High-Dose Continuous Infusion Beta-lactam Antibiotics for the Treatment of Resistant Pseudomonas aeruginosa Infections in Immunocompromised Patients

PubMed Central

Moriyama, Brad; Henning, Stacey A.; Childs, Richard; Holland, Steven M.; Anderson, Victoria L.; Morris, John C.; Wilson, Wyndham H.; Drusano, George L.; Walsh, Thomas J.

2011-01-01

OBJECTIVE To report a case series of high-dose continuous infusion beta-lactam antibiotics for the treatment of resistant Pseudomonas aeruginosa infections. CASE SUMMARY Continuous infusion ceftazidime or aztreonam was administered to achieve target drug levels at or above the MIC when possible in three patients with P. aeruginosa infections. The maximal calculated target drug level was 100 mg/L. In the first patient with primary immunodeficiency, neutropenia, and aggressive cutaneous T cell lymphoma/leukemia, continuous infusion ceftazidime (6.5 to 9.6 g/day) was used to successfully treat multidrug-resistant P. aeruginosa bacteremia. In the second patient with leukocyte adhesion deficiency type 1, continuous infusion aztreonam (8.4 g/day) was used to successfully treat multidrug-resistant P. aeruginosa wound infections. In the third patient with severe aplastic anemia, continuous infusion ceftazidime (7 to 16.8 g/day) was used to treat P. aeruginosa pneumonia and bacteremia. In each patient, the bacteremia cleared, infected wounds healed, and pneumonia improved in response to continuous infusion ceftazidime or aztreonam. DISCUSSION Treatment strategies for multidrug-resistant P. aeruginosa infections are limited. A novel treatment strategy when no other options are available is the administration of existing beta-lactam antibiotics by continuous infusion in order to maximize their pharmacodynamic activity. High-dose continuous infusion ceftazidime or aztreonam was used for the successful treatment of resistant systemic P. aeruginosa infections in three chronically immunocompromised patients. CONCLUSION Continuous infusion beta-lactam antibiotics are a potentially useful treatment strategy for resistant P. aeruginosa infections in immunocompromised patients. PMID:20371747

78 FR 56775 - Waste Confidence-Continued Storage of Spent Nuclear Fuel

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-13

... radiological impacts of spent nuclear fuel and high-level waste disposal. DATES: Submit comments on the... determination. The ``Offsite radiological impacts of spent nuclear fuel and high-level waste disposal'' issue.... Geologic Repository--Technical Feasibility and Availability C3. Storage of Spent Nuclear Fuel C3.a...

From the past to the globalized future for Caribbean birds

Treesearch

Joseph Wunderle Jr.

2008-01-01

Extinctions of Caribbean animals were well underway during the period of Amerindian occupation and have continued since the arrival of Columbus. Despite high extinction rates, the Caribbean still retains high levels of terrestrial biodiversity and, for some taxa, exceptionally high levels of endemism relative to other parts of the world. The fate of the Caribbean’s...

Sleep Disrupts High-Level Speech Parsing Despite Significant Basic Auditory Processing.

PubMed

Makov, Shiri; Sharon, Omer; Ding, Nai; Ben-Shachar, Michal; Nir, Yuval; Zion Golumbic, Elana

2017-08-09

The extent to which the sleeping brain processes sensory information remains unclear. This is particularly true for continuous and complex stimuli such as speech, in which information is organized into hierarchically embedded structures. Recently, novel metrics for assessing the neural representation of continuous speech have been developed using noninvasive brain recordings that have thus far only been tested during wakefulness. Here we investigated, for the first time, the sleeping brain's capacity to process continuous speech at different hierarchical levels using a newly developed Concurrent Hierarchical Tracking (CHT) approach that allows monitoring the neural representation and processing-depth of continuous speech online. Speech sequences were compiled with syllables, words, phrases, and sentences occurring at fixed time intervals such that different linguistic levels correspond to distinct frequencies. This enabled us to distinguish their neural signatures in brain activity. We compared the neural tracking of intelligible versus unintelligible (scrambled and foreign) speech across states of wakefulness and sleep using high-density EEG in humans. We found that neural tracking of stimulus acoustics was comparable across wakefulness and sleep and similar across all conditions regardless of speech intelligibility. In contrast, neural tracking of higher-order linguistic constructs (words, phrases, and sentences) was only observed for intelligible speech during wakefulness and could not be detected at all during nonrapid eye movement or rapid eye movement sleep. These results suggest that, whereas low-level auditory processing is relatively preserved during sleep, higher-level hierarchical linguistic parsing is severely disrupted, thereby revealing the capacity and limits of language processing during sleep. SIGNIFICANCE STATEMENT Despite the persistence of some sensory processing during sleep, it is unclear whether high-level cognitive processes such as speech parsing are also preserved. We used a novel approach for studying the depth of speech processing across wakefulness and sleep while tracking neuronal activity with EEG. We found that responses to the auditory sound stream remained intact; however, the sleeping brain did not show signs of hierarchical parsing of the continuous stream of syllables into words, phrases, and sentences. The results suggest that sleep imposes a functional barrier between basic sensory processing and high-level cognitive processing. This paradigm also holds promise for studying residual cognitive abilities in a wide array of unresponsive states. Copyright © 2017 the authors 0270-6474/17/377772-10$15.00/0.

Influence of the washing program on the blood processing performance of a continuous autotransfusion device.

PubMed

Yoon, Chiyul; Noh, Seungwoo; Lee, Jung Chan; Ko, Sung Ho; Ahn, Wonsik; Kim, Hee Chan

2014-03-01

The continuous autotransfusion system has been widely used in surgical operations. It is known that if oil is added to blood, and this mixture is then processed by an autotransfusion device, the added oil is removed and reinfusion of fat is prevented by the device. However, there is no detailed report on the influence of the particular washing program selected on the levels of blood components including blood fat after continuous autotransfusion using such a system. Fresh bovine blood samples were processed by a commercial continuous autotransfusion device using the "emergency," "quality," and "high-quality" programs, applied in random order. Complete blood count (CBC) and serum chemistry were analyzed to determine how the blood processing performance of the device changes with the washing program applied. There was no significant difference in the CBC results obtained with the three washing programs. Although all of the blood lipids in the processed blood were decreased compared to those in the blood before processing, the levels of triglyceride, phospholipid, and total cholesterol after processing via the emergency program were significantly higher than those present after processing via the quality and high-quality programs. Although the continuous autotransfusion device provided consistent hematocrit quality, the levels of some blood lipid components showed significant differences among the washing programs.

Tips for Living with Scleroderma

MedlinePlus

... raw foods – about 50% of your diet – especially dark, leafy greens to provide chlorophyll and other nutrients. ... normal levels to dangerously high levels in a matter of days. If it continues without treatment, the ...

[Equivalent continuous noise level in neonatal intensive care unit associated to burnout syndrome].

PubMed

Garrido Galindo, A P; Camargo Caicedo, Y; Vélez-Pereira, A M

2015-01-01

Noise levels in neonatal intensive care units allow the appearance of symptoms associated with burnout such as stress, irritability, fatigue and emotional instability on health care personnel. The aim of this study was to evaluate the equivalent continuous noise levels in the neonatal intensive care unit and compare the results with noise levels associated with the occurrence of burnout syndrome on the care team. Continuous sampling was conducted for 20 days using a type I sound level meter on the unit. The maximum, the ninetieth percentile and the equivalent continuous noise level (Leq) values were recorded. Noise level is reported in the range of 51.4-77.6 decibels A (dBA) with an average of 64 dBA, 100.6 dBA maximum, and average background noise from 57.9 dBA. Noise levels exceed the standards suggested for neonatal intensive care units, are close to maximum values referred for noise exposure in the occupational standards and to noise levels associated with the onset of burnout; thus allowing to infer the probability of occurrence of high levels of noise present in the unit on the development of burnout in caregivers. Copyright © 2013 Elsevier España, S.L.U. y SEEIUC. All rights reserved.

Roster of Astronomy Departments with Enrollment and Degree Data, 2014: Results from the 2014 Survey of Enrollments and Degrees. Focus On

ERIC Educational Resources Information Center

Nicholson, Starr; Mulvey, Patrick J.

2015-01-01

Undergraduate astronomy enrollments in the US continue to rise with junior and senior level enrollments exceeding the previous year's all-time high. The increasing undergraduate enrollments have produced 428 bachelor's in the 2013-14 academic year, also an all-time high. Undergraduate astronomy degree production will continue to rise given the…

Roster of Physics Departments with Enrollment and Degree Data, 2015: Results from the 2015 Survey of Enrollments and Degrees. Focus On

ERIC Educational Resources Information Center

Nicholson, Starr; Mulvey, Patrick J.

2016-01-01

Physics bachelor's degree production continues to increase, with the 8,122 bachelor's awarded representing yet another all-time high. Further increases in physics bachelor's degree production are anticipated as undergraduate junior- and senior-level enrollments continue to climb. The all-time high of 1,860 physics PhDs conferred in the class of…

Roster of Astronomy Departments with Enrollment and Degree Data, 2015: Results from the 2015 Survey of Enrollments and Degrees. Focus On

ERIC Educational Resources Information Center

Nicholson, Starr; Mulvey, Patrick J.

2016-01-01

Physics bachelor's degree production continues to increase, with the 8,122 bachelor's awarded representing yet another all-time high. Further increases in physics bachelor's degree production are anticipated as undergraduate junior- and senior-level enrollments continue to climb. The all-time high of 1,860 physics PhDs conferred in the class of…

Continuing Education as a National Capital Investment.

ERIC Educational Resources Information Center

Striner, Herbert E.

The constant readjustment that is necessary in a socially and economically complex society is discussed. The point is made that in recent years the United States has been confronted by an increasingly urgent series of economic problems. Intractably high levels of unemployment have accompanied abnormally high levels of inflation. It is also pointed…

High School Mathematics: State-Level Curriculum Standards and Graduation Requirements

ERIC Educational Resources Information Center

Reys, Barbara J.; Dingman, Shannon; Nevels, Nevels; Teuscher, Dawn

2007-01-01

In a continuing effort to improve student-learning opportunities in mathematics, state departments of education have focused on articulating standards or learning goals at all levels, including high school mathematics. A review of K-8 mathematics curriculum standards (many of which have been published since 2002) compiled by staff from the Center…

Variability, Constraints, and Creativity: Shedding Light on Claude Monet.

ERIC Educational Resources Information Center

Stokes, Patricia D.

2001-01-01

Discusses how creative individuals maintain high levels of variability, examining how Claude Monet's habitually high level of variability in painting was acquired during his childhood and early apprenticeship and maintained throughout his adult career by a continuous series of task constraints imposed by the artist on his own work. For Monet,…

Multiple Theory Formation in High-Level Perception. Technical Report No. 38.

ERIC Educational Resources Information Center

Woods, William A.

This paper is concerned with the process of human reading as a high-level perceptual task. Drawing on insights from artificial-intelligence research--specifically, research in natural language processing and continuous speech understanding--the paper attempts to present a fairly concrete picture of the kinds of hypothesis formation and inference…

The Relationship between Professional Learning Community Implementation and Academic Achievement and Graduation Rates in Georgia High Schools

ERIC Educational Resources Information Center

Hardinger, Regina Gail

2013-01-01

Many educational administrators in Georgia continue to struggle with low student academic achievement and low high school graduation rates. DuFour's professional learning community (PLC) theory suggests a positive relationship between levels of PLC implementation and academic achievement and between levels of PLC implementation and graduation…

10 CFR 60.140 - General requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... and it will continue until permanent closure. (c) The program shall include in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to accomplish the objective as... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

10 CFR 60.140 - General requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... and it will continue until permanent closure. (c) The program shall include in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to accomplish the objective as... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

10 CFR 60.140 - General requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... and it will continue until permanent closure. (c) The program shall include in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to accomplish the objective as... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

10 CFR 60.140 - General requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... and it will continue until permanent closure. (c) The program shall include in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to accomplish the objective as... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

10 CFR 60.140 - General requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... and it will continue until permanent closure. (c) The program shall include in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to accomplish the objective as... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

Extracorporeal treatment with high-volume continuous venovenous hemodiafiltration and charcoal-based sorbent hemoperfusion for severe metformin-associated lactic acidosis

PubMed Central

Garg, Suneel Kumar; Singh, Omender; Deepak, Desh; Singh, Akhilesh; Yadav, Rohit; Vashist, Kirti

2016-01-01

We present a case of a 49-year-old female with an alleged history of ingestion of approximately 100 tablets of metformin (850 mg each). Investigations revealed severe lactic acidosis with lactate levels of 13.5 mmol/L and pH of 7.17. This indicates severe toxicity and is associated with a high mortality. Charcoal-based sorbent hemoperfusion was done as a desperate effort, as patient continued to deteriorate despite supportive care and high-volume continuous venovenous hemodiafiltration. The patient survived despite metformin-associated lactic acidosis related to severe metformin toxicity. PMID:27275079

40 CFR 60.4880 - How do I develop a site-specific monitoring plan for my continuous monitoring, bag leak detection...

Code of Federal Regulations, 2012 CFR

2012-07-01

... section are met. (A) The zero (low-level), mid-level (if applicable), or high-level calibration drift... representative of the relative or absolute particulate matter loadings for each exhaust stack, roof vent, or...

40 CFR 60.4880 - How do I develop a site-specific monitoring plan for my continuous monitoring, bag leak detection...

Code of Federal Regulations, 2014 CFR

2014-07-01

... section are met. (A) The zero (low-level), mid-level (if applicable), or high-level calibration drift... representative of the relative or absolute particulate matter loadings for each exhaust stack, roof vent, or...

40 CFR 60.4880 - How do I develop a site-specific monitoring plan for my continuous monitoring, bag leak detection...

Code of Federal Regulations, 2013 CFR

2013-07-01

... section are met. (A) The zero (low-level), mid-level (if applicable), or high-level calibration drift... representative of the relative or absolute particulate matter loadings for each exhaust stack, roof vent, or...

Separation and purification of enzymes by continuous pH-parametric pumping

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, S.Y.; Lin, C.K.; Juang, L.Y.

1985-10-01

Trypsin and chymotrypsin were separated from porcine pancreas extract by continuous pH-parametric pumping. CHOM (chicken ovomucoid) was convalently bound to laboratory-prepared crab chitin with glutaraldehyde to form an affinity adsorbent of trypsin. The pH levels of top and bottom feeds were 8.0 and 2.5, respectively. Similar inhibitor, DKOM (duck ovomucoid), and pH levels 8.0 and 2.0 for top and bottom feeds, respectively, were used for separation and purification of chymotrypsin. e-Amino caproyl-D-tryptophan methyl ester was coupled to chitosan to form an affinity adsorbent for stem bromelain. The pH levels were 8.7 and 3.0. Separation continued fairly well with high yield,more » e.g., 95% recovery of trypsin after continuous pumping of 10 cycles. Optimum operational conditions for concentration and purification of these enzymes were investigated. The results showed that the continuous pH-parametric pumping coupled with affinity chromatography is effective for concentration and purification of enzymes. 19 references.« less

Phase plate technology for laser marking of magnetic discs

DOEpatents

Neuman, Bill; Honig, John; Hackel, Lloyd; Dane, C. Brent; Dixit, Shamasundar

1998-01-01

An advanced design for a phase plate enables the distribution of spots in arbitrarily shaped patterns with very high uniformity and with a continuously or near-continuously varying phase pattern. A continuous phase pattern eliminates large phase jumps typically expected in a grating that provides arbitrary shapes. Large phase jumps increase scattered light outside of the desired pattern, reduce efficiency and can make the grating difficult to manufacture. When manufacturing capabilities preclude producing a fully continuous grating, the present design can be easily adapted to minimize manufacturing errors and maintain high efficiencies. This continuous grating is significantly more efficient than previously described Dammann gratings, offers much more flexibility in generating spot patterns and is easier to manufacture and replicate than a multi-level phase grating.

High phosphate diet increases arterial blood pressure via a parathyroid hormone mediated increase of renin.

PubMed

Bozic, Milica; Panizo, Sara; Sevilla, Maria A; Riera, Marta; Soler, Maria J; Pascual, Julio; Lopez, Ignacio; Freixenet, Montserrat; Fernandez, Elvira; Valdivielso, Jose M

2014-09-01

There is growing evidence suggesting that phosphate intake is associated with blood pressure levels. However, data from epidemiological studies show inconsistent results. The present study was designed to evaluate the effect of high circulating phosphorus on arterial blood pressure of healthy rats and to elucidate the potential mechanism that stands behind this effect. Animals fed a high phosphate diet for 4 weeks showed an increase in blood pressure, which returned to normal values after the addition of a phosphate binder (lanthanum carbonate) to the diet. The expression of renin in the kidney was higher, alongside an increase in plasma renin activity, angiotensin II (Ang II) levels and left ventricular hypertrophy. The addition of the phosphate binder blunted the increase in renin and Ang II levels. The levels of parathyroid hormone (PTH) were also higher in animals fed a high phosphate diet, and decreased when the phosphate binder was present in the diet. However, blood P levels remained elevated. A second group of rats underwent parathyroidectomy and received a continuous infusion of physiological levels of PTH through an implanted mini-osmotic pump. Animals fed a high phosphate diet with continuous infusion of PTH did not show an increase in blood pressure, although blood P levels were elevated. Finally, unlike with verapamil, the addition of losartan to the drinking water reverted the increase in blood pressure in rats fed a high phosphate diet. The results of this study suggest that a high phosphate diet increases arterial blood pressure through an increase in renin mediated by PTH.

[Comprehensive sexual education in Mexico: an analysis of coverage, comprehensiveness and continuity of contents in Mexican public and private schools].

PubMed

Rojas, Rosalba; Castro, Filipa de; Villalobos, Aremis; Allen-Leigh, Betania; Romero, Martin; Braverman-Bronstein, Ariela; Uribe, Patricia

2017-01-01

To analyze coverage of comprehensive sex education (CSE) in high schools in Mexico and describe whether it is comprehensive, homogeneous and has continuity based on student reports of exposure to topics in three dimensions: reproductive and sexual health, self-efficacy and rights and relations. Within a probabilistic, cross-sectional survey with stratified, cluster sampling, a nationally representative sample of 3 824 adolescents attending 45 public and private high-schools in urban and rural areas completed questionnaires on CSE. The proportion of adolescents reporting having received sex education from school personnel varies depending on topics and grade level. Topics most frequently covered are those related to sexual and reproductive health while rights and relations are least frequently dealt with. Most sex education topics are covered during junior high school and much less frequently in elementary or high school. CSE needs to be comprehensive and homogenous in terms of content, ensure inclusion of priority topics, meet national and international recommendations, ensure continuity and adapt contents to student age through all education levels.

Method for generating high-energy and high repetition rate laser pulses from CW amplifiers

DOEpatents

Zhang, Shukui

2013-06-18

A method for obtaining high-energy, high repetition rate laser pulses simultaneously using continuous wave (CW) amplifiers is described. The method provides for generating micro-joule level energy in pico-second laser pulses at Mega-hertz repetition rates.

Continuous real-time in vivo measurement of cerebral nitric oxide supports theoretical predictions of an irreversible switching in cerebral ROS after sufficient exposure to external toxins.

PubMed

Finnerty, Niall J; O'Riordan, Saidhbhe L; Lowry, John P; Cloutier, Mathieu; Wellstead, Peter

2013-01-01

Mathematical models of the interactions between alphasynuclein (αS) and reactive oxygen species (ROS) predict a systematic and irreversible switching to damagingly high levels of ROS after sufficient exposure to risk factors associated with Parkinson's disease (PD). We tested this prediction by continuously monitoring real-time changes in neurochemical levels over periods of several days in animals exposed to a toxin known to cause Parkinsonian symptoms. Nitric oxide (NO) sensors were implanted in the brains of freely moving rats and the NO levels continuously recorded while the animals were exposed to paraquat (PQ) injections of various amounts and frequencies. Long-term, real-time measurement of NO in a cohort of animals showed systematic switching in levels when PQ injections of sufficient size and frequency were administered. The experimental observations of changes in NO imply a corresponding switching in endogenous ROS levels and support theoretical predictions of an irreversible change to damagingly high levels of endogenous ROS when PD risks are sufficiently large. Our current results only consider one form of PD risk, however, we are sufficiently confident in them to conclude that: (i) continuous long-term measurement of neurochemical dynamics provide a novel way to measure the temporal change and system dynamics which determine Parkinsonian damage, and (ii) the bistable feedback switching predicted by mathematical modelling seems to exist and that a deeper analysis of its characteristics would provide a way of understanding the pathogenic mechanisms that initiate Parkinsonian cell damage.

Prognosis and Continuity of Child Mental Health Problems from Preschool to Primary School: Results of a Four-Year Longitudinal Study

ERIC Educational Resources Information Center

Beyer, Thomas; Postert, Christian; Muller, Jorg M.; Furniss, Tilman

2012-01-01

In a four-year longitudinal study, changes in and continuity of behavioral and emotional problems were examined in 814 subjects from kindergarten to primary school. Mental health problems were assessed by means of the Child Behavior Checklist (CBCL). The distribution of the CBCL broadband groups revealed a high level of continuity of internalizing…

Spectrum-agile hundred-watt-level high-power random fiber laser enabled by watt-level tunable optical filter

NASA Astrophysics Data System (ADS)

Ye, Jun; Xu, Jiangming; Song, Jiaxin; Wu, Hanshuo; Zhang, Hanwei; Wu, Jian; Zhou, Pu

2018-06-01

Through high-fidelity numerical modeling and careful system-parameter design, we demonstrate the spectral manipulation of a hundred-watt-level high-power random fiber laser (RFL) by employing a watt-level tunable optical filter. Consequently, a >100-W RFL with the spectrum-agile property is achieved. The central wavelength can be continuously tuned with a range of ∼20 nm, and the tuning range of the full width at half maximum linewidth, which is closely related to the central wavelength, covers ∼1.1 to ∼2.7 times of the minimum linewidth.

