Sample records for constructing majority-rule supertrees

  1. Supertrees Based on the Subtree Prune-and-Regraft Distance

    PubMed Central

    Whidden, Christopher; Zeh, Norbert; Beiko, Robert G.

    2014-01-01

    Supertree methods reconcile a set of phylogenetic trees into a single structure that is often interpreted as a branching history of species. A key challenge is combining conflicting evolutionary histories that are due to artifacts of phylogenetic reconstruction and phenomena such as lateral gene transfer (LGT). Many supertree approaches use optimality criteria that do not reflect underlying processes, have known biases, and may be unduly influenced by LGT. We present the first method to construct supertrees by using the subtree prune-and-regraft (SPR) distance as an optimality criterion. Although calculating the rooted SPR distance between a pair of trees is NP-hard, our new maximum agreement forest-based methods can reconcile trees with hundreds of taxa and > 50 transfers in fractions of a second, which enables repeated calculations during the course of an iterative search. Our approach can accommodate trees in which uncertain relationships have been collapsed to multifurcating nodes. Using a series of benchmark datasets simulated under plausible rates of LGT, we show that SPR supertrees are more similar to correct species histories than supertrees based on parsimony or Robinson–Foulds distance criteria. We successfully constructed an SPR supertree from a phylogenomic dataset of 40,631 gene trees that covered 244 genomes representing several major bacterial phyla. Our SPR-based approach also allowed direct inference of highways of gene transfer between bacterial classes and genera. A Small number of these highways connect genera in different phyla and can highlight specific genes implicated in long-distance LGT. [Lateral gene transfer; matrix representation with parsimony; phylogenomics; prokaryotic phylogeny; Robinson–Foulds; subtree prune-and-regraft; supertrees.] PMID:24695589

  2. A supertree pipeline for summarizing phylogenetic and taxonomic information for millions of species

    PubMed Central

    Redelings, Benjamin D.

    2017-01-01

    We present a new supertree method that enables rapid estimation of a summary tree on the scale of millions of leaves. This supertree method summarizes a collection of input phylogenies and an input taxonomy. We introduce formal goals and criteria for such a supertree to satisfy in order to transparently and justifiably represent the input trees. In addition to producing a supertree, our method computes annotations that describe which grouping in the input trees support and conflict with each group in the supertree. We compare our supertree construction method to a previously published supertree construction method by assessing their performance on input trees used to construct the Open Tree of Life version 4, and find that our method increases the number of displayed input splits from 35,518 to 39,639 and decreases the number of conflicting input splits from 2,760 to 1,357. The new supertree method also improves on the previous supertree construction method in that it produces no unsupported branches and avoids unnecessary polytomies. This pipeline is currently used by the Open Tree of Life project to produce all of the versions of project’s “synthetic tree” starting at version 5. This software pipeline is called “propinquity”. It relies heavily on “otcetera”—a set of C++ tools to perform most of the steps of the pipeline. All of the components are free software and are available on GitHub. PMID:28265520

  3. Polynomial Supertree Methods Revisited

    PubMed Central

    Brinkmeyer, Malte; Griebel, Thasso; Böcker, Sebastian

    2011-01-01

    Supertree methods allow to reconstruct large phylogenetic trees by combining smaller trees with overlapping leaf sets into one, more comprehensive supertree. The most commonly used supertree method, matrix representation with parsimony (MRP), produces accurate supertrees but is rather slow due to the underlying hard optimization problem. In this paper, we present an extensive simulation study comparing the performance of MRP and the polynomial supertree methods MinCut Supertree, Modified MinCut Supertree, Build-with-distances, PhySIC, PhySIC_IST, and super distance matrix. We consider both quality and resolution of the reconstructed supertrees. Our findings illustrate the tradeoff between accuracy and running time in supertree construction, as well as the pros and cons of voting- and veto-based supertree approaches. Based on our results, we make some general suggestions for supertree methods yet to come. PMID:22229028

  4. Analyzing and synthesizing phylogenies using tree alignment graphs.

    PubMed

    Smith, Stephen A; Brown, Joseph W; Hinchliff, Cody E

    2013-01-01

    Phylogenetic trees are used to analyze and visualize evolution. However, trees can be imperfect datatypes when summarizing multiple trees. This is especially problematic when accommodating for biological phenomena such as horizontal gene transfer, incomplete lineage sorting, and hybridization, as well as topological conflict between datasets. Additionally, researchers may want to combine information from sets of trees that have partially overlapping taxon sets. To address the problem of analyzing sets of trees with conflicting relationships and partially overlapping taxon sets, we introduce methods for aligning, synthesizing and analyzing rooted phylogenetic trees within a graph, called a tree alignment graph (TAG). The TAG can be queried and analyzed to explore uncertainty and conflict. It can also be synthesized to construct trees, presenting an alternative to supertrees approaches. We demonstrate these methods with two empirical datasets. In order to explore uncertainty, we constructed a TAG of the bootstrap trees from the Angiosperm Tree of Life project. Analysis of the resulting graph demonstrates that areas of the dataset that are unresolved in majority-rule consensus tree analyses can be understood in more detail within the context of a graph structure, using measures incorporating node degree and adjacency support. As an exercise in synthesis (i.e., summarization of a TAG constructed from the alignment trees), we also construct a TAG consisting of the taxonomy and source trees from a recent comprehensive bird study. We synthesized this graph into a tree that can be reconstructed in a repeatable fashion and where the underlying source information can be updated. The methods presented here are tractable for large scale analyses and serve as a basis for an alternative to consensus tree and supertree methods. Furthermore, the exploration of these graphs can expose structures and patterns within the dataset that are otherwise difficult to observe.

  5. Analyzing and Synthesizing Phylogenies Using Tree Alignment Graphs

    PubMed Central

    Smith, Stephen A.; Brown, Joseph W.; Hinchliff, Cody E.

    2013-01-01

    Phylogenetic trees are used to analyze and visualize evolution. However, trees can be imperfect datatypes when summarizing multiple trees. This is especially problematic when accommodating for biological phenomena such as horizontal gene transfer, incomplete lineage sorting, and hybridization, as well as topological conflict between datasets. Additionally, researchers may want to combine information from sets of trees that have partially overlapping taxon sets. To address the problem of analyzing sets of trees with conflicting relationships and partially overlapping taxon sets, we introduce methods for aligning, synthesizing and analyzing rooted phylogenetic trees within a graph, called a tree alignment graph (TAG). The TAG can be queried and analyzed to explore uncertainty and conflict. It can also be synthesized to construct trees, presenting an alternative to supertrees approaches. We demonstrate these methods with two empirical datasets. In order to explore uncertainty, we constructed a TAG of the bootstrap trees from the Angiosperm Tree of Life project. Analysis of the resulting graph demonstrates that areas of the dataset that are unresolved in majority-rule consensus tree analyses can be understood in more detail within the context of a graph structure, using measures incorporating node degree and adjacency support. As an exercise in synthesis (i.e., summarization of a TAG constructed from the alignment trees), we also construct a TAG consisting of the taxonomy and source trees from a recent comprehensive bird study. We synthesized this graph into a tree that can be reconstructed in a repeatable fashion and where the underlying source information can be updated. The methods presented here are tractable for large scale analyses and serve as a basis for an alternative to consensus tree and supertree methods. Furthermore, the exploration of these graphs can expose structures and patterns within the dataset that are otherwise difficult to observe. PMID:24086118

  6. Towards a Supertree of Arthropoda: A Species-Level Supertree of the Spiny, Slipper and Coral Lobsters (Decapoda: Achelata)

    PubMed Central

    Davis, Katie E.; Hesketh, Thomas W.; Delmer, Cyrille; Wills, Matthew A.

    2015-01-01

    While supertrees have been built for many vertebrate groups (notably birds, mammals and dinosaurs), invertebrates have attracted relatively little attention. The paucity of supertrees of arthropods is particularly surprising given their economic and ecological importance, as well as their overwhelming contribution to biodiversity. The absence of comprehensive archives of machine-readable source trees, coupled with the need for software implementing repeatable protocols for managing them, has undoubtedly impeded progress. Here we present a supertree of Achelata (spiny, slipper and coral lobsters) as a proof of concept, constructed using new supertree specific software (the Supertree Toolkit; STK) and following a published protocol. We also introduce a new resource for archiving and managing published source trees. Our supertree of Achelata is synthesised from morphological and molecular source trees, and represents the most complete species-level tree of the group to date. Our findings are consistent with recent taxonomic treatments, confirming the validity of just two families: Palinuridae and Scyllaridae; Synaxidae were resolved within Palinuridae. Monophyletic Silentes and Stridentes lineages are recovered within Palinuridae, and all sub-families within Scyllaridae are found to be monophyletic with the exception of Ibacinae. We demonstrate the feasibility of building larger supertrees of arthropods, with the ultimate objective of building a complete species-level phylogeny for the entire phylum using a divide and conquer strategy. PMID:26461106

  7. Towards a Supertree of Arthropoda: A Species-Level Supertree of the Spiny, Slipper and Coral Lobsters (Decapoda: Achelata).

    PubMed

    Davis, Katie E; Hesketh, Thomas W; Delmer, Cyrille; Wills, Matthew A

    2015-01-01

    While supertrees have been built for many vertebrate groups (notably birds, mammals and dinosaurs), invertebrates have attracted relatively little attention. The paucity of supertrees of arthropods is particularly surprising given their economic and ecological importance, as well as their overwhelming contribution to biodiversity. The absence of comprehensive archives of machine-readable source trees, coupled with the need for software implementing repeatable protocols for managing them, has undoubtedly impeded progress. Here we present a supertree of Achelata (spiny, slipper and coral lobsters) as a proof of concept, constructed using new supertree specific software (the Supertree Toolkit; STK) and following a published protocol. We also introduce a new resource for archiving and managing published source trees. Our supertree of Achelata is synthesised from morphological and molecular source trees, and represents the most complete species-level tree of the group to date. Our findings are consistent with recent taxonomic treatments, confirming the validity of just two families: Palinuridae and Scyllaridae; Synaxidae were resolved within Palinuridae. Monophyletic Silentes and Stridentes lineages are recovered within Palinuridae, and all sub-families within Scyllaridae are found to be monophyletic with the exception of Ibacinae. We demonstrate the feasibility of building larger supertrees of arthropods, with the ultimate objective of building a complete species-level phylogeny for the entire phylum using a divide and conquer strategy.

  8. A fungal phylogeny based on 42 complete genomes derived from supertree and combined gene analysis

    PubMed Central

    Fitzpatrick, David A; Logue, Mary E; Stajich, Jason E; Butler, Geraldine

    2006-01-01

    Background To date, most fungal phylogenies have been derived from single gene comparisons, or from concatenated alignments of a small number of genes. The increase in fungal genome sequencing presents an opportunity to reconstruct evolutionary events using entire genomes. As a tool for future comparative, phylogenomic and phylogenetic studies, we used both supertrees and concatenated alignments to infer relationships between 42 species of fungi for which complete genome sequences are available. Results A dataset of 345,829 genes was extracted from 42 publicly available fungal genomes. Supertree methods were employed to derive phylogenies from 4,805 single gene families. We found that the average consensus supertree method may suffer from long-branch attraction artifacts, while matrix representation with parsimony (MRP) appears to be immune from these. A genome phylogeny was also reconstructed from a concatenated alignment of 153 universally distributed orthologs. Our MRP supertree and concatenated phylogeny are highly congruent. Within the Ascomycota, the sub-phyla Pezizomycotina and Saccharomycotina were resolved. Both phylogenies infer that the Leotiomycetes are the closest sister group to the Sordariomycetes. There is some ambiguity regarding the placement of Stagonospora nodurum, the sole member of the class Dothideomycetes present in the dataset. Within the Saccharomycotina, a monophyletic clade containing organisms that translate CTG as serine instead of leucine is evident. There is also strong support for two groups within the CTG clade, one containing the fully sexual species Candida lusitaniae, Candida guilliermondii and Debaryomyces hansenii, and the second group containing Candida albicans, Candida dubliniensis, Candida tropicalis, Candida parapsilosis and Lodderomyces elongisporus. The second major clade within the Saccharomycotina contains species whose genomes have undergone a whole genome duplication (WGD), and their close relatives. We could not confidently resolve whether Candida glabrata or Saccharomyces castellii lies at the base of the WGD clade. Conclusion We have constructed robust phylogenies for fungi based on whole genome analysis. Overall, our phylogenies provide strong support for the classification of phyla, sub-phyla, classes and orders. We have resolved the relationship of the classes Leotiomyctes and Sordariomycetes, and have identified two classes within the CTG clade of the Saccharomycotina that may correlate with sexual status. PMID:17121679

  9. The Supertree Toolkit 2: a new and improved software package with a Graphical User Interface for supertree construction.

    PubMed

    Hill, Jon; Davis, Katie E

    2014-01-01

    Building large supertrees involves the collection, storage, and processing of thousands of individual phylogenies to create large phylogenies with thousands to tens of thousands of taxa. Such large phylogenies are useful for macroevolutionary studies, comparative biology and in conservation and biodiversity. No easy to use and fully integrated software package currently exists to carry out this task. Here, we present a new Python-based software package that uses well defined XML schema to manage both data and metadata. It builds on previous versions by 1) including new processing steps, such as Safe Taxonomic Reduction, 2) using a user-friendly GUI that guides the user to complete at least the minimum information required and includes context-sensitive documentation, and 3) a revised storage format that integrates both tree- and meta-data into a single file. These data can then be manipulated according to a well-defined, but flexible, processing pipeline using either the GUI or a command-line based tool. Processing steps include standardising names, deleting or replacing taxa, ensuring adequate taxonomic overlap, ensuring data independence, and safe taxonomic reduction. This software has been successfully used to store and process data consisting of over 1000 trees ready for analyses using standard supertree methods. This software makes large supertree creation a much easier task and provides far greater flexibility for further work.

  10. Triplet supertree heuristics for the tree of life

    PubMed Central

    Lin, Harris T; Burleigh, J Gordon; Eulenstein, Oliver

    2009-01-01

    Background There is much interest in developing fast and accurate supertree methods to infer the tree of life. Supertree methods combine smaller input trees with overlapping sets of taxa to make a comprehensive phylogenetic tree that contains all of the taxa in the input trees. The intrinsically hard triplet supertree problem takes a collection of input species trees and seeks a species tree (supertree) that maximizes the number of triplet subtrees that it shares with the input trees. However, the utility of this supertree problem has been limited by a lack of efficient and effective heuristics. Results We introduce fast hill-climbing heuristics for the triplet supertree problem that perform a step-wise search of the tree space, where each step is guided by an exact solution to an instance of a local search problem. To realize time efficient heuristics we designed the first nontrivial algorithms for two standard search problems, which greatly improve on the time complexity to the best known (naïve) solutions by a factor of n and n2 (the number of taxa in the supertree). These algorithms enable large-scale supertree analyses based on the triplet supertree problem that were previously not possible. We implemented hill-climbing heuristics that are based on our new algorithms, and in analyses of two published supertree data sets, we demonstrate that our new heuristics outperform other standard supertree methods in maximizing the number of triplets shared with the input trees. Conclusion With our new heuristics, the triplet supertree problem is now computationally more tractable for large-scale supertree analyses, and it provides a potentially more accurate alternative to existing supertree methods. PMID:19208181

  11. Updating the evolutionary history of Carnivora (Mammalia): a new species-level supertree complete with divergence time estimates

    PubMed Central

    2012-01-01

    Background Although it has proven to be an important foundation for investigations of carnivoran ecology, biology and evolution, the complete species-level supertree for Carnivora of Bininda-Emonds et al. is showing its age. Additional, largely molecular sequence data are now available for many species and the advancement of computer technology means that many of the limitations of the original analysis can now be avoided. We therefore sought to provide an updated estimate of the phylogenetic relationships within all extant Carnivora, again using supertree analysis to be able to analyze as much of the global phylogenetic database for the group as possible. Results In total, 188 source trees were combined, representing 114 trees from the literature together with 74 newly constructed gene trees derived from nearly 45,000 bp of sequence data from GenBank. The greater availability of sequence data means that the new supertree is almost completely resolved and also better reflects current phylogenetic opinion (for example, supporting a monophyletic Mephitidae, Eupleridae and Prionodontidae; placing Nandinia binotata as sister to the remaining Feliformia). Following an initial rapid radiation, diversification rate analyses indicate a downturn in the net speciation rate within the past three million years as well as a possible increase some 18.0 million years ago; numerous diversification rate shifts within the order were also identified. Conclusions Together, the two carnivore supertrees remain the only complete phylogenetic estimates for all extant species and the new supertree, like the old one, will form a key tool in helping us to further understand the biology of this charismatic group of carnivores. PMID:22369503

  12. The Supertree Toolkit 2: a new and improved software package with a Graphical User Interface for supertree construction

    PubMed Central

    2014-01-01

    Abstract Building large supertrees involves the collection, storage, and processing of thousands of individual phylogenies to create large phylogenies with thousands to tens of thousands of taxa. Such large phylogenies are useful for macroevolutionary studies, comparative biology and in conservation and biodiversity. No easy to use and fully integrated software package currently exists to carry out this task. Here, we present a new Python-based software package that uses well defined XML schema to manage both data and metadata. It builds on previous versions by 1) including new processing steps, such as Safe Taxonomic Reduction, 2) using a user-friendly GUI that guides the user to complete at least the minimum information required and includes context-sensitive documentation, and 3) a revised storage format that integrates both tree- and meta-data into a single file. These data can then be manipulated according to a well-defined, but flexible, processing pipeline using either the GUI or a command-line based tool. Processing steps include standardising names, deleting or replacing taxa, ensuring adequate taxonomic overlap, ensuring data independence, and safe taxonomic reduction. This software has been successfully used to store and process data consisting of over 1000 trees ready for analyses using standard supertree methods. This software makes large supertree creation a much easier task and provides far greater flexibility for further work. PMID:24891820

  13. BCD Beam Search: considering suboptimal partial solutions in Bad Clade Deletion supertrees.

    PubMed

    Fleischauer, Markus; Böcker, Sebastian

    2018-01-01

    Supertree methods enable the reconstruction of large phylogenies. The supertree problem can be formalized in different ways in order to cope with contradictory information in the input. Some supertree methods are based on encoding the input trees in a matrix; other methods try to find minimum cuts in some graph. Recently, we introduced Bad Clade Deletion (BCD) supertrees which combines the graph-based computation of minimum cuts with optimizing a global objective function on the matrix representation of the input trees. The BCD supertree method has guaranteed polynomial running time and is very swift in practice. The quality of reconstructed supertrees was superior to matrix representation with parsimony (MRP) and usually on par with SuperFine for simulated data; but particularly for biological data, quality of BCD supertrees could not keep up with SuperFine supertrees. Here, we present a beam search extension for the BCD algorithm that keeps alive a constant number of partial solutions in each top-down iteration phase. The guaranteed worst-case running time of the new algorithm is still polynomial in the size of the input. We present an exact and a randomized subroutine to generate suboptimal partial solutions. Both beam search approaches consistently improve supertree quality on all evaluated datasets when keeping 25 suboptimal solutions alive. Supertree quality of the BCD Beam Search algorithm is on par with MRP and SuperFine even for biological data. This is the best performance of a polynomial-time supertree algorithm reported so far.

  14. PhySIC_IST: cleaning source trees to infer more informative supertrees

    PubMed Central

    Scornavacca, Celine; Berry, Vincent; Lefort, Vincent; Douzery, Emmanuel JP; Ranwez, Vincent

    2008-01-01

    Background Supertree methods combine phylogenies with overlapping sets of taxa into a larger one. Topological conflicts frequently arise among source trees for methodological or biological reasons, such as long branch attraction, lateral gene transfers, gene duplication/loss or deep gene coalescence. When topological conflicts occur among source trees, liberal methods infer supertrees containing the most frequent alternative, while veto methods infer supertrees not contradicting any source tree, i.e. discard all conflicting resolutions. When the source trees host a significant number of topological conflicts or have a small taxon overlap, supertree methods of both kinds can propose poorly resolved, hence uninformative, supertrees. Results To overcome this problem, we propose to infer non-plenary supertrees, i.e. supertrees that do not necessarily contain all the taxa present in the source trees, discarding those whose position greatly differs among source trees or for which insufficient information is provided. We detail a variant of the PhySIC veto method called PhySIC_IST that can infer non-plenary supertrees. PhySIC_IST aims at inferring supertrees that satisfy the same appealing theoretical properties as with PhySIC, while being as informative as possible under this constraint. The informativeness of a supertree is estimated using a variation of the CIC (Cladistic Information Content) criterion, that takes into account both the presence of multifurcations and the absence of some taxa. Additionally, we propose a statistical preprocessing step called STC (Source Trees Correction) to correct the source trees prior to the supertree inference. STC is a liberal step that removes the parts of each source tree that significantly conflict with other source trees. Combining STC with a veto method allows an explicit trade-off between veto and liberal approaches, tuned by a single parameter. Performing large-scale simulations, we observe that STC+PhySIC_IST infers much more informative supertrees than PhySIC, while preserving low type I error compared to the well-known MRP method. Two biological case studies on animals confirm that the STC preprocess successfully detects anomalies in the source trees while STC+PhySIC_IST provides well-resolved supertrees agreeing with current knowledge in systematics. Conclusion The paper introduces and tests two new methodologies, PhySIC_IST and STC, that demonstrate the interest in inferring non-plenary supertrees as well as preprocessing the source trees. An implementation of the methods is available at: . PMID:18834542

  15. PhySIC_IST: cleaning source trees to infer more informative supertrees.

    PubMed

    Scornavacca, Celine; Berry, Vincent; Lefort, Vincent; Douzery, Emmanuel J P; Ranwez, Vincent

    2008-10-04

    Supertree methods combine phylogenies with overlapping sets of taxa into a larger one. Topological conflicts frequently arise among source trees for methodological or biological reasons, such as long branch attraction, lateral gene transfers, gene duplication/loss or deep gene coalescence. When topological conflicts occur among source trees, liberal methods infer supertrees containing the most frequent alternative, while veto methods infer supertrees not contradicting any source tree, i.e. discard all conflicting resolutions. When the source trees host a significant number of topological conflicts or have a small taxon overlap, supertree methods of both kinds can propose poorly resolved, hence uninformative, supertrees. To overcome this problem, we propose to infer non-plenary supertrees, i.e. supertrees that do not necessarily contain all the taxa present in the source trees, discarding those whose position greatly differs among source trees or for which insufficient information is provided. We detail a variant of the PhySIC veto method called PhySIC_IST that can infer non-plenary supertrees. PhySIC_IST aims at inferring supertrees that satisfy the same appealing theoretical properties as with PhySIC, while being as informative as possible under this constraint. The informativeness of a supertree is estimated using a variation of the CIC (Cladistic Information Content) criterion, that takes into account both the presence of multifurcations and the absence of some taxa. Additionally, we propose a statistical preprocessing step called STC (Source Trees Correction) to correct the source trees prior to the supertree inference. STC is a liberal step that removes the parts of each source tree that significantly conflict with other source trees. Combining STC with a veto method allows an explicit trade-off between veto and liberal approaches, tuned by a single parameter.Performing large-scale simulations, we observe that STC+PhySIC_IST infers much more informative supertrees than PhySIC, while preserving low type I error compared to the well-known MRP method. Two biological case studies on animals confirm that the STC preprocess successfully detects anomalies in the source trees while STC+PhySIC_IST provides well-resolved supertrees agreeing with current knowledge in systematics. The paper introduces and tests two new methodologies, PhySIC_IST and STC, that demonstrate the interest in inferring non-plenary supertrees as well as preprocessing the source trees. An implementation of the methods is available at: http://www.atgc-montpellier.fr/physic_ist/.

  16. L.U.St: a tool for approximated maximum likelihood supertree reconstruction.

    PubMed

    Akanni, Wasiu A; Creevey, Christopher J; Wilkinson, Mark; Pisani, Davide

    2014-06-12

    Supertrees combine disparate, partially overlapping trees to generate a synthesis that provides a high level perspective that cannot be attained from the inspection of individual phylogenies. Supertrees can be seen as meta-analytical tools that can be used to make inferences based on results of previous scientific studies. Their meta-analytical application has increased in popularity since it was realised that the power of statistical tests for the study of evolutionary trends critically depends on the use of taxon-dense phylogenies. Further to that, supertrees have found applications in phylogenomics where they are used to combine gene trees and recover species phylogenies based on genome-scale data sets. Here, we present the L.U.St package, a python tool for approximate maximum likelihood supertree inference and illustrate its application using a genomic data set for the placental mammals. L.U.St allows the calculation of the approximate likelihood of a supertree, given a set of input trees, performs heuristic searches to look for the supertree of highest likelihood, and performs statistical tests of two or more supertrees. To this end, L.U.St implements a winning sites test allowing ranking of a collection of a-priori selected hypotheses, given as a collection of input supertree topologies. It also outputs a file of input-tree-wise likelihood scores that can be used as input to CONSEL for calculation of standard tests of two trees (e.g. Kishino-Hasegawa, Shimidoara-Hasegawa and Approximately Unbiased tests). This is the first fully parametric implementation of a supertree method, it has clearly understood properties, and provides several advantages over currently available supertree approaches. It is easy to implement and works on any platform that has python installed. bitBucket page - https://afro-juju@bitbucket.org/afro-juju/l.u.st.git. Davide.Pisani@bristol.ac.uk.

  17. PhySIC: a veto supertree method with desirable properties.

    PubMed

    Ranwez, Vincent; Berry, Vincent; Criscuolo, Alexis; Fabre, Pierre-Henri; Guillemot, Sylvain; Scornavacca, Celine; Douzery, Emmanuel J P

    2007-10-01

    This paper focuses on veto supertree methods; i.e., methods that aim at producing a conservative synthesis of the relationships agreed upon by all source trees. We propose desirable properties that a supertree should satisfy in this framework, namely the non-contradiction property (PC) and the induction property (PI). The former requires that the supertree does not contain relationships that contradict one or a combination of the source topologies, whereas the latter requires that all topological information contained in the supertree is present in a source tree or collectively induced by several source trees. We provide simple examples to illustrate their relevance and that allow a comparison with previously advocated properties. We show that these properties can be checked in polynomial time for any given rooted supertree. Moreover, we introduce the PhySIC method (PHYlogenetic Signal with Induction and non-Contradiction). For k input trees spanning a set of n taxa, this method produces a supertree that satisfies the above-mentioned properties in O(kn(3) + n(4)) computing time. The polytomies of the produced supertree are also tagged by labels indicating areas of conflict as well as those with insufficient overlap. As a whole, PhySIC enables the user to quickly summarize consensual information of a set of trees and localize groups of taxa for which the data require consolidation. Lastly, we illustrate the behaviour of PhySIC on primate data sets of various sizes, and propose a supertree covering 95% of all primate extant genera. The PhySIC algorithm is available at http://atgc.lirmm.fr/cgi-bin/PhySIC.

  18. Reweaving the Tapestry: a Supertree of Birds

    PubMed Central

    Davis, Katie E; Page, Roderic D. M.

    2014-01-01

    Our knowledge of the avian tree of life remains uncertain, particularly at deeper levels due to the rapid diversification early in their evolutionary history. They are the most abundant land vertebrate on the planet and have been of great historical interest to systematists. Birds are also economically and ecologically important and as a result are intensively studied, yet despite their importance and interest to humans around 13% of taxa currently on the endangered species list perhaps as a result of human activity. Despite all this no comprehensive phylogeny that includes both extinct and extant species currently exists. Here we present a species-level supertree, constructed using the Matrix Representation with Parsimony method, of Aves containing approximately two thirds of all species from nearly 1000 source phylogenies with a broad taxonomic coverage. The source data for the tree were collected and processed according to a strict protocol to ensure robust and accurate data handling. The resulting tree topology is largely consistent with molecular hypotheses of avian phylogeny. We identify areas that are in broad agreement with current views on avian systematics and also those that require further work. We also highlight the need for leaf-based support measures to enable the identification of rogue taxa in supertrees. This is a first attempt at a supertree of both extinct and extant birds, it is not intended to be utilised in an overhaul of avian systematics or as a basis for taxonomic re-classification but provides a strong basis on which to base further studies on macroevolution, conservation, biodiversity, comparative biology and character evolution, in particular the inclusion of fossils will allow the study of bird evolution and diversification throughout deep time. PMID:24944845

  19. Accurate Phylogenetic Tree Reconstruction from Quartets: A Heuristic Approach

    PubMed Central

    Reaz, Rezwana; Bayzid, Md. Shamsuzzoha; Rahman, M. Sohel

    2014-01-01

    Supertree methods construct trees on a set of taxa (species) combining many smaller trees on the overlapping subsets of the entire set of taxa. A ‘quartet’ is an unrooted tree over taxa, hence the quartet-based supertree methods combine many -taxon unrooted trees into a single and coherent tree over the complete set of taxa. Quartet-based phylogeny reconstruction methods have been receiving considerable attentions in the recent years. An accurate and efficient quartet-based method might be competitive with the current best phylogenetic tree reconstruction methods (such as maximum likelihood or Bayesian MCMC analyses), without being as computationally intensive. In this paper, we present a novel and highly accurate quartet-based phylogenetic tree reconstruction method. We performed an extensive experimental study to evaluate the accuracy and scalability of our approach on both simulated and biological datasets. PMID:25117474

  20. MRL and SuperFine+MRL: new supertree methods

    PubMed Central

    2012-01-01

    Background Supertree methods combine trees on subsets of the full taxon set together to produce a tree on the entire set of taxa. Of the many supertree methods, the most popular is MRP (Matrix Representation with Parsimony), a method that operates by first encoding the input set of source trees by a large matrix (the "MRP matrix") over {0,1, ?}, and then running maximum parsimony heuristics on the MRP matrix. Experimental studies evaluating MRP in comparison to other supertree methods have established that for large datasets, MRP generally produces trees of equal or greater accuracy than other methods, and can run on larger datasets. A recent development in supertree methods is SuperFine+MRP, a method that combines MRP with a divide-and-conquer approach, and produces more accurate trees in less time than MRP. In this paper we consider a new approach for supertree estimation, called MRL (Matrix Representation with Likelihood). MRL begins with the same MRP matrix, but then analyzes the MRP matrix using heuristics (such as RAxML) for 2-state Maximum Likelihood. Results We compared MRP and SuperFine+MRP with MRL and SuperFine+MRL on simulated and biological datasets. We examined the MRP and MRL scores of each method on a wide range of datasets, as well as the resulting topological accuracy of the trees. Our experimental results show that MRL, coupled with a very good ML heuristic such as RAxML, produced more accurate trees than MRP, and MRL scores were more strongly correlated with topological accuracy than MRP scores. Conclusions SuperFine+MRP, when based upon a good MP heuristic, such as TNT, produces among the best scores for both MRP and MRL, and is generally faster and more topologically accurate than other supertree methods we tested. PMID:22280525

  1. Building supertrees: an empirical assessment using the grass family (Poaceae).

    PubMed

    Salamin, Nicolas; Hodkinson, Trevor R; Savolainen, Vincent

    2002-02-01

    Large and comprehensive phylogenetic trees are desirable for studying macroevolutionary processes and for classification purposes. Such trees can be obtained in two different ways. Either the widest possible range of taxa can be sampled and used in a phylogenetic analysis to produce a "big tree," or preexisting topologies can be used to create a supertree. Although large multigene analyses are often favored, combinable data are not always available, and supertrees offer a suitable solution. The most commonly used method of supertree reconstruction, matrix representation with parsimony (MRP), is presented here. We used a combined data set for the Poaceae to (1) assess the differences between an approach that uses combined data and one that uses different MRP modifications based on the character partitions and (2) investigate the advantages and disadvantages of these modifications. Baum and Ragan and Purvis modifications gave similar results. Incorporating bootstrap support associated with pre-existing topologies improved Baum and Ragan modification and its similarity with a combined analysis. Finally, we used the supertree reconstruction approach on 55 published phylogenies to build one of most comprehensive phylogenetic trees published for the grass family including 403 taxa and discuss its strengths and weaknesses in relation to other published hypotheses.

  2. Phylogeny and divergence of the pinnipeds (Carnivora: Mammalia) assessed using a multigene dataset

    PubMed Central

    Higdon, Jeff W; Bininda-Emonds, Olaf RP; Beck, Robin MD; Ferguson, Steven H

    2007-01-01

    Background Phylogenetic comparative methods are often improved by complete phylogenies with meaningful branch lengths (e.g., divergence dates). This study presents a dated molecular supertree for all 34 world pinniped species derived from a weighted matrix representation with parsimony (MRP) supertree analysis of 50 gene trees, each determined under a maximum likelihood (ML) framework. Divergence times were determined by mapping the same sequence data (plus two additional genes) on to the supertree topology and calibrating the ML branch lengths against a range of fossil calibrations. We assessed the sensitivity of our supertree topology in two ways: 1) a second supertree with all mtDNA genes combined into a single source tree, and 2) likelihood-based supermatrix analyses. Divergence dates were also calculated using a Bayesian relaxed molecular clock with rate autocorrelation to test the sensitivity of our supertree results further. Results The resulting phylogenies all agreed broadly with recent molecular studies, in particular supporting the monophyly of Phocidae, Otariidae, and the two phocid subfamilies, as well as an Odobenidae + Otariidae sister relationship; areas of disagreement were limited to four more poorly supported regions. Neither the supertree nor supermatrix analyses supported the monophyly of the two traditional otariid subfamilies, supporting suggestions for the need for taxonomic revision in this group. Phocid relationships were similar to other recent studies and deeper branches were generally well-resolved. Halichoerus grypus was nested within a paraphyletic Pusa, although relationships within Phocina tend to be poorly supported. Divergence date estimates for the supertree were in good agreement with other studies and the available fossil record; however, the Bayesian relaxed molecular clock divergence date estimates were significantly older. Conclusion Our results join other recent studies and highlight the need for a re-evaluation of pinniped taxonomy, especially as regards the subfamilial classification of otariids and the generic nomenclature of Phocina. Even with the recent publication of new sequence data, the available genetic sequence information for several species, particularly those in Arctocephalus, remains very limited, especially for nuclear markers. However, resolution of parts of the tree will probably remain difficult, even with additional data, due to apparent rapid radiations. Our study addresses the lack of a recent pinniped phylogeny that includes all species and robust divergence dates for all nodes, and will therefore prove indispensable to comparative and macroevolutionary studies of this group of carnivores. PMID:17996107

  3. Weed management at ArborGen, South Carolina SuperTree Nursery

    Treesearch

    Mike Arnette

    2009-01-01

    Weed management is vital to producing healthy hardwood seedlings. Several methods are available to each nursery, and it is common knowledge that what works for one situation may not work for another. The weed control methods used in nursery beds of hardwood species at the South Carolina SuperTree Nursery (Blenheim) are listed below.

  4. Human population history revealed by a supertree approach

    PubMed Central

    Duda, Pavel; Jan Zrzavý

    2016-01-01

    Over the past two decades numerous new trees of modern human populations have been published extensively but little attention has been paid to formal phylogenetic synthesis. We utilized the “matrix representation with parsimony” (MRP) method to infer a composite phylogeny (supertree) of modern human populations, based on 257 genetic/genomic, as well as linguistic, phylogenetic trees and 44 admixture plots from 200 published studies (1990–2014). The resulting supertree topology includes the most basal position of S African Khoisan followed by C African Pygmies, and the paraphyletic section of all other sub-Saharan peoples. The sub-Saharan African section is basal to the monophyletic clade consisting of the N African–W Eurasian assemblage and the consistently monophyletic Eastern superclade (Sahul–Oceanian, E Asian, and Beringian–American peoples). This topology, dominated by genetic data, is well-resolved and robust to parameter set changes, with a few unstable areas (e.g., West Eurasia, Sahul–Melanesia) reflecting the existing phylogenetic controversies. A few populations were identified as highly unstable “wildcard taxa” (e.g. Andamanese, Malagasy). The linguistic classification fits rather poorly on the supertree topology, supporting a view that direct coevolution between genes and languages is far from universal. PMID:27431856

  5. Efficient FPT Algorithms for (Strict) Compatibility of Unrooted Phylogenetic Trees.

    PubMed

    Baste, Julien; Paul, Christophe; Sau, Ignasi; Scornavacca, Celine

    2017-04-01

    In phylogenetics, a central problem is to infer the evolutionary relationships between a set of species X; these relationships are often depicted via a phylogenetic tree-a tree having its leaves labeled bijectively by elements of X and without degree-2 nodes-called the "species tree." One common approach for reconstructing a species tree consists in first constructing several phylogenetic trees from primary data (e.g., DNA sequences originating from some species in X), and then constructing a single phylogenetic tree maximizing the "concordance" with the input trees. The obtained tree is our estimation of the species tree and, when the input trees are defined on overlapping-but not identical-sets of labels, is called "supertree." In this paper, we focus on two problems that are central when combining phylogenetic trees into a supertree: the compatibility and the strict compatibility problems for unrooted phylogenetic trees. These problems are strongly related, respectively, to the notions of "containing as a minor" and "containing as a topological minor" in the graph community. Both problems are known to be fixed parameter tractable in the number of input trees k, by using their expressibility in monadic second-order logic and a reduction to graphs of bounded treewidth. Motivated by the fact that the dependency on k of these algorithms is prohibitively large, we give the first explicit dynamic programming algorithms for solving these problems, both running in time [Formula: see text], where n is the total size of the input.

  6. A supertree of early tetrapods.

    PubMed Central

    Ruta, Marcello; Jeffery, Jonathan E; Coates, Michael I

    2003-01-01

    A genus-level supertree for early tetrapods is built using a matrix representation of 50 source trees. The analysis of all combined trees delivers a long-stemmed topology in which most taxonomic groups are assigned to the tetrapod stem. A second analysis, which excludes source trees superseded by more comprehensive studies, supports a deep phylogenetic split between lissamphibian and amniote total groups. Instances of spurious groups are rare in both analyses. The results of the pruned second analysis are mostly comparable with those of a recent, character-based and large-scale phylogeny of Palaeozoic tetrapods. Outstanding areas of disagreement include the branching sequence of lepospondyls and the content of the amniote crown group, in particular the placement of diadectomorphs as stem diapsids. Supertrees are unsurpassed in their ability to summarize relationship patterns from multiple independent topologies. Therefore, they might be used as a simple test of the degree of corroboration of nodes in the contributory analyses. However, we urge caution in using them as a replacement for character-based cladograms and for inferring macroevolutionary patterns. PMID:14667343

  7. Reconstructing (super)trees from data sets with missing distances: not all is lost.

    PubMed

    Kettleborough, George; Dicks, Jo; Roberts, Ian N; Huber, Katharina T

    2015-06-01

    The wealth of phylogenetic information accumulated over many decades of biological research, coupled with recent technological advances in molecular sequence generation, presents significant opportunities for researchers to investigate relationships across and within the kingdoms of life. However, to make best use of this data wealth, several problems must first be overcome. One key problem is finding effective strategies to deal with missing data. Here, we introduce Lasso, a novel heuristic approach for reconstructing rooted phylogenetic trees from distance matrices with missing values, for data sets where a molecular clock may be assumed. Contrary to other phylogenetic methods on partial data sets, Lasso possesses desirable properties such as its reconstructed trees being both unique and edge-weighted. These properties are achieved by Lasso restricting its leaf set to a large subset of all possible taxa, which in many practical situations is the entire taxa set. Furthermore, the Lasso approach is distance-based, rendering it very fast to run and suitable for data sets of all sizes, including large data sets such as those generated by modern Next Generation Sequencing technologies. To better understand the performance of Lasso, we assessed it by means of artificial and real biological data sets, showing its effectiveness in the presence of missing data. Furthermore, by formulating the supermatrix problem as a particular case of the missing data problem, we assessed Lasso's ability to reconstruct supertrees. We demonstrate that, although not specifically designed for such a purpose, Lasso performs better than or comparably with five leading supertree algorithms on a challenging biological data set. Finally, we make freely available a software implementation of Lasso so that researchers may, for the first time, perform both rooted tree and supertree reconstruction with branch lengths on their own partial data sets. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  8. Comparing Phylogenetic Trees by Matching Nodes Using the Transfer Distance Between Partitions

    PubMed Central

    Giaro, Krzysztof

    2017-01-01

    Abstract Ability to quantify dissimilarity of different phylogenetic trees describing the relationship between the same group of taxa is required in various types of phylogenetic studies. For example, such metrics are used to assess the quality of phylogeny construction methods, to define optimization criteria in supertree building algorithms, or to find horizontal gene transfer (HGT) events. Among the set of metrics described so far in the literature, the most commonly used seems to be the Robinson–Foulds distance. In this article, we define a new metric for rooted trees—the Matching Pair (MP) distance. The MP metric uses the concept of the minimum-weight perfect matching in a complete bipartite graph constructed from partitions of all pairs of leaves of the compared phylogenetic trees. We analyze the properties of the MP metric and present computational experiments showing its potential applicability in tasks related to finding the HGT events. PMID:28177699

  9. Comparing Phylogenetic Trees by Matching Nodes Using the Transfer Distance Between Partitions.

    PubMed

    Bogdanowicz, Damian; Giaro, Krzysztof

    2017-05-01

    Ability to quantify dissimilarity of different phylogenetic trees describing the relationship between the same group of taxa is required in various types of phylogenetic studies. For example, such metrics are used to assess the quality of phylogeny construction methods, to define optimization criteria in supertree building algorithms, or to find horizontal gene transfer (HGT) events. Among the set of metrics described so far in the literature, the most commonly used seems to be the Robinson-Foulds distance. In this article, we define a new metric for rooted trees-the Matching Pair (MP) distance. The MP metric uses the concept of the minimum-weight perfect matching in a complete bipartite graph constructed from partitions of all pairs of leaves of the compared phylogenetic trees. We analyze the properties of the MP metric and present computational experiments showing its potential applicability in tasks related to finding the HGT events.

