Cyber Intelligence Research Consortium (Poster)

DTIC Science & Technology

2014-10-24

OCT 2014 2. REPORT TYPE N/A 3. DATES COVERED 4. TITLE AND SUBTITLE Cyber Intelligence Research Consortium Poster 5a. CONTRACT NUMBER 5b...nontechnical audiences Environmental Context Provides scope for the analytical effort • Highlights the importance of context - technical and nontechnical... Environmental Context Reporting & Feedback Macroanalysis Microanalysis Data Gathering Steering Committee: Guide Consortium activities and plan for future

25 CFR 1000.68 - May non-BIA bureaus provide technical assistance to a Tribe/Consortium in drafting its planning...

Code of Federal Regulations, 2010 CFR

2010-04-01

... Financial Assistance for Planning and Negotiation Grants for Non-BIA Programs Eligibility and Application... Tribe/Consortium in drafting its planning grant application? 1000.68 Section 1000.68 Indians OFFICE OF... planning grant application? Yes, upon request from the Tribe/Consortium, a non-BIA bureau may provide...

Northeast Artificial Intelligence Consortium Annual Report - 1988 Parallel Vision. Volume 9

DTIC Science & Technology

1989-10-01

supports the Northeast Aritificial Intelligence Consortium (NAIC). Volume 9 Parallel Vision Report submitted by Christopher M. Brown Randal C. Nelson...NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM ANNUAL REPORT - 1988 Parallel Vision Syracuse University Christopher M. Brown and Randal C. Nelson...Technical Director Directorate of Intelligence & Reconnaissance FOR THE COMMANDER: IGOR G. PLONISCH Directorate of Plans & Programs If your address has

Biomass power for rural development: Phase 2. Technical progress report, April 1--June 30, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuhauser, E.

1998-11-01

The project undertaken by the Salix Consortium is a multi-phased, multi-partner endeavor. Phase-1 focused on initial development and testing of the technology and agreements necessary to demonstrate commercial willow production in Phase-2. The Phase-1 objectives have been successfully completed: preparing final design plans for two utility pulverized coal boilers, developing fuel supply plans for the project, obtaining power production commitments from the power companies for Phase-2, obtaining construction and environmental permits, and developing an experimental strategy for crop production and power generation improvements needed to assure commercial success. The R and D effort also addresses environmental issues pertaining to introductionmore » of the willow energy system. Beyond those Phase-1 requirements the Consortium has already successfully demonstrated cofiring at Greenidge Station and developed the required nursery capacity for acreage scale-up. This past summer 105 acres were prepared in advance for the spring planting in 1998. Having completed the above tasks, the Consortium is well positioned to begin Phase-2. In phase-2 every aspect of willow production and power generation from willow will be demonstrated. The ultimate objective of Phase-2 is to transition the work performed under the Rural Energy for the Future project into a thriving, self-supported energy crop enterprise.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, David E.

The JEMA modulator was originally developed for the European Spallation Source (ESS) when Spain was under consideration as a location for the ESS facility. Discussions ensued and the Spallation Neutron Source Research Accelerator Division agreed to form a collaboration with ESS-Bilbao (ESS-B) consortium to provide services for specifying the requirements for a version of the modulator capable of operating twelve 550 kW klystrons, monitoring the technical progress on the contract with JEMA, installing and commissioning the modulator at SNS, and performing a 30 day full power test. This work was recently completed, and this report discusses those activities with primarymore » emphasis on the installation and testing activities.« less

Silicon Anode Consortium | Transportation Research | NREL

Science.gov Websites

Stabilization, Second Quarter Progress Report 2018 Next Generation Anodes for Lithium-Ion Batteries, Second 2018 Next Generation Anodes for Lithium-Ion Batteries, First Quarter Progress Report 2018 Contact For consortium focuses on understanding and eliminating barriers to implementing silicon-based anodes in Li-ion

78 FR 47674 - Genome in a Bottle Consortium-Progress and Planning Workshop

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-06

... quantitative performance metrics for confidence in variant calling. These standards and quantitative..., reproducible research and regulated applications in the clinic. On April 13, 2012, NIST convened the workshop... consortium. No proprietary information will be shared as part of the consortium, and all research results...

The 1980 V-TECS Marketing Study.

ERIC Educational Resources Information Center

Hattwick, Richard E.; And Others

The Vocational-Technical Education Consortium of States (V-TECS) conducted a marketing study that considered the implications of six options for the organization's future. The first option is continuation of the status quo, which is dangerous because existing members may leave the consortium. The second option is the status quo combined with an…

GridAPPS-D Conceptual Design v1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Melton, Ronald B.; Schneider, Kevin P.; McDermott, Thomas E.

2017-05-31

The purpose of this document is to provide a conceptual design of the distribution system application development platform being developed for the U.S. Department of Energy’s Advanced Distribution Management System (ADMS) Program by the Grid Modernization Laboratory Consortium project GM0063. The platform will be referred to as GridAPPS-D. This document provides a high level, conceptual view of the platform and provides related background and contextual information. This document is intended to both educate readers about the technical work of the project and to serve as a point of reference for the project team. The document will be updated as themore » project progresses.« less

Surface Dielectric Barrier Discharge Jet for Skin Disinfection

NASA Astrophysics Data System (ADS)

Creyghton, Yves; Meijer, Rogier; Verweij, Paul; van der Zanden, Frank; Leenders, Paul

A consortium consisting of the research institute TNO, the medical ­university and hospital St Radboud and two industrial enterprises is working on a non-thermal plasma treatment method for hand disinfection. The group is seeking for cooperation, in particular in the field of validation methods and potential ­standardization for plasma based disinfection procedures. The present paper describes technical progress in plasma source development together with initial microbiological data. Particular properties of the sheet shaped plasma volume are the possibility of treating large irregular surfaces in a short period of time, effective plasma produced species transfer to the surface together with high controllability of the nature of plasma species by means of temperature conditioning.

Consortium for military LCD display procurement

NASA Astrophysics Data System (ADS)

Echols, Gregg

2002-08-01

International Display Consortium (IDC) is the joining together of display companies to combined their buying power and obtained favorable terms with a major LCD manufacturer. Consolidating the buying power and grouping the demand enables the rugged display industry of avionics, ground vehicles, and ship based display manufacturers to have unencumbered access to high performance AMLCDs while greatly reducing risk and lowering cost. With an unrestricted supply of AMLCD displays, the consortium members have total control of their risk, cost, deliveries and added value partners. Every display manufacturer desires a very close relationship with a display vender. With IDC each consortium member achieves a close relationship. Consortium members enjoy cost effective access to high performance, industry standard sized LCD panels, and modified commercial displays with 100 degree C clearing points and portrait configurations. Consortium members also enjoy proposal support, technical support and long-term support.

Preparing Workforce 2000 through Vocational Technical 2+2 Programs.

ERIC Educational Resources Information Center

Portland Area Vocational-Technical Education Consortium, OR.

An overview is provided of the 1989 accomplishments of the Portland Area Vocational Technical Education Consortium (PAVTEC), which was created to strengthen partnerships between Portland Community College (PCC) and local high schools to provide high quality articulated vocational-technical programs. The first section looks at the roles of PAVTEC,…

V-TECS Career Cluster Frameworks.

ERIC Educational Resources Information Center

Vocational Technical Education Consortium of States, Decatur, GA.

This document includes 16 vocational-technical crosswalk wheels relating the 14 Vocational Technical Education Consortium of States (V-TECS) Career Families to the 16 Career Clusters developed by the U.S. Department of Education. The career clusters are based on the common academic, workplace, and technical knowledge and skills that cut across all…

Overview of the World Wide Web Consortium (W3C) (SIGs IA, USE).

ERIC Educational Resources Information Center

Daly, Janet

2000-01-01

Provides an overview of a planned session to describe the work of the World Wide Web Consortium, including technical specifications for HTML (Hypertext Markup Language), XML (Extensible Markup Language), CSS (Cascading Style Sheets), and over 20 other Web standards that address graphics, multimedia, privacy, metadata, and other technologies. (LRW)

National Centers for Career and Technical Education Annual Report, 2000.

ERIC Educational Resources Information Center

National Dissemination Center for Career and Technical Education, Columbus, OH.

The National Research Center for Career and Technical Education and the National Dissemination Center for Career and Technical Education were established at the University of Minnesota and The Ohio State University, respectively, in 1999. The centers operate as a consortium with primary and associate partners. Through the centers, the partners…

Connections for the Future through Vocational Technical 2 + 2 Programs. Annual Report, April 1989.

ERIC Educational Resources Information Center

Portland Area Vocational-Technical Education Consortium, OR.

The Portland Area Vocational Technical Education Consortium (PAVTEC) was created to enhance and strengthen the working partnerships between Portland Community College and local high schools in order to provide high quality, articulated vocational technical programs. PAVTEC's third annual report highlights activities which have added to the…

Biomass power for rural development. Technical progress report, July 1--September 30, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuhauser, E.

The focus of the DOE/USDA sponsored biomass power for rural development project is to develop commercial energy crops for power generation by the year 2000. The New York based Salix Consortium project is a multi-partner endeavor, implemented in three stages. Phase-1, Final Design and Project Development, will conclude with the preparation of construction and/or operating permits, feedstock production plans, and contracts ready for signature. Field trials of willow (Salix) have been initiated at several locations in New York (Tully, Lockport, King Ferry, La Fayette, Massena, and Himrod) and co-firing tests are underway at Greenidge Station (NYSEG) and Dunkirk Station (NMPC).more » Phase-2 of the project will focus on scale-up of willow crop acreage, construction of co-firing facilities at Dunkirk Station (NMPC), and final modifications for Greenidge Station. Cofiring willow is also under consideration for GPU`s Seward Station where testing is underway. There will be an evaluation of the energy crop as part of the gasification trials occurring at BED`s McNeill power station. Phase-3 will represent fullscale commercialization of the energy crop and power generation on a sustainable basis. During the third quarter of 1997, much of the Consortium`s effort has focused on outreach activities, continued feedstock development, fuel supply planning, and fuel contract development, and preparation for 1998 scale-up activities. The Consortium also submitted a Phase-1 extension proposal during this period. A few of the more important milestones are outlined below. The fourth quarter of 1997 is expected to be dominated by Phase-II proposal efforts and planning for 1998 activities.« less

Midwest Transportation Consortium annual progress report : October 2000.

DOT National Transportation Integrated Search

2000-10-01

From the Director: The Midwest Transportation Consortium (MTC), the University Transportation Center serving the states : of Iowa, Kansas, Missouri, and Nebraska, had a very successful first year of operation. The MTC is a : complex partnership invol...

Duchenne Regulatory Science Consortium Meeting on Disease Progression Modeling for Duchenne Muscular Dystrophy.

PubMed

Larkindale, Jane; Abresch, Richard; Aviles, Enrique; Bronson, Abby; Chin, Janice; Furlong, Pat; Gordish-Dressman, Heather; Habeeb-Louks, Elizabeth; Henricson, Erik; Kroger, Hans; Lynn, Charles; Lynn, Stephen; Martin, Dana; Nuckolls, Glen; Rooney, William; Romero, Klaus; Sweeney, Lee; Vandenborne, Krista; Walter, Glenn; Wolff, Jodi; Wong, Brenda; McDonald, Craig M; Duchenne Regulatory Science Consortium Imaging-Dmd Consortium And The Cinrg Investigators, Members Of The

2017-01-12

The Duchenne Regulatory Science Consortium (D-RSC) was established to develop tools to accelerate drug development for DMD.  The resulting tools are anticipated to meet validity requirements outlined by qualification/endorsement pathways at both the U.S. Food and Drug Administration (FDA) and European Medicines Administration (EMA), and will be made available to the drug development community. The initial goals of the consortium include the development of a disease progression model, with the goal of creating a model that would be used to forecast changes in clinically meaningful endpoints, which would inform clinical trial protocol development and data analysis.  Methods: In April of 2016 the consortium and other experts met to formulate plans for the development of the model.  Conclusions: Here we report the results of the meeting, and discussion as to the form of the model that we plan to move forward to develop, after input from the regulatory authorities.

Vehicle infrastructure integration proof of concept : technical description--vehicle : final report

DOT National Transportation Integrated Search

2009-05-19

This report provides the technical description of the VII system developed for the Cooperative Agreement VII Program between the USDOT and the VII Consortium. The basic architectural elements are summarized and detailed descriptions of the hardware a...

Midwest Transportation Consortium annual progress report : October 2002.

DOT National Transportation Integrated Search

2002-10-01

From the Director: For the past three years, the Midwest Transportation Consortium (MTC) has focused its efforts in : supporting the development and use of asset management systems in transportation. The MTCs main : focus is on human capital devel...

Final Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rasure, John, et. al.

Through past DOE funding, the MIND Research network has funded a national consortium effort that used multi-modal neuroimaging, genetics, and clinical assessment of subjects to study schizophrenia in both first episode and persistently ill patients. Although active recruitment of research participants is complete, this consortium remains active and productive in terms of analysis of this unique multi-modal data collected on over 320 subjects.

Midwest Nuclear Science and Engineering Consortium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dr. Wynn Volkert; Dr. Arvind Kumar; Dr. Bryan Becker

2010-12-08

The objective of the Midwest Nuclear Science and Engineering Consortium (MNSEC) is to enhance the scope, quality and integration of educational and research capabilities of nuclear sciences and engineering (NS/E) programs at partner schools in support of the U.S. nuclear industry (including DOE laboratories). With INIE support, MNSEC had a productive seven years and made impressive progress in achieving these goals. Since the past three years have been no-cost-extension periods, limited -- but notable -- progress has been made in FY10. Existing programs continue to be strengthened and broadened at Consortium partner institutions. The enthusiasm generated by the academic, state,more » federal, and industrial communities for the MNSEC activities is reflected in the significant leveraging that has occurred for our programs.« less

The MRI-Linear Accelerator Consortium: Evidence-Based Clinical Introduction of an Innovation in Radiation Oncology Connecting Researchers, Methodology, Data Collection, Quality Assurance, and Technical Development.

PubMed

Kerkmeijer, Linda G W; Fuller, Clifton D; Verkooijen, Helena M; Verheij, Marcel; Choudhury, Ananya; Harrington, Kevin J; Schultz, Chris; Sahgal, Arjun; Frank, Steven J; Goldwein, Joel; Brown, Kevin J; Minsky, Bruce D; van Vulpen, Marco

2016-01-01

An international research consortium has been formed to facilitate evidence-based introduction of MR-guided radiotherapy (MR-linac) and to address how the MR-linac could be used to achieve an optimized radiation treatment approach to improve patients' survival, local, and regional tumor control and quality of life. The present paper describes the organizational structure of the clinical part of the MR-linac consortium. Furthermore, it elucidates why collaboration on this large project is necessary, and how a central data registry program will be implemented.

Northeast Artificial Intelligence Consortium Annual Report 1986. Volume 4. Part A. Hierarchical Region-Based Approach to Automatic Photointerpretation. Part B. Application of AI Techniques to Image Segmentation and Region Identification

DTIC Science & Technology

1988-01-01

MONITORING ORGANIZATION Northeast Artificial (If applicaole)nelincCostum(AcRome Air Development Center (COCU) Inteligence Consortium (NAIC)I 6c. ADDRESS...f, Offell RADC-TR-88-1 1, Vol IV (of eight) Interim Technical ReportS June 1988 NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM ANNUAL REPORT 1986...13441-5700 EMENT NO NO NO ACCESSION NO62702F 5 8 71 " " over) I 58 27 13 " ൓ TITLE (Include Security Classification) NORTHEAST ARTIFICIAL INTELLIGENCE

Duchenne Regulatory Science Consortium Meeting on Disease Progression Modeling for Duchenne Muscular Dystrophy

PubMed Central

Larkindale, Jane; Abresch, Richard; Aviles, Enrique; Bronson, Abby; Chin, Janice; Furlong, Pat; Gordish-Dressman, Heather; Habeeb-Louks, Elizabeth; Henricson, Erik; Kroger, Hans; Lynn, Charles; Lynn, Stephen; Martin, Dana; Nuckolls, Glen; Rooney, William; Romero, Klaus; Sweeney, Lee; Vandenborne, Krista; Walter, Glenn; Wolff, Jodi; Wong, Brenda; McDonald, Craig M.; Duchenne Regulatory Science Consortium, Imaging-DMD Consortium and the CINRG Investigators, members of the

2017-01-01

Introduction: The Duchenne Regulatory Science Consortium (D-RSC) was established to develop tools to accelerate drug development for DMD.  The resulting tools are anticipated to meet validity requirements outlined by qualification/endorsement pathways at both the U.S. Food and Drug Administration (FDA) and European Medicines Administration (EMA), and will be made available to the drug development community. The initial goals of the consortium include the development of a disease progression model, with the goal of creating a model that would be used to forecast changes in clinically meaningful endpoints, which would inform clinical trial protocol development and data analysis.  Methods: In April of 2016 the consortium and other experts met to formulate plans for the development of the model.  Conclusions: Here we report the results of the meeting, and discussion as to the form of the model that we plan to move forward to develop, after input from the regulatory authorities. PMID:28228973

Definition of Intervener Services and Interveners in Educational Settings. Technical Report

ERIC Educational Resources Information Center

National Consortium on Deaf-Blindness, 2013

2013-01-01

This technical report synthesizes the process and information used by National Consortium on Deaf-Blindness (NCDB) in the development of a consistently applied definition of intervener services. It addresses challenges and questions, provides comparisons between interveners and paraprofessionals, and offers definitions, roles and concepts used by…

Legislative Priorities for the 105th Congress.

ERIC Educational Resources Information Center

National Association of State Directors of Vocational Technical Education Consortium.

The National Association of State Directors of Vocational Technical Education Consortium (NASDVTEC) supports enactment of legislation that is dedicated solely to vocational-technical education (VTE). NASDVTEC urges the 105th Congress to build on the existing foundation of a strong state role in VTE by drafting legislation that achieves the…

Microwave monolithic integrated circuit-related metrology at the National Institute of Standards and Technology

NASA Astrophysics Data System (ADS)

Reeve, Gerome; Marks, Roger; Blackburn, David

1990-12-01

How the National Institute of Standards and Technology (NIST) interacts with the GaAs community and the Defense Advanced Research Projects Agency microwave monolithic integrated circuit (MMIC) initiative is described. The organization of a joint industry and government laboratory consortium for MMIC-related metrology research is described along with some of the initial technical developments at NIST done in support of the consortium.

Survey of Maritime Experiences in Reduced Workload and Staffing

DTIC Science & Technology

1999-07-01

flexibility. National Technical University of Athens. ATOMOS (Advanced Technology to optimize manpower onboard ships) Project Rationale. (1996) http...applied R&D in this area, sponsored project ATOMOS , within its EURET transport R&D programme. ATOMOS consists of a consortium of 9 partners from 4 EU...period December 1994- December 1995) The THAMES Consortium consisted of the partners of two EURET consortia: ATOMOS and MASIS. Collectively, 21 partners

Verification and Validation Process for Progressive Damage and Failure Analysis Methods in the NASA Advanced Composites Consortium

NASA Technical Reports Server (NTRS)

Wanthal, Steven; Schaefer, Joseph; Justusson, Brian; Hyder, Imran; Engelstad, Stephen; Rose, Cheryl

2017-01-01

The Advanced Composites Consortium is a US Government/Industry partnership supporting technologies to enable timeline and cost reduction in the development of certified composite aerospace structures. A key component of the consortium's approach is the development and validation of improved progressive damage and failure analysis methods for composite structures. These methods will enable increased use of simulations in design trade studies and detailed design development, and thereby enable more targeted physical test programs to validate designs. To accomplish this goal with confidence, a rigorous verification and validation process was developed. The process was used to evaluate analysis methods and associated implementation requirements to ensure calculation accuracy and to gage predictability for composite failure modes of interest. This paper introduces the verification and validation process developed by the consortium during the Phase I effort of the Advanced Composites Project. Specific structural failure modes of interest are first identified, and a subset of standard composite test articles are proposed to interrogate a progressive damage analysis method's ability to predict each failure mode of interest. Test articles are designed to capture the underlying composite material constitutive response as well as the interaction of failure modes representing typical failure patterns observed in aerospace structures.

The ISPRS Student Consortium: From launch to tenth anniversary

NASA Astrophysics Data System (ADS)

Kanjir, U.; Detchev, I.; Reyes, S. R.; Akkartal Aktas, A.; Lo, C. Y.; Miyazaki, H.

2014-04-01

The ISPRS Student Consortium is an international organization for students and young professionals in the fields of photogrammetry, remote sensing, and the geospatial information sciences. Since its start ten years ago, the number of members of the Student Consortium has been steadily growing, now reaching close to 1000. Its increased popularity, especially in recent years, is mainly due to the organization's worldwide involvement in student matters. The Student Consortium has helped organize numerous summer schools, youth forums, and student technical sessions at ISPRS sponsored conferences. In addition, the organization publishes a newsletter, and hosts several social media outlets in order to keep its global membership up-to-date on a regular basis. This paper will describe the structure of the organization, and it will give some example of its past student related activities.

Massachusetts Institute of Technology Consortium Agreement

DTIC Science & Technology

1999-03-01

In this, our second progress report of the Phase Two Home Automation and Healthcare Consortium at the Brit and Alex d’Arbeloff Laboratory for...Covered here are the diverse fields of home automation and healthcare research, ranging from human modeling, patient monitoring, and diagnosis to new...sensors and actuators, physical aids, human-machine interface and home automation infrastructure. These results will be presented at the upcoming General Assembly of the Consortium held on October 27-October 30, 1998 at MIT.

District, Union, and Community Collaboration: Massachusetts Consortium for Innovative Education Assessment

ERIC Educational Resources Information Center

Kelly, Dianne; Fearing, Erik

2017-01-01

While Massachusetts has received accolades for its high scores on the National Assessment for Educational Progress (NAEP) and Program for International Student Assessment (PISA) tests, absolute results from standardized tests tend to correlate strongly with family income and parental education. The Massachusetts Consortium for Innovative Education…

The Historically Black Colleges and Universities/Minority Institutions Environmental Technology Consortium annual report 1994--1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-07-01

The HBCU/MI ET Consortium was established in January 1990, through a Memorandum of Understanding (MOU) among its member institutions. This group of research oriented Historically Black Colleges and Universities and Minority Institutions (HBCU/MIs) agreed to work together to initiate or revise education programs, develop research partnerships with public and private sector organizations, and promote technology development to address the nation`s critical environmental contamination problems. The Consortium`s Research, Education and Technology Transfer (RETT) Plan became the working agenda. The Consortium is a resource for collaboration among the member institutions and with federal an state agencies, national and federal laboratories, industries, (includingmore » small businesses), majority universities, and two and four-year technical colleges. As a group of 17 institutions geographically located in the southern US, the Consortium is well positioned to reach a diverse group of women and minority populations of African Americans, Hispanics and American Indians. This Report provides a status update on activities and achievements in environmental curriculum development, outreach at the K--12 level, undergraduate and graduate education, research and development, and technology transfer.« less

Promoting Work-Based Learning: Efforts in Connecticut and Kentucky

ERIC Educational Resources Information Center

Alliance for Excellent Education, 2012

2012-01-01

In the summer of 2012, the National Association of State Directors of Career Technical Education Consortium (NASDCTEc) and the Alliance for Excellent Education conducted a survey of State Directors of Career Technical Education (CTE) to gauge state efforts to better connect CTE with a larger college- and career-readiness agenda. Survey questions…

Building a Foundational Model for Credit for Prior Learning. Strategies for Transformative Change

ERIC Educational Resources Information Center

Kamps, A.; Loritz, T.; Schaff, E.; Richie, D.

2016-01-01

"Making the Future: The Wisconsin Strategy," under the leadership of Northeast Wisconsin Technical College (NWTC), received a Round Two U.S. Department of Labor Trade Adjustment Assistance for Community College and Career Training (TAACCCT) grant. The consortium brought together all 16 colleges in the Wisconsin Technical College System…

Fishing for teratogens: a consortium effort for a harmonized zebrafish developmental toxicology assay.

PubMed

Ball, Jonathan S; Stedman, Donald B; Hillegass, Jedd M; Zhang, Cindy X; Panzica-Kelly, Julie; Coburn, Aleasha; Enright, Brian P; Tornesi, Belen; Amouzadeh, Hamid R; Hetheridge, Malcolm; Gustafson, Anne-Lee; Augustine-Rauch, Karen A

2014-05-01

A consortium of biopharmaceutical companies previously developed an optimized Zebrafish developmental toxicity assay (ZEDTA) where chorionated embryos were exposed to non-proprietary test compounds from 5 to 6 h post fertilization and assessed for morphological integrity at 5 days post fertilization. With the original 20 test compounds, this achieved an overall predictive value for teratogenicity of 88% of mammalian in vivo outcome [Gustafson, A. L., Stedman, D. B., Ball, J., Hillegass, J. M., Flood, A., Zhang, C. X., Panzica-Kelly, J., Cao, J., Coburn, A., Enright, B. P., et al. (2012). Interlaboratory assessment of a harmonized Zebrafish developmental toxicology assay-Progress report on phase I. Reprod. Toxicol. 33, 155-164]. In the second phase of this project, 38 proprietary pharmaceutical compounds from four consortium members were evaluated in two laboratories using the optimized method using either pond-derived or cultivated-strain wild-type Zebrafish embryos at concentrations up to 100μM. Embryo uptake of all compounds was assessed using liquid chromatography-tandem mass spectrometry. Twenty eight of 38 compounds had a confirmed embryo uptake of >5%, and with these compounds the ZEDTA achieved an overall predictive value of 82% and 65% at the two respective laboratories. When low-uptake compounds (≤ 5%) were retested with logarithmic concentrations up to 1000μM, the overall predictivity across all 38 compounds was 79% and 62% respectively, with the first laboratory achieving 74% sensitivity (teratogen detection) and 82% specificity (non-teratogen detection) and the second laboratory achieving 63% sensitivity (teratogen detection) and 62% specificity (non-teratogen detection). Subsequent data analyses showed that technical differences rather than strain differences were the primary contributor to interlaboratory differences in predictivity. Based on these results, the ZEDTA harmonized methodology is currently being used for compound assessment at lead optimization stage of development by 4/5 of the consortium companies.

Inner-City Energy and Environmental Education Consortium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-06-11

The numbers of individuals with adequate education and training to participate effectively in the highly technical aspects of environmental site cleanup are insufficient to meet the increasing demands of industry and government. Young people are particularly sensitive to these issues and want to become better equipped to solve the problems which will confront them during their lives. Educational institutions, on the other hand, have been slow in offering courses and curricula which will allow students to fulfill these interests. This has been in part due to the lack of federal funding to support new academic programs. This Consortium has beenmore » organized to initiate focused educational effort to reach inner-city youth with interesting and useful energy and environmental programs which can lead to well-paying and satisfying careers. Successful Consortium programs can be replicated in other parts of the nation. This report describes a pilot program in Washington, DC, Philadelphia, and Baltimore with the goal to attract and retain inner-city youth to pursue careers in energy-related scientific and technical areas, environmental restoration, and waste management.« less

The Research Consortium, 1977-2010: Contributions, Milestones, and Trends

ERIC Educational Resources Information Center

Cardinal, Bradley J.; Claman, Gayle

2010-01-01

Research and innovation are a cornerstone of any progressive organization. The Research Consortium (RC) has served as the principal organization fulfilling this function on behalf of the American Alliance for Health, Physical Education, Recreation and Dance (AAHPERD) throughout much of its history. The RC is an organization of approximately 5,000…

Probing Genetic Control of Swine Responses to PRRSV Infection: Current Progress of the PRRS Host Genetics Consortium

USDA-ARS?s Scientific Manuscript database

Background: Understanding the role of host genetics in resistance to porcine reproductive and respiratory syndrome virus (PRRSV) infection, and the effects of PRRS on pig health and related growth, are goals of the PRRS Host Genetics Consortium (PHGC). Methods: The project uses a nursery pig model ...

The Vocational-Technical Resource Consortia Serving Business and Industry in Ohio. Digest of Study: Operational Procedures for Successful Vocational-Technical Resource Consortia in Serving Business and Industry in Ohio.

ERIC Educational Resources Information Center

Frasier, James E.; Stanton, William

This publication reports the development of the vocational-technical resource consortia in Ohio and identifies the operational procedures associated with successful programs. Five exemplary consortia were studied in some depth; however, data were obtained from all of the 23 consortia in the state. The research indicates that the consortium is an…

Determining and Validating Barriers to Post-Secondary Vocational, Technical and Adult Education Programs in Wisconsin. Final Report.

ERIC Educational Resources Information Center

Farning, Max; Borden, Sally

A consortium of five Wisconsin Vocational, Technical, and Adult Education (VTAE) Districts (Gateway, Indianhead, Mid-State, Milwaukee, and Southwest) were utilized to identify, verify, and alleviate barriers to enrollment. A VTAE survey in 1976 identified six major reasons for individuals' failing to attend school after indicating an interest in…

The San Francisco Consortium; An Educational Association for Urban Affairs. Progress Report.

ERIC Educational Resources Information Center

San Francisco Consortium, CA.

The San Francisco Consortium was formed in the Fall of 1967 by 5 institutions: City College of San Francisco, Golden Gate College, San Francisco State College, University of California-San Francisco Medical Center and the University of San Francisco. Its primary purpose is to be the instrument through which the resources of the major local…

A strategy for providing electronic library services to members of the AGATE Consortium

NASA Technical Reports Server (NTRS)

Thompson, J. Garth

1995-01-01

In November, 1992, NASA Administrator Daniel Goldin established a Task Force to evaluate conditions which have lead to the precipitous decline of the US General Aviation System and to recommend actions needed to re-establish US leadership in General Aviation. The Task Force Report and a report by Dr. Bruce J. Holmes, Manager of the General Aviation/Commuter Office at NASA Langley Research Center provided the directions for the formation of the Advanced General Aviation Transport Experiments (AGATE), a consortium of government, industry and university committed to the revitalization of the US General Aviation Industry. One of the recommendations of the Task Force Report was that 'a central repository of information should be created to disseminate NASA research as well as other domestic and foreign aeronautical research that has been accomplished, is ongoing or is planned... A user friendly environment should be created.' This paper describes technical and logistic issues and recommends a plan for providing technical information to members of the AGATE Consortium. It is recommended that the General Aviation office establish and maintain an electronic literature page on the AGATE server. This page should provide a user friendly interface to existing technical report and index servers identified in the report and listed in the Recommendations section. A page should also be provided which gives links to Web resources. A list of specific resources is provided in the Recommendations section. Links should also be provided to a page with tips on searching, a form to provide for feedback and suggestions from users for other resources. Finally, a page should be maintained which provides pointers to other resources like the LaRCsim workstation simulation software which is avail from LaRC at no cost. The developments of the Web is very dynamic. These developments should be monitored regularly by the GA staff and links to additional resources should be provided on the server as they become available. An recommendation to NASA Headquarters should be made to establish a logically central access to all of the NASA Technical Libraries, to make these resources available both to all NASA employees and to the AGATE Consortium.

Strategic Mobility 21 Project Management Plan

DTIC Science & Technology

2006-09-29

California Association of Governments (SCAG), and other stakeholders to transform the former military installation into a modern in-land distribution node... governments , including adversary governments , and may be exported. c. This statement may not be used on technical documents that formerly were...required updates of both the ICD and the Technical Plan. SM21 has established a consortium of public and private, governmental and non

Massachusetts Institute of Technology Consortium Agreement

DTIC Science & Technology

1999-03-01

This is the third progress report of the M.I.T. Home Automation and Healthcare Consortium-Phase Two. It covers majority of the new findings, concepts...research projects of home automation and healthcare, ranging from human modeling, patient monitoring, and diagnosis to new sensors and actuators, physical...aids, human-machine interface and home automation infrastructure. This report contains several patentable concepts, algorithms, and designs.

Enhancing Transfer Effectiveness: A Model for the 1990's. First Year Report to the National Effective Transfer Consortium. Executive Summary.

ERIC Educational Resources Information Center

Berman, Paul; And Others

This first-year report of the National Effective Transfer Consortium (NETC) summarizes the progress made by the member colleges in creating standardized measures of actual and expected transfer rates and of transfer effectiveness, and establishing a database that would enable valid comparisons among NETC colleges. Following background information…

Trailblazing in East Texas: A Progress Report on the Forest Trail Library Consortium's Networking Project.

ERIC Educational Resources Information Center

Claer, Joycelyn H.

This report describes the development of the Forest Trail Library Consortium (FTLC), a network of academic, public, and school libraries in Texas. The growth of FTLC from 4 charter members to its current 16 members is traced, including details about goals and funding. The role of special interest groups (SIGs) is examined, and the goals and…

Consortium for Verification Technology Fellowship Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sadler, Lorraine E.

2017-06-01

As one recipient of the Consortium for Verification Technology (CVT) Fellowship, I spent eight days as a visiting scientist at the University of Michigan, Department of Nuclear Engineering and Radiological Sciences (NERS). During this time, I participated in multiple department and research group meetings and presentations, met with individual faculty and students, toured multiple laboratories, and taught one-half of a one-unit class on Risk Analysis in Nuclear Arms control (six 1.5 hour lectures). The following report describes some of the interactions that I had during my time as well as a brief discussion of the impact of this fellowship onmore » members of the consortium and on me/my laboratory’s technical knowledge and network.« less

ECLSS medical support activities

NASA Technical Reports Server (NTRS)

Crump, William J.; Kilgore, Melvin V., Jr.

1991-01-01

During the period from April 10, 1990 to April 9, 1991, the Consortium for the Space Life Sciences provided technical assistance to the NASA/MSFC water recovery efforts. This assistance was in the form of literature reviews, technical recommendations, and presentations. This final report summarizes the activities completed during this period and identifies those areas requiring additional efforts. The tasks which the University of Alabama in Huntsville (UAH) water recovery team addressed were either identified by MSFC technical representatives or chosen from those outlined in the subject statement of work.

The "U" in UTEP: Development of the Urban Curriculum and Its Delivery. Second Year Report to the Indiana Department of Education, Teacher Training and Licensing Advisory Committee.

ERIC Educational Resources Information Center

Sandoval, Pamela A.

This report provides an outline of the Urban Teacher Education Program (UTEP), describes curriculum development and delivery, and discusses the progress that has been made toward program goals. UTEP is a school district/university consortium for school-based professional preparation and development. Members of the consortium include: Indiana…

Health Coaching: An Update on the National Consortium for Credentialing of Health & Wellness Coaches

PubMed Central

2015-01-01

In September 2014, Global Advances in Health and Medicine editor Michele Mittelman, RN, MPH, interviewed four of the leaders in health and wellness coaching about trends in coaching and the progress of the National Consortium for Credentialing of Health & Wellness Coaches. Following are the transcripts of those interviews. Additionally, videos of the interviews are available at www.gahmj.com. PMID:25694854

The Role of Drosophila Merlin in the Control of Mitosis Exit and Development

DTIC Science & Technology

2005-07-01

Abstract presented to the 2005 CTF International Consortium for the Molecular Biology of NFl, NF2, and Schwannomatosis ). Experiments are in progress...Drosophila Spermatogenesis. Abstract presented to the 2005 CTF International Consortium for the Molecular Biology of NFl, NF2, and Schwannomatosis . We...and Schwannomatosis . By combining bioinformatics and phylogenetic approaches, we demonstrated a monophyletic origin of the merlin proteins with the

Cooperative research in coal liquefaction. Technical progress report, May 1, 1993--April 30, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huffman, G.P.

Accomplishments for the past year are presented for the following tasks: coliquefaction of coal with waste materials; catalysts for coal liquefaction to clean transportation fuels; fundamental research in coal liquefaction; and in situ analytical techniques for coal liquefaction and coal liquefaction catalysts some of the highlights are: very promising results have been obtained from the liquefaction of plastics, rubber tires, paper and other wastes, and the coliquefaction of wastes with coal; a number of water soluble coal liquefaction catalysts, iron, cobalt, nickel and molybdenum, have been comparatively tested; mossbauer spectroscopy, XAFS spectroscopy, TEM and XPS have been used to characterizemore » a variety of catalysts and other samples from numerous consortium and DOE liquefaction projects and in situ ESR measurements of the free radical density have been conducted at temperatures from 100 to 600{degrees}C and H{sub 2} pressures up to 600 psi.« less

Biomass power for rural development. Technical progress report, October 1--December 31, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuhauser, E.

The focus of the DOE/USDA sponsored biomass power for rural development project is to develop commercial energy crops for power generation by the year 2000. The New York based Salix Consortium project is a multi-partner endeavor, implemented in three stages. Phase-1, Final Design and Project Development, will conclude with the preparation of construction and/or operating permits, feedstock production plans, and contracts ready for signature. Field trials of willow (Salix) have been initiated at several locations in New York (Tully, Lockport, King Ferry, La Fayette, Massena, and Himrod) and co-firing tests are underway at Greenidge Station (NYSEG) and Dunkirk Station (NMPC).more » Phase-2 of the project will focus on scale-up of willow crop acreage, construction of co-firing facilities at Dunkirk Station (NMPC), and final modifications for Greenidge Station. Cofiring willow is also under consideration for GPU`s Seward Station where testing is underway. There will be an evaluation of the energy crop as part of the gasification trials occurring at BED`s McNeill Power Station. Phase-3 will represent fullscale commercialization of the energy crop and power generation on a sustainable basis. During the fourth quarter of 1997 the Consortium submitted a Phase-2 proposal. A few of the other more important milestones are outlined below. The first quarter of 1998 will be dominated by pre-planting activity in the spring.« less

Demonstration of Next-Generation PEM CHP Systems for Global Markets Using PBI Membrane Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vogel, John; Fritz Intwala, Katrina

Plug Power and BASF have conducted eight years of development work prior to this project, demonstrating the potential of PBI membranes to exceed many DOE technical targets. This project consisted of; 1.The development of a worldwide system architecture; 2.Stack and balance of plant module development; 3.Development of an improved, lower cost MEA electrode; 4.Receipt of an improved MEA from the EU consortium; 5.Integration of modules into a system; and 6.Delivery of system to EU consortium for additional integration of technologies and testing.

Promotores As Advocates for Community Improvement: Experiences of the Western States REACH Su Comunidad Consortium.

PubMed

Kutcher, Rachel; Moore-Monroy, Martha; Bello, Elizur; Doyle, Seth; Ibarra, Jorge; Kunz, Susan; Munoz, Rocio; Patton-Lopez, Megan; Sharkey, Joseph R; Wilger, Susan; Alfero, Charlie

2015-01-01

The REACH Su Comunidad Consortium worked with 10 communities to address disparities in access to healthy food and physical activity opportunities among Hispanic populations through policy, systems, and environmental (PSE) strategies. Community health workers took leadership roles in the implementation of PSE strategies in partnership with local multisector coalitions. This article describes the role of community health workers in PSE change, the technical and professional development support provided to the REACH Su Comunidad Communities, and highlights professional development needs of community health workers engaging in PSE strategies.

Document delivery by the Jupiter Library Consortium

NASA Technical Reports Server (NTRS)

Wessels, Robert H. A.

1994-01-01

The Jupiter library consortium consists of 4 of the leading libraries in the Netherlands. During 1993 Jupiter received 600,000 requests for copies of journal articles, or 70 percent of all external article requests in the Netherlands. Over 90 percent of the requested documents were delivered from a collection of 40,000 current international journal subscriptions. Jupiter and its affiliate libraries are non-profit organizations belonging to, and serving, the scientific and technical research community. The usage of the current journal collection of the libraries was analyzed to improve the cost/benefit ratio.

48 CFR 2052.211-71 - Technical progress report.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Technical progress report... Technical progress report. As prescribed at 2011.104-70(b), the contracting officer shall insert the... solicitation. Technical Progress Report (JAN 1993) The contractor shall provide a monthly Technical Progress...

48 CFR 2052.211-71 - Technical progress report.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Technical progress report... Technical progress report. As prescribed at 2011.104-70(b), the contracting officer shall insert the... solicitation. Technical Progress Report (JAN 1993) The contractor shall provide a monthly Technical Progress...

48 CFR 2052.211-71 - Technical progress report.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Technical progress report... Technical progress report. As prescribed at 2011.104-70(b), the contracting officer shall insert the... solicitation. Technical Progress Report (JAN 1993) The contractor shall provide a monthly Technical Progress...

48 CFR 2052.211-71 - Technical progress report.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Technical progress report... Technical progress report. As prescribed at 2011.104-70(b), the contracting officer shall insert the... solicitation. Technical Progress Report (JAN 1993) The contractor shall provide a monthly Technical Progress...

Kansas Wind Energy Consortium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gruenbacher, Don

2015-12-31

This project addresses both fundamental and applied research problems that will help with problems defined by the DOE “20% Wind by 2030 Report”. In particular, this work focuses on increasing the capacity of small or community wind generation capabilities that would be operated in a distributed generation approach. A consortium (KWEC – Kansas Wind Energy Consortium) of researchers from Kansas State University and Wichita State University aims to dramatically increase the penetration of wind energy via distributed wind power generation. We believe distributed generation through wind power will play a critical role in the ability to reach and extend themore » renewable energy production targets set by the Department of Energy. KWEC aims to find technical and economic solutions to enable widespread implementation of distributed renewable energy resources that would apply to wind.« less

ARL Arabic Dependency Treebank

DTIC Science & Technology

2016-02-10

This technical note describes the US Army Research Laboratory (ARL) Arabic Dependency Treebank (AADT) for the purpose of documenting its release. The...AADT was derived from existing Arabic treebanks distributed by the Linguistic Data Consortium using constituent-to- dependency conversion software

The financial implications of endovascular aneurysm repair in the cost containment era.

PubMed

Stone, David H; Horvath, Alexander J; Goodney, Philip P; Rzucidlo, Eva M; Nolan, Brian W; Walsh, Daniel B; Zwolak, Robert M; Powell, Richard J

2014-02-01

Endovascular aneurysm repair (EVAR) is associated with significant direct device costs. Such costs place EVAR at odds with efforts to constrain healthcare expenditures. This study examines the procedure-associated costs and operating margins associated with EVAR at a tertiary care academic medical center. All infrarenal EVARs performed from April 2011 to March 2012 were identified (n = 127). Among this cohort, 49 patients met standard commercial instruction for use guidelines, were treated using a single manufacturer device, and billed to Medicare diagnosis-related group (DRG) 238. Of these 49 patients, net technical operating margins (technical revenue minus technical cost) were calculated in conjunction with the hospital finance department. EVAR implant costs were determined for each procedure. DRG 238-associated costs and length of stay were benchmarked against other academic medical centers using University Health System Consortium 2012 data. Among the studied EVAR cohort (age 75, 82% male, mean length of stay, 1.7 days), mean technical costs totaled $31,672. Graft implants accounted for 52% of the allocated technical costs. Institutional overhead was 17% ($5495) of total technical costs. Net mean total technical EVAR-associated operating margins were -$4015 per procedure. Our institutional costs and length of stay, when benchmarked against comparable centers, remained in the lowest quartile nationally using University Health System Consortium costs for DRG 238. Stent graft price did not correlate with total EVAR market share. EVAR is currently associated with significant negative operating margins among Medicare beneficiaries. Currently, device costs account for over 50% of EVAR-associated technical costs and did not impact EVAR market share, reflecting an unawareness of cost differential among surgeons. These data indicate that EVAR must undergo dramatic care delivery redesign for this practice to remain sustainable. Copyright © 2014 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.

Primary Immune Deficiency Treatment Consortium (PIDTC) report.

PubMed

Griffith, Linda M; Cowan, Morton J; Notarangelo, Luigi D; Kohn, Donald B; Puck, Jennifer M; Pai, Sung-Yun; Ballard, Barbara; Bauer, Sarah C; Bleesing, Jack J H; Boyle, Marcia; Brower, Amy; Buckley, Rebecca H; van der Burg, Mirjam; Burroughs, Lauri M; Candotti, Fabio; Cant, Andrew J; Chatila, Talal; Cunningham-Rundles, Charlotte; Dinauer, Mary C; Dvorak, Christopher C; Filipovich, Alexandra H; Fleisher, Thomas A; Bobby Gaspar, Hubert; Gungor, Tayfun; Haddad, Elie; Hovermale, Emily; Huang, Faith; Hurley, Alan; Hurley, Mary; Iyengar, Sumathi; Kang, Elizabeth M; Logan, Brent R; Long-Boyle, Janel R; Malech, Harry L; McGhee, Sean A; Modell, Fred; Modell, Vicki; Ochs, Hans D; O'Reilly, Richard J; Parkman, Robertson; Rawlings, David J; Routes, John M; Shearer, William T; Small, Trudy N; Smith, Heather; Sullivan, Kathleen E; Szabolcs, Paul; Thrasher, Adrian; Torgerson, Troy R; Veys, Paul; Weinberg, Kenneth; Zuniga-Pflucker, Juan Carlos

2014-02-01

The Primary Immune Deficiency Treatment Consortium (PIDTC) is a network of 33 centers in North America that study the treatment of rare and severe primary immunodeficiency diseases. Current protocols address the natural history of patients treated for severe combined immunodeficiency (SCID), Wiskott-Aldrich syndrome, and chronic granulomatous disease through retrospective, prospective, and cross-sectional studies. The PIDTC additionally seeks to encourage training of junior investigators, establish partnerships with European and other International colleagues, work with patient advocacy groups to promote community awareness, and conduct pilot demonstration projects. Future goals include the conduct of prospective treatment studies to determine optimal therapies for primary immunodeficiency diseases. To date, the PIDTC has funded 2 pilot projects: newborn screening for SCID in Navajo Native Americans and B-cell reconstitution in patients with SCID after hematopoietic stem cell transplantation. Ten junior investigators have received grant awards. The PIDTC Annual Scientific Workshop has brought together consortium members, outside speakers, patient advocacy groups, and young investigators and trainees to report progress of the protocols and discuss common interests and goals, including new scientific developments and future directions of clinical research. Here we report the progress of the PIDTC to date, highlights of the first 2 PIDTC workshops, and consideration of future consortium objectives. Published by Mosby, Inc.

The journey of primary care practices to meaningful use: a Colorado Beacon Consortium study.

PubMed

Fernald, Douglas H; Wearner, Robyn; Dickinson, W Perry

2013-01-01

The Health Information Technology for Economic and Clinical Health Act of 2009 provides for incentive payments through Medicare and Medicaid for clinicians who implement electronic health records (EHRs) and use this technology meaningfully to improve patient care. There are few comprehensive descriptions of how primary care practices achieve the meaningful use of clinical data, including the formal stage 1 meaningful use requirements. Evaluation of the Colorado Beacon Consortium project included iterative qualitative analysis of practice narratives, provider and staff interviews, and separate focus groups with quality improvement (QI) advisors and staff from the regional health information exchange (HIE). Most practices described significant realignment of practice priorities and aims, which often required substantial education and training of physicians and staff. Re-engineering office processes, data collection protocols, EHRs, staff roles, and practice culture comprised the primary effort and commitment to attest to stage 1 meaningful use and subsequent meaningful use of clinical data. While realizing important benefits, practices bore a significant burden in learning the true capabilities of their EHRs with little effective support from vendors. Attestation was an important initial milestone in the process, but practices faced substantial ongoing work to use their data meaningfully for patient care and QI. Key resources were instrumental to these practices: local technical EHR expertise; collaborative learning mechanisms; and regular contact and support from QI advisors. Meeting the stage 1 requirements for incentives under Medicare and Medicaid meaningful use criteria is the first waypoint in a longer journey by primary care practices to the meaningful use of electronic data to continuously improve the care and health of their patients. The intensive re-engineering effort for stage 1 yielded practice changes consistent with larger practice aims and goals. While many of these practices are now poised to use data meaningfully, faster progress will likely come with continued local QI and technical support and planned community-wide learning.

ToxCast: EPAs Contribution to the Tox21 Consortium

EPA Science Inventory

The international community needs better predictive tools for assessing the hazards and risks of chemicals. It is technically feasible to collect bioactivity data on virtually all chemicals of potential concern ToxCast is providing a proof of concept for obtaining predictive, b...

Unvented Attic Increases Energy Efficiency and Reduces Duct Losses: Pulte Homes - Sun Lake at Banning, California

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2001-10-01

New houses in the Sun Lakes at Banning subdivision are designed by Pulte Homes with technical support from the Building Science Consortium as part of the U.S. Department of Energy's Building America Program.

Consortium for Materials Development in Space. Technical section

NASA Technical Reports Server (NTRS)

1987-01-01

Several topics related to materials development in space are discussed. Physical vapor transport crystal growth, the mass spectroscopic facility, surface coatings and catalyst production by electrodeposition, mass transfer by diffusion, electrooptical organic materials, and high temperature superconductors are among the topics covered.

Report on the CEPA activities [Consorcio Educativo para la Proteccion Ambiental/Educational Consortium for Environmental Preservation] [Final report of activities from 1998 to 2002

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cruz, Miriam

This report compiles the instances of scientific, educational, and institutional cooperation on environmental issues and other activities in which CEPA was engaged during the past five years, and includes several annual reports and meeting summaries. CEPA is a collaborative international consortium that brings together higher education institutions with governmental agencies, research laboratories, and private sector entities. CEPA's mission is to strengthen the technical, professional, and educational environmental infrastructure in the United States and Latin America. The CEPA program includes curriculum development, student exchange, faculty development, and creation of educational materials, joint research, and other cooperative activities. CEPA's goals are accomplishedmore » by actively working with Hispanic-serving institutions of higher education in the United States, in collaboration with institutions of higher education in Latin America and other Consortium members to deliver competitive environmental programs.« less

Developing Learning Progressions in Support of the New Science Standards: A RAPID Workshop Series

ERIC Educational Resources Information Center

Rogat, Aaron

2011-01-01

The hypothetical learning progressions presented here are the products of the deliberations of two working groups of science education researchers, each group also including a state science curriculum supervisor, organized by the Consortium for Policy Research in Education (CPRE), with support from the National Science Foundation. Their charge was…

CISNET: Model Documentation

Cancer.gov

The Publications pages provide lists of all CISNET publications since the inception of CISNET. Publications are listed by Cancer Site or by Research Topic. The Publication Support and Modeling Resources pages provides access to technical modeling information, raw data, and publication extensions stemming from the work of the CISNET consortium.

V-TECS Guide for Bookkeeping/Accounting/Payroll Clerk.

ERIC Educational Resources Information Center

Gregory, Margaret R.; Benson, Robert T.

This guide, an extension of the Vocational-Technical Education Consortium of States (V-TECS) catalog, includes such considerations as background information, decision-making skills, attitudes, and learning methods surrounding the occupations of bookkeeper/accountant/payroll clerk. The guide provides job-relevant task, performance objectives,…

Contemporary Business Administration Curricula

ERIC Educational Resources Information Center

Gleason, James R.

