT DETECTION OF EMISSION FROM A 2 MILLION YEAR OLD EVAPORATING HOT JUPITER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johns-Krull, Christopher M.; Chen, Wei; Frazier, Sarah A., E-mail: cmj@rice.edu, E-mail: wc2@rice.edu, E-mail: sarah.a.frazier@rice.edu

    We use high time cadence, high spectral resolution optical observations to detect excess H α emission from the 2–3 Myr old weak-lined T Tauri star PTFO 8-8695. This excess emission appears to move in velocity as expected if it were produced by the suspected planetary companion to this young star. The excess emission is not always present, but when it is, the predicted velocity motion is often observed. We have considered the possibility that the observed excess emission is produced by stellar activity (flares), accretion from a disk, or a planetary companion; we find the planetary companion to be themore » most likely explanation. If this is the case, the strength of the H α line indicates that the emission comes from an extended volume around the planet, likely fed by mass loss from the planet which is expected to be overflowing its Roche lobe.« less

  19. Excess current in ferromagnet-superconductor structures with fully polarized triplet component

    NASA Astrophysics Data System (ADS)

    Moor, Andreas; Volkov, Anatoly F.; Efetov, Konstantin B.

    2016-05-01

    We study the I -V characteristics of ST/n/N contacts, where ST is a BCS superconductor S with a built-in exchange field h , n represents a normal metal wire, and N a normal metal reservoir. The superconductor ST is separated from the n wire by a spin filter which allows the passage of electrons with a certain spin direction so that only fully polarized triplet Cooper pairs penetrate into the n wire. We show that both the subgap conductance σsg and the excess current Iexc, which occur in conventional S/n/N contacts due to Andreev reflection (AR), exist also in the considered system. In our case, they are caused by unconventional AR that is not accompanied by spin flip. The excess current Iexc exists only if h exceeds a certain magnitude hc. At h

  20. Livestock mortality in pastoralist herds in Ethiopia and implications for drought response.

    PubMed

    Catley, Andy; Admassu, Berhanu; Bekele, Gezu; Abebe, Dawit

    2014-07-01

    Participatory epidemiology methods were employed retrospectively in three pastoralist regions of Ethiopia to estimate the specific causes of excess livestock mortality during drought. The results showed that starvation/dehydration accounted for between 61.5 and 100 per cent of excess livestock mortality during drought, whereas disease-related mortality accounted for between 0 and 28.1 per cent of excess mortality. Field observations indicate that, in livestock, disease risks and mortality increase in the immediate post-drought period, during rain. The design of livelihoods-based drought response programmes should include protection of core livestock assets, and it should take account of the specific causes of excess livestock mortality during drought and immediately afterwards. This study shows that, when comparing livestock feed supplementation and veterinary support, relatively more aid should be directed at the former if the objective is to protect core livestock during drought. Veterinary support should consider disease-related mortality in the immediate post-drought period, and tailor inputs accordingly. © 2014 The Author(s). Disasters © Overseas Development Institute, 2014.

  1. Ambient pressure fuel cell system

    DOEpatents

    Wilson, Mahlon S.

    2000-01-01

    An ambient pressure fuel cell system is provided with a fuel cell stack formed from a plurality of fuel cells having membrane/electrode assemblies (MEAs) that are hydrated with liquid water and bipolar plates with anode and cathode sides for distributing hydrogen fuel gas and water to a first side of each one of the MEAs and air with reactant oxygen gas to a second side of each one of the MEAs. A pump supplies liquid water to the fuel cells. A recirculating system may be used to return unused hydrogen fuel gas to the stack. A near-ambient pressure blower blows air through the fuel cell stack in excess of reaction stoichiometric amounts to react with the hydrogen fuel gas.

  2. Down-flow moving-bed gasifier with catalyst recycle

    DOEpatents

    Halow, J.S.

    1999-04-20

    The gasification of coal and other carbonaceous materials by an endothermic gasification reaction is achieved in the presence of a catalyst in a down-flow, moving-bed gasifier. Catalyst is removed along with ash from the gasifier and is then sufficiently heated in a riser/burner by the combustion of residual carbon in the ash to volatilize the catalyst. This volatilized catalyst is returned to the gasifier where it uniformly contacts and condenses on the carbonaceous material. Also, the hot gaseous combustion products resulting from the combustion of the carbon in the ash along with excess air are introduced into the gasifier for providing heat energy used in the endothermic reaction. 1 fig.

  3. High-Output Heart Failure Caused by Thyrotoxicosis and Beriberi.

    PubMed

    McCulloch, Brenda

    2015-12-01

    High-output heart failure is not seen as commonly as low-output heart failure and some of the typical guideline recommendations may not benefit patients with high-output failure. High-output failure is caused by several diseases, including thyrotoxicosis and beriberi, highlighted in this article. Thyrotoxicosis, caused by excessive thyroid hormone production, has profound hemodynamic effects. Wet beriberi, affecting predominately the cardiovascular system, is caused by severe thiamine deficiency, most commonly seen in patients with chronic alcoholism or poor nutrition from other causes. Prompt recognition of these infrequently seen syndromes is essential. This article outlines the medical treatment and nursing care needed to return these patients to a normal state. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Engineering evaluations and studies. Report for Ku-band studies, exhibit A

    NASA Technical Reports Server (NTRS)

    Dodds, J. G.; Huth, G. K.; Maronde, R. G.; Roberts, D.

    1981-01-01

    System performance aspects of the Ku band radar communication hardware and investigations into the Ku band/payload interfaces are discussed. The communications track problem caused by the excessive signal dynamic range at the servo input was investigated. The management/handover logic is discussed and a simplified description of the transmitter enable logic function is presented. Output noise produced by a voltage-controlled oscillator chip used in the SPA return-link channel 3 mid-bit detector is discussed. The deployed assembly (DA) and EA-2 critical design review data are evaluated. Cross coupling effects on antenna servo stability were examined. A series of meetings on the acceptance test specification for the deployed assembly is summarized.

  5. ERROR REDUCTION IN DUCT LEAKAGE TESTING THROUGH DATA CROSS-CHECKS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    ANDREWS, J.W.

    1998-12-31

    One way to reduce uncertainty in scientific measurement is to devise a protocol in which more quantities are measured than are absolutely required, so that the result is over constrained. This report develops a method for so combining data from two different tests for air leakage in residential duct systems. An algorithm, which depends on the uncertainty estimates for the measured quantities, optimizes the use of the excess data. In many cases it can significantly reduce the error bar on at least one of the two measured duct leakage rates (supply or return), and it provides a rational method ofmore » reconciling any conflicting results from the two leakage tests.« less

  6. Stylized facts from a threshold-based heterogeneous agent model

    NASA Astrophysics Data System (ADS)

    Cross, R.; Grinfeld, M.; Lamba, H.; Seaman, T.

    2007-05-01

    A class of heterogeneous agent models is investigated where investors switch trading position whenever their motivation to do so exceeds some critical threshold. These motivations can be psychological in nature or reflect behaviour suggested by the efficient market hypothesis (EMH). By introducing different propensities into a baseline model that displays EMH behaviour, one can attempt to isolate their effects upon the market dynamics. The simulation results indicate that the introduction of a herding propensity results in excess kurtosis and power-law decay consistent with those observed in actual return distributions, but not in significant long-term volatility correlations. Possible alternatives for introducing such long-term volatility correlations are then identified and discussed.

  7. Attitudes and intentions of current anaesthetic trainees.

    PubMed

    Fröhlich, S; Moriarty, J

    2013-03-01

    We report the results of a survey of Irish anaesthetic specialist trainees to establish their future training intentions, their interest in seeking a Consultant position in Ireland and identification of factors that may reduce the attractiveness of future employment in the HSE. 149 responses were received (71% of trainees). 137 (92%) are likely to complete further training abroad, but only 24 (16.1%) are definitely planning to return to work in Ireland. Factors, in order of importance that influence their return to Ireland include equivalence of all Consultants, salary level and availability of flexible work practices. Almost all (131 - 91%) would only consider working in Ireland at Consultant level. These results reveal that the current cohort of specialist trainees do not consider Ireland an attractive place to work, and any further diminution of the current Consultant grade will only serve to worsen this perception.