  10. 20 CFR 625.1 - Purpose; rules of construction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... UNEMPLOYMENT ASSISTANCE § 625.1 Purpose; rules of construction. (a) Purpose. Section 410 of “The Robert T. Stafford Disaster Relief and Emergency Assistance Act” amended the program for the payment of unemployment assistance to unemployed individuals whose unemployment is caused by a major disaster, and to provide...

  11. 20 CFR 625.1 - Purpose; rules of construction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... UNEMPLOYMENT ASSISTANCE § 625.1 Purpose; rules of construction. (a) Purpose. Section 410 of “The Robert T. Stafford Disaster Relief and Emergency Assistance Act” amended the program for the payment of unemployment assistance to unemployed individuals whose unemployment is caused by a major disaster, and to provide...

  12. 20 CFR 625.1 - Purpose; rules of construction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... UNEMPLOYMENT ASSISTANCE § 625.1 Purpose; rules of construction. (a) Purpose. Section 410 of “The Robert T. Stafford Disaster Relief and Emergency Assistance Act” amended the program for the payment of unemployment assistance to unemployed individuals whose unemployment is caused by a major disaster, and to provide...

  13. 20 CFR 625.1 - Purpose; rules of construction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... UNEMPLOYMENT ASSISTANCE § 625.1 Purpose; rules of construction. (a) Purpose. Section 410 of “The Robert T. Stafford Disaster Relief and Emergency Assistance Act” amended the program for the payment of unemployment assistance to unemployed individuals whose unemployment is caused by a major disaster, and to provide...

  14. Genomic taxonomy of vibrios

    PubMed Central

    Thompson, Cristiane C; Vicente, Ana Carolina P; Souza, Rangel C; Vasconcelos, Ana Tereza R; Vesth, Tammi; Alves, Nelson; Ussery, David W; Iida, Tetsuya; Thompson, Fabiano L

    2009-01-01

    Background Vibrio taxonomy has been based on a polyphasic approach. In this study, we retrieve useful taxonomic information (i.e. data that can be used to distinguish different taxonomic levels, such as species and genera) from 32 genome sequences of different vibrio species. We use a variety of tools to explore the taxonomic relationship between the sequenced genomes, including Multilocus Sequence Analysis (MLSA), supertrees, Average Amino Acid Identity (AAI), genomic signatures, and Genome BLAST atlases. Our aim is to analyse the usefulness of these tools for species identification in vibrios. Results We have generated four new genome sequences of three Vibrio species, i.e., V. alginolyticus 40B, V. harveyi-like 1DA3, and V. mimicus strains VM573 and VM603, and present a broad analyses of these genomes along with other sequenced Vibrio species. The genome atlas and pangenome plots provide a tantalizing image of the genomic differences that occur between closely related sister species, e.g. V. cholerae and V. mimicus. The vibrio pangenome contains around 26504 genes. The V. cholerae core genome and pangenome consist of 1520 and 6923 genes, respectively. Pangenomes might allow different strains of V. cholerae to occupy different niches. MLSA and supertree analyses resulted in a similar phylogenetic picture, with a clear distinction of four groups (Vibrio core group, V. cholerae-V. mimicus, Aliivibrio spp., and Photobacterium spp.). A Vibrio species is defined as a group of strains that share > 95% DNA identity in MLSA and supertree analysis, > 96% AAI, ≤ 10 genome signature dissimilarity, and > 61% proteome identity. Strains of the same species and species of the same genus will form monophyletic groups on the basis of MLSA and supertree. Conclusion The combination of different analytical and bioinformatics tools will enable the most accurate species identification through genomic computational analysis. This endeavour will culminate in the birth of the online genomic taxonomy whereby researchers and end-users of taxonomy will be able to identify their isolates through a web-based server. This novel approach to microbial systematics will result in a tremendous advance concerning biodiversity discovery, description, and understanding. PMID:19860885

  15. Phylogenomic Reconstruction of the Oomycete Phylogeny Derived from 37 Genomes

    PubMed Central

    McCarthy, Charley G. P.

    2017-01-01

    ABSTRACT The oomycetes are a class of microscopic, filamentous eukaryotes within the Stramenopiles-Alveolata-Rhizaria (SAR) supergroup which includes ecologically significant animal and plant pathogens, most infamously the causative agent of potato blight Phytophthora infestans. Single-gene and concatenated phylogenetic studies both of individual oomycete genera and of members of the larger class have resulted in conflicting conclusions concerning species phylogenies within the oomycetes, particularly for the large Phytophthora genus. Genome-scale phylogenetic studies have successfully resolved many eukaryotic relationships by using supertree methods, which combine large numbers of potentially disparate trees to determine evolutionary relationships that cannot be inferred from individual phylogenies alone. With a sufficient amount of genomic data now available, we have undertaken the first whole-genome phylogenetic analysis of the oomycetes using data from 37 oomycete species and 6 SAR species. In our analysis, we used established supertree methods to generate phylogenies from 8,355 homologous oomycete and SAR gene families and have complemented those analyses with both phylogenomic network and concatenated supermatrix analyses. Our results show that a genome-scale approach to oomycete phylogeny resolves oomycete classes and individual clades within the problematic Phytophthora genus. Support for the resolution of the inferred relationships between individual Phytophthora clades varies depending on the methodology used. Our analysis represents an important first step in large-scale phylogenomic analysis of the oomycetes. IMPORTANCE The oomycetes are a class of eukaryotes and include ecologically significant animal and plant pathogens. Single-gene and multigene phylogenetic studies of individual oomycete genera and of members of the larger classes have resulted in conflicting conclusions concerning interspecies relationships among these species, particularly for the Phytophthora genus. The onset of next-generation sequencing techniques now means that a wealth of oomycete genomic data is available. For the first time, we have used genome-scale phylogenetic methods to resolve oomycete phylogenetic relationships. We used supertree methods to generate single-gene and multigene species phylogenies. Overall, our supertree analyses utilized phylogenetic data from 8,355 oomycete gene families. We have also complemented our analyses with superalignment phylogenies derived from 131 single-copy ubiquitous gene families. Our results show that a genome-scale approach to oomycete phylogeny resolves oomycete classes and clades. Our analysis represents an important first step in large-scale phylogenomic analysis of the oomycetes. PMID:28435885

  16. 75 FR 60263 - Federal Acquisition Regulation; Offering a Construction Requirement-8(a) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... geographical area where the work is to be performed. However, the SBA regulation requires the offering letters... September 30, 1993. This rule is not a major rule under 5 U.S.C. 804. B. Regulatory Flexibility Act The Regulatory Flexibility Act does not apply to this rule. This final rule does not constitute a significant FAR...

  17. Unfair "Housing Regulation of Major Construction" in the Russian Federation

    ERIC Educational Resources Information Center

    Goncharov, Alexander I.; Inshakova, Agnessa O.; Kazachenok, Olesya P.; Dikarev, Ilya S.

    2016-01-01

    This research analyzes the illegal and unreasonable practice of court rulings that aim to accelerate the major construction of problematic long-delayed apartment blocks in the Russian Federation. The authors express their critical attitude to the widespread wrongful approach that violates the laws in effect and allows courts to apply…

  18. A Bayesian Supertree Model for Genome-Wide Species Tree Reconstruction

    PubMed Central

    De Oliveira Martins, Leonardo; Mallo, Diego; Posada, David

    2016-01-01

    Current phylogenomic data sets highlight the need for species tree methods able to deal with several sources of gene tree/species tree incongruence. At the same time, we need to make most use of all available data. Most species tree methods deal with single processes of phylogenetic discordance, namely, gene duplication and loss, incomplete lineage sorting (ILS) or horizontal gene transfer. In this manuscript, we address the problem of species tree inference from multilocus, genome-wide data sets regardless of the presence of gene duplication and loss and ILS therefore without the need to identify orthologs or to use a single individual per species. We do this by extending the idea of Maximum Likelihood (ML) supertrees to a hierarchical Bayesian model where several sources of gene tree/species tree disagreement can be accounted for in a modular manner. We implemented this model in a computer program called guenomu whose inputs are posterior distributions of unrooted gene tree topologies for multiple gene families, and whose output is the posterior distribution of rooted species tree topologies. We conducted extensive simulations to evaluate the performance of our approach in comparison with other species tree approaches able to deal with more than one leaf from the same species. Our method ranked best under simulated data sets, in spite of ignoring branch lengths, and performed well on empirical data, as well as being fast enough to analyze relatively large data sets. Our Bayesian supertree method was also very successful in obtaining better estimates of gene trees, by reducing the uncertainty in their distributions. In addition, our results show that under complex simulation scenarios, gene tree parsimony is also a competitive approach once we consider its speed, in contrast to more sophisticated models. PMID:25281847

  19. 19 CFR 351.407 - Calculation of constructed value and cost of production.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... production. (See section 773(f) of the Act.) (b) Determination of value under the major input rule. For purposes of section 773(f)(3) of the Act, the Secretary normally will determine the value of a major input... to the affiliated person for the major input; (2) The amount usually reflected in sales of the major...

  20. 19 CFR 351.407 - Calculation of constructed value and cost of production.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... production. (See section 773(f) of the Act.) (b) Determination of value under the major input rule. For purposes of section 773(f)(3) of the Act, the Secretary normally will determine the value of a major input... to the affiliated person for the major input; (2) The amount usually reflected in sales of the major...

  1. 19 CFR 351.407 - Calculation of constructed value and cost of production.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... production. (See section 773(f) of the Act.) (b) Determination of value under the major input rule. For purposes of section 773(f)(3) of the Act, the Secretary normally will determine the value of a major input... to the affiliated person for the major input; (2) The amount usually reflected in sales of the major...

  2. 19 CFR 351.407 - Calculation of constructed value and cost of production.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... production. (See section 773(f) of the Act.) (b) Determination of value under the major input rule. For purposes of section 773(f)(3) of the Act, the Secretary normally will determine the value of a major input... to the affiliated person for the major input; (2) The amount usually reflected in sales of the major...

  3. 19 CFR 351.407 - Calculation of constructed value and cost of production.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... production. (See section 773(f) of the Act.) (b) Determination of value under the major input rule. For purposes of section 773(f)(3) of the Act, the Secretary normally will determine the value of a major input... to the affiliated person for the major input; (2) The amount usually reflected in sales of the major...

  4. Demographic Variables of Corruption in the Chinese Construction Industry: Association Rule Analysis of Conviction Records.

    PubMed

    Yu, Yao; Martek, Igor; Hosseini, M Reza; Chen, Chuan

    2018-05-02

    Corruption in the construction industry is a serious problem in China. As such, fighting this corruption has become a priority target of the Chinese government, with the main effort being to discover and prosecute its perpetrators. This study profiles the demographic characteristics of major incidences of corruption in construction. It draws on the database of the 83 complete recorded cases of construction related corruption held by the Chinese National Bureau of Corruption Prevention. Categorical variables were drawn from the database, and 'association rule mining analysis' was used to identify associations between variables as a means of profiling perpetrators. Such profiling may be used as predictors of future incidences of corruption, and consequently to inform policy makers in their fight against corruption. The results signal corruption within the Chinese construction industry to be correlated with age, with incidences rising as managers' approach retirement age. Moreover, a majority of perpetrators operate within government agencies, are department deputies in direct contact with projects, and extort the greatest amounts per case from second tier cities. The relatively lengthy average 6.4-year period before cases come to public attention corroborates the view that current efforts at fighting corruption remain inadequate.

  5. A hybrid learning method for constructing compact rule-based fuzzy models.

    PubMed

    Zhao, Wanqing; Niu, Qun; Li, Kang; Irwin, George W

    2013-12-01

    The Takagi–Sugeno–Kang-type rule-based fuzzy model has found many applications in different fields; a major challenge is, however, to build a compact model with optimized model parameters which leads to satisfactory model performance. To produce a compact model, most existing approaches mainly focus on selecting an appropriate number of fuzzy rules. In contrast, this paper considers not only the selection of fuzzy rules but also the structure of each rule premise and consequent, leading to the development of a novel compact rule-based fuzzy model. Here, each fuzzy rule is associated with two sets of input attributes, in which the first is used for constructing the rule premise and the other is employed in the rule consequent. A new hybrid learning method combining the modified harmony search method with a fast recursive algorithm is hereby proposed to determine the structure and the parameters for the rule premises and consequents. This is a hard mixed-integer nonlinear optimization problem, and the proposed hybrid method solves the problem by employing an embedded framework, leading to a significantly reduced number of model parameters and a small number of fuzzy rules with each being as simple as possible. Results from three examples are presented to demonstrate the compactness (in terms of the number of model parameters and the number of rules) and the performance of the fuzzy models obtained by the proposed hybrid learning method, in comparison with other techniques from the literature.

  6. 18 CFR 385.104 - Rule of construction (Rule 104).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Rule of construction (Rule 104). 385.104 Section 385.104 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Definitions § 385.104 Rule of construction (Rule 104). To the extent that the text of a rule is inconsistent...

  7. 18 CFR 385.104 - Rule of construction (Rule 104).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Rule of construction (Rule 104). 385.104 Section 385.104 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Definitions § 385.104 Rule of construction (Rule 104). To the extent that the text of a rule is inconsistent...

  8. Measuring uncertainty by extracting fuzzy rules using rough sets

    NASA Technical Reports Server (NTRS)

    Worm, Jeffrey A.

    1991-01-01

    Despite the advancements in the computer industry in the past 30 years, there is still one major deficiency. Computers are not designed to handle terms where uncertainty is present. To deal with uncertainty, techniques other than classical logic must be developed. The methods are examined of statistical analysis, the Dempster-Shafer theory, rough set theory, and fuzzy set theory to solve this problem. The fundamentals of these theories are combined to possibly provide the optimal solution. By incorporating principles from these theories, a decision making process may be simulated by extracting two sets of fuzzy rules: certain rules and possible rules. From these rules a corresponding measure of how much these rules is believed is constructed. From this, the idea of how much a fuzzy diagnosis is definable in terms of a set of fuzzy attributes is studied.

  9. Polynomial-Time Algorithms for Building a Consensus MUL-Tree

    PubMed Central

    Cui, Yun; Jansson, Jesper

    2012-01-01

    Abstract A multi-labeled phylogenetic tree, or MUL-tree, is a generalization of a phylogenetic tree that allows each leaf label to be used many times. MUL-trees have applications in biogeography, the study of host–parasite cospeciation, gene evolution studies, and computer science. Here, we consider the problem of inferring a consensus MUL-tree that summarizes a given set of conflicting MUL-trees, and present the first polynomial-time algorithms for solving it. In particular, we give a straightforward, fast algorithm for building a strict consensus MUL-tree for any input set of MUL-trees with identical leaf label multisets, as well as a polynomial-time algorithm for building a majority rule consensus MUL-tree for the special case where every leaf label occurs at most twice. We also show that, although it is NP-hard to find a majority rule consensus MUL-tree in general, the variant that we call the singular majority rule consensus MUL-tree can be constructed efficiently whenever it exists. PMID:22963134

  10. Polynomial-time algorithms for building a consensus MUL-tree.

    PubMed

    Cui, Yun; Jansson, Jesper; Sung, Wing-Kin

    2012-09-01

    A multi-labeled phylogenetic tree, or MUL-tree, is a generalization of a phylogenetic tree that allows each leaf label to be used many times. MUL-trees have applications in biogeography, the study of host-parasite cospeciation, gene evolution studies, and computer science. Here, we consider the problem of inferring a consensus MUL-tree that summarizes a given set of conflicting MUL-trees, and present the first polynomial-time algorithms for solving it. In particular, we give a straightforward, fast algorithm for building a strict consensus MUL-tree for any input set of MUL-trees with identical leaf label multisets, as well as a polynomial-time algorithm for building a majority rule consensus MUL-tree for the special case where every leaf label occurs at most twice. We also show that, although it is NP-hard to find a majority rule consensus MUL-tree in general, the variant that we call the singular majority rule consensus MUL-tree can be constructed efficiently whenever it exists.

  11. Ancient origins and multiple appearances of carotenoid-pigmented feathers in birds

    PubMed Central

    Thomas, Daniel B.; McGraw, Kevin J.; Butler, Michael W.; Carrano, Matthew T.; Madden, Odile; James, Helen F.

    2014-01-01

    The broad palette of feather colours displayed by birds serves diverse biological functions, including communication and camouflage. Fossil feathers provide evidence that some avian colours, like black and brown melanins, have existed for at least 160 million years (Myr), but no traces of bright carotenoid pigments in ancient feathers have been reported. Insight into the evolutionary history of plumage carotenoids may instead be gained from living species. We visually surveyed modern birds for carotenoid-consistent plumage colours (present in 2956 of 9993 species). We then used high-performance liquid chromatography and Raman spectroscopy to chemically assess the family-level distribution of plumage carotenoids, confirming their presence in 95 of 236 extant bird families (only 36 family-level occurrences had been confirmed previously). Using our data for all modern birds, we modelled the evolutionary history of carotenoid-consistent plumage colours on recent supertrees. Results support multiple independent origins of carotenoid plumage pigmentation in 13 orders, including six orders without previous reports of plumage carotenoids. Based on time calibrations from the supertree, the number of avian families displaying plumage carotenoids increased throughout the Cenozoic, and most plumage carotenoid originations occurred after the Miocene Epoch (23 Myr). The earliest origination of plumage carotenoids was reconstructed within Passeriformes, during the Palaeocene Epoch (66–56 Myr), and not at the base of crown-lineage birds. PMID:24966316

  12. Exact solutions for species tree inference from discordant gene trees.

    PubMed

    Chang, Wen-Chieh; Górecki, Paweł; Eulenstein, Oliver

    2013-10-01

    Phylogenetic analysis has to overcome the grant challenge of inferring accurate species trees from evolutionary histories of gene families (gene trees) that are discordant with the species tree along whose branches they have evolved. Two well studied approaches to cope with this challenge are to solve either biologically informed gene tree parsimony (GTP) problems under gene duplication, gene loss, and deep coalescence, or the classic RF supertree problem that does not rely on any biological model. Despite the potential of these problems to infer credible species trees, they are NP-hard. Therefore, these problems are addressed by heuristics that typically lack any provable accuracy and precision. We describe fast dynamic programming algorithms that solve the GTP problems and the RF supertree problem exactly, and demonstrate that our algorithms can solve instances with data sets consisting of as many as 22 taxa. Extensions of our algorithms can also report the number of all optimal species trees, as well as the trees themselves. To better asses the quality of the resulting species trees that best fit the given gene trees, we also compute the worst case species trees, their numbers, and optimization score for each of the computational problems. Finally, we demonstrate the performance of our exact algorithms using empirical and simulated data sets, and analyze the quality of heuristic solutions for the studied problems by contrasting them with our exact solutions.

  13. 29 CFR 2700.1 - Scope; applicability of other rules; construction.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... work injustice, in which event the former rules of procedure would continue to apply. (b) Applicability... 29 Labor 9 2010-07-01 2010-07-01 false Scope; applicability of other rules; construction. 2700.1... COMMISSION PROCEDURAL RULES General Provisions § 2700.1 Scope; applicability of other rules; construction. (a...

  14. 14 CFR 151.77 - Runway paving: General rules.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... project include pavement construction and reconstruction, and include runway grooving to improve skid... course to correct major irregularities in the pavement. Runway resealing or refilling joints as an... Specification P-609) on a pavement the current surface of which consists of that kind of a bituminous surface...

  15. 14 CFR 151.77 - Runway paving: General rules.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... project include pavement construction and reconstruction, and include runway grooving to improve skid... course to correct major irregularities in the pavement. Runway resealing or refilling joints as an... Specification P-609) on a pavement the current surface of which consists of that kind of a bituminous surface...

  16. 14 CFR 151.77 - Runway paving: General rules.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... project include pavement construction and reconstruction, and include runway grooving to improve skid... course to correct major irregularities in the pavement. Runway resealing or refilling joints as an... Specification P-609) on a pavement the current surface of which consists of that kind of a bituminous surface...

  17. 14 CFR 151.77 - Runway paving: General rules.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... project include pavement construction and reconstruction, and include runway grooving to improve skid... course to correct major irregularities in the pavement. Runway resealing or refilling joints as an... Specification P-609) on a pavement the current surface of which consists of that kind of a bituminous surface...

  18. 14 CFR 151.77 - Runway paving: General rules.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... project include pavement construction and reconstruction, and include runway grooving to improve skid... course to correct major irregularities in the pavement. Runway resealing or refilling joints as an... Specification P-609) on a pavement the current surface of which consists of that kind of a bituminous surface...

  19. 29 CFR 2200.2 - Scope of rules; applicability of Federal Rules of Civil Procedure; construction.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; applicability of Federal Rules of Civil Procedure; construction. (a) Scope. These rules shall govern all proceedings before the Commission and its Judges. (b) Applicability of Federal Rules of Civil Procedure. In the absence of a specific provision, procedure shall be in accordance with the Federal Rules of Civil...

  20. 29 CFR 2200.2 - Scope of rules; applicability of Federal Rules of Civil Procedure; construction.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...; applicability of Federal Rules of Civil Procedure; construction. (a) Scope. These rules shall govern all proceedings before the Commission and its Judges. (b) Applicability of Federal Rules of Civil Procedure. In the absence of a specific provision, procedure shall be in accordance with the Federal Rules of Civil...

  1. The Moral Construction of the Good Pupil Embedded in School Rules

    ERIC Educational Resources Information Center

    Thornberg, Robert

    2009-01-01

    The aim of this field study was to investigate the hidden curriculum of school rules delimited to the moral construction of "the good pupil" embedded in the system of school rules in two primary schools. According to the findings, the rule system mediates a moral construction of the good pupil to the children, and this actually includes…

  2. 26 CFR 48.4216(b)-2 - Constructive sale price; basic rules.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 16 2010-04-01 2010-04-01 true Constructive sale price; basic rules. 48.4216(b... to Manufacturers Taxes § 48.4216(b)-2 Constructive sale price; basic rules. (a) In general. Section 4216(b)(1) sets forth the conditions that require the Secretary to construct a sale price on which to...

  3. 29 CFR 4211.3 - Special rules for construction industry and IRC section 404(c) plans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 9 2014-07-01 2014-07-01 false Special rules for construction industry and IRC section 404... WITHDRAWING EMPLOYERS General § 4211.3 Special rules for construction industry and IRC section 404(c) plans... covers employees in the building and construction industry shall use the presumptive method for...

  4. 29 CFR 4211.3 - Special rules for construction industry and IRC section 404(c) plans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 9 2013-07-01 2013-07-01 false Special rules for construction industry and IRC section 404... WITHDRAWING EMPLOYERS General § 4211.3 Special rules for construction industry and IRC section 404(c) plans... covers employees in the building and construction industry shall use the presumptive method for...

  5. 29 CFR 4211.3 - Special rules for construction industry and IRC section 404(c) plans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 9 2012-07-01 2012-07-01 false Special rules for construction industry and IRC section 404... WITHDRAWING EMPLOYERS General § 4211.3 Special rules for construction industry and IRC section 404(c) plans... covers employees in the building and construction industry shall use the presumptive method for...

  6. 29 CFR 4211.3 - Special rules for construction industry and IRC section 404(c) plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Special rules for construction industry and IRC section 404... WITHDRAWING EMPLOYERS General § 4211.3 Special rules for construction industry and IRC section 404(c) plans... covers employees in the building and construction industry shall use the presumptive method for...

  7. 29 CFR 4211.3 - Special rules for construction industry and IRC section 404(c) plans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 9 2011-07-01 2011-07-01 false Special rules for construction industry and IRC section 404... WITHDRAWING EMPLOYERS General § 4211.3 Special rules for construction industry and IRC section 404(c) plans... covers employees in the building and construction industry shall use the presumptive method for...

  8. Hotspots and the conservation of evolutionary history

    PubMed Central

    Sechrest, Wes; Brooks, Thomas M.; da Fonseca, Gustavo A. B.; Konstant, William R.; Mittermeier, Russell A.; Purvis, Andy; Rylands, Anthony B.; Gittleman, John L.

    2002-01-01

    Species diversity is unevenly distributed across the globe, with terrestrial diversity concentrated in a few restricted biodiversity hotspots. These areas are associated with high losses of primary vegetation and increased human population density, resulting in growing numbers of threatened species. We show that conservation of these hotspots is critical because they harbor even greater amounts of evolutionary history than expected by species numbers alone. We used supertrees for carnivores and primates to estimate that nearly 70% of the total amount of evolutionary history represented in these groups is found in 25 biodiversity hotspots. PMID:11854502

  9. 38 CFR 20.1 - Rule 1. Purpose and construction of Rules of Practice.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Rule 1. Purpose and construction of Rules of Practice. 20.1 Section 20.1 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) BOARD OF VETERANS' APPEALS: RULES OF PRACTICE General § 20.1 Rule 1. Purpose...

  10. 38 CFR 20.1 - Rule 1. Purpose and construction of Rules of Practice.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Rule 1. Purpose and construction of Rules of Practice. 20.1 Section 20.1 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) BOARD OF VETERANS' APPEALS: RULES OF PRACTICE General § 20.1 Rule 1. Purpose...

  11. 77 FR 38351 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... mines to upgraded copper products--is highly dependent on global trade. According to CPM Group, a... roughly 55% of global output in 2011, while roughly 46% production is performed in Asia. BILLING CODE 8011... global industrial activity, given copper's prominence in major economic sectors such as construction...

  12. 77 FR 65305 - Approval of Air Quality Implementation Plans; California; San Joaquin Valley Unified Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... incorporates District Rule 2410-- Prevention of Significant Deterioration (PSD)--into the California SIP to establish a PSD permit program for pre-construction review of certain new and modified major stationary... provides an adequate PSD permitting program as required by section 110 and part C of title I of the CAA...

  13. 14 CFR 1.3 - Rules of construction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Rules of construction. 1.3 Section 1.3 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION DEFINITIONS DEFINITIONS AND ABBREVIATIONS § 1.3 Rules of construction. (a) In subchapters A through K of this chapter, unless...

  14. 49 CFR 1101.3 - Construction.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 8 2012-10-01 2012-10-01 false Construction. 1101.3 Section 1101.3 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE DEFINITIONS AND CONSTRUCTION § 1101.3 Construction. The rules of construction...

  15. 49 CFR 1101.3 - Construction.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 8 2014-10-01 2014-10-01 false Construction. 1101.3 Section 1101.3 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE DEFINITIONS AND CONSTRUCTION § 1101.3 Construction. The rules of construction...

  16. 49 CFR 1101.3 - Construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 8 2011-10-01 2011-10-01 false Construction. 1101.3 Section 1101.3 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE DEFINITIONS AND CONSTRUCTION § 1101.3 Construction. The rules of construction...

  17. 49 CFR 1101.3 - Construction.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 8 2013-10-01 2013-10-01 false Construction. 1101.3 Section 1101.3 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE DEFINITIONS AND CONSTRUCTION § 1101.3 Construction. The rules of construction...

  18. 49 CFR 1101.3 - Construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Construction. 1101.3 Section 1101.3 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE DEFINITIONS AND CONSTRUCTION § 1101.3 Construction. The rules of construction...

  19. Belief Function Based Decision Fusion for Decentralized Target Classification in Wireless Sensor Networks

    PubMed Central

    Zhang, Wenyu; Zhang, Zhenjiang

    2015-01-01

    Decision fusion in sensor networks enables sensors to improve classification accuracy while reducing the energy consumption and bandwidth demand for data transmission. In this paper, we focus on the decentralized multi-class classification fusion problem in wireless sensor networks (WSNs) and a new simple but effective decision fusion rule based on belief function theory is proposed. Unlike existing belief function based decision fusion schemes, the proposed approach is compatible with any type of classifier because the basic belief assignments (BBAs) of each sensor are constructed on the basis of the classifier’s training output confusion matrix and real-time observations. We also derive explicit global BBA in the fusion center under Dempster’s combinational rule, making the decision making operation in the fusion center greatly simplified. Also, sending the whole BBA structure to the fusion center is avoided. Experimental results demonstrate that the proposed fusion rule has better performance in fusion accuracy compared with the naïve Bayes rule and weighted majority voting rule. PMID:26295399

  20. One tree to link them all: a phylogenetic dataset for the European tetrapoda.

    PubMed

    Roquet, Cristina; Lavergne, Sébastien; Thuiller, Wilfried

    2014-08-08

    Since the ever-increasing availability of phylogenetic informative data, the last decade has seen an upsurge of ecological studies incorporating information on evolutionary relationships among species. However, detailed species-level phylogenies are still lacking for many large groups and regions, which are necessary for comprehensive large-scale eco-phylogenetic analyses. Here, we provide a dataset of 100 dated phylogenetic trees for all European tetrapods based on a mixture of supermatrix and supertree approaches. Phylogenetic inference was performed separately for each of the main Tetrapoda groups of Europe except mammals (i.e. amphibians, birds, squamates and turtles) by means of maximum likelihood (ML) analyses of supermatrix applying a tree constraint at the family (amphibians and squamates) or order (birds and turtles) levels based on consensus knowledge. For each group, we inferred 100 ML trees to be able to provide a phylogenetic dataset that accounts for phylogenetic uncertainty, and assessed node support with bootstrap analyses. Each tree was dated using penalized-likelihood and fossil calibration. The trees obtained were well-supported by existing knowledge and previous phylogenetic studies. For mammals, we modified the most complete supertree dataset available on the literature to include a recent update of the Carnivora clade. As a final step, we merged the phylogenetic trees of all groups to obtain a set of 100 phylogenetic trees for all European Tetrapoda species for which data was available (91%). We provide this phylogenetic dataset (100 chronograms) for the purpose of comparative analyses, macro-ecological or community ecology studies aiming to incorporate phylogenetic information while accounting for phylogenetic uncertainty.

  1. 31 CFR 50.6 - Rule of construction for dates.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Rule of construction for dates. 50.6 Section 50.6 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM General Provisions § 50.6 Rule of construction for dates. Unless otherwise expressly provided in...

  2. 31 CFR 50.6 - Rule of construction for dates.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Rule of construction for dates. 50.6 Section 50.6 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM General Provisions § 50.6 Rule of construction for dates. Unless otherwise expressly provided in...

  3. 31 CFR 50.6 - Rule of construction for dates.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Rule of construction for dates. 50.6 Section 50.6 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM General Provisions § 50.6 Rule of construction for dates. Unless otherwise expressly provided in...

  4. 31 CFR 50.6 - Rule of construction for dates.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Rule of construction for dates. 50.6 Section 50.6 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM General Provisions § 50.6 Rule of construction for dates. Unless otherwise expressly provided in...

  5. 12 CFR 308.12 - Construction of time limits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Construction of time limits. 308.12 Section 308.12 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF PRACTICE AND PROCEDURE Uniform Rules of Practice and Procedure § 308.12 Construction of time limits. (a...

  6. 12 CFR 19.12 - Construction of time limits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Construction of time limits. 19.12 Section 19.12 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY RULES OF PRACTICE AND PROCEDURE Uniform Rules of Practice and Procedure § 19.12 Construction of time limits. (a) General rule. In...

  7. 7 CFR 1780.3 - Definitions and grammatical rules of construction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Definitions and grammatical rules of construction... and Requirements § 1780.3 Definitions and grammatical rules of construction. (a) Definitions. For the... level of income for a family of four, as defined in section 673(2) of the Community Services Block Grant...

  8. 78 FR 23837 - Cranes and Derricks in Construction: Underground Construction and Demolition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... report here the results for the entire heavy-and-civil engineering sector and the entire site... in this final rule because employers included in the heavy-and-civil engineering sector, or the site... final rule. This final rule affects two construction sectors: NAICS 237990 (Other Heavy and Civil...

  9. 31 CFR 50.6 - Rule of construction for dates.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Rule of construction for dates. 50.6 Section 50.6 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM General Provisions § 50.6 Rule of construction for dates. Unless otherwise expressly provided in...

  10. 26 CFR 48.4216(b)-3 - Constructive sale price; special rule for arm's-length sales.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 16 2011-04-01 2011-04-01 false Constructive sale price; special rule for arm's... Provisions Applicable to Manufacturers Taxes § 48.4216(b)-3 Constructive sale price; special rule for arm's... such articles to one or more wholesale distributors in arm's-length transactions, and the manufacturer...

  11. 26 CFR 48.4216(b)-3 - Constructive sale price; special rule for arm's-length sales.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 16 2013-04-01 2013-04-01 false Constructive sale price; special rule for arm's... Provisions Applicable to Manufacturers Taxes § 48.4216(b)-3 Constructive sale price; special rule for arm's... such articles to one or more wholesale distributors in arm's-length transactions, and the manufacturer...

  12. 26 CFR 48.4216(b)-3 - Constructive sale price; special rule for arm's-length sales.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 16 2012-04-01 2012-04-01 false Constructive sale price; special rule for arm's... Provisions Applicable to Manufacturers Taxes § 48.4216(b)-3 Constructive sale price; special rule for arm's... such articles to one or more wholesale distributors in arm's-length transactions, and the manufacturer...

  13. A broad-scale comparison of aerobic activity levels in vertebrates: endotherms versus ectotherms

    PubMed Central

    Gomez, Juan Pablo; Mavrodiev, Evgeny V.

    2017-01-01

    Differences in the limits and range of aerobic activity levels between endotherms and ectotherms remain poorly understood, though such differences help explain basic differences in species' lifestyles (e.g. movement patterns, feeding modes, and interaction rates). We compare the limits and range of aerobic activity in endotherms (birds and mammals) and ectotherms (fishes, reptiles, and amphibians) by evaluating the body mass-dependence of VO2 max, aerobic scope, and heart mass in a phylogenetic context based on a newly constructed vertebrate supertree. Contrary to previous work, results show no significant differences in the body mass scaling of minimum and maximum oxygen consumption rates with body mass within endotherms or ectotherms. For a given body mass, resting rates and maximum rates were 24-fold and 30-fold lower, respectively, in ectotherms than endotherms. Factorial aerobic scope ranged from five to eight in both groups, with scope in endotherms showing a modest body mass-dependence. Finally, maximum consumption rates and aerobic scope were positively correlated with residual heart mass. Together, these results quantify similarities and differences in the potential for aerobic activity among ectotherms and endotherms from diverse environments. They provide insights into the models and mechanisms that may underlie the body mass-dependence of oxygen consumption. PMID:28202808

  14. 75 FR 68215 - Direct Final Rule Staying Numeric Limitation for the Construction and Development Point Source...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-05

    ... required to obtain NPDES permit coverage and performing the following activities: Construction of buildings, including building, developing and general contracting. Heavy and civil 237 engineering construction... Rule Staying Numeric Limitation for the Construction and Development Point Source Category AGENCY...

  15. The Evolution of Haploid Chromosome Numbers in the Sunflower Family

    PubMed Central

    Mota, Lucie; Torices, Rubén; Loureiro, João

    2016-01-01

    Chromosome number changes during the evolution of angiosperms are likely to have played a major role in speciation. Their study is of utmost importance, especially now, as a probabilistic model is available to study chromosome evolution within a phylogenetic framework. In the present study, likelihood models of chromosome number evolution were fitted to the largest family of flowering plants, the Asteraceae. Specifically, a phylogenetic supertree of this family was used to reconstruct the ancestral chromosome number and infer genomic events. Our approach inferred that the ancestral chromosome number of the family is n = 9. Also, according to the model that best explained our data, the evolution of haploid chromosome numbers in Asteraceae was a very dynamic process, with genome duplications and descending dysploidy being the most frequent genomic events in the evolution of this family. This model inferred more than one hundred whole genome duplication events; however, it did not find evidence for a paleopolyploidization at the base of this family, which has previously been hypothesized on the basis of sequence data from a limited number of species. The obtained results and potential causes of these discrepancies are discussed. PMID:27797951

  16. A novel prosodic-information synthesizer based on recurrent fuzzy neural network for the Chinese TTS system.

    PubMed

    Lin, Chin-Teng; Wu, Rui-Cheng; Chang, Jyh-Yeong; Liang, Sheng-Fu

    2004-02-01

    In this paper, a new technique for the Chinese text-to-speech (TTS) system is proposed. Our major effort focuses on the prosodic information generation. New methodologies for constructing fuzzy rules in a prosodic model simulating human's pronouncing rules are developed. The proposed Recurrent Fuzzy Neural Network (RFNN) is a multilayer recurrent neural network (RNN) which integrates a Self-cOnstructing Neural Fuzzy Inference Network (SONFIN) into a recurrent connectionist structure. The RFNN can be functionally divided into two parts. The first part adopts the SONFIN as a prosodic model to explore the relationship between high-level linguistic features and prosodic information based on fuzzy inference rules. As compared to conventional neural networks, the SONFIN can always construct itself with an economic network size in high learning speed. The second part employs a five-layer network to generate all prosodic parameters by directly using the prosodic fuzzy rules inferred from the first part as well as other important features of syllables. The TTS system combined with the proposed method can behave not only sandhi rules but also the other prosodic phenomena existing in the traditional TTS systems. Moreover, the proposed scheme can even find out some new rules about prosodic phrase structure. The performance of the proposed RFNN-based prosodic model is verified by imbedding it into a Chinese TTS system with a Chinese monosyllable database based on the time-domain pitch synchronous overlap add (TD-PSOLA) method. Our experimental results show that the proposed RFNN can generate proper prosodic parameters including pitch means, pitch shapes, maximum energy levels, syllable duration, and pause duration. Some synthetic sounds are online available for demonstration.

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pin, F.G.

    Sensor-based operation of autonomous robots in unstructured and/or outdoor environments has revealed to be an extremely challenging problem, mainly because of the difficulties encountered when attempting to represent the many uncertainties which are always present in the real world. These uncertainties are primarily due to sensor imprecisions and unpredictability of the environment, i.e., lack of full knowledge of the environment characteristics and dynamics. An approach. which we have named the {open_quotes}Fuzzy Behaviorist Approach{close_quotes} (FBA) is proposed in an attempt to remedy some of these difficulties. This approach is based on the representation of the system`s uncertainties using Fuzzy Set Theory-basedmore » approximations and on the representation of the reasoning and control schemes as sets of elemental behaviors. Using the FBA, a formalism for rule base development and an automated generator of fuzzy rules have been developed. This automated system can automatically construct the set of membership functions corresponding to fuzzy behaviors. Once these have been expressed in qualitative terms by the user. The system also checks for completeness of the rule base and for non-redundancy of the rules (which has traditionally been a major hurdle in rule base development). Two major conceptual features, the suppression and inhibition mechanisms which allow to express a dominance between behaviors are discussed in detail. Some experimental results obtained with the automated fuzzy, rule generator applied to the domain of sensor-based navigation in aprion unknown environments. using one of our autonomous test-bed robots as well as a real car in outdoor environments, are then reviewed and discussed to illustrate the feasibility of large-scale automatic fuzzy rule generation using the {open_quotes}Fuzzy Behaviorist{close_quotes} concepts.« less

  18. 49 CFR 1100.3 - Liberal construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 8 2011-10-01 2011-10-01 false Liberal construction. 1100.3 Section 1100.3 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE GENERAL PROVISIONS § 1100.3 Liberal construction. The rules will...

  19. 49 CFR 1100.3 - Liberal construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Liberal construction. 1100.3 Section 1100.3 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE GENERAL PROVISIONS § 1100.3 Liberal construction. The rules will...

  20. 49 CFR 1100.3 - Liberal construction.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 8 2014-10-01 2014-10-01 false Liberal construction. 1100.3 Section 1100.3 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION RULES OF PRACTICE GENERAL PROVISIONS § 1100.3 Liberal construction. The rules will...

  1. Rules and Regulations: Minimum Schoolhouse Construction Standards.

    ERIC Educational Resources Information Center

    Arkansas State Dept. of Education, Little Rock.

    Regulatory guidelines governing the minimum schoolhouse construction standards as well as rules for new construction applications, school site selection, and approval procedures are presented. Appendices (comprising 95 percent of the publication) document the following: educational space guidelines; planning for modern education; school…

  2. 77 FR 49741 - Cranes and Derricks in Construction: Demolition and Underground Construction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... Analysis When it issued the final cranes rule, OSHA prepared a final economic analysis (FEA) as required by... construction and cranes engaged in construction work involving demolition. The FEA for the final cranes..., found that the requirements of the rule were technologically and economically feasible. Because the FEA...

  3. 27 CFR 53.95 - Constructive sale price; basic rules.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Constructive sale price... AMMUNITION Special Provisions Applicable to Manufacturers Taxes § 53.95 Constructive sale price; basic rules... to construct a sale price on which to compute a tax imposed under chapter 32 of the Code on the price...