2006-01-01

The National Association of State Directors of Career Technical Education Consortium (NASDCTEc) career clusters initiative was designed to research and foster development of curicula and assessments for each of 16 broad occupational groupings known as career clusters. These clusters encompass a broad range of careers, ranging from agriculture to…

CISNET: Resources

Cancer.gov

The Publications pages provide lists of all CISNET publications since the inception of CISNET. Publications are listed by Cancer Site or by Research Topic. The Publication Support and Modeling Resources pages provides access to technical modeling information, raw data, and publication extensions stemming from the work of the CISNET consortium.

TECHcitement: Advances in Technological Education, 2006

ERIC Educational Resources Information Center

American Association of Community Colleges (NJ1), 2006

2006-01-01

This publication includes 13 articles: (1) ATE [Advanced Technological Education] Attuned to Global Competition; (2) Materials Science Center Supplies Information on Often-Overlooked Field; (3) CSEC [Cyber Security Education Consortium] Builds Corps of Cyber Technicians; (4) KCTCS [Kentucky Community and Technical College System] Is U.S. Partner…

Support of Gulf of Mexico Hydrate Research Consortium: Activities of Support Establishment of a Sea Floor Monitoring Station Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Robert Woolsey; Thomas McGee; Carol Lutken

2008-05-31

The Gulf of Mexico Hydrates Research Consortium (GOM-HRC) was established in 1999 to assemble leaders in gas hydrates research that shared the need for a way to conduct investigations of gas hydrates and their stability zone in the Gulf of Mexico in situ on a more-or-less continuous basis. The primary objective of the group is to design and emplace a remote monitoring station or sea floor observatory (SFO) on the sea floor in the northern Gulf of Mexico, in an area where gas hydrates are known to be present at, or just below, the sea floor and to discover themore » configuration and composition of the subsurface pathways or 'plumbing' through which fluids migrate into and out of the hydrate stability zone (HSZ) to the sediment-water interface. Monitoring changes in this zone and linking them to coincident and perhaps consequent events at the seafloor and within the water column is the eventual goal of the Consortium. This mission includes investigations of the physical, chemical and biological components of the gas hydrate stability zone - the sea-floor/sediment-water interface, the near-sea-floor water column, and the shallow subsurface sediments. The eventual goal is to monitor changes in the hydrate stability zone over time. Establishment of the Consortium succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among those involved in gas hydrates research. Complementary expertise, both scientific and technical, has been assembled to promote innovative methods and construct necessary instrumentation. Following extensive investigation into candidate sites, Mississippi Canyon 118 (MC118) was chosen by consensus of the Consortium at their fall, 2004, meeting as the site most likely to satisfy all criteria established by the group. Much of the preliminary work preceding the establishment of the site - sensor development and testing, geophysical surveys, and laboratory studies - has been reported in agency documents including the Final Technical Report to DOE covering Cooperative Agreement DEFC26-00NT40920 and Semiannual Progress Reports for this award, DE-FC26-02NT41628. Initial components of the observatory, a probe that collects pore-fluid samples and another that records sea floor temperatures, were deployed in MC118 in May of 2005. Follow-up deployments, planned for fall 2005, had to be postponed due to the catastrophic effects of Hurricane Katrina (and later, Rita) on the Gulf Coast. SFO completion, now anticipated for 2009-10, has, therefore, been delayed. Although delays caused scheduling and deployment difficulties, many sensors and instruments were completed during this period. Software has been written that will accommodate the data that the station retrieves, when it begins to be delivered. In addition, new seismic data processing software has been written to treat the peculiar data to be received by the vertical line array (VLA) and additional software has been developed that will address the horizontal line array (HLA) data. These packages have been tested on data from the test deployments of the VLA and on data from other, similar, areas of the Gulf (in the case of the HLA software). During the life of this Cooperative Agreement (CA), the CMRET conducted many cruises. Early in the program these were executed primarily to survey potential sites and test sensors and equipment being developed for the SFO. When MC118 was established as the observatory site, subsequent cruises focused on this location. Beginning in 2005 and continuing to the present, 13 research cruises to MC118 have been conducted by the Consortium. During September, 2006, the Consortium was able to secure 8 days aboard the R/V Seward Johnson with submersible Johnson SeaLink, a critical chapter in the life of the Observatory project as important documentation, tests, recoveries and deployments were accomplished during this trip (log appended). Consortium members have participated materially in a number of additional cruises including several of the NIUST autonomous underwater vehicle (AUV), Eagle Ray. Activities reports summarize cruise activities, including objectives, how they were met or not met, and challenges. Deployment cruises are scheduled for 2009 that are designed to complete installation of the major observatory components.« less

Standardization efforts in IP telephony

NASA Astrophysics Data System (ADS)

Sengodan, Senthil; Bansal, Raj

1999-11-01

The recent interest in IP telephony has led to a tremendous increase of standardization activities in the area. The three main standards bodies in the area of IP telephony are the International Telecommunication Union's (ITU-T) Study Group (SG) 16, the Internet Engineering Task Force (IETF) and the European Telecommunication Standards Institute's (ETSI) TIPHON project. In addition, forums such as the International Multimedia Teleconferencing Consortium (IMTC), the Intelligent Network Forum (INF), the International Softswitch Consortium (ISC), the Electronic Computer Telephony Forum (ECTF), and the MIT's Internet Telephony Consortium (ITC) are looking into various other aspects that aim at the growth of this industry. This paper describes the main tasks (completed and in progress) undertaken by these organizations. In describing such work, an overview of the underlying technology is also provided.

CFD Aerothermodynamic Characterization Of The IXV Hypersonic Vehicle

NASA Astrophysics Data System (ADS)

Roncioni, P.; Ranuzzi, G.; Marini, M.; Battista, F.; Rufolo, G. C.

2011-05-01

In this paper, and in the framework of the ESA technical assistance activities for IXV project, the numerical activities carried out by ASI/CIRA to support the development of Aerodynamic and Aerothermodynamic databases, independent from the ones developed by the IXV Industrial consortium, are reported. A general characterization of the IXV aerothermodynamic environment has been also provided for cross checking and verification purposes. The work deals with the first year activities of Technical Assistance Contract agreed between the Italian Space Agency/CIRA and ESA.

V-TECS Criterion-Referenced Test Item Bank for Radiologic Technology Occupations.

ERIC Educational Resources Information Center

Reneau, Fred; And Others

This Vocational-Technical Education Consortium of States (V-TECS) criterion-referenced test item bank provides 696 multiple-choice items and 33 matching items for radiologic technology occupations. These job titles are included: radiologic technologist, chief; radiologic technologist; nuclear medicine technologist; radiation therapy technologist;…

The Border Health Consortium of the Californias—Forming a Binational (California–Baja California) Entity to Address the Health of a Border Region: A Case Study

PubMed Central

Kozo, Justine; Zapata-Garibay, Rogelio; Rangel-Gomez, María Gudelia; Fernandez, April; Hirata-Okamoto, Ricardo; Wooten, Wilma; Vargas-Ojeda, Adriana; Jiménez, Barbara; Zepeda-Cisneros, Hector; Matthews, Charles Edwards

2018-01-01

The California–Baja California border region is one of the most frequently traversed areas in the world with a shared population, environment, and health concerns. The Border Health Consortium of the Californias (the “Consortium”) was formed in 2013 to bring together leadership working in the areas of public health, health care, academia, government, and the non-profit sector, with the goal of aligning efforts to improve health outcomes in the region. The Consortium utilizes a Collective Impact framework which supports a shared vision for a healthy border region, mutually reinforcing activities among member organizations and work groups, and a binational executive committee that ensures continuous communication and progress toward meeting its goals. The Consortium is comprised of four binational work groups which address human immunodeficiency virus, tuberculosis, obesity, and mental health, all mutual priorities in the border region. The Consortium holds two general binational meetings each year alternating between California and Baja California. The work groups meet regularly to share information, resources and provide binational training opportunities. Since inception, the Consortium has been successful in strengthening binational communication, coordination, and collaboration by providing an opportunity for individuals to meet one another, learn about each other systems, and foster meaningful relationships. With binational leadership support and commitment, the Consortium could certainly be replicated in other border jurisdictions both nationally and internationally. The present article describes the background, methodology, accomplishments, challenges, and lessons learned in forming the Consortium. PMID:29404318

Internationalization and Faculty-Led Service Learning

ERIC Educational Resources Information Center

Bradshaw, Geoffrey W.

2013-01-01

In 2010, Madison Area Technical College (Madison College), a comprehensive community college in Madison, Wisconsin, was selected by the U.S. Department of State, Bureau of Education and Cultural Affairs (ECA) to head a consortium project to expand the capacity of community colleges to offer study-abroad programs. The project focuses on…

Laser System Technician. A Catalog of Performance Objectives and Performance Guides.

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee. Div. of Vocational, Adult, and Community Education.

This Vocational-Technical Education Consortium of States (V-TECS) catalog contains the state-of-the-art tasks and standards of performance for the occupation of laser system technician. It provides the curriculum specialist or instructor with the foundation for instructional development. Performance objectives and performance guides are provided…

Using Computer Conferencing Techniques To Maximize Student Learning.

ERIC Educational Resources Information Center

Norton, Robert E.; Stammen, Ronald M.

The Consortium for the Development of Professional Materials for Vocational Education at Ohio State University was organized in 1978 for the purpose of developing high-quality curriculum materials for training leadership personnel in vocational and technical education in the United States, and to pilot test and demonstrate new instructional…

Observations regarding the Development of Occupational/Skill Clusters.

ERIC Educational Resources Information Center

McCage, Ronald D.

This paper presents an overview and suggestions about the development of occupational and skill clusters by the Vocational-Technical Education Consortium of States (V-TECS), based on the observations of the executive director of the organization. Aspects reviewed include the following: development of occupational and skill clusters; classification…

Biomass power for rural development. Technical progress report, January 1, 1997--March 31, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuhauser, E.

Detailed task progress reports and schedules are provided for the DOE/USDA sponsored Biomass Power for Rural Development project. The focus of the project is on developing commercial energy crops for power generation by the year 2000. The New York based Salix Consortium project is a multi-partner endeavor, implemented in three stages. Phase-1, Final Design and Project Development, will conclude with the preparation of construction and/or operating permits, feedstock production plans, and contracts ready for signature. Field trials of willow (Salix) have been initiated at several locations in New York (Tully, Lockport, King Ferry, La Fayette, Massena, and Himrod) and co-firingmore » tests are underway at Greenidge Station (NYSEG) and Dunkirk Station (NMPC). Phase-II of the project will focus on scale-up of willow crop acreage, construction of co-firing facilities at Dunkirk Station (NMPC), and final modifications for Greenidge Station. Cofiring willow is also under consideration for GPU`s Seward Station where testing is under way. There will be an evaluation of the energy crop as part of the gasification trials occurring at BED`s McNeill power station. Phase-III will represent fullscale commercialization of the energy crop and power generation on a sustainable basis.« less

Biomass power for rural development. Technical progress report, April 1, 1997--June 30, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuhauser, E.

Detailed task progress reports and schedules are provided for the DOE/USDA sponsored Biomass Power for Rural Development project. The focus of the project is on developing commercial energy crops for power generation by the year 2000. The New York based Salix Consortium project is a multi-partner endeavor, implemented in three stages. Phase-I, Final Design and Project Development, will conclude with the preparation of construction and/or operating permits, feedstock production plans, and contracts ready for signature. Field trials of willow (Salix) have been initiated at several locations in New York (Tully, Lockport, King Ferry, La Fayette, Massena, and Himrod) and co-firingmore » tests are underway at Greenidge Station (NYSEG) and Dunkirk Station (NMPC). Phase-H of the project will focus on scale-up of willow crop acreage, construction of co-firing facilities at Dunkirk Station (NMPC), and final modifications for Greenidge Station. Cofiring willow is also under consideration for GPU`s Seward Station where testing is under way. There will be an evaluation of the energy crop as part of the gasification trials occurring at BED`s McNeill power station. Phase-III will represent fullscale commercialization of the energy crop and power generation on a sustainable basis.« less

Development of a consortium for water security and safety: Planning for an early warning system

USGS Publications Warehouse

Clark, R.M.; Adam, N.R.; Atluri, V.; Halem, M.; Vowinkel, E.F.; ,

2004-01-01

The events of September 11, 2001 have raised concerns over the safety and security of the Nation's critical infrastructure including water and waste water systems. In June 2002, the U.S. EPA's Region II Office (New York City), in response to concerns over water security, in collaboration with Rutgers University agreed to establish a Regional Drinking Water Security and Safety Consortium (RDWSSC). Members of the consortium include: Rutgers University's Center for Information Management, Integration and Connectivity (CIMIC), American Water (AW), the Passaic Valley Water Commission (PVWC), the North Jersey District Water Supply Commission (NJDWSC), the N.J. Department of Environmental Protection, the U.S. Geological Survey (USGS), and the U.S. Environmental Protection Agencies, Region II Office. In December of 2002 the consortium members signed a memorandum of understanding (MOU) to pursue activities to enhance regional water security. Development of an early warning system for source and distributed water was identified as being of primary importance by the consortium. In this context, an early warning system (EWS) is an integrated system of monitoring stations located at strategic points in a water utilities source waters or in its distribution system, designed to warn against contaminants that might threaten the health and welfare of drinking water consumers. This paper will discuss the consortium's progress in achieving these important objectives.

Midwest Transportation Consortium annual progress report : October 2001.

DOT National Transportation Integrated Search

2001-10-01

From the Director: Transportation assets are tremendously important from the perspective the performance of our national, : state, and regional economies. Few people comprehend the great impact it has on the overall economy. : Literally trillions of ...

Implementing a Military Transitions Program. Strategies for Transformative Change

ERIC Educational Resources Information Center

Mikulka, D.; Remy, K.; Smith, C.; Fox, H. L.

2016-01-01

In 2011, Washburn University of Topeka, Kansas was awarded a $19.6 million Round 1 TAACCCT grant through the Department of Labor to provide industry-relevant, hands-on training for high-demand, high-wage careers. The consortium, Technical Retraining to Achieve Credentials (TRAC-7), was led by Washburn University, and included seven Kansas…

A Public-Private Consortium Advances Cardiac Safety Evaluation: Achievements of the HESI Cardiac Safety Technical Committee

EPA Science Inventory

The evaluation of cardiovascular side-effects is a critical element in the development of all new drugs and chemicals. Cardiac safety issues have been and continue to be a major cause of attrition and withdrawal due to Adverse Drug Reactions (ADRs) in pharmaceutical drug developm...

V-TECS Guide for Medical Assistant.

ERIC Educational Resources Information Center

South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

This V-TECS (Vocational-Technical Consortium of States) Guide is an extension or continuation of the V-TECS catalog for the occupation of medical assistant. The guide is designed to help South Carolina teachers to promote the art of learning while teaching subject matter. The guide addresses the three domains of learning: psychomotor, cognitive,…

77 FR 25143 - Announcement of Meeting on “Developing Standard Requirements for Fatigue Performance of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-27

... meeting. SUMMARY: The National Institute of Standards and Technology (NIST) invites interested parties to..., [email protected]nist.gov . SUPPLEMENTARY INFORMATION: The goal of the consortium will include determining... planning and standard development would be conducted by NIST staff along with at least one technical...

Facilitate, Collaborate, Educate: the Role of the IRIS Consortium in Supporting National and International Research in Seismology (Invited)

NASA Astrophysics Data System (ADS)

Simpson, D. W.; Beck, S. L.

2009-12-01

Over the twenty-five years since its founding in 1984, the IRIS Consortium has contributed in fundamental ways to change the practice and culture of research in seismology in the US and worldwide. From an original founding group of twenty-two U.S. academic institutions, IRIS membership has now grown to 114 U.S. Member Institutions, 20 Educational Affiliates and 103 Foreign Affiliates. With strong support from the National Science Foundation, additional resources provided by other federal agencies, close collaboration with the U.S. Geological Survey and many international partners, the technical resources of the core IRIS programs - the Global Seismographic Network (GSN), the Program for Array Seismic Studies of the Continental Lithosphere (PASSCAL), the Data Management System (DMS) and Education and Outreach - have grown to become a major national and international source of experimental data for research on earthquakes and Earth structure, and a resource to support education and outreach to the public. While the primary operational focus of the Consortium is to develop and maintain facilities for the collection of seismological data for basic research, IRIS has become much more than an instrument facility. It has become a stimulus for collaboration between academic seismological programs and a focus for their interactions with national and international partners. It has helped establish the academic community as a significant contributor to the collection of data and an active participant in global research and monitoring. As a consortium of virtually all of the Earth science research institutions in the US, IRIS has helped coordinate the academic community in the development of new initiatives, such as EarthScope, to strengthen the support for science and argue for the relevance of seismology and its use in hazard mitigation. The early IRIS pioneers had the foresight to carefully define program goals and technical standards for the IRIS facilities that have stood the test of time. Many of these technical standards for equipment and data exchange have extended to become de-facto global standards and influenced instrument development and network practices throughout the world. A governance structure for the Consortium was created that continues to encourage strong community guidance in the operation and evolution of IRIS programs. From the outset, there was a commitment to maintaining a complete archive of all IRIS data, with significant emphasis on metadata and quality control. Building on long-standing traditions of collaboration in seismological research, an explicit IRIS policy of free and open data exchange has expanded the culture of data sharing among it members, which, through example, encouragement and support, has extended to influence the data policies of numerous other organizations in seismology and the Earth sciences. The technical revolution in sensors, communications and data collection that accompanied the early development of IRIS is now available to the entire world. The challenge for IRIS and the seismology community in the decades ahead will be to encourage the implementation of these technologies, along with appropriate training and resources, to further the research community’s endeavors to understand the structure and evolution of our planet and apply that knowledge to the mitigation of earthquake hazards.

Cancer Systems Biology Consortium | Informatics Technology for Cancer Research (ITCR)

Cancer.gov

Cancer is a complex disease system involving multiple molecular, genetic, and cellular events. From its early initiation through progression and metastasis, cancer can adapt and evolve as a result of both internal and external signals. These properties make cancer difficult to predict, prevent, and treat. There has been significant progress in characterizing the genetics of cancer, as well as the downstream effects on the molecular and cellular pathways that are critical for the initiation and progression of cancer.

76 FR 21712 - Meeting of the Ocean Research and Resources Advisory Industry Sub-Panel

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-18

... creative problem-solving to overcome impediments to industry progress toward deploying operational projects... held at the Consortium for Ocean Leadership, 1201 New York Avenue, NW., 4th Floor, Washington, DC 20005...

FIN-EPOS - Finnish national initiative of the European Plate Observing System: Bringing Finnish solid Earth infrastructures into EPOS

NASA Astrophysics Data System (ADS)

Vuorinen, Tommi; Korja, Annakaisa

2017-04-01

FIN-EPOS consortium is a joint community of Finnish national research institutes tasked with operating and maintaining solid-earth geophysical and geological observatories and laboratories in Finland. These national research infrastructures (NRIs) seek to join EPOS research infrastructure (EPOS RI) and further pursue Finland's participation as a founding member in EPOS ERIC (European Research Infrastructure Consortium). Current partners of FIN-EPOS are the University of Helsinki (UH), the University of and Oulu (UO), Finnish Geospatial Research Institute (FGI) of the National Land Survey (NLS), Finnish Meteorological Institute (FMI), Geological Survey of Finland (GTK), CSC - IT Center for Science and MIKES Metrology at VTT Technical Research Centre of Finland Ltd. The consortium is hosted by the Institute of Seismology, UH (ISUH). The primary purpose of the consortium is to act as a coordinating body between various NRIs and the EPOS RI. FIN-EPOS engages in planning and development of the national EPOS RI and will provide support in EPOS implementation phase (IP) for the partner NRIs. FIN-EPOS also promotes the awareness of EPOS in Finland and is open to new partner NRIs that would benefit from participating in EPOS. The consortium additionally seeks to advance solid Earth science education, technologies and innovations in Finland and is actively engaging in Nordic co-operation and collaboration of solid Earth RIs. The main short term objective of FIN-EPOS is to make Finnish geoscientific data provided by NRIs interoperable with the Thematic Core Services (TCS) in the EPOS IP. Consortium partners commit into applying and following metadata and data format standards provided by EPOS. FIN-EPOS will also provide a national Finnish language web portal where users are identified and their user rights for EPOS resources are defined.

(Re)Building a Kidney

PubMed Central

Carroll, Thomas J.; Cleaver, Ondine; Gossett, Daniel R.; Hoshizaki, Deborah K.; Hubbell, Jeffrey A.; Humphreys, Benjamin D.; Jain, Sanjay; Jensen, Jan; Kaplan, David L.; Kesselman, Carl; Ketchum, Christian J.; Little, Melissa H.; McMahon, Andrew P.; Shankland, Stuart J.; Spence, Jason R.; Valerius, M. Todd; Wertheim, Jason A.; Wessely, Oliver; Zheng, Ying; Drummond, Iain A.

2017-01-01

(Re)Building a Kidney is a National Institute of Diabetes and Digestive and Kidney Diseases-led consortium to optimize approaches for the isolation, expansion, and differentiation of appropriate kidney cell types and the integration of these cells into complex structures that replicate human kidney function. The ultimate goals of the consortium are two-fold: to develop and implement strategies for in vitro engineering of replacement kidney tissue, and to devise strategies to stimulate regeneration of nephrons in situ to restore failing kidney function. Projects within the consortium will answer fundamental questions regarding human gene expression in the developing kidney, essential signaling crosstalk between distinct cell types of the developing kidney, how to derive the many cell types of the kidney through directed differentiation of human pluripotent stem cells, which bioengineering or scaffolding strategies have the most potential for kidney tissue formation, and basic parameters of the regenerative response to injury. As these projects progress, the consortium will incorporate systematic investigations in physiologic function of in vitro and in vivo differentiated kidney tissue, strategies for engraftment in experimental animals, and development of therapeutic approaches to activate innate reparative responses. PMID:28096308

A SUGGESTED CURRICULUM GUIDE FOR ELECTRO-MECHANICAL TECHNOLOGY ORIENTED SPECIFICALLY TO THE COMPUTER AND BUSINESS MACHINE FIELDS. INTERIM REPORT.

ERIC Educational Resources Information Center

LESCARBEAU, ROLAND F.; AND OTHERS

A SUGGESTED POST-SECONDARY CURRICULUM GUIDE FOR ELECTRO-MECHANICAL TECHNOLOGY ORIENTED SPECIFICALLY TO THE COMPUTER AND BUSINESS MACHINE FIELDS WAS DEVELOPED BY A GROUP OF COOPERATING INSTITUTIONS, NOW INCORPORATED AS TECHNICAL EDUCATION CONSORTIUM, INCORPORATED. SPECIFIC NEEDS OF THE COMPUTER AND BUSINESS MACHINE INDUSTRY WERE DETERMINED FROM…

The Texas Tech Prep Consortia: Strategies for Advancing Academic and Technical Education.

ERIC Educational Resources Information Center

Hensley, Oliver D., Ed.; And Others

This book contains 30 chapters on the tech prep initiative in Texas: "The Identity of Tech Prep in Texas" (Tunstall); "A Snap-Shot of the Impact of the Tech Prep Initiative in the Governor's 24 Planning Regions" (Brown); "The Tech Prep Consortium Directors: The Architects for the Future of Texas" (Hensley et al.);…

Interfacing Simulations with Training Content

DTIC Science & Technology

2006-09-01

a panelist at numerous international training and elearning conferences, ADL Plugfests and IMS Global Learning Consortium Open Technical Forums. Dr...communication technologies has enabled higher quality learning to be made available through increasingly sophisticated modes of presentation. Traditional...However, learning is a comprehensive process which does not simply consist of the transmission and learning of content. While simulations offer the

The Evolution of a Technical College Regional Library Network

ERIC Educational Resources Information Center

Erb, Rachel A.

2008-01-01

The South Carolina Information and Library Services Consortium (SCILS) began with three public two-year college libraries in 1995. Since then, nine other public two-year college libraries have joined SCILS. In 2004, Sirsi's buyout of Data Research Associates (DRA) in 2001 was the impetus for SCILS to migrate to Sirsi. Migration to a more dynamic…

Typing Postal Cards. Student's Manual and Instructor's Manual.

ERIC Educational Resources Information Center

Snapp, Jane

Supporting performance objective 85 of the V-TECS (Vocational-Technical Education Consortium of States) Secretarial Catalog, both a set of student materials and an instructor's manual on typing postal cards are included in this packet. (The packet is the seventh in a set of fifteen on typewriting--CE 016 920-934.) The student materials include a…

Filing Alphabetically. Basic Rules. Student's Manual and Instructor's Manual.

ERIC Educational Resources Information Center

McLeod, Sadie

Supporting performance objectives 21, 25, and 26 of the V-TECS (Vocational-Technical Education Consortium of States) Secretarial Catalog, both a set of student materials and an instructor's manual on the basic rules of filing alphabetically are included in this packet. (The packet is the first in a set of nine on maintaining files and a…

Training and the Development of Curriculum Standards in On Farm Water Management: Pakistan, 1984-1985.

ERIC Educational Resources Information Center

Bergsma, Harold M.

The document describes the 18-month Phase I of the On Farm Management Project--supported by the World Bank and operated by Colorado State University and the Consortium for International Development--to design more systematic approaches to train people who will work in technical settings related to water management and irrigation channel…

Performance Objectives, Task Analysis, Learning Content, Content Limits, and Domain Referenced Tests for the Agricultural Chemicals Catalog. Final Report.

ERIC Educational Resources Information Center

Hamilton, William; And Others

This document contains Indiana agricultural chemicals curriculum materials based on the Vocational-Technical Education Consortium of States (VTECS) Agricultural Chemicals Catalog. It is intended to improve preparation of high school and adult students for handling and using agricultural chemicals and for jobs as chemical salespersons or chemical…

Building Capability in Vocational Education and Training Providers: The TAFE Cut. Occasional Paper

ERIC Educational Resources Information Center

Guthrie, Hugh; Clayton, Berwyn

2010-01-01

This paper focuses on issues which affect the capability of technical and further education (TAFE) providers to meet their clients' and stakeholders' needs and draws extensively on the reports of the consortium research program which examined ways to help build vocational education and training (VET) provider and workforce capability. The paper…

Outcomes Assessment in Postsecondary Occupational Programs: A Consortial Approach. Project Report.

ERIC Educational Resources Information Center

Winter, Gene M.; Fadale, LaVerna M.

The Two-Year College Development Center, in cooperation with the New York State Education Department and seven community colleges in the Mid-Hudson Region of New York State conducted a 2-year project to determine the outcomes of selected occupational technical programs and feasible ways to measure them. The project operated as a consortium with…

Computing Gross Pay from Punched Time Cards. Student Manual and Instructor's Manual.

ERIC Educational Resources Information Center

McElveen, Peggy C.

Supporting performance objective 30 of the V-TECS (Vocational-Technical Education Consortium of States) Secretarial Catalog, both a set of student materials and an instructor's manual on computing gross pay from punched time cards are included in this packet, which is part of a series. The student materials include a group of time cards,…

Preparing Payroll Register, Employee Earnings' Records, and Paychecks. Student's Manual and Instructor's Manual.

ERIC Educational Resources Information Center

McElveen, Peggy C.

Supporting performance objective 28 of the V-TECS (Vocational-Technical Education Consortium of States) Secretarial Catalog, both a set of student materials and an instructor's manual on preparing a payroll register, employee earnings' records, and paychecks are included in this packet, which is one in a series. The student materials include a…

Coordinating and Performing Activities for Employer. Preparing Expense Reports. Student Manual and Teacher's Manual.

ERIC Educational Resources Information Center

Jones, Maleeta M.

Supporting performance objective 13 of the V-TECS (Vocational-Technical Education Consortium of States) Secretarial Catalog, both a set of student materials and an instructor's manual on preparing employer's business expense statements are included in this packet. (The packet is the fourth in a set of four on coordinating and performing activities…

48 CFR 742.1170-4 - Progress reporting requirements and contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... progress. (b) Because the cognizant technical officer is the individual most familiar with the contractor's performance, the contractor must submit the progress reports directly to the cognizant technical officer. The cognizant technical officer must review the reports and advise the contracting officer, in writing, of any...

Tribal Colleges and Universitie/American Indian Higher Education Consortium Advanced Manufacturing Technical Assistance Project.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Atcitty, Stanley

The National Nuclear Security Agency (NNSA) created a Minority Serving Institution Partnership Plan (MSIPP) to 1) align investments in a university capacity and workforce development with the NNSA mission to develop the needed skills and talent for NNSA’s enduring technical workforce at the laboratories and production plants and 2) to enhance research and education at under-represented colleges and universities. Out of this effort, MSIPP launched a new program in early FY17 focused on Tribal Colleges and Universities (TCUs). The following report summarizes the project focus and status update during this reporting period.

Tribal Colleges and Universitie/American Indian Higher Education Consortium Advanced Manufacturing Technical Assistance Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Atcitty, Stanley

The National Nuclear Security Agency (NNSA) created a Minority Serving Institution Partnership Plan (MSIPP) to 1) align investments in a university capacity and workforce development with the NNSA mission to develop the needed skills and talent for NNSA’s enduring technical workforce at the laboratories and production plants and 2) to enhance research and education at under-represented colleges and universities. Out of this effort, MSIPP launched a new program in early FY17 focused on Tribal Colleges and Universities (TCUs). The following report summarizes the project focus and status update during this reporting period.

USDOT Tier 1 University Transportation Center Program progress performance report #5.

DOT National Transportation Integrated Search

2016-04-29

MarTREC is a USDOT Tier 1 University Transportation Center funded in September 30, 2013 : under MAP-21. Our consortium consists of the University of Arkansas (UARK), Fayetteville, AR; : Jackson State University (JSU), Jackson, MS; Louisiana State Uni...

The biology of Theileria parva and control of East Coast fever - Current status and future trends.

PubMed

Nene, Vishvanath; Kiara, Henry; Lacasta, Anna; Pelle, Roger; Svitek, Nicholas; Steinaa, Lucilla

2016-06-01

Tremendous progress has been made over the last ten years on East Coast fever (ECF) research. Publication of a reference genome sequence of Theileria parva, the causative agent of ECF, has led to a more thorough characterization of the genotypic and antigenic diversity of the pathogen. It also facilitated identification of antigens that are targets of bovine major histocompatibility complex class I restricted cytotoxic T-lymphocytes (CTLs), induced by a live parasite-based infection and treatment method (ITM) vaccine. This has led to improved knowledge of epitope-specific T-cell responses to ITM that most likely contribute to the phenomenon of strain-specific immunity. The Muguga cocktail ITM vaccine, which provides broad-spectrum immunity to ECF is now a registered product in three countries in eastern Africa. Effort is directed at improving and scaling up the production process to make this vaccine more widely available on a commercial basis in the region. Meanwhile, research to develop a subunit vaccine based on parasite neutralizing antibodies and CTLs has been revived through convening of a research consortium to develop proof-of-concept for a next generation vaccine. Many new scientific and technical advances are facilitating this objective. Hence, the next decade promises even more progress toward an improved control of ECF. Copyright © 2016 The Authors. Published by Elsevier GmbH.. All rights reserved.

Education, Technical Progress, and Economic Growth: The Case of Taiwan.

ERIC Educational Resources Information Center

Lin, T.-C.

2003-01-01

Investigates the effect of education and the role of technical progress on economic growth in Taiwan from 1965-2000. Finds that education has a positive and significant effect on growth, but the role of technical progress does not appear to be extraordinarily important. Furthermore, no markedly significant relationships exist between capital and…

A Proposal for the use of the Consortium Method in the Design-build system

NASA Astrophysics Data System (ADS)

Miyatake, Ichiro; Kudo, Masataka; Kawamata, Hiroyuki; Fueta, Toshiharu

In view of the necessity for efficient implementation of public works projects, it is expected to utilize advanced technical skills of private firms, for the purpose of reducing project costs, improving performance and functions of construction objects, and reducing work periods, etc. The design-build system is a method to order design and construction as a single contract, including design of structural forms and main specifications of the construction object. This is a system in which high techniques of private firms can be utilized, as a means to ensure qualities of design and construction, rational design, and efficiency of the project. The objective of this study is to examine the use of a method to form a consortium of civil engineering consultants and construction companies, as it is an issue related to the implementation of the design-build method. Furthermore, by studying various forms of consortiums to be introduced in future, it proposes procedural items required to utilize this method, during the bid and after signing a contract, such as the estimate submission from the civil engineering consultants etc.

Access Skills. Vocational Readiness Skills Inventory for Special Needs Students. (Revised Entry Level Skills Inventory.) Missouri LINC.

ERIC Educational Resources Information Center

Cassity, Sandra; Boyer-Stephens, Arden

This manual is intended to assist special educators and vocational educators in determining the vocational readiness skills of special needs students. The information in this Missouri inventory is based on data provided by the Michigan Occupational Data Analysis System (ODAS) as a part of the Vocational-Technical Education Consortium of States…

National Technical Assistance Consortium for Children and Young Adults Who Are Deaf-Blind. Final Report.

ERIC Educational Resources Information Center

Stremel, Kathleen

This final report discusses the activities and outcomes of a project designed to assist states in improving the quality of existing placements and services for individuals (birth through young adulthood) who are deaf-blind, and to increase the number of children, their families, and their service providers who will benefit from these services. The…

Digital Dilemma: Intellectual Property [and] The ERCIM Technical Reference Digital Library [and] International Information Gateway Collaboration [and] The Standards Fora for Online Education.

ERIC Educational Resources Information Center

Gladney, Henry M.; Andreoni, Antonella; Baldacci, Maria Bruna; Biagioni, Stefania; Carlesi, Carlo; Castelli, Donatella; Pagano, Pasquale; Peters, Carol; Pisani, Serena; Dempsey, Lorcan; Gardner, Tracy; Day, Michael; van der Werf, Titia; Bacsich, Paul; Heath, Andy; Lefrere, Paul; Miller, Paul; Riley, Kevin

1999-01-01

Includes four articles that discuss the impact of the emerging digital information infrastructure on intellectual property; the implementation of a digital library for a European consortium of national research institutions; an international information gateway collaboration; and developing standards for the description and sharing of educational…

A Study of Entry-Level Employment Technological Competencies for the Junior College Graduates Majoring in Electronic Engineering.

ERIC Educational Resources Information Center

Chen, Woei-Kae; Chang, Liang-Te

A study examined the technological competencies of the electronic engineering departments of junior colleges in Taiwan. It used a combination of two methods--a revised DACUM (Developing a Curriculum) process and a revised V-TECS (Vocational-Technical Education Consortium of States) process--to analyze the duty/task profile and task/element list of…

Generic Workplace Skills for Job Application, Employment Retention, and Career Promotion in Today's Economic Environment.

ERIC Educational Resources Information Center

Broadbent, William A.

A study used the Vocational-Technical Education Consortium of States (V-TECS) workplace skills inventory in a validation exercise for use of the inventory in Hawaii. A facilitator reduced the size of the V-TECS instrument. The resulting document was tested using several colleagues of the principal investigator before it was used in the field. The…

Development of a Curriculum to Meet Changing Manpower Needs of the Computer and Business Machine Industries; Interim Developments. Final Report.

ERIC Educational Resources Information Center

Lescarbeau, Roland F.; And Others

This suggested curriculum guide represents the consensus of opinion by the representatives of seven schools comprising the Technical Education Consortium, with advice of industrial experts concerning the essential educational needs of the technicians they would employ. It will serve as a guide to schools planning to institute a program applicable…

Webinar May 17: Fuel Cell Electric Bus Progress Toward Meeting Technical

Science.gov Websites

Targets | News | NREL Webinar May 17: Fuel Cell Electric Bus Progress toward Meeting Technical Targets Webinar May 17: Fuel Cell Electric Bus Progress toward Meeting Technical Targets May 14, 2018 The U.S. Department of Energy's (DOE's) Fuel Cell Technologies Office will present a live webinar titled

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.

PubMed

Thompson, Paul M; Stein, Jason L; Medland, Sarah E; Hibar, Derrek P; Vasquez, Alejandro Arias; Renteria, Miguel E; Toro, Roberto; Jahanshad, Neda; Schumann, Gunter; Franke, Barbara; Wright, Margaret J; Martin, Nicholas G; Agartz, Ingrid; Alda, Martin; Alhusaini, Saud; Almasy, Laura; Almeida, Jorge; Alpert, Kathryn; Andreasen, Nancy C; Andreassen, Ole A; Apostolova, Liana G; Appel, Katja; Armstrong, Nicola J; Aribisala, Benjamin; Bastin, Mark E; Bauer, Michael; Bearden, Carrie E; Bergmann, Orjan; Binder, Elisabeth B; Blangero, John; Bockholt, Henry J; Bøen, Erlend; Bois, Catherine; Boomsma, Dorret I; Booth, Tom; Bowman, Ian J; Bralten, Janita; Brouwer, Rachel M; Brunner, Han G; Brohawn, David G; Buckner, Randy L; Buitelaar, Jan; Bulayeva, Kazima; Bustillo, Juan R; Calhoun, Vince D; Cannon, Dara M; Cantor, Rita M; Carless, Melanie A; Caseras, Xavier; Cavalleri, Gianpiero L; Chakravarty, M Mallar; Chang, Kiki D; Ching, Christopher R K; Christoforou, Andrea; Cichon, Sven; Clark, Vincent P; Conrod, Patricia; Coppola, Giovanni; Crespo-Facorro, Benedicto; Curran, Joanne E; Czisch, Michael; Deary, Ian J; de Geus, Eco J C; den Braber, Anouk; Delvecchio, Giuseppe; Depondt, Chantal; de Haan, Lieuwe; de Zubicaray, Greig I; Dima, Danai; Dimitrova, Rali; Djurovic, Srdjan; Dong, Hongwei; Donohoe, Gary; Duggirala, Ravindranath; Dyer, Thomas D; Ehrlich, Stefan; Ekman, Carl Johan; Elvsåshagen, Torbjørn; Emsell, Louise; Erk, Susanne; Espeseth, Thomas; Fagerness, Jesen; Fears, Scott; Fedko, Iryna; Fernández, Guillén; Fisher, Simon E; Foroud, Tatiana; Fox, Peter T; Francks, Clyde; Frangou, Sophia; Frey, Eva Maria; Frodl, Thomas; Frouin, Vincent; Garavan, Hugh; Giddaluru, Sudheer; Glahn, David C; Godlewska, Beata; Goldstein, Rita Z; Gollub, Randy L; Grabe, Hans J; Grimm, Oliver; Gruber, Oliver; Guadalupe, Tulio; Gur, Raquel E; Gur, Ruben C; Göring, Harald H H; Hagenaars, Saskia; Hajek, Tomas; Hall, Geoffrey B; Hall, Jeremy; Hardy, John; Hartman, Catharina A; Hass, Johanna; Hatton, Sean N; Haukvik, Unn K; Hegenscheid, Katrin; Heinz, Andreas; Hickie, Ian B; Ho, Beng-Choon; Hoehn, David; Hoekstra, Pieter J; Hollinshead, Marisa; Holmes, Avram J; Homuth, Georg; Hoogman, Martine; Hong, L Elliot; Hosten, Norbert; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E; Hwang, Kristy S; Jack, Clifford R; Jenkinson, Mark; Johnston, Caroline; Jönsson, Erik G; Kahn, René S; Kasperaviciute, Dalia; Kelly, Sinead; Kim, Sungeun; Kochunov, Peter; Koenders, Laura; Krämer, Bernd; Kwok, John B J; Lagopoulos, Jim; Laje, Gonzalo; Landen, Mikael; Landman, Bennett A; Lauriello, John; Lawrie, Stephen M; Lee, Phil H; Le Hellard, Stephanie; Lemaître, Herve; Leonardo, Cassandra D; Li, Chiang-Shan; Liberg, Benny; Liewald, David C; Liu, Xinmin; Lopez, Lorna M; Loth, Eva; Lourdusamy, Anbarasu; Luciano, Michelle; Macciardi, Fabio; Machielsen, Marise W J; Macqueen, Glenda M; Malt, Ulrik F; Mandl, René; Manoach, Dara S; Martinot, Jean-Luc; Matarin, Mar; Mather, Karen A; Mattheisen, Manuel; Mattingsdal, Morten; Meyer-Lindenberg, Andreas; McDonald, Colm; McIntosh, Andrew M; McMahon, Francis J; McMahon, Katie L; Meisenzahl, Eva; Melle, Ingrid; Milaneschi, Yuri; Mohnke, Sebastian; Montgomery, Grant W; Morris, Derek W; Moses, Eric K; Mueller, Bryon A; Muñoz Maniega, Susana; Mühleisen, Thomas W; Müller-Myhsok, Bertram; Mwangi, Benson; Nauck, Matthias; Nho, Kwangsik; Nichols, Thomas E; Nilsson, Lars-Göran; Nugent, Allison C; Nyberg, Lars; Olvera, Rene L; Oosterlaan, Jaap; Ophoff, Roel A; Pandolfo, Massimo; Papalampropoulou-Tsiridou, Melina; Papmeyer, Martina; Paus, Tomas; Pausova, Zdenka; Pearlson, Godfrey D; Penninx, Brenda W; Peterson, Charles P; Pfennig, Andrea; Phillips, Mary; Pike, G Bruce; Poline, Jean-Baptiste; Potkin, Steven G; Pütz, Benno; Ramasamy, Adaikalavan; Rasmussen, Jerod; Rietschel, Marcella; Rijpkema, Mark; Risacher, Shannon L; Roffman, Joshua L; Roiz-Santiañez, Roberto; Romanczuk-Seiferth, Nina; Rose, Emma J; Royle, Natalie A; Rujescu, Dan; Ryten, Mina; Sachdev, Perminder S; Salami, Alireza; Satterthwaite, Theodore D; Savitz, Jonathan; Saykin, Andrew J; Scanlon, Cathy; Schmaal, Lianne; Schnack, Hugo G; Schork, Andrew J; Schulz, S Charles; Schür, Remmelt; Seidman, Larry; Shen, Li; Shoemaker, Jody M; Simmons, Andrew; Sisodiya, Sanjay M; Smith, Colin; Smoller, Jordan W; Soares, Jair C; Sponheim, Scott R; Sprooten, Emma; Starr, John M; Steen, Vidar M; Strakowski, Stephen; Strike, Lachlan; Sussmann, Jessika; Sämann, Philipp G; Teumer, Alexander; Toga, Arthur W; Tordesillas-Gutierrez, Diana; Trabzuni, Daniah; Trost, Sarah; Turner, Jessica; Van den Heuvel, Martijn; van der Wee, Nic J; van Eijk, Kristel; van Erp, Theo G M; van Haren, Neeltje E M; van 't Ent, Dennis; van Tol, Marie-Jose; Valdés Hernández, Maria C; Veltman, Dick J; Versace, Amelia; Völzke, Henry; Walker, Robert; Walter, Henrik; Wang, Lei; Wardlaw, Joanna M; Weale, Michael E; Weiner, Michael W; Wen, Wei; Westlye, Lars T; Whalley, Heather C; Whelan, Christopher D; White, Tonya; Winkler, Anderson M; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Zilles, David; Zwiers, Marcel P; Thalamuthu, Anbupalam; Schofield, Peter R; Freimer, Nelson B; Lawrence, Natalia S; Drevets, Wayne

2014-06-01

The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way.

Technical Summary of the Half-Degree Imager (HDI)

NASA Astrophysics Data System (ADS)

Richmond, Michael W.

2017-01-01

The Half-Degree Imager (HDI) was first attached to the WIYN 0.9-m Telescope in October, 2013. In the three years since then, it has served a large community of astronomers throughout the WIYN 0.9-m consortium. The large field of view and relatively short readout time, combined with a large selection of broad-band and narrow-band filters, make HDI a powerful tool for large-area surveys. I will provide a summary of the technical features of this CCD camera and its operations, and present statistics on its use -- showing the fraction of time lost due to bad weather and technical problems. I will reserve time to answer questions from the audience, including those who may be interested in using HDI for their own projects.

25 CFR 30.111 - When should the tribal governing body or school board request technical assistance?

Code of Federal Regulations, 2011 CFR

2011-04-01

... request technical assistance? 30.111 Section 30.111 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.111 When should the tribal governing body or school board request technical assistance? In order to...

Northeast Artificial Intelligence Consortium (NAIC) Review of Technical Tasks. Volume 2, Part 1.

DTIC Science & Technology

1987-07-01

34- . 6.2 Transformation Invariant Attributes for S Digitized Object Outlines ................................. 469 6.3 Design of an Inference Engine for an...Attributes for Digital Object Outlines ...................................... 597 7 SPEECH UNDERSTANDING RESEARCH ( Rochester Institute of Technology...versatile maintenance expert system ES) for trouble-shooting--’ digital circuits. +" Some diagnosis systems, such as MYCLN [19] for medical diagnosis and CRIB

Parent Perspectives on Communication, Behavioral, and Instructional Strategies for Children and Youth Who Are Deaf-Blind.

ERIC Educational Resources Information Center

National Technical Assistance Consortium for Children and Young Adults Who Are Deaf-Blind, Monmouth, OR.

From July 30-August 1, 1998, eighty parents and family members from across the country attended a national workshop held in St. Louis, Missouri sponsored by the National Technical Assistance Consortium for Children and Young Adults who are Deaf-Blind and the National Family Association for Deaf-Blind. The workshop, entitled "Going for the Best:…

Toward a "Common Definition of English Learner": A Brief Defining Policy and Technical Issues and Opportunities for State Assessment Consortia

ERIC Educational Resources Information Center

Linquanti, Robert; Cook, H. Gary

2013-01-01

The U.S. Department of Education (USED) requires states participating in either of the two Race to the Top assessment consortia (Smarter Balanced Assessment Consortium and Partnership for Assessment of Readiness for College and Careers [PARCC]), as well as those participating in either of the two Enhanced Assessment Grant (EAG) English language…

Unvented Attic Increases Energy Efficiency and Reduces Duct Losses - Sun Lake at Banning, California

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, R.; Wells, N.

2001-09-05

New houses in the Sun Lakes at Banning subdivision are designed by Pulte Homes with technical support from the Building Science Consortium as part of the U.S. Department of Energy's Building America Program. These homes save their homeowners money by applying the principles of ''whole-building'' design, which considers the house as a complete system instead of separate components.

ACT-CCREC Core Research Program: Study Questions and Design. ACT Working Paper Series. WP-2015-01

ERIC Educational Resources Information Center

Cruce, Ty M.

2015-01-01

This report provides a non-technical overview of the guiding research questions and research design for the ACT-led core research program conducted on behalf of the GEAR UP College and Career Readiness Evaluation Consortium (CCREC). The core research program is a longitudinal study of the effectiveness of 14 GEAR UP state grants on the academic…

Translational Biomarkers of Neurotoxicity: An ILSI_HESI Consortium Perspective on Identifying and Accessing Biomarkers

EPA Science Inventory

Environmental toxicants such as mercury, manganese, pesticides and others; contaminants in designer drugs of abuse such as MPTP; and a vast and growing inventory of industrial chemicals have been linked to neurological damage and a significant number of progressive neurological d...

Substantially enhanced degradation of hexachlorocyclohexane isomers by a microbial consortium on acclimation.

PubMed

Elcey, C Daniel; Kunhi, A A Mohammad

2010-01-27

Widespread contamination of the environment, globally, has been caused by extensive and indiscriminate use of hexachlorocyclohexane (HCH) as an insecticide since the 1940s, threatening the biota including humans, and there is an urgent need to eliminate it, preferably through bioremediation technologies. A gamma-HCH-degrading microbial consortium was isolated by enrichment of a soil sample from a sugar cane field having a long history of technical grade HCH application. On acclimation the degrading ability improved substantially. The consortium, which took 10 days to degrade 25 microg mL(-1) of gamma-HCH, initially could mineralize even 300 microg mL(-1) of the substrate within 108 h on acclimation. With 300 microg mL(-1) substrate, the rate of degradation, as calculated for the early exponential phase, was 216 microg mL(-1) day(-1), the highest reported so far. An amount of 400 microg mL(-1) of gamma-HCH, however, was mineralized partially with only 78% Cl(-) release. No apparent accumulation of intermediary metabolites was observed up to 300 microg mL(-1) substrate, indicating a fast rate of mineralization. Aeration, mesophilic temperatures (20-35 degrees C), and near neutral pH (6.0-8.0) were favorable conditions for degradation. The presence of glucose at 1000 microg mL(-1) retarded the degradation, whereas cellulose and sawdust at 1600 microg mL(-1) and glucose at 100 microg mL(-1) did not show any marked effect. The consortium also mineralized alpha-, beta-, and delta-HCH efficiently. The consortium consisted of nine bacterial strains and a fungal strain, and individually they were able to degrade 10 microg mL(-1) of gamma-HCH. This mixed culture holds high potential for deployment in bioremediation of HCH-contaminated soils, waste dumpsites, and water bodies.

25 CFR 30.110 - What is the process for requesting technical assistance to develop an alternative definition of AYP?

Code of Federal Regulations, 2011 CFR

2011-04-01

..., DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.110 What is the process for requesting technical assistance to develop an alternative... 25 Indians 1 2011-04-01 2011-04-01 false What is the process for requesting technical assistance...

25 CFR 30.110 - What is the process for requesting technical assistance to develop an alternative definition of AYP?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What is the process for requesting technical assistance..., DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.110 What is the process for requesting technical assistance to develop an alternative...

Ophthalmic epidemiology in Europe: the "European Eye Epidemiology" (E3) consortium.