Radiometric temperature reference

NASA Technical Reports Server (NTRS)

Monford, L. G., Jr.

1969-01-01

Radiometric Temperature Reference uses a thermistor as both a heating and sensing element to maintain its resistance at a preselected level to continuously control the power supplying it. The fixed infrared radiation level must be simple, rugged, and capable of high temperature operation.

Professional Development in the Field of Education

ERIC Educational Resources Information Center

Moore, Jeanne L. Hager

2009-01-01

The process of continual growth and development in the teaching profession represents a common value among education professionals. Federal and state laws maintain that teachers must continue to study. These mandates, pronounced at federal, state, and local levels to create high academic standards for students, must be met through quality…

High level continuity for coordinate generation with precise controls

NASA Technical Reports Server (NTRS)

Eiseman, P. R.

1982-01-01

Coordinate generation techniques with precise local controls have been derived and analyzed for continuity requirements up to both the first and second derivatives, and have been projected to higher level continuity requirements from the established pattern. The desired local control precision was obtained when a family of coordinate surfaces could be uniformly distributed without a consequent creation of flat spots on the coordinate curves transverse to the family. Relative to the uniform distribution, the family could be redistributed from an a priori distribution function or from a solution adaptive approach, both without distortion from the underlying transformation which may be independently chosen to fit a nontrivial geometry and topology.

A School and Work Program in An Adult Manpower Setting for Potential Dropouts Needing Educational Redirection. Evaluation of State Urban Education Programs in New York City 1968-69.

ERIC Educational Resources Information Center

Flicker, Bernard

The objectives of this High School Redirection Project were to redirect potential dropouts to continue full-time education and training with an educational-vocational plan, to provide high school dropouts with job skills that will enable them to enter the labor market on the highest possible level while continuing to upgrade their skills on a…

Phase plate technology for laser marking of magnetic discs

DOEpatents

Neuman, B.; Honig, J.; Hackel, L.; Dane, C.B.; Dixit, S.

1998-10-27

An advanced design for a phase plate enables the distribution of spots in arbitrarily shaped patterns with very high uniformity and with a continuously or near-continuously varying phase pattern. A continuous phase pattern eliminates large phase jumps typically expected in a grating that provides arbitrary shapes. Large phase jumps increase scattered light outside of the desired pattern, reduce efficiency and can make the grating difficult to manufacture. When manufacturing capabilities preclude producing a fully continuous grating, the present design can be easily adapted to minimize manufacturing errors and maintain high efficiencies. This continuous grating is significantly more efficient than previously described Dammann gratings, offers much more flexibility in generating spot patterns and is easier to manufacture and replicate than a multi-level phase grating. 3 figs.

Factors Affecting Noise Levels of High-Speed Handpieces

DTIC Science & Technology

2012-06-01

regarding handpiece -induced hearing loss among dental providers remains equivocal, warranting continued concern. Moreover, handpiece noise may hinder...turbines can be applied to dental handpieces to reduce noise emission without compromising performance. Methods: Three samples of three brands of...high-speed dental handpieces were chosen. Following baseline measurements for speed (rpm) and noise level (dB), the following internal modifications

The Foci of In-Action Professional Judgement and Decision-Making in High-Level Adventure Sports Coaching Practice

ERIC Educational Resources Information Center

Collins, Loel; Collins, Dave

2017-01-01

This article continues a theme of previous investigations by the authors and examines the focus of in-action reflection as a component of professional judgement and decision-making (PJDM) processes in high-level adventure sports coaching. We utilised a thematic analysis approach to investigate the decision-making practices of a sample of…

High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats.

PubMed

Allain, Florence; Bouayad-Gervais, Karim; Samaha, Anne-Noël

2018-01-01

Taking high and increasing amounts of cocaine is thought to be necessary for the development of addiction. Consequently, a widely used animal model of drug self-administration involves giving animals continuous drug access during long sessions (LgA), as this produces high and escalating levels of intake. However, human cocaine addicts likely use the drug with an intermittent rather than continuous pattern, producing spiking brain cocaine levels. Using an intermittent-access (IntA) cocaine self-administration procedure in rats, we studied the relationship between escalation of cocaine intake and later incentive motivation for the drug, as measured by responding under a progressive ratio schedule of cocaine reinforcement. First, under IntA, rats escalated their cocaine use both within and between sessions. However, escalation did not predict later incentive motivation for the drug. Second, incentive motivation for cocaine was similar in IntA-rats limited to low- and non-escalating levels of drug intake (IntA-Lim) and in IntA-rats that took high and escalating levels of drug. Finally, IntA-Lim rats took much less cocaine than rats given continuous drug access during each self-administration session (LgA-rats). However, IntA-Lim rats later responded more for cocaine under a progressive ratio schedule of reinforcement. Taking large and escalating quantities of cocaine does not appear necessary to increase incentive motivation for the drug. Taking cocaine in an intermittent pattern-even in small amounts-is more effective in producing this addiction-relevant change. Thus, beyond the amount of drug taken, the temporal kinetics of drug use predict change in drug use over time.

Magnetic isolation of Plasmodium falciparum schizonts iRBCs to generate a high parasitaemia and synchronized in vitro culture.

PubMed

Mata-Cantero, Lydia; Lafuente, Maria J; Sanz, Laura; Rodriguez, Manuel S

2014-03-21

The establishment of methods for an in vitro continuous culture of Plasmodium falciparum is essential for gaining knowledge into its biology and for the development of new treatments. Previously, several techniques have been used to synchronize, enrich and concentrate P. falciparum, although obtaining cultures with high parasitaemia continues being a challenging process. Current methods produce high parasitaemia levels of synchronized P. falciparum cultures by frequent changes of culture medium or reducing the haematocrit. However, these methods are time consuming and sometimes lead to the loss of synchrony. A procedure that combines Percoll and sorbitol treatments, the use of magnetic columns, and the optimization of the in vitro culture conditions to reach high parasitaemia levels for synchronized Plasmodium falciparum cultures is described. A new procedure has been established using P. falciparum 3D7, combining previous reported methodologies to achieve in vitro parasite cultures that reach parasitaemia up to 40% at any intra-erythrocytic stage. High parasitaemia levels are obtained only one day after magnetic column purification without compromising the parasite viability and synchrony. The described procedure allows obtaining a large scale synchronized parasite culture at a high parasitaemia with less manipulations than other methods previously described.

An Examination of Business Students' Student Loan Debt and Total Debt

ERIC Educational Resources Information Center

Kuzma, Ann T.; Kuzma, John R.; Thiewes, Harold F.

2010-01-01

Under the current economic environment and its high levels of unemployment, many people are turning to university education to attain higher education or simply to upgrade their skills and avoid continued unemployment. This paper examines student workloads, debt levels, and the debt perceptions of junior- and senior-level College of Business…

Phosphate Solubilization and Gene Expression of Phosphate-Solubilizing Bacterium Burkholderia multivorans WS-FJ9 under Different Levels of Soluble Phosphate.

PubMed

Zeng, Qingwei; Wu, Xiaoqin; Wang, Jiangchuan; Ding, Xiaolei

2017-04-28

Phosphate-solubilizing bacteria (PSB) have the ability to dissolve insoluble phosphate and enhance soil fertility. However, the growth and mineral phosphate solubilization of PSB could be affected by exogenous soluble phosphate and the mechanism has not been fully understood. In the present study, the growth and mineral phosphate-solubilizing characteristics of PSB strain Burkholderia multivorans WS-FJ9 were investigated at six levels of exogenous soluble phosphate (0, 0.5, 1, 5, 10, and 20 mM). The WS-FJ9 strain showed better growth at high levels of soluble phosphate. The phosphate-solubilizing activity of WS-FJ9 was reduced as the soluble phosphate concentration increased, as well as the production of pyruvic acid. Transcriptome profiling of WS-FJ9 at three levels of exogenous soluble phosphate (0, 5, and 20 mM) identified 446 differentially expressed genes, among which 44 genes were continuously up-regulated when soluble phosphate concentration was increased and 81 genes were continuously down-regulated. Some genes related to cell growth were continuously up-regulated, which would account for the better growth of WS-FJ9 at high levels of soluble phosphate. Genes involved in glucose metabolism, including glycerate kinase, 2-oxoglutarate dehydrogenase, and sugar ABC-type transporter, were continuously down-regulated, which indicates that metabolic channeling of glucose towards the phosphorylative pathway was negatively regulated by soluble phosphate. These findings represent an important first step in understanding the molecular mechanisms of soluble phosphate effects on the growth and mineral phosphate solubilization of PSB.

Danger in the Classroom: The Continuing Problem of Asbestos in the Public Schools.

ERIC Educational Resources Information Center

Lang, Robert D.

Asbestos in school buildings continues to threaten the future health of children. Because of prolonged exposure while their metabolism and activity levels are relatively high and their cellular development is relatively rapid, children and adolescents have a lifetime risk of developing asbestos-related diseases--such as asbestosis, mesothelioma,…

Continuing Education in Later Adulthood: Implications for Program Development for Elderly Guest Students.

ERIC Educational Resources Information Center

Dellmann-Jenkins, Mary M.; And Others

1985-01-01

Identified factors that would positively influence the decisions of individuals over sixty years of age to participate in cost-free continuing education programs. Females subjects (N=65) completed questionnaires, and indicated a high level of interest in taking geology, political science, world and art history, music and literature. (BH)

40 CFR 146.15 - Class I municipal disposal well alternative authorization in certain parts of Florida.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) UNDERGROUND INJECTION CONTROL PROGRAM... ground water monitoring data generated pursuant to regulatory requirements governing operation of Class I...-600.420(1)(d), and using high-level disinfection in a manner that is no less stringent than the...

40 CFR 146.15 - Class I municipal disposal well alternative authorization in certain parts of Florida.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) UNDERGROUND INJECTION CONTROL PROGRAM... ground water monitoring data generated pursuant to regulatory requirements governing operation of Class I...-600.420(1)(d), and using high-level disinfection in a manner that is no less stringent than the...

40 CFR 146.15 - Class I municipal disposal well alternative authorization in certain parts of Florida.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) UNDERGROUND INJECTION CONTROL PROGRAM... ground water monitoring data generated pursuant to regulatory requirements governing operation of Class I...-600.420(1)(d), and using high-level disinfection in a manner that is no less stringent than the...

40 CFR 146.15 - Class I municipal disposal well alternative authorization in certain parts of Florida.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) UNDERGROUND INJECTION CONTROL PROGRAM... ground water monitoring data generated pursuant to regulatory requirements governing operation of Class I...-600.420(1)(d), and using high-level disinfection in a manner that is no less stringent than the...

40 CFR 146.15 - Class I municipal disposal well alternative authorization in certain parts of Florida.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) UNDERGROUND INJECTION CONTROL PROGRAM... ground water monitoring data generated pursuant to regulatory requirements governing operation of Class I...-600.420(1)(d), and using high-level disinfection in a manner that is no less stringent than the...

Noise levels of neonatal high-flow nasal cannula devices--an in-vitro study.

PubMed

König, Kai; Stock, Ellen L; Jarvis, Melanie

2013-01-01

Excessive ambient noise levels have been identified as a potential risk factor for adverse outcome in very preterm infants. Noise level measurements for continuous positive airway pressure (CPAP) devices demonstrated that these constantly exceed current recommendations. The use of high-flow nasal cannula (HFNC) as an alternative non-invasive ventilation modality has become more popular in recent years in neonatal care. To study noise levels of two HFNC devices commonly used in newborns. As a comparison, noise levels of a continuous flow CPAP device were also studied. In-vitro study. The noise levels of two contemporary HFNC devices (Fisher & Paykel NHF™ and Vapotherm Precision Flow®) and one CPAP device (Dräger Babylog® 8000 plus) were measured in the oral cavity of a newborn manikin in an incubator in a quiet environment. HFNC flows of 4-8 l/min and CPAP pressures of 4-8 cm H2O were applied. The CPAP flow was set at 8 l/min as per unit practice. Vapotherm HFNC generated the highest noise levels, measuring 81.2-91.4 dB(A) with increasing flow. Fisher & Paykel HFNC noise levels were between 78.8 and 81.2 dB(A). The CPAP device generated the lowest noise levels between 73.9 and 77.4 dB(A). Both HFNC devices generated higher noise levels than the CPAP device. All noise levels were far above current recommendations of the American Academy of Pediatrics. In light of the long duration of non-invasive respiratory support of very preterm infants, less noisy devices are required to prevent the potentially adverse effects of continuing excessive noise exposure in the neonatal intensive care unit. Copyright © 2013 S. Karger AG, Basel.

High-dose phenobarbital with intermittent short-acting barbiturates for acute encephalitis with refractory, repetitive partial seizures.

PubMed

Uchida, Takashi; Takayanagi, Masaru; Kitamura, Taro; Nishio, Toshiyuki; Numata, Yurika; Endo, Wakaba; Haginoya, Kazuhiro; Ohura, Toshihiro

2016-08-01

Acute encephalitis with refractory, repetitive partial seizures (AERRPS) is characterized by repetitive seizures during the acute and chronic phases and has a poor neurological outcome. Burst-suppression coma via continuous i.v. infusion of a short-acting barbiturate is used to terminate refractory seizures, but the severe side-effects of short-acting barbiturates are problematic. We report on a 9-year-old boy with AERRPS who was effectively treated with very-high-dose phenobarbital (VHDPB) combined with intermittent short-acting barbiturates. VHDPB side-effects were mild, especially compared with those associated with continuous i.v. infusion of short-acting barbiturates (dosage, 40-75 mg/kg/day; maximum blood level, 290 μg/mL). Using VHDPB as the main treatment, short-acting barbiturates were used intermittently and in small amounts. This is the first report to show that VHDPB, combined with intermittent short-acting barbiturates, can effectively treat AERRPS. After treatment, convulsions were suppressed and daily life continued, but intellectual impairment and high-level dysfunction remained. © 2016 Japan Pediatric Society.

Biomarkers From Late Pregnancy to 6 Weeks Postpartum in HIV-Infected Women Who Continue Versus Discontinue Antiretroviral Therapy After Delivery

PubMed Central

Hoffman, Risa M.; Leister, Erin; Kacanek, Deborah; Shapiro, David E.; Read, Jennifer S.; Bryson, Yvonne; Currier, Judith S.

2013-01-01

Background Women who use antiretroviral therapy (ART) solely for the prevention of mother-to-child transmission of HIV discontinue postpartum. We hypothesized that women discontinuing ART by 6 weeks postpartum (“discontinuers”) would have elevated postpartum inflammatory biomarker levels relative to women remaining on ART postpartum (“continuers”). Methods Data from HIV-infected pregnant women enrolled in the International Maternal Pediatric Adolescent AIDS Clinical Trials Group P1025 with CD4 counts >350 cells per cubic millimeter before initiating ART or first pregnancy CD4 counts >400 cells per cubic millimeter after starting ART and with available stored plasma samples at >20 weeks of gestation, delivery, and 6 weeks postpartum were analyzed. Plasma samples were tested for highly sensitive C-reactive protein, D-dimer, and interleukin-6. We used longitudinal linear spline regression to model biomarkers over time. Results Data from 128 women (65 continuers and 63 discontinuers) were analyzed. All biomarkers increased from late pregnancy to delivery, then decreased postpartum (slopes different from 0, P < 0.001). Continuers had a steeper decrease in log D-dimer between delivery and 6 weeks postpartum than discontinuers (P = 0.002). Conclusions In contrast to results from treatment interruption studies in adults, both ART continuers and ART discontinuers had significant decreases in the levels of D-dimer, highly sensitive C-reactive protein, or interleukin-6 postpartum. Continuation was associated with a more rapid decline in D-dimer levels compared with discontinuation. PMID:23714738

Advanced dendritic web growth development and development of single-crystal silicon dendritic ribbon and high-efficiency solar cell program

NASA Technical Reports Server (NTRS)

Duncan, C. S.; Seidensticker, R. G.; Mchugh, J. P.; Hopkins, R. H.

1986-01-01

Efforts to demonstrate that the dendritic web technology is ready for commercial use by the end of 1986 continues. A commercial readiness goal involves improvements to crystal growth furnace throughput to demonstrate an area growth rate of greater than 15 sq cm/min while simultaneously growing 10 meters or more of ribbon under conditions of continuous melt replenishment. Continuous means that the silicon melt is being replenished at the same rate that it is being consumed by ribbon growth so that the melt level remains constant. Efforts continue on computer thermal modeling required to define high speed, low stress, continuous growth configurations; the study of convective effects in the molten silicon and growth furnace cover gas; on furnace component modifications; on web quality assessments; and on experimental growth activities.

Improved multi-level capability in Si3N4-based resistive switching memory using continuous gradual reset switching

NASA Astrophysics Data System (ADS)

Kim, Sungjun; Park, Byung-Gook

2017-01-01

In this letter, we compare three different types of reset switching behavior in a bipolar resistive random-access memory (RRAM) system that is housed in a Ni/Si3N4/Si structure. The abrupt, step-like gradual and continuous gradual reset transitions are largely determined by the low-resistance state (LRS). For abrupt reset switching, the large conducting path shows ohmic behavior or has a weak nonlinear current-voltage (I-V) characteristics in the LRS. For gradual switching, including both the step-like and continuous reset types, trap-assisted direct tunneling is dominant in the low-voltage regime, while trap-assisted Fowler-Nordheim tunneling is dominant in the high-voltage regime, thus causing nonlinear I-V characteristics. More importantly, we evaluate the multi-level capabilities of the two different gradual switching types, including both step-like and continuous reset behavior, using identical and incremental voltage conditions. Finer control of the conductance level with good uniformity is achieved in continuous gradual reset switching when compared to that in step-like gradual reset switching. For continuous reset switching, a single conducting path, which initially has a tunneling gap, gradually responds to pulses with even and identical amplitudes, while for step-like reset switching, the multiple conducting paths only respond to incremental pulses to obtain effective multi-level states.

Analysis of High Plains Resource Risk and Economic Impacts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tidwell, Vincent C.; Vargas, Vanessa N; Jones, Shannon M

2016-04-01

The importance of the High Plains Aquifer is broadly recognized as is its vulnerability to continued overuse. T his study e xplore s how continued depletions of the High Plains Aquifer might impact both critical infrastructure and the economy at the local, r egional , and national scale. This analysis is conducted at the county level over a broad geographic region within the states of Kansas and Nebraska. In total , 140 counties that overlie the High Plains Aquifer in these two states are analyzed. The analysis utilizes future climate projections to estimate crop production. Current water use and managementmore » practices are projected into the future to explore their related impact on the High Plains Aquifer , barring any changes in water management practices, regulat ion, or policy. Finally, the impact of declining water levels and even exhaustion of groundwater resources are projected for specific sectors of the economy as well as particular elements of the region's critical infrastructure.« less

Robust continuous clustering

PubMed Central

Shah, Sohil Atul

2017-01-01

Clustering is a fundamental procedure in the analysis of scientific data. It is used ubiquitously across the sciences. Despite decades of research, existing clustering algorithms have limited effectiveness in high dimensions and often require tuning parameters for different domains and datasets. We present a clustering algorithm that achieves high accuracy across multiple domains and scales efficiently to high dimensions and large datasets. The presented algorithm optimizes a smooth continuous objective, which is based on robust statistics and allows heavily mixed clusters to be untangled. The continuous nature of the objective also allows clustering to be integrated as a module in end-to-end feature learning pipelines. We demonstrate this by extending the algorithm to perform joint clustering and dimensionality reduction by efficiently optimizing a continuous global objective. The presented approach is evaluated on large datasets of faces, hand-written digits, objects, newswire articles, sensor readings from the Space Shuttle, and protein expression levels. Our method achieves high accuracy across all datasets, outperforming the best prior algorithm by a factor of 3 in average rank. PMID:28851838

Winter Thaws Can Raise Ground Water Levels in Driftless Area

Treesearch

Richard S. Sartz

1967-01-01

Springflow and ground water levels both rose with winter thaws, even when the ground was frozen. A high soil water content suggests that water moved to the water table through a continuous column of soil water rather than as a wetting front

Final report on cermet high-level waste forms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kobisk, E.H.; Quinby, T.C.; Aaron, W.S.

1981-08-01

Cermets are being developed as an alternate method for the fixation of defense and commercial high level radioactive waste in a terminal disposal form. Following initial feasibility assessments of this waste form, consisting of ceramic particles dispersed in an iron-nickel base alloy, significantly improved processing methods were developed. The characterization of cermets has continued through property determinations on samples prepared by various methods from a variety of simulated and actual high-level wastes. This report describes the status of development of the cermet waste form as it has evolved since 1977. 6 tables, 18 figures.

The effects of control field detuning on the modulation instability in a three-level quantum well system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borgohain, Nitu, E-mail: nituborgohain.ism@gmail.com; Konar, S.

