Science.gov

Sample records for construction programs c-1

  1. Motion-preserving reduction and fixation of C1 Jefferson fracture using a C1 lateral mass screw construct.

    PubMed

    Jo, Kwang-Wook; Park, Ik-Seong; Hong, Jae Taek

    2011-05-01

    The treatment of C1 Jefferson fractures is controversial. Non-surgical treatment with halo fixation always bears the risk of insufficient healing with further instability and increasing neck pain. However, a C1-2 fusion can markedly decrease the rotatory motion of the neck. The aim of this report is to describe a new treatment for C1 Jefferson fractures. We used open reduction and C1 fixation using a bilateral C1 lateral mass screw construct. The screws were connected with a rod and nuts to reduce lateral spread of the lateral masses. This method is an alternative surgical option for C1 Jefferson fractures in select patients and can maintain important C1-2 joint motion.

  2. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Constructive ownership of stock. 1.267(c)-1...) INCOME TAX (CONTINUED) INCOME TAXES Items Not Deductible § 1.267(c)-1 Constructive ownership of stock. (a) In general. (1) The determination of stock ownership for purposes of section 267(b) shall be...

  3. Component School Construction Program.

    ERIC Educational Resources Information Center

    New Brunswick Dept. of Economic Growth, Fredericton.

    In 1968, the Province of New Brunswick initiated a three-phase program to provide for elementary school facilities, employing a component systems approach to their construction. This booklet describes briefly the planning and construction of these schools, and provides graphic and photographic records of the construction in progress as well as of…

  4. (+)-Rimocidin Synthetic Studies: Construction of the C(1-27) Aglycone Skeleton

    PubMed Central

    Smith, Amos B.; Foley, Megan A.; Dong, Shuzhi; Orbin, Alia

    2010-01-01

    Assembly of the C(1-27) macrocyclic skeleton of rimocidinolide, the aglycone of (+)-rimocidin (1), has been achieved in convergent fashion. Key features of the synthetic strategy entail application of multicomponent Type 1 Anion Relay Chemistry (ARC), in conjunction with the SN2/SN2' reaction manifolds of vinyl epoxides, both employing 2-susbtituted-1,3-dithianes to construct the C(1-19) carbon backbone. Yamaguchi union of a C(20-27) vinyl borate ester, possessing the all trans triene, with an advanced C(1-19) vinyl iodide followed by macrocyclization via Suzuki-Miyaura cross-coupling completed construction of the C(1-27) rimocidinolide skeleton. PMID:19621880

  5. Computer Programs for Construction

    NASA Technical Reports Server (NTRS)

    1978-01-01

    A NASA computer program aids Hudson Engineering Corporation, Houston, Texas in the design and construction of huge petrochemical processing plants like the one shown, which is located at Ju'aymah, Saud Arabia. The pipes handling the flow of chemicals are subject to a variety of stresses, such as weight and variations in temperature. Hudson Engineering uses a COSMIC piping flexibility analysis computer program to analyze and insure the necessary strength and flexibility of the pipes. This program helps the company realize substantial savings in reduced engineering time.

  6. Constructing Programs from Example Computations.

    ERIC Educational Resources Information Center

    Bierman, A. W.; Krishnaswamy, R.

    This paper describes the construction and implementation of an autoprogramming system. An autoprogrammer is an interactive computer programming system which automatically constructs computer programs from example computations executed by the user. The example calculations are done in a scratch pad fashion at a computer display, and the system…

  7. Construction of the programmed motion

    SciTech Connect

    Man, T.B.

    1982-08-01

    The objective of this paper is to outline some problems of the programmed motion. The Erugin's method for the construction of the set of differential equations according to the prescribed integrals, which plays a crucial role in the development of such motions, is discussed. Possible modifications of the inverse problem of dynamics is pointed out. One of the modifications, such as the construction of the functional, which takes stationary value on the solution of the constructed equations, has been worked out in detail.

  8. Electrodril system field test program. Phase II: Task C-1-deep drilling system demonstration. Final report for Phase II: Task C-1

    SciTech Connect

    Taylor, P D

    1981-04-01

    The Electrodril Deep Drilling System field test demonstrations were aborted in July 1979, due to connector problems. Subsequent post test analyses concluded that the field replacable connectors were the probable cause of the problems encountered. The designs for both the male and female connectors, together with their manufacturing processes, were subsequently modified, as was the acceptance test procedures. A total of nine male and nine female connectors were manufactured and delivered during the 2nd Quarter 1980. Exhaustive testing was then conducted on each connector as a precursor to formal qualification testing conducted during the month of October 1980, at the Brown Oil Tool test facility located in Houston, Texas. With this report, requirements under Phase II, Task C-1 are satisfied. The report documents the results of the connector qualification test program which was successfully completed October 28, 1980. In general, it was concluded that connector qualification had been achieved and plans are now in progress to resume the field test demonstration program so that Electrodril System performance predictions and economic viability can be evaluated.

  9. Language constructs for modular parallel programs

    SciTech Connect

    Foster, I.

    1996-03-01

    We describe programming language constructs that facilitate the application of modular design techniques in parallel programming. These constructs allow us to isolate resource management and processor scheduling decisions from the specification of individual modules, which can themselves encapsulate design decisions concerned with concurrence, communication, process mapping, and data distribution. This approach permits development of libraries of reusable parallel program components and the reuse of these components in different contexts. In particular, alternative mapping strategies can be explored without modifying other aspects of program logic. We describe how these constructs are incorporated in two practical parallel programming languages, PCN and Fortran M. Compilers have been developed for both languages, allowing experimentation in substantial applications.

  10. FELIX construction status and experimental program

    SciTech Connect

    Turner, L.R.; Praeg, W.F.; Knott, M.J.; Lari, R.J.; McGhee, D.G.; Wehrle, R.B.

    1983-01-01

    FELIX (Fusion Electromagnetic Induction Experiment) is an experimental test facility being constructed at Argonne National Laboratory (ANL) for the study of electromagnetic effects in the first wall/blanket/shield (FWBS) systems of fusion reactors. The facility design, construction status, experimental program, instrumentation, and associated computer-code comparisons are described.

  11. Department of Defense Budget for Fiscal Years 1990 and 1991. Construction Programs (C-1)

    DTIC Science & Technology

    1989-01-09

    NEW YORK NAVY RESERVE AFRC FLOYD BENNETT FIELD, BROOKLYN ELECTRICAL FEEDER IMPROVEMENT 800 AFRC FLOYD BENNETT FIELD, BROOKLYN 800 STEWART...ANX NAVAL SUPPLY CTR MUNICIPAL SEWER CONNECTION 3,300 WILLIAMSBURG CHEATHAM ANX NAVAL SUPPLY CTR 3,300 YORKTOWN NAVAL OPHTHALMIC SPT & TRNG ACT... WILLIAMSBURG CHEATHAM ANX NAVAL SUPPLY CTR SURVEY SUPFORT FACILITY 18,500 WILLIAMSBURG CHEATHAM ANN NAVAL SUPPLY CTR 18,500 YORKTOWN NAVAL WEAPONS

  12. Construction Programs (C-1), Department of Defense Budget, Fiscal Years 2004/2005

    DTIC Science & Technology

    2003-02-01

    RICHARDSON BARRACKS COMPLEX - D STREET PH 3 33,000 33,000 33,000...FORT RICHARDSON AK BARRACKS COMPLEX - D STREET PH 3 33,000 33,000 33,000... D E PA RT ME NT OF DEFE N S E U N ITED STATE S OF A M ER IC A Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the

  13. Construction Programs (C-1) Department of Defense Budget for Fiscal Year 1993

    DTIC Science & Technology

    1992-01-29

    DEMILITARIZATIAN FACILITY 11,800f TOOELE ARMY DEPOT 61,200 **ARMY 61,650 AIR FORCE HILL AFB DEPOT WAREHOUSE 16,000 ICBM NON-DESTRUCTIVE INSPECTION BUNKER 2,800...ADD/ALTER STRAT TRNG RANGE TECH OPS FAC 700 CONRAD STRS 700 HAVRE STRS ADD/ALTER STRAT TRNG RANGE TECH OPS FAC 700 HAVRE STRS 700 **AIR FORCE 1,400 ARMY...WHITE SANDS MISSILE RANGE 20,000 ARMY NATIONAL GUARD LAS CRUCES ARMY AVIATION SUPPORT FACIL 1,014 LAS CRUCES 1,014 SANTA FE TRNG SITE, AMMO BUNKER 340

  14. Construction Programs (C-1), Department of Defense Budget for Fiscal Year 1995

    DTIC Science & Technology

    1994-02-01

    FEB 1994 INSIDE THE UNITED STATES ($ THOUSANDS) STATE/COMP./INSTALLATION PROJ COST TOTAL -------------------. PROJECT NAME...THOUS.AMDS) STATE/CONP./INSTALLATION PROJ COST TOTAL -------------------. PROJECT NAME - - -.----------.--------- ALASKA AIR FORCE EIELSON AFB UNDERGROUND FUEL... PROJECT NAME -- ----.----------.-------- ARIZONA AIR NATIONAL GUARD TUCSON IAP JET FUEL STORAGE COMPLEX 7,200 TUCSON IAP 7.200 AIR FORCE RESERVE DAVIS

  15. Construction Programs (C-1). Department of Defense Budget Fiscal Year 2010

    DTIC Science & Technology

    2009-05-01

    ANNISTON ARMY DEPOT INDUSTRIAL WASTE WATER TREATMENT PLANT 26,000 26,000 26,000 26,000...MP/CID MEDICAL UNIT OPERATIONS FACILITIES 24,000 24,000 24,000 24,000 SOLDIER FAMILY ASSISTANCE CENTER (SFAC...SUITLAND NATIONAL MARITIME INTEL CENTER (INC 3) 52,069 52,069 52,069

  16. Comparison of fatigue strength of C2 pedicle screws, C2 pars screws, and a hybrid construct in C1-C2 fixation.

    PubMed

    Su, Brian W; Shimer, Adam L; Chinthakunta, Suresh; Salloum, Kanaan; Ames, Christopher P; Vaccaro, Alexander R; Bucklen, Brandon

    2014-01-01

    A biomechanical study comparing the fatigue strength of different types of C2 fixation in a C1-C2 construct. To determine the pullout strength of a C2 pedicle screw and C2 pars screw after cyclical testing and differentiate differences in stiffness pre- and post-cyclical loading of 3 different C1-C2 fixations. Some surgeons use a short C2 pars screw in a C1-C2 construct, because it is less technically demanding and/or when the vertebral artery is high riding. Difference in construct stiffness between use of bilateral C2 pedicle screws, bilateral C2 pars screws, or a hybrid construct is unknown. Biomechanical testing was performed on 15 specimens. A bicortical C1 lateral mass screw was used in combination with 1 of 3 methods of C2 fixation: (1) bilateral long C2 pedicle screws (LL), (2) bilateral 14-mm C2 pars screws (SS), and (3) unilateral long C2 pedicle screw with a contralateral 14-mm C2 pars screw (LS). Each construct was subject to 16,000 cycles to simulate the immediate postoperative period. Changes in motion in flexion-extension, lateral bending, and axial rotation were calculated. This was followed by pullout testing. The ability to limit range of motion significantly decreased after cyclical testing in flexion-extension, lateral bending, and axial rotation for all 3 groups. After loading, the LL and LS groups had less percentage of increase in motion in flexion-extension and lateral bending than the SS group. Overall, the average pullout strength of a pedicle screw was 92% stronger than a pars screw. C2 pedicle screws have twice the pullout strength of C2 pars screws after cyclical loading. In cases in which the anatomy limits placement of bilateral C2 pedicle screws, a construct using a unilateral C2 pedicle screw with a contralateral short pars screw is a viable option and compares favorably with a bilateral C2 pedicle screw construct. N/A.

  17. 40 CFR 265.19 - Construction quality assurance program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Construction quality assurance program..., STORAGE, AND DISPOSAL FACILITIES General Facility Standards § 265.19 Construction quality assurance program. (a) CQA program. (1) A construction quality assurance (CQA) program is required for all surface...

  18. 40 CFR 264.19 - Construction quality assurance program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Construction quality assurance program... FACILITIES General Facility Standards § 264.19 Construction quality assurance program. (a) CQA program. (1) A construction quality assurance (CQA) program is required for all surface impoundment, waste pile, and landfill...

  19. 40 CFR 265.19 - Construction quality assurance program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Construction quality assurance program..., STORAGE, AND DISPOSAL FACILITIES General Facility Standards § 265.19 Construction quality assurance program. (a) CQA program. (1) A construction quality assurance (CQA) program is required for all surface...

  20. 40 CFR 264.19 - Construction quality assurance program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Construction quality assurance program... FACILITIES General Facility Standards § 264.19 Construction quality assurance program. (a) CQA program. (1) A construction quality assurance (CQA) program is required for all surface impoundment, waste pile, and landfill...

  1. 40 CFR 264.19 - Construction quality assurance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Construction quality assurance program... FACILITIES General Facility Standards § 264.19 Construction quality assurance program. (a) CQA program. (1) A construction quality assurance (CQA) program is required for all surface impoundment, waste pile, and...

  2. 40 CFR 265.19 - Construction quality assurance program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Construction quality assurance program..., STORAGE, AND DISPOSAL FACILITIES General Facility Standards § 265.19 Construction quality assurance program. (a) CQA program. (1) A construction quality assurance (CQA) program is required for all...

  3. Flexible Language Constructs for Large Parallel Programs

    DOE PAGES

    Rosing, Matt; Schnabel, Robert

    1994-01-01

    The goal of the research described in this article is to develop flexible language constructs for writing large data parallel numerical programs for distributed memory (multiple instruction multiple data [MIMD]) multiprocessors. Previously, several models have been developed to support synchronization and communication. Models for global synchronization include single instruction multiple data (SIMD), single program multiple data (SPMD), and sequential programs annotated with data distribution statements. The two primary models for communication include implicit communication based on shared memory and explicit communication based on messages. None of these models by themselves seem sufficient to permit the natural and efficient expression ofmore » the variety of algorithms that occur in large scientific computations. In this article, we give an overview of a new language that combines many of these programming models in a clean manner. This is done in a modular fashion such that different models can be combined to support large programs. Within a module, the selection of a model depends on the algorithm and its efficiency requirements. In this article, we give an overview of the language and discuss some of the critical implementation details.« less

  4. Flexible language constructs for large parallel programs

    NASA Technical Reports Server (NTRS)

    Rosing, Matthew; Schnabel, Robert

    1993-01-01

    The goal of the research described is to develop flexible language constructs for writing large data parallel numerical programs for distributed memory (MIMD) multiprocessors. Previously, several models have been developed to support synchronization and communication. Models for global synchronization include SIMD (Single Instruction Multiple Data), SPMD (Single Program Multiple Data), and sequential programs annotated with data distribution statements. The two primary models for communication include implicit communication based on shared memory and explicit communication based on messages. None of these models by themselves seem sufficient to permit the natural and efficient expression of the variety of algorithms that occur in large scientific computations. An overview of a new language that combines many of these programming models in a clean manner is given. This is done in a modular fashion such that different models can be combined to support large programs. Within a module, the selection of a model depends on the algorithm and its efficiency requirements. An overview of the language and discussion of some of the critical implementation details is given.

  5. Epigenetic Regulation of Placental NR3C1: Mechanism Underlying Prenatal Programming of Infant Neurobehavior by Maternal Smoking?

    PubMed Central

    Stroud, Laura R.; Papandonatos, George D.; Salisbury, Amy L.; Phipps, Maureen G.; Huestis, Marilyn A.; Niaura, Raymond; Padbury, James F.; Marsit, Carmen; Lester, Barry

    2015-01-01

    Epigenetic regulation of the placental glucocorticoid receptor gene (NR3C1) was investigated as a mechanism underlying links between maternal smoking during pregnancy (MSDP) and infant neurobehavior in 45 mother-infant pairs (49% MSDP-exposed; 52% minorities; ages 18-35). The NICU Network Neurobehavioral Scale was administered 7 times over the first postnatal month; methylation of placental NR3C1 was assessed via bisulfite pyrosequencing. Increased placental NR3C1 methylation was associated with increased infant attention and self-regulation, and decreased lethargy and need for examiner soothing over the first postnatal month. A causal steps approach revealed that NR3C1 methylation and MSDP were independently associated with lethargic behavior. Although preliminary, results highlight the importance of epigenetic mechanisms in elucidating pathways to neurobehavioral alterations from MSDP. PMID:26822442

  6. 78 FR 4157 - Manufactured Home Construction and Safety Standards Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Manufactured Home Construction and Safety Standards Program AGENCY: Office of the... information: Title of Proposal: Manufactured Home Construction and Safety Standards Program. OMB Control...

  7. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works-Clean Water Act § 35.903 Summary of construction grant program. (a) The construction of federally financed waste... States to provide for, encourage and assist public participation in the Construction Grants Program....

  8. Epigenetic Regulation of Placental "NR3C1": Mechanism Underlying Prenatal Programming of Infant Neurobehavior by Maternal Smoking?

    ERIC Educational Resources Information Center

    Stroud, Laura R.; Papandonatos, George D.; Salisbury, Amy L.; Phipps, Maureen G.; Huestis, Marilyn A.; Niaura, Raymond; Padbury, James F.; Marsit, Carmen J.; Lester, Barry M.

    2016-01-01

    Epigenetic regulation of the placental glucocorticoid receptor gene ("NR3C1") was investigated as a mechanism underlying links between maternal smoking during pregnancy (MSDP) and infant neurobehavior in 45 mother-infant pairs (49% MSDP-exposed; 52% minorities; ages 18-35). The Neonatal Intensive Care Unit (NICU) Network Neurobehavioral…

  9. Epigenetic Regulation of Placental "NR3C1": Mechanism Underlying Prenatal Programming of Infant Neurobehavior by Maternal Smoking?

    ERIC Educational Resources Information Center

    Stroud, Laura R.; Papandonatos, George D.; Salisbury, Amy L.; Phipps, Maureen G.; Huestis, Marilyn A.; Niaura, Raymond; Padbury, James F.; Marsit, Carmen J.; Lester, Barry M.

    2016-01-01

    Epigenetic regulation of the placental glucocorticoid receptor gene ("NR3C1") was investigated as a mechanism underlying links between maternal smoking during pregnancy (MSDP) and infant neurobehavior in 45 mother-infant pairs (49% MSDP-exposed; 52% minorities; ages 18-35). The Neonatal Intensive Care Unit (NICU) Network Neurobehavioral…

  10. Alberta's Funding Program for School Construction.

    ERIC Educational Resources Information Center

    Kulba, John W.; Hathaway, Warren E.

    1983-01-01

    A capital funding plan was introduced in Alberta in 1979 to more effectively control school construction and ensure that provincial priorities were being achieved. The formula includes factors to adjust for financial equity, district utilization of space, approved areas, and changes in construction costs. (MLF)

  11. Construction safety program for the National Ignition Facility

    SciTech Connect

    Cerruti, S.J.

    1997-06-26

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and initial activation and operation of NIF at LLNL during the construction period of NIF.

  12. Local School Construction Programs. Bulletin, 1957, No. 20

    ERIC Educational Resources Information Center

    Viles, N. E.

    1957-01-01

    This bulletin is designed as an outline to direct the attention of local officials to various features and steps meriting attention in planning and carrying out a school-plant construction program. Planning, administration, and construction practices and procedures may vary with buildings of different sizes or types of construction or with those…

  13. Construction safety program for the National Ignition Facility

    SciTech Connect

    Cerruti, S.J.

    1997-01-01

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and initial activation and operation of NIF at LLNL during the construction period of NIF. During this period, all workers are required to implement measures to create a universal awareness which promotes safe practice at the work site, and which will achieve NIF`s management objectives in preventing accidents and illnesses. Construction safety for NIF is predicated on everyone performing their jobs in a manner which prevents job-related disabling injuries and illnesses. The CSP outlines the minimum environment, safety, and health (ES&H) standards, LLNL policies and the Construction Industry Institute (CII) Zero Injury Techniques requirements that all workers at the NIF construction site shall adhere to during the construction period of NIF. It identifies the safety requirements which the NIF organizational Elements, construction contractors and construction subcontractors must include in their safety plans for the construction period of NIF, and presents safety protocols and guidelines which workers shall follow to assure a safe and healthful work environment. The CSP also identifies the ES&H responsibilities of LLNL employees, non-LLNL employees, construction contractors, construction subcontractors, and various levels of management within the NIF Program at LLNL. In addition, the CSP contains the responsibilities and functions of ES&H support organizations and administrative groups, and describes their interactions with the NIF Program.

  14. Youth Apprenticeship in Construction Trades. Student Handbook. Program Requirements.

    ERIC Educational Resources Information Center

    Manatee County Schools, Bradenton, FL.

    This student handbook contains information about participating in the construction trades program in the Manatee County (Florida) Public Schools. The first part of the handbook consists of general information about the program: program goals and objectives, intended outcomes, benefits to students, student responsibilities, contractor…

  15. Construction Pre-Apprenticeship Programs: Results from a National Survey

    ERIC Educational Resources Information Center

    Conway, Maureen; Gerber, Allison

    2009-01-01

    This publication shares findings from a WSI-conducted survey of pre-apprenticeship programs in the construction trades. Based on responses from 260 programs nationwide, the report presents information about program size, services offered, populations served, funding sources, and successes and challenges in placing trainees in apprenticeships or…

  16. School Construction Programming in Florida, K-12.

    ERIC Educational Resources Information Center

    Chick, Charles E.; And Others

    To identify the need for construction and to estimate the cost of meeting existing and future capital outlay needs of Florida's 67 school districts, this paper attempts to provide a broad overview of the Florida system. More specifically, the paper describes how the State system of public schools is organized, the history of capital outlay survey…

  17. Construction of C1-symmetric zirconium complexes by the design of new Salan ligands. Coordination chemistry and preliminary polymerisation catalysis studies.

    PubMed

    Cohen, Ad; Yeori, Adi; Kopilov, Jacob; Goldberg, Israel; Kol, Moshe

    2008-05-14

    The first synthesis of achiral and chiral [ONNO']-type Salan ligands featuring two different phenol arms, and the diastereoselective formation of the corresponding octahedral C1-symmetric zirconium complexes is described; the activity and isospecificity induction of the [ONNO']Zr(bn)2 complexes in 1-hexene polymerisation reflected those of the parent symmetric compounds.

  18. Construction Productivity Advancement Research (CPAR) Program.

    DTIC Science & Technology

    1998-04-01

    Inc., Trenchless Technology Center, Delft Gee-technics Institute, and the City of Vicksburg. These companies and their staffs are commended for...CPAR) program: the American Gas Association’s (AGA) P. R. C. International, the Trenchless Technology Center of Louisiana Tech University, and Delft...development of trenchless techniques involving HDD. A direct result of this research was a large-scale field test program during installation of pipelines

  19. Constructing Effective Corporate Adventure Training Programs.

    ERIC Educational Resources Information Center

    Gass, Michael; And Others

    1992-01-01

    Effective corporate adventure training programs: (1) develop parallel structures between the adventure experience and the workplace (context); (2) consider how the learning will address a company's future needs (continuity); (3) provide learners with valid information and feedback on their actions (consequences); and (4) create physically and…

  20. Public School Construction Program. Administrative Procedures Guide. Revised.

    ERIC Educational Resources Information Center

    Maryland State Interagency Committee on School Construction, Baltimore.

    The State of Maryland has published this guide that provides State and local personnel, architects, and governmental officials with the method of operation and administration of the State's Public School Construction Program. The material is arranged in sequential order and follows a project from inception through design, construction, and…

  1. 40 CFR 35.903 - Summary of construction grant program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Summary of construction grant program. 35.903 Section 35.903 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER... developed urban areas should be included as part of the development costs of the new construction in...

  2. 25 CFR 1000.254 - May a Tribe/Consortium reallocate funds from a construction program to a non-construction program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false May a Tribe/Consortium reallocate funds from a... Tribe/Consortium reallocate funds from a construction program to a non-construction program? No, a Tribe/Consortium may not reallocate funds from a construction program to a non-construction program...

  3. 25 CFR 1000.254 - May a Tribe/Consortium reallocate funds from a construction program to a non-construction program?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false May a Tribe/Consortium reallocate funds from a... Tribe/Consortium reallocate funds from a construction program to a non-construction program? No, a Tribe/Consortium may not reallocate funds from a construction program to a non-construction program...

  4. 25 CFR 1000.254 - May a Tribe/Consortium reallocate funds from a construction program to a non-construction program?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false May a Tribe/Consortium reallocate funds from a... Tribe/Consortium reallocate funds from a construction program to a non-construction program? No, a Tribe/Consortium may not reallocate funds from a construction program to a non-construction program...

  5. 25 CFR 1000.254 - May a Tribe/Consortium reallocate funds from a construction program to a non-construction program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false May a Tribe/Consortium reallocate funds from a... Tribe/Consortium reallocate funds from a construction program to a non-construction program? No, a Tribe/Consortium may not reallocate funds from a construction program to a non-construction program...

  6. Annual Program. Library Services and Construction. FY 1976 (Carryover Funds.)

    ERIC Educational Resources Information Center

    North Carolina State Library, Raleigh.

    A consolidated listing of projects for Titles I and III opens this progress report on Library Services and Construction Act (LSCA) programs in North Carolina for fiscal year l976. Suggested allocations of carryover funds for administration, State Library programs, institutions and reference services, state audiovisual services, grants, audiovisual…

  7. Guidelines for Implementing State Skill Standards Certificate Program in Construction.

    ERIC Educational Resources Information Center

    Wisconsin State Dept. of Workforce Development, Madison.

    This packet contains guidelines, a student competency checklist, and student evaluation sheet for use in a Wisconsin school-to-work state skill standards certificate program in construction. The guidelines provide a planning resource for implementing the program, which was created in partnership with unions, employers, the state Department of…

  8. Guidelines for Implementing State Skill Standards Certificate Program in Construction.

    ERIC Educational Resources Information Center

    Wisconsin State Dept. of Workforce Development, Madison.

    This packet contains guidelines, a student competency checklist, and student evaluation sheet for use in a Wisconsin school-to-work state skill standards certificate program in construction. The guidelines provide a planning resource for implementing the program, which was created in partnership with unions, employers, the state Department of…

  9. Effects of a Combined Aerobic and Resistance Exercise Program on C1q/TNF-Related Protein-3 (CTRP-3) and CTRP-5 Levels

    PubMed Central

    Choi, Hae Yoon; Park, Ji Woo; Lee, Namseok; Hwang, Soon Young; Cho, Geum Ju; Hong, Ho Cheol; Yoo, Hye Jin; Hwang, Taek Geun; Kim, Seon Mi; Baik, Sei Hyun; Park, Kyong Soo; Youn, Byung-Soo; Choi, Kyung Mook

    2013-01-01

    OBJECTIVE To examine the effect of a combined exercise program on C1q/tumor necrosis factor-related protein (CTRP) 3 and CTRP-5 levels and novel adiponectin paralogs suggested to be links between metabolism and inflammation and to evaluate sex differences and association with cardiometabolic risk factors in humans with use of a newly developed ELISA. RESEARCH DESIGN AND METHODS This cross-sectional study explored the implications of CTRP-3 and CTRP-5 on cardiometabolic parameters in 453 nondiabetic Korean adults. In addition, we evaluated the impact of a 3-month combined exercise program on CTRP-3 and CTRP-5 levels in 76 obese women. The exercise program consisted of 45 min of aerobic exercise at an intensity of 60–75% of the age-predicted maximum heart rate (300 kcal/session) and 20 min of resistance training (100 kcal/session) five times per week. RESULTS Both CTRP-3 and CTRP-5 concentrations were significantly higher in women (P < 0.001) than in men (P = 0.030). In a multiple stepwise regression analysis, CTRP-3 levels were independently associated with age, sex, and triglyceride, LDL cholesterol, adiponectin, and retinol-binding protein 4 (RBP4) levels (R2 = 0.182). After 3 months of a combined exercise program, cardiometabolic risk factors, including components of metabolic syndrome, insulin resistance, and RBP4 levels, decreased significantly. In particular, CTRP-3 levels decreased significantly (median [interquartile range] 444.3 [373.8–535.0] to 374.4 [297.2–435.9], P < 0.001), whereas CTRP-5 levels were slightly increased (34.1 [28.6–44.3] to 38.4 [29.8–55.1], P = 0.048). CONCLUSIONS A 3-month combined exercise program significantly decreased CTRP-3 levels and modestly increased CTRP-5 levels in obese Korean women. PMID:23780948

  10. The NIOSH Construction Program: research to practice, impact, and developing a National Construction Agenda.

    PubMed

    Gillen, Matt

    2010-06-01

    The U.S. National Institute for Occupational Safety and Health (NIOSH) conducts research to improve and protect the health and safety of workers. This paper describes the experience of the NIOSH Construction Program with two recent program planning initiatives intended to improve the program: (a) an independent external review of work over the past decade and (b) the development of strategic goals organized into a "National Construction Agenda" to guide a decade of future work. These goals, developed with input from construction industry stakeholders and researchers, are a part of the NIOSH National Occupational Research Agenda (NORA) initiative. The NORA goals are intended to provide an ambitious set of goals for all construction stakeholders to work together on. Both efforts relate to insuring the relevance and impact of research, reflecting an emerging policy perspective that research programs should be judged not just by the quality and quantity of science produced, but by the industry impact and tangible benefit resulting from the research. This paper describes how views on research planning have evolved to incorporate lessons learned about how research leads to improved safety and health for workers. It also describes the process used to develop the goals and the resulting strategic and intermediate goals that comprise the National Construction Agenda. (c) 2010 Elsevier Ltd. All rights reserved.

  11. Development of a safety communication and recognition program for construction.

    PubMed

    Sparer, Emily H; Herrick, Robert F; Dennerlein, Jack T

    2015-05-01

    Leading-indicator-based (e.g., hazard recognition) incentive programs provide an alternative to controversial lagging-indicator-based (e.g., injury rates) programs. We designed a leading-indicator-based safety communication and recognition program that incentivized safe working conditions. The program was piloted for two months on a commercial construction worksite and then redesigned using qualitative interview and focus group data from management and workers. We then ran the redesigned program for six months on the same worksite. Foremen received detailed weekly feedback from safety inspections, and posters displayed worksite and subcontractor safety scores. In the final program design, the whole site, not individual subcontractors, was the unit of analysis and recognition. This received high levels of acceptance from workers, who noted increased levels of site unity and team-building. This pilot program showed that construction workers value solidarity with others on site, demonstrating the importance of health and safety programs that engage all workers through a reliable and consistent communication infrastructure. © The Author(s) 2015 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  12. Citizens Utilities Company's successful residential new construction market transformation program

    SciTech Connect

    Caulfield, T.O.; Shepherd, M.A.

    1998-07-01

    Citizens Utilities Company, Arizona Electric Division (CUC/AED) fielded a Residential New Construction Program (RNC) in the forth quarter of 1994 that had been designed from conception as a market transformation program. The CUC RNC Program encouraged builders to adopt energy efficient building practices for new homes by supplying builders estimates of energy savings, supplying inspections services to assist builders in applying energy efficient building practices while verifying compliance, and posting and promoting the home as energy efficient during the sales period. Measures generally required to qualify for the program were R-38 ceiling insulation, R-21 wall insulation, polysealing of all infiltration gaps during construction, well sealed air-conditioning ducts, and an air conditioner Seasonal Energy Efficiency Rating (SEER) of 11.0 or greater. In less than two years the program achieved over 17% market penetration without offering rebates to builders. This paper reviews the design of the program, including a discussion of the features felt to be primarily responsible for its success. It reviews the levels of penetration achieved, free-ridership, spillover, and market barriers encountered. Finally it proposes improvements to the program designed to carry it the next step toward a self-sustaining market transformation program.

  13. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, workers measure the piling being pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  14. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, pilings are being pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  15. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, the crane crawler lifts a piling into place to be pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  16. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, the crane crawler puts a piling into place to be pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  17. Constructing lightning towers for the Constellation Program and

    NASA Image and Video Library

    2007-11-09

    On Launch Pad 39B at NASA's Kennedy Space Center, the crane crawler lifts a piling off a truck. The piling will be pounded into the ground to help construct lightning towers for the Constellation Program and Ares/Orion launches. Pad B will be the site of the first Ares vehicle launch, including Ares I-X which is scheduled for April 2009.

  18. Language constructs and runtime systems for compositional parallel programming

    SciTech Connect

    Foster, I.; Kesselman, C.

    1995-03-01

    In task-parallel programs, diverse activities can take place concurrently, and communication and synchronization patterns are complex and not easily predictable. Previous work has identified compositionality as an important design principle for task-parallel programs. In this paper, we discuss alternative approaches to the realization of this principle. We first provide a review and critical analysis of Strand, an early compositional programming language. We examine the strengths of the Strand approach and also its weaknesses, which we attribute primarily to the use of a specialized language. Then, we present an alternative programming language framework that overcomes these weaknesses. This framework uses simple extensions to existing sequential languages (C++ and Fortran) and a common runtime system to provide a basis for the construction of large, task-parallel programs. We also discuss the runtime system techniques required to support these languages on parallel and distributed computer systems.

  19. 42 CFR 137.275 - May Self-Governance Tribes include IHS construction programs in a construction project agreement...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false May Self-Governance Tribes include IHS construction... OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Purpose and Scope § 137.275 May Self... agreement? Yes, Self-Governance Tribes may choose to assume construction programs in a construction...

  20. The Gene Construction Kit: a new computer program for manipulating and presenting DNA constructs.

    PubMed

    Gross, R H

    1990-06-01

    The Gene Construction Kit is a new tool for manipulating and displaying DNA sequence information. Constructs can be displayed either graphically or as formatted sequence. Segments of DNA can be cut out with restriction enzymes and pasted into other sites. The program keeps track of staggered ends and notifies the user of incompatibilities and offers a choice of ligation options. Each segment of a construct can have its own defined thickness, pattern, direction and color. The sequence listing can be displayed in any font and style in user defined grouping. Nucleotide positions can be displayed as can restriction sites and protein sequences. The DNA can be displayed as either single- or double-stranded. Restriction sites can be readily marked. Alternative views of the DNA can be maintained and the history of the construct automatically stored. Gel electrophoresis patterns can be generated and can be used in cloning project design. Extensive comments can be stored with the construct and can be searched rapidly for key words. High quality illustrations showing multiple editable constructs with added graphics and text information can be generated for slides, posters or publication.

  1. Construction: a model program for infection control compliance.

    PubMed

    Kidd, Francine; Buttner, Clark; Kressel, Amy B

    2007-06-01

    In the 21st century, one of the most challenging tasks for the infection control practitioner (ICP) is establishing collegiality and trust with contractors, architects, maintenance and engineering personnel. We describe how an urban teaching hospital's infection control program cooperated with contractors during a large demolition, construction, and renovation project in order to protect its large population of immunosuppressed patients. Most contractors are not accustomed to taking special precautions during demolition. Because of a previous Aspergillus outbreak in our heart transplant population, we already had an established infection control (IC) training program for contractors. We expanded and codified it in response to a major hospital renovation. The IC, in-house Design and Construction, and outside contractors meet before the initiation of all major renovation projects to anticipate IC concerns and proactively plan for infection control interventions. Now, all contractors and maintenance staff are required to receive IC training at the time of their employment. A hospital identification badge with attached sticker that indicates the IC training date is required. Infection Control Risk Assessments (ICRA) are initiated by project managers and completed jointly with IC. The ICPs make rounds on all projects at least weekly and large projects are visited daily. We established a team comprised of ICP, project manager, construction manager, and area nurse manager to monitor and make recommendations for improvement continually during the project. Staff are educated about construction so they can help monitor airflow and cleanliness. Our contractors are more compliant with our IC specifications since they now understand why we insist on them. Through the years of major construction, the workers have jumped on the bandwagon. It is not unusual for construction or maintenance staff to contact IC for advice. There were four years of extensive construction without any

  2. OSHA lead in construction compliance directive: Medical surveillance program

    SciTech Connect

    Vernon, L.S.

    1994-11-01

    This article is part of a series that reviews the Occupational Health and Safety Administration (OSHA) Instruction CPL 2-2.58, a compliance directive for 29 CFR 1926.62, Lead Exposure in Construction. The OSHA document is intended to provide guidance to those charged with field enforcement of the lead regulation; however, it also provides vital information to those in industry who must comply with the regulation. This month, the requirements for employer medical surveillance programs are discussed.

  3. Automating construction through the use of robotics and Graphical Programming

    SciTech Connect

    McDonald, M.J.; Palmquist, R.D.

    1993-08-01

    Sandia has developed an advanced operational control system approach, called Graphical Programming, to design and operate robot systems in unstructured environments. This Graphical Programming approach produces robot systems that are faster to develop and use, safer in operation, and cheaper overall than altemative teleoperation or autonomous robot control systems. This approach uses 3-D visualization and simulation software with intuitive operator interfaces for the programming and control of complex robotic systems. Supervisor software modules allow an operator to command and simulate complex tasks in a graphic preview mode and, when acceptable, command the actual robots and monitor their motions with the graphic system. Graphical Programming Supervisors maintain registration with the real world and allow the robot to perform tasks that cannot be accurately represented with models alone by using a combination of model and sensor-based control. All of these capabilities when combined result in a flexible system which is readily able to meet the demands called for in construction automation. This paper describes the Graphical Programming approach, several example control systems that use Graphical Programming, key features necessary for implementing successful Graphical Programming systems, and specific examples of applying these systems to robotic operations.

  4. 25 CFR 1000.254 - May a Tribe/Consortium reallocate funds from a construction program to a non-construction program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... construction program to a non-construction program? 1000.254 Section 1000.254 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.254 May...

  5. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction...

  6. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction...

  7. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction...

  8. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction...

  9. Construction Program Management: An Effective Tool for the Delivery of Educational Facilities on the International Scene.