PubMed

Delcourt, Cécile; Korobelnik, Jean-François; Buitendijk, Gabriëlle H S; Foster, Paul J; Hammond, Christopher J; Piermarocchi, Stefano; Peto, Tunde; Jansonius, Nomdo; Mirshahi, Alireza; Hogg, Ruth E; Bretillon, Lionel; Topouzis, Fotis; Deak, Gabor; Grauslund, Jakob; Broe, Rebecca; Souied, Eric H; Creuzot-Garcher, Catherine; Sahel, José; Daien, Vincent; Lehtimäki, Terho; Hense, Hans-Werner; Prokofyeva, Elena; Oexle, Konrad; Rahi, Jugnoo S; Cumberland, Phillippa M; Schmitz-Valckenberg, Steffen; Fauser, Sascha; Bertelsen, Geir; Hoyng, Carel; Bergen, Arthur; Silva, Rufino; Wolf, Sebastian; Lotery, Andrew; Chakravarthy, Usha; Fletcher, Astrid; Klaver, Caroline C W

2016-02-01

The European Eye Epidemiology (E3) consortium is a recently formed consortium of 29 groups from 12 European countries. It already comprises 21 population-based studies and 20 other studies (case-control, cases only, randomized trials), providing ophthalmological data on approximately 170,000 European participants. The aim of the consortium is to promote and sustain collaboration and sharing of data and knowledge in the field of ophthalmic epidemiology in Europe, with particular focus on the harmonization of methods for future research, estimation and projection of frequency and impact of visual outcomes in European populations (including temporal trends and European subregions), identification of risk factors and pathways for eye diseases (lifestyle, vascular and metabolic factors, genetics, epigenetics and biomarkers) and development and validation of prediction models for eye diseases. Coordinating these existing data will allow a detailed study of the risk factors and consequences of eye diseases and visual impairment, including study of international geographical variation which is not possible in individual studies. It is expected that collaborative work on these existing data will provide additional knowledge, despite the fact that the risk factors and the methods for collecting them differ somewhat among the participating studies. Most studies also include biobanks of various biological samples, which will enable identification of biomarkers to detect and predict occurrence and progression of eye diseases. This article outlines the rationale of the consortium, its design and presents a summary of the methodology.

U. S. Veterinary Immune Reagents Network: Progress with poultry immune reagents development

USDA-ARS?s Scientific Manuscript database

A major obstacle to advances in veterinary immunology and disease research is the lack of sufficient immunological reagents specific for veterinary animal species. In 2006, U. S. Veterinary Immune Reagent Network (VIRN) Consortium (www.vetimm.org) was developed to develop immune reagents against ma...

LARC2: Integrated Children's Services and the CAF Process

ERIC Educational Resources Information Center

Easton, Claire; Morris, Marian; Gee, Geoff

2010-01-01

The local authority research consortium (LARC), established in 2007, supports children's service authorities in using and conducting research to evaluate progress, to inform practice, share findings and make recommendations locally and nationally. This summary reports the collective findings of the 24 authorities involved in the LARC2 project…

CHARACTERIZATION OF A METHANE-UTILIZING BACTERIUM FROM A BACTERIAL CONSORTIUM THAT RAPIDLY DEGRADES TRICHLOROETHYLENE AND CHLOROFORM. (R825689C041)

EPA Science Inventory

The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

14 CFR 1274.701 - Suspension or termination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Agreement if the recipient is not making anticipated technical progress, if the recipient materially changes...) Similarly, the recipient may terminate the agreement if, for example, technical progress is not being made, if the commercial recipient shifts its technical emphasis, or if other technological advances have...

14 CFR 1274.701 - Suspension or termination.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Agreement if the recipient is not making anticipated technical progress, if the recipient materially changes...) Similarly, the recipient may terminate the agreement if, for example, technical progress is not being made, if the commercial recipient shifts its technical emphasis, or if other technological advances have...

ESPRESSO: projecting a rocky exoplanet hunter for the VLT

NASA Astrophysics Data System (ADS)

Mégevand, Denis; Herreros, José-Miguel; Zerbi, Filippo; Cabral, Alexandre; Di Marcantonio, Paolo; Lovis, Christophe; Pepe, Francesco; Cristiani, Stefano; Rebolo, Rafael; Santos, Nuno C.

2010-07-01

ESPRESSO is a high-resolution, highly stable spectrograph for the VLT. It will inherit and enhance most capabilities from HARPS and UVES, combining both stability and efficiency. The main science driver will be the detection and characterization of Earth-like planets, but many additional science cases will benefit from its highly stable spectroscopic observations. The facility will be installed at the combined Coudé focus of the VLT and may be linked with any of the four UT telescopes, enabling thus a great flexibility for the efficient use of telescope time. This particularity makes the interface with the VLT more complex than for an instrument fed by a single telescope. It impacts on the complexity of the relationship between the consortium providing the instrument and ESO, the customer. The targeted high RV accuracy requires very high performances in stability and resolution, which in turn require adequate technical solutions at several levels. This paper describes the instrument system and subsystems, enlightening the most valuable differences between ESPRESSO and it's predecessors, the details of the project, entering now the design phases, the ESPRESSO consortium, composed of Italian, Portuguese, Spanish and Swiss institutes, and the relationship between the consortium and ESO.

A Project to Computerize Performance Objectives and Criterion-Referenced Measures in Occupational Education for Research and Determination of Applicability to Handicapped Learners. Final Report.

ERIC Educational Resources Information Center

Lee, Connie W.; Hinson, Tony M.

This publication is the final report of a 21-month project designed to (1) expand and refine the computer capabilities of the Vocational-Technical Education Consortium of States (V-TECS) to ensure rapid data access for generating routine and special occupational data-based reports; (2) develop and implement a computer storage and retrieval system…

Main High-Resolution Near-IR Spectrometer for the VLT

NASA Astrophysics Data System (ADS)

Piskunov, N.

2017-06-01

We present the ongoing CRISES+ project on the development of a cross-dispersed high resolution near-infrared spectrometer for the ESO Very Large Telescope. The presentation highlights the relation between science objectives, technical solutions, and the structure of the project. We also share some of the insights on the implementation and management of the project that are crucial for keeping the tight time-line through efficient interaction between consortium members.

Clinical Epidemiology (CE) and Evidence-Based Medicine (EBM) in the Asia Pacific region (Round Table Forum).

PubMed

Su, Tin Tin; Bulgiba, Awang M; Sampatanukul, Pichet; Sastroasmoro, Sudigdo; Chang, Peter; Tharyan, Prathap; Lin, Vivian; Wong, Yut Lin

2013-01-01

Clinical Epidemiology (CE) and Evidence-Based Medicine (EBM) have become increasingly important in an era of rising costs, patient safety concerns and evidence-based health care. CE and EBM research in the Asia Pacific region have grown significantly. However, there are three main challenges such as linking evidence to practice and policy; developing a strong collaborative network; and a need for resources and technical expertise to produce evidence. The Cochrane Collaboration is a possible solution to resolve above challenges identified, particularly the challenge of transforming evidence to practice. In addition, training can be carried out to enhance technical expertise in the region and there is also the promising potential that collaborations could extend beyond systematic reviews. To improve the adoption of evidence-based health policy, selection of the best evidence for the right audience and focusing on the relevant issues through appropriate methodology are essential. Information on effectiveness and cost effectiveness needs to be highlighted for policy makers. The way forward to strengthen research and capacity building is to establish the Asia Pacific Consortium for CE and EBM. The consortium would help to create mutually rewarding scientific research and collaborations that will augur well for advances in CE and EBM. Copyright © 2013 Elsevier Inc. All rights reserved.

Progress in Scientific and Technical Communications, 1968 Annual Report.

ERIC Educational Resources Information Center

Federal Council for Science and Technology, Washington, DC. Committee on Scientific and Technical Information.

This sixth annual report describes progress achieved by the Federal Government in improving the communication of scientific and technical information to support and enhance national science and technology. Included in the report are details regarding the scientific and technical activities of individual Federal Agencies, such as the Atomic Energy…

Conceptualizing a Genomics Software Institute (GSI)

PubMed Central

Gilbert, Jack A.; Catlett, Charlie; Desai, Narayan; Knight, Rob; White, Owen; Robbins, Robert; Sankaran, Rajesh; Sansone, Susanna-Assunta; Field, Dawn; Meyer, Folker

2012-01-01

Microbial ecology has been enhanced greatly by the ongoing ‘omics revolution, bringing half the world's biomass and most of its biodiversity into analytical view for the first time; indeed, it feels almost like the invention of the microscope and the discovery of the new world at the same time. With major microbial ecology research efforts accumulating prodigious quantities of sequence, protein, and metabolite data, we are now poised to address environmental microbial research at macro scales, and to begin to characterize and understand the dimensions of microbial biodiversity on the planet. What is currently impeding progress is the need for a framework within which the research community can develop, exchange and discuss predictive ecosystem models that describe the biodiversity and functional interactions. Such a framework must encompass data and metadata transparency and interoperation; data and results validation, curation, and search; application programming interfaces for modeling and analysis tools; and human and technical processes and services necessary to ensure broad adoption. Here we discuss the need for focused community interaction to augment and deepen established community efforts, beginning with the Genomic Standards Consortium (GSC), to create a science-driven strategic plan for a Genomic Software Institute (GSI). PMID:22675605

48 CFR 2452.242-71 - Contract management system.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., concise summary of technical progress made and the costs incurred for each task during the reporting... technical progress made for each task during the reporting period; and (B) Identifies problems, or potential... and progress reporting as described herein. (b) The contract management system shall consist of two...

The Relationship between Language Literacy and ELL Student Academic Performance in Mathematics

ERIC Educational Resources Information Center

Lawon, Molly A.

2017-01-01

This quantitative study used regression analysis to investigate the correlation of limited language proficiency and the performance of English Language Learner (ELL) students on two commonly used math assessments, namely the Smarter Balanced Assessment Consortium (SBAC) and the Measures of Academic Progress (MAP). Scores were analyzed for eighth…

Rethinking edTPA: The Use of InTASC Principles and Standards

ERIC Educational Resources Information Center

Kuo, Nai-Cheng

2018-01-01

The Interstate Teacher Assessment and Support Consortium (InTASC) Model Core Teaching Standards and Learning Progressions for Teachers 1.0, developed by the Council of Chief State School Officers (CCSSO, 2013) in the United States, provide a set of expectations for essential knowledge, critical disposition, and performance needed for high-quality…

Achieving Sustainability through Targeted Curriculum Change. Strategies for Transformative Change

ERIC Educational Resources Information Center

Audant, B.; Kirby, C.

2016-01-01

Integrated academic skills instruction was one of the core elements of the CareerPATH consortium that provided math, reading, writing, and English language skills instruction "contextualized" to occupational training. Its goal was to engage adult learners and accelerate their progress in college and careers. The focus of this brief is…

Meeting report of the International Consortium of Stem Cell Networks' Workshop Towards Clinical Trials Using Stem Cells for Amyotrophic Lateral Sclerosis/Motor Neuron Disease.

PubMed

Chaddah, Maya R; Dickie, Brian G; Lyall, Drew; Marshall, Caroline J; Sykes, J Ben; Bruijn, Lucie I

2011-09-01

The International Consortium of Stem Cell Networks' (ICSCN) Workshop Towards Clinical Trials Using Stem Cells for Amyotrophic Lateral Sclerosis (ALS)/Motor Neuron Disease (MND) was held on 24-25 January 2011. Twenty scientific talks addressed aspects of cell derivation and characterization; preclinical research and phased clinical trials involving stem cells; latest developments in induced pluripotent (iPS) cell technology; industry involvement and investment. Three moderated panel discussions focused on unregulated ALS/MND treatments, and the state of the art and barriers to future progress in using stem cells for ALS/MND. This review highlights the major insights that emanated from the workshop around the lessons learned and barriers to progress for using stem cells for understanding disease mechanism, drug discovery, and as therapy for ALS/MND. The full meeting report is only available in the online version of the journal. Please find this material with the following direct link to the article: http://www.informahealthcare.com/als/doi/10.3109/17482968.2011.590992 .

Use of common analgesic medications and ovarian cancer survival: results from a pooled analysis in the Ovarian Cancer Association Consortium.

PubMed

Dixon, Suzanne C; Nagle, Christina M; Wentzensen, Nicolas; Trabert, Britton; Beeghly-Fadiel, Alicia; Schildkraut, Joellen M; Moysich, Kirsten B; deFazio, Anna; Risch, Harvey A; Rossing, Mary Anne; Doherty, Jennifer A; Wicklund, Kristine G; Goodman, Marc T; Modugno, Francesmary; Ness, Roberta B; Edwards, Robert P; Jensen, Allan; Kjær, Susanne K; Høgdall, Estrid; Berchuck, Andrew; Cramer, Daniel W; Terry, Kathryn L; Poole, Elizabeth M; Bandera, Elisa V; Paddock, Lisa E; Anton-Culver, Hoda; Ziogas, Argyrios; Menon, Usha; Gayther, Simon A; Ramus, Susan J; Gentry-Maharaj, Aleksandra; Pearce, Celeste Leigh; Wu, Anna H; Pike, Malcolm C; Webb, Penelope M

2017-04-25

Nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with improved survival in some cancers, but evidence for ovarian cancer is limited. Pooling individual-level data from 12 Ovarian Cancer Association Consortium studies, we evaluated the association between self-reported, pre-diagnosis use of common analgesics and overall/progression-free/disease-specific survival among 7694 women with invasive epithelial ovarian cancer (4273 deaths). Regular analgesic use (at least once per week) was not associated with overall survival (pooled hazard ratios, pHRs (95% confidence intervals): aspirin 0.96 (0.88-1.04); non-aspirin NSAIDs 0.97 (0.89-1.05); acetaminophen 1.01 (0.93-1.10)), nor with progression-free/disease-specific survival. There was however a survival advantage for users of any NSAIDs in studies clearly defining non-use as less than once per week (pHR=0.89 (0.82-0.98)). Although this study did not show a clear association between analgesic use and ovarian cancer survival, further investigation with clearer definitions of use and information about post-diagnosis use is warranted.

ANNUAL REPORT, JULY 1, 1957

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1958-10-31

The progress and trends of research are presented along with a description of operational, service, end administrative activities. Some scientific and technical details are given on research programs in the physical sciences, life sciences, and engineering, however, more complete technical information is available in quarterly progress reports, BNL technical reports, and scientific and technical periodicals. A bibliography of these publications is appended. (For preceding period see BNL-426.) (D.E.B.)

Chile's National Center for Health Information Systems: A Public-Private Partnership to Foster Health Care Information Interoperability.

PubMed

Capurro, Daniel; Echeverry, Aisen; Figueroa, Rosa; Guiñez, Sergio; Taramasco, Carla; Galindo, César; Avendaño, Angélica; García, Alejandra; Härtel, Steffen

2017-01-01

Despite the continuous technical advancements around health information standards, a critical component to their widespread adoption involves political agreement between a diverse set of stakeholders. Countries that have addressed this issue have used diverse strategies. In this vision paper we present the path that Chile is taking to establish a national program to implement health information standards and achieve interoperability. The Chilean government established an inter-agency program to define the current interoperability situation, existing gaps, barriers, and facilitators for interoperable health information systems. As an answer to the identified issues, the government decided to fund a consortium of Chilean universities to create the National Center for Health Information Systems. This consortium should encourage the interaction between all health care stakeholders, both public and private, to advance the selection of national standards and define certification procedures for software and human resources in health information technologies.

Proceedings -- US Russian workshop on fuel cell technologies (in English;Russian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, B.; Sylwester, A.

1996-04-01

On September 26--28, 1995, Sandia National Laboratories sponsored the first Joint US/Russian Workshop on Fuel Cell Technology at the Marriott Hotel in Albuquerque, New Mexico. This workshop brought together the US and Russian fuel cell communities as represented by users, producers, R and D establishments and government agencies. Customer needs and potential markets in both countries were discussed to establish a customer focus for the workshop. Parallel technical sessions defined research needs and opportunities for collaboration to advance fuel cell technology. A desired outcome of the workshop was the formation of a Russian/American Fuel Cell Consortium to advance fuel cellmore » technology for application in emerging markets in both countries. This consortium is envisioned to involve industry and national labs in both countries. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.« less

The power of collaboration: using internet-based tools to facilitate networking and benchmarking within a consortium of academic health centers.

PubMed

Korner, Eli J; Oinonen, Michael J; Browne, Robert C

2003-02-01

The University HealthSystem Consortium (UHC) represents a strategic alliance of 169 academic health centers and associated institutions engaged in knowledge sharing and idea-generation. The use of the Internet as a tool in the delivery of UHC's products and services has increased dramatically over the past year and will continue to increase during the foreseeable future. This paper examines the current state of UHC-member institution driven tools and services that utilize the Web as a fundamental component in their delivery. The evolution of knowledge management at UHC, its management information and reporting tools, and expansion of e-commerce provide real world examples of Internet use in health care delivery and management. Health care workers are using these Web-based tools to help manage rising costs and optimize patient outcomes. Policy, technical, and organizational issues must be resolved to facilitate rapid adoption of Internet applications.

Characterization of the biodegradation, bioremediation and detoxification capacity of a bacterial consortium able to degrade the fungicide thiabendazole.

PubMed

Perruchon, Chiara; Pantoleon, Anastasios; Veroutis, Dimitrios; Gallego-Blanco, Sara; Martin-Laurent, F; Liadaki, Kalliopi; Karpouzas, Dimitrios G

2017-12-01

Thiabendazole (TBZ) is a persistent fungicide used in the post-harvest treatment of fruits. Its application results in the production of contaminated effluents which should be treated before their environmental discharge. In the absence of efficient treatment methods in place, biological systems based on microbial inocula with specialized degrading capacities against TBZ could be a feasible treatment approach. Only recently the first bacterial consortium able to rapidly transform TBZ was isolated. This study aimed to characterize its biodegradation, bioremediation and detoxification potential. The capacity of the consortium to mineralize 14 C-benzyl-ring labelled TBZ was initially assessed. Subsequent tests evaluated its degradation capacity under various conditions (range of pH, temperatures and TBZ concentration levels) and relevant practical scenarios (simultaneous presence of other postharvest compounds) and its bioaugmentation potential in soils contaminated with increasing TBZ levels. Finally cytotoxicity assays explored its detoxification potential. The consortium effectively mineralized the benzoyl ring of the benzimidazole moiety of TBZ and degraded spillage level concentrations of the fungicide in aqueous cultures (750 mg L -1 ) and in soil (500 mg kg -1 ). It maintained its high degradation capacity in a wide range of pH (4.5-7.5) and temperatures (15-37 °C) and in the presence of other pesticides (ortho-phenylphenol and diphenylamine). Toxicity assays using the human liver cancer cell line HepG2 showed a progressive decrease in cytotoxicity, concomitantly with the biodegradation of TBZ, pointing to a detoxification process. Overall, the bacterial consortium showed high potential for future implementation in bioremediation and biodepuration applications.

Special issue on the "Consortium for Advanced Simulation of Light Water Reactors Research and Development Progress"

NASA Astrophysics Data System (ADS)

Turinsky, Paul J.; Martin, William R.

2017-04-01

In this special issue of the Journal of Computational Physics, the research and development completed at the time of manuscript submission by the Consortium for Advanced Simulation of Light Water Reactors (CASL) is presented. CASL is the first of several Energy Innovation Hubs that have been created by the Department of Energy. The Hubs are modeled after the strong scientific management characteristics of the Manhattan Project and AT&T Bell Laboratories, and function as integrated research centers that combine basic and applied research with engineering to accelerate scientific discovery that addresses critical energy issues. Lifetime of a Hub is expected to be five or ten years depending upon performance, with CASL being granted a ten year lifetime.

20 CFR 411.180 - What is timely progress toward self-supporting employment?

Code of Federal Regulations, 2010 CFR

2010-04-01

... certificate or vocational or technical training that will enhance your ability to return to work. In addition...-secondary education requirement or vocational or technical training requirement in the applicable progress... this 12-month period; or (iv) You must have been enrolled in a vocational or technical training program...

Uncovering and Managing the Impact of Methodological Choices for the Computational Construction of Socio-Technical Networks from Texts

DTIC Science & Technology

2012-09-01

supported by the National Science Foundation (NSF) IGERT 9972762, the Army Research Institute (ARI) W91WAW07C0063, the Army Research Laboratory (ARL/CTA...prediction models in AutoMap .................................................. 144   Figure 13: Decision Tree for prediction model selection in...generated for nationally funded initiatives and made available through the Linguistic Data Consortium (LDC). An overview of these datasets is provided in

Consolidated Bio-Processing of Cellulosic Biomass for Efficient Biofuel Production Using Yeast Consortium

NASA Astrophysics Data System (ADS)

Goyal, Garima

Fossil fuels have been the major source for liquid transportation fuels for ages. However, decline in oil reserves and environmental concerns have raised a lot of interest in alternative and renewable energy sources. One promising alternative is the conversion of plant biomass into ethanol. The primary biomass feed stocks currently being used for the ethanol industry have been food based biomass (corn and sugar cane). However, interest has recently shifted to replace these traditional feed-stocks with more abundant, non-food based cellulosic biomass such as agriculture wastes (corn stover) or crops (switch grass). The use of cellulosic biomass as feed stock for the production of ethanol via bio-chemical routes presents many technical challenges not faced with the use of corn or sugar-cane as feed-stock. Recently, a new process called consolidated Bio-processing (CBP) has been proposed. This process combines simultaneous saccharification of lignocellulose with fermentation of the resulting sugars into a single process step mediated by a single microorganism or microbial consortium. Although there is no natural microorganism that possesses all properties of lignocellulose utilization and ethanol production desired for CBP, some bacteria and fungi exhibit some of the essential traits. The yeast Saccharomyces cerevisiae is the most attractive host organism for the usage of this strategy due to its high ethanol productivity at close to theoretical yields (0.51g ethanol/g glucose consumed), high osmo- and ethanol- tolerance, natural robustness in industrial processes, and ease of genetic manipulation. Introduction of the cellulosome, found naturally in microorganisms, has shown new directions to deal with recalcitrant biomass. In this case enzymes work in synergy in order to hydrolyze biomass more effectively than in case of free enzymes. A microbial consortium has been successfully developed, which ensures the functional assembly of minicellulosome on the yeast surface composed of four yeast populations. These yeast populations include: one displaying scaffoldin on its surface and three populations secreting three different cellulases in the medium to hydrolyze the cellulose. The modular nature of the consortium system allows for the fine-tuning of each population by changing their initial inoculum ratio, thereby optimizing the cellulose hydrolysis and hence ethanol production. When comparing the optimized consortium with equal ratio consortium, the optimized one produced almost double the amount of ethanol (1.87 g/l) with a yield of 0.475 g ethanol/g cellulose. To further evaluate the feasibility of using consortium for CBP, it was grown at very low optical density (OD) under anaerobic conditions. Under stressful conditions like low OD and no oxygen, the consortium system was proficient in assembling the cellulosome on its surface and growing on the PAS-avicel as sole carbon source and concomitantly producing ethanol with a yield of 87% of the theoretical value. For the dynamic study of yeast consortium system, quantitative real time PCR was used to enumerate the individual yeast population in the mixed culture. At the end of the cultivation, ratios of each population in this consortium maintained similar number as the initial inoculums ratios, which further confirms the consortium system is suitable for the application of CBP.

System engineering and management in a large and diverse multinational consortium

NASA Astrophysics Data System (ADS)

Wright, David; O'Sullivan, Brian; Thatcher, John; Renouf, Ian; Wright, Gillian; Wells, Martyn; Glasse, Alistair; Grozinger, Ulrich; Sykes, Jon; Smith, Dave; Eccleston, Paul; Shaughnessy, Bryan

2008-07-01

This paper elaborates the system engineering methods that are being successfully employed within the European Consortium (EC) to deliver the Optical System of the Mid Infa-Red Instrument (MIRI) to the James Webb Space Telescope (JWST). The EC is a Consortium of 21 institutes located in 10 European countries and, at instrument level, it works in a 50/50 partnership with JPL who are providing the instrument cooler, software and detector systems. The paper will describe how the system engineering approach has been based upon proven principles used in the space industry but applied in a tailored way that best accommodates the differences in international practices and standards with a primary aim of ensuring a cost-effective solution which supports all science requirements for the mission. The paper will recall how the system engineering has been managed from the definition of the system requirements in early phase B, through the successful Critical Design Review at the end of phase C and up to the test and flight build activities that are presently in progress. Communication and coordination approaches will also be discussed.

Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.

PubMed

Wang, Jun; Kurilshikov, Alexander; Radjabzadeh, Djawad; Turpin, Williams; Croitoru, Kenneth; Bonder, Marc Jan; Jackson, Matthew A; Medina-Gomez, Carolina; Frost, Fabian; Homuth, Georg; Rühlemann, Malte; Hughes, David; Kim, Han-Na; Spector, Tim D; Bell, Jordana T; Steves, Claire J; Timpson, Nicolas; Franke, Andre; Wijmenga, Cisca; Meyer, Katie; Kacprowski, Tim; Franke, Lude; Paterson, Andrew D; Raes, Jeroen; Kraaij, Robert; Zhernakova, Alexandra

2018-06-08

In recent years, human microbiota, especially gut microbiota, have emerged as an important yet complex trait influencing human metabolism, immunology, and diseases. Many studies are investigating the forces underlying the observed variation, including the human genetic variants that shape human microbiota. Several preliminary genome-wide association studies (GWAS) have been completed, but more are necessary to achieve a fuller picture. Here, we announce the MiBioGen consortium initiative, which has assembled 18 population-level cohorts and some 19,000 participants. Its aim is to generate new knowledge for the rapidly developing field of microbiota research. Each cohort has surveyed the gut microbiome via 16S rRNA sequencing and genotyped their participants with full-genome SNP arrays. We have standardized the analytical pipelines for both the microbiota phenotypes and genotypes, and all the data have been processed using identical approaches. Our analysis of microbiome composition shows that we can reduce the potential artifacts introduced by technical differences in generating microbiota data. We are now in the process of benchmarking the association tests and performing meta-analyses of genome-wide associations. All pipeline and summary statistics results will be shared using public data repositories. We present the largest consortium to date devoted to microbiota-GWAS. We have adapted our analytical pipelines to suit multi-cohort analyses and expect to gain insight into host-microbiota cross-talk at the genome-wide level. And, as an open consortium, we invite more cohorts to join us (by contacting one of the corresponding authors) and to follow the analytical pipeline we have developed.

Latest Developments of the Isprs Student Consortium

NASA Astrophysics Data System (ADS)

Detchev, I.; Kanjir, U.; Reyes, S. R.; Miyazaki, H.; Aktas, A. F.

2016-06-01

The International Society for Photogrammetry and Remote Sensing (ISPRS) Student Consortium (SC) is a network for young professionals studying or working within the fields of photogrammetry, remote sensing, Geographical Information Systems (GIS), and other related geo-spatial sciences. The main goal of the network is to provide means for information exchange for its young members and thus help promote and integrate youth into the ISPRS. Over the past four years the Student Consortium has successfully continued to fulfil its mission in both formal and informal ways. The formal means of communication of the SC are its website, newsletter, e-mail announcements and summer schools, while its informal ones are multiple social media outlets and various social activities during student related events. The newsletter is published every three to four months and provides both technical and experiential content relevant for the young people in the ISPRS. The SC has been in charge or at least has helped with organizing one or more summer schools every year. The organization's e-mail list has over 1,100 subscribers, its website hosts over 1,300 members from 100 countries across the entire globe, and its public Facebook group currently has over 4,500 joined visitors, who connect among one another and share information relevant for their professional careers. These numbers show that the Student Consortium has grown into a significant online-united community. The paper will present the organization's on-going and past activities for the last four years, its current priorities and a strategic plan and aspirations for the future four-year period.

Discrete return lidar in natural resources: Recommendations for project planning, data processing, and deliverables

Treesearch

Jeffrey S. Evans; Andrew T. Hudak; Russ Faux; Alistair M. S. Smith

2009-01-01

Recent years have seen the progression of light detection and ranging (lidar) from the realm of research to operational use in natural resource management. Numerous government agencies, private industries, and public/private stakeholder consortiums are planning or have recently acquired large-scale acquisitions, and a national U.S. lidar acquisition is likely before...

Evaporation by mechanical vapor recompression. Technical progress report, September 1-December 31, 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Iverson, C.H.; Coury, G.E.

1979-01-01

Progress to date in the development of a study of the application of the technologies of mechanical vapor recompression and falling film evaporators as applied to the beet sugar industry is reported. Progress is reported in the following areas: technical literature search and plant visitations of existing applications of VR/FFE.

Defining a Technical Basis for Comparing and Contrasting Emerging Dynamic Discovery Protocols

DTIC Science & Technology

2001-05-02

UPnP, SLP, Bluetooth , and HAVi • Projected specific UML models for Jini, UPnP, and SLP • Completed a Rapide Model of Jini structure, function, and...narrow application focus but targeting a different application domain. (e.g., HAVi, Salutation Consortium, and Bluetooth Service Discovery) • Sun has...Our General Approach? 1/31/2002 7 Particulars of Our Approach Define a Generic UML Model that Encompasses Jini, UPnP, SLP, HAVi, and Bluetooth

25 CFR 30.109 - Will the Secretary provide assistance in developing an alternative AYP definition?

Code of Federal Regulations, 2011 CFR

2011-04-01

... EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.109 Will the... Bureau, shall provide technical assistance either directly or through contract to the tribal governing...

25 CFR 30.109 - Will the Secretary provide assistance in developing an alternative AYP definition?

Code of Federal Regulations, 2010 CFR

2010-04-01

... EDUCATION ADEQUATE YEARLY PROGRESS Defining Adequate Yearly Progress Technical Assistance § 30.109 Will the... Bureau, shall provide technical assistance either directly or through contract to the tribal governing...

Sharing perspectives and experiences of doctoral fellows in the first cohort of Consortium for Advanced Research Training in Africa: 2011-2014.

PubMed

Adedokun, Babatunde; Nyasulu, Peter; Maseko, Fresier; Adedini, Sunday; Akinyemi, Joshua; Afolabi, Sulaimon; de Wet, Nicole; Sulaimon, Adedokun; Sambai, Caroline; Utembe, Wells; Opiyo, Rose; Awotidebe, Taofeek; Chirwa, Esnat; Nabakwe, Esther; Niragire, François; Uwizeye, Dieudonné; Niwemahoro, Celine; Kamndaya, Mphatso; Mwakalinga, Victoria; Otwombe, Kennedy

2014-01-01

Resolution of public health problems in Africa remains a challenge because of insufficient skilled human resource capacity. The Consortium for Advanced Research Training in Africa (CARTA) was established to enhance capacity in multi-disciplinary health research that will make a positive impact on population health in Africa. The first cohort of the CARTA program describes their perspectives and experiences during the 4 years of fellowship and puts forward suggestions for future progress and direction of research in Africa. The model of training as shown by the CARTA program is an effective model of research capacity building in African academic institutions. An expansion of the program is therefore warranted to reach out to more African academics in search of advanced research training.

A synthesis of sedimentary records of Australian environmental change during the last 2000 years

NASA Astrophysics Data System (ADS)

Tyler, J. J.; Karoly, D. J.; Gell, P.; Goodwin, I. D.

2013-12-01

Our understanding of Southern Hemispheric climate variability on multidecadal to multicentennial timescales is limited by a scarcity of quantitative, highly resolved climate records, a problem which is particularly manifest in Australia. To date there are no quantitative, annually resolved records from within continental Australia which extend further back in time than the most recent c. 300 years [Neukom and Gergis, 2012; PAGES 2k Consortium, 2013]. By contrast, a number of marine, lake, peat and speleothem sedimentary records exist, some of which span multiple millennia at sub-decadal resolution. Here we report a database of existing sedimentary records of environmental change in Australia [Freeman et al., 2011], of which 25 have sample resolutions < 100 years/sample and which span > 500 years in duration. The majority of these records are located in southeastern Australia, providing an invaluable resource with which to examine regional scale climate and environmental change. Although most of the records can not be quantitatively related to climate variability, Empirical Orthogonal Functions coupled with Monte Carlo iterative age modelling, demonstrate coherent patterns of environmental and ecological change. This coherency, as well as comparisons with a limited number of quantitative records, suggests that regional hydroclimatic changes were responsible for the observed patterns. Here, we discuss the implications of these findings with respect to Southern Hemisphere climate during the last 2000 years. In addition, we review the progress and potential of ongoing research in the region. References: Freeman, R., I. D. Goodwin, and T. Donovan (2011), Paleoclimate data synthesis and data base for the reconstruction of climate variability and impacts in NSW over the past 2000 years., Climate Futures Technical Report, 1/2011, 50 pages. Neukom, R., and J. Gergis (2012), Southern Hemisphere high-resolution palaeoclimate records of the last 2000 years, Holocene, 22(5), 501-524, doi:10.1177/0959683611427335. PAGES 2k Consortium (2013), Continental-scale temperature variability during the past two millennia, Nature Geoscience, 6, 339-346.

The AGTSR consortium: An update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fant, D.B.; Golan, L.P.

1995-10-01

The Advanced Gas Turbine Systems Research (AGTSR) program is a collaborative University-Industry R&D Consortium that is managed and administered by the South Carolina Energy R&D Center. AGTSR is a nationwide consortium dedicated to advancing land-based gas turbine systems for improving future power generation capability. It directly supports the technology-research arm of the ATS program and targets industry-defined research needs in the areas of combustion, heat transfer, materials, aerodynamics, controls, alternative fuels, and advanced cycles. The consortium is organized to enhance U.S. competitiveness through close collaboration with universities, government, and industry at the R&D level. AGTSR is just finishing its thirdmore » year of operation and is sponsored by the U.S. DOE - Morgantown Energy Technology Center. The program is scheduled to continue past the year 2000. At present, there are 78 performing member universities representing 36 states, and six cost-sharing U.S. gas turbine corporations. Three RFP`s have been announced and the fourth RFP is expected to be released in December, 1995. There are 31 research subcontracts underway at performing member universities. AGTSR has also organized three workshops, two in combustion and one in heat transfer. A materials workshop is in planning and is scheduled for February, 1996. An industrial internship program was initiated this past summer, with one intern positioned at each of the sponsoring companies. The AGTSR consortium nurtures close industry-university-government collaboration to enhance synergism and the transition of research results, accelerate and promote evolutionary-revolutionary R&D, and strives to keep a prominent U.S. industry strong and on top well into the 21st century. This paper will present the objectives and benefits of the AGTSR program, progress achieved to date, and future planned activity in fiscal year 1996.« less

Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ulm, Franz-Josef

2000-03-31

OAK-B135 Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 3(NOTE: Part II A item 1 indicates ''PAPER'', but a report is attached electronically)

Crosscutting Technology Development at the Center for Advanced Separation Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher E. Hull

2006-09-30

This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher E. Hull

2006-05-15

This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

The Development and Technical Adequacy of Seventh-Grade Reading Comprehension Measures in a Progress Monitoring Assessment System. Technical Report #1102

ERIC Educational Resources Information Center

Park, Bitnara Jasmine; Alonzo, Julie; Tindal, Gerald

2011-01-01

This technical report describes the process of development and piloting of reading comprehension measures that are appropriate for seventh-grade students as part of an online progress screening and monitoring assessment system, http://easycbm.com. Each measure consists of an original fictional story of approximately 1,600 to 1,900 words with 20…

Guide to DCP Study Close-Out: Milestones and Tasks | Division of Cancer Prevention

Cancer.gov

This guide assists Consortium Lead Organization (CLO) planning for DCP study close-out. Study close-out tasks are organized under milestones, which help mark progress toward completion of the close-out process. Once tasks associated with a milestone are underway, planning for the next milestone may begin. Click on a milestone to view the associated close-out tasks. |

InTASC Model Core Teaching Standards and Learning Progressions for Teachers 1.0: A Resource for Ongoing Teacher Development

ERIC Educational Resources Information Center

Council of Chief State School Officers, 2013

2013-01-01

The Council of Chief State School Officers (CCSSO), through its Interstate Teacher Assessment and Support Consortium (InTASC), offers this set of combined resources that define and support ongoing teacher effectiveness to ensure students reach college and career ready standards. This document includes the "InTASC Model Core Teaching…

25 CFR 1000.244 - May the Secretary suspend construction activities under an AFA?

Code of Federal Regulations, 2010 CFR

2010-04-01

... construction activities under an AFA? (a) The Secretary may require a Tribe/Consortium to suspend certain work under a construction portion of an AFA for up to 30 days only if: (1) Site conditions adversely affect health and safety; or (2) Work in progress or completed fails to substantially carry out the terms of the...

Improving Usage Statistics Processing for a Library Consortium: The Virtual Library of Virginia's Experience

ERIC Educational Resources Information Center

Matthews, Tansy E.

2009-01-01

This article describes the development of the Virtual Library of Virginia (VIVA). The VIVA statistics-processing system remains a work in progress. Member libraries will benefit from the ability to obtain the actual data from the VIVA site, rather than just the summaries, so a project to make these data available is currently being planned. The…

Military Suicide Research Consortium

DTIC Science & Technology

2014-10-01

increasing and decreasing (or even ceasing entirely) across different periods of time but still building on itself with each progressive episode...community from suicide. One study found that social norms, high levels of support, identification with role models , and high self-esteem help pro - tect...in follow-up. o Conducted quality control checks of clinical data . Monitored safety, adverse events for DSMB reporting. Initiated Database

Use of common analgesic medications and ovarian cancer survival: results from a pooled analysis in the Ovarian Cancer Association Consortium

PubMed Central

Dixon, Suzanne C; Nagle, Christina M; Wentzensen, Nicolas; Trabert, Britton; Beeghly-Fadiel, Alicia; Schildkraut, Joellen M; Moysich, Kirsten B; deFazio, Anna; Risch, Harvey A; Rossing, Mary Anne; Doherty, Jennifer A; Wicklund, Kristine G; Goodman, Marc T; Modugno, Francesmary; Ness, Roberta B; Edwards, Robert P; Jensen, Allan; Kjær, Susanne K; Høgdall, Estrid; Berchuck, Andrew; Cramer, Daniel W; Terry, Kathryn L; Poole, Elizabeth M; Bandera, Elisa V; Paddock, Lisa E; Anton-Culver, Hoda; Ziogas, Argyrios; Menon, Usha; Gayther, Simon A; Ramus, Susan J; Gentry-Maharaj, Aleksandra; Pearce, Celeste Leigh; Wu, Anna H; Pike, Malcolm C; Webb, Penelope M

2017-01-01

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with improved survival in some cancers, but evidence for ovarian cancer is limited. Methods: Pooling individual-level data from 12 Ovarian Cancer Association Consortium studies, we evaluated the association between self-reported, pre-diagnosis use of common analgesics and overall/progression-free/disease-specific survival among 7694 women with invasive epithelial ovarian cancer (4273 deaths). Results: Regular analgesic use (at least once per week) was not associated with overall survival (pooled hazard ratios, pHRs (95% confidence intervals): aspirin 0.96 (0.88–1.04); non-aspirin NSAIDs 0.97 (0.89–1.05); acetaminophen 1.01 (0.93–1.10)), nor with progression-free/disease-specific survival. There was however a survival advantage for users of any NSAIDs in studies clearly defining non-use as less than once per week (pHR=0.89 (0.82–0.98)). Conclusions: Although this study did not show a clear association between analgesic use and ovarian cancer survival, further investigation with clearer definitions of use and information about post-diagnosis use is warranted. PMID:28350790

Generation and focusing of pulsed intense ion beams. Technical progress report, 1 October 1982 - 30 September, 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hammer, D.A.; Kusse, B.R.; Sudan, R.N.

1983-07-01

The progress on this contract is described in three parts. The first deals with the technical operation of the LION accelerator. The second and third parts are concerned with the experimental results.

CRUSER (Consortium for Robotics and Unmanned Systems Education and Research)

DTIC Science & Technology

2013-07-08

LPI) comms: covert and innovative networks – such as the “Digital Semaphore ” concept being taken to field experimentation in FY13. 3)  UxS support of...Resolution Full Motion Video for Unmanned Systems and Remote Sensing Jeff Weekley, NPS Digital Semaphore Dr. Don Brutzman, NPS •  7-10 May 2012... Semaphore CRUSER  Thread  1   Sept  2011   Warfare   InnovaKon   Workshop   May  2012   Technical   ConKnuum   Apr  2013

UNAVCO facility support of NASA Dynamics of the Solid Earth (DOSE) GPS investigation for years 1995-1996

NASA Technical Reports Server (NTRS)

Ware, Randolph (Principal Investigator)

1996-01-01

This report consists of the following sections: a list of the NASA DOSE (Dynamics of the Solid Earth) Program Global Positioning System (GPS)-based campaigns supported by the UNAVCO (University Navstar Consortium) Boulder Facility; a list of NASA DOSE GPS permanent site installations supported by the UNAVCO Boulder Facility; and example science snapshots indicating the research projects supported with equipment and technical support available to DOSE Principal Investigators via the UNAVCO Boulder Facility.

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Kindergarten. Technical Report # 0921

ERIC Educational Resources Information Center

Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in kindergarten. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2008 and administered to approximately 2800 students from…

Launching a Novel Preclinical Infrastructure: Comparative Oncology Trials Consortium Directed Therapeutic Targeting of TNFα to Cancer Vasculature

PubMed Central

Mazcko, Christina; Hanna, Engy; Kachala, Stefan; LeBlanc, Amy; Newman, Shelley; Vail, David; Henry, Carolyn; Thamm, Douglas; Sorenmo, Karin; Hajitou, Amin; Pasqualini, Renata; Arap, Wadih

2009-01-01

Background Under the direction and sponsorship of the National Cancer Institute, we report on the first pre-clinical trial of the Comparative Oncology Trials Consortium (COTC). The COTC is a novel infrastructure to integrate cancers that naturally develop in pet dogs into the development path of new human drugs. Trials are designed to address questions challenging in conventional preclinical models and early phase human trials. Large animal spontaneous cancer models can be a valuable addition to successful studies of cancer biology and novel therapeutic drug, imaging and device development. Methodology/Principal Findings Through this established infrastructure, the first trial of the COTC (COTC001) evaluated a targeted AAV-phage vector delivering tumor necrosis factor (RGD-A-TNF) to αV integrins on tumor endothelium. Trial progress and data was reviewed contemporaneously using a web-enabled electronic reporting system developed for the consortium. Dose-escalation in cohorts of 3 dogs (n = 24) determined an optimal safe dose (5×1012 transducing units intravenous) of RGD-A-TNF. This demonstrated selective targeting of tumor-associated vasculature and sparing of normal tissues assessed via serial biopsy of both tumor and normal tissue. Repetitive dosing in a cohort of 14 dogs, at the defined optimal dose, was well tolerated and led to objective tumor regression in two dogs (14%), stable disease in six (43%), and disease progression in six (43%) via Response Evaluation Criteria in Solid Tumors (RECIST). Conclusions/Significance The first study of the COTC has demonstrated the utility and efficiency of the established infrastructure to inform the development of new cancer drugs within large animal naturally occurring cancer models. The preclinical evaluation of RGD-A-TNF within this network provided valuable and necessary data to complete the design of first-in-man studies. PMID:19330034

Japan's Methane Hydrate R&D Program, Accomplishments and Future Challenges

NASA Astrophysics Data System (ADS)

Shimada, T.

2009-12-01

JOGMEC have been searching for methane hydrate offshore around Japan for use as a future energy resource as a member of the research consortium of methane hydrate resources in Japan (MH21 Research Consortium). The MH21 Research Consortium was established in 2002 to carry out "Japan's Methane Hydrate R&D Program" published by the Ministry of Economy, Trade and Industry (METI) in July 2001. The program has been extended over 18 years (until 2018) and is divided into three phases. During phase 1, the following key accomplishments had been achieved. Revealed and confirmed the occurrence of methane hydrate filling pore spaces of sand layers in the marine environment for the first time in the eastern Nankai Trough. Established methodology to delineate the thick methane hydrate concentrated zones composed of alternations of highly hydrate-saturated turbidite sand mainly by geophysical measures. Evaluated the amount of gas trapped in the eastern Nankai Trough, applied a probabilistic method based on the borehole data and seismic data, contained in methane hydrate-bearing layers. Tested and achieved substantial methane gas production through the wellbore from subsurface hydrate-bearing layers by dissociating hydrates in Canadian arctic area under international collaboration. Both depressurization method and hot water circulation method were successfully conducted to produce methane gas, and the depressurization method was proved to be effective as a production method that could be utilized in the future. We accumulated a significant amount of knowledge and experience during phase 1. However, many technical and economic challenges still remain for the development of methane hydrate. The research program proceeded to phase 2 in 2009. This time we would like to present summary of phase 1 and challenges during phase 2. The author would like to express sincere appreciation to MH21 Research Consortium and METI for permission for this presentation.

The Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) collaborative quality improvement initiative in percutaneous coronary interventions.

PubMed

Moscucci, Mauro; Share, David; Kline-Rogers, Eva; O'Donnell, Michael; Maxwell-Eward, Ann; Meengs, William L; Clark, Vivian L; Kraft, Phillip; De Franco, Anthony C; Chambers, James L; Patel, Kirit; McGinnity, John G; Eagle, Kim A

2002-10-01

The past decade has been characterized by increased scrutiny of outcomes of surgical and percutaneous coronary interventions (PCIs). This increased scrutiny has led to the development of regional, state, and national databases for outcome assessment and for public reporting. This report describes the initial development of a regional, collaborative, cardiovascular consortium and the progress made so far by this collaborative group. In 1997, a group of hospitals in the state Michigan agreed to create a regional collaborative consortium for the development of a quality improvement program in interventional cardiology. The project included the creation of a comprehensive database of PCIs to be used for risk assessment, feedback on absolute and risk-adjusted outcomes, and sharing of information. To date, information from nearly 20,000 PCIs have been collected. A risk prediction tool for death in the hospital and additional risk prediction tools for other outcomes have been developed from the data collected, and are currently used by the participating centers for risk assessment and for quality improvement. As the project enters into year 5, the participating centers are deeply engaged in the quality improvement phase, and expansion to a total of 17 hospitals with active PCI programs is in process. In conclusion, the Blue Cross Blue Shield of Michigan Cardiovascular Consortium is an example of a regional collaborative effort to assess and improve quality of care and outcomes that overcome the barriers of traditional market and academic competition.

The development of coal-based technologies for Department of Defense facilities. Volume 1, Technical report. Semiannual technical progress report, September 28, 1994--March 27, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, B.G.; Bartley, D.A.; Hatcher, P.

1996-10-15

This program is being conducted as a cooperative agreement between the Consortium for Coal Water Mixture Technology and the U.S. Department of Energy. Activities this reporting period are summarized by phase. Phase I is nearly completed. During this reporting period, coal beneficiation/preparation studies, engineering designs and economics for retrofitting the Crane, Indiana boiler to fire coal-based fuels, and a 1,000-hour demonstration of dry, micronized coal were completed. In addition, a demonstration-scale micronized-coal water mixture (MCWM) preparation circuit was constructed and a 1,000-hour demonstration firing MCWM began. Work in Phase II focused on emissions reductions, coal beneficiation/preparation studies, and economic analysesmore » of coal use. Emissions reductions investigations involved literature surveys of NO{sub x}, SO{sub 2}, trace metals, volatile organic compounds, and fine particulate matter capture. In addition, vendors and engineering firms were contacted to identify the appropriate emissions technologies for the installation of commercial NO{sub x} and SO{sub 2} removal systems on the demonstration boiler. Information from the literature surveys and engineering firms will be used to identify, design, and install a control system(s). Work continued on the refinement and optimization of coal grinding and MCWM preparation procedures, and on the development of advanced processes for beneficiating high ash, high sulfur coals. Work also continued on determining the basic cost estimation of boiler retrofits, and evaluating environmental, regulatory, and regional economic impacts. In addition, the feasibility of technology adoption, and the public`s perception of the benefits and costs of coal usage was studied. A coal market analysis was completed. Work in Phase III focused on coal preparation studies, emissions reductions and economic analyses of coal use.« less

National Alliance for Advance Biofuels and Bio-Products Final Technical Report Addendum Hydrothermal Processing Pilot System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oyler, James R.

2015-12-21

The main objective of the NAABB was to combine science, technology, and engineering expertise from across the nation to break down critical technical barriers to commercialization of algae-based biofuels. As a part of the consortium, Genifuel’s NAABB goals was to fabricate and demonstrate a pilot-scale system to convert algae into fuels. The purpose of this pilot system was to show that processes developed in the laboratory at bench-scale during the program could be successfully scaled up to a pre-commercial level, and thereby provide visibility into the ultimate viability and cost of algae biofuels. The pilot system has now been completedmore » and tested, and this report documents what has been achieved.« less

The boot software of the control unit of the near infrared spectrograph of the Euclid space mission: technical specification

NASA Astrophysics Data System (ADS)

Gómez-Sáenz-de-Tejada, Jaime; Toledo-Moreo, Rafael; Colodro-Conde, Carlos; Pérez-Lizán, David; Fernández-Conde, Jesús; Sánchez-Prieto, Sebastián.

2016-07-01

The Near Infrared Spectrograph and Photometer (NISP) is one of the instruments on board the ESA EUCLID mission. The Boot Software (BSW) is in charge of initialization and communications after a reset occurs at hard- ware level. The Universidad Politecnica de Cartagena and Instituto de Astrofisica de Canarias are responsible of the Instrument Control Unit of the NISP (NI-ICU) in the Euclid Consortium. The NI-ICU BSW is developed by Universidad de Alcaĺa, and its main functions are: communication with the S/C for memory management, self-tests and start of a patchable Application Software (ASW). This paper presents the NI-ICU BSW status of definition and design at the end of the Technical Specification phase.

Assessment Program Technical Progress Report, 1996-1997.

ERIC Educational Resources Information Center

McCown, Laurie; Fanning, Erin; Eickmeyer, Barbara

Coconino Community College (CCC) annually assesses its institutional effectiveness to demonstrate its commitment to improving programs and services to students. The 1996-97 Assessment Program Technical Progress Report records the assessment and institutional activities enacted during the academic year, detailing the assessment model, timelines,…

Preliminary Design of Winged Experimental Rocket by University Consortium

NASA Astrophysics Data System (ADS)

Wakita, Masashi; Yonemoto, Koichi; Akiyama, Tomoki; Aso, Shigeru; Kohsetsu, Yuji; Nagata, Harunori

The project of Winged Experimental Rocket described here is a proposal by the alliance of universities (University Consortium) expanding and integrating the research activities of reusable space transportation system performed by individual universities, and is the proposal that aims at flight proof of the results of advanced research conducted by the universities and JAXA using the university-centered experimental launch systems. This paper verifies the validity of the winged experimental rocket by surveying the technical issues that should be demonstrated and by estimating the airframe scale, weight and finally the total cost. The development schedule of this project was set to five years, where two airframes of different scales will be developed to minimize the risks. A 1.5-meter-long airframe will be first manufactured and conduct flight tests in the third year to verify the design issues. Then, a 2.5-meter-long airframe will be finally developed and conduct a complete flight demonstration of various research issues in the fifth year.