  8. Adding insult to injury?: the untoward impact of requiring more than de minimis injury in an Eighth Amendment excessive force case.

    PubMed

    Hoffman, Robyn D

    2009-05-01

    This Note explores the conflict over whether a prisoner must suffer more than de minimis injury to sustain an Eighth Amendment excessive force claim. It examines this conflict against the backdrop of the various standards the U.S. Supreme Court adopted in its Eighth Amendment prison conditions jurisprudence between 1976 and 1992, principally focusing on the 1992 Hudson v. McMillian decision. Moreover, this Note considers the intersection of "the evolving standards of decency," the "hands-off doctrine," and the Eighth Amendment injury requirement. Ultimately, this Note advocates that excessive force--when meted out as punishment--violates the Eighth Amendment's prohibition on cruel and unusual punishment regardless of whether a prisoner's injuries are more than de minimis.

  9. Is the CMS e e j j excess a hint for light supersymmetry?

    NASA Astrophysics Data System (ADS)

    Krauss, Manuel E.; Porod, Werner

    2015-09-01

    We discuss the impact of additional two-body decays of the right-handed neutrino into a light charged Higgs state on the dilepton plus dijet cross sections from resonant W' production. We consider in particular a supersymmetric left-right symmetric model which predicts such a light charged Higgs boson. We demonstrate that the e e j j excess as measured by CMS can be explained best if the W' also has decay modes into Higgsino-like charginos and neutralinos with masses of a few hundred GeV. Provided that this excess is confirmed, the model predicts also one right-handed neutrino with a mass below 200 GeV as well as a doubly charged Higgs boson which should be discovered at the LHC in the near future.

  10. Observation of incomplete drainage of a branched negative stepped leader system during the initial return stroke, and its implications

    NASA Astrophysics Data System (ADS)

    Petersen, D.; Beasley, W. H.

    2012-12-01

    We present high-speed video, taken at 75,000 frames per second, of an anomalous lightning flash that involved two distinct return strokes from different branches of the same branched negative stepped leader system. During the initial return stroke the leader system was incompletely drained, resulting in the continued development of a large side branch. The upper portions of this side branch exhibited a pulse of luminosity during the initial return stroke, but the luminosity did not extend down the branch. The lower portion of the branch continued to develop downward as a negative stepped leader, but at a much slower velocity. Continued stepping activity was observed in this branch as it continued downward at a significantly reduced velocity, finally attaching to the earth 1.8 milliseconds after the main return stroke. The ensuing return stroke was characterized by a slower vertical velocity and weaker luminous pulse. Based on this observation, we coin the term "orphaned branch" to describe a branch of a leader system that is not drained during a return stroke. While our case involves a branch that eventually connected to the ground and produced a return stroke, we also consider the possibility that such branches may also simply cease to progress and effectively deposit large amounts of space charge near their extremities. Such space charge would have a strong influence on subsequent breakdown activity in their vicinity, such as shielding subsequent descending negative stepped leaders or triggering upward positive leaders from earth's surface.

  11. The dual effect of vegetation green-up date and strong wind on the return period of spring dust storms.

    PubMed

    Feng, Jieling; Li, Ning; Zhang, Zhengtao; Chen, Xi

    2017-08-15

    Vegetation phenology changes have been widely applied in the disaster risk assessments of the spring dust storms, and vegetation green-up date shifts have a strong influence on dust storms. However, the effect of earlier vegetation green-up dates due to climate warming on the evaluation of dust storms return periods remains an important, but poorly understood issue. In this study, we evaluate the spring dust storm return period (February to June) in Inner Mongolia, Northern China, using 165 observations of severe spring dust storm events from 16 weather stations, and regional vegetation green-up dates as an integrated factor from NDVI (Normalized Difference Vegetation Index), covering a period from 1982 to 2007, by building the bivariate Copula model. We found that the joint return period showed better fitting results than without considering the integrated factor when the actual dust storm return period is longer than 2years. Also, for extremely severe dust storm events, the gap between simulation result and actual return period can be narrowed up to 0.4888years by using integrated factor. Furthermore, the risk map based on the return period results shows that the Mandula, Zhurihe, Sunitezuoqi, Narenbaolige stations are identified as high risk areas. In this study area, land surface is extensively covered by grasses and shrubs, vegetation green-up date can play a significant role in restraining spring dust storm outbreaks. Therefore, we suggest that Copula method can become a useful tool for joint return period evaluation and risk analysis of severe dust storms. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Return of Genomic Results to Research Participants: The Floor, the Ceiling, and the Choices In Between

    PubMed Central

    Jarvik, Gail P.; Amendola, Laura M.; Berg, Jonathan S.; Brothers, Kyle; Clayton, Ellen W.; Chung, Wendy; Evans, Barbara J.; Evans, James P.; Fullerton, Stephanie M.; Gallego, Carlos J.; Garrison, Nanibaa’ A.; Gray, Stacy W.; Holm, Ingrid A.; Kullo, Iftikhar J.; Lehmann, Lisa Soleymani; McCarty, Cathy; Prows, Cynthia A.; Rehm, Heidi L.; Sharp, Richard R.; Salama, Joseph; Sanderson, Saskia; Van Driest, Sara L.; Williams, Marc S.; Wolf, Susan M.; Wolf, Wendy A.; Harley, John; Myers, Melanie; Namjou, Bahram; Vinks, Sander; Connolly, John; Keating, Brendan; Gerhard, Glenn; Sundaresan, Agnes; Tromp, Gerard; Crosslin, David; Leppig, Kathy; Wicklund, Cathy; Chute, Christopher; Lynch, John; De Andrade, Mariza; Heit, John; McCormick, Jen; Brilliant, Murray; Kitchner, Terrie; Ritchie, Marylyn; Böttinger, Erwin; Peter, Inga; Persell, Stephen; Rasmussen-Torvik, Laura; McGregor, Tracy; Roden, Dan; Antommaria, Armand; Chiavacci, Rosetta; Faucett, Andy; Ledbetter, David; Williams, Janet; Hartzler, Andrea; Vitek, Carolyn R. Rohrer; Frost, Norm; Ferryman, Kadija; Horowitz, Carol; Rhodes, Rosamond; Zinberg, Randi; Aufox, Sharon; Pan, Vivian; Long, Rochelle; Ramos, Erin; Odgis, Jackie; Wise, Anastasia; Hull, Sara; Gitlin, Jonathan; Green, Robert; Metterville, Danielle; McGuire, Amy; Kong, Sek Won; Trinidad, Sue; Veenstra, David; Roche, Myra; Skinner, Debra; Raspberry, Kelly; O’Daniel, Julianne; Parsons, Will; Eng, Christine; Hilsenbeck, Susan; Karavite, Dean; Conlin, Laura; Spinner, Nancy; Krantz, Ian; Falk, Marni; Santani, Avni; Dechene, Elizabeth; Dulik, Matthew; Bernhardt, Barbara; Schuetze, Scott; Everett, Jessica; Gornick, Michele Caroline; Wilfond, Ben; Tabor, Holly; Lemke, Amy A.; Richards, Sue; Goddard, Katrina; Cooper, Greg; East, Kelly; Barsh, Greg; Koenig, Barbara; Van Allen, Eliezer; Garber, Judy; Garrett, Jeremy; Zawati, Ma’n; Lewis, Michelle; Savage, Sarah; Smith, Maureen; Roychowdhury, Sameek; Bailey, Alice; Berkman, Benjamin; Anan, Charlisse Caga; Hindorff, Lucia; Hutter, Carolyn; King, Rosalind; Li, Rongling; Lockhart, Nicole; McEwen, Jean; Scholes, Derek; Schully, Sheri; Sun, Kathie; Burke, Wylie