    ERIC Educational Resources Information Center

    Campbell, Robert W.

    1992-01-01

    All international endeavors of major size and duration have been conducted under the concept of construction program management. Examples in Saudi Arabia, Qatar, Brazil, and Guyana illustrate the constancy and coordination that international construction program management provides. (MLF)

  10. Better Space Construction Decisions by Instructional Program Simulation Utilizing the Generalized Academic Simulation Programs.

    ERIC Educational Resources Information Center

    Apker, Wesley

    This school district utilized the generalized academic simulation programs (GASP) to assist in making decisions regarding the kinds of facilities that should be constructed at Pilchuck Senior High School. Modular scheduling was one of the basic educational parameters used in determining the number and type of facilities needed. The objectives of…

  11. System Analysis in Instructional Programming: The Initial Phases of the Program Construction Process.

    ERIC Educational Resources Information Center

    Bjerstedt, Ake

    A three-volume series describes the construction of a self-instructional system as a work process with three main phases: system analysis, system synthesis, and system modification and evaluation. After an introductory discussion of some basic principles of instructional programing, this first volume focuses on the system analysis phase,…

  12. Genetic programs constructed from layered logic gates in single cells.

    PubMed

    Moon, Tae Seok; Lou, Chunbo; Tamsir, Alvin; Stanton, Brynne C; Voigt, Christopher A

    2012-11-08

    Genetic programs function to integrate environmental sensors, implement signal processing algorithms and control expression dynamics. These programs consist of integrated genetic circuits that individually implement operations ranging from digital logic to dynamic circuits, and they have been used in various cellular engineering applications, including the implementation of process control in metabolic networks and the coordination of spatial differentiation in artificial tissues. A key limitation is that the circuits are based on biochemical interactions occurring in the confined volume of the cell, so the size of programs has been limited to a few circuits. Here we apply part mining and directed evolution to build a set of transcriptional AND gates in Escherichia coli. Each AND gate integrates two promoter inputs and controls one promoter output. This allows the gates to be layered by having the output promoter of an upstream circuit serve as the input promoter for a downstream circuit. Each gate consists of a transcription factor that requires a second chaperone protein to activate the output promoter. Multiple activator-chaperone pairs are identified from type III secretion pathways in different strains of bacteria. Directed evolution is applied to increase the dynamic range and orthogonality of the circuits. These gates are connected in different permutations to form programs, the largest of which is a 4-input AND gate that consists of 3 circuits that integrate 4 inducible systems, thus requiring 11 regulatory proteins. Measuring the performance of individual gates is sufficient to capture the behaviour of the complete program. Errors in the output due to delays (faults), a common problem for layered circuits, are not observed. This work demonstrates the successful layering of orthogonal logic gates, a design strategy that could enable the construction of large, integrated circuits in single cells.

  13. Feasibility of home infusion and self-administration of nanofiltered C1 esterase inhibitor for routine prophylaxis in patients with hereditary angioedema and characterization of a training and support program.

    PubMed

    Gregory, Cherylann; Landmesser, Ladonna M; Corrigan, Larry; Mariano, David

    2014-01-01

    Hereditary angioedema (HAE) is a rare, chronic disease of C1 inhibitor deficiency. Study researchers evaluated the prevalence of home and self-administration of nanofiltered, human-derived C1 esterase inhibitor infusions and the implementation of a nursing training and support program. Home administration rate increased from 49.0% to 75.8%. The percentage who self-administered increased from 20.3% to 43.9%. Doses per week averaged 1.85 at home compared with 1.40 in infusion centers and physicians' offices. Patients required an average of 5 visits to be trained. Self-administration is a viable, feasible option in the management of HAE, which is facilitated by a nurse-managed training and support program.

  14. Planning and scheduling highway construction using GIS and dynamic programming

    NASA Astrophysics Data System (ADS)

    Hassanein, Ahmed

    This study presents a model to plan, schedule and control the construction of highway projects. A two-state-variable, N-stage dynamic programming procedure, in conjunction with a set of heuristic rules, is capable of generating schedules to meet a specified budget or duration restraints, and can select the optimum expediting technique to reduce project duration. The proposed model incorporates both typical (equal quantity of work in all units) and non-typical (varying quantities along highway length) repetitive activities in the optimization procedure. The proposed model accounts for the impact of practical factors, such as transverse obstructions, on crew assignment and project duration and cost. The impact of inclement weather on crew productivity is accounted for, as well as the beneficial effects of the learning curve. A relational database model is developed to store: (1) local weather conditions, (2) swell and shrinkage factors for various soil types, and (3) the available resource pool. The model supports tracking and controlling project progress utilising the earned value concept. A flexible and practical methodology is proposed to forecast project time and cost at completion, enabling the assignment of a higher weight to recent crew performance. A prototype software based on the model is developed, coded in Visual C++ (version 6.0), employing object oriented programming. ArcViewRTM version 3.1 is employed as the GIS engine, and the 3-D data analysis is carried out employing ArcViewRTM 3D Analyst. (Abstract shortened by UMI.)

  15. Corporate Mentors and Undergraduate Students: A Qualitative Study of the Advancing Women in Construction Mentorship Program

    ERIC Educational Resources Information Center

    Eicher, Matthew

    2013-01-01

    In a conscious effort to combat the low enrollment of women in construction management, a program was created to retain women through a mentorship program--Advancing Women in Construction. A qualitative analysis, facilitated through a grounded theory approach, sought to understand if the program was indeed successful, and what value did the…

  16. Corporate Mentors and Undergraduate Students: A Qualitative Study of the Advancing Women in Construction Mentorship Program

    ERIC Educational Resources Information Center

    Eicher, Matthew

    2013-01-01

    In a conscious effort to combat the low enrollment of women in construction management, a program was created to retain women through a mentorship program--Advancing Women in Construction. A qualitative analysis, facilitated through a grounded theory approach, sought to understand if the program was indeed successful, and what value did the…

  17. 45 CFR 606.52 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SCIENCE FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL SCIENCE FOUNDATION § 606.52 Program accessibility: New construction and... 45 Public Welfare 3 2010-10-01 2010-10-01 false Program accessibility: New construction...

  18. 1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells

    SciTech Connect

    Asare, Nana Landvik, Nina E.; Lagadic-Gossmann, Dominique; Rissel, Mary; Tekpli, Xavier; Ask, Kjetil; Lag, Marit; Holme, Jorn A.

    2008-07-15

    Mechanistic studies of nitro-PAHs (polycyclic aromatic hydrocarbons) of interest might help elucidate which chemical characteristics are most important in eliciting toxic effects. 1-Nitropyrene (1-NP) is the predominant nitrated PAH emitted in diesel exhaust. 1-NP-exposed Hepa1c1c7 cells exhibited marked changes in cellular morphology, decreased proliferation and different forms of cell death. A dramatic increase in cytoplasmic vacuolization was observed already after 6 h of exposure and the cells started to round up at 12 h. The rate of cell proliferation was markedly reduced at 24 h and apoptotic as well as propidium iodide (PI)-positive cells appeared. Electron microscopic examination revealed that the vacuolization was partly due to mitochondria swelling. The caspase inhibitor Z-VAD-FMK inhibited only the apoptotic cell death and Nec-1 (an inhibitor of necroptosis) exhibited no inhibitory effects on either cell death or vacuolization. In contrast, cycloheximide markedly reduced both the number of apoptotic and PI-positive cells as well as the cytoplasmic vacuolization, suggesting that 1-NP induced paraptotic cell death. All the MAPKs; ERK1/2, p38 and JNK, appear to be involved in the death process since marked activation was observed upon 1-NP exposure, and their inhibitors partly reduced the induced cell death. The ERK1/2 inhibitor PD 98057 completely blocked the induced vacuolization, whereas the other MAPKs inhibitors only had minor effects on this process. These findings suggest that 1-NP may cause apoptosis and paraptosis. In contrast, the corresponding amine (1-aminopyrene) elicited only minor apoptotic and necrotic cell death, and cells with characteristics typical of paraptosis were absent.

  19. Viva Mulher: constructing a cervical cancer control program in Brazil.

    PubMed

    Porto, Marco Antonio; Habib, Paula Arantes Botelho Briglia

    2014-01-01

    Through a number of isolated initiatives that began in the 1960s, Brazil accumulated knowledge and experience that in the late 1990s culminated in the implementation of the first nationwide public health action meant to coordinate health bodies and personnel from the federal, state, and municipal administrative levels to address a chronic degenerative disease. The main goal of this article is to analyze the process of construction of this public policy for cancer control in Brazil--more specifically, organized screening for the control of cervical cancer in the form of the Viva Mulher program. Our analytical approach relies on elements from the history of public policy and from the history of institutions, combining the use of documental sources, scientific literature, and interviews with managers involved in the process under study. Our analysis endeavors to show how and to what extent this national process incorporated the experiences of local projects and responded both to pressure from the social movement and to the country's political environment. It further shows how the new context, shaped by changes in the organization of the Brazilian health system, influenced this process.

  20. Extravehicular Crewman Work System (ECWS) study program. Volume 2: Construction

    NASA Technical Reports Server (NTRS)

    Wilde, R. C.

    1980-01-01

    The construction portion of the Extravehicular Crewman Work System Study defines the requirements and selects the concepts for the crewman work system required to support the construction of large structures in space.

  1. 18 CFR 1313.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... TENNESSEE VALLEY AUTHORITY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE TENNESSEE VALLEY AUTHORITY § 1313.151 Program accessibility: New construction and...

  2. 32 CFR 1906.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... INTELLIGENCE AGENCY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE CENTRAL INTELLIGENCE AGENCY § 1906.151 Program accessibility: New construction and...

  3. Construction Management Guidelines for Capital Outlay Program Projects.

    ERIC Educational Resources Information Center

    Georgia State Dept. of Education, Atlanta. Facilities Services Unit.

    The Georgia State Department of Education recognizes two separate methods for utilizing construction management services by local school systems when state capital outlay funds are involved. This report details those two methods. The report first describes the Construction Management (CM)-Agency approach, which allows a CM-Agency manager to enter…

  4. Guidelines for Selecting a Construction Approach for Education Building Programs.

    ERIC Educational Resources Information Center

    Barton Malow Co., Southfield, MI.

    This book discusses the advantages and disadvantages of the two most common construction planning methods utilized for educational facilities: general contracting and construction management. Diagrams are provided that illustrate the chain of command and communication within each approach, and highlight considerations that every school district…

  5. Adults' Perceptions of Knowledge Construction as Participants in Nonformal World Affairs Programs: An Interpretive Study

    ERIC Educational Resources Information Center

    Yelich Biniecki, Susan M.

    2015-01-01

    The purpose of this interpretive research study was to explore how adult learners perceive they construct knowledge in connection to their participation in nonformal world affairs programs. The study context involved the exploration of 12 adult learners' perceptions of their knowledge construction as participants in world affairs programs held in…

  6. 22 CFR 1600.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Program accessibility: New construction and alterations. 1600.151 Section 1600.151 Foreign Relations JAPAN-UNITED STATES FRIENDSHIP COMMISSION ENFORCEMENT... STATES FRIENDSHIP COMMISSION § 1600.151 Program accessibility: New construction and alterations. Each...

  7. 22 CFR 1600.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Program accessibility: New construction and alterations. 1600.151 Section 1600.151 Foreign Relations JAPAN-UNITED STATES FRIENDSHIP COMMISSION ENFORCEMENT... STATES FRIENDSHIP COMMISSION § 1600.151 Program accessibility: New construction and alterations. Each...

  8. 22 CFR 1600.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Program accessibility: New construction and alterations. 1600.151 Section 1600.151 Foreign Relations JAPAN-UNITED STATES FRIENDSHIP COMMISSION ENFORCEMENT... STATES FRIENDSHIP COMMISSION § 1600.151 Program accessibility: New construction and alterations. Each...

  9. 22 CFR 1600.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Program accessibility: New construction and alterations. 1600.151 Section 1600.151 Foreign Relations JAPAN-UNITED STATES FRIENDSHIP COMMISSION ENFORCEMENT... STATES FRIENDSHIP COMMISSION § 1600.151 Program accessibility: New construction and alterations. Each...

  10. New Tactics for Building: Experience/Analysis/Recommendations from the Detroit Public Schools Construction Systems Program.

    ERIC Educational Resources Information Center

    Cleland, Wallace B., Ed.

    This study is focused on organizational and procedural aspects of the Construction Systems Program (CSP), a developmental/demonstration project. The report is derived principally from practical observations by 42 active participants (architects, engineers, contractors, construction managers, owner's staff) in a four-school pilot program. Also…

  11. 22 CFR 530.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Program accessibility: New construction and alterations. 530.151 Section 530.151 Foreign Relations BROADCASTING BOARD OF GOVERNORS ENFORCEMENT OF... GOVERNORS § 530.151 Program accessibility: New construction and alterations. Each building or part of a...

  12. 22 CFR 711.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Program accessibility: New construction and alterations. 711.151 Section 711.151 Foreign Relations OVERSEAS PRIVATE INVESTMENT CORPORATION ADMINISTRATIVE... THE OVERSEAS PRIVATE INVESTMENT CORPORATION § 711.151 Program accessibility: New construction and...

  13. 22 CFR 711.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Program accessibility: New construction and alterations. 711.151 Section 711.151 Foreign Relations OVERSEAS PRIVATE INVESTMENT CORPORATION ADMINISTRATIVE... THE OVERSEAS PRIVATE INVESTMENT CORPORATION § 711.151 Program accessibility: New construction and...

  14. 22 CFR 711.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Program accessibility: New construction and alterations. 711.151 Section 711.151 Foreign Relations OVERSEAS PRIVATE INVESTMENT CORPORATION ADMINISTRATIVE... THE OVERSEAS PRIVATE INVESTMENT CORPORATION § 711.151 Program accessibility: New construction and...

  15. 6 CFR 15.51 - Program accessibility; new construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 6 Domestic Security 1 2011-01-01 2011-01-01 false Program accessibility; new construction and alterations. 15.51 Section 15.51 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY... DEPARTMENT OF HOMELAND SECURITY § 15.51 Program accessibility; new construction and alterations....

  16. 6 CFR 15.51 - Program accessibility; new construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 6 Domestic Security 1 2012-01-01 2012-01-01 false Program accessibility; new construction and alterations. 15.51 Section 15.51 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY... DEPARTMENT OF HOMELAND SECURITY § 15.51 Program accessibility; new construction and alterations....

  17. 40 CFR 12.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Program accessibility: New construction and alterations. 12.151 Section 12.151 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... ENVIRONMENTAL PROTECTION AGENCY § 12.151 Program accessibility: New construction and alterations. Each...

  18. 40 CFR 12.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Program accessibility: New construction and alterations. 12.151 Section 12.151 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... ENVIRONMENTAL PROTECTION AGENCY § 12.151 Program accessibility: New construction and alterations. Each...

  19. Adults' Perceptions of Knowledge Construction as Participants in Nonformal World Affairs Programs: An Interpretive Study

    ERIC Educational Resources Information Center

    Yelich Biniecki, Susan M.

    2015-01-01

    The purpose of this interpretive research study was to explore how adult learners perceive they construct knowledge in connection to their participation in nonformal world affairs programs. The study context involved the exploration of 12 adult learners' perceptions of their knowledge construction as participants in world affairs programs held in…

  20. 18 CFR 1313.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Program accessibility: New construction and alterations. 1313.151 Section 1313.151 Conservation of Power and Water Resources... ACTIVITIES CONDUCTED BY THE TENNESSEE VALLEY AUTHORITY § 1313.151 Program accessibility: New construction and...

  1. A Solid Foundation: Key Capacities of Construction Pre-Apprenticeship Programs

    ERIC Educational Resources Information Center

    Helmer, Matt; Blair, Amy; Gerber, Allison

    2012-01-01

    This publication shares research from site visits conducted to construction pre-apprenticeship programs in Baltimore, Hartford, Milwaukee and Portland (OR). Findings from the site visits, which included interviews and focus groups with pre-apprenticeship program staff, public officials, philanthropic leaders, construction industry leaders and…

  2. 40 CFR 12.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Program accessibility: New construction and alterations. 12.151 Section 12.151 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... ENVIRONMENTAL PROTECTION AGENCY § 12.151 Program accessibility: New construction and alterations. Each...

  3. 40 CFR 12.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Program accessibility: New construction and alterations. 12.151 Section 12.151 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... ENVIRONMENTAL PROTECTION AGENCY § 12.151 Program accessibility: New construction and alterations. Each...

  4. The demise of residential new construction programs: Is there life after death?

    SciTech Connect

    Vine, E.L.

    1995-05-01

    Based on an evaluation of 10 residential new construction programs sponsored by investor-owned utilities in the US, the authors find that many of these programs are in dire straits and are in danger of being discontinued because they are not cost-effective. They believe that the cost-effectiveness of residential new construction programs can be improved by: (1) reducing program marketing costs and developing more effective marketing strategies; (2) promoting technologies and advanced building design practices significantly exceeding state and federal standards; (3) recognizing these programs` role in increasing compliance by participants with existing state building codes; and (4) obtaining an energy-savings credit for program spillover (market transformation) impacts. The issues involved in evaluating residential new construction programs will be challenging as evaluators attempt to quantify the savings from program spillover.

  5. Labor productivity in heavy construction: impact on synfuels program employment

    SciTech Connect

    Kusterer, K.C.

    1980-06-01

    This study focuses on variations in labor productivity in the heavy construction industry. Productivity is one of a number of factors likely to affect the speed and cost of constructing a synthetic fuels plant. The findings of this study are presented with reference to synthetic fuels plants, but they are relevant to other large energy facilities as well. The data were gathered through a detailed literature search and extensive in-depth interviews with consultants in heavy industrial construction, union officials, and management. In this manner the most important determinants of labor productivity were identified and ranked in terms of relative significance. The type of project under construction is the most important factor affecting the productivity of heavy construction labor. Projects characterized by the utility work syndrome are large, complex, relatively unique, highly regulated, and have cost-plus contracts and tight deadlines. Such projects generally have lower-than-average levels of labor productivity. Labor productivity is also lowered by worker and management morale problems, due to delays and design changes, and by high levels of unemployment among construction workers. Finally, boom town conditions, caused by workers moving to live near large projects located in rural areas, also are likely to result in below-average labor productivity.Synthetic fuels plants are likely to have a number of these identified characteristics. Consequently, the findings suggest that labor productivity may well be a problem for the timely development of an economically competitive synthetic fuels industry.

  6. An Approach to Effortless Construction of Program Animations

    ERIC Educational Resources Information Center

    Velazquez-Iturbide, J. Angel; Pareja-Flores, Cristobal; Urquiza-Fuentes, Jaime

    2008-01-01

    Program animation systems have not been as widely adopted by computer science educators as we might expect from the firm belief that they can help in enhancing computer science education. One of the most notable obstacles to their adoption is the considerable effort that the production of program animations represents for the instructor. We…

  7. An Approach to Effortless Construction of Program Animations

    ERIC Educational Resources Information Center

    Velazquez-Iturbide, J. Angel; Pareja-Flores, Cristobal; Urquiza-Fuentes, Jaime

    2008-01-01

    Program animation systems have not been as widely adopted by computer science educators as we might expect from the firm belief that they can help in enhancing computer science education. One of the most notable obstacles to their adoption is the considerable effort that the production of program animations represents for the instructor. We…

  8. Financial Awareness Education with Apprentices in the Australian Construction Industry: Program Evaluation

    ERIC Educational Resources Information Center

    Du Plessis, Karin; Green, Emma

    2013-01-01

    A financial awareness education program was implemented with construction industry apprentices in Victoria, Australia. The program included face-to-face delivery of education around a range of financial management issues that apprentices face as they begin their apprenticeship. The paper reports on an evaluation of the program, which included…

  9. "It's All Up to You": How Welfare-to-Work Educational Programs Construct Workforce Success

    ERIC Educational Resources Information Center

    Sandlin, Jennifer A.

    2004-01-01

    This article discusses how two welfare education programs construct workforce success. Discourse about success in these programs falls into two basic camps: an individual-based self-motivation perspective and an external, structural, socioeconomic perspective. Although the individualistic perspective adhered to by the programs came into conflict…

  10. 5 CFR 723.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Program accessibility: New construction and alterations. 723.151 Section 723.151 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT... IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE OFFICE OF PERSONNEL MANAGEMENT § 723.151 Program...

  11. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Program accessibility: New construction and alterations. 2490.151 Section 2490.151 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES... PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151 Program...

  12. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Program accessibility: New construction and alterations. 2490.151 Section 2490.151 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES... PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151 Program...

  13. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 4 2012-10-01 2012-10-01 false Program accessibility: New construction and alterations. 2490.151 Section 2490.151 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES... PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151 Program...

  14. Financial Awareness Education with Apprentices in the Australian Construction Industry: Program Evaluation

    ERIC Educational Resources Information Center

    Du Plessis, Karin; Green, Emma

    2013-01-01

    A financial awareness education program was implemented with construction industry apprentices in Victoria, Australia. The program included face-to-face delivery of education around a range of financial management issues that apprentices face as they begin their apprenticeship. The paper reports on an evaluation of the program, which included…

  15. Utility residential new construction programs: Going beyond the code. A report from the Database on Energy Efficiency Programs (DEEP) Project

    SciTech Connect

    Vine, E.

    1995-08-01

    Based on an evaluation of 10 residential new construction programs, primarily sponsored by investor-owned utilities in the United States, we find that many of these programs are in dire straits and are in danger of being discontinued because current inclusion of only direct program effects leads to the conclusion that they are not cost-effective. We believe that the cost-effectiveness of residential new construction programs can be improved by: (1) promoting technologies and advanced building design practices that significantly exceed state and federal standards; (2) reducing program marketing costs and developing more effective marketing strategies; (3) recognizing the role of these programs in increasing compliance with existing state building codes; and (4) allowing utilities to obtain an ``energy-savings credit`` from utility regulators for program spillover (market transformation) impacts. Utilities can also leverage their resources in seizing these opportunities by forming strong and trusting partnerships with the building community and with local and state government.

  16. Constructing a Family Literacy Program: Challenges and Successes

    ERIC Educational Resources Information Center

    Jay, Jenny; Rohl, Mary

    2005-01-01

    This paper describes a family literacy project that involved parents whose children were attending a pre-school centre in a low socio-economic suburb of Perth, Western Australia. A formative experimental design was used to examine the home literacy practices of the families as described by the parents, and to construct a series of workshops. The…

  17. Algorithm for constructing the programmed motion of a bounding vehicle for the flight phase

    NASA Technical Reports Server (NTRS)

    Lapshin, V. V.

    1979-01-01

    The construction of the programmed motion of a multileg bounding vehicle in the flight was studied. An algorithm is given for solving the boundary value problem for constructing this programmed motion. If the motion is shown to be symmetrical, a simplified use of the algorithm can be applied. A method is proposed for nonimpact of the legs during lift-off of the vehicle, and for softness at touchdown. Tables are utilized to construct this programmed motion over a broad set of standard motion conditions.

  18. MixtureTree: a program for constructing phylogeny.

    PubMed

    Chen, Shu-Chuan; Rosenberg, Michael S; Lindsay, Bruce G

    2011-04-21

    MixtureTree v1.0 is a Linux based program (written in C++) which implements an algorithm based on mixture models for reconstructing phylogeny from binary sequence data, such as single-nucleotide polymorphisms (SNPs). In addition to the mixture algorithm with three different optimization options, the program also implements a bootstrap procedure with majority-rule consensus. The MixtureTree program written in C++ is a Linux based package. The User's Guide and source codes will be available at http://math.asu.edu/~scchen/MixtureTree.html The efficiency of the mixture algorithm is relatively higher than some classical methods, such as Neighbor-Joining method, Maximum Parsimony method and Maximum Likelihood method. The shortcoming of the mixture tree algorithms, for example timing consuming, can be improved by implementing other revised Expectation-Maximization(EM) algorithms instead of the traditional EM algorithm.

  19. Automated Construction Management System (ACMS). Volume 2. Program Documentation.

    DTIC Science & Technology

    1984-06-01

    fe -e !t !a’.*I - . I’ q . .% % .. -S C .. .. .. .. .. .. .. . .. . 19 BAC UP CM . . oo o .. .. s.. .. .. . o.. s .. .. . . . . 197 WP . M s . . . . .s...USE RETURN * * *END BACKUP.CMD 26**. *% A C M S Ver. 84.0 ’ * USA-CERL PROGRAM: BILL.CMD " * DESCRIPTION: This program allows the user to set up ...11,0 SAY "Schedules Included: " ?? " <Type CTR-Q to abort>" SELECT SECOND STORE 12 TO row STORE 0 TO col * up to 80 schedules can be displayed on

  20. Construction safety program for the National Ignition Facility, Appendix B

    SciTech Connect

    Cerruti, S.J.

    1997-06-26

    This Appendix contains material from the LLNL Health and Safety Manual as listed below. For sections not included in this list, please refer to the Manual itself. The areas covered are: asbestos, lead, fire prevention, lockout, and tag program confined space traffic safety.

  1. Construction Management Program Builds Financial Development from the Ground up

    ERIC Educational Resources Information Center

    Nobe, Michael D.; Shuler, Scott; Grosse, Larry

    2007-01-01

    Recent economic and legislative changes have hit higher education hard and threaten the financial viability of many educational programs nationwide. With state support dwindling to less than 10 percent in some cases, institutions across the nation face a financial crisis. Many strategies have been explored and implemented, from campaigns to…

  2. Constructing and Implementing a Model Juvenile Diversion Program.

    ERIC Educational Resources Information Center

    Pogrebin, Mark R.; And Others

    1984-01-01

    One approach to handling juvenile offenders is the diversion of youth away from formal contact with the juvenile justice system. A diversion program implemented in Adams County, Colorado, is described here. Objectives were to reduce court caseloads, lower recidivism rates, lessen the net of social control, and permit rigorous evaluation. (GC)

  3. Constructing a conflict resolution program for health care.

    PubMed

    Porter-O'Grady, Tim

    2004-01-01

    Resolving conflict throughout organizations requires a programmatic infrastructure and a committed management team. Leaders must recognize the need to approach conflict by building a format for learning, creating and managing an effective conflict management program. Careful attention to the elements of design and the stages of development can make all the difference in building a sustainable and useful conflict management approach.

  4. Rationale for the Cultural Construction of School Mental Health Programming

    ERIC Educational Resources Information Center

    Arora, Prerna G.; Nastasi, Bonnie K.; Leff, Stephen S.

    2017-01-01

    The implementation of evidence-based psychological programming to meet the needs of a global population has been impeded by the translation of theories and research findings across populations and settings without due consideration of cultural factors. The purpose of this article is to discuss the rationale for use of partnership-based methods in…

  5. Construction safety program for the National Ignition Facility, Appendix A

    SciTech Connect

    Cerruti, S.J.

    1997-06-26

    Topics covered in this appendix include: General Rules-Code of Safe Practices; 2. Personal Protective Equipment; Hazardous Material Control; Traffic Control; Fire Prevention; Sanitation and First Aid; Confined Space Safety Requirements; Ladders and Stairways; Scaffolding and Lift Safety; Machinery, Vehicles, and Heavy Equipment; Welding and Cutting-General; Arc Welding; Oxygen/Acetylene Welding and Cutting; Excavation, Trenching, and Shoring; Fall Protection; Steel Erection; Working With Asbestos; Radiation Safety; Hand Tools; Electrical Safety; Nonelectrical Work Performed Near Exposed High-Voltage Power-Distribution Equipment; Lockout/Tagout Requirements; Rigging; A-Cranes; Housekeeping; Material Handling and Storage; Lead; Concrete and Masonry Construction.

  6. 38 CFR 15.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Program accessibility: New construction and alterations. 15.151 Section 15.151 Pensions, Bonuses, and Veterans' Relief... and alterations. Each building or part of a building that is constructed or altered by, on behalf...

  7. 38 CFR 15.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Program accessibility: New construction and alterations. 15.151 Section 15.151 Pensions, Bonuses, and Veterans' Relief... and alterations. Each building or part of a building that is constructed or altered by, on behalf...

  8. RECOMMENDED FOUNDATION FILL MATERIALS CONSTRUCTION STANDARD OF THE FLORIDA RADON RESEARCH PROGRAM

    EPA Science Inventory

    The report summarizes the technical basis for a recommended foundation fill materials standard for new construction houses in Florida. he radon-control construction standard was developed by the Florida Radon Research Program (FRRP). ill material standards are formulated for: (1)...

  9. 36 CFR 1154.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... construction and alterations. 1154.151 Section 1154.151 Parks, Forests, and Public Property ARCHITECTURAL AND... ACTIVITIES CONDUCTED BY THE ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD § 1154.151 Program... altered by, on behalf of, or for the use of the agency shall be designed, constructed, or altered so as to...

  10. 25 CFR 1000.255 - May a Tribe/Consortium reallocate funds among construction programs?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false May a Tribe/Consortium reallocate funds among... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.255 May a Tribe/Consortium reallocate funds among construction programs? Yes, a Tribe/Consortium may reallocate funds among...

  11. 25 CFR 1000.255 - May a Tribe/Consortium reallocate funds among construction programs?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false May a Tribe/Consortium reallocate funds among... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.255 May a Tribe/Consortium reallocate funds among construction programs? Yes, a Tribe/Consortium may reallocate funds among...

  12. 25 CFR 1000.255 - May a Tribe/Consortium reallocate funds among construction programs?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false May a Tribe/Consortium reallocate funds among... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.255 May a Tribe/Consortium reallocate funds among construction programs? Yes, a Tribe/Consortium may reallocate funds among...

  13. 25 CFR 1000.255 - May a Tribe/Consortium reallocate funds among construction programs?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false May a Tribe/Consortium reallocate funds among... INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.255 May a Tribe/Consortium reallocate funds among construction programs? Yes, a Tribe/Consortium may reallocate funds among...

  14. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true Program accessibility: New construction and alterations. 51-10.151 Section 51-10.151 Public Contracts and Property Management... altered by, on behalf of, or for the use of the agency shall be designed, constructed, or altered so as...

  15. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 1 2014-07-01 2014-07-01 false Program accessibility: New construction and alterations. 51-10.151 Section 51-10.151 Public Contracts and Property Management... altered by, on behalf of, or for the use of the agency shall be designed, constructed, or altered so as...

  16. 45 CFR 1153.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) NATIONAL FOUNDATION ON THE ARTS AND THE HUMANITIES NATIONAL ENDOWMENT FOR THE ARTS ENFORCEMENT OF... ARTS § 1153.151 Program accessibility: New construction and alterations. Each building or part of a..., constructed, or altered so as to be readily accessible to and usable by handicapped persons. The definitions...

  17. RECOMMENDED FOUNDATION FILL MATERIALS CONSTRUCTION STANDARD OF THE FLORIDA RADON RESEARCH PROGRAM

    EPA Science Inventory

    The report summarizes the technical basis for a recommended foundation fill materials standard for new construction houses in Florida. he radon-control construction standard was developed by the Florida Radon Research Program (FRRP). ill material standards are formulated for: (1)...

  18. 25 CFR 1000.255 - May a Tribe/Consortium reallocate funds among construction programs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... construction programs? 1000.255 Section 1000.255 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.255 May a Tribe/Consortium...

  19. Construction: Carpentry Concentration. Program CIP: 46.0000 Construction: Carpentry Concentration

    ERIC Educational Resources Information Center

    Agee, Kelly, Ed.

    2008-01-01

    Secondary vocational-technical education programs in Mississippi are faced with many challenges resulting from sweeping educational reforms at the national and state levels. Schools and teachers are increasingly being held accountable for providing true learning activities to every student in the classroom. This accountability is measured through…

  20. 7 CFR 15e.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Program accessibility: New construction and alterations. 15e.151 Section 15e.151 Agriculture Office of the Secretary of Agriculture ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE UNITED STATES DEPARTMENT...

  1. 7 CFR 15e.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 1 2013-01-01 2013-01-01 false Program accessibility: New construction and alterations. 15e.151 Section 15e.151 Agriculture Office of the Secretary of Agriculture ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE UNITED STATES DEPARTMENT...

  2. 22 CFR 1600.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Program accessibility: New construction and alterations. 1600.151 Section 1600.151 Foreign Relations JAPAN-UNITED STATES FRIENDSHIP COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAPAN-UNITED...

  3. 77 FR 28573 - Applications for New Awards; Impact Aid Discretionary Construction Grant Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-15

    ... Applications for New Awards; Impact Aid Discretionary Construction Grant Program AGENCY: Office of Elementary and Secondary Education, Department of Education ACTION: Notice. Overview Information Impact Aid... 11, 2012. Full Text of Announcement I. Funding Opportunity Description Purpose of Program: The Impact...

  4. 22 CFR 219.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... alterations. 219.151 Section 219.151 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY INTERNATIONAL DEVELOPMENT COOPERATION AGENCY, AGENCY FOR INTERNATIONAL DEVELOPMENT § 219.151 Program accessibility: New construction and...

  5. Constructing a Self-Funded Program Takes More than Just Dollars and Cents

    ERIC Educational Resources Information Center

    Burke, Scott

    2012-01-01

    With a little ingenuity and a lot of dedication, the author created a self-funded construction program that is weathering the ups and downs of school funding; it enjoys great support from the community, is accomplishing more with less, and collaborative efforts between teachers are paying off. Creating such a program takes time, vision,…

  6. Constructing a Self-Funded Program Takes More than Just Dollars and Cents

    ERIC Educational Resources Information Center

    Burke, Scott

    2012-01-01

    With a little ingenuity and a lot of dedication, the author created a self-funded construction program that is weathering the ups and downs of school funding; it enjoys great support from the community, is accomplishing more with less, and collaborative efforts between teachers are paying off. Creating such a program takes time, vision,…

  7. LEAF: A Microcomputer Program for Constructing the Tukey Stem and Leaf Graph.

    ERIC Educational Resources Information Center

    Pascale, Pietro J.; Smith, Joseph

    1986-01-01

    This paper presents a BASIC microcomputer program that constructs the Tukey (1977) stem and leaf graph. Options within the LEAF program include a modified stem and leaf where the stem is split and a parallel stem and leaf graph where two separate sets of data are displayed from a common stem. (Author)

  8. Programs for the Construction and Analysis of Custom Questionnaires and Rating Scales

    ERIC Educational Resources Information Center

    Doyle, Kenneth O., Jr.; Wattawa, Scott

    1977-01-01

    Programs are described for the construction and analysis of student evaluation questionnaires and rating scales that are custom-designed for individual course instructors. Minor modifications would permit the use of these programs for other kinds of questionnaires and rating scales as well as for achievement tests. (Author)

  9. 22 CFR 530.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Program accessibility: New construction and alterations. 530.151 Section 530.151 Foreign Relations BROADCASTING BOARD OF GOVERNORS ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE BROADCASTING BOARD...

  10. 19 CFR 201.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Program accessibility: New construction and alterations. 201.151 Section 201.151 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES... Activities Conducted by the U.S. International Trade Commission § 201.151 Program accessibility: New...

  11. 45 CFR 1214.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Program accessibility: New construction and alterations. 1214.151 Section 1214.151 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY...

  12. 17 CFR 200.651 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Program accessibility: New construction and alterations. 200.651 Section 200.651 Commodity and Securities Exchanges SECURITIES AND... Nondiscrimination on the Basis of Handicap in Programs or Activities Conducted by the Securities and...

  13. 17 CFR 200.651 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Program accessibility: New construction and alterations. 200.651 Section 200.651 Commodity and Securities Exchanges SECURITIES AND... Nondiscrimination on the Basis of Handicap in Programs or Activities Conducted by the Securities and...

  14. 17 CFR 200.651 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Program accessibility: New construction and alterations. 200.651 Section 200.651 Commodity and Securities Exchanges SECURITIES AND... Nondiscrimination on the Basis of Handicap in Programs or Activities Conducted by the Securities and...

  15. 19 CFR 201.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 3 2011-04-01 2011-04-01 false Program accessibility: New construction and alterations. 201.151 Section 201.151 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION GENERAL RULES OF GENERAL APPLICATION Enforcement of Nondiscrimination on the Basis of Handicap in Programs...

  16. Adopter's Guide for Planning, Developing and Implementing a Model Construction Cluster Program.

    ERIC Educational Resources Information Center

    Beaverton School District 48, OR.

    This guide contains processes for planning, developing, and implementing an industry-based construction cluster program in Oregon secondary schools. Each process was pilot tested and revised by Beaverton School District during the development of a model program at Beaverton High School. The guide is intended to help other school districts…

  17. 45 CFR 606.52 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SCIENCE FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL SCIENCE FOUNDATION § 606.52 Program accessibility: New construction and... usable by individuals with handicaps. The definitions, requirements, and standards of the Architectural...

  18. Highway Safety Program Manual: Volume 12: Highway Design, Construction and Maintenance.

    ERIC Educational Resources Information Center

    National Highway Traffic Safety Administration (DOT), Washington, DC.

    Volume 12 of the 19-volume Highway Safety Program Manual (which provides guidance to State and local governments on preferred highway safety practices) focuses on highway design, construction and maintenance. The purpose and specific objectives of such a program are described. Federal authority in the area of highway safety and policies regarding…

  19. 45 CFR 606.52 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SCIENCE FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE NATIONAL SCIENCE FOUNDATION § 606.52 Program accessibility: New construction and... usable by individuals with handicaps. The definitions, requirements, and standards of the Architectural...

  20. 45 CFR 1803.8 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Program accessibility: New construction and alterations. 1803.8 Section 1803.8 Public Welfare Regulations Relating to Public Welfare (Continued) HARRY S. TRUMAN SCHOLARSHIP FOUNDATION NONDISCRIMINATION ON THE BASIS OF HANDICAP § 1803.8 Program accessibility...