Re-energizing energy supply: Electrolytically-produced hydrogen as a flexible energy storage medium and fuel for road transport

NASA Astrophysics Data System (ADS)

Emonts, Bernd; Schiebahn, Sebastian; Görner, Klaus; Lindenberger, Dietmar; Markewitz, Peter; Merten, Frank; Stolten, Detlef

2017-02-01

"Energiewende", which roughly translates as the transformation of the German energy sector in accordance with the imperatives of climate change, may soon become a byword for the corresponding processes most other developed countries are at various stages of undergoing. Germany's notable progress in this area offers valuable insights that other states can draw on in implementing their own transitions. The German state of North Rhine-Westphalia (NRW) is making its own contribution to achieving the Energiewende's ambitious objectives: in addition to funding an array of 'clean and green' projects, the Virtual Institute Power to Gas and Heat was established as a consortium of seven scientific and technical organizations whose aim is to inscribe a future, renewable-based German energy system with adequate flexibility. Thus, it is tasked with conceiving of and evaluating suitable energy path options. This paper outlines one of the most promising of these pathways, which is predicated on the use of electrolytically-produced hydrogen as an energy storage medium, as well as the replacement of hydrocarbon-based fuel for most road vehicles. We describe and evaluate this path and place it in a systemic context, outlining a case study from which other countries and federated jurisdictions therein may draw inspiration.

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 1. Technical Report # 0919

ERIC Educational Resources Information Center

Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grade 1. These measures, available as part of easyCBM [TM], an online progress monitoring assessment system, were developed in 2008 and administered to approximately 2800 students from schools…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 3. Technical Report # 09-02

ERIC Educational Resources Information Center

Alonzo, Julie; Lai, Cheng Fei; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 2. Technical Report # 0920

ERIC Educational Resources Information Center

Alonzo, Julie; Lai, Cheng Fei; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 5. Technical Report # 09-01

ERIC Educational Resources Information Center

Lai, Cheng Fei; Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 4. Technical Report # 09-03

ERIC Educational Resources Information Center

Alonzo, Julie; Lai, Cheng Fei; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 7. Technical Report 0908

ERIC Educational Resources Information Center

Lai, Cheng Fei; Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 8. Technical Report # 09-04

ERIC Educational Resources Information Center

Lai, Cheng Fei; Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

Semi-Quantitative Imaging Biomarkers of Knee Osteoarthritis Progression: Data from the FNIH OA Biomarkers Consortium

PubMed Central

Collins, Jamie E.; Losina, Elena; Nevitt, Michael C.; Roemer, Frank W.; Guermazi, Ali; Lynch, John A.; Katz, Jeffrey N.; Kwoh, C. Kent; Kraus, Virginia B.; Hunter, David J.

2017-01-01

Objective To determine the association between changes in semi-quantitative knee MRI biomarkers over 24 months and radiographic and pain progression over 48 months in knees with mild to moderate osteoarthritis. Methods We undertook a nested case-control study as part of the Osteoarthritis Biomarkers Consortium Project. We built multivariable logistic regression models to examine the association between change over 24 months in semi-quantitative MR imaging markers and knee OA radiographic and pain progression. MRIs were read according to the MRI Osteoarthritis Knee Score (MOAKS) scoring system. We focused on changes in cartilage, osteophytes, meniscus, bone marrow lesions, Hoffa-synovitis, and synovitis-effusion. Results The most parsimonious model included changes in cartilage thickness and surface area, synovitis-effusion, Hoffa-synovitis, and meniscal morphology (C-statistic =0.740). Subjects with worsening cartilage thickness in 3+ subregions vs. no worsening had 2.8-fold (95% CI: 1.3 – 5.9) greater odds of being a case while subjects with worsening in cartilage surface area in 3+ subregions vs. no worsening had 2.4-fold (95% CI: 1.3 – 4.4) greater odds of being a case. Having worsening in any region in meniscal morphology was associated with a 2.2-fold (95%CI: 1.3 – 3.8) greater odds of being a case. Worsening synovitis-effusion (OR=2.7) and Hoffa-synovitis (OR=2.0) were also associated with greater odds of being a case. Conclusion Twenty-four-month change in cartilage thickness, cartilage surface area, synovitis-effusion, Hoffa-synovitis, and meniscal morphology were independently associated with OA progression, suggesting that they may serve as efficacy biomarkers in clinical trials of disease modifying interventions for knee OA. PMID:27111771

Developing a mesophilic co-culture for direct conversion of cellulose to butanol in consolidated bioprocess.

PubMed

Wang, Zhenyu; Cao, Guangli; Zheng, Ju; Fu, Defeng; Song, Jinzhu; Zhang, Junzheng; Zhao, Lei; Yang, Qian

2015-01-01

Consolidated bioprocessing (CBP) of butanol production from cellulosic biomass is a promising strategy for cost saving compared to other processes featuring dedicated cellulase production. CBP requires microbial strains capable of hydrolyzing biomass with enzymes produced on its own with high rate and high conversion and simultaneously produce a desired product at high yield. However, current reported butanol-producing candidates are unable to utilize cellulose as a sole carbon source and energy source. Consequently, developing a co-culture system using different microorganisms by taking advantage of their specific metabolic capacities to produce butanol directly from cellulose in consolidated bioprocess is of great interest. This study was mainly undertaken to find complementary organisms to the butanol producer that allow simultaneous saccharification and fermentation of cellulose to butanol in their co-culture under mesophilic condition. Accordingly, a highly efficient and stable consortium N3 on cellulose degradation was first developed by multiple subcultures. Subsequently, the functional microorganisms with 16S rRNA sequences identical to the denaturing gradient gel electrophoresis (DGGE) profile were isolated from consortium N3. The isolate Clostridium celevecrescens N3-2 exhibited higher cellulose-degrading capability was thus chosen as the partner strain for butanol production with Clostridium acetobutylicum ATCC824. Meanwhile, the established stable consortium N3 was also investigated to produce butanol by co-culturing with C. acetobutylicum ATCC824. Butanol was produced from cellulose when C. acetobutylicum ATCC824 was co-cultured with either consortium N3 or C. celevecrescens N3-2. Co-culturing C. acetobutylicum ATCC824 with the stable consortium N3 resulted in a relatively higher butanol concentration, 3.73 g/L, and higher production yield, 0.145 g/g of glucose equivalent. The newly isolated microbial consortium N3 and strain C. celevecrescens N3-2 displayed effective degradation of cellulose and produced considerable amounts of butanol when they were co-cultured with C. acetobutylicum ATCC824. This is the first report of application of co-culture to produce butanol directly from cellulose under mesophilic condition. Our results indicated that co-culture of mesophilic cellulolytic microbe and butanol-producing clostridia provides a technically feasible and more simplified way for producing butanol directly from cellulose.

GAS STORAGE TECHNOLGOY CONSORTIUM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert W. Watson

2004-04-23

Gas storage is a critical element in the natural gas industry. Producers, transmission and distribution companies, marketers, and end users all benefit directly from the load balancing function of storage. The unbundling process has fundamentally changed the way storage is used and valued. As an unbundled service, the value of storage is being recovered at rates that reflect its value. Moreover, the marketplace has differentiated between various types of storage services, and has increasingly rewarded flexibility, safety, and reliability. The size of the natural gas market has increased and is projected to continue to increase towards 30 trillion cubic feetmore » (TCF) over the next 10 to 15 years. Much of this increase is projected to come from electric generation, particularly peaking units. Gas storage, particularly the flexible services that are most suited to electric loads, is critical in meeting the needs of these new markets. In order to address the gas storage needs of the natural gas industry, an industry-driven consortium was created--the Gas Storage Technology Consortium (GSTC). The objective of the GSTC is to provide a means to accomplish industry-driven research and development designed to enhance operational flexibility and deliverability of the Nation's gas storage system, and provide a cost effective, safe, and reliable supply of natural gas to meet domestic demand. To accomplish this objective, the project is divided into three phases that are managed and directed by the GSTC Coordinator. Base funding for the consortium is provided by the U.S. Department of Energy (DOE). In addition, funding is anticipated from the Gas Technology Institute (GTI). The first phase, Phase 1A, was initiated on September 30, 2003, and is scheduled for completion on March 31, 2004. Phase 1A of the project includes the creation of the GSTC structure, development of constitution (by-laws) for the consortium, and development and refinement of a technical approach (work plan) for deliverability enhancement and reservoir management. This report deals with the first 3-months of the project and encompasses the period September 30, 2003, through December 31, 2003. During this 3-month period, the first meeting of individuals representing the storage industry, universities and the Department of energy was held. The purpose of this meeting was to initiate the dialogue necessary to for the creation and adoption of a constitution that would be used to govern the activities of the consortium.« less

GAS STORAGE TECHNOLOGY CONSORTIUM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert W. Watson

2004-04-17

Gas storage is a critical element in the natural gas industry. Producers, transmission and distribution companies, marketers, and end users all benefit directly from the load balancing function of storage. The unbundling process has fundamentally changed the way storage is used and valued. As an unbundled service, the value of storage is being recovered at rates that reflect its value. Moreover, the marketplace has differentiated between various types of storage services, and has increasingly rewarded flexibility, safety, and reliability. The size of the natural gas market has increased and is projected to continue to increase towards 30 trillion cubic feetmore » (TCF) over the next 10 to 15 years. Much of this increase is projected to come from electric generation, particularly peaking units. Gas storage, particularly the flexible services that are most suited to electric loads, is critical in meeting the needs of these new markets. In order to address the gas storage needs of the natural gas industry, an industry-driven consortium was created--the Gas Storage Technology Consortium (GSTC). The objective of the GSTC is to provide a means to accomplish industry-driven research and development designed to enhance operational flexibility and deliverability of the Nation's gas storage system, and provide a cost effective, safe, and reliable supply of natural gas to meet domestic demand. To accomplish this objective, the project is divided into three phases that are managed and directed by the GSTC Coordinator. Base funding for the consortium is provided by the U.S. Department of Energy (DOE). In addition, funding is anticipated from the Gas Technology Institute (GTI). The first phase, Phase 1A, was initiated on September 30, 2003, and is scheduled for completion on March 31, 2004. Phase 1A of the project includes the creation of the GSTC structure, development of constitution (by-laws) for the consortium, and development and refinement of a technical approach (work plan) for deliverability enhancement and reservoir management. This report deals with the second 3-months of the project and encompasses the period December 31, 2003, through March 31, 2003. During this 3-month, the dialogue of individuals representing the storage industry, universities and the Department of energy was continued and resulted in a constitution for the operation of the consortium and a draft of the initial Request for Proposals (RFP).« less

Developing a Radiation Protection Hub

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hertel, Nolan E

The WARP report issued by the NCRP study committee estimates that in ten years there will be a human capital crisis across the radiation safety community. The ability to respond to this shortage will be amplified by the fact that many radiation protection (health physics) academic programs will find it difficult to justify their continued existence since they are low volume programs, both in terms of enrollment and research funding, compared to the research funding return and visibility of more highly subscribed and highly funded academic disciplines. In addition, across the national laboratory complex, radiation protection research groups have beenmore » disbanded or dramatically reduced in size. The loss of both of these national resources is being accelerated by low and uncertain government funding priorities. The most effective solution to this problem would be to form a consortium that would bring together the radiation protection research, academic and training communities. The goal of such a consortium would be to engage in research, education and training of the next generation of radiation protection professionals. Furthermore the consortium could bring together the strengths of different universities, national laboratory programs and other entities in a strategic manner to accomplish a multifaceted research, educational and training agenda. This vision would forge a working and funded relationship between major research universities, national labs, four-year degree institutes, technical colleges and other partners.« less

Developing A Radiation Protection Hub.

PubMed

Hertel, Nolan E

2017-02-01

The Where are the Radiation Professionals (WARP)? statement issued by the National Council on Radiation Protection and Measurements estimates that in 10 y, there will be a human capital crisis across the radiation safety community. The ability to respond to this shortage will be amplified by the fact that many radiation protection (health physics) academic programs will find it difficult to justify their continued existence since they are low-volume programs, both in terms of enrollment and research funding, compared to the research funding return and visibility of more highly subscribed and highly funded academic disciplines. In addition, across the national laboratory complex, radiation protection research groups have been disbanded or dramatically reduced in size. The loss of both of these national resources is being accelerated by low and uncertain government funding priorities. The most effective solution to this problem would be to form a consortium that would bring together the radiation protection research, academic, and training communities. The goal of such a consortium would be to engage in research, education, and training of the next generation of radiation protection professionals. Furthermore, the consortium could bring together the strengths of different universities, national laboratory programs, and other entities in a strategic manner to accomplish a multifaceted research, educational, and training agenda. This vision would forge a working and funded relationship between major research universities, national laboratories, 4-y degree institutions, technical colleges, and other partners.

Mission Connect Mild TBI Translational Research Consortium

DTIC Science & Technology

2013-08-01

year 2 and 3 annual progress report we completed the morphometric and the diffusion tensor imaging (DTI) in cortical impact injury with and without...and morphometric measures. Response to EAB feedback: No concerns were expressed by the External Advisory Board about the MRI core. Manuscript...automatic analysis of morphometry, DTI, and MTR for both humans and rodents.  Completed morphometric and DTI analysis in traumatically injured animals

The Evolution of the Taliban

DTIC Science & Technology

2008-06-01

Charismatic Leaders," T + D (March 1, 2003), 46, http://www.proquest.com/ (accessed December 2, 2007). 22 The Taliban made rapid military progress...Almond, R . Scott Appleby and Emmanuel Sivan, Strong Religion : The Rise of Fundamentalisms Around the World (Chicago: University of Chicago Press, 2003...For details see "Frontier Corps," Pakistan Military Consortium, http://www.pakdef.info/forum/showthread.php? t =5300 , (accessed January 11, 2008). 68

USSR Report, International Affairs

DTIC Science & Technology

1986-03-04

AFRIKA SEGODNYA, No 10, Oct 85).. 50 Socioeconomic Progress, Problems in Nigeria Viewed (V. Novikov; AZIYA I AFRIKA SEGODNYA, No 10, Oct 85...USSR, for example, Nigeria is carrying out the construc- tion of a metallurgical plant. The light-section and wire mills for this enterprise...and Poland created a consortium to build an agrarian complex in Nigeria for growing and processing sugar-cane. Having achieved some definite

SUPPORT OF GULF OF MEXICO HYDRATE RESEARCH CONSORTIUM: ACTIVITIES TO SUPPORT ESTABLISHMENT OF A SEA FLOOR MONITORING STATION PROJECT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paul Higley; J. Robert Woolsey; Ralph Goodman

2005-08-01

A Consortium, designed to assemble leaders in gas hydrates research, has been established at the University of Mississippi's Center for Marine Resources and Environmental Technology, CMRET. The primary objective of the group is to design and emplace a remote monitoring station on the sea floor in the northern Gulf of Mexico by the year 2005, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission necessitates assembling a station that will monitor physical and chemical parameters of the sea water and sea floor sediments on a more-or-less continuous basis overmore » an extended period of time. Development of the station allows for the possibility of expanding its capabilities to include biological monitoring, as a means of assessing environmental health. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in this relatively new research arena. Complementary expertise, both scientific and technical, has been assembled to innovate research methods and construct necessary instrumentation. A year into the life of this cooperative agreement, we note the following achievements: (1) Progress on the vertical line array (VLA) of sensors: (A) Software and hardware upgrades to the data logger for the prototype vertical line array, including enhanced programmable gains, increased sampling rates, improved surface communications, (B) Cabling upgrade to allow installation of positioning sensors, (C) Adaptation of SDI's Angulate program to use acoustic slant ranges and DGPS data to compute and map the bottom location of the vertical array, (D) Progress in T''0'' delay and timing issues for improved control in data recording, (E) Successful deployment and recovery of the VLA twice during an October, 2003 cruise, once in 830m water, once in 1305m water, (F) Data collection and recovery from the DATS data logger, (G) Sufficient energy supply and normal functioning of the pressure compensated battery even following recharge after the first deployment, (H) Survival of the acoustic modem following both deployments though it was found to have developed a slow leak through the transducer following the second deployment due, presumably, to deployment in excess of 300m beyond its rating. (2) Progress on the Sea Floor Probe: (A) The Sea Floor Probe and its delivery system, the Multipurpose sled have been completed, (B) The probe has been modified to penetrate the <1m blanket of hemipelagic ooze at the water/sea floor interface to provide the necessary coupling of the accelerometer with the denser underlying sediments, (C) The MPS has been adapted to serve as an energy source for both p- and s-wave studies at the station as well as to deploy the horizontal line arrays and the SFP. (3) Progress on the Electromagnetic Bubble Detector and Counter: (A) Components for the prototype have been assembled, including a dedicated microcomputer to control power, readout and logging of the data, all at an acceptable speed, (B) The prototype has been constructed and preliminary data collected, (C) The construction of the field system is underway. (4) Progress on the Acoustic Systems for Monitoring Gas Hydrates: (A) Video recordings of bubbles emitted from a seep in Mississippi Canyon have been made from a submersible dive and the bubbles analyzed with respect to their size, number, and rise rate. These measurements have been used to determine the parameters to build the system capable of measuring gas escaping at the site of the monitoring station, (B) Laboratory tests performed using the project prototype have produced a conductivity data set that is being used to refine parameters of the field model. (5) Progress on the Mid-Infrared Sensor for Continuous Methane Monitoring: (A) Preliminary designs of mounting pieces for electrical components of ''sphereIR'' have been completed using AutoCAD software, (B) The preliminary design of an electronics baseplate has been completed and aided in the optimization of positioning electrical components inside the instrument housing, (C) First spectroscopic investigations of the highly permeable polymer, poly(trimethylsilyl)propyne (PTMSP), as a potential sensing membrane for methane, have commenced, (D) High-pressure multireflection ATR measurements were continued during this project period to investigate the potential influences of hydrostatic pressure on sensing principles and data evaluation strategies. (6) Progress on the Seismo-acoustic Characterization of Sea Floor Properties and Processes at the Hydrate Monitoring Station: (A) work has concentrated on the design and building of the hardware, bench testing and preliminary field trials, (B) development work to extend the capability of the electronics to allow remote operation on the seabed for up to 3 months at a time done.« less

Development and Validation of a Novel Scoring System for Predicting Technical Success of Chronic Total Occlusion Percutaneous Coronary Interventions: The PROGRESS CTO (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention) Score.

PubMed

Christopoulos, Georgios; Kandzari, David E; Yeh, Robert W; Jaffer, Farouc A; Karmpaliotis, Dimitri; Wyman, Michael R; Alaswad, Khaldoon; Lombardi, William; Grantham, J Aaron; Moses, Jeffrey; Christakopoulos, Georgios; Tarar, Muhammad Nauman J; Rangan, Bavana V; Lembo, Nicholas; Garcia, Santiago; Cipher, Daisha; Thompson, Craig A; Banerjee, Subhash; Brilakis, Emmanouil S

2016-01-11

This study sought to develop a novel parsimonious score for predicting technical success of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) performed using the hybrid approach. Predicting technical success of CTO PCI can facilitate clinical decision making and procedural planning. We analyzed clinical and angiographic parameters from 781 CTO PCIs included in PROGRESS CTO (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention) using a derivation and validation cohort (2:1 sampling ratio). Variables with strong association with technical success in multivariable analysis were assigned 1 point, and a 4-point score was developed from summing all points. The PROGRESS CTO score was subsequently compared with the J-CTO (Multicenter Chronic Total Occlusion Registry in Japan) score in the validation cohort. Technical success was 92.9%. On multivariable analysis, factors associated with technical success included proximal cap ambiguity (beta coefficient [b] = 0.88), moderate/severe tortuosity (b = 1.18), circumflex artery CTO (b = 0.99), and absence of "interventional" collaterals (b = 0.88). The resulting score demonstrated good calibration and discriminatory capacity in the derivation (Hosmer-Lemeshow chi-square = 2.633; p = 0.268, and receiver-operator characteristic [ROC] area = 0.778) and validation (Hosmer-Lemeshow chi-square = 5.333; p = 0.070, and ROC area = 0.720) subset. In the validation cohort, the PROGRESS CTO and J-CTO scores performed similarly in predicting technical success (ROC area 0.720 vs. 0.746, area under the curve difference = 0.026, 95% confidence interval = -0.093 to 0.144). The PROGRESS CTO score is a novel useful tool for estimating technical success in CTO PCI performed using the hybrid approach. Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Final report : for the period of December 1999 through November 30, 2000 : Florida Transit Training Program (1999/2000) : Florida Technical Assistance Program (1999/2000)

DOT National Transportation Integrated Search

2000-01-01

The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program. The following progress report is intended to highlight the significant activities of th...

Annual progress report : for the period of January 2001 through December 2001 : Florida Transit Training Program (2001) : Florida Technical Assistance Program (2001)

DOT National Transportation Integrated Search

2001-01-01

The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program for the 2001 year. Activities of the Florida Statewide Transit Training Program are pres...

Establishing Transportation Framework Services Using the Open Geospatial Consortium Web Feature Service Specification

NASA Astrophysics Data System (ADS)

Yang, C.; Wong, D. W.; Phillips, T.; Wright, R. A.; Lindsey, S.; Kafatos, M.

2005-12-01

As a teamed partnership of the Center for Earth Observing and Space Research (CEOSR) at George Mason University (GMU), Virginia Department of Transportation (VDOT), Bureau of Transportation Statistics at the Department of Transportation (BTS/DOT), and Intergraph, we established Transportation Framework Data Services using Open Geospatial Consortium (OGC)'s Web Feature Service (WFS) Specification to enable the sharing of transportation data among the federal level with data from BTS/DOT, the state level through VDOT, the industries through Intergraph. CEOSR develops WFS solutions using Intergraph software. Relevant technical documents are also developed and disseminated through the partners. The WFS is integrated with operational geospatial systems at CEOSR and VDOT. CEOSR works with Intergraph on developing WFS solutions and technical documents. GeoMedia WebMap WFS toolkit is used with software and technical support from Intergraph. ESRI ArcIMS WFS connector is used with GMU's campus license of ESRI products. Tested solutions are integrated with framework data service operational systems, including 1) CEOSR's interoperable geospatial information services, FGDC clearinghouse Node, Geospatial One Stop (GOS) portal, and WMS services, 2) VDOT's state transportation data and GIS infrastructure, and 3)BTS/DOT's national transportation data. The project presents: 1) develop and deploy an operational OGC WFS 1.1 interfaces at CEOSR for registering with FGDC/GOS Portal and responding to Web ``POST'' requests for transportation Framework data as listed in Table 1; 2) build the WFS service that can return the data that conform to the drafted ANSI/INCITS L1 Standard (when available) for each identified theme in the format given by OGC Geography Markup Language (GML) Version 3.0 or higher; 3) integrate the OGC WFS with CEOSR's clearinghouse nodes, 4) establish a formal partnership to develop and share WFS-based geospatial interoperability technology among GMU, VDOT, BTS/DOT, and Intergraph; and 5) develop WFS-based solutions and technical documents using the GeoMedia WebMap WFS toolkit. Geospatial Web Feature Service is demonstrated to be more efficient in sharing vector data and supports direct Internet access transportation data. Developed WFS solutions also enhanced the interoperable service provided by CEOSR through the FGDC clearinghouse node and the GOS Portal.

76 FR 64083 - Reliability Technical Conference; Notice of Technical Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-17

... Technical Conference; Notice of Technical Conference Take notice that the Federal Energy Regulatory Commission will hold a Technical Conference on Tuesday, November 29, 2011, from 1 p.m. to 5 p.m. and... System. The conference will explore the progress made on the priorities for addressing risks to...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2014 CFR

2014-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Preparation of technical...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2012 CFR

2012-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Preparation of technical...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2010 CFR

2010-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Preparation of technical...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2013 CFR

2013-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Preparation of technical...

48 CFR 2052.211-70 - Preparation of technical reports.

Code of Federal Regulations, 2011 CFR

2011-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Preparation of technical...

A novel cross-disciplinary multi-institute approach to translational cancer research: lessons learned from Pennsylvania Cancer Alliance Bioinformatics Consortium (PCABC).

PubMed

Patel, Ashokkumar A; Gilbertson, John R; Showe, Louise C; London, Jack W; Ross, Eric; Ochs, Michael F; Carver, Joseph; Lazarus, Andrea; Parwani, Anil V; Dhir, Rajiv; Beck, J Robert; Liebman, Michael; Garcia, Fernando U; Prichard, Jeff; Wilkerson, Myra; Herberman, Ronald B; Becich, Michael J

2007-06-08

The Pennsylvania Cancer Alliance Bioinformatics Consortium (PCABC, http://www.pcabc.upmc.edu) is one of the first major project-based initiatives stemming from the Pennsylvania Cancer Alliance that was funded for four years by the Department of Health of the Commonwealth of Pennsylvania. The objective of this was to initiate a prototype biorepository and bioinformatics infrastructure with a robust data warehouse by developing a statewide data model (1) for bioinformatics and a repository of serum and tissue samples; (2) a data model for biomarker data storage; and (3) a public access website for disseminating research results and bioinformatics tools. The members of the Consortium cooperate closely, exploring the opportunity for sharing clinical, genomic and other bioinformatics data on patient samples in oncology, for the purpose of developing collaborative research programs across cancer research institutions in Pennsylvania. The Consortium's intention was to establish a virtual repository of many clinical specimens residing in various centers across the state, in order to make them available for research. One of our primary goals was to facilitate the identification of cancer-specific biomarkers and encourage collaborative research efforts among the participating centers. The PCABC has developed unique partnerships so that every region of the state can effectively contribute and participate. It includes over 80 individuals from 14 organizations, and plans to expand to partners outside the State. This has created a network of researchers, clinicians, bioinformaticians, cancer registrars, program directors, and executives from academic and community health systems, as well as external corporate partners - all working together to accomplish a common mission. The various sub-committees have developed a common IRB protocol template, common data elements for standardizing data collections for three organ sites, intellectual property/tech transfer agreements, and material transfer agreements that have been approved by each of the member institutions. This was the foundational work that has led to the development of a centralized data warehouse that has met each of the institutions' IRB/HIPAA standards. Currently, this "virtual biorepository" has over 58,000 annotated samples from 11,467 cancer patients available for research purposes. The clinical annotation of tissue samples is either done manually over the internet or semi-automated batch modes through mapping of local data elements with PCABC common data elements. The database currently holds information on 7188 cases (associated with 9278 specimens and 46,666 annotated blocks and blood samples) of prostate cancer, 2736 cases (associated with 3796 specimens and 9336 annotated blocks and blood samples) of breast cancer and 1543 cases (including 1334 specimens and 2671 annotated blocks and blood samples) of melanoma. These numbers continue to grow, and plans to integrate new tumor sites are in progress. Furthermore, the group has also developed a central web-based tool that allows investigators to share their translational (genomics/proteomics) experiment data on research evaluating potential biomarkers via a central location on the Consortium's web site. The technological achievements and the statewide informatics infrastructure that have been established by the Consortium will enable robust and efficient studies of biomarkers and their relevance to the clinical course of cancer. Studies resulting from the creation of the Consortium may allow for better classification of cancer types, more accurate assessment of disease prognosis, a better ability to identify the most appropriate individuals for clinical trial participation, and better surrogate markers of disease progression and/or response to therapy.

Evaluating efforts to diversify the biomedical workforce: the role and function of the Coordination and Evaluation Center of the Diversity Program Consortium.

PubMed

McCreath, Heather E; Norris, Keith C; Calderόn, Nancy E; Purnell, Dawn L; Maccalla, Nicole M G; Seeman, Teresa E

2017-01-01

The National Institutes of Health (NIH)-funded Diversity Program Consortium (DPC) includes a Coordination and Evaluation Center (CEC) to conduct a longitudinal evaluation of the two signature, national NIH initiatives - the Building Infrastructure Leading to Diversity (BUILD) and the National Research Mentoring Network (NRMN) programs - designed to promote diversity in the NIH-funded biomedical, behavioral, clinical, and social sciences research workforce. Evaluation is central to understanding the impact of the consortium activities. This article reviews the role and function of the CEC and the collaborative processes and achievements critical to establishing empirical evidence regarding the efficacy of federally-funded, quasi-experimental interventions across multiple sites. The integrated DPC evaluation is particularly significant because it is a collaboratively developed Consortium Wide Evaluation Plan and the first hypothesis-driven, large-scale systemic national longitudinal evaluation of training programs in the history of NIH/National Institute of General Medical Sciences. To guide the longitudinal evaluation, the CEC-led literature review defined key indicators at critical training and career transition points - or Hallmarks of Success. The multidimensional, comprehensive evaluation of the impact of the DPC framed by these Hallmarks is described. This evaluation uses both established and newly developed common measures across sites, and rigorous quasi-experimental designs within novel multi-methods (qualitative and quantitative). The CEC also promotes shared learning among Consortium partners through working groups and provides technical assistance to support high-quality process and outcome evaluation internally of each program. Finally, the CEC is responsible for developing high-impact dissemination channels for best practices to inform peer institutions, NIH, and other key national and international stakeholders. A strong longitudinal evaluation across programs allows the summative assessment of outcomes, an understanding of factors common to interventions that do and do not lead to success, and elucidates the processes developed for data collection and management. This will provide a framework for the assessment of other training programs and have national implications in transforming biomedical research training.

REACTOR PHYSICS QUARTERLY REPORT JANUARY, FEBRUARY, MARCH 1970

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmid, L. C.; Clayton, E. D.; Heineman, R. E.

1970-05-01

The objective of the Reactor Physics Quarterly Report is to inform the scientific community in a timely manner of the technical progress made on the many phases of reactor physics work within the laboratory. The report contains brief technical discussions of accomplishments in all areas where significant progress has been made during the quarter.

Boiler materials for ultra supercritical coal power plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Purgert, Robert; Shingledecker, John; Pschirer, James

2015-12-29

The U.S. Department of Energy (DOE) and the Ohio Coal Development Office (OCDO) have undertaken a project aimed at identifying, evaluating, and qualifying the materials needed for the construction of the critical components of coal-fired boilers capable of operating at much higher efficiencies than current generation of supercritical plants. This increased efficiency is expected to be achieved principally through the use of advanced ultrasupercritical (A-USC) steam conditions up to 760°C (1400°F) and 35 MPa (5000 psi). A limiting factor to achieving these higher temperatures and pressures for future A-USC plants are the materials of construction. The goal of this projectmore » is to assess/develop materials technology to build and operate an A-USC boiler capable of delivering steam with conditions up to 760°C (1400°F)/35 MPa (5000 psi). The project has successfully met this goal through a focused long-term public-private consortium partnership. The project was based on an R&D plan developed by the Electric Power Research Institute (EPRI) and an industry consortium that supplemented the recommendations of several DOE workshops on the subject of advanced materials. In view of the variety of skills and expertise required for the successful completion of the proposed work, a consortium led by the Energy Industries of Ohio (EIO) with cost-sharing participation of all the major domestic boiler manufacturers, ALSTOM Power (Alstom), Babcock and Wilcox Power Generation Group, Inc. (B&W), Foster Wheeler (FW), and Riley Power, Inc. (Riley), technical management by EPRI and research conducted by Oak Ridge National Laboratory (ORNL) has been developed. The project has clearly identified and tested materials that can withstand 760°C (1400°F) steam conditions and can also make a 700°C (1300°F) plant more economically attractive. In this project, the maximum temperature capabilities of these and other available high-temperature alloys have been assessed to provide a basis for materials selection and application under a range of conditions prevailing in the boiler. A major effort involving eight tasks was completed in Phase 1. In a subsequent Phase 2 extension, the earlier defined tasks were extended to finish and enhance the Phase 1 activities. This extension included efforts in improved weld/weldment performance, development of longer-term material property databases, additional field (in-plant) corrosion testing, improved understanding of long-term oxidation kinetics and exfoliation, cyclic operation, and fabrication methods for waterwalls. In addition, preliminary work was undertaken to model an oxyfuel boiler to define local environments expected to occur and to study corrosion behavior of alloys under these conditions. This final technical report provides a comprehensive summary of all the work undertaken by the consortium and the research findings from all eight (8) technical tasks including A-USC boiler design and economics (Task 1), long-term materials properties (Task 2), steam- side oxidation (Task 3), Fireside Corrosion (Task 4), Welding (Task 5), Fabricability (Task 6), Coatings (Task 7), and Design Data and Rules (Task 8).« less

Progress in the health and nutrition of girls in the Asia-Pacific region.

PubMed

Lee, Mi Kyung

2015-01-01

Since its inception 3 decades ago the Asia-Pacific Academic Consortium for Public Health (APACPH) has emphasized improving the health of disadvantaged and minority groups. In 1990, APACPH held a conference in Kathmandu with the theme, "The Girl Child in Asia: A Neglected Majority." Over the past 3 decades, the mortality rates for all children, particularly girls, have improved in our region. © 2014 APJPH.

George A. Olah, Carbocation and Hydrocarbon Chemistry

Science.gov Websites

. Final Technical Report. [HF:BF{sub 2}/H{sub 2}] , DOE Technical Report, 1980 Superacid Catalyzed Coal Conversion Chemistry. 1st and 2nd Quarterly Technical Progress Reports, September 1, 1983-March 30, 1984 , DOE Technical Report, 1984 Superacid Catalyzed Coal Conversion Chemistry. Final Technical Report

HKHC Community Dashboard: design, development, and function of a Web-based performance monitoring system.

PubMed

Bors, Philip A; Kemner, Allison; Fulton, John; Stachecki, Jessica; Brennan, Laura K

2015-01-01

As part of Robert Wood Johnson Foundation's Healthy Kids, Healthy Communities (HKHC) national grant program, a technical assistance team designed the HKHC Community Dashboard, an online progress documentation and networking system. The Dashboard was central to HKHC's multimethod program evaluation and became a communication interface for grantees and technical assistance providers. The Dashboard was designed through an iterative process of identifying needs and priorities; designing the user experience, technical development, and usability testing; and applying visual design. The system was created with an open-source content management system and support for building an online community of users. The site developer trained technical assistance providers at the national program office and evaluators, who subsequently trained all 49 grantees. Evaluators provided support for Dashboard users and populated the site with the bulk of its uploaded tools and resource documents. The system tracked progress through an interactive work plan template, regular documentation by local staff and partners, and data coding and analysis by the evaluation team. Other features included the ability to broadcast information to Dashboard users via e-mail, event calendars, discussion forums, private messaging, a resource clearinghouse, a technical assistance diary, and real-time progress reports. The average number of Dashboard posts was 694 per grantee during the grant period. Technical assistance providers and grantees uploaded a total of 1304 resource documents. The Dashboard functions with the highest grantee satisfaction were its interfaces for sharing and progress documentation. A majority of Dashboard users (69%) indicated a preference for continued access to the Dashboard's uploaded resource documents. The Dashboard was a useful and innovative tool for participatory evaluation of a large national grant program. While progress documentation added some burden to local project staff, the system proved to be a useful resource-sharing technology.

Consortium for Petroleum & Natural Gas Stripper Wells PART 3 OF 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morrison, Joel

The United States has more oil and gas wells than any other country. As of December 31, 2004, there were more than half a million producing oil wells in the United States. That is more than three times the combined total for the next three leaders: China, Canada, and Russia. The Stripper Well Consortium (SWC) is a partnership that includes domestic oil and gas producers, service and supply companies, trade associations, academia, the Department of Energy’s Strategic Center for Natural Gas and Oil (SCNGO) at the National Energy Technology Laboratory (NETL), and the New York State Energy Research and Developmentmore » Authority (NYSERDA). The Consortium was established in 2000. This report serves as a final technical report for the SWC activities conducted over the May 1, 2004 to December 1, 2011 timeframe. During this timeframe, the SWC worked with 173 members in 29 states and three international countries, to focus on the development of new technologies to benefit the U.S. stripper well industry. SWC worked with NETL to develop a nationwide request-for-proposal (RFP) process to solicit proposals from the U.S. stripper well industry to develop and/or deploy new technologies that would assist small producers in improving the production performance of their stripper well operations. SWC conducted eight rounds of funding. A total of 132 proposals were received. The proposals were compiled and distributed to an industrydriven SWC executive council and program sponsors for review. Applicants were required to make a formal technical presentation to the SWC membership, executive council, and program sponsors. After reviewing the proposals and listening to the presentations, the executive council made their funding recommendations to program sponsors. A total of 64 projects were selected for funding, of which 59 were fully completed. Penn State then worked with grant awardees to issue a subcontract for their approved work. SWC organized and hosted a total of 14 meetings dedicated to technology transfer to showcase and review SWC-funded technology. The workshops were open to the stripper well industry.« less

Consortium for Petroleum & Natural Gas Stripper Wells PART 2 OF 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morrison, Joel

2011-12-01

The United States has more oil and gas wells than any other country. As of December 31, 2004, there were more than half a million producing oil wells in the United States. That is more than three times the combined total for the next three leaders: China, Canada, and Russia. The Stripper Well Consortium (SWC) is a partnership that includes domestic oil and gas producers, service and supply companies, trade associations, academia, the Department of Energy’s Strategic Center for Natural Gas and Oil (SCNGO) at the National Energy Technology Laboratory (NETL), and the New York State Energy Research and Developmentmore » Authority (NYSERDA). The Consortium was established in 2000. This report serves as a final technical report for the SWC activities conducted over the May 1, 2004 to December 1, 2011 timeframe. During this timeframe, the SWC worked with 173 members in 29 states and three international countries, to focus on the development of new technologies to benefit the U.S. stripper well industry. SWC worked with NETL to develop a nationwide request-for-proposal (RFP) process to solicit proposals from the U.S. stripper well industry to develop and/or deploy new technologies that would assist small producers in improving the production performance of their stripper well operations. SWC conducted eight rounds of funding. A total of 132 proposals were received. The proposals were compiled and distributed to an industrydriven SWC executive council and program sponsors for review. Applicants were required to make a formal technical presentation to the SWC membership, executive council, and program sponsors. After reviewing the proposals and listening to the presentations, the executive council made their funding recommendations to program sponsors. A total of 64 projects were selected for funding, of which 59 were fully completed. Penn State then worked with grant awardees to issue a subcontract for their approved work. SWC organized and hosted a total of 14 meetings dedicated to technology transfer to showcase and review SWC-funded technology. The workshops were open to the stripper well industry.« less

Modeling the impacts of climate change and technical progress on the wheat yield in inland China: An autoregressive distributed lag approach.

PubMed

Zhai, Shiyan; Song, Genxin; Qin, Yaochen; Ye, Xinyue; Lee, Jay

2017-01-01

This study aims to evaluate the impacts of climate change and technical progress on the wheat yield per unit area from 1970 to 2014 in Henan, the largest agricultural province in China, using an autoregressive distributed lag approach. The bounded F-test for cointegration among the model variables yielded evidence of a long-run relationship among climate change, technical progress, and the wheat yield per unit area. In the long run, agricultural machinery and fertilizer use both had significantly positive impacts on the per unit area wheat yield. A 1% increase in the aggregate quantity of fertilizer use increased the wheat yield by 0.19%. Additionally, a 1% increase in machine use increased the wheat yield by 0.21%. In contrast, precipitation during the wheat growth period (from emergence to maturity, consisting of the period from last October to June) led to a decrease in the wheat yield per unit area. In the short run, the coefficient of the aggregate quantity of fertilizer used was negative. Land size had a significantly positive impact on the per unit area wheat yield in the short run. There was no significant short-run or long-run impact of temperature on the wheat yield per unit area in Henan Province. The results of our analysis suggest that climate change had a weak impact on the wheat yield, while technical progress played an important role in increasing the wheat yield per unit area. The results of this study have implications for national and local agriculture policies under climate change. To design well-targeted agriculture adaptation policies for the future and to reduce the adverse effects of climate change on the wheat yield, climate change and technical progress factors should be considered simultaneously. In addition, adaptive measures associated with technical progress should be given more attention.

Modeling the impacts of climate change and technical progress on the wheat yield in inland China: An autoregressive distributed lag approach

PubMed Central

Qin, Yaochen; Lee, Jay

2017-01-01

This study aims to evaluate the impacts of climate change and technical progress on the wheat yield per unit area from 1970 to 2014 in Henan, the largest agricultural province in China, using an autoregressive distributed lag approach. The bounded F-test for cointegration among the model variables yielded evidence of a long-run relationship among climate change, technical progress, and the wheat yield per unit area. In the long run, agricultural machinery and fertilizer use both had significantly positive impacts on the per unit area wheat yield. A 1% increase in the aggregate quantity of fertilizer use increased the wheat yield by 0.19%. Additionally, a 1% increase in machine use increased the wheat yield by 0.21%. In contrast, precipitation during the wheat growth period (from emergence to maturity, consisting of the period from last October to June) led to a decrease in the wheat yield per unit area. In the short run, the coefficient of the aggregate quantity of fertilizer used was negative. Land size had a significantly positive impact on the per unit area wheat yield in the short run. There was no significant short-run or long-run impact of temperature on the wheat yield per unit area in Henan Province. The results of our analysis suggest that climate change had a weak impact on the wheat yield, while technical progress played an important role in increasing the wheat yield per unit area. The results of this study have implications for national and local agriculture policies under climate change. To design well-targeted agriculture adaptation policies for the future and to reduce the adverse effects of climate change on the wheat yield, climate change and technical progress factors should be considered simultaneously. In addition, adaptive measures associated with technical progress should be given more attention. PMID:28950027

Supply Chain Sustainability Analysis of Whole Algae Hydrothermal Liquefaction and Upgrading

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pegallapati, Ambica Koushik; Dunn, Jennifer B.; Frank, Edward D.

2015-04-01

The Department of Energy's Bioenergy Technology Office (BETO) collaborates with a wide range of institutions towards the development and deployment of biofuels and bioproducts. To facilitate this effort, BETO and its partner national laboratories develop detailed techno-economic assessments (TEA) of biofuel production technologies as part of the development of design cases and state of technology (SOT) analyses. A design case is a TEA that outlines a target case for a particular biofuel pathway. It enables preliminary identification of data gaps and research and development needs and provides goals and targets against which technology progress is assessed. On the other hand,more » an SOT analysis assesses progress within and across relevant technology areas based on actual experimental results relative to technical targets and cost goals from design cases and includes technical, economic, and environmental criteria as available. (SOT) analyses. A design case is a TEA that outlines a target case for a particular biofuel pathway. It enables preliminary identification of data gaps and research and development needs and provides goals and targets against which technology progress is assessed. On the other hand, an SOT analysis assesses progress within and across relevant technology areas based on actual experimental results relative to technical targets and cost goals from design cases and includes technical, economic, and environmental criteria as available. (SOT) analyses. A design case is a TEA that outlines a target case for a particular biofuel pathway. It enables preliminary identification of data gaps and research and development needs and provides goals and targets against which technology progress is assessed. On the other hand, an SOT analysis assesses progress within and across relevant technology areas based on actual experimental results relative to technical targets and cost goals from design cases and includes technical, economic, and environmental criteria as available.« less

CUBN Is a Gene Locus for Albuminuria

PubMed Central

Böger, Carsten A.; Chen, Ming-Huei; Tin, Adrienne; Olden, Matthias; Köttgen, Anna; de Boer, Ian H.; Fuchsberger, Christian; O'Seaghdha, Conall M.; Pattaro, Cristian; Teumer, Alexander; Liu, Ching-Ti; Glazer, Nicole L.; Li, Man; O'Connell, Jeffrey R.; Tanaka, Toshiko; Peralta, Carmen A.; Kutalik, Zoltán; Luan, Jian'an; Zhao, Jing Hua; Hwang, Shih-Jen; Akylbekova, Ermeg; Kramer, Holly; van der Harst, Pim; Smith, Albert V.; Lohman, Kurt; de Andrade, Mariza; Hayward, Caroline; Kollerits, Barbara; Tönjes, Anke; Aspelund, Thor; Ingelsson, Erik; Eiriksdottir, Gudny; Launer, Lenore J.; Harris, Tamara B.; Shuldiner, Alan R.; Mitchell, Braxton D.; Arking, Dan E.; Franceschini, Nora; Boerwinkle, Eric; Egan, Josephine; Hernandez, Dena; Reilly, Muredach; Townsend, Raymond R.; Lumley, Thomas; Siscovick, David S.; Psaty, Bruce M.; Kestenbaum, Bryan; Haritunians, Talin; Bergmann, Sven; Vollenweider, Peter; Waeber, Gerard; Mooser, Vincent; Waterworth, Dawn; Johnson, Andrew D.; Florez, Jose C.; Meigs, James B.; Lu, Xiaoning; Turner, Stephen T.; Atkinson, Elizabeth J.; Leak, Tennille S.; Aasarød, Knut; Skorpen, Frank; Syvänen, Ann-Christine; Illig, Thomas; Baumert, Jens; Koenig, Wolfgang; Krämer, Bernhard K.; Devuyst, Olivier; Mychaleckyj, Josyf C.; Minelli, Cosetta; Bakker, Stephan J.L.; Kedenko, Lyudmyla; Paulweber, Bernhard; Coassin, Stefan; Endlich, Karlhans; Kroemer, Heyo K.; Biffar, Reiner; Stracke, Sylvia; Völzke, Henry; Stumvoll, Michael; Mägi, Reedik; Campbell, Harry; Vitart, Veronique; Hastie, Nicholas D.; Gudnason, Vilmundur; Kardia, Sharon L.R.; Liu, Yongmei; Polasek, Ozren; Curhan, Gary; Kronenberg, Florian; Prokopenko, Inga; Rudan, Igor; Ärnlöv, Johan; Hallan, Stein; Navis, Gerjan; Parsa, Afshin; Ferrucci, Luigi; Coresh, Josef; Shlipak, Michael G.; Bull, Shelley B.; Paterson, Andrew D.; Wichmann, H.-Erich; Wareham, Nicholas J.; Loos, Ruth J.F.; Rotter, Jerome I.; Pramstaller, Peter P.; Cupples, L. Adrienne; Beckmann, Jacques S.; Yang, Qiong; Heid, Iris M.; Rettig, Rainer; Dreisbach, Albert W.; Bochud, Murielle

2011-01-01

Identification of genetic risk factors for albuminuria may alter strategies for early prevention of CKD progression, particularly among patients with diabetes. Little is known about the influence of common genetic variants on albuminuria in both general and diabetic populations. We performed a meta-analysis of data from 63,153 individuals of European ancestry with genotype information from genome-wide association studies (CKDGen Consortium) and from a large candidate gene study (CARe Consortium) to identify susceptibility loci for the quantitative trait urinary albumin-to-creatinine ratio (UACR) and the clinical diagnosis microalbuminuria. We identified an association between a missense variant (I2984V) in the CUBN gene, which encodes cubilin, and both UACR (P = 1.1 × 10−11) and microalbuminuria (P = 0.001). We observed similar associations among 6981 African Americans in the CARe Consortium. The associations between this variant and both UACR and microalbuminuria were significant in individuals of European ancestry regardless of diabetes status. Finally, this variant associated with a 41% increased risk for the development of persistent microalbuminuria during 20 years of follow-up among 1304 participants with type 1 diabetes in the prospective DCCT/EDIC Study. In summary, we identified a missense CUBN variant that associates with levels of albuminuria in both the general population and in individuals with diabetes. PMID:21355061

TIMES-SS--recent refinements resulting from an industrial skin sensitisation consortium.

PubMed

Patlewicz, G; Kuseva, C; Mehmed, A; Popova, Y; Dimitrova, G; Ellis, G; Hunziker, R; Kern, P; Low, L; Ringeissen, S; Roberts, D W; Mekenyan, O

2014-01-01

The TImes MEtabolism Simulator platform for predicting Skin Sensitisation (TIMES-SS) is a hybrid expert system, first developed at Bourgas University using funding and data from a consortium of industry and regulators. TIMES-SS encodes structure-toxicity and structure-skin metabolism relationships through a number of transformations, some of which are underpinned by mechanistic 3D QSARs. The model estimates semi-quantitative skin sensitisation potency classes and has been developed with the aim of minimising animal testing, and also to be scientifically valid in accordance with the OECD principles for (Q)SAR validation. In 2007 an external validation exercise was undertaken to fully address these principles. In 2010, a new industry consortium was established to coordinate research efforts in three specific areas: refinement of abiotic reactions in the skin (namely autoxidation) in the skin, refinement of the manner in which chemical reactivity was captured in terms of structure-toxicity rules (inclusion of alert reliability parameters) and defining the domain based on the underlying experimental data (study of discrepancies between local lymph node assay Local Lymph Node Assay (LLNA) and Guinea Pig Maximisation Test (GPMT)). The present paper summarises the progress of these activities and explains how the insights derived have been translated into refinements, resulting in increased confidence and transparency in the robustness of the TIMES-SS predictions.

Technical Adequacy of Growth Estimates from a Computer Adaptive Test: Implications for Progress Monitoring

ERIC Educational Resources Information Center

Van Norman, Ethan R.; Nelson, Peter M.; Parker, David C.

2017-01-01

Computer adaptive tests (CATs) hold promise to monitor student progress within multitiered systems of support. However, the relationship between how long and how often data are collected and the technical adequacy of growth estimates from CATs has not been explored. Given CAT administration times, it is important to identify optimal data…

Education, Industrialization and Technical Progress in Mexico. IIEP Research Report No. 6.

ERIC Educational Resources Information Center

Padua, Jorge

This report attempts to analyze the contributions of the educational system and job training programs to industrialization and technical progress in the Conubal zone of the Lower Balsas River of Mexico. The first of the study's three sections consists of two chapters that provide general background. Chapter 1, "Theories of Development and the…

Technical Adequacy and Acceptability of Curriculum-Based Measurement and the Measures of Academic Progress

ERIC Educational Resources Information Center

January, Stacy-Ann A.; Ardoin, Scott P.

2015-01-01

Curriculum-based measurement in reading (CBM-R) and the Measures of Academic Progress (MAP) are assessment tools widely employed for universal screening in schools. Although a large body of research supports the validity of CBM-R, limited empirical evidence exists supporting the technical adequacy of MAP or the acceptability of either measure for…

Annual Technical Progress Report for Emergency School Assistance Program, Title 45, 1970-71.

ERIC Educational Resources Information Center

Lindsey, Randall B.

This paper presents a technical progress report of two programs conducted with funds provided under the Emergency School Assistance Program. One, the Mobile Learning Unit, said to have been designed to measure changes in fourth and fifth grade students' self-concept in a reorganized desegregated school environment, focuses on whether a positive…

A PSFI-based analysis on the energy efficiency potential of China’s domestic passenger vehicles

NASA Astrophysics Data System (ADS)

Chen, Chuan; Ren, Huanhuan; Zhao, Dongchang

2017-01-01

In this article, China’s domestic passenger vehicles (excluding new energy vehicles) are categorized into two groups: local brand vehicles and vehicles manufactured by joint ventures. Performance-Size-Fuel economy Index (PSFI) will be applied to analyse the speed of technical progress and the future trends of these vehicles. In addition, a forecast on energy efficiency potential of domestic passenger vehicles from 2016 to 2020 will be made based on different Emphasis on Reducing Fuel Consumption (ERFC) scenarios. According to the study, if the process of technical progress continues at its current speed, domestic ICE passenger vehicles will hardly meet Phase IV requirements by 2020 even though companies contribute as much technical progress to fuel consumption reduction as possible.