    2014-01-01

    As more research studies incorporate next-generation sequencing (including whole-genome or whole-exome sequencing), investigators and institutional review boards face difficult questions regarding which genomic results to return to research participants and how. An American College of Medical Genetics and Genomics 2013 policy paper suggesting that pathogenic mutations in 56 specified genes should be returned in the clinical setting has raised the question of whether comparable recommendations should be considered in research settings. The Clinical Sequencing Exploratory Research (CSER) Consortium and the Electronic Medical Records and Genomics (eMERGE) Network are multisite research programs that aim to develop practical strategies for addressing questions concerning the return of results in genomic research. CSER and eMERGE committees have identified areas of consensus regarding the return of genomic results to research participants. In most circumstances, if results meet an actionability threshold for return and the research participant has consented to return, genomic results, along with referral for appropriate clinical follow-up, should be offered to participants. However, participants have a right to decline the receipt of genomic results, even when doing so might be viewed as a threat to the participants’ health. Research investigators should be prepared to return research results and incidental findings discovered in the course of their research and meeting an actionability threshold, but they have no ethical obligation to actively search for such results. These positions are consistent with the recognition that clinical research is distinct from medical care in both its aims and its guiding moral principles. PMID:24814192

  13. Analysis of intrapulse chirp in CO2 oscillators

    NASA Technical Reports Server (NTRS)

    Moody, Stephen E.; Berger, Russell G.; Thayer, William J., III

    1987-01-01

    Pulsed single-frequency CO2 laser oscillators are often used as transmitters for coherent lidar applications. These oscillators suffer from intrapulse chirp, or dynamic frequency shifting. If excessive, such chirp can limit the signal-to-noise ratio of the lidar (by generating excess bandwidth), or limit the velocity resolution if the lidar is of the Doppler type. This paper describes a detailed numerical model that considers all known sources of intrapulse chirp. Some typical predictions of the model are shown, and simple design rules to minimize chirp are proposed.

  14. Bridging the gap between health and non-health investments: moving from cost-effectiveness analysis to a return on investment approach across sectors of economy.

    PubMed

    Sendi, Pedram

    2008-06-01

    When choosing from a menu of treatment alternatives, the optimal treatment depends on the objective function and the assumptions of the model. The classical decision rule of cost-effectiveness analysis may be formulated via two different objective functions: (i) maximising health outcomes subject to the budget constraint or (ii) maximising the net benefit of the intervention with the budget being determined ex post. We suggest a more general objective function of (iii) maximising return on investment from available resources with consideration of health and non-health investments. The return on investment approach allows to adjust the analysis for the benefits forgone by alternative non-health investments from a societal or subsocietal perspective. We show that in the presence of positive returns on non-health investments the decision-maker's willingness to pay per unit of effect for a treatment program needs to be higher than its incremental cost-effectiveness ratio to be considered cost-effective.

  15. Stakeholder views on returning research results.

    PubMed

    Haga, Susanne B; Zhao, Jennifer Q

    2013-01-01

    While the disclosure of research findings is relevant to all types of biomedical research, it has garnered particular attention with respect to genetics and genomics research due to some of the unique aspects of the data and the high public profile of the field. In this chapter, we review the attitudes of stakeholders (research participants, policymakers, and researchers) to define areas of consensus regarding the issue of returning research results across and within groups. In addition to stakeholder attitudes about obligations and interest in research results, other major related issues related to returning research results, such as informed consent, communication of research results, and cost, are discussed. Given the consensus between stakeholders to return summary reports of a study's outcomes and individual research results of clinical significance, we conclude that the time has come to encourage, if not require, researchers to consider these issues in the developmental planning stages of a project and to plan and budget accordingly. © 2013 Elsevier Inc. All rights reserved.

  16. Planning Considerations Related to Collecting and Analyzing Samples of the Martian Soils

    NASA Technical Reports Server (NTRS)

    Liu, Yang; Mellon, Mike T.; Ming, Douglas W.; Morris, Richard V.; Noble, Sarah K.; Sullivan, Robert J.; Taylor, Lawrence A.; Beaty, David W.

    2014-01-01

    The Mars Sample Return (MSR) End-to-End International Science Analysis Group (E2E-iSAG [1]) established scientific objectives associ-ated with Mars returned-sample science that require the return and investigation of one or more soil samples. Soil is defined here as loose, unconsolidated materials with no implication for the presence or absence of or-ganic components. The proposed Mars 2020 (M-2020) rover is likely to collect and cache soil in addition to rock samples [2], which could be followed by future sample retrieval and return missions. Here we discuss key scientific consid-erations for sampling and caching soil samples on the proposed M-2020 rover, as well as the state in which samples would need to be preserved when received by analysts on Earth. We are seeking feedback on these draft plans as input to mission requirement formulation. A related planning exercise on rocks is reported in an accompanying abstract [3].

  17. Effects of personality on overtime work: a cross-sectional pilot study among Japanese white-collar workers

    PubMed Central

    2014-01-01

    Background As detailed associations between personality and long work hours are unclear, we assessed associations between personality dimensions and overtime work among Japanese white-collar workers. Methods From records of hours worked over 12 months by 267 office workers in an organization within the service industry, average overtime work hours per month and occurrence of excessive overtime was determined for each worker. Excessive overtime was defined as >  45 overtime work hours per month for at least one month. Responses to a questionnaire assessing socio-demographic and workplace-related factors and the Big Five personality test were analyzed. Associations between personality factors and overtime work were assessed by multivariate logistic regression analysis. Results Low Extraversion was associated with excessive overtime work (OR 2.02, 95%CI 1.02 – 4.02, P =  0.04). Conclusions It is suggested that workers with low Extraversion can’t share work when busy to avoid excessive overtime. Personality factors should be considered in studies evaluating work time. Moreover, strengthening communication among workers with low Extraversion may reduce excessive overtime work and associated health problems. PMID:24670102

  18. Search for an Excess of Events in the Super-Kamiokande Detector in the Directions of the Astrophysical Neutrinos Reported by the IceCube Collaboration

    NASA Astrophysics Data System (ADS)

    Abe, K.; Bronner, C.; Pronost, G.; Hayato, Y.; Ikeda, M.; Iyogi, K.; Kameda, J.; Kato, Y.; Kishimoto, Y.; Marti, Ll.; Miura, M.; Moriyama, S.; Nakahata, M.; Nakano, Y.; Nakayama, S.; Okajima, Y.; Orii, A.; Sekiya, H.; Shiozawa, M.; Sonoda, Y.; Takeda, A.; Takenaka, A.; Tanaka, H.; Tasaka, S.; Tomura, T.; Akutsu, R.; Kajita, T.; Kaneyuki, K.; Nishimura, Y.; Okumura, K.; Tsui, K. M.; Labarga, L.; Fernandez, P.; Blaszczyk, F. d. M.; Gustafson, J.; Kachulis, C.; Kearns, E.; Raaf, J. L.; Stone, J. L.; Sulak, L. R.; Berkman, S.; Tobayama, S.; Goldhaber, M.; Elnimr, M.; Kropp, W. R.; Mine, S.; Locke, S.; Weatherly, P.; Smy, M. B.; Sobel, H. W.; Takhistov, V.; Ganezer, K. S.; Hill, J.; Kim, J. Y.; Lim, I. T.; Park, R. G.; Himmel, A.; Li, Z.; O'Sullivan, E.; Scholberg, K.; Walter, C. W.; Ishizuka, T.; Nakamura, T.; Jang, J. S.; Choi, K.; Learned, J. G.; Matsuno, S.; Smith, S. N.; Amey, J.; Litchfield, R. P.; Ma, W. Y.; Uchida, Y.; Wascko, M. O.; Cao, S.; Friend, M.; Hasegawa, T.; Ishida, T.; Ishii, T.; Kobayashi, T.; Nakadaira, T.; Nakamura, K.; Oyama, Y.; Sakashita, K.; Sekiguchi, T.; Tsukamoto, T.; Abe, KE.; Hasegawa, M.; Suzuki, A. T.; Takeuchi, Y.; Yano, T.; Cao, S. V.; Hayashino, T.; Hiraki, T.; Hirota, S.; Huang, K.; Jiang, M.; Minamino, A.; Nakamura, KE.; Nakaya, T.; Quilain, B.; Patel, N. D.; Wendell, R. A.; Anthony, L. H. V.; McCauley, N.; Pritchard, A.; Fukuda, Y.; Itow, Y.; Murase, M.; Muto, F.; Mijakowski, P.; Frankiewicz, K.; Jung, C. K.; Li, X.; Palomino, J. L.; Santucci, G.; Vilela, C.; Wilking, M. J.; Yanagisawa, C.; Ito, S.; Fukuda, D.; Ishino, H.; Kibayashi, A.; Koshio, Y.; Nagata, H.; Sakuda, M.; Xu, C.; Kuno, Y.; Wark, D.; Di Lodovico, F.; Richards, B.; Tacik, R.; Kim, S. B.; Cole, A.; Thompson, L.; Okazawa, H.; Choi, Y.; Ito, K.; Nishijima, K.; Koshiba, M.; Totsuka, Y.; Suda, Y.; Yokoyama, M.; Calland, R. G.; Hartz, M.; Martens, K.; Simpson, C.; Suzuki, Y.; Vagins, M. R.; Hamabe, D.; Kuze, M.; Yoshida, T.; Ishitsuka, M.; Martin, J. F.; Nantais, C. M.; Tanaka, H. A.; Konaka, A.; Chen, S.; Wan, L.; Zhang, Y.; Minamino, A.; Wilkes, R. J.; Super-Kamiokande Collaboration