  4. A recurrent self-organizing neural fuzzy inference network.

    PubMed

    Juang, C F; Lin, C T

    1999-01-01

    A recurrent self-organizing neural fuzzy inference network (RSONFIN) is proposed in this paper. The RSONFIN is inherently a recurrent multilayered connectionist network for realizing the basic elements and functions of dynamic fuzzy inference, and may be considered to be constructed from a series of dynamic fuzzy rules. The temporal relations embedded in the network are built by adding some feedback connections representing the memory elements to a feedforward neural fuzzy network. Each weight as well as node in the RSONFIN has its own meaning and represents a special element in a fuzzy rule. There are no hidden nodes (i.e., no membership functions and fuzzy rules) initially in the RSONFIN. They are created on-line via concurrent structure identification (the construction of dynamic fuzzy if-then rules) and parameter identification (the tuning of the free parameters of membership functions). The structure learning together with the parameter learning forms a fast learning algorithm for building a small, yet powerful, dynamic neural fuzzy network. Two major characteristics of the RSONFIN can thus be seen: 1) the recurrent property of the RSONFIN makes it suitable for dealing with temporal problems and 2) no predetermination, like the number of hidden nodes, must be given, since the RSONFIN can find its optimal structure and parameters automatically and quickly. Moreover, to reduce the number of fuzzy rules generated, a flexible input partition method, the aligned clustering-based algorithm, is proposed. Various simulations on temporal problems are done and performance comparisons with some existing recurrent networks are also made. Efficiency of the RSONFIN is verified from these results.

  5. 12 CFR 1209.2 - Rules of construction.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 9 2012-01-01 2012-01-01 false Rules of construction. 1209.2 Section 1209.2 Banks and Banking FEDERAL HOUSING FINANCE AGENCY ORGANIZATION AND OPERATIONS RULES OF PRACTICE AND...) Any use of a masculine, feminine, or neuter gender encompasses all three, if such use would be...

  6. 12 CFR 1209.2 - Rules of construction.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Rules of construction. 1209.2 Section 1209.2 Banks and Banking FEDERAL HOUSING FINANCE AGENCY ORGANIZATION AND OPERATIONS RULES OF PRACTICE AND...) Any use of a masculine, feminine, or neuter gender encompasses all three, if such use would be...

  7. 12 CFR 1209.2 - Rules of construction.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 10 2014-01-01 2014-01-01 false Rules of construction. 1209.2 Section 1209.2 Banks and Banking FEDERAL HOUSING FINANCE AGENCY ORGANIZATION AND OPERATIONS RULES OF PRACTICE AND...) Any use of a masculine, feminine, or neuter gender encompasses all three, if such use would be...

  8. Universal Computation and Construction in GoL Cellular Automata

    NASA Astrophysics Data System (ADS)

    Goucher, Adam P.

    This chapter is concerned with the developments of universal computation and construction within Conway's Game of Life (GoL). I will begin by describing the history of the concepts and mechanisms for universal computation and construction in GoL, before explaining how a Universal Computer-Constructor (UCC) would operate in this automaton. Moreover, I shall present the design of a working UCC in the rule. It is both capable of computing any calculation (i.e. it is Turing-complete) and constructing most, if not all, of the constructible configurations within the rule. It cannot construct patterns which have no predecessor; neither can any machine in the rule (for obvious reasons). As such, it is more accurately a general constructor, rather than a universal constructor.

  9. 15 CFR 270.1 - Description of rule; purpose; applicability.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NATIONAL CONSTRUCTION SAFETY TEAMS NATIONAL CONSTRUCTION SAFETY TEAMS General § 270.1 Description of rule; purpose; applicability. (a) The National Construction Safety Team Act (the Act) (Pub. L. 107-231) provides for the establishment of...

  10. 15 CFR 270.1 - Description of rule; purpose; applicability.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NATIONAL CONSTRUCTION SAFETY TEAMS NATIONAL CONSTRUCTION SAFETY TEAMS General § 270.1 Description of rule; purpose; applicability. (a) The National Construction Safety Team Act (the Act) (Pub. L. 107-231) provides for the establishment of...

  11. 15 CFR 270.1 - Description of rule; purpose; applicability.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NATIONAL CONSTRUCTION SAFETY TEAMS NATIONAL CONSTRUCTION SAFETY TEAMS General § 270.1 Description of rule; purpose; applicability. (a) The National Construction Safety Team Act (the Act) (Pub. L. 107-231) provides for the establishment of...

  12. 15 CFR 270.1 - Description of rule; purpose; applicability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NATIONAL CONSTRUCTION SAFETY TEAMS NATIONAL CONSTRUCTION SAFETY TEAMS General § 270.1 Description of rule; purpose; applicability. (a) The National Construction Safety Team Act (the Act) (Pub. L. 107-231) provides for the establishment of...

  13. 15 CFR 270.1 - Description of rule; purpose; applicability.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NATIONAL CONSTRUCTION SAFETY TEAMS NATIONAL CONSTRUCTION SAFETY TEAMS General § 270.1 Description of rule; purpose; applicability. (a) The National Construction Safety Team Act (the Act) (Pub. L. 107-231) provides for the establishment of...

  14. Safety leadership at construction sites: the importance of rule-oriented and participative leadership.

    PubMed

    Grill, Martin; Pousette, Anders; Nielsen, Kent; Grytnes, Regine; Törner, Marianne

    2017-07-01

    Objectives The construction industry accounted for >20% of all fatal occupational accidents in Europe in 2014. Leadership is an essential antecedent to occupational safety. The aim of the present study was to assess the influence of transformational, active transactional, rule-oriented, participative, and laissez-faire leadership on safety climate, safety behavior, and accidents in the Swedish and Danish construction industry. Sweden and Denmark are similar countries but have a large difference in occupational accidents rates. Methods A questionnaire study was conducted among a random sample of construction workers in both countries: 811 construction workers from 85 sites responded, resulting in site and individual response rates of 73% and 64%, respectively. Results The results indicated that transformational, active transactional, rule-oriented and participative leadership predict positive safety outcomes, and laissez-faire leadership predict negative safety outcomes. For example, rule-oriented leadership predicts a superior safety climate (β=0.40, P<0.001), enhanced safety behavior (β=0.15, P<0.001), and fewer accidents [odds ratio (OR) 0.78, 95% confidence interval (95% CI) 0.62-0.98]. The effect of rule-oriented leadership on workers' safety behavior was moderated by the level of participative leadership (β=0.10, P<0.001), suggesting that when rules and plans are established in a collaborative manner, workers' motivation to comply with safety regulations and participate in proactive safety activities is elevated. The influence of leadership behaviors on safety outcomes were largely similar in Sweden and Denmark. Rule-oriented and participative leadership were more common in the Swedish than Danish construction industry, which may partly explain the difference in occupational accident rates. Conclusions Applying less laissez-faire leadership and more transformational, active transactional, participative and rule-oriented leadership appears to be an effective way for construction site managers to improve occupational safety in the industry.

  15. 17 CFR 248.2 - Model privacy form: rule of construction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Model privacy form: rule of... Safeguarding Personal Information § 248.2 Model privacy form: rule of construction. (a) Model privacy form. Use of the model privacy form in Appendix A to Subpart A of this part, consistent with the instructions...

  16. 22 CFR 228.17 - Special procurement rules for construction and engineering services.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... engineering services. 228.17 Section 228.17 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES FOR... construction and engineering services. Advanced developing countries, as defined in § 228.01, which USAID has... engineering services are not eligible to furnish USAID-financed construction and engineering services unless...

  17. 22 CFR 228.17 - Special procurement rules for construction and engineering services.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... engineering services. 228.17 Section 228.17 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES FOR... construction and engineering services. Advanced developing countries, as defined in § 228.01, which USAID has... engineering services are not eligible to furnish USAID-financed construction and engineering services unless...

  18. 22 CFR 228.17 - Special procurement rules for construction and engineering services.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... engineering services. 228.17 Section 228.17 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES FOR... construction and engineering services. Advanced developing countries, as defined in § 228.01, which USAID has... engineering services are not eligible to furnish USAID-financed construction and engineering services unless...

  19. 26 CFR 1.544-6 - Constructive ownership as actual ownership.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... father the constructive owner of such stock by a second application of the family and partnership rule. ... or of applying the family and partnership rule provided in section 544(a)(2), in order to make...), relating to stock not owned by an individual, or the family and partnership rule provided in section 544(a...

  20. The golden rule of reviewing

    USGS Publications Warehouse

    McPeek, Mark A.; DeAngelis, Donald L.; Shaw, Ruth G.; Moore, Allen J.; Rausher, Mark D.; Strong, Donald R.; Ellison, Aaron M.; Barrett, Louise; Rieseberg, Loren; Breed, Michael D.; Sullivan, Jack; Osenberg, Craig W.; Holyoak, Marcel; Elgar, Mark A.

    2009-01-01

    A major bottleneck in the time required to publish a scientific or scholarly paper is the speed with which reviews by peers are returned to journals. Peer review is a reciprocal altruistic system in which each individual may perform every task—editors, reviewers, and authors—at different times. Journals have no way to coerce reviewers to return their critiques faster. To greatly shorten the time to publication, all actors in this altruistic network should abide by the Golden Rule of Reviewing: review for others as you would have others review for you. Say yes to reviewing whenever your duties and schedule allow; provide a thorough, fair, and constructive critique of the work; and do it at your first opportunity regardless of the deadline.

  1. The reasonable effectiveness of mathematics in the natural sciences

    NASA Astrophysics Data System (ADS)

    Harvey, Alex

    2011-12-01

    Mathematics and its relation to the physical universe have been the topic of speculation since the days of Pythagoras. Several different views of the nature of mathematics have been considered: Realism—mathematics exists and is discovered; Logicism—all mathematics may be deduced through pure logic; Formalism—mathematics is just the manipulation of formulas and rules invented for the purpose; Intuitionism—mathematics comprises mental constructs governed by self evident rules. The debate among the several schools has major importance in understanding what Eugene Wigner called, The Unreasonable Effectiveness of Mathematics in the Natural Sciences. In return, this `Unreasonable Effectiveness' suggests a possible resolution of the debate in favor of Realism. The crucial element is the extraordinary predictive capacity of mathematical structures descriptive of physical theories.

  2. The dynamics of minority opinions in democratic debate

    NASA Astrophysics Data System (ADS)

    Galam, Serge

    2004-05-01

    A model for the dynamics of opinion forming in democratic public debate is presented. Using concepts and techniques from the physics of disorder the dynamics of social refusal spreading is studied within a perfect world, where the minority holds neither better arguments nor lobbying backing. The one-person-one-vote rule, together with local majority rules, are used to determine the outcome of local group discussions. In case of a local tie, the group decides on keeping the Status Quo. The geometry of social life shaped by offices, houses, bars, and restaurants is shown to determine the distribution size of these discussion groups. It is found to yield very asymmetric unstable thresholds to the total spreading of one opinion at the benefit of the refusal one. The associated dynamics is rather quick and completed within few days. This democratic paradox of public debate driven majority opinion reversal is discussed in light of some European construction issues. The model may apply to rumor and fear propagation.

  3. 12 CFR 509.12 - Construction of time limits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Construction of time limits. 509.12 Section 509.12 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY RULES OF PRACTICE AND PROCEDURE IN ADJUDICATORY PROCEEDINGS Uniform Rules of Practice and Procedure § 509.12 Construction of time...

  4. 12 CFR 263.12 - Construction of time limits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Construction of time limits. 263.12 Section 263.12 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM RULES OF PRACTICE FOR HEARINGS Uniform Rules of Practice and Procedure § 263.12 Construction of...

  5. 12 CFR 796.6 - What other definitions and rules of construction apply for purposes of this part?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 7 2014-01-01 2014-01-01 false What other definitions and rules of... RESTRICTIONS FOR CERTAIN NCUA EXAMINERS § 796.6 What other definitions and rules of construction apply for... federally insured credit union or other company only if the person works directly on matters for, or on...

  6. 12 CFR 796.6 - What other definitions and rules of construction apply for purposes of this part?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false What other definitions and rules of... RESTRICTIONS FOR CERTAIN NCUA EXAMINERS § 796.6 What other definitions and rules of construction apply for... federally insured credit union or other company only if the person works directly on matters for, or on...

  7. 12 CFR 796.6 - What other definitions and rules of construction apply for purposes of this part?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 7 2013-01-01 2013-01-01 false What other definitions and rules of... RESTRICTIONS FOR CERTAIN NCUA EXAMINERS § 796.6 What other definitions and rules of construction apply for... federally insured credit union or other company only if the person works directly on matters for, or on...

  8. 12 CFR 796.6 - What other definitions and rules of construction apply for purposes of this part?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 7 2012-01-01 2012-01-01 false What other definitions and rules of... RESTRICTIONS FOR CERTAIN NCUA EXAMINERS § 796.6 What other definitions and rules of construction apply for... federally insured credit union or other company only if the person works directly on matters for, or on...

  9. 12 CFR 796.6 - What other definitions and rules of construction apply for purposes of this part?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false What other definitions and rules of... RESTRICTIONS FOR CERTAIN NCUA EXAMINERS § 796.6 What other definitions and rules of construction apply for... federally insured credit union or other company only if the person works directly on matters for, or on...

  10. Impact of Operating Rules on Planning Capacity Expansion of Urban Water Supply Systems

    NASA Astrophysics Data System (ADS)

    de Neufville, R.; Galelli, S.; Tian, X.

    2017-12-01

    This study addresses the impact of operating rules on capacity planning of urban water supply systems. The continuous growth of metropolitan areas represents a major challenge for water utilities, which often rely on industrial water supply (e.g., desalination, reclaimed water) to complement natural resources (e.g., reservoirs). These additional sources increase the reliability of supply, equipping operators with additional means to hedge against droughts. How do their rules for using industrial water supply impact the performance of water supply system? How might it affect long-term plans for capacity expansion? Possibly significantly, as demonstrated by the analysis of the operations and planning of a water supply system inspired by Singapore. Our analysis explores the system dynamics under multiple inflow and management scenarios to understand the extent to which alternative operating rules for the use of industrial water supply affect system performance. Results first show that these operating rules can have significant impact on the variability in system performance (e.g., reliability, energy use) comparable to that of hydro-climatological conditions. Further analyses of several capacity expansion exercises—based on our original hydrological and management scenarios—show that operating rules significantly affect the timing and magnitude of critical decisions, such as the construction of new desalination plants. These results have two implications: Capacity expansion analysis should consider the effect of a priori uncertainty about operating rules; and operators should consider how their flexibility in operating rules can affect their perceived need for capacity.

  11. Associations between general parenting, restrictive snacking rules, and adolescent's snack intake. The roles of fathers and mothers and interparental congruence.

    PubMed

    Gevers, Dorus W M; van Assema, Patricia; Sleddens, Ester F C; de Vries, Nanne K; Kremers, Stef P J

    2015-04-01

    Little research has been done on the role of fathers and parenting congruence between mothers and fathers. This study aimed to clarify the roles of general parenting and restrictive snacking rules set by fathers and mothers, and to explore parenting congruence in explaining adolescents' snack intake. Adolescents aged 11 to 15 completed a questionnaire assessing their perception of general parenting constructs (i.e. nurturance, structure, behavioral control, coercive control, and overprotection), restrictive snacking rules set by their fathers and mothers, and their own energy-dense snack intakes between meals. Scores for mothers were significantly higher on all constructs than for fathers, except for coercive control. Generally, higher scores on general parenting constructs were associated with higher scores on restrictive snacking rules (most of the associations being significant). Most general parenting constructs were unrelated to the respondents' number of snacks consumed. The use of restrictive snacking rules by both fathers and mothers was significantly and negatively related to respondents' snack intake. Moderation analyses indicated that high levels of incongruence between parents attenuated the favorable impact of fathers' rules and nurturance on their children's snacking, but interactions of congruence with three other paternal scales and all maternal scales were absent. Our findings indicate that both paternal and maternal general parenting and restrictive snacking rules play important roles in adolescents' snacking, and that high parental incongruence regarding restrictive snacking rules and nurturance could be undesirable. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. 12 CFR 264a.6 - What other definitions and rules of construction apply for purposes of this part?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false What other definitions and rules of... EXAMINERS § 264a.6 What other definitions and rules of construction apply for purposes of this part? For purposes of this part— (a) Bank holding company means any company that controls a bank (as provided in...

  13. 5 CFR 9701.502 - Rule of construction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9701.502 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT SYSTEM (DEPARTMENT OF HOMELAND SECURITY-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT SYSTEM Labor-Management Relations § 9701.502 Rule of construction. In interpreting this...

  14. Safety Early Warning Research for Highway Construction Based on Case-Based Reasoning and Variable Fuzzy Sets

    PubMed Central

    Liu, Yan; Xu, Zhen-Jun

    2013-01-01

    As a high-risk subindustry involved in construction projects, highway construction safety has experienced major developments in the past 20 years, mainly due to the lack of safe early warnings in Chinese construction projects. By combining the current state of early warning technology with the requirements of the State Administration of Work Safety and using case-based reasoning (CBR), this paper expounds on the concept and flow of highway construction safety early warnings based on CBR. The present study provides solutions to three key issues, index selection, accident cause association analysis, and warning degree forecasting implementation, through the use of association rule mining, support vector machine classifiers, and variable fuzzy qualitative and quantitative change criterion modes, which fully cover the needs of safe early warning systems. Using a detailed description of the principles and advantages of each method and by proving the methods' effectiveness and ability to act together in safe early warning applications, effective means and intelligent technology for a safe highway construction early warning system are established. PMID:24191134

  15. Safety early warning research for highway construction based on case-based reasoning and variable fuzzy sets.

    PubMed

    Liu, Yan; Yi, Ting-Hua; Xu, Zhen-Jun

    2013-01-01

    As a high-risk subindustry involved in construction projects, highway construction safety has experienced major developments in the past 20 years, mainly due to the lack of safe early warnings in Chinese construction projects. By combining the current state of early warning technology with the requirements of the State Administration of Work Safety and using case-based reasoning (CBR), this paper expounds on the concept and flow of highway construction safety early warnings based on CBR. The present study provides solutions to three key issues, index selection, accident cause association analysis, and warning degree forecasting implementation, through the use of association rule mining, support vector machine classifiers, and variable fuzzy qualitative and quantitative change criterion modes, which fully cover the needs of safe early warning systems. Using a detailed description of the principles and advantages of each method and by proving the methods' effectiveness and ability to act together in safe early warning applications, effective means and intelligent technology for a safe highway construction early warning system are established.

  16. Parallel inferencing method and apparatus for rule-based expert systems

    NASA Technical Reports Server (NTRS)

    Schwuttke, Ursula M. (Inventor); Moldovan, Dan (Inventor); Kuo, Steve (Inventor)

    1993-01-01

    The invention analyzes areas of conditions with an expert knowledge base of rules using plural separate nodes which fire respective rules of said knowledge base, each of said rules upon being fired altering certain of said conditions predicated upon the existence of other said conditions. The invention operates by constructing a P representation of all pairs of said rules which are input dependent or output dependent; constructing a C representation of all pairs of said rules which are communication dependent or input dependent; determining which of the rules are ready to fire by matching the predicate conditions of each rule with the conditions of said set; enabling said node means to simultaneously fire those of the rules ready to fire which are defined by said P representation as being free of input and output dependencies; and communicating from each node enabled by said enabling step the alteration of conditions by the corresponding rule to other nodes whose rules are defined by said C matrix means as being input or communication dependent upon the rule of said enabled node.

  17. 17 CFR 250.89 - Termination of contracts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction Contracts § 250.89 Termination of contracts. Every service, sales, or construction contract made after April... contain provision for its termination to the extent that performance may conflict with any rule...

  18. 17 CFR 250.89 - Termination of contracts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction Contracts § 250.89 Termination of contracts. Every service, sales, or construction contract made after April... contain provision for its termination to the extent that performance may conflict with any rule...

  19. DOD Residential Proton Exchange Membrane (PEM) Fuel Cell Demonstration Program. Volume 1. Summary of the Fiscal Year 2001 Program

    DTIC Science & Technology

    2004-02-01

    Potential new stan- dard ASME Boiler and Pressure Vessel Code, Section VIII ( BPVC -VIII), Division 1 Rules for Construction of Pressure Vessels...Published and avail- able for sale. ASME BPVC -VIII Division 2 Rules for Construction of Pressure Vessels, Division 2, Gerry Eisenberg, ASME ...Vessels, Division 3, Alternate ASME BPVC -VIII Division 3 Gerry Eisenberg, ASME Published and avail- able for sale. Rules High

  20. Patterns of astragalar fibular facet orientation in extant and fossil primates and their evolutionary implications.

    PubMed

    Boyer, Doug M; Seiffert, Erik R

    2013-07-01

    A laterally sloping fibular facet of the astragalus (=talus) has been proposed as one of few osteological synapomorphies of strepsirrhine primates, but the feature has never been comprehensively quantified. We describe a method for calculating fibular facet orientation on digital models of astragali as the angle between the planes of the fibular facet and the lateral tibial facet. We calculated this value in a sample that includes all major extant primate clades, a diversity of Paleogene primates, and nonprimate euarchontans (n = 304). Results show that previous characterization of a divide between extant haplorhines and strepsirrhines is accurate, with little overlap even when individual data points are considered. Fibular facet orientation is conserved in extant strepsirrhines despite major differences in locomotion and body size, while extant anthropoids are more variable (e.g., low values for catarrhines relative to non-callitrichine platyrrhines). Euprimate outgroups exhibit a mosaic of character states with Cynocephalus having a more obtuse strepsirrhine-like facet and sampled treeshrews and plesiadapiforms having more acute haplorhine-like facets. Surprisingly, the earliest species of the adapiform Cantius have steep haplorhine-like facets as well. We used a Bayesian approach to reconstruct the evolution of fibular facet orientation as a continuous character across a supertree of living and extinct primates. Mean estimates for crown Primatomorpha (97.9°), Primates (99.5°), Haplorhini (98.7°), and Strepsirrhini (108.2°) support the hypothesis that the strepsirrhine condition is derived, while lower values for crown Anthropoidea (92.8°) and Catarrhini (88.9°) are derived in the opposite direction. Copyright © 2013 Wiley Periodicals, Inc.

  1. Automated rule-base creation via CLIPS-Induce

    NASA Technical Reports Server (NTRS)

    Murphy, Patrick M.

    1994-01-01

    Many CLIPS rule-bases contain one or more rule groups that perform classification. In this paper we describe CLIPS-Induce, an automated system for the creation of a CLIPS classification rule-base from a set of test cases. CLIPS-Induce consists of two components, a decision tree induction component and a CLIPS production extraction component. ID3, a popular decision tree induction algorithm, is used to induce a decision tree from the test cases. CLIPS production extraction is accomplished through a top-down traversal of the decision tree. Nodes of the tree are used to construct query rules, and branches of the tree are used to construct classification rules. The learned CLIPS productions may easily be incorporated into a large CLIPS system that perform tasks such as accessing a database or displaying information.

  2. 78 FR 22369 - National Emissions Standards for Hazardous Air Pollutants: Mineral Wool Production and Wool...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ... Emissions Standards for Hazardous Air Pollutants: Mineral Wool Production and Wool Fiberglass Manufacturing... Fiberglass Manufacturing (Subpart NNN) major source rules? A. Subpart DDD--Mineral Wool Production Major... Wool Production Major Source Rule B. Subpart NNN--Wool Fiberglass Manufacturing Major Source Rule VIII...

  3. 22 CFR 228.39 - Special source rules for construction and engineering services.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... engineering services. 228.39 Section 228.39 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON... engineering services. Advanced developing countries, eligible under Geographic Code 941, which have attained a competitive capability in international markets for construction services or engineering services are not...

  4. 22 CFR 228.39 - Special source rules for construction and engineering services.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... engineering services. 228.39 Section 228.39 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON... engineering services. Advanced developing countries, eligible under Geographic Code 941, which have attained a competitive capability in international markets for construction services or engineering services are not...

  5. Lead-based paint awareness, work practices, and compliance during residential construction and renovation.

    PubMed

    Blando, James D; Antoine, Nickita; Lefkowitz, Daniel

    2013-05-01

    The U.S. Environmental Protection Agency recently implemented the Renovation, Repair and Painting (RRP) rule that applies to pre-1978 residences because of the potential presence of lead-based paint. Enforcement of this rule may be difficult and therefore it is crucial to understand the awareness and beliefs of contractors and the general public because these will likely be major determinants of exposures resulting from residential renovation work. The study described in this article utilized two mailed surveys: one directed to the general public and the other directed to contractors. The surveys were conducted in New Jersey and Virginia. Field observations were also recorded for work sites in New Jersey. Results indicated a high awareness among the general public about the hazards of lead, a low level of screening by children's doctors for lead exposure, frequent use of work practices that generate lots of dust, poor hygiene among contractors, and the potential for low compliance of contractors with the RRP rule. In particular, contractors who do not believe lead is a serious health hazard are expected to have the lowest compliance with the RRP rule. These findings serve as targets for effective public health interventions through education and outreach.

  6. Integrative modeling of gene and genome evolution roots the archaeal tree of life

    PubMed Central

    Szöllősi, Gergely J.; Spang, Anja; Foster, Peter G.; Heaps, Sarah E.; Boussau, Bastien; Ettema, Thijs J. G.; Embley, T. Martin

    2017-01-01

    A root for the archaeal tree is essential for reconstructing the metabolism and ecology of early cells and for testing hypotheses that propose that the eukaryotic nuclear lineage originated from within the Archaea; however, published studies based on outgroup rooting disagree regarding the position of the archaeal root. Here we constructed a consensus unrooted archaeal topology using protein concatenation and a multigene supertree method based on 3,242 single gene trees, and then rooted this tree using a recently developed model of genome evolution. This model uses evidence from gene duplications, horizontal transfers, and gene losses contained in 31,236 archaeal gene families to identify the most likely root for the tree. Our analyses support the monophyly of DPANN (Diapherotrites, Parvarchaeota, Aenigmarchaeota, Nanoarchaeota, Nanohaloarchaea), a recently discovered cosmopolitan and genetically diverse lineage, and, in contrast to previous work, place the tree root between DPANN and all other Archaea. The sister group to DPANN comprises the Euryarchaeota and the TACK Archaea, including Lokiarchaeum, which our analyses suggest are monophyletic sister lineages. Metabolic reconstructions on the rooted tree suggest that early Archaea were anaerobes that may have had the ability to reduce CO2 to acetate via the Wood–Ljungdahl pathway. In contrast to proposals suggesting that genome reduction has been the predominant mode of archaeal evolution, our analyses infer a relatively small-genomed archaeal ancestor that subsequently increased in complexity via gene duplication and horizontal gene transfer. PMID:28533395

  7. Patterns and effects of GC3 heterogeneity and parsimony informative sites on the phylogenetic tree of genes.

    PubMed

    Ma, Shuai; Wu, Qi; Hu, Yibo; Wei, Fuwen

    2018-05-20

    The explosive growth in genomic data has provided novel insights into the conflicting signals hidden in phylogenetic trees. Although some studies have explored the effects of the GC content and parsimony informative sites (PIS) on the phylogenetic tree, the effect of the heterogeneity of the GC content at the first/second/third codon position on parsimony informative sites (GC1/2/3 PIS ) among different species and the effect of PIS on phylogenetic tree construction remain largely unexplored. Here, we used two different mammal genomic datasets to explore the patterns of GC1/2/3 PIS heterogeneity and the effect of PIS on the phylogenetic tree of genes: (i) all GC1/2/3 PIS have obvious heterogeneity between different mammals, and the levels of heterogeneity are GC3 PIS  > GC2 PIS  > GC1 PIS ; (ii) the number of PIS is positively correlated with the metrics of "good" gene tree topologies, and excluding the third codon position (C3) decreases the quality of gene trees by removing too many PIS. These results provide novel insights into the heterogeneity pattern of GC1/2/3 PIS in mammals and the relationship between GC3/PIS and gene trees. Additionally, it is necessary to carefully consider whether to exclude C3 to improve the quality of gene trees, especially in the super-tree method. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Integrative modeling of gene and genome evolution roots the archaeal tree of life.

    PubMed

    Williams, Tom A; Szöllősi, Gergely J; Spang, Anja; Foster, Peter G; Heaps, Sarah E; Boussau, Bastien; Ettema, Thijs J G; Embley, T Martin

    2017-06-06

    A root for the archaeal tree is essential for reconstructing the metabolism and ecology of early cells and for testing hypotheses that propose that the eukaryotic nuclear lineage originated from within the Archaea; however, published studies based on outgroup rooting disagree regarding the position of the archaeal root. Here we constructed a consensus unrooted archaeal topology using protein concatenation and a multigene supertree method based on 3,242 single gene trees, and then rooted this tree using a recently developed model of genome evolution. This model uses evidence from gene duplications, horizontal transfers, and gene losses contained in 31,236 archaeal gene families to identify the most likely root for the tree. Our analyses support the monophyly of DPANN (Diapherotrites, Parvarchaeota, Aenigmarchaeota, Nanoarchaeota, Nanohaloarchaea), a recently discovered cosmopolitan and genetically diverse lineage, and, in contrast to previous work, place the tree root between DPANN and all other Archaea. The sister group to DPANN comprises the Euryarchaeota and the TACK Archaea, including Lokiarchaeum , which our analyses suggest are monophyletic sister lineages. Metabolic reconstructions on the rooted tree suggest that early Archaea were anaerobes that may have had the ability to reduce CO 2 to acetate via the Wood-Ljungdahl pathway. In contrast to proposals suggesting that genome reduction has been the predominant mode of archaeal evolution, our analyses infer a relatively small-genomed archaeal ancestor that subsequently increased in complexity via gene duplication and horizontal gene transfer.

  9. 29 CFR 4203.3 - Plan adoption of special withdrawal rules.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... rule adopted pursuant to this part shall be similar to the rules for the construction and entertainment industries described in section 4203 (b) and (c) of ERISA. A partial withdrawal liability rule adopted pursuant to this part shall be consistent with the complete withdrawal rule adopted by the plan. A plan...

  10. 12 CFR 908.3 - Rules of construction.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... OPERATIONS RULES OF PRACTICE AND PROCEDURE IN HEARINGS ON THE RECORD Introduction § 908.3 Rules of... gender encompasses all three, if such use would be appropriate; and (c) Unless the context requires...

  11. 12 CFR 908.3 - Rules of construction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OPERATIONS RULES OF PRACTICE AND PROCEDURE IN HEARINGS ON THE RECORD Introduction § 908.3 Rules of... gender encompasses all three, if such use would be appropriate; and (c) Unless the context requires...

  12. Constructing Compact Takagi-Sugeno Rule Systems: Identification of Complex Interactions in Epidemiological Data

    PubMed Central

    Zhou, Shang-Ming; Lyons, Ronan A.; Brophy, Sinead; Gravenor, Mike B.

    2012-01-01

    The Takagi-Sugeno (TS) fuzzy rule system is a widely used data mining technique, and is of particular use in the identification of non-linear interactions between variables. However the number of rules increases dramatically when applied to high dimensional data sets (the curse of dimensionality). Few robust methods are available to identify important rules while removing redundant ones, and this results in limited applicability in fields such as epidemiology or bioinformatics where the interaction of many variables must be considered. Here, we develop a new parsimonious TS rule system. We propose three statistics: R, L, and ω-values, to rank the importance of each TS rule, and a forward selection procedure to construct a final model. We use our method to predict how key components of childhood deprivation combine to influence educational achievement outcome. We show that a parsimonious TS model can be constructed, based on a small subset of rules, that provides an accurate description of the relationship between deprivation indices and educational outcomes. The selected rules shed light on the synergistic relationships between the variables, and reveal that the effect of targeting specific domains of deprivation is crucially dependent on the state of the other domains. Policy decisions need to incorporate these interactions, and deprivation indices should not be considered in isolation. The TS rule system provides a basis for such decision making, and has wide applicability for the identification of non-linear interactions in complex biomedical data. PMID:23272108

  13. Constructing compact Takagi-Sugeno rule systems: identification of complex interactions in epidemiological data.

    PubMed

    Zhou, Shang-Ming; Lyons, Ronan A; Brophy, Sinead; Gravenor, Mike B

    2012-01-01

    The Takagi-Sugeno (TS) fuzzy rule system is a widely used data mining technique, and is of particular use in the identification of non-linear interactions between variables. However the number of rules increases dramatically when applied to high dimensional data sets (the curse of dimensionality). Few robust methods are available to identify important rules while removing redundant ones, and this results in limited applicability in fields such as epidemiology or bioinformatics where the interaction of many variables must be considered. Here, we develop a new parsimonious TS rule system. We propose three statistics: R, L, and ω-values, to rank the importance of each TS rule, and a forward selection procedure to construct a final model. We use our method to predict how key components of childhood deprivation combine to influence educational achievement outcome. We show that a parsimonious TS model can be constructed, based on a small subset of rules, that provides an accurate description of the relationship between deprivation indices and educational outcomes. The selected rules shed light on the synergistic relationships between the variables, and reveal that the effect of targeting specific domains of deprivation is crucially dependent on the state of the other domains. Policy decisions need to incorporate these interactions, and deprivation indices should not be considered in isolation. The TS rule system provides a basis for such decision making, and has wide applicability for the identification of non-linear interactions in complex biomedical data.

  14. Rules and regulations as potential moderator on the relationship between organizational internal and external factors with effective construction risk management in Nigerian construction companies: A proposed framework

    NASA Astrophysics Data System (ADS)

    Adeleke, A. Q.; Bahaudin, A. Y.; Kamaruddeen, A. M.

    2016-08-01

    Certain organizational internal and external factors have been found to influence effective construction risk management within the construction company which has contributed to massive risk occurrence on the projects. Yet, the influence of the organizational factors such as effective communication, team competency with skills, active leadership, political factor, organizational culture, technology factor and economic factor on effective construction risk management among the construction companies operating in Abuja and Lagos state Nigeria have not received considerable attention. More so, a moderating variable is proposed. This paper proposes rules and regulations as the potential moderator on the relationship between organisational internal factors, external factors and effective construction risk management.

  15. 12 CFR 346.11 - Other definitions and rules of construction used in this part.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...” is any partnership, association, trust, joint venture, joint stock company, corporation, limited... definitions and rules of construction used in this part. (a) Affiliate. “Affiliate” means— (1) Any company that controls, is controlled by, or is under common control with another company; and (2) For the...

  16. Logic Analysis of Painting Modeling Rules and Avoiding Narrative Viewing

    ERIC Educational Resources Information Center

    Zhu, Feng; Shao, Jie

    2009-01-01

    Painting modeling rules are constructed based on objective representing with material substances as the main body and the construction methods and orders are mostly limited to narrative viewing and expression, which, obviously, is not the best method. Logistic thinking in virtue of modeling art could gender a more "painting-like"…

  17. 78 FR 59237 - Regulated Navigation Area-Weymouth Fore River, Fore River Bridge Construction, Weymouth and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ...-AA11 Regulated Navigation Area--Weymouth Fore River, Fore River Bridge Construction, Weymouth and... vicinity of the Fore River Bridge (Mile 3.5) between Weymouth and Quincy, MA. This rule will place temporary speed, wake, and entry restrictions on vessels during bridge replacement operations. This rule is...

  18. Automated medical resident rotation and shift scheduling to ensure quality resident education and patient care.

    PubMed

    Smalley, Hannah K; Keskinocak, Pinar

    2016-03-01

    At academic teaching hospitals around the country, the majority of clinical care is provided by resident physicians. During their training, medical residents often rotate through various hospitals and/or medical services to maximize their education. Depending on the size of the training program, manually constructing such a rotation schedule can be cumbersome and time consuming. Further, rules governing allowable duty hours for residents have grown more restrictive in recent years (ACGME 2011), making day-to-day shift scheduling of residents more difficult (Connors et al., J Thorac Cardiovasc Surg 137:710-713, 2009; McCoy et al., May Clin Proc 86(3):192, 2011; Willis et al., J Surg Edu 66(4):216-221, 2009). These rules limit lengths of duty periods, allowable duty hours in a week, and rest periods, to name a few. In this paper, we present two integer programming models (IPs) with the goals of (1) creating feasible assignments of residents to rotations over a one-year period, and (2) constructing night and weekend call-shift schedules for the individual rotations. These models capture various duty-hour rules and constraints, provide the ability to test multiple what-if scenarios, and largely automate the process of schedule generation, solving these scheduling problems more effectively and efficiently compared to manual methods. Applying our models on data from a surgical residency program, we highlight the infeasibilities created by increased duty-hour restrictions placed on residents in conjunction with current scheduling paradigms.

  19. The Majority Rule Act. EdSource Election Brief: Proposition 26.

    ERIC Educational Resources Information Center

    EdSource, Inc., Palo Alto, CA.

    This article summarizes "The Majority Rule Act for Smaller Classes, Safer Schools and Financial Accountability" (Proposition 26). The Majority Rule Act deals with the percentage vote that a school district, county office of education, or community college, needs in an election to authorize local general-obligation bonds for school…

  20. Dinosaurs and the Cretaceous Terrestrial Revolution

    PubMed Central

    Lloyd, Graeme T; Davis, Katie E; Pisani, Davide; Tarver, James E; Ruta, Marcello; Sakamoto, Manabu; Hone, David W.E; Jennings, Rachel; Benton, Michael J

    2008-01-01

    The observed diversity of dinosaurs reached its highest peak during the mid- and Late Cretaceous, the 50 Myr that preceded their extinction, and yet this explosion of dinosaur diversity may be explained largely by sampling bias. It has long been debated whether dinosaurs were part of the Cretaceous Terrestrial Revolution (KTR), from 125–80 Myr ago, when flowering plants, herbivorous and social insects, squamates, birds and mammals all underwent a rapid expansion. Although an apparent explosion of dinosaur diversity occurred in the mid-Cretaceous, coinciding with the emergence of new groups (e.g. neoceratopsians, ankylosaurid ankylosaurs, hadrosaurids and pachycephalosaurs), results from the first quantitative study of diversification applied to a new supertree of dinosaurs show that this apparent burst in dinosaurian diversity in the last 18 Myr of the Cretaceous is a sampling artefact. Indeed, major diversification shifts occurred largely in the first one-third of the group's history. Despite the appearance of new clades of medium to large herbivores and carnivores later in dinosaur history, these new originations do not correspond to significant diversification shifts. Instead, the overall geometry of the Cretaceous part of the dinosaur tree does not depart from the null hypothesis of an equal rates model of lineage branching. Furthermore, we conclude that dinosaurs did not experience a progressive decline at the end of the Cretaceous, nor was their evolution driven directly by the KTR. PMID:18647715

  1. Asbestos worker protection. Environmental Protection Agency (EPA). Final rule.

    PubMed

    2000-11-15

    In this Final Rule, EPA is amending both the Asbestos Worker Protection Rule (WPR) and the Asbestos-in-Schools Rule. The WPR amendment protects State and local government employees from the health risks of exposure to asbestos to the same extent as private sector workers by adopting for these employees the Asbestos Standards of the Occupational Safety and Health Administration (OSHA). The WPR's coverage is extended to State and local government employees who are performing construction work, custodial work, and automotive brake and clutch repair work. This final rule cross-references the OSHA Asbestos Standards for Construction and for General Industry, so that future amendments to these OSHA standards are directly and equally effective for employees covered by the WPR. EPA also amends the Asbestos-in-Schools Rule to provide coverage under the WPR for employees of public local education agencies who perform operations, maintenance, and repair activities. EPA is issuing this final rule under section 6 of the Toxic Substances Control Act (TSCA).

  2. Origami rules for the construction of localized eigenstates of the Hubbard model in decorated lattices

    NASA Astrophysics Data System (ADS)

    Dias, R. G.; Gouveia, J. D.

    2015-11-01

    We present a method of construction of exact localized many-body eigenstates of the Hubbard model in decorated lattices, both for U = 0 and U → ∞. These states are localized in what concerns both hole and particle movement. The starting point of the method is the construction of a plaquette or a set of plaquettes with a higher symmetry than that of the whole lattice. Using a simple set of rules, the tight-binding localized state in such a plaquette can be divided, folded and unfolded to new plaquette geometries. This set of rules is also valid for the construction of a localized state for one hole in the U → ∞ limit of the same plaquette, assuming a spin configuration which is a uniform linear combination of all possible permutations of the set of spins in the plaquette.

  3. 7 CFR 1753.77 - Methods of minor construction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., DEPARTMENT OF AGRICULTURE TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Minor Construction... Contract Form 773, “Miscellaneous Construction Work and Maintenance Services”, by RUS Contract Form 515, or by work order construction. The rules for using Form 515 for minor construction are contained in...

  4. Data Fabrication and Falsification and Empiricist Philosophy of Science

    PubMed Central

    Resnik, David B.

    2014-01-01

    Scientists have rules pertaining to data fabrication and falsification that are enforced with significant punishments, such as loss of funding, termination of employment, or imprisonment. These rules pertain to data that describe observable and unobservable entities. In this commentary I argue that scientists would not adopt rules that impose harsh penalties on researchers for data fabrication or falsification unless they believed that an aim of scientific research is to develop true theories and hypotheses about entities that exist, including unobservable ones. This argument presents a challenge for constructive empiricists, such as van Fraassen. Constructive empiricists need to be able to explain why rules pertaining to data fabrication and falsification do not threaten their philosophy of science. PMID:23982326

  5. Data fabrication and falsification and empiricist philosophy of science.

    PubMed

    Resnik, David B

    2014-06-01

    Scientists have rules pertaining to data fabrication and falsification that are enforced with significant punishments, such as loss of funding, termination of employment, or imprisonment. These rules pertain to data that describe observable and unobservable entities. In this commentary I argue that scientists would not adopt rules that impose harsh penalties on researchers for data fabrication or falsification unless they believed that an aim of scientific research is to develop true theories and hypotheses about entities that exist, including unobservable ones. This argument presents a challenge for constructive empiricists, such as van Fraassen. Constructive empiricists need to be able to explain why rules pertaining to data fabrication and falsification do not threaten their philosophy of science.