  1. 75 FR 60263 - Federal Acquisition Regulation; Offering a Construction Requirement-8(a) Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ... Federal Acquisition Regulation; Offering a Construction Requirement--8(a) Program AGENCIES: Department of... Regulations Council (Councils) are issuing a final rule amending the Federal Acquisition Regulation (FAR) to revise FAR subpart 19.8, Contracting with the Small Business Administration (The 8(a) Program), to...

  2. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 11 2014-10-01 2014-10-01 false Program accessibility: New construction and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE MAMMAL...

  3. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 11 2013-10-01 2013-10-01 false Program accessibility: New construction and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE MAMMAL...

  4. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 11 2012-10-01 2012-10-01 false Program accessibility: New construction and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE MAMMAL...

  5. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Program accessibility: New construction and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE MAMMAL...

  6. 45 CFR 2301.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) ARCTIC RESEARCH COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE UNITED STATES ARCTIC RESEARCH COMMISSION § 2301.151 Program accessibility: New... of, or for the use of the agency shall be designed, constructed, or altered so as to be...

  7. 43 CFR 17.551 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Program accessibility: New construction and alterations. 17.551 Section 17.551 Public Lands: Interior Office of the Secretary of the Interior NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OF THE DEPARTMENT OF THE INTERIOR Enforcement of...

  8. Creswell's Energy Efficient Construction Program: A Big Project for a Small School.

    ERIC Educational Resources Information Center

    Kelsh, Bruce

    1982-01-01

    In Creswell (Oregon) High School's award winning vocational education program, students study energy efficient construction along with basic building skills. Part of the program has been the active recruitment of female, minority, disadvantaged, and handicapped students into the vocational area. Students have assembled solar hot water collectors,…

  9. 22 CFR 1005.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Program accessibility: New construction and alterations. 1005.151 Section 1005.151 Foreign Relations INTER-AMERICAN FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE INTER-AMERICAN...

  10. 22 CFR 1510.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Program accessibility: New construction and alterations. 1510.151 Section 1510.151 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE AFRICAN DEVELOPMENT...

  11. 50 CFR 550.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Program accessibility: New construction and alterations. 550.151 Section 550.151 Wildlife and Fisheries MARINE MAMMAL COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY MARINE MAMMAL...

  12. Item Pool Construction Using Mixed Integer Quadratic Programming (MIQP). GMAC® Research Report RR-14-01

    ERIC Educational Resources Information Center

    Han, Kyung T.; Rudner, Lawrence M.

    2014-01-01

    This study uses mixed integer quadratic programming (MIQP) to construct multiple highly equivalent item pools simultaneously, and compares the results from mixed integer programming (MIP). Three different MIP/MIQP models were implemented and evaluated using real CAT item pool data with 23 different content areas and a goal of equal information…

  13. 25 CFR 170.404 - What happens when a tribe uses its IRR Program construction funds for transportation planning?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What happens when a tribe uses its IRR Program... tribe uses its IRR Program construction funds for transportation planning? In order for IRR Program... percent of its IRR Program construction funds, whichever is greater, for transportation planning. If...

  14. MATES in Construction: Impact of a Multimodal, Community-Based Program for Suicide Prevention in the Construction Industry

    PubMed Central

    Gullestrup, Jorgen; Lequertier, Belinda; Martin, Graham

    2011-01-01

    A large-scale workplace-based suicide prevention and early intervention program was delivered to over 9,000 construction workers on building sites across Queensland. Intervention components included universal General Awareness Training (GAT; general mental health with a focus on suicide prevention); gatekeeper training provided to construction worker volunteer ‘Connectors’; Suicide First Aid (ASIST) training offered to key workers; outreach support provided by trained and supervised MIC staff; state-wide suicide prevention hotline; case management service; and postvention support provided in the event of a suicide. Findings from over 7,000 workers (April 2008 to November 2010) are reported, indicating strong construction industry support, with 67% building sites and employers approached agreeing to participate in MIC. GAT participants demonstrated significantly increased suicide prevention awareness compared with a comparison group. Connector training participants rated MIC as helpful and effective, felt prepared to intervene with a suicidal person, and knew where to seek help for a suicidal individual following the training. Workers engaged positively with the after-hours crisis support phone line and case management. MIC provided postvention support to 10 non-MIC sites and sites engaged with MIC, but not yet MIC-compliant. Current findings support the potential effectiveness and social validity of MIC for preventing suicide in construction workers. PMID:22163201

  15. MATES in construction: impact of a multimodal, community-based program for suicide prevention in the construction industry.

    PubMed

    Gullestrup, Jorgen; Lequertier, Belinda; Martin, Graham

    2011-11-01

    A large-scale workplace-based suicide prevention and early intervention program was delivered to over 9,000 construction workers on building sites across Queensland. Intervention components included universal General Awareness Training (GAT; general mental health with a focus on suicide prevention); gatekeeper training provided to construction worker volunteer 'Connectors'; Suicide First Aid (ASIST) training offered to key workers; outreach support provided by trained and supervised MIC staff; state-wide suicide prevention hotline; case management service; and postvention support provided in the event of a suicide. Findings from over 7,000 workers (April 2008 to November 2010) are reported, indicating strong construction industry support, with 67% building sites and employers approached agreeing to participate in MIC. GAT participants demonstrated significantly increased suicide prevention awareness compared with a comparison group. Connector training participants rated MIC as helpful and effective, felt prepared to intervene with a suicidal person, and knew where to seek help for a suicidal individual following the training. Workers engaged positively with the after-hours crisis support phone line and case management. MIC provided postvention support to 10 non-MIC sites and sites engaged with MIC, but not yet MIC-compliant. Current findings support the potential effectiveness and social validity of MIC for preventing suicide in construction workers.

  16. COOPERATIVE RESEARCH IN C1 CHEMISTRY

    SciTech Connect

    Gerald P. Huffman

    2001-04-30

    Faculty and students from five universities (Kentucky, West Virginia, Utah, Pittsburgh and Auburn) are collaborating on a basic research program to develop novel C1 chemistry processes for the production of clean, high quality transportation fuel. An Industrial Advisory Board (IAB) with members from Chevron, Eastman Chemical, Energy International, Teir Associates, and the Department of Defense has been formed to provide practical guidance to the program. The program has two principal objectives. (1) Develop technology for conversion of C1 source materials (natural gas, synthesis gas, carbon dioxide and monoxide, and methanol) into clean, high efficiency transportation fuel. (2) Develop novel processes for producing hydrogen from natural gas and other hydrocarbons. Some of the principal accomplishments of the program in its first two years are: (1) The addition of acetylenic compounds in Fischer-Tropsch synthesis is found to produce significant amounts of oxygenated products in FT diesel fuels. Such oxygenated products should decrease particulate matter (PM) emissions. (2) Nanoscale, binary, Fe-based catalysts supported on alumina have been shown to have significant activity for the decomposition of methane into pure hydrogen and potentially valuable multi-walled carbon nanotubes. (3) Catalytic synthesis processes have been developed for synthesis of diethyl carbonate, higher ethers, and higher alcohols from C1 source materials. Testing of the effect of adding these oxygenates to diesel fuel on PM emissions has begun using a well-equipped small diesel engine test facility. (4) Supercritical fluid (SCF) FT synthesis has been conducted under SCF hexane using both Fe and Co catalysts. There is a marked effect on the hydrocarbon product distribution, with a shift to higher carbon number products. These and other results are summarized.

  17. Accurate construction of consensus genetic maps via integer linear programming.

    PubMed

    Wu, Yonghui; Close, Timothy J; Lonardi, Stefano

    2011-01-01

    We study the problem of merging genetic maps, when the individual genetic maps are given as directed acyclic graphs. The computational problem is to build a consensus map, which is a directed graph that includes and is consistent with all (or, the vast majority of) the markers in the input maps. However, when markers in the individual maps have ordering conflicts, the resulting consensus map will contain cycles. Here, we formulate the problem of resolving cycles in the context of a parsimonious paradigm that takes into account two types of errors that may be present in the input maps, namely, local reshuffles and global displacements. The resulting combinatorial optimization problem is, in turn, expressed as an integer linear program. A fast approximation algorithm is proposed, and an additional speedup heuristic is developed. Our algorithms were implemented in a software tool named MERGEMAP which is freely available for academic use. An extensive set of experiments shows that MERGEMAP consistently outperforms JOINMAP, which is the most popular tool currently available for this task, both in terms of accuracy and running time. MERGEMAP is available for download at http://www.cs.ucr.edu/~yonghui/mgmap.html.

  18. If you've seen one construction worksite stretch and flex program … you've seen one construction worksite stretch and flex program.

    PubMed

    Goldenhar, Linda M; Stafford, Pete

    2015-12-01

    Work-related Musculoskeletal Disorders (WMSD) account for approximately one-third of all injuries in the U.S. construction industry. Many companies have implemented stretch and flex (s/f) programs to reduce WMSD despite a lack of evidence showing effectiveness. We conducted a mixed-methods study to understand (a) why employers continue devoting resources to s/f programs; (b) how programs vary; and (c) any actual or perceived benefits. Nineteen safety and health professionals were interviewed and 133 more (13.3% response rate) completed an on-line survey. Fifty-six percent had implemented an s/f program with the primary goal of reducing WMSDs; though most did not review data to determine goal achievement. Program structure varied in terms of duration, frequency, and type of stretches. There was strong agreement about mandating attendance but not participation, due primarily to liability issues. Cost was a factor when deciding to implement a program but not for sustaining one. The majority had not implemented other ergonomic prevention activities, but many had started conducting daily safety huddles for task and safety planning. Those reporting a reduction in WMSDs agreed that it was not due to the s/f program alone and that other benefits included increased worker camaraderie, communication, and collaboration. Although there is little to no scientific evidence showing that they work as intended, construction companies continue to implement s/f programs with the goal of reducing WMSDs. Bringing work crews together for s/f activities has prompted employers to also begin conducting daily safety huddles. Although employers may not be able to link reduced WMDS to an s/f program, the ancillary benefits may warrant the time and resources. S/f programs should be only one component of a more comprehensive ergonomics prevention program. Conducting daily safety huddles at the same time also may enhance worker communication, camaraderie, collaboration and improve safety

  19. 25 CFR 1000.240 - What construction programs included in an AFA are subject to this subpart?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 2 2012-04-01 2012-04-01 false What construction programs included in an AFA are subject... in an AFA are subject to this subpart? (a) All BIA and non-BIA construction programs included in an AFA are subject to this subpart. This includes design, construction, repair, improvement,...

  20. 25 CFR 1000.240 - What construction programs included in an AFA are subject to this subpart?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 2 2011-04-01 2011-04-01 false What construction programs included in an AFA are subject... in an AFA are subject to this subpart? (a) All BIA and non-BIA construction programs included in an AFA are subject to this subpart. This includes design, construction, repair, improvement,...

  1. 25 CFR 1000.240 - What construction programs included in an AFA are subject to this subpart?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 2 2014-04-01 2014-04-01 false What construction programs included in an AFA are subject... in an AFA are subject to this subpart? (a) All BIA and non-BIA construction programs included in an AFA are subject to this subpart. This includes design, construction, repair, improvement,...

  2. 25 CFR 1000.240 - What construction programs included in an AFA are subject to this subpart?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 2 2013-04-01 2013-04-01 false What construction programs included in an AFA are subject... in an AFA are subject to this subpart? (a) All BIA and non-BIA construction programs included in an AFA are subject to this subpart. This includes design, construction, repair, improvement,...

  3. Software for C1 interpolation

    NASA Technical Reports Server (NTRS)

    Lawson, C. L.

    1977-01-01

    The problem of mathematically defining a smooth surface, passing through a finite set of given points is studied. Literature relating to the problem is briefly reviewed. An algorithm is described that first constructs a triangular grid in the (x,y) domain, and first partial derivatives at the modal points are estimated. Interpolation in the triangular cells using a method that gives C sup.1 continuity overall is examined. Performance of software implementing the algorithm is discussed. Theoretical results are presented that provide valuable guidance in the development of algorithms for constructing triangular grids.

  4. Cooperative Research in C1 Chemistry

    SciTech Connect

    Gerald P. Huffman

    2000-10-27

    C1 chemistry refers to the conversion of simple carbon-containing materials that contain one carbon atom per molecule into valuable products. The feedstocks for C1 chemistry include natural gas, carbon dioxide, carbon monoxide, methanol and synthesis gas (a mixture of carbon monoxide and hydrogen). Synthesis gas, or syngas, is produced primarily by the reaction of natural gas, which is principally methane, with steam. It can also be produced by gasification of coal, petroleum coke, or biomass. The availability of syngas from coal gasification is expected to increase significantly in the future because of increasing development of integrated gasification combined cycle (IGCC) power generation. Because of the abundance of remote natural gas, the advent of IGCC, and environmental advantages, C1 chemistry is expected to become a major area of interest for the transportation fuel and chemical industries in the relatively near future. The CFFLS will therefore perform a valuable national service by providing science and engineering graduates that are trained in this important area. Syngas is the source of most hydrogen. Approximately 10 trillion standard cubic feet (SCF) of hydrogen are manufactured annually in the world. Most of this hydrogen is currently used for the production of ammonia and in a variety of refining and chemical operations. However, utilization of hydrogen in fuel cells is expected to grow significantly in the next century. Syngas is also the feedstock for all methanol and Fischer-Tropsch plants. Currently, world consumption of methanol is over 25 million tons per year. There are many methanol plants in the U.S. and throughout the world. Methanol and oxygenated transportation fuel products play a significant role in the CFFLS C1 program. Currently, the only commercial Fischer-Tropsch plants are overseas, principally in South Africa (SASOL). However, new plants are being built or planned for a number of locations. One possible location for future F

  5. C1 repressor-mediated DNA looping is involved in C1 autoregulation of bacteriophage P1.

    PubMed

    Heinzel, T; Lurz, R; Dobrinski, B; Velleman, M; Schuster, H

    1994-12-16

    C1 repressor is required to repress the lytic functions of a P1 prophage in vivo. Transcription of the c1 gene is autoregulated via the C1-controlled operator Op99a,b which overlaps the promoter of the c1 gene. It is negatively affected by Lxc corepressor and the DNA region upstream of c1, which contains the additional operators Op99c, d, and e. We have explored these effects by constructing a set of lacZ reporter plasmids with Op99a,b and varying parts of the upstream DNA region. Transcription levels were measured in vivo with a two-plasmid system containing the lacZ reporter and a c1+ lxc+ or c1+ lxc- plasmid. Compared to the C1+Lxc-repressed lacZ reporter with all operators present, the basal level of beta-galactosidase activity increases successively when (i) upstream operators were deleted or inactivated, (ii) Lxc corepressor was removed, and (iii) C1 and Lxc were absent. By that means a 2 x 2 x 15-fold stepwise increase in enzyme activity was found. Using electron microscopy to visualize the interaction of C1 repressor with the operators in vitro, looped DNA molecules were observed. Although all operators can participate in C1-mediated DNA looping, loops between Op99a,b and Op99d occurred predominantly. Lxc is not required but increases drastically the frequency of loop formation. The results indicate that C1-mediated DNA looping may be a second element besides Lxc for fine-tuning the autoregulation of c1 transcription.

  6. Construction

    DTIC Science & Technology

    2002-01-01

    Harbor Deepening Project, Jacksonville, FL Palm Valley Bridge Project, Jacksonville, FL Rotary Club of San Juan, San Juan, PR Tren Urbano Subway...David. What is nanotechnology? What are its implications for construction?, Foresight/CRISP Workshop on Nanotechnology, Royal Society of Arts

  7. Construction

    DTIC Science & Technology

    2002-01-01

    San Juan, PR Tren Urbano Subway Project, San Juan, PR U.S. Army South, San Juan, PR U.S. Coast Guard Housing Project, San Juan, PR U.S. Coast Guard...construction?, Foresight/CRISP Workshop on Nanotechnology, Royal Society of Arts . Cheltenham, England: 2001, p.5. 56 Concrete Proposals, Economist, July 24

  8. Molecular genetics of C1 inhibitor.

    PubMed

    Tosi, M

    1998-08-01

    More than 100 different C1 inhibitor gene mutations have been described in hereditary angioedema (HAE) patients. Sixty-nine mutations have been reported in patients with the quantitative C1 inhibitor defect (type 1 HAE) in two recent large-scale studies. These changes were found distributed over all exons and exon/intron boundaries. The molecular defects can be divided as follows: Alu-repeat-mediated deletions or duplications (accounting for 21% of all cases), missense mutations (> 36%), frameshifts (14%), Stop codon mutations (10%), promoter variants (4%), splice site mutations (7-10%), deletions of a few amino acids (less than 3%). Several recent studies indicate that up to 25% of these changes are found in patients without a family history of angioedema and represent de novo mutations. Pathogenic amino acid substitutions were found distributed over the entire length of the coding sequence, except for the 100 amino-acid-long glycosylated amino-terminal extension, whose sequence tolerates extensive variation, as indicated by comparisons across species. Functional studies have been carried out only on a fraction of these amino acid substitutions and indicate that defects affecting intracellular transport are often at the basis of type 1 hereditary angioedema. An interesting promoter variant (a C to T transition at position -103) was found in an exceptional family with recessive transmission of the disease. Regulatory elements in the promoter region and in intron 1 were revealed by their sequence conservation in mouse and man and by functional studies. C1 inhibitor "minigene" constructs directing correct mRNA and protein synthesis in transgenic mice have provided valuable information on hormonal control and cell-type specificity of gene expression.

  9. Programming for the Internet and Experiential Learning: A New Approach Incorporating a Constructed World

    ERIC Educational Resources Information Center

    Taylor, Adam P. R.

    2007-01-01

    This paper reports on a novel approach taken by the author to the teaching of an Internet programming course targeted at final year diploma and second year degree students. The uniqueness of engineers and their identity is discussed, as is the self-constructed world and ways of knowing in which humankind operates. The novel approach to teaching a…

  10. Engineering Certification Program Self-Study Course, Construction Inspection - Part II. Engineering Management [Series].

    ERIC Educational Resources Information Center

    Owsley, Fran, Ed.

    This book is a part of a self-study sequence in an engineering certification program. This volume concerns inspection and quality control of concrete structures. Sections titles are Inspection and Quality Control of Concrete; General Guides for Concrete Work; Concrete Floor and Slab Construction; Concrete Formwork; Correct and Incorrect Methods of…

  11. 25 CFR 900.111 - What activities of construction programs are contractible?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND...? The Secretary shall, upon the request of any Indian tribe or tribal organization authorized by tribal resolution, enter into a self-determination contract to plan, conduct, and administer construction programs...

  12. Environmental Assessment for the Construction and Operation of the Constellation Program A-3 Test Stand

    NASA Technical Reports Server (NTRS)

    Kennedy, Carolyn D.

    2007-01-01

    This document is an environmental assessment that examines the environmental impacts of a proposed plan to clear land and to construct a test stand for use in testing the J-2X rocket engine at simulated altitude conditions in support of NASA's Constellation Program.

  13. 78 FR 13646 - Applications for New Awards; Impact Aid Discretionary Construction Grant Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-28

    ... percent of its bond limit; or (iii) Is eligible to receive funds for the fiscal year for heavily impacted... Applications for New Awards; Impact Aid Discretionary Construction Grant Program AGENCY: Office of Elementary and Secondary Education, Department of Education. ACTION: Notice. Overview Information Impact Aid...

  14. Engineering Certification Program Self-Study Course, Construction Inspection - Part II. Engineering Management [Series].

    ERIC Educational Resources Information Center

    Owsley, Fran, Ed.

    This book is a part of a self-study sequence in an engineering certification program. This volume concerns inspection and quality control of concrete structures. Sections titles are Inspection and Quality Control of Concrete; General Guides for Concrete Work; Concrete Floor and Slab Construction; Concrete Formwork; Correct and Incorrect Methods of…

  15. Programming for the Internet and Experiential Learning: A New Approach Incorporating a Constructed World

    ERIC Educational Resources Information Center

    Taylor, Adam P. R.

    2007-01-01

    This paper reports on a novel approach taken by the author to the teaching of an Internet programming course targeted at final year diploma and second year degree students. The uniqueness of engineers and their identity is discussed, as is the self-constructed world and ways of knowing in which humankind operates. The novel approach to teaching a…

  16. The Laborers-AGC Construction Skills Training Program. Final Performance Report.

    ERIC Educational Resources Information Center

    Tippie, John L.; Rice, Eric

    Patterned after a previously successful Laborers-Associated General Contractors model named the Construction Skills Training Program, a demonstration project was implemented at five regional training centers. At least eight courses were created, combined, or revised. Four full-length audiovisual support pieces were completed. Three courses were…

  17. Constructing Adult Literacies at a Local Literacy Tutor-Training Program

    ERIC Educational Resources Information Center

    Roderick, Ryan

    2013-01-01

    This study investigates how literacy was constructed at an adult literacy organization's volunteer tutor-training program. By drawing on qualitative analysis of training texts used during training, such as training evaluations, and data gathered from interviews with experienced tutors, it is possible to identify the assumptions about literacy…

  18. 7 CFR 3015.85 - Outlay report and request for reimbursement for construction programs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... construction programs. 3015.85 Section 3015.85 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Financial Reporting Requirements § 3015.85 Outlay report and request for reimbursement for...

  19. 17 CFR 149.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Program accessibility: New construction and alterations. 149.151 Section 149.151 Commodity and Securities Exchanges COMMODITY FUTURES... usable by handicapped persons. The definitions, requirements, and standards of the Architectural...

  20. 17 CFR 149.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Program accessibility: New construction and alterations. 149.151 Section 149.151 Commodity and Securities Exchanges COMMODITY FUTURES... usable by handicapped persons. The definitions, requirements, and standards of the Architectural...

  1. An Interactive Computer Program to Construct Adaptive Landscapes and to Simulate the Changes Expected with Selection

    ERIC Educational Resources Information Center

    Hull, Peter

    1978-01-01

    Describes an interactive computer program which can be used by students to construct adaptive landscapes of two types as an illustration of the expected effects of selection. Simulates effects of selection on populations of this type and changes of gene frequency can be plotted on the same contour map. (Author/MA)

  2. 34 CFR 1200.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Program accessibility: New construction and alterations. 1200.151 Section 1200.151 Education Regulations of the Offices of the Department of Education (Continued) NATIONAL COUNCIL ON DISABILITY ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP...

  3. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Program accessibility: new construction and alterations. 1807.151 Section 1807.151 National Defense Other Regulations Relating to National Defense NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN...

  4. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Program accessibility: new construction and alterations. 1807.151 Section 1807.151 National Defense Other Regulations Relating to National Defense NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN...

  5. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Program accessibility: new construction and alterations. 1807.151 Section 1807.151 National Defense Other Regulations Relating to National Defense NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN...

  6. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Program accessibility: new construction and alterations. 1807.151 Section 1807.151 National Defense Other Regulations Relating to National Defense NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN...

  7. 32 CFR 1807.151 - Program accessibility: new construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Program accessibility: new construction and alterations. 1807.151 Section 1807.151 National Defense Other Regulations Relating to National Defense NATIONAL COUNTERINTELLIGENCE CENTER ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF DISABILITY IN...

  8. The Sexual Assault Teach In Program: Building Constructive Campus-Wide Discussions to Inspire Change

    ERIC Educational Resources Information Center

    Katz, Jennifer; DuBois, Melinda

    2013-01-01

    To begin to address the problem of campus sexual assault, we conducted a Teach In, an educational forum used to explore complex social problems. All students, faculty, and staff at our small liberal arts college were invited to participate. This paper summarizes our Teach In program, goals, and methods. By engaging in constructive, informed…

  9. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Defense Environmental... System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction contracts...

  10. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Defense Environmental... System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction contracts...

  11. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Defense Environmental... System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction...

  12. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Defense Environmental... System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction...

  13. 48 CFR 228.102-70 - Defense Environmental Restoration Program construction contracts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Defense Environmental... System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 228.102-70 Defense Environmental Restoration Program construction...

  14. 34 CFR 105.33 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Program accessibility: New construction and alterations. 105.33 Section 105.33 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN...

  15. Computer program offers new method for constructing periodic orbits in nonlinear dynamical systems

    NASA Technical Reports Server (NTRS)

    Bennett, A. G.; Hanafy, L. M.; Palmore, J. I.

    1968-01-01

    Computer program uses an iterative method to construct precisely periodic orbits which dynamically approximate solutions that converge to precise dynamical solutions in the limit of the sequence. The method used is a modification of the generalized Newton-Raphson algorithm used in analyzing two point boundary problems.

  16. Library Services and Construction Act (LSCA). South Carolina State-Administration Annual Program, 1992-1993.

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    Supporting documentation for the grant and use of Federal Library Services and Construction Act (LSCA) funds in South Carolina is presented in this annual program. Under Title I, Library Services, the bulk of the grant money is planned for the following projects: (1) general administration (Project I-A); (2) library interpretation (Project I-B);…

  17. 44 CFR 16.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Program accessibility: New construction and alterations. 16.151 Section 16.151 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY GENERAL ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS...

  18. 41 CFR 105-8.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Program accessibility: New construction and alterations. 105-8.151 Section 105-8.151 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

  19. The Sexual Assault Teach In Program: Building Constructive Campus-Wide Discussions to Inspire Change

    ERIC Educational Resources Information Center

    Katz, Jennifer; DuBois, Melinda

    2013-01-01

    To begin to address the problem of campus sexual assault, we conducted a Teach In, an educational forum used to explore complex social problems. All students, faculty, and staff at our small liberal arts college were invited to participate. This paper summarizes our Teach In program, goals, and methods. By engaging in constructive, informed…

  20. How Learners Perceive They Construct Knowledge as Participants in Outreach Programs

    ERIC Educational Resources Information Center

    Yelich Biniecki, Susan

    2010-01-01

    The purpose of this interpretive qualitative research study was to explore how adult learners perceive they construct knowledge in connection to their participation in educational outreach programs, encompassing a continuum of formal, non-formal, and informal learning experiences. The study context involved three world affairs outreach education…

  1. How Learners Perceive They Construct Knowledge as Participants in Outreach Programs

    ERIC Educational Resources Information Center

    Yelich Biniecki, Susan

    2010-01-01

    The purpose of this interpretive qualitative research study was to explore how adult learners perceive they construct knowledge in connection to their participation in educational outreach programs, encompassing a continuum of formal, non-formal, and informal learning experiences. The study context involved three world affairs outreach education…

  2. Breaking Ground: Rebuilding New Jersey's Urban Schools. The Abbott School Construction Program

    ERIC Educational Resources Information Center

    Ponessa, Joan

    2004-01-01

    This report presents a brief history of the Abbott School Construction Program, describes the implementation to date, lays out some current challenges, and outlines lessons learned from the process so far--what is known now about how such an initiative should be planned and carried out. The report is intended to illuminate the complex process of…

  3. 78 FR 25062 - Program for Construction, Renovation, Repair or Expansion of Public Schools Located on Military...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-29

    ... on Military Installations AGENCY: Office of Economic Adjustment (OEA), Department of Defense (DoD... program to construct, renovate, repair, or expand elementary and ] secondary public schools on military... Schools Located on Military Installations. Announcement Type: Federal Funding Opportunity. Catalog of...

  4. The Hazards of Training: Attrition and Retention in Construction Industry Apprenticeship Programs.

    ERIC Educational Resources Information Center

    Bilginsoy, Cihan

    2003-01-01

    Of 12,715 construction industry apprentices, 39% graduated, 47% canceled, and 14% were still enrolled. Completion was more likely in programs sponsored jointly by employers and unions. Women and ethnic/racial minorities had lower completion rates than men and whites. Duration of apprenticeship increased with the unemployment rate. (Contains 18…

  5. Constructing Adult Literacies at a Local Literacy Tutor-Training Program

    ERIC Educational Resources Information Center

    Roderick, Ryan

    2013-01-01

    This study investigates how literacy was constructed at an adult literacy organization's volunteer tutor-training program. By drawing on qualitative analysis of training texts used during training, such as training evaluations, and data gathered from interviews with experienced tutors, it is possible to identify the assumptions about literacy…

  6. THE CONSTRUCTION AND EVALUATION OF A SELF-INSTRUCTIONAL PROGRAM IN RUSSIAN.

    ERIC Educational Resources Information Center

    SALTZMAN, IRVING J.

    A SELF-INSTRUCTIONAL PROGRAMED COURSE IN RUSSIAN WAS CONSTRUCTED. FIFTEEN THOUSAND PRINTED FRAMES AND 306 TAPES WERE PREPARED FOR USE BY HIGH SCHOOL OR FIRST-SEMESTER COLLEGE STUDENTS. THE MATERIALS WERE USED TO (1) PROVIDE A RESEARCH TOOL FOR STUDYING SECOND LANGUAGE INSTRUCTION AND ACQUISITION AND (2) YIELD INFORMATIO ABOUT THE DEVELOPMENT OF…

  7. A Scientist or Salesman? Identity Construction through Referent Honorifics on a Japanese Shopping Channel Program

    ERIC Educational Resources Information Center

    Cook, Haruko Minegishi

    2013-01-01

    This paper explores how referent honorifics contribute to identity construction on a Japanese TV shopping channel program. Drawing on Ochs' twostep model of indexicality (1993, 1996) and Agah's proposal (1993) that honorifics are not directly linked to social status but index a "relative position within events of discursive interaction"…

  8. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a)(1), use the following clause: Balance of Payments Program...

  9. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a), use the following clause: Balance of Payments Program...

  10. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a)(1), use the following clause: Balance of Payments Program...

  11. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a)(1), use the following clause: Balance of Payments Program...

  12. 48 CFR 252.225-7044 - Balance of Payments Program-Construction Material.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Balance of Payments... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7044 Balance of Payments Program—Construction Material. As prescribed in 225.7503(a)(1), use the following clause: Balance of Payments Program...

  13. A Scientist or Salesman? Identity Construction through Referent Honorifics on a Japanese Shopping Channel Program

    ERIC Educational Resources Information Center

    Cook, Haruko Minegishi

    2013-01-01

    This paper explores how referent honorifics contribute to identity construction on a Japanese TV shopping channel program. Drawing on Ochs' twostep model of indexicality (1993, 1996) and Agah's proposal (1993) that honorifics are not directly linked to social status but index a "relative position within events of discursive interaction"…

  14. MAPAG: a computer program to construct 2- and 3-dimensional antigenic maps.

    PubMed

    Aguilar, R C; Retegui, L A; Roguin, L P

    1994-01-01

    The contact area between an antibody (Ab) and the antigen (Ag) is called antigenic determinant or epitope. The first step in the characterization of an Ag by using monoclonal antibodies (MAb) is to map the relative distribution of the corresponding epitopes on the Ag surface. The computer program MAPAG has been devised to automatically construct antigenic maps. MAPAG is fed with a binary matrix of experimental data indicating the ability of paired MAb to bind or not simultaneously to the Ag. The program is interactive menu-driven and allows the user an easy data handling. MAPAG utilizes iterative processes to construct and to adjust the final map, which is graphically shown as a 2- or a 3-dimensional model. Additionally, the antigenic map obtained can be optionally modified by the user or readjusted by the program. The suitability of MAPAG was illustrated by running experimental data from literature and comparing antigenic maps constructed by the program with those elaborated by the investigators without the assistance of a computer. Furthermore, since some MAb could present negative allosteric effects leading to misinterpretation of data, MAPAG has been provided with an approximate reasoning module to solve such anomalous situations. Results indicated that the program can be successfully employed as a simple, fast and reliable antigenic model-builder.

  15. THE ENZYMATIC NATURE OF C'1r

    PubMed Central

    Naff, George B.; Ratnoff, Oscar D.

    1968-01-01

    Human C'1, a macromolecular complex composed of three subunits, is the zymogen for at least two distinct enzymes. Preparations of one subunit, C'1r, functioned as a protease which converted another subunit, C'1s, to C'1 esterase. The conversion of C'1s to C'1 esterase by C'1r was blocked by Liquoid, phenyl methylsulfonyl fluoride, and calcium ions, but not by soybean trypsin inhibitor, hirudin, or heparin. Preparations of C'1r also possessed two additional functions, i.e., the ability to hydrolyze certain synthetic amino acid esters and to participate in immune hemolysis. Evidence was presented which indicates that these three functions are properties of a single entity, C'1r, but not of the same portion of its molecular structure. These observations suggest that C'1r has at least two active sites, one for its reaction with C'1q, an additional subunit of C'1, and one for its reaction with C'1s; together, the three subcomponents, C'1q, C'1r, and C'1s, form a single functional unit, the first component of complement. PMID:5675434

  16. Worksite wellness program for respiratory disease prevention in heavy-construction workers.

    PubMed

    Hnizdo, Eva; Berry, Angela; Hakobyan, Artak; Beeckman-Wagner, Lu-Ann; Catlett, Larry

    2011-03-01

    To describe a respiratory disease prevention program in a US heavy-construction company. The program uses periodic spirometry and questionnaires and is integrated into a worksite wellness program involving individualized intervention. Spirometry Longitudinal Data Analysis (SPIROLA) technology is used to assist the physician with (i) management and evaluation of longitudinal spirometry and questionnaire data; (ii) designing, recoding, and implementing intervention; and (iii) evaluation of impact of the intervention. Preintervention data provide benchmark results. Preintervention results on 1224 workers with 5 or more years of follow-up showed that the mean rate of FEV1 decline was 47 mL/year. Age-stratified prevalence of moderate airflow obstruction was higher than that for the US population. Preintervention results indicate the need for respiratory disease prevention in this construction workforce and provide a benchmark for future evaluation of the intervention.

  17. Construction

    DTIC Science & Technology

    2003-01-01

    hot water, appliances, lightening and misc.66 Average and efficient energy costs were determined for each base. The collection of average and...data and the appropriate regional median condominium87 and apartment O&M costs . For new housing projects the energy efficient utility costs were used...supply of domestic skilled laborers and the increasing cost of insurance. The construction industry has always contracted and expanded based

  18. Residential building code compliance: Implications for evaluating the performance of utility residential new construction programs

    SciTech Connect

    Vine, E.

    1996-05-01

    Knowing how well builders comply with (or exceed) energy-related building codes is critical for completing a sound evaluation of utility residential new construction programs and for determining the actual cost-effectiveness of these programs. Obtaining credit from utility regulators for additional energy savings from code compliance in participant houses as a result of the utility program is one of the key options available for utilities for improving the cost-effectiveness of these programs. In this paper, the authors examine residential building energy code compliance and specific code violations in three states (California, Oregon and Washington). They then compare residential building energy code compliance for program participants and nonparticipants as well as estimates of the energy savings impacts from noncompliance. The authors also point out some of the methodological limitations of these studies which limit the ability to generalize from these studies.

  19. Military construction program economic analysis manual: Text and appendixes: Hazardous Waste Remedial Actions Program. [Contains glossary

    SciTech Connect

    Not Available

    1987-12-01

    This manual enables the US Air Force to comprehensively and systematically analyze alternative approaches to meeting its military construction requirements. The manual includes step-by-step procedures for completing economic analyses for military construction projects, beginning with determining if an analysis is necessary. Instructions and a checklist of the tasks involved for each step are provided; and examples of calculations and illustrations of completed forms are included. The manual explains the major tasks of an economic analysis, including identifying the problem, selecting realistic alternatives for solving it, formulating appropriate assumptions, determining the costs and benefits of the alternatives, comparing the alternatives, testing the sensitivity of major uncertainties, and ranking the alternatives. Appendixes are included that contain data, indexes, and worksheets to aid in performing the economic analyses. For reference, Volume 2 contains sample economic analyses that illustrate how each form is filled out and that include a complete example of the documentation required. 6 figs., 12 tabs.

  20. Construction

    DTIC Science & Technology

    2001-01-01

    equipment. Engineering , building, and project owner/ developers include industrial manufacturers, public works departments, public and private...Honolulu, Hawaii: U.S. Pacific Command, Headquarters Building Naval Facilities Engineer Command - Ford Island Development Program, Hawaii 2... industry where reputation means everything and industry -leading firms invest significant resources in business development and work hard to ensure

  1. Injury rates, severity, and drug testing programs in small construction companies.

    PubMed

    Schofield, Katherine Elizabeth; Alexander, Bruce H; Gerberich, Susan Goodwin; Ryan, Andrew D

    2013-02-01

    Construction work is hazardous and workers consistently rank in the top of all occupations and industries for illicit drug and heavy alcohol use. Drug-testing programs were classified into three categories: no program, pre-employment/post-accident, and pre-employment/post-accident/random/suspicion. We analyzed workers' compensation claims from 1,360 construction companies over a six-year period to assess the possible association of testing program with injury rate. Compared to no program, results respectively were RR=0.85 (CI=0.72-1.0) and RR=0.97 (CI=0.86-1.10) for all injuries, and RR=0.78 (CI=0.60-1.03) and RR=1.01 (CI=0.86-1.19) for lost-time injuries. Variability of results was exhibited across trade and union status, among other categories. Drug-testing programs may be associated with lower, non-significant, injury rates in this population. Drug-testing programs may be associated with lower injury rates, but care should be exercised to ensure accurate injury reporting, characterize underlying safety practices of a company, and to determine quality and consistency of testing. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Department of the Navy FY 1985 Military Construction & Family Housing Program.