    2017-12-01

    We present the results of a search in the Super-Kamiokande (SK) detector for excesses of neutrinos with energies above a few GeV that are in the direction of the track events reported in IceCube. Data from all SK phases (SK-I through SK-IV) were used, spanning a period from 1996 April to 2016 April and corresponding to an exposure of 225 kiloton-years. We considered the 14 IceCube track events from a data set with 1347 livetime days taken from 2010 to 2014. We use Poisson counting to determine if there is an excess of neutrinos detected in SK in a 10° search cone (5° for the highest energy data set) around the reconstructed direction of the IceCube event. No significant excess was found in any of the search directions we examined. We also looked for coincidences with a recently reported IceCube multiplet event. No events were detected within a ±500 s time window around the first detected event, and no significant excess was seen from that direction over the lifetime of SK.

  19. Refractive Index Mixing Rules and Excess Infrared Spectra of Binary Mixtures.

    PubMed

    Baranović, Goran

    2017-05-01

    Three refractive index mixing rules, Arago-Biot, Lorentz-Lorenz, and Newton, are generalized to complex refractive index and used to define infrared (IR) spectra of the corresponding ideal liquid mixtures. Using the measured optical constants n and k for acetonitrile-water mixtures (Bertie and Lan, 1997) the excess absorbances, A E  =  A obs  -  A ideal , are calculated. Relying upon the well-established properties of the acetonitrile-water mixtures, the interpretation of the excess absorbances is established that is essentially based on the understanding of a liquid as a set of oscillators. The set depends on the composition of the mixture and comprises oscillators as present in the pure components and oscillators perturbed by hydrogen bonding between unlike molecules. The main features of an excess spectrum can be established assuming chemical equilibria among various oscillators. The most informative parts of the spectrum of a yet unstudied binary system can well be observed and even qualitatively explained from the excess absorbance provided: first, a detailed vibrational study of the components has been done; and, second, it is well understood what actually is subtracted from A obs . As examples, the binary mixtures of ethynylbenzene and tetrachloroethylene and 2-ethynylpyridine and tetrachloroethylene are considered.

  20. Guide to Understanding Hemangiomas

    MedlinePlus

    ... are similar to veins except they carry excess water instead of blood back to the heart. Lymphatics prevent swelling and are also part of the immune system. when should treatment for hemangiomas be considered? a ll physicians agree ...

  1. Ecuadorian Banana Farms Should Consider Organic Banana with Low Price Risks in Their Land-Use Portfolios

    PubMed Central

    Castro, Luz Maria; Calvas, Baltazar; Knoke, Thomas

    2015-01-01

    Organic farming is a more environmentally friendly form of land use than conventional agriculture. However, recent studies point out production tradeoffs that often prevent the adoption of such practices by farmers. Our study shows with the example of organic banana production in Ecuador that economic tradeoffs depend much on the approach of the analysis. We test, if organic banana should be included in economic land-use portfolios, which indicate how much of the land is provided for which type of land-use. We use time series data for productivity and prices over 30 years to compute the economic return (as annualized net present value) and its volatility (with standard deviation as risk measure) for eight crops to derive land-use portfolios for different levels of risk, which maximize economic return. We find that organic banana is included in land-use portfolios for almost every level of accepted risk with proportions from 1% to maximally 32%, even if the same high uncertainty as for conventional banana is simulated for organic banana. A more realistic, lower simulated price risk increased the proportion of organic banana substantially to up to 57% and increased annual economic returns by up to US$ 187 per ha. Under an assumed integration of both markets, for organic and conventional banana, simulated by an increased coefficient of correlation of economic return from organic and conventional banana (ρ up to +0.7), organic banana holds significant portions in the land-use portfolios tested only, if a low price risk of organic banana is considered. We conclude that uncertainty is a key issue for the adoption of organic banana. As historic data support a low price risk for organic banana compared to conventional banana, Ecuadorian farmers should consider organic banana as an advantageous land-use option in their land-use portfolios. PMID:25799506

  2. Ecuadorian banana farms should consider organic banana with low price risks in their land-use portfolios.

    PubMed

    Castro, Luz Maria; Calvas, Baltazar; Knoke, Thomas

    2015-01-01

    Organic farming is a more environmentally friendly form of land use than conventional agriculture. However, recent studies point out production tradeoffs that often prevent the adoption of such practices by farmers. Our study shows with the example of organic banana production in Ecuador that economic tradeoffs depend much on the approach of the analysis. We test, if organic banana should be included in economic land-use portfolios, which indicate how much of the land is provided for which type of land-use. We use time series data for productivity and prices over 30 years to compute the economic return (as annualized net present value) and its volatility (with standard deviation as risk measure) for eight crops to derive land-use portfolios for different levels of risk, which maximize economic return. We find that organic banana is included in land-use portfolios for almost every level of accepted risk with proportions from 1% to maximally 32%, even if the same high uncertainty as for conventional banana is simulated for organic banana. A more realistic, lower simulated price risk increased the proportion of organic banana substantially to up to 57% and increased annual economic returns by up to US$ 187 per ha. Under an assumed integration of both markets, for organic and conventional banana, simulated by an increased coefficient of correlation of economic return from organic and conventional banana (ρ up to +0.7), organic banana holds significant portions in the land-use portfolios tested only, if a low price risk of organic banana is considered. We conclude that uncertainty is a key issue for the adoption of organic banana. As historic data support a low price risk for organic banana compared to conventional banana, Ecuadorian farmers should consider organic banana as an advantageous land-use option in their land-use portfolios.

  3. Return to work after spinal cord injury: factors related to time to first job.

    PubMed

    Ramakrishnan, K; Mazlan, M; Julia, P E; Abdul Latif, L

    2011-08-01

    Cross-sectional survey. To investigate factors related to length of time between spinal cord injury (SCI) onset and start of first post-injury employment. Persons living with SCI in the community who are members of a disability support organization. Participants were randomly selected from the membership list of a non-governmental voluntary organization. They met the following four criteria: traumatic SCI, minimum of 15 years of age at the time of survey, a minimum of 2 years after SCI and had been employed for some time since SCI. The main outcome measure was time (in years) from injury onset to beginning first post-injury job. Participants averaged 4.9 years (s.d. 5.1) from the time of SCI to their first post-injury job, with a range of 3 months to 20 years. Fifty percent of the participants who eventually returned to work had done so by 4 years. Return to pre-injury employer and employment were associated with early return, whereas having less years in education and being older at the time of injury were associated with longer time to return to work. Rehabilitation team need to consider return to employment as a realistic goal even many years after SCI. Perhaps a focus on returning more people to their pre-injury employer and employment with added focus and input from rehabilitation team for those with lower education status and older age at time of injury might expedite the process of reintegration.