The paper presents a theoretical study of the modulation instability of a continuous or quasi-continuous optical probe in a three level quantum well system under electromagnetically induced transparency. The modulation instability is affected by the control field detuning, as well as even-order dispersion and by the strength of Kerr (third-order) and quintic (fifth-order) nonlinearities. The fourth-order dispersion reduces the bandwidth over which modulation instability occurs, whereas the quintic nonlinearity saturates the growth of the modulation instability. Detuning the control field from resonance can significantly reduce the growth of the modulation instability at both low and high power levels. At lowmore » powers, the system becomes stable against modulation instability for small detuning of the control field and at high powers modulation instability disappears for larger detuning.« less

Occupational burnout and work factors in community and hospital midwives: a survey analysis.

PubMed

Yoshida, Yukiko; Sandall, Jane

2013-08-01

community-based midwifery practice has been promoted in the UK maternity policy over the last decade as a means of increasing continuity of care. However, there have been growing concerns to suggest that the community-based continuity model may not be sustainable due to the high levels of occupational burnout in midwives resulted by increased on-call work. this paper attempted to identify work factors associated with the levels of burnout in community midwives as compared to hospital midwives, aiming at contributing to the debate of organising sustainable midwifery care. a statistical analysis was conducted drawing on data from a survey of all midwives working at one Hospital Trust in England (n=238). Occupational burnout was measured using the Maslach Burnout Inventory (MBI). the sample midwives (n=128, 54%) had significantly higher levels of burnout compared to the reference groups. Multiple regression analysis identified as follows: (1) high levels of occupational autonomy were a key protective factor of burnout, and more prevalent in the community, (2) working hours were positively associated with burnout, and community midwives were more likely to have higher levels of stress recognition, and (3) support for work-life-balance from the Trust had a significant protective effect on the levels of burnout. the results should be taken into account in the maternity policy in order to incorporate continuity of care and sustainable organisation of midwifery care. Copyright © 2012 Elsevier Ltd. All rights reserved.

14 CFR 23.203 - Turning flight and accelerated turning stalls.

Code of Federal Regulations, 2012 CFR

2012-01-01

... § 23.201(b), it must be possible to regain wings level flight by normal use of the flight controls, but... percent of maximum continuous power results in extreme nose-up attitudes, the test may be carried out with..., if the power-to-weight ratio at 75 percent of maximum continuous power results in nose-high attitudes...

Correlational Study of Project Managers' Competence Experience, Education, and Technology Experience on Project

ERIC Educational Resources Information Center

Hosford, Bryan

2017-01-01

Organizations continue to rely on information technology (IT) as a foundational element, yet poor IT project success continues to impact growth and innovation. Research into IT project success is widespread yet has focused on high-level project management attributes, not specific IT solutions. A review of the research literature revealed that the…

A modular cage system design for continuous medium to large scale in vivo-rearing of predatory mites (Acari: phytoseiidae)

USDA-ARS?s Scientific Manuscript database

A new stackable modular system was developed for continuous in-vivo production of phytoseiid mites. The system consists of cage units that are filled with lima bean, Phaseolus lunatus, or red beans, P. vulgaris, leaves infested with high levels of the two-spotted spider mites, Tetranychus urticae. T...

Engaging in and with Research to Improve STEM Education

ERIC Educational Resources Information Center

Christodoulou, Andri

2017-01-01

The demand for students to continue studying STEM subjects at post-16 and higher education levels remains high. Since the curriculum reforms in Science and Mathematics across phases in England were initiated in 2014, uncertainty remains on the impact that these reforms will have on students and teachers as the reforms continue to be implemented…

ESSA Offers Changes That Can Continue Learning Gains

ERIC Educational Resources Information Center

Chenoweth, Karin

2016-01-01

The Every Student Succeeds Act (ESSA) gives educators a fresh opportunity to think through how to ensure that all students achieve at high levels, especially kids from low-income families and kids of color. The new law continues with four principles that had been in earlier iterations, all of which have important implications for students from…

Decreasing the complications of renal osteodystrophy secondary to high phosphorus levels by using an innovative self-monitoring educational program.

PubMed

Zagaroli, A M; Zimmer, S M; Bowes, J M; Hartley, K S

1995-01-01

We wanted continuous ambulatory peritoneal dialysis (CAPD) and continuous cycling peritoneal dialysis (CCPD) patients to become more cognitive of the complications of high-serum phosphorus levels (> 6.0 mg/dL). The phosphorus self-monitoring program was designed to encourage patients to be more responsible for preventing the complications of renal osteodystrophy. Patients' phosphorus levels were graphed monthly on a poster in the exam room. Additional posters discussed their responsibilities to control phosphorus and the complications associated with hyperphosphatemia. All patients received an informative letter regarding the inception of the program in March 1994 and also were assured total anonymity of their laboratory results. At monthly clinic appointments, they received additional written information on phosphorus and discussed their phosphorus levels. Our teaching method proved effective in our CAPD/CCPD population. In March 1994, 31% of our patients had a phosphorus level greater than 6.0 mg/dL versus 10% in September 1994. The ability of patients to see their monthly progress and the comparison with other patients encouraged much interest and questions regarding phosphorus control.

High-flow nasal prong oxygen therapy or nasopharyngeal continuous positive airway pressure for children with moderate-to-severe respiratory distress?*.

PubMed

ten Brink, Fia; Duke, Trevor; Evans, Janine

2013-09-01

The aim of this study was to compare the use of high-flow nasal prong oxygen therapy to nasopharyngeal continuous positive airway pressure in a PICU at a tertiary hospital; to understand the safety and effectiveness of high-flow nasal prong therapy; in particular, what proportion of children require escalation of therapy, whether any bedside monitoring data predict stability or need for escalation, and complications of the therapies. This was a prospective observational study of the first 6 months after the introduction of high-flow nasal prong oxygen therapy at the Royal Children's Hospital in Melbourne. Data were collected on all children who were managed with either high-flow nasal prong oxygen therapy or nasopharyngeal continuous positive airway pressure. The mode of respiratory support was determined by the treating medical staff. Data were collected on each patient before the use of high-flow nasal prong or nasopharyngeal continuous positive airway pressure, at 2 hours after starting the therapy, and the children were monitored and data collected until discharge from the ICU. Therapy was considered to be escalated if children on high-flow nasal prong required a more invasive form or higher level of respiratory support, including nasopharyngeal continuous positive airway pressure or mask bilevel positive airway pressure or endotracheal intubation and mechanical ventilation. Therapy was considered to be escalated if children on nasopharyngeal continuous positive airway pressure required bilevel positive airway pressure or intubation and mechanical ventilation. As the first mode of respiratory support, 72 children received high-flow nasal prong therapy and 37 received nasopharyngeal continuous positive airway pressure. Forty-four patients (61%) who received high-flow nasal prong first were weaned to low-flow oxygen or to room air and 21 (29%) required escalation of respiratory support, compared with children on nasopharyngeal continuous positive airway pressure: 21 (57%) weaned successfully and 9 (24%) required escalation. Repeated treatment and crossover were common in this cohort. Throughout the study duration, escalation to a higher level of respiratory support was needed in 26 of 100 high-flow nasal prong treatment episodes (26%) and in 10 of 55 continuous positive airway pressure episodes (18%; p = 0.27). The need for escalation could be predicted by two of failure of normalization of heart rate and respiratory rate, and if the FIO2 did not fall to lower than 0.5, 2 hours after starting high-flow nasal prong therapy. Nasopharyngeal continuous positive airway pressure was required for significantly longer periods than high-flow nasal prong (median 48 and 18 hours, respectively; p ≤ 0.001). High-flow nasal prong therapy is a safe form of respiratory support for children with moderate-to-severe respiratory distress, across a large range of diagnoses, whose increased work of breathing or hypoxemia is not relieved by standard oxygen therapy. About one quarter of all children will require escalation to another form of respiratory support. This can be predicted by simple bedside observations.

Auditory evoked functions in ground crew working in high noise environment of Mumbai airport.

PubMed

Thakur, L; Anand, J P; Banerjee, P K

2004-10-01

The continuous exposure to the relatively high level of noise in the surroundings of an airport is likely to affect the central pathway of the auditory system as well as the cognitive functions of the people working in that environment. The Brainstem Auditory Evoked Responses (BAER), Mid Latency Response (MLR) and P300 response of the ground crew employees working in Mumbai airport were studied to evaluate the effects of continuous exposure to high level of noise of the surroundings of the airport on these responses. BAER, P300 and MLR were recorded by using a Nicolet Compact-4 (USA) instrument. Audiometry was also monitored with the help of GSI-16 Audiometer. There was a significant increase in the peak III latency of the BAER in the subjects exposed to noise compared to controls with no change in their P300 values. The exposed group showed hearing loss at different frequencies. The exposure to the high level of noise caused a considerable decline in the auditory conduction upto the level of the brainstem with no significant change in conduction in the midbrain, subcortical areas, auditory cortex and associated areas. There was also no significant change in cognitive function as measured by P300 response.

Science Books & Films, Volume XIV, Number 1.

ERIC Educational Resources Information Center

Finch, Shari, Ed.

This document presents a continuation of the American Association for the Advancement of Science (AAAS) review of science films and books. Each book or film review includes: grade level, the level of recommendation from "Highly recommended" to "Not recommended," bibliographic data, and ordering information. A special section is…

TOPEX/El Niño Watch - Pacific Ocean Conditions are Split: Cold in East, Hot in West, July 27, 1999

NASA Image and Video Library

1999-08-23

The North Pacific Ocean continues to run hot and cold, with abnormally low sea levels and cool waters in the northeastern Pacific contrasting with unusually high sea levels and warm waters in the northwestern Pacific.

High-speed continuous-variable quantum key distribution without sending a local oscillator.

PubMed

Huang, Duan; Huang, Peng; Lin, Dakai; Wang, Chao; Zeng, Guihua

2015-08-15

We report a 100-MHz continuous-variable quantum key distribution (CV-QKD) experiment over a 25-km fiber channel without sending a local oscillator (LO). We use a "locally" generated LO and implement with a 1-GHz shot-noise-limited homodyne detector to achieve high-speed quantum measurement, and we propose a secure phase compensation scheme to maintain a low level of excess noise. These make high-bit-rate CV-QKD significantly simpler for larger transmission distances compared with previous schemes in which both LO and quantum signals are transmitted through the insecure quantum channel.

Ring laser having an output at a single frequency

DOEpatents

Hackell, Lloyd A.

1991-01-01

A ring laser is disclosed that produces a single frequency of laser radiation in either the pulsed mode of operation or the continuous waveform (cw) mode of operation. The laser comprises a ring laser in a bowtie configuration, a birefringent gain material such as Nd:YLF, an improved optical diode that supports laser oscillation having a desired direction of travel and linear polarization, and a Q-switch. An output coupler (mirror) having a high reflectivity, such as 94%, is disclosed. Also disclosed is a self-seeded method of operation in which the laser can provide a pulse or a series of pulses of high power laser radiation at a consistent single frequency with a high degree of amplitude stability and temporal stability. In operation, the laser is operated in continuous waveform (cw) at a low power output with the Q-switch introducing a loss into the resonating cavity. Pumping is continued at a high level, causing the gain material to store energy. When a pulse is desired, the Q-switch is actuated to substantially reduce the losses so that a pulse can build up based on the low level cw oscillation. The pulse quickly builds, using the stored energy in the gain medium to provide a high power output pulse. The process may be repeated to provide a series of high power pulses of a consistent single frequency.

A Case of High School Hazing: Applying Restorative Justice to Promote Organizational Learning

ERIC Educational Resources Information Center

DeWitt, Douglas M.; DeWitt, Lori J.

2012-01-01

While collegiate fraternity and sorority hazing are well documented problems that receive prominent attention, hazing at the high school level is also a serious issue. Across the nation, media headlines offer a continual reminder that high school hazing is not a phenomenon of the past. As high school principals seek ways to discourage and…

High Incubation Temperature and Threonine Dietary Level Improve Ileum Response Against Post-Hatch Salmonella Enteritidis Inoculation in Broiler Chicks

PubMed Central

de Oliveira, Heraldo Bezerra; Campos, Danila Barreiro; Guerra, Ricardo Romão; Costa, Fernando Guilherme Perazzo

2015-01-01

This study assessed the effect of both embryonic thermal manipulation and dietary threonine level on the response of broilers inoculated with Salmonella Enteritidis, considering bacterial counts in the cecal contents, intestinal morphology, mucin and heat shock protein 70 gene expression, body weight and weight gain. Thermal manipulation was used from 11 days of incubation until hatch, defining three treatments: standard (37.7°C), continuous high temperature (38.7°C) and continuous low temperature (36.7°C). After hatch, chicks were distributed according to a 3x2+1 factorial arrangement (three temperatures and two threonine levels and one sham-inoculated control). At two days of age, all chicks were inoculated with Salmonella Enteritidis, except for the sham-inoculated control group. There was no interaction between the factors on any analyses. High temperature during incubation was able to reduce colonization by Salmonella Enteritidis in the first days, reducing both Salmonella counts and the number of positive birds. It also increased mucin expression and decreased Hsp70 expression compared with other inoculated groups. High temperature during incubation and high threonine level act independently to reduce the negative effects associated to Salmonella Enteritidis infection on intestinal morphology and performance, with results similar to sham-inoculated birds. The findings open new perspectives for practical strategies towards the pre-harvest Salmonella control in the poultry industry. PMID:26131553

Continuous 28-day iododeoxyuridine infusion and hyperfractionated accelerated radiotherapy for malignant glioma: a phase I clinical study.

PubMed

Schulz, Craig A; Mehta, Minesh P; Badie, Benham; McGinn, Cornelius J; Robins, H Ian; Hayes, Lori; Chappell, Rick; Volkman, Jen; Binger, Kim; Arzoomanian, Rhoda; Simon, Kris; Alberti, Dona; Feierabend, Christine; Tutsch, Kendra D; Kunugi, Keith A; Wilding, George; Kinsella, Timothy J

2004-07-15

To investigate the maximal tolerated dose of a continuous 28-day iododeoxyuridine (IUdr) infusion combined with hyperfractionated accelerated radiotherapy (HART); to analyze the percentage of IUdr-thymidine replacement in peripheral granulocytes as a surrogate marker for IUdr incorporation into tumor cells; to measure the steady-state serum IUdr levels; and to assess the feasibility of continuous IUdr infusion and HART in the management of malignant glioma. Patients were required to have biopsy-proven malignant glioma. Patients received 100 (n = 4), 200 (n = 3), 300 (n = 3), 400 (n = 6), 500 (n = 4), 625 (n = 5), or 781 (n = 6) mg/m(2)/d of IUdr by continuous infusion for 28 days. HART was started 7 days after IUdr initiation. The total dose was 70 Gy (1.2 Gy b.i.d. for 25 days with a 10-Gy boost [2.0 Gy for 5 Saturdays]). Weekly assays were performed to determine the percentage of IUdr-DNA replacement in granulocytes and serum IUdr levels using standard high performance liquid chromatography methods. Standard Phase I toxicity methods were used. Between June 1994 and August 1999, 31 patients were enrolled. No patient had Grade 3 or worse HART toxicity. Grade 3 or greater IUdr toxicity predominantly included neutropenia (n = 3), thrombocytopenia (n = 3), and elevated liver function studies (n = 3). The maximal tolerated dose was 625 mg/m(2)/d. Thymidine replacement in the peripheral granulocytes peaked at 3 weeks and increased with the dose (maximal thymidine replacement 4.9%). The steady-state plasma IUdr level increased with the dose (maximum, 1.5 microM). In our study, continuous long-term IUdr i.v. infusion had a maximal tolerated dose of 625 mg/m(2)/d. Granulocyte incorporation data verified the concept that prolonged IUdr infusion results in IUdr-DNA replacement that corresponds to a high degree of cell labeling. IUdr steady-state plasma levels increased with increasing dose and attained levels needed for clinical radiosensitization. Continuous IUdr infusion and HART were both feasible and well tolerated.

Continuous high speed coherent one-way quantum key distribution.

PubMed

Stucki, Damien; Barreiro, Claudio; Fasel, Sylvain; Gautier, Jean-Daniel; Gay, Olivier; Gisin, Nicolas; Thew, Rob; Thoma, Yann; Trinkler, Patrick; Vannel, Fabien; Zbinden, Hugo

2009-08-03

Quantum key distribution (QKD) is the first commercial quantum technology operating at the level of single quanta and is a leading light for quantum-enabled photonic technologies. However, controlling these quantum optical systems in real world environments presents significant challenges. For the first time, we have brought together three key concepts for future QKD systems: a simple high-speed protocol; high performance detection; and integration both, at the component level and for standard fibre network connectivity. The QKD system is capable of continuous and autonomous operation, generating secret keys in real time. Laboratory and field tests were performed and comparisons made with robust InGaAs avalanche photodiodes and superconducting detectors. We report the first real world implementation of a fully functional QKD system over a 43 dB-loss (150 km) transmission line in the Swisscom fibre optic network where we obtained average real-time distribution rates over 3 hours of 2.5 bps.

Generalized predictive control for a coupled four tank MIMO system using a continuous-discrete time observer.

PubMed

Gouta, Houssemeddine; Hadj Saïd, Salim; Barhoumi, Nabil; M'Sahli, Faouzi

2017-03-01

This paper deals with the problem of the observer based control design for a coupled four-tank liquid level system. For this MIMO system's dynamics, motivated by a desire to provide precise and sensorless liquid level control, a nonlinear predictive controller based on a continuous-discrete observer is presented. First, an analytical solution from the model predictive control (MPC) technique is developed for a particular class of nonlinear MIMO systems and its corresponding exponential stability is proven. Then, a high gain observer that runs in continuous-time with an output error correction time that is updated in a mixed continuous-discrete fashion is designed in order to estimate the liquid levels in the two upper tanks. The effectiveness of the designed control schemes are validated by two tests; The first one is maintaining a constant level in the first bottom tank while making the level in the second bottom tank to follow a sinusoidal reference signal. The second test is more difficult and it is made using two trapezoidal reference signals in order to see the decoupling performance of the system's outputs. Simulation and experimental results validate the objective of the paper. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

Examining Spillovers between Long and Short Repeated Prisoner's Dilemma Games Played in the Laboratory.

PubMed

Arechar, Antonio A; Kouchaki, Maryam; Rand, David G

2018-03-01

We had participants play two sets of repeated Prisoner's Dilemma (RPD) games, one with a large continuation probability and the other with a small continuation probability, as well as Dictator Games (DGs) before and after the RPDs. We find that, regardless of which is RPD set is played first, participants typically cooperate when the continuation probability is large and defect when the continuation probability is small. However, there is an asymmetry in behavior when transitioning from one continuation probability to the other. When switching from large to small, transient higher levels of cooperation are observed in the early games of the small continuation set. Conversely, when switching from small to large, cooperation is immediately high in the first game of the large continuation set. We also observe that response times increase when transitioning between sets of RPDs, except for altruistic participants transitioning into the set of RPDs with long continuation probabilities. These asymmetries suggest a bias in favor of cooperation. Finally, we examine the link between altruism and RPD play. We find that small continuation probability RPD play is correlated with giving in DGs played before and after the RPDs, whereas high continuation probability RPD play is not.

A Dynamic Interactive Theory of Person Construal

ERIC Educational Resources Information Center

Freeman, Jonathan B.; Ambady, Nalini

2011-01-01

A dynamic interactive theory of person construal is proposed. It assumes that the perception of other people is accomplished by a dynamical system involving continuous interaction between social categories, stereotypes, high-level cognitive states, and the low-level processing of facial, vocal, and bodily cues. This system permits lower-level…

Patient-reported care coordination: associations with primary care continuity and specialty care use.

PubMed

Liss, David T; Chubak, Jessica; Anderson, Melissa L; Saunders, Kathleen W; Tuzzio, Leah; Reid, Robert J

2011-01-01

Care coordination is increasingly recognized as a necessary element of high-quality, patient-centered care. This study investigated (1) the association between care coordination and continuity of primary care, and (2) differences in this association by level of specialty care use. We conducted a cross-sectional study of Medicare enrollees with select chronic conditions in an integrated health care delivery system in Washington State. We collected survey information on patient experiences and automated health care utilization data for 1 year preceding survey completion. Coordination was defined by the coordination measure from the short form of the Ambulatory Care Experiences Survey (ACES). Continuity was measured by primary care visit concentration. Patients who had 10 or more specialty care visits were classified as high users. Linear regression was used to estimate the association between coordination and continuity, controlling for potential confounders and clustering within clinicians. We used a continuity-by-specialty interaction term to determine whether the continuity-coordination association was modified by high specialty care use. Among low specialty care users, an increase of 1 standard deviation (SD) in continuity was associated with an increase of 2.71 in the ACES coordination scale (P <.001). In high specialty care users, we observed no association between continuity and reported coordination (P= .77). High use of specialty care may strain the ability of primary care clinicians to coordinate care effectively. Future studies should investigate care coordination interventions that allow for appropriate specialty care referrals without diminishing the ability of primary care physicians to manage overall patient care.