Advanced Thermal Emission Imaging Systems Definition and Development

NASA Technical Reports Server (NTRS)

Blasius, Karl; Nava, David (Technical Monitor)

2002-01-01

Santa Barbara Remote Sensing (SBRS), Raytheon Company, is pleased to submit this quarterly progress report of the work performed in the third quarter of Year 2 of the Advanced THEMIS Project, July through September 2002. We review here progress in the proposed tasks. During July through September 2002 progress was made in two major tasks, Spectral Response Characterization and Flight Instrument Definition. Because of staffing problems and technical problems earlier in the program we have refocused the remaining time and budget on the key technical tasks. Current technical problems with a central piece of test equipment has lead us to request a 1 quarter extension to the period of performance. This request is being made through a separate letter independent of this report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stout, D.K.

Flaws are noted in equilibrium growth models which ignore the facts that labor is no longer homogeneous, national governments can no longer guarantee a managed demand, and technical progress is not an independent force. The pace of technical progress is the major variable and increases with competition and certainty in the growth of demand. The outlook for technical progress is examined in the context of productivity, using microprocessor development for illustration. The author takes an optimistic view of new developments in that they do not bring the self-destructive possibility of overpopulation, irreversible damage to the environment, or nuclear war anymore » closer, while having a positive chance to promote a more rewarding relationship between education, work, and life style. The opportunities for positive humanistic changes through microprocessing are confirmed. (DCK)« less

Index to Nuclear Safety. A technical progress review by chronology, permuted title, and author. Vol. 11, No. 1--Vol. 17, No. 6

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cottrell, W.B.; Klein, A.

1977-02-23

This index to Nuclear Safety covers articles in Nuclear Safety Vol. 11, No. 1 (Jan.-Feb. 1970), through Vol. 17, No. 6 (Nov.-Dec. 1976). The index includes a chronological list of articles (including abstract) followed by KWIC and Author Indexes. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. The index lists over 350 technical articles in the last six years of publication.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paul Higley; J. Robert Woolsey; Ralph Goodman

A Consortium, designed to assemble leaders in gas hydrates research, has been established at the University of Mississippi's Center for Marine Resources and Environmental Technology, CMRET. The primary objective of the group is to design and emplace a remote monitoring station on the sea floor in the northern Gulf of Mexico by the year 2005, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission necessitates assembling a station that will monitor physical and chemical parameters of the sea water and sea floor sediments on a more-or-less continuous basis overmore » an extended period of time. Development of the station allows for the possibility of expanding its capabilities to include biological monitoring, as a means of assessing environmental health. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in this relatively new research arena. Complementary expertise, both scientific and technical, has been assembled to promote innovative research methods and construct necessary instrumentation. Noteworthy achievements one year into the extended life of this cooperative agreement include: (1) Progress on the vertical line array (VLA) of sensors: (1a) Repair attempts of the VLA cable damaged in the October >1000m water depth deployment failed; a new design has been tested successfully. (1b) The acoustic modem damaged in the October deployment was repaired successfully. (1c) Additional acoustic modems with greater depth rating and the appropriate surface communications units have been purchased. (1d) The VLA computer system is being modified for real time communications to the surface vessel using radio telemetry and fiber optic cable. (1e) Positioning sensors--including compass and tilt sensors--were completed and tested. (1f) One of the VLAs has been redesigned to collect near sea floor geochemical data. (2) Progress on the Sea Floor Probe: (2a) With the Consortium's decision to divorce its activities from those of the Joint Industries Program (JIP), due to the JIP's selection of a site in 1300m of water, the Sea Floor Probe (SFP) system was revived as a means to emplace arrays in the shallow subsurface until arrangements can be made for boreholes at >1000m water depth. (2b) The SFP penetrometer has been designed and construction begun. (2c) The SFP geophysical and pore-fluid probes have been designed. (3) Progress on the Acoustic Systems for Monitoring Gas Hydrates: (3a) Video recordings of bubbles emitted from a seep in Mississippi Canyon have been analyzed for effects of currents and temperature changes. (3b) Several acoustic monitoring system concepts have been evaluated for their appropriateness to MC118, i.e., on the deep sea floor. (3c) A mock-up system was built but was rejected as too impractical for deployment on the sea floor. (4) Progress on the Electromagnetic Bubble Detector and Counter: (4a) Laboratory tests were performed using bubbles of different sizes in waters of different salinities to test the sensitivity of the. Differences were detected satisfactorily. (4b) The system was field tested, first at the dock and then at the shallow water test site at Cape Lookout Bight where methane bubbles from the sea floor, naturally, in 10m water depth. The system successfully detected peaks in bubbling as spike decreases in conductivity. (5) Progress on the Mid-Infrared Sensor for Continuous Methane Monitoring: (5a) Modeling and design of an optics platform complementary to the constructed electronics platform for successful incorporation into ''sphereIR'' continues. AutoCAD design and manual construction of mounting pieces for major optical components have been completed. (5b) Initial design concepts for IR-ATR sensor probe geometries have been established and evaluated. Initial evaluations of a horizontal ATR (HATR) sensing probe with fiber optic guiding light have been performed and validate the design concept as a potentially viable deep sea sensing probe. (5c) Ray tracing simulations have been performed to evaluate light propagation through HATR elements to facilitate the optimal design of both the sensing probe and optical configuration of ''sphereIR''. (5d) The highly permeable polymer, polydimethylsiloxane (PDMS), was investigated as a potential methane enrichment membrane for IR-ATR sensors. (6) Progress on the Seismo-acoustic Characterization of Sea Floor Properties and Processes at the Hydrate Monitoring Station: (6a) All system components underwent extensive testing in preparation for determining sea floor acoustic reflection responses at the Gas Hydrate Monitoring Station. (6b) Final testing and commissioning have been completed.« less

The Mustard Consortium’s Elucidation of the Pathophysiology of Sulfur Mustard and Antidote Development

DTIC Science & Technology

2006-09-01

these tissues. There was essentially no change in the tocopherol levels. These results imply that CEES produces systemic oxidative stress at a...of CEES-induced acute lung injury, even though little is currently known about how CEES produces acute and progressive lung injury. Body...Medical School). 3. Pulmonary clearance of Pseudomonas aeruginosa in CEES treated rats. It is not known if exposure to CEES compromises the ability

Commercialization and internationalization of the next-generation launch system

NASA Astrophysics Data System (ADS)

Bille, Matthew A.; Richie, George E.; Bille, Deborah A.

1996-03-01

The United States, ESA, Russia, and Japan are all pursuing the goal of a next-generation launch system. However, economic constraints may ground these programs, as they did hypersonic spaceplane efforts. In today's constrained fiscal environment, engineering is secondary unless the most practical economic and political approach is also found. While international efforts face national concerns over jobs and competitiveness, low-cost access to orbit will open up space to whole new industries. In the long run, all involved nations will gain economically if a next-generation launcher is built, and all will lose if individual efforts fail. An international consortium is most likely to amass the resources needed. The consortium would not be dedicated to any single technical concept, but would select from industry proposals to design and build the technology demonstrator. The goal is to get one working system built: after that, it is not critical whether we have one cooperative operational system or a dozen competing ones. What is critical is not to miss another chance to launch the era of space commercialization.

Recommended Implementation of Arterial Spin Labeled Perfusion MRI for Clinical Applications: A consensus of the ISMRM Perfusion Study Group and the European Consortium for ASL in Dementia

PubMed Central

Alsop, David C.; Detre, John A.; Golay, Xavier; Günther, Matthias; Hendrikse, Jeroen; Hernandez-Garcia, Luis; Lu, Hanzhang; MacIntosh, Bradley J.; Parkes, Laura M.; Smits, Marion; van Osch, Matthias J. P.; Wang, Danny JJ; Wong, Eric C.; Zaharchuk, Greg

2014-01-01

This article provides a summary statement of recommended implementations of arterial spin labeling (ASL) for clinical applications. It is a consensus of the ISMRM Perfusion Study Group and the European ‘ASL in Dementia’ consortium, both of whom met to reach this consensus in October 2012 in Amsterdam. Although ASL continues to undergo rapid technical development, we believe that current ASL methods are robust and ready to provide useful clinical information, and that a consensus statement on recommended implementations will help the clinical community to adopt a standardized approach. In this article we describe the major considerations and tradeoffs in implementing an ASL protocol, and provide specific recommendations for a standard approach. Our conclusions are that, as an optimal default implementation we recommend: pseudo-continuous labeling, background suppression, a segmented 3D readout without vascular crushing gradients, and calculation and presentation of both label/control difference images and cerebral blood flow in absolute units using a simplified model. PMID:24715426

Methodological synergies for glaciological constraints to find Oldest Ice

NASA Astrophysics Data System (ADS)

Eisen, Olaf

2017-04-01

The Beyond EPICA - Oldest Ice (BE-OI) consortium and its international partners unite a globally unique concentration of scientific expertise and infrastructure for ice-core investigations. It delivers the technical, scientific and financial basis for a comprehensive plan to retrieve an ice core up to 1.5 million years old. The consortium takes care of the pre-site surveys for site selection around Dome C and Dome Fuji, both potentially appropriate regions in East Antarctica. Other science consortia will investigate other regions under the umbrella of the International Partnerships in Ice Core Sciences (IPICS). Of major importance to obtain reliable estimates of the age of the ice in the basal layers of the ice sheet are the physical boundary conditions and ice-flow dynamics: geothermal heat flux, advection and layer integrity to avoid layer overturning and the formation of folds. The project completed the first field season at both regions of interest. This contribution will give an overview how the combined application of various geophysical, geodetical and glaciological methods applied in the field in combination with ice-flow modelling can constrain the glaciological boundary conditions and thus age at depth.

SEEA SOUTHEAST CONSORTIUM FINAL TECHNICAL REPORT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Block, Timothy; Ball, Kia; Fournier, Ashley

In 2010 the Southeast Energy Efficiency Alliance (SEEA) received a $20 million Energy Efficiency and Conservation Block Grant (EECBG) under the U.S. Department of Energy’s Better Building Neighborhood Program (BBNP). This grant, funded by the American Recovery and Reinvestment Act, also included sub-grantees in 13 communities across the Southeast, known as the Southeast Consortium. The objective of this project was to establish a framework for energy efficiency retrofit programs to create models for replication across the Southeast and beyond. To achieve this goal, SEEA and its project partners focused on establishing infrastructure to develop and sustain the energy efficiency marketmore » in specific localities across the southeast. Activities included implementing minimum training standards and credentials for marketplace suppliers, educating and engaging homeowners on the benefits of energy efficiency through strategic marketing and outreach and addressing real or perceived financial barriers to investments in whole-home energy efficiency through a variety of financing mechanisms. The anticipated outcome of these activities would be best practice models for program design, marketing, financing, data collection and evaluation as well as increased market demand for energy efficiency retrofits and products. The Southeast Consortium’s programmatic impacts along with the impacts of the other BBNP grantees would further the progress towards the overall goal of energy efficiency market transformation. As the primary grantee SEEA served as the overall program administrator and provided common resources to the 13 Southeast Consortium sub-grantees including contracted services for contractor training, quality assurance testing, data collection, reporting and compliance. Sub-grantee programs were located in cities across eight states including Alabama, Florida, Georgia, Louisiana, North Carolina, South Carolina, Tennessee, Virginia and the U.S. Virgin Islands. Each sub-grantee program was designed to address the unique local conditions and population of its community. There was great diversity in programs design, types of financing and incentives, building stock characteristics, climate and partnerships. From 2010 through 2013, SEEA and its sub-grantee programs focused on determining best practices in program administration, workforce development, marketing and consumer education, financing, and utility partnerships. One of the common themes among programs that were most successful in each of these areas was strong partnerships and collaborations with people or organizations in the community. In many instances engaged partners proved to be the key to addressing barriers such as access to financing, workforce development opportunities and access to utility bill data. The most challenging barrier proved to be the act of building a market for energy efficiency where none previously existed. With limited time and resources, educating homeowners of the value in investing in energy efficiency while engaging electric and gas utilities served as a significant barrier for several programs. While there is still much work to be done to continue to transform the energy efficiency market in the Southeast, the programmatic activities led by SEEA and its sub-grantees resulted in 8,180 energy audits and 5,155 energy efficiency retrofits across the Southeast. In total the Southeast Consortium saved an estimated 27,915,655.93 kWh and generated an estimated $ 2,291,965.90 in annual energy cost savings in the region.« less

[Address Given at the Regional Junior College Recreation Education Institute, American River College, September 25, 1969.

ERIC Educational Resources Information Center

Lutzin, Sidney G.

The United States has made striking technical advances in recent years, but there has not been comparable progress in social services. Greater affluence and leisure for some have been one result of technical progress, but problems of poverty and urban development are more pressing. New developments to improve the condition of society can be…

THE DEVELOPMENT OF PRE-VOCATIONAL EDUCATION LITERACY COURSES FOR USE WITH COMPUTER ASSISTED INSTRUCTION OF DISADVANTAGED YOUTH AND ADULTS. TECHNICAL PROGRESS REPORT.

ERIC Educational Resources Information Center

HANKIN, EDWARD K.; AND OTHERS

THIS TECHNICAL PROGRESS REPORT COVERS THE FIRST THREE MONTHS OF A PROJECT TO DEVELOP COMPUTER ASSISTED PREVOCATIONAL READING AND ARITHMETIC COURSES FOR DISADVANTAGED YOUTHS AND ADULTS. DURING THE FIRST MONTH OF OPERATION, PROJECT PERSONNEL CONCENTRATED ON SUCH ADMINISTRATIVE MATTERS AS TRAINING STAFF AND PREPARING FACILITIES. AN ARITHMETIC PROGRAM…

Generation and focusing of pulsed intense ion beams. Technical progress report, 20 August 1981-30 September 1982

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hammer, D.A.; Kusse, B.R.; Sudan, R.N.

1983-07-01

The progress on this contract is described in two parts. The first deals with the technical operation of the LION accelerator which is the exact equivalent to one line of PBFA-I. The second part is concerned with the experimental results on the ion diode mounted at the front end of the LION accelerator.

Project LIFE--Language Improvement to Facilitate Education. (Technical Progress Report; Third Quarter; March 1, 1974-May 31, 1974).

ERIC Educational Resources Information Center

National Foundation for the Improvement of Education, Washington, DC.

Reported is the third quarter, fiscal year 1974 (March 1, 1974-May 31, 1974) technical progress of Project LIFE (Language Improvement to Facilitate Education), toward developing an instructional system in which filmstrips in the areas of perceptual training, perceptual thinking, and language/reading are used to assist hearing impaired children in…

Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 4

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ulm, Franz-Josef

2000-06-30

OAK-B135 Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 4. The analysis of the effect of cracks on the acceleration of the calcium leaching process of cement-based materials has been pursued. During the last period (Technical Progress Report No 3), we have introduced a modeling accounting for the high diffusivity of fractures in comparison with the weak solid material diffusivity. It has been shown through dimensional and asymptotic analysis that small fractures do not significantly accelerate the material aging process. This important result for the overall structural aging kinetics of containment structure has beenmore » developed in a paper submitted to the international journal ''Transport in Porous Media''.« less

A Brief Literature Overview of Various Routes to Biorenewable Fuels from Lipids for the National Alliance for Advanced Biofuels and Bio-products (NAABB) Consortium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Albrecht, Karl O.; Hallen, Richard T.

2011-03-29

Renewable methods of producing transportation fuels are currently the focus of numerous large research efforts across the globe. Renewable fuel produced from algal lipids is one aspect of this research that could have profound implications on future transportation fuel requirements. However, technical challenges remain in several areas of algal-lipid-based fuels. These challenges include the identification and development of robust and productive algal species as well as extraction methods to recover the produced lipids. Not the least of these technical challenges is the conversion of the algae lipids to fungible fuels. This brief literature review focuses primarily on state-of-the-art “downstream” applicationsmore » of producing fuel from fats and lipids, which can be applied to ongoing research with algae-derived lipids.« less

The Oman-India gas pipeline

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, P.M.

1995-12-31

In March 1993, the Governments of the Sultanate of Oman and India executed a Memorandum of Understanding for a long term Gas Supply Contract to transport natural gas from Oman to India by pipeline. A feasibility study was undertaken to determine if such a pipeline was technically achievable and economically attractive. Work was initiated with a consortium of internationally recognized major design and construction firms, as well as with consultants knowledgeable in gas supply and demand in the region. Alternative gas supply volumes as well as two distinct pipeline routes were analyzed in significant detail. As a result of thismore » work, it was concluded that a pipeline crossing, taking a direct route from Oman to India, is economically and technically feasible. In September, 1994, the Agreement on Principal Terms for supply of gas to India from Oman was agreed by the respective governmental authorities. The project and its status are described.« less

Role and goals of the EUR-OCEANS Consortium - Bringing marine scientists priorities and strategies to the European research planning agenda.

NASA Astrophysics Data System (ADS)

Cury, Philippe; Baisnée, Pierre-François

2010-05-01

The EUR-OCEANS Consortium is the follow-up structure of the homonym European Network of Excellence (NoE; 2005-2008, FP6 contract number 511106). It is a scientific network, benefiting from and relying upon the institutional commitment of the 27 research performing organisations forming its core (paying) membership. It aims at the long-term harmonization of European research efforts related to ocean ecosystems undergoing anthropogenic and natural forcing. More specifically, its objectives are to facilitate and promote: (1) top-level scientific research on the impacts of anthropogenic and natural forcing on ocean ecosystems, fostering collaborations across the European Research Area; (2) the optimal use of any shared technical infrastructures and scientific facilities; and (3) activities to spread excellence, such as the training of scientific personnel and students, or knowledge dissemination towards the general public and socio-economic users. A particular focus is put during the first scientific coordination mandate on the building of scenarios for marine ecosystems under anthropogenic and natural forcing in the XXI Century, and on the improvement of the science-policy interface. Through calls for projects and networking activities, the Consortium seeks to favour the emergence of coordinated projects on key hot topics on one hand, and the crystallisation of scientific priorities and strategies that could serve as input to ERA-NETs, ESFRI, Joint Programming Initiatives and European Research Planning actors in general. While being an active standalone structure, the Consortium is also engaged in the Euromarine FP7 project (submitted) aiming at the definition of a common coordinating or integrating structure for the three follow-up entities of FP6 marine science NoEs (Marine Genomics Europe, MarBEF, EUR-OCEANS). The 2009-2011 strategy and activity plan of EUR-OCEANS will be presented and the involvement of EUR-OCEANS members in other key projects or programmes will be summarized.

Educating and Training a Workforce for Nutrition in a Post-2015 World12

PubMed Central

Fanzo, Jessica C; Graziose, Matthew M; Kraemer, Klaus; Gillespie, Stuart; Johnston, Jessica L; de Pee, Saskia; Monterrosa, Eva; Badham, Jane; Bloem, Martin W; Dangour, Alan D; Deckelbaum, Richard; Dobermann, Achim; Fracassi, Patrizia; Hossain, SM Moazzem; Ingram, John; Jerling, Johann C; Jones, CJ; Jap, Stefanus Indrayana; Kiess, Lynnda; Marshall, Quinn; Martin, Keith; Narayan, Anuradha; Amuyunzu-Nayamongo, Mary; Pepping, Fré; West, Keith P

2015-01-01

Nearly all countries in the world today are burdened with malnutrition, manifesting as undernutrition, micronutrient deficiencies, and/or overweight and obesity. Despite some progress, efforts to alleviate malnutrition are hampered by a shortage in number, skills, and geographic coverage, of a workforce for nutrition. Here, we report the findings of the Castel Gandolfo workshop, a convening of experts from diverse fields in March 2014 to consider how to develop the capacity of a global cadre of nutrition professionals for the post-2015 development era. Workshop participants identified several requirements for developing a workforce for nutrition, including an ability to work as part of a multisectoral team; communication, advocacy, and leadership skills to engage decision makers; and a set of technical skills to address future challenges for nutrition. Other opportunities were highlighted that could immediately contribute to capacity development, including the creation of a consortium to link global North and South universities, online training modules for middle managers, and practical, hands-on experiences for frontline nutrition workers. Institutional and organizational support is needed to enable workshop recommendations on education and training to be effectively implemented and sustained. The findings from the Castel Gandolfo workshop can contribute to the delivery of successful nutrition-relevant actions in the face of mounting external pressures and informing and attaining the forthcoming Sustainable Development Goals. PMID:26567189

Educating and training a workforce for nutrition in a post-2015 world.

PubMed

Fanzo, Jessica C; Graziose, Matthew M; Kraemer, Klaus; Gillespie, Stuart; Johnston, Jessica L; de Pee, Saskia; Monterrosa, Eva; Badham, Jane; Bloem, Martin W; Dangour, Alan D; Deckelbaum, Richard; Dobermann, Achim; Fracassi, Patrizia; Hossain, Sm Moazzem; Ingram, John; Jerling, Johann C; Jones, C J; Jap, Stefanus Indrayana; Kiess, Lynnda; Marshall, Quinn; Martin, Keith; Narayan, Anuradha; Amuyunzu-Nayamongo, Mary; Pepping, Fré; West, Keith P

2015-11-01

Nearly all countries in the world today are burdened with malnutrition, manifesting as undernutrition, micronutrient deficiencies, and/or overweight and obesity. Despite some progress, efforts to alleviate malnutrition are hampered by a shortage in number, skills, and geographic coverage, of a workforce for nutrition. Here, we report the findings of the Castel Gandolfo workshop, a convening of experts from diverse fields in March 2014 to consider how to develop the capacity of a global cadre of nutrition professionals for the post-2015 development era. Workshop participants identified several requirements for developing a workforce for nutrition, including an ability to work as part of a multisectoral team; communication, advocacy, and leadership skills to engage decision makers; and a set of technical skills to address future challenges for nutrition. Other opportunities were highlighted that could immediately contribute to capacity development, including the creation of a consortium to link global North and South universities, online training modules for middle managers, and practical, hands-on experiences for frontline nutrition workers. Institutional and organizational support is needed to enable workshop recommendations on education and training to be effectively implemented and sustained. The findings from the Castel Gandolfo workshop can contribute to the delivery of successful nutrition-relevant actions in the face of mounting external pressures and informing and attaining the forthcoming Sustainable Development Goals. © 2015 American Society for Nutrition.

Improving Undergraduate Research Experiences With An Intentional Mentoring Program: Lessons Learned Through Assessment of Keck Geology Consortium Programs

NASA Astrophysics Data System (ADS)

Wirth, K. R.; Garver, J. I.; Greer, L.; Pollock, M.; Varga, R. J.; Davidson, C. M.; Frey, H. M.; Hubbard, D. K.; Peck, W. H.; Wobus, R. A.

2015-12-01

The Keck Geology Consortium, with support from the National Science Foundation (REU Program) and ExxonMobil, is a collaborative effort by 18 colleges to improve geoscience education through high-quality research experiences. Since its inception in 1987 more than 1350 undergraduate students and 145 faculty have been involved in 189 yearlong research projects. This non-traditional REU model offers exceptional opportunities for students to address research questions at a deep level, to learn and utilize sophisticated analytical methods, and to engage in authentic collaborative research that culminates in an undergraduate research symposium and published abstracts volume. The large numbers of student and faculty participants in Keck projects also affords a unique opportunity to study the impacts of program design on undergraduate research experiences in the geosciences. Students who participate in Keck projects generally report significant gains in personal and professional dimensions, as well as in clarification of educational and career goals. Survey data from student participants, project directors, and campus advisors identify mentoring as one of the most critical and challenging elements of successful undergraduate research experiences. Additional challenges arise from the distributed nature of Keck projects (i.e., participants, project directors, advisors, and other collaborators are at different institutions) and across the span of yearlong projects. In an endeavor to improve student learning about the nature and process of science, and to make mentoring practices more intentional, the Consortium has developed workshops and materials to support both project directors and campus research advisors (e.g., best practices for mentoring, teaching ethical professional conduct, benchmarks for progress, activities to support students during research process). The Consortium continues to evolve its practices to better support students from underrepresented groups.

Consortium for materials development in space interaction with Space Station Freedom

NASA Technical Reports Server (NTRS)

Lundquist, Charles A.; Seaquist, Valerie

1992-01-01

The Consortium for Materials Development in Space (CMDS) is one of seventeen Centers for the Commercial Development of Space (CCDS) sponsored by the Office of Commercial Programs of NASA. The CMDS formed at the University of Alabama in Huntsville in the fall of 1985. The Consortium activities therefore will have progressed for over a decade by the time Space Station Freedom (SSF) begins operation. The topic to be addressed here is: what are the natural, mutually productive relationships between the CMDS and SSF? For management and planning purposes, the Consortium organizes its activities into a number of individual projects. Normally, each project has a team of personnel from industry, university, and often government organizations. This is true for both product-oriented materials projects and for infrastructure projects. For various projects Space Station offers specific mutually productive relationships. First, SSF can provide a site for commercial operations that have evolved as a natural stage in the life cycle of individual projects. Efficiency and associated cost control lead to another important option. With SSF in place, there is the possibility to leave major parts of processing equipment in SSF, and only bring materials to SSF to be processed and return to earth the treated materials. This saves the transportation costs of repeatedly carrying heavy equipment to orbit and back to the ground. Another generic feature of commercial viability can be the general need to accomplish large through-put or large scale operations. The size of SSF lends itself to such needs. Also in addition to processing equipment, some of the other infrastructure capabilities developed in CCDS projects may be applied on SSF to support product activities. The larger SSF program may derive mutual benefits from these infrastructure abilities.

Round table discussion " Development of qualification framework in meteorology (TEMPUS QUALIMET)"

NASA Astrophysics Data System (ADS)

Bashmakova, I.; Belotserkovsky, A.; Karlin, L.; Petrosyan, A.; Serditova, N.; Zilitinkevich, S.

2010-09-01

The international consortium has started implementing a project aimed at the development of unified framework of qualifications in meteorology (QualiMet), setting a system of recognition and award of qualifications up to Doctoral level based on standards of knowledge, skill and competence acquired by learners is underway. The QualiMet has the following specific objectives: 1. To develop standards of knowledge, skills and competence for all qualifications up to Doctoral level needed in all possible occupations meteorology learner can undertake, by July 2011 2. To develop reciprocally recognized rubrics, criteria, methods and tools for assessing the compliance with the developed standards (quality assurance), by July 2012 3. To set the network of Centers of Excellence as the primary designer of sample education programs and learning experiences, both in brick-and-mortar and distant setting of delivery, leading to achievement of the developed standards, by December 2012 4. To set a system of mutual international recognition and award of qualifications in meteorology based on the developed procedures and establishment of self-regulatory public organization, by December 2012 The main beneficiaries of the project are: 1. Meteorology learners from the consortium countries. They will be able to make informed decisions about available qualification choices and progression options and provided an opportunity for students and graduates to participate in the system of international continuous education. 2. Meteorology employers from the consortium countries, They will be able to specify the level of knowledge, skill and competence required for occupational roles, evaluate qualifications presented, connect training and development with business needs. 3. Students and academic staff of all the consortium members, who will gain the increased mobility and exchange the fluxes of culturally and institutionally diversified lecturers and qualified specialists

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert Finley

The Midwest Geological Sequestration Consortium (MGSC) has investigated the options for geological carbon dioxide (CO{sub 2}) sequestration in the 155,400-km{sup 2} (60,000-mi{sup 2}) Illinois Basin. Within the Basin, underlying most of Illinois, western Indiana, and western Kentucky, are relatively deeper and/or thinner coal resources, numerous mature oil fields, and deep salt-water-bearing reservoirs that are potentially capable of storing CO{sub 2}. The objective of this Assessment was to determine the technical and economic feasibility of using these geological sinks for long-term storage to avoid atmospheric release of CO{sub 2} from fossil fuel combustion and thereby avoid the potential for adverse climatemore » change. The MGSC is a consortium of the geological surveys of Illinois, Indiana, and Kentucky joined by six private corporations, five professional business associations, one interstate compact, two university researchers, two Illinois state agencies, and two consultants. The purpose of the Consortium is to assess carbon capture, transportation, and storage processes and their costs and viability in the three-state Illinois Basin region. The Illinois State Geological Survey serves as Lead Technical Contractor for the Consortium. The Illinois Basin region has annual emissions from stationary anthropogenic sources exceeding 276 million metric tonnes (304 million tons) of CO{sub 2} (>70 million tonnes (77 million tons) carbon equivalent), primarily from coal-fired electric generation facilities, some of which burn almost 4.5 million tonnes (5 million tons) of coal per year. Assessing the options for capture, transportation, and storage of the CO{sub 2} emissions within the region has been a 12-task, 2-year process that has assessed 3,600 million tonnes (3,968 million tons) of storage capacity in coal seams, 140 to 440 million tonnes (154 to 485 million tons) of capacity in mature oil reservoirs, 7,800 million tonnes (8,598 million tons) of capacity in saline reservoirs deep beneath geological structures, and 30,000 to 35,000 million tonnes (33,069 to 38,580 million tons) of capacity in saline reservoirs on a regional dip >1,219 m (4,000 ft) deep. The major part of this effort assessed each of the three geological sinks: coals, oil reservoirs, and saline reservoirs. We linked and integrated options for capture, transportation, and geological storage with the environmental and regulatory framework to define sequestration scenarios and potential outcomes for the region. Extensive use of Geographic Information Systems (GIS) and visualization technology was made to convey results to project sponsors, other researchers, the business community, and the general public. An action plan for possible technology validation field tests involving CO{sub 2} injection was included in a Phase II proposal (successfully funded) to the U.S. Department of Energy with cost sharing from Illinois Clean Coal Institute.« less

Department of Clinical Investigation Annual Research Progress Report, Fiscal Year 1984. Volume 1,

DTIC Science & Technology

1984-10-01

on a low dosage of medication . Technical Approach: None. Progress: The placebo has not been received from the company. Since the drug company...determine the effect of high dose Ar-C intensification therapy on the -. incidence of CNS relapse. - Technical Approach: All patients with a new...Enrolled to Date: 7 Date of Periodic Review Results Objective(s): To determine the incidence of

Total Factor Productivity Growth, Technical Progress & Efficiency Change in Vietnam Coal Industry - Nonparametric Approach

NASA Astrophysics Data System (ADS)

Phuong, Vu Hung

2018-03-01

This research applies Data Envelopment Analysis (DEA) approach to analyze Total Factor Productivity (TFP) and efficiency changes in Vietnam coal mining industry from 2007 to 2013. The TFP of Vietnam coal mining companies decreased due to slow technological progress and unimproved efficiency. The decadence of technical efficiency in many enterprises proved that the coal mining industry has a large potential to increase productivity through technical efficiency improvement. Enhancing human resource training, technology and research & development investment could help the industry to improve efficiency and productivity in Vietnam coal mining industry.

Development of Smart Precision Forest in Conifer Plantation in Japan Using Laser Scanning Data

NASA Astrophysics Data System (ADS)

Katoh, M.; Deng, S.; Takenaka, Y.; Cheung, K.; Oono, K.; Horisawa, M.; Hyyppä, J.; Yu, X.; Liang, X.; Wang, Y.

2017-10-01

Currently, the authors are planning to launch a consortium effort toward Japan's first smart precision forestry project using laser data and to develop this technology throughout the country. Smart precision forestry information gathered using the Nagano model (laser scanning from aircraft, drone, and backpack) is being developed to improve the sophistication of forest information, reduce labor-intensive work, maintain sustainable timber productivity, and facilitate supply chain management by laser sensing information in collaboration with industry, academia, and government. In this paper, we outline the research project and the technical development situation of unmanned aerial vehicle laser scanning.

Final Technical Report Overcoming Critical Barriers to U.S. Wind Power: A University-Industry Consortium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Acker, Tom; Kipple, Allison

The objective of this project was to develop a curriculum module involving the design and simulation of a wind turbine generator. Dr. Allison Kipple, Assistant Professor of Electrical Engineering, led development of the module, employing graduate and undergraduate students, and Dr. Tom Acker served as project manager and principal investigator. This objective was achieved resulting in development of curricular materials, implementation and revision of the materials in EE 364, a Northern Arizona University electrical engineering course in “Fundamentals of Electromagnetics,” and via dissemination of the curricular materials to a broad community including other universities.

A randomized, phase II study of pazopanib in castrate-sensitive prostate cancer: a University of Chicago Phase II Consortium/Department of Defense Prostate Cancer Clinical Trials Consortium study.

PubMed

Ward, J E; Karrison, T; Chatta, G; Hussain, M; Shevrin, D; Szmulewitz, R Z; O'Donnell, P H; Stadler, W M; Posadas, E M

2012-03-01

Intermittent androgen suppression (IAS) is an increasingly popular treatment option for castrate-sensitive prostate cancer. On the basis of previous data with anti-angiogenic strategies, we hypothesized that pan-inhibition of the vascular endothelial growth factor receptor using pazopanib during the IAS off period would result in prolonged time to PSA failure. Men with biochemically recurrent prostate cancer, whose PSA was <0.5 ng ml(-1) after 6 months of androgen deprivation therapy were randomized to pazopanib 800 mg daily or observation. The planned primary outcome was time to PSA progression >4.0 ng ml(-1). Thirty-seven patients were randomized. Of 18 patients randomized to pazopanib, at the time of study closure, 4 had progressive disease, 1 remained on treatment and 13 (72%) electively disenrolled, the most common reason being patient request due to grade 1/2 toxicity (8 patients). Two additional patients were removed from treatment due to adverse events. Of 19 patients randomized to observation, at the time of study closure, 4 had progressive disease, 7 remained under protocol-defined observation and 8 (42%) had disenrolled, most commonly due to non-compliance with protocol visits (3 patients). Because of high dropout rates in both arms, the study was halted. IAS is a treatment approach that may facilitate investigation of novel agents in the hormone-sensitive state. This trial attempted to investigate the role of antiangiogenic therapy in this setting, but encountered several barriers, including toxicities and patient non-compliance, which can make implementation of such a study difficult. Future investigative efforts in this arena should carefully consider drug toxicity and employ a design that maximizes patient convenience to reduce the dropout rate.

Photovoltaic Manufacturing Consortium (PVMC) – Enabling America’s Solar Revolution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Metacarpa, David

The U.S. Photovoltaic Manufacturing Consortium (US-PVMC) is an industry-led consortium which was created with the mission to accelerate the research, development, manufacturing, field testing, commercialization, and deployment of next-generation solar photovoltaic technologies. Formed as part of the U.S. Department of Energy's (DOE) SunShot initiative, and headquartered in New York State, PVMC is managed by the State University of New York Polytechnic Institute (SUNY Poly) at the Colleges of Nanoscale Science and Engineering. PVMC is a hybrid of industry-led consortium and manufacturing development facility, with capabilities for collaborative and proprietary industry engagement. Through its technology development programs, advanced manufacturing development facilities,more » system demonstrations, and reliability and testing capabilities, PVMC has demonstrated itself to be a recognized proving ground for innovative solar technologies and system designs. PVMC comprises multiple locations, with the core manufacturing and deployment support activities conducted at the Solar Energy Development Center (SEDC), and the core Si wafering and metrology technologies being headed out of the University of Central Florida. The SEDC provides a pilot line for proof-of-concept prototyping, offering critical opportunities to demonstrate emerging concepts in PV manufacturing, such as evaluations of innovative materials, system components, and PV system designs. The facility, located in Halfmoon NY, encompasses 40,000 square feet of dedicated PV development space. The infrastructure and capabilities housed at PVMC includes PV system level testing at the Prototype Demonstration Facility (PDF), manufacturing scale cell & module fabrication at the Manufacturing Development Facility (MDF), cell and module testing, reliability equipment on its PV pilot line, all integrated with a PV performance database and analytical characterizations for PVMC and its partners test and commercial arrays. Additional development and deployment support are also housed at the SEDC, such as cost modeling and cost model based development activities for PV and thin film modules, components, and system level designs for reduced LCOE through lower installation hardware costs, labor reductions, soft costs and reduced operations and maintenance costs. The progression of the consortium activities started with infrastructure and capabilities build out focused on CIGS thin film photovoltaics, with a particular focus on flexible cell and module production. As marketplace changes and partners objectives shifted, the consortium shifted heavily towards deployment and market pull activities including Balance of System, cost modeling, and installation cost reduction efforts along with impacts to performance and DER operational costs. The consortium consisted of a wide array of PV supply chain companies from equipment and component suppliers through national developers and installers with a particular focus on commercial scale deployments (typically 25 to 2MW installations). With DOE funding ending after the fifth budget period, the advantages and disadvantages of such a consortium is detailed along with potential avenues for self-sustainability is reviewed.« less

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 2 2014-07-01 2014-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 2 2013-07-01 2013-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 2 2011-07-01 2011-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

32 CFR 203.17 - Technical assistance provider reporting requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Technical assistance provider reporting requirements. 203.17 Section 203.17 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... technical assistance provider shall submit progress reports, financial status reports, materials prepared...

ISABELLE: a progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hahn, H

This paper discusses the ISABELLE project, which has the objective of constructing a high-energy proton colliding beam facility at Brookhaven National Laboratory. The major technical features of the intersecting storage accelerators with their projected performance are described. Application of over 1000 superconducting magnets in the two rings represents the salient characteristic of the machine. The status of the entire project, the technical progress made so far, and difficulties encountered are reviewed.

Final Technical Progress Report: Development of Low-Cost Suspension Heliostat; December 7, 2011 - December 6, 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bender, W.

2013-01-01

Final technical progress report of SunShot Incubator Solaflect Energy. The project succeeded in demonstrating that the Solaflect Suspension Heliostat design is viable for large-scale CSP installations. Canting accuracy is acceptable and is continually improving as Solaflect improves its understanding of this design. Cost reduction initiatives were successful, and there are still many opportunities for further development and further cost reduction.

NIEHS/FDA CLARITY-BPA research program update.

PubMed

Heindel, Jerrold J; Newbold, Retha R; Bucher, John R; Camacho, Luísa; Delclos, K Barry; Lewis, Sherry M; Vanlandingham, Michelle; Churchwell, Mona I; Twaddle, Nathan C; McLellen, Michelle; Chidambaram, Mani; Bryant, Matthew; Woodling, Kellie; Gamboa da Costa, Gonçalo; Ferguson, Sherry A; Flaws, Jodi; Howard, Paul C; Walker, Nigel J; Zoeller, R Thomas; Fostel, Jennifer; Favaro, Carolyn; Schug, Thaddeus T

2015-12-01

Bisphenol A (BPA) is a chemical used in the production of numerous consumer products resulting in potential daily human exposure to this chemical. The FDA previously evaluated the body of BPA toxicology data and determined that BPA is safe at current exposure levels. Although consistent with the assessment of some other regulatory agencies around the world, this determination of BPA safety continues to be debated in scientific and popular publications, resulting in conflicting messages to the public. Thus, the National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), and U.S. Food and Drug Administration (FDA) developed a consortium-based research program to link more effectively a variety of hypothesis-based research investigations and guideline-compliant safety testing with BPA. This collaboration is known as the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA). This paper provides a detailed description of the conduct of the study and a midterm update on progress of the CLARITY-BPA research program. Published by Elsevier Inc.

NIEHS/FDA CLARITY-BPA research program update

PubMed Central

Heindel, Jerrold J.; Newbold, Retha R.; Bucher, John R.; Camacho, Luísa; Delclos, K. Barry; Lewis, Sherry M.; Vanlandingham, Michelle; Churchwell, Mona I.; Twaddle, Nathan C.; McLellen, Michelle; Chidambaram, Mani; Bryant, Matthew; Woodling, Kellie; Gamboa da Costa, Gonçalo; Ferguson, Sherry A.; Flaws, Jodi; Howard, Paul C.; Walker, Nigel J.; Zoeller, R. Thomas; Fostel, Jennifer; Favaro, Carolyn; Schug, Thaddeus T.

2016-01-01

Bisphenol A (BPA) is a chemical used in the production of numerous consumer products resulting in potential daily human exposure to this chemical. The FDA previously evaluated the body of BPA toxicology data and determined that BPA is safe at current exposure levels. Although consistent with the assessment of some other regulatory agencies around the world, this determination of BPA safety continues to be debated in scientific and popular publications, resulting in conflicting messages to the public. Thus, the National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), and U.S Food and Drug Administration (FDA) developed a consortium-based research program to link more effectively a variety of hypothesis-based research investigations and guideline-compliant safety testing with BPA. This collaboration is known as the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA). This paper provides a detailed description of the conduct of the study and a midterm update on progress of the CLARITY-BPA research program. PMID:26232693

Progress in the capture, manipulation, and delivery of medical media and its impact on education, clinical care, and research.

PubMed

Bernardo, Theresa M; Malinowski, Robert P

2005-01-01

In this article, advances in the application of medical media to education, clinical care, and research are explored and illustrated with examples, and their future potential is discussed. Impact is framed in terms of the Sloan Consortium's five pillars of quality education: access; student and faculty satisfaction; learning effectiveness; and cost effectiveness. (Hiltz SR, Zhang Y, Turoff M. Studies of effectiveness of learning networks. In Bourne J, Moore J, ed. Elements of Quality Online Education. Needham, MA: Sloan-Consortium, 2002:15-45). The alternatives for converting analog media (text, photos, graphics, sound, video, animations, radiographs) to digital media and direct digital capture are covered, as are options for storing, manipulating, retrieving, and sharing digital collections. Diagnostic imaging is given particular attention, clarifying the difference between computerized radiography and digital radiography and explaining the accepted standard (DICOM) and the advantages of Web PACS. Some novel research applications of medical media are presented.

Coordinating Centers in Cancer-Epidemiology Research: The Asia Cohort Consortium Coordinating Center

PubMed Central

Rolland, Betsy; Smith, Briana R; Potter, John D

2011-01-01

Although it is tacitly recognized that a good Coordinating Center (CC) is essential to the success of any multi-site collaborative project, very little study has been done on what makes a CC successful, why some CCs fail, or how to build a CC that meets the needs of a given project. Moreover, very little published guidance is available, as few CCs outside the clinical-trial realm write about their work. The Asia Cohort Consortium (ACC) is a collaborative cancer-epidemiology research project that has made strong scientific and organizational progress over the past three years by focusing its CC on the following activities: collaboration development; operations management; statistical and data management; and communications infrastructure and tool development. Our hope is that, by sharing our experience building the ACC CC, we can begin a conversation about what it means to run a coordinating center for multi-institutional collaboration in cancer epidemiology, help other collaborative projects solve some of the issues associated with collaborative research, and learn from others. PMID:21803842

The Premenopausal Breast Cancer Collaboration: A pooling project of studies participating in the National Cancer Institute Cohort Consortium

PubMed Central

Nichols, Hazel B.; Schoemaker, Minouk J.; Wright, Lauren B.; McGowan, Craig; Brook, Mark N.; McClain, Kathleen M.; Jones, Michael E.; Adami, Hans-Olov; Agnoli, Claudia; Baglietto, Laura; Bernstein, Leslie; Bertrand, Kimberly A.; Blot, William J.; Boutron-Ruault, Marie-Christine; Butler, Lesley; Chen, Yu; Doody, Michele M.; Dossus, Laure; Eliassen, A. Heather; Giles, Graham G.; Gram, Inger T.; Hankinson, Susan E.; Hoffman-Bolton, Judy; Kaaks, Rudolf; Key, Timothy J.; Kirsh, Victoria A.; Kitahara, Cari M.; Koh, Woon-Puay; Larsson, Susanna C.; Lund, Eiliv; Ma, Huiyan; Merritt, Melissa A.; Milne, Roger L.; Navarro, Carmen; Overvad, Kim; Ozasa, Kotaro; Palmer, Julie R.; Peeters, Petra H.; Riboli, Elio; Rohan, Thomas E.; Sadakane, Atsuko; Sund, Malin; Tamimi, Rulla M.; Trichopoulou, Antonia; Vatten, Lars; Visvanathan, Kala; Weiderpass, Elisabete; Willett, Walter C.; Wolk, Alicja; Zeleniuch-Jacquotte, Anne; Zheng, Wei; Sandler, Dale P.; Swerdlow, Anthony J.

2017-01-01

Breast cancer is a leading cancer diagnosis among premenopausal women around the world. Unlike rates in postmenopausal women, incidence rates of advanced breast cancer have increased in recent decades for premenopausal women. Progress in identifying contributors to breast cancer risk among premenopausal women has been constrained by the limited numbers of premenopausal breast cancer cases in individual studies and resulting low statistical power to subcategorize exposures or to study specific subtypes. The Premenopausal Breast Cancer Collaborative Group was established to facilitate cohort-based analyses of risk factors for premenopausal breast cancer by pooling individual-level data from studies participating in the United States National Cancer Institute Cohort Consortium. This paper describes the Group, including the rationale for its initial aims related to pregnancy, obesity, and physical activity. We also describe the 20 cohort studies with data submitted to the Group by June 2016. The infrastructure developed for this work can be leveraged to support additional investigations. PMID:28600297

States and challenges for high-value biohythane production from waste biomass by dark fermentation technology.

PubMed

Liu, Zhidan; Zhang, Chong; Lu, Yuan; Wu, Xiao; Wang, Lang; Wang, Linjun; Han, Bing; Xing, Xin-Hui

2013-05-01

Hythane (H2+CH4) has attracted growing attention due to its versatile advantages as, for instance vehicle fuel. Biohythane consisting of biohydrogen and biomethane via two-stage fermentation is a potential high-value solution for the valorization of waste biomass resources and probably an alternative to the fossil based hythane. However, the significance and application potential of biohythane have not yet been fully recognized. This review focuses on the progress of biohydrogen and subsequent biomethane fermentation in terms of substrate, microbial consortium, reactor configuration, as well as the H2/CH4 ratio from the perspective of the feasibility of biohythane production in the past ten years. The current paper also covers how controls of the microbial consortium and bioprocess, system integration influence the biohythane productivity. Challenges and perspectives on biohythane technology will finally be addressed. This review provides a state-of-the-art technological insight into biohythane production by two-stage dark fermentation from biomass. Copyright © 2012 Elsevier Ltd. All rights reserved.

Consortium for Materials Development in Space

NASA Technical Reports Server (NTRS)

1999-01-01

During FY99 the Consortium for Materials Development in Space (CMDS) was reorganized around the following guidelines: industry driven, product focus, an industry led advisory council, focus on University of Alabama in Huntsville (UAH) core competencies, linkage to regional investment firms to assist commercialization and to take advantage of space flights. The organizational structure of the CMDS changed considerably during the year. The decision was made to reduce the organization to a Director and an Administrative Assistant. The various research projects, including the employees, were transferred to the appropriate UAH research center or college. In addition, an advisory council was established to provide direction and guidance to the CMDS to ensure a strong commercial focus. The council will (i) review CMDS commercial development plans and provide feedback, (ii) perform an annual evaluation of the Center's progress and present the results of this review to the UAH Vice President for Research, (iii) serve as an avenue of communication between the CMDS and its commercial partners, and (iv) serve as an ambassador and advocate for the CMDS.

Measurement of solids motion in gas-fluidized beds. Technical progress report, 1 October 1982-31 December 1982

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, M.M.; Chao, B.T.

This technical progress report covers the progress made during the fifth quarter of the project entitled Measurements of Solids Motion in Gas Fluidized Beds under Grant No. DOE-F22-81PC40804 during the period 1 October through 31 December 1982. The research concerns the measurement of solids particle velocity distribution and residence time distribution using the Computer-Aided Particle Tracking Facility (CAPTF) at the University of Illinois at Urbana-Champaign. The experimental equipment and measuring methods used to determine particle size distribution and particle motion and the results obtained are presented.

The 1996 NAEP Technical Report.

ERIC Educational Resources Information Center

Allen, Nancy L.; Carlson, James E.; Zelenak, Christine A.

This report documents the design, administration, and data analysis procedure of the National Assessment of Education Progress (NAEP) for 1996. It indicates the technical decisions that were made and the rationale behind them. Detailed substantive findings are not presented in this report. These chapters provide technical information about the…

Lincoln County nuclear waste project. Quarterly progress report, October 1, 1991--December 31, 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This document included the following three progress reports to the Yucca Mountain Project Office on radioactive waste storage in Lincoln County, Nevada: financial status report; federal cash transactions report; and technical progress report.

Lincoln County nuclear waste project. Quarterly progress report, January 1, 1992--March 31, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This document included the following three progress reports to the Yucca Mountain Project Office on radioactive waste storage in Lincoln County, Nevada: financial status report; federal cash transactions report; and technical progress report.

Lincoln County nuclear waste project quarterly progress report, April 1, 1992--June 30, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This document included the following three progress reports to the Yucca Mountain Project Office on radioactive waste storage in Lincoln County, Nevada: financial status report; federal cash transactions report; and technical progress report.

Final Technical Report. DeepCwind Consortium Research Program. January 15, 2010 - March 31, 2013

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dagher, Habib; Viselli, Anthony; Goupee, Andrew

This is the final technical report for the U.S. Department of Energy-funded program, DE-0002981: DeepCwind Consortium Research Program. The project objective was the partial validation of coupled models and optimization of materials for offshore wind structures. The United States has a great opportunity to harness an indigenous abundant renewable energy resource: offshore wind. In 2010, the National Renewable Energy Laboratory (NREL) estimated there to be over 4,000 GW of potential offshore wind energy found within 50 nautical miles of the US coastlines (Musial and Ram, 2010). The US Energy Information Administration reported the total annual US electric energy generation inmore » 2010 was 4,120 billion kilowatt-hours (equivalent to 470 GW) (US EIA, 2011), slightly more than 10% of the potential offshore wind resource. In addition, deep water offshore wind is the dominant US ocean energy resource available comprising 75% of the total assessed ocean energy resource as compared to wave and tidal resources (Musial, 2008). Through these assessments it is clear offshore wind can be a major contributor to US energy supplies. The caveat to capturing offshore wind along many parts of the US coast is deep water. Nearly 60%, or 2,450 GW, of the estimated US offshore wind resource is located in water depths of 60 m or more (Musial and Ram, 2010). At water depths over 60 m building fixed offshore wind turbine foundations, such as those found in Europe, is likely economically infeasible (Musial et al., 2006). Therefore floating wind turbine technology is seen as the best option for extracting a majority of the US offshore wind energy resource. Volume 1 - Test Site; Volume 2 - Coupled Models; and Volume 3 - Composite Materials« less

Undergraduate research studies program at participating institutions of the HBCU Fossil Energy Consortium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhatia, S.C.; Cardelino, B.H.; Hall, J.H. Jr.