    DTIC Science & Technology

    1984-02-01

    V-Y- FY 19 8SMILITARY CONSTRUCTION PROJEC’, DATA * 3 ISTALLATION AD LOCATION 4. PROJECT TITLE PERSONNEL SUPPORT ACTIVITY,O DAY AND PERSON EL SUPPORT...TITLE SCOPE ’SOW’ START COw 550.10 Medical/Dental Clinic 7,960 SF 1,410 8-83 9-84 (MWTC Bridgeport) TOTAL 1,410 * .ŝ. Future Projects: a. included in...MILITARY CONSTRUCTION PROGRAM NAVY 3. ISTALLATION AND LOCATION 4. COMMAND I.AA ONS, R. COST INDEx NAVAL ACTIVITIES, COMMANDER IN CHIEF, LONDON, UNITED

  3. Cone Quasi-Concave Multi-Objective Programming Theory and Dominance Cone Constructions.

    DTIC Science & Technology

    1988-08-01

    4 Cone Quasi-Concave Multi-Objective Prog ramm in(I Theory and Dominance Cone Constructions by A. Chames Z. M. Huang J. J. Rousseau 0. B. Sun 0. L...Report 606 Cone Quasi-Concave Multi-Objective Programming: Theory and Dominance Cone Constructions by A. Chames Z. M. Huang J. J. Rousseau D. B. Sun...permitted for any purpose of the U.S. Govemement. Tr% C CENTER FOR CYBERNETIC STUDIES cV- A. Chames , Director V 3 D 1 College of Business Administration

  4. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... an AFA? 1000.249 Section 1000.249 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program in an AFA? The Secretary has the following role regarding a construction program contained in an AFA: (a) Except as provided in § 1000.256, the Secretary may review and approve planning...

  5. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  6. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... an AFA? 1000.249 Section 1000.249 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program in an AFA? The Secretary has the following role regarding a construction program contained in an AFA: (a) Except as provided in § 1000.256, the Secretary may review and approve planning...

  7. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  8. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... an AFA? 1000.249 Section 1000.249 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program in an AFA? The Secretary has the following role regarding a construction program contained in an AFA: (a) Except as provided in § 1000.256, the Secretary may review and approve planning...

  9. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... an AFA? 1000.249 Section 1000.249 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program in an AFA? The Secretary has the following role regarding a construction program contained in an AFA: (a) Except as provided in § 1000.256, the Secretary may review and approve planning...

  10. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  11. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  12. 25 CFR 1000.248 - What is the Tribe's/Consortium's role in a construction program included in an AFA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... program included in an AFA? 1000.248 Section 1000.248 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN.../Consortium's role in a construction program included in an AFA? The Tribe/Consortium has the following role regarding a construction portion of an AFA: (a) Under the Act, the Indian Tribe/Consortium must...

  13. 25 CFR 1000.249 - What is the Secretary's role in a construction program in an AFA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... an AFA? 1000.249 Section 1000.249 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program in an AFA? The Secretary has the following role regarding a construction program contained in an AFA: (a) Except as provided in § 1000.256, the Secretary may review and approve planning...

  14. 25 CFR 170.404 - What happens when a tribe uses its IRR Program construction funds for transportation planning?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What happens when a tribe uses its IRR Program construction funds for transportation planning? 170.404 Section 170.404 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER INDIAN RESERVATION ROADS PROGRAM Planning, Design, and Construction...

  15. A constructive Indian country response to the evidence-based program mandate.

    PubMed

    Walker, R Dale; Bigelow, Douglas A

    2011-01-01

    Over the last 20 years governmental mandates for preferentially funding evidence-based "model" practices and programs has become doctrine in some legislative bodies, federal agencies, and state agencies. It was assumed that what works in small sample, controlled settings would work in all community settings, substantially improving safety, effectiveness, and value-for-money. The evidence-based "model" programs mandate has imposed immutable "core components," fidelity testing, alien programming and program developers, loss of familiar programs, and resource capacity requirements upon tribes, while infringing upon their tribal sovereignty and consultation rights. Tribal response in one state (Oregon) went through three phases: shock and rejection; proposing an alternative approach using criteria of cultural appropriateness, aspiring to evaluability; and adopting logic modeling. The state heard and accepted the argument that the tribal way of knowing is different and valid. Currently, a state-authorized tribal logic model and a review panel process are used to approve tribal best practices for state funding. This constructive response to the evidence-based program mandate elevates tribal practices in the funding and regulatory world, facilitates continuing quality improvement and evaluation, while ensuring that practices and programs remain based on local community context and culture. This article provides details of a model that could well serve tribes facing evidence-based model program mandates throughout the country.

  16. Concept document of the repository-based software engineering program: A constructive appraisal

    NASA Technical Reports Server (NTRS)

    1992-01-01

    A constructive appraisal of the Concept Document of the Repository-Based Software Engineering Program is provided. The Concept Document is designed to provide an overview of the Repository-Based Software Engineering (RBSE) Program. The Document should be brief and provide the context for reading subsequent requirements and product specifications. That is, all requirements to be developed should be traceable to the Concept Document. Applied Expertise's analysis of the Document was directed toward assuring that: (1) the Executive Summary provides a clear, concise, and comprehensive overview of the Concept (rewrite as necessary); (2) the sections of the Document make best use of the NASA 'Data Item Description' for concept documents; (3) the information contained in the Document provides a foundation for subsequent requirements; and (4) the document adequately: identifies the problem being addressed; articulates RBSE's specific role; specifies the unique aspects of the program; and identifies the nature and extent of the program's users.

  17. Power Grid Construction Project Portfolio Optimization Based on Bi-level programming model

    NASA Astrophysics Data System (ADS)

    Zhao, Erdong; Li, Shangqi

    2017-08-01

    As the main body of power grid operation, county-level power supply enterprises undertake an important emission to guarantee the security of power grid operation and safeguard social power using order. The optimization of grid construction projects has been a key issue of power supply capacity and service level of grid enterprises. According to the actual situation of power grid construction project optimization of county-level power enterprises, on the basis of qualitative analysis of the projects, this paper builds a Bi-level programming model based on quantitative analysis. The upper layer of the model is the target restriction of the optimal portfolio; the lower layer of the model is enterprises’ financial restrictions on the size of the enterprise project portfolio. Finally, using a real example to illustrate operation proceeding and the optimization result of the model. Through qualitative analysis and quantitative analysis, the bi-level programming model improves the accuracy and normative standardization of power grid enterprises projects.

  18. Predators of knowledge construction: Interpreting students' metacognition in an amusement park physics program

    NASA Astrophysics Data System (ADS)

    Anderson, David; Nashon, Samson

    2007-03-01

    It is recognized widely that learning is a dynamic and idiosyncratic process of construction and reconstruction of concepts in response to new experiences. It is influenced by the learner's prior knowledge, motivation, and sociocultural context. This study investigated how year 11 and 12 physics students' metacognition influences the development of their conceptual understandings of kinematics. An interpretive case study approach was used to investigate students working in collaborative groups in the context of an amusement park physics program. The metacognitive character of individual learners was demonstrated to have a strong influence on their conceptual development. Moreover, the metacognitive character of individuals within the small group contexts investigated was a key factor influencing the groups' collective knowledge development. A coyote-rabbit metaphor was developed to interpret the resilience and weaknesses of individual and group knowledge construction processes, and elucidates new theoretical understandings regarding metacognition and its influence on knowledge construction.

  19. Determining Recoupable Funds Using the Military Construction, Army Mobilization Program (MOBPRO).

    DTIC Science & Technology

    1992-07-01

    Construction, Army (MCA) programming is a complex, dynamic process operating in an environment that involves many functional managers. At all levels of the MCA...preferred methods for determining Government liability in convenience terminations, which involve interpreting fixed-price contracts as hybrid cost...the contract, initiate all actions necessary to close out the contract, and submit a settlement proposal. The settlement proposal informs the

  20. Prevention of falls in the construction industry: evidence for program effectiveness.

    PubMed

    Rivara, F P; Thompson, D C

    2000-05-01

    The objective of this study was to review the evidence for the effectiveness of different strategies to prevent falls from heights in the construction industry. We used the Cochrane Collaboration search strategy to search the following electronic databases: MEDLINE, EMBASE, NIOSHTIC, PsycINFO and Dissertation Abstracts. The reference lists from each potentially eligible study were checked, and knowledgeable people in the field were contacted for additional leads to published reports. Studies were included if they (1) examined the effectiveness of an intervention to decrease falls from heights to construction workers, (2) included data on one of the outcomes of interest, and (3) included a comparison group. We identified only three studies for review. An ecologic study found some evidence that regulations with enforcement may decrease falls in construction industry. Two studies on educational efforts suggested that educational programs may decrease falls but methodologic limitations restricted the conclusions that could be drawn. There are few data to support the effectiveness of current programs to decrease fall-related injuries in the construction industry. Rigorous evaluation of these interventions is indicated.

  1. Backstepping-Based Lyapunov Function Construction Using Approximate Dynamic Programming and Sum of Square Techniques.

    PubMed

    Wang, Zheng; Liu, Xiaoping; Liu, Kefu; Li, Shuai; Wang, Huanqing

    2016-06-20

    In this paper, backstepping for a class of block strict-feedback nonlinear systems is considered. Since the input function could be zero for each backstepping step, the backstepping technique cannot be applied directly. Based on the assumption that nonlinear systems are polynomials, for each backstepping step, Lypunov function can be constructed in a polynomial form by sum of square (SOS) technique. The virtual control can be obtained by the Sontag feedback formula, which is equivalent to an optimal control-the solution of a Hamilton-Jacobi-Bellman equation. Thus, approximate dynamic programming (ADP) could be used to estimate value functions (Lyapunov functions) instead of SOS. Through backstepping technique, the control Lyapunov function (CLF) of the full system is constructed finally making use of the strict-feedback structure and a stabilizable controller can be obtained through the constructed CLF. The contributions of the proposed method are twofold. On one hand, introducing ADP into backstepping can broaden the application of the backstepping technique. A class of block strict-feedback systems can be dealt by the proposed method and the requirement of nonzero input function for each backstepping step can be relaxed. On the other hand, backstepping with surface dynamic control actually reduces the computation complexity of ADP through constructing one part of the CLF by solving semidefinite programming using SOS. Simulation results verify contributions of the proposed method.

  2. Curtiss XSO3C-1 Seagull

    NASA Technical Reports Server (NTRS)

    1940-01-01

    Curtiss XSO3C-1 Seagull: Although drag reduction was very important to radial engined aircraft, it was no less important to aircraft such as this inline Ranger powered Curtiss XSO3C-1 Seagull. Here the Seagull is shown in the 30 x 60 Full Scale Tunnel in October of 1940. The XSO3C-1 was also undergoing study to improve engine cooling. Published in Aircraft; FST; Curtiss XSO3C-1 Seagull; Full Scale Tunnel; Nicklas

  3. Correlation between safety climate and contractor safety assessment programs in construction

    PubMed Central

    Sparer, EH1; Murphy, LA; Taylor, KM; Dennerlein, Jt

    2015-01-01

    Background Contractor safety assessment programs (CSAPs) measure safety performance by integrating multiple data sources together; however, the relationship between these measures of safety performance and safety climate within the construction industry is unknown. Methods 401 construction workers employed by 68 companies on 26 sites and 11 safety managers employed by 11 companies completed brief surveys containing a nine-item safety climate scale developed for the construction industry. CSAP scores from ConstructSecure, Inc., an online CSAP database, classified these 68 companies as high or low scorers, with the median score of the sample population as the threshold. Spearman rank correlations evaluated the association between the CSAP score and the safety climate score at the individual level, as well as with various grouping methodologies. In addition, Spearman correlations evaluated the comparison between manager-assessed safety climate and worker-assessed safety climate. Results There were no statistically significant differences between safety climate scores reported by workers in the high and low CSAP groups. There were, at best, weak correlations between workers’ safety climate scores and the company CSAP scores, with marginal statistical significance with two groupings of the data. There were also no significant differences between the manager-assessed safety climate and the worker-assessed safety climate scores. Conclusions A CSAP safety performance score does not appear to capture safety climate, as measured in this study. The nature of safety climate in construction is complex, which may be reflective of the challenges in measuring safety climate within this industry. PMID:24038403

  4. 29 CFR 2575.502c-1 - Adjusted civil penalty under section 502(c)(1).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Adjusted civil penalty under section 502(c)(1). 2575.502c-1 Section 2575.502c-1 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY... ERISA Title I § 2575.502c-1 Adjusted civil penalty under section 502(c)(1). In accordance with...

  5. Determining Safety Inspection Thresholds for Employee Incentives Programs on Construction Sites

    PubMed Central

    Sparer, Emily; Dennerlein, Jack

    2017-01-01

    The goal of this project was to evaluate approaches of determining the numerical value of a safety inspection score that would activate a reward in an employee safety incentive program. Safety inspections are a reflection of the physical working conditions at a construction site and provide a safety score that can be used in incentive programs to reward workers. Yet it is unclear what level of safety should be used when implementing this kind of program. This study explored five ways of grouping safety inspection data collected during 19 months at Harvard University-owned construction projects. Each approach grouped the data by one of the following: owner, general contractor, project, trade, or subcontractor. The median value for each grouping provided the threshold score. These five approaches were then applied to data from a completed project in order to calculate the frequency and distribution of rewards in a monthly safety incentive program. The application of each approach was evaluated qualitatively for consistency, competitiveness, attainability, and fairness. The owner-specific approach resulted in a threshold score of 96.3% and met all of the qualitative evaluation goals. It had the most competitive reward distribution (only 1/3 of the project duration) yet it was also attainable. By treating all workers equally and maintaining the same value throughout the project duration, this approach was fair and consistent. The owner-based approach for threshold determination can be used by owners or general contractors when creating leading indicator incentives programs and by researchers in future studies on incentive program effectiveness. PMID:28638178

  6. Determining Safety Inspection Thresholds for Employee Incentives Programs on Construction Sites.

    PubMed

    Sparer, Emily; Dennerlein, Jack

    2013-01-01

    The goal of this project was to evaluate approaches of determining the numerical value of a safety inspection score that would activate a reward in an employee safety incentive program. Safety inspections are a reflection of the physical working conditions at a construction site and provide a safety score that can be used in incentive programs to reward workers. Yet it is unclear what level of safety should be used when implementing this kind of program. This study explored five ways of grouping safety inspection data collected during 19 months at Harvard University-owned construction projects. Each approach grouped the data by one of the following: owner, general contractor, project, trade, or subcontractor. The median value for each grouping provided the threshold score. These five approaches were then applied to data from a completed project in order to calculate the frequency and distribution of rewards in a monthly safety incentive program. The application of each approach was evaluated qualitatively for consistency, competitiveness, attainability, and fairness. The owner-specific approach resulted in a threshold score of 96.3% and met all of the qualitative evaluation goals. It had the most competitive reward distribution (only 1/3 of the project duration) yet it was also attainable. By treating all workers equally and maintaining the same value throughout the project duration, this approach was fair and consistent. The owner-based approach for threshold determination can be used by owners or general contractors when creating leading indicator incentives programs and by researchers in future studies on incentive program effectiveness.

  7. Refinable C(1) spline elements for irregular quad layout.

    PubMed

    Nguyen, Thien; Peters, Jörg

    2016-03-01

    Building on a result of U. Reif on removable singularities, we construct C(1) bi-3 splines that may include irregular points where less or more than four tensor-product patches meet. The resulting space complements PHT splines, is refinable and the refined spaces are nested, preserving for example surfaces constructed from the splines. As in the regular case, each quadrilateral has four degrees of freedom, each associated with one spline and the splines are linearly independent. Examples of use for surface construction and isogeometric analysis are provided.

  8. Construction safety program for the National Ignition Facility, July 30, 1999

    SciTech Connect

    Benjamin, D W

    1999-07-30

    The Construction Safety Program (CSP) for NIF sets forth the responsibilities, guidelines, rules, policies and regulations for all workers involved in the construction, special equipment installation, acceptance testing, and start-up of NIF at LLNL during the construction period of NIF. During this period, all workers are required to implement measures to create a universal awareness which promotes safe practice at the work site, and which will achieve NIF's management objectives in preventing accidents and illnesses. Construction safety for NIF is predicated on everyone performing their jobs in a manner that prevents job-related disabling injuries and illnesses. Integrated Safety Management (ISM) is practiced in the execution of all activities associated with the NIF Project. The seven Principles of ISM are: (1) Line management is responsible for safety. (2) Clear roles and responsibilities are established and maintained. (3) Personnel possess competence commensurate with responsibilities. (4) Resource allocations are balanced, making ES and H a priority in project planning and execution. (5) Safety requirements are identified and implemented. (6) Hazard controls are tailored to the project work. (7) Operations are authorized before work begins.

  9. Social marketing to plan a fall prevention program for Latino construction workers.

    PubMed

    Menzel, Nancy N; Shrestha, Pramen P

    2012-08-01

    Latino construction workers experience disparities in occupational death and injury rates. The Occupational Safety and Health Administration funded a fall prevention training program at the University of Nevada, Las Vegas in response to sharp increases in fall-related accidents from 2005 to 2007. The grant's purpose was to improve fall protection for construction workers, with a focus on Latinos. This study assessed the effectiveness of social marketing for increasing fall prevention behaviors. A multi-disciplinary team used a social marketing approach to plan the program. We conducted same day class evaluations and follow-up interviews 8 weeks later. The classes met trainee needs as evidenced by class evaluations and increased safety behaviors. However, Spanish-speaking Latinos did not attend in the same proportion as their representation in the Las Vegas population. A social marketing approach to planning was helpful to customize the training to Latino worker needs. However, due to the limitations of behavior change strategies, future programs should target employers and their obligation to provide safer workplaces. Copyright © 2012 Wiley Periodicals, Inc.

  10. Assessing the cost of a cardiology residency program with a cost construction model.

    PubMed

    Franzini, L; Chen, S C; McGhie, A I; Low, M D

    1999-09-01

    Although the total costs of graduate medical education are difficult to quantify, this information is of great importance in planning over the next decade. A cost construction model was used to quantify the costs of teaching faculty, cardiology fellows' salaries and benefits, overhead (physical plant, equipment, and support staff), and other costs associated with the cardiology residency program at the University of Texas-Houston during the 1996 to 1997 academic year. Surveys of cardiology faculty and fellows, checked by the program director, were conducted to determine the time spent in teaching activities; access to institutional and departmental financial records was obtained to quantify associated costs. The model was then developed and examined for a range of assumptions concerning cardiology fellows' productivity, replacement costs, and the cost allocation of activities jointly producing clinical care and education. The instructional cost of training (cost of didactic, direct clinical supervision, preparation for teaching, and teaching-related administration, plus the support of the teaching program) was estimated at $73,939 per cardiology fellow per year. This cost was less than the estimated replacement value of the teaching and clinical services provided by cardiology fellows, $100,937 per cardiology fellow per year. Sensitivity analysis, with different assumptions on cardiology fellows' productivity and replacement costs, varied the cost estimates but generally represented the cardiology residency program as an asset. Cost construction models can be used as a tool to estimate variations in resource requirements resulting from changes in curriculum or educators' costs. In this residency, the value of the teaching and clinical services provided by cardiology fellows exceeded the cost of the resources used in the educational program.

  11. Northwest Energy Efficient Manufactured Housing Program: High Performance Manufactured Home Prototyping and Construction Development

    SciTech Connect

    Hewes, Tom; Peeks, Brady

    2013-11-01

    The Building America Partnership for Improved Residential Construction, the Bonneville Power Administration (BPA), and Northwest Energy Works (NEW), the current Northwest Energy Efficient Manufactured Housing Program (NEEM) administrator, have been collaborating to conduct research on new specifications that would improve on the energy requirements of a NEEM home. In its role as administrator, NEW administers the technical specs, performs research and engineering analysis, implements ongoing construction quality management procedures, and maintains a central database with home tracking. This project prototyped and assessed the performances of cost-effective high performance building assemblies and mechanical systems that are not commonly deployed in the manufacturing setting. The package of measures is able to reduce energy used for space conditioning, water heating and lighting by 50 percent over typical manufactured homes produced in the northwest.

  12. Northwest Energy Efficient Manufactured Housing Program: High Performance Manufactured Home Prototyping and Construction Development

    SciTech Connect

    Hewes, Tom; Peeks, Brady

    2013-11-01

    The Building America Partnership for Improved Residential Construction, the Bonneville Power Administration (BPA), and Northwest Energy Works (NEW), the current Northwest Energy Efficient Manufactured Housing Program (NEEM) administrator, have been collaborating to conduct research on new specifications that would improve on the energy requirements of a NEEM home. In its role as administrator, NEW administers the technical specs, performs research and engineering analysis, implements ongoing construction quality management procedures, and maintains a central database with home tracking. This project prototyped and assessed the performances of cost-effective high performance building assemblies and mechanical systems that are not commonly deployed in the manufacturing setting. The package of measures is able to reduce energy used for space conditioning, water heating and lighting by 50% over typical manufactured homes produced in the northwest.

  13. A cost-construction model to assess the total cost of an anesthesiology residency program.

    PubMed

    Franzini, L; Berry, J M

    1999-01-01

    Although the total costs of graduate medical education are difficult to quantify, this information may be of great importance for health policy and planning over the next decade. This study describes the total costs associated with the residency program at the University of Texas--Houston Department of Anesthesiology during the 1996-1997 academic year. The authors used cost-construction methodology, which computes the cost of teaching from information on program description, resident enrollment, faculty and resident salaries and benefits, and overhead. Surveys of faculty and residents were conducted to determine the time spent in teaching activities; access to institutional and departmental financial records was obtained to quantify associated costs. The model was then developed and examined for a range of assumptions concerning resident productivity, replacement costs, and the cost allocation of activities jointly producing clinical care and education. The cost of resident training (cost of didactic teaching, direct clinical supervision, teaching-related preparation and administration, plus the support of the teaching program) was estimated at $75,070 per resident per year. This cost was less than the estimated replacement value of the teaching and clinical services provided by residents, $103,436 per resident per year. Sensitivity analysis, with different assumptions regarding resident replacement cost and reimbursement rates, varied the cost estimates but generally identified the anesthesiology residency program as a financial asset. In most scenarios, the value of the teaching and clinical services provided by residents exceeded the cost of the resources used in the educational program.

  14. Alcohol binding in the C1 (C1A + C1B) domain of protein kinase C epsilon

    PubMed Central

    Pany, Satyabrata; Das, Joydip

    2015-01-01

    Background Alcohol regulates the expression and function of protein kinase C epsilon (PKCε). In a previous study we identified an alcohol binding site in the C1B, one of the twin C1 subdomains of PKCε. Methods In this study, we investigated alcohol binding in the entire C1 domain (combined C1A and C1B) of PKCε. Fluorescent phorbol ester, SAPD and fluorescent diacylglycerol (DAG) analog, dansyl-DAG were used to study the effect of ethanol, butanol, and octanol on the ligand binding using fluorescence resonance energy transfer (FRET). To identify alcohol binding site(s), PKCεC1 was photolabeled with 3-azibutanol and 3-azioctanol, and analyzed by mass spectrometry. The effects of alcohols and the azialcohols on PKCε were studied in NG108-15 cells. Results In the presence of alcohol, SAPD and dansyl-DAG showed different extent of FRET, indicating differential effects of alcohol on the C1A and C1B subdomains. Effects of alcohols and azialcohols on PKCε in NG108-15 cells were comparable. Azialcohols labeled Tyr-176 of C1A and Tyr-250 of C1B. Inspection of the model structure of PKCεC1 reveals that these residues are 40 Å apart from each other indicating that these residues form two different alcohol binding sites. Conclusions The present results provide evidence for the presence of multiple alcohol-binding sites on PKCε and underscore the importance of targeting this PKC isoform in developing alcohol antagonists. PMID:26210390

  15. C1 inhibitor: quantification and purification.

    PubMed

    Varga, Lilian; Dobó, József

    2014-01-01

    C1 inhibitor is a multipotent serpin capable of inhibiting the classical and the lectin pathways of complement, the fibrinolytic system, and contact/kinin system of coagulation. Deficiency of C1 inhibitor manifest as hereditary angioedema (HAE), an autosomal dominant hereditary disease. Measuring the C1 inhibitor level is of vital importance for the diagnosis of HAE and also for monitoring patients receiving C1 inhibitor for therapy. Determination of the antigenic C1 inhibitor level by the radial immunodiffusion (RID) technique is described in detail in this chapter. The presented purification method of plasma C1 inhibitor is primarily based on its high carbohydrate content and its affinity to the lectin jacalin.

  16. Correlation between safety climate and contractor safety assessment programs in construction.

    PubMed

    Sparer, Emily H; Murphy, Lauren A; Taylor, Kathryn M; Dennerlein, Jack T

    2013-12-01

    Contractor safety assessment programs (CSAPs) measure safety performance by integrating multiple data sources together; however, the relationship between these measures of safety performance and safety climate within the construction industry is unknown. Four hundred and one construction workers employed by 68 companies on 26 sites and 11 safety managers employed by 11 companies completed brief surveys containing a nine-item safety climate scale developed for the construction industry. CSAP scores from ConstructSecure, Inc., an online CSAP database, classified these 68 companies as high or low scorers, with the median score of the sample population as the threshold. Spearman rank correlations evaluated the association between the CSAP score and the safety climate score at the individual level, as well as with various grouping methodologies. In addition, Spearman correlations evaluated the comparison between manager-assessed safety climate and worker-assessed safety climate. There were no statistically significant differences between safety climate scores reported by workers in the high and low CSAP groups. There were, at best, weak correlations between workers' safety climate scores and the company CSAP scores, with marginal statistical significance with two groupings of the data. There were also no significant differences between the manager-assessed safety climate and the worker-assessed safety climate scores. A CSAP safety performance score does not appear to capture safety climate, as measured in this study. The nature of safety climate in construction is complex, which may be reflective of the challenges in measuring safety climate within this industry. Am. J. Ind. Med. 56:1463-1472, 2013. © 2013 Wiley Periodicals, Inc. © 2013 Wiley Periodicals, Inc.

  17. EPA construction grants: Information on the Milwaukee Area Sewerage System Improvement Program

    SciTech Connect

    Not Available

    1986-01-01

    The Milwaukee Sewerage Water Pollution Abatement Program was initiated in response to federal and state court lawsuits to halt Lake Michigan's pollution. It is about $360 million under budget and on schedule with a 1996 target completion date. GAO found that the district meets the federal criteria for an eligible grantee; federal and Wisconsin regulations permit architect and engineering contracts to be competitively negotiated and do not require advertised competitive bidding; the job site rule, which limits allowable overhead billings, was not applied because it was determined that the operation of the prime contractor responsible for managing the program and its technical integrity did not constitute a job site; no federal funds have been involved in the disposition of rock from the north shore project site; and the total estimated architect and engineering costs $344.7 million represent about 28 percent of total estimated construction costs.

  18. Relating Women's Experience and Skills to Competencies Required in Selected Occupations and Vocational Education Programs. Project Report, Task C1, Revised Competency Analysis: Credentialing Women's Life Experiences (Project ACCESS).

    ERIC Educational Resources Information Center

    Ekstrom, Ruth B.; And Others

    Competency scales were developed for 10 direct-entry occupations and 10 vocational education programs as part of Project ACCESS, a project to assess women's life experience learning for entrance into employment and for advanced placement in vocational education programs. Development of the occupational scales involved employer interviews, followed…

  19. 25 CFR 1000.242 - What provisions relating to a construction program may be included in an AFA?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... included in an AFA? 1000.242 Section 1000.242 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program may be included in an AFA? The Secretary and the Tribe/Consortium may negotiate to apply... to a construction part of an AFA. Absent a negotiated agreement, such provisions and...

  20. 25 CFR 1000.242 - What provisions relating to a construction program may be included in an AFA?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... included in an AFA? 1000.242 Section 1000.242 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program may be included in an AFA? The Secretary and the Tribe/Consortium may negotiate to apply... to a construction part of an AFA. Absent a negotiated agreement, such provisions and...

  1. 25 CFR 1000.242 - What provisions relating to a construction program may be included in an AFA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... included in an AFA? 1000.242 Section 1000.242 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program may be included in an AFA? The Secretary and the Tribe/Consortium may negotiate to apply... to a construction part of an AFA. Absent a negotiated agreement, such provisions and...

  2. 25 CFR 1000.242 - What provisions relating to a construction program may be included in an AFA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... included in an AFA? 1000.242 Section 1000.242 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program may be included in an AFA? The Secretary and the Tribe/Consortium may negotiate to apply... to a construction part of an AFA. Absent a negotiated agreement, such provisions and...

  3. 25 CFR 1000.242 - What provisions relating to a construction program may be included in an AFA?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... included in an AFA? 1000.242 Section 1000.242 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... construction program may be included in an AFA? The Secretary and the Tribe/Consortium may negotiate to apply... to a construction part of an AFA. Absent a negotiated agreement, such provisions and...

  4. Employers' Perception of Graduates with Entry-Level Technical Skills from Construction Industry Programs in Ghana and Nigeria

    ERIC Educational Resources Information Center

    Acheampong, Philip

    2013-01-01

    The purpose of this comparative study was to identify the technical skills and abilities needed by prospective employees of construction industries in Ghana and Nigeria. Potential employees were defined here as recent graduates of construction industry programs with entry-level technical skills. The continuous growth in and expansion of these two…

  5. Employers' Perception of Graduates with Entry-Level Technical Skills from Construction Industry Programs in Ghana and Nigeria

    ERIC Educational Resources Information Center

    Acheampong, Philip

    2013-01-01

    The purpose of this comparative study was to identify the technical skills and abilities needed by prospective employees of construction industries in Ghana and Nigeria. Potential employees were defined here as recent graduates of construction industry programs with entry-level technical skills. The continuous growth in and expansion of these two…

  6. Scientific program construction principles and time allocation scheme for the World Space Observatory—Ultraviolet mission

    NASA Astrophysics Data System (ADS)

    Malkov, Oleg; Sachkov, Mikhail; Shustov, Boris; Kaigorodov, Pavel; Yáñez, Francisco Javier; Gómez de Castro, Ana Ines

    2011-09-01

    We present scientific program construction principles and a time allocation scheme developed for the World Space Observatory—Ultraviolet (WSO-UV) mission, which is an international space observatory for observation in UV spectral range 100-300 nm. The WSO-UV consists of a 1.7 m aperture telescope with instrumentation designed to carry out high resolution spectroscopy, long-slit low resolution spectroscopy and direct sky imaging. The WSO-UV Ground Segment is under development by Spain and Russia. They will coordinate the Mission and Science Operations and provide the satellite tracking stations for the project. The WSO-UV will work as a targeted scientific observatory. Three scientific programs will be carried out at the observatory. Core Program of scientific observations, which deserves large amounts of observing time, will be defined by the WSO-UV Science Committee to allow the conduction of high impact or legacy scientific projects. Funding Bodies Program is the guaranteed time granted to each one of the national bodies funding the WSO-UV project. Guest observer program for everyone, or Open Program, consists of astronomical observations obtained with the WSO-UV by astronomers who may or may not belong to the WSO-UV international consortium. It is open to excellent scientific projects from the world-wide community and occupies up to 40% of total observational time. Apart from the particularities associated to a science mission, this new mission will be affected by a new concept of observations management, trying to maximize the scientific return of this mission, and the shared operations between the two sites located in Spain and Russia. A brief summary of the algorithmic strategies analyzed for scheduling optimization is also given in the paper.

  7. C1 neurons: the body's EMTs

    PubMed Central

    Stornetta, Ruth L.; Bochorishvili, Genrieta; DePuy, Seth D.; Burke, Peter G. R.; Abbott, Stephen B. G.

    2013-01-01

    The C1 neurons reside in the rostral and intermediate portions of the ventrolateral medulla (RVLM, IVLM). They use glutamate as a fast transmitter and synthesize catecholamines plus various neuropeptides. These neurons regulate the hypothalamic pituitary axis via direct projections to the paraventricular nucleus and regulate the autonomic nervous system via projections to sympathetic and parasympathetic preganglionic neurons. The presympathetic C1 cells, located in the RVLM, are probably organized in a roughly viscerotopic manner and most of them regulate the circulation. C1 cells are variously activated by hypoglycemia, infection or inflammation, hypoxia, nociception, and hypotension and contribute to most glucoprivic responses. C1 cells also stimulate breathing and activate brain stem noradrenergic neurons including the locus coeruleus. Based on the various effects attributed to the C1 cells, their axonal projections and what is currently known of their synaptic inputs, subsets of C1 cells appear to be differentially recruited by pain, hypoxia, infection/inflammation, hemorrhage, and hypoglycemia to produce a repertoire of stereotyped autonomic, metabolic, and neuroendocrine responses that help the organism survive physical injury and its associated cohort of acute infection, hypoxia, hypotension, and blood loss. C1 cells may also contribute to glucose and cardiovascular homeostasis in the absence of such physical stresses, and C1 cell hyperactivity may contribute to the increase in sympathetic nerve activity associated with diseases such as hypertension. PMID:23697799

  8. In-Space Assembly and Construction Technology Project Summary: Infrastructure Operations Area of the Operations Technology Program

    NASA Technical Reports Server (NTRS)

    Bush, Harold

    1991-01-01

    Viewgraphs describing the in-space assembly and construction technology project of the infrastructure operations area of the operation technology program are presented. Th objective of the project is to develop and demonstrate an in-space assembly and construction capability for large and/or massive spacecraft. The in-space assembly and construction technology program will support the need to build, in orbit, the full range of spacecraft required for the missions to and from planet Earth, including: earth-orbiting platforms, lunar transfer vehicles, and Mars transfer vehicles.

  9. 1975-76 Pennsylvania Adult Basic Education Assessment Project: An Examination of the APL Construct and Mezirow's Program Evaluation Model as a Basis for Program Improvement. Final Report.

    ERIC Educational Resources Information Center

    Lindsay, Carl A.; And Others

    A project was conducted in Pennsylvania to determine what changes might improve the effectiveness of the State's adult basic education (ABE) program. Northcutt's construct of functional competency adult performance level (APL) and Mezirow's program evaluation model provided the basis for the project's two components: APL assessment and program…

  10. Constructing an Online MCAT Preparation Program as an Alternative to On-Site Preparation for Medical School

    ERIC Educational Resources Information Center

    Navarre, Berengaria; Perez, Norma A.; Smith, Sarah Toombs

    2017-01-01

    Based on a successful five-week summer program, we constructed an online alternative to prepare Hispanic students to take the Medical College Admission Test (MCAT). We used input from student premed advisors, students, a faculty mentor, a Verbal Reasoning coach, and the program administrator. Online activities were provided to support the student…

  11. Construction of Engineering Education Program based on the Alumni's Evaluation of the Educational Outcome

    NASA Astrophysics Data System (ADS)

    Tsukamoto, Takehiko; Nishizawa, Hitoshi

    The Department of Electrical and Electronic Engineering in Toyota National College of Technology has put great emphasis on fundamental subjects, such as “electrical and electronic circuit" and “electromagnetism" more than 40 years. On the other hand, several issues of our college were clarified by the alumni's evaluation of the educational outcome in 2002. The most serious issue was low achievement of English and Social education. The alumni of all generation are dissatisfied with their low skill in English communication. As a part of the educational reforms, our department has constructed a new engineering education program focusing on fundamental ability. We introduced many problem-based-learning experiments and the compulsory subjects such as “English communication for electrical engineers" and “Engineering Ethics" into this program. Great educative results are obtained by these improvements. As a typical example, the scores of all 2nd grade students of advanced engineering course in TOEIC tests became 450 points or more. Our program has been authorized by JABEE since 2004.

  12. [The Family Health Program and the construction of a new model for primary care in Brazil].

    PubMed

    Escorel, Sarah; Giovanella, Ligia; Magalhães de Mendonça, Maria Helena; de Castro Maia Senna, Mônica

    2007-01-01

    As part of the implementation of the country's Unified Health System (Sistema Unico de Saúde), the Brazilian Government created, in the second half of the 1990s, the Family Health Program (FHP) (Programa de Saúde da Família), based on community-oriented, multidisciplinary care serving people organized into small groups. For this study, we evaluated the implementation of the FHP, based on three criteria: (1) the construction of the program as an entry point for most health needs and for access to specialized care, (2) the program's linkages with a comprehensive network of health services, and (3) the incorporation of new care practices into the health system. We found that the implementation of the FHP was far from uniform. In some municipalities the FHP is a focused program that runs in parallel with other primary care efforts. However, in other municipalities the FHP is viewed as a strategy aimed at changing the primary care model, and it partially or completely replaces preexisting primary care health units. Our research confirms a trend toward incremental change in the primary care model in Brazil. However, the expansion of the FHP in large urban areas faces several obstacles to guaranteeing all individuals access to comprehensive care with adequate clinical and collective health services, including secondary and tertiary care. The positive results that we found with some of the experiences with the FHP indicate that, in addition to increased federal financial incentives, the success of the FHP depends on creative local strategies to deal with Brazil's diversity.

  13. The cultural construction of interdisciplinarity: Doctoral student socialization in an interdisciplinary neuroscience program

    NASA Astrophysics Data System (ADS)

    Holley, Karri A.

    Using the methodologies of individual and group interviews, observation, and document analysis, this dissertation examines the experiences of doctoral students enrolled in an interdisciplinary neuroscience program. A framework drawn from theories of organizational socialization is employed to understand the influence of an interdisciplinary program on doctoral student socialization. While abundant previous literature exists in regards to the socialization of doctoral students, such literature largely concentrates the disciplinary experience. The escalating import of globalization and shifting fiscal realities place new demands on Ph.D. programs and doctoral students to work as part of collaborative research teams, produce interdisciplinary knowledge, and integrate theory and practice. The increasing influence of such factors requires a new focus on interdisciplinarity and the changing Ph.D. The goal of this dissertation is to expand the existing framework of socialization by documenting the influence of such obstacles on knowledge acquisition, identity development, and professional investment. This study focuses on how interdisciplinary identities are constructed by doctoral students through individual interaction with the social environment and cultural context. Particular attention is given to the structural and cultural obstacles that doctoral students must negotiate as they navigate an interdisciplinary program. The study expands on the previous literature regarding doctoral student socialization by focusing on identity development, specifically a student's symbolic identity as a neuroscientist, a student's disciplinary identity (related to her professional background and undergraduate experiences), and a multi-disciplinary identity that allows for connections across disciplinary boundaries. In contrast to the traditional concepts of identity which focus on boundaries and differences as an inherent part of self-definition, the structure of identity advanced

  14. Wiseman conducts BCAT-C1 experiment

    NASA Image and Video Library

    2014-07-25

    ISS040-E-076505 (25 July 2014) --- NASA astronaut Reid Wiseman, Expedition 40 flight engineer, conducts a session with the Binary Colloidal Alloy Test-C1, or BCAT-C1, experiment in the Kibo laboratory of the International Space Station. Results from this ongoing investigation of colloids ? mixtures of small particles distributed throughout a liquid ? will help materials scientists to develop new consumer products with unique properties and longer shelf lives.