  6. Facilitation can increase the phylogenetic diversity of plant communities.

    PubMed

    Valiente-Banuet, Alfonso; Verdú, Miguel

    2007-11-01

    With the advent of molecular phylogenies the assessment of community assembly processes has become a central topic in community ecology. These processes have focused almost exclusively on habitat filtering and competitive exclusion. Recent evidence, however, indicates that facilitation has been important in preserving biodiversity over evolutionary time, with recent lineages conserving the regeneration niches of older, distant lineages. Here we test whether, if facilitation among distant-related species has preserved the regeneration niche of plant lineages, this has increased the phylogenetic diversity of communities. By analyzing a large worldwide database of species, we showed that the regeneration niches were strongly conserved across evolutionary history. Likewise, a phylogenetic supertree of all species of three communities driven by facilitation showed that nurse species facilitated distantly related species and increased phylogenetic diversity.

  7. 40 CFR 60.2997 - How does the model rule relate to the required elements of my State plan?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... Construction On or Before December 9, 2004 Model Rule-Use of Model Rule § 60.2997 How does the model rule...

  8. 40 CFR 60.2997 - How does the model rule relate to the required elements of my State plan?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 7 2013-07-01 2013-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... Construction On or Before December 9, 2004 Model Rule-Use of Model Rule § 60.2997 How does the model rule...

  9. 40 CFR 60.2997 - How does the model rule relate to the required elements of my State plan?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... Construction On or Before December 9, 2004 Model Rule-Use of Model Rule § 60.2997 How does the model rule...

  10. 40 CFR 60.2997 - How does the model rule relate to the required elements of my State plan?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 7 2012-07-01 2012-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... Construction On or Before December 9, 2004 Model Rule-Use of Model Rule § 60.2997 How does the model rule...

  11. 40 CFR 60.2997 - How does the model rule relate to the required elements of my State plan?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 7 2014-07-01 2014-07-01 false How does the model rule relate to the... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES... Construction On or Before December 9, 2004 Model Rule-Use of Model Rule § 60.2997 How does the model rule...

  12. Modeling the effects of changes in new source review on national SO2 and NOx emissions from electricity-generating units.

    PubMed

    Evans, David A; Hobbs, Benjamin F; Oren, Craig; Palmer, Karen L

    2008-01-15

    The Clean Air Act establishes New Source Review (NSR) programs that apply to construction or modification of major stationary sources. In 2002 and 2003, EPA revised its rules to narrow NSR's coverage of renovations. Congress mandated a National Research Council study of the revisions' impacts. In that study, we used an electricity-sector model to explore possible effects of the equipment replacement provision (ERP), the principal NSR change directed at power plants. We find that, assuming implementation of the Clean Air Interstate Rule (CAIR), tight enforcement of the prerevision NSR rules would likely lead to no or limited decreases in national emissions compared to policies such as ERP. However, emissions might shift forward in time because the previous NSR rules would depress allowance prices, discouraging banking and encouraging allowance use. Only under the most aggressive prerevision NSR enforcement scenario, in which essentially all coal capacity is compelled to retrofit controls by 2020, do NOx emissions fall below ERP levels. Even then, total 2007-2020 SO2 emissions are unaffected. Further decreases in national emissions could be accomplished more cheaply by tighter emissions caps than through NSR because caps provide incentives for efficient operating strategies, such as fuel switching, as well as retrofits.

  13. The Construct of Attention in Schizophrenia

    PubMed Central

    Luck, Steven J.; Gold, James M.

    2008-01-01

    Schizophrenia is widely thought to involve deficits of attention. However, the term attention can be defined so broadly that impaired performance on virtually any task could be construed as evidence for a deficit in attention, and this has slowed cumulative progress in understanding attention deficits in schizophrenia. To address this problem, we divide the general concept of attention into two distinct constructs: input selection, the selection of task-relevant inputs for further processing; and rule selection, the selective activation of task-appropriate rules. These constructs are closely tied to working memory, because input selection mechanisms are used to control the transfer of information into working memory and because working memory stores the rules used by rule selection mechanisms. These constructs are also closely tied to executive function, because executive systems are used to guide input selection and because rule selection is itself at key aspect of executive function. Within the domain of input selection, it is important to distinguish between the control of selection—the processes that guide attention to task-relevant inputs—and the implementation of selection—the processes that enhance the processing of the relevant inputs and suppress the irrelevant inputs. Current evidence suggests that schizophrenia involves a significant impairment in the control of selection but little or no impairment in the implementation of selection. Consequently, the CNTRICS participants agreed by consensus that attentional control should be a priority target for measurement and treatment research in schizophrenia. PMID:18374901

  14. How to win the blame game.

    PubMed

    Baldwin, D G

    2001-01-01

    At some companies, people are all too quick to point fingers, leaving employees more concerned about avoiding blame than about achieving results. Such organizations, ruled by "CYA," have given blame a bum rap. David Baldwin, a former Major League pitcher, says blame can be a powerful and constructive force. It can be an effective teaching tool that helps people avoid repeating their mistakes. When used judiciously--and sparingly--blame can also prod people to put forth their best efforts, while maintaining both their confidence and their focus on goals. Indeed, blame can have a very positive effect when it's done for the right reasons. The key, then, is the way that blame is managed, which can influence how people make decisions and perform their jobs and ultimately affect the culture and character of an organization. In the course of his research on how Major League Baseball managers make decisions, Baldwin became fascinated by the subject of blame--what functions it serves and how it's best managed. His observations led him to identify five rules of blame, which, he says, apply to any organization, whether it's the LA Dodgers, General Motors, or a small start-up. First, know when to blame--and when not to. Second, blame in private and praise in public. Third, realize that the absence of blame can be far worse than its presence. Fourth, manage misguided blame. And fifth, be aware that confidence is the first casualty of blame. Managers who follow these rules will use blame in the most positive and effective ways possible, Baldwin says. Without these rules, blame becomes an ever-more difficult balancing act: Too much erodes people's confidence, while too little hinders them from reaching their full potential.

  15. 26 CFR 48.4216(b)-3 - Constructive sale price; special rule for arm's-length sales.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... volume of sales which are at retail or to retailers, or both, is less than half the total industry dollar volume of sales at all levels of distribution by manufacturers, producers, or importers, including sales... 26 Internal Revenue 16 2010-04-01 2010-04-01 true Constructive sale price; special rule for arm's...

  16. Complex Problem Solving--More than Reasoning?

    ERIC Educational Resources Information Center

    Wustenberg, Sascha; Greiff, Samuel; Funke, Joachim

    2012-01-01

    This study investigates the internal structure and construct validity of Complex Problem Solving (CPS), which is measured by a "Multiple-Item-Approach." It is tested, if (a) three facets of CPS--"rule identification" (adequateness of strategies), "rule knowledge" (generated knowledge) and "rule application"…

  17. What You Should Know about Construction Disputes.

    ERIC Educational Resources Information Center

    Hohns, H. Murray

    1979-01-01

    A number of rules that will aid in the decision making of the individual confronted with the need to purchase construction services, administer a construction contract, or be responsible for the performance of those construction services. (Author)

  18. The Role of Variable Rules in Language Acquisition.

    ERIC Educational Resources Information Center

    Adamson, H. D.

    This paper attempts to show the relationship between variable rules and more widely used psycholinguistic constructs such as amalgams and schemas, and to point out how variationists' methods can be useful in the study of language acquisition. The traditional rule, the rule for forming the past tense of regular verbs in English, is discussed as it…

  19. A robotically constructed production and supply base on Phobos

    NASA Astrophysics Data System (ADS)

    1989-05-01

    PHOBIA Corporation is involved with the design of a man-tenable robotically constructed, bootstrap base on Mars' moon, Phobos. This base will be a pit-stop for future manned missions to Mars and beyond and will be a control facility during the robotic construction of a Martian base. An introduction is given to the concepts and the ground rules followed during the design process. Details of a base design and its location are given along with information about some of the subsystems. Since a major purpose of the base is to supply fuel to spacecraft so they can limit their fuel mass, mining and production systems are discussed. Surface support activities such as docks, anchors, and surface transportation systems are detailed. Several power supplies for the base are investigated and include fuel cells and a nuclear reactor. Tasks for the robots are defined along with descriptions of the robots capable of completing the tasks. Finally, failure modes for the entire PHOBIA Corporation design are presented along with an effects analysis and preventative recommendations.

  20. A robotically constructed production and supply base on Phobos

    NASA Technical Reports Server (NTRS)

    1989-01-01

    PHOBIA Corporation is involved with the design of a man-tenable robotically constructed, bootstrap base on Mars' moon, Phobos. This base will be a pit-stop for future manned missions to Mars and beyond and will be a control facility during the robotic construction of a Martian base. An introduction is given to the concepts and the ground rules followed during the design process. Details of a base design and its location are given along with information about some of the subsystems. Since a major purpose of the base is to supply fuel to spacecraft so they can limit their fuel mass, mining and production systems are discussed. Surface support activities such as docks, anchors, and surface transportation systems are detailed. Several power supplies for the base are investigated and include fuel cells and a nuclear reactor. Tasks for the robots are defined along with descriptions of the robots capable of completing the tasks. Finally, failure modes for the entire PHOBIA Corporation design are presented along with an effects analysis and preventative recommendations.

  1. Major Clades of Australasian Rutoideae (Rutaceae) Based on rbcL and atpB Sequences

    PubMed Central

    Bayly, Michael J.; Holmes, Gareth D.; Forster, Paul I.; Cantrill, David J.; Ladiges, Pauline Y.

    2013-01-01

    Background Rutaceae subfamily Rutoideae (46 genera, c. 660 species) is diverse in both rainforests and sclerophyll vegetation of Australasia. Australia and New Caledonia are centres of endemism with a number of genera and species distributed disjunctly between the two regions. Our aim was to generate a high-level molecular phylogeny for the Australasian Rutoideae and identify major clades as a framework for assessing morphological and biogeographic patterns and taxonomy. Methodology/Principal Findings Phylogenetic analyses were based on chloroplast genes, rbcL and atpB, for 108 samples (78 new here), including 38 of 46 Australasian genera. Results were integrated with those from other molecular studies to produce a supertree for Rutaceae worldwide, including 115 of 154 genera. Australasian clades are poorly matched with existing tribal classifications, and genera Philotheca and Boronia are not monophyletic. Major sclerophyll lineages in Australia belong to two separate clades, each with an early divergence between rainforest and sclerophyll taxa. Dehiscent fruits with seeds ejected at maturity (often associated with myrmecochory) are inferred as ancestral; derived states include woody capsules with winged seeds, samaras, fleshy drupes, and retention and display of seeds in dehisced fruits (the last two states adaptations to bird dispersal, with multiple origins among rainforest genera). Patterns of relationship and levels of sequence divergence in some taxa, mostly species, with bird-dispersed (Acronychia, Sarcomelicope, Halfordia and Melicope) or winged (Flindersia) seeds are consistent with recent long-distance dispersal between Australia and New Caledonia. Other deeper Australian/New Caledonian divergences, some involving ant-dispersed taxa (e.g., Neoschmidia), suggest older vicariance. Conclusions/Significance This comprehensive molecular phylogeny of the Australasian Rutoideae gives a broad overview of the group’s evolutionary and biogeographic history. Deficiencies of infrafamilial classifications of Rutoideae have long been recognised, and our results provide a basis for taxonomic revision and a necessary framework for more focused studies of genera and species. PMID:23967311

  2. 76 FR 38747 - Review of New Sources and Modifications in Indian Country

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ...The EPA is finalizing a Federal Implementation Plan (FIP) under the Clean Air Act (CAA or Act) for Indian country. The FIP includes two New Source Review (NSR) regulations for the protection of air resources in Indian country. The first rule applies to new and modified minor stationary sources (minor sources) and to minor modifications at existing major stationary sources (major sources) throughout Indian country. The second rule (nonattainment major NSR rule) applies to new and modified major sources in areas of Indian country that are designated as not attaining the National Ambient Air Quality Standards (NAAQS). These rules will be implemented by EPA or a delegate Tribal agency assisting EPA with administration of the rules, until replaced by an EPA-approved implementation plan.

  3. Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway.

    PubMed

    Wadas, Brandon; Borjigin, Jimo; Huang, Zheping; Oh, Jang-Hyun; Hwang, Cheol-Sang; Varshavsky, Alexander

    2016-08-12

    Serotonin N-acetyltransferase (AANAT) converts serotonin to N-acetylserotonin (NAS), a distinct biological regulator and the immediate precursor of melatonin, a circulating hormone that influences circadian processes, including sleep. N-terminal sequences of AANAT enzymes vary among vertebrates. Mechanisms that regulate the levels of AANAT are incompletely understood. Previous findings were consistent with the possibility that AANAT may be controlled through its degradation by the N-end rule pathway. By expressing the rat and human AANATs and their mutants not only in mammalian cells but also in the yeast Saccharomyces cerevisiae, and by taking advantage of yeast genetics, we show here that two "complementary" forms of rat AANAT are targeted for degradation by two "complementary" branches of the N-end rule pathway. Specifically, the N(α)-terminally acetylated (Nt-acetylated) Ac-AANAT is destroyed through the recognition of its Nt-acetylated N-terminal Met residue by the Ac/N-end rule pathway, whereas the non-Nt-acetylated AANAT is targeted by the Arg/N-end rule pathway, which recognizes the unacetylated N-terminal Met-Leu sequence of rat AANAT. We also show, by constructing lysine-to-arginine mutants of rat AANAT, that its degradation is mediated by polyubiquitylation of its Lys residue(s). Human AANAT, whose N-terminal sequence differs from that of rodent AANATs, is longer-lived than its rat counterpart and appears to be refractory to degradation by the N-end rule pathway. Together, these and related results indicate both a major involvement of the N-end rule pathway in the control of rodent AANATs and substantial differences in the regulation of rodent and human AANATs that stem from differences in their N-terminal sequences. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  4. 18 CFR 1.101 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Definitions. 1.101 Section 1.101 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES OF GENERAL APPLICABILITY Definitions and Rules of Construction § 1.101...

  5. 18 CFR 1.101 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Definitions. 1.101 Section 1.101 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES OF GENERAL APPLICABILITY Definitions and Rules of Construction § 1.101...

  6. 18 CFR 1.101 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Definitions. 1.101 Section 1.101 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES OF GENERAL APPLICABILITY Definitions and Rules of Construction § 1.101...

  7. 18 CFR 1.101 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Definitions. 1.101 Section 1.101 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES OF GENERAL APPLICABILITY Definitions and Rules of Construction § 1.101...

  8. 18 CFR 1.101 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Definitions. 1.101 Section 1.101 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES OF GENERAL APPLICABILITY Definitions and Rules of Construction § 1.101...

  9. A multilayer perceptron solution to the match phase problem in rule-based artificial intelligence systems

    NASA Technical Reports Server (NTRS)

    Sartori, Michael A.; Passino, Kevin M.; Antsaklis, Panos J.

    1992-01-01

    In rule-based AI planning, expert, and learning systems, it is often the case that the left-hand-sides of the rules must be repeatedly compared to the contents of some 'working memory'. The traditional approach to solve such a 'match phase problem' for production systems is to use the Rete Match Algorithm. Here, a new technique using a multilayer perceptron, a particular artificial neural network model, is presented to solve the match phase problem for rule-based AI systems. A syntax for premise formulas (i.e., the left-hand-sides of the rules) is defined, and working memory is specified. From this, it is shown how to construct a multilayer perceptron that finds all of the rules which can be executed for the current situation in working memory. The complexity of the constructed multilayer perceptron is derived in terms of the maximum number of nodes and the required number of layers. A method for reducing the number of layers to at most three is also presented.

  10. [Professor B. Jigmed's conception on the division of stages of history of Mongolian medicine].

    PubMed

    Wang, X H; Bao, L

    2017-03-28

    The division of stages on the formation and development of Mongolian medicine is a major issue on the history of Mongolian medicine. Based on Mongolian social, economic and cultural development and the characteristics of Mongolian medicine itself, Professor B. Jigmed creatively puts forward the three stages of development of ancient and modern times of Mongolian medicine. He also reasonably sorts out historical materials to comprehensively and systematically display the general picture of its development. This approach exerts great effect on restructuring the body of Mongolian medicine itself, unveils its rule of development, and promotes its disciplinary construction.

  11. Formalized description and construction of semantic dictionary of graphic-text spatial relationship

    NASA Astrophysics Data System (ADS)

    Sun, Yizhong; Xue, Xiaolei; Zhao, Xiaoqin

    2008-10-01

    Graphic and text are two major elements in exhibiting of the results of urban planning and land administration. In combination, they convey the complex relationship resulting from spatial analysis and decision-making. Accurately interpreting and representing these relationships are important steps towards an intelligent GIS for urban planning. This paper employs concept-hierarchy-tree to formalize graphic-text relationships through a framework of spatial object lexicon, spatial relationship lexicon, restriction lexicon, applied pattern base, and word segmentation rule base. The methodology is further verified and shown effective on several urban planning archives.

  12. Ensemble learning with trees and rules: supervised, semi-supervised, unsupervised

    USDA-ARS?s Scientific Manuscript database

    In this article, we propose several new approaches for post processing a large ensemble of conjunctive rules for supervised and semi-supervised learning problems. We show with various examples that for high dimensional regression problems the models constructed by the post processing the rules with ...

  13. 76 FR 50667 - Regulated Navigation Area; Portsmouth Naval Shipyard, Portsmouth, NH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-16

    ... provide for the safety of life on the navigable waters during ongoing ship construction. DATES: This rule.... ACTION: Temporary final rule. SUMMARY: The Coast Guard is establishing a regulated navigation area on the Piscataqua River near Portsmouth, NH. This temporary final rule places speed restrictions on all vessels...

  14. 78 FR 65932 - Updating OSHA Standards Based on National Consensus Standards; Signage

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ...; Signage AGENCY: Occupational Safety and Health Administration (OSHA), Department of Labor. ACTION... accompanied its direct final rule revising its signage standards for general industry and construction. DATES... proposed rule (NPRM) along with the direct final rule (DFR) (see 78 FR 35585) updating its signage...

  15. The Equilibrium Rule--A Personal Discovery

    ERIC Educational Resources Information Center

    Hewitt, Paul G.

    2016-01-01

    Examples of equilibrium are evident everywhere and the equilibrium rule provides a reasoned way to view all things, whether in static (balancing rocks, steel beams in building construction) or dynamic (airplanes, bowling balls) equilibrium. Interestingly, the equilibrium rule applies not just to objects at rest but whenever any object or system of…

  16. 76 FR 71465 - Defense Federal Acquisition Regulation Supplement: Management of Manufacturing Risk in Major...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ... Government procurement. Mary Overstreet, Editor, Defense Acquisition Regulations System. Interim Rule Adopted... Federal Acquisition Regulation Supplement: Management of Manufacturing Risk in Major Defense Acquisition...). ACTION: Final rule. SUMMARY: DoD is adopting as final, without change, an interim rule amending the...

  17. Montana SIP: Table c, (viii) Administrative Rules of Montana, Subchapter 10, Preconstruction Permit Requirements for Major Stationary Sources or Major Modifications Locating Within Attainment or Unclassified Areas

    EPA Pesticide Factsheets

    Montana SIP: Table c, (viii) Administrative Rules of Montana, Subchapter 10, Preconstruction Permit Requirements for Major Stationary Sources or Major Modifications Locating Within Attainment or Unclassified Areas

  18. New analytic results for speciation times in neutral models.

    PubMed

    Gernhard, Tanja

    2008-05-01

    In this paper, we investigate the standard Yule model, and a recently studied model of speciation and extinction, the "critical branching process." We develop an analytic way-as opposed to the common simulation approach-for calculating the speciation times in a reconstructed phylogenetic tree. Simple expressions for the density and the moments of the speciation times are obtained. Methods for dating a speciation event become valuable, if for the reconstructed phylogenetic trees, no time scale is available. A missing time scale could be due to supertree methods, morphological data, or molecular data which violates the molecular clock. Our analytic approach is, in particular, useful for the model with extinction, since simulations of birth-death processes which are conditioned on obtaining n extant species today are quite delicate. Further, simulations are very time consuming for big n under both models.

  19. Controllable phase transitions and novel selection rules in Josephson junctions with inherent orthogonality

    NASA Astrophysics Data System (ADS)

    Cheng, Qiang; Zhang, Kunhua; Ma, Hongyang

    2018-03-01

    We propose a new type of Josephson junction consisting of topologically nontrivial superconductors with inherent orthogonality and a ferromagnetic interface. It is found this type of junction can host rich ground states: 0 phase, π phase, 0 + π phase, φ0 phase and φ0 ± φ phase. Phase transitions can be controlled by changing the direction of the interfacial magnetization. Phase diagrams are presented in the orientation space. Novel selection rules for the lowest order current, sin ⁡ ϕ or cos ⁡ ϕ, of this kind of junction are derived. General conditions for the formation of various ground states are established, which possess guiding significance to the experimental design of required ground states for practical applications. We construct the succinct form of a Ginzburg-Landau type of free energy from the viewpoint of the interplay between topological superconductivity and ferromagnetism, which can immediately lead to the selection rules. The constructed terms are universally available to the topological Josephson junctions with or without inherent orthogonality reported recently. The spin supercurrent, its selection rules and their relations to the constructed energy are also investigated.

  20. Searching for the rules that govern hadron construction

    DOE PAGES

    Shepherd, Matthew R.; Dudek, Jozef J.; Mitchell, Ryan E.

    2016-06-22

    Just as quantum electrodynamics describes how electrons are bound in atoms by the electromagnetic force, mediated by the exchange of photons, quantum chromodynamics (QCD) describes how quarks are bound inside hadrons by the strong force, mediated by the exchange of gluons. QCD seems to allow hadrons constructed from increasingly many quarks to exist, just as atoms with increasing numbers of electrons exist, yet such complex constructions seemed, until recently, not to be present in nature. In this paper, we describe advances in the spectroscopy of mesons that are refining our understanding of the rules for predicting hadron structure from QCD.

  1. Modeling the effects of changes in new source review on national SO{sub 2} and NOx emissions from electricity-generating units

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David A. Evans; Benjamin F. Hobbs; Craig Oren

    2008-01-15

    The Clean Air Act establishes New Source Review (NSR) programs that apply to construction or modification of major stationary sources. In 2002 and 2003, EPA revised its rules to narrow NSR's coverage of renovations. Congress mandated a National Research Council study of the revisions' impacts. In that study, we used an electricity-sector model to explore possible effects of the equipment replacement provision (ERP), the principal NSR change directed at power plants. We find that, assuming implementation of the Clean Air Interstate Rule (CAIR), tight enforcement of the prerevision NSR rules would likely lead to no or limited decreases in nationalmore » emissions compared to policies such as ERP. However, emissions might shift forward in time because the previous NSR rules would depress allowance prices, discouraging banking and encouraging allowance use. Only under the most aggressive prerevision NSR enforcement scenario, in which essentially all coal capacity is compelled to retrofit controls by 2020, do NOx emissions fall below ERP levels. Even then, total 2007-2020 SO{sub 2} emissions are unaffected. Further decreases in national emissions could be accomplished more cheaply by tighter emissions caps than through NSR because caps provide incentives for efficient operating strategies, such as fuel switching, as well as retrofits. 23 refs., 2 figs., 1 tab.« less

  2. Accelerating population balance-Monte Carlo simulation for coagulation dynamics from the Markov jump model, stochastic algorithm and GPU parallel computing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, Zuwei; Zhao, Haibo, E-mail: klinsmannzhb@163.com; Zheng, Chuguang

    2015-01-15

    This paper proposes a comprehensive framework for accelerating population balance-Monte Carlo (PBMC) simulation of particle coagulation dynamics. By combining Markov jump model, weighted majorant kernel and GPU (graphics processing unit) parallel computing, a significant gain in computational efficiency is achieved. The Markov jump model constructs a coagulation-rule matrix of differentially-weighted simulation particles, so as to capture the time evolution of particle size distribution with low statistical noise over the full size range and as far as possible to reduce the number of time loopings. Here three coagulation rules are highlighted and it is found that constructing appropriate coagulation rule providesmore » a route to attain the compromise between accuracy and cost of PBMC methods. Further, in order to avoid double looping over all simulation particles when considering the two-particle events (typically, particle coagulation), the weighted majorant kernel is introduced to estimate the maximum coagulation rates being used for acceptance–rejection processes by single-looping over all particles, and meanwhile the mean time-step of coagulation event is estimated by summing the coagulation kernels of rejected and accepted particle pairs. The computational load of these fast differentially-weighted PBMC simulations (based on the Markov jump model) is reduced greatly to be proportional to the number of simulation particles in a zero-dimensional system (single cell). Finally, for a spatially inhomogeneous multi-dimensional (multi-cell) simulation, the proposed fast PBMC is performed in each cell, and multiple cells are parallel processed by multi-cores on a GPU that can implement the massively threaded data-parallel tasks to obtain remarkable speedup ratio (comparing with CPU computation, the speedup ratio of GPU parallel computing is as high as 200 in a case of 100 cells with 10 000 simulation particles per cell). These accelerating approaches of PBMC are demonstrated in a physically realistic Brownian coagulation case. The computational accuracy is validated with benchmark solution of discrete-sectional method. The simulation results show that the comprehensive approach can attain very favorable improvement in cost without sacrificing computational accuracy.« less

  3. Debate as Encapsulated Conflict: Ruled Controversy as an Approach to Learning Conflict Management Skills.

    ERIC Educational Resources Information Center

    Lee, David G.; Hensley, Carl Wayne

    Debate can provide a format for the development of communication skills to aid students in managing conflicts, because an understanding of rule-governed communication in conflict situations is invaluable in constructive conflict management. Since in debate procedural rules restrict discussion primarily to substantive and procedural topics, debate…

  4. Item-Writing Rules: Collective Wisdom

    ERIC Educational Resources Information Center

    Frey, B.B.; Petersen, S.; Edwards, L.M.; Pedrotti, J.T.; Peyton, V.

    2005-01-01

    In student assessment, teachers place the greatest weight on tests they have constructed themselves and have an equally great interest in the quality of those tests. To increase the validity of teacher-made tests, many item-writing rules-of-thumb are available in the literature, but few rules have been tested experimentally. In light of the…

  5. 28 CFR 32.4 - Terms; construction, severability; effect.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., DISABILITY, AND EDUCATIONAL ASSISTANCE BENEFIT CLAIMS General Provisions § 32.4 Terms; construction... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Terms; construction, severability; effect... indicate otherwise, the first three provisions of 1 U.S.C. 1 (rules of construction) shall apply. (b) If...

  6. 28 CFR 32.4 - Terms; construction, severability; effect.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., DISABILITY, AND EDUCATIONAL ASSISTANCE BENEFIT CLAIMS General Provisions § 32.4 Terms; construction... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Terms; construction, severability; effect... indicate otherwise, the first three provisions of 1 U.S.C. 1 (rules of construction) shall apply. (b) If...

  7. 28 CFR 32.4 - Terms; construction, severability; effect.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., DISABILITY, AND EDUCATIONAL ASSISTANCE BENEFIT CLAIMS General Provisions § 32.4 Terms; construction... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Terms; construction, severability; effect... indicate otherwise, the first three provisions of 1 U.S.C. 1 (rules of construction) shall apply. (b) If...

  8. 28 CFR 32.4 - Terms; construction, severability; effect.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., DISABILITY, AND EDUCATIONAL ASSISTANCE BENEFIT CLAIMS General Provisions § 32.4 Terms; construction... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Terms; construction, severability; effect... indicate otherwise, the first three provisions of 1 U.S.C. 1 (rules of construction) shall apply. (b) If...

  9. 75 FR 68305 - Proposed Rule Staying Numeric Limitation for the Construction and Development Point Source Category

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-05

    ... coverage and performing the following activities: Construction of buildings, including building, developing... Staying Numeric Limitation for the Construction and Development Point Source Category AGENCY... effluent limitation of 280 NTU and associated monitoring requirements for the Construction and Development...

  10. 40 CFR Appendix A to Subpart Bb of... - State Requirements Incorporated by Reference in Subpart BB of Part 147 of the Code of Federal...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... Construction-no conflict with board of land commissioners' authority. Section 82-11-105 through 82-11-110... Cuttings. Rule 36.22.1013. Filing of Completion Reports, Well Logs, Analyses, Reports, and Surveys. Rule 36.... Gas Oil Ratio Tests. Rule 36.22.1217. Water Production Report. Rule 36.22.1218. Gas to be Metered...

  11. 40 CFR Appendix A to Subpart Bb of... - State Requirements Incorporated by Reference in Subpart BB of Part 147 of the Code of Federal...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... Construction-no conflict with board of land commissioners' authority. Section 82-11-105 through 82-11-110... Cuttings. Rule 36.22.1013. Filing of Completion Reports, Well Logs, Analyses, Reports, and Surveys. Rule 36.... Gas Oil Ratio Tests. Rule 36.22.1217. Water Production Report. Rule 36.22.1218. Gas to be Metered...

  12. 40 CFR Appendix A to Subpart Bb of... - State Requirements Incorporated by Reference in Subpart BB of Part 147 of the Code of Federal...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... Construction-no conflict with board of land commissioners' authority. Section 82-11-105 through 82-11-110... Cuttings. Rule 36.22.1013. Filing of Completion Reports, Well Logs, Analyses, Reports, and Surveys. Rule 36.... Gas Oil Ratio Tests. Rule 36.22.1217. Water Production Report. Rule 36.22.1218. Gas to be Metered...

  13. 40 CFR Appendix A to Subpart Bb of... - State Requirements Incorporated by Reference in Subpart BB of Part 147 of the Code of Federal...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    .... Construction-no conflict with board of land commissioners' authority. Section 82-11-105 through 82-11-110... Cuttings. Rule 36.22.1013. Filing of Completion Reports, Well Logs, Analyses, Reports, and Surveys. Rule 36.... Gas Oil Ratio Tests. Rule 36.22.1217. Water Production Report. Rule 36.22.1218. Gas to be Metered...

  14. 40 CFR Appendix A to Subpart Bb of... - State Requirements Incorporated by Reference in Subpart BB of Part 147 of the Code of Federal...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... Construction-no conflict with board of land commissioners' authority. Section 82-11-105 through 82-11-110... Cuttings. Rule 36.22.1013. Filing of Completion Reports, Well Logs, Analyses, Reports, and Surveys. Rule 36.... Gas Oil Ratio Tests. Rule 36.22.1217. Water Production Report. Rule 36.22.1218. Gas to be Metered...

  15. The legal appearances of dementia in court rulings: mapping the terrain.

    PubMed

    Doron, Israel Issi; Werner, Perla; Spanier, Benny; Lazar, Ori

    2017-05-01

    Individuals with dementia may appear before the court in different roles: as victims, as witnesses, and as those standing up for their rights. While there is growing interest in the rights of older persons with dementia, relatively little empirical data exists regarding their actual interactions in courts. Therefore, the goal of this study was to empirically map this legal terrain. This study used a descriptive quantitative method. A computerized search of a national legal database limited to the period 2004-2014 and a screening process for the results were used to establish a sample of 280 court rulings that directly addressed dementia. All cases were analyzed and categorized into the following four criteria groups: characteristics of the person with dementia; characteristics of the legal procedure; the legal substance of the case; and the legal outcome. The majority of cases involved a single, very-elderly (i.e. over 80 years) woman, living in the community, with unspecified dementia. The majority of cases were heard and decided in lower level courts, addressing a broad range of primarily non-criminal legal issues. Finally, in the majority of non-criminal cases, the person with dementia was found to be legally capable, whereas in the majority of criminal cases, the person with dementia was found incapable. The legal needs and rights of persons with dementia are much broader than issues of legal capacity or social protection. Deeper knowledge and more research is needed in order to fully understand the contexts in which dementia is constructed under the law.

  16. Causation's nuclear future: applying proportional liability to the Price-Anderson Act.

    PubMed

    O'Connell, William D

    2014-11-01

    For more than a quarter century, public discourse has pushed the nuclear-power industry in the direction of heavier regulation and greater scrutiny, effectively halting construction of new reactors. By focusing on contemporary fear of significant accidents, such discourse begs the question of what the nation's court system would actually do should a major nuclear incident cause radiation-induced cancers. Congress's attempt to answer that question is the Price-Anderson Act, a broad statute addressing claims by the victims of a major nuclear accident. Lower courts interpreting the Act have repeatedly encountered a major stumbling block: it declares that judges must apply the antediluvian preponderance-of-the-evidence logic of state tort law, even though radiation science insists that the causes of radiation-induced cancers are more complex. After a major nuclear accident, the Act's paradoxically outdated rules for adjudicating "causation" would make post-incident compensation unworkable. This Note urges that nuclear-power-plant liability should not turn on eighteenth-century tort law. Drawing on modern scientific conclusions regarding the invariably "statistical" nature of cancer, this Note suggests a unitary federal standard for the Price-Anderson Act--that a defendant be deemed to have "caused" a plaintiff's injury in direct proportion to the increased risk of harm the defendant has imposed. This "proportional liability" rule would not only fairly evaluate the costs borne by injured plaintiffs and protect a reawakening nuclear industry from the prospect of bank-breaking litigation, but would prove workable with only minor changes to the Price-Anderson Act's standards of "injury" and "fault."

  17. Oil and Gas Stormwater Permitting Documents

    EPA Pesticide Factsheets

    This final rule exempts construction activities at oil and gas sites from the requirement to obtain an NPDES permit for stormwater discharges except in very limited instances. This rule is effective June 12, 2006.

  18. Study of market model describing the contrary behaviors of informed and uninformed agents: Being minority and being majority

    NASA Astrophysics Data System (ADS)

    Zhang, Yu-Xia; Liao, Hao; Medo, Matus; Shang, Ming-Sheng; Yeung, Chi Ho

    2016-05-01

    In this paper we analyze the contrary behaviors of the informed investors and uniformed investors, and then construct a competition model with two groups of agents, namely agents who intend to stay in minority and those who intend to stay in majority. We find two kinds of competitions, inter- and intra-groups. The model shows periodic fluctuation feature. The average distribution of strategies illustrates a prominent central peak which is relevant to the peak-fat-tail character of price change distribution in stock markets. Furthermore, in the modified model the tolerance time parameter makes the agents diversified. Finally, we compare the strategies distribution with the price change distribution in real stock market, and we conclude that contrary behavior rules and tolerance time parameter are indeed valid in the description of market model.

  19. 10 CFR 36.15 - Start of construction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Requirements § 36.15 Start of construction. The applicant may not begin construction of a new irradiator prior... work, purchase of a site, site surveys or soil testing, site preparation, site excavation, construction... license with respect to the requirements of the Atomic Energy Act of 1954, as amended, and rules...

  20. 75 FR 59933 - Specifications and Drawings for Construction of Direct Buried Plant

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... for Construction of Direct Buried Plant AGENCY: Rural Utilities Service, USDA. ACTION: Final rule..., Specifications and Drawings for Construction of Direct Buried Plant (Form 515a). The revised specifications will include new construction units for Fiber-to-the-Home, remove redundant or outdated requirements, and...

  1. The prefabricated building risk decision research of DM technology on the basis of Rough Set

    NASA Astrophysics Data System (ADS)

    Guo, Z. L.; Zhang, W. B.; Ma, L. H.

    2017-08-01

    With the resources crises and more serious pollution, the green building has been strongly advocated by most countries and become a new building style in the construction field. Compared with traditional building, the prefabricated building has its own irreplaceable advantages but is influenced by many uncertainties. So far, a majority of scholars have been studying based on qualitative researches from all of the word. This paper profoundly expounds its significance about the prefabricated building. On the premise of the existing research methods, combined with rough set theory, this paper redefines the factors which affect the prefabricated building risk. Moreover, it quantifies risk factors and establish an expert knowledge base through assessing. And then reduced risk factors about the redundant attributes and attribute values, finally form the simplest decision rule. This simplest decision rule, which is based on the DM technology of rough set theory, provides prefabricated building with a controllable new decision-making method.

  2. Predicting the planform configuration of the braided Toklat River, AK with a suite of rule-based models

    USGS Publications Warehouse

    Podolak, Charles J.

    2013-01-01

    An ensemble of rule-based models was constructed to assess possible future braided river planform configurations for the Toklat River in Denali National Park and Preserve, Alaska. This approach combined an analysis of large-scale influences on stability with several reduced-complexity models to produce the predictions at a practical level for managers concerned about the persistence of bank erosion while acknowledging the great uncertainty in any landscape prediction. First, a model of confluence angles reproduced observed angles of a major confluence, but showed limited susceptibility to a major rearrangement of the channel planform downstream. Second, a probabilistic map of channel locations was created with a two-parameter channel avulsion model. The predicted channel belt location was concentrated in the same area as the current channel belt. Finally, a suite of valley-scale channel and braid plain characteristics were extracted from a light detection and ranging (LiDAR)-derived surface. The characteristics demonstrated large-scale stabilizing topographic influences on channel planform. The combination of independent analyses increased confidence in the conclusion that the Toklat River braided planform is a dynamically stable system due to large and persistent valley-scale influences, and that a range of avulsive perturbations are likely to result in a relatively unchanged planform configuration in the short term.

  3. 49 CFR 193.2009 - Rules of regulatory construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 193.2009 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY LIQUEFIED NATURAL GAS FACILITIES: FEDERAL SAFETY STANDARDS General § 193.2009 Rules of regulatory...

  4. Quantum voting and violation of Arrow's impossibility theorem

    NASA Astrophysics Data System (ADS)

    Bao, Ning; Yunger Halpern, Nicole

    2017-06-01

    We propose a quantum voting system in the spirit of quantum games such as the quantum prisoner's dilemma. Our scheme enables a constitution to violate a quantum analog of Arrow's impossibility theorem. Arrow's theorem is a claim proved deductively in economics: Every (classical) constitution endowed with three innocuous-seeming properties is a dictatorship. We construct quantum analogs of constitutions, of the properties, and of Arrow's theorem. A quantum version of majority rule, we show, violates this quantum Arrow conjecture. Our voting system allows for tactical-voting strategies reliant on entanglement, interference, and superpositions. This contribution to quantum game theory helps elucidate how quantum phenomena can be harnessed for strategic advantage.

  5. 78 FR 40351 - Procedural Rule To Establish Supervisory Authority Over Certain Nonbank Covered Persons Based on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ...) Origination, brokerage, or servicing of loans secured by real estate for use by consumers primarily for... the construction of time limits, change of time limits, and effect of deadlines. Under the final rule... covered persons potentially subject to the final rule should not require additional time to come into...

  6. 27 CFR 53.96 - Constructive sale price; special rule for arm's-length sales.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...; special rule for arm's-length sales. 53.96 Section 53.96 Alcohol, Tobacco Products and Firearms ALCOHOL... sale price; special rule for arm's-length sales. (a) In general. Section 4216(b)(2) of the Code... distributors in arm's-length transactions, and the manufacturer establishes that its prices in such cases are...

  7. 27 CFR 53.96 - Constructive sale price; special rule for arm's-length sales.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...; special rule for arm's-length sales. 53.96 Section 53.96 Alcohol, Tobacco Products and Firearms ALCOHOL... sale price; special rule for arm's-length sales. (a) In general. Section 4216(b)(2) of the Code... distributors in arm's-length transactions, and the manufacturer establishes that its prices in such cases are...

  8. 27 CFR 53.96 - Constructive sale price; special rule for arm's-length sales.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...; special rule for arm's-length sales. 53.96 Section 53.96 Alcohol, Tobacco Products and Firearms ALCOHOL... sale price; special rule for arm's-length sales. (a) In general. Section 4216(b)(2) of the Code... distributors in arm's-length transactions, and the manufacturer establishes that its prices in such cases are...

  9. 27 CFR 53.96 - Constructive sale price; special rule for arm's-length sales.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...; special rule for arm's-length sales. 53.96 Section 53.96 Alcohol, Tobacco Products and Firearms ALCOHOL... sale price; special rule for arm's-length sales. (a) In general. Section 4216(b)(2) of the Code... distributors in arm's-length transactions, and the manufacturer establishes that its prices in such cases are...

  10. 12 CFR 1022.75 - Rules of construction.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... finance company only. The auto dealer has no duty to provide a risk-based pricing notice to the consumer. However, the bank or finance company may comply with this rule if the auto dealer has agreed to provide...

  11. 12 CFR 1022.75 - Rules of construction.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... finance company only. The auto dealer has no duty to provide a risk-based pricing notice to the consumer. However, the bank or finance company may comply with this rule if the auto dealer has agreed to provide...

  12. 12 CFR 1022.75 - Rules of construction.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... finance company only. The auto dealer has no duty to provide a risk-based pricing notice to the consumer. However, the bank or finance company may comply with this rule if the auto dealer has agreed to provide...