1990-01-31

This report consists of five quarterly progress reports from four participating universities. The titles of the projects are: Competition of NO and SO{sub 2} for OH generated within electrical aerosol analyzers; Dispersed iron catalysts for coal gasification; Catalytic gasification of coal chars by potassium sulfate and ferrous sulfate mixtures; Removal of certain toxic heavy metal ions in coal conversion process wastewaters; and Study of coal liquefaction catalysts. All reports have been indexed separately for inclusion on the data base. (CK)

Computational approaches to identify functional genetic variants in cancer genomes

PubMed Central

Gonzalez-Perez, Abel; Mustonen, Ville; Reva, Boris; Ritchie, Graham R.S.; Creixell, Pau; Karchin, Rachel; Vazquez, Miguel; Fink, J. Lynn; Kassahn, Karin S.; Pearson, John V.; Bader, Gary; Boutros, Paul C.; Muthuswamy, Lakshmi; Ouellette, B.F. Francis; Reimand, Jüri; Linding, Rune; Shibata, Tatsuhiro; Valencia, Alfonso; Butler, Adam; Dronov, Serge; Flicek, Paul; Shannon, Nick B.; Carter, Hannah; Ding, Li; Sander, Chris; Stuart, Josh M.; Stein, Lincoln D.; Lopez-Bigas, Nuria

2014-01-01

The International Cancer Genome Consortium (ICGC) aims to catalog genomic abnormalities in tumors from 50 different cancer types. Genome sequencing reveals hundreds to thousands of somatic mutations in each tumor, but only a minority drive tumor progression. We present the result of discussions within the ICGC on how to address the challenge of identifying mutations that contribute to oncogenesis, tumor maintenance or response to therapy, and recommend computational techniques to annotate somatic variants and predict their impact on cancer phenotype. PMID:23900255

Index to Nuclear Safety: a technical progress review by chronology, permuted title, and author, Volume 18 (1) through Volume 22 (6)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cottrell, W.B.; Passiakos, M.

This index to Nuclear Safety covers articles published in Nuclear Safety, Volume 18, Number 1 (January-February 1977) through Volume 22, Number 6 (November-December 1981). The index is divided into three section: a chronological list of articles (including abstracts), a permuted-title (KWIC) index, and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. Over 300 technical articles published in Nuclear Safety in the last 5 years are listed in this index.

Human System Simulation in Support of Human Performance Technical Basis at NPPs

DOE Office of Scientific and Technical Information (OSTI.GOV)

David Gertman; Katya Le Blanc; alan mecham

2010-06-01

This paper focuses on strategies and progress toward establishing the Idaho National Laboratory’s (INL’s) Human Systems Simulator Laboratory at the Center for Advanced Energy Studies (CAES), a consortium of Idaho State Universities. The INL is one of the National Laboratories of the US Department of Energy. One of the first planned applications for the Human Systems Simulator Laboratory is implementation of a dynamic nuclear power plant simulation (NPP) where studies of operator workload, situation awareness, performance and preference will be carried out in simulated control rooms including nuclear power plant control rooms. Simulation offers a means by which to reviewmore » operational concepts, improve design practices and provide a technical basis for licensing decisions. In preparation for the next generation power plant and current government and industry efforts in support of light water reactor sustainability, human operators will be attached to a suite of physiological measurement instruments and, in combination with traditional Human Factors Measurement techniques, carry out control room tasks in simulated advanced digital and hybrid analog/digital control rooms. The current focus of the Human Systems Simulator Laboratory is building core competence in quantitative and qualitative measurements of situation awareness and workload. Of particular interest is whether introduction of digital systems including automated procedures has the potential to reduce workload and enhance safety while improving situation awareness or whether workload is merely shifted and situation awareness is modified in yet to be determined ways. Data analysis is carried out by engineers and scientists and includes measures of the physical and neurological correlates of human performance. The current approach supports a user-centered design philosophy (see ISO 13407 “Human Centered Design Process for Interactive Systems, 1999) wherein the context for task performance along with the requirements of the end-user are taken into account during the design process and the validity of design is determined through testing of real end users« less

77 FR 16250 - Notice of Proposed Information Collection for Public Comment; Office of Native American Programs...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... Information Collection for Public Comment; Office of Native American Programs (ONAP) Training and Technical... subject proposal. The data required by Office of Native American Programs Training and Technical... progress. The data identifies needs, outputs and outcomes of the training and technical assistance. DATES...

Isprs Student Consortium: the Network of Youth in Geoinformation Society

NASA Astrophysics Data System (ADS)

Kivilcim, C. O.; Sterenczak, K.; Kanjir, U.; Sengul, A.; Stavbar, G.; Pakdil, M. E.; Lobo, E.; Oo, K. S.

2012-07-01

The ISPRS Student Consortium (SC) initiative started at the 20th ISPRS Congress in Istanbul, 2004.After four years of volunteer activity, an official structure for volunteers was needed. With the implementation of the SC Statutes in the ISPRS Beijing Congress in 2008, the first ISPRS Student Consortium Board Members were elected. Since this day, SC volunteers and supporters have continued to contribute through numerous activities in order to promote the Society and connect young people with a similar interest in the profession. So far, promotional activities have taken place in various places in Europe, North and Central America, Asia and Australia. SC members have not only participated in the events, but also organized activities, taken responsibilities and represented youth in ISPRS midterm symposiums and ISPRS Centenary Celebrations as well as other related events. Summer schools, as the main SC event, are organized with the help of ISPRS TC VI/5 and are focused on the needs and interests of scientific communities around the world. The SC community has been constantly growing with almost 750 members over 85 countries at present, registered through our self-developed website. The organization also publishes its own Newsletter four times per year, with the intention to transmit the messages and news from ISPRS and the SC. The Newsletter is a perfect platform for presenting useful technical, educational and informational material prepared by members and distributed freely among the supporters. Throughout time, the SC has received guiding, motivational and administrative support from WG VI/5 as well as TC VI and the ISPRS Council. Activities have been financially supported by foundations, commercial enterprises and academic organizations and many SC members have received grants to present their work in different scientific events. In addition, the SC has started and established permanent connections and signed agreements for better networking with the youth organizations of the sister Societies of ISPRS. This paper presents the achievements reached over the last four years, the experiences of the SC Board and Regional Representatives and the feedback from our members. It provides an insight for the youth organizations run under other scientific and technical societies. A vision for the continuum of the activities and establishing regional and national developments are suggested. A revised road-map for the future is outlined in the conclusion.

Social inequalities in the face of scientific and technological development: an antinomy or an historic problem?

PubMed

Delgado, Guilherme Costa

2017-07-01

This paper aims to conduct a conceptual analysis of the relationship between scientific and technical progress and social equality, or the reduction of inequalities. We examine this relationship by drawing on three theoretical perspectives: 1) ethical economics, championed by classical economic thinkers and centered on utilitarian self-interest, 2) Mainstream theories of economic development espousing the endogenous link between labor productivity growth and technical progress, 3) the critique of theories of economic development that emerged in the second half of the twentieth century, including Celso Furtado's critique of the theory of underdevelopment, emphasizing the prevalence of egalitarian tendencies, and ecological economics, which suggest alternative paths to those set by "classical" theories of development. The fundamental antinomy posed by the title of this article, characterized by an intrinsic contradiction between technical progress and social equality, strictly presupposes the ethical economics perspective, dominated by the social relations that constitute the "social order".

Support of Gulf of Mexico Hydrate Research Consortium: Activities to Support Establishment of a Sea Floor Monitoring Station Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carol Lutken

The Gulf of Mexico Hydrates Research Consortium (GOM-HRC) was established in 1999 to assemble leaders in gas hydrates research. The Consortium is administered by the Center for Marine Resources and Environmental Technology, CMRET, at the University of Mississippi. The primary objective of the group is to design and emplace a remote monitoring station or sea floor observatory (MS/SFO) on the sea floor in the northern Gulf of Mexico by the year 2007, in an area where gas hydrates are known to be present at, or just below, the sea floor. This mission, although unavoidably delayed by hurricanes and other disturbances,more » necessitates assembling a station that will monitor physical and chemical parameters of the marine environment, including sea water and sea-floor sediments, on a more-or-less continuous basis over an extended period of time. In 2005, biological monitoring, as a means of assessing environmental health, was added to the mission of the MS/SFO. Establishment of the Consortium has succeeded in fulfilling the critical need to coordinate activities, avoid redundancies and communicate effectively among researchers in the arena of gas hydrates research. Complementary expertise, both scientific and technical, has been assembled to promote innovative research methods and construct necessary instrumentation. The observatory has now achieved a microbial dimension in addition to the geophysical, geological, and geochemical components it had already included. Initial components of the observatory, a probe that collects pore-fluid samples and another that records sea floor temperatures, were deployed in Mississippi Canyon 118 in May of 2005. Follow-up deployments, planned for fall 2005, had to be postponed due to the catastrophic effects of Hurricane Katrina (and later, Rita) on the Gulf Coast. Station/observatory completion, anticipated for 2007, will likely be delayed by at least one year. The CMRET has conducted several research cruises during this reporting period: one in April, one in June, one in September. April's effort was dedicated to surveying the mound at MC118 with the Surface-Source-Deep-Receiver (SSDR) seismic surveying system. This survey was completed in June and water column and bottom samples were collected via box coring. A microbial filtering system developed by Consortium participants at the University of Georgia was also deployed, run for {approx}12 hours and retrieved. The September cruise, designed to deploy, test, and in some cases recover, geochemical and microbial instruments and experiments took place aboard Harbor Branch's Seward Johnson and employed the Johnson SeaLink manned submersible. The seafloor monitoring station/observatory is funded approximately equally by three federal Agencies: Minerals Management Services (MMS) of the Department of the Interior (DOI), National Energy Technology Laboratory (NETL) of the Department of Energy (DOE), and the National Institute for Undersea Science and Technology (NIUST), an agency of the National Oceanographic and Atmospheric Administration (NOAA). Subcontractors with FY03 funding fulfilled their technical reporting requirements in a previously submitted report (41628R10). Only unresolved matching funds issues remain and will be addressed in the report of the University of Mississippi's Office of Research and Sponsored Programs. In addition, Barrodale Computing Services Ltd. (BCS) completed their work; their final report is the bulk of the semiannual report that precedes (abstract truncated)« less

Developments in Technical Education in the British Caribbean, 1940-60.

ERIC Educational Resources Information Center

Pemberton, S. Macpherson

The paper discusses developments in technical education in the British West Indies from 1940-1960 emphasizing the relation between education and economic development. The objective is to analyze the economic basis of progress in technical education. The document is presented in four chapters. Chapter I summarizes historical background prior to…

Programs of Study: Year 2 Joint Technical Report. Research Snapshot

ERIC Educational Resources Information Center

National Research Center for Career and Technical Education, 2010

2010-01-01

In January 2010, the National Research Center for Career and Technical Education (NRCCTE) issued a progress report on three studies being conducted by the Center that examine the implementation and outcomes of Programs of Study (POS), which were required in the 2006 reauthorization of the federal legislation for career and technical education…

Two-axis antenna positioning mechanism

NASA Technical Reports Server (NTRS)

Herald, Michelle; Wai, Leilani C.

1994-01-01

The two-axis antenna positioning mechanism (TAAPM) is used to position three Ku-band and one C-band spot antennas on the INTELSAT 7 (I-7) spacecraft, which is a commercial telecommunications satellite purchased and operated by INTELSAT, an international consortium. The first I-7 was successfully launched on 22 Oct. 1993 from French Guiana on an Ariane launch vehicle. The TAAPM's on the first I-7 satellite successfully completed their in-orbit functional testing. The TAAPM was an entirely new design for Space Systems/Loral. This paper will describe the spacecraft/system requirements and application of the TAAPM and present the technical findings of TAAPM qualification and protoflight testing.

Newborn Sequencing in Genomic Medicine and Public Health

PubMed Central

Agrawal, Pankaj B.; Bailey, Donald B.; Beggs, Alan H.; Brenner, Steven E.; Brower, Amy M.; Cakici, Julie A.; Ceyhan-Birsoy, Ozge; Chan, Kee; Chen, Flavia; Currier, Robert J.; Dukhovny, Dmitry; Green, Robert C.; Harris-Wai, Julie; Holm, Ingrid A.; Iglesias, Brenda; Joseph, Galen; Kingsmore, Stephen F.; Koenig, Barbara A.; Kwok, Pui-Yan; Lantos, John; Leeder, Steven J.; Lewis, Megan A.; McGuire, Amy L.; Milko, Laura V.; Mooney, Sean D.; Parad, Richard B.; Pereira, Stacey; Petrikin, Joshua; Powell, Bradford C.; Powell, Cynthia M.; Puck, Jennifer M.; Rehm, Heidi L.; Risch, Neil; Roche, Myra; Shieh, Joseph T.; Veeraraghavan, Narayanan; Watson, Michael S.; Willig, Laurel; Yu, Timothy W.; Urv, Tiina; Wise, Anastasia L.

2017-01-01

The rapid development of genomic sequencing technologies has decreased the cost of genetic analysis to the extent that it seems plausible that genome-scale sequencing could have widespread availability in pediatric care. Genomic sequencing provides a powerful diagnostic modality for patients who manifest symptoms of monogenic disease and an opportunity to detect health conditions before their development. However, many technical, clinical, ethical, and societal challenges should be addressed before such technology is widely deployed in pediatric practice. This article provides an overview of the Newborn Sequencing in Genomic Medicine and Public Health Consortium, which is investigating the application of genome-scale sequencing in newborns for both diagnosis and screening. PMID:28096516

German national femtosecond technology project (FST)

NASA Astrophysics Data System (ADS)

Dausinger, Friedrich

2002-06-01

The German federal government started the funding of a national project intended to exploit the potential of femtosecond technology. In a forgoing competition five research consortia had been successful and have started now together with an adjoin research consortium their investigations in the following fields: (i) micro-machining of technical materials for microstructuring and drilling, (ii) medical therapy in: ophthalmology, dentistry, neurology and ear surgery, (iii) metrology, (iv) laser safety, (v) x- ray generation. Lasers, systems and technologies required in these potential fields of applications will be investigated. The program aims at industrial success and is dominated by industrial partners, therefore. The more fundamental research is done in university institutes and research centers.

End-to-end observatory software modeling using domain specific languages

NASA Astrophysics Data System (ADS)

Filgueira, José M.; Bec, Matthieu; Liu, Ning; Peng, Chien; Soto, José

2014-07-01

The Giant Magellan Telescope (GMT) is a 25-meter extremely large telescope that is being built by an international consortium of universities and research institutions. Its software and control system is being developed using a set of Domain Specific Languages (DSL) that supports a model driven development methodology integrated with an Agile management process. This approach promotes the use of standardized models that capture the component architecture of the system, that facilitate the construction of technical specifications in a uniform way, that facilitate communication between developers and domain experts and that provide a framework to ensure the successful integration of the software subsystems developed by the GMT partner institutions.

Interdisciplinary Collaboration amongst Colleagues and between Initiatives with the Magnetics Information Consortium (MagIC) Database

NASA Astrophysics Data System (ADS)

Minnett, R.; Koppers, A. A. P.; Jarboe, N.; Tauxe, L.; Constable, C.; Jonestrask, L.; Shaar, R.

2014-12-01

Earth science grand challenges often require interdisciplinary and geographically distributed scientific collaboration to make significant progress. However, this organic collaboration between researchers, educators, and students only flourishes with the reduction or elimination of technological barriers. The Magnetics Information Consortium (http://earthref.org/MagIC/) is a grass-roots cyberinfrastructure effort envisioned by the geo-, paleo-, and rock magnetic scientific community to archive their wealth of peer-reviewed raw data and interpretations from studies on natural and synthetic samples. MagIC is dedicated to facilitating scientific progress towards several highly multidisciplinary grand challenges and the MagIC Database team is currently beta testing a new MagIC Search Interface and API designed to be flexible enough for the incorporation of large heterogeneous datasets and for horizontal scalability to tens of millions of records and hundreds of requests per second. In an effort to reduce the barriers to effective collaboration, the search interface includes a simplified data model and upload procedure, support for online editing of datasets amongst team members, commenting by reviewers and colleagues, and automated contribution workflows and data retrieval through the API. This web application has been designed to generalize to other databases in MagIC's umbrella website (EarthRef.org) so the Geochemical Earth Reference Model (http://earthref.org/GERM/) portal, Seamount Biogeosciences Network (http://earthref.org/SBN/), EarthRef Digital Archive (http://earthref.org/ERDA/) and EarthRef Reference Database (http://earthref.org/ERR/) will benefit from its development.

Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02

PubMed Central

Lee, Eudocia Q.; Kuhn, John; Lamborn, Kathleen R.; Abrey, Lauren; DeAngelis, Lisa M.; Lieberman, Frank; Robins, H. Ian; Chang, Susan M.; Yung, W. K. Alfred; Drappatz, Jan; Mehta, Minesh P.; Levin, Victor A.; Aldape, Kenneth; Dancey, Janet E.; Wright, John J.; Prados, Michael D.; Cloughesy, Timothy F.; Gilbert, Mark R.; Wen, Patrick Y.

2012-01-01

The activity of single-agent targeted molecular therapies in glioblastoma has been limited to date. The North American Brain Tumor Consortium examined the safety, pharmacokinetics, and efficacy of combination therapy with sorafenib, a small molecule inhibitor of Raf, vascular endothelial growth factor receptor 2, and platelet-derived growth factor receptor–β, and temsirolimus (CCI-779), an inhibitor of mammalian target of rapamycin. This was a phase I/II study. The phase I component used a standard 3 × 3 dose escalation scheme to determine the safety and tolerability of this combination therapy. The phase II component used a 2-stage design; the primary endpoint was 6-month progression-free survival (PFS6) rate. Thirteen patients enrolled in the phase I component. The maximum tolerated dosage (MTD) for combination therapy was sorafenib 800 mg daily and temsirolimus 25 mg once weekly. At the MTD, grade 3 thrombocytopenia was the dose-limiting toxicity. Eighteen patients were treated in the phase II component. At interim analysis, the study was terminated and did not proceed to the second stage. No patients remained progression free at 6 months. Median PFS was 8 weeks. The toxicity of this combination therapy resulted in a maximum tolerated dose of temsirolimus that was only one-tenth of the single-agent dose. Minimal activity in recurrent glioblastoma multiforme was seen at the MTD of the 2 combined agents. PMID:23099651

Proceedings: Computer Science and Data Systems Technical Symposium, volume 1

NASA Technical Reports Server (NTRS)

Larsen, Ronald L.; Wallgren, Kenneth

1985-01-01

Progress reports and technical updates of programs being performed by NASA centers are covered. Presentations in viewgraph form are included for topics in three categories: computer science, data systems and space station applications.

Final Report for the Development of the NASA Technical Report Server (NTRS)

NASA Technical Reports Server (NTRS)

Nelson, Michael L.

2005-01-01

The author performed a variety of research, development and consulting tasks for NASA Langley Research Center in the area of digital libraries (DLs) and supporting technologies, such as the Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH). In particular, the development focused on the NASA Technical Report Server (NTRS) and its transition from a distributed searching model to one that uses the OAI-PMH. The Open Archives Initiative (OAI) is an international consortium focused on furthering the interoperability of DLs through the use of "metadata harvesting". The OAI-PMH version of NTRS went into public production on April 28, 2003. Since that time, it has been extremely well received. In addition to providing the NTRS user community with a higher level of service than the previous, distributed searching version of NTRS, it has provided more insight into how the user community uses NTRS in a variety of deployment scenarios. This report details the design, implementation and maintenance of the NTRS. Source code is included in the appendices.

World Wide Web and Internet: applications for radiologists.

PubMed

Wunderbaldinger, P; Schima, W; Turetschek, K; Helbich, T H; Bankier, A A; Herold, C J

1999-01-01

Global exchange of information is one of the major sources of scientific progress in medicine. For management of the rapidly growing body of medical information, computers and their applications have become an indispensable scientific tool. Approximately 36 million computer users are part of a worldwide network called the Internet or "information highway" and have created a new infrastructure to promote rapid and efficient access to medical, and thus also to radiological, information. With the establishment of the World Wide Web (WWW) by a consortium of computer users who used a standardized, nonproprietary syntax termed HyperText Markup Language (HTML) for composing documents, it has become possible to provide interactive multimedia presentations to a wide audience. The extensive use of images in radiology makes education, worldwide consultation (review) and scientific presentation via the Internet a major beneficiary of this technical development. This is possible, since both information (text) as well as medical images can be transported via the Internet. Presently, the Internet offers an extensive database for radiologists. Since many radiologists and physicians have to be considered "Internet novices" and, hence, cannot yet avail themselves of the broad spectrum of the Internet, the aim of this article is to present a general introduction to the WWW/Internet and its applications for radiologists. All Internet sites mentioned in this article can be found at the following Internet address: http://www.univie.ac. at/radio/radio.html (Department of Radiology, University of Vienna)

Virtual Modeling for Cities of the Future. State-Of Art and Virtual Modeling for Cities of the Future. State-Of Art AN

NASA Astrophysics Data System (ADS)

Valencia, J.; Muñoz-Nieto, A.; Rodriguez-Gonzalvez, P.

2015-02-01

3D virtual modeling, visualization, dissemination and management of urban areas is one of the most exciting challenges that must face geomatics in the coming years. This paper aims to review, compare and analyze the new technologies, policies and software tools that are in progress to manage urban 3D information. It is assumed that the third dimension increases the quality of the model provided, allowing new approaches to urban planning, conservation and management of architectural and archaeological areas. Despite the fact that displaying 3D urban environments is an issue nowadays solved, there are some challenges to be faced by geomatics in the coming future. Displaying georeferenced linked information would be considered the first challenge. Another challenge to face is to improve the technical requirements if this georeferenced information must be shown in real time. Are there available software tools ready for this challenge? Are they useful to provide services required in smart cities? Throughout this paper, many practical examples that require 3D georeferenced information and linked data will be shown. Computer advances related to 3D spatial databases and software that are being developed to convert rendering virtual environment to a new enriched environment with linked information will be also analyzed. Finally, different standards that Open Geospatial Consortium has assumed and developed regarding the three-dimensional geographic information will be reviewed. Particular emphasis will be devoted on KML, LandXML, CityGML and the new IndoorGML.

25 CFR 1000.73 - Once a Tribe/Consortium has been awarded a grant, may the Tribe/Consortium obtain information...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Once a Tribe/Consortium has been awarded a grant, may the Tribe/Consortium obtain information from a non-BIA bureau? 1000.73 Section 1000.73 Indians OFFICE OF THE... § 1000.73 Once a Tribe/Consortium has been awarded a grant, may the Tribe/Consortium obtain information...

Technical progress in silicon sheet growth under DOE/JPL FSA program, 1975-1986

NASA Technical Reports Server (NTRS)

Kalejs, J. P.

1986-01-01

The technical progress made in the Silicon Sheet Growth Program during its 11 years was reviewed. At present, in 1986, only two of the original 9 techniques have survived to the start-up, pilot-plant stage in industry. These two techniques are the edge-defined, film-fed growth (EFG) technique that produces closed shape polygons, and the WEB dendritic technique that produces single ribbons. Both the status and future concerns of the EFG and WEB techniques were discussed.

Annual Progress Report (17th) and 1992-97 Renewal Proposal Interactive Graphics for Molecular Studies

DTIC Science & Technology

1991-01-24

Molecular Graphics, vol. 6, No. 4 (Dec. 1988), p. 223. Turk, Greg, "Interactive Collision Detection for Molecular Graphics," M.S. thesis , UNC-Chapel Hill...Problem," Master’s thesis , UNC Department of Computer Science Technical Report #TR87-013, May 1987. Pique, ME., "Technical Trends in Molecular Graphics...AD-A236 598 Seventeenth Annual Progress Report and 1992-97 Renewal Proposal Interactive Graphics for Molecular Studies TR91-020 January 24, 1991 red

Enhanced oil recovery utilizing high-angle wells in the Frontier Formation, Badger Basin Field, Park County, Wyoming. Quarterly technical progress report, 1 March 1993--30 June 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fortmann, R.G.; Walker, J.P.

1993-07-10

Sierra Energy Company`s targeted goals during the third quarter of this Cooperative Agreement included the following objectives from the Statement of Work: in Phase 2A, completion of subtask 2.1.2--acquire best possible field data in the 3-D seismic program; and initiation of Subtask 2.1.3--process acquired 3-D seismic data. Technical progress is described for these tasks.

10 CFR 603.1100 - Contracting officer's post-award responsibilities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... technical progress, financial status, and future program plans. (b) Tracking and processing of reports... progress reports, and patent reports. (c) Handling payment requests and related matters. For a TIA using advance payments, that includes reviews of progress to verify that there is continued justification for...

7 CFR 3402.23 - Documentation of progress on funded projects.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the academic program due to unsatisfactory academic progress; or voluntarily withdraws from the Fellowship or the academic program. If a Fellow has not completed all degree requirements at the end of the... database contains narrative project information, progress/impact statements, and final technical reports...

7 CFR 3402.23 - Documentation of progress on funded projects.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the academic program due to unsatisfactory academic progress; or voluntarily withdraws from the Fellowship or the academic program. If a Fellow has not completed all degree requirements at the end of the... database contains narrative project information, progress/impact statements, and final technical reports...

7 CFR 3402.23 - Documentation of progress on funded projects.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the academic program due to unsatisfactory academic progress; or voluntarily withdraws from the Fellowship or the academic program. If a Fellow has not completed all degree requirements at the end of the... database contains narrative project information, progress/impact statements, and final technical reports...

7 CFR 3402.23 - Documentation of progress on funded projects.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the academic program due to unsatisfactory academic progress; or voluntarily withdraws from the Fellowship or the academic program. If a Fellow has not completed all degree requirements at the end of the... database contains narrative project information, progress/impact statements, and final technical reports...

ESPRESSO: the ultimate rocky exoplanets hunter for the VLT

NASA Astrophysics Data System (ADS)

Mégevand, Denis; Zerbi, Filippo M.; Cabral, Alexandre; Di Marcantonio, Paolo; Amate, Manuel; Pepe, Francesco; Cristiani, Stefano; Rebolo, Rafael; Santos, Nuno C.; Dekker, Hans; Abreu, Manuel; Affolter, Michael; Avila, Gerardo; Baldini, Veronica; Bristow, Paul; Broeg, Christopher; Carvas, Pedro; Cirami, Roberto; Coelho, João.; Comari, Maurizio; Conconi, Paolo; Coretti, Igor; Cupani, Guido; D'Odorico, Valentina; De Caprio, Vincenzo; Delabre, Bernard; Figueira, Pedro; Fleury, Michel; Fragoso, Ana; Genolet, Ludovic; Gomes, Ricardo; Gonzalez Hernandez, Jonay; Hughes, Ian; Iwert, Olaf; Kerber, Florian; Landoni, Marco; Lima, Jorge; Lizon, Jean-Louis; Lovis, Christophe; Maire, Charles; Mannetta, Marco; Martins, Carlos; Moitinho, André; Molaro, Paolo; Monteiro, Manuel; Rasilla, José Luis; Riva, Marco; Santana Tschudi, Samuel; Santin, Paolo; Sosnowska, Danuta; Sousa, Sergio; Spanò, Paolo; Tenegi, Fabio; Toso, Giorgio; Vanzella, Eros; Viel, Matteo; Zapatero Osorio, Maria Rosa

2012-09-01

ESPRESSO, the VLT rocky exoplanets hunter, will combine the efficiency of modern echelle spectrograph with extreme radial-velocity precision. It will be installed at Paranal on ESO's VLT in order to achieve a gain of two magnitudes with respect to its predecessor HARPS, and the instrumental radial-velocity precision will be improved to reach 10 cm/s level. We have constituted a Consortium of astronomical research institutes to fund, design and build ESPRESSO on behalf of and in collaboration with ESO, the European Southern Observatory. The project has passed the preliminary design review in November 2011. The spectrograph will be installed at the so-called "Combined Coudé Laboratory" of the VLT, it will be linked to the four 8.2 meters Unit Telescopes (UT) through four optical "Coudé trains" and will be operated either with a single telescope or with up to four UTs. In exchange of the major financial and human effort the building Consortium will be awarded with guaranteed observing time (GTO), which will be invested in a common scientific program. Thanks to its characteristics and the ability of combining incoherently the light of 4 large telescopes, ESPRESSO will offer new possibilities in many fields of astronomy. Our main scientific objectives are, however, the search and characterization of rocky exoplanets in the habitable zone of quiet, near-by G to M-dwarfs, and the analysis of the variability of fundamental physical constants. In this paper, we present the ambitious scientific objectives, the capabilities of ESPRESSO, the technical solutions for the system and its subsystems, enlightening the main differences between ESPRESSO and its predecessors. The project aspects of this facility are also described, from the consortium and partnership structure to the planning phases and milestones.

OpenFIRE - A Web GIS Service for Distributing the Finnish Reflection Experiment Datasets

NASA Astrophysics Data System (ADS)

Väkevä, Sakari; Aalto, Aleksi; Heinonen, Aku; Heikkinen, Pekka; Korja, Annakaisa

2017-04-01

The Finnish Reflection Experiment (FIRE) is a land-based deep seismic reflection survey conducted between 2001 and 2003 by a research consortium of the Universities of Helsinki and Oulu, the Geological Survey of Finland, and a Russian state-owned enterprise SpetsGeofysika. The dataset consists of 2100 kilometers of high-resolution profiles across the Archaean and Proterozoic nuclei of the Fennoscandian Shield. Although FIRE data have been available on request since 2009, the data have remained underused outside the original research consortium. The original FIRE data have been quality-controlled. The shot gathers have been cross-checked and comprehensive errata has been created. The brute stacks provided by the Russian seismic contractor have been reprocessed into seismic sections and replotted. A complete documentation of the intermediate processing steps is provided together with guidelines for setting up a computing environment and plotting the data. An open access web service "OpenFIRE" for the visualization and the downloading of FIRE data has been created. The service includes a mobile-responsive map application capable of enriching seismic sections with data from other sources such as open data from the National Land Survey and the Geological Survey of Finland. The AVAA team of the Finnish Open Science and Research Initiative has provided a tailored Liferay portal with necessary web components such as an API (Application Programming Interface) for download requests. INSPIRE (Infrastructure for Spatial Information in Europe) -compliant discovery metadata have been produced and geospatial data will be exposed as Open Geospatial Consortium standard services. The technical guidelines of the European Plate Observing System have been followed and the service could be considered as a reference application for sharing reflection seismic data. The OpenFIRE web service is available at www.seismo.helsinki.fi/openfire

Nuclear Fabrication Consortium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levesque, Stephen

2013-04-05

This report summarizes the activities undertaken by EWI while under contract from the Department of Energy (DOE) Office of Nuclear Energy (NE) for the management and operation of the Nuclear Fabrication Consortium (NFC). The NFC was established by EWI to independently develop, evaluate, and deploy fabrication approaches and data that support the re-establishment of the U.S. nuclear industry: ensuring that the supply chain will be competitive on a global stage, enabling more cost-effective and reliable nuclear power in a carbon constrained environment. The NFC provided a forum for member original equipment manufactures (OEM), fabricators, manufacturers, and materials suppliers to effectivelymore » engage with each other and rebuild the capacity of this supply chain by : Identifying and removing impediments to the implementation of new construction and fabrication techniques and approaches for nuclear equipment, including system components and nuclear plants. Providing and facilitating detailed scientific-based studies on new approaches and technologies that will have positive impacts on the cost of building of nuclear plants. Analyzing and disseminating information about future nuclear fabrication technologies and how they could impact the North American and the International Nuclear Marketplace. Facilitating dialog and initiate alignment among fabricators, owners, trade associations, and government agencies. Supporting industry in helping to create a larger qualified nuclear supplier network. Acting as an unbiased technology resource to evaluate, develop, and demonstrate new manufacturing technologies. Creating welder and inspector training programs to help enable the necessary workforce for the upcoming construction work. Serving as a focal point for technology, policy, and politically interested parties to share ideas and concepts associated with fabrication across the nuclear industry. The report the objectives and summaries of the Nuclear Fabrication Consortium projects. Full technical reports for each of the projects have been submitted as well.« less

NAEP 1999 Long-Term Trend Technical Analysis Report: Three Decades of Student Performance. NCES 2005-484

ERIC Educational Resources Information Center

Allen, Nancy L.; McClellan, Catherine A.; Stoeckel, Joan J.

2005-01-01

This report provides an update to the technical analysis procedures documenting the 1996 National Assessment of Educational Progress (NAEP) as presented in "The NAEP 1996 Technical Report" (Allen, Carlson, and Zelenak, 1999). It describes how the 1999 long-term trend data were incorporated into the trend analyses. Since no national main…

Technologies for diagnosis and treatment of acute stroke

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fitch, J.P.

1998-02-09

From October 1994 to June 1997, a multidisciplinary team of scientists and engineers at Lawrence Livermore National Laboratory were funded through LDRD to develop and integrate technologies for diagnosis and treatment of acute stroke. The project was summarized in a Science and Technology Review article `Brain Attack` that appeared in June 1997 and again in the Center for Healthcare Technologies Report (UCRL-LR-124761). This article is the best overview of the project, epidemiology of stroke and technical progress. Most of the technical progress has been documented in conference papers and presentations and refereed journal articles. Additional technical publication can be expectedmore » as our remaining patent applications progress through the US Patent and Trademark Office. The purpose of this report is to provide an appropriate introduction and organization to the numerous publications so that interested readers can quickly find information. Because there is no documentation for the history of this project, this report provides a summary. It also provides the final status report for the LDRD funding.« less

The Johns Hopkins RTR Consortium: A Collaborative Approach to Advance Translational Science and Standardize Clinical Monitoring of Restorative Transplantation - Immunomodulation and Tolerance Induction after VCA using Biologic Agent (cTLA4-Ig) and Donor Bone Marrow Cells

DTIC Science & Technology

2014-10-01

group, Pig 22227, was due to a gastrointestinal bleed , related to either infectious gastroenteritis/colitis or stress ulcer formation. The third... upper extremity transplantation. Delays in progress and incomplete groups will be discussed in detail in Section 5 – Changes/Problems. Table 1...Implemented successfully first clinical protocol for upper extremity transplantation using donor bone marrow cell therapies and tacrolimus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacobs, G.K.

ORNL, through The Consortium for Research on Enhancing Carbon Sequestration in Terrestrial Ecosystems (CSiTE), collaborated with The Village Botanica, Inc. (VB) on a project investigating carbon sequestration in soils and commercial products from a new sustainable crop developed from perennial Hibiscus spp. Over 500 pre-treated samples were analyzed for soil carbon content. ORNL helped design a sampling scheme for soils during the planting phase of the project. Samples were collected and prepared by VB and analyzed for carbon content by ORNL. The project did not progress to a Phase II proposal because VB declined to prepare the required proposal.

JV Task 120 - Coal Ash Resources Research Consortium Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Debra Pflughoeft-Hassett; Loreal Heebink; David Hassett

2009-03-28

The Coal Ash Resources Research Consortium{reg_sign} (CARRC{reg_sign}, pronounced 'cars') is the core coal combustion product (CCP) research group at the Energy & Environmental Research Center (EERC). CARRC focuses on performing fundamental and applied scientific and engineering research emphasizing the environmentally safe, economical use of CCPs. CARRC member organizations, which include utilities and marketers, are key to developing industry-driven research in the area of CCP utilization and ensuring its successful application. The U.S. Department of Energy is a partner in CARRC through the EERC Jointly Sponsored Research Program, which provides matching funds for industrial member contributions and facilitates an increased levelmore » of effort in CARRC. CARRC tasks were designed to provide information on CCP performance, including environmental performance, engineering performance, favorable economics, and improved life cycle of products and projects. CARRC technical research tasks are developed based on member input and prioritization. CARRC special projects are developed with members and nonmembers to provide similar information and to support activities, including the assembly and interpretation of data, support for standards development and technology transfer, and facilitating product development and testing. CARRC activities from 2007 to 2009 included a range of research tasks, with primary work performed in laboratory tasks developed to answer specific questions or evaluate important fundamental properties of CCPs. The tasks were included in four categories: (1) Environmental Evaluations of CCPs; (2) Evaluation of Impacts on CCPs from Emission Controls; (3) Construction and Product-Related Activities; and (4) Technology Transfer and Maintenance Tasks. All tasks are designed to work toward achieving the CARRC overall goal and supporting objectives. The various tasks are coordinated in order to provide broad and useful technical data for CARRC members. Special projects provide an opportunity for non-CARRC members to sponsor specific research or technology transfer consistent with CARRC goals. This report covers CARRC activities from January 2007 through March 2009. These activities have been reported in CARRC Annual Reports and in member meetings over the past 2 years. CARRC continues to work with industry and various government agencies with its research, development, demonstration, and promotional activities nearing completion at the time of submission of this report. CARRC expects to continue its service to the coal ash industry in 2009 and beyond to work toward the common goal of advancing coal ash utilization by solving CCP-related technical issues and promoting the environmentally safe, technically sound, and economically viable management of these complex and changing materials.« less

Delivering the EarthScope Transportable Array as a Community Asset

NASA Astrophysics Data System (ADS)

Busby, R. W.; Woodward, R.; Simpson, D. W.; Hafner, K.

2009-12-01

The Transportable Array element of EarthScope/USArray is a culmination of years of coordination and planning for a large science initiative via the NSF MREFC program. US researchers and the IRIS Consortium conceived of the science objectives for a continental scale array and, together with the geodetic (PBO) and fault drilling (SAFOD) communities and NSF, successfully merged these scientific objectives with a compelling scientific and technical proposal, accompanied with the budget and schedule to accomplish it. The Transportable Array is now an efficient and exacting execution of an immense technical challenge that, by many measures, is yielding exciting science return, both expected and unanticipated. The technical facility is first-rate in its implementation, yet responsive to science objectives and discovery, actively engaging the community in discussion and new direction. The project is carried out by a core of dedicated and professional staff , guided and advised through considerable feedback from science users who have unprecedented access to high-quality data. This, in a sense, lets seismologists focus on research, rather than be administrators, drivers, shippers, battery mules, electronic technicians and radio hams. Now that USArray is operational, it is interesting to reflect on whether the TA, as a professionally executed project, could succeed as well if it were an independent endeavor, managed and operated outside of the resources developed and available through IRIS and its core programs. We detail how the support the USArray facility provides improves data accessibility and enhances interdisciplinary science. We suggest that the resources and community leadership provided by the IRIS Consortium, and the commitment to the principle of free and open data access, have been basic underpinnings for the success of the TA. This involvement of community-based, scientific leadership in the development of large facilities should be considered in planning future large Earth science or even basic science endeavors. The Global Seismographic Network provides another example where, with strong scientific leadership, the technical objectives have returned far more than expected results from all manner of application of new techniques to high quality data. Again, the key ingredient may be that the project oversight is driven by scientists with free and open access to data and broad and evolving expectations as to how the facility might be applied towards research objectives. Major projects must clearly follow defined plans and budgets; but, while it is important to have managers to motivate schedules and control costs, the energy, vigor and effort to optimize new measures and discover new applications derive from the insights and enthusiasm of the science community.

Inter-laboratory assessment of a harmonized zebrafish developmental toxicology assay - progress report on phase I.

PubMed

Gustafson, A-L; Stedman, D B; Ball, J; Hillegass, J M; Flood, A; Zhang, C X; Panzica-Kelly, J; Cao, J; Coburn, A; Enright, B P; Tornesi, M B; Hetheridge, M; Augustine-Rauch, K A

2012-04-01

This report provides a progress update of a consortium effort to develop a harmonized zebrafish developmental toxicity assay. Twenty non-proprietary compounds (10 animal teratogens and 10 animal non-teratogens) were evaluated blinded in 4 laboratories. Zebrafish embryos from pond-derived and cultivated strain wild types were exposed to the test compounds for 5 days and subsequently evaluated for lethality and morphological changes. Each of the testing laboratories achieved similar overall concordance to the animal data (60-70%). Subsequent optimization procedures to improve the overall concordance focused on compound formulation and test concentration adjustments, chorion permeation and number of replicates. These optimized procedures were integrated into a revised protocol and all compounds were retested in one lab using embryos from pond-derived zebrafish and achieved 85% total concordance. To further assess assay performance, a study of additional compounds is currently in progress at two laboratories using embryos from pond-derived and cultivated-strain wild type zebrafish. Copyright © 2011 Elsevier Inc. All rights reserved.

The DIAN-TU Next Generation Alzheimer’s prevention trial: adaptive design and disease progression model

PubMed Central

Bateman, Randall J.; Benzinger, Tammie L.; Berry, Scott; Clifford, David B.; Duggan, Cynthia; Fagan, Anne M.; Fanning, Kathleen; Farlow, Martin R.; Hassenstab, Jason; McDade, Eric M.; Mills, Susan; Paumier, Katrina; Quintana, Melanie; Salloway, Stephen P.; Santacruz, Anna; Schneider, Lon S.; Wang, Guoqiao; Xiong, Chengjie

2016-01-01

INTRODUCTION The Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) trial is an adaptive platform trial testing multiple drugs to slow or prevent the progression of Alzheimer’s disease in autosomal dominant Alzheimer’s disease (ADAD) families. With completion of enrollment of the first two drug arms, the DIAN-TU now plans to add new drugs to the platform, designated as the Next Generation Prevention Trial (NexGen). METHODS In collaboration with ADAD families, philanthropic organizations, academic leaders, the DIAN-TU Pharma Consortium, the NIH, and regulatory colleagues, the DIAN-TU developed innovative clinical study designs for the DIAN-TU NexGen trial. RESULTS Our expanded trials toolbox consists of a Disease Progression Model for ADAD, primary endpoint DIAN-TU cognitive performance composite, biomarker development, self-administered cognitive assessments, adaptive dose adjustments, and blinded data collection through the last participant completion. CONCLUSION These steps represent elements to improve efficacy of the adaptive platform trial and a continued effort to optimize prevention and treatment trials in ADAD. PMID:27583651

Proceedings: Computer Science and Data Systems Technical Symposium, volume 2

NASA Technical Reports Server (NTRS)

Larsen, Ronald L.; Wallgren, Kenneth

1985-01-01

Progress reports and technical updates of programs being performed by NASA centers are covered. Presentations in viewgraph form, along with abstracts, are included for topics in three catagories: computer science, data systems, and space station applications.

A study on operation efficiency evaluation based on firm's financial index and benchmark selection: take China Unicom as an example

NASA Astrophysics Data System (ADS)

Wu, Zu-guang; Tian, Zhan-jun; Liu, Hui; Huang, Rui; Zhu, Guo-hua

2009-07-01

Being the only listed telecom operators of A share market, China Unicom has always been attracted many institutional investors under the concept of 3G recent years,which itself is a great technical progress expectation.Do the institutional investors or the concept of technical progress have signficant effect on the improving of firm's operating efficiency?Though reviewing the documentary about operating efficiency we find that schoolars study this problem useing the regress analyzing based on traditional production function and data envelopment analysis(DEA) and financial index anayzing and marginal function and capital labor ratio coefficient etc. All the methods mainly based on macrodata. This paper we use the micro-data of company to evaluate the operating efficiency.Using factor analyzing based on financial index and comparing the factor score of three years from 2005 to 2007, we find that China Unicom's operating efficiency is under the averge level of benchmark corporates and has't improved under the concept of 3G from 2005 to 2007.In other words,institutional investor or the conception of technical progress expectation have faint effect on the changes of China Unicom's operating efficiency. Selecting benchmark corporates as post to evaluate the operating efficiency is a characteristic of this method ,which is basicallly sipmly and direct.This method is suit for the operation efficiency evaluation of agriculture listed companies because agriculture listed also face technical progress and marketing concept such as tax-free etc.

Decontamination Systems Information and Research Program. Quarterly technical progress report, January 1--March 31, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-05-01

West Virginia University (WVU) and the US DOE Morgantown Energy Technology Center (METC) entered into a Cooperative Agreement on August 29, 1992 entitled ``Decontamination Systems Information and Research Programs.`` Stipulated within the Agreement is the requirement that WVU submit to METC a series of Technical Progress Reports on a quarterly basis. This report comprises the first Quarterly Technical Progress Report for Year 2 of the Agreement. This report reflects the progress and/or efforts performed on the sixteen (16) technical projects encompassed by the Year 2 Agreement for the period of January 1 through March 31, 1994. In situ bioremediation ofmore » chlorinated organic solvents; Microbial enrichment for enhancing in-situ biodegradation of hazardous organic wastes; Treatment of volatile organic compounds (VOCs) using biofilters; Drain-enhanced soil flushing (DESF) for organic contaminants removal; Chemical destruction of chlorinated organic compounds; Remediation of hazardous sites with steam reforming; Soil decontamination with a packed flotation column; Use of granular activated carbon columns for the simultaneous removal of organics, heavy metals, and radionuclides; Monolayer and multilayer self-assembled polyion films for gas-phase chemical sensors; Compact mercuric iodide detector technology development; Evaluation of IR and mass spectrometric techniques for on-site monitoring of volatile organic compounds; A systematic database of the state of hazardous waste clean-up technologies; Dust control methods for insitu nuclear and hazardous waste handling; Winfield Lock and Dam remediation; and Socio-economic assessment of alternative environmental restoration technologies.« less

[Biomarkers and imaging for diagnosis and stratification of rheumatoid arthritis and spondylarthritis in the BMBF consortium ArthroMark].

PubMed

Häupl, T; Skapenko, A; Hoppe, B; Skriner, K; Burkhardt, H; Poddubnyy, D; Ohrndorf, S; Sewerin, P; Mansmann, U; Stuhlmüller, B; Schulze-Koops, H; Burmester, G-R

2018-05-01

Rheumatic diseases are among the most common chronic inflammatory disorders. Besides severe pain and progressive destruction of the joints, rheumatoid arthritis (RA), spondyloarthritides (SpA) and psoriatic arthritis (PsA) impair working ability, reduce quality of life and if treated insufficiently may enhance mortality. With the introduction of biologics to treat these diseases, the demand for biomarkers of early diagnosis and therapeutic stratification has been growing continuously. The main goal of the consortium ArthroMark is to identify new biomarkers and to apply modern imaging technologies for diagnosis, follow-up assessment and stratification of patients with RA, SpA and PsA. With the development of new biomarkers for these diseases, the ArthroMark project contributes to research in chronic diseases of the musculoskeletal system. The cooperation between different national centers will utilize site-specific resources, such as biobanks and clinical studies for sharing and gainful networking of individual core areas in biomarker analysis. Joint data management and harmonization of data assessment as well as best practice characterization of patients with new imaging technologies will optimize quality of marker validation.

Seizing the Future: How Ohio's Career-Technical Education Programs Fuse Academic Rigor and Real-World Experiences to Prepare Students for College and Careers

ERIC Educational Resources Information Center

Guarino, Heidi; Yoder, Shaun

2015-01-01

"Seizing the Future: How Ohio's Career and Technical Education Programs Fuse Academic Rigor and Real-World Experiences to Prepare Students for College and Work," demonstrates Ohio's progress in developing strong policies for career and technical education (CTE) programs to promote rigor, including college- and career-ready graduation…

Case Study on Technical and Vocational Education in Japan. Case Studies on Technical and Vocational Education in Asia and the Pacific.

ERIC Educational Resources Information Center

Iwamoto, Muneharu

In the course of Japan's economic progress, remarkable changes have occurred in the structure of industry and employment. Workers are in extremely short supply in such occupations as mining, manufacturing and construction, services, transportation and communication, sales, and professional and technical. On the basis of recommendations of the…

25 CFR 30.104 - What is the Secretary's definition of AYP?

Code of Federal Regulations, 2011 CFR

2011-04-01

... PROGRESS Defining Adequate Yearly Progress § 30.104 What is the Secretary's definition of AYP? The... accepted by the Department of Education. The Secretary is committed to providing technical assistance to a...

25 CFR 30.104 - What is the Secretary's definition of AYP?

Code of Federal Regulations, 2010 CFR

2010-04-01

... PROGRESS Defining Adequate Yearly Progress § 30.104 What is the Secretary's definition of AYP? The... accepted by the Department of Education. The Secretary is committed to providing technical assistance to a...

Building a community of practice in rural medical education: growing our own together.

PubMed

Longenecker, Randall L; Schmitz, David

2017-01-01

This article chronicles the rise, decline, and recent resurgence of rural training track residency programs (RTTs) in the USA over the past 30 years and the emergence of a healthy community of practice in rural medical education. This has occurred during a time in the USA when federal and state funding of graduate medical education has been relatively stagnant and the rules around finance and accreditation of rural programs have been challenging. Many of the early family residency programs developed in the 1970s included a curricular focus on rural practice. However, by the 1980s, these programs were not yet producing the desired numbers of rural physicians. In response, in 1986, Maudlin and others at the family medicine residency in Spokane developed the first 1-2 RTT in Colville, Washington. In the 1990s, and by 2000, early news of success led to a peak of 35 active programs. However, over the next decade these programs experienced significant hardship due to a lack of funding and a general decline in student interest in family medicine. By 2010, only 25 programs remained. In 2010, in an effort to sustain the 1-2 RTT as a national strategy in training physicians for rural practice, a federally funded consortium of individuals and programs established the RTT Technical Assistance program (RTT TA). Building on the pattern of peer support and collaboration set by earlier groups, the RTT TA consortium expanded the existing community of practice in rural medical education in support of RTTs. In-person meetings, peer consultation and visitation, coordinated efforts at student recruitment, and collaborative rural medical education research were all elements of the consortium's strategy. Rather than anchoring its efforts in medical schools or hospitals, this consortium engaged as partners a wider variety of stakeholders. This included physician educators still living and practicing in rural communities ('local experts'), rural medical educator peers, program directors, professional groups, academic units, governmental entities such as state offices of rural health, and national associations with a stake in rural medical education. The consortium has succeeded in (1) supporting established and new RTTs, (2) increasing medical student interest in these programs, and (3) demonstrating the effectiveness of this strategy through a minimum dataset and registry of RTT trainees. From a low of 21 programs in 2012, the number has grown to 32, accounting for a total of 68 positions in each year of training. The RTT Collaborative, the non-profit that has emerged as the sustainable product of that federal funding, is now supported by a national cooperative of participating rural programs and continues the work. Growing a community of practice in this fashion requires the organic building of relationships over time. The RTT TA consortium, and now the RTT Collaborative as a sustainable successor, have laid a strong foundation for community-engaged rural health professions education into the future - from each growing their own, to 'growing our own … together.

A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas.