  4. Two-ball Newton's cradle

    NASA Astrophysics Data System (ADS)

    Glendinning, Paul

    2011-12-01

    Newton's cradle for two balls with Hertzian interactions is considered as a hybrid system, and this makes it possible to derive return maps for the motion between collisions in an exact form despite the fact that the three-halves interaction law cannot be solved in closed form. The return maps depend on a constant whose value can only be determined numerically, but solutions can be written down explicitly in terms of this parameter, and we compare this with the results of simulations. The results are in fact independent of the details of the interaction potential.

  5. Return on Investment in Disease Management: A Review

    PubMed Central

    Goetzel, Ron Z.; Ozminkowski, Ronald J.; Villagra, Victor G.; Duffy, Jennifer

    2005-01-01

    The results of 44 studies investigating financial impact and return on investment (ROI) from disease management (DM) programs for asthma, congestive heart failure (CHF), diabetes, depression, and multiple illnesses were examined. A positive ROI was found for programs directed at CHF and multiple disease conditions. Some evidence suggests that diabetes programs may save more than they cost, but additional studies are needed. Results are mixed for asthma management programs. Depression management programs cost more than they save in medical expenses, but may save money when considering productivity outcomes. PMID:17288065

  6. New ventures require accurate risk analyses and adjustments.

    PubMed

    Eastaugh, S R

    2000-01-01

    For new business ventures to succeed, healthcare executives need to conduct robust risk analyses and develop new approaches to balance risk and return. Risk analysis involves examination of objective risks and harder-to-quantify subjective risks. Mathematical principles applied to investment portfolios also can be applied to a portfolio of departments or strategic business units within an organization. The ideal business investment would have a high expected return and a low standard deviation. Nonetheless, both conservative and speculative strategies should be considered in determining an organization's optimal service line and helping the organization manage risk.

  7. Return on investment in disease management: a review.

    PubMed

    Goetzel, Ron Z; Ozminkowski, Ronald J; Villagra, Victor G; Duffy, Jennifer

    2005-01-01

    The results of 44 studies investigating financial impact and return on investment (ROI) from disease management (DM) programs for asthma, congestive heart failure (CHF), diabetes, depression, and multiple illnesses were examined. A positive ROI was found for programs directed at CHF and multiple disease conditions. Some evidence suggests that diabetes programs may save more than they cost, but additional studies are needed. Results are mixed for asthma management programs. Depression management programs cost more than they save in medical expenses, but may save money when considering productivity outcomes.

  8. Distribution Free Approach for Coordination of a Supply Chain with Consumer Return

    NASA Astrophysics Data System (ADS)

    Hu, Jinsong; Xu, Yuanji

    Consumer return is considered in a coordination of a supply chain consisting of one manufacturer and one retailer. A distribution free approach is employed to deal with a centralized decision model and a decentralized model which are constructed under the situation with only knowing the demand function's mean and variance, respectively. A markdown money contract is designed to coordinate the supply chain, and it is also proved that the contract can make the supply chain perfectly coordinated. Several numerical examples are given at the end of this paper.

  9. Zika virus infections in three travellers returning from South America and the Caribbean respectively, to Montpellier, France, December 2015 to January 2016.

    PubMed

    Maria, Alexandre Thibault; Maquart, Marianne; Makinson, Alain; Flusin, Olivier; Segondy, Michel; Leparc-Goffart, Isabelle; Le Moing, Vincent; Foulongne, Vincent

    2016-01-01

    We report three unrelated cases of Zika virus infection in patients returning from Martinique, Brazil and Colombia respectively, to Montpellier, France. They developed symptoms compatible with a mosquito-borne disease, and serological and molecular investigations indicated a recent Zika virus infection. Considering the recent warning for the likely teratogenicity of Zika virus and the presence of competent mosquito vectors in southern France, these cases highlight the need for awareness of physicians and laboratories in Europe.

  10. "International Migration and Gender Discrimination among Children Left Behind"

    PubMed

    Antman, Francisca M

    2011-05-01

    This paper considers how international migration of the head of household affects the allocation of resources toward boys relative to girls within households remaining in the home country. I address the endogeneity of migration with a differences-in-differences style regression model that compares those households in which migrants have already returned home with those in which migrants are still away. The evidence suggests that while the head of household is away a greater fraction of resources are spent on girls relative to boys, but upon his return, this pattern is reversed.

  11. Cognitive work hardening: a return-to-work intervention for people with depression.

    PubMed

    Wisenthal, Adeena; Krupa, Terry

    2013-01-01

    Mental health claims in the workplace are rising, particularly those due to depression. Associated with this is an increase in disability costs for the employer and the disability insurer, but even more important is the human suffering that results. While treatments are available for the depression there is a gap in interventions that specifically target return-to-work preparation. This paper presents cognitive work hardening, a treatment intervention that can bridge this gap by addressing the unique functional issues inherent in depression with a view to increasing return-to-work success. Cognitive work hardening applies the proven principles of classical work hardening (which has typically been applied to people with physical injuries) to the mental health domain. This paper explains how the occupational therapy principle of occupation and the core competency, enablement, are utilized and applied in cognitive work hardening. Key skills of the occupational therapist are also discussed. In addition, the paper considers the relationship of cognitive work hardening to recovery and mental illness, and the role it plays among workplace-based return-to-work interventions in the current movement toward non-clinical return-to-work interventions.

  12. Exobiology and Future Mars Missions

    NASA Technical Reports Server (NTRS)

    Mckay, Christopher P. (Editor); Davis, Wanda, L. (Editor)

    1989-01-01

    Scientific questions associated with exobiology on Mars were considered and how these questions should be addressed on future Mars missions was determined. The mission that provided a focus for discussions was the Mars Rover/Sample Return Mission.

  13. Streaming PCA with many missing entries.

    DOT National Transportation Integrated Search

    2015-12-01

    This paper considers the problem of matrix completion when some number of the columns are : completely and arbitrarily corrupted, potentially by a malicious adversary. It is well-known that standard : algorithms for matrix completion can return arbit...

  14. 24 CFR 880.608 - Security deposits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... security deposits. (c) In order to be considered for the return of the security deposit, a family which vacates its unit will provide the owner with its forwarding address or arrange to pick up the refund. (d...

  15. 24 CFR 880.608 - Security deposits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... security deposits. (c) In order to be considered for the return of the security deposit, a family which vacates its unit will provide the owner with its forwarding address or arrange to pick up the refund. (d...

  16. 38 CFR 21.6054 - Criteria for determining good employment potential.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... employment prior to the onset of disability. (2) Strong motivation to return to the work force. (3... disagreement with a negative finding shall be considered evidence of motivation for employment, and may, when...

  17. 38 CFR 21.6054 - Criteria for determining good employment potential.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... employment prior to the onset of disability. (2) Strong motivation to return to the work force. (3... disagreement with a negative finding shall be considered evidence of motivation for employment, and may, when...

  18. 38 CFR 21.6054 - Criteria for determining good employment potential.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... employment prior to the onset of disability. (2) Strong motivation to return to the work force. (3... disagreement with a negative finding shall be considered evidence of motivation for employment, and may, when...

  19. 38 CFR 21.6054 - Criteria for determining good employment potential.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... employment prior to the onset of disability. (2) Strong motivation to return to the work force. (3... disagreement with a negative finding shall be considered evidence of motivation for employment, and may, when...