  15. Wiseman conducts BCAT-C1 experiment

    NASA Image and Video Library

    2014-07-25

    ISS040-E-076507 (25 July 2014) --- NASA astronaut Reid Wiseman, Expedition 40 flight engineer, conducts a session with the Binary Colloidal Alloy Test-C1, or BCAT-C1, experiment in the Kibo laboratory of the International Space Station. Results from this ongoing investigation of colloids ? mixtures of small particles distributed throughout a liquid ? will help materials scientists to develop new consumer products with unique properties and longer shelf lives.

  16. Wiseman conducts BCAT-C1 experiment

    NASA Image and Video Library

    2014-07-25

    ISS040-E-076510 (25 July 2014) --- NASA astronaut Reid Wiseman, Expedition 40 flight engineer, conducts a session with the Binary Colloidal Alloy Test-C1, or BCAT-C1, experiment in the Kibo laboratory of the International Space Station. Results from this ongoing investigation of colloids ? mixtures of small particles distributed throughout a liquid ? will help materials scientists to develop new consumer products with unique properties and longer shelf lives.

  17. 29 CFR 2575.502c-1 - Adjusted civil penalty under section 502(c)(1).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ACT OF 1974 ADJUSTMENT OF CIVIL PENALTIES UNDER ERISA TITLE I Adjustment of Civil Penalties Under ERISA Title I § 2575.502c-1 Adjusted civil penalty under section 502(c)(1). In accordance with the... section 502(c)(1) of the Employee Retirement Income Security Act of 1974, as amended (ERISA), is...

  18. 29 CFR 2575.502c-1 - Adjusted civil penalty under section 502(c)(1).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ACT OF 1974 ADJUSTMENT OF CIVIL PENALTIES UNDER ERISA TITLE I Adjustment of Civil Penalties Under ERISA Title I § 2575.502c-1 Adjusted civil penalty under section 502(c)(1). In accordance with the... section 502(c)(1) of the Employee Retirement Income Security Act of 1974, as amended (ERISA), is...

  19. 29 CFR 2575.502c-1 - Adjusted civil penalty under section 502(c)(1).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ACT OF 1974 ADJUSTMENT OF CIVIL PENALTIES UNDER ERISA TITLE I Adjustment of Civil Penalties Under ERISA Title I § 2575.502c-1 Adjusted civil penalty under section 502(c)(1). In accordance with the... section 502(c)(1) of the Employee Retirement Income Security Act of 1974, as amended (ERISA), is...

  20. 29 CFR 2575.502c-1 - Adjusted civil penalty under section 502(c)(1).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ACT OF 1974 ADJUSTMENT OF CIVIL PENALTIES UNDER ERISA TITLE I Adjustment of Civil Penalties Under ERISA Title I § 2575.502c-1 Adjusted civil penalty under section 502(c)(1). In accordance with the... section 502(c)(1) of the Employee Retirement Income Security Act of 1974, as amended (ERISA), is...

  1. Some theoretical models and constructs generic to substance abuse prevention programs for adolescents: possible relevance and limitations for problem gambling.

    PubMed

    Evans, Richard I

    2003-01-01

    For the past several years the author and his colleagues have explored the area of how social psychological constructs and theoretical models can be applied to the prevention of health threatening behaviors in adolescents. In examining the need for the development of gambling prevention programs for adolescents, it might be of value to consider the application of such constructs and theoretical models as a foundation to the development of prevention programs in this emerging problem behavior among adolescents. In order to provide perspective to the reader, the present paper reviews the history of various psychosocial models and constructs generic to programs directed at prevention of substance abuse in adolescents. A brief history of some of these models, possibly most applicable to gambling prevention programs, are presented. Social inoculation, reasoned action, planned behavior, and problem behavior theory, are among those discussed. Some deficits of these models, are also articulated. How such models may have relevance to developing programs for prevention of problem gambling in adolescents is also discussed. However, the inherent differences between gambling and more directly health threatening behaviors such as substance abuse must, of course, be seriously considered in utilizing such models. Most current gambling prevention programs have seldom been guided by theoretical models. Developers of gambling prevention programs should consider theoretical foundations, particularly since such foundations not only provide a guide for programs, but may become critical tools in evaluating their effectiveness.

  2. SLE and C1q: A quantitative ELISA for determining C1q levels in serum

    PubMed Central

    Dillon, Skyler P.; D’Souza, Anil; Kurien, Biji T.; Scofield, R. Hal

    2010-01-01

    C1q is of interest in SLE research due to deficiencies in its activity being associated with the disease. Current published protocols for measuring C1q vary greatly in their results and ease of reproducibility. Due to this, average C1q concentrations have been reported between 56 and 276 µg/ml in non-SLE serum. We present an improved method for quantifying C1q concentrations that employs a sandwich ELISA. This method has improved precision, cost efficiency, up-scaling, reproducibility, and uses significantly lesser volumes of serum sample when compared to RID and other methods for quantifying C1q. We report an average concentration of 113±40 µg/ml for C1q in non-SLE serum. The assay designed here will be useful in the high-throughput measurement of serum C1q in SLE cases. PMID:19370710

  3. The importance of context in logic model construction for a multi-site community-based Aboriginal driver licensing program.

    PubMed

    Cullen, Patricia; Clapham, Kathleen; Byrne, Jake; Hunter, Kate; Senserrick, Teresa; Keay, Lisa; Ivers, Rebecca

    2016-08-01

    Evidence indicates that Aboriginal people are underrepresented among driver licence holders in New South Wales, which has been attributed to licensing barriers for Aboriginal people. The Driving Change program was developed to provide culturally responsive licensing services that engage Aboriginal communities and build local capacity. This paper outlines the formative evaluation of the program, including logic model construction and exploration of contextual factors. Purposive sampling was used to identify key informants (n=12) from a consultative committee of key stakeholders and program staff. Semi-structured interviews were transcribed and thematically analysed. Data from interviews informed development of the logic model. Participants demonstrated high level of support for the program and reported that it filled an important gap. The program context revealed systemic barriers to licensing that were correspondingly targeted by specific program outputs in the logic model. Addressing underlying assumptions of the program involved managing local capacity and support to strengthen implementation. This formative evaluation highlights the importance of exploring program context as a crucial first step in logic model construction. The consultation process assisted in clarifying program goals and ensuring that the program was responding to underlying systemic factors that contribute to inequitable licensing access for Aboriginal people. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Local perturbations of conservative C 1 diffeomorphisms

    NASA Astrophysics Data System (ADS)

    Buzzi, Jérôme; Crovisier, Sylvain; Fisher, Todd

    2017-09-01

    A number of techniques have been developed to perturb the dynamics of C 1-diffeomorphisms and to modify the properties of their periodic orbits. For instance, one can locally linearize the dynamics, change the tangent dynamics, or create local homoclinic orbits. These techniques have been crucial for the understanding of C 1 dynamics, but their most precise forms have mostly been shown in the dissipative setting. This work extends these results to volume-preserving and especially symplectic systems. These tools underlie our study of the entropy of C 1-diffeomorphisms in Buzzi et al (2016 (arXiv:1606.01765)). We also give an application to the approximation of transitive invariant sets without genericity assumptions.

  5. On orientifolds of c=1 orbifolds

    NASA Astrophysics Data System (ADS)

    Dijkstra, T. P. T.; Gato-Rivera, B.; Riccioni, F.; Schellekens, A. N.

    2004-10-01

    The aim of this paper is to study orientifolds of c=1 conformal field theories. A systematic analysis of the allowed orientifold projections for c=1 orbifold conformal field theories is given. We compare the Klein bottle amplitudes obtained at rational points with the orientifold projections that we claim to be consistent for any value of the orbifold radius. We show that the recently obtained Klein bottle amplitudes corresponding to exceptional modular invariants, describing bosonic string theories at fractional square radius, are also in agreement with those orientifold projections.

  6. Hereditary angioedema with normal C1 inhibitor.

    PubMed

    Bork, Konrad

    2013-11-01

    Until recently it was assumed that hereditary angioedema was a disease that results exclusively from a genetic deficiency of the C1 inhibitor. In 2000, families with hereditary angioedema, normal C1 inhibitor activity, and protein in plasma were described. Since then, numerous patients and families with that condition have been reported. Most of the patients were women. In many of the affected women, oral contraceptives, hormone replacement therapy containing estrogens, and pregnancies triggered the clinical symptoms. In some families mutations in the coagulation factor XII (Hageman factor) gene were detected.

  7. C1 Hermite shape preserving polynomial splines in R3

    NASA Astrophysics Data System (ADS)

    Gabrielides, Nikolaos C.

    2012-06-01

    The C 2 variable degree splines1-3 have been proven to be an efficient tool for solving the curve shape-preserving interpolation problem in two and three dimensions. Based on this representation, the current paper proposes a Hermite interpolation scheme, to construct C 1 shape-preserving splines of variable degree. After this, a slight modification of the method leads to a C 1 shape-preserving Hermite cubic spline. Both methods can easily be developed within a CAD system, since they compute directly (without iterations) the B-spline control polygon. They have been implemented and tested within the DNV Software CAD/CAE system GeniE. [Figure not available: see fulltext.

  8. Satellite Power System. Concept development and evaluation program, volume 6: Construction and operations

    NASA Technical Reports Server (NTRS)

    Benson, H.; Jenkins, L. M.

    1981-01-01

    The construction, operation, and maintenance requirements for a solar power satellite, including the space and ground systems, are reviewed. The basic construction guidelines are explained, and construction location options are discussed. The space construction tasks, equipment, and base configurations are discussed together with the operations required to place a solar power satellite in geosynchronous orbit. A rectenna construction technique is explained, and operation with the grid is defined. Maintenance requirements are summarized for the entire system. Key technology issues required for solar power satellite construction operations are defined.

  9. Satellite power system. Concept Development and Evaluation Program, Volume 6: construction and operations

    SciTech Connect

    Benson, H.; Jenkins, L.M.

    1981-04-01

    The construction, operation, and maintenance requirements for a solar power satellite, including the space and ground systems, are reviewed. The basic construction guidelines are explained, and construction location options are discussed. The space construction tasks, equipment, and base configurations are discussed together with the operations required to place a solar power satellite in geosynchronous orbit. A rectenna construction technique is explained, and operation with the grid is defined. Maintenance requirements are summarized for the entire system. Key technology issues required for solar power satellite construction operations are defined.

  10. Caged ceramide 1-phosphate (C1P) analogs: Novel tools for studying C1P biology.

    PubMed

    Gomez-Muñoz, Antonio; Gangoiti, Patricia; Rivera, Io-Guané; Presa, Natalia; Gomez-Larrauri, Ana; Ordoñez, Marta

    2016-01-01

    Ceramide 1-phosphate (C1P) is a bioactive sphingolipid metabolite that is produced in cells by the action of ceramide kinase (CerK) acting upon ceramide, and is also found in the circulation. C1P was first demonstrated to be mitogenic and antiapoptotic in different cell types, and was later shown to induce cell migration. Understanding the precise mechanisms by which C1P exerts its biological effects has been possible using specific photosensitive caged C1P analogues synthesized by Robert Bittman's group. These compounds are cell permeable, bypass cell plasma membrane receptors, and can be released into the cytosol upon light irradiation, thereby allowing precise determination of the intracellular mechanisms of actions of C1P. Two derivatives of N-palmitoyl-ceramide 1-phosphate have been used in most studies. In one C1P derivative the cage was 7-(N,N-diethylamino)coumarin (DECM-C1P) while in the other it was a 4-bromo-5-hydroxy-2-nitrobenzhydryl moiety (BHNB-C1P). The uncaging process released C1P in the cytosol, and this was accompanied by stimulation of cell proliferation, inhibition of apoptosis, and production of low levels of reactive oxygen species. However, intracellular accumulation of C1P did not affect chemotaxis. The caged C1P analogues allowed distinction between the extracellular events evoked by C1P, as for example through interaction with a putative cell-surface receptor, from its intracellular effects. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  11. Terminal complement complexes and C1/C1 inhibitor complexes in autoimmune thyroid disease.

    PubMed Central

    Weetman, A P; Cohen, S B; Oleesky, D A; Morgan, B P

    1989-01-01

    The potential role of complement activation and the membrane attack complex in the pathogenesis of Graves' disease and Hashimoto's thyroiditis has been investigated by measuring serum concentrations of the C1r-C1s-C1 inhibitor complex (C1/C1-inh) and the terminal complement complex (TCC), and by studying the binding to thyroid tissue of monoclonal and polyclonal antibodies against TCC neoantigens. Serum C1/C1-inh and TCC concentrations were significantly increased in 29 patients with untreated Graves' disease compared with 47 healthy subjects (P less than 0.001 for both), and decreased significantly after carbimazole treatment in 18 of these patients for whom post-treatment samples were available (P less than 0.01 and P less than 0.02, respectively). The serum TCC concentration, but not that of C1/C1-inh, was also significantly increased in 15 patients with Hashimoto's thyroiditis compared with the 47 healthy subjects (P less than 0.001). TCCs were identified by immunohistochemical staining around the thyroid follicles in thyroidectomy specimens from patients with Graves' disease (six out of six) and Hashimoto's thyroiditis (two out of two); normal thyroid tissue from two subjects showed no staining. These results suggest a role for complement, in particular the membrane attack complex in the pathogenesis of autoimmune thyroid disease. Images Fig. 3 PMID:2766576

  12. 38 CFR 17.255 - Applications for grants for programs which include construction projects.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... evidence required by § 17.254, any application for a grant for the construction of any facility, structure... application shall include complete descriptions, maps, and surveys of the construction site, and documentary...

  13. RECOMMENDED FOUNDATION BARRIER CONSTRUCTION STANDARD OF THE FLORIDA RADON RESEARCH PROGRAM

    EPA Science Inventory

    The report give results of a study to determine the causes of cracking in slab-on-grade construction, particularly for single-family residential structures in Florida, and to recommend a foundation barrier construction standard to minimize such cracking.

  14. "The Mall" and "the Plant": Choice and the Classed Construction of Possible Futures in Two Specialized Arts Programs

    ERIC Educational Resources Information Center

    Gaztambide-Fernández, Rubén; VanderDussen, Elena; Cairns, Kate

    2014-01-01

    This article explores how conceptions of choice and visions of the future are constructed within the context of specialized arts programs in two Canadian public high schools. The authors consider how discourses of the arts are implicated in the way that possible futures are envisioned differently, delimiting the range of choices available to…

  15. A Study of the Construct Validity of Six Vocational Achievement Tests in the Ohio Vocational Education Achievement Test Program.

    ERIC Educational Resources Information Center

    Hines, Constance V.; And Others

    A study examined the construct validity of six vocational achievement tests used in the Ohio Vocational Achievement Testing Program. (Subject areas covered in the tests were agricultural mechanics, carpentry, diesel mechanics, distributive education for food services personnel, fabric services, and home economics/food service.) In order to…

  16. Men's Adultery as Sickness: Metaphor, Gender Categories and the Discursive Construction of Gender Differences on Japanese Television Consultation Programs

    ERIC Educational Resources Information Center

    Saft, Scott; Ohara, Yumiko

    2009-01-01

    This article describes how Japanese TV programs adopting a consultation framework construct different realities for women and men concerning a specific social phenomenon, namely adultery. To do so, two perspectives, the theory of metaphor promoted by George Lakoff and membership category analysis, are combined toward a discursive analysis which…

  17. "The Mall" and "the Plant": Choice and the Classed Construction of Possible Futures in Two Specialized Arts Programs

    ERIC Educational Resources Information Center

    Gaztambide-Fernández, Rubén; VanderDussen, Elena; Cairns, Kate

    2014-01-01

    This article explores how conceptions of choice and visions of the future are constructed within the context of specialized arts programs in two Canadian public high schools. The authors consider how discourses of the arts are implicated in the way that possible futures are envisioned differently, delimiting the range of choices available to…

  18. Men's Adultery as Sickness: Metaphor, Gender Categories and the Discursive Construction of Gender Differences on Japanese Television Consultation Programs

    ERIC Educational Resources Information Center

    Saft, Scott; Ohara, Yumiko

    2009-01-01

    This article describes how Japanese TV programs adopting a consultation framework construct different realities for women and men concerning a specific social phenomenon, namely adultery. To do so, two perspectives, the theory of metaphor promoted by George Lakoff and membership category analysis, are combined toward a discursive analysis which…

  19. The Construction and Evaluation of a Programed Course in Mathematics Necessary for Success in Collegiate Physical Science

    ERIC Educational Resources Information Center

    Collagan, Robert B.

    1969-01-01

    Discusses the construction and evaluation of a programed course in mathematics designed to provide remedial instruction to college freshmen who scored below the 25th percentile on the ACT examination. The study involved 200 students at Morgan State College, Maryland. Dependent variables were scores on several mathematics and physics tests given…

  20. Constructing Programming Tests from an Item Pool: Pushing the Limits of Student Knowledge Using Assessment and Learning Analytics

    ERIC Educational Resources Information Center

    Ivancevic, Vladimir

    2014-01-01

    Tests targeting the upper limits of student ability could aid students in their learning. This article gives an overview of an approach to the construction of such tests in programming, together with ideas on how to implement and refine them within a learning management system.

  1. When the School Bell Rings... Juvenile Crime or Constructive Time? After-School Programs Are the Answer.

    ERIC Educational Resources Information Center

    Carpenter, Tim; Cornelius, Aisha; Francis, Ann Potter; Parsons, Lena

    Noting that the after-school hours are peak hours for Illinois juveniles to be either victims of crime or involved in criminal activity, this report provides evidence that making quality after-school programs available to all youth who need them will reduce crime and provide constructive activities for youth. The report details statistics on…

  2. Lessons learned from new construction utility demand side management programs and their implications for implementing building energy codes

    SciTech Connect

    Wise, B.K.; Hughes, K.R.; Danko, S.L.; Gilbride, T.L.

    1994-07-01

    This report was prepared for the US Department of Energy (DOE) Office of Codes and Standards by the Pacific Northwest Laboratory (PNL) through its Building Energy Standards Program (BESP). The purpose of this task was to identify demand-side management (DSM) strategies for new construction that utilities have adopted or developed to promote energy-efficient design and construction. PNL conducted a survey of utilities and used the information gathered to extrapolate lessons learned and to identify evolving trends in utility new-construction DSM programs. The ultimate goal of the task is to identify opportunities where states might work collaboratively with utilities to promote the adoption, implementation, and enforcement of energy-efficient building energy codes.

  3. Combined traumatic occiput-C1 and C1-C2 dissociation: 2 case reports.

    PubMed

    Gould, Stephen; Hishmeh, Shuriz; McKinney, Bart; Stephen, Mark

    2010-08-01

    Occiput-C1 and C1-C2 dissociations and dislocations have been well documented in the literature. However, after thorough review of the literature, we found very little in the literature regarding combined occiput-C1 and C1-C2 dissociations in adults who survived. We present 2 case reports describing the clinical presentation, initial management, operative treatment, and postoperative course of 2 patients who sustained traumatic combined occiput-C1 and C1-C2 dissociations. After initial stabilization, both patients underwent open reduction and posterior occipital-cervical fusion with segmental fixation. At recent follow-up, both patients maintain good sagittal alignment without loss of reduction, and they have radiographic progression to fusion, minimal pain, and improved neurologic function. Combined occiput-C1 and C1-C2 dissociations are rare but serious injuries. Incomplete dissociations may not be evident on initial radiographs. Computed tomography or magnetic resonance imaging is recommended for formal diagnosis. A traumatic dural tear may be present. We recommend open reduction and posterior occipital-cervical fusion with segmental fixation for these patients.

  4. Notes on Liouville theory at c{<=}1

    SciTech Connect

    McElgin, Will

    2008-03-15

    The continuation of the Liouville conformal field theory to c{<=}1 is considered. The viability of an interpretation involving a timelike boson which is the conformal factor for two-dimensional asymptotically de Sitter geometries is examined. The conformal bootstrap leads to a three-point function with a unique analytic factor which is the same as that which appears along with the fusion coefficients in the minimal models. A corresponding nonanalytic factor produces a well-defined metric on fields only when the central charge is restricted to those of the topological minimal models, and when the conformal dimensions satisfy h>(c-1)/24. However, the theories considered here have a continuous spectrum which excludes the degenerate representations appearing in the minimal models. The c=1 theory has been investigated previously using similar techniques, and is identical to a nonrational conformal field theory (CFT) which arises as a limit of unitary minimal models. When coupled to unitary matter fields, the nonunitary theories with c{<=}-2 produce string amplitudes which are similar to those of the minimal string.

  5. Using a commercial CAD system for simultaneous input to theoretical aerodynamic programs and wind-tunnel model construction

    NASA Technical Reports Server (NTRS)

    Enomoto, F.; Keller, P.

    1984-01-01

    The Computer Aided Design (CAD) system's common geometry database was used to generate input for theoretical programs and numerically controlled (NC) tool paths for wind tunnel part fabrication. This eliminates the duplication of work in generating separate geometry databases for each type of analysis. Another advantage is that it reduces the uncertainty due to geometric differences when comparing theoretical aerodynamic data with wind tunnel data. The system was adapted to aerodynamic research by developing programs written in Design Analysis Language (DAL). These programs reduced the amount of time required to construct complex geometries and to generate input for theoretical programs. Certain shortcomings of the Design, Drafting, and Manufacturing (DDM) software limited the effectiveness of these programs and some of the Calma NC software. The complexity of aircraft configurations suggests that more types of surface and curve geometry should be added to the system. Some of these shortcomings may be eliminated as improved versions of DDM are made available.

  6. Using a commercial CAD system for simultaneous input to theoretical aerodynamic programs and wind-tunnel model construction

    NASA Technical Reports Server (NTRS)

    Enomoto, F.; Keller, P.

    1984-01-01

    The Computer Aided Design (CAD) system's common geometry database was used to generate input for theoretical programs and numerically controlled (NC) tool paths for wind tunnel part fabrication. This eliminates the duplication of work in generating separate geometry databases for each type of analysis. Another advantage is that it reduces the uncertainty due to geometric differences when comparing theoretical aerodynamic data with wind tunnel data. The system was adapted to aerodynamic research by developing programs written in Design Analysis Language (DAL). These programs reduced the amount of time required to construct complex geometries and to generate input for theoretical programs. Certain shortcomings of the Design, Drafting, and Manufacturing (DDM) software limited the effectiveness of these programs and some of the Calma NC software. The complexity of aircraft configurations suggests that more types of surface and curve geometry should be added to the system. Some of these shortcomings may be eliminated as improved versions of DDM are made available.

  7. Improving safety climate through a communication and recognition program for construction: a mixed-methods study

    PubMed Central

    Sparer, Emily H; Catalano, Paul J; Herrick, Robert F; Dennerlein, Jack T

    2016-01-01

    Objectives This study aimed to evaluate the efficacy of a safety communication and recognition program (B-SAFE), designed to encourage improvement of physical working conditions and hazard reduction in construction. Methods A matched pair cluster randomized controlled trial was conducted on eight worksites (four received the B-SAFE intervention, four served as control sites) for approximately five months per site. Pre- and post-exposure worker surveys were collected at all sites (N=615, pre-exposure response rate of 74%, post-exposure response rate of 88%). Multi-level mixed-effect regression models evaluated the effect of B-SAFE on safety climate as assessed from surveys. Focus groups (N=6–8 workers/site) were conducted following data collection. Transcripts were coded and analyzed for thematic content using Atlas.ti (version 6). Results The mean safety climate score at intervention sites, as measured on a 0–50 point scale, increased 0.5 points (1%) between pre- and post-B-SAFE exposure, compared to control sites that decreased 0.8 points (1.6%). The intervention effect size was 1.64 (3.28%) (P-value=0.01) when adjusted for month the worker started on-site, total length of time on-site, as well as individual characteristics (trade, title, age, and race/ethnicity). At intervention sites, workers noted increased levels of safety awareness, communication, and teamwork compared to control sites. Conclusions B-SAFE led to many positive changes, including an improvement in safety climate, awareness, teambuilding, and communication. B-SAFE was a simple intervention that engaged workers through effective communication infrastructures and had a significant, positive effect on worksite safety. PMID:27158914

  8. Computer-based construction of gene models using the GRAIL Gene Assembly Program

    SciTech Connect

    Einstein, J.R.; Mural, R.J.; Guan, X.; Uberbacher, E.C.

    1992-09-01

    The Gene Assembly Program (GAP), a module of GRAIL, assembles and scores gene models, given a DNA sequence and the outputs of other GRAIL modules for the sequence. The latter modules determine the positions of coding regions, the positions and scores of possible splice junctions, the positions of possible translation-initiation sites, the coding strand for the gene, and the probable-translation-frame function over the sequence. GAP tests combinations of those splice junctions which are within acceptable distances from the initial estimated edges of the coding regions. Every complete gene model, comprising translation-initiation site, splice junctions and stop codon, which agrees with GAP`s set of rules is scored, and the ten highest-scoring models are saved. Each gene-model score depends on the input scores of splice junctions used in the model, their positions relative to the initial estimated edges of the included coding regions, and the degree of agreement of the entire model with the probable-translation-frame function. If error conditions are detected, the present version of GAP attempts to correct them by the insertion and/or deletion of one or more coding regions. These insertions and deletions have resulted in a net improvement of gene models, and a particularly large improvement in the recognition and characterization of very short coding regions. The results of GRAIL including the GAP module for 26 sequences from GenBank, each with a biochemically characterized single gene, are quite promising and demonstrate the feasibility of constructing largely accurate gene models strictly on the basis of sequence data.

  9. Computer-based construction of gene models using the GRAIL Gene Assembly Program

    SciTech Connect

    Einstein, J.R.; Mural, R.J.; Guan, X.; Uberbacher, E.C.

    1992-09-01

    The Gene Assembly Program (GAP), a module of GRAIL, assembles and scores gene models, given a DNA sequence and the outputs of other GRAIL modules for the sequence. The latter modules determine the positions of coding regions, the positions and scores of possible splice junctions, the positions of possible translation-initiation sites, the coding strand for the gene, and the probable-translation-frame function over the sequence. GAP tests combinations of those splice junctions which are within acceptable distances from the initial estimated edges of the coding regions. Every complete gene model, comprising translation-initiation site, splice junctions and stop codon, which agrees with GAP's set of rules is scored, and the ten highest-scoring models are saved. Each gene-model score depends on the input scores of splice junctions used in the model, their positions relative to the initial estimated edges of the included coding regions, and the degree of agreement of the entire model with the probable-translation-frame function. If error conditions are detected, the present version of GAP attempts to correct them by the insertion and/or deletion of one or more coding regions. These insertions and deletions have resulted in a net improvement of gene models, and a particularly large improvement in the recognition and characterization of very short coding regions. The results of GRAIL including the GAP module for 26 sequences from GenBank, each with a biochemically characterized single gene, are quite promising and demonstrate the feasibility of constructing largely accurate gene models strictly on the basis of sequence data.

  10. Biomechanical Evaluation of Unilateral Versus Bilateral C1 Lateral Mass-C2 Intralaminar Fixation.

    PubMed

    Bhatia, Nitin; Rama, Asheen; Sievers, Brandon; Quigley, Ryan; McGarry, Michelle H; Lee, Yu-Po; Lee, Thay Q

    2017-05-01

    Biomechanical, cadaveric study. To compare the relative stiffness of unilateral C1 lateral mass-C2 intralaminar fixation to intact specimens and bilateral C1 lateral mass-C2 intralaminar constructs. The biomechanical integrity of a unilateral C1 lateral mass-C2 intralaminar screw construct was compared to intact specimens and bilateral C1 lateral mass-C2 intralaminar screw constructs. Five human cadaveric specimens were used. Range of motion and stiffness were tested to determine the stiffness of the constructs. Unilateral fixation significantly decreased flexion/extension range of motion compared to intact (P < .001) but did not significantly affect axial rotation (P = .3) or bending range of motion (P = .3). There was a significant decrease in stiffness in extension for both unilateral and bilateral fixation techniques compared to intact (P = .04 and P = .03, respectively). There was also a significant decrease in stiffness for ipsilateral rotation for the unilateral construct compared to intact (P = .007) whereas the bilateral construct significantly increased ipsilateral rotation stiffness compared to both intact and unilateral fixation (P < .001). Bilateral constructs did show improved biomechanical properties compared to the unilateral constructs. However, unilateral C1-C2 fixation using a C1 lateral mass and C2 intralaminar screw-rod construct decreased range of motion and improved stiffness compared to the intact state with the exception of extension and ipsilateral rotation. Hence, a unilateral construct may be acceptable in clinical situations in which bilateral fixation is not possible, but an external orthosis may be necessary to achieve a fusion.

  11. Linear programming model to construct phylogenetic network for 16S rRNA sequences of photosynthetic organisms and influenza viruses.

    PubMed

    Mathur, Rinku; Adlakha, Neeru

    2014-06-01

    Phylogenetic trees give the information about the vertical relationships of ancestors and descendants but phylogenetic networks are used to visualize the horizontal relationships among the different organisms. In order to predict reticulate events there is a need to construct phylogenetic networks. Here, a Linear Programming (LP) model has been developed for the construction of phylogenetic network. The model is validated by using data sets of chloroplast of 16S rRNA sequences of photosynthetic organisms and Influenza A/H5N1 viruses. Results obtained are in agreement with those obtained by earlier researchers.

  12. Chronic C1-C2 Rotatory Subluxation Reduced by C1 Lateral Mass Screws and C2 Translaminar Screws: A Case Report.

    PubMed

    Lavelle, William F; Palomino, Kathryn; Badve, Siddharth A; Albanese, Stephen A

    C1-C2 rotatory subluxation can result from a variety or etiologies. Pediatric patients are particularly susceptible to C1-C2 rotatory subluxation. If left untreated the condition is termed an atlantoaxial rotatory fixation (AARF) and chronic neck pain and deformity can result. Patients failing conservative treatment or those with recurrent or chronic rotatory subluxation may require halo treatment or surgical intervention. This illustrative case report is about a patient with chronic C1-C2 AARF who was treated with C1 lateral mass screws and C2 translaminar screws, a treatment that has not been addressed by this technique in a pediatric population. This is a retrospective case review. After an unsuccessful attempt at reduction, an 11-year-old girl underwent surgery to treat her C1-C2 AARF. Through an all posterior approach, screws were placed bilaterally into the C1 lateral masses followed by the placement of C2 translaminar screws bilaterally. A small amount of distraction was applied through the screw construct to open up the C1-C2 articulation and the AARF was open reduced and fused. A detailed postoperative computed tomographic scan focused on the occiput C1-C2 joint confirmed the anatomical reduction of the joint complex. The patient had cosmetically pleasing relief of her torticollis and was doing well at 60 months after surgery. Level IV.

  13. Libby Mitigation Program, 2007 Annual Progress Report: Mitigation for the Construction and Operation of Libby Dam.

    SciTech Connect

    Dunnigan, James; DeShazer, J.; Garrow, L.

    2009-05-26

    basin streams and lakes. 'Mitigation for the Construction and Operation of Libby Dam' is part of the Northwest Power and Conservation Council's (NPCC) resident fish and wildlife program. The program was mandated by the Northwest Planning Act of 1980, and is responsible for mitigating damages to fish and wildlife caused by hydroelectric development in the Columbia River Basin. The objective of Phase I of the project (1983 through 1987) was to maintain or enhance the Libby Reservoir fishery by quantifying seasonal water levels and developing ecologically sound operational guidelines. The objective of Phase II of the project (1988 through 1996) was to determine the biological effects of reservoir operations combined with biotic changes associated with an aging reservoir. The objectives of Phase III of the project (1996 through present) are to implement habitat enhancement measures to mitigate for dam effects, to provide data for implementation of operational strategies that benefit resident fish, monitor reservoir and river conditions, and monitor mitigation projects for effectiveness. This project completes urgent and high priority mitigation actions as directed by the Kootenai Subbasin Plan.

  14. Development of a Program Logic Model and Evaluation Plan for a Participatory Ergonomics Intervention in Construction

    PubMed Central

    Jaegers, Lisa; Dale, Ann Marie; Weaver, Nancy; Buchholz, Bryan; Welch, Laura; Evanoff, Bradley

    2013-01-01

    Background Intervention studies in participatory ergonomics (PE) are often difficult to interpret due to limited descriptions of program planning and evaluation. Methods In an ongoing PE program with floor layers, we developed a logic model to describe our program plan, and process and summative evaluations designed to describe the efficacy of the program. Results The logic model was a useful tool for describing the program elements and subsequent modifications. The process evaluation measured how well the program was delivered as intended, and revealed the need for program modifications. The summative evaluation provided early measures of the efficacy of the program as delivered. Conclusions Inadequate information on program delivery may lead to erroneous conclusions about intervention efficacy due to Type III error. A logic model guided the delivery and evaluation of our intervention and provides useful information to aid interpretation of results. PMID:24006097

  15. Development of a program logic model and evaluation plan for a participatory ergonomics intervention in construction.

    PubMed

    Jaegers, Lisa; Dale, Ann Marie; Weaver, Nancy; Buchholz, Bryan; Welch, Laura; Evanoff, Bradley

    2014-03-01

    Intervention studies in participatory ergonomics (PE) are often difficult to interpret due to limited descriptions of program planning and evaluation. In an ongoing PE program with floor layers, we developed a logic model to describe our program plan, and process and summative evaluations designed to describe the efficacy of the program. The logic model was a useful tool for describing the program elements and subsequent modifications. The process evaluation measured how well the program was delivered as intended, and revealed the need for program modifications. The summative evaluation provided early measures of the efficacy of the program as delivered. Inadequate information on program delivery may lead to erroneous conclusions about intervention efficacy due to Type III error. A logic model guided the delivery and evaluation of our intervention and provides useful information to aid interpretation of results. © 2013 Wiley Periodicals, Inc.

  16. Successfully Implementing Net-Zero Energy Policy through the Air Force Military Construction Program

    DTIC Science & Technology

    2013-03-01

    energy building , historical data cannot be used to provide an accurate parametric estimate. Since adequate historical 76 data does not exist...2012). Due to the natural variability in construction and the limited data available regarding the construction premium required to achieve a low

  17. Evaluation of the Mandatory Construction Induction Training Program in Western Australia: Unanticipated Consequences

    ERIC Educational Resources Information Center

    Bahn, Susanne; Barratt-Pugh, Llandis

    2012-01-01

    Since January 1, 2007, Government legislation in Western Australia required all workers in construction to complete mandatory safety awareness training before they began work on site. During the implementation of this new legislation there was considerable resistance from the construction sector due to the mandatory nature of the training. The…

  18. Charge density influences C1 domain ligand affinity and membrane interactions

    PubMed Central

    Lewin, Nancy E.; Kedei, Noemi; Hill, Colin S.; Selezneva, Julia S.; Valle, Christopher J.; Woo, Wonhee; Gorshkova, Inna; Blumberg, Peter M.

    2014-01-01

    The C1 domain, which represents the recognition motif on protein kinase C for the lipophilic second messenger diacylglycerol and its ultrapotent analog the phorbol esters, has emerged as a promising therapeutic target for cancer and other indications. Potential target selectivity is markedly enhanced both because binding reflects ternary complex formation between ligand, the C1 domain, and phospholipid, and because binding drives membrane insertion of the C1 domain, permitting aspects of the C1 domain surface outside the binding site per se to influence binding energetics. Here, focusing on charged residues identified in atypical C1 domains which contribute to their loss of ligand binding activity, we show that increasing charge along the rim of the binding cleft of the protein kinase C δ C1b domain raises the requirement for anionic phospholipids. Correspondingly, it shifts the selectivity of C1 domain translocation to the plasma membrane, which is more negatively charged than internal membranes. This change in localization is most pronounced in the case of more hydrophilic ligands, which provide weaker membrane stabilization than do the more hydrophobic ligands, and thus contributes an element to the structure activity relations for C1 domain ligands. Co-expressing pairs of C1 containing constructs with differing charges each expressing a distinct fluorescent tag provided a powerful tool to demonstrate the effect of increasing charge in the C1 domain. PMID:24777910

  19. Theoretical Insights into C1 Surface Chemistry

    NASA Astrophysics Data System (ADS)

    Neurock, Matthew

    2008-03-01

    Reforming and partial oxidation of methane as well as other C1 fuels are important processes in the production of hydrogen and synthesis gas and will likely play important roles future energy strategies. Herein we use theory and simulation to examine the reactivity of methane, methanol and dimethyl ether with CO2, H2O, or O2 over supported transition metals. We systematically probe the elementary C-H bond activation as well as the oxidation pathways involved in both reforming as the oxidation of methane and other C1 intermediates over well defined transition metal surfaces, metal alloys and metal nanoparticles. The calculations demonstrate well-established trends in C-H bond activation as the result of changes in the metal, the activating molecule (methane, methanol, and DME) as well as the reaction conditions. The reaction conditions ultimately dictate the surface coverage of carbon and oxygen which have important consequences on the surface reactivity. The theoretical and simulation results are compared with well defined experiments carried out at Berkeley over supported particles.

  20. 45 CFR 2301.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) ARCTIC RESEARCH COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE UNITED STATES ARCTIC RESEARCH COMMISSION § 2301.151 Program accessibility: New...

  1. 45 CFR 2301.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) ARCTIC RESEARCH COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE UNITED STATES ARCTIC RESEARCH COMMISSION § 2301.151 Program accessibility: New...