Teaching Physics in English: A Continuing Professional Development for Non-Native English-Speaking Teachers in Thailand

ERIC Educational Resources Information Center

Pruekpramool, Chaninan; Sangpradit, Theerapong

2016-01-01

The purposes of this study were to develop a Continuing Professional Development (CPD) using English integrated science approach training curriculum and to promote physics teacher's efficacy to be expert teachers and be able to teach Physics in English. The quality of the curriculum was at a high level corresponding to the congruence scores of the…

Impact of construction and remodeling markets on the U.S. secondary hardwood products industry

Treesearch

Matt Bumgardner; Urs Buehlmann; Al Schuler; Karen Koenig

2011-01-01

The housing correction that started in 2007 continues to run its course. Excessive inventory levels, limited credit availability, and record foreclosure rates continue to have an impact on U.S. housing markets. With inventories high and demand for new construction low, the U.S. hardwood industry's largest markets for appearance-grade products remain under pressure...

The Learning Intention of Low-Qualified Employees: A Key for Participation in Lifelong Learning and Continuous Training

ERIC Educational Resources Information Center

Kyndt, Eva; Govaerts, Natalie; Dochy, Filip; Baert, Herman

2011-01-01

In our continuously changing society, a need for updating one's skills and knowledge puts pressure on safeguarding the labour market position of low-qualified employees. However, prior research and official statistics show that employees with a lower level of education tend to participate less in training than highly-educated individuals. This…

California's Youth and Young Adult Arrest Rates Continue a Historic Decline. Fact Sheet

ERIC Educational Resources Information Center

Males, Mike

2016-01-01

This Center on Juvenile and Criminal Justice (CJCJ) fact sheet shows that, in 2015, arrests of young people under age 25 dropped below 2014 levels and continue a decades-long trend of decline. While the causes of these declines are unknown, falling youth arrests rates coupled with decreased youth incarceration suggest that high rates of…

Process Development for Hydrothermal Liquefaction of Algae Feedstocks in a Continuous-Flow Reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elliott, Douglas C.; Hart, Todd R.; Schmidt, Andrew J.

Wet algae slurries can be converted into an upgradeable biocrude by hydrothermal liquefaction (HTL). High levels of carbon conversion to gravity-separable biocrude product were accomplished at relatively low temperature (350 °C) in a continuous-flow, pressurized (sub-critical liquid water) environment (20 MPa). As opposed to earlier work in batch reactors reported by others, direct oil recovery was achieved without the use of a solvent and biomass trace components were removed by processing steps so that they did not cause process difficulties. High conversions were obtained even with high slurry concentrations of up to 35 wt% of dry solids. Catalytic hydrotreating wasmore » effectively applied for hydrodeoxygenation, hydrodenitrogenation, and hydrodesulfurization of the biocrude to form liquid hydrocarbon fuel. Catalytic hydrothermal gasification was effectively applied for HTL byproduct water cleanup and fuel gas production from water soluble organics, allowing the water to be considered for recycle of nutrients to the algae growth ponds. As a result, high conversion of algae to liquid hydrocarbon and gas products was found with low levels of organic contamination in the byproduct water. All three process steps were accomplished in bench-scale, continuous-flow reactor systems such that design data for process scale-up was generated.« less

Reducing environmental risk of excessively fertilized soils and improving cucumber growth by Caragana microphylla-straw compost application in long-term continuous cropping systems.

PubMed

Tian, Yongqiang; Wang, Qing; Zhang, Weihua; Gao, Lihong

2016-02-15

Continuous cropping is a common agricultural practice in the word. In China, farmers often apply excessive fertilizers to fields in an attempt to maintain yields in continuous cropping systems. However, this practice often results in high nutrient concentrations in soils, nutrient pollution in leaching water and more crop disease. Here, we investigated 8 different soils from continuously cropped cucumbers in Northern China that grouped into those with extremely high nutrient levels (EHNL) and those with lower nutrient levels (LNL). All soils were treated with Caragana microphylla-straw (CMS) compost addition, and then were used to measure soil physiochemical and microbial properties, leaching water quality, plant root growth and cucumber fruit yield. In general, the EHNL-soil showed higher nitrate, phosphorus and potassium concentrations in the leaching water compared to the LNL-soil. However, the CMS compost application increased soil nutrient and water holding capacities, total microbial biomass (bacteria and fungi), root length, plant biomass and fruit yields, but decreased nutrient concentrations in the leaching water from the EHNL-soil. In addition, the CMS compost decreased the number of Fusarium oxysporum f. sp. cucumerinum in soils with very high concentration of mineral nitrogen. Our results infer that CMS compost application was an effective method for reducing environmental risk of excessively fertilized soils. Copyright © 2015 Elsevier B.V. All rights reserved.

Gender and grade level differences in interest, perceived personal capacity, and involvement in technology and engineering-related activities

NASA Astrophysics Data System (ADS)

Weber, Katherine

Society has become increasingly technological, demanding that all citizens have a level of technological literacy. In order for this to occur, both males and females must participate in technology-related activities to achieve an adequate level of technological literacy. Despite individual and organizational efforts, females continue to be underrepresented in STEM-related occupations. This is especially true in many engineering-related fields. Jolly, Campbell and Perlman (2004) devised the Engagement, Capacity, and Continuity (ECC) Trilogy. With each factor of the trilogy in place, Jolly et al. found that female representation increased in STEM. The purpose of this study was to identify whether Jolly, Campbell, and Perlman's (2004) Engagement, Capacity, and Continuity Trilogy could be utilized by teachers in technology and engineering program settings to examine their students' interest (engagement), perceived personal capacity (capacity), as well as participation in technology and engineering-related activities (continuity). This descriptive study surveyed 556 female and male middle school and high school students enrolled in Technology and Engineering classes. The results of this study revealed that when students indicated a high interest and a high perceived personal capacity, and when they participated in technology and engineering-related activities, they also indicated an interest in pursuing a career in engineering. The results also revealed that the male students continued to be encouraged by technology and engineering teachers, parents, and counselors to pursue a career in engineering more than female students. This startling finding should draw some concern; both males and females should be equally encouraged to consider engineering as a career. Technology and engineering teachers should implement activities that appeal to both males and females. Parents should encourage their daughters to participate in informal learning opportunities to nurture their daughters' interest in STEM-related areas. Counselors should gain an awareness of the scope and diversity of different engineering fields so they can advise both male and female students to consider careers in engineering. In order for the United States to be competitive and innovative at the global level, female representation and contributions in STEM fields must increase. Key Words: GENDER, ENGAGEMENT, INTEREST, PERCEIVED PERSONAL CAPACITY, TECHNOLOGY AND ENGINEERING ACTIVITIES, WISCONSIN, STEM, AFTERSCHOOL ACTIVITIES.

High-sensitivity, high-speed continuous imaging system

DOEpatents

Watson, Scott A; Bender, III, Howard A

2014-11-18

A continuous imaging system for recording low levels of light typically extending over small distances with high-frame rates and with a large number of frames is described. Photodiode pixels disposed in an array having a chosen geometry, each pixel having a dedicated amplifier, analog-to-digital convertor, and memory, provide parallel operation of the system. When combined with a plurality of scintillators responsive to a selected source of radiation, in a scintillator array, the light from each scintillator being directed to a single corresponding photodiode in close proximity or lens-coupled thereto, embodiments of the present imaging system may provide images of x-ray, gamma ray, proton, and neutron sources with high efficiency.

Exercise training in adults with repaired tetralogy of Fallot: A randomized controlled pilot study of continuous versus interval training.

PubMed

Novaković, Marko; Prokšelj, Katja; Rajkovič, Uroš; Vižintin Cuderman, Tjaša; Janša Trontelj, Katja; Fras, Zlatko; Jug, Borut

2018-03-15

Adults with repaired tetralogy of Fallot (ToF) have impaired exercise capacity, vascular and cardiac autonomic function, and quality of life (QoL). Specific effects of high-intensity interval or moderate continuous exercise training on these parameters in adults with repaired ToF remain unknown. Thirty adults with repaired ToF were randomized to either high-intensity interval, moderate intensity continuous training (36 sessions, 2-3 times a week) or usual care (no supervised exercise). Exercise capacity, flow-mediated vasodilation, pulse wave velocity, NT-proBNP and fibrinogen levels, heart rate variability and recovery, and QoL (SF-36 questionnaire) were determined at baseline and after the intervention period. Twenty-seven patients (mean age 39±9years, 63% females, 9 from each group) completed this pilot study. Both training groups improved in at least some parameters of cardiovascular health compared to no exercise. Interval-but not continuous-training improved VO2peak (21.2 to 22.9ml/kg/min, p=0.004), flow-mediated vasodilation (8.4 to 12.9%, p=0.019), pulse wave velocity (5.4 to 4.8m/s, p=0.028), NT-proBNP (202 to 190ng/L, p=0.032) and fibrinogen levels (2.67 to 2.46g/L, p=0.018). Conversely, continuous-but not interval-training improved heart rate variability (low-frequency domain, 0.32 to 0.22, p=0.039), heart rate recovery after 2min post-exercise (40 to 47 beats, p=0.023) and mental domain of SF-36 (87 to 95, p=0.028). Both interval and continuous exercise training modalities were safe. Interval training seems more efficacious in improving exercise capacity, vascular function, NT-proBNP and fibrinogen levels, while continuous training seems more efficacious in improving cardiac autonomic function and QoL. (Clinicaltrials.gov, NCT02643810). Copyright © 2018 Elsevier Ireland Ltd. All rights reserved.

Integrated injection-locked semiconductor diode laser

DOEpatents

Hadley, G. Ronald; Hohimer, John P.; Owyoung, Adelbert

1991-01-01

A continuous wave integrated injection-locked high-power diode laser array is provided with an on-chip independently-controlled master laser. The integrated injection locked high-power diode laser array is capable of continuous wave lasing in a single near-diffraction limited output beam at single-facet power levels up to 125 mW (250 mW total). Electronic steering of the array emission over an angle of 0.5 degrees is obtained by varying current to the master laser. The master laser injects a laser beam into the slave array by reflection of a rear facet.

Results of an all-sky high-frequency Einstein@Home search for continuous gravitational waves in LIGO's fifth science run

NASA Astrophysics Data System (ADS)

Singh, Avneet; Papa, Maria Alessandra; Eggenstein, Heinz-Bernd; Zhu, Sylvia; Pletsch, Holger; Allen, Bruce; Bock, Oliver; Maschenchalk, Bernd; Prix, Reinhard; Siemens, Xavier

2016-09-01

We present results of a high-frequency all-sky search for continuous gravitational waves from isolated compact objects in LIGO's fifth science run (S5) data, using the computing power of the Einstein@Home volunteer computing project. This is the only dedicated continuous gravitational wave search that probes this high-frequency range on S5 data. We find no significant candidate signal, so we set 90% confidence level upper limits on continuous gravitational wave strain amplitudes. At the lower end of the search frequency range, around 1250 Hz, the most constraining upper limit is 5.0 ×10-24, while at the higher end, around 1500 Hz, it is 6.2 ×10-24. Based on these upper limits, and assuming a fiducial value of the principal moment of inertia of 1038 kg m2 , we can exclude objects with ellipticities higher than roughly 2.8 ×10-7 within 100 pc of Earth with rotation periods between 1.3 and 1.6 milliseconds.

Preliminary design of a high-intensity continuous-wave deuteron RFQ

NASA Astrophysics Data System (ADS)

Liu, X.; Kamigaito, O.; Sakamoto, N.; Yamada, K.

2017-07-01

A high-intensity deuteron linear accelerator is currently being studied as a promising candidate to treat high-level radioactive waste through the nuclear transmutation process. This paper presents the study on a design of a 75.5 MHz, 400 mA, continuous-wave deuteron radio-frequency quadrupole (RFQ), which is proposed as the front-end of such a linear accelerator. The results of the beam dynamics simulation suggest that the designed RFQ can accelerate a 400-mA deuteron beam from 100 keV to 2.5 MeV with a transmission rate of 92.0 ∼ 93.3%, depending on the assumed input transverse emittance.

Addendum to ESEA Title I Program Evaluation [Phoenix Union High School System, Arizona].

ERIC Educational Resources Information Center

Estes, Gary D.

An Elementary Secondary Education Act Title I English/Writing project was continued at two Phoenix Union high schools, Carl Hayden and North High Schools, in 1974-75. Although the objectives and instructional method (individualized, diagnostic, prescriptive approach) were the same at the two schools, the entry level skills and abilities of the…

The Influence of Principal Longevity and Continuity on Student Achievement

ERIC Educational Resources Information Center

Mills, Gemar

2017-01-01

In the state of New Jersey, academic success at the high school level is defined by student achievement on the New Jersey High School Proficiency Assessment (NJ HSPA), which students take in the 11th grade. New Jersey high school principals are accountable for ensuring that students who attend their schools are proficient in mathematics and…

Psychiatric symptoms in methamphetamine users.

PubMed

Zweben, Joan E; Cohen, Judith B; Christian, Darrell; Galloway, Gantt P; Salinardi, Michelle; Parent, David; Iguchi, Martin

2004-01-01

The Methamphetamine Treatment Project (MTP) offers the opportunity to examine co-occurring psychiatric conditions in a sample of 1016 methamphetamine users participating in a multisite outpatient treatment study between 1999-2001. Participants reported high levels of psychiatric symptoms, particularly depression and attempted suicide, but also anxiety and psychotic symptoms. They also reported high levels of problems controlling anger and violent behavior, with a correspondingly high frequency of assault and weapons charges. Findings continue to support the value of integrated treatment for co-occurring conditions, especially the importance of training counseling staff to handle psychotic symptoms when needed.

Measles: Current Status and Outbreak Control on Campus.

ERIC Educational Resources Information Center

Amler, Robert W.; Orenstein, Walter A.

1984-01-01

The current effort to eliminate measles in the United States has caused record low levels of the disease. This strategy must continue to be applied in order to break the transmission of measles on college campuses through high immunization levels, promotion of rapid reporting of cases, and quick responses to outbreaks. (Author/DF)

Rapid coupling between ice volume and polar temperature over the past 150,000 years.

PubMed

Grant, K M; Rohling, E J; Bar-Matthews, M; Ayalon, A; Medina-Elizalde, M; Ramsey, C Bronk; Satow, C; Roberts, A P

2012-11-29

Current global warming necessitates a detailed understanding of the relationships between climate and global ice volume. Highly resolved and continuous sea-level records are essential for quantifying ice-volume changes. However, an unbiased study of the timing of past ice-volume changes, relative to polar climate change, has so far been impossible because available sea-level records either were dated by using orbital tuning or ice-core timescales, or were discontinuous in time. Here we present an independent dating of a continuous, high-resolution sea-level record in millennial-scale detail throughout the past 150,000 years. We find that the timing of ice-volume fluctuations agrees well with that of variations in Antarctic climate and especially Greenland climate. Amplitudes of ice-volume fluctuations more closely match Antarctic (rather than Greenland) climate changes. Polar climate and ice-volume changes, and their rates of change, are found to covary within centennial response times. Finally, rates of sea-level rise reached at least 1.2 m per century during all major episodes of ice-volume reduction.

Breaking continuous flash suppression: competing for consciousness on the pre-semantic battlefield

PubMed Central

Gayet, Surya; Van der Stigchel, Stefan; Paffen, Chris L. E.

2014-01-01

Traditionally, interocular suppression is believed to disrupt high-level (i.e., semantic or conceptual) processing of the suppressed visual input. The development of a new experimental paradigm, breaking continuous flash suppression (b-CFS), has caused a resurgence of studies demonstrating high-level processing of visual information in the absence of visual awareness. In this method the time it takes for interocularly suppressed stimuli to breach the threshold of visibility, is regarded as a measure of access to awareness. The aim of the current review is twofold. First, we provide an overview of the literature using this b-CFS method, while making a distinction between two types of studies: those in which suppression durations are compared between different stimulus classes (such as upright faces versus inverted faces), and those in which suppression durations are compared for stimuli that either match or mismatch concurrently available information (such as a colored target that either matches or mismatches a color retained in working memory). Second, we aim at dissociating high-level processing from low-level (i.e., crude visual) processing of the suppressed stimuli. For this purpose, we include a thorough review of the control conditions that are used in these experiments. Additionally, we provide recommendations for proper control conditions that we deem crucial for disentangling high-level from low-level effects. Based on this review, we argue that crude visual processing suffices for explaining differences in breakthrough times reported using b-CFS. As such, we conclude that there is as yet no reason to assume that interocularly suppressed stimuli receive full semantic analysis. PMID:24904476

Near-optimal integration of facial form and motion.

PubMed

Dobs, Katharina; Ma, Wei Ji; Reddy, Leila

2017-09-08

Human perception consists of the continuous integration of sensory cues pertaining to the same object. While it has been fairly well shown that humans use an optimal strategy when integrating low-level cues proportional to their relative reliability, the integration processes underlying high-level perception are much less understood. Here we investigate cue integration in a complex high-level perceptual system, the human face processing system. We tested cue integration of facial form and motion in an identity categorization task and found that an optimal model could successfully predict subjects' identity choices. Our results suggest that optimal cue integration may be implemented across different levels of the visual processing hierarchy.

The Decade of the Hispanic: An Economic Retrospective.

ERIC Educational Resources Information Center

Miranda, Leticia; Quiroz, Julia Teresa

The report identifies and describes trends characterizing Hispanics' economic situation in the 1980s. It also analyzes the most significant contributions to these trends, and their public policy implications. The following trends are discussed: (1) stagnating income levels and continued high poverty; (2) high proportions of impoverished children;…

Drivers of Successful Bond and Operating Levies...Q4C at the Foundation.

ERIC Educational Resources Information Center

Lifto, Don E. Morris; Morris, William D.

2000-01-01

Improving a school's Q4C quotient (quality control, customer commitment, and communications) during election planning hinges on district mission, a culture of high expectations, basic skills mastery, commitment to customers, continuous feedback, healthy working relationships, broad community involvement, high- level strategic planning and…

Sex-Role Ideology and the Aspirations of High School Girls

ERIC Educational Resources Information Center

Gaskell, Jane

1977-01-01

Variables specifically related to sex-role definitions in our society must be considered in accounting for the generally lower aspirations of women since after controlling the variables of social class and academic achievement, sex continues to make a difference in the aspiration levels of high school girls. (MJB)

Low- and High-Resistance Exercise: Long-Term Adherence and Motivation among Older Adults.

PubMed

Van Roie, Evelien; Bautmans, Ivan; Coudyzer, Walter; Boen, Filip; Delecluse, Christophe

2015-01-01

In terms of motivation and long-term adherence, low-resistance exercise might be more suitable for older adults than high-resistance exercise. However, more data are needed to support this claim. The objective was to investigate the effect of low- and high-resistance exercise protocols on long-term adherence and motivation. This study was designed as an exploratory 24-week follow-up of a randomized 12-week resistance training intervention in older adults. Participants were free to decide whether or not they continued resistance training at their own expense following the intervention. Fifty-six older adults were randomly assigned to HIGH [2 × 10-15 repetitions at 80% of one repetition maximum (1RM)], LOW (1 × 80-100 repetitions at 20% of 1RM), or LOW+ (1 × 60 repetitions at 20% of 1RM + 1 × 10-20 repetitions at 40% 1RM). Motivation, self-efficacy and the perceived barriers for continuing resistance exercise were measured after cessation of each supervised intervention and at follow-up, while long-term adherence was probed retrospectively at follow-up. Participants reported high levels of self-determined motivation before, during, and after the supervised intervention, with no differences between groups (p > 0.05). Nevertheless, only few participants continued strength training after the intervention: 17% in HIGH, 21% in LOW+, and 11% in LOW (p > 0.05). The most commonly reported barriers for continuing resistance exercise were perceived lack of time (46%), being more interested in other physical activities (40%), seasonal reasons (40%), and financial cost (28%). The results suggest no difference in long-term adherence after the end of a supervised exercise intervention at high or low external resistances. Long-term adherence was limited despite high levels of self-determined motivation during the interventions. These findings highlight the importance of further research on developing strategies to overcome barriers of older adults to adhere to resistance exercise without supervision. © 2015 S. Karger AG, Basel.

Advanced myopia, prevalence and incidence analysis.

PubMed

Greene, Peter R; Greene, Judith M

2018-04-01

Various high-percentage high-incidence medical conditions, acute or chronic, start at a particular age of onset t1 (years), accumulate or progress rapidly, with a system time constant t0 (years), typically from 1 week to 5 years, and then level off at a plateau level [Formula: see text], ultimately affecting 10-95% of the population. This report investigates the prevalence and incidence functions for myopia and high myopia as a function of age. Fundamental prevalence versus time and incidence versus time results allow continuous prediction of myopia and high myopia population fractions as a function of age. This is a retrospective study. Nine reports are calculated with N = 444,600 subjects. There were no interventions other than usual regular eye examinations and subsequent indicated refraction change. The main result is continuous prediction of myopia prevalence-time data along with incidence rate data (%/year), age of onset (years), system plateau level, and system time constant (years). These parameters apply to progressive myopia and high myopia (R < -6 D), useful over several decades. The primary finding of this research is that the prevalence ratio of high myopes (R < -6.0 D) to common myopes is expected to increase from 15% entering college to 45% or more after college and graduate school. These statistics are particularly relevant to the many years of study required by M.D., Ph.D., and M.D./Ph.D. programs.

Changes in mortality rates and humanitarian conditions in Darfur, Sudan 2003-2007.