  20. Return to work in sick-listed cancer survivors with job loss: design of a randomised controlled trial.

    PubMed

    van Egmond, Martine P; Duijts, Saskia F A; Vermeulen, Sylvia J; van der Beek, Allard J; Anema, Johannes R

    2015-02-18

    Despite long-term or permanent health problems, cancer survivors are often motivated to return to work. For cancer survivors who have lost their job, return to work can be more challenging compared to employed survivors, as they generally find themselves in a more vulnerable social and financial position. Cancer survivors with job loss may therefore be in need of tailored return to work support. However, there is a lack of return to work intervention programs specifically targeting these cancer survivors. The number of cancer survivors with job loss in developed countries is rising due to, amongst others, increases in the incidence and survivor rate of cancer, the retirement age and the proportion of flexible employment contracts. Hence, we consider it important to develop a tailored return to work intervention program for cancer survivors with job loss, and to evaluate its effectiveness compared to usual care. This study employs a two-armed randomised controlled trial with a follow-up period of 12 months. The study population (n = 164) will be recruited from a national sample of cancer survivors (18-60 years), who have been sick-listed for 12-36 months. Participants will be randomised by using computerized blocked randomisation (blocks of four). All participants will receive usual care as provided by the Dutch Social Security Agency. Additionally, participants in the intervention group will receive a tailored return to work intervention program, which includes vocational rehabilitation and supportive psychosocial components, as well as (therapeutic) placement at work. The primary outcome measure is duration until sustainable return to work; the secondary outcome measure is rate of return to work. Other parameters include, amongst others, fatigue, coping strategy and quality of life. We will perform Cox regression analyses to estimate hazard ratios for time to sustainable return to work. The hypothesis of this study is that a tailored approach for cancer survivors with job loss is more effective, regarding return to work, compared to usual care. The results of this study will provide insight into the ways in which return to work can be facilitated for cancer survivors with job loss. Netherlands Trial Register: NTR3562 .

  1. Fired glaciofluvial sediment in the northwestern Andes: Biotic aspects of the Black Mat

    NASA Astrophysics Data System (ADS)

    Mahaney, William C.; Krinsley, David; Langworthy, Kurt; Kalm, Volli; Havics, Tony; Hart, Kris M.; Kelleher, Brian P.; Schwartz, Stephane; Tricart, Pierre; Beukens, Roelf

    2011-05-01

    Fired glaciofluvial beds in outwash considered to date from the onset of the Younger Dryas Event (~ 12.9 ka) in the northwestern Venezuelan Andes are considered equivalent to the Black Mat deposits described in other areas of North and South America and Europe. It may be equivalent to sediment recovered from other sites containing beds with spikes of cosmic nuclides and charcoal indicating the presence of widespread fire, one of the signatures of the Black Mat conflagration that followed the proposed breakup of Comet Encke or an unknown asteroid over the Laurentide Icesheet at 12.9 ka. In the northern Andes at Site MUM7B, sediment considered coeval with the Black Mat contains glassy carbon spherules, tri-coatings of C welded onto quartz and feldspar covered with Fe and Mn. Monazite with excessive concentrations of REEs, platinum metals including Ru and Rh, possible pdf's, and disrupted/brecciated and microfractured quartz and feldspar from impacting ejecta and excessive heating summarize the data obtained so far. The purpose of this paper is to document the physical character, mineralogy and biotic composition of the Black Mat.

  2. Probability modeling of high flow extremes in Yingluoxia watershed, the upper reaches of Heihe River basin

    NASA Astrophysics Data System (ADS)

    Li, Zhanling; Li, Zhanjie; Li, Chengcheng

    2014-05-01

    Probability modeling of hydrological extremes is one of the major research areas in hydrological science. Most basins in humid and semi-humid south and east of China are concerned for probability modeling analysis of high flow extremes. While, for the inland river basin which occupies about 35% of the country area, there is a limited presence of such studies partly due to the limited data availability and a relatively low mean annual flow. The objective of this study is to carry out probability modeling of high flow extremes in the upper reach of Heihe River basin, the second largest inland river basin in China, by using the peak over threshold (POT) method and Generalized Pareto Distribution (GPD), in which the selection of threshold and inherent assumptions for POT series are elaborated in details. For comparison, other widely used probability distributions including generalized extreme value (GEV), Lognormal, Log-logistic and Gamma are employed as well. Maximum likelihood estimate is used for parameter estimations. Daily flow data at Yingluoxia station from 1978 to 2008 are used. Results show that, synthesizing the approaches of mean excess plot, stability features of model parameters, return level plot and the inherent independence assumption of POT series, an optimum threshold of 340m3/s is finally determined for high flow extremes in Yingluoxia watershed. The resulting POT series is proved to be stationary and independent based on Mann-Kendall test, Pettitt test and autocorrelation test. In terms of Kolmogorov-Smirnov test, Anderson-Darling test and several graphical diagnostics such as quantile and cumulative density function plots, GPD provides the best fit to high flow extremes in the study area. The estimated high flows for long return periods demonstrate that, as the return period increasing, the return level estimates are probably more uncertain. The frequency of high flow extremes exhibits a very slight but not significant decreasing trend from 1978 to 2008, while the intensity of such flow extremes is comparatively increasing especially for the higher return levels.

  3. Radioactivites in returned lunar materials and in meteorites

    NASA Technical Reports Server (NTRS)

    Fireman, E. L.

    1983-01-01

    The cosmic-ray, solar-flare, and solar-wind bombardments of lunar rocks and soils and meteorites were studied by measurements of tritium, carbon-14 and argon radioactivity. The radioactivity integrates the bombardment for a time period equal to several half-lines. H-3, Ar-37, Ar-39, C-14. For the interior samples of lunar rocks and for deep lunar soil samples, the amounts of the radioactivities were equal to those calculated for galactic cosmic-ray interactions. The top near-surface samples of lunar rocks and the shallow lunar soil samples show excess amounts of the radioactivities attributable to solar flares. Lunar soil fines contain a large amount of hydrogen due to implanted solar wind. Studies of the H-3 in lunar soils and in recovered Surveyor-3 materials gave an upper limit for the H-3/H ratio in the solar wind of 10 to the -11th power. Solar wind carbon is also implanted on lunar soil fines. Lunar soils collected on the surface contained a 0.14 component attributable to implanted solar wind C-14. The C-14/H ratio attributed to the solar wind from this C-14 excess is approximately 4 x 10 to the -11th power.

  4. Defining the mechanical properties of a spring-hinged ankle foot orthosis to assess its potential use in children with spastic cerebral palsy.

    PubMed

    Kerkum, Yvette L; Brehm, Merel-Anne; Buizer, Annemieke I; van den Noort, Josien C; Becher, Jules G; Harlaar, Jaap

    2014-12-01

    A rigid ventral shelf ankle foot orthosis (AFO) may improve gait in children with spastic cerebral palsy (SCP) whose gait is characterized by excessive knee flexion in stance. However, these AFOs can also impede ankle range of motion (ROM) and thereby inhibit push-off power. A more spring-like AFO can enhance push-off and may potentially reduce walking energy cost. The recent development of an adjustable spring-hinged AFO now allows adjustment of AFO stiffness, enabling tuning toward optimal gait performance. This study aims to quantify the mechanical properties of this spring-hinged AFO for each of its springs and settings. Using an AFO stiffness tester, two AFO hinges and their accompanying springs were measured. The springs showed a stiffness range of 0.01-1.82 N · m · deg(-1). The moment-threshold increased with increasing stiffness (1.13-12.1 N · m), while ROM decreased (4.91-16.5°). Energy was returned by all springs (11.5-116.3 J). These results suggest that the two stiffest available springs should improve joint kinematics and enhance push-off in children with SCP walking with excessive knee flexion.

  5. Effects of chemical sludge disintegration on the performances of wastewater treatment by membrane bioreactor.

    PubMed

    Oh, Young-Khee; Lee, Ki-Ryong; Ko, Kwang-Baik; Yeom, Ick-Tae

    2007-06-01

    A new wastewater treatment process combining a membrane bioreactor (MBR) with chemical sludge disintegration was tested in bench scale experiments. In particular, the effects of the disintegration treatment on the excess sludge production in MBR were investigated. Two MBRs were operated. In one reactor, a part of the mixed liquor was treated with NaOH and ozone gas consecutively and was returned to the bioreactor. The flow rate of the sludge disintegration stream was 1.5% of the influent flow rate. During the 200 days of operation, the MLSS level in the bioreactor with the disintegration treatment was maintained relatively constant at the range of 10,000-11,000 mg/L while it increased steadily up to 25,000 mg/L in the absence of the treatment. In the MBR with the sludge disintegration, relatively constant transmembrane pressures (TMPs) could be maintained for more than 6 months while the MBR without disintegration showed an abrupt increase of TMP in the later phase of the operation. In conclusion, a complete control of excess sludge production in the membrane-coupled bioreactor was possible without significant deterioration of the treated water quality and membrane performances.