  2. 45 CFR 2301.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) ARCTIC RESEARCH COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE UNITED STATES ARCTIC RESEARCH COMMISSION § 2301.151 Program accessibility: New...

  3. 45 CFR 2301.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) ARCTIC RESEARCH COMMISSION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE UNITED STATES ARCTIC RESEARCH COMMISSION § 2301.151 Program accessibility: New...

  4. Computer program analyzes Buckling Of Shells Of Revolution with various wall construction, BOSOR

    NASA Technical Reports Server (NTRS)

    Almroth, B. O.; Bushnell, D.; Sobel, L. H.

    1968-01-01

    Computer program performs stability analyses for a wide class of shells without unduly restrictive approximations. The program uses numerical integration, finite difference of finite element techniques to solve with reasonable accuracy almost any buckling problem for shells exhibiting orthotropic behavior.

  5. Facility Planning in the Construction Grants Program. Instructor Guide. Working for Clean Water: An Information Program for Advisory Groups.

    ERIC Educational Resources Information Center

    Buskirk, E. Drannon, Jr.; Cole, Charles A.

    Wastewater facility planning is an essential component of the federal construction grants process. Presented in this instructor's guide is a one-hour presentation on facility planning intended for citizen advisory groups. The guide is part of the Working for Clean Water Project, which also includes a supplementary audiovisual presentation.…

  6. Constructing the ScratchJr Programming Language in the Early Childhood Classroom

    ERIC Educational Resources Information Center

    Portelance, Dylan J.; Strawhacker, Amanda L.; Bers, Marina Umaschi

    2016-01-01

    This paper seeks to contribute to the growing literature on children and computer programming by focusing on a programming language for children in Kindergarten through second grade. Sixty-two students were exposed to a 6-week curriculum using ScartchJr. They learned foundational programming concepts and applied those concepts to create personally…

  7. Constructing the ScratchJr Programming Language in the Early Childhood Classroom

    ERIC Educational Resources Information Center

    Portelance, Dylan J.; Strawhacker, Amanda L.; Bers, Marina Umaschi

    2016-01-01

    This paper seeks to contribute to the growing literature on children and computer programming by focusing on a programming language for children in Kindergarten through second grade. Sixty-two students were exposed to a 6-week curriculum using ScartchJr. They learned foundational programming concepts and applied those concepts to create personally…

  8. The Use of Linear (Goal) Programming in the Construction of a Test Blueprint.

    ERIC Educational Resources Information Center

    Busch, John Christian; Taylor, Raymond G.

    The use of a variation of linear programing (goal programing) to develop a test blueprint with multiple specification requirements, is the topic of this paper. The computer program STORM was used to develop a table of test specifications for a test that would measure achievement in introductory statistics in the subdomains of frequency…

  9. Creating, Constructing, and Cultivating Professional Development within a Reggio-Inspired Early Childhood Education Program

    ERIC Educational Resources Information Center

    Haigh, Karen M.

    2009-01-01

    The study examined the professional development system of an early childhood education program which was influenced by the Reggio Emilia Approach to early learning. This multi-site program thrived within low-income, inner-city communities of Chicago. Literature connected to the program's historical context of the Settlement House and the Reggio…

  10. Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites

    PubMed Central

    Bally, Isabelle; Ancelet, Sarah; Moriscot, Christine; Gonnet, Florence; Mantovani, Alberto; Daniel, Régis; Schoehn, Guy; Arlaud, Gérard J.; Thielens, Nicole M.

    2013-01-01

    Complement C1q is a hexameric molecule assembled from 18 polypeptide chains of three different types encoded by three genes. This versatile recognition protein senses a wide variety of immune and nonimmune ligands, including pathogens and altered self components, and triggers the classical complement pathway through activation of its associated proteases C1r and C1s. We report a method for expression of recombinant full-length human C1q involving stable transfection of HEK 293-F mammalian cells and fusion of an affinity tag to the C-terminal end of the C chain. The resulting recombinant (r) C1q molecule is similar to serum C1q as judged from biochemical and structural analyses and exhibits the characteristic shape of a bunch of flowers. Analysis of its interaction properties by surface plasmon resonance shows that rC1q retains the ability of serum C1q to associate with the C1s-C1r-C1r-C1s tetramer, to recognize physiological C1q ligands such as IgG and pentraxin 3, and to trigger C1r and C1s activation. Functional analysis of rC1q variants carrying mutations of LysA59, LysB61, and/or LysC58, in the collagen-like stems, demonstrates that LysB61 and LysC58 each play a key role in the interaction with C1s-C1r-C1r-C1s, with LysA59 being involved to a lesser degree. We propose that LysB61 and LysC58 both form salt bridges with outer acidic Ca2+ ligands of the C1r and C1s CUB (complement C1r/C1s, Uegf, bone morphogenetic protein) domains. The expression method reported here opens the way for deciphering the molecular basis of the unusual binding versatility of C1q by mapping the residues involved in the sensing of its targets and the binding of its receptors. PMID:23650384

  11. 3 CFR 102.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... building that is constructed or altered by, on behalf of, or for the use of the agency shall be designed... definitions, requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as...

  12. 13 CFR 136.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Agency shall be designed, constructed, or altered so as to be readily accessible to and usable by individuals with handicaps. The definitions, requirements, and standards of the Architectural Barriers Act (42...

  13. 36 CFR 406.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... use of the agency shall be designed, constructed, or altered so as to be readily accessible to and usable by handicapped persons. The definitions, requirements, and standards of the Architectural Barriers...

  14. 5 CFR 1850.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... designed, constructed, or altered so as to be readily accessible to and usable by individuals with handicaps. The definitions, requirements, and standards of the Architectural Barriers Act (42 U.S.C. 4151...

  15. 11 CFR 9420.6 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... is constructed or altered by, on behalf of, or for the use of the Commission shall be designed..., requirements, and standards of the Architectural Barriers Act, 42 U.S.C. 4151-4157 apply to buildings covered...

  16. An Evaluation of the Right Choices Program to Determine Effectiveness in Delivering Constructive Interventions and Providing an Early Support Program in Order to Modify Behavior of First-Time Student Offenders Who Commit Drug and Violent Acts

    ERIC Educational Resources Information Center

    Barnes, Lisa B.

    2010-01-01

    The purpose of the study was to perform a program evaluation of the Right Choices Program to determine the program's effectiveness in delivering constructive interventions that modify student behavior once students have left the program and have returned to their regular learning environment. This mixed-method evaluation consisted of an…

  17. 45 CFR 1706.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY NATIONAL COMMISSION ON LIBRARIES AND INFORMATION...

  18. 45 CFR 1706.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY NATIONAL COMMISSION ON LIBRARIES AND INFORMATION...

  19. 45 CFR 1706.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY NATIONAL COMMISSION ON LIBRARIES AND INFORMATION...

  20. 45 CFR 1706.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY NATIONAL COMMISSION ON LIBRARIES AND INFORMATION...

  1. Evaluation of the mandatory construction induction training program in Western Australia: unanticipated consequences.

    PubMed

    Bahn, Susanne; Barratt-Pugh, Llandis

    2012-08-01

    Since January 1, 2007, Government legislation in Western Australia required all workers in construction to complete mandatory safety awareness training before they began work on site. During the implementation of this new legislation there was considerable resistance from the construction sector due to the mandatory nature of the training. The construction industry viewed this as an unnecessary impost as they considered that there was already sufficient safety training delivered through individual company and site inductions. In 2010, we evaluated the new Construction Induction Training (CIT) in the commercial construction sector in Western Australia to find that since 2007 there has been an unanticipated change in support for the mandatory training. The 2010 study shows a shift in the values of the safety culture for the commercial sector of the construction industry. In 2010, the industry not only supports the mandatory CIT, but is very vocal in its request to re-institute the refresher courses that were withdrawn in 2009. Indeed, 79% of respondents claimed there were measurable benefits to their business having their employees complete the CIT, while 96% claimed the CIT assisted in reducing accidents/incidents on their worksites. This 2010 study indicates that in this case, mandatory training has had a positive effect on safety culture change and gradually reduced work-related injury in the industry since 2007 to the present. The paper uses data from two studies conducted in 2006 and 2010 to highlight the unanticipated change in perception of the value of mandatory safety training in the WA construction industry to one which is positive and supportive. Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.

  2. Hereditary C1q deficiency: a new family with C1qA deficiency.

    PubMed

    Sun-Tan, Cağman; Ozgür, Tuba Turul; Kilinç, Gamze; Topaloğlu, Rezan; Gököz, Ozay; Ersoy-Evans, Sibel; Sanal, Ozden

    2010-01-01

    Hereditary deficiency of complement component C1q is a rare genetic disorder with susceptibility to recurrent infections with polysaccharide-containing encapsulated microorganisms and a high prevalence of autoimmune diseases, most often systemic lupus erythematosus (SLE). Here, we report a 29-month-old boy who presented with facial rash and history of early death of a sibling with infections, who was found to have a selective deficiency of C1q. The facial rash was composed of patchy erythematous plaques and centrally hypopigmented macules and desquamation. Two siblings had died of severe bacterial infections and his uncle had died of meningitis. Molecular study disclosed a homozygous point mutation in the C1qA chain gene. Five members of the family, including the parents and three healthy siblings, were heterozygous for this mutation.

  3. Evaluating the Facilities Planning, Design, and Construction Department: The Capital Programs Management Audit.

    ERIC Educational Resources Information Center

    Kaiser, Harvey H.; Kirkwood, Dennis M.

    2000-01-01

    Presents a diagnostic model for assessing the state of an institution's capital programs management (CPM) by delineating "work processes" which comprise that function. What capital programs management is, its resources, and its phases and work processes are described, followed by case studies of the CPM Process Model as an assessment tool. (GR)

  4. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... alterations. 2490.151 Section 2490.151 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151 Program...

  5. 45 CFR 2490.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... alterations. 2490.151 Section 2490.151 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.151 Program...

  6. Evaluating the Facilities Planning, Design, and Construction Department: The Capital Programs Management Audit.

    ERIC Educational Resources Information Center

    Kaiser, Harvey H.; Kirkwood, Dennis M.

    2000-01-01

    Presents a diagnostic model for assessing the state of an institution's capital programs management (CPM) by delineating "work processes" which comprise that function. What capital programs management is, its resources, and its phases and work processes are described, followed by case studies of the CPM Process Model as an assessment tool. (GR)

  7. 10 CFR 4.551 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....551 Section 4.551 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM THE COMMISSION Enforcement of Nondiscrimination on the Basis of Handicap in Programs or Activities Conducted by the U.S. Nuclear...

  8. Indigenous Worldviews in Intercultural Education: Teachers' Construction of Interculturalism in a Bilingual Quechua-Spanish Program

    ERIC Educational Resources Information Center

    Valdiviezo, Laura Alicia

    2010-01-01

    This paper examines teachers' implementation of a bilingual intercultural education (BIE) program in Peru. This program is inspired by global policies that promote cultural pluralism and educational access to marginalized indigenous populations. Broadly addressed in policy in Andean countries, interculturalism in Peru has remained a core…

  9. Indigenous Worldviews in Intercultural Education: Teachers' Construction of Interculturalism in a Bilingual Quechua-Spanish Program

    ERIC Educational Resources Information Center

    Valdiviezo, Laura Alicia

    2010-01-01

    This paper examines teachers' implementation of a bilingual intercultural education (BIE) program in Peru. This program is inspired by global policies that promote cultural pluralism and educational access to marginalized indigenous populations. Broadly addressed in policy in Andean countries, interculturalism in Peru has remained a core…

  10. 40 CFR 63.42 - Program requirements governing construction or reconstruction of major sources.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Accordance With Clean Air Act Sections, Sections 112(g) and 112(j) § 63.42 Program requirements governing... cause by EPA to apply the sanctions and remedies set forth in the Clean Air Act section 502(I). (c... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS...

  11. 40 CFR 63.42 - Program requirements governing construction or reconstruction of major sources.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Accordance With Clean Air Act Sections, Sections 112(g) and 112(j) § 63.42 Program requirements governing... cause by EPA to apply the sanctions and remedies set forth in the Clean Air Act section 502(I). (c... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS...

  12. 40 CFR 63.42 - Program requirements governing construction or reconstruction of major sources.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Accordance With Clean Air Act Sections, Sections 112(g) and 112(j) § 63.42 Program requirements governing... cause by EPA to apply the sanctions and remedies set forth in the Clean Air Act section 502(I). (c... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS...

  13. Department of Education's College Construction Loan Programs. Hearing before a Subcommittee of the Committee on Government Operations. House of Representatives, Ninety-Eighth Congress, Second Session.

    ERIC Educational Resources Information Center

    Congress of the U. S., Washington, DC. House Committee on Government Operations.

    This document records the hearing of a Subcommittee of the House on its 3-month investigation of the College Housing Loan Program and the Academic Facilities Loan Program, which are administered by the Department of Education. These programs have awarded about $5 billion in loans to finance the construction of dormitories, dining halls, student…

  14. Biomechanical analysis of a novel hook-screw technique for C1-2 stabilization.

    PubMed

    Reis, Marco Túlio; Nottmeier, Eric W; Reyes, Phillip M; Baek, Seungwon; Crawford, Neil R

    2012-09-01

    The Food and Drug Administration has not cleared the following medical devices for the use described in this study. The following medical devices are being discussed for an off-label use: cervical lateral mass screws. As an alternative for cases in which the anatomy and spatial relationship between C-2 and a vertebral artery precludes insertion of C-2 pedicle/pars or C1-2 transarticular screws, a technique that includes opposing laminar hooks (claw) at C-2 combined with C-1 lateral mass screws may be used. The biomechanical stability of this alternate technique was compared with that of a standard screw-rod technique in vitro. Flexibility tests were performed in 7 specimens (occiput to C-3) in the following 6 different conditions: 1) intact; 2) after creating instability and attaching a posterior cable/graft at C1-2; 3) after removing the graft and attaching a construct comprising C-1 lateral mass screws and C-2 laminar claws; 4) after reattaching the posterior cable-graft at C1-2 (posterior hardware still in place); 5) after removing the posterior cable-graft and laminar hooks and placing C-2 pedicle screws interconnected to C-1 lateral mass screws via rod; and 6) after reattaching the posterior cable-graft at C1-2 (screw-rod construct still in place). All types of stabilization significantly reduced the range of motion, lax zone, and stiff zone compared with the intact condition. There was no significant biomechanical difference in terms of range of motion or lax zone between the screw-rod construct and the screw-claw-rod construct in any direction of loading. The screw-claw-rod technique restricts motion much like the standard Harms technique, making it an acceptable alternative technique when aberrant arterial anatomy precludes the placement of C-2 pars/pedicle screws or C1-2 transarticular screws.

  15. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public Health... investigators engaged in biomedical research, and to broaden the opportunities for participation in...

  16. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public Health... investigators engaged in biomedical research, and to broaden the opportunities for participation in...

  17. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public Health... investigators engaged in biomedical research, and to broaden the opportunities for participation in...

  18. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public Health... investigators engaged in biomedical research, and to broaden the opportunities for participation in...

  19. 42 CFR 52c.1 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH... Biomedical Research Support Program) awarded in accordance with section 301(a)(3) of the Public Health... investigators engaged in biomedical research, and to broaden the opportunities for participation in...

  20. 44 CFR 16.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... altered by, on behalf of, or for the use of the agency shall be designed, constructed, or altered so as to... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to...

  1. 36 CFR 812.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., or for the use of the agency shall be designed, constructed, or altered so as to be readily... Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to...

  2. 5 CFR 1636.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of, or for the use of the agency shall be designed, constructed, or altered so as to be readily... Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to...

  3. 36 CFR 1208.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... altered by, on behalf of, or for the use of the agency shall be designed, constructed, or altered so as to... standards of the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to...

  4. 5 CFR 2416.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... use of the agency shall be designed, constructed, or altered so as to be readily accessible to and... Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to...

  5. 5 CFR 1207.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., or for the use of the agency shall be designed, constructed, or altered so as to be readily... the Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19...

  6. 36 CFR 909.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of, or for the use of the agency shall be designed, constructed, or altered so as to be readily... Architectural Barriers Act (42 U.S.C. 4151-4157), as established in 41 CFR 101-19.600 to 101-19.607, apply to...

  7. Predators of Knowledge Construction: Interpreting Students' Metacognition in an Amusement Park Physics Program

    ERIC Educational Resources Information Center

    Anderson, David; Nashon, Samson

    2007-01-01

    It is recognized widely that learning is a dynamic and idiosyncratic process of construction and reconstruction of concepts in response to new experiences. It is influenced by the learner's prior knowledge, motivation, and sociocultural context. This study investigated how year 11 and 12 physics students' metacognition influences the development…

  8. Task Inventory Construction. Evaluation of the Marine Corps Task Analysis Program. Technical Report No. 14.

    ERIC Educational Resources Information Center

    Kishi, Akemi

    To aid in the construction of effective task analysis inventories, this technical report discusses: (1) an optimum questionnaire length that adequately covers Marine tasks without unduly fatiguing respondents; (2) procedures for the phrasing of task statements to avoid ambiguities and be understandable to as broad a range of Marines as is…

  9. Citizen Oversight of Public School Construction Programs: In Search of Promising Practice.

    ERIC Educational Resources Information Center

    2003

    This paper asserts that one part of a comprehensive control system for school construction projects is a citizen oversight committee. It suggests that citizen oversight committees are a cost-effective and politically important method for supplementing a school board in its monitoring and oversight functions. Inaddition, the committee acts as a…

  10. Predators of Knowledge Construction: Interpreting Students' Metacognition in an Amusement Park Physics Program

    ERIC Educational Resources Information Center

    Anderson, David; Nashon, Samson

    2007-01-01

    It is recognized widely that learning is a dynamic and idiosyncratic process of construction and reconstruction of concepts in response to new experiences. It is influenced by the learner's prior knowledge, motivation, and sociocultural context. This study investigated how year 11 and 12 physics students' metacognition influences the development…

  11. Mid-Atlantic Regional Training Center for Residential Construction Trades. Final Program Evaluation Report.

    ERIC Educational Resources Information Center

    Wasdyke (R. G.) & Associates, Annapolis, MD.

    A group of partners headed by the Home Builders Institute (HBI) created the Mid-Atlantic Regional Training (MART) Center for Residential Construction, with a primary focus on providing education and training services related to the masonry and carpentry trades at existing institutions in the District of Columbia, Maryland, Virginia, and West…

  12. A TEACHING PROGRAM FOR INDUSTRIAL TECHNOLOGY, THE WORLD OF CONSTRUCTION. (TITLE SUPPLIED).

    ERIC Educational Resources Information Center

    Illinois Univ., Champaign.

    THE DAILY SCHEDULE IS GIVEN FOR THE INDUSTRIAL ARTS CURRICULUM PROJECT'S FIRST YEAR COURSE IN CONSTRUCTION. INFORMATION TOPICS AND ALLOTTED CLASSTIME ARE GIVEN FOR 170 DAYS OF INSTRUCTION. CATEGORIES IN THE SCHEDULE ARE -- (1) READING ASSIGNMENT, (2) WORKBOOK, (3) PRESENTATION, (4) DISCUSSION, (5) STUDENT ACTIVITY, (6) LAB MANUAL, (7) LAB…

  13. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (NOV 2009) (a...

  14. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (OCT 2013) (a...

  15. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (JUN 2011) (a...

  16. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (MAY 2012) (a...

  17. 48 CFR 252.225-7045 - Balance of Payments Program-Construction Material Under Trade Agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Balance of Payments... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.225-7045 Balance of Payments... clause: Balance of Payments Program—Construction Material Under Trade Agreements (AUG 2013) (a...

  18. Structural and functional aspects of C1-inhibitor.

    PubMed

    Bos, Ineke G A; Hack, C Erik; Abrahams, Jan Pieter

    2002-09-01

    C1-Inh is a serpin that inhibits serine proteases from the complement and the coagulation pathway. C1-Inh consists of a serpin domain and a unique N-terminal domain and is heavily glycosylated. Non-functional mutants of C1-Inh can give insight into the inhibitory mechanism of C1-Inh. This review describes a novel 3D model of C1-Inh, based on a newly developed homology modelling method. This model gives insight into a possible potentiation mechanism of C1-Inh and based on this model the essential residues for efficient inhibition by C1-Inh are discussed.

  19. A Concept of Constructing a Common Information Space for High Tech Programs Using Information Analytical Systems

    NASA Astrophysics Data System (ADS)

    Zakharova, Alexandra A.; Kolegova, Olga A.; Nekrasova, Maria E.

    2016-04-01

    The paper deals with the issues in program management used for engineering innovative products. The existing project management tools were analyzed. The aim is to develop a decision support system that takes into account the features of program management used for high-tech products: research intensity, a high level of technical risks, unpredictable results due to the impact of various external factors, availability of several implementing agencies. The need for involving experts and using intelligent techniques for information processing is demonstrated. A conceptual model of common information space to support communication between members of the collaboration on high-tech programs has been developed. The structure and objectives of the information analysis system “Geokhod” were formulated with the purpose to implement the conceptual model of common information space in the program “Development and production of new class mining equipment - “Geokhod”.

  20. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR... CONDUCTED BY THE COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.151 Program...

  1. 41 CFR 51-10.151 - Program accessibility: New construction and alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Other Provisions Relating to Public Contracts COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR... CONDUCTED BY THE COMMITTEE FOR PURCHASE FROM PEOPLE WHO ARE BLIND OR SEVERELY DISABLED § 51-10.151 Program...

  2. Automatic construction of image inspection algorithm by using image processing network programming

    NASA Astrophysics Data System (ADS)

    Yoshimura, Yuichiro; Aoki, Kimiya

    2017-03-01

    In this paper, we discuss a method for automatic programming of inspection image processing. In the industrial field, automatic program generators or expert systems are expected to shorten a period required for developing a new appearance inspection system. So-called "image processing expert system" have been studied for over the nearly 30 years. We are convinced of the need to adopt a new idea. Recently, a novel type of evolutionary algorithms, called genetic network programming (GNP), has been proposed. In this study, we use GNP as a method to create an inspection image processing logic. GNP develops many directed graph structures, and shows excellent ability of formulating complex problems. We have converted this network program model to Image Processing Network Programming (IPNP). IPNP selects an appropriate image processing command based on some characteristics of input image data and processing log, and generates a visual inspection software with series of image processing commands. It is verified from experiments that the proposed method is able to create some inspection image processing programs. In the basic experiment with 200 test images, the success rate of detection of target region was 93.5%.

  3. Characterization of C1 inhibitor binding to neutrophils.

    PubMed Central

    Chang, N S; Boackle, R J; Leu, R W

    1991-01-01

    In a previous study we have isolated neutrophil membrane proteins that non-covalently bind to native C1-INH (105,000 MW) and a non-functional, degraded C1-INH (88,000 MW; C1-INH-88). To further characterize the binding nature, we have designed a novel kinetic C1 titration assay which enables not only a quantification of the removal of fluid-phase C1-INH by neutrophils, but also a concomitant measure of residual C1-INH function. Native C1-INH, when adsorbed to EDTA-pretreated neutrophils, lost its function in the inhibition of fluid-phase C1. The non-functional C1-INH-88, which is probably devoid of a reactive centre, was found to block the binding of native C1-INH to neutrophils. Pretreatment of neutrophils with serine esterase inhibitors did not abrogate binding capacity of the cells for C1-INH, whereas the binding affinity for C1-INH was lost when the cells were pretreated with trypsin. An array of human peripheral blood leucocytes and several lymphoid cell lines has surface binding sites for C1-INH, but not on human erythrocytes and U937 cells. Binding was further confirmed using (i) C1-INH-microsphere beads to neutrophils, in which the binding was blocked when pretreating neutrophils with excess C1-INH or with trypsin, and (ii) radiolabelled C1-INH to neutrophils, which was competitively blocked by unlabelled non-functional C1-INH-88. Desialylation of C1-INH significantly reduced its binding affinity for neutrophils, indicating that the membrane receptor sites on neutrophils could be specific for the binding of sialic acid residues on C1-INH. Overall, our studies indicate that neutrophils or other leucocytes possess specific surface binding sites for the sialic acid-containing portion of C1-INH. PMID:2045131

  4. Classical complement pathway component C1q: purification of human C1q, isolation of C1q collagen-like and globular head fragments and production of recombinant C1q-derivatives. Functional characterization.

    PubMed

    Kojouharova, Mihaela

    2014-01-01

    The classical complement pathway (CCP) activation is a multimolecular complex, composed of three subcomponents namely C1q, C1r, and C1s. C1q is the recognition subunit of this complex and its binding to the specific targets leads to the formation of active C1, which in turn activates the CCP in an immunoglobulin-dependent or -independent manner. C1q is a hexameric glycoprotein composed of 18 polypeptide chains of three different types (A, B, and C), organized in two fragments-collagen-like (CLR) and globular head (gC1q) possessing different functional activity. The contemporary knowledge of the C1q structure allows the isolation and purification of a C1q molecule from serum by combination of different chromatography procedures including ion-exchange, size-exclusion, and affinity chromatography, as well as the isolation of CLR and gC1q by limited enzymatic hydrolysis of the native C1q molecule. In this chapter, we described methods for purification of human C1q and its CLR and gC1q fragments, as well as methods for their biochemical and functional characterization. The production and purification of recombinant C1q derivatives ghA, ghB, and ghC (globular fragments of the individual C1q chains) are also presented.

  5. Automatic planning and programming for robotic construction of planetary/lunar structures

    SciTech Connect

    Boissiere, P.T.

    1997-04-01

    Many difficult material handling needs exist in remote unstructured environments. Currently these operations are accomplished using personnel in direct contact with the hazards. A safe and cost-effective alternative to this approach is the use of intelligent robotic systems for the excavation, handling, transport and manipulation of materials during remote construction operations. A robotic system designed for these tasks has been developed at Sandia National Laboratories which successfully integrates computer controlled manipulation and mobility to deliver these needed robotic capabilities in remote applications such as planetary operations. The mobile robot, RETRVIR, incorporates advanced developments in the integration of sensors, advanced computing environments, and graphical user interfaces. The addition of these elements in the control of remotely operated equipment have shown great promise for reducing the cost of remote construction while providing faster and safer operations.

  6. Immunogenicity assessment of recombinant human c1-inhibitor: an integrated analysis of clinical studies.

    PubMed

    Hack, C Erik; Mannesse, Maurice; Baboeram, Aartie; Oortwijn, Beatrijs; Relan, Anurag

    2012-10-01

    Recombinant human C1-inhibitor (rhC1INH) is used to treat acute angioedema attacks in hereditary angioedema (HAE) due to a genetic C1INH deficiency. Recombinant proteins in general may induce antibody responses and therefore evaluation of such responses in the target population is an essential step in the clinical development program of a recombinant protein. Here we report the assessment of the immunogenicity of rhC1INH in symptomatic HAE patients. Blood samples collected before and after administration of rhC1INH were tested for antibodies against plasma-derived (pd) or rhC1INH, or against host-related impurities (HRI). Above cut-off screening results were confirmed with displacement assays, and also tested for neutralizing anti-C1INH antibodies. Finally, the relation of antibodies to clinical efficacy and safety of rhC1INH was analyzed. Data from 155 HAE patients who received 424 treatments with rhC1INH were analyzed. 1.5% of all pre-exposure tests and 1.3% of all post-exposure tests were above the cut-off level in the screening assay for anti-C1INH antibodies. Six patients (3.9%) had anti-rhC1INH antibodies positive in the confirmatory assay. In two patients, confirmed antibodies were pre-existing with no increase post-exposure; in three patients, the antibodies occurred on a single occasion post-exposure; and in one patient, on subsequent occasions post-exposure. Neutralizing anti-pdC1INH antibodies were not found. Anti-HRI antibodies in the screening assay occurred in <0.7% of the tests before exposure to rhC1INH, in <1.9% after first exposure and in <3.1% after repeat treatment with rhC1INH. Five patients had anti-HRI antibodies positive in the confirmatory assay. In one patient, the antibodies were pre-existing, whereas in three of the 155 rhC1INH-treated patients (1.9%), confirmed anti-HRI antibodies occurred at more time points. Antibody findings were not associated with altered efficacy of rhC1INH or adverse events. These results indicate a reassuring

  7. Assessing the construct validity of five nutrient profiling systems using diet modeling with linear programming.

    PubMed

    Clerfeuille, E; Vieux, F; Lluch, A; Darmon, N; Rolf-Pedersen, N

    2013-09-01

    Nutrient profiling classifies individual food products according to their nutrient content. According to the WHO (World Health Organization), validation is a key step in the development of a nutrient profiling system. The aim was to assess the construct validity of five European nutrient profiling systems (Choices, Keyhole, (AFSSA), European Commission (EC) system and FoodProfiler). Construct validity was assessed for each of the five-selected nutrient profiling systems by testing whether healthy foods (that is, identified as eligible by the system) make healthy diets, and unhealthy foods (that is, non-eligible) make unhealthy diets, using diet modeling. The AFSSA, EC and FoodProfiler systems were identified as valid, but differences in their levels of permissiveness suggested some misclassified food products. The two other systems failed the construct validity assessment. Among these three systems, the EC system is the less demanding in terms of nutritional information, it would, therefore, be the easiest to implement for regulating nutrition and health claims in Europe.

  8. Chart Your Own Course: Class Difference and the Construction of Personal Trajectories in Career Portfolio Programs

    ERIC Educational Resources Information Center

    Collin, Ross

    2011-01-01

    In this article, I examine two students' experiences with their schools' career portfolio programs. These initiatives call students to assemble papers, projects, and nonacademic items and to present them in ways that chart their personal trajectories into paid work. Shortly before graduation, students present their portfolios to exit interview…

  9. Application of Matrix Outcome Mapping to Constructively Align Program Outcomes and Course Outcomes in Higher Education

    ERIC Educational Resources Information Center

    Mazouz, Abdelkader; Crane, Keenan

    2013-01-01

    Establishing a link between Course Learning Outcomes (LOs) and Program Outcomes (POs) while assessing the course contents and delivery are among the most challenging issues in Higher Education. In the present study two forms were generated based on specific Course Learning Outcomes identified in the syllabus at the beginning of the teaching term:…

  10. An Exploratory Study of the Impact of College Student Leadership Programs upon the Construct of Mindfulness

    ERIC Educational Resources Information Center

    Horowitz, Rich

    2012-01-01

    Mindfulness is a key skill that produces the greater psychological awareness identified by most leadership scholars as being essential to effective leadership. This study conducted an exploratory assessment of the effectiveness of mindfulness-based cocurricular collegiate leadership programs through pre- and post-participation application of the…

  11. Constructing the American Child in the 1920's: Radio Programs for Parents.

    ERIC Educational Resources Information Center

    Johnson, Ann

    To explore dominant theoretical influences on parent education, emerging views of child nature and development, and implicit strategies for recruiting parental agreement and participation, this study analyzed "Radio Talk," a 1920s parent education program produced by child psychologists in Minnesota. A qualitative analysis of the…

  12. The Effectiveness of a Re-Constructed Leadership Program through the Eyes of the Stakeholders.

    ERIC Educational Resources Information Center

    Martin, Barbara N.; Johnson, Judy A.

    2002-01-01

    Report of a study of the leadership competencies of rural principals in Missouri who were prepared through the Interstate School Leaders Licensure Consortium Standards. Findings indicate that a standards-based program and collaboration between the training institution and public schools results in well-prepared leaders. (Contains 1 table and 17…

  13. 2005 Mississippi Curriculum Framework: Secondary Building Trades. (Program CIP: 46.0000 - Construction Trades, General)

    ERIC Educational Resources Information Center

    Jernigan, Jarvis; Manning, Phillip; Matkins, Billy

    2005-01-01

    Secondary vocational-technical education programs in Mississippi are faced with many challenges resulting from sweeping educational reforms at the national and state levels. Schools and teachers are increasingly being held accountable for providing true learning activities to every student in the classroom. This accountability is measured through…

  14. Green Construction and Energy Training Program for At-Risk Individuals: A Case Study

    ERIC Educational Resources Information Center

    del Puerto, Carla Lopez; Crowson, Adrienne

    2013-01-01

    Training individuals who are at risk of unemployment/underemployment to increase their employability is a mission of many nonprofit agencies. These training programs, often supported by government funding, attempt to reduce these individuals' reliance on government assistance. The purpose of this study is to obtain hard data and an in-depth…

  15. Planning a Program of School Plant Construction. Research Report, School Plant Planning Series.

    ERIC Educational Resources Information Center

    Utah State Board of Education, Salt Lake City.

    The importance of long-term planning, and undesirable conditions resulting from failure to plan, are stressed. General procedures named as essential are--(1) the official approval of the Board of Education before the administration proceeds with long-range planning, (2) the design of the school plant around the educational program it is to serve,…

  16. An Exploratory Study of the Impact of College Student Leadership Programs upon the Construct of Mindfulness

    ERIC Educational Resources Information Center

    Horowitz, Rich

    2012-01-01

    Mindfulness is a key skill that produces the greater psychological awareness identified by most leadership scholars as being essential to effective leadership. This study conducted an exploratory assessment of the effectiveness of mindfulness-based cocurricular collegiate leadership programs through pre- and post-participation application of the…

  17. Construction safety program for the National Ignition Facility Appendix A: Safety Requirements

    SciTech Connect

    Cerruti, S.J.

    1997-01-14

    These rules apply to all LLNL employees, non-LLNL employees (including contract labor, supplemental labor, vendors, personnel matrixed/assigned from other National Laboratories, participating guests, visitors and students) and construction contractors/subcontractors. The General Safety and Health rules shall be used by management to promote accident prevention through indoctrination, safety and health training and on-the-job application. As a condition for contracts award, all contractors and subcontractors and their employees must certify on Form S & H A-1 that they have read and understand, or have been briefed and understand, the National Ignition Facility OCIP Project General Safety Rules.

  18. Construction of pore network models for Berea and Fontainebleau sandstones using non-linear programing and optimization techniques

    NASA Astrophysics Data System (ADS)

    Sharqawy, Mostafa H.

    2016-12-01

    Pore network models (PNM) of Berea and Fontainebleau sandstones were constructed using nonlinear programming (NLP) and optimization methods. The constructed PNMs are considered as a digital representation of the rock samples which were based on matching the macroscopic properties of the porous media and used to conduct fluid transport simulations including single and two-phase flow. The PNMs consisted of cubic networks of randomly distributed pores and throats sizes and with various connectivity levels. The networks were optimized such that the upper and lower bounds of the pore sizes are determined using the capillary tube bundle model and the Nelder-Mead method instead of guessing them, which reduces the optimization computational time significantly. An open-source PNM framework was employed to conduct transport and percolation simulations such as invasion percolation and Darcian flow. The PNM model was subsequently used to compute the macroscopic properties; porosity, absolute permeability, specific surface area, breakthrough capillary pressure, and primary drainage curve. The pore networks were optimized to allow for the simulation results of the macroscopic properties to be in excellent agreement with the experimental measurements. This study demonstrates that non-linear programming and optimization methods provide a promising method for pore network modeling when computed tomography imaging may not be readily available.

  19. Proteolytic inactivation of plasma C1- inhibitor in sepsis.

    PubMed Central

    Nuijens, J H; Eerenberg-Belmer, A J; Huijbregts, C C; Schreuder, W O; Felt-Bersma, R J; Abbink, J J; Thijs, L G; Hack, C E

    1989-01-01

    Activation of both the complement system and the contact system of intrinsic coagulation is implicated in the pathophysiology of sepsis. Because C1 inhibitor (C1-Inh) regulates the activation of both cascade systems, we studied the characteristics of plasma C1-Inh in 48 patients with severe sepsis on admission to the Intensive Care Unit at the Free University of Amsterdam. The ratio between the level of functional and antigenic C1-Inh (functional index) was significantly reduced in the patients with sepsis compared with healthy volunteers (P = 0.004). The assessment of modified (cleaved), inactive C1-Inh (iC1-Inh), and complexed forms of C1-Inh (nonfunctional C1-Inh species) revealed that the reduced functional index was mainly due to the presence of iC1-Inh. On SDS-PAGE, iC1-Inh species migrated with a lower apparent molecular weight (Mr 98,000, 91,000, and 86,000) than native C1-Inh (Mr 110,000). Elevated iC1-Inh levels (greater than or equal to 0.13 microM) were found in 81% of all patients, sometimes up to 1.6 microM. Levels of iC1-Inh on admission appeared to be of prognostic value: iC1-Inh was higher in 27 patients who died than in 21 patients who survived (P = 0.003). The mortality in 15 patients with iC1-Inh levels up to 0.2 microM was 27%, but in 12 patients with plasma iC1-Inh exceeding 0.44 microM, the mortality was 83%. The overall mortality in the patients with sepsis was 56%. We propose that the cleavage of C1-Inh in patients with sepsis reflects processes that play a major role in the development of fatal complications during sepsis. Images PMID:2668333

  20. C1 inhibitor functional deficiency in systemic lupus erythematosus (SLE).

    PubMed Central

    Jazwinska, E C; Gatenby, P A; Dunckley, H; Serjeantson, S W

    1993-01-01

    C1 inhibitor (C1-inh) was assayed in eight SLE patients presenting with consistently low levels of intact C4. C1-inh antigenic levels were normal in all patients; however, the function of the C1-inh tested against C1s and C1r was variable and outside the normal functional range in seven of the eight patients. The molecular weight of patients' C1-inh protein was 105 kD, corresponding to the size of the intact molecule. The C1-inh gene was analysed in all patients. Restriction fragments generated with TaqI, PstI and HgiAI gave no indication of a major C1-inh gene rearrangement. Direct genomic sequencing of exon VIII revealed three polymorphic point mutations, but there were no changes from the normal gene in or around the reactive-centre residue of C1-inh. Furthermore, we found no evidence for a C1-inh autoantibody in patients which could affect normal C1-inh function in vitro. These results indicate that the etiology of C1-inh dysfunction in SLE is heterogeneous and distinct from that reported in either hereditary or acquired angioedema. PMID:8485912

  1. [Constructing an ACP Simulation-Situation Communication Training Program for Patients With Chronic Kidney Disease].