  13. Analysis of mesenchymal stem cell differentiation in vitro using classification association rule mining.

    PubMed

    Wang, Weiqi; Wang, Yanbo Justin; Bañares-Alcántara, René; Coenen, Frans; Cui, Zhanfeng

    2009-12-01

    In this paper, data mining is used to analyze the data on the differentiation of mammalian Mesenchymal Stem Cells (MSCs), aiming at discovering known and hidden rules governing MSC differentiation, following the establishment of a web-based public database containing experimental data on the MSC proliferation and differentiation. To this effect, a web-based public interactive database comprising the key parameters which influence the fate and destiny of mammalian MSCs has been constructed and analyzed using Classification Association Rule Mining (CARM) as a data-mining technique. The results show that the proposed approach is technically feasible and performs well with respect to the accuracy of (classification) prediction. Key rules mined from the constructed MSC database are consistent with experimental observations, indicating the validity of the method developed and the first step in the application of data mining to the study of MSCs.

  14. Creative Strategic Intelligence Analysis and Decision Making Within the Elements of National Power. Proteus Futures Workshop, held Carlise, PA on 14-16 Aug 2007

    DTIC Science & Technology

    2007-08-01

    Professor Ayers suggests the facts have been present since 1979 and the initiation of Khomeini’s objectives: Islamic Rule over Iran, expanding Islamic Rule ...Dajjal (Anti-Christ), establish Islam as the global religion, and rule the world for seven to nine years. True believers are to seek out martyrdom for...without the need for new rules and constructs. He uses the same rules and analysis that he applies to physical combat and pleads that we should stop

  15. Bayesian design of decision rules for failure detection

    NASA Technical Reports Server (NTRS)

    Chow, E. Y.; Willsky, A. S.

    1984-01-01

    The formulation of the decision making process of a failure detection algorithm as a Bayes sequential decision problem provides a simple conceptualization of the decision rule design problem. As the optimal Bayes rule is not computable, a methodology that is based on the Bayesian approach and aimed at a reduced computational requirement is developed for designing suboptimal rules. A numerical algorithm is constructed to facilitate the design and performance evaluation of these suboptimal rules. The result of applying this design methodology to an example shows that this approach is potentially a useful one.

  16. Making Sense by Building Sense: Kindergarten Children's Construction and Understanding of Adaptive Robot Behaviors

    ERIC Educational Resources Information Center

    Mioduser, David; Levy, Sharona T.

    2010-01-01

    This study explores young children's ability to construct and explain adaptive behaviors of a behaving artifact, an autonomous mobile robot with sensors. A central component of the behavior construction environment is the RoboGan software that supports children's construction of spatiotemporal events with an a-temporal rule structure. Six…

  17. 76 FR 38552 - Amendments to Regulations Regarding Major Life-Changing Events Affecting Income-Related Monthly...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... to Regulations Regarding Major Life-Changing Events Affecting Income-Related Monthly Adjustment.... SUMMARY: This final rule adopts, without change, the interim final rule with request for comments we... consider major life-changing events for the Medicare Part B income- related monthly adjustment amount...

  18. 17 CFR 250.91 - Determination of cost.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction... amount of capital reasonably necessary for the performance of services or construction for, or the... service, sales, or construction contract. (c) Any expense (including the price paid for goods) incurred in...

  19. 18 CFR 401.124 - Construction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Construction. 401.124 Section 401.124 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE General Provisions § 401.124 Construction. This part is...

  20. 18 CFR 401.124 - Construction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Construction. 401.124 Section 401.124 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE General Provisions § 401.124 Construction. This part is...

  1. 18 CFR 401.124 - Construction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Construction. 401.124 Section 401.124 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE General Provisions § 401.124 Construction. This part is...

  2. 18 CFR 401.124 - Construction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Construction. 401.124 Section 401.124 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE General Provisions § 401.124 Construction. This part is...

  3. 26 CFR 1.23-3 - Special rules.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... conform to the plans or specifications of the completed building. For this purpose, construction includes... construction or reconstruction of a dwelling. In the case of renewable energy source expenditures in connection with the construction or reconstruction of a dwelling that becomes the taxpayer's new principal...

  4. 18 CFR 401.124 - Construction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Construction. 401.124 Section 401.124 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE General Provisions § 401.124 Construction. This part is...

  5. Performance evaluation of court in construction claims settlement of litigation

    NASA Astrophysics Data System (ADS)

    Hayati, Kemala; Latief, Yusuf; Rarasati, Ayomi Dita; Siddik, Arief

    2017-06-01

    Claim construction has a major influence on the implementation of projects, such as the cost and time. The success of the construction project is highly dependent on the effective resolution of claims. Although it has been recognized that litigation or court is not the best way because it may reduce or eliminate profits and damage the relationship, it is a method of resolving claims and disputes that is common in the world of construction. The method of resolving claims and disputes through litigation or court may solve the problem in an alternative method, namely the implementation of the judgment which can be enforced effectively against the losing party and the ruling which has the force of law of the country where the claims and disputes are examined. However, litigation or court may take longer time and require high cost. Thus, it is necessary to identify factors affecting the performance of the court and to develop a system capable of improving an existing system in order to run more effectively and efficiently. Resolution in the claims management of construction projects with the method of litigation is a procedure that can be used by the courts in order to shorten the time in order to reduce the cost. The scope of this research is directed to all parties involved in the construction, both the owners and the contractors as implementers and practitioners, as well as experts who are experienced in construction law.

  6. Nanoparticle Superlattice Engineering with DNA

    NASA Astrophysics Data System (ADS)

    Mirkin, Chad

    2012-02-01

    Recent developments in strategies for assembling nanomaterials have allowed us to draw a direct analogy between the assembly of solid state atomic lattices and the construction of nanoparticle superlattices. Herein, we present a set of six design rules for using DNA as a programmable linker to deliberately stabilize nine distinct colloidal crystal structures, with lattice parameters that are tailorable over the 25-150 nm size regime. These rules are analogous to those put forth by Pauling decades ago to explain the relative stability of lattices composed of atoms and small molecules. It is ideal to use DNA as a nanoscale bond to connect nanoparticles to achieve colloidal superlattice structures in this system, since its programmable nature allows for facile control over nanoparticle bond length and strength, and nanoparticle bond selectivity. This assembly method affords simultaneous and independent control over nanoparticle structure, crystallographic symmetry, and lattice parameters with nanometer scale precision. Further, we have developed a phase diagram that predicts the design parameters necessary to achieve a lattice with a given symmetry and lattice parameters a priori. The rules developed in this work present a major advance towards true materials by design, as they effectively separate the identity of a particle core (and thereby its physical properties) from the variables that control its assembly.

  7. 26 CFR 148.1-5 - Constructive sale price.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 17 2010-04-01 2010-04-01 false Constructive sale price. 148.1-5 Section 148.1... § 148.1-5 Constructive sale price. (a) Purpose of this section. The purpose of this section is to set forth temporary rules to be used in determining a constructive sale price under section 4216(b) of the...

  8. 33 CFR 86.23 - Construction.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Construction. 86.23 Section 86.23 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INLAND NAVIGATION RULES ANNEX III: TECHNICAL DETAILS OF SOUND SIGNAL APPLIANCES Bell or Gong § 86.23 Construction. Bells and gongs...

  9. 33 CFR 86.23 - Construction.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Construction. 86.23 Section 86.23 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INLAND NAVIGATION RULES ANNEX III: TECHNICAL DETAILS OF SOUND SIGNAL APPLIANCES Bell or Gong § 86.23 Construction. Bells and gongs...

  10. 43 CFR 4.1102 - Construction.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Construction. 4.1102 Section 4.1102 Public Lands: Interior Office of the Secretary of the Interior DEPARTMENT HEARINGS AND APPEALS PROCEDURES... Construction. These rules shall be construed to achieve the just, timely, and inexpensive determination of all...

  11. 33 CFR 86.23 - Construction.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Construction. 86.23 Section 86.23 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INLAND NAVIGATION RULES ANNEX III: TECHNICAL DETAILS OF SOUND SIGNAL APPLIANCES Bell or Gong § 86.23 Construction. Bells and gongs...

  12. 33 CFR 86.23 - Construction.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Construction. 86.23 Section 86.23 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INLAND NAVIGATION RULES ANNEX III: TECHNICAL DETAILS OF SOUND SIGNAL APPLIANCES Bell or Gong § 86.23 Construction. Bells and gongs...

  13. 33 CFR 86.23 - Construction.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Construction. 86.23 Section 86.23 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INLAND NAVIGATION RULES ANNEX III: TECHNICAL DETAILS OF SOUND SIGNAL APPLIANCES Bell or Gong § 86.23 Construction. Bells and gongs...

  14. 43 CFR 4.1102 - Construction.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Construction. 4.1102 Section 4.1102 Public Lands: Interior Office of the Secretary of the Interior DEPARTMENT HEARINGS AND APPEALS PROCEDURES... Construction. These rules shall be construed to achieve the just, timely, and inexpensive determination of all...

  15. 43 CFR 4.1102 - Construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Construction. 4.1102 Section 4.1102 Public Lands: Interior Office of the Secretary of the Interior DEPARTMENT HEARINGS AND APPEALS PROCEDURES... Construction. These rules shall be construed to achieve the just, timely, and inexpensive determination of all...

  16. 43 CFR 4.1102 - Construction.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Construction. 4.1102 Section 4.1102 Public Lands: Interior Office of the Secretary of the Interior DEPARTMENT HEARINGS AND APPEALS PROCEDURES... Construction. These rules shall be construed to achieve the just, timely, and inexpensive determination of all...

  17. 43 CFR 4.1102 - Construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Construction. 4.1102 Section 4.1102 Public Lands: Interior Office of the Secretary of the Interior DEPARTMENT HEARINGS AND APPEALS PROCEDURES... Construction. These rules shall be construed to achieve the just, timely, and inexpensive determination of all...

  18. 40 CFR 52.736 - Review of new sources and modifications.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sources and modifications. (a) [Reserved] (b) The rules submitted by the State on March 24, 1988, to... Sources Construction and Modification as effective March 22, 1991. The moratorium on construction and...

  19. 77 FR 49722 - Cranes and Derricks in Construction: Demolition and Underground Construction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... cranes rule, OSHA prepared a final economic analysis (FEA) as required by the Occupational Safety and... construction work involving demolition. The FEA for the final cranes standard, which included all cranes, crane... were technologically and economically feasible. Because the FEA drew these conclusions from...

  20. 7 CFR 1786.151 - Definitions and rules of construction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... part. Business day means any day on which both the RUS and the Federal Reserve Bank of New York are open for business. Construction Fund Account means the Cash—Construction Fund—Trustee Account... Prepayment agreement. Closing date shall mean any business day identified as such by the Government in its...

  1. 12 CFR 747.12 - Construction of time limits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Construction of time limits. 747.12 Section 747.12 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS... of Practice and Procedure § 747.12 Construction of time limits. (a) General rule. In computing any...

  2. 77 FR 18990 - Approval and Promulgation of Implementation Plans; New Mexico; Construction Permit Fees

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... reviewing and acting on specific air quality construction permit applications received by the New Mexico... Promulgation of Implementation Plans; New Mexico; Construction Permit Fees AGENCY: Environmental Protection... replace existing rules, and revisions to the applicable State Implementation Plan (SIP) for New Mexico...

  3. 17 CFR 250.90 - Transactions limited to cost.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction... service or construction for, or sell any goods to, any associate company thereof which is a public utility... construction for, or selling goods to, associate public utility companies, or enter into any contract to do so...

  4. 26 CFR 1.168(k)-1 - Additional first year depreciation deduction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... section) that is entered into prior to the manufacture, construction, or production of the property for... manufacture, construction, or production of this property begins after December 31, 2004, the acquisition rule..., construction, or production begin—(1) In general. For purposes of paragraph (b)(4)(iii) of this section...

  5. 26 CFR 1.168(k)-1 - Additional first year depreciation deduction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... section) that is entered into prior to the manufacture, construction, or production of the property for... manufacture, construction, or production of this property begins after December 31, 2004, the acquisition rule..., construction, or production begin—(1) In general. For purposes of paragraph (b)(4)(iii) of this section...

  6. 26 CFR 1.168(k)-1 - Additional first year depreciation deduction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... section) that is entered into prior to the manufacture, construction, or production of the property for... manufacture, construction, or production of this property begins after December 31, 2004, the acquisition rule..., construction, or production begin—(1) In general. For purposes of paragraph (b)(4)(iii) of this section...

  7. 76 FR 42545 - Regulated Navigation Area; Chelsea Street Bridge Construction, Chelsea, MA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ...-AA11 Regulated Navigation Area; Chelsea Street Bridge Construction, Chelsea, MA AGENCY: Coast Guard... and surrounding the Chelsea Street Bridge (CSB) that crosses the Chelsea River between East Boston and... navigable waters during the construction of the Chelsea Street Bridge. DATES: This rule is effective in the...

  8. 75 FR 38923 - Regulated Navigation Area: Niantic Railroad Bridge Construction, Niantic, CT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ...-AA11 Regulated Navigation Area: Niantic Railroad Bridge Construction, Niantic, CT AGENCY: Coast Guard... Niantic River Channel under and surrounding the Amtrak Railroad Bridge that crosses Niantic Bay in the... on the navigable waters during the construction of the Niantic Railroad Bridge. DATES: This rule is...

  9. 76 FR 21851 - Defense Federal Acquisition Regulation Supplement; Construction and Architect-Engineer Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-19

    ... data on DD Form 2626, Performance Evaluation (Construction), and DD Form 2631, Performance Evaluation...(e) for the requirements for preparing past performance evaluations. The objective of this rule is to remove the requirement to use DD Forms 2626, Performance Evaluation (Construction), and 2631, Performance...

  10. A rule-based software test data generator

    NASA Technical Reports Server (NTRS)

    Deason, William H.; Brown, David B.; Chang, Kai-Hsiung; Cross, James H., II

    1991-01-01

    Rule-based software test data generation is proposed as an alternative to either path/predicate analysis or random data generation. A prototype rule-based test data generator for Ada programs is constructed and compared to a random test data generator. Four Ada procedures are used in the comparison. Approximately 2000 rule-based test cases and 100,000 randomly generated test cases are automatically generated and executed. The success of the two methods is compared using standard coverage metrics. Simple statistical tests showing that even the primitive rule-based test data generation prototype is significantly better than random data generation are performed. This result demonstrates that rule-based test data generation is feasible and shows great promise in assisting test engineers, especially when the rule base is developed further.

  11. GDRMS: a system for automatic extraction of the disease-centre relation

    NASA Astrophysics Data System (ADS)

    Yang, Ronggen; Zhang, Yue; Gong, Lejun

    2012-01-01

    With the rapidly increasing of biomedical literature, the deluge of new articles is leading to information overload. Extracting the available knowledge from the huge amount of biomedical literature has become a major challenge. GDRMS is developed as a tool that extracts the relationship between disease and gene, gene and gene from biomedical literatures using text mining technology. It is a ruled-based system which also provides disease-centre network visualization, constructs the disease-gene database, and represents a gene engine for understanding the function of the gene. The main focus of GDRMS is to provide a valuable opportunity to explore the relationship between disease and gene for the research community about etiology of disease.

  12. Algorithmic commonalities in the parallel environment

    NASA Technical Reports Server (NTRS)

    Mcanulty, Michael A.; Wainer, Michael S.

    1987-01-01

    The ultimate aim of this project was to analyze procedures from substantially different application areas to discover what is either common or peculiar in the process of conversion to the Massively Parallel Processor (MPP). Three areas were identified: molecular dynamic simulation, production systems (rule systems), and various graphics and vision algorithms. To date, only selected graphics procedures have been investigated. They are the most readily available, and produce the most visible results. These include simple polygon patch rendering, raycasting against a constructive solid geometric model, and stochastic or fractal based textured surface algorithms. Only the simplest of conversion strategies, mapping a major loop to the array, has been investigated so far. It is not entirely satisfactory.

  13. Traffic incident management in construction and maintenance work zones.

    DOT National Transportation Integrated Search

    2009-01-01

    In 2004, the Federal Highway Administration published updated rules governing work zone safety and mobility; all highway construction and maintenance projects using federal-aid highway funds are required to develop transportation management plans (TM...

  14. Personalization of Rule-based Web Services.

    PubMed

    Choi, Okkyung; Han, Sang Yong

    2008-04-04

    Nowadays Web users have clearly expressed their wishes to receive personalized services directly. Personalization is the way to tailor services directly to the immediate requirements of the user. However, the current Web Services System does not provide any features supporting this such as consideration of personalization of services and intelligent matchmaking. In this research a flexible, personalized Rule-based Web Services System to address these problems and to enable efficient search, discovery and construction across general Web documents and Semantic Web documents in a Web Services System is proposed. This system utilizes matchmaking among service requesters', service providers' and users' preferences using a Rule-based Search Method, and subsequently ranks search results. A prototype of efficient Web Services search and construction for the suggested system is developed based on the current work.

  15. Designing collective behavior in a termite-inspired robot construction team.

    PubMed

    Werfel, Justin; Petersen, Kirstin; Nagpal, Radhika

    2014-02-14

    Complex systems are characterized by many independent components whose low-level actions produce collective high-level results. Predicting high-level results given low-level rules is a key open challenge; the inverse problem, finding low-level rules that give specific outcomes, is in general still less understood. We present a multi-agent construction system inspired by mound-building termites, solving such an inverse problem. A user specifies a desired structure, and the system automatically generates low-level rules for independent climbing robots that guarantee production of that structure. Robots use only local sensing and coordinate their activity via the shared environment. We demonstrate the approach via a physical realization with three autonomous climbing robots limited to onboard sensing. This work advances the aim of engineering complex systems that achieve specific human-designed goals.

  16. Object Synthesis in Conway's Game of Life and Other Cellular Automata

    NASA Astrophysics Data System (ADS)

    Niemiec, Mark D.

    Of the very large number of cellular automata rules in existence, a relatively small number of rules may be considered interesting. Some of the features that make such rules interesting permit patterns to expand, contract, separate into multiple sub-patterns, or combine with other patterns. Such rules generally include still-lifes, oscillators, spaceships, spaceship guns, and puffer trains. Such structures can often be used to construct more complicated computational circuitry, and rules that contain them can often be shown to be computationally universal. Conway's Game of Life is one rule that has been well-studied for several decades, and has been shown to be very fruitful in this regard.

  17. Horizontal gene flow from Eubacteria to Archaebacteria and what it means for our understanding of eukaryogenesis.

    PubMed

    Akanni, Wasiu A; Siu-Ting, Karen; Creevey, Christopher J; McInerney, James O; Wilkinson, Mark; Foster, Peter G; Pisani, Davide

    2015-09-26

    The origin of the eukaryotic cell is considered one of the major evolutionary transitions in the history of life. Current evidence strongly supports a scenario of eukaryotic origin in which two prokaryotes, an archaebacterial host and an α-proteobacterium (the free-living ancestor of the mitochondrion), entered a stable symbiotic relationship. The establishment of this relationship was associated with a process of chimerization, whereby a large number of genes from the α-proteobacterial symbiont were transferred to the host nucleus. A general framework allowing the conceptualization of eukaryogenesis from a genomic perspective has long been lacking. Recent studies suggest that the origins of several archaebacterial phyla were coincident with massive imports of eubacterial genes. Although this does not indicate that these phyla originated through the same process that led to the origin of Eukaryota, it suggests that Archaebacteria might have had a general propensity to integrate into their genomes large amounts of eubacterial DNA. We suggest that this propensity provides a framework in which eukaryogenesis can be understood and studied in the light of archaebacterial ecology. We applied a recently developed supertree method to a genomic dataset composed of 392 eubacterial and 51 archaebacterial genera to test whether large numbers of genes flowing from Eubacteria are indeed coincident with the origin of major archaebacterial clades. In addition, we identified two potential large-scale transfers of uncertain directionality at the base of the archaebacterial tree. Our results are consistent with previous findings and seem to indicate that eubacterial gene imports (particularly from δ-Proteobacteria, Clostridia and Actinobacteria) were an important factor in archaebacterial history. Archaebacteria seem to have long relied on Eubacteria as a source of genetic diversity, and while the precise mechanism that allowed these imports is unknown, we suggest that our results support the view that processes comparable to those through which eukaryotes emerged might have been common in archaebacterial history. © 2015 The Author(s).

  18. Horizontal gene flow from Eubacteria to Archaebacteria and what it means for our understanding of eukaryogenesis

    PubMed Central

    Akanni, Wasiu A.; Siu-Ting, Karen; Creevey, Christopher J.; McInerney, James O.; Wilkinson, Mark; Foster, Peter G.; Pisani, Davide

    2015-01-01

    The origin of the eukaryotic cell is considered one of the major evolutionary transitions in the history of life. Current evidence strongly supports a scenario of eukaryotic origin in which two prokaryotes, an archaebacterial host and an α-proteobacterium (the free-living ancestor of the mitochondrion), entered a stable symbiotic relationship. The establishment of this relationship was associated with a process of chimerization, whereby a large number of genes from the α-proteobacterial symbiont were transferred to the host nucleus. A general framework allowing the conceptualization of eukaryogenesis from a genomic perspective has long been lacking. Recent studies suggest that the origins of several archaebacterial phyla were coincident with massive imports of eubacterial genes. Although this does not indicate that these phyla originated through the same process that led to the origin of Eukaryota, it suggests that Archaebacteria might have had a general propensity to integrate into their genomes large amounts of eubacterial DNA. We suggest that this propensity provides a framework in which eukaryogenesis can be understood and studied in the light of archaebacterial ecology. We applied a recently developed supertree method to a genomic dataset composed of 392 eubacterial and 51 archaebacterial genera to test whether large numbers of genes flowing from Eubacteria are indeed coincident with the origin of major archaebacterial clades. In addition, we identified two potential large-scale transfers of uncertain directionality at the base of the archaebacterial tree. Our results are consistent with previous findings and seem to indicate that eubacterial gene imports (particularly from δ-Proteobacteria, Clostridia and Actinobacteria) were an important factor in archaebacterial history. Archaebacteria seem to have long relied on Eubacteria as a source of genetic diversity, and while the precise mechanism that allowed these imports is unknown, we suggest that our results support the view that processes comparable to those through which eukaryotes emerged might have been common in archaebacterial history. PMID:26323767

  19. Assuring Structural Integrity in Army Systems

    DTIC Science & Technology

    1985-02-28

    power plants are* I. American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code , Section III - Rules for Construction of Nuclear...Power Plant Components; 2. ASNE Boiler and Pressure Vessel Code , Section XI, Rules for In-Service Inspection of Nuclear Power Plant Components; and 3

  20. Phylotranscriptomic analysis of the origin and early diversification of land plants

    PubMed Central

    Wickett, Norman J.; Mirarab, Siavash; Nguyen, Nam; Warnow, Tandy; Carpenter, Eric; Matasci, Naim; Ayyampalayam, Saravanaraj; Barker, Michael S.; Burleigh, J. Gordon; Gitzendanner, Matthew A.; Ruhfel, Brad R.; Wafula, Eric; Graham, Sean W.; Mathews, Sarah; Melkonian, Michael; Soltis, Douglas E.; Soltis, Pamela S.; Miles, Nicholas W.; Rothfels, Carl J.; Pokorny, Lisa; Shaw, A. Jonathan; DeGironimo, Lisa; Stevenson, Dennis W.; Surek, Barbara; Villarreal, Juan Carlos; Roure, Béatrice; Philippe, Hervé; dePamphilis, Claude W.; Chen, Tao; Deyholos, Michael K.; Baucom, Regina S.; Kutchan, Toni M.; Augustin, Megan M.; Wang, Jun; Zhang, Yong; Tian, Zhijian; Yan, Zhixiang; Wu, Xiaolei; Sun, Xiao; Wong, Gane Ka-Shu; Leebens-Mack, James

    2014-01-01

    Reconstructing the origin and evolution of land plants and their algal relatives is a fundamental problem in plant phylogenetics, and is essential for understanding how critical adaptations arose, including the embryo, vascular tissue, seeds, and flowers. Despite advances in molecular systematics, some hypotheses of relationships remain weakly resolved. Inferring deep phylogenies with bouts of rapid diversification can be problematic; however, genome-scale data should significantly increase the number of informative characters for analyses. Recent phylogenomic reconstructions focused on the major divergences of plants have resulted in promising but inconsistent results. One limitation is sparse taxon sampling, likely resulting from the difficulty and cost of data generation. To address this limitation, transcriptome data for 92 streptophyte taxa were generated and analyzed along with 11 published plant genome sequences. Phylogenetic reconstructions were conducted using up to 852 nuclear genes and 1,701,170 aligned sites. Sixty-nine analyses were performed to test the robustness of phylogenetic inferences to permutations of the data matrix or to phylogenetic method, including supermatrix, supertree, and coalescent-based approaches, maximum-likelihood and Bayesian methods, partitioned and unpartitioned analyses, and amino acid versus DNA alignments. Among other results, we find robust support for a sister-group relationship between land plants and one group of streptophyte green algae, the Zygnematophyceae. Strong and robust support for a clade comprising liverworts and mosses is inconsistent with a widely accepted view of early land plant evolution, and suggests that phylogenetic hypotheses used to understand the evolution of fundamental plant traits should be reevaluated. PMID:25355905

  1. The road surveying system of the federal highway research institute - a performance evaluation of road segmentation algorithms

    NASA Astrophysics Data System (ADS)

    Streiter, R.; Wanielik, G.

    2013-07-01

    The construction of highways and federal roadways is subject to many restrictions and designing rules. The focus is on safety, comfort and smooth driving. Unfortunately, the planning information for roadways and their real constitution, course and their number of lanes and lane widths is often unsure or not available. Due to digital map databases of roads raised much interest during the last years and became one major cornerstone of innovative Advanced Driving Assistance Systems (ADASs), the demand for accurate and detailed road information increases considerably. Within this project a measurement system for collecting high accurate road data was developed. This paper gives an overview about the sensor configuration within the measurement vehicle, introduces the implemented algorithms and shows some applications implemented in the post processing platform. The aim is to recover the origin parametric description of the roadway and the performance of the measurement system is being evaluated against several original road construction information.

  2. 75 FR 68429 - Cranes and Derricks in Construction; Approval of Information Collection Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-08

    .... OSHA-2007-0066] RIN 1218-AC01 Cranes and Derricks in Construction; Approval of Information Collection... requirements. SUMMARY: On August 9, 2010, OSHA published a final rule revising the Cranes and Derricks Standard... necessary to protect employees during the use of cranes and derricks in construction. That final standard...

  3. 75 FR 44282 - In the Matter of Certain Mobile Telephones and Wireless Communication Devices Featuring Digital...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ... review the June 22, 2010, initial determination on claim construction (``ID'') issued by the presiding... question of the legal authority for addressing the issue of claim construction as a matter for summary determination and treating the claim construction ruling as an initial determination under the Commission's...

  4. 26 CFR 1.1039-1 - Certain sales of low-income housing projects.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... considered as the purchase or construction by A of such a project. (2) Special rules. (i) The cost of a... capital expenditures by the taxpayer that are attributable to acquisition, construction, or reconstruction..., 1970. If the taxpayer had begun construction of another qualified housing project on January 1, 1969...

  5. 26 CFR 1.1039-1 - Certain sales of low-income housing projects.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... considered as the purchase or construction by A of such a project. (2) Special rules. (i) The cost of a... capital expenditures by the taxpayer that are attributable to acquisition, construction, or reconstruction..., 1970. If the taxpayer had begun construction of another qualified housing project on January 1, 1969...

  6. 77 FR 14276 - Regulated Navigation Area; Little Bay Bridge Construction, Little Bay, Portsmouth, NH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ...-AA11 Regulated Navigation Area; Little Bay Bridge Construction, Little Bay, Portsmouth, NH AGENCY... under and surrounding the Little Bay and General Sullivan Bridges in order to facilitate construction of the Little Bay Bridge between Newington, NH and Dover, NH. This temporary interim rule is necessary to...

  7. 40 CFR 62.13108 - Identification of plan.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Industrial Solid Waste Incineration Units. The State Plan includes revisions to Rule 102 and Rule 405 of the... Industrial Solid Waste Incineration Units for which construction commenced on or before November 30, 1999... Control of Air Emissions of Designated Pollutants from Existing Commercial and Industrial Solid Waste...

  8. Exploring novel key regulators in breast cancer network.

    PubMed

    Ali, Shahnawaz; Malik, Md Zubbair; Singh, Soibam Shyamchand; Chirom, Keilash; Ishrat, Romana; Singh, R K Brojen

    2018-01-01

    The breast cancer network constructed from 70 experimentally verified genes is found to follow hierarchical scale free nature with heterogeneous modular organization and diverge leading hubs. The topological parameters (degree distributions, clustering co-efficient, connectivity and centralities) of this network obey fractal rules indicating absence of centrality lethality rule, and efficient communication among the components. From the network theoretical approach, we identified few key regulators out of large number of leading hubs, which are deeply rooted from top to down of the network, serve as backbone of the network, and possible target genes. However, p53, which is one of these key regulators, is found to be in low rank and keep itself at low profile but directly cross-talks with important genes BRCA2 and BRCA3. The popularity of these hubs gets changed in unpredictable way at various levels of organization thus showing disassortive nature. The local community paradigm approach in this network shows strong correlation of nodes in majority of modules/sub-modules (fast communication among nodes) and weak correlation of nodes only in few modules/sub-modules (slow communication among nodes) at various levels of network organization.

  9. Measuring uncertainty by extracting fuzzy rules using rough sets and extracting fuzzy rules under uncertainty and measuring definability using rough sets

    NASA Technical Reports Server (NTRS)

    Worm, Jeffrey A.; Culas, Donald E.

    1991-01-01

    Computers are not designed to handle terms where uncertainty is present. To deal with uncertainty, techniques other than classical logic must be developed. This paper examines the concepts of statistical analysis, the Dempster-Shafer theory, rough set theory, and fuzzy set theory to solve this problem. The fundamentals of these theories are combined to provide the possible optimal solution. By incorporating principles from these theories, a decision-making process may be simulated by extracting two sets of fuzzy rules: certain rules and possible rules. From these rules a corresponding measure of how much we believe these rules is constructed. From this, the idea of how much a fuzzy diagnosis is definable in terms of its fuzzy attributes is studied.

  10. Regulatory impact analysis: benefits and costs of proposed surface water treatment rule and total coliform rule

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1987-09-01

    This report contains an analysis of the costs and benefits of controlling microbial contaminants in drinking water through the promulgation of two regulations: (1) the Surface Water Treatment Rule (SWTR); and (2) the Total Coliform Rule. This regulatory impact analysis (RIA) was prepared in accordance with Executive Order 12291, which requires that the costs and benefits of all major rules be examined and compared. The major topical areas covered in the RIA are as follows: problem definition; market imperfections, the need for federal regulation, and consideration of regulatory alternatives; assessment of total costs; assessment of benefits; regulatory flexibility act andmore » Paperwork Reduction Act analyses; and a summary of costs and benefits.« less

  11. Scale-free effect of substitution networks

    NASA Astrophysics Data System (ADS)

    Li, Ziyu; Yu, Zhouyu; Xi, Lifeng

    2018-02-01

    In this paper, we construct the growing networks in terms of substitution rule. Roughly speaking, we replace edges of different colors with different initial graphs. Then the evolving networks are constructed. We obtained the free-scale effect of our substitution networks.

  12. The U.S. Army and Doctrine for Weapons of Mass Destruction: Consequence Management Operations.

    DTIC Science & Technology

    1999-06-04

    Forces within section 7 Competency of witnesses 23 Construction Generally 1 With other laws 2 Estoppel 19 Exclusionary rule 22 Execution of laws 8...19. Estoppel Despite ruling in previous case that this section precluded prosecutions under section 231 of this title prohibiting attempts to

  13. 78 FR 46520 - Approval and Promulgation of Air Quality Implementation Plans; Wisconsin; Permit Exemption Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-01

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R05-OAR-2008-0402; FRL-9834-4] Approval and Promulgation of Air Quality Implementation Plans; Wisconsin; Permit Exemption Rule AGENCY: Environmental.... WDNR submitted revisions exempting certain sources of air pollution from construction permit...

  14. 46 CFR 174.355 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SUBDIVISION AND STABILITY SPECIAL RULES PERTAINING TO SPECIFIC VESSEL TYPES Special Rules Pertaining to Dry Cargo Ships § 174.355 Definitions. New ship means a... absence of a contract, the construction work of which is begun on or after August 1, 1992; or (iii) Which...

  15. 26 CFR 1.925(a)-1T - Temporary regulations; transfer pricing rules for FSCs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... paragraph. (D) Engineering or architectural services for construction projects located (or proposed for... this paragraph. (v) A special grouping rule applies to agricultural and horticultural products sold to... subdivision (i) of this paragraph does not apply. Income from the performance of engineering and architectural...

  16. Game Playing: Negotiating Rules and Identities

    ERIC Educational Resources Information Center

    Winther-Lindqvist, Ditte

    2009-01-01

    Beginning with Lev Vygotsky's long-established assertion that the play of children always involves both imaginary play and rules of behavior, this article argues for a theoretical framework that connects such play with the construction of social identities in kindergarten peer groups. It begins with a discussion of Ivy Schousboe's model of the…

  17. 10 CFR 501.9 - Effective date of orders or rules.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Effective date of orders or rules. 501.9 Section 501.9 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS ADMINISTRATIVE PROCEDURES AND SANCTIONS General... against construction without the capability of using coal or another alternate fuel, shall not take effect...

  18. Modeling the effects of changes in New Source Review on national SO{sub 2} and NOx emissions from electricity-generating units

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David A. Evans; Benjamin F. Hobbs; Craig Oren

    2007-03-15

    The Clean Air Act establishes New Source Review (NSR) programs that apply to the construction or modification of major stationary emissions sources. In 2002 and 2003, the U.S. Environmental Protection Agency revised its rules to narrow the applicability of NSR to facility renovations. Congress then mandated a National Research Council study of the effects of the rules. An electricity-sector model - the Integrated Planning Model (IPM) - was used to explore the possible effects of the equipment replacement provision (ERP), the principal NSR change that was to affect the power-generation industry. The studies focused in particular on coal-fired electricity generatingmore » units, EGUs, for two reasons. First, coal-fired EGUs are important contributors of these pollutants, accounting for approximately 70 and 20% of nations SO{sub 2} and NOx emissions in 2004, respectively. Second, the shares of total capacity of large coal-fired EGUs that lack flue-gas desulfurization to control SO{sub 2} and selective catalytic reduction to reduce NOx emissions are 62 and 63% respectively. Although the analysis cannot predict effects on local emissions, assuming that the Clean Air Interstate Rule (CAIR) is implemented, we find that stringent enforcement of the previous NSR rules would likely lead to no or limited decreases in national emissions compared to policies such as ERP. Our results indicate that tighter emissions caps could achieve further decreases in national emissions more cost-effectively than NSR programs. 15 refs., 3 figs., 1 tab.« less

  19. Ionic self-assembly for functional hierarchical nanostructured materials.

    PubMed

    Faul, Charl F J

    2014-12-16

    CONSPECTUS: The challenge of constructing soft functional materials over multiple length scales can be addressed by a number of different routes based on the principles of self-assembly, with the judicious use of various noncovalent interactions providing the tools to control such self-assembly processes. It is within the context of this challenge that we have extensively explored the use of an important approach for materials construction over the past decade: exploiting electrostatic interactions in our ionic self-assembly (ISA) method. In this approach, cooperative assembly of carefully chosen charged surfactants and oppositely charged building blocks (or tectons) provides a facile noncovalent route for the rational design and production of functional nanostructured materials. Generally, our research efforts have developed with an initial focus on establishing rules for the construction of novel noncovalent liquid-crystalline (LC) materials. We found that the use of double-tailed surfactant species (especially branched double-tailed surfactants) led to the facile formation of thermotropic (and, in certain cases, lyotropic) phases, as demonstrated by extensive temperature-dependent X-ray and light microscopy investigations. From this core area of activity, research expanded to cover issues beyond simple construction of anisotropic materials, turning to the challenge of inclusion and exploitation of switchable functionality. The use of photoactive azobenzene-containing ISA materials afforded opportunities to exploit both photo-orientation and surface relief grating formation. The preparation of these anisotropic LC materials was of interest, as the aim was the facile production of disposable and low-cost optical components for display applications and data storage. However, the prohibitive cost of the photo-orientation processes hampered further exploitation of these materials. We also expanded our activities to explore ISA of biologically relevant tectons, specifically deoxyguanosine monophosphate. This approach proved, in combination with block copolymer (BCP) self-assembly, very fruitful for the construction of complex and hierarchical functional materials across multiple length scales. Molecular frustration and incommensurability, which played a major role in structure formation in combination with nucleotide assembly, have now become important tools to tune supramolecular structure formation. These concepts, that is, the use of BCP assembly and incommensurability, in combination with metal-containing polymeric materials, have provided access to novel supramolecular morphologies and, more importantly, design rules to prepare such constructs. These design rules are now also being applied to the assembly of electroactive oligo(aniline)-based materials for the preparation of highly ordered functional soft materials, and present an opportunity for materials development for applications in energy storage. In this Account, we therefore discuss investigations into (i) the inclusion and preparation of supramolecular photoactive and electroactive materials; (ii) the exploitation and control over multiple noncovalent interactions to fine-tune function, internal structure, and long-range order and (iii) exploration of construction over multiple length scales by combination of ISA with well-known BCP self-assembly. Combination of ISA with tuning of volume fractions, mutual compatibility, and molecular frustration now provides a versatile tool kit to construct complex and hierarchical functional materials in a facile noncovalent way. A direct challenge for future ISA activities would certainly be the construction of functional mesoscale objects. However, within a broader scientific context, the challenge would be to exploit this powerful assembly tool for application in areas of research with societal impact, for example, energy storage and generation. The hope is that this Account will provide a platform for such future research activities and opportunities.

  20. A step-by-step introduction to rule-based design of synthetic genetic constructs using GenoCAD.

    PubMed

    Wilson, Mandy L; Hertzberg, Russell; Adam, Laura; Peccoud, Jean

    2011-01-01

    GenoCAD is an open source web-based system that provides a streamlined, rule-driven process for designing genetic sequences. GenoCAD provides a graphical interface that allows users to design sequences consistent with formalized design strategies specific to a domain, organization, or project. Design strategies include limited sets of user-defined parts and rules indicating how these parts are to be combined in genetic constructs. In addition to reducing design time to minutes, GenoCAD improves the quality and reliability of the finished sequence by ensuring that the designs follow established rules of sequence construction. GenoCAD.org is a publicly available instance of GenoCAD that can be found at www.genocad.org. The source code and latest build are available from SourceForge to allow advanced users to install and customize GenoCAD for their unique needs. This chapter focuses primarily on how the GenoCAD tools can be used to organize genetic parts into customized personal libraries, then how these libraries can be used to design sequences. In addition, GenoCAD's parts management system and search capabilities are described in detail. Instructions are provided for installing a local instance of GenoCAD on a server. Some of the future enhancements of this rapidly evolving suite of applications are briefly described. Copyright © 2011 Elsevier Inc. All rights reserved.

  1. 77 FR 55645 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to Construction and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... Incidental to Construction and Operation of a Liquefied Natural Gas Deepwater Port in the Gulf of Mexico... Incidental to Construction and Operation of a Liquefied Natural Gas Deepwater Port in the Gulf of Mexico...), Commerce. ACTION: Proposed rule; request for comments. SUMMARY: NMFS has received a request from Port...

  2. 78 FR 28547 - Approval and Promulgation of Air Quality Implementation Plans; Wisconsin; Permit Exemption Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ... each construction permit exemption claim. WDNR held public hearings on June 27, 28 and 29, 2006, for... required to respond to the construction permit exemption claim submitted. NR 406.04(1q)(1) and (5) for... pollution from construction permit requirements. EPA is proposing to approve these revisions because they...

  3. 78 FR 4365 - Capital, Margin, and Segregation Requirements for Security-Based Swap Dealers and Major Security...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... 3235-AL12 Capital, Margin, and Segregation Requirements for Security-Based Swap Dealers and Major... public comment to establish capital, margin, and segregation requirements for security-based swap dealers... soliciting comment on proposed rules and rule amendments establishing capital, margin, and segregation...

  4. Evolving rule-based systems in two medical domains using genetic programming.

    PubMed

    Tsakonas, Athanasios; Dounias, Georgios; Jantzen, Jan; Axer, Hubertus; Bjerregaard, Beth; von Keyserlingk, Diedrich Graf

    2004-11-01

    To demonstrate and compare the application of different genetic programming (GP) based intelligent methodologies for the construction of rule-based systems in two medical domains: the diagnosis of aphasia's subtypes and the classification of pap-smear examinations. Past data representing (a) successful diagnosis of aphasia's subtypes from collaborating medical experts through a free interview per patient, and (b) correctly classified smears (images of cells) by cyto-technologists, previously stained using the Papanicolaou method. Initially a hybrid approach is proposed, which combines standard genetic programming and heuristic hierarchical crisp rule-base construction. Then, genetic programming for the production of crisp rule based systems is attempted. Finally, another hybrid intelligent model is composed by a grammar driven genetic programming system for the generation of fuzzy rule-based systems. Results denote the effectiveness of the proposed systems, while they are also compared for their efficiency, accuracy and comprehensibility, to those of an inductive machine learning approach as well as to those of a standard genetic programming symbolic expression approach. The proposed GP-based intelligent methodologies are able to produce accurate and comprehensible results for medical experts performing competitive to other intelligent approaches. The aim of the authors was the production of accurate but also sensible decision rules that could potentially help medical doctors to extract conclusions, even at the expense of a higher classification score achievement.