PubMed

Attia, Steven; Kolesar, Jill; Mahoney, Michelle R; Pitot, Henry C; Laheru, Daniel; Heun, James; Huang, Wei; Eickhoff, Jens; Erlichman, Charles; Holen, Kyle D

2008-08-01

3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, Triapine) is a novel small molecule inhibitor of ribonucleotide reductase (RR) with clinical signs of activity in pancreatic cancer. Therefore, the Phase 2 Consortium (P2C) initiated a trial (two single stage studies with planned interim analysis) of 3-AP at 96 mg/m(2) intravenously days 1-4 and 15-18 of a 28-day cycle in both chemotherapy-naive and gemcitabine-refractory (GR) patients with advanced pancreatic cancer. The primary endpoint was survival at six months (chemotherapy-naive) and four months (GR). Secondary endpoints were toxicity, response, overall survival, time to progression and mechanistic studies. Fifteen patients were enrolled including one chemotherapy-naïve and 14 GR. The chemotherapy-naïve patient progressed during cycle 1 with grade 3 and 4 toxicities. Of 14 GR patients, seven received two cycles, six received one cycle and one received eight cycles. Progression precluded further treatment in 11 GR patients. Additionally, one died of an ileus in cycle 1 considered related to treatment and two stopped treatment due to toxicity. Five GR patients had grade 4 toxicities possibly related to 3-AP and six GR patients had grade 3 fatigue. Toxicities and lack of meaningful clinical benefit prompted early study closure. Four-month survival in GR patients was 21% (95% CI: 8-58%). Correlative studies confirmed that 3-AP increased the percentage of S-phase buccal mucosal cells, the presence of multidrug resistance gene polymorphisms appeared to predict leukopenia, and baseline pancreatic tumor RR M2 expression was low relative to other tumors treated with 3-AP. In conclusion, this regimen appears inactive against predominantly GR pancreatic cancer. RR M2 protein may not have a critical role in the malignant potential of pancreatic cancer.

A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas

PubMed Central

Attia, Steven; Kolesar, Jill; Mahoney, Michelle R.; Pitot, Henry C.; Laheru, Daniel; Heun, James; Huang, Wei; Eickhoff, Jens; Erlichman, Charles

2015-01-01

Summary 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, Triapine®) is a novel small molecule inhibitor of ribonucleotide reductase (RR) with clinical signs of activity in pancreatic cancer. Therefore, the Phase 2 Consortium (P2C) initiated a trial (two single stage studies with planned interim analysis) of 3-AP at 96 mg/m2 intravenously days 1–4 and 15–18 of a 28-day cycle in both chemotherapy-naive and gemcitabine-refractory (GR) patients with advanced pancreatic cancer. The primary endpoint was survival at six months (chemotherapy-naive) and four months (GR). Secondary endpoints were toxicity, response, overall survival, time to progression and mechanistic studies. Fifteen patients were enrolled including one chemotherapy-naïve and 14 GR. The chemotherapy-naïve patient progressed during cycle 1 with grade 3 and 4 toxicities. Of 14 GR patients, seven received two cycles, six received one cycle and one received eight cycles. Progression precluded further treatment in 11 GR patients. Additionally, one died of an ileus in cycle 1 considered related to treatment and two stopped treatment due to toxicity. Five GR patients had grade 4 toxicities possibly related to 3-AP and six GR patients had grade 3 fatigue. Toxicities and lack of meaningful clinical benefit prompted early study closure. Four-month survival in GR patients was 21% (95% CI: 8–58%). Correlative studies confirmed that 3-AP increased the percentage of S-phase buccal mucosal cells, the presence of multidrug resistance gene polymorphisms appeared to predict leukopenia, and baseline pancreatic tumor RR M2 expression was low relative to other tumors treated with 3-AP. In conclusion, this regimen appears inactive against predominantly GR pancreatic cancer. RR M2 protein may not have a critical role in the malignant potential of pancreatic cancer. PMID:18278438

ANNUAL REPORT, JULY 1, 1958

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1959-02-01

This annual report of Brookhaven National Laboratory describes its program and activities for the fiscal year 1958. The progress and trends of the research program are presented along with a description of the operational, service, and administrative activities of the Laboratory. The scientific and technical details of the many research and development activities are covered more fully in scientific and technical periodicals and in the quarterly scientific progress reports and other scientiflc reports of the Laboratory. A list of all publications for July 1, 1957 to June 30, 1958, is given. Status and progress are given in fields of physics,more » accelerator development, instrumentation, applied mathematics, chemistry, nuclear engineering, biology, and medical research. (For preceding period see BNL-462.) (W.D.M.)« less

On AIPS++, a new astronomical information processing system

NASA Technical Reports Server (NTRS)

Croes, G. A.

1992-01-01

The AIPS system that has served the needs of the radio astronomical community remarkably well during the last 15 years is showing signs of age and is being replaced by a more modern system, AIPS++. As the name implies, AIPS++ will be developed in a object oriented fashion and will use C++ as its main programming language. The work is being done by a consortium of seven organizations, with coordinated activities worldwide. After a review of the history of the project to this date from management, astronomical and technical viewpoints, and the current state of the project, the paper concentrates on the tradeoffs implied by the choice of implementation style and the lessons we have learned, good and bad.

Newborn Sequencing in Genomic Medicine and Public Health.

PubMed

Berg, Jonathan S; Agrawal, Pankaj B; Bailey, Donald B; Beggs, Alan H; Brenner, Steven E; Brower, Amy M; Cakici, Julie A; Ceyhan-Birsoy, Ozge; Chan, Kee; Chen, Flavia; Currier, Robert J; Dukhovny, Dmitry; Green, Robert C; Harris-Wai, Julie; Holm, Ingrid A; Iglesias, Brenda; Joseph, Galen; Kingsmore, Stephen F; Koenig, Barbara A; Kwok, Pui-Yan; Lantos, John; Leeder, Steven J; Lewis, Megan A; McGuire, Amy L; Milko, Laura V; Mooney, Sean D; Parad, Richard B; Pereira, Stacey; Petrikin, Joshua; Powell, Bradford C; Powell, Cynthia M; Puck, Jennifer M; Rehm, Heidi L; Risch, Neil; Roche, Myra; Shieh, Joseph T; Veeraraghavan, Narayanan; Watson, Michael S; Willig, Laurel; Yu, Timothy W; Urv, Tiina; Wise, Anastasia L

2017-02-01

The rapid development of genomic sequencing technologies has decreased the cost of genetic analysis to the extent that it seems plausible that genome-scale sequencing could have widespread availability in pediatric care. Genomic sequencing provides a powerful diagnostic modality for patients who manifest symptoms of monogenic disease and an opportunity to detect health conditions before their development. However, many technical, clinical, ethical, and societal challenges should be addressed before such technology is widely deployed in pediatric practice. This article provides an overview of the Newborn Sequencing in Genomic Medicine and Public Health Consortium, which is investigating the application of genome-scale sequencing in newborns for both diagnosis and screening. Copyright © 2017 by the American Academy of Pediatrics.

Progress on the Cluster Mission

NASA Technical Reports Server (NTRS)

Kivelson, Margaret; Khurana, Krishan; Acuna, Mario (Technical Monitor)

2002-01-01

Prof M. G. Kivelson and Dr. K. K. Khurana (UCLA (University of California, Los Angeles)) are co-investigators on the Cluster Magnetometer Consortium (CMC) that provided the fluxgate magnetometers and associated mission support for the Cluster Mission. The CMC designated UCLA as the site with primary responsibility for the inter-calibration of data from the four spacecraft and the production of fully corrected data critical to achieving the mission objectives. UCLA will also participate in the analysis and interpretation of the data. The UCLA group here reports its excellent progress in developing fully intra-calibrated data for large portions of the mission and an excellent start in developing inter-calibrated data for selected time intervals, especially extended intervals in August, 2001 on which a workshop held at ESTEC in March, 2002 focused. In addition, some scientific investigations were initiated and results were reported at meetings.

Towards a space-borne quantum gravity gradiometer: progress in laboratory demonstration

NASA Technical Reports Server (NTRS)

Yu, Nan; Kohel, James M.; Kellogg, James R.; Maleki, Lute

2005-01-01

This paper describes the working principles and technical benefits of atom-wave interferometer-based inertial sensors, and gives a progress report on the development of a quantum gravity gradiometer for space applications at JPL.

Technical Progress of the New Worlds Observer Mission

NASA Astrophysics Data System (ADS)

Lo, Amy; Noecker, C.; Cash, W.; NWO Study Team

2009-01-01

We report on the technical progress of the New Worlds Observer (NWO) mission concept. NWO is a two spacecraft mission that is capable of detecting and characterizing extra-solar, terrestrial planets and planetary systems. NWO consists of an external starshade and an UV-optical space telescope, flying in tandem. The starshade is a petal-shaped, opaque screen that creates an extremely dark shadow large enough to shade the telescope aperture from the target star. The NWO team has been addressing the top technology challenges of the concept, and report here our progress. We will present the current mission configuration best suited to address Terrestrial Planet Finding requirements, and highlight the technological breakthroughs that we have achieved this year. In particular, we will report on progress made in precision deployables for the large starshade, and the trajectory & alignment control system for NWO. We will also briefly highlight advances in understanding the starshade optical performance.

Minority Universities Systems Engineering (MUSE) Program at the University of Texas at El Paso

NASA Technical Reports Server (NTRS)

Robbins, Mary Clare; Usevitch, Bryan; Starks, Scott A.

1997-01-01

In 1995, The University of Texas at El Paso (UTEP) responded to the suggestion of NASA Jet Propulsion Laboratory (NASA JPL) to form a consortium comprised of California State University at Los Angeles (CSULA), North Carolina Agricultural and Technical University (NCAT), and UTEP from which developed the Minority Universities Systems Engineering (MUSE) Program. The mission of this consortium is to develop a unique position for minority universities in providing the nation's future system architects and engineers as well as enhance JPL's system design capability. The goals of this collaboration include the development of a system engineering curriculum which includes hands-on project engineering and design experiences. UTEP is in a unique position to take full advantage of this program since UTEP has been named a Model Institution for Excellence (MIE) by the National Science Foundation. The purpose of MIE is to produce leaders in Science, Math, and Engineering. Furthermore, UTEP has also been selected as the site for two new centers including the Pan American Center for Earth and Environmental Sciences (PACES) directed by Dr. Scott Starks and the FAST Center for Structural Integrity of Aerospace Systems directed by Dr. Roberto Osegueda. The UTEP MUSE Program operates under the auspices of the PACES Center.

A Novel Lung Disease Phenotype Adjusted for Mortality Attrition for Cystic Fibrosis Genetic Modifier Studies

PubMed Central

Taylor, Chelsea; Commander, Clayton W.; Collaco, Joseph M.; Strug, Lisa J.; Li, Weili; Wright, Fred A.; Webel, Aaron D.; Pace, Rhonda G.; Stonebraker, Jaclyn R.; Naughton, Kathleen; Dorfman, Ruslan; Sandford, Andrew; Blackman, Scott M.; Berthiaume, Yves; Paré, Peter; Drumm, Mitchell L.; Zielenski, Julian; Durie, Peter; Cutting, Garry R.; Knowles, Michael R.; Corey, Mary

2011-01-01

SUMMARY Genetic studies of lung disease in Cystic Fibrosis are hampered by the lack of a severity measure that accounts for chronic disease progression and mortality attrition. Further, combining analyses across studies requires common phenotypes that are robust to study design and patient ascertainment. Using data from the North American Cystic Fibrosis Modifier Consortium (Canadian Consortium for CF Genetic Studies, Johns Hopkins University CF Twin and Sibling Study, and University of North Carolina/Case Western Reserve University Gene Modifier Study), the authors calculated age-specific CF percentile values of FEV1 which were adjusted for CF age-specific mortality data. The phenotype was computed for 2061 patients representing the Canadian CF population, 1137 extreme phenotype patients in the UNC/Case Western study, and 1323 patients from multiple CF sib families in the CF Twin and Sibling Study. Despite differences in ascertainment and median age, our phenotype score was distributed in all three samples in a manner consistent with ascertainment differences, reflecting the lung disease severity of each individual in the underlying population. The new phenotype score was highly correlated with the previously recommended complex phenotype, but the new phenotype is more robust for shorter follow-up and for extreme ages. A disease progression and mortality adjusted phenotype reduces the need for stratification or additional covariates, increasing statistical power and avoiding possible distortions. This approach will facilitate large scale genetic and environmental epidemiological studies which will provide targeted therapeutic pathways for the clinical benefit of patients with CF. PMID:21462361

Accelerating the Development of 21st-Century Toxicology: Outcome of a Human Toxicology Project Consortium Workshop

PubMed Central

Stephens, Martin L.; Barrow, Craig; Andersen, Melvin E.; Boekelheide, Kim; Carmichael, Paul L.; Holsapple, Michael P.; Lafranconi, Mark

2012-01-01

The U.S. National Research Council (NRC) report on “Toxicity Testing in the 21st century” calls for a fundamental shift in the way that chemicals are tested for human health effects and evaluated in risk assessments. The new approach would move toward in vitro methods, typically using human cells in a high-throughput context. The in vitro methods would be designed to detect significant perturbations to “toxicity pathways,” i.e., key biological pathways that, when sufficiently perturbed, lead to adverse health outcomes. To explore progress on the report’s implementation, the Human Toxicology Project Consortium hosted a workshop on 9–10 November 2010 in Washington, DC. The Consortium is a coalition of several corporations, a research institute, and a non-governmental organization dedicated to accelerating the implementation of 21st-century Toxicology as aligned with the NRC vision. The goal of the workshop was to identify practical and scientific ways to accelerate implementation of the NRC vision. The workshop format consisted of plenary presentations, breakout group discussions, and concluding commentaries. The program faculty was drawn from industry, academia, government, and public interest organizations. Most presentations summarized ongoing efforts to modernize toxicology testing and approaches, each with some overlap with the NRC vision. In light of these efforts, the workshop identified recommendations for accelerating implementation of the NRC vision, including greater strategic coordination and planning across projects (facilitated by a steering group), the development of projects that test the proof of concept for implementation of the NRC vision, and greater outreach and communication across stakeholder communities. PMID:21948868

Developing the Safety of Atrial Fibrillation Ablation Registry Initiative (SAFARI) as a collaborative pan-stakeholder critical path registry model: a Cardiac Safety Research Consortium "Incubator" Think Tank.

PubMed

Al-Khatib, Sana M; Calkins, Hugh; Eloff, Benjamin C; Kowey, Peter; Hammill, Stephen C; Ellenbogen, Kenneth A; Marinac-Dabic, Danica; Waldo, Albert L; Brindis, Ralph G; Wilbur, David J; Jackman, Warren M; Yaross, Marcia S; Russo, Andrea M; Prystowsky, Eric; Varosy, Paul D; Gross, Thomas; Pinnow, Ellen; Turakhia, Mintu P; Krucoff, Mitchell W

2010-10-01

Although several randomized clinical trials have demonstrated the safety and efficacy of catheter ablation of atrial fibrillation (AF) in experienced centers, the outcomes of this procedure in routine clinical practice and in patients with persistent and long-standing persistent AF remain uncertain. Brisk adoption of this therapy by physicians with diverse training and experience highlights potential concerns regarding the safety and effectiveness of this procedure. Some of these concerns could be addressed by a national registry of AF ablation procedures such as the Safety of Atrial Fibrillation Ablation Registry Initiative that was initially proposed at a Cardiac Safety Research Consortium Think Tank meeting in April 2009. In January 2010, the Cardiac Safety Research Consortium, in collaboration with the Duke Clinical Research Institute, the US Food and Drug Administration, the American College of Cardiology, and the Heart Rhythm Society, held a follow-up meeting of experts in the field to review the construct and progress to date. Other participants included the National Heart, Lung, and Blood Institute; the Centers for Medicare and Medicaid Services; the Agency for Healthcare Research and Quality; the AdvaMed AF working group; and additional industry representatives. This article summarizes the discussions that occurred at the meeting of the state of the Safety of Atrial Fibrillation Ablation Registry Initiative, the identification of a clear pathway for its implementation, and the exploration of solutions to potential issues in the execution of this registry. Copyright © 2010 Mosby, Inc. All rights reserved.

The Spanish biology/disease initiative within the human proteome project: Application to rheumatic diseases.

PubMed

Ruiz-Romero, Cristina; Calamia, Valentina; Albar, Juan Pablo; Casal, José Ignacio; Corrales, Fernando J; Fernández-Puente, Patricia; Gil, Concha; Mateos, Jesús; Vivanco, Fernando; Blanco, Francisco J

2015-09-08

The Spanish Chromosome 16 consortium is integrated in the global initiative Human Proteome Project, which aims to develop an entire map of the proteins encoded following a gene-centric strategy (C-HPP) in order to make progress in the understanding of human biology in health and disease (B/D-HPP). Chromosome 16 contains many genes encoding proteins involved in the development of a broad range of diseases, which have a significant impact on the health care system. The Spanish HPP consortium has developed a B/D platform with five programs focused on selected medical areas: cancer, obesity, cardiovascular, infectious and rheumatic diseases. Each of these areas has a clinical leader associated to a proteomic investigator with the responsibility to get a comprehensive understanding of the proteins encoded by Chromosome 16 genes. Proteomics strategies have enabled great advances in the area of rheumatic diseases, particularly in osteoarthritis, with studies performed on joint cells, tissues and fluids. In this manuscript we describe how the Spanish HPP-16 consortium has developed a B/D platform with five programs focused on selected medical areas: cancer, obesity, cardiovascular, infectious and rheumatic diseases. Each of these areas has a clinical leader associated to a proteomic investigator with the responsibility to get a comprehensive understanding of the proteins encoded by Chromosome 16 genes. We show how the Proteomic strategy has enabled great advances in the area of rheumatic diseases, particularly in osteoarthritis, with studies performed on joint cells, tissues and fluids. This article is part of a Special Issue entitled: HUPO 2014. Copyright © 2015 Elsevier B.V. All rights reserved.

PanScan, the Pancreatic Cancer Cohort Consortium, and the Pancreatic Cancer Case-Control Consortium

Cancer.gov

The Pancreatic Cancer Cohort Consortium consists of more than a dozen prospective epidemiologic cohort studies within the NCI Cohort Consortium, whose leaders work together to investigate the etiology and natural history of pancreatic cancer.

Amarillo National Resource Center for Plutonium. Quarterly technical progress report, May 1, 1997--July 31, 1997

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Progress summaries are provided from the Amarillo National Center for Plutonium. Programs include the plutonium information resource center, environment, public health, and safety, education and training, nuclear and other material studies.

Urology technical and non-technical skills development: the emerging role of simulation.

PubMed

Rashid, Prem; Gianduzzo, Troy R J

2016-04-01

To review the emerging role of technical and non-technical simulation in urological education and training. A review was conducted to examine the current role of simulation in urology training. A PUBMED search of the terms 'urology training', 'urology simulation' and 'urology education' revealed 11,504 titles. Three hundred and fifty-seven abstracts were identified as English language, peer reviewed papers pertaining to the role of simulation in urology and related topics. Key papers were used to explore themes. Some cross-referenced papers were also included. There is an ongoing need to ensure that training time is efficiently utilised while ensuring that optimal technical and non-technical skills are achieved. Changing working conditions and the need to minimise patient harm by inadvertent errors must be taken into account. Simulation models for specific technical aspects have been the mainstay of graduated step-wise low and high fidelity training. Whole scenario environments as well as non-technical aspects can be slowly incorporated into the curriculum. Doing so should also help define what have been challenging competencies to teach and evaluate. Dedicated time, resources and trainer up-skilling are important. Concurrent studies are needed to help evaluate the effectiveness of introducing step-wise simulation for technical and non-technical competencies. Simulation based learning remains the best avenue of progressing surgical education. Technical and non-technical simulation could be used in the selection process. There are good economic, logistic and safety reasons to pursue the process of ongoing development of simulation co-curricula. While the role of simulation is assured, its progress will depend on a structured program that takes advantage of what can be delivered via this medium. Overall, simulation can be developed further for urological training programs to encompass technical and non-technical skill development at all stages, including recertification. © 2015 The Authors BJU International © 2015 BJU International Published by John Wiley & Sons Ltd.

A Portfolio Analysis Tool for Measuring NASAs Aeronautics Research Progress toward Planned Strategic Outcomes

NASA Technical Reports Server (NTRS)

Tahmasebi, Farhad; Pearce, Robert

2016-01-01

Description of a tool for portfolio analysis of NASA's Aeronautics research progress toward planned community strategic Outcomes is presented. The strategic planning process for determining the community Outcomes is also briefly described. Stakeholder buy-in, partnership performance, progress of supporting Technical Challenges, and enablement forecast are used as the criteria for evaluating progress toward Outcomes. A few illustrative examples are also presented.

An approach to knowledge structuring for advanced phases of the Technical and Management Information System (TMIS)

NASA Technical Reports Server (NTRS)

Goranson, H. T.

1986-01-01

The Technical and Management Information System (TMIS) must employ on enlightened approach to its object structure, but basic issues in conceptual structuring remain to be resolved. Sirius outlines the necessary agenda and reports on progress toward solutions.

48 CFR 752.7035 - Public notices.

Code of Federal Regulations, 2011 CFR

2011-10-01

... notices. The following clause is for use when the cognizant technical office determines that the contract... to time, to announce progress and accomplishments. Press releases or other public notices should... cognizant technical officer and to USAID's Legislative and Public Affairs (LPA) as far in advance of release...

14 CFR 1260.71 - Supplements and renewals.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., continued research relevance, and progress made by the recipient. (2) To insure uninterrupted programs, the technical office should forward to the grant office a completed award package, including a funded procurement request, technical evaluation of the proposed budget, and other support documentation, at least 29...

[A technical modification of the use of Dwyer's equipment].

PubMed

Carlioz, H; Damsin, J P

1991-01-01

Dwyer's technique for correction and anterior fusion of the spine was improved by using lockers at the level of each screw. So, like with the Zielke's technic this procedure allowed a global progressive and controllable correction and a real derotation of the spine.

Northern New Jersey Nursing Education Consortium: a partnership for graduate nursing education.

PubMed

Quinless, F W; Levin, R F

1998-01-01

The purpose of this article is to describe the evolution and implementation of the Northern New Jersey Nursing Education consortium--a consortium of seven member institutions established in 1992. Details regarding the specific functions of the consortium relative to cross-registration of students in graduate courses, financial disbursement of revenue, faculty development activities, student services, library privileges, and institutional research review board mechanisms are described. The authors also review the administrative organizational structure through which the work conducted by the consortium occurs. Both the advantages and disadvantages of such a graduate consortium are explored, and specific examples of recent potential and real conflicts are fully discussed. The authors detail governance and structure of the consortium as a potential model for replication in other environments.

A systematic assessment of the state of hazardous waste clean-up technologies. Quarterly technical progress report, April 1--June 30, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berg, M.T.; Reed, B.E.; Gabr, M.

1993-07-01

West Virginia University (WVU) and the US DOE Morgantown Energy Technology Center (METC) entered into a Cooperative Agreement on August 29, 1992 entitled ``Decontamination Systems Information and Research Programs.`` Stipulated within the Agreement is the requirement that WVU submit to METC a series of Technical Progress Report for Year 1 of the Agreement. This report reflects the progress and/or efforts performed on the following nine technical projects encompassed by the Year 1 Agreement for the period of April 1 through June 30, 1993: Systematic assessment of the state of hazardous waste clean-up technologies; site remediation technologies -- drain-enhanced soil flushingmore » (DESF) for organic contaminants removal; site remediation technologies -- in situ bioremediation of organic contaminants; excavation systems for hazardous waste sites; chemical destruction of polychlorinated biphenyls; development of organic sensors -- monolayer and multilayer self-assembled films for chemical sensors; Winfield lock and dam remediation; Assessments of Technologies for hazardous waste site remediation -- non-treatment technologies and pilot scale test facility implementation; and remediation of hazardous sites with stream reforming.« less

10 CFR 603.515 - Qualification of a consortium.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Recipient Qualification § 603.515 Qualification of a consortium. (a) A consortium that... under the agreement. (b) If the prospective recipient of a TIA is a consortium that is not formally...

10 CFR 603.515 - Qualification of a consortium.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Recipient Qualification § 603.515 Qualification of a consortium. (a) A consortium that... under the agreement. (b) If the prospective recipient of a TIA is a consortium that is not formally...

10 CFR 603.515 - Qualification of a consortium.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Pre-Award Business Evaluation Recipient Qualification § 603.515 Qualification of a consortium. (a) A consortium that... under the agreement. (b) If the prospective recipient of a TIA is a consortium that is not formally...

25 CFR 1000.33 - What amount of funding is to be removed from the Consortium's AFA for the withdrawing Tribe?

Code of Federal Regulations, 2010 CFR

2010-04-01

... Participation in Tribal Self-Governance Withdrawal from A Consortium Annual Funding Agreement § 1000.33 What... the Consortium agreement is reduced if: (1) The Consortium, Tribe, OSG, and bureau agree it is...

Validating new diagnostic imaging criteria for primary progressive aphasia via anatomical likelihood estimation meta-analyses.

PubMed

Bisenius, S; Neumann, J; Schroeter, M L

2016-04-01

Recently, diagnostic clinical and imaging criteria for primary progressive aphasia (PPA) have been revised by an international consortium (Gorno-Tempini et al. Neurology 2011;76:1006-14). The aim of this study was to validate the specificity of the new imaging criteria and investigate whether different imaging modalities [magnetic resonance imaging (MRI) and fluorodeoxyglucose positron emission tomography (FDG-PET)] require different diagnostic subtype-specific imaging criteria. Anatomical likelihood estimation meta-analyses were conducted for PPA subtypes across a large cohort of 396 patients: firstly, across MRI studies for each of the three PPA subtypes followed by conjunction and subtraction analyses to investigate the specificity, and, secondly, by comparing results across MRI vs. FDG-PET studies in semantic dementia and progressive nonfluent aphasia. Semantic dementia showed atrophy in temporal, fusiform, parahippocampal gyri, hippocampus, and amygdala, progressive nonfluent aphasia in left putamen, insula, middle/superior temporal, precentral, and frontal gyri, logopenic progressive aphasia in middle/superior temporal, supramarginal, and dorsal posterior cingulate gyri. Results of the disease-specific meta-analyses across MRI studies were disjunct. Similarly, atrophic and hypometabolic brain networks were regionally dissociated in both semantic dementia and progressive nonfluent aphasia. In conclusion, meta-analyses support the specificity of new diagnostic imaging criteria for PPA and suggest that they should be specified for each imaging modality separately. © 2016 EAN.

Progress, innovation and regulatory science in drug development: the politics of international standard-setting.

PubMed

Abraham, John; Reed, Tim

2002-06-01

This paper examines international standard-setting in the toxicology of pharmaceuticals during the 1990s, which has involved both the pharmaceutical industry and regulatory agencies in an organization known as the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The analysis shows that the relationships between innovation, regulatory science and 'progress' may be more complex and controversial than is often assumed. An assessment of the ICH's claims about the implications of 'technical' harmonization of drug-testing standards for the maintenance of drug safety, via toxicological testing, and the delivery of therapeutic progress, via innovation, is presented. By demonstrating that there is not a technoscientific validity for these claims, it is argued that, within the ICH, a discourse of technological innovation and scientific progress has been used by regulatory agencies and prominent parts of the transnational pharmaceutical industry to legitimize the lowering and loosening of toxicological standards for drug testing. The mobilization and acceptance of this discourse are shown to be pivotal to the ICH's transformation of reductions in safety standards, which are apparently against the interests of patients and public health, into supposed therapeutic benefits derived from promises of greater access to more innovative drug products. The evidence suggests that it is highly implausible that these reductions in the standards of regulatory toxicology are consistent with therapeutic progress for patients, and highlights a worrying aspect embedded in the 'technical trajectories' of regulatory science.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morrison, Joel

The United States has more oil and gas wells than any other country. As of December 31, 2004, there were more than half a million producing oil wells in the United States. That is more than three times the combined total for the next three leaders: China, Canada, and Russia. The Stripper Well Consortium (SWC) is a partnership that includes domestic oil and gas producers, service and supply companies, trade associations, academia, the Department of Energy’s Strategic Center for Natural Gas and Oil (SCNGO) at the National Energy Technology Laboratory (NETL), and the New York State Energy Research and Developmentmore » Authority (NYSERDA). The Consortium was established in 2000. This report serves as a final technical report for the SWC activities conducted over the May 1, 2004 to December 1, 2011 timeframe. During this timeframe, the SWC worked with 173 members in 29 states and three international countries, to focus on the development of new technologies to benefit the U.S. stripper well industry. SWC worked with NETL to develop a nationwide request-for-proposal (RFP) process to solicit proposals from the U.S. stripper well industry to develop and/or deploy new technologies that would assist small producers in improving the production performance of their stripper well operations. SWC conducted eight rounds of funding. A total of 132 proposals were received. The proposals were compiled and distributed to an industry-driven SWC executive council and program sponsors for review. Applicants were required to make a formal technical presentation to the SWC membership, executive council, and program sponsors. After reviewing the proposals and listening to the presentations, the executive council made their funding recommendations to program sponsors. A total of 64 projects were selected for funding, of which 59 were fully completed. Penn State then worked with grant awardees to issue a subcontract for their approved work. SWC organized and hosted a total of 14 meetings dedicated to technology transfer to showcase and review SWC-funded technology. The workshops were open to the stripper well industry.« less

The Consortium of Advanced Residential Buildings (CARB) - A Building America Energy Efficient Housing Partnership

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robb Aldrich; Lois Arena; Dianne Griffiths

2010-12-31

This final report summarizes the work conducted by the Consortium of Advanced Residential Buildings (CARB) (http://www.carb-swa.com/), one of the 'Building America Energy Efficient Housing Partnership' Industry Teams, for the period January 1, 2008 to December 31, 2010. The Building America Program (BAP) is part of the Department of Energy (DOE), Energy Efficiency and Renewable Energy, Building Technologies Program (BTP). The long term goal of the BAP is to develop cost effective, production ready systems in five major climate zones that will result in zero energy homes (ZEH) that produce as much energy as they use on an annual basis bymore » 2020. CARB is led by Steven Winter Associates, Inc. with Davis Energy Group, Inc. (DEG), MaGrann Associates, and Johnson Research, LLC as team members. In partnership with our numerous builders and industry partners, work was performed in three primary areas - advanced systems research, prototype home development, and technical support for communities of high performance homes. Our advanced systems research work focuses on developing a better understanding of the installed performance of advanced technology systems when integrated in a whole-house scenario. Technology systems researched included: - High-R Wall Assemblies - Non-Ducted Air-Source Heat Pumps - Low-Load HVAC Systems - Solar Thermal Water Heating - Ventilation Systems - Cold-Climate Ground and Air Source Heat Pumps - Hot/Dry Climate Air-to-Water Heat Pump - Condensing Boilers - Evaporative condensers - Water Heating CARB continued to support several prototype home projects in the design and specification phase. These projects are located in all five program climate regions and most are targeting greater than 50% source energy savings over the Building America Benchmark home. CARB provided technical support and developed builder project case studies to be included in near-term Joule Milestone reports for the following community scale projects: - SBER Overlook at Clipper Mill (mixed, humid climate) - William Ryan Homes - Tampa (hot, humid climate).« less

7 CFR 1944.541 - Reporting requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) PROGRAM REGULATIONS (CONTINUED) HOUSING Technical and Supervisory Assistance Grants § 1944.541 Reporting... District Director to determine satisfactory progress. The District Director will work with the grantee to... five working days of receipt. (1) If the reports indicate satisfactory progress, the State Director...

The magnetohydrodynamics coal-fired flow facility

NASA Astrophysics Data System (ADS)

1995-01-01

In this quarterly technical progress report, UTSI reports on the status of a multitask contract to develop the technology for the steam bottoming portion of a MHD Steam Combined Cycle Power Plant. The report describes the facility maintenance and environmental work completed, status of completing technical reports and certain key administrative actions occurring during the quarter. With program resources at a minimum to closeout the MHD program, no further testing occurred during the quarter, but the DOE CFFF facility was maintained in a standby status with winterization, preventive maintenance and repairs accomplished as needed. Plans and preparations progressed for environmental actions needed at the site to investigate and characterize the groundwater and for removal/disposal of asbestos in the cooling tower. Work continued to progress on archiving the results of the MHD program.

The autism sequencing consortium: large-scale, high-throughput sequencing in autism spectrum disorders.

PubMed

Buxbaum, Joseph D; Daly, Mark J; Devlin, Bernie; Lehner, Thomas; Roeder, Kathryn; State, Matthew W

2012-12-20

Research during the past decade has seen significant progress in the understanding of the genetic architecture of autism spectrum disorders (ASDs), with gene discovery accelerating as the characterization of genomic variation has become increasingly comprehensive. At the same time, this research has highlighted ongoing challenges. Here we address the enormous impact of high-throughput sequencing (HTS) on ASD gene discovery, outline a consensus view for leveraging this technology, and describe a large multisite collaboration developed to accomplish these goals. Similar approaches could prove effective for severe neurodevelopmental disorders more broadly. Copyright © 2012 Elsevier Inc. All rights reserved.

Background research in support of the new grant proposal: Research consortium for X-ray topography on line X-19 at NSLS

NASA Astrophysics Data System (ADS)

Bilello, J. C.

1983-11-01

The status of the construction and installation of components of the synchrotron topography station is reported as well as progress in the development of hardware for interfacing and software for interactively controlling the 13 motors which automate the facility. Research focuses on the problem of X-ray optics and on techniques for applying topography to materials science. There is colaboration with other researchers in studying the nature of brittle fracture of refractory metals and in interpreting contact in the vicinity of crack tips.

Amarillo National Resource Center for plutonium. Work plan progress report, November 1, 1995--January 31, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cluff, D.

1996-04-01

The Center operates under a cooperative agreement between DOE and the State of Texas and is directed and administered by an education consortium. Its programs include developing peaceful uses for the materials removed from dismantled weapons, studying effects of nuclear materials on environment and public health, remedying contaminated soils and water, studying storage, disposition, and transport of Pu, HE, and other hazardous materials removed from weapons, providing research and counsel to US in carrying out weapons reductions in cooperation with Russia, and conducting a variety of education and training programs.

Fragment-based hit identification: thinking in 3D.

PubMed

Morley, Andrew D; Pugliese, Angelo; Birchall, Kristian; Bower, Justin; Brennan, Paul; Brown, Nathan; Chapman, Tim; Drysdale, Martin; Gilbert, Ian H; Hoelder, Swen; Jordan, Allan; Ley, Steven V; Merritt, Andy; Miller, David; Swarbrick, Martin E; Wyatt, Paul G

2013-12-01

The identification of high-quality hits during the early phases of drug discovery is essential if projects are to have a realistic chance of progressing into clinical development and delivering marketed drugs. As the pharmaceutical industry goes through unprecedented change, there are increasing opportunities to collaborate via pre-competitive networks to marshal multifunctional resources and knowledge to drive impactful, innovative science. The 3D Fragment Consortium is developing fragment-screening libraries with enhanced 3D characteristics and evaluating their effect on the quality of fragment-based hit identification (FBHI) projects. Copyright © 2013 Elsevier Ltd. All rights reserved.

GPHS-RTGs in support of the Cassini RTG Program

NASA Astrophysics Data System (ADS)

1995-04-01

The technical progress achieved during the period 26 Sep. 1994 - 2 Apr. 1995 on Contract DE-AC03-91SF-18852 Radioisotope Thermoelectric Generators and Ancillary Activities is described herein. Monthly technical activity for the period 27 Feb. - 2 Apr. 1995 is included in this progress report. The report addresses tasks, including: spacecraft integration and liaison; engineering support; safety; qualified unicouple production; ETG fabrication, assembly, and test; ground support equipment; RTG shipping and launch support; designs, reviews, and mission applications; project management, quality assurance, reliability, contract changes, CAGO acquisition (operating funds), and CAGO maintenance and repair; and CAGO acquisition (capital funds).

25 CFR 1000.310 - What information must the Tribe's/Consortium's response contain?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false What information must the Tribe's/Consortium's response... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reassumption § 1000.310 What information must the Tribe's/Consortium's response contain? (a) The Tribe's/Consortium's response must indicate the specific measures that...

25 CFR 1000.255 - May a Tribe/Consortium reallocate funds among construction programs?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false May a Tribe/Consortium reallocate funds among... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.255 May a Tribe/Consortium reallocate funds among construction programs? Yes, a Tribe/Consortium may reallocate funds among construction...

25 CFR 1000.310 - What information must the Tribe's/Consortium's response contain?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false What information must the Tribe's/Consortium's response... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reassumption § 1000.310 What information must the Tribe's/Consortium's response contain? (a) The Tribe's/Consortium's response must indicate the specific measures that...

25 CFR 1000.255 - May a Tribe/Consortium reallocate funds among construction programs?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false May a Tribe/Consortium reallocate funds among... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.255 May a Tribe/Consortium reallocate funds among construction programs? Yes, a Tribe/Consortium may reallocate funds among construction...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development Regulations Relating to Housing and... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

24 CFR 943.124 - What elements must a consortium agreement contain?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false What elements must a consortium agreement contain? 943.124 Section 943.124 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND... elements must a consortium agreement contain? (a) The consortium agreement among the participating PHAs...

Concentrating solar power (CSP) power cycle improvements through application of advanced materials

NASA Astrophysics Data System (ADS)

Siefert, John A.; Libby, Cara; Shingledecker, John

2016-05-01

Concentrating solar power (CSP) systems with thermal energy storage (TES) capability offer unique advantages to other renewable energy technologies in that solar radiation can be captured and stored for utilization when the sun is not shining. This makes the technology attractive as a dispatchable resource, and as such the Electric Power Research Institute (EPRI) has been engaged in research and development activities to understand and track the technology, identify key technical challenges, and enable improvements to meet future cost and performance targets to enable greater adoption of this carbon-free energy resource. EPRI is also involved with technically leading a consortium of manufacturers, government labs, and research organizations to enable the next generation of fossil fired power plants with advanced ultrasupercritical (A-USC) steam temperatures up to 760°C (1400°F). Materials are a key enabling technology for both of these seemingly opposed systems. This paper discusses how major strides in structural materials for A-USC fossil fired power plants may be translated into improved CSP systems which meet target requirements.

A Novel Cross-Disciplinary Multi-Institute Approach to Translational Cancer Research: Lessons Learned from Pennsylvania Cancer Alliance Bioinformatics Consortium (PCABC)

PubMed Central

Patel, Ashokkumar A.; Gilbertson, John R.; Showe, Louise C.; London, Jack W.; Ross, Eric; Ochs, Michael F.; Carver, Joseph; Lazarus, Andrea; Parwani, Anil V.; Dhir, Rajiv; Beck, J. Robert; Liebman, Michael; Garcia, Fernando U.; Prichard, Jeff; Wilkerson, Myra; Herberman, Ronald B.; Becich, Michael J.

2007-01-01

Background: The Pennsylvania Cancer Alliance Bioinformatics Consortium (PCABC, http://www.pcabc.upmc.edu) is one of the first major project-based initiatives stemming from the Pennsylvania Cancer Alliance that was funded for four years by the Department of Health of the Commonwealth of Pennsylvania. The objective of this was to initiate a prototype biorepository and bioinformatics infrastructure with a robust data warehouse by developing a statewide data model (1) for bioinformatics and a repository of serum and tissue samples; (2) a data model for biomarker data storage; and (3) a public access website for disseminating research results and bioinformatics tools. The members of the Consortium cooperate closely, exploring the opportunity for sharing clinical, genomic and other bioinformatics data on patient samples in oncology, for the purpose of developing collaborative research programs across cancer research institutions in Pennsylvania. The Consortium’s intention was to establish a virtual repository of many clinical specimens residing in various centers across the state, in order to make them available for research. One of our primary goals was to facilitate the identification of cancer-specific biomarkers and encourage collaborative research efforts among the participating centers. Methods: The PCABC has developed unique partnerships so that every region of the state can effectively contribute and participate. It includes over 80 individuals from 14 organizations, and plans to expand to partners outside the State. This has created a network of researchers, clinicians, bioinformaticians, cancer registrars, program directors, and executives from academic and community health systems, as well as external corporate partners - all working together to accomplish a common mission. The various sub-committees have developed a common IRB protocol template, common data elements for standardizing data collections for three organ sites, intellectual property/tech transfer agreements, and material transfer agreements that have been approved by each of the member institutions. This was the foundational work that has led to the development of a centralized data warehouse that has met each of the institutions’ IRB/HIPAA standards. Results: Currently, this “virtual biorepository” has over 58,000 annotated samples from 11,467 cancer patients available for research purposes. The clinical annotation of tissue samples is either done manually over the internet or semi-automated batch modes through mapping of local data elements with PCABC common data elements. The database currently holds information on 7188 cases (associated with 9278 specimens and 46,666 annotated blocks and blood samples) of prostate cancer, 2736 cases (associated with 3796 specimens and 9336 annotated blocks and blood samples) of breast cancer and 1543 cases (including 1334 specimens and 2671 annotated blocks and blood samples) of melanoma. These numbers continue to grow, and plans to integrate new tumor sites are in progress. Furthermore, the group has also developed a central web-based tool that allows investigators to share their translational (genomics/proteomics) experiment data on research evaluating potential biomarkers via a central location on the Consortium’s web site. Conclusions: The technological achievements and the statewide informatics infrastructure that have been established by the Consortium will enable robust and efficient studies of biomarkers and their relevance to the clinical course of cancer. Studies resulting from the creation of the Consortium may allow for better classification of cancer types, more accurate assessment of disease prognosis, a better ability to identify the most appropriate individuals for clinical trial participation, and better surrogate markers of disease progression and/or response to therapy. PMID:19455246

Benchmark Problems Used to Assess Computational Aeroacoustics Codes

NASA Technical Reports Server (NTRS)

Dahl, Milo D.; Envia, Edmane

2005-01-01

The field of computational aeroacoustics (CAA) encompasses numerical techniques for calculating all aspects of sound generation and propagation in air directly from fundamental governing equations. Aeroacoustic problems typically involve flow-generated noise, with and without the presence of a solid surface, and the propagation of the sound to a receiver far away from the noise source. It is a challenge to obtain accurate numerical solutions to these problems. The NASA Glenn Research Center has been at the forefront in developing and promoting the development of CAA techniques and methodologies for computing the noise generated by aircraft propulsion systems. To assess the technological advancement of CAA, Glenn, in cooperation with the Ohio Aerospace Institute and the AeroAcoustics Research Consortium, organized and hosted the Fourth CAA Workshop on Benchmark Problems. Participants from industry and academia from both the United States and abroad joined to present and discuss solutions to benchmark problems. These demonstrated technical progress ranging from the basic challenges to accurate CAA calculations to the solution of CAA problems of increasing complexity and difficulty. The results are documented in the proceedings of the workshop. Problems were solved in five categories. In three of the five categories, exact solutions were available for comparison with CAA results. A fourth category of problems representing sound generation from either a single airfoil or a blade row interacting with a gust (i.e., problems relevant to fan noise) had approximate analytical or completely numerical solutions. The fifth category of problems involved sound generation in a viscous flow. In this case, the CAA results were compared with experimental data.

The Gap That Can't Go Away: The Catch-22 of Reclassification in Monitoring the Progress of English Learners

ERIC Educational Resources Information Center

Saunders, William M.; Marcelletti, David J.

2013-01-01

When English Learners (ELs) demonstrate English language proficiency, they are reclassified as Fluent English Proficient (RFEP). Subsequently they are often left out of the analysis of EL progress because they are, technically, no longer ELs. This article examines the effects of including and excluding RFEPs from the analysis of EL progress. Based…

Bone Conduction Communication: Research Progress and Directions

DTIC Science & Technology

2017-08-16

ARL-TR-8096 ● AUG 2017 US Army Research Laboratory Bone Conduction Communication: Research Progress and Directions by Maranda...this report when it is no longer needed. Do not return it to the originator. ARL-TR-8096 ● AUG 2017 US Army Research Laboratory...Bone Conduction Communication: Research Progress and Directions by Maranda McBride North Carolina Agricultural and Technical State University

25 CFR 30.123 - What is the Bureau's role in assisting Bureau-funded schools to make AYP?

Code of Federal Regulations, 2010 CFR

2010-04-01

... EDUCATION ADEQUATE YEARLY PROGRESS Failure To Make Adequate Yearly Progress § 30.123 What is the Bureau's...-funded schools to assist them in achieving AYP. This includes technical assistance and other forms of...

25 CFR 30.123 - What is the Bureau's role in assisting Bureau-funded schools to make AYP?

Code of Federal Regulations, 2011 CFR

2011-04-01

... EDUCATION ADEQUATE YEARLY PROGRESS Failure To Make Adequate Yearly Progress § 30.123 What is the Bureau's...-funded schools to assist them in achieving AYP. This includes technical assistance and other forms of...

Black River Technical College, Exploring America's Communities. Progress Report.

ERIC Educational Resources Information Center

Black River Vocational-Technical School, Pocahontas, AR.

In 1996, Arkansas's Black River Technical College (BRTC) participated in the American Association of Community Colleges' Exploring America's Communities project, which worked to strengthen the teaching and learning of American history, literature, and culture at U.S. community colleges. The proposed centerpiece of BRTC's program is called the…

40 CFR 40.150 - Evaluation of applications.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... Relevancy, coupled with the results of technical review, will provide the basis for funding recommendations... will be reviewed for technical merit by at least one reviewer within EPA and at least two reviewers.... Recommendations for continuation of funding will be based on progress toward the accomplishment of the goals set...

40 CFR 35.4235 - Are there specific provisions my group's contract(s) must contain?

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Technical Assistance Procuring A Technical Advisor Or Other Contractor with Tag Funds § 35.4235 Are there specific... progress reports; (3) Expenditures; and (4) Commitments indicating their relationship to established costs...

Missouri local technical assistance program at Missouri University of Science and Technology (formerly University of Missouri--Rolla) : annual progress report January-December 2007.

DOT National Transportation Integrated Search

2009-02-01

This annual report is a summary of the activities during 2007 for the Missouri Local Technical Assistance Program (Missouri LTAP), which is located at Missouri University of Science and Technology. The report highlights Missouri LTAPs performance ...

Global Issues in Career and Technical Fields: Internationalizing the Community College Curriculum.

ERIC Educational Resources Information Center

Peck, Shirley S.

1991-01-01

Presents a rationale for incorporating international content in both general education and career/technical fields, providing a status report on progress to date. Describes four modules prepared by Catonsville Community College (Maryland) instructors for inclusion in criminal justice, air transportation, automotive service, and electronics…

Technical and Vocational Education in Cameroon and Critical Avenues for Development

ERIC Educational Resources Information Center

Che, S. Megan

2007-01-01

Technical and vocational education (TVE) can influence development and economic progress for post-colonial societies. Some newly independent sub-Saharan African countries attempted curricular transformation that might produce a skilled workforce through widespread access to versions of TVE. In Cameroon, no such post-colonial curricular revolution…

The future of nursing: monitoring the progress of recommended change in hospitals, nurse-led clinics, and home health and hospice agencies.

PubMed

Pittman, Patricia; Bass, Emily; Hargraves, John; Herrera, Carolina; Thompson, Pamela

2015-02-01

The objective of this study was to assess the implementation of recommendations of the Institute of Medicine (IOM) report, The Future of Nursing: Leading Change, Advancing Health. In 2010, the IOM made a series of recommendations aimed at transforming the role of nurses in healthcare delivery. We conducted a multiyear survey, in 2011 and 2013, with nurse leaders who were members of the American Organization of Nurse Executives, the National Nursing Centers Consortium, or the Visiting Nurses Association of America. When comparing 2013 to 2011, we find progress in instituting the IOM's recommendations in 3 areas: (1) raising the proportion of employed RNs with at least a bachelor's degree; (2) expanding the proportion of healthcare institutions with nurse residency programs; and (3) offering opportunities for continuing nurse education Our findings suggest that healthcare organizations are transforming to support the recommendations of the IOM.

25 CFR 1000.396 - Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for...

Code of Federal Regulations, 2010 CFR

2010-04-01

... requirements to maintain minimum standards for Tribe/Consortium management systems? 1000.396 Section 1000.396... AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT... minimum standards for Tribe/Consortium management systems? Yes, the Tribe/Consortium must maintain...

25 CFR 1000.169 - How does a Tribe/Consortium initiate the information phase?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false How does a Tribe/Consortium initiate the information... of Initial Annual Funding Agreements § 1000.169 How does a Tribe/Consortium initiate the information phase? A Tribe/Consortium initiates the information phase by submitting a letter of interest to the...

25 CFR 1000.169 - How does a Tribe/Consortium initiate the information phase?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium initiate the information... of Initial Annual Funding Agreements § 1000.169 How does a Tribe/Consortium initiate the information phase? A Tribe/Consortium initiates the information phase by submitting a letter of interest to the...

77 FR 8252 - The International Consortium of Energy Managers; Notice of Preliminary Permit Application...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-14

... International Consortium of Energy Managers; Notice of Preliminary Permit Application Accepted for Filing and... Consortium of Energy Managers filed an application, pursuant to section 4(f) of the Federal Power Act (FPA...: Rexford Wait, International Consortium of Energy Managers, 2416 Cades Way, Vista, CA 92083; (760) 599-0086...

Biodegradation of phenanthrene in bioaugmented microcosm by consortium ASP developed from coastal sediment of Alang-Sosiya ship breaking yard.

PubMed

Patel, Vilas; Patel, Janki; Madamwar, Datta

2013-09-15

A phenanthrene-degrading bacterial consortium (ASP) was developed using sediment from the Alang-Sosiya shipbreaking yard at Gujarat, India. 16S rRNA gene-based molecular analyses revealed that the bacterial consortium consisted of six bacterial strains: Bacillus sp. ASP1, Pseudomonas sp. ASP2, Stenotrophomonas maltophilia strain ASP3, Staphylococcus sp. ASP4, Geobacillus sp. ASP5 and Alcaligenes sp. ASP6. The consortium was able to degrade 300 ppm of phenanthrene and 1000 ppm of naphthalene within 120 h and 48 h, respectively. Tween 80 showed a positive effect on phenanthrene degradation. The consortium was able to consume maximum phenanthrene at the rate of 46 mg/h/l and degrade phenanthrene in the presence of other petroleum hydrocarbons. A microcosm study was conducted to test the consortium's bioremediation potential. Phenanthrene degradation increased from 61% to 94% in sediment bioaugmented with the consortium. Simultaneously, bacterial counts and dehydrogenase activities also increased in the bioaugmented sediment. These results suggest that microbial consortium bioaugmentation may be a promising technology for bioremediation. Copyright © 2013 Elsevier Ltd. All rights reserved.