PubMed

Garfield, Richard; Polonsky, Jonny

2010-01-01

The Darfur region of Sudan has been an intense focus of humanitarian concern since rebellions began there early in 2003. In 2004, the US Secretary of State declared that conflict in Darfur represented genocide. Since 2003, many sample surveys and various mortality estimates for Darfur have been made. Nonetheless, confusion and controversy surrounding mortality levels and trends have continued. For this project, results were reviewed from the highest quality field surveys on mortality in Darfur conducted between 2003 and 2008. Trend analysis demonstrated a dramatic decline in mortality over time in Darfur. By 2005, mortality levels had fallen below emergency levels and have continued to decline. Deaths directly due violence have declined as a proportion of all of the deaths in Darfur. Declining mortality in Darfur was not associated with other proximate improvements in well-being, such as improved nutrition. Without large-scale, humanitarian intervention, continuing high rates of mortality due to violence likely would have occurred. If mortality had continued at the high rate documented in 2004, by January 2009, there would have been 330,000 additional deaths. With the humanitarian assistance provided through the United Nations and non-governmental organizations, these people are alive today. A focus on excess deaths among noncombatants may draw attention away from other needs, such as establishing better security, improving service delivery to the displaced, and advocating for internally displaced persons to be reached today and to re-establish their lives and livelihoods tomorrow.

Relationships among cardiovascular, muscular, and oxytocin responses during human sexual activity.

PubMed

Carmichael, M S; Warburton, V L; Dixen, J; Davidson, J M

1994-02-01

To determine the psychophysiological correlates of hormonal response during sexual activity, systolic blood pressure (SBP), anal electromyography (EMG), and anal photoplethysmography (APG) were monitored continuously throughout testing in 13 women and 10 men. Each subject completed two or more tests of self-stimulation to 5 min beyond orgasm. Blood samples were obtained continuously for measurement of oxytocin (OT) levels. In both men and women, very high positive correlations were observed between the percentage change in levels from baseline through orgasm of: OT and SBP; OT and EMG intensity prior to and during orgasm; APG and EMG. The number of anal contractions and duration of orgasm were also highly correlated. Two patterns of orgasm were defined by the presence or absence of a quiescent period between orgasmic contractions. EMG and APG amplitudes correlated with the pattern of orgasm. Subjective orgasm intensity correlated significantly with increased levels of OT in multiorgasmic women only. The positive correlations between measures are consistent with a possible functional role for OT in human sexual response.

Student Progress to Graduation in New York City High Schools: A Metric Designed by New Visions for Public Schools. Part I: Core Components

ERIC Educational Resources Information Center

Fairchild, Susan; Gunton, Brad; Donohue, Beverly; Berry, Carolyn; Genn, Ruth; Knevals, Jessica

2011-01-01

Students who achieve critical academic benchmarks such as high attendance rates, continuous levels of credit accumulation, and high grades have a greater likelihood of success throughout high school and beyond. However, keeping students on track toward meeting graduation requirements and quickly identifying students who are at risk of falling off…

Observation of the continuous stern-gerlach effect on an electron bound in an atomic Ion

PubMed

Hermanspahn; Haffner; Kluge; Quint; Stahl; Verdu; Werth

2000-01-17

We report on the first observation of the continuous Stern-Gerlach effect on an electron bound in an atomic ion. The measurement was performed on a single hydrogenlike ion ( 12C5+) in a Penning trap. The measured g factor of the bound electron, g = 2.001 042(2), is in excellent agreement with the theoretical value, confirming the relativistic correction at a level of 0.1%. This proves the possibility of g-factor determinations on atomic ions to high precision by using the continuous Stern-Gerlach effect. The result demonstrates the feasibility of conducting experiments on single heavy highly charged ions to test quantum electrodynamics in the strong electric field of the nucleus.

Examining Spillovers between Long and Short Repeated Prisoner’s Dilemma Games Played in the Laboratory

PubMed Central

Arechar, Antonio A.; Kouchaki, Maryam; Rand, David G.

2018-01-01

We had participants play two sets of repeated Prisoner’s Dilemma (RPD) games, one with a large continuation probability and the other with a small continuation probability, as well as Dictator Games (DGs) before and after the RPDs. We find that, regardless of which is RPD set is played first, participants typically cooperate when the continuation probability is large and defect when the continuation probability is small. However, there is an asymmetry in behavior when transitioning from one continuation probability to the other. When switching from large to small, transient higher levels of cooperation are observed in the early games of the small continuation set. Conversely, when switching from small to large, cooperation is immediately high in the first game of the large continuation set. We also observe that response times increase when transitioning between sets of RPDs, except for altruistic participants transitioning into the set of RPDs with long continuation probabilities. These asymmetries suggest a bias in favor of cooperation. Finally, we examine the link between altruism and RPD play. We find that small continuation probability RPD play is correlated with giving in DGs played before and after the RPDs, whereas high continuation probability RPD play is not. PMID:29809199

Predicting the location of missing outer hair cells using the electrical signal recorded at the round window

PubMed Central

Chertoff, Mark E.; Earl, Brian R.; Diaz, Francisco J.; Sorensen, Janna L.; Thomas, Megan L. A.; Kamerer, Aryn M.; Peppi, Marcello

2014-01-01

The electrical signal recorded at the round window was used to estimate the location of missing outer hair cells. The cochlear response was recorded to a low frequency tone embedded in high-pass filtered noise conditions. Cochlear damage was created by either overexposure to frequency-specific tones or laser light. In animals with continuous damage along the partition, the amplitude of the cochlear response increased as the high-pass cutoff frequency increased, eventually reaching a plateau. The cochlear distance at the onset of the plateau correlated with the anatomical onset of outer hair cell loss. A mathematical model replicated the physiologic data but was limited to cases with continuous hair cell loss in the middle and basal turns. The neural contribution to the cochlear response was determined by recording the response before and after application of Ouabain. Application of Ouabain eliminated or reduced auditory neural activity from approximately two turns of the cochlea. The amplitude of the cochlear response was reduced for moderate signal levels with a limited effect at higher levels, indicating that the cochlear response was dominated by outer hair cell currents at high signal levels and neural potentials at low to moderate signal levels. PMID:25190395

Evaluation of High-Precision Sensors in Structural Monitoring

PubMed Central

Erol, Bihter

2010-01-01

One of the most intricate branches of metrology involves the monitoring of displacements and deformations of natural and anthropogenic structures under environmental forces, such as tidal or tectonic phenomena, or ground water level changes. Technological progress has changed the measurement process, and steadily increasing accuracy requirements have led to the continued development of new measuring instruments. The adoption of an appropriate measurement strategy, with proper instruments suited for the characteristics of the observed structure and its environmental conditions, is of high priority in the planning of deformation monitoring processes. This paper describes the use of precise digital inclination sensors in continuous monitoring of structural deformations. The topic is treated from two viewpoints: (i) evaluation of the performance of inclination sensors by comparing them to static and continuous GPS observations in deformation monitoring and (ii) providing a strategy for analyzing the structural deformations. The movements of two case study objects, a tall building and a geodetic monument in Istanbul, were separately monitored using dual-axes micro-radian precision inclination sensors (inclinometers) and GPS. The time series of continuous deformation observations were analyzed using the Least Squares Spectral Analysis Technique (LSSA). Overall, the inclinometers showed good performance for continuous monitoring of structural displacements, even at the sub-millimeter level. Static GPS observations remained insufficient for resolving the deformations to the sub-centimeter level due to the errors that affect GPS signals. With the accuracy advantage of inclination sensors, their use with GPS provides more detailed investigation of deformation phenomena. Using inclinometers and GPS is helpful to be able to identify the components of structural responses to the natural forces as static, quasi-static, or resonant. PMID:22163499

Sea Level History in 3D: Early results of an ultra-high resolution MCS survey across IODP Expedition 313 drillsites

NASA Astrophysics Data System (ADS)

Mountain, G. S.; Kucuk, H. M.; Nedimovic, M. R.; Austin, J. A., Jr.; Fulthorpe, C.; Newton, A.; Baldwin, K.; Johnson, C.; Stanley, J. N.; Bhatnagar, T.

2015-12-01

Although globally averaged sea level is rising at roughly 3 mm/yr (and is accelerating), rates of local sea-level change measured at coastlines may differ from this number by a factor of two or more; at some locations, sea level may even be falling. This is due to local processes that can match or even reverse the global trend, making it clear that reliable predictions of future impacts of sea-level rise require a firm understanding of processes at the local level. The history of local sea-level change and shoreline response is contained in the geologic record of shallow-water sediments. We report on a continuing study of sea-level history in sediments at the New Jersey continental margin, where compaction and glacial isostatic adjustment are currently adding 2 mm/yr to the globally averaged rise. We collected 570 sq km of ultra-high resolution 3D MCS data aboard the R/V Langseth in June-July 2015; innovative recording and preliminary results are described by Nedimovic et al. in this same session. The goal was to provide regional context to coring and logging at IODP Exp 313 sites 27-29 that were drilled 750 m into the New Jersey shelf in 2009. These sites recovered a nearly continuous record of post-Eocene sediments from non-marine soils, estuaries, shoreface, delta front, pro-delta and open marine settings. Existing seismic data are good but are 2D high-resolution profiles at line spacings too wide to enable mapping of key nearshore features. The Langseth 3D survey used shallow towing of a tuned air gun array to preserve high frequencies, and twenty-four 50-m PCables each 12.5 apart provided 6.25 x 3.125 m common-midpoint bins along seventy-seven 50-km sail lines. With this especially dense spatial resolution of a pre-stack time migrated volume we expect to map rivers, incised valleys, barrier islands, inlets and bays, pro-delta clinoforms, tidal deltas, sequence boundaries, debris flow aprons, and more. Seismic attributes linked to sedimentary facies and geochronology at Exp 313 drill sites will be extended throughout the volume to map the local response to global sea-level change. These analyses will provide an unrivaled opportunity to gauge the local expression of sea-level change for much of the last 40 Ma and lead to informed predictions regarding impacts of a global rise of sea level expected to continue well into the future.

Noise levels in fitness classes are still too high: evidence from 1997-1998 and 2009-2011.

PubMed

Beach, Elizabeth Francis; Nie, Valerie

2014-01-01

Fitness instructors routinely use high music volumes that may be harmful to hearing. This study assessed noise levels during 35 low-intensity and 65 high-intensity fitness classes in 1997-1998 and 2009-2011. Questionnaires examined instructors' and clients' preferred music volumes and whether they found loud music "stressful" or "motivating." Noise levels in 1997-1998 and 2009-2011 were similar, frequently exceeding 90 dB(A). Although noise levels in low-intensity classes dropped from 88.9 to 85.6 dB(A), they remained high for high-intensity classes, averaging 93.1 dB(A). In 2009-2011, instructors preferred significantly higher volumes than clients for high-intensity classes. In both time periods, about 85% of instructors found loud music motivating, whereas about one fifth of clients found it stressful. The results suggest that noise exposure from fitness classes, particularly high-intensity classes, continues to pose a potential risk to hearing.

Experimental investigation of control/display augmentation effects in a compensatory tracking task

NASA Technical Reports Server (NTRS)

Garg, Sanjay; Schmidt, David K.

1988-01-01

The effects of control/display augmentation on human performance and workload have been investigated for closed-loop, continuous-tracking tasks by a real-time, man-in-the-loop simulation study. The experimental results obtained indicate that only limited improvement in actual tracking performance is obtainable through display augmentation alone; with a very high level of display augmentation, tracking error will actually deteriorate. Tracking performance improves when status information is furnished for reasonable levels of display quickening; again, very high quickening levels lead to tracking error deterioration due to the incompatibility between the status information and the quickened signal.

Continuous traumatic stress as a mental and physical health challenge: Case studies from South Africa.

PubMed

Kaminer, Debra; Eagle, Gillian; Crawford-Browne, Sarah

2018-07-01

This article discusses the condition of continuous traumatic stress as common on the African continent and in other international settings characterised by very high levels of ongoing violence and threat of community, political or war-related origin. Through consideration of three case studies from South Africa, contexts of continuous traumatic stress are described, and the mental health and physical health effects of living in such contexts are elaborated. Cautions are raised about attempting to transpose existing posttraumatic stress models onto individuals exposed to situations of continuous traumatic stress, and guidelines for optimal interventions with such cases are proposed.

Mercury Phase II Study - Mercury Behavior across the High-Level Waste Evaporator System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bannochie, C. J.; Crawford, C. L.; Jackson, D. G.

2016-06-17

The Mercury Program team’s effort continues to develop more fundamental information concerning mercury behavior across the liquid waste facilities and unit operations. Previously, the team examined the mercury chemistry across salt processing, including the Actinide Removal Process/Modular Caustic Side Solvent Extraction Unit (ARP/MCU), and the Defense Waste Processing Facility (DWPF) flowsheets. This report documents the data and understanding of mercury across the high level waste 2H and 3H evaporator systems.

Fiber fuse behavior in kW-level continuous-wave double-clad field laser

NASA Astrophysics Data System (ADS)

Jun-Yi, Sun; Qi-Rong, Xiao; Dan, Li; Xue-Jiao, Wang; Hai-Tao, Zhang; Ma-Li, Gong; Ping, Yan

2016-01-01

In this study, original experimental data for fiber fuse in kW-level continuous-wave (CW) high power double-clad fiber (DCF) laser are reported. The propagating velocity of the fuse is 9.68 m/s in a 3.1-kW Yb-doped DCF laser. Three other cases in Yb-doped DCF are also observed. We think that the ignition of fiber fuse is caused by thermal mechanism, and the formation of bullet-shaped tracks is attributed to the optical discharge and temperature gradient. The inducements of initial fuse and formation of bullet-shaped voids are analyzed. This investigation of fiber fuse helps better understand the fiber fuse behavior, in order to avoid the catastrophic destruction caused by fiber fuse in high power fiber laser. Project supported by the Key Laboratory of Science and Technology on High Energy Laser and China Academy of Engineering Physics (Grant No. 2014HEL02) and the National Natural Science Foundation of China (Grant No. 61307057).

Paclitaxel synergizes with exposure time adjusted CD22-targeting immunotoxins against B-cell malignancies.

PubMed

Müller, Fabian; Stookey, Stephanie; Cunningham, Tyler; Pastan, Ira

2017-05-09

CD22-targeted recombinant immunotoxins (rIT) are active in hairy cell leukemia or acute lymphoblastic leukemia (ALL), but not in mantle cell lymphoma (MCL) patients. The goal was to enhance rIT efficacy in vivo and to define a strong combination treatment. Activity of Moxetumomab pasudotox (Moxe) and LR combined with paclitaxel was tested against MCL cell lines in vitro and as bolus doses or continuous infusion in xenograft models. In the KOPN-8 ALL xenograft, Moxe or paclitaxel alone was active, but all mice died from leukemia; when combined, 60% of the mice achieved a sustained complete remission. Against MCL cells in vitro, LR was more active than Moxe and the cells had to be exposed to rIT for more than 24 hours for them to die. To maintain high blood levels in vivo, LR was administered continuously by 7-day pumps achieving a well-tolerated steady plasma concentration of 45 ng/ml. In JeKo-1 xenografts, continuously administered LR was 14-fold more active than bolus doses and the combination with paclitaxel additionally improved responses by 135-fold. Maintaining high rIT-plasma levels greatly improves responses in the JeKo-1 model and paclitaxel substantially enhances bolus and continuously infused rIT, supporting a clinical evaluation against B-cell malignancies.

Scaling characteristics of mountainous river flow fluctuations determined using a shallow-water acoustic tomography system

NASA Astrophysics Data System (ADS)

Al Sawaf, Mohamad Basel; Kawanisi, Kiyosi; Kagami, Junya; Bahreinimotlagh, Masoud; Danial, Mochammad Meddy

2017-10-01

The aim of this study is to investigate the scaling exponent properties of mountainous river flow fluctuations by detrended fluctuation analysis (DFA). Streamflow data were collected continuously using Fluvial Acoustic Tomography System (FATS), which is a novel system for measuring continuous streamflow at high-frequency scales. The results revealed that river discharge fluctuations have two scaling regimes and scaling break. In contrast to the Ranting Curve method (RC), the small-scale exponent detected by the FATS is estimated to be 1.02 ± 0.42% less than that estimated by RC. More importantly, the crossover times evaluated from the FATS delayed approximately by 42 ± 21 hr ≈2-3 days than their counterparts estimated by RC. The power spectral density analysis assists our findings. We found that scaling characteristics information evaluated for a river using flux data obtained by RC approach might not be accurately detected, because this classical method assumes that flow in river is steady and depends on constructing a relationship between discharge and water level, while the discharge obtained by the FATS decomposes velocity and depth into two ratings according to the continuity equation. Generally, this work highlights the performance of FATS as a powerful and effective approach for continuous streamflow measurements at high-frequency levels.

Variability, constraints, and creativity. Shedding light on Claude Monet.

PubMed

Stokes, P D

2001-04-01

Recent experimental research suggests 2 things. The first is that along with learning how to do something, people also learn how variably or differently to continue doing it. The second is that high variability is maintained by constraining, precluding a currently successful, often repetitive solution to a problem. In this view, Claude Monet's habitually high level of variability in painting was acquired during his childhood and early apprenticeship and was maintained throughout his adult career by a continuous series of task constraints imposed by the artist on his own work. For Monet, variability was rewarded and rewarding.

Integrated injection-locked semiconductor diode laser

DOEpatents

Hadley, G.R.; Hohimer, J.P.; Owyoung, A.

1991-02-19

A continuous wave integrated injection-locked high-power diode laser array is provided with an on-chip independently-controlled master laser. The integrated injection locked high-power diode laser array is capable of continuous wave lasing in a single near-diffraction limited output beam at single-facet power levels up to 125 mW (250 mW total). Electronic steering of the array emission over an angle of 0.5 degrees is obtained by varying current to the master laser. The master laser injects a laser beam into the slave array by reflection of a rear facet. 18 figures.

Continuous 1.3-million-year record of East African hydroclimate, and implications for patterns of evolution and biodiversity

NASA Astrophysics Data System (ADS)

Lyons, Robert P.; Scholz, Christopher A.; Cohen, Andrew S.; King, John W.; Brown, Erik T.; Ivory, Sarah J.; Johnson, Thomas C.; Deino, Alan L.; Reinthal, Peter N.; McGlue, Michael M.; Blome, Margaret W.

2015-12-01

The transport of moisture in the tropics is a critical process for the global energy budget and on geologic timescales, has markedly influenced continental landscapes, migratory pathways, and biological evolution. Here we present a continuous, first-of-its-kind 1.3-My record of continental hydroclimate and lake-level variability derived from drill core data from Lake Malawi, East Africa (9-15° S). Over the Quaternary, we observe dramatic shifts in effective moisture, resulting in large-scale changes in one of the world's largest lakes and most diverse freshwater ecosystems. Results show evidence for 24 lake level drops of more than 200 m during the Late Quaternary, including 15 lowstands when water levels were more than 400 m lower than modern. A dramatic shift is observed at the Mid-Pleistocene Transition (MPT), consistent with far-field climate forcing, which separates vastly different hydroclimate regimes before and after ∼800,000 years ago. Before 800 ka, lake levels were lower, indicating a climate drier than today, and water levels changed frequently. Following the MPT high-amplitude lake level variations dominate the record. From 800 to 100 ka, a deep, often overfilled lake occupied the basin, indicating a wetter climate, but these highstands were interrupted by prolonged intervals of extreme drought. Periods of high lake level are observed during times of high eccentricity. The extreme hydroclimate variability exerted a profound influence on the Lake Malawi endemic cichlid fish species flock; the geographically extensive habitat reconfiguration provided novel ecological opportunities, enabling new populations to differentiate rapidly to distinct species.

Continuous 1.3-million-year record of East African hydroclimate, and implications for patterns of evolution and biodiversity

PubMed Central

Lyons, Robert P.; Scholz, Christopher A.; Cohen, Andrew S.; King, John W.; Brown, Erik T.; Ivory, Sarah J.; Johnson, Thomas C.; Deino, Alan L.; Reinthal, Peter N.; McGlue, Michael M.; Blome, Margaret W.

2015-01-01

The transport of moisture in the tropics is a critical process for the global energy budget and on geologic timescales, has markedly influenced continental landscapes, migratory pathways, and biological evolution. Here we present a continuous, first-of-its-kind 1.3-My record of continental hydroclimate and lake-level variability derived from drill core data from Lake Malawi, East Africa (9–15° S). Over the Quaternary, we observe dramatic shifts in effective moisture, resulting in large-scale changes in one of the world’s largest lakes and most diverse freshwater ecosystems. Results show evidence for 24 lake level drops of more than 200 m during the Late Quaternary, including 15 lowstands when water levels were more than 400 m lower than modern. A dramatic shift is observed at the Mid-Pleistocene Transition (MPT), consistent with far-field climate forcing, which separates vastly different hydroclimate regimes before and after ∼800,000 years ago. Before 800 ka, lake levels were lower, indicating a climate drier than today, and water levels changed frequently. Following the MPT high-amplitude lake level variations dominate the record. From 800 to 100 ka, a deep, often overfilled lake occupied the basin, indicating a wetter climate, but these highstands were interrupted by prolonged intervals of extreme drought. Periods of high lake level are observed during times of high eccentricity. The extreme hydroclimate variability exerted a profound influence on the Lake Malawi endemic cichlid fish species flock; the geographically extensive habitat reconfiguration provided novel ecological opportunities, enabling new populations to differentiate rapidly to distinct species. PMID:26644580

Continuous 1.3-million-year record of East African hydroclimate, and implications for patterns of evolution and biodiversity.