  5. Auditing health insurance reimbursement by constructing association rules

    NASA Astrophysics Data System (ADS)

    Chiang, I.-Jen

    2000-04-01

    Two months of reimbursement claim data of the admission patients from National Taiwan University Hospital have been used to be the training set (200 MB or so), a quick method has been used to find out the association rules among the illness, the examinations and treatments, the drugs, and the equipment. The filtered rules by setting the minimum support and the minimum confidence are used to screen out a month claimed data from the other hospital. Some unproper orders to the patients are able to checked out. In this paper, we will discuss the algorithm for generalizing association rule and the experiments of using the association rules to screen out the unproper orders in the health reimbursement claims.

  6. Phase IV Land Disposal Restrictions Rule - Clarification of Effective Dates

    EPA Pesticide Factsheets

    Memo to clarify the effective dates for the major provisions of the Phase IV rule. It is supplemental to the final rule preamble at page 28556 (“Effective Dates”) and pages 28634-5 (“State Authority”).

  7. Idaho forestry best management practices: Compilation of research on their effectiveness

    Treesearch

    Kathleen A. Seyedbagheri

    1996-01-01

    A search was conducted for quantitative Idaho research results on the effectiveness of the Idaho Forest Practices Act rules and regulations pertaining to timber harvest and forest road construction and maintenance. These rules and regulations are designated as the "best management practices" for the prevention of nonpoint source pollution from silviculture...

  8. Applying the Rule Space Model to Develop a Learning Progression for Thermochemistry

    ERIC Educational Resources Information Center

    Chen, Fu; Zhang, Shanshan; Guo, Yanfang; Xin, Tao

    2017-01-01

    We used the Rule Space Model, a cognitive diagnostic model, to measure the learning progression for thermochemistry for senior high school students. We extracted five attributes and proposed their hierarchical relationships to model the construct of thermochemistry at four levels using a hypothesized learning progression. For this study, we…

  9. From Human Activity to Conceptual Understanding of the Chain Rule

    ERIC Educational Resources Information Center

    Jojo, Zingiswa Mybert Monica; Maharaj, Aneshkumar; Brijlall, Deonarain

    2013-01-01

    This article reports on a study which investigated first year university engineering students' construction of the definition of the concept of the chain rule in differential calculus at a University of Technology in South Africa. An APOS (Action-Process-Objects-Schema) approach was used to explore conceptual understanding displayed by students in…

  10. Wave Energy Prize - General Information

    DOE Data Explorer

    Scharmen, Wesley

    2016-12-01

    All the informational files, templates, rules and guidelines for Wave Energy Prize (WEP), including the Wave Energy Prize Rules, Participant Terms and Conditions Template, WEC Prize Name, Logo, Branding, WEC Publicity, Technical Submission Template , Numerical Modeling Template, SSTF Submission Template, 1/20th Scale Model Design and Construction Plan Template, Final Report template, and Webinars.

  11. Impact of Consciousness-Raising Activities on Young English Language Learners' Grammar Performance

    ERIC Educational Resources Information Center

    Fatemipour, Hamidreza; Hemmati, Shiva

    2015-01-01

    Grammar Consciousness-Raising (GCR) is an approach to teaching of grammar which learners instead of being taught the given rules, experience language data. The data challenge them to rethink, restructure their existing mental grammar and construct an explicit rule to describe the grammatical feature which the data illustrate (Ellis, 2002). And…

  12. Inconsistencies in Everyday Patterns of School Rules

    ERIC Educational Resources Information Center

    Thornberg, Robert

    2007-01-01

    The aim of this study is to investigate and explain inconsistencies within the social constructions of school rules as they take shape in everyday interactions between teachers and students, and to explore how students interpret these inconsistencies. An ethnographic study is conducted in two primary schools in Sweden. According to the findings,…

  13. 17 CFR 250.80 - Definitions of terms used in rules under section 13.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Definitions of terms used in..., Sales and Construction Contracts § 250.80 Definitions of terms used in rules under section 13. As used... context otherwise requires: (a) Service means any managerial, financial, legal, engineering, purchasing...

  14. 77 FR 34380 - Explorer Pipeline Company; Notice of Amendment to Petition for Declaratory Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-11

    ... Petition, Explorer described the Diluent Extension Project as involving the construction of a new pipeline..., pursuant to Rule 215 of the Commission's Rules of Practice and Procedure, 18 CFR 385.215 (2011), Explorer Pipeline Company (Explorer) filed an amendment to its March 23, 2012 Petition to the Federal Energy...

  15. Psychosocial Predictors of Rule Following in Hostels for Women Experiencing Homelessness

    ERIC Educational Resources Information Center

    White, Katherine; Wood, Maria

    2011-01-01

    This study examined the psychosocial factors impacting upon the rule-following behaviour of residents of a hostel providing crisis accommodation to women who are homeless. After their arrival, residents of a women's hostel (N=83) completed questionnaires assessing the theory of planned behaviour constructs of attitude, subjective norm, perceived…

  16. A Consistent Set of Oxidation Number Rules for Intelligent Computer Tutoring

    NASA Astrophysics Data System (ADS)

    Holder, Dale A.; Johnson, Benny G.; Karol, Paul J.

    2002-04-01

    We have developed a method for assigning oxidation numbers that eliminates the inconsistencies and ambiguities found in most conventional textbook rules, yet remains simple enough for beginning students to use. It involves imposition of a two-level hierarchy on a set of rules similar to those already being taught. We recommend emphasizing that the oxidation number method is an approximate model and cannot always be successfully applied. This proper perspective will lead students to apply the rules more carefully in all problems. Whenever failure does occur, it will indicate the limitations of the oxidation number concept itself, rather than merely the failure of a poorly constructed set of rules. We have used these improved rules as the basis for an intelligent tutoring program on oxidation numbers.

  17. Prediction of cancer class with majority voting genetic programming classifier using gene expression data.

    PubMed

    Paul, Topon Kumar; Iba, Hitoshi

    2009-01-01

    In order to get a better understanding of different types of cancers and to find the possible biomarkers for diseases, recently, many researchers are analyzing the gene expression data using various machine learning techniques. However, due to a very small number of training samples compared to the huge number of genes and class imbalance, most of these methods suffer from overfitting. In this paper, we present a majority voting genetic programming classifier (MVGPC) for the classification of microarray data. Instead of a single rule or a single set of rules, we evolve multiple rules with genetic programming (GP) and then apply those rules to test samples to determine their labels with majority voting technique. By performing experiments on four different public cancer data sets, including multiclass data sets, we have found that the test accuracies of MVGPC are better than those of other methods, including AdaBoost with GP. Moreover, some of the more frequently occurring genes in the classification rules are known to be associated with the types of cancers being studied in this paper.

  18. Rule-Based Design of Plant Expression Vectors Using GenoCAD.

    PubMed

    Coll, Anna; Wilson, Mandy L; Gruden, Kristina; Peccoud, Jean

    2015-01-01

    Plant synthetic biology requires software tools to assist on the design of complex multi-genic expression plasmids. Here a vector design strategy to express genes in plants is formalized and implemented as a grammar in GenoCAD, a Computer-Aided Design software for synthetic biology. It includes a library of plant biological parts organized in structural categories and a set of rules describing how to assemble these parts into large constructs. Rules developed here are organized and divided into three main subsections according to the aim of the final construct: protein localization studies, promoter analysis and protein-protein interaction experiments. The GenoCAD plant grammar guides the user through the design while allowing users to customize vectors according to their needs. Therefore the plant grammar implemented in GenoCAD will help plant biologists take advantage of methods from synthetic biology to design expression vectors supporting their research projects.

  19. Microbial genomic taxonomy

    PubMed Central

    2013-01-01

    A need for a genomic species definition is emerging from several independent studies worldwide. In this commentary paper, we discuss recent studies on the genomic taxonomy of diverse microbial groups and a unified species definition based on genomics. Accordingly, strains from the same microbial species share >95% Average Amino Acid Identity (AAI) and Average Nucleotide Identity (ANI), >95% identity based on multiple alignment genes, <10 in Karlin genomic signature, and > 70% in silico Genome-to-Genome Hybridization similarity (GGDH). Species of the same genus will form monophyletic groups on the basis of 16S rRNA gene sequences, Multilocus Sequence Analysis (MLSA) and supertree analysis. In addition to the established requirements for species descriptions, we propose that new taxa descriptions should also include at least a draft genome sequence of the type strain in order to obtain a clear outlook on the genomic landscape of the novel microbe. The application of the new genomic species definition put forward here will allow researchers to use genome sequences to define simultaneously coherent phenotypic and genomic groups. PMID:24365132

  20. Basic Helix-Loop-Helix Transcription Factor Gene Family Phylogenetics and Nomenclature

    PubMed Central

    Skinner, Michael K.; Rawls, Alan; Wilson-Rawls, Jeanne; Roalson, Eric H.

    2010-01-01

    A phylogenetic analysis of the basic helix-loop-helix (bHLH) gene superfamily was performed using seven different species (human, mouse, rat, worm, fly, yeast, and plant Arabidopsis) and involving over 600 bHLH genes [1]. All bHLH genes were identified in the genomes of the various species, including expressed sequence tags, and the entire coding sequence was used in the analysis. Nearly 15% of the gene family has been updated or added since the original publication. A super-tree involving six clades and all structural relationships was established and is now presented for four of the species. The wealth of functional data available for members of the bHLH gene superfamily provides us with the opportunity to use this exhaustive phylogenetic tree to predict potential functions of uncharacterized members of the family. This phylogenetic and genomic analysis of the bHLH gene family has revealed unique elements of the evolution and functional relationships of the different genes in the bHLH gene family. PMID:20219281

  1. 40 CFR 52.270 - Significant deterioration of air quality.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... applicable State plan for the State of California. (b) District PSD Plans. (1) The PSD rules for Sacramento... of PSD increments. (ii) Those projects which are major stationary sources or major modifications... 83-01, 5/6/83. (2) The PSD rules for North Coast Unified Air Quality Management District are approved...

  2. 40 CFR 52.270 - Significant deterioration of air quality.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... applicable State plan for the State of California. (b) District PSD Plans. (1) The PSD rules for Sacramento... of PSD increments. (ii) Those projects which are major stationary sources or major modifications... 83-01, 5/6/83. (2) The PSD rules for North Coast Unified Air Quality Management District are approved...

  3. 40 CFR 52.270 - Significant deterioration of air quality.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... applicable State plan for the State of California. (b) District PSD Plans. (1) The PSD rules for Sacramento... of PSD increments. (ii) Those projects which are major stationary sources or major modifications... 83-01, 5/6/83. (2) The PSD rules for North Coast Unified Air Quality Management District are approved...

  4. 40 CFR 52.270 - Significant deterioration of air quality.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... applicable State plan for the State of California. (b) District PSD Plans. (1) The PSD rules for Sacramento... of PSD increments. (ii) Those projects which are major stationary sources or major modifications... 83-01, 5/6/83. (2) The PSD rules for North Coast Unified Air Quality Management District are approved...

  5. QCD Sum Rules and Models for Generalized Parton Distributions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anatoly Radyushkin

    2004-10-01

    I use QCD sum rule ideas to construct models for generalized parton distributions. To this end, the perturbative parts of QCD sum rules for the pion and nucleon electromagnetic form factors are interpreted in terms of GPDs and two models are discussed. One of them takes the double Borel transform at adjusted value of the Borel parameter as a model for nonforward parton densities, and another is based on the local duality relation. Possible ways of improving these Ansaetze are briefly discussed.

  6. Dipole polarizability, sum rules, mean excitation energies, and long-range dispersion coefficients for buckminsterfullerene C 60

    NASA Astrophysics Data System (ADS)

    Kumar, Ashok; Thakkar, Ajit J.

    2011-11-01

    Experimental photoabsorption cross-sections combined with constraints provided by the Kuhn-Reiche-Thomas sum rule and the high-energy behavior of the dipole-oscillator-strength density are used to construct dipole oscillator strength distributions for buckminsterfullerene (C60). The distributions are used to predict dipole sum rules Sk, mean excitation energies Ik, the frequency dependent polarizability, and C6 coefficients for the long-range dipole-dipole interactions of C60 with a variety of atoms and molecules.

  7. 17 CFR 250.81 - Exempted transactions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... orders of the Commission pertaining to the performance of services or construction or the sale of goods shall not be applicable to the sale of water, telephone service, transportation, or a similar commodity... RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction...

  8. 17 CFR 250.81 - Exempted transactions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... orders of the Commission pertaining to the performance of services or construction or the sale of goods shall not be applicable to the sale of water, telephone service, transportation, or a similar commodity... RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and Construction...

  9. Leaching behavior of coal combustion products and the environmental implication in road construction.

    DOT National Transportation Integrated Search

    2011-04-01

    Leaching of trace elements may raise environmental concerns when using coal fly ash in road construction. US EPA is in the process : of creating the first national rule on coal ash management, including beneficial use. Meanwhile, driven by the tighte...

  10. Statistically based sustainable re-design of stormwater overflow control systems in urban catchments

    NASA Astrophysics Data System (ADS)

    Ganora, Daniele; Isacco, Silvia; Claps, Pierluigi

    2017-04-01

    Control and reduction of pollution from stormwater overflow is a major concern for municipalities to manage the quality of the receiving water bodies according to the Framework Water Directive 2000/60/CE. In this regard, assessment studies of the potential pollution load from sewer networks recognize the need for adaptation and upgrade of existing drainage systems, which can be achieved with either traditional water works (detention tanks, increase of wastewater treatment plant capacity, etc.) or even Nature-based solutions (constructed wetlands, restored floodplains, etc.) sometimes used in combination. Nature-based solutions are recently receiving consistent attentions as they are able to enhance urban and degraded environments being, in the same time, more resilient and adaptable to climatic and anthropic changes than most traditional engineering works. On the other hand, restoration of the urban environment using natural absorbing surfaces requires diffuse interventions, high costs and a considerable amount of time. In this work we investigate how simple, economically-sustainable and quick solutions to the problem at hand can be addressed by changes in the management rules when pumping stations play a role in sewer systems. In particular, we provide a statistically-based framework to be used in the calibration of the management rules, facing improved quality of overflows from sewer systems. Typical pumping rules favor a massive delivery of stormwater volumes to the wastewater treatment plans, requiring large storage tanks in the sewer network, heavy pumping power and reducing the efficiency of the treatment plant due to pollutant dilution. In this study we show that it is possible to optimize the pumping rule in order to reduce pumped volumes to the plant (thus saving energy), while simultaneously keeping high pollutant concentration. On the other hand, larger low-concentration overflow volumes are released outside the sewer network with respect to the standard pumping rules. Such released volumes could be efficiently processed by nature-based solutions, like for instance constructed wetlands, to reduce the final pollutant impact on the environment. The proposed procedure is based on the previous knowledge of the precipitation forcing and of a quantity/quality model of the sewer network. The method provides marginal and joint probability distributions of water volumes and pollutant concentration (or mass) delivered toward the wastewater treatment plant and the Nature-based system, with the aim of supporting a more efficient design of the whole sewer system. A practical example of application is provided for illustrative purposes.

  11. 77 FR 22500 - Approval and Promulgation of State Implementation Plans; Missouri: Prevention of Significant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... NSR revisions are to the Construction Permits Required Rule and the Emissions Banking and Trading Rule... at the Air Planning and Development Branch, Air and Waste Management Division, U.S. Environmental... inspection. The Regional Office's official hours of business are Monday through Friday, 8 a.m. to 4:30 p.m...

  12. 77 FR 34897 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Permit to Construct...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-12

    ...-0394, Ms. Kathleen Cox, Associate Director, Office of Permits and Air Toxics, Mailcode 3AP10, U.S... preconstruction permitting requirements under Maryland's New Source Review (NSR) program. In the Final Rules section of this Federal Register, EPA is approving the State's SIP submittal as a direct final rule...

  13. 77 FR 28543 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Permit To Construct...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-15

    ...-0292, Ms. Kathleen Cox, Associate Director, Office of Permits and Air Toxics, Mailcode 3AP10, U.S... preconstruction permitting requirements under Maryland's New Source Review (NSR) program. In the Final Rules section of this Federal Register, EPA is approving the State's SIP submittal as a direct final rule...

  14. An Axiomatic Theory of Cognition and Writing.

    ERIC Educational Resources Information Center

    Grunig, James E.; And Others

    Noting that although a great deal of empirical research has been done to investigate the writing rules commonly taught, this paper points out that no one has yet constructed a deep theory of the relationship between cognition and writing that confirms the writing rules and explains how they work. The paper then uses theories and research in the…

  15. Teaching with Procedural Variation: A Chinese Way of Promoting Deep Understanding of Mathematics

    ERIC Educational Resources Information Center

    Lai, Mun Yee; Murray, Sara

    2012-01-01

    In mathematics education, there has been tension between deep learning and repetitive learning. Western educators often emphasize the need for students to construct a conceptual understanding of mathematical symbols and rules before they practise the rules (Li, 2006). On the other hand, Chinese learners tend to be oriented towards rote learning…

  16. 40 CFR 60.1570 - What is the “model rule” in this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission Guidelines and Compliance Times for Small Municipal Waste Combustion Units Constructed on or Before August 30, 1999 Use of Model Rule § 60.1570 What is the “model rule” in this subpart? (a) The model rule is the portion of the...

  17. Sulfur Dioxide (SO2) Emissions From Onshore Natural Gas Processing for Which Construction, Reconstruction, or Modification Commenced After January 20, 1984, and on or Before August 23, 2011: New Source Performance Standards (NSPS)

    EPA Pesticide Factsheets

    Learn more about the NSPS regulation for SO2 emissions from onshore natural gas processing by reading the rule history, rule summary, federal register notices and the code of federal regulations subpart

  18. An Intelligent Decision Support System for Workforce Forecast

    DTIC Science & Technology

    2011-01-01

    ARIMA ) model to forecast the demand for construction skills in Hong Kong. This model was based...Decision Trees ARIMA Rule Based Forecasting Segmentation Forecasting Regression Analysis Simulation Modeling Input-Output Models LP and NLP Markovian...data • When results are needed as a set of easily interpretable rules 4.1.4 ARIMA Auto-regressive, integrated, moving-average ( ARIMA ) models

  19. 12 CFR 133.11 - Other definitions and rules of construction used in this part.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... used in this part. 133.11 Section 133.11 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY DISCLOSURE AND REPORTING OF CRA-RELATED AGREEMENTS § 133.11 Other definitions and rules... whether an agreement is a covered agreement under § 133.2, an affiliate includes any company that would be...

  20. Studying the Effects of Nuclear Weapons Using a Slide-Rule Computer

    ERIC Educational Resources Information Center

    Shastri, Ananda

    2007-01-01

    This paper describes the construction of a slide-rule computer that allows one to quickly determine magnitudes of several effects that result from the detonation of a nuclear device. Suggestions for exercises are also included that allow high school and college-level physics students to explore scenarios involving these effects. It is hoped that…

  1. 75 FR 10438 - Effluent Limitations Guidelines and Standards for the Construction and Development Point Source...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    ... CONTACT: Mr. Jesse W. Pritts at 202-566-1038 ( [email protected] ). SUPPLEMENTARY INFORMATION... Executive Order 13084. 63 FR 27655 (May 10, 1998). This rule will not have substantial direct effects on the.... 64 FR 43255 (August 10, 1999). This rule also is not subject to Executive Order 13045, 62 FR 19885...

  2. 40 CFR 60.2570 - What are the principal components of the model rule?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false What are the principal components of... Construction On or Before November 30, 1999 Use of Model Rule § 60.2570 What are the principal components of... (k) of this section. (a) Increments of progress toward compliance. (b) Waste management plan. (c...

  3. Location Prediction Based on Transition Probability Matrices Constructing from Sequential Rules for Spatial-Temporal K-Anonymity Dataset

    PubMed Central

    Liu, Zhao; Zhu, Yunhong; Wu, Chenxue

    2016-01-01

    Spatial-temporal k-anonymity has become a mainstream approach among techniques for protection of users’ privacy in location-based services (LBS) applications, and has been applied to several variants such as LBS snapshot queries and continuous queries. Analyzing large-scale spatial-temporal anonymity sets may benefit several LBS applications. In this paper, we propose two location prediction methods based on transition probability matrices constructing from sequential rules for spatial-temporal k-anonymity dataset. First, we define single-step sequential rules mined from sequential spatial-temporal k-anonymity datasets generated from continuous LBS queries for multiple users. We then construct transition probability matrices from mined single-step sequential rules, and normalize the transition probabilities in the transition matrices. Next, we regard a mobility model for an LBS requester as a stationary stochastic process and compute the n-step transition probability matrices by raising the normalized transition probability matrices to the power n. Furthermore, we propose two location prediction methods: rough prediction and accurate prediction. The former achieves the probabilities of arriving at target locations along simple paths those include only current locations, target locations and transition steps. By iteratively combining the probabilities for simple paths with n steps and the probabilities for detailed paths with n-1 steps, the latter method calculates transition probabilities for detailed paths with n steps from current locations to target locations. Finally, we conduct extensive experiments, and correctness and flexibility of our proposed algorithm have been verified. PMID:27508502

  4. 18 CFR 2.13 - Design and construction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Design and construction. 2.13 Section 2.13 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

  5. 18 CFR 2.13 - Design and construction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Design and construction. 2.13 Section 2.13 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

  6. 18 CFR 2.13 - Design and construction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Design and construction. 2.13 Section 2.13 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

  7. 18 CFR 2.13 - Design and construction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Design and construction. 2.13 Section 2.13 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of General Policy and...

  8. A case study : Michigan Intelligent Transportation System Center : use of a design/build/warranty contract

    DOT National Transportation Integrated Search

    2000-03-01

    Many ITS projects are stand-alone in nature, and do not have to be procured under rules for construction. The installation of field devices and communications infrastructure often meets the definition of construction. However, if a project involves t...

  9. New Source Review (NSR) Air Permitting and Energy Efficiency for Industrial Projects, IECA Manufacturers for Energy Efficiency Coalition Meeting (Presentation) – April 18, 2012

    EPA Pesticide Factsheets

    This presentation provides information about major new source review (NSR), including recent improvement changes and court rulings, flexible air permits rule, significant deterioration rules, and energy efficiency considerations.

  10. Language Symmetry: A Force behind Persuasion

    ERIC Educational Resources Information Center

    Yeager, Joseph; Sommer, Linda

    2012-01-01

    Language operates according to rules. Rules mean prediction. The application of these language rules to persuasive campaigns through linguistic technology can result in major gains in advertising, political and marketing outcomes. For qualitative researchers in communications, marketing and messaging, one area of persuasive language technology can…

  11. Modeling for (physical) biologists: an introduction to the rule-based approach

    PubMed Central

    Chylek, Lily A; Harris, Leonard A; Faeder, James R; Hlavacek, William S

    2015-01-01

    Models that capture the chemical kinetics of cellular regulatory networks can be specified in terms of rules for biomolecular interactions. A rule defines a generalized reaction, meaning a reaction that permits multiple reactants, each capable of participating in a characteristic transformation and each possessing certain, specified properties, which may be local, such as the state of a particular site or domain of a protein. In other words, a rule defines a transformation and the properties that reactants must possess to participate in the transformation. A rule also provides a rate law. A rule-based approach to modeling enables consideration of mechanistic details at the level of functional sites of biomolecules and provides a facile and visual means for constructing computational models, which can be analyzed to study how system-level behaviors emerge from component interactions. PMID:26178138

  12. 77 FR 59581 - Personal Identity Verification, Release and Handling of Restricted Information, Protection of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... of a major NASA FAR Supplement (NFS) rewrite, any changes from the withdrawn rules that continue to... (NFS). Public comments were received on all three rules. However, circumstances at the time prevented... cancelled without further action. At this time, NASA is in process of a major NFS rewrite, and any changes...

  13. 75 FR 43892 - Approval and Promulgation of Implementation Plans; New York Prevention of Significant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... proposal related to the Tailoring Rule thresholds. III. What is EPA's analysis of New York's NSR rule...) Program. New York's amendments to Part 201 revise the definition for ``major stationary source or major... Parts 200 and 201, including the new or revised definitions are consistent with Federal guidance, EPA is...

  14. 78 FR 7137 - National Emission Standards for Hazardous Air Pollutants for Major Sources: Industrial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... 2011 final rule was, therefore, in effect until publication of this action. Summary of Major... economy this final rule effects, the EPA is revising certain subcategories for boilers and process heaters...,000 to $59,000. Non-monetized Benefits Health effects from exposure to HAP (39,000 tons of HCl, 500...

  15. Quantum Tic-Tac-Toe as Metaphor for Quantum Physics

    NASA Astrophysics Data System (ADS)

    Goff, Allan; Lehmann, Dale; Siegel, Joel

    2004-02-01

    Quantum Tic-Tac-Toe is presented as an abstract quantum system derived from the rules of Classical Tic-Tac-Toe. Abstract quantum systems can be constructed from classical systems by the addition of three types of rules; rules of Superposition, rules of Entanglement, and rules of Collapse. This is formally done for Quantum Tic-Tac-Toe. As a part of this construction it is shown that abstract quantum systems can be viewed as an ensemble of classical systems. That is, the state of a quantum game implies a set of simultaneous classical games. The number and evolution of the ensemble of classical games is driven by the superposition, entanglement, and collapse rules. Various aspects and play situations provide excellent metaphors for standard features of quantum mechanics. Several of the more significant metaphors are discussed, including a measurement mechanism, the correspondence principle, Everett's Many Worlds Hypothesis, an ascertainity principle, and spooky action at a distance. Abstract quantum systems also show the consistency of backwards-in-time causality, and the influence on the present of both pasts and futures that never happened. The strongest logical argument against faster-than-light (FTL) phenomena is that since FTL implies backwards-in-time causality, temporal paradox is an unavoidable consequence of FTL; hence FTL is impossible. Since abstract quantum systems support backwards-in-time causality but avoid temporal paradox through pruning of the classical ensemble, it may be that quantum based FTL schemes are possible allowing backwards-in-time causality, but prohibiting temporal paradox.

  16. Music models aberrant rule decoding and reward valuation in dementia

    PubMed Central

    Clark, Camilla N; Golden, Hannah L; McCallion, Oliver; Nicholas, Jennifer M; Cohen, Miriam H; Slattery, Catherine F; Paterson, Ross W; Fletcher, Phillip D; Mummery, Catherine J; Rohrer, Jonathan D; Crutch, Sebastian J; Warren, Jason D

    2018-01-01

    Abstract Aberrant rule- and reward-based processes underpin abnormalities of socio-emotional behaviour in major dementias. However, these processes remain poorly characterized. Here we used music to probe rule decoding and reward valuation in patients with frontotemporal dementia (FTD) syndromes and Alzheimer’s disease (AD) relative to healthy age-matched individuals. We created short melodies that were either harmonically resolved (‘finished’) or unresolved (‘unfinished’); the task was to classify each melody as finished or unfinished (rule processing) and rate its subjective pleasantness (reward valuation). Results were adjusted for elementary pitch and executive processing; neuroanatomical correlates were assessed using voxel-based morphometry. Relative to healthy older controls, patients with behavioural variant FTD showed impairments of both musical rule decoding and reward valuation, while patients with semantic dementia showed impaired reward valuation but intact rule decoding, patients with AD showed impaired rule decoding but intact reward valuation and patients with progressive non-fluent aphasia performed comparably to healthy controls. Grey matter associations with task performance were identified in anterior temporal, medial and lateral orbitofrontal cortices, previously implicated in computing diverse biological and non-biological rules and rewards. The processing of musical rules and reward distils cognitive and neuroanatomical mechanisms relevant to complex socio-emotional dysfunction in major dementias. PMID:29186630

  17. Regulatory Developments in Cable Television.

    ERIC Educational Resources Information Center

    Federal Communications Commission, Washington, DC.

    This report summarizes major rule making actions since 1972, current rules and regulations, and guidelines for citizen participation in FCC (Federal Communications Commission) processes related to cable television regulation. A large portion of the report pertains to current rules and regulations in the areas of certificate of compliance,…

  18. 17 CFR 250.82 - Temporary exemption from section 13.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (CONTINUED) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Service, Sales and... principally engaged in performing services or construction for, or making sales to, associates of such... performance of services or construction for associate companies on the basis of cost and with the provisions...

  19. 19 CFR 201.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Program accessibility: New construction and alterations. 201.151 Section 201.151 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES... Activities Conducted by the U.S. International Trade Commission § 201.151 Program accessibility: New...

  20. 19 CFR 201.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Program accessibility: New construction and alterations. 201.151 Section 201.151 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES... Activities Conducted by the U.S. International Trade Commission § 201.151 Program accessibility: New...

  1. 19 CFR 201.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 3 2014-04-01 2014-04-01 false Program accessibility: New construction and alterations. 201.151 Section 201.151 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES... Activities Conducted by the U.S. International Trade Commission § 201.151 Program accessibility: New...

  2. 19 CFR 201.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 3 2012-04-01 2012-04-01 false Program accessibility: New construction and alterations. 201.151 Section 201.151 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES... Activities Conducted by the U.S. International Trade Commission § 201.151 Program accessibility: New...

  3. 19 CFR 201.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 3 2013-04-01 2013-04-01 false Program accessibility: New construction and alterations. 201.151 Section 201.151 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES... Activities Conducted by the U.S. International Trade Commission § 201.151 Program accessibility: New...

  4. 22 CFR 228.35 - Construction services from foreign-owned local firms.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Construction services from foreign-owned local firms. 228.35 Section 228.35 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE, ORIGIN AND NATIONALITY FOR COMMODITIES AND SERVICES FINANCED BY USAID Conditions Governing the...

  5. 12 CFR 533.11 - Other definitions and rules of construction used in this part.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., association, trust, joint venture, joint stock company, corporation, limited liability corporation, company... of construction used in this part. (a) Affiliate. Affiliate means— (1) Any company that controls, is controlled by, or is under common control with another company; and (2) For the purpose of determining...

  6. La Gramatica Ingles: Libro de Trabajo (English Grammar: Workbook).

    ERIC Educational Resources Information Center

    Rogers, Paul

    This student workbook is designed for native Spanish-speaking learners of English as a second language, and presents instruction in basic English grammatical constructions and usage, as well as some vocabulary development. Lessons include basic descriptions of the constructions and rules in applying them, and a brief exercise reinforcing the…

  7. 77 FR 1407 - Regulated Navigation Area; Memorial Bridge Construction, Piscataqua River, Portsmouth, NH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ...-AA11 Regulated Navigation Area; Memorial Bridge Construction, Piscataqua River, Portsmouth, NH AGENCY... River under and surrounding the Memorial Bridge between Portsmouth, NH and Kittery, ME. This temporary interim rule is necessary to provide for the safety of life on the navigable waters during bridge...

  8. Developing a semantic web model for medical differential diagnosis recommendation.

    PubMed

    Mohammed, Osama; Benlamri, Rachid

    2014-10-01

    In this paper we describe a novel model for differential diagnosis designed to make recommendations by utilizing semantic web technologies. The model is a response to a number of requirements, ranging from incorporating essential clinical diagnostic semantics to the integration of data mining for the process of identifying candidate diseases that best explain a set of clinical features. We introduce two major components, which we find essential to the construction of an integral differential diagnosis recommendation model: the evidence-based recommender component and the proximity-based recommender component. Both approaches are driven by disease diagnosis ontologies designed specifically to enable the process of generating diagnostic recommendations. These ontologies are the disease symptom ontology and the patient ontology. The evidence-based diagnosis process develops dynamic rules based on standardized clinical pathways. The proximity-based component employs data mining to provide clinicians with diagnosis predictions, as well as generates new diagnosis rules from provided training datasets. This article describes the integration between these two components along with the developed diagnosis ontologies to form a novel medical differential diagnosis recommendation model. This article also provides test cases from the implementation of the overall model, which shows quite promising diagnostic recommendation results.

  9. Occupational Consciousness.

    PubMed

    Ramugondo, Elelwani L

    2015-10-02

    Occupational consciousness refers to ongoing awareness of the dynamics of hegemony and recognition that dominant practices are sustained through what people do every day, with implications for personal and collective health. The emergence of the construct in post-apartheid South Africa signifies the country's ongoing struggle with negotiating long-standing dynamics of power that were laid down during colonialism, and maintained under black majority rule. Consciousness, a key component of the new terminology, is framed from post-colonial perspectives - notably work by Biko and Fanon - and grounded in the philosophy of liberation, in order to draw attention to continuing unequal intersubjective relations that play out through human occupation. The paper also draws important links between occupational consciousness and other related constructs, namely occupational possibilities, occupational choice, occupational apartheid, and collective occupation. The use of the term 'consciousness' in sociology, with related or different meanings, is also explored. Occupational consciousness is then advanced as a critical notion that frames everyday doing as a potentially liberating response to oppressive social structures. This paper advances theorizing as a scholarly practice in occupational science, and could potentially expand inter or transdisciplinary work for critical conceptualizations of human occupation.

  10. Equipment Leaks of Volatile Organic Compounds From Onshore Natural Gas Processing Plants for Which Construction, Reconstruction, or Modification Commenced After January 20, 1984, and on or Before August 23, 2011: New Source Performance Standards (NSPS)

    EPA Pesticide Factsheets

    Learn about the NSPS regulation for equipment leaks of Volatile Organic Compounds (VOC) from onshore natural gas processing plants by reading the rule summary, rule history, federal register citations, and the code of federal regulations

  11. Power and Gender in Ancient Egypt: The Case of Hatshepsut

    ERIC Educational Resources Information Center

    Hilliard, Kristina; Wurtzel, Kate

    2009-01-01

    Hatshepsut (1479-1458 B.C.E) ruled New Kingdom Egypt for roughly 20 years as one of the few female pharaohs in the history of ancient Egypt. Her rule began when her husband died and her stepson was too young to be pharaoh. To legitimize her role as pharaoh, Hatshepsut began a significant building campaign by constructing numerous images, temples,…

  12. An Algebraic Approach to the Study and Optimization of the Set of Rules of a Conditional Rewrite System

    NASA Astrophysics Data System (ADS)

    Makhortov, S. D.

    2018-03-01

    An algebraic system containing the semantics of a set of rules of the conditional equational theory (or the conditional term rewriting system) is introduced. The following basic questions are considered for the given model: existence of logical closure, structure of logical closure, possibility of equivalent transformations, and construction of logical reduction. The obtained results can be applied to the analysis and automatic optimization of the corresponding set of rules. The basis for the given research is the theory of lattices and binary relations.

  13. 75 FR 22548 - Requirements for Control Technology Determinations for Major Sources in Accordance With Clean Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ..., Sections 112(g) and 112(j) AGENCY: Environmental Protection Agency (EPA). ACTION: Extension of public... case-by-case emission limits for major sources of hazardous air pollutants under section 112(j) of the..., when EPA published a proposed rule (75 FR 15655) amending the Section 112(j) rule (40 CFR part 63...

  14. Implicit Detection of Poetic Harmony by the Naïve Brain.

    PubMed

    Vaughan-Evans, Awel; Trefor, Robat; Jones, Llion; Lynch, Peredur; Jones, Manon W; Thierry, Guillaume

    2016-01-01

    The power of poetry is universally acknowledged, but it is debatable whether its appreciation is reserved for experts. Here, we show that readers with no particular knowledge of a traditional form of Welsh poetry unconsciously distinguish phrases conforming to its complex poetic construction rules from those that violate them. We studied the brain response of native speakers of Welsh as they read meaningful sentences ending in a word that either complied with strict poetic construction rules, violated rules of consonantal repetition, violated stress pattern, or violated both these constraints. Upon reading the last word of each sentence, participants indicated sentence acceptability. As expected, our inexperienced participants did not explicitly distinguish between sentences that conformed to the poetic rules from those that violated them. However, in the case of orthodox sentences, the critical word elicited a distinctive brain response characteristic of target detection -the P3b- as compared to the other conditions, showing that speakers of Welsh with no expertise of this particular form of poetry implicitly detect poetic harmony. These results show for the first time that before we even consider literal meaning, the musical properties of poetry speak to the human mind in ways that escape consciousness.

  15. Implicit Detection of Poetic Harmony by the Naïve Brain

    PubMed Central

    Vaughan-Evans, Awel; Trefor, Robat; Jones, Llion; Lynch, Peredur; Jones, Manon W.; Thierry, Guillaume

    2016-01-01

    The power of poetry is universally acknowledged, but it is debatable whether its appreciation is reserved for experts. Here, we show that readers with no particular knowledge of a traditional form of Welsh poetry unconsciously distinguish phrases conforming to its complex poetic construction rules from those that violate them. We studied the brain response of native speakers of Welsh as they read meaningful sentences ending in a word that either complied with strict poetic construction rules, violated rules of consonantal repetition, violated stress pattern, or violated both these constraints. Upon reading the last word of each sentence, participants indicated sentence acceptability. As expected, our inexperienced participants did not explicitly distinguish between sentences that conformed to the poetic rules from those that violated them. However, in the case of orthodox sentences, the critical word elicited a distinctive brain response characteristic of target detection –the P3b– as compared to the other conditions, showing that speakers of Welsh with no expertise of this particular form of poetry implicitly detect poetic harmony. These results show for the first time that before we even consider literal meaning, the musical properties of poetry speak to the human mind in ways that escape consciousness. PMID:27933025

  16. Analysis on composition rules of Chinese patent drugs treating pain-related diseases based on data mining method.

    PubMed

    Tang, Shi-Huan; Shen, Dan; Yang, Hong-Jun

    2017-08-24

    To analyze the composition rules of oral prescriptions in the treatment of headache, stomachache and dysmenorrhea recorded in National Standard for Chinese Patent Drugs (NSCPD) enacted by Ministry of Public Health of China and then make comparison between them to better understand pain treatment in different regions of human body. Constructed NSCPD database had been constructed in 2014. Prescriptions treating the three pain-related diseases were searched and screened from the database. Then data mining method such as association rules analysis and complex system entropy method integrated in the data mining software Traditional Chinese Medicine Inheritance Support System (TCMISS) were applied to process the data. Top 25 drugs with high frequency in the treatment of each disease were selected, and 51, 33 and 22 core combinations treating headache, stomachache and dysmenorrhea respectively were mined out as well. The composition rules of the oral prescriptions for treating headache, stomachache and dysmenorrhea recorded in NSCPD has been summarized. Although there were similarities between them, formula varied according to different locations of pain. It can serve as an evidence and reference for clinical treatment and new drug development.

  17. Construction of a Clinical Decision Support System for Undergoing Surgery Based on Domain Ontology and Rules Reasoning

    PubMed Central

    Bau, Cho-Tsan; Huang, Chung-Yi

    2014-01-01

    Abstract Objective: To construct a clinical decision support system (CDSS) for undergoing surgery based on domain ontology and rules reasoning in the setting of hospitalized diabetic patients. Materials and Methods: The ontology was created with a modified ontology development method, including specification and conceptualization, formalization, implementation, and evaluation and maintenance. The Protégé–Web Ontology Language editor was used to implement the ontology. Embedded clinical knowledge was elicited to complement the domain ontology with formal concept analysis. The decision rules were translated into JENA format, which JENA can use to infer recommendations based on patient clinical situations. Results: The ontology includes 31 classes and 13 properties, plus 38 JENA rules that were built to generate recommendations. The evaluation studies confirmed the correctness of the ontology, acceptance of recommendations, satisfaction with the system, and usefulness of the ontology for glycemic management of diabetic patients undergoing surgery, especially for domain experts. Conclusions: The contribution of this research is to set up an evidence-based hybrid ontology and an evaluation method for CDSS. The system can help clinicians to achieve inpatient glycemic control in diabetic patients undergoing surgery while avoiding hypoglycemia. PMID:24730353

  18. Construction of a clinical decision support system for undergoing surgery based on domain ontology and rules reasoning.

    PubMed

    Bau, Cho-Tsan; Chen, Rung-Ching; Huang, Chung-Yi

    2014-05-01

    To construct a clinical decision support system (CDSS) for undergoing surgery based on domain ontology and rules reasoning in the setting of hospitalized diabetic patients. The ontology was created with a modified ontology development method, including specification and conceptualization, formalization, implementation, and evaluation and maintenance. The Protégé-Web Ontology Language editor was used to implement the ontology. Embedded clinical knowledge was elicited to complement the domain ontology with formal concept analysis. The decision rules were translated into JENA format, which JENA can use to infer recommendations based on patient clinical situations. The ontology includes 31 classes and 13 properties, plus 38 JENA rules that were built to generate recommendations. The evaluation studies confirmed the correctness of the ontology, acceptance of recommendations, satisfaction with the system, and usefulness of the ontology for glycemic management of diabetic patients undergoing surgery, especially for domain experts. The contribution of this research is to set up an evidence-based hybrid ontology and an evaluation method for CDSS. The system can help clinicians to achieve inpatient glycemic control in diabetic patients undergoing surgery while avoiding hypoglycemia.