Publications of the Jet Propulsion Laboratory, January through December 1974. [deep space network, Apollo project, information theory, and space exploration

NASA Technical Reports Server (NTRS)

1975-01-01

Formalized technical reporting is described and indexed, which resulted from scientific and engineering work performed, or managed, by the Jet Propulsion Laboratory. The five classes of publications included are technical reports, technical memorandums, articles from the bimonthly Deep Space Network Progress Report, special publications, and articles published in the open literature. The publications are indexed by author, subject, and publication type and number.

Achievements of the DOT-NASA Joint Program on Remote Sensing and Spatial Information Technologies: Application to Multimodal Transportation

NASA Technical Reports Server (NTRS)

2002-01-01

This report presents three-year accomplishments from the national program on Commercial Remote Sensing and Geospatial Technology (CRSGT) application to transportation, administered by the U.S. Department of Transportation (U.S. DOT) in collaboration with the National Aeronautics and Space Administration (NASA). The joint program was authorized under Section 5113 of the Transportation Equity Act for the 21st Century (TEA-21). This is the first national program of its type focusing on transportation applications of emerging commercial remote sensing technologies. U.S. DOT's Research and Special Programs Administration manages the program in coordination with NASA's Earth Science Enterprise's application programs. The program focuses on applications of CRSGT products and systems for providing smarter and more efficient transportation operations and services. The program is performed in partnership with four major National Consortia for Remote Sensing in Transportation (NCRST). Each consortium focuses on research and development of products in one of the four priority areas for transportation application, and includes technical application and demonstration projects carried out in partnership with industries and service providers in their respective areas. The report identifies products and accomplishments from each of the four consortia in meeting the goal of providing smarter and more efficient transportation services. The products and results emerging from the program are being implemented in transportation operations and services through state and local agencies. The Environmental Assessment and Application Consortium (NCRST-E) provides leadership for developing and deploying cost effective environmental and transportation planning services, and integrates CRSGT advances for achieving smarter and cost effective corridor planning. The Infrastructure Management Consortium (NCRST-I) provides leadership in technologies that achieve smarter and cheaper ways of managing transportation infrastructure assets, operation, and inspection, and integrates CRSGT advances for achieving infrastructure security. The Traffic Flow Consortium (NCRST-F) provides leadership to develop new tools for regional traffic flow management including heavy vehicles and intermodal flow of freight, and integrates CRSGT advances for complementing and extending the reach of ITS user services. The Safety, Hazards and Disasters (NCRST-H) provides leadership for deploying remote sensing technology to locate transportation hazards and improve disaster recovery, and integrates CRSGT advances for application to protect transportation systems from terrorism. The DOT-NASA team is proud to present this report of accomplishments on products and results emerging from the joint program for application to transportation practice.

Hawaii Space Grant Consortium

NASA Technical Reports Server (NTRS)

Flynn, Luke P.

2005-01-01

The Hawai'i Space Grant Consortium is composed of ten institutions of higher learning including the University of Hawai'i at Manoa, the University of Hawai'i at Hilo, the University of Guam, and seven Community Colleges spread over the 4 main Hawaiian islands. Geographic separation is not the only obstacle that we face as a Consortium. Hawai'i has been mired in an economic downturn due to a lack of tourism for almost all of the period (2001 - 2004) covered by this report, although hotel occupancy rates and real estate sales have sky-rocketed in the last year. Our challenges have been many including providing quality educational opportunities in the face of shrinking State and Federal budgets, encouraging science and technology course instruction at the K-12 level in a public school system that is becoming less focused on high technology and more focused on developing basic reading and math skills, and assembling community college programs with instructors who are expected to teach more classes for the same salary. Motivated people can overcome these problems. Fortunately, the Hawai'i Space Grant Consortium (HSGC) consists of a group of highly motivated and talented individuals who have not only overcome these obstacles, but have excelled with the Program. We fill a critical need within the State of Hawai'i to provide our children with opportunities to pursue their dreams of becoming the next generation of NASA astronauts, engineers, and explorers. Our strength lies not only in our diligent and creative HSGC advisory board, but also with Hawai'i's teachers, students, parents, and industry executives who are willing to invest their time, effort, and resources into Hawai'i's future. Our operational philosophy is to FACE the Future, meaning that we will facilitate, administer, catalyze, and educate in order to achieve our objective of creating a highly technically capable workforce both here in Hawai'i and for NASA. In addition to administering to programs and educating the public in the traditional sense, we also work to facilitate partnerships between other departments (geology & geophysics, engineering, geography, astronomy), state and federal government agencies in Hawai'i, and private industry. In some cases, we are the catalyst for new partnerships between private agency sponsors and education projects or for new joint research and education projects between industry and the University faculty.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Downing, M.

America's desire for energy independence places a new demand on alternative fuel production. Additional interest and emphasis are being placed on alternatives such as solar, wind, biofuels and nuclear energy. The nuclear fuel production option brings a new look at risk and residual waste management for a number of communities that have traditionally remained outside the energy debate. With the Federal requirements for environmental justice and public participation in energy and environmental decision-making, proponents of alternative energy production facilities will find themselves participating in discussions of risk, production, storage and disposal of hazardous materials and waste matters with low incomemore » and minority members in communities where these facilities are located or wish to locate. The fundamental principal of environmental justice is that all residents should have meaningful and intelligent participation in all aspects of environmental decision-making that could affect their community. Impacted communities must have the resources and ability to effectively marshall data and other information in order to make informed and intelligent decisions. Traditionally, many low-income and minority communities have lacked access to the required information, decision-makers and technical advisers to make informed decisions with respect to various risks that accompany alternative energy production, hazardous materials storage and nuclear waste management. In order to provide the necessary assistance to these communities, the Departments of Energy and Agriculture have teamed with others to cerate the Alternative Energy Consortium. The Alternative Energy Consortium is a collaboration of non-profit organizations, Federal agencies, Historically Black Colleges and Universities and Minority Serving Institutions (HBCU/MSIs), and private sector corporations (energy industry specialists) designed to explore and develop opportunities that empower minorities to own and work in all aspects of the field of alternative energy. The Consortium's primary objectives are to find ways to: - Include minorities in the development and ownership of infrastructure in the alternative energy industry; - Promote research and education programs to inform the public about risks and benefits of various forms of alternative energy; - Build a Mentor/Protege Program between HBCU/MSIs and industry leaders to enhance minority participation in ownership and career success in alternative energy production and distribution. The Consortium will work together to create a process whereby minorities and low income individuals will be recruited, educated, and mentored to maximize alternative energy ownership and job opportunities. Industry specialists and government representatives will work with academicians and others to: 1. research areas and methods where minorities and rural communities can engage in the industry; 2. invest in minorities by serving as mentors to minority serving institutions by offering hands-on experience through apprenticeships; 3. work to identify ownership opportunities for minorities; and 4. work to develop legislation that supports economic development and participation for minorities and rural communities in the industry. To accomplish this goal, the Consortium has set out a three-phase plan. Phase I organized a meeting of professionals to discuss the concept, explore the fundamentals, identify key players, and draft next steps. The group took a critical look at the energy industry: 1) trends, 2) economics, 3) limited number of minorities; and 4) infrastructure. Through that process the group identified four areas that would greatly impact economic development for minorities and rural communities: I Energy; II Broadband Communications; III Education; IV Labor Resources. Phase II presented a roundtable panel discussion that continued to refine the Consortium. The goal of these discussions is to produce a well-balanced Consortium committed to working together to produce effective solutions that bridge the gap between alternative energy and minorities and rural communities. Phase III is the implementation stage that will put the consortium plans into action. This will include the Mentor/Protege Program between HBCU/MSIs and industry leaders, and any additional actions that come from the Phase II roundtable discussion. Phase III will also include a panel discussion at the State of Environmental Justice in America 2008 Conference in Washington, DC in March, 2008. The Consortium's work should facilitate the siting and management of alternative energy production facilities in communities that include a significant number of minority and/or low income individuals. This effort should increase America's prospects for energy independence. (authors)« less

The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model.

PubMed

Bateman, Randall J; Benzinger, Tammie L; Berry, Scott; Clifford, David B; Duggan, Cynthia; Fagan, Anne M; Fanning, Kathleen; Farlow, Martin R; Hassenstab, Jason; McDade, Eric M; Mills, Susan; Paumier, Katrina; Quintana, Melanie; Salloway, Stephen P; Santacruz, Anna; Schneider, Lon S; Wang, Guoqiao; Xiong, Chengjie

2017-01-01

The Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) trial is an adaptive platform trial testing multiple drugs to slow or prevent the progression of Alzheimer's disease in autosomal dominant Alzheimer's disease (ADAD) families. With completion of enrollment of the first two drug arms, the DIAN-TU now plans to add new drugs to the platform, designated as the Next Generation (NexGen) prevention trial. In collaboration with ADAD families, philanthropic organizations, academic leaders, the DIAN-TU Pharma Consortium, the National Institutes of Health, and regulatory colleagues, the DIAN-TU developed innovative clinical study designs for the DIAN-TU NexGen prevention trial. Our expanded trial toolbox consists of a disease progression model for ADAD, primary end point DIAN-TU cognitive performance composite, biomarker development, self-administered cognitive assessments, adaptive dose adjustments, and blinded data collection through the last participant completion. These steps represent elements to improve efficacy of the adaptive platform trial and a continued effort to optimize prevention and treatment trials in ADAD. Copyright © 2016 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

Psychiatric Genomics: An Update and an Agenda.

PubMed

Sullivan, Patrick F; Agrawal, Arpana; Bulik, Cynthia M; Andreassen, Ole A; Børglum, Anders D; Breen, Gerome; Cichon, Sven; Edenberg, Howard J; Faraone, Stephen V; Gelernter, Joel; Mathews, Carol A; Nievergelt, Caroline M; Smoller, Jordan W; O'Donovan, Michael C

2018-01-01

The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of psychiatry. This global effort is dedicated to rapid progress and open science, and in the past decade it has delivered an increasing flow of new knowledge about the fundamental basis of common psychiatric disorders. The PGC has recently commenced a program of research designed to deliver "actionable" findings-genomic results that 1) reveal fundamental biology, 2) inform clinical practice, and 3) deliver new therapeutic targets. The central idea of the PGC is to convert the family history risk factor into biologically, clinically, and therapeutically meaningful insights. The emerging findings suggest that we are entering a phase of accelerated genetic discovery for multiple psychiatric disorders. These findings are likely to elucidate the genetic portions of these truly complex traits, and this knowledge can then be mined for its relevance for improved therapeutics and its impact on psychiatric practice within a precision medicine framework. [AJP at 175: Remembering Our Past As We Envision Our Future November 1946: The Genetic Theory of Schizophrenia Franz Kallmann's influential twin study of schizophrenia in 691 twin pairs was the largest in the field for nearly four decades. (Am J Psychiatry 1946; 103:309-322 )].

History of thyroid disease and survival of ovarian cancer patients: results from the Ovarian Cancer Association Consortium, a brief report.

PubMed

Minlikeeva, Albina N; Freudenheim, Jo L; Cannioto, Rikki A; Eng, Kevin H; Szender, J Brian; Mayor, Paul; Etter, John L; Cramer, Daniel W; Diergaarde, Brenda; Doherty, Jennifer A; Dörk, Thilo; Edwards, Robert; deFazio, Anna; Friel, Grace; Goodman, Marc T; Hillemanns, Peter; Høgdall, Estrid; Jensen, Allan; Jordan, Susan J; Karlan, Beth Y; Kjær, Susanne K; Klapdor, Rüdiger; Matsuo, Keitaro; Mizuno, Mika; Nagle, Christina M; Odunsi, Kunle; Paddock, Lisa; Rossing, Mary Anne; Schildkraut, Joellen M; Schmalfeldt, Barbara; Segal, Brahm H; Starbuck, Kristen; Terry, Kathryn L; Webb, Penelope M; Zsiros, Emese; Ness, Roberta B; Modugno, Francesmary; Bandera, Elisa V; Chang-Claude, Jenny; Moysich, Kirsten B

2017-09-26

Findings from in vitro studies suggest that increased exposure to thyroid hormones can influence progression of ovarian tumours. However, epidemiologic evidence on this topic is limited. We pooled data from 11 studies from the Ovarian Cancer Association Consortium. Using multivariate Cox proportional hazards models, we estimated associations between hyper- and hypothyroidism and medications prescribed for these conditions with 5-year all-cause survival among women diagnosed with invasive ovarian cancer. Overall, there was a nonsignificant association with history of hyperthyroidism (n=160 cases) and mortality (HR=1.22; 95% CI=0.97-1.53). Furthermore, diagnosis of hyperthyroidism within the 5 years before ovarian cancer diagnosis was associated with an increased risk of death (HR=1.94; 95% CI=1.19-3.18). A more modest association was observed with history of hypothyroidism (n=624 cases) and mortality (HR=1.16; 95% CI=1.03-1.31). Neither duration of hypothyroidism nor use of thyroid medications was associated with survival. In this large study of women with ovarian cancer, we found that recent history of hyperthyroidism and overall history of hypothyroidism were associated with worse 5-year survival.

Technical adequacy of growth estimates from a computer adaptive test: Implications for progress monitoring.

PubMed

Van Norman, Ethan R; Nelson, Peter M; Parker, David C

2017-09-01

Computer adaptive tests (CATs) hold promise to monitor student progress within multitiered systems of support. However, the relationship between how long and how often data are collected and the technical adequacy of growth estimates from CATs has not been explored. Given CAT administration times, it is important to identify optimal data collection schedules to minimize missed instructional time. We used simulation methodology to investigate how the duration and frequency of data collection influenced the reliability, validity, and precision of growth estimates from a math CAT. A progress monitoring dataset of 746 Grade 4, 664 Grade 5, and 400 Grade 6 students from 40 schools in the upper Midwest was used to generate model parameters. Across grades, 53% of students were female and 53% were White. Grade level was not as influential as the duration and frequency of data collection on the technical adequacy of growth estimates. Low-stakes decisions were possible after 14-18 weeks when data were collected weekly (420-540 min of assessment), 20-24 weeks when collected every other week (300-360 min of assessment), and 20-28 weeks (150-210 min of assessment) when data were collected once a month, depending on student grade level. The validity and precision of growth estimates improved when the duration and frequency of progress monitoring increased. Given the amount of time required to obtain technically adequate growth estimates in the present study, results highlight the importance of weighing the potential costs of missed instructional time relative to other types of assessments, such as curriculum-based measures. Implications for practice, research, as well as future directions are also discussed. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

24 CFR 1006.430 - Corrective and remedial action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... plan; (3) Made substantial progress in carrying out its program and achieving its quantifiable goals as... to submit progress schedules for completing activities or complying with the requirements of the Act... appropriate technical assistance using existing grant funds or other available resources to overcome the...

Computational Tools and Facilities for the Next-Generation Analysis and Design Environment

NASA Technical Reports Server (NTRS)

Noor, Ahmed K. (Compiler); Malone, John B. (Compiler)

1997-01-01

This document contains presentations from the joint UVA/NASA Workshop on Computational Tools and Facilities for the Next-Generation Analysis and Design Environment held at the Virginia Consortium of Engineering and Science Universities in Hampton, Virginia on September 17-18, 1996. The presentations focused on the computational tools and facilities for analysis and design of engineering systems, including, real-time simulations, immersive systems, collaborative engineering environment, Web-based tools and interactive media for technical training. Workshop attendees represented NASA, commercial software developers, the aerospace industry, government labs, and academia. The workshop objectives were to assess the level of maturity of a number of computational tools and facilities and their potential for application to the next-generation integrated design environment.

25 CFR 1000.425 - How does a Tribe/Consortium request an informal conference?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false How does a Tribe/Consortium request an informal... INDIAN SELF-DETERMINATION AND EDUCATION ACT Appeals § 1000.425 How does a Tribe/Consortium request an informal conference? The Tribe/Consortium shall file its request for an informal conference with the office...

25 CFR 1000.396 - Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for Tribe/Consortium management systems? 1000.396 Section 1000.396... Miscellaneous Provisions § 1000.396 Does a Tribe/Consortium have additional ongoing requirements to maintain...

25 CFR 1000.222 - How does a Tribe/Consortium obtain a waiver?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium obtain a waiver? 1000.222...-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.222 How does a Tribe/Consortium obtain a waiver? To obtain a waiver, the Tribe/Consortium must: (a) Submit a written request from the designated Tribal...

25 CFR 1000.333 - How does a Tribe/Consortium retrocede a program?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium retrocede a program? 1000.333...-DETERMINATION AND EDUCATION ACT Retrocession § 1000.333 How does a Tribe/Consortium retrocede a program? The Tribe/Consortium must submit: (a) A written notice to: (1) The Office of Self-Governance for BIA...

25 CFR 1000.425 - How does a Tribe/Consortium request an informal conference?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false How does a Tribe/Consortium request an informal... INDIAN SELF-DETERMINATION AND EDUCATION ACT Appeals § 1000.425 How does a Tribe/Consortium request an informal conference? The Tribe/Consortium shall file its request for an informal conference with the office...

25 CFR 1000.400 - Can a Tribe/Consortium retain savings from programs?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Can a Tribe/Consortium retain savings from programs? 1000...-DETERMINATION AND EDUCATION ACT Miscellaneous Provisions § 1000.400 Can a Tribe/Consortium retain savings from programs? Yes, for BIA programs, the Tribe/Consortium may retain savings for each fiscal year during which...

25 CFR 1000.315 - When must the Tribe/Consortium return funds to the Department?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false When must the Tribe/Consortium return funds to the... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reassumption § 1000.315 When must the Tribe/Consortium return funds to the Department? The Tribe/Consortium must repay funds to the Department as soon as practical...

25 CFR 1000.333 - How does a Tribe/Consortium retrocede a program?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false How does a Tribe/Consortium retrocede a program? 1000.333...-DETERMINATION AND EDUCATION ACT Retrocession § 1000.333 How does a Tribe/Consortium retrocede a program? The Tribe/Consortium must submit: (a) A written notice to: (1) The Office of Self-Governance for BIA...

25 CFR 1000.315 - When must the Tribe/Consortium return funds to the Department?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false When must the Tribe/Consortium return funds to the... INDIAN SELF-DETERMINATION AND EDUCATION ACT Reassumption § 1000.315 When must the Tribe/Consortium return funds to the Department? The Tribe/Consortium must repay funds to the Department as soon as practical...

Metro-Minnesota Community Clinical Oncology Program (MM-CCOP) | Division of Cancer Prevention

Cancer.gov

The Metro-Minnesota Community Clinical Oncology (MMCCOP) program has a long-standing history which clearly demonstrates the success of the consortium, as demonstrated by both the ongoing commitment of the original consortium members and the growth of the consortium from 1979 through 2014. The MMCCOP consortium represents an established community program base which began in

Progress and Prospect: A Report Submitted to the Governing Board of the Maricopa County Community College District.

ERIC Educational Resources Information Center

Maricopa Technical Community Coll., Phoenix, AZ.

This two-part report seeks to outline the progress made to date by Maricopa Technical Community College (MTCC) through its first eight years of operation, and to recommend specific actions which might be taken in the future by the college to insure its continued progress and response to community needs in light of constraints on funding and…

Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium.

PubMed

Stevens, Wendy B C; Mendeville, Matias; Redd, Robert; Clear, Andrew J; Bladergroen, Reno; Calaminici, Maria; Rosenwald, Andreas; Hoster, Eva; Hiddemann, Wolfgang; Gaulard, Philippe; Xerri, Luc; Salles, Gilles; Klapper, Wolfram; Pfreundschuh, Michael; Jack, Andrew; Gascoyne, Randy D; Natkunam, Yasodha; Advani, Ranjana; Kimby, Eva; Sander, Birgitta; Sehn, Laurie H; Hagenbeek, Anton; Raemaekers, John; Gribben, John; Kersten, Marie José; Ylstra, Bauke; Weller, Edie; de Jong, Daphne

2017-08-01

In follicular lymphoma, studies addressing the prognostic value of microenvironment-related immunohistochemical markers and tumor cell-related genetic markers have yielded conflicting results, precluding implementation in practice. Therefore, the Lunenburg Lymphoma Biomarker Consortium performed a validation study evaluating published markers. To maximize sensitivity, an end of spectrum design was applied for 122 uniformly immunochemotherapy-treated follicular lymphoma patients retrieved from international trials and registries. The criteria were: early failure, progression or lymphoma-related death <2 years versus long remission, response duration of >5 years. Immunohistochemical staining for T cells and macrophages was performed on tissue microarrays from initial biopsies and scored with a validated computer-assisted protocol. Shallow whole-genome and deep targeted sequencing was performed on the same samples. The 96/122 cases with complete molecular and immunohistochemical data were included in the analysis. EZH2 wild-type ( P =0.006), gain of chromosome 18 ( P =0.002), low percentages of CD8+ cells ( P =0.011) and CD163+ areas ( P =0.038) were associated with early failure. No significant differences in other markers were observed, thereby refuting previous claims of their prognostic significance. Using an optimized study design, this Lunenburg Lymphoma Biomarker Consortium study substantiates wild-type EZH2 status, gain of chromosome 18, low percentages of CD8+ cells and CD163+ area as predictors of early failure to immunochemotherapy in follicular lymphoma treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP [-like]), while refuting the prognostic impact of various other markers. Copyright© 2017 Ferrata Storti Foundation.

"Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015.

PubMed

Fernando, Ruani N; Chaudhari, Umesh; Escher, Sylvia E; Hengstler, Jan G; Hescheler, Jürgen; Jennings, Paul; Keun, Hector C; Kleinjans, Jos C S; Kolde, Raivo; Kollipara, Laxmikanth; Kopp-Schneider, Annette; Limonciel, Alice; Nemade, Harshal; Nguemo, Filomain; Peterson, Hedi; Prieto, Pilar; Rodrigues, Robim M; Sachinidis, Agapios; Schäfer, Christoph; Sickmann, Albert; Spitkovsky, Dimitry; Stöber, Regina; van Breda, Simone G J; van de Water, Bob; Vivier, Manon; Zahedi, René P; Vinken, Mathieu; Rogiers, Vera

2016-06-01

SEURAT-1 is a joint research initiative between the European Commission and Cosmetics Europe aiming to develop in vitro- and in silico-based methods to replace the in vivo repeated dose systemic toxicity test used for the assessment of human safety. As one of the building blocks of SEURAT-1, the DETECTIVE project focused on a key element on which in vitro toxicity testing relies: the development of robust and reliable, sensitive and specific in vitro biomarkers and surrogate endpoints that can be used for safety assessments of chronically acting toxicants, relevant for humans. The work conducted by the DETECTIVE consortium partners has established a screening pipeline of functional and "-omics" technologies, including high-content and high-throughput screening platforms, to develop and investigate human biomarkers for repeated dose toxicity in cellular in vitro models. Identification and statistical selection of highly predictive biomarkers in a pathway- and evidence-based approach constitute a major step in an integrated approach towards the replacement of animal testing in human safety assessment. To discuss the final outcomes and achievements of the consortium, a meeting was organized in Brussels. This meeting brought together data-producing and supporting consortium partners. The presentations focused on the current state of ongoing and concluding projects and the strategies employed to identify new relevant biomarkers of toxicity. The outcomes and deliverables, including the dissemination of results in data-rich "-omics" databases, were discussed as were the future perspectives of the work completed under the DETECTIVE project. Although some projects were still in progress and required continued data analysis, this report summarizes the presentations, discussions and the outcomes of the project.

“Watching the Detectives” Report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November, 2015

PubMed Central

Fernando, Ruani N.; Chaudhari, Umesh; Escher, Sylvia E.; Hengstler, Jan G.; Hescheler, Jürgen; Jennings, Paul; Keun, Hector C.; Kleinjans, Jos C. S.; Kolde, Raivo; Kollipara, Laxmikanth; Kopp-Schneider, Annette; Limonciel, Alice; Nemade, Harshal; Nguemo, Filomain; Peterson, Hedi; Prieto, Pilar; Rodrigues, Robim M.; Sachinidis, Agapios; Schäfer, Christoph; Sickmann, Albert; Spitkovsky, Dimitry; Stöber, Regina; van Breda, Simone G.J.; van de Water, Bob; Vivier, Manon; Zahedi, René P.

2017-01-01

SEURAT-1 is a joint research initiative between the European Commission and Cosmetics Europe aiming to develop in vitro and in silico based methods to replace the in vivo repeated dose systemic toxicity test used for the assessment of human safety. As one of the building blocks of SEURAT-1, the DETECTIVE project focused on a key element on which in vitro toxicity testing relies: the development of robust and reliable, sensitive and specific in vitro biomarkers and surrogate endpoints that can be used for safety assessments of chronically acting toxicants, relevant for humans. The work conducted by the DETECTIVE consortium partners has established a screening pipeline of functional and “-omics” technologies, including high-content and high-throughput screening platforms, to develop and investigate human biomarkers for repeated dose toxicity in cellular in vitro models. Identification and statistical selection of highly predictive biomarkers in a pathway- and evidence-based approach constitutes a major step in an integrated approach towards the replacement of animal testing in human safety assessment. To discuss the final outcomes and achievements of the consortium, a meeting was organized in Brussels. This meeting brought together data-producing and supporting consortium partners. The presentations focused on the current state of ongoing and concluding projects and the strategies employed to identify new relevant biomarkers of toxicity. The outcomes and deliverables, including the dissemination of results in data-rich “-omics” databases, were discussed as were the future perspectives of the work completed under the DETECTIVE project. Although some projects were still in progress and required continued data analysis, this report summarizes the presentations, discussions and the outcomes of the project. PMID:27129694

Soil mesocosm studies on atrazine bioremediation.

PubMed

Sagarkar, Sneha; Nousiainen, Aura; Shaligram, Shraddha; Björklöf, Katarina; Lindström, Kristina; Jørgensen, Kirsten S; Kapley, Atya

2014-06-15

Accumulation of pesticides in the environment causes serious issues of contamination and toxicity. Bioremediation is an ecologically sound method to manage soil pollution, but the bottleneck here, is the successful scale-up of lab-scale experiments to field applications. This study demonstrates pilot-scale bioremediation in tropical soil using atrazine as model pollutant. Mimicking field conditions, three different bioremediation strategies for atrazine degradation were explored. 100 kg soil mesocosms were set-up, with or without atrazine application history. Natural attenuation and enhanced bioremediation were tested, where augmentation with an atrazine degrading consortium demonstrated best pollutant removal. 90% atrazine degradation was observed in six days in soil previously exposed to atrazine, while soil without history of atrazine use, needed 15 days to remove the same amount of amended atrazine. The bacterial consortium comprised of 3 novel bacterial strains with different genetic atrazine degrading potential. The progress of bioremediation was monitored by measuring the levels of atrazine and its intermediate, cyanuric acid. Genes from the atrazine degradation pathway, namely, atzA, atzB, atzD, trzN and trzD were quantified in all mesocosms for 60 days. The highest abundance of all target genes was observed on the 6th day of treatment. trzD was observed in the bioaugmented mesocosms only. The bacterial community profile in all mesocosms was monitored by LH-PCR over a period of two months. Results indicate that the communities changed rapidly after inoculation, but there was no drastic change in microbial community profile after 1 month. Results indicated that efficient bioremediation of atrazine using a microbial consortium could be successfully up-scaled to pilot scale. Copyright © 2014 Elsevier Ltd. All rights reserved.

International Lymphoma Epidemiology Consortium

Cancer.gov

The InterLymph Consortium, or formally the International Consortium of Investigators Working on Non-Hodgkin's Lymphoma Epidemiologic Studies, is an open scientific forum for epidemiologic research in non-Hodgkin's lymphoma.

Optical fiber sensors for materials and structures characterization

NASA Technical Reports Server (NTRS)

Lindner, D. K.; Claus, R. O.

1991-01-01

The final technical report on Optical Fiber Sensors for Materials and Structures Characterization, covering the period August 1990 through August 1991 is presented. Research programs in the following technical areas are described; sapphire optical fiber sensors; vibration analysis using two-mode elliptical core fibers and sensors; extrinsic Fabry-Perot interferometer development; and coatings for fluorescent-based sensor. Research progress in each of these areas was substantial, as evidenced by the technical publications which are included as appendices.

Battery Test Manual For Electric Vehicles, Revision 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christophersen, Jon P.

2015-06-01

This battery test procedure manual was prepared for the United States Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), Vehicle Technologies Office. It is based on technical targets for commercial viability established for energy storage development projects aimed at meeting system level DOE goals for Electric Vehicles (EV). The specific procedures defined in this manual support the performance and life characterization of advanced battery devices under development for EVs. However, it does share some methods described in the previously published battery test manual for plug-in hybrid electric vehicles. Due to the complexity of some of themore » procedures and supporting analysis, future revisions including some modifications and clarifications of these procedures are expected. As in previous battery and capacitor test manuals, this version of the manual defines testing methods for full-size battery systems, along with provisions for scaling these tests for modules, cells or other subscale level devices. The DOE-United States Advanced Battery Consortium (USABC), Technical Advisory Committee (TAC) supported the development of the manual. Technical Team points of contact responsible for its development and revision are Chul Bae of Ford Motor Company and Jon P. Christophersen of the Idaho National Laboratory. The development of this manual was funded by the Unites States Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Office. Technical direction from DOE was provided by David Howell, Energy Storage R&D Manager and Hybrid Electric Systems Team Leader. Comments and questions regarding the manual should be directed to Jon P. Christophersen at the Idaho National Laboratory (jon.christophersen@inl.gov).« less

Tribal Colleges and Universities/American Indian Research and Education Initiatives Advanced Manufacturing Technical Assistance Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Atcitty, Stanley

The overall goal of this project is to establish a network of TCUs with essential advanced manufacturing (AM) facilities, associated training and education programs, and private sector and federal agency partnerships to both prepare an American Indian AM workforce and create economic and employment opportunities within Tribal communities through design, manufacturing, and marketing of high quality products. Some examples of high quality products involve next generation grid components such as mechanical energy storage, cabling for distribution of energy, and electrochemical energy storage enclosures. Sandia National Laboratories (Sandia) is tasked to provide technical advising, planning, and academic program development support formore » the TCU/American Indian Higher Education Consortium (AIHEC) Advanced Manufacturing Project. The TCUs include Bay Mills Community College (BMCC), Cankdeska Cikana Community College (CCCC), Navajo Technical University (NTU), Southwestern Indian Polytechnic Institute (SIPI), and Salish Kooteani College. AIHEC and Sandia, with collaboration from SIPI, will be establishing an 8-week summer institute on the SIPI campus during the summer of 2017. Up to 20 students from TCUs are anticipated to take part in the summer program. The goal of the program is to bring AM science, technology, engineering, and mathematics (STEM) awareness and opportunities for the American Indian students. Prior to the summer institute, Sandia will be providing reviews on curriculum plans at the each of the TCUs to ensure the content is consistent with current AM design and engineering practice. In addition, Sandia will provide technical assistance to each of the TCUs in regards to their current AM activities.« less

44 CFR 206.437 - State administrative plan.

Code of Federal Regulations, 2010 CFR

2010-10-01

... requests for advances of funds and reimbursement; (vii) Monitor and evaluate the progress and completion of... technical assistance as required to subgrantee(s); (xi) Comply with the administrative and audit requirements of 44 CFR parts 13 and 206; (xii) Provide quarterly progress reports to the Regional Administrator...

25 CFR 30.122 - Must the Bureau assist a school it identified for school improvement, corrective action, or...

Code of Federal Regulations, 2010 CFR

2010-04-01

..., DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Failure To Make Adequate Yearly Progress § 30... restructuring, the Bureau must provide technical or other assistance described in 20 U.S.C. 6316(b)(4) and 20 U...

44 CFR 206.437 - State administrative plan.

Code of Federal Regulations, 2011 CFR

2011-10-01

... requests for advances of funds and reimbursement; (vii) Monitor and evaluate the progress and completion of... technical assistance as required to subgrantee(s); (xi) Comply with the administrative and audit requirements of 44 CFR parts 13 and 206; (xii) Provide quarterly progress reports to the Regional Administrator...

25 CFR 30.122 - Must the Bureau assist a school it identified for school improvement, corrective action, or...

Code of Federal Regulations, 2011 CFR

2011-04-01

..., DEPARTMENT OF THE INTERIOR EDUCATION ADEQUATE YEARLY PROGRESS Failure To Make Adequate Yearly Progress § 30... restructuring, the Bureau must provide technical or other assistance described in 20 U.S.C. 6316(b)(4) and 20 U...

Assessment Program Technical Progress Report, 1997-1998.

ERIC Educational Resources Information Center

Eickmeyer, Barbara; Hill, Stephen

This Assessment Program Progress Report (APPR) records the institutional activities that have taken place at Coconino Community College (CCC) during the 1997-98 academic year. It presents models, timelines, accomplishments, and opportunities for improvement in the assessment practices at CCC. Implementation and outcomes information is included for…

Diagnostic Efficiency of easyCBM[R] Math: Oregon. Technical Report #1009

ERIC Educational Resources Information Center

Anderson, Daniel; Alonzo, Julie; Tindal, Gerald

2010-01-01

The easyCBM[R] assessment system is an online benchmark and progress monitoring assessment system designed for use within a response to intervention framework. Educators using easyCBM[R] are often interested in using the results to predict students' state test performance. In the following technical document, we report diagnostic efficiency…

Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort: Wave 2 (2010)-- Questionnaire. Technical Report 71A

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2012

2012-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the questionnaire for the LSAY 2009 cohort Wave 2 (2010) data set.

Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort: Wave 3 (2011)--Questionnaire. Technical Report 72A

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2012

2012-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the questionnaire for the LSAY 2009 cohort Wave 3 (2011) data set.

Educational Reform and the World of Work: Italy

ERIC Educational Resources Information Center

von Blumenthal, Viktor

1977-01-01

One of a four-issue series on educational reform and the world of work in Europe, this issue discusses educational planning and secondary school reform in Italy. Topics discussed include planning and research in vocational-technical education, and the relation between acquisition of specific skills and scientific and technical progress. (Author/DB)

Longitudinal Surveys of Australian Youth (LSAY) 2009 Cohort: Wave 2 (2010)--Frequency Tables. Technical Report 71B

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2012

2012-01-01

The Longitudinal Surveys of Australian Youth (LSAY) program studies the progress of several groups of young Australians as they move from school into post-secondary education and work. This technical paper contains the frequency tables for the LSAY 2009 cohort Wave 2 (2010) data set.

Higher Education in Kazakhstan and the Bologna Process

ERIC Educational Resources Information Center

Piven, G.; Pak, I.U.

2006-01-01

The constantly rising role of higher education in the twenty-first century goes hand in hand with scientific and technical progress and the global technologization of the developed countries of the world. A country's level of technical and technological development determines its economic condition, its national security, and its role in the world…

A State Response to Indian Vocational Education.

ERIC Educational Resources Information Center

McConnell, Bruce

In 1977 more than 500 Native Americans attended Wisconsin's vocational, technical and adult schools located in the state's 16 vocational-technical districts. While many problems still lack a clear identification and many new programs are needed to meet the needs of Native Americans, a great deal of progress has been made. A group of four Indians…

Analytical Chemistry Division. Annual progress report for period ending December 31, 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyon, W.S.

1981-05-01

This report is divided into: analytical methodology; mass and emission spectrometry; technical support; bio/organic analysis; nuclear and radiochemical analysis; quality assurance, safety, and tabulation of analyses; supplementary activities; and presentation of research results. Separate abstracts were prepared for the technical support, bio/organic analysis, and nuclear and radiochemical analysis. (DLC)

Scientific and Technical Information Transfer for Education (STITE). Research Report No. 2.

ERIC Educational Resources Information Center

Zunde, Pranas

STITE (Scientific and Technical Information Transfer for Education) is basically a system to interface between science information and the science learner. As such STITE acts as a link between STIC (Science and Technology Infromation Centers) and LIS (Learning Information Systems). In this second progress report the internal knowledge of STITE is…

Mathematics Technical Report: Exercise Volume. National Assessment of Educational Progress. Report No. 04-MA-20.

ERIC Educational Resources Information Center

Education Commission of the States, Denver, CO. National Assessment of Educational Progress.

Included in Chapter 1 of this report are background information on the 1972-73 mathematics assessment; details of the computational formulas used in reporting results; and explanations of the technical documentation, exercise presentation, documentation pages, scoring guides, and data tables for released and unreleased exercises. The remainder of…

Experimentation with Computer-Assisted Instruction in Technical Education. Semi-Annual Progress Report.

ERIC Educational Resources Information Center

Mitzel, Harold E.; Brandon, George L.

A series of five reports is presented which describes the activities carried out by the Pennsylvania State University group engaged in research in computer-assisted instruction (CAI) in vocational-technical education. The reports cover the period January 1968-June 1968 and deal with: 1) prior knowledge and individualized instruction; 2) numerical…

Do failures in non-technical skills contribute to fatal medical accidents in Japan? A review of the 2010–2013 national accident reports

PubMed Central

Uramatsu, Masashi; Fujisawa, Yoshikazu; Mizuno, Shinya; Souma, Takahiro; Komatsubara, Akinori; Miki, Tamotsu

2017-01-01

Objectives We sought to clarify how large a proportion of fatal medical accidents can be considered to be caused by poor non-technical skills, and to support development of a policy to reduce number of such accidents by making recommendations about possible training requirements. Design Summaries of reports of fatal medical accidents, published by the Japan Medical Safety Research Organization, were reviewed individually. Three experienced clinicians and one patient safety expert conducted the reviews to determine the cause of death. Views of the patient safety expert were given additional weight in the overall determination. Setting A total of 73 summary reports of fatal medical accidents were reviewed. These reports had been submitted by healthcare organisations across Japan to the Japan Medical Safety Research Organization between April 2010 and March 2013. Primary and secondary outcome measures The cause of death in fatal medical accidents, categorised into technical skills, non-technical skills and inevitable progress of disease were evaluated. Non-technical skills were further subdivided into situation awareness, decision making, communication, team working, leadership, managing stress and coping with fatigue. Results Overall, the cause of death was identified as non-technical skills in 34 cases (46.6%), disease progression in 33 cases (45.2%) and technical skills in two cases (5.5%). In two cases, no consensual determination could be achieved. Further categorisation of cases of non-technical skills were identified as 14 cases (41.2%) of problems with situation awareness, eight (23.5%) with team working and three (8.8%) with decision making. These three subcategories, or combinations of them, were identified as the cause of death in 33 cases (97.1%). Conclusions Poor non-technical skills were considered to be a significant cause of adverse events in nearly half of the fatal medical accidents examined. Improving non-technical skills may be effective for reducing accidents, and training in particular subcategories of non-technical skills may be especially relevant. PMID:28209605

Establishment of a Multi-State Experiential Pharmacy Program Consortium

PubMed Central

Unterwagner, Whitney L.; Byrd, Debbie C.

2008-01-01

In 2002, a regional consortium was created for schools and colleges of pharmacy in Georgia and Alabama to assist experiential education faculty and staff members in streamlining administrative processes, providing required preceptor development, establishing a professional network, and conducting scholarly endeavors. Five schools and colleges of pharmacy with many shared experiential practice sites formed a consortium to help experiential faculty and staff members identify, discuss, and solve common experience program issues and challenges. During its 5 years in existence, the Southeastern Pharmacy Experiential Education Consortium has coordinated experiential schedules, developed and implemented uniform evaluation tools, coordinated site and preceptor development activities, established a work group for educational research and scholarship, and provided opportunities for networking and professional development. Several consortium members have received national recognition for their individual experiential education accomplishments. Through the activities of a regional consortium, members have successfully developed programs and initiatives that have streamlined administrative processes and have the potential to improve overall quality of experiential education programs. Professionally, consortium activities have resulted in 5 national presentations. PMID:18698386

Implementing non-invasive prenatal testing for aneuploidy in a national healthcare system: global challenges and national solutions.

PubMed

van Schendel, Rachèl V; van El, Carla G; Pajkrt, Eva; Henneman, Lidewij; Cornel, Martina C

2017-09-19

Since the introduction of non-invasive prenatal testing (NIPT) in 2011, mainly by commercial companies, a growing demand for NIPT from the public and healthcare professionals has been putting pressure on the healthcare systems of various countries. This study identifies the challenges of establishing a responsible implementation of NIPT for aneuploidy in prenatal healthcare, by looking at the Netherlands. A mixed methods approach involving 13 stakeholder interviews, document analysis and (participatory) observations of the Dutch NIPT Consortium meetings were used. The Diffusion of Innovation Theory and a Network of Actors model were used to interpret the findings. Implementation of NIPT was facilitated by several factors. The set-up of a national NIPT Consortium enabled discussion and collaboration between stakeholders. Moreover, it led to the plan to offer NIPT through a nationwide research setting (TRIDENT studies), which created a learning phase for careful implementation. The Dutch legal context was perceived as a delaying factor, but eventually gave room for the parties involved to organise themselves and their practices. This study shows that implementing advanced technologies with profound effects on prenatal care benefit from a learning phase that allows time to carefully evaluate the technical performance and women's experiences and to enable public debate. Such a coordinated learning phase, involving all stakeholders, will stimulate the process of responsible and sustainable implementation.

CSP Manufacturing Challenges and Assembly Reliability

NASA Technical Reports Server (NTRS)

Ghaffarian, Reza

2000-01-01

Although the expression of CSP is widely used by industry from suppliers to users, its implied definition had evolved as the technology has matured. There are "expert definition"- package that is up to 1.5 time die- or "interim definition". CSPs are miniature new packages that industry is starting to implement and there are many unresolved technical issues associated with their implementation. For example, in early 1997, packages with 1 mm pitch and lower were the dominant CSPs, whereas in early 1998 packages with 0.8 mm and lower became the norm for CSPs. Other changes included the use of flip chip die rather than wire bond in CSP. Nonetheless the emerging CSPs are competing with bare die assemblies and are becoming the package of choice for size reduction applications. These packages provide the benefits of small size and performance of the bare die or flip chip, with the advantage of standard die packages. The JPL-led MicrotypeBGA Consortium of enterprises representing government agencies and private companies have jointed together to pool in-kind resources for developing the quality and reliability of chip scale packages (CSPs) for a variety of projects. This talk will cover specifically the experience of our consortium on technology implementation challenges, including design and build of both standard and microvia boards, assembly of two types of test vehicles, and the most current environmental thermal cycling test results.

Multiphysics Application Coupling Toolkit

DOE Office of Scientific and Technical Information (OSTI.GOV)

Campbell, Michael T.

2013-12-02

This particular consortium implementation of the software integration infrastructure will, in large part, refactor portions of the Rocstar multiphysics infrastructure. Development of this infrastructure originated at the University of Illinois DOE ASCI Center for Simulation of Advanced Rockets (CSAR) to support the center's massively parallel multiphysics simulation application, Rocstar, and has continued at IllinoisRocstar, a small company formed near the end of the University-based program. IllinoisRocstar is now licensing these new developments as free, open source, in hopes to help improve their own and others' access to infrastructure which can be readily utilized in developing coupled or composite software systems;more » with particular attention to more rapid production and utilization of multiphysics applications in the HPC environment. There are two major pieces to the consortium implementation, the Application Component Toolkit (ACT), and the Multiphysics Application Coupling Toolkit (MPACT). The current development focus is the ACT, which is (will be) the substrate for MPACT. The ACT itself is built up from the components described in the technical approach. In particular, the ACT has the following major components: 1.The Component Object Manager (COM): The COM package provides encapsulation of user applications, and their data. COM also provides the inter-component function call mechanism. 2.The System Integration Manager (SIM): The SIM package provides constructs and mechanisms for orchestrating composite systems of multiply integrated pieces.« less

Value added phytoremediation of metal stressed soils using phosphate solubilizing microbial consortium.

PubMed

Gupta, Pratishtha; Kumar, Vipin

2017-01-01

The presence of heavy metals in the soil is a matter of growing concern due to their toxic and non-biodegradable nature. Lack of effectiveness of various conventional methods due to economic and technical constraints resulted in the search for an eco-friendly and cost-effective biological techniques for heavy metal removal from the environment. Until now, phytoremediation has emerged as an innovative technique to address the problem. However, the efficiency of phytoremediation process is hindered under the high metal concentration conditions. Hence, phosphate solubilizing microbes (PSM) assisted phytoremediation technique is gaining more insight as it can reduce the contamination load even under elevated metal stressed conditions. These microbes convert heavy metals into soluble and bioavailable forms, which consequently facilitate phytoremediation. Several studies have reported that the use of microbial consortium for remediation is considered more effective as compared to single strain pure culture. Therefore, this review paper focuses on the current trends in research related to PSM mediated uptake of heavy metal by plants. The efficiency of PSM consortia in enhancing the phytoremediation process has also been reviewed. Moreover, the role of phosphatase enzymes in the mineralization of organic forms of phosphate in soil is further discussed. Biosurfactant mediated bioremediation of metal polluted soils is a matter of extensive research nowadays. Hence, the recent advancement of using biosurfactants in enhanced phytoremediation of metal stressed soils is also described.

Southeast Clinical Oncology Research Consortium, Inc. (SCOR) | Division of Cancer Prevention

Cancer.gov

The SCCC-Upstate is a merger of two successful legacy CCOPs known as Southeast Cancer Control Consortium, Inc. (SCCC) and Upstate Carolina (hereafter the Consortium) comprised of 23 components and 63 sub-components, located in a five-state area of the Southeast US (GA, NC, SC, TN, and VA) with a nonclinical Administrative Office (AO) in Winston-Salem, NC. The Consortium

25 CFR 1000.390 - How can a Tribe/Consortium hire a Federal employee to help implement an AFA?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false How can a Tribe/Consortium hire a Federal employee to help implement an AFA? 1000.390 Section 1000.390 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN... Tribe/Consortium hire a Federal employee to help implement an AFA? If a Tribe/Consortium chooses to hire...

25 CFR 1000.390 - How can a Tribe/Consortium hire a Federal employee to help implement an AFA?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false How can a Tribe/Consortium hire a Federal employee to help implement an AFA? 1000.390 Section 1000.390 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN... Tribe/Consortium hire a Federal employee to help implement an AFA? If a Tribe/Consortium chooses to hire...

45 CFR 287.25 - May Tribes form a consortium to operate a NEW Program?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 2 2014-10-01 2012-10-01 true May Tribes form a consortium to operate a NEW... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.25 May Tribes form a consortium to operate a NEW Program? (a) Yes, as long as each Tribe forming the consortium is an “eligible Indian tribe...

45 CFR 287.25 - May Tribes form a consortium to operate a NEW Program?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true May Tribes form a consortium to operate a NEW... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.25 May Tribes form a consortium to operate a NEW Program? (a) Yes, as long as each Tribe forming the consortium is an “eligible Indian tribe...

45 CFR 287.25 - May Tribes form a consortium to operate a NEW Program?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false May Tribes form a consortium to operate a NEW... SERVICES THE NATIVE EMPLOYMENT WORKS (NEW) PROGRAM Eligible Tribes § 287.25 May Tribes form a consortium to operate a NEW Program? (a) Yes, as long as each Tribe forming the consortium is an “eligible Indian tribe...

AFT-QuEST Consortium Yearbook. Proceedings of the QuEST Consortium (April 2-6, 1972).

ERIC Educational Resources Information Center

American Federation of Teachers, Washington, DC.

This book contains the proceedings from the QuEST Consortium held on April 2-6, 1972, which focused on problems of method and technique in teaching as well as on resource organization. The program schedule for the Consortium is presented with the following goals: (a) investigation of educational policy issues, action programs, and projects and (b)…

The association of traumatic brain injury with rate of progression of cognitive and functional impairment in a population-based cohort of Alzheimer's disease: the Cache County Dementia Progression Study.

PubMed

Gilbert, Mac; Snyder, Christine; Corcoran, Chris; Norton, Maria C; Lyketsos, Constantine G; Tschanz, JoAnn T

2014-10-01

There is limited research on factors that influence the rate of progression in Alzheimer's disease (AD). A history of traumatic brain injury (TBI) is associated with an increased risk for AD, but its role on the rate of dementia progression after the onset of AD has not been examined. A population-based cohort of 325 persons with incident AD was followed for up to 11 years. The sample was 65% female with a mean (SD) age of dementia onset = 84.4 (6.4) years. History of TBI was categorized as number, severity (with or without loss of consciousness), and timing in relation to dementia onset (within ten years or more than ten years). Cognition was assessed by the Consortium to Establish a Registry of AD battery, and functional ability was assessed by the Clinical Dementia Rating Sum of Boxes. In linear mixed models, a history of TBI within ten years of onset showed faster progression of functional impairment (LR x2 = 10.27, p = 0.006), while those with TBI more than ten years before dementia onset had higher scores on a measure of list learning (β = 1.61, p = 0.003) and semantic memory (β = 0.75, p = 0.0035). History of TBI and its recency may be a useful factor to predict functional progression in the course of AD.

Long-Range Trends in the Development of Higher Education in Mining

ERIC Educational Resources Information Center

Pzhevskii, V. V.

1978-01-01

Reviews the relationship between scientific and technological progress, needs of the Soviet economy, and capacities of higher education institutions in terms of the future of the mining industry. Mining specialists will have to prepare for technical progress in the extracting industries, growth in production, complex mechanization, and automation…

Progress Monitoring in Middle School Mathematics: Options and Issues

ERIC Educational Resources Information Center

Foegen, Anne

2008-01-01

This study investigated the technical features of six potential progress-monitoring measures in mathematics appropriate for use at the middle school level, including two commercially available measures for sixth-grade mathematics, two measures used in previous middle school studies, and two new measures of numeracy concepts. Five hundred…

10 CFR 600.341 - Monitoring and reporting program and financial performance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... will be taken to address the deviations. (2) A final technical report if the award is for research and... dates for reports. At a minimum, requirements must include: (1) Periodic progress reports (at least... follows: (i) The program portions of the reports must address progress toward achieving program...

10 CFR 600.341 - Monitoring and reporting program and financial performance.

Code of Federal Regulations, 2014 CFR

2014-01-01

... will be taken to address the deviations. (2) A final technical report if the award is for research and... dates for reports. At a minimum, requirements must include: (1) Periodic progress reports (at least... follows: (i) The program portions of the reports must address progress toward achieving program...

10 CFR 600.341 - Monitoring and reporting program and financial performance.

Code of Federal Regulations, 2013 CFR

2013-01-01

... will be taken to address the deviations. (2) A final technical report if the award is for research and... dates for reports. At a minimum, requirements must include: (1) Periodic progress reports (at least... follows: (i) The program portions of the reports must address progress toward achieving program...

10 CFR 600.341 - Monitoring and reporting program and financial performance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... will be taken to address the deviations. (2) A final technical report if the award is for research and... dates for reports. At a minimum, requirements must include: (1) Periodic progress reports (at least... follows: (i) The program portions of the reports must address progress toward achieving program...