PubMed

Lyons, Robert P; Scholz, Christopher A; Cohen, Andrew S; King, John W; Brown, Erik T; Ivory, Sarah J; Johnson, Thomas C; Deino, Alan L; Reinthal, Peter N; McGlue, Michael M; Blome, Margaret W

2015-12-22

The transport of moisture in the tropics is a critical process for the global energy budget and on geologic timescales, has markedly influenced continental landscapes, migratory pathways, and biological evolution. Here we present a continuous, first-of-its-kind 1.3-My record of continental hydroclimate and lake-level variability derived from drill core data from Lake Malawi, East Africa (9-15° S). Over the Quaternary, we observe dramatic shifts in effective moisture, resulting in large-scale changes in one of the world's largest lakes and most diverse freshwater ecosystems. Results show evidence for 24 lake level drops of more than 200 m during the Late Quaternary, including 15 lowstands when water levels were more than 400 m lower than modern. A dramatic shift is observed at the Mid-Pleistocene Transition (MPT), consistent with far-field climate forcing, which separates vastly different hydroclimate regimes before and after ∼800,000 years ago. Before 800 ka, lake levels were lower, indicating a climate drier than today, and water levels changed frequently. Following the MPT high-amplitude lake level variations dominate the record. From 800 to 100 ka, a deep, often overfilled lake occupied the basin, indicating a wetter climate, but these highstands were interrupted by prolonged intervals of extreme drought. Periods of high lake level are observed during times of high eccentricity. The extreme hydroclimate variability exerted a profound influence on the Lake Malawi endemic cichlid fish species flock; the geographically extensive habitat reconfiguration provided novel ecological opportunities, enabling new populations to differentiate rapidly to distinct species.

Multidecadal shoreline changes of atoll islands in the Marshall Islands

NASA Astrophysics Data System (ADS)

Ford, M.

2012-12-01

Atoll islands are considered highly vulnerable to the impacts of continued sea level rise. One of the most commonly predicted outcomes of continued sea level rise is widespread and chronic shoreline erosion. Despite the widespread implications of predicted erosion, the decadal scale changes of atoll island shorelines are poorly resolved. The Marshall Islands is one of only four countries where the majority of inhabited land is comprised of reef and atoll islands. Consisting of 29 atolls and 5 mid-ocean reef islands, the Marshall Islands are considered highly vulnerable to the impacts of sea level rise. A detailed analysis of shoreline change on over 300 islands on 10 atolls was undertaken using historic aerial photos (1945-1978) and modern high resolution satellite imagery (2004-2012). Results highlight the complex and dynamic nature of atoll islands, with significant shifts in shoreline position observed over the period of analysis. Results suggest shoreline accretion is the dominant mode of change on the islands studied, often associated with a net increase in vegetated island area. However, considerable inter- and intra-atoll variability exists with regards to shoreline stability. Findings are discussed with respect to island morphodynamics and potential hazard mitigation and planning responses within atoll settings.

High-precision GPS autonomous platforms for sea ice dynamics and physical oceanography

NASA Astrophysics Data System (ADS)

Elosegui, P.; Wilkinson, J.; Olsson, M.; Rodwell, S.; James, A.; Hagan, B.; Hwang, B.; Forsberg, R.; Gerdes, R.; Johannessen, J.; Wadhams, P.; Nettles, M.; Padman, L.

2012-12-01

Project "Arctic Ocean sea ice and ocean circulation using satellite methods" (SATICE), is the first high-rate, high-precision, continuous GPS positioning experiment on sea ice in the Arctic Ocean. The SATICE systems collect continuous, dual-frequency carrier-phase GPS data while drifting on sea ice. Additional geophysical measurements also collected include ocean water pressure, ocean surface salinity, atmospheric pressure, snow-depth, air-ice-ocean temperature profiles, photographic imagery, and others, enabling sea ice drift, freeboard, weather, ice mass balance, and sea-level height determination. Relatively large volumes of data from each buoy are streamed over a satellite link to a central computer on the Internet in near real time, where they are processed to estimate the time-varying buoy positions. SATICE system obtains continuous GPS data at sub-minute intervals with a positioning precision of a few centimetres in all three dimensions. Although monitoring of sea ice motions goes back to the early days of satellite observations, these autonomous platforms bring out a level of spatio-temporal detail that has never been seen before, especially in the vertical axis. These high-resolution data allows us to address new polar science questions and challenge our present understanding of both sea ice dynamics and Arctic oceanography. We will describe the technology behind this new autonomous platform, which could also be adapted to other applications that require high resolution positioning information with sustained operations and observations in the polar marine environment, and present results pertaining to sea ice dynamics and physical oceanography.

THE EFFECT OF GESTATIONAL MERCURY VAPOR EXPOSURE ON RAT BRAIN A-SYNUCLEIN EXPRESSION.

EPA Science Inventory

Alpha-synuclein is a highly conserved protein that localizes to pre-synaptic terminals and is thought to play a role in neuronal plasticity. It is upregulated developmentally and continues to be expressed at high levels in the adult brain. Its presence in a number of neuronal (A...

Noise, air pollutants and traffic: continuous measurement and correlation at a high-traffic location in New York City.

PubMed

Ross, Zev; Kheirbek, Iyad; Clougherty, Jane E; Ito, Kazuhiko; Matte, Thomas; Markowitz, Steven; Eisl, Holger

2011-11-01

Epidemiological studies have linked both noise and air pollution to common adverse health outcomes such as increased blood pressure and myocardial infarction. In urban settings, noise and air pollution share important sources, notably traffic, and several recent studies have shown spatial correlations between noise and air pollution. The temporal association between these exposures, however, has yet to be thoroughly investigated despite the importance of time series studies in air pollution epidemiology and the potential that correlations between these exposures could at least partly confound statistical associations identified in these studies. An aethelometer, for continuous elemental carbon measurement, was co-located with a continuous noise monitor near a major urban highway in New York City for six days in August 2009. Hourly elemental carbon measurements and hourly data on overall noise levels and low, medium and high frequency noise levels were collected. Hourly average concentrations of fine particles and nitrogen oxides, wind speed and direction and car, truck and bus traffic were obtained from nearby regulatory monitors. Overall temporal patterns, as well as day-night and weekday-weekend patterns, were characterized and compared for all variables. Noise levels were correlated with car, truck, and bus traffic and with air pollutants. We observed strong day-night and weekday-weekend variation in noise and air pollutants and correlations between pollutants varied by noise frequency. Medium and high frequency noise were generally more strongly correlated with traffic and traffic-related pollutants than low frequency noise and the correlation with medium and high frequency noise was generally stronger at night. Correlations with nighttime high frequency noise were particularly high for car traffic (Spearman rho=0.84), nitric oxide (0.73) and nitrogen dioxide (0.83). Wind speed and direction mediated relationships between pollutants and noise. Noise levels are temporally correlated with traffic and combustion pollutants and correlations are modified by the time of day, noise frequency and wind. Our results underscore the potential importance of assessing temporal variation in co-exposures to noise and air pollution in studies of the health effects of these urban pollutants. Copyright © 2011 Elsevier Inc. All rights reserved.

Functions of autobiographical memory in Taiwanese and American emerging adults.

PubMed

Liao, Hsiao-Wen; Bluck, Susan; Alea, Nicole; Cheng, Ching-Ling

2016-01-01

The study addresses cultural and person-level factors contributing to emerging adult's use of memory to serve adaptive functions. The focus is on three functions: self-continuity, social-bonding and directing-behaviour. Taiwanese (N = 85, 52 women) and American (N = 95, 51 women) emerging adults completed the Thinking about Life Experiences scale, and measures of trait personality, self-concept clarity and future time perspective. Findings show that individuals from both cultures use memory to serve these three functions, but Taiwanese individuals use memory more frequently than Americans to maintain self-continuity. Culture also interacted with person-level factors: in Taiwan, but not America, memory is more frequently used to create self-continuity in individuals high in conscientiousness. Across cultures, having lower self-concept clarity was related to greater use of memory to create self-continuity. Findings are discussed in terms of how memory serves functions in context and specific aspects of the Taiwanese and American cultural context that may predict the functional use of memory in emerging adulthood.

Hydrogen-Detection Apparatus

NASA Technical Reports Server (NTRS)

Ross, H. Richard; Bourgeois, Chris M.

1995-01-01

Apparatus continuously monitors concentration of hydrogen, at level ranging from few parts per million to several percent, in mixture of gases. Simple and fast, providing high sensitivity and linear response. Used to alert technicians to potentially explosive concentrations of residual hydrogen.

10 CFR 60.122 - Siting criteria.

Code of Federal Regulations, 2010 CFR

2010-01-01

... with low horizontal and vertical permeability; (ii) Downward or dominantly horizontal hydraulic... permeability and low hydraulic gradient between the host rock and the surrounding hydrogeologic units. (3... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

Is income or employment a stronger predictor of smoking than education in economically less developed countries? A cross-sectional study in Hungary.

PubMed

Leinsalu, Mall; Kaposvári, Csilla; Kunst, Anton E

2011-02-13

In developed European countries in the last phase of the smoking epidemic, education is a stronger predictor of smoking than income or employment. We examine whether this also applies in economically less developed countries. Data from 7218 respondents in the 25-64 age group came from two National Health Interview Surveys conducted in 2000 and 2003 in Hungary. Independent effects of educational level, income and employment status were studied in relation to smoking prevalence, initiation and continuation for all age groups combined and separately for 25-34, 35-49 and 50-64 years old. Absolute levels were evaluated by using age-standardized prevalence rates. Relative differences were assessed by means of logistic regression. Education and income, but not employment, were associated with equally large differences in smoking prevalence in Hungary in the 25-64 age group. Among men, smoking initiation was related to low educational level, whereas smoking continuation was related to low income. Among women, low education and low income were associated with both high initiation and high continuation rates. Considerable differences were found between the age groups. Inverse social gradients were generally strongest in the youngest age groups. However, smoking continuation among men had the strongest association with low income for the middle-aged group. Patterns of inequalities in smoking in Hungary can be best understood in relation to two processes: the smoking epidemic, and the additional effects of poverty. Equity orientated tobacco control measures should target the low educated to prevent their smoking initiation, and the poor to improve their cessation rates.

Single-cell imaging tools for brain energy metabolism: a review

PubMed Central

San Martín, Alejandro; Sotelo-Hitschfeld, Tamara; Lerchundi, Rodrigo; Fernández-Moncada, Ignacio; Ceballo, Sebastian; Valdebenito, Rocío; Baeza-Lehnert, Felipe; Alegría, Karin; Contreras-Baeza, Yasna; Garrido-Gerter, Pamela; Romero-Gómez, Ignacio; Barros, L. Felipe

2014-01-01

Abstract. Neurophotonics comes to light at a time in which advances in microscopy and improved calcium reporters are paving the way toward high-resolution functional mapping of the brain. This review relates to a parallel revolution in metabolism. We argue that metabolism needs to be approached both in vitro and in vivo, and that it does not just exist as a low-level platform but is also a relevant player in information processing. In recent years, genetically encoded fluorescent nanosensors have been introduced to measure glucose, glutamate, ATP, NADH, lactate, and pyruvate in mammalian cells. Reporting relative metabolite levels, absolute concentrations, and metabolic fluxes, these sensors are instrumental for the discovery of new molecular mechanisms. Sensors continue to be developed, which together with a continued improvement in protein expression strategies and new imaging technologies, herald an exciting era of high-resolution characterization of metabolism in the brain and other organs. PMID:26157964

Health Care Finance Executive Personalities Revisited: A 10-Year Follow-up Study.

PubMed

Lieneck, Cristian; Nowicki, Michael

2015-01-01

A dynamic health care industry continues to call upon health care leaders to possess not one but multiple competencies. Inherent personality characteristics of leaders often play a major role in personal as well as organizational success to include those in health care finance positions of responsibility. A replication study was conducted to determine the Myers-Briggs personality-type differences between practicing health care finance professionals in 2014, as compared with a previous 2003 study. Results indicate a significant shift between both independent samples of health care finance professionals over the 10-year period from original high levels of introversion to that of extraversion, as well as higher sensing personality preferences, as compared with the original sample's high level of intuition preferences. Further investigation into the evolving role of the health care finance manager is suggested, while continued alignment of inherent, personal characteristics is suggested to meet ongoing changes in the industry.

[Financial protection in health: updates for Mexico to 2014].

PubMed

Knaul, Felicia Marie; Arreola-Ornelas, Héctor; Méndez-Carniado, Oscar

2016-06-01

Objetive: Document financial protection in health in Mexico up to 2014. We up date the measures of impoverishing and catastrophic health expenditure to 2014, to analyse shifts since the implementation of the System for Social Protection in Health and the Seguro Popular using time series data from the Household Income and Expenditure Survey. Between 2004 and 2014 there has been a continued improvement in levels of financial protection. Excessive expenditure reached its lowest point: -2.0% in 2012 and 2.1% in 2014. Impoverishing expenditure dropped to 1.3% in 2004, compared to 0.5% in 2014, and catastrophic expenditures from 2.7% to 2.1%. The time series of data on financial protection show a clear pattern of improvement between 2000 and 2014 and level off and low levels in 2012 and 2014. Still, levels continue to be relatively high for households in the poorest quintile, in rural areas and with an elderly person.

Drinking Level Versus Drinking Pattern and Cigarette Smoking Among Older Adults.

PubMed

Holahan, Charles J; Brennan, Penny L; Schutte, Kathleen K; Holahan, Carole K; Hixon, J Gregory; Moos, Rudolf H

2018-04-01

There is a lack of research on the role of alcohol consumption in cigarette smoking among older adults, and the few studies on alcohol use and smoking with older adults have failed to distinguish between average level and pattern of drinking as predictors of smoking. The main purpose of this study was to examine the independent contributions of average level versus pattern of drinking as predictors of cigarette smoking among older adults. A subsidiary purpose was to examine the link between continued smoking and mortality among older smokers. We investigated average level and pattern of drinking as predictors of current smoking among 1,151 older adults at baseline and of continued smoking and mortality among the subset of 276 baseline smokers tracked across 20 years. We used multiple linear and logistic regression analyses and, to test mediation, bias-corrected bootstrap confidence intervals. A high level of average drinking and a pattern of episodic heavy drinking were concurrently associated with smoking at baseline. However, only episodic heavy drinking was prospectively linked to continued smoking among baseline smokers. Continued smoking among baseline smokers increased the odds of 20-year mortality and provided an indirect pathway through which heavy episodic drinking related to mortality. Smokers who misuse alcohol are a challenging population for smoking cessation efforts. Older adults who concurrently misuse alcohol and smoke cigarettes provide a unique target for public health interventions. Copyright © 2018 by the Research Society on Alcoholism.

Transcriptome Analysis Reveals Signature of Adaptation to Landscape Fragmentation

PubMed Central

Ikonen, Suvi; Auvinen, Petri; Paulin, Lars; Koskinen, Patrik; Holm, Liisa; Taipale, Minna; Duplouy, Anne; Ruokolainen, Annukka; Saarnio, Suvi; Sirén, Jukka; Kohonen, Jukka; Corander, Jukka; Frilander, Mikko J.; Ahola, Virpi; Hanski, Ilkka

2014-01-01

We characterize allelic and gene expression variation between populations of the Glanville fritillary butterfly (Melitaea cinxia) from two fragmented and two continuous landscapes in northern Europe. The populations exhibit significant differences in their life history traits, e.g. butterflies from fragmented landscapes have higher flight metabolic rate and dispersal rate in the field, and higher larval growth rate, than butterflies from continuous landscapes. In fragmented landscapes, local populations are small and have a high risk of local extinction, and hence the long-term persistence at the landscape level is based on frequent re-colonization of vacant habitat patches, which is predicted to select for increased dispersal rate. Using RNA-seq data and a common garden experiment, we found that a large number of genes (1,841) were differentially expressed between the landscape types. Hexamerin genes, the expression of which has previously been shown to have high heritability and which correlate strongly with larval development time in the Glanville fritillary, had higher expression in fragmented than continuous landscapes. Genes that were more highly expressed in butterflies from newly-established than old local populations within a fragmented landscape were also more highly expressed, at the landscape level, in fragmented than continuous landscapes. This result suggests that recurrent extinctions and re-colonizations in fragmented landscapes select a for specific expression profile. Genes that were significantly up-regulated following an experimental flight treatment had higher basal expression in fragmented landscapes, indicating that these butterflies are genetically primed for frequent flight. Active flight causes oxidative stress, but butterflies from fragmented landscapes were more tolerant of hypoxia. We conclude that differences in gene expression between the landscape types reflect genomic adaptations to landscape fragmentation. PMID:24988207

Transcriptome analysis reveals signature of adaptation to landscape fragmentation.

PubMed

Somervuo, Panu; Kvist, Jouni; Ikonen, Suvi; Auvinen, Petri; Paulin, Lars; Koskinen, Patrik; Holm, Liisa; Taipale, Minna; Duplouy, Anne; Ruokolainen, Annukka; Saarnio, Suvi; Sirén, Jukka; Kohonen, Jukka; Corander, Jukka; Frilander, Mikko J; Ahola, Virpi; Hanski, Ilkka

2014-01-01

We characterize allelic and gene expression variation between populations of the Glanville fritillary butterfly (Melitaea cinxia) from two fragmented and two continuous landscapes in northern Europe. The populations exhibit significant differences in their life history traits, e.g. butterflies from fragmented landscapes have higher flight metabolic rate and dispersal rate in the field, and higher larval growth rate, than butterflies from continuous landscapes. In fragmented landscapes, local populations are small and have a high risk of local extinction, and hence the long-term persistence at the landscape level is based on frequent re-colonization of vacant habitat patches, which is predicted to select for increased dispersal rate. Using RNA-seq data and a common garden experiment, we found that a large number of genes (1,841) were differentially expressed between the landscape types. Hexamerin genes, the expression of which has previously been shown to have high heritability and which correlate strongly with larval development time in the Glanville fritillary, had higher expression in fragmented than continuous landscapes. Genes that were more highly expressed in butterflies from newly-established than old local populations within a fragmented landscape were also more highly expressed, at the landscape level, in fragmented than continuous landscapes. This result suggests that recurrent extinctions and re-colonizations in fragmented landscapes select a for specific expression profile. Genes that were significantly up-regulated following an experimental flight treatment had higher basal expression in fragmented landscapes, indicating that these butterflies are genetically primed for frequent flight. Active flight causes oxidative stress, but butterflies from fragmented landscapes were more tolerant of hypoxia. We conclude that differences in gene expression between the landscape types reflect genomic adaptations to landscape fragmentation.

The thermal triple-axis-spectrometer EIGER at the continuous spallation source SINQ

NASA Astrophysics Data System (ADS)

Stuhr, U.; Roessli, B.; Gvasaliya, S.; Rønnow, H. M.; Filges, U.; Graf, D.; Bollhalder, A.; Hohl, D.; Bürge, R.; Schild, M.; Holitzner, L.; Kaegi, C.,; Keller, P.; Mühlebach, T.

2017-05-01

EIGER is the new thermal triple-axis-spectrometer at the continuous spallation SINQ at PSI. The shielding of the monochromator consists only of non- or low magnetizable materials, which allows the use of strong magnetic fields with the instrument. This shielding reduces the high energy neutron contamination to a comparable level of thermal spectrometers at reactor sources. The instrument design, the performance and first results of the spectrometer are presented.

HigherEdUtah2020. 2014 Report

ERIC Educational Resources Information Center

Utah System of Higher Education, 2014

2014-01-01

Utah has set the goal of having 66% of its 25-35 age population with a post-secondary degree or certificate by 2020. To achieve this goal, Utah must increase the number of degrees and certificates awarded annually, to a level 25% above the 2010-11 base year level. This requires a continuing focused effort in creating a highly-educated workforce. A…

The strategic skills of business continuity managers: putting business continuity management into corporate long-term planning.

PubMed

Wong, Wei Ning Zechariah

2009-11-01

Despite its rapid development in the last two decades, business continuity management (BCM) as a discipline and a profession is still regarded by many as an operational entity of management. Two main issues are discussed in this paper: the role of BCM in strategic management and the strategic skills of business continuity managers. These issues are crucial as they represent the role of BCM in high-level corporate management. The paper discusses the importance of BCM in the long-term planning of organisational success and the preservation of future competitiveness. Finally, salient points that underpin the importance of its role in sustaining organisational performance are addressed.

Lifelong learning as an instrument for human capital development in Benin

NASA Astrophysics Data System (ADS)

Biao, Idowu

2015-10-01

A review of the Benin education system shows that it is still heavily school-based. Yet, a high level of wastage is currently being recorded at school level (about 50% success rate at primary level, about 40% success rate at high school level and about 1% enrolment rate of qualified candidates and success rate at tertiary level), leading to the unintentional creation of a large population of unskilled and unproductive youths and adults. Integrated education systems which hold great potential and opportunities for both initial and continuing education remain hardly explored and virtually untapped. Yet, the challenges of the 21st century are such that only the unveiling and continuous cultivation of multi-faceted human capital can help individual citizens lead both a productive and fulfilled life. Formal education alone or non-formal education alone, irrespective of how well each is delivered, is no longer sufficient in facing up to the multifarious challenges of the 21st century. If education is to serve Benin beneficially in this century, the current national system of education must be reoriented to free up citizens' human capital through the implementation of an integrated educational system. This article proposes a new national education system which is rooted in the concept of lifelong learning and combines formal and non-formal systems of education for Benin.