    PubMed

    Chen, Jui-O; Lin, Chiu-Chu

    2016-06-01

    The aging population and changing lifestyles have lead to the increased general risk of chronic kidney disease. Taiwan currently has the highest incidence and prevalence of end-stage renal disease (ESRD) of any country or region in the world. Hemodialysis patients must endure comorbidities and face the uncertainties of death. The best way to achieve a good death is for patients to sign advance care planning (ACP). However, the key factors contributing to low ACP signature rates have been the lack of communication skills and related training among medical staffs. This article explores the dilemma of ACP using an example of chronic kidney disease (CKD) and proposes a theory-based approach to develop a theoretical framework for an ACP simulation-situation communication training program that integrates the simulation situation model, PREPARED model, and scaffolding theory. Readers may use this framework to design ACP simulation-situation communication training programs that conform to their own conditions and then test the effectiveness and feasibility of these programs in clinical settings.

  2. Constructing a resilience index for the Enhanced Critical Infrastructure Protection Program

    SciTech Connect

    Fisher, R. E.; Bassett, G. W.; Buehring, W. A.; Collins, M. J.; Dickinson, D. C.; Eaton, L. K.; Haffenden, R. A.; Hussar, N. E.; Klett, M. S.; Lawlor, M. A.; Millier, D. J.; Petit, F. D.; Peyton, S. M.; Wallace, K. E.; Whitfield, R. G.; Peerenboom, J P

    2010-10-14

    Following recommendations made in Homeland Security Presidential Directive 7, which established a national policy for the identification and increased protection of critical infrastructure and key resources (CIKR) by Federal departments and agencies, the U.S. Department of Homeland Security (DHS) in 2006 developed the Enhanced Critical Infrastructure Protection (ECIP) program. The ECIP program aimed to provide a closer partnership with state, regional, territorial, local, and tribal authorities in fulfilling the national objective to improve CIKR protection. The program was specifically designed to identify protective measures currently in place in CIKR and to inform facility owners/operators of the benefits of new protective measures. The ECIP program also sought to enhance existing relationships between DHS and owners/operators of CIKR and to build relationships where none existed (DHS 2008; DHS 2009). In 2009, DHS and its protective security advisors (PSAs) began assessing CIKR assets using the ECIP program and ultimately produced individual protective measure and vulnerability values through the protective measure and vulnerability indices (PMI/VI). The PMI/VI assess the protective measures posture of individual facilities at their 'weakest link,' allowing for a detailed analysis of the most vulnerable aspects of the facilities (Schneier 2003), while maintaining the ability to produce an overall protective measures picture. The PMI has six main components (physical security, security management, security force, information sharing, protective measures assessments, and dependencies) and focuses on actions taken by a facility to prevent or deter the occurrence of an incident (Argonne National Laboratory 2009). As CIKR continue to be assessed using the PMI/VI and owners/operators better understand how they can prevent or deter incidents, academic research, practitioner emphasis, and public policy formation have increasingly focused on resilience as a necessary

  3. Plasma levels of C1- inhibitor complexes and cleaved C1- inhibitor in patients with hereditary angioneurotic edema.

    PubMed Central

    Cugno, M; Nuijens, J; Hack, E; Eerenberg, A; Frangi, D; Agostoni, A; Cicardi, M

    1990-01-01

    C1- inhibitor (C1(-)-Inh) catabolism in plasma of patients with hereditary angioneurotic edema (HANE) was assessed by measuring the complexes formed by C1(-)-Inh with its target proteases (C1-s, Factor XIIa, and kallikrein) and a modified (cleaved) inactive form of C1(-)-Inh (iC1(-)-Inh). This study was performed in plasma from 18 healthy subjects and 30 patients with HANE in remission: 20 with low antigen concentration (type I) and 10 (from 5 different kindreds) with dysfunctional protein (type II). Both type-I and type-II patients had increased C1(-)-C1(-)-Inh complexes (P less than 0.0001), which in type I inversely correlated with the levels of C1(-)-Inh (P less than 0.001). iC1(-)-Inh was normal in all type-I patients and in type-II patients from three families with increased C1(-)-Inh antigen, whereas iC1(-)-Inh was higher than 20 times the normal values in patients from the remaining two families with C1(-)-Inh antigen in the normal range. None of the subjects had an increase of either Factor XIIa-C1(-)-Inh or kallikrein-C1(-)-Inh complexes. This study shows that the hypercatabolism of C1(-)-Inh in HANE patients at least in part occurs via the formation of complexes with C1- and that genetically determined differences in catabolism of dysfunctional C1(-)-Inh proteins are present in type-II patients. Images PMID:2318974

  4. A trial of a job-specific workers' health surveillance program for construction workers: study protocol

    PubMed Central

    2011-01-01

    Background Dutch construction workers are offered periodic health examinations. This care can be improved by tailoring this workers health surveillance (WHS) to the demands of the job and adjust the preventive actions to the specific health risks of a worker in a particular job. To improve the quality of the WHS for construction workers and stimulate relevant job-specific preventive actions by the occupational physician, we have developed a job-specific WHS. The job-specific WHS consists of modules assessing both physical and psychological requirements. The selected measurement instruments chosen, are based on their appropriateness to measure the workers' capacity and health requirements. They include a questionnaire and biometrical tests, and physical performance tests that measure physical functional capabilities. Furthermore, our job-specific WHS provides occupational physicians with a protocol to increase the worker-behavioural effectiveness of their counselling and to stimulate job-specific preventive actions. The objective of this paper is to describe and clarify our study to evaluate the behavioural effects of this job-specific WHS on workers and occupational physicians. Methods/Design The ongoing study of bricklayers and supervisors is a nonrandomised trial to compare the outcome of an intervention (job-specific WHS) group (n = 206) with that of a control (WHS) group (n = 206). The study includes a three-month follow-up. The primary outcome measure is the proportion of participants who have undertaken one or more of the preventive actions advised by their occupational physician in the three months after attending the WHS. A process evaluation will be carried out to determine context, reach, dose delivered, dose received, fidelity, and satisfaction. The present study is in accordance with the TREND Statement. Discussion This study will allow an evaluation of the behaviour of both the workers and occupational physician regarding the preventive actions

  5. The neural guidance receptor Plexin C1 delays melanoma progression

    PubMed Central

    Chen, Y; Soong, J; Mohanty, S; Xu, L; Scott, G

    2013-01-01

    Plexin C1 is a type I transmembrane receptor with intrinsic R-Ras GTPase activity, which regulates cytoskeletal remodeling and adhesion in normal human melanocytes. Melanocytes are pigment-producing cells of the epidermis, precursors for melanoma, and express high levels of Plexin C1, which is lost in melanoma in vitro and in vivo. To determine if Plexin C1 is a tumor suppressor for melanoma, we introduced Plexin C1 into a primary human melanoma cell line, and phenotypes including migration, apoptosis, proliferation and tumor growth in mice were analyzed. Complimentary studies in which Plexin C1 was silenced in human melanocytes were performed. Plexin C1 significantly inhibited migration and proliferation in melanoma, whereas in melanocytes, loss of Plexin C1 increased migration and proliferation. In mouse xenografts, Plexin C1 delayed tumor growth of melanoma at early time points, but tumors eventually escaped the suppressive effects of Plexin C1, due to Plexin C1-dependent activation of the pro-survival protein Akt. R-Ras activation stimulates melanoma migration. Plexin C1 lowered R-Ras activity in melanoma and melanocytes, consistent with inhibitory effects of Plexin C1 on migration of melanocytes and melanoma. To determine if R-Ras is expressed in melanocytic lesions in vivo, staining of tissue microarrays of nevi and melanoma were performed. R-Ras expression was highly limited in melanocytic lesions, being essentially confined to primary melanoma, and almost completely absent in nevi and metastatic melanoma. These data suggest that loss of Plexin C1 in melanoma may promote early steps in melanoma progression through suppression of migration and proliferation, but pro-survival effects of Plexin C1 ultimately abrogate the tumor suppressive effects of Plexin C1. In primary melanoma, loss of Plexin C1 may function in early steps of melanoma progression by releasing inhibition of R-Ras activation, and stimulating migration. PMID:23160370

  6. The neural guidance receptor Plexin C1 delays melanoma progression.

    PubMed

    Chen, Y; Soong, J; Mohanty, S; Xu, L; Scott, G

    2013-10-10

    Plexin C1 is a type I transmembrane receptor with intrinsic R-Ras GTPase activity, which regulates cytoskeletal remodeling and adhesion in normal human melanocytes. Melanocytes are pigment-producing cells of the epidermis, precursors for melanoma, and express high levels of Plexin C1, which is lost in melanoma in vitro and in vivo. To determine if Plexin C1 is a tumor suppressor for melanoma, we introduced Plexin C1 into a primary human melanoma cell line, and phenotypes including migration, apoptosis, proliferation and tumor growth in mice were analyzed. Complimentary studies in which Plexin C1 was silenced in human melanocytes were performed. Plexin C1 significantly inhibited migration and proliferation in melanoma, whereas in melanocytes, loss of Plexin C1 increased migration and proliferation. In mouse xenografts, Plexin C1 delayed tumor growth of melanoma at early time points, but tumors eventually escaped the suppressive effects of Plexin C1, due to Plexin C1-dependent activation of the pro-survival protein Akt. R-Ras activation stimulates melanoma migration. Plexin C1 lowered R-Ras activity in melanoma and melanocytes, consistent with inhibitory effects of Plexin C1 on migration of melanocytes and melanoma. To determine if R-Ras is expressed in melanocytic lesions in vivo, staining of tissue microarrays of nevi and melanoma were performed. R-Ras expression was highly limited in melanocytic lesions, being essentially confined to primary melanoma, and almost completely absent in nevi and metastatic melanoma. These data suggest that loss of Plexin C1 in melanoma may promote early steps in melanoma progression through suppression of migration and proliferation, but pro-survival effects of Plexin C1 ultimately abrogate the tumor suppressive effects of Plexin C1. In primary melanoma, loss of Plexin C1 may function in early steps of melanoma progression by releasing inhibition of R-Ras activation, and stimulating migration.

  7. Horseshoe and entropy for C1 surface diffeomorphisms

    NASA Astrophysics Data System (ADS)

    Gan, Shaobo

    2002-05-01

    Let M be a two-dimensional closed Riemannian manifold and denote by Diff1(M) the set of C1 diffeomorphisms on M. Then, the C1 interior of {f in Diff1(M):h(f) = 0} is equal to the C1 interior of the closure of the Morse-Smale systems and equal to the C1 interior of the set of diffeomorphisms having no horseshoe.

  8. Nash equilibrium in differential games and the construction of the programmed iteration method

    SciTech Connect

    Averboukh, Yurii V

    2011-05-31

    This work is devoted to the study of nonzero-sum differential games. The set of payoffs in a situation of Nash equilibrium is examined. It is shown that the set of payoffs in a situation of Nash equilibrium coincides with the set of values of consistent functions which are fixed points of the program absorption operator. A condition for functions to be consistent is given in terms of the weak invariance of the graph of the functions under a certain differential inclusion. Bibliography: 18 titles.

  9. 26 CFR 1.682(c)-1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Definitions. 1.682(c)-1 Section 1.682(c)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Miscellaneous § 1.682(c)-1 Definitions. For definitions of the terms “husband” and “wife” as...

  10. New residential construction compliance: Evaluation of the Washington State Energy Code program

    SciTech Connect

    Warwick, W.M.; Lee, A.D.; Sandahl, L.J.; Durfee, D.L.; Richman, E.E.

    1993-07-01

    This report describes the Pacific Northwest Laboratory`s (PNL`s) evaluation of the Washington State Energy Code Program (WSECP). In 1990, the Washington State Legislature passed a residential energy efficiency code to be effective July 1, 1992. Bonneville supported passage and implementation of the code to ensure that new residences in the State of Washington were as energy efficient as economically feasible. The Washington State Energy Office (WSEO) is conducting the WSECP for Bonneville to support code implementation. This support takes several forms, including providing training to code enforcement officials, technical support both in the field and through telephone ``hot lines,`` and computerized tools to review house plans for code compliance. WSEO began implementing the WSECP in 1992, prior to the effective date of the new code. This first phase of the WSECP was the subject of an earlier process evaluation conducted by PNL. From that evaluation PNL found that most new homes being built immediately after the code went into effect were ``grand-fathered`` under the old code. The training program for the new code was in place and sessions were being attended by the jurisdictions but it was too early to determine if the training was effective in improving code compliance and easing the transition to the new energy code. That is the subject of this evaluation.

  11. Shuttle Rocket Motor Program: NASA should delay awarding some construction contracts. Report to the Chair, Subcommittee on Government Activities and Transportation, Committee on Government Operations, House of Representatives

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Even though the executive branch has proposed terminating the Advanced Solid Rocket Motor (ASRM) program, NASA is proceeding with all construction activity planned for FY 1992 to avoid schedule slippage if the program is reinstated by Congress. However, NASA could delay some construction activities for at least a few months without affecting the current launch data schedule. For example, NASA could delay Yellow Creek's motor storage and dock projects, Stennis' dock project, and Kennedy's rotation processing and surge facility and dock projects. Starting all construction activities as originally planned could result in unnecessarily incurring additional costs and termination liability if the funding for FY 1993 is not provided. If Congress decides to continue the program, construction could still be completed in time to avoid schedule slippage.

  12. Shuttle Rocket Motor Program: NASA should delay awarding some construction contracts. Report to the Chair, Subcommittee on Government Activities and Transportation, Committee on Government Operations, House of Representatives

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Even though the executive branch has proposed terminating the Advanced Solid Rocket Motor (ASRM) program, NASA is proceeding with all construction activity planned for FY 1992 to avoid schedule slippage if the program is reinstated by Congress. However, NASA could delay some construction activities for at least a few months without affecting the current launch data schedule. For example, NASA could delay Yellow Creek's motor storage and dock projects, Stennis' dock project, and Kennedy's rotation processing and surge facility and dock projects. Starting all construction activities as originally planned could result in unnecessarily incurring additional costs and termination liability if the funding for FY 1993 is not provided. If Congress decides to continue the program, construction could still be completed in time to avoid schedule slippage.

  13. C1q Deficiency and Neuropsychiatric Systemic Lupus Erythematosus.

    PubMed

    van Schaarenburg, Rosanne A; Magro-Checa, César; Bakker, Jaap A; Teng, Y K Onno; Bajema, Ingeborg M; Huizinga, Tom W; Steup-Beekman, Gerda M; Trouw, Leendert A

    2016-01-01

    C1q deficiency is a rare immunodeficiency, which is strongly associated with the development of systemic lupus erythematosus (SLE). A mutation in one of the C1q genes can either lead to complete deficiency or to low C1q levels with C1q polypeptide in the form of low-molecular weight (LMW) C1q. Patients with C1q deficiency mainly present with cutaneous and renal involvement. Although less frequent, neuropsychiatric (NP) involvement has also been reported in 20% of the C1q-deficient patients. This involvement appears to be absent in other deficiencies of early components of the complement classical pathway (CP) (C1r/C1s, C2, or C4 deficiencies). We describe a new case with C1q deficiency with a homozygous G34R mutation in C1qC-producing LMW-C1q presenting with a severe SLE flare with NP involvement. The serum of this patient contained very low levels of a LMW variant of C1q polypeptides. Cell lysates contained the three chains of C1q, but no intact C1q was detected, consistent with the hypothesis of the existence of a LMW-C1q. Furthermore, we provide a literature overview of NP-SLE in C1q deficiency and hypothesize about the potential role of C1q in the pathogenesis of NP involvement in these patients. The onset of NP-SLE in C1q-deficient individuals is more severe when compared with complement competent NP-SLE patients. An important number of cases present with seizures and the most frequent findings in neuroimaging are changes in basal ganglia and cerebral vasculitis. A defective CP, because of non-functional C1q, does not protect against NP involvement in SLE. The absence of C1q and, subsequently, some of its biological functions may be associated with more severe NP-SLE.

  14. C1q Deficiency and Neuropsychiatric Systemic Lupus Erythematosus

    PubMed Central

    van Schaarenburg, Rosanne A.; Magro-Checa, César; Bakker, Jaap A.; Teng, Y. K. Onno; Bajema, Ingeborg M.; Huizinga, Tom W.; Steup-Beekman, Gerda M.; Trouw, Leendert A.

    2016-01-01

    C1q deficiency is a rare immunodeficiency, which is strongly associated with the development of systemic lupus erythematosus (SLE). A mutation in one of the C1q genes can either lead to complete deficiency or to low C1q levels with C1q polypeptide in the form of low-molecular weight (LMW) C1q. Patients with C1q deficiency mainly present with cutaneous and renal involvement. Although less frequent, neuropsychiatric (NP) involvement has also been reported in 20% of the C1q-deficient patients. This involvement appears to be absent in other deficiencies of early components of the complement classical pathway (CP) (C1r/C1s, C2, or C4 deficiencies). We describe a new case with C1q deficiency with a homozygous G34R mutation in C1qC-producing LMW-C1q presenting with a severe SLE flare with NP involvement. The serum of this patient contained very low levels of a LMW variant of C1q polypeptides. Cell lysates contained the three chains of C1q, but no intact C1q was detected, consistent with the hypothesis of the existence of a LMW-C1q. Furthermore, we provide a literature overview of NP-SLE in C1q deficiency and hypothesize about the potential role of C1q in the pathogenesis of NP involvement in these patients. The onset of NP-SLE in C1q-deficient individuals is more severe when compared with complement competent NP-SLE patients. An important number of cases present with seizures and the most frequent findings in neuroimaging are changes in basal ganglia and cerebral vasculitis. A defective CP, because of non-functional C1q, does not protect against NP involvement in SLE. The absence of C1q and, subsequently, some of its biological functions may be associated with more severe NP-SLE. PMID:28082982

  15. Orthogonal polynomial Schauder bases in C[-1,1] with optimal growth of degrees

    SciTech Connect

    Skopina, M A

    2001-04-30

    For each {epsilon}>0 an orthogonal Schauder basis of algebraic polynomials P{sub n} in C[-1,1] is constructed such that the degrees of the polynomials have the estimate n(1+{epsilon}). This growth rate is the lowest possible.

  16. Construction and validation of two parent-report scales for the evaluation of early intervention programs.

    PubMed

    Fisher, William P; Elbaum, Batya; Coulter, W Alan

    2012-01-01

    The State Performance Plan (SPP) developed under the 2004 reauthorization of the Individuals with Disabilities Education Act (IDEA 2004, Public Law 108-446) requires states to collect data and report on the impact of early intervention services on three key outcomes for participating families. The NCSEAM Impact on Family Scale (NIFS) and the NCSEAM Family Centered Services Scale (NFCSS) were developed to provide states with a means to address this new reporting requirement and to collect additional data that would inform program improvement efforts. Items suggested by stakeholder groups were piloted with a nationally representative sample of parents of children with developmental delays or disabilities ages birth to three participating in early intervention services in eight states. The 28-item NIFS had measurement reliabilities ranging from .93-.96 in a sample of 1,750; measurement reliabilities for the 135-item NFCSS ranged from .94 to .97 in a sample of 1,755 respondents. A 29-item version of the NFCSS had measurement reliabilities ranging from .87 to .92. Using data from the pilot study, stakeholders established a recommended performance standard, set at a meaningful point in the NIFS item hierarchy, for each of the three established outcome areas.

  17. [Partnership between Psychosocial Care Center and Family Health Program: the challenge of a new knowledge construction].

    PubMed

    Delfini, Patrícia Santos de Souza; Sato, Miki Takao; Antoneli, Patrícia de Paulo; Guimarães, Paulo Octávio da Silva

    2009-10-01

    The objective of the article is to report an experience of partnership between a Psychosocial Care Center and three teams of the Family Health Program in the central region of São Paulo city. theoretical concepts like territory, subject, subjectivity/collective, receptiveness, bond, co-responsibility as well as the psychiatric and sanitary reform principles are the base and guide of this work. The partnership aims the promotion of mental health care based on articulated actions from different services. This way, the PSF's and mental health's workers are responsible for the demands of a territory. The strategies used in this partnership were meetings with both teams with training, case discussion about the families assisted, support to workers' difficulties and elaboration of therapeutical projects, and joint domiciliary visits. Some difficulties had been found during the research: great demand for health services and lack of institutional guidelines to guarantee the effectiveness of the partnership. The look directed to the family and the social context presents positive results compared to the look directed only to the illness. The partnership enriches the practice and a larger network of care in the territory becomes possible. It is necessary to bring up new proposals and innovative enterprises.

  18. Programming Self-Assembly of Tobacco Mosaic Virus Coat Proteins at Pickering Emulsion Interfaces for Nanorod-Constructed Capsules.

    PubMed

    Wang, Zhaocheng; Gao, Sijia; Liu, Xiangxiang; Tian, Ye; Wu, Man; Niu, Zhongwei

    2017-08-23

    Pickering emulsion constructions on nanorods with high aspect ratio are a great challenge because of the geometry restrictions. On the basis of the theory that the stability of Pickering emulsion is highly dependent on the size and amphiphilicity of the nanoparticle at fluid interfaces, we report a novel strategy to fabricate long-time stable Pickering emulsion consisting of tobacco mosaic virus (TMV)-like nanorods through the programming self-assembly of TMV coat protein (TMVCP). The first step is the self-assembly of amphiphilic TMVCP at Pickering emulsion interfaces, and the second step is the in situ interfacial self-assembly of TMVCP into nanorods with increased particle size. The robust capsules can be further fabricated through cross-linking of the proteins. By taking advantage of both the amphiphilicity of TMVCP and the subsequent size growth induced by TMVCP self-assembly, this work provides a powerful strategy for constructing robust capsules consisting of nanorods with high aspect ratio, which may show potential applications for drug delivery and virus recognition.

  19. Constructing vulnerabilty and protective measures indices for the enhanced critical infrastructure protection program.

    SciTech Connect

    Fisher, R. E.; Buehring, W. A.; Whitfield, R. G.; Bassett, G. W.; Dickinson, D. C.; Haffenden, R. A.; Klett, M. S.; Lawlor, M. A.; Decision and Information Sciences; LANL

    2009-10-14

    The US Department of Homeland Security (DHS) has directed its Protective Security Advisors (PSAs) to form partnerships with the owners and operators of assets most essential to the Nation's well being - a subclass of critical infrastructure and key resources (CIKR) - and to conduct site visits for these and other high-risk assets as part of the Enhanced Critical Infrastructure Protection (ECIP) Program. During each such visit, the PSA documents information about the facility's current CIKR protection posture and overall security awareness. The primary goals for ECIP site visits (DHS 2009) are to: (1) inform facility owners and operators of the importance of their facilities as an identified high-priority CIKR and the need to be vigilant in light of the ever-present threat of terrorism; (2) identify protective measures currently in place at these facilities, provide comparisons of CIKR protection postures across like assets, and track the implementation of new protective measures; and (3) enhance existing relationships among facility owners and operators; DHS; and various Federal, State, local tribal, and territorial partners. PSAs conduct ECIP visits to assess overall site security; educate facility owners and operators about security; help owners and operators identify gaps and potential improvements; and promote communication and information sharing among facility owners and operators, DHS, State governments, and other security partners. Information collected during ECIP visits is used to develop metrics; conduct sector-by-sector and cross-sector vulnerability comparisons; identify security gaps and trends across CIKR sectors and subsectors; establish sector baseline security survey results; and track progress toward improving CIKR security through activities, programs, outreach, and training (Snyder 2009). The data being collected are used in a framework consistent with the National Infrastructure Protection Plan (NIPP) risk criteria (DHS 2009). The NIPP

  20. Programming Constructs for Exascale Computing in Support of Space Situational Awareness

    NASA Astrophysics Data System (ADS)

    Schmalz, M.; Ranka, S.; Hayden, E.; Chapman, W.; Sahni, S.; Ritter, G.

    2013-09-01

    Increasing image and signal data burden associated with astronomical image processing in support of space situational awareness implies much-needed growth of computational throughput beyond petascale (1015 FLOP/s) to exascale regimes (1018 FLOP/s, 1018 bytes of memory, 1018 disks and Input/Output (I/O) channels, etc.) In addition to growth in applications data burden and diversity, the breadth and diversity of high performance computing architectures and their various organizations have confounded the development of a single, unifying, practicable model of parallel computation. Therefore, models for parallel Exa Scale processing have leveraged architectural and structural idiosyncrasies, yielding potential misapplications. In response to this challenge, we have developed a concise, efficient computational paradigm and software called Parallel Computing with Exascale Mapping (PCEM) to facilitate efficient mapping of annotated application codes to parallel exascale processors. Our theory, algorithms, software, and experimental results support annotation-based parallelization of application codes for envisioned exascale architectures, based on Image Algebra (IA) [Rit01]. Because of the rigor, completeness, conciseness, and layered design of image algebra notation, application-to-architecture mapping is feasible and scalable for exascale architectures. In particular, parallel operations and programs can be categorized in terms of six types of parallel operations - each type is mapped to heterogeneous exascale processors via simple rules in the PCEM annotation language. In this paper, we overview the opportunities and challenges of exascale computing for image and signal computing in support of astronomical image processing in space situational awareness applications. We discuss software interfaces and several demonstration applications, with performance analysis and results in terms of execution time as well as storage, power, and energy consumption for bus

  1. Role of C1q and C1q receptors in the pathogenesis of systemic lupus erythematosus.

    PubMed

    Ghebrehiwet, Berhane; Peerschke, Ellinor I

    2004-01-01

    The association between C1q and autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus (SLE) is well established. Deficiency in C1q is considered to be a strong susceptibility factor and is corroborated by the fact that > or = 92% of the known cases of hereditary deficiency in C1q develop rheumatic disease. Furthermore, the observation of the presence of high-affinity autoantibodies against C1q antibodies in patients with SLE provides a strong correlation between these antibodies and the inflammatory processes that occur in this disease. Recent evidence using C1q-deficient mice has shown the presence of glomerulonephritis with immune deposits and a large number of apoptotic bodies in the diseased glomeruli suggesting a defect in the clearance of apoptotic cell by macrophages and dendritic cells (DCs). Although these data are consistent with the hypothesis that C1q deficiency may induce a generalized failure to clear immune complexes and apoptotic cells, this concept alone cannot wholly explain why individuals with C1q deficiency are prone to develop SLE. Therefore, C1q alone or in conjunction with other surface molecules must play a much more fundamental role in immunoregulation, especially those processes that regulate T cell function and tolerance. In support of this hypothesis is the finding that C1q causes inhibition of mitrogen-induced T cell-proliferative response by interaction with C1q receptors. Furthermore, macrophages and possibly DCs not only synthesize but also display C1q as a type II cell surface molecule, especially at sites of inflammation. Although it is not yet known what role the surface-expressed C1q plays, it is tempting to assume that it plays a role in the priming of naïve T cells by DCs. This work will review the current concepts of the role of C1q and C1q receptors in autoimmunity.

  2. [Co-construction of a program to promote community participation among seniors living with psychosocial issues, with or without mental health problems].

    PubMed

    Parisien, Manon; Nour, Kareen; Belley, Anne-Marie; Aubin, Ginette; Billette, Véronique; Dallaire, Bernadette

    2017-01-01

    Objectives A significant proportion of Quebec seniors are living with mental health problems or psychosocial issues such as isolation, bereavement, and psychological distress. These people face many forms of exclusion and are likely to have limited social participation. This paper describes the co-construction steps of a program aimed at promoting community participation among this population.Methods A method for the co-construction of innovative practices in health promotion was used to develop a program that is relevant, rigorous and feasible in diverse settings. The process included several steps, notably: need analysis among seniors and practitioners, development of a logical model for the program, preparation of the leader's manual, validation of the manual by experts, and pilot testing of the program among groups of seniors.Results The goal of the Count me in! program is to promote utilization of the resources of the community that can provide seniors living with mental health conditions or psychosocial issues with activities and positive social contact. The intervention is based on the Strength Model. It includes an individual interview, an eight-meeting workshop, visits to community resources, and collective production of media communication.Conclusion A co-construction process allowed the program to be continuously adjusted in response to stakeholders' feedback. The most important lever for the co-construction was the reconciliation of the partners' practical, conceptual, and experiential expertise. However, contextual factors such as the organization and the availability of mental health services for seniors constituted important barriers to the process.

  3. Owlready: Ontology-oriented programming in Python with automatic classification and high level constructs for biomedical ontologies.

    PubMed

    Lamy, Jean-Baptiste

    2017-07-01

    Ontologies are widely used in the biomedical domain. While many tools exist for the edition, alignment or evaluation of ontologies, few solutions have been proposed for ontology programming interface, i.e. for accessing and modifying an ontology within a programming language. Existing query languages (such as SPARQL) and APIs (such as OWLAPI) are not as easy-to-use as object programming languages are. Moreover, they provide few solutions to difficulties encountered with biomedical ontologies. Our objective was to design a tool for accessing easily the entities of an OWL ontology, with high-level constructs helping with biomedical ontologies. From our experience on medical ontologies, we identified two difficulties: (1) many entities are represented by classes (rather than individuals), but the existing tools do not permit manipulating classes as easily as individuals, (2) ontologies rely on the open-world assumption, whereas the medical reasoning must consider only evidence-based medical knowledge as true. We designed a Python module for ontology-oriented programming. It allows access to the entities of an OWL ontology as if they were objects in the programming language. We propose a simple high-level syntax for managing classes and the associated "role-filler" constraints. We also propose an algorithm for performing local closed world reasoning in simple situations. We developed Owlready, a Python module for a high-level access to OWL ontologies. The paper describes the architecture and the syntax of the module version 2. It details how we integrated the OWL ontology model with the Python object model. The paper provides examples based on Gene Ontology (GO). We also demonstrate the interest of Owlready in a use case focused on the automatic comparison of the contraindications of several drugs. This use case illustrates the use of the specific syntax proposed for manipulating classes and for performing local closed world reasoning. Owlready has been successfully

  4. Hereditary angioedema with normal C1-INH (HAE type III).

    PubMed

    Riedl, Marc A

    2013-01-01

    Hereditary angioedema (HAE) with normal C1 inhibitor (C1-INH), also known as HAE type III, is a familial condition only clinically recognized within the past three decades. Similar to HAE from C1-INH deficiency (HAE types I and II), affected individuals experience unpredictable angioedema episodes of the skin, gastrointestinal tract, and airway. Unique clinical features of HAE with normal C1-INH include the predominance of affected women, frequent exacerbation by estrogen, and a prominence of angioedema that involves the face and oropharynx. The underlying pathophysiology of HAE with normal C1-INH is poorly understood, but indirect evidence points to contact pathway dysregulation with bradykinin-mediated angioedema. Currently, evaluation is complicated by a lack of confirmatory laboratory testing such that clinical criteria must often be used to make the diagnosis of HAE with normal C1-INH. Factor XII mutations have been identified in only a minority of persons affected by HAE with normal C1-INH, limiting the utility of such analysis. To date, no controlled clinical studies have examined the efficacy of therapeutic agents for HAE with normal C1-INH, although published evidence supports frequent clinical benefit with medications shown effective in HAE due to C1-INH deficiency.

  5. Some properties of the sum C1(h, k)

    NASA Astrophysics Data System (ADS)

    Cetin, Elif

    2017-07-01

    In [10], we have investigated properties of the sum C1(h, k). In this paper, we will give some other arithmetic properties of the sum C1(h, k). Moreover, in the light of the sum B1(h, k), which has also defined in [10], we will give specific values of the sum C1(h, k) when h + k is an odd number. Finally, we will give a relation between the sum C1(h, k) and the Hardy-Berndt sum s5(h, k) for a special case.

  6. Development Scaffolding for Construction of Evaluation Instrument Training Program on The Cognitive Domain For Senior High School Physics Teachers and The Same Level

    NASA Astrophysics Data System (ADS)

    Arif, W.; Suhandi, A.; Kaniawati, I.; Setiawan, A.

    2017-02-01

    The development of scaffolding for evaluation instrument construction training program on the cognitive domain for senior high school physics teacher and the same level that is specified in the test instrument has been done. This development was motivated by the low ability of the majority of physics teachers in constructing the physics learning achievement test. This situation not in accordance with the demands of Permendiknas RI no. 16 tahun 2007 concerning the standard of academic qualifications and competence of teachers, stating that teachers should have a good ability to develop instruments for assessment and evaluation of process and learning outcomes. Based on the preliminary study results, it can be seen that the main cause of the inability of teachers in developing physics achievement test is because they do not good understand of the indicators for each aspect of cognitive domains. Scaffolding development is done by using the research and development methods formulated by Thiagarajan which includes define, design and develope steps. Develop step includes build the scaffolding, validation of scaffolding by experts and the limited pilot implementations on the training activities. From the build scaffolding step, resulted the scaffolding for the construction of test instruments training program which include the process steps; description of indicators, operationalization of indicators, construction the itemsframework (items scenarios), construction the items stem, construction the items and checking the items. The results of the validation by three validator indicates that the built scaffolding are suitable for use in the construction of physics achievement test training program, especially for novice. The limited pilot implementation of the built scaffolding conducted in training activities attended by 10 senior high school physics teachers in Garut district. The results of the limited pilot implementation shows that the built scaffolding have a medium

  7. Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation

    PubMed Central

    Deng, Liehua; Yang, Hengwen; Zhu, Leqing; Wang, Xiao; Edwards, Michael G.; Richers, Brittany; Leung, Donald Y. M.

    2016-01-01

    The epidermis serves as a critical protective barrier between the internal and external environment of the human body. Its remarkable barrier function is established through the keratinocyte (KC) terminal differentiation program. The transcription factors specifically regulating terminal differentiation remain largely unknown. Using a RNA-sequencing (RNA-seq) profiling approach, we found that forkhead box c 1 (FOXC1) was significantly up-regulated in human normal primary KC during the course of differentiation. This observation was validated in human normal primary KC from several different donors and human skin biopsies. Silencing FOXC1 in human normal primary KC undergoing differentiation led to significant down-regulation of late terminal differentiation genes markers including epidermal differentiation complex genes, keratinization genes, sphingolipid/ceramide metabolic process genes and epidermal specific cell-cell adhesion genes. We further demonstrated that FOXC1 works down-stream of ZNF750 and KLF4, and upstream of GRHL3. Thus, this study defines FOXC1 as a regulator specific for KC terminal differentiation and establishes its potential position in the genetic regulatory network. PMID:27907090

  8. Florida Radon Research Program: Technical support for the development of radon-resistant construction standards. Rept. for Aug-Sep 91

    SciTech Connect

    Sanchez, D.C.; Dixon, R.; Madani, M.

    1991-01-01

    The paper describes the technical direction of the Florida Radon Research Program (FRRP), its current objectives, and accomplishments to date. The 1988 Florida Legislature mandated the development of standards for the construction of radon resistant buildings. A program of research and development was initiated involving the Florida State University System, the Florida Department of Community Affairs, and the U.S. EPA. The FRRP will complete two years of concentrated effort to develop, test, and demonstrate a sound technical basis for radon resistant construction standards.

  9. 26 CFR 1.652(c)-1 - Different taxable years.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Different taxable years. 1.652(c)-1 Section 1... (CONTINUED) INCOME TAXES Trusts Which Distribute Current Income Only § 1.652(c)-1 Different taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable year...

  10. Anti-C1q in systemic lupus erythematosus.

    PubMed

    Stojan, G; Petri, M

    2016-07-01

    C1q is the first component of the classical complement pathway. Both clinically validated in-house ELISA assays as well as commercial ELISA kits are used for detection of anti-C1q antibodies. Anti-C1q autoantibodies can be detected in a wide range of autoimmune diseases and are highly sensitive for hypocomplementemic uticarial vasculitis. In SLE, anti-C1q are strongly associated with proliferative lupus nephritis, and their absence carries a negative predictive value for development of lupus nephritis of close to 100%. Anti-C1q in combination with anti-dsDNA and low complement has the strongest serological association with renal involvement. The anti-C1q titers correlate with global disease activity scores in patients with renal involvement, and higher titers seem to precede renal flares. After the successful treatment of a renal flare, anti-C1q has the tendency to decrease or even become undetectable. The main obstacle to the inclusion of anti-C1q in the classification criteria and clinical management of SLE is the lack of standardized laboratory assays.

  11. Missed C1 posterior arch fracture: a case report

    PubMed Central

    Munro, Donald S

    1990-01-01

    A case of a C1 posterior arch fracture following a fall is presented. The need to perform a thorough history and examination, regardless of previous examination findings, is emphasized. This is especially true when there is a history of recent trauma. A brief discussion of the characteristics and management of C1 fractures follows. ImagesFigure 1Figure 2Figure 3

  12. 26 CFR 1.678(c)-1 - Trusts for support.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Trusts for support. 1.678(c)-1 Section 1.678(c... (CONTINUED) INCOME TAXES Grantors and Others Treated As Substantial Owners § 1.678(c)-1 Trusts for support... cotrustee, to apply the income of the trust to the support or maintenance of a person whom the holder...

  13. 26 CFR 1.1092(c)-1 - Qualified covered calls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Qualified covered calls. 1.1092(c)-1 Section 1... (CONTINUED) INCOME TAXES Wash Sales of Stock Or Securities § 1.1092(c)-1 Qualified covered calls. (a) In...), however, writing a qualified covered call option and owning the optioned stock is not treated as...