  6. Space Radiation Cancer Risk Projections for Exploration Missions: Uncertainty Reduction and Mitigation

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis; Badhwar, Gautam; Saganti, Premkumar; Schimmerling, Walter; Wilson, John; Peterson, Leif; Dicello, John

    2002-01-01

    In this paper we discuss expected lifetime excess cancer risks for astronauts returning from exploration class missions. For the first time we make a quantitative assessment of uncertainties in cancer risk projections for space radiation exposures. Late effects from the high charge and energy (HZE) ions present in the galactic cosmic rays including cancer and the poorly understood risks to the central nervous system constitute the major risks. Methods used to project risk in low Earth orbit are seen as highly uncertain for projecting risks on exploration missions because of the limited radiobiology data available for estimating HZE ion risks. Cancer risk projections are described as a product of many biological and physical factors, each of which has a differential range of uncertainty due to lack of data and knowledge. Monte-Carlo sampling from subjective error distributions represents the lack of knowledge in each factor to quantify risk projection overall uncertainty. Cancer risk analysis is applied to several exploration mission scenarios. At solar minimum, the number of days in space where career risk of less than the limiting 3% excess cancer mortality can be assured at a 95% confidence level is found to be only of the order of 100 days.

  7. Permanent Magnet Synchronous Motor Driven by PWM Inverter with Voltage Booster with Regenerating Capability Augmented by Double-Layer Capacitor

    NASA Astrophysics Data System (ADS)

    Yamamoto, Kichiro; Shinohara, Katsuji; Furukawa, Shinya

    An interior permanent magnet (IPM) motor drive system which has regenerating capability augmented by double-layer capacitors is proposed. The motor is driven by a PWM inverter with voltage booster. The voltage booster is used to control the dc link voltage in high speed region to improve the system efficiency. Furthermore, the double-layer capacitor as a storage element is combined with the PWM inverter with voltage booster to gain the efficiency for the regenerating operation. In this system, normally, the regenerative power does not return to a battery directly but is stored in the double-layer capacitors for the next motoring action to suppress the excessive regenerative current to battery, and the regenerative power returns to the battery when the regenerative energy is larger than a certain value. The charging current to the battery is controlled to a constant value to extend the life-time of the battery. The transient and steady state characteristics of the system for 1.5kW IPM motor are investigated by both simulation and experiment. Finally, the effectiveness of the system is demonstrated by the simulated and experimental results.

  8. Return period curves for extreme 5-min rainfall amounts at the Barcelona urban network

    NASA Astrophysics Data System (ADS)

    Lana, X.; Casas-Castillo, M. C.; Serra, C.; Rodríguez-Solà, R.; Redaño, A.; Burgueño, A.; Martínez, M. D.

    2018-03-01

    Heavy rainfall episodes are relatively common in the conurbation of Barcelona and neighbouring cities (NE Spain), usually due to storms generated by convective phenomena in summer and eastern and south-eastern advections in autumn. Prevention of local flood episodes and right design of urban drainage have to take into account the rainfall intensity spread instead of a simple evaluation of daily rainfall amounts. The database comes from 5-min rain amounts recorded by tipping buckets in the Barcelona urban network along the years 1994-2009. From these data, extreme 5-min rain amounts are selected applying the peaks-over-threshold method for thresholds derived from both 95% percentile and the mean excess plot. The return period curves are derived from their statistical distribution for every gauge, describing with detail expected extreme 5-min rain amounts across the urban network. These curves are compared with those derived from annual extreme time series. In this way, areas in Barcelona submitted to different levels of flood risk from the point of view of rainfall intensity are detected. Additionally, global time trends on extreme 5-min rain amounts are quantified for the whole network and found as not statistically significant.

  9. Fate of return activated sludge after ozonation: an optimization study for sludge disintegration.

    PubMed

    Demir, Ozlem; Filibeli, Ayse

    2012-09-01

    The effects of ozonation on sludge disintegration should be investigated before the application of ozone during biological treatment, in order to minimize excess sludge production. In this study, changes in sludge and supernatant after ozonation of return activated sludge were investigated for seven different ozone doses. The optimum ozone dose to avoid inhibition of ozonation and high ozone cost was determined in terms of disintegration degree as 0.05 g O3/gTS. Suspended solid and volatile suspended solid concentrations of sludge decreased by 77.8% and 71.6%, respectively, at the optimum ozone dose. Ozonation significantly decomposed sludge flocs. The release of cell contents was proved by the increase of supernatant total nitrogen (TN) and phosphorus (TP). While TN increased from 7 mg/L to 151 mg/L, TP increased from 8.8 to 33 mg/L at the optimum ozone dose. The dewaterability and filterability characteristics of the ozonated sludge were also examined. Capillary suction time increased with increasing ozone dosage, but specific resistance to filtration increased to a specific value and then decreased dramatically. The particle size distribution changed significantly as a result of floc disruption at an optimum dose of 0.05 gO3/gTS.

  10. Experiment K305: Quantitative analysis of selected bone parameters. Supplement 2: Bone elongation rate and bone mass in metaphysis of long bones

    NASA Technical Reports Server (NTRS)

    Jee, W. S. S.; Kimmel, D. B.; Smith, C.; Dell, R. B.

    1981-01-01

    The proximal humeral metaphysis of rats from time periods recovery plus zero days (R+0), recovery plus six days (R+6), and recovery plus twenty nine days (R+29) was analyzed. The volume of calcified cartilage and bone in flight and synchronous controls was reduced in groups R+0 and R+6, but was normal in group R+29. The number of functional bone cells (osteoblasts and osteoclasts) was decreased in proportion to the amount of bone in the early groups, and was normal in the last group. The fatty marrow volume was increased only in flight animals of groups R+0 and R+6, but was normal in the R+29 group. Accumulation of excess fatty marrow was seen only in flight animals. The decreased amount of bone and calcified cartilage is believed to be the result of a temporarily slowed or arrested production of calcified cartilage as a substrate for bone formation. This would have resulted from slowed bone elongation during flight and synchronous control conditions. Bone elongation returned to normal by twenty nine days after return.

  11. Is ice right? Does cryotherapy improve outcome for acute soft tissue injury?

    PubMed

    Collins, N C

    2008-02-01

    The use of ice or cryotherapy in the management of acute soft tissue injuries is widely accepted and widely practised. This review was conducted to examine the medical literature to investigate if there is evidence to support an improvement in clinical outcome following the use of ice or cryotherapy. A comprehensive literature search was performed and all human and animal trials or systematic reviews pertaining to soft tissue trauma, ice or cryotherapy were assessed. The clinically relevant outcome measures were (1) a reduction in pain; (2) a reduction in swelling or oedema; (3) improved function; or (4) return to participation in normal activity. Six relevant trials in humans were identified, four of which lacked randomisation and blinding. There were two well conducted randomised controlled trials, one showing supportive evidence for the use of a cooling gel and the other not reaching statistical significance. Four animal studies showed that modest cooling reduced oedema but excessive or prolonged cooling is damaging. There were two systematic reviews, one of which was inconclusive and the other suggested that ice may hasten return to participation. There is insufficient evidence to suggest that cryotherapy improves clinical outcome in the management of soft tissue injuries.

  12. A nonmedical approach to fertility reduction. An experimental contraceptive service unit.

    PubMed

    Gobble, F L; Vincent, C E; Cochrane, C M; Lock, F R

    1969-12-01

    A preliminary report if given of results of 3 walk-up Contraceptive Service (CS) Units started in Forsyth County, North Carolina, by the Behavioral Science Center of Bowman Gray School of Medicine that tried through an experimental and nonmedical approach to reduce fertility among young poverty-level females by focusing on young sexually active males. 552 new and 874 returning clients visited the CS units during the first 7 months of the experiment. 90% new and 98% returning clients have been male. The first clinic was opened September 1, 1968, 3 hours each evening except Sunday. In November a second clinic was opened in March. Each was staffed by a nonmedical trained counselor. A choice of condoms, foam, or jelly and instruction in proper technics in using these methods provided at no cost. Male clients have been highly responsive, entering freely into discussion. Objections to mechanical methods were removed by instruction in proper use. Most requested condoms and foam. Location accounts different degrees of success and will be evaluated in a future report. CS effectiveness should be measured in lower venereal disease incidence. Further evaluation will include excess fertility analysis and numerator anaylsis.