Thyroid nodularity and chromosome aberrations among women in areas of high background radiation in China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Z.Y.; Boice, J.D. Jr.; Wei, L.X.

1990-03-21

Thyroid nodularity following continuous low-dose radiation exposure in China was determined in 1,001 women aged 50-65 years who resided in areas of high background radiation (330 mR/yr) their entire lives, and in 1,005 comparison subjects exposed to normal levels of radiation (114 mR/yr). Cumulative doses to the thyroid were estimated to be of the order of 14 cGy and 5 cGy, respectively. Personal interviews and physical examinations were conducted, and measurements were made of serum thyroid hormone levels, urinary iodine concentrations, and chromosome aberrations in circulating lymphocytes. For all nodular disease, the prevalences in the high background and control areasmore » were 9.5% and 9.3%, respectively. For single nodules, the prevalences were 7.4% in the high background area and 6.6% in the control area (prevalence ratio = 1.13; 95% confidence interval = 0.82-1.55). There were no differences found in serum levels of thyroid hormones. Women in the high background region, however, had significantly lower concentrations of urinary iodine and significantly higher frequencies of stable and unstable chromosome aberrations. Increased intake of allium vegetables such as garlic and onions was associated with a decreased risk of nodular disease, which seems consistent with experimental studies suggesting that allium compounds can inhibit tumor growth and proliferation. The prevalence of mild diffuse goiter was higher in the high background radiation region, perhaps related to a low dietary intake of iodine. These data suggest that continuous exposure to low-level radiation throughout life is unlikely to appreciably increase the risk of thyroid cancer. However, such exposure may cause chromosomal damage.« less

Diderot: a Domain-Specific Language for Portable Parallel Scientific Visualization and Image Analysis.

PubMed

Kindlmann, Gordon; Chiw, Charisee; Seltzer, Nicholas; Samuels, Lamont; Reppy, John

2016-01-01

Many algorithms for scientific visualization and image analysis are rooted in the world of continuous scalar, vector, and tensor fields, but are programmed in low-level languages and libraries that obscure their mathematical foundations. Diderot is a parallel domain-specific language that is designed to bridge this semantic gap by providing the programmer with a high-level, mathematical programming notation that allows direct expression of mathematical concepts in code. Furthermore, Diderot provides parallel performance that takes advantage of modern multicore processors and GPUs. The high-level notation allows a concise and natural expression of the algorithms and the parallelism allows efficient execution on real-world datasets.

Why So Few? Women in Science, Technology, Engineering, and Mathematics

ERIC Educational Resources Information Center

Hill, Catherine; Corbett, Christianne; St. Rose, Andresse

2010-01-01

The number of women in science and engineering is growing, yet men continue to outnumber women, especially at the upper levels of these professions. In elementary, middle, and high school, girls and boys take math and science courses in roughly equal numbers, and about as many girls as boys leave high school prepared to pursue science and…

When Volunteering Is Mandatory: A Call for Research about Service Learning

ERIC Educational Resources Information Center

Cloyd, Melissa

2017-01-01

Stakeholders have long been concerned about high school drop-out rates and associated achievement gaps between groups, specifically racial, of high school students. While significant improvements have been made to these drop-out rates at the national level, the largest group of drop-out students continues to be those of Hispanic heritage. Research…

Characterization of adsorption on the stationary phase using high-performance immunoaffinity chromatography.

PubMed

Nielsen, R G; Wilson, G S

1987-12-25

Low-level adsorption on the stationary phase has been studied using immunochemical reagents. An immunoaffinity column has been evaluated using affinity-purified radioisotope-labeled monoclonal antibodies. Recovery experiments including continuous immunosorbent monitoring have been performed. Proper characterization of an immunoaffinity separation can result in the recovery of immunologically active material in high yield.

On application of kernel PCA for generating stimulus features for fMRI during continuous music listening.

PubMed

Tsatsishvili, Valeri; Burunat, Iballa; Cong, Fengyu; Toiviainen, Petri; Alluri, Vinoo; Ristaniemi, Tapani

2018-06-01

There has been growing interest towards naturalistic neuroimaging experiments, which deepen our understanding of how human brain processes and integrates incoming streams of multifaceted sensory information, as commonly occurs in real world. Music is a good example of such complex continuous phenomenon. In a few recent fMRI studies examining neural correlates of music in continuous listening settings, multiple perceptual attributes of music stimulus were represented by a set of high-level features, produced as the linear combination of the acoustic descriptors computationally extracted from the stimulus audio. NEW METHOD: fMRI data from naturalistic music listening experiment were employed here. Kernel principal component analysis (KPCA) was applied to acoustic descriptors extracted from the stimulus audio to generate a set of nonlinear stimulus features. Subsequently, perceptual and neural correlates of the generated high-level features were examined. The generated features captured musical percepts that were hidden from the linear PCA features, namely Rhythmic Complexity and Event Synchronicity. Neural correlates of the new features revealed activations associated to processing of complex rhythms, including auditory, motor, and frontal areas. Results were compared with the findings in the previously published study, which analyzed the same fMRI data but applied linear PCA for generating stimulus features. To enable comparison of the results, methodology for finding stimulus-driven functional maps was adopted from the previous study. Exploiting nonlinear relationships among acoustic descriptors can lead to the novel high-level stimulus features, which can in turn reveal new brain structures involved in music processing. Copyright © 2018 Elsevier B.V. All rights reserved.

Coastal barrier stratigraphy for Holocene high-resolution sea-level reconstruction

PubMed Central

Costas, Susana; Ferreira, Óscar; Plomaritis, Theocharis A.; Leorri, Eduardo

2016-01-01

The uncertainties surrounding present and future sea-level rise have revived the debate around sea-level changes through the deglaciation and mid- to late Holocene, from which arises a need for high-quality reconstructions of regional sea level. Here, we explore the stratigraphy of a sandy barrier to identify the best sea-level indicators and provide a new sea-level reconstruction for the central Portuguese coast over the past 6.5 ka. The selected indicators represent morphological features extracted from coastal barrier stratigraphy, beach berm and dune-beach contact. These features were mapped from high-resolution ground penetrating radar images of the subsurface and transformed into sea-level indicators through comparison with modern analogs and a chronology based on optically stimulated luminescence ages. Our reconstructions document a continuous but slow sea-level rise after 6.5 ka with an accumulated change in elevation of about 2 m. In the context of SW Europe, our results show good agreement with previous studies, including the Tagus isostatic model, with minor discrepancies that demand further improvement of regional models. This work reinforces the potential of barrier indicators to accurately reconstruct high-resolution mid- to late Holocene sea-level changes through simple approaches. PMID:27929122

Coastal barrier stratigraphy for Holocene high-resolution sea-level reconstruction.

PubMed

Costas, Susana; Ferreira, Óscar; Plomaritis, Theocharis A; Leorri, Eduardo

2016-12-08

The uncertainties surrounding present and future sea-level rise have revived the debate around sea-level changes through the deglaciation and mid- to late Holocene, from which arises a need for high-quality reconstructions of regional sea level. Here, we explore the stratigraphy of a sandy barrier to identify the best sea-level indicators and provide a new sea-level reconstruction for the central Portuguese coast over the past 6.5 ka. The selected indicators represent morphological features extracted from coastal barrier stratigraphy, beach berm and dune-beach contact. These features were mapped from high-resolution ground penetrating radar images of the subsurface and transformed into sea-level indicators through comparison with modern analogs and a chronology based on optically stimulated luminescence ages. Our reconstructions document a continuous but slow sea-level rise after 6.5 ka with an accumulated change in elevation of about 2 m. In the context of SW Europe, our results show good agreement with previous studies, including the Tagus isostatic model, with minor discrepancies that demand further improvement of regional models. This work reinforces the potential of barrier indicators to accurately reconstruct high-resolution mid- to late Holocene sea-level changes through simple approaches.

10 CFR 60.151 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Applicability. 60.151 Section 60.151 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Quality... to activities related thereto. These activities include: site characterization, facility and...

10 CFR 60.151 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Applicability. 60.151 Section 60.151 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Quality... to activities related thereto. These activities include: site characterization, facility and...

10 CFR 60.150 - Scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... components will perform satisfactorily in service. Quality assurance includes quality control, which... COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Quality Assurance § 60.150 Scope. As used in this part, quality assurance comprises all those planned and systematic...

Metabolic cross-talk between skeletal muscle and adipose tissue in high-intensity interval training vs. moderate-intensity continuous training by regulation of PGC-1α.

PubMed

Shirvani, Hossein; Arabzadeh, Ehsan

2018-02-26

An imbalance in the production of adipokines and myokines impairs the energy expenditure, increases adipocyte and develops metabolic pathologies. Physical exercise is able to regulate the secretion of myokines and adipokines. The present study considers the metabolic cross talk between skeletal muscle and adipose tissue in high-intensity interval training vs. moderate-intensity continuous training by regulation of PGC-1α. A sample of 32 male Wistar rats (8 weeks old with mean weight 250 ± 55 g) were divided into four groups randomly: control of base (CO), control of 8 weeks (CO8w), moderate-intensity continuous training (MICT), and high-intensity interval training (HIIT). The rats were fed with standard chow diet. The CO group was killed at the start of the study and the CO8w group was kept alive for the same time as the experimental groups, but did not participate in any exercise. MICT and HIIT groups for 8 weeks were placed under the moderate-intensity continuous training (15-60 min, with speed of 15-30 m/min) and high-intensity interval training (8-4 intense period for 1 min, with speed of 28-55 m/min, with 3-7 slow-intensity period for 1 min, with a speed of 12-30 m/min) for 8 weeks, respectively. To measure the levels of serum irisin, nesfatin, and resistin the ELISA method was used and real-time PCR method was used to evaluate the relative expression of soleus PGC-1α gene mRNA. The levels of irisin and nesfatin significantly increased in the HIIT compared with control groups (p = 0.001). Resistin values in both training groups showed a significant decrease compared to the control groups (p = 0.005). The level of PGC-1α gene expression in both HIIT and MICT groups was significantly increased in comparison with the control groups (p = 0.001). The results showed that HIIT and MICT increase the transcription of the PGC-1α gene and possibly the increased expression of this gene after HIIT and MICT plays a central role in the secretion of skeletal muscle myokines and adipokines of adipose tissue. No Level of evidence: Animal study.

Numerical Schemes for the Hamilton-Jacobi and Level Set Equations on Triangulated Domains

NASA Technical Reports Server (NTRS)

Barth, Timothy J.; Sethian, James A.

1997-01-01

Borrowing from techniques developed for conservation law equations, numerical schemes which discretize the Hamilton-Jacobi (H-J), level set, and Eikonal equations on triangulated domains are presented. The first scheme is a provably monotone discretization for certain forms of the H-J equations. Unfortunately, the basic scheme lacks proper Lipschitz continuity of the numerical Hamiltonian. By employing a virtual edge flipping technique, Lipschitz continuity of the numerical flux is restored on acute triangulations. Next, schemes are introduced and developed based on the weaker concept of positive coefficient approximations for homogeneous Hamiltonians. These schemes possess a discrete maximum principle on arbitrary triangulations and naturally exhibit proper Lipschitz continuity of the numerical Hamiltonian. Finally, a class of Petrov-Galerkin approximations are considered. These schemes are stabilized via a least-squares bilinear form. The Petrov-Galerkin schemes do not possess a discrete maximum principle but generalize to high order accuracy.

Effects of Changing Stress Amplitude on the Rate of Fatigue-Crack Propagation in Two Aluminum Alloys

NASA Technical Reports Server (NTRS)

Hudson, C. Michael; Hardrath, Herbert F.

1961-01-01

A series of fatigue tests with specimens subjected to constant amplitude and two-step axial loads were conducted on 12-inch-wide sheet specimens of 2024-T3 and 7075-T6 aluminum alloy to study the effects of a change in stress level on fatigue-crack propagation. Comparison of the results of the tests in which the specimens were tested at first a high and then a low stress level with those of the constant-stress- amplitude tests indicated that crack propagation was generally delayed after the transition to the lower stress level. In the tests in which the specimens were tested at first a low and then a high stress level, crack propagation continued at the expected rate after the change in stress levels.

Developmental trajectories of marital happiness in continuously married individuals: a group-based modeling approach.

PubMed

Anderson, Jared R; Van Ryzin, Mark J; Doherty, William J

2010-10-01

Most contemporary studies of change in marital quality over time have used growth curve modeling to describe continuously declining mean curves. However, there is some evidence that different trajectories of marital quality exist for different subpopulations. Group-based trajectory modeling provides the opportunity to conduct an empirical investigation of the variance in marital quality trajectories. We applied this method to analyze data from continuously married individuals from the Marital Instability over the Life Course Study (N = 706). Instead of a single continuously declining trajectory of marital happiness, we found 5 distinct trajectories. Nearly two thirds of participants reported high and stable levels of happiness over time, and the other one third showed either a pattern of continuous low happiness, low happiness that subsequently declined, or a curvilinear pattern of high happiness, decline, and recovery. Marital problems, time spent in shared activities, and (to a lesser degree) economic hardship were able to distinguish trajectory group membership. Our results suggest that marital happiness may have multiple distinct trajectories across reasonably diverse populations. Implications for theory, research, and practice are discussed.

Continuing education: the 1998 Survey of the Royal Australasian College of Dental Surgeons.

PubMed

Sambrook, P; Thomson, D; Bastiaan, R; Goss, A

2001-06-01

Continuing education (CE) is an essential professional activity. In the last decade, CE has been actively pursued by the medical profession in Australia and abroad. However, the uptake of CE in dentistry has been much slower and there is minimal Australian data on dental CE. To determine the level of CE activity, in 1998, postal questionnaires were sent to all fellows of the Royal Australasian College of Dental Surgeons. The responses were analysed. There was a high response rate (90 per cent) but a moderate usable rate (54 per cent). The results show a biphasic distribution between high and low CE activity. The average amount of activity of those involved in CE was 116 hours per year, above the usually accepted minimum of 100 hours/year. Some groups, particularly members of the specialist divisions of oral and maxillofacial surgeons (215 hours) and periodontists (205 hours), have high levels of CE. However, approximately 25 per cent of college fellows reported little or no CE activity. The survey revealed that inactive fellows are more likely to be older and in general practice. Inactive fellows were also tardy in replying to the questionnaire. The high activity CE group needs to be recognised and encouraged to continue. Specific plans to help the low CE activity group should be developed. Although these findings relate directly to the Royal Australasian College of Dental Surgeons, they are presented as they have implications for the dental profession at large.

Effects of High-Intensity Interval Training on Aerobic Capacity in Cardiac Patients: A Systematic Review with Meta-Analysis

PubMed Central

Xie, Bin; Yan, Xianfeng

2017-01-01

Purpose. The aim of this study was to compare the effects of high-intensity interval training (INTERVAL) and moderate-intensity continuous training (CONTINUOUS) on aerobic capacity in cardiac patients. Methods. A meta-analysis identified by searching the PubMed, Cochrane Library, EMBASE, and Web of Science databases from inception through December 2016 compared the effects of INTERVAL and CONTINUOUS among cardiac patients. Results. Twenty-one studies involving 736 participants with cardiac diseases were included. Compared with CONTINUOUS, INTERVAL was associated with greater improvement in peak VO2 (mean difference 1.76 mL/kg/min, 95% confidence interval 1.06 to 2.46 mL/kg/min, p < 0.001) and VO2 at AT (mean difference 0.90 mL/kg/min, 95% confidence interval 0.0 to 1.72 mL/kg/min, p = 0.03). No significant difference between the INTERVAL and CONTINUOUS groups was observed in terms of peak heart rate, peak minute ventilation, VE/VCO2 slope and respiratory exchange ratio, body mass, systolic or diastolic blood pressure, triglyceride or low- or high-density lipoprotein cholesterol level, flow-mediated dilation, or left ventricular ejection fraction. Conclusions. This study showed that INTERVAL improves aerobic capacity more effectively than does CONTINUOUS in cardiac patients. Further studies with larger samples are needed to confirm our observations. PMID:28386556

The effects of free-living interval-walking training on glycemic control, body composition, and physical fitness in type 2 diabetic patients: a randomized, controlled trial.

PubMed

Karstoft, Kristian; Winding, Kamilla; Knudsen, Sine H; Nielsen, Jens S; Thomsen, Carsten; Pedersen, Bente K; Solomon, Thomas P J

2013-02-01

To evaluate the feasibility of free-living walking training in type 2 diabetic patients and to investigate the effects of interval-walking training versus continuous-walking training upon physical fitness, body composition, and glycemic control. Subjects with type 2 diabetes were randomized to a control (n = 8), continuous-walking (n = 12), or interval-walking group (n = 12). Training groups were prescribed five sessions per week (60 min/session) and were controlled with an accelerometer and a heart-rate monitor. Continuous walkers performed all training at moderate intensity, whereas interval walkers alternated 3-min repetitions at low and high intensity. Before and after the 4-month intervention, the following variables were measured: VO(2)max, body composition, and glycemic control (fasting glucose, HbA(1c), oral glucose tolerance test, and continuous glucose monitoring [CGM]). Training adherence was high (89 ± 4%), and training energy expenditure and mean intensity were comparable. VO(2)max increased 16.1 ± 3.7% in the interval-walking group (P < 0.05), whereas no changes were observed in the continuous-walking or control group. Body mass and adiposity (fat mass and visceral fat) decreased in the interval-walking group only (P < 0.05). Glycemic control (elevated mean CGM glucose levels and increased fasting insulin) worsened in the control group (P < 0.05), whereas mean (P = 0.05) and maximum (P < 0.05) CGM glucose levels decreased in the interval-walking group. The continuous walkers showed no changes in glycemic control. Free-living walking training is feasible in type 2 diabetic patients. Continuous walking offsets the deterioration in glycemia seen in the control group, and interval walking is superior to energy expenditure-matched continuous walking for improving physical fitness, body composition, and glycemic control.

Prolonged continuous exposure to high fine particulate matter associated with cardiovascular and respiratory disease mortality in Beijing, China

NASA Astrophysics Data System (ADS)

Wang, Jinfeng; Yin, Qian; Tong, Shilu; Ren, Zhoupeng; Hu, Maogui; Zhang, Hongrui

2017-11-01

Although many studies examined the effects of fine particulate matter (PM2.5) on the deaths of cardiovascular disease (CVD) and respiratory disease (RD), few research has paid attention to the effects of prolonged continuous exposure to high PM2.5 pollution. This study estimated the excess risks (ER) of CVD and RD mortalities associated with prolonged continuous exposure to high PM2.5 pollution for the whole population and specific subsociodemographic groups in Beijing, which is the capital city of China with over 20 million residents and having severe PM2.5 pollution problems. Our results suggested that when high PM2.5 pollution occurred continuously, at various thresholds and durations, the adverse effects on CVD and RD mortalities varied significantly. The CVD mortality risks in association with prolonged continuous high PM2.5 pollution exposure were more serious for single individuals (including unmarried, divorced, and widowed), illiterate and outdoor workers than for other specific subsociodemographic groups. When the daily PM2.5 concentration higher than 105 μg/m3 consecutively occurs, at the ninth day, the ERs of CVD death for single individuals, illiterate and outdoor workers groups reached to 45% (95% CI: 22, 71), 51% (95% CI: 28, 79) and 53% (95% CI: 29, 82) respectively. On the other hand, prolonged continuous high PM2.5 pollution level appeared to contribute a higher proportion of RD deaths among illiterate and outdoor workers, but less significant for the other specific subsociodemographic groups. When the duration with daily PM2.5 pollution higher than 115 μg/m3 reached to six days, the ERs for outdoor workers and illiterate attributed to prolonged continuous PM2.5 pollution exposure increased 36% (95% CI: 5, 76) and 49% (95% CI: 16, 91) respectively.

An Overview of Educational Technologies and Implications for Staff Development at the Community College Level.

ERIC Educational Resources Information Center

Self, Charles C.

The need for and uses of high technology delivery systems in education are discussed in this paper with respect to the community college level. After part I introduces the topic, part II links the need for new technology in education to the change in the nature of knowledge from a small, relatively static corpus to a large and continually changing…

Examining the Effects of General Level Course Elimination and Tracking on Student Growth and Achievement in a Suburban High School Mathematics Program

ERIC Educational Resources Information Center

Ellis, Brian E.

2014-01-01

Despite a decade of reform driven by the NCLB legislation, there continues to be a significant gap in mathematics achievement between race/ethnicity and socioeconomic groupings of students. This study examines the practice of tracking and an effort to improve mathematics achievement by eliminating the general level mathematics track. The suburban…

A Human Serum-Based Enzyme-Free Continuous Glucose Monitoring Technique Using a Needle-Type Bio-Layer Interference Sensor.

PubMed

Seo, Dongmin; Paek, Sung-Ho; Oh, Sangwoo; Seo, Sungkyu; Paek, Se-Hwan

2016-09-24

The incidence of diabetes is continually increasing, and by 2030, it is expected to have increased by 69% and 20% in underdeveloped and developed countries, respectively. Therefore, glucose sensors are likely to remain in high demand in medical device markets. For the current study, we developed a needle-type bio-layer interference (BLI) sensor that can continuously monitor glucose levels. Using dialysis procedures, we were able to obtain hypoglycemic samples from commercial human serum. These dialysis-derived samples, alongside samples of normal human serum were used to evaluate the utility of the sensor for the detection of the clinical interest range of glucose concentrations (70-200 mg/dL), revealing high system performance for a wide glycemic state range (45-500 mg/dL). Reversibility and reproducibility were also tested over a range of time spans. Combined with existing BLI system technology, this sensor holds great promise for use as a wearable online continuous glucose monitoring system for patients in a hospital setting.