  19. Majority rule has transition ratio 4 on Yule trees under a 2-state symmetric model.

    PubMed

    Mossel, Elchanan; Steel, Mike

    2014-11-07

    Inferring the ancestral state at the root of a phylogenetic tree from states observed at the leaves is a problem arising in evolutionary biology. The simplest technique - majority rule - estimates the root state by the most frequently occurring state at the leaves. Alternative methods - such as maximum parsimony - explicitly take the tree structure into account. Since either method can outperform the other on particular trees, it is useful to consider the accuracy of the methods on trees generated under some evolutionary null model, such as a Yule pure-birth model. In this short note, we answer a recently posed question concerning the performance of majority rule on Yule trees under a symmetric 2-state Markovian substitution model of character state change. We show that majority rule is accurate precisely when the ratio of the birth (speciation) rate of the Yule process to the substitution rate exceeds the value 4. By contrast, maximum parsimony has been shown to be accurate only when this ratio is at least 6. Our proof relies on a second moment calculation, coupling, and a novel application of a reflection principle. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Planning and scheduling the Hubble Space Telescope: Practical application of advanced techniques

    NASA Technical Reports Server (NTRS)

    Miller, Glenn E.

    1994-01-01

    NASA's Hubble Space Telescope (HST) is a major astronomical facility that was launched in April, 1990. In late 1993, the first of several planned servicing missions refurbished the telescope, including corrections for a manufacturing flaw in the primary mirror. Orbiting above the distorting effects of the Earth's atmosphere, the HST provides an unrivaled combination of sensitivity, spectral coverage and angular resolution. The HST is arguably the most complex scientific observatory ever constructed and effective use of this valuable resource required novel approaches to astronomical observation and the development of advanced software systems including techniques to represent scheduling preferences and constraints, a constraint satisfaction problem (CSP) based scheduler and a rule based planning system. This paper presents a discussion of these systems and the lessons learned from operational experience.

  1. Triggers for Autism: Genetic and Environmental Factors

    PubMed Central

    Matsuzaki, Hideo; Iwata, Keiko; Manabe, Takayuki; Mori, Norio

    2012-01-01

    This report reviews the research on the factors that cause autism. In several studies, these factors have been verified by reproducing them in autistic animal models. Clinical research has demonstrated that genetic and environmental factors play a major role in the development of autism. However, most cases are idiopathic, and no single factor can explain the trends in the pathology and prevalence of autism. At the time of this writing, autism is viewed more as a multi-factorial disorder. However, the existence of an unknown factor that may be common in all autistic cases cannot be ruled out. It is hoped that future biological studies of autism will help construct a new theory that can interpret the pathology of autism in a coherent manner. To achieve this, large-scale epidemiological research is essential. PMID:23650465

  2. JPRS Report, Soviet Union, Foreign Military Review, No. 5, May 1988

    DTIC Science & Technology

    1988-10-31

    nology, Carnegie-Mellon University, and Stanford Uni- versity taking the lead. New constructive ideas were advanced in this period for simulating human...for representing stereotyped situations), products (logical constructions according to rules such as "if..., then..."), semantic networks (formal...battle). A prototype of the expert system, OB.l KB (Order of Battlefield [sic] Variant No. 1 Knowledge Base), was constructed as a result of

  3. Measuring the construct of executive control in schizophrenia: defining and validating translational animal paradigms for discovery research.

    PubMed

    Gilmour, Gary; Arguello, Alexander; Bari, Andrea; Brown, Verity J; Carter, Cameron; Floresco, Stan B; Jentsch, David J; Tait, David S; Young, Jared W; Robbins, Trevor W

    2013-11-01

    Executive control is an aspect of cognitive function known to be impaired in schizophrenia. Previous meetings of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) group have more precisely defined executive control in terms of two constructs: "rule generation and selection", and "dynamic adjustments of control". Next, human cognitive tasks that may effectively measure performance with regard to these constructs were identified to be developed into practical and reliable measures for use in treatment development. The aim of this round of CNTRICS meetings was to define animal paradigms that have sufficient promise to warrant further investigation for their utility in measuring these constructs. Accordingly, "reversal learning" and the "attentional set-shifting task" were nominated to assess the construct of rule generation and selection, and the "stop signal task" for the construct of dynamic adjustments of control. These tasks are described in more detail here, with a particular focus on their utility for drug discovery efforts. Presently, each assay has strengths and weaknesses with regard to this point and increased emphasis on improving practical aspects of testing, understanding predictive validity, and defining biomarkers of performance represent important objectives in attaining confidence in translational validity here. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

  4. Engineering monitoring expert system's developer

    NASA Technical Reports Server (NTRS)

    Lo, Ching F.

    1991-01-01

    This research project is designed to apply artificial intelligence technology including expert systems, dynamic interface of neural networks, and hypertext to construct an expert system developer. The developer environment is specifically suited to building expert systems which monitor the performance of ground support equipment for propulsion systems and testing facilities. The expert system developer, through the use of a graphics interface and a rule network, will be transparent to the user during rule constructing and data scanning of the knowledge base. The project will result in a software system that allows its user to build specific monitoring type expert systems which monitor various equipments used for propulsion systems or ground testing facilities and accrues system performance information in a dynamic knowledge base.

  5. A neural network architecture for implementation of expert systems for real time monitoring

    NASA Technical Reports Server (NTRS)

    Ramamoorthy, P. A.

    1991-01-01

    Since neural networks have the advantages of massive parallelism and simple architecture, they are good tools for implementing real time expert systems. In a rule based expert system, the antecedents of rules are in the conjunctive or disjunctive form. We constructed a multilayer feedforward type network in which neurons represent AND or OR operations of rules. Further, we developed a translator which can automatically map a given rule base into the network. Also, we proposed a new and powerful yet flexible architecture that combines the advantages of both fuzzy expert systems and neural networks. This architecture uses the fuzzy logic concepts to separate input data domains into several smaller and overlapped regions. Rule-based expert systems for time critical applications using neural networks, the automated implementation of rule-based expert systems with neural nets, and fuzzy expert systems vs. neural nets are covered.

  6. Optical Thomas-Reiche-Kuhn sum rules.

    PubMed

    Barnett, Stephen M; Loudon, Rodney

    2012-01-06

    The Thomas-Reiche-Kuhn sum rule is a fundamental consequence of the position-momentum commutation relation for an atomic electron and it provides an important constraint on the transition matrix elements for an atom. Analogously, the commutation relations for the electromagnetic field operators in a magnetodielectric medium constrain the properties of the dispersion relations for the medium through four sum rules for the allowed phase and group velocities for polaritons propagating through the medium. These rules apply to all bulk media including the metamaterials designed to provide negative refractive indices. An immediate consequence of this is that it is not possible to construct a medium in which all the polariton modes for a given wavelength lie in the negative-index region.

  7. Optical Thomas-Reiche-Kuhn Sum Rules

    NASA Astrophysics Data System (ADS)

    Barnett, Stephen M.; Loudon, Rodney

    2012-01-01

    The Thomas-Reiche-Kuhn sum rule is a fundamental consequence of the position-momentum commutation relation for an atomic electron and it provides an important constraint on the transition matrix elements for an atom. Analogously, the commutation relations for the electromagnetic field operators in a magnetodielectric medium constrain the properties of the dispersion relations for the medium through four sum rules for the allowed phase and group velocities for polaritons propagating through the medium. These rules apply to all bulk media including the metamaterials designed to provide negative refractive indices. An immediate consequence of this is that it is not possible to construct a medium in which all the polariton modes for a given wavelength lie in the negative-index region.

  8. Modeling the prediction of business intelligence system effectiveness.

    PubMed

    Weng, Sung-Shun; Yang, Ming-Hsien; Koo, Tian-Lih; Hsiao, Pei-I

    2016-01-01

    Although business intelligence (BI) technologies are continually evolving, the capability to apply BI technologies has become an indispensable resource for enterprises running in today's complex, uncertain and dynamic business environment. This study performed pioneering work by constructing models and rules for the prediction of business intelligence system effectiveness (BISE) in relation to the implementation of BI solutions. For enterprises, effectively managing critical attributes that determine BISE to develop prediction models with a set of rules for self-evaluation of the effectiveness of BI solutions is necessary to improve BI implementation and ensure its success. The main study findings identified the critical prediction indicators of BISE that are important to forecasting BI performance and highlighted five classification and prediction rules of BISE derived from decision tree structures, as well as a refined regression prediction model with four critical prediction indicators constructed by logistic regression analysis that can enable enterprises to improve BISE while effectively managing BI solution implementation and catering to academics to whom theory is important.

  9. On the Universality and Non-Universality of Spiking Neural P Systems With Rules on Synapses.

    PubMed

    Song, Tao; Xu, Jinbang; Pan, Linqiang

    2015-12-01

    Spiking neural P systems with rules on synapses are a new variant of spiking neural P systems. In the systems, the neuron contains only spikes, while the spiking/forgetting rules are moved on the synapses. It was obtained that such system with 30 neurons (using extended spiking rules) or with 39 neurons (using standard spiking rules) is Turing universal. In this work, this number is improved to 6. Specifically, we construct a Turing universal spiking neural P system with rules on synapses having 6 neurons, which can generate any set of Turing computable natural numbers. As well, it is obtained that spiking neural P system with rules on synapses having less than two neurons are not Turing universal: i) such systems having one neuron can characterize the family of finite sets of natural numbers; ii) the family of sets of numbers generated by the systems having two neurons is included in the family of semi-linear sets of natural numbers.

  10. 26 CFR 1.148-9 - Arbitrage rules for refunding issues.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., representative portions of the portfolio of nonpurpose investments and the portfolio of purpose investments of... a reserve fund or a construction fund for a prior issue. (B) Mark-to-market safe harbor for... carry out the governmental purpose of the prior issue (e.g., a construction fund), those amounts must be...

  11. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  12. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  13. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  14. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  15. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  16. Social Construction of Computer Experience in a First-Grade Classroom: Social Processes and Mediating Artifacts.

    ERIC Educational Resources Information Center

    Wang, X. Christine; Ching, Cynthia Carter

    2003-01-01

    This ethnographic study investigated first-graders' social construction of their classroom computer experience. Findings showed that children constantly negotiate between their own individual and collective goals in the classroom as they create their own definition of computer use while conforming to the teacher's rules. Considers the usefulness…

  17. 12 CFR 35.11 - Other definitions and rules of construction used in this part.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...” is any partnership, association, trust, joint venture, joint stock company, corporation, limited... construction used in this part. (a) Affiliate. “Affiliate” means— (1) Any company that controls, is controlled by, or is under common control with another company; and (2) For the purpose of determining whether...

  18. 77 FR 42988 - Updating OSHA Construction Standards Based on National Consensus Standards; Head Protection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    .... OSHA-2011-0184] RIN 1218-AC65 Updating OSHA Construction Standards Based on National Consensus... Administration (OSHA), Department of Labor. ACTION: Direct final rule; correction. SUMMARY: OSHA is correcting a... confusion resulting from a drafting error. OSHA published the DFR on June 22, 2012 (77 FR 37587). OSHA also...

  19. 18 CFR Appendix A to Part 2 - Guidance for Determining the Acceptable Construction Area for Replacements

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Guidance for Determining the Acceptable Construction Area for Replacements A Appendix A to Part 2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

  20. 18 CFR Appendix A to Part 2 - Guidance for Determining the Acceptable Construction Area for Replacements

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Guidance for Determining the Acceptable Construction Area for Replacements A Appendix A to Part 2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

  1. 18 CFR Appendix A to Part 2 - Guidance for Determining the Acceptable Construction Area for Replacements

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Guidance for Determining the Acceptable Construction Area for Replacements A Appendix A to Part 2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY...

  2. 78 FR 59231 - Regulated Navigation Area-Tappan Zee Bridge Construction Project, Hudson River; South Nyack and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ... 1625-AA11 Regulated Navigation Area--Tappan Zee Bridge Construction Project, Hudson River; South Nyack... Hudson River surrounding the Tappan Zee Bridge. This temporary interim rule allows the Coast Guard to enforce speed and wake restrictions and prohibit all vessel traffic through the RNA during bridge...

  3. 78 FR 71546 - Safety Zone; Belt Parkway Bridge Construction, Gerritsen Inlet, Brooklyn, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... 1625-AA00 Safety Zone; Belt Parkway Bridge Construction, Gerritsen Inlet, Brooklyn, NY AGENCY: Coast... safety zone on the navigable waters of Gerritsen Inlet surrounding the Belt Parkway Bridge. This proposed rule would allow the Coast Guard to prohibit all vessel traffic through the safety zone during bridge...

  4. Problem Solving in a Middle School Robotics Design Classroom

    NASA Astrophysics Data System (ADS)

    Norton, Stephen J.; McRobbie, Campbell J.; Ginns, Ian S.

    2007-07-01

    Little research has been conducted on how students work when they are required to plan, build and evaluate artefacts in technology rich learning environments such as those supported by tools including flow charts, Labview programming and Lego construction. In this study, activity theory was used as an analytic tool to examine the social construction of meaning. There was a focus on the effect of teachers’ goals and the rules they enacted upon student use of the flow chart planning tool, and the tools of the programming language Labview and Lego construction. It was found that the articulation of a teacher’s goals via rules and divisions of labour helped to form distinct communities of learning and influenced the development of different problem solving strategies. The use of the planning tool flow charting was associated with continuity of approach, integration of problem solutions including appreciation of the nexus between construction and programming, and greater educational transformation. Students who flow charted defined problems in a more holistic way and demonstrated more methodical, insightful and integrated approaches to their use of tools. The findings have implications for teaching in design dominated learning environments.

  5. Reinforcement Learning Trees

    PubMed Central

    Zhu, Ruoqing; Zeng, Donglin; Kosorok, Michael R.

    2015-01-01

    In this paper, we introduce a new type of tree-based method, reinforcement learning trees (RLT), which exhibits significantly improved performance over traditional methods such as random forests (Breiman, 2001) under high-dimensional settings. The innovations are three-fold. First, the new method implements reinforcement learning at each selection of a splitting variable during the tree construction processes. By splitting on the variable that brings the greatest future improvement in later splits, rather than choosing the one with largest marginal effect from the immediate split, the constructed tree utilizes the available samples in a more efficient way. Moreover, such an approach enables linear combination cuts at little extra computational cost. Second, we propose a variable muting procedure that progressively eliminates noise variables during the construction of each individual tree. The muting procedure also takes advantage of reinforcement learning and prevents noise variables from being considered in the search for splitting rules, so that towards terminal nodes, where the sample size is small, the splitting rules are still constructed from only strong variables. Last, we investigate asymptotic properties of the proposed method under basic assumptions and discuss rationale in general settings. PMID:26903687

  6. A Short Note on Rules and Higher Order Rules.

    ERIC Educational Resources Information Center

    Scandura, Joseph M.

    This brief paper argues that structural analysis--an extended form of cognitive task analysis--demonstrates that both domain dependent and domain independent knowledge can be derived from specific content domains. It is noted that the major difference between the two is that lower order rules (specific knowledge) are derived directly from specific…

  7. Developmental and Individual Differences in Children's Area Judgment Rules.

    ERIC Educational Resources Information Center

    Silverman, Irwin W.; Paskewitz, Sabra Lee

    1988-01-01

    Investigated whether children in kindergarten and grades 2 and 4 applied one- or two-dimensional rules in rating areas of rectangles, triangles, and ellipses. A majority of subjects produced judgments consistent with one of the rules. The findings contradict Piaget's claim that young children are limited to one-dimensional judgments. (SKC)

  8. Rules of Thumb for Up-and-Down Economics.

    ERIC Educational Resources Information Center

    Kennedy, Peter

    1994-01-01

    Reports that economist Paul Krugman identifies three types of economic writing. Asserts that the major principles of macroeconomics can be synthesized into "Five Rules of Thumb" which can help to interpret economic news. Presents and discusses these five rules and includes a survey summary of journalists and economists on this issue.…

  9. Construction of a Phonotactic Dialect Corpus using Semiautomatic Annotation

    DTIC Science & Technology

    2007-01-01

    phonological or phonetic feature is speaker specific or commonly found in that speaker’s dialect. Historically, the sociolinguistic study of dialect...variation in speech has been limited to small-scale population studies , usually conducted through sociolinguistic interviews [1]. Dialect analysis of... study , we created a superset of rules 943 derived from phenomena described in the sociolinguistic literature [8][9][10][11]. Rule Example ROI [r]->0

  10. "You Need to Own Cats to Be a Part of the Play": Icelandic Preschool Children Challenge Adult-Initiated Rules in Play

    ERIC Educational Resources Information Center

    Ólafsdóttir, Sara Margrét; Danby, Susan; Einarsdóttir, Jóhanna; Theobald, Maryanne

    2017-01-01

    In preschool settings, children challenge the adult-initiated rules in many ways during their play activities with peers. This ethnographic study with children aged 3-5 years was built on Corsaro's sociology of childhood construct that views children as agents and active participants in preschool society. The study is conducted in two preschools…

  11. 26 CFR 1.168(j)-1T - Questions and answers concerning tax-exempt entity leasing rules (temporary).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... same project if the buildings are constructed, under a common plan, within a reasonable time of each...-exempt use property rules? A-8. “Predominantly used” means that for more than 50 percent of the time used...,000 square feet), plus common area of 5,000 square feet. E uses the auditorium 80 percent of the time...

  12. 26 CFR 1.168(j)-1T - Questions and answers concerning tax-exempt entity leasing rules (temporary).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... same project if the buildings are constructed, under a common plan, within a reasonable time of each...-exempt use property rules? A-8. “Predominantly used” means that for more than 50 percent of the time used...,000 square feet), plus common area of 5,000 square feet. E uses the auditorium 80 percent of the time...

  13. 26 CFR 1.168(j)-1T - Questions and answers concerning tax-exempt entity leasing rules (temporary).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... same project if the buildings are constructed, under a common plan, within a reasonable time of each...-exempt use property rules? A-8. “Predominantly used” means that for more than 50 percent of the time used...,000 square feet), plus common area of 5,000 square feet. E uses the auditorium 80 percent of the time...

  14. Rule Extracting based on MCG with its Application in Helicopter Power Train Fault Diagnosis

    NASA Astrophysics Data System (ADS)

    Wang, M.; Hu, N. Q.; Qin, G. J.

    2011-07-01

    In order to extract decision rules for fault diagnosis from incomplete historical test records for knowledge-based damage assessment of helicopter power train structure. A method that can directly extract the optimal generalized decision rules from incomplete information based on GrC was proposed. Based on semantic analysis of unknown attribute value, the granule was extended to handle incomplete information. Maximum characteristic granule (MCG) was defined based on characteristic relation, and MCG was used to construct the resolution function matrix. The optimal general decision rule was introduced, with the basic equivalent forms of propositional logic, the rules were extracted and reduction from incomplete information table. Combined with a fault diagnosis example of power train, the application approach of the method was present, and the validity of this method in knowledge acquisition was proved.

  15. 26 CFR 1.883-0 - Outline of major topics.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Primarily traded. (d) Regularly traded. (1) General rule. (2) Classes of stock traded on a domestic.... (A) Related persons. (B) Investment companies. (4) Anti-abuse rule. (5) Example. (e) Substantiation...

  16. A programmable rules engine to provide clinical decision support using HTML forms.

    PubMed

    Heusinkveld, J; Geissbuhler, A; Sheshelidze, D; Miller, R

    1999-01-01

    The authors have developed a simple method for specifying rules to be applied to information on HTML forms. This approach allows clinical experts, who lack the programming expertise needed to write CGI scripts, to construct and maintain domain-specific knowledge and ordering capabilities within WizOrder, the order-entry and decision support system used at Vanderbilt Hospital. The clinical knowledge base maintainers use HTML editors to create forms and spreadsheet programs for rule entry. A test environment has been developed which uses Netscape to display forms; the production environment displays forms using an embedded browser.

  17. Constrained dipole oscillator strength distributions, sum rules, and dispersion coefficients for Br2 and BrCN

    NASA Astrophysics Data System (ADS)

    Kumar, Ashok; Thakkar, Ajit J.

    2017-03-01

    Dipole oscillator strength distributions for Br2 and BrCN are constructed from photoabsorption cross-sections combined with constraints provided by the Kuhn-Reiche-Thomas sum rule, the high-energy behavior of the dipole-oscillator-strength density and molar refractivity data when available. The distributions are used to predict dipole sum rules S (k) , mean excitation energies I (k) , and van der Waals C6 coefficients. Coupled-cluster calculations of the static dipole polarizabilities of Br2 and BrCN are reported for comparison with the values of S (- 2) extracted from the distributions.

  18. 77 FR 9733 - Business Conduct Standards for Swap Dealers and Major Swap Participants With Counterparties

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ...The Commodity Futures Trading Commission (``Commission'' or ``CFTC'') is adopting final rules to implement Section 4s(h) of the Commodity Exchange Act (``CEA'') pursuant to Section 731 of Title VII of the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010 (the ``Dodd-Frank Act''). These rules prescribe external business conduct standards for swap dealers and major swap participants.

  19. 75 FR 47519 - TRICARE: Unfortunate Sequelae From Noncovered Services in a Military Treatment Facility

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ... the Secretary, Department of Defense. ACTION: Proposed rule. SUMMARY: The Department of Defense is... significant regulatory action, defined as one that would result in an annual effect of $100 million or more on... rule is not a major rule or significant regulatory action. Public Law 104-4, Section 202, ``Unfunded...

  20. Concurrent approach for evolving compact decision rule sets

    NASA Astrophysics Data System (ADS)

    Marmelstein, Robert E.; Hammack, Lonnie P.; Lamont, Gary B.

    1999-02-01

    The induction of decision rules from data is important to many disciplines, including artificial intelligence and pattern recognition. To improve the state of the art in this area, we introduced the genetic rule and classifier construction environment (GRaCCE). It was previously shown that GRaCCE consistently evolved decision rule sets from data, which were significantly more compact than those produced by other methods (such as decision tree algorithms). The primary disadvantage of GRaCCe, however, is its relatively poor run-time execution performance. In this paper, a concurrent version of the GRaCCE architecture is introduced, which improves the efficiency of the original algorithm. A prototype of the algorithm is tested on an in- house parallel processor configuration and the results are discussed.

  1. Using Magnetic Helicity Diagnostics to Determine the Nature of Solar Active-Region Formation

    NASA Astrophysics Data System (ADS)

    Georgoulis, Manolis K.

    Employing a novel nonlinear force-free (NLFF) method that self-consistently infers instantaneous free magnetic-energy and relative magnetic-helicity budgets from single photospheric vector magnetograms, we recently constructed the magnetic energy-helicity (EH) diagram of solar active regions. The EH diagram implies dominant relative helicities of left-handed or right-handed chiralities for the great majority of active regions. The amplitude (budget) of these helicities scales monotonically with the free magnetic energy. This constructive, strongly preferential accumulation of a certain sense of magnetic helicity seems to disqualify recently proposed mechanisms relying on a largely random near-surface convection for the formation of the great majority of active regions. The existing qualitative formation mechanism for these regions remains the conventional Omega-loop emergence following a buoyant ascension from the bottom of the convection zone. However, exceptions to this rule include even eruptive active regions: NOAA AR 11283 is an obvious outlier to the EH diagram, involving significant free magnetic energy with a small relative magnetic helicity. Relying on a timeseries of vector magnetograms of this region, our methodology shows nearly canceling amounts of both senses of helicity and an overall course from a weakly left-handed to a weakly right-handed structure, in the course of which a major eruption occurs. For this and similarly behaving active regions the latest near-surface formation scenario might conceivably be employed successfully. Research partially supported by the EU Seventh Framework Programme under grant agreement No. PIRG07-GA-2010-268245 and by the European Union Social Fund (ESF) and Greek national funds through the Operational Program "Education and Lifelong Learning" of the National Strategic Reference Framework (NSRF) - Research Funding Program: Thales. Investing in knowledge society through the European Social Fund.

  2. 77 FR 30359 - Defense Federal Acquisition Regulation Supplement: New Free Trade Agreement With Colombia (DFARS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ... (see FAR 25.408). II. Discussion and Analysis This interim rule adds Colombia to the definition of...,000 for construction. Because the Colombia FTA construction threshold of $7,777,000 is the same as the... states that acquisitions that do not exceed $150,000 (with some exceptions) are automatically reserved...

  3. 10 CFR 2.402 - Separate hearings on separate issues; consolidation of proceedings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... appendix N of part 50 of this chapter for construction permits for nuclear power reactors of a type... Licenses To Construct and/or Operate Nuclear Power Plants of Identical Design at Multiple Sites § 2.402... proceedings. 2.402 Section 2.402 Energy NUCLEAR REGULATORY COMMISSION RULES OF PRACTICE FOR DOMESTIC LICENSING...

  4. 77 FR 67563 - Regulated Navigation Area-New Haven Harbor, Quinnipiac River, Mill River, New Haven, CT; Pearl...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ...; Pearl Harbor Memorial Bridge (Interstate 95) Construction AGENCY: Coast Guard, DHS. ACTION: Final rule... construction of the new Pearl Harbor Memorial Bridge, and which could be needed at other times as well. This..., call or email Petty Officer Joseph Graun, Prevention Department, U.S. Coast Guard Sector Long Island...

  5. 76 FR 58155 - Defense Federal Acquisition Regulation Supplement; Construction and Architect-Engineer Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... past performance for construction and Architect- Engineer services. On April 19, 2011, DoD published a... electronically collecting past performance data; there is no need to specify separate DoD forms to collect the... this rule other than the cost of internet access should small entities choose to comment on their past...

  6. eFSM--a novel online neural-fuzzy semantic memory model.

    PubMed

    Tung, Whye Loon; Quek, Chai

    2010-01-01

    Fuzzy rule-based systems (FRBSs) have been successfully applied to many areas. However, traditional fuzzy systems are often manually crafted, and their rule bases that represent the acquired knowledge are static and cannot be trained to improve the modeling performance. This subsequently leads to intensive research on the autonomous construction and tuning of a fuzzy system directly from the observed training data to address the knowledge acquisition bottleneck, resulting in well-established hybrids such as neural-fuzzy systems (NFSs) and genetic fuzzy systems (GFSs). However, the complex and dynamic nature of real-world problems demands that fuzzy rule-based systems and models be able to adapt their parameters and ultimately evolve their rule bases to address the nonstationary (time-varying) characteristics of their operating environments. Recently, considerable research efforts have been directed to the study of evolving Tagaki-Sugeno (T-S)-type NFSs based on the concept of incremental learning. In contrast, there are very few incremental learning Mamdani-type NFSs reported in the literature. Hence, this paper presents the evolving neural-fuzzy semantic memory (eFSM) model, a neural-fuzzy Mamdani architecture with a data-driven progressively adaptive structure (i.e., rule base) based on incremental learning. Issues related to the incremental learning of the eFSM rule base are carefully investigated, and a novel parameter learning approach is proposed for the tuning of the fuzzy set parameters in eFSM. The proposed eFSM model elicits highly interpretable semantic knowledge in the form of Mamdani-type if-then fuzzy rules from low-level numeric training data. These Mamdani fuzzy rules define the computing structure of eFSM and are incrementally learned with the arrival of each training data sample. New rules are constructed from the emergence of novel training data and obsolete fuzzy rules that no longer describe the recently observed data trends are pruned. This enables eFSM to maintain a current and compact set of Mamdani-type if-then fuzzy rules that collectively generalizes and describes the salient associative mappings between the inputs and outputs of the underlying process being modeled. The learning and modeling performances of the proposed eFSM are evaluated using several benchmark applications and the results are encouraging.

  7. Development of national standards related to the integrated safety and security of high-rise buildings

    NASA Astrophysics Data System (ADS)

    Voskresenskaya, Elena; Vorona-Slivinskaya, Lubov

    2018-03-01

    The article considers the issues of developing national standards for high-rise construction. The system of standards should provide industrial, operational, economic and terrorist safety of high-rise buildings and facilities. Modern standards of high-rise construction should set the rules for designing engineering systems of high-rise buildings, which will ensure the integrated security of buildings, increase their energy efficiency and reduce the consumption of resources in construction and operation.

  8. The Development of Symbolic Uses of Objects in Infants in a Triadic Context: A Pragmatic and Semiotic Perspective

    ERIC Educational Resources Information Center

    Palacios, Pedro; Rodríguez, Cintia

    2015-01-01

    In this study, we address the construction of the first symbolic uses of objects in contexts of triadic interaction (adult-child-object). We assume that symbolic productions are based on public rules of the use of objects previously agreed by the community. The first symbols are not rooted in any literal, evident reality, but in shared rules of…

  9. A hierarchical fuzzy rule-based approach to aphasia diagnosis.

    PubMed

    Akbarzadeh-T, Mohammad-R; Moshtagh-Khorasani, Majid

    2007-10-01

    Aphasia diagnosis is a particularly challenging medical diagnostic task due to the linguistic uncertainty and vagueness, inconsistencies in the definition of aphasic syndromes, large number of measurements with imprecision, natural diversity and subjectivity in test objects as well as in opinions of experts who diagnose the disease. To efficiently address this diagnostic process, a hierarchical fuzzy rule-based structure is proposed here that considers the effect of different features of aphasia by statistical analysis in its construction. This approach can be efficient for diagnosis of aphasia and possibly other medical diagnostic applications due to its fuzzy and hierarchical reasoning construction. Initially, the symptoms of the disease which each consists of different features are analyzed statistically. The measured statistical parameters from the training set are then used to define membership functions and the fuzzy rules. The resulting two-layered fuzzy rule-based system is then compared with a back propagating feed-forward neural network for diagnosis of four Aphasia types: Anomic, Broca, Global and Wernicke. In order to reduce the number of required inputs, the technique is applied and compared on both comprehensive and spontaneous speech tests. Statistical t-test analysis confirms that the proposed approach uses fewer Aphasia features while also presenting a significant improvement in terms of accuracy.

  10. 13 CFR 400.110 - Amendments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PROGRAM Board Procedures § 400.110 Amendments. The Board's rules in this chapter may be adopted or amended, or new rules may be adopted, only by majority vote of the Board. [65 FR 70293, Nov. 22, 2000] ...

  11. 20 CFR 404.1569 - Listing of Medical-Vocational Guidelines in appendix 2.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... factors and residual functional capacity is not the same as the corresponding criterion of a rule. In... national economy. Appendix 2 provides rules using this data reflecting major functional and vocational...

  12. Rules and construction effects in learning the argument structure of verbs.

    PubMed

    Demuth, Katherine; Machobane, Malillo; Moloi, Francina

    2003-11-01

    Theorists of language acquisition have long debated the means by which children learn the argument structure of verbs (e.g. Bowerman, 1974, 1990; Pinker, 1984, 1989; Tomasello, 1992). Central to this controversy has been the possible role of verb semantics, especially in learning which verbs undergo dative-shift alternation in languages like English. The learning problem is somewhat simplified in Bantu double object constructions, where all applicative verbs show the same order of postverbal objects. However, Bantu languages differ as to what that order is, some placing the benefactive argument first, and others placing the animate argument first. Learning the language-specific word-order restrictions on Bantu double object applicative constructions is therefore more akin to setting a parameter (cf. Hyams, 1986). This study examined 100 three- to eight-year-old children's knowledge of word order restrictions in Sesotho double object applicatives. Performance on forced choice elicited production tasks found that four-year-olds showed evidence of rule learning, although eight-year-olds had not yet attained adult levels of performance. Further investigation found lexical construction effects for three-year-olds. These findings suggest that learning the argument structure of verbs, even when lexical semantics is not involved, may be more sensitive to lexical construction effects than previously thought.

  13. Dynamic Construction Scheme for Virtualization Security Service in Software-Defined Networks

    PubMed Central

    Lin, Zhaowen; Tao, Dan; Wang, Zhenji

    2017-01-01

    For a Software Defined Network (SDN), security is an important factor affecting its large-scale deployment. The existing security solutions for SDN mainly focus on the controller itself, which has to handle all the security protection tasks by using the programmability of the network. This will undoubtedly involve a heavy burden for the controller. More devastatingly, once the controller itself is attacked, the entire network will be paralyzed. Motivated by this, this paper proposes a novel security protection architecture for SDN. We design a security service orchestration center in the control plane of SDN, and this center physically decouples from the SDN controller and constructs SDN security services. We adopt virtualization technology to construct a security meta-function library, and propose a dynamic security service composition construction algorithm based on web service composition technology. The rule-combining method is used to combine security meta-functions to construct security services which meet the requirements of users. Moreover, the RETE algorithm is introduced to improve the efficiency of the rule-combining method. We evaluate our solutions in a realistic scenario based on OpenStack. Substantial experimental results demonstrate the effectiveness of our solutions that contribute to achieve the effective security protection with a small burden of the SDN controller. PMID:28430155

  14. Dynamic Construction Scheme for Virtualization Security Service in Software-Defined Networks.

    PubMed

    Lin, Zhaowen; Tao, Dan; Wang, Zhenji

    2017-04-21

    For a Software Defined Network (SDN), security is an important factor affecting its large-scale deployment. The existing security solutions for SDN mainly focus on the controller itself, which has to handle all the security protection tasks by using the programmability of the network. This will undoubtedly involve a heavy burden for the controller. More devastatingly, once the controller itself is attacked, the entire network will be paralyzed. Motivated by this, this paper proposes a novel security protection architecture for SDN. We design a security service orchestration center in the control plane of SDN, and this center physically decouples from the SDN controller and constructs SDN security services. We adopt virtualization technology to construct a security meta-function library, and propose a dynamic security service composition construction algorithm based on web service composition technology. The rule-combining method is used to combine security meta-functions to construct security services which meet the requirements of users. Moreover, the RETE algorithm is introduced to improve the efficiency of the rule-combining method. We evaluate our solutions in a realistic scenario based on OpenStack. Substantial experimental results demonstrate the effectiveness of our solutions that contribute to achieve the effective security protection with a small burden of the SDN controller.

  15. treeman: an R package for efficient and intuitive manipulation of phylogenetic trees.

    PubMed

    Bennett, Dominic J; Sutton, Mark D; Turvey, Samuel T

    2017-01-07

    Phylogenetic trees are hierarchical structures used for representing the inter-relationships between biological entities. They are the most common tool for representing evolution and are essential to a range of fields across the life sciences. The manipulation of phylogenetic trees-in terms of adding or removing tips-is often performed by researchers not just for reasons of management but also for performing simulations in order to understand the processes of evolution. Despite this, the most common programming language among biologists, R, has few class structures well suited to these tasks. We present an R package that contains a new class, called TreeMan, for representing the phylogenetic tree. This class has a list structure allowing phylogenetic trees to be manipulated more efficiently. Computational running times are reduced because of the ready ability to vectorise and parallelise methods. Development is also improved due to fewer lines of code being required for performing manipulation processes. We present three use cases-pinning missing taxa to a supertree, simulating evolution with a tree-growth model and detecting significant phylogenetic turnover-that demonstrate the new package's speed and simplicity.

  16. 7 CFR 1753.4 - Major and minor construction.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 11 2011-01-01 2011-01-01 false Major and minor construction. 1753.4 Section 1753.4... AGRICULTURE TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES General § 1753.4 Major and minor... H (OMB control number 0572-0062). The requirements and procedures for minor construction are...

  17. 7 CFR 1753.4 - Major and minor construction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Major and minor construction. 1753.4 Section 1753.4... AGRICULTURE TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES General § 1753.4 Major and minor... H (OMB control number 0572-0062). The requirements and procedures for minor construction are...

  18. Using Nonprinciple Rays to Form Images in Geometrical Optics

    NASA Astrophysics Data System (ADS)

    Marx, Jeff; Mian, Shabbir

    2015-11-01

    Constructing ray diagrams to locate the image of an object formed by thin lenses and mirrors is a staple of many introductory physics courses at the high school and college levels, and has been the subject of some pedagogy-related articles. Our review of textbooks distributed in the United States suggests that the singular approach involves drawing principle rays to locate an object's image. We were pleasantly surprised to read an article in this journal by Suppapittayaporn et al. in which they use an alternative method to construct rays for thin lenses based on a "tilted principle axis" (TPA). In particular, we were struck by the generality of the approach (a single rule for tracing rays as compared to the typical two or three rules), and how it could help students more easily tackle challenging situations, such as multi-lens systems and occluded lenses, where image construction using principle rays may be impractical. In this paper, we provide simple "proofs" for this alternative approach for the case of thin lenses and single refracting surfaces.

  19. Simplification rules for birdtrack operators

    NASA Astrophysics Data System (ADS)

    Alcock-Zeilinger, J.; Weigert, H.

    2017-05-01

    This paper derives a set of easy-to-use tools designed to simplify calculations with birdtrack operators comprised of symmetrizers and antisymmetrizers. In particular, we present cancellation rules allowing one to shorten the birdtrack expressions of operators and propagation rules identifying the circumstances under which it is possible to propagate symmetrizers past antisymmetrizers and vice versa. We exhibit the power of these simplification rules by means of a short example in which we apply the tools derived in this paper on a typical operator that can be encountered in the representation theory of 𝖲𝖴 (N ) over the product space V⊗m. These rules form the basis for the construction of compact Hermitian Young projection operators and their transition operators addressed in companion papers [J. Alcock-Zeilinger and H. Weigert, "Compact Hermitian Young projection operators," e-print arXiv:1610.10088 [math-ph] and J. Alcock-Zeilinger and H. Weigert, "Transition operators," e-print arXiv:1610.08802 [math-ph

  20. Greenhouse Gas Emissions from Educational Facilities and the EPA Greenhouse Gas Reporting Rule: Actions You Need to Take Now

    ERIC Educational Resources Information Center

    Wurmbrand, Mitchell M.; Klotz, Thomas C.

    2010-01-01

    On September 22, 2009, The United States Environmental Protection Agency (EPA) issued its final rule on greenhouse gas (GHG) emission reporting. The informational literature that EPA has published to support the rule clearly states that EPA believes the vast majority of smaller GHG-emitting facilities, such as educational facilities, will not be…

  1. Erosion of the At-Will Rule and Freedom of Communication in Private Sector Organizations.

    ERIC Educational Resources Information Center

    Sanders, Wayne

    The "at-will" rule in American law is defined as the right of a private sector employer to dismiss an employee without a contract for virtually any reason. The rule has thrived since the nineteenth century and is still a major factor in the employer-employee relationship. However, recent court decisions have fashioned common law…

  2. 78 FR 73472 - Defense Federal Acquisition Regulation Supplement: Application of Certain Clauses to Acquisitions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ... 252.211-7008, Use of Government-Assigned Serial Numbers, and DFARS 252.232-7006, Wide Area WorkFlow... harmonizing rules, and of promoting flexibility. This is not a significant regulatory action and, therefore... September 30, 1993. This rule is not a major rule under 5 U.S.C. 804. III. Regulatory Flexibility Act DoD...

  3. The knowledge and attitudes of midwives regarding legal and religious commandments on induced abortion and their relationship with some demographic characteristics.

    PubMed

    Afhami, Narges; Bahadoran, Parvin; Taleghani, Hamid Reza; Nekuei, Nafisehsadat

    2016-01-01

    Induced abortion is an important medical issue. Knowledge and attitude of midwives regarding legal and religious commandments on induced abortion can be useful in confronting this issue. The aim of this study was to assess the knowledge and attitudes of midwives of Isfahan regarding these rules and to find their relationship with demographic characteristics. This was a cross-sectional, descriptive, and analytical study. The study participants consisted of 189 midwives working in hospitals, health centers, private gynecology clinics, and university. Random quota sampling method was used. Data were collected using a researcher-made questionnaire. Data were analyzed using mean, frequency distribution tables, Pearson correlation, and Spearman's coefficient. For all tests, an error of less than 0.05 was considered. The majority of the participants had extremely low to moderate (73%) knowledge about the subject of the study. Their attitudes toward effective implementation of these rules were mostly extremely weak to moderate (68.72%). No correlation was observed between knowledge, age, work experience, and education. However, there was a relationship between the level of knowledge about these rules and the location of service. There was no significant correlation between attitude and demographic characteristics. Due to less knowledge of the midwives and their low attitude score in this regard, training them, improving their attitude toward these issues, and effective implementation of these laws are necessary. Therefore, by identifying the factors affecting the formation of attitudes and the level of knowledge, more constructive proceedings can be taken to promote them.

  4. Innate and genetic nature of circadian rhythms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ehret, C.F.

    1979-01-01

    The field of Circadian Cybernetics is presented as a major new integrating discipline that deals with biological time constants in the temporal range from minutes to days. The essential generalizations that give the field strong predictive power are presented in the form of 3 sets of rules: (1) The Mode Rules; (2) The Period Rules; and (3) The Phase Rules. Within this context the innate and phylogenetically ubiquitous nature of circadian oscillations is comprehended, along with their responses to a wide variety environmental stimuli.

  5. Context recognition for a hyperintensional inference machine

    NASA Astrophysics Data System (ADS)

    Duží, Marie; Fait, Michal; Menšík, Marek

    2017-07-01

    The goal of this paper is to introduce the algorithm of context recognition in the functional programming language TIL-Script, which is a necessary condition for the implementation of the TIL-Script inference machine. The TIL-Script language is an operationally isomorphic syntactic variant of Tichý's Transparent Intensional Logic (TIL). From the formal point of view, TIL is a hyperintensional, partial, typed λ-calculus with procedural semantics. Hyperintensional, because TIL λ-terms denote procedures (defined as TIL constructions) producing set-theoretic functions rather than the functions themselves; partial, because TIL is a logic of partial functions; and typed, because all the entities of TIL ontology, including constructions, receive a type within a ramified hierarchy of types. These features make it possible to distinguish three levels of abstraction at which TIL constructions operate. At the highest hyperintensional level the object to operate on is a construction (though a higher-order construction is needed to present this lower-order construction as an object of predication). At the middle intensional level the object to operate on is the function presented, or constructed, by a construction, while at the lowest extensional level the object to operate on is the value (if any) of the presented function. Thus a necessary condition for the development of an inference machine for the TIL-Script language is recognizing a context in which a construction occurs, namely extensional, intensional and hyperintensional context, in order to determine the type of an argument at which a given inference rule can be properly applied. As a result, our logic does not flout logical rules of extensional logic, which makes it possible to develop a hyperintensional inference machine for the TIL-Script language.