  14. Sharpness for C1 linearization of planar hyperbolic diffeomorphisms

    NASA Astrophysics Data System (ADS)

    Zhang, Wenmeng; Zhang, Weinian

    2014-12-01

    C1 linearization preserves smooth dynamical behaviors and distinguishes qualitative properties in characteristic directions. Planar hyperbolic diffeomorphisms are the most elementary ones of representatively technical difficulties in the study of C1 linearization. In the Poincaré domain (both eigenvalues inside the unit circle S1) a lower bound α0 was given such that C smoothness with α0<α≤1 admits C1 linearization. Our first purpose of this paper is to prove the sharpness of α0 and give a weaker linearization for α≤α0. In the Siegel domain (one eigenvalue inside S1 but the other outside S1) it is known that C smoothness admits C1 linearization for all α∈(0,1]. The second purpose is to prove that the C1 linearization is actually a C linearization and give sharp estimates for β.

  15. Modeling of constructed wetland performance in BOD5 removal for domestic wastewater under changes in relative humidity using genetic programming.

    PubMed

    Sankararajan, Vanitha; Neelakandhan, Nampoothiri; Chandrasekaran, Sivapragasam

    2017-04-01

    Despite the extensive use of constructed wetland (CW) as an effective method for domestic wastewater treatment, there is lack of clarity in arriving at well-defined design guidelines. This is particularly due to the fact that the design of CW is dependent on many inter-connected parameters which interact in a complex manner. Consequently, different researchers in the past have tried to address different aspects of this complexity. In this study, an attempt is made to model the influence of relative humidity (RH) in the effectiveness of BOD5 removal. Since it is an accepted fact that plants respond to change in humidity, it is necessary to take this parameter into consideration particularly when the CW is to be designed involving changes in relative humidity over a shorter time horizon (say a couple of months). This study reveals that BOD5out depends on the ratio of BOD5in and relative humidity. An attempt is also made to model the outlet BOD5 using genetic programming with inlet BOD5 and relative humidity as input parameters.

  16. The South Carolina Program for Library Development, 1983-1988, under the Library Services and Construction Act (P.L. 95-123, FY 1983).

    ERIC Educational Resources Information Center

    South Carolina State Library, Columbia.

    Prepared as an outline of the long range South Carolina library development program required by the Library Services and Construction Act (LSCA), this document describes: (1) the library public, with emphasis on disadvantaged, blind, physically handicapped, elderly, and institutionalized persons as well as persons with limited English speaking…

  17. Engagement in a Community of Learners as a Mediating Agent toward the Construction of Technological Pedagogical Content Knowledge (TPACK) in an Online Master's Program

    ERIC Educational Resources Information Center

    Gillow-Wiles, Henry

    2012-01-01

    This study investigates how teachers develop and extend their understanding and knowledge of teaching and learning with digital technologies in a primarily online Master of Science program. The investigation focuses on exploring the relationship between developing an online community of learners and the construction of technological pedagogical…

  18. Engagement in a Community of Learners as a Mediating Agent toward the Construction of Technological Pedagogical Content Knowledge (TPACK) in an Online Master's Program

    ERIC Educational Resources Information Center

    Gillow-Wiles, Henry

    2012-01-01

    This study investigates how teachers develop and extend their understanding and knowledge of teaching and learning with digital technologies in a primarily online Master of Science program. The investigation focuses on exploring the relationship between developing an online community of learners and the construction of technological pedagogical…

  19. Self-Help Construction of 1-Story Buildings. Appropriate Technologies for Development. Program & Training Journal Manual Series, Number 6.

    ERIC Educational Resources Information Center

    Gallant, Peter

    This manual is designed to assist Peace Corps field workers who have little or no construction experience in helping communities or families to construct one-story buildings. Discussed in a chapter on basic planning and design are site and position; size, shape, and floor plan; and construction materials. The next chapter is a detailed examination…

  20. Periodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S, which Encode Subcomponents C1r and C1s of Complement.

    PubMed

    Kapferer-Seebacher, Ines; Pepin, Melanie; Werner, Roland; Aitman, Timothy J; Nordgren, Ann; Stoiber, Heribert; Thielens, Nicole; Gaboriaud, Christine; Amberger, Albert; Schossig, Anna; Gruber, Robert; Giunta, Cecilia; Bamshad, Michael; Björck, Erik; Chen, Christina; Chitayat, David; Dorschner, Michael; Schmitt-Egenolf, Marcus; Hale, Christopher J; Hanna, David; Hennies, Hans Christian; Heiss-Kisielewsky, Irene; Lindstrand, Anna; Lundberg, Pernilla; Mitchell, Anna L; Nickerson, Deborah A; Reinstein, Eyal; Rohrbach, Marianne; Romani, Nikolaus; Schmuth, Matthias; Silver, Rachel; Taylan, Fulya; Vandersteen, Anthony; Vandrovcova, Jana; Weerakkody, Ruwan; Yang, Margaret; Pope, F Michael; Byers, Peter H; Zschocke, Johannes

    2016-11-03

    Periodontal Ehlers-Danlos syndrome (pEDS) is an autosomal-dominant disorder characterized by early-onset periodontitis leading to premature loss of teeth, joint hypermobility, and mild skin findings. A locus was mapped to an approximately 5.8 Mb region at 12p13.1 but no candidate gene was identified. In an international consortium we recruited 19 independent families comprising 107 individuals with pEDS to identify the locus, characterize the clinical details in those with defined genetic causes, and try to understand the physiological basis of the condition. In 17 of these families, we identified heterozygous missense or in-frame insertion/deletion mutations in C1R (15 families) or C1S (2 families), contiguous genes in the mapped locus that encode subunits C1r and C1s of the first component of the classical complement pathway. These two proteins form a heterotetramer that then combines with six C1q subunits. Pathogenic variants involve the subunit interfaces or inter-domain hinges of C1r and C1s and are associated with intracellular retention and mild endoplasmic reticulum enlargement. Clinical features of affected individuals in these families include rapidly progressing periodontitis with onset in the teens or childhood, a previously unrecognized lack of attached gingiva, pretibial hyperpigmentation, skin and vascular fragility, easy bruising, and variable musculoskeletal symptoms. Our findings open a connection between the inflammatory classical complement pathway and connective tissue homeostasis.

  1. Modified C1 lateral mass screw insertion using a high entry point to avoid postoperative occipital neuralgia.

    PubMed

    Lee, Sun-Ho; Kim, Eun-Sang; Eoh, Whan

    2013-01-01

    For the past decade, a screw-rod construct has been used commonly to stabilize the atlantoaxial joint, but the insertion of the screw through the C1 lateral mass (LM) can cause several complications. We evaluated whether using a higher screw entry point for C1 lateral mass (LM) fixation than in the standard procedure could prevent screw-induced occipital neuralgia. We enrolled 12 consecutive patients who underwent bilateral C1 LM fixation, with the modified screw insertion point at the junction of the C1 posterior arch and the midpoint of the posterior inferior portion of the C1 LM. We measured postoperative clinical and radiological parameters and recorded intraoperative complications, postoperative neurological deficits and the occurrence of occipital neuralgia. Postoperative plain radiographs were used to check for malpositioning of the screw or failure of the construct. Four patients underwent atlantoaxial stabilization for a transverse ligament injury or a C1 or C2 fracture, six patients for os odontoideum, and two patients for C2 metastasis. No patient experienced vertebral artery injury or cerebrospinal fluid leak, and all had minimal blood loss. No patient suffered significant occipital neuralgia, although one patient developed mild, transient unilateral neuralgia. There was also no radiographic evidence of construct failure. Twenty screws were positioned correctly through the intended entry points, but three screws were placed inferiorly (that is, below the arch), and one screw was inserted too medially. When performing C1-C2 fixation using the standard (Harms) construct, surgeons should be aware of the possible development of occipital neuralgia. A higher entry point may prevent this complication; therefore, we recommend that the screw should be inserted into the arch of C1 if it can be accommodated. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. Report to the Board of Regents State University System of Florida. Review of Programs: Architecture, Architectural Technology, Landscape Architecture, Interior Design, Construction and Construction Technology, Building Construction, Urban and Regional Planning.

    ERIC Educational Resources Information Center

    McMinn, William G.

    An evaluation and report was done on the status of programs in architecture and related fields in the Florida State University System as a follow-up to a 1983 evaluation. The evaluation involved self-studies prepared by each program and a series of site visits to each of seven campuses and two centers with programs under review. These institutions…

  3. Cbln and C1q family proteins: new transneuronal cytokines.

    PubMed

    Yuzaki, M

    2008-06-01

    The C1q family is characterized by a C-terminal conserved global C1q domain, which is structurally very similar to the tumor necrosis factor homology domain. Although some C1q family members are expressed in the central nervous system, their functions have not been well characterized. Cbln1, a member of the Cbln subfamily of the C1q family, is predominantly expressed in cerebellar granule cells. Interestingly, Cbln1 was recently shown to play two unique roles at excitatory synapses formed between cerebellar granule cells and Purkinje cells: the formation and stabilization of synaptic contact, and the control of functional synaptic plasticity by regulating the postsynaptic endocytosis pathway. Since other Cbln subfamily members, Cbln2-Cbln4, are expressed in various regions of developing and mature brains, Cbln subfamily proteins may generally serve as a new class of transneuronal regulators of synapse development and synaptic plasticity in various brain regions.

  4. Effectiveness of the training program for workers at construction sites of the high-speed railway line between Torino and Novara: impact on injury rates.

    PubMed

    Bena, A; Berchialla, P; Coffano, M E; Debernardi, M L; Icardi, L G

    2009-12-01

    There are very few published studies evaluating the impact of safety and health training on injury outcomes in the construction industry. The aim of this study was to assess the impact of the training program on injury rates at a major railway construction project. The population consisted of 2,795 workers involved in a safety training program at the construction sites of the high-speed railway line Torino-Novara. Two types of analyses were carried out in order to assess the effectiveness of the training program in reducing the number of injuries: (i) a pre-post analysis, which took into account the fact that workers were enrolled at different times and the training intervention did not occur at the same time for all subjects; (ii) an interrupted time-series model, which corrected for the time trend and considered the autocorrelation between individual observations. Twenty-nine percent of workers who spent at least 1 day at the construction sites attended at least one training module. Pre-post analysis: At the end of the training program, the incidence of occupational injuries had fallen by 16% after the basic training module and by 25% following the specific modules. Time-series model: Training led to a 6% reduction in injury rates, which was not statistically significant. The training program that was implemented had a moderately positive impact on the health of workers. Further studies are being conducted to obtain a more complete assessment of the actual effectiveness of the program in reducing the incidence of injuries. Copyright 2009 Wiley-Liss, Inc.

  5. Anti-C1q antibodies in systemic lupus erythematosus.

    PubMed

    Orbai, A-M; Truedsson, L; Sturfelt, G; Nived, O; Fang, H; Alarcón, G S; Gordon, C; Merrill, Jt; Fortin, P R; Bruce, I N; Isenberg, D A; Wallace, D J; Ramsey-Goldman, R; Bae, S-C; Hanly, J G; Sanchez-Guerrero, J; Clarke, A E; Aranow, C B; Manzi, S; Urowitz, M B; Gladman, D D; Kalunian, K C; Costner, M I; Werth, V P; Zoma, A; Bernatsky, S; Ruiz-Irastorza, G; Khamashta, M A; Jacobsen, S; Buyon, J P; Maddison, P; Dooley, M A; Van Vollenhoven, R F; Ginzler, E; Stoll, T; Peschken, C; Jorizzo, J L; Callen, J P; Lim, S S; Fessler, B J; Inanc, M; Kamen, D L; Rahman, A; Steinsson, K; Franks, A G; Sigler, L; Hameed, S; Pham, N; Brey, R; Weisman, M H; McGwin, G; Magder, L S; Petri, M

    2015-01-01

    Anti-C1q has been associated with systemic lupus erythematosus (SLE) and lupus nephritis in previous studies. We studied anti-C1q specificity for SLE (vs rheumatic disease controls) and the association with SLE manifestations in an international multicenter study. Information and blood samples were obtained in a cross-sectional study from patients with SLE (n = 308) and other rheumatologic diseases (n = 389) from 25 clinical sites (84% female, 68% Caucasian, 17% African descent, 8% Asian, 7% other). IgG anti-C1q against the collagen-like region was measured by ELISA. Prevalence of anti-C1q was 28% (86/308) in patients with SLE and 13% (49/389) in controls (OR = 2.7, 95% CI: 1.8-4, p < 0.001). Anti-C1q was associated with proteinuria (OR = 3.0, 95% CI: 1.7-5.1, p < 0.001), red cell casts (OR = 2.6, 95% CI: 1.2-5.4, p = 0.015), anti-dsDNA (OR = 3.4, 95% CI: 1.9-6.1, p < 0.001) and anti-Smith (OR = 2.8, 95% CI: 1.5-5.0, p = 0.01). Anti-C1q was independently associated with renal involvement after adjustment for demographics, ANA, anti-dsDNA and low complement (OR = 2.3, 95% CI: 1.3-4.2, p < 0.01). Simultaneously positive anti-C1q, anti-dsDNA and low complement was strongly associated with renal involvement (OR = 14.9, 95% CI: 5.8-38.4, p < 0.01). Anti-C1q was more common in patients with SLE and those of Asian race/ethnicity. We confirmed a significant association of anti-C1q with renal involvement, independent of demographics and other serologies. Anti-C1q in combination with anti-dsDNA and low complement was the strongest serological association with renal involvement. These data support the usefulness of anti-C1q in SLE, especially in lupus nephritis. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  6. Anti-C1q Antibodies in Systemic Lupus Erythematosus

    PubMed Central

    ORBAI, ANA-MARIA; TRUEDSSON, LENNART; STURFELT, GUNNAR; NIVED, OLA; FANG, HONG; ALARCÓN, GRACIELA S.; GORDON, CAROLINE; MERRILL, JOAN T.; FORTIN, PAUL R.; BRUCE, IAN N.; ISENBERG, DAVID A.; WALLACE, DANIEL J.; RAMSEY-GOLDMAN, ROSALIND; BAE, SANG-CHEOL; HANLY, JOHN G.; SANCHEZ-GUERRERO, JORGE; CLARKE, ANN E.; ARANOW, CYNTHIA B.; MANZI, SUSAN; UROWITZ, MURRAY B.; GLADMAN, DAFNA D.; KALUNIAN, KENNETH C.; COSTNER, MELISSA I.; WERTH, VICTORIA P.; ZOMA, ASAD; BERNATSKY, SASHA; RUIZ-IRASTORZA, GUILLERMO; KHAMASHTA, MUNTHER A.; JACOBSEN, SOREN; BUYON, JILL P.; MADDISON, PETER; DOOLEY, MARY ANNE; VAN VOLLENHOVEN, RONALD F.; GINZLER, ELLEN; STOLL, THOMAS; PESCHKEN, CHRISTINE; JORIZZO, JOSEPH L.; CALLEN, JEFFREY P.; LIM, S. SAM; FESSLER, BARRI J.; INANC, MURAT; KAMEN, DIANE L.; RAHMAN, ANISUR; STEINSSON, KRISTJAN; FRANKS, ANDREW G.; SIGLER, LISA; HAMEED, SUHAIL; PHAM, NEENA; BREY, ROBIN; WEISMAN, MICHAEL H.; MCGWIN, GERALD; MAGDER, LAURENCE S.; PETRI, MICHELLE

    2014-01-01

    Objective Anti-C1q has been associated with systemic lupus erythematosus (SLE) and lupus nephritis in previous studies. We studied anti-C1q specificity for SLE (vs. rheumatic disease controls) and the association with SLE manifestations in an international multi-center study. Methods Information and blood samples were obtained in a cross-sectional study from patients with SLE (n=308) and other rheumatologic diseases (n=389) from 25 clinical sites (84% female, 68% Caucasian, 17% African descent, 8% Asian, 7% other). IgG anti-C1q against the collagen-like region was measured by ELISA. Results Prevalence of anti-C1q was 28% (86/308) in patients with SLE and 13% (49/389) in controls (OR=2.7, 95% CI: 1.8-4, p<0.001). Anti-C1q was associated with proteinuria (OR=3.0, 95% CI: 1.7-5.1, p<0.001), red cell casts (OR=2.6, 95% CI: 1.2-5.4, p=0.015), anti-dsDNA (OR=3.4, 95% CI: 1.9-6.1, p<0.001) and anti-Smith (OR=2.8, 95% CI: 1.5-5.0, p=0.01). Anti-C1q was independently associated with renal involvement after adjustment for demographics, ANA, anti-dsDNA and low complement (OR=2.3, 95% CI: 1.3-4.2, p<0.01). Simultaneously positive anti-C1q, anti-dsDNA and low complement was strongly associated with renal involvement (OR=14.9, 95% CI: 5.8-38.4, p<0.01). Conclusions Anti-C1q was more common in patients with SLE and those of Asian race/ethnicity. We confirmed a significant association of anti-C1q with renal involvement, independent of demographics and other serologies. Anti-C1q in combination with anti-dsDNA and low complement was the strongest serological association with renal involvement. These data support the usefulness of anti-C1q in SLE, especially in lupus nephritis. PMID:25124676

  7. Hagfish C1q: its unique binding property.

    PubMed

    Yamaguchi, Tomokazu; Takamune, Kazufumi; Kondo, Masakazu; Takahashi, Yukinori; Kato-Unoki, Yoko; Nakao, Miki; Sano, Naomi; Fujii, Tamotsu

    2014-03-01

    Hagfish C1q (HaC1q) was identified and characterized as a pattern-recognition molecule (PRM) in the hagfish complement system. The serum from hagfish, Eptatretus burgeri, was applied to a GlcNAc-agarose column and eluted sequentially with GlcNAc and EDTA. Four (31, 27, 26, and 19 kDa) and one (26 kDa) proteins were detected as bound molecules in the GlcNAc- and the EDTA-eluates, respectively. Among these, the 26 kDa protein from the EDTA eluate was found to be a homologue of mammalian C1q through cDNA analysis. HaC1q had an ability to bind to various microbes in a Ca(2+)-dependent manner and its target ligands on the microbes were lipopolysaccharide, lipoteichoic acid, and peptidoglycan. The binding of HaC1q to GlcNAc-agarose was not inhibited by an excess amount of monosaccharide such as GlcNAc. While HaC1q bound to Sepharose 6B with a matrix of GlcNAc-agarose (polymer of agarobiose), it did not bind to Sepharose 4B that contained lower concentration of agarobiose than Sepharose 6B. Therefore, the target of HaC1q on GlcNAc-agarose was concluded to be agarobiose and high density of the target moiety seemed to be required for the stable binding. This finding was in accordance with the known behavior of other lectins involved in the complement system. We have concluded that HaC1q recognizes agarobiose-like structures present on the surface of microbes and acts as a pattern-recognition molecule in the process for elimination of invading microbes. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Expression of staphylococcal enterotoxin C1 in Escherichia coli.

    PubMed Central

    Bohach, G A; Schlievert, P M

    1987-01-01

    The structural gene encoding staphylococcal enterotoxin C1 was cloned into Escherichia coli and localized on a 1.5-kilobase HindIII-ClaI DNA fragment by subcloning. The toxin was partially purified from E. coli clones and shown to be immunologically identical to enterotoxin C1 from Staphylococcus aureus. The cloned toxin also had the same molecular weight (26,000) and charge heterogeneity as staphylococcus-derived enterotoxin. Toxins from both sources were equally biologically active. Images PMID:3542834

  9. Vein formation in the C1 carbonaceous chondrites

    NASA Technical Reports Server (NTRS)

    Richardson, S. M.

    1978-01-01

    Veins in the C1 chondrites Orgueil, Alais, and Ivuna have been deposited during an extended period of impact brecciation and leaching. At least three generations of mineralization, dominated successively by carbonates, calcium sulfate, and magnesium sulfate, can be recognized. Vein minerals are derived locally by closed-system reactions between matrix phyllosilicates and an aqueous fluid, with the result that few, if any, primitive mineral phases still exist in the C1s.

  10. 26 CFR 1.1402(c)-1 - Trade or business.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 12 2010-04-01 2010-04-01 false Trade or business. 1.1402(c)-1 Section 1.1402(c... (CONTINUED) INCOME TAXES Tax on Self-Employment Income § 1.1402(c)-1 Trade or business. In order for an individual to have net earnings from self-employment, he must carry on a trade or business, either as an...

  11. 26 CFR 1.1402(c)-1 - Trade or business.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 12 2013-04-01 2013-04-01 false Trade or business. 1.1402(c)-1 Section 1.1402(c... (CONTINUED) INCOME TAXES (CONTINUED) Tax on Self-Employment Income § 1.1402(c)-1 Trade or business. In order for an individual to have net earnings from self-employment, he must carry on a trade or business...

  12. 26 CFR 1.1402(c)-1 - Trade or business.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 12 2012-04-01 2012-04-01 false Trade or business. 1.1402(c)-1 Section 1.1402(c... (CONTINUED) INCOME TAXES (CONTINUED) Tax on Self-Employment Income § 1.1402(c)-1 Trade or business. In order for an individual to have net earnings from self-employment, he must carry on a trade or business...

  13. Biomechanical Evaluation of a Novel Integrated C1 Laminar Hook Combined with C1-C2 Transarticular Screws for Atlantoaxial Fusion: An In Vitro Human Cadaveric Study.

    PubMed

    Xu, Tianming; Guo, Qunfeng; Liu, Qi; Zhang, Peng; Lu, Ming; Lu, Xuhua; Chen, Fei; Guo, Xiang; Ni, Bin

    2016-08-01

    To evaluate the acute stability of a novel integrated C1 laminar hook (H) combined with a C1-C2 transarticular screw (TAS) with established techniques. A novel integrated C1 laminar hook was tested. Seven human cadaveric cervical spines (C0-C3) were used. The range of motion (ROM) of C1-C2 during flexion-extension, lateral bending, and axial rotation were recorded. The specimens were tested under the following conditions: intact, destabilized (using a type II odontoid fracture model), and destabilized but with internal fixation. The following screw systems were used: bilateral C1-C2 TAS combined with the Gallie (G) technique (TAS+G), C1-C2 TAS combined with a novel integrated C1 laminar hook (TAS+H), C1 lateral mass screw and C2 pedicle screws (C2PS+C1LMS), and novel integrated C1 laminar hook combined with C2 pedicle screws (C2PS+H). The TASs were always inserted after the C2PSs. The C2PS+C1LMS and C2PS+H tests were performed alternatively, as were the TAS+G and TAS+H tests. All fixation constructs greatly improved acute atlantoaxial stability, with no significant difference among TAS+H, TAS+G, and C2PS+C1LMS (all P > 0.05). C2PS+H showed the greatest C1-C2 ROM in axial rotation, significantly different from TAS+G, C2PS+C1LMS, and TAS+H fixation models (all P < 0.05). However, there were no significant differences between C2PS+H and the other 3 models in flexion-extension and lateral bending (all P > 0.05). The TAS+H technique can achieve acute stability comparable to that with the TAS+G technique for treating C1-C2 instability. The C2PS+H is a promising alternative, although it provides less stability in axial rotation than TAS+G, TAS+H, or C2PS+C1LMS. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Participatory Training to Improve Safety and Health in Small Construction Sites in Some Countries in Asia: Development and Application of the WISCON Training Program.

    PubMed

    Kawakami, Tsuyoshi

    2016-08-01

    A participatory training program, Work Improvement in Small Construction Sites, was developed to provide practical support measures to the small construction sector. Managers and workers from selected small sites were interviewed about their occupational safety and health risks. The Work Improvement in Small Construction Sites training program comprised a 45-item action checklist, photos, and illustrations showing local examples and group work methods. Pilot training workshops were carried out with workers and employers in Cambodia, Laos, Mongolia, Thailand, and Vietnam. Participants subsequently planned, and using locally available low-cost materials, implemented their own improvements such as hand-made hand trucks to carry heavy materials, removal of projecting nails from timber materials, and fences to protect roof workers from falling. Local Work Improvement in Small Construction Sites trainers consisting of government officials, workers, employers, and nongovernment organization representatives were then trained to implement the Work Improvement in Small Construction Sites training widely. Keys to success were easy-to-apply training tools aiming at immediate, low-cost improvements, and collaboration with various local people's networks. © The Author(s) 2016.

  15. Army National Guard. FY 1994 Budget Estimates, April 1993. Military Construction Program, FY 1994. Justification Data Submission to Congress.

    DTIC Science & Technology

    1993-04-01

    construction. xii FY 1994 GUARD AND RESERVE 2. DATE ARNG MILITARY CONSTRUCTION 3. INSTALLATION AND LOCATION 4. AREA CONSTRCOST INDEX EGLIN AIR FORCE BASE...DATE FY 1994 GUARD AND RESERVE 2 ,pI4Q MILITARY CONSTRUCTION 3. INSTALLATION AND LOCATION EGLIN AIR FORCE BASE (FLORIDA), ALABAMA i1. PERSONNU STRENGTH...AUTHORIZED ACTUAL N/A 14. OUTSTANDING POLLUTION AND SAFETY DEFICIENCIES (0000) A. AIR POLLUTION NONE B. WATER POLLUTION NONE C. OCCUPATIONAL SAFETY AND

  16. Uncoupling complement C1s activation from C1q binding in apoptotic cell phagocytosis and immunosuppressive capacity.

    PubMed

    Colonna, Lucrezia; Parry, Graham C; Panicker, Sandip; Elkon, Keith B

    2016-02-01

    Complement activation contributes to inflammation in many diseases, yet it also supports physiologic apoptotic cells (AC) clearance and its downstream immunosuppressive effects. The roles of individual complement components in AC phagocytosis have been difficult to dissect with artificially depleted sera. Using human in vitro systems and the novel antibody complement C1s inhibitor TNT003, we uncoupled the role of the enzymatic activation of the classical pathway from the opsonizing role of C1q in mediating a) the phagocytosis of early and late AC, and b) the immunosuppressive capacity of early AC. We found that C1s inhibition had a small impact on the physiologic clearance of early AC, leaving their immunosuppressive properties entirely unaffected, while mainly inhibiting the phagocytosis of late apoptotic/secondary necrotic cells. Our data suggest that C1s inhibition may represent a valuable therapeutic strategy to control classical pathway activation without causing significant AC accumulation in diseases without defects in AC phagocytosis.

  17. Pilot program to evaluate the effectiveness of OSHA (occupational safety and health act) construction standards at the point of erection. Final report

    SciTech Connect

    Pals, J.; Kane, J.; Marcello, J.

    1982-01-15

    Both labor and management in the construction industry are concerned with the enforcement of four OSHA construction standards (regarding the use of safety belts, nets, and training) at the point of erection. This concern prompted this project which is a pilot program to evaluate the effectiveness of these standards at the point of erection in steel and precast/prestressed erection. To accomplish this objective, nine erection sites of various kinds were visited; contacts were made with unions, contractors, associations, and various OSHA officials; and data was obtained regarding fall accidents occurring at the point of erection.

  18. Importance of the C1 anterior tubercle depth and lateral mass geometry when placing C1 lateral mass screws.

    PubMed

    Wait, Scott D; Ponce, Francisco A; Colle, Kyle O; Parry, Phillip V; Sonntag, Volker K H

    2009-11-01

    We measured the variability in the size of the anterior tubercle of C1 and the optimal depth and angle of placement of C1 lateral mass screws using axial and sagittal reconstructed computed tomographic scans to determine the utility of these parameters for preoperative planning and intraoperative guidance. One hundred consecutive cervical spine computed tomographic scans were reviewed (mean patient age, 44.6 years; age range, 7-96 years). The size of the anterior tubercle of C1, bilateral depths of optimal screw placement in the axial and sagittal planes, and optimal angles of placement in the axial and sagittal planes were measured in a standardized manner using the measuring tool included in our radiology server software. These measurements were correlated with age and sex. The mean depth of the C1 tubercle was 6.9 mm (range, 2.7-11.2 mm; standard deviation, 1.7 mm). The depth of the C1 tubercle tended to increase with age, but the relationship was not significant. The optimal screw depth in the sagittal plane was significantly greater than in the axial plane (right 2.09 versus 1.93 cm; left 2.07 versus 1.91 cm). The depth of the right lateral mass increased significantly with age. No other relationships reached significance. The depth of the anterior tubercle of C1 varies considerably and should be studied carefully before using lateral fluoroscopy of this structure to guide depth of C1 lateral mass screw placement. Optimal angles and depths of placement of C1 lateral mass screws vary widely and should be examined preoperatively to plan appropriate depth and trajectory.

  19. Using Scratch with Primary School Children: An Evaluation of Games Constructed to Gauge Understanding of Programming Concepts

    ERIC Educational Resources Information Center

    Wilson, Amanda; Hainey, Thomas; Connolly, Thomas M.

    2013-01-01

    Newer approaches such as games-based learning (GBL) and games-based construction are being adopted to motivate and engage students within the Curriculum for Excellence (CfE) in Scotland. GBL and games-based construction suffer from a dearth of empirical evidence supporting their validity as teaching and learning approaches. To address this issue…

  20. Using Scratch with Primary School Children: An Evaluation of Games Constructed to Gauge Understanding of Programming Concepts

    ERIC Educational Resources Information Center

    Wilson, Amanda; Hainey, Thomas; Connolly, Thomas M.

    2013-01-01

    Newer approaches such as games-based learning (GBL) and games-based construction are being adopted to motivate and engage students within the Curriculum for Excellence (CfE) in Scotland. GBL and games-based construction suffer from a dearth of empirical evidence supporting their validity as teaching and learning approaches. To address this issue…

  1. Project W-320, 241-C-106 sluicing: Construction specification W-320-C1

    SciTech Connect

    Bailey, J.W.

    1998-07-20

    Project W-320, Waste Retrieval Sluicing System (WRSS), specification is for procurement, fabrication and installation of equipment at the C Tank Farm, including Operator Station and some equipment just outside the C Tank Farm fence, necessary to support the sluicing operation. Work consists of furnishing labor, equipment, and materials to provide the means to procure materials and equipment, fabricate items, excavate and place concrete, and install equipment, piping, wiring, and structures in accordance with the Contract Documents. Major work elements include: Excavation for process and fire protection piping, electrical conduit trenches, and foundations for small structures; Placement of concrete cover blocks, foundations, and equipment pads; Procurement and installation of double walled piping, electrical conduit, fire and raw water piping, chilled water piping, and electrical cable; Procurement and installation of above-ground ventilation system piping between the (HVAC) Process building and Tank C-106; Core drill existing concrete; Furnish and installation of electrical distribution equipment; Installation of the concrete foundation, and assembly installation of the two Seismic Shutdown Systems with Environmental Enclosures; Fabrication and installation of in-pit pipe jumpers, including related valves, instruments and wiring; and Installation of a vertical submersible pump, horizontal booster pump, and winch assembly into tank access riser pits.

  2. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Corporation was owned in equal proportions by A and his partner, AP. Except in the case of distributions in... property made on June 15, 1957, between A and the N Corporation or AP and the N Corporation since each... X, and A's partner, AP, owned 60 percent in value of the outstanding stock of X. The...

  3. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Corporation was owned in equal proportions by A and his partner, AP. Except in the case of distributions in... property made on June 15, 1957, between A and the N Corporation or AP and the N Corporation since each... X, and A's partner, AP, owned 60 percent in value of the outstanding stock of X. The...

  4. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Corporation was owned in equal proportions by A and his partner, AP. Except in the case of distributions in... property made on June 15, 1957, between A and the N Corporation or AP and the N Corporation since each... X, and A's partner, AP, owned 60 percent in value of the outstanding stock of X. The...

  5. 26 CFR 1.267(c)-1 - Constructive ownership of stock.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Corporation was owned in equal proportions by A and his partner, AP. Except in the case of distributions in... property made on June 15, 1957, between A and the N Corporation or AP and the N Corporation since each... X, and A's partner, AP, owned 60 percent in value of the outstanding stock of X. The...

  6. What Matters for Excellence in PhD Programs? Latent Constructs of Doctoral Program Quality Used by Early Career Social Scientists

    ERIC Educational Resources Information Center

    Morrison, Emory; Rudd, Elizabeth; Zumeta, William; Nerad, Maresi

    2011-01-01

    This paper unpacks how social science doctorate-holders come to evaluate overall excellence in their PhD training programs based on their domain-specific assessments of aspects of their programs. Latent class analysis reveals that social scientists 6-10 years beyond their PhD evaluate the quality of their doctoral program with one of two…

  7. Logan Library, Final Performance Report for Library Services and Construction Act (LSCA) Title VI, Library Literacy Program.

    ERIC Educational Resources Information Center

    Steinhoff, Nadene; Jenkins, Ronald

    The Bridgerland Literacy program of Logan Library (Logan, Utah) involved recruitment, retention, public awareness, training, basic literacy, collection development, tutoring, computer assisted, employment oriented, intergenerational/family, and English as a Second Language (ESL) programs. The program served a community of 50,000-100,000 people,…

  8. Department of the Navy FY-94 Budget Estimates. Naval and Marine Corps Reserve. Military Construction Program. Justification Data Submitted to Congress April 1993

    DTIC Science & Technology

    1993-04-01

    PROGRAM CONSIDERATIONS (3) PROGRAM AND FINANCING SUMMARY (4) OBJECT CLASSIFICATION SUMMARY FY 1994 PROJECT DD 1390’s AND DD 1391’s...and Maintenance, Marine Corps Reserve - Maintenance and Repair 730 - Minor Construction 1,470 Resolution Trust Corporation Following guidance provided...the Resolution Trust Corporation or any similar entity. 8 *~C aa -- Mr CID 0 Nm 40 - a ~ ~ ~ ~ ~ W Nq 4D a~a ~ q9 a a w I a a0 1 in a a aa * a4 .. N00

  9. Total synthesis of (-)-CP2-disorazole C1.

    PubMed

    Hopkins, Chad D; Schmitz, John C; Chu, Edward; Wipf, Peter

    2011-08-05

    The total synthesis of a bis-cyclopropane analog of the antimitotic natural product (-)-disorazole C(1) was accomplished in 23 steps and 1.1% overall yield. A vinyl cyclopropane cross-metathesis reaction generated a key (E)-alkene segment of the target molecule. IC(50) determinations of (-)-CP(2)-disorazole C(1) in human colon cancer cell lines indicated low nanomolar cytotoxic properties. Accordingly, this synthetic bioisostere represents the first biologically active disorazole analog not containing a conjugated diene or polyene substructure element.

  10. Workshops and incentive loans program for construction of solar greenhouses, grain dryers, window boxes and food dryers. Final performance report

    SciTech Connect

    Walker, D.H.

    1982-02-01

    A Solar Loan Fund was established to provide low-interest incentive loans to families desiring to construct their own solar devices, the only stipulations being allowance of reasonable public visitation and monitoring and employment of parish-trained construction teams if labor is to be hired. About 30 vocational agriculture students built window box collector units as part of their classroom experience, trying several designs. Later, 12 to 15 families built window box collectors for their use. A week long Energy Responsibility: Today and Tomorrow workshop was held involving construction projects and mini-seminars. Another workshop was held to construct bread box type solar hot water heaters, and yet another to build solar food dryers. (LEW)

  11. 25 CFR 1000.243 - What special provisions must be included in an AFA that contains a construction program?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.243 What special provisions... implementation of the AFA, including but not limited to: (1) The use of architects and engineers licensed to...

  12. 25 CFR 1000.243 - What special provisions must be included in an AFA that contains a construction program?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.243 What special provisions... implementation of the AFA, including but not limited to: (1) The use of architects and engineers licensed to...

  13. 25 CFR 1000.243 - What special provisions must be included in an AFA that contains a construction program?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.243 What special provisions... implementation of the AFA, including but not limited to: (1) The use of architects and engineers licensed to...

  14. 25 CFR 1000.243 - What special provisions must be included in an AFA that contains a construction program?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.243 What special provisions... implementation of the AFA, including but not limited to: (1) The use of architects and engineers licensed to...

  15. 25 CFR 1000.243 - What special provisions must be included in an AFA that contains a construction program?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Construction § 1000.243 What special provisions... implementation of the AFA, including but not limited to: (1) The use of architects and engineers licensed to...

  16. Elucidating the Mechanism of Gain of Toxic Function From Mutant C1 Inhibitor Proteins in Hereditary Angioedema

    DTIC Science & Technology

    2015-10-01

    in Hereditary Angioedema PRINCIPAL INVESTIGATOR: Dr. Bruce Zuraw, M.D. CONTRACTING: ORGANIZATION Veterans Medical Research Foundation San...C1 Inhibitor 5a. CONTRACT NUMBER Proteins in Hereditary Angioedema 5b. GRANT NUMBER W81XWH-14-1-0506 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Dr...hypothesis that unique structural characteristics of C1INH make it more susceptible to GOTF than other serpins. 15. SUBJECT TERMS Hereditary

  17. 26 CFR 1.662(c)-1 - Different taxable years.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Different taxable years. 1.662(c)-1 Section 1...)-1 Different taxable years. If a beneficiary has a different taxable year (as defined in section 441 or 442) from the taxable year of an estate or trust, the amount he is required to include in gross...

  18. 26 CFR 1.1092(c)-1 - Qualified covered calls.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 11 2013-04-01 2013-04-01 false Qualified covered calls. 1.1092(c)-1 Section 1... stock price of $14.84. Using the bench marks for an equity option with standardized terms with an adjusted applicable stock price of $14.84, the highest available strike price less than the...

  19. 26 CFR 1.1092(c)-1 - Qualified covered calls.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 11 2014-04-01 2014-04-01 false Qualified covered calls. 1.1092(c)-1 Section 1... stock price of $14.84. Using the bench marks for an equity option with standardized terms with an adjusted applicable stock price of $14.84, the highest available strike price less than the...

  20. 26 CFR 31.3401(c)-1 - Employee.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Income Tax at Source § 31.3401(c)-1 Employee. (a) The term employee includes every individual performing... relationship of employer and employee. The term includes officers and employees, whether elected or appointed... examination of the particular facts of each case. (e) If the relationship of employer and employee exists, the...