  13. Calculating excess lifetime risk in relative risk models.

    PubMed Central

    Vaeth, M; Pierce, D A

    1990-01-01

    When assessing the impact of radiation exposure it is common practice to present the final conclusions in terms of excess lifetime cancer risk in a population exposed to a given dose. The present investigation is mainly a methodological study focusing on some of the major issues and uncertainties involved in calculating such excess lifetime risks and related risk projection methods. The age-constant relative risk model used in the recent analyses of the cancer mortality that was observed in the follow-up of the cohort of A-bomb survivors in Hiroshima and Nagasaki is used to describe the effect of the exposure on the cancer mortality. In this type of model the excess relative risk is constant in age-at-risk, but depends on the age-at-exposure. Calculation of excess lifetime risks usually requires rather complicated life-table computations. In this paper we propose a simple approximation to the excess lifetime risk; the validity of the approximation for low levels of exposure is justified empirically as well as theoretically. This approximation provides important guidance in understanding the influence of the various factors involved in risk projections. Among the further topics considered are the influence of a latent period, the additional problems involved in calculations of site-specific excess lifetime cancer risks, the consequences of a leveling off or a plateau in the excess relative risk, and the uncertainties involved in transferring results from one population to another. The main part of this study relates to the situation with a single, instantaneous exposure, but a brief discussion is also given of the problem with a continuous exposure at a low-dose rate. PMID:2269245

  14. Effect of excess iodine intake on thyroid diseases in different populations: A systematic review and meta-analyses including observational studies

    PubMed Central

    Katagiri, Ryoko; Yuan, Xiaoyi; Kobayashi, Satomi; Sasaki, Satoshi

    2017-01-01

    Background Although several reports concerning the association of iodine excess and thyroid disease have appeared, no systematic review of the association between iodine excess intake and thyroid diseases, especially hyperthyroidism and hypothyroidism, has yet been reported. Method We conducted a systematic search of Ovid MEDLINE, PubMed, Cochrane Central Register of Controlled Trials databases, Ichushi-Web and CiNii database for intervention trials and observational studies. Search terms were constructed from related words for excess AND iodine intake or excretion AND thyroid hormones or diseases AND study designs. After considering the qualitative heterogeneity among studies, a meta-analysis was conducted and odds ratios and 95% confidence intervals (CI) were estimated in random-effects models. A protocol was registered with PROSPERO (No. CRD42015028081). Results 50 articles were included, including three intervention trials, six case-control studies, six follow-up studies and 35 cross-sectional studies. Three cross-sectional studies in adults included in meta-analysis. Odds ratio of overt and subclinical hypothyroidism between excess and adequate populations were 2.78 (CI:1.47 to 5.27) and 2.03 (CI:1.58 to 2.62) in adults, respectively. Source of excess iodine status was mainly iodized salt or water in included studies. Conclusion Although universal salt iodization has improved goiter rates, chronic exposure to excess iodine from water or poorly monitored salt are risk factors for hypothyroidism in free-living populations. Monitoring of both iodine concentration in salt as well as the iodine concentration in local drinking water are essential to preventing thyroid diseases. Hypothyroidism should be also carefully monitored in areas with excess iodine. Because of the low quality and limited number of included studies, further evidence and review are required. PMID:28282437

  15. Calculating excess lifetime risk in relative risk models.

    PubMed

    Vaeth, M; Pierce, D A

    1990-07-01

    When assessing the impact of radiation exposure it is common practice to present the final conclusions in terms of excess lifetime cancer risk in a population exposed to a given dose. The present investigation is mainly a methodological study focusing on some of the major issues and uncertainties involved in calculating such excess lifetime risks and related risk projection methods. The age-constant relative risk model used in the recent analyses of the cancer mortality that was observed in the follow-up of the cohort of A-bomb survivors in Hiroshima and Nagasaki is used to describe the effect of the exposure on the cancer mortality. In this type of model the excess relative risk is constant in age-at-risk, but depends on the age-at-exposure. Calculation of excess lifetime risks usually requires rather complicated life-table computations. In this paper we propose a simple approximation to the excess lifetime risk; the validity of the approximation for low levels of exposure is justified empirically as well as theoretically. This approximation provides important guidance in understanding the influence of the various factors involved in risk projections. Among the further topics considered are the influence of a latent period, the additional problems involved in calculations of site-specific excess lifetime cancer risks, the consequences of a leveling off or a plateau in the excess relative risk, and the uncertainties involved in transferring results from one population to another. The main part of this study relates to the situation with a single, instantaneous exposure, but a brief discussion is also given of the problem with a continuous exposure at a low-dose rate.

  16. What Are the Symptoms of Polycystic Ovary Syndrome (PCOS)?

    MedlinePlus

    ... but no ovulation—called anovulatory periods Infertility Excess hair growth on the face, chest, belly, or upper thighs— ... t consider problems such as oily skin, extra hair growth, or acne to be symptoms of a serious ...

  17. 28 CFR 549.61 - Definition.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) When he or she communicates that fact to staff and is observed by staff to be refraining from eating... refraining from eating for a period in excess of 72 hours. When staff consider it prudent to do so, a...

  18. Radiation Risk From Medical Imaging

    PubMed Central

    Lin, Eugene C.

    2010-01-01

    This review provides a practical overview of the excess cancer risks related to radiation from medical imaging. Primary care physicians should have a basic understanding of these risks. Because of recent attention to this issue, patients are more likely to express concerns over radiation risk. In addition, physicians can play a role in reducing radiation risk to their patients by considering these risks when making imaging referrals. This review provides a brief overview of the evidence pertaining to low-level radiation and excess cancer risks and addresses the radiation doses and risks from common medical imaging studies. Specific subsets of patients may be at greater risk from radiation exposure, and radiation risk should be considered carefully in these patients. Recent technical innovations have contributed to lowering the radiation dose from computed tomography, and the referring physician should be aware of these innovations in making imaging referrals. PMID:21123642

  19. An Economic Analysis of Residential Photovoltaic Systems with and without Energy Storage

    NASA Astrophysics Data System (ADS)

    Kizito, Rodney

    Residential photovoltaic (PV) systems serve as a source of electricity generation that is separate from the traditional utilities. Investor investment into residential PV systems provides several financial benefits such as federal tax credit incentives for installation, net metering credit from excess generated electricity added back to the grid, and savings in price per kilowatt-hour (kWh) from the PV system generation versus the increasing conventional utility price per kWh. As much benefit as stand-alone PV systems present, the incorporation of energy storage yields even greater benefits. Energy storage (ES) is capable of storing unused PV provided energy from daytime periods of high solar supply but low consumption. This allows the investor to use the stored energy when the cost of conventional utility power is high, while also allowing for excess stored energy to be sold back to the grid. This paper aims to investigate the overall returns for investor's investing in solely PV and ES-based PV systems by using a return of investment (ROI) economic analysis. The analysis is carried out over three scenarios: (1) residence without a PV system or ES, (2) residence with just a PV system, and (3) residence with both a PV system and ES. Due to the variation in solar exposure across the regions of the United States, this paper performs an analysis for eight of the top solar market states separately, accounting for the specific solar generation capabilities of each state. A Microsoft Excel tool is provided for computation of the ROI in scenario 2 and 3. A benefit-cost ration (BCR) is used to depict the annual economic performance of the PV system (scenario 2) and PV + ES system (scenario 3). The tool allows the user to adjust the variables and parameters to satisfy the users' specific investment situation.

  20. Prioritizing Site-Selection And Use

    EPA Science Inventory

    Land subject to remediation is usually considered relative to its availability and its potential financial return-on-investment. Typically, these short-term considerations are unrelated to the long-term conditional relationships that exist between humanity and a sustainable envi...

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