  6. Attending to the Grammatical Errors of Students Using Constructive Teaching and Learning Activities

    ERIC Educational Resources Information Center

    Wornyo, Albert Agbesi

    2016-01-01

    This study was a classroom-based action research. In this study, constructive teaching and learning activities were used to help learners improve on their grammar and usage with a focus on how to help them internalize subject verb agreement rules. The purpose of the research was to assist learners to improve upon their performance in grammar and…

  7. 27 CFR 53.96 - Constructive sale price; special rule for arm's-length sales.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... as not being at retail or to retailers, or both, if the industry dollar volume of sales which are at retail or to retailers, or both, is less than half the total industry dollar volume of sales at all... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Constructive sale price...

  8. From Ought to Is: A Neo-Marxist Perspective on the Use and Misuse of the Culture Construct.

    ERIC Educational Resources Information Center

    Baumrind, Diana

    1998-01-01

    Presents a neo-Marxist perspective on morality, showing how it pertains to the use and misuse of the culture construct. Explains the standpoint concept, and identifies issues central to morality. Maintains that moral beliefs are grounded in cultural contexts, arguing that the dominant morality in a culture justifies ruling class interests, and…

  9. 10 CFR 2.604 - Notice of hearing on application for early review of site suitability issues in construction...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Notice of hearing on application for early review of site... AGENCY RULES OF PRACTICE AND PROCEDURE Additional Procedures Applicable to Early Partial Decisions on... Early Partial Decisions on Site Suitability-Construction Permit § 2.604 Notice of hearing on application...

  10. 10 CFR 2.604 - Notice of hearing on application for early review of site suitability issues in construction...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Notice of hearing on application for early review of site... AGENCY RULES OF PRACTICE AND PROCEDURE Additional Procedures Applicable to Early Partial Decisions on... Early Partial Decisions on Site Suitability-Construction Permit § 2.604 Notice of hearing on application...

  11. 76 FR 5158 - Notice of Public Information Collection(s) Being Submitted for Review and Approval to the Office...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... Authority to Construct or Make Changes in a Low Power TV, TV Translator, or TV Booster Station, FCC Form 346... construct or make changes in a Low Power Television, TV Translator, or TV Booster broadcast station. On..., Television Translator, and Television Booster Stations and to Amend Rules for Digital Class A Television...

  12. Programmable Potentials: Approximate N-body potentials from coarse-level logic.

    PubMed

    Thakur, Gunjan S; Mohr, Ryan; Mezić, Igor

    2016-09-27

    This paper gives a systematic method for constructing an N-body potential, approximating the true potential, that accurately captures meso-scale behavior of the chemical or biological system using pairwise potentials coming from experimental data or ab initio methods. The meso-scale behavior is translated into logic rules for the dynamics. Each pairwise potential has an associated logic function that is constructed using the logic rules, a class of elementary logic functions, and AND, OR, and NOT gates. The effect of each logic function is to turn its associated potential on and off. The N-body potential is constructed as linear combination of the pairwise potentials, where the "coefficients" of the potentials are smoothed versions of the associated logic functions. These potentials allow a potentially low-dimensional description of complex processes while still accurately capturing the relevant physics at the meso-scale. We present the proposed formalism to construct coarse-grained potential models for three examples: an inhibitor molecular system, bond breaking in chemical reactions, and DNA transcription from biology. The method can potentially be used in reverse for design of molecular processes by specifying properties of molecules that can carry them out.

  13. Programmable Potentials: Approximate N-body potentials from coarse-level logic

    NASA Astrophysics Data System (ADS)

    Thakur, Gunjan S.; Mohr, Ryan; Mezić, Igor

    2016-09-01

    This paper gives a systematic method for constructing an N-body potential, approximating the true potential, that accurately captures meso-scale behavior of the chemical or biological system using pairwise potentials coming from experimental data or ab initio methods. The meso-scale behavior is translated into logic rules for the dynamics. Each pairwise potential has an associated logic function that is constructed using the logic rules, a class of elementary logic functions, and AND, OR, and NOT gates. The effect of each logic function is to turn its associated potential on and off. The N-body potential is constructed as linear combination of the pairwise potentials, where the “coefficients” of the potentials are smoothed versions of the associated logic functions. These potentials allow a potentially low-dimensional description of complex processes while still accurately capturing the relevant physics at the meso-scale. We present the proposed formalism to construct coarse-grained potential models for three examples: an inhibitor molecular system, bond breaking in chemical reactions, and DNA transcription from biology. The method can potentially be used in reverse for design of molecular processes by specifying properties of molecules that can carry them out.

  14. Programmable Potentials: Approximate N-body potentials from coarse-level logic

    PubMed Central

    Thakur, Gunjan S.; Mohr, Ryan; Mezić, Igor

    2016-01-01

    This paper gives a systematic method for constructing an N-body potential, approximating the true potential, that accurately captures meso-scale behavior of the chemical or biological system using pairwise potentials coming from experimental data or ab initio methods. The meso-scale behavior is translated into logic rules for the dynamics. Each pairwise potential has an associated logic function that is constructed using the logic rules, a class of elementary logic functions, and AND, OR, and NOT gates. The effect of each logic function is to turn its associated potential on and off. The N-body potential is constructed as linear combination of the pairwise potentials, where the “coefficients” of the potentials are smoothed versions of the associated logic functions. These potentials allow a potentially low-dimensional description of complex processes while still accurately capturing the relevant physics at the meso-scale. We present the proposed formalism to construct coarse-grained potential models for three examples: an inhibitor molecular system, bond breaking in chemical reactions, and DNA transcription from biology. The method can potentially be used in reverse for design of molecular processes by specifying properties of molecules that can carry them out. PMID:27671683

  15. Range Safety for an Autonomous Flight Safety System

    NASA Technical Reports Server (NTRS)

    Lanzi, Raymond J.; Simpson, James C.

    2010-01-01

    The Range Safety Algorithm software encapsulates the various constructs and algorithms required to accomplish Time Space Position Information (TSPI) data management from multiple tracking sources, autonomous mission mode detection and management, and flight-termination mission rule evaluation. The software evaluates various user-configurable rule sets that govern the qualification of TSPI data sources, provides a prelaunch autonomous hold-launch function, performs the flight-monitoring-and-termination functions, and performs end-of-mission safing

  16. Myrtenal, a controversial molecule for the proper application of the CIP Sequence Rule for multiple bonds.

    PubMed

    Zepeda, L Gerardo; Burgueño-Tapia, Eleuterio; Joseph-Nathan, Pedro

    2011-04-01

    This communication highlights the need of building hierarchical digraphs for the unequivocal assignment of stereochemical descriptors of (-)-myrtenal, a naturally-occurring oxygenated monoterpene whose absolute configuration (AC) is sometimes misrepresented in its structural formulae. Differentiation between duplicated atoms and phantom atoms for the proper application of the sequence rules is shown to be an essential step to get a proper construction of hierarchical digraphs.

  17. Fuzzy Rule Suram for Wood Drying

    NASA Astrophysics Data System (ADS)

    Situmorang, Zakarias

    2017-12-01

    Implemented of fuzzy rule must used a look-up table as defuzzification analysis. Look-up table is the actuator plant to doing the value of fuzzification. Rule suram based of fuzzy logic with variables of weather is temperature ambient and humidity ambient, it implemented for wood drying process. The membership function of variable of state represented in error value and change error with typical map of triangle and map of trapezium. Result of analysis to reach 4 fuzzy rule in 81 conditions to control the output system can be constructed in a number of way of weather and conditions of air. It used to minimum of the consumption of electric energy by heater. One cycle of schedule drying is a serial of condition of chamber to process as use as a wood species.

  18. A rule-based automatic sleep staging method.

    PubMed

    Liang, Sheng-Fu; Kuo, Chin-En; Hu, Yu-Han; Cheng, Yu-Shian

    2012-03-30

    In this paper, a rule-based automatic sleep staging method was proposed. Twelve features including temporal and spectrum analyses of the EEG, EOG, and EMG signals were utilized. Normalization was applied to each feature to eliminating individual differences. A hierarchical decision tree with fourteen rules was constructed for sleep stage classification. Finally, a smoothing process considering the temporal contextual information was applied for the continuity. The overall agreement and kappa coefficient of the proposed method applied to the all night polysomnography (PSG) of seventeen healthy subjects compared with the manual scorings by R&K rules can reach 86.68% and 0.79, respectively. This method can integrate with portable PSG system for sleep evaluation at-home in the near future. Copyright © 2012 Elsevier B.V. All rights reserved.

  19. Masses of Open-Flavour Heavy-Light Hybrids from QCD Sum Rules

    NASA Astrophysics Data System (ADS)

    Ho, Jason; Harnett, Derek; Steele, Tom

    2017-01-01

    Our current understanding of the strong interaction (QCD) permits the construction of colour singlet states with novel structures that do not fit within the traditional quark model, including hybrid mesons. To date, though other exotic structures such as pentaquark and tetraquark states have been confirmed, no unambiguous hybrid meson signals have been observed. However, with data collection at the GlueX experiment ongoing and with the construction of the PANDA experiment at FAIR, the opportunity to observe hybrid states has never been better. As theoretical calculations are a necessary piece for the identification of any observed experimental resonance, we present our mass predictions of heavy-light open-flavour hybrid mesons using QCD Laplace sum-rules for all scalar and vector JP channels, and including non-perturbative condensate contributions up to six-dimensions.

  20. Transformation of PRT6 RNAi construct into tomato (Solanum lycopersicum) cv. Micro-Tom

    NASA Astrophysics Data System (ADS)

    Suka, Intan Elya; Chew, Bee Lynn; Goh, Hoe-Han; Isa, Nurulhikma Md

    2018-04-01

    PROTEOLYSIS 6 plays major role in the N-end rule pathway as N-recognin which functions as E3 ligase enzyme. It mediates ubiquitin processes that lead to degradation of unstable substrate protein. The aim of the current study is to transform the PRT6 gene into tomato (Solanum lycopersicum) from the cultivar Micro-Tom and to investigate its function in regulating ripening in tomato fruits. The PRT6_RNAi construct was successfully transformed into Agrobacterium C58 via heat shock method and transformed into seven days old cotyledon explants. Factors affecting transformation efficiency such as co-cultivation time and type of plant growth regulator combination were evaluated. Results from this study found that pre-cultured cotyledons from seven days old seedlings incubated for 2 days in co-cultivation medium increased shoot regeneration. Plant growth hormones zeatin combine with auxin produced a higher number of callus formation but lower shoot proliferation and transformation frequency compared to treatments of single plant hormone in the selection medium. Polymerase chain reaction (PCR) was performed on the regenerated shoots to confirm the integration of PRT6 fragment into the genome of transgenic plants. Based on PCR analysis, all putative shoots were positive transformants.

  1. A programmable rules engine to provide clinical decision support using HTML forms.

    PubMed Central

    Heusinkveld, J.; Geissbuhler, A.; Sheshelidze, D.; Miller, R.

    1999-01-01

    The authors have developed a simple method for specifying rules to be applied to information on HTML forms. This approach allows clinical experts, who lack the programming expertise needed to write CGI scripts, to construct and maintain domain-specific knowledge and ordering capabilities within WizOrder, the order-entry and decision support system used at Vanderbilt Hospital. The clinical knowledge base maintainers use HTML editors to create forms and spreadsheet programs for rule entry. A test environment has been developed which uses Netscape to display forms; the production environment displays forms using an embedded browser. Images Figure 1 PMID:10566470

  2. A new vapor-liquid equilibrium apparatus for hydrogen fluoride containing systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jongcheon Lee; Hwayong Kim; Jong Sung Lim

    1996-12-31

    A new circulating type apparatus has been constructed to obtain reliable equilibrium PTxy data for hydrogen fluoride (HF) containing system. Equilibrium cell with Pyrex windows protected by Teflon PFA sheets to prevent the corrosion was used. Isothermal vapor-liquid equilibrium data for the 1,1-difluoroethane (HFC-152a) + HF system at 288.23 and 298.35 K were obtained, and compared with PTx measurement results. Experimental data were correlated using Lencka and Anderko equation of state for HF with the Wong-Sandler mixing rule as well as the van der Waals one fluid mixing rule. The Wong-Sandler mixing rule gives better results. 5 refs., 3 figs.

  3. 20 CFR 220.134 - Medical-vocational guidelines in appendix 2 of this part.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... vocational factors and residual functional capacity is not the same as the corresponding criterion of a rule... economy. Appendix 2 of this part provides rules using this data reflecting major functional and vocational...

  4. 45 CFR 1309.52 - Procurement procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START PROGRAM HEAD START FACILITIES PURCHASE, MAJOR RENOVATION AND CONSTRUCTION Construction and Major Renovation § 1309.52 Procurement procedures. (a) All facility construction and major renovation transactions...

  5. 45 CFR 1309.52 - Procurement procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START PROGRAM HEAD START FACILITIES PURCHASE, MAJOR RENOVATION AND CONSTRUCTION Construction and Major Renovation § 1309.52 Procurement procedures. (a) All facility construction and major renovation transactions...

  6. Constructing a Bayesian network model for improving safety behavior of employees at workplaces.

    PubMed

    Mohammadfam, Iraj; Ghasemi, Fakhradin; Kalatpour, Omid; Moghimbeigi, Abbas

    2017-01-01

    Unsafe behavior increases the risk of accident at workplaces and needs to be managed properly. The aim of the present study was to provide a model for managing and improving safety behavior of employees using the Bayesian networks approach. The study was conducted in several power plant construction projects in Iran. The data were collected using a questionnaire composed of nine factors, including management commitment, supporting environment, safety management system, employees' participation, safety knowledge, safety attitude, motivation, resource allocation, and work pressure. In order for measuring the score of each factor assigned by a responder, a measurement model was constructed for each of them. The Bayesian network was constructed using experts' opinions and Dempster-Shafer theory. Using belief updating, the best intervention strategies for improving safety behavior also were selected. The result of the present study demonstrated that the majority of employees do not tend to consider safety rules, regulation, procedures and norms in their behavior at the workplace. Safety attitude, safety knowledge, and supporting environment were the best predictor of safety behavior. Moreover, it was determined that instantaneous improvement of supporting environment and employee participation is the best strategy to reach a high proportion of safety behavior at the workplace. The lack of a comprehensive model that can be used for explaining safety behavior was one of the most problematic issues of the study. Furthermore, it can be concluded that belief updating is a unique feature of Bayesian networks that is very useful in comparing various intervention strategies and selecting the best one form them. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Ontogenetic constraints on foraminiferal test construction.

    PubMed

    Caromel, Aude G M; Schmidt, Daniela N; Rayfield, Emily J

    2017-05-01

    Developmental processes represent one of the main constraints on the generation of adult form. Determining how constructional and energetic demands operate throughout growth is es-sential to understanding fundamental growth rules and trade-offs that define the framework within which new species originate. In organisms producing spiral shells, coiling patterns can inform on the constructional constraints acting throughout development that dictated the diversification of forms within a group. Here, we use Synchrotron radiation X-Ray tomographic microscopy (SRXTM) reconstructions of eight planktic foraminifera repre-sentative of the major morphotypic groups to determine disparity of coiling patterns by measuring Raupian parameters. The results show that foraminifera are a morphologically highly conservative group, exploiting a limited range of poten-tial coiling patterns. Very similar coiling patterns during early ontogeny, regardless of species, point toward strong constraints in early ontogeny and to common develop-mental processes acting across all morphogroups. Dispersion and lateral displacement of taxa in morphospace are limited to the adult stage. Accretion with low translation down the coiling axis in juveniles may maximize lateral growth and metabolic efficiency in light of costly calcification. Increased translation in the adult stages allows growth to accommo-date new chamber shapes, mediated by changes in aperture location and the site of accretion over ontogeny. These constructional constraints, and the accretion of a small number of discrete chambers, limit the potential for novel forms within the foraminifera compared to other groups of coiling organisms and may explain the repeated evolution of similar morphotypes throughout the evolutionary history of the group. © 2017 Wiley Periodicals, Inc.

  8. [Geo-spectrum characteristics of land use change in Jiangsu Province, China.

    PubMed

    Lyu, Xiao; Shi, Yang Yang; Huang, Xian Jin; Sun, Xiao Fang; Miao, Zhi Wei

    2016-04-22

    This paper studied the spatial-temporal characteristics and rules of land use change in Jiangsu Province using theories and methods of geo-spectrum. Based on the land use data translated from remote sensing images of 1990, 2000 and 2010, we synthesized the geo-spectrum of the mode of arable land use change and that of land use change in two corresponding phases, 1990-2000 and 2000-2010, in Jiangsu using ArcGIS 10.0. The results showed that in the phase of 1990-2000, the major characteristics of land use change were swaps between the geo-spectrum unit of arable land and urban-rural construction land, arable land and water body, and arable land and grassland. Specifically, the patterns of "arable land → urban-rural construction land" and "arable land→ water body" were highly significant. We also found the reduction of arable land area and the concentration of its spatial distribution. In the phase of 2000-2010, the "arable land → urban-rural construction land" pattern was still the most salient characteristic. In addition, the patterns of "grassland → water body" and "urban-rural construction land → water body" became more spatially concentrated and tended to expand. Compared with the previous phase, the area of the land use in the phase of 2000-2010 had been changed expanded and became more scattered. Overall, the geo-spectrum of arable land use change in Jiangsu was mainly shaped by the anaphase change type and partially by the prophase change type, with a tiny influence of the repeated and continuous change.

  9. A simple diagnostic model for ruling out pneumoconiosis among construction workers.

    PubMed

    Suarthana, Eva; Moons, Karel G M; Heederik, Dick; Meijer, Evert

    2007-09-01

    Construction workers exposed to silica-containing dust are at risk of developing silicosis even at low exposure levels. Health surveillance among these workers is commonly advised but the exact diagnostic work-up is not specified and therefore may result in unnecessary chest x ray investigations. To develop a simple diagnostic model to estimate the probability of an individual worker having pneumoconiosis from questionnaire and spirometry results, in order to accurately rule out workers without pneumoconiosis. The study was performed using cross-sectional data of 1291 Dutch natural stone and construction workers with potentially high quartz dust exposure. A multivariable logistic regression model was developed using chest x ray with ILO profusion category > or =1/1 as the reference standard. The model's calibration was evaluated with the Hosmer-Lemeshow test; the discriminative ability was determined by calculating the area under the receiver operating characteristic curve (ROC area). Internal validity of the final model was assessed by a bootstrapping procedure. For clinical application, the diagnostic model was transformed into an easy-to-use score chart. Age 40 years or older, current smoker, high-exposure job, working 15 years or longer in the construction industry, "feeling unhealthy" and FEV1 were independent predictors in the diagnostic model. The model showed good calibration (a non-significant Hosmer-Lemeshow test) and discriminative ability (ROC area 0.81, 95% CI 0.74 to 0.85). Internal validity was reasonable; the optimism corrected ROC area was 0.76. By using a cut-off point with a high negative predictive value the occupational physician can efficiently detect a large proportion of workers with a low probability of having pneumoconiosis and exclude them from unnecessary x ray investigations. This diagnostic model is an efficient and effective instrument to rule out pneumoconiosis among construction workers. Its use in health surveillance among these workers can reduce the number of redundant x ray investigations.

  10. Mental health nurses' experiences of managing work-related emotions through supervision.

    PubMed

    MacLaren, Jessica; Stenhouse, Rosie; Ritchie, Deborah

    2016-10-01

    The aim of this study was to explore emotion cultures constructed in supervision and consider how supervision functions as an emotionally safe space promoting critical reflection. Research published between 1995-2015 suggests supervision has a positive impact on nurses' emotional well-being, but there is little understanding of the processes involved in this and how styles of emotion interaction are established in supervision. A narrative approach was used to investigate mental health nurses' understandings and experiences of supervision. Eight semi-structured interviews were conducted with community mental health nurses in the UK during 2011. Analysis of audio data used features of speech to identify narrative discourse and illuminate meanings. A topic-centred analysis of interview narratives explored discourses shared between the participants. This supported the identification of feeling rules in participants' narratives and the exploration of the emotion context of supervision. Effective supervision was associated with three feeling rules: safety and reflexivity; staying professional; managing feelings. These feeling rules allowed the expression and exploration of emotions, promoting critical reflection. A contrast was identified between the emotion culture of supervision and the nurses' experience of their workplace cultures as requiring the suppression of difficult emotions. Despite this, contrast supervision functioned as an emotion micro-culture with its own distinctive feeling rules. The analytical construct of feeling rules allows us to connect individual emotional experiences to shared normative discourses, highlighting how these shape emotional processes taking place in supervision. This understanding supports an explanation of how supervision may positively influence nurses' emotion management and perhaps reduce burnout. © 2016 John Wiley & Sons Ltd.

  11. 7 CFR 1703.302 - Definitions and rules of construction.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... in making loans, operating on a self-sustaining basis to the extent practicable (section 401, RE Act..., product or service improvement, feasibility studies, environmental studies, and similar activities that...

  12. 7 CFR 1703.302 - Definitions and rules of construction.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... in making loans, operating on a self-sustaining basis to the extent practicable (section 401, RE Act..., product or service improvement, feasibility studies, environmental studies, and similar activities that...

  13. Anxiety Evokes Hypofrontality and Disrupts Rule-Relevant Encoding by Dorsomedial Prefrontal Cortex Neurons.

    PubMed

    Park, Junchol; Wood, Jesse; Bondi, Corina; Del Arco, Alberto; Moghaddam, Bita

    2016-03-16

    Anxiety is a debilitating symptom of most psychiatric disorders, including major depression, post-traumatic stress disorder, schizophrenia, and addiction. A detrimental aspect of anxiety is disruption of prefrontal cortex (PFC)-mediated executive functions, such as flexible decision making. Here we sought to understand how anxiety modulates PFC neuronal encoding of flexible shifting between behavioral strategies. We used a clinically substantiated anxiogenic treatment to induce sustained anxiety in rats and recorded from dorsomedial PFC (dmPFC) and orbitofrontal cortex (OFC) neurons while they were freely moving in a home cage and while they performed a PFC-dependent task that required flexible switches between rules in two distinct perceptual dimensions. Anxiety elicited a sustained background "hypofrontality" in dmPFC and OFC by reducing the firing rate of spontaneously active neuronal subpopulations. During task performance, the impact of anxiety was subtle, but, consistent with human data, behavior was selectively impaired when previously correct conditions were presented as conflicting choices. This impairment was associated with reduced recruitment of dmPFC neurons that selectively represented task rules at the time of action. OFC rule representation was not affected by anxiety. These data indicate that a neural substrate of the decision-making deficits in anxiety is diminished dmPFC neuronal encoding of task rules during conflict-related actions. Given the translational relevance of the model used here, the data provide a neuronal encoding mechanism for how anxiety biases decision making when the choice involves overcoming a conflict. They also demonstrate that PFC encoding of actions, as opposed to cues or outcome, is especially vulnerable to anxiety. A debilitating aspect of anxiety is its impact on decision making and flexible control of behavior. These cognitive constructs depend on proper functioning of the prefrontal cortex (PFC). Understanding how anxiety affects PFC encoding of cognitive events is of great clinical and evolutionary significance. Using a clinically valid experimental model, we find that, under anxiety, decision making may be skewed by salient and conflicting environmental stimuli at the expense of flexible top-down guided choices. We also find that anxiety suppresses spontaneous activity of PFC neurons, and weakens encoding of task rules by dorsomedial PFC neurons. These data provide a neuronal encoding scheme for how anxiety disengages PFC during decision making. Copyright © 2016 the authors 0270-6474/16/363322-14$15.00/0.

  14. Simulation-based model checking approach to cell fate specification during Caenorhabditis elegans vulval development by hybrid functional Petri net with extension.

    PubMed

    Li, Chen; Nagasaki, Masao; Ueno, Kazuko; Miyano, Satoru

    2009-04-27

    Model checking approaches were applied to biological pathway validations around 2003. Recently, Fisher et al. have proved the importance of model checking approach by inferring new regulation of signaling crosstalk in C. elegans and confirming the regulation with biological experiments. They took a discrete and state-based approach to explore all possible states of the system underlying vulval precursor cell (VPC) fate specification for desired properties. However, since both discrete and continuous features appear to be an indispensable part of biological processes, it is more appropriate to use quantitative models to capture the dynamics of biological systems. Our key motivation of this paper is to establish a quantitative methodology to model and analyze in silico models incorporating the use of model checking approach. A novel method of modeling and simulating biological systems with the use of model checking approach is proposed based on hybrid functional Petri net with extension (HFPNe) as the framework dealing with both discrete and continuous events. Firstly, we construct a quantitative VPC fate model with 1761 components by using HFPNe. Secondly, we employ two major biological fate determination rules - Rule I and Rule II - to VPC fate model. We then conduct 10,000 simulations for each of 48 sets of different genotypes, investigate variations of cell fate patterns under each genotype, and validate the two rules by comparing three simulation targets consisting of fate patterns obtained from in silico and in vivo experiments. In particular, an evaluation was successfully done by using our VPC fate model to investigate one target derived from biological experiments involving hybrid lineage observations. However, the understandings of hybrid lineages are hard to make on a discrete model because the hybrid lineage occurs when the system comes close to certain thresholds as discussed by Sternberg and Horvitz in 1986. Our simulation results suggest that: Rule I that cannot be applied with qualitative based model checking, is more reasonable than Rule II owing to the high coverage of predicted fate patterns (except for the genotype of lin-15ko; lin-12ko double mutants). More insights are also suggested. The quantitative simulation-based model checking approach is a useful means to provide us valuable biological insights and better understandings of biological systems and observation data that may be hard to capture with the qualitative one.

  15. 12 CFR 723.21 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... commercial endeavor with the borrower. Construction or development loan is a financing arrangement for...; or similar uses. Construction or development loan includes a financing arrangement for the major... the major renovation or development or is a major expansion of its current use. Construction or...

  16. 12 CFR 723.21 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... commercial endeavor with the borrower. Construction or development loan is a financing arrangement for...; or similar uses. Construction or development loan includes a financing arrangement for the major... the major renovation or development or is a major expansion of its current use. Construction or...

  17. 12 CFR 723.21 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... commercial endeavor with the borrower. Construction or development loan is a financing arrangement for...; or similar uses. Construction or development loan includes a financing arrangement for the major... the major renovation or development or is a major expansion of its current use. Construction or...

  18. 12 CFR 723.21 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... commercial endeavor with the borrower. Construction or development loan is a financing arrangement for...; or similar uses. Construction or development loan includes a financing arrangement for the major... the major renovation or development or is a major expansion of its current use. Construction or...

  19. 12 CFR 723.21 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... commercial endeavor with the borrower. Construction or development loan is a financing arrangement for...; or similar uses. Construction or development loan includes a financing arrangement for the major... the major renovation or development or is a major expansion of its current use. Construction or...

  20. Optimizing the Replication of Multi-Quality Web Applications Using ACO and WoLF

    DTIC Science & Technology

    2006-09-14

    bipartite graph in both directions as they construct solutions, pheromone is used for traversing from one side of the bipartite graph to the other and back...27 3.1.3 Transitioning From 〈d, q〉 pairs to Servers. . . . . 29 3.1.4 Pheromone Update Rule . . . . . . . . . . . . . . 30 vi Page 3.2 WoLFAntDA: A...35 3.2.6 Pheromone Update Rule . . . . . . . . . . . . . . 36 3.2.7 Policy Updates . . . . . . . . . . . . . . . . . . . 36 3.3 The Server-Filling

  1. Treatment of CHP in LEED® for Building Design and Construction: New Construction and Major Renovations

    EPA Pesticide Factsheets

    This factsheet introduces CHP and its benefits to architects and engineers, and summarizes how CHP is treated under the LEED® for Building Design and Construction: New Construction and Major Renovations (LEED BD+C: New Construction) rating system.

  2. Developing a reversible rapid coordinate transformation model for the cylindrical projection

    NASA Astrophysics Data System (ADS)

    Ye, Si-jing; Yan, Tai-lai; Yue, Yan-li; Lin, Wei-yan; Li, Lin; Yao, Xiao-chuang; Mu, Qin-yun; Li, Yong-qin; Zhu, De-hai

    2016-04-01

    Numerical models are widely used for coordinate transformations. However, in most numerical models, polynomials are generated to approximate "true" geographic coordinates or plane coordinates, and one polynomial is hard to make simultaneously appropriate for both forward and inverse transformations. As there is a transformation rule between geographic coordinates and plane coordinates, how accurate and efficient is the calculation of the coordinate transformation if we construct polynomials to approximate the transformation rule instead of "true" coordinates? In addition, is it preferable to compare models using such polynomials with traditional numerical models with even higher exponents? Focusing on cylindrical projection, this paper reports on a grid-based rapid numerical transformation model - a linear rule approximation model (LRA-model) that constructs linear polynomials to approximate the transformation rule and uses a graticule to alleviate error propagation. Our experiments on cylindrical projection transformation between the WGS 84 Geographic Coordinate System (EPSG 4326) and the WGS 84 UTM ZONE 50N Plane Coordinate System (EPSG 32650) with simulated data demonstrate that the LRA-model exhibits high efficiency, high accuracy, and high stability; is simple and easy to use for both forward and inverse transformations; and can be applied to the transformation of a large amount of data with a requirement of high calculation efficiency. Furthermore, the LRA-model exhibits advantages in terms of calculation efficiency, accuracy and stability for coordinate transformations, compared to the widely used hyperbolic transformation model.

  3. Learning accurate and interpretable models based on regularized random forests regression

    PubMed Central

    2014-01-01

    Background Many biology related research works combine data from multiple sources in an effort to understand the underlying problems. It is important to find and interpret the most important information from these sources. Thus it will be beneficial to have an effective algorithm that can simultaneously extract decision rules and select critical features for good interpretation while preserving the prediction performance. Methods In this study, we focus on regression problems for biological data where target outcomes are continuous. In general, models constructed from linear regression approaches are relatively easy to interpret. However, many practical biological applications are nonlinear in essence where we can hardly find a direct linear relationship between input and output. Nonlinear regression techniques can reveal nonlinear relationship of data, but are generally hard for human to interpret. We propose a rule based regression algorithm that uses 1-norm regularized random forests. The proposed approach simultaneously extracts a small number of rules from generated random forests and eliminates unimportant features. Results We tested the approach on some biological data sets. The proposed approach is able to construct a significantly smaller set of regression rules using a subset of attributes while achieving prediction performance comparable to that of random forests regression. Conclusion It demonstrates high potential in aiding prediction and interpretation of nonlinear relationships of the subject being studied. PMID:25350120

  4. Teva Pharmaceuticals v. Sandoz: availability of generic glatiramer acetate and the impact to patent litigation claim construction.

    PubMed

    Fogel, Louis E; Ray, Chad J

    2015-01-01

    In the upcoming case of Teva Pharmaceuticals v. Sandoz, the U.S. Supreme Court will address how much deference the appellate court should afford to a trial court's claim construction ruling. The effect of this decision will be far-reaching, as how claims are construed can determine whether a patent is infringed or not infringed, valid or invalid.

  5. The Canadian Legal System, the Robert Latimer Case, and the Rhetorical Construction of (Dis)ability: "Bodies that Matter?"

    ERIC Educational Resources Information Center

    Hayward, Sally

    2009-01-01

    This paper considers Judge Ted Noble's 1997 ruling of the Latimer case in terms of how it rhetorically constructs and privileges the normal, able-bodied status quo, while, at the same time, deconstructs and positions as inferior the "abnormal," dis-abled minority. In this case, Noble not only took the unprecedented step of granting…

  6. [Introduction and advantage analysis of the stepwise method for the construction of vascular trees].

    PubMed

    Zhang, Yan; Xie, Haiwei; Zhu, Kai

    2010-08-01

    A new method for constructing the model of vascular trees was proposed in this paper. By use of this method, the arterial trees in good agreement with the actual structure could be grown. In this process, all vessels in the vascular tree were divided into two groups: the conveying vessels, and the delivering branches. And different branches could be built by different ways. Firstly, the distributing rules of conveying vessels were ascertained by use of measurement data, and then the conveying vessels were constructed in accordance to the statistical rule and optimization criterion. Lastly, delivering branches were modeled by constrained constructive optimization (CCO) on the conveying vessel-trees which had already been generated. In order to compare the CCO method and stepwise method proposed here, two 3D arterial trees of human tongue were grown with their vascular tree having a special structure. Based on the corrosion casts of real arterial tree of human tongue, the data about the two trees constructed by different methods were compared and analyzed, including the averaged segment diameters at respective levels, the distribution and the diameters of the branches of first level at respective directions. The results show that the vascular tree built by stepwise method is more similar to the true arterial of human tongue when compared against the tree built by CCO method.

  7. 12 CFR 226.2 - Definitions and rules of construction.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... attached to real property. The term includes an individual condominium unit, cooperative unit, mobile home...) Residential mortgage transaction means a transaction in which a mortgage, deed of trust, purchase money...

  8. 12 CFR 226.2 - Definitions and rules of construction.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... attached to real property. The term includes an individual condominium unit, cooperative unit, mobile home...) Residential mortgage transaction means a transaction in which a mortgage, deed of trust, purchase money...

  9. 12 CFR 226.2 - Definitions and rules of construction.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... attached to real property. The term includes an individual condominium unit, cooperative unit, mobile home...) Residential mortgage transaction means a transaction in which a mortgage, deed of trust, purchase money...

  10. 40 CFR 60.3000 - When must I comply?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Waste Incineration Units That Commenced Construction On or Before December 9, 2004 Model Rule-Compliance..., postmarked within 10 business days after the final compliance date in table 1 of this subpart. ...

  11. 18 CFR 12.2 - Rules of construction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., DEPARTMENT OF ENERGY REGULATIONS UNDER THE FEDERAL POWER ACT SAFETY OF WATER POWER PROJECTS AND PROJECT WORKS... Licensing determines that compliance with the relevant provision of the license will better protect life...

  12. Applications of Machine Learning and Rule Induction,

    DTIC Science & Technology

    1995-02-15

    An important area of application for machine learning is in automating the acquisition of knowledge bases required for expert systems. In this paper...we review the major paradigms for machine learning , including neural networks, instance-based methods, genetic learning, rule induction, and analytic

  13. Reducing major rule violations in commuter rail operations : the role of distraction and attentional errors

    DOT National Transportation Integrated Search

    2012-10-22

    Recent accidents in commuter rail operations and analyses of rule violations have highlighted the need for : better understanding of the contributory role of distraction and attentional errors. Distracted driving has : thoroughly been studied in rece...

  14. Deficits in Category Learning in Older Adults: Rule-Based Versus Clustering Accounts

    PubMed Central

    2017-01-01

    Memory research has long been one of the key areas of investigation for cognitive aging researchers but only in the last decade or so has categorization been used to understand age differences in cognition. Categorization tasks focus more heavily on the grouping and organization of items in memory, and often on the process of learning relationships through trial and error. Categorization studies allow researchers to more accurately characterize age differences in cognition: whether older adults show declines in the way in which they represent categories with simple rules or declines in representing categories by similarity to past examples. In the current study, young and older adults participated in a set of classic category learning problems, which allowed us to distinguish between three hypotheses: (a) rule-complexity: categories were represented exclusively with rules and older adults had differential difficulty when more complex rules were required, (b) rule-specific: categories could be represented either by rules or by similarity, and there were age deficits in using rules, and (c) clustering: similarity was mainly used and older adults constructed a less-detailed representation by lumping more items into fewer clusters. The ordinal levels of performance across different conditions argued against rule-complexity, as older adults showed greater deficits on less complex categories. The data also provided evidence against rule-specificity, as single-dimensional rules could not explain age declines. Instead, computational modeling of the data indicated that older adults utilized fewer conceptual clusters of items in memory than did young adults. PMID:28816474

  15. System Diagnostic Builder - A rule generation tool for expert systems that do intelligent data evaluation. [applied to Shuttle Mission Simulator

    NASA Technical Reports Server (NTRS)

    Nieten, Joseph; Burke, Roger

    1993-01-01

    Consideration is given to the System Diagnostic Builder (SDB), an automated knowledge acquisition tool using state-of-the-art AI technologies. The SDB employs an inductive machine learning technique to generate rules from data sets that are classified by a subject matter expert. Thus, data are captured from the subject system, classified, and used to drive the rule generation process. These rule bases are used to represent the observable behavior of the subject system, and to represent knowledge about this system. The knowledge bases captured from the Shuttle Mission Simulator can be used as black box simulations by the Intelligent Computer Aided Training devices. The SDB can also be used to construct knowledge bases for the process control industry, such as chemical production or oil and gas production.

  16. Developing country finance in a post-2020 global climate agreement

    NASA Astrophysics Data System (ADS)

    Hannam, Phillip M.; Liao, Zhenliang; Davis, Steven J.; Oppenheimer, Michael

    2015-11-01

    A central task for negotiators of the post-2020 global climate agreement is to construct a finance regime that supports low-carbon development in developing economies. As power sector investments between developing countries grow, the climate finance regime should incentivize the decarbonization of these major sources of finance by integrating them as a complement to the commitments of developed nations. The emergence of the Asian Infrastructure Investment Bank, South-South Cooperation Fund and other nascent institutions reveal the fissures that exist in rules and norms surrounding international finance in the power sector. Structuring the climate agreement in Paris to credit qualified finance from the developing world could have several advantages, including: (1) encouraging low-carbon cooperation between developing countries; (2) incentivizing emerging investors to prefer low-carbon investments; and (3) enabling more cost-effective attainment of national and global climate objectives. Failure to coordinate on standards now could hinder low-carbon development in the decades to come.

  17. The history of efforts to regulate dietary supplements in the USA.

    PubMed

    Swann, John P

    2016-01-01

    This review examines the emergence of dietary supplements and how the Food and Drug Administration (FDA) attempted to regulate these, beginning with the arrival of vitamins and how these were managed under the 1906 Food and Drugs Act, and ending with the seismic influence of the 1994 Dietary Supplement Health and Education Act (DSHEA). Included are the impact of major laws, key court decisions, and the construction of the FDA's supplement actions and rules from the 1920s to the 1990s for products that were neither drugs nor typical foods. Stiff resistance to the regulations by supplement manufacturers, trade associations, politicians, and especially the public at large is an important part of this story. The paper closes with the passage of DSHEA and how it literally changed the definition and parameters of control of dietary supplements. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  18. Rule-based simulation models

    NASA Technical Reports Server (NTRS)

    Nieten, Joseph L.; Seraphine, Kathleen M.

    1991-01-01

    Procedural modeling systems, rule based modeling systems, and a method for converting a procedural model to a rule based model are described. Simulation models are used to represent real time engineering systems. A real time system can be represented by a set of equations or functions connected so that they perform in the same manner as the actual system. Most modeling system languages are based on FORTRAN or some other procedural language. Therefore, they must be enhanced with a reaction capability. Rule based systems are reactive by definition. Once the engineering system has been decomposed into a set of calculations using only basic algebraic unary operations, a knowledge network of calculations and functions can be constructed. The knowledge network required by a rule based system can be generated by a knowledge acquisition tool or a source level compiler. The compiler would take an existing model source file, a syntax template, and a symbol table and generate the knowledge network. Thus, existing procedural models can be translated and executed by a rule based system. Neural models can be provide the high capacity data manipulation required by the most complex real time models.

  19. Evolving fuzzy rules for relaxed-criteria negotiation.

    PubMed

    Sim, Kwang Mong

    2008-12-01

    In the literature on automated negotiation, very few negotiation agents are designed with the flexibility to slightly relax their negotiation criteria to reach a consensus more rapidly and with more certainty. Furthermore, these relaxed-criteria negotiation agents were not equipped with the ability to enhance their performance by learning and evolving their relaxed-criteria negotiation rules. The impetus of this work is designing market-driven negotiation agents (MDAs) that not only have the flexibility of relaxing bargaining criteria using fuzzy rules, but can also evolve their structures by learning new relaxed-criteria fuzzy rules to improve their negotiation outcomes as they participate in negotiations in more e-markets. To this end, an evolutionary algorithm for adapting and evolving relaxed-criteria fuzzy rules was developed. Implementing the idea in a testbed, two kinds of experiments for evaluating and comparing EvEMDAs (MDAs with relaxed-criteria rules that are evolved using the evolutionary algorithm) and EMDAs (MDAs with relaxed-criteria rules that are manually constructed) were carried out through stochastic simulations. Empirical results show that: 1) EvEMDAs generally outperformed EMDAs in different types of e-markets and 2) the negotiation outcomes of EvEMDAs generally improved as they negotiated in more e-markets.

  20. 12 CFR 226.2 - Definitions and rules of construction.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... an individual condominium unit, cooperative unit, mobile home, and trailer, if it is used as a... means a transaction in which a mortgage, deed of trust, purchase money security interest arising under...

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