Ion release from dental casting alloys as assessed by a continuous flow system: Nutritional and toxicological implications.

PubMed

López-Alías, José F; Martinez-Gomis, Jordi; Anglada, Josep M; Peraire, Maria

2006-09-01

The aims of this study were to quantify the metallic ions released by various dental alloys subjected to a continuous flow of saliva and to estimate the nutritional and toxicological implications of such a release. Four pieces of three nickel-based, one noble, one high-noble and two copper-aluminum alloys were cast and then immersed in a continuous flow of artificial saliva for 15 days. To simulate three meals a day, casts were subjected to thrice-daily episodes, lasting 30 min each and consisting of pH decreases and salinity increases. After 15 days, the metallic ions in the artificial saliva were analyzed. Data were expressed as averaged release rate: microg/cm2/day of ion released for each alloy. The highest value of 95% Cl of each ion was adapted to a hypothetical worst scenario of a subject with 100 cm2 of exposed metal surface. The results were compared with the tolerable upper daily intake level of each ion. The copper-aluminum alloys released copper, aluminum, nickel, manganese and iron. The nickel-based alloys essentially released nickel and chromium, while the beryllium-containing alloy released beryllium and significantly more nickel. The noble and high-noble alloys were very resistant to corrosion. The amount of ions released remained far below the upper tolerable intake level, with the exception of nickel, released by beryllium-containing nickel-based alloy, whose levels approach 50% of this threshold. The daily amount of ions released seems to be far below the tolerable upper intake levels for each ion.

The forgotten smoker: a qualitative study of attitudes towards smoking, quitting, and tobacco control policies among continuing smokers.

PubMed

Uppal, Navneet; Shahab, Lion; Britton, John; Ratschen, Elena

2013-05-03

Although research suggests that the majority of smokers want to quit smoking, the uptake of Stop Smoking Services, designed to assist smokers with quitting, remains low. Little is known about continuing smokers who do not access these services, and opportunities to influence their motivation and encourage quit attempts through the uptake of services. Using PRIME theory, this study explored differences between continuing smokers who had varying levels of motivation to quit, in terms of their plans to quit, evaluative beliefs about smoking, cigarette dependence, and attitudes towards tobacco control policies and services. Twenty-two current smokers, recruited from the community, were classified by motivation level to quit using a self-report questionnaire (two groups: high/low). Four focus groups (n=13) and individual interviews (n=9) were conducted with both groups using an interview guide incorporating aspects of PRIME theory. Discussion areas included motives for smoking, attitudes towards smoking and quitting, perceptions of dependence, motives for quitting, barriers to quitting, and attitudes towards existing and impending tobacco control policies and services. Verbatim transcripts were analysed using thematic framework analysis. All participants expressed low motivation to quit during discussions, despite some initially self-classifying as having high explicit levels of motivation to quit. Both groups reported similar attitudes towards smoking and quitting, including a perceived psychological addiction to smoking, positive evaluations about smoking which inhibited plans to quit, and similar suggested methods to increase motivation (simply wanting to, save money, improve health). Most felt that they 'ought' to quit as opposed to 'wanted' to. Little influence was ascribed towards tobacco control policies such as plain packaging and hidden sales displays, and participants felt that price increases of tobacco products needed to be considerable in order to influence motivation. Highly motivated smokers expressed more willingness to visit Stop Smoking Services, although none had done so. Continuing smokers' attitudes towards smoking and quitting suggests that research and policy need to focus on increasing smokers' implicit motivation to quit smoking, even for those who classified themselves as having high motivation to quit. Targeted information and further education about Stop Smoking Services is required to increase uptake.

Towards an implantable bio-sensor platform for continuous real-time monitoring of anti-epileptic drugs.

PubMed

Hammoud, Abbas; Chamseddine, Ahmad; Nguyen, Dang K; Sawan, Mohamad

2016-08-01

The need of continuous real-time monitoring device for in-vivo drug level detection has been widely articulated lately. Such monitoring could guide drug posology and timing of intake, detect low or high drug levels, in order to take adequate measures, and give clinicians a valuable window into patients' health and their response to therapeutics. This paper presents a novel implantable bio-sensor based on impedance measurement capable of continuously monitoring various antiepileptic drug levels. This portable point-of-care microsystem replaces large and stationary conventional macrosystems, and is a one of a kind system designed with an array of electrodes to monitor various anti-epileptic drugs rather than one drug. The micro-system consists of (i) the front-end circuit including an inductive coil to receive energy from an external base station, and to exchange data with the latter; (ii) the power management block; (iii) the readout and control block; and (iv) the biosensor array. The electrical circuitry was designed using the 0.18-um CMOS process technology intended to be miniature and consume ultra-low power.

Intergenerational continuity of child abuse among adolescent mothers: authoritarian parenting, community violence, and race.

PubMed

Valentino, Kristin; Nuttall, Amy K; Comas, Michelle; Borkowski, John G; Akai, Carol E

2012-05-01

Among the negative sequelae of child maltreatment is increased risk for continuity of maltreatment into subsequent generations. Despite acknowledgment in the literature that the pathways toward breaking the cycle of maltreatment are likely the result of dynamic interactions of risk and protective factors across multiple ecological levels, few studies have followed high-risk samples of maltreated and nonmaltreated parents over time to evaluate such processes. In the current investigation, exposure to community violence and authoritarian parenting attitudes were evaluated as predictors of the intergenerational continuity of abuse, and the moderating effect of African American race was examined. The sample included 70 mothers and their 18-year-old children, who have been followed longitudinally since the third trimester of the adolescent mothers' pregnancy. Results revealed that among mothers with a child abuse history, higher exposure to community violence and lower authoritarian parenting attitudes were associated with increased risk for intergenerational continuity of abuse. The relation of authoritarian parenting attitudes to intergenerational continuity was moderated by race; the protective effects of authoritarian parenting were limited to the African American families only. The salience of multiple ecological levels in interrupting the intergenerational continuity of child abuse is discussed, and implications for preventive programs are highlighted.

10 CFR 60.71 - Records and reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Records... the Energy Reorganization Act. (b) Records of the receipt, handling, and disposition of radioactive waste at a geologic repository operations area shall contain sufficient information to provide a...

10 CFR 60.4 - Communications and records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC... offices at 11555 Rockville Pike, Rockville, Maryland; or, where practicable, by electronic submission, for example, via Electronic Information Exchange, or CD-ROM. Electronic submissions must be made in a manner...

40 CFR 63.1975 - How do I calculate the 3-hour block average used to demonstrate compliance?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Waste Landfills General and Continuing Compliance Requirements § 63.1975 How do I calculate the 3-hour... subpart: (a) Monitoring system breakdowns, repairs, calibration checks, and zero (low-level) and high...

10 CFR 60.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General..., special nuclear, and byproduct material at a geologic repository operations area sited, constructed, or... at a geologic repository operations area sited, constructed, or operated at Yucca Mountain, Nevada...

10 CFR 60.15 - Site characterization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses... the geologic repository to the extent practical. (2) The number of exploratory boreholes and shafts... characterization. (3) To the extent practical, exploratory boreholes and shafts in the geologic repository...

40 CFR 191.12 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Definitions. 191.12 Section 191.12 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.01 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Applicability. 191.01 Section 191.01 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.03 - Standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Standards. 191.03 Section 191.03 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.01 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Applicability. 191.01 Section 191.01 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.03 - Standards.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Standards. 191.03 Section 191.03 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.11 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Applicability. 191.11 Section 191.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.22 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Definitions. 191.22 Section 191.22 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.03 - Standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Standards. 191.03 Section 191.03 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.02 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Definitions. 191.02 Section 191.02 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.21 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Applicability. 191.21 Section 191.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.01 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Applicability. 191.01 Section 191.01 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.21 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Applicability. 191.21 Section 191.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.11 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Applicability. 191.11 Section 191.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.21 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Applicability. 191.21 Section 191.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.11 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Applicability. 191.11 Section 191.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.22 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Definitions. 191.22 Section 191.22 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.03 - Standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Standards. 191.03 Section 191.03 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.01 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Applicability. 191.01 Section 191.01 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.21 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Applicability. 191.21 Section 191.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.11 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Applicability. 191.11 Section 191.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.22 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Definitions. 191.22 Section 191.22 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

10 CFR 60.15 - Site characterization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... in situ testing before and during construction shall be planned and coordinated with geologic... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses... be described in such application. (b) Unless the Commission determines with respect to the site...

10 CFR 60.15 - Site characterization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... in situ testing before and during construction shall be planned and coordinated with geologic... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses... be described in such application. (b) Unless the Commission determines with respect to the site...

10 CFR 60.15 - Site characterization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... in situ testing before and during construction shall be planned and coordinated with geologic... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses... be described in such application. (b) Unless the Commission determines with respect to the site...

10 CFR 60.15 - Site characterization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... in situ testing before and during construction shall be planned and coordinated with geologic... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses... be described in such application. (b) Unless the Commission determines with respect to the site...

10 CFR 60.31 - Construction authorization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Construction authorization. 60.31 Section 60.31 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.31 Construction authorization. Upon review and...

10 CFR 60.31 - Construction authorization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Construction authorization. 60.31 Section 60.31 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.31 Construction authorization. Upon review and...

INSTALLATION OF A POST-ACCIDENT CONFINEMENT HIGH-LEVEL RADIATION MONITORING SYSTEM IN THE KOLA NUCLEAR POWER STATION (UNIT 2) IN RUSSIA

DOE Office of Scientific and Technical Information (OSTI.GOV)

GREENE,G.A.; GUPPY,J.G.

1998-09-01

This is the final report on the INSP project entitled, ``Post-Accident Confinement High-Level Radiation Monitoring System'' conducted by BNL under the authorization of Project Work Plan WBS 1.2.2.6 (Attachment 1). This project was initiated in February 1993 to assist the Russians in reducing risks associated with the continued operation of older Soviet-designed nuclear power plants, specifically the Kola VVER-440/230 Unit 2, through improved accident detection capability, specifically by the installation of a dual train high-level radiation detection system in the confinement of Unit 2 of the Kola NPP. The major technical objective of this project was to provide, install andmore » make operational the necessary hardware inside the confinement of the Kola NPP Unit 2 to provide early and reliable warning of the release of radionuclides from the reactor into the confinement air space as an indication of the occurrence of a severe accident at the plant. In addition, it was intended to provide hands-on experience and training to the Russian plant workers in the installation, operation, calibration and maintenance of the equipment in order that they may use the equipment without continued US assistance as an effective measure to improve reactor safety at the plant.« less

Characteristics of women who continue smoking during pregnancy: a cross-sectional study of pregnant women and new mothers in 15 European countries

PubMed Central

2014-01-01

Background Some women continue smoking during pregnancy despite the extensive information available on the dangers smoking poses to their fetus. This study aimed to examine the prevalence and determinants of smoking before and during pregnancy and the extent of smoking during pregnancy from a European perspective in relation to maternal sociodemographic characteristics, health literacy, morbidity, and pregnancy-related factors. Methods This multinational, web-based study evaluated pregnant women and new mothers in 15 European countries recruited from October 2011 to February 2012. Data were collected via an anonymous online questionnaire. Results Of 8344 women included, 2944 (35.3%) reported smoking before pregnancy, and 771 (26.2%) continued smoking during pregnancy, 88 (11.4%) of whom smoked more than 10 cigarettes per day. There was a wide variation among the 15 European countries in smoking rates before and during pregnancy, ranging from 25.0% (Sweden) to 50.0% (Croatia) before and 4.2% (Iceland) to 18.9% (Croatia) during pregnancy. Women who lived in Eastern Europe, without a spouse/partner, with a low education level and unplanned pregnancy, who did not take folic acid, and consumed alcohol during pregnancy were the most likely to smoke before pregnancy. Women who lived in Eastern or Western Europe, without a spouse/partner, with a low education level and health literacy, being a housewife, having previous children and unplanned pregnancy, and who did not take folic acid were the most likely to continue smoking during pregnancy. Women who smoked more than 10 cigarettes per day during pregnancy were the most likely to be living in Eastern Europe and to have a low education level. Conclusion Women with fewer resources living in Western or Eastern Europe are more likely not only to smoke before pregnancy but also to continue smoking during pregnancy. These high-risk women are characterized as living alone, having high school or less as highest education level, having low health literacy, being a housewife, having previous children, having unplanned pregnancy, and no use of folic acid. Our findings indicated that focus on smoking cessation is important in antenatal care in Europe as many women smoke before pregnancy, and still continue to do so in pregnancy. PMID:24964728

Characterization of vitamin D3 metabolites using continuous-flow fast atom bombardment tandem mass spectrometry and high-performance liquid chromatography.

PubMed

Yeung, B; Vouros, P; Reddy, G S

1993-08-13

A mass spectrometric method for the detection of vitamin D3 metabolites is described. This method involves the derivatization of the metabolites by cycloaddition with 4-phenyl-1,2,4-triazoline-3,5-dione, followed by their characterization by continuous-flow fast atom bombardment (CF-FAB) tandem mass spectrometry (MS-MS) and high-performance liquid chromatography (HPLC). Using HPLC, this derivatization has been shown to increase the UV detectability of 25-hydroxyvitamin D3 by about 5-fold. The FAB spectra of the adducts are dominated by peaks corresponding to a protonated molecule and a fragment ion derived in part from the loss of the side chain. Multiple reaction monitoring (MRM) of this transition by MS-MS may be utilized for trace level analysis of vitamin D metabolites. Sample introduction by flow injection yields detection limits in the low nanogram to high picogram range, whereas the use of on-line capillary LC has been found to decrease the detection limits to the low picogram level.

Predictors of Global Self-Worth and Academic Performance among Regular Education, Learning Disabled, and Continuation High School Students.

ERIC Educational Resources Information Center

Wiest, Dudley J.; Wong, Eugene H.; Kreil, Dennis A.

1998-01-01

The ability of measures of perceived competence, control, and autonomy support to predict self-worth and academic performance was studied across groups of high school students. Stepwise regression analyses indicate these variables in model predict self-worth and grade point average. In addition, levels of school status and depression predict…

A Quantitative Comparison of Pennsylvania High School Student Achievement by Middle States Association's Accreditation Status

ERIC Educational Resources Information Center

Johnson, Christopher A.

2012-01-01

As public school accountability for student achievement has continued to increase, prior to and as a result of the No Child Left Behind Act of 2001, schools have sought ways of bringing new instructional services to their students to raise their levels of achievement. Some Pennsylvania public high schools have attempted to improve student…

Surviving at the Street Level: How Counselors' Implementation of School Choice Policy Shapes Students' High School Destinations

ERIC Educational Resources Information Center

Sattin-Bajaj, Carolyn; Jennings, Jennifer L.; Corcoran, Sean P.; Baker-Smith, Elizabeth Christine; Hailey, Chantal

2018-01-01

Given the dominance of residentially based school assignment, prior researchers have conceptualized K-12 enrollment decisions as beyond the purview of school actors. This paper questions the continued relevance of this assumption by studying the behavior of guidance counselors charged with implementing New York City's universal high school choice…

Identifying Characteristics of High School Dropouts: Data Mining with A Decision Tree Model

ERIC Educational Resources Information Center

Veitch, William Robert.

2004-01-01

The notion that all students should finish high school has grown throughout the last century and continues to be an important goal for all educational levels in this new century. Non-completion has been related to all sorts of social, financial, and psychological issues. Many studies have attempted to put together a process that will identify…

A Collaborative Project to Increase the Participation of Women and Minorities in Higher Level Mathematics Courses

ERIC Educational Resources Information Center

Kennedy, Kristin; Schumacher, Phyllis

2005-01-01

In this article, the authors describe a program developed to encourage women and minorities to continue their study of mathematics in high schools until graduation. The 3-year program was a collaborative effort by professors and students from Bryant University, local businesses, and local high schools. During the 3 years, the program evolved from…

Principals as Teacher Leaders in the Kentucky Education Reform Act Era: Laying the Groundwork for High-Achieving, Low Income Schools.

ERIC Educational Resources Information Center

McDonald, Deborah Halcomb; Keedy, John L.

This research examined how three elementary school principals conceptualized within the Kentucky Education Reform Act (KERA) of 1990 the development of teacher leaders. Two major criteria were used to select these principals: (a) their schools had continuous student achievement for three consecutive biennia despite high levels of student poverty;…

Using a Laboratory Inquiry with High School Students to Determine the Reaction Stoichiometry of Neutralization by a Thermochemical Approach

ERIC Educational Resources Information Center

Journal of Chemical Education, 2015

2015-01-01

This paper presents the design and practical application of a laboratory inquiry at high school chemistry level for systematic chemistry learning, as exemplified by a thermochemical approach to the reaction stoichiometry of neutralization using Job's method of continuous variation. In the laboratory inquiry, students are requested to propose the…

High Precision Continuous and Real-Time Measurement of Atmospheric Oxygen Using Cavity Ring-Down Spectroscopy.

NASA Astrophysics Data System (ADS)

Kim-Hak, D.; Hoffnagle, J.; Rella, C.; Sun, M.

2016-12-01

Oxygen is a major and vital component of the Earth atmosphere representing about 21% of its composition. It is consumed or produced through biochemical processes such as combustion, respiration, and photosynthesis. Although atmospheric oxygen is not a greenhouse gas, it can be used as a top-down constraint on the carbon cycle. The variation observations of oxygen in the atmosphere are very small, in the order of the few ppm's. This presents the main technical challenge for measurement as a very high level of precision is required and only few methods including mass spectrometry, fuel cell, and paramagnetic are capable of overcoming it. Here we present new developments of a high-precision gas analyzer that utilizes the technique of Cavity Ring-Down Spectroscopy to measure oxygen concentration and oxygen isotope. Its compact and ruggedness design combined with high precision and long-term stability allows the user to deploy the instrument in the field for continuous monitoring of atmospheric oxygen level. Measurements have a 1-σ 5-minute averaging precision of 1-2 ppm for O2 over a dynamic range of 0-20%. We will present supplemental data acquired from our 10m tower measurements in Santa Clara, CA.

Subseasonal to Seasonal Predictions of U.S. West Coast High Water Levels

NASA Astrophysics Data System (ADS)

Khouakhi, A.; Villarini, G.; Zhang, W.; Slater, L. J.

2017-12-01

Extreme sea levels pose a significant threat to coastal communities, ecosystems, and assets, as they are conducive to coastal flooding, coastal erosion and inland salt-water intrusion. As sea levels continue to rise, these sea level extremes - including occasional minor coastal flooding experienced during high tide (nuisance floods) - are of concern. Extreme sea levels are increasing at many locations around the globe and have been attributed largely to rising mean sea levels associated with intra-seasonal to interannual climate processes such as the El Niño-Southern Oscillation (ENSO). Here, intra-seasonal to seasonal probabilistic forecasts of high water levels are computed at the Toke Point tide gage station on the US west coast. We first identify the main climate drivers that are responsible for high water levels and examine their predictability using General Circulation Models (GCMs) from the North American Multi-Model Ensemble (NMME). These drivers are then used to develop a probabilistic framework for the seasonal forecasting of high water levels. We focus on the climate controls on the frequency of high water levels using the number of exceedances above the 99.5th percentile and above the nuisance flood level established by the National Weather Service. Our findings indicate good forecast skill at the shortest lead time, with the skill that decreases as we increase the lead time. In general, these models aptly capture the year-to-year variability in the observational records.

Advances in high power linearly polarized fiber laser and its application

NASA Astrophysics Data System (ADS)

Zhou, Pu; Huang, Long; Ma, Pengfei; Xu, Jiangming; Su, Rongtao; Wang, Xiaolin

2017-10-01

Fiber lasers are now attracting more and more research interest due to their advantages in efficiency, beam quality and flexible operation. Up to now, most of the high power fiber lasers have random distributed polarization state. Linearlypolarized (LP) fiber lasers, which could find wide application potential in coherent detection, coherent/spectral beam combining, nonlinear frequency conversion, have been a research focus in recent years. In this paper, we will present a general review on the achievements of various kinds of high power linear-polarized fiber laser and its application. The recent progress in our group, including power scaling by using power amplifier with different mechanism, high power linearly polarized fiber laser with diversified properties, and various applications of high power linear-polarized fiber laser, are summarized. We have achieved 100 Watt level random distributed feedback fiber laser, kilowatt level continuous-wave (CW) all-fiber polarization-maintained fiber amplifier, 600 watt level average power picosecond polarization-maintained fiber amplifier and 300 watt level average power femtosecond polarization-maintained fiber amplifier. In addition, high power linearly polarized fiber lasers have been successfully applied in 5 kilowatt level coherent beam combining, structured light field and ultrasonic generation.

A quantitative method for optimized placement of continuous air monitors.

PubMed

Whicker, Jeffrey J; Rodgers, John C; Moxley, John S

2003-11-01

Alarming continuous air monitors (CAMs) are a critical component for worker protection in facilities that handle large amounts of hazardous materials. In nuclear facilities, continuous air monitors alarm when levels of airborne radioactive materials exceed alarm thresholds, thus prompting workers to exit the room to reduce inhalation exposures. To maintain a high level of worker protection, continuous air monitors are required to detect radioactive aerosol clouds quickly and with good sensitivity. This requires that there are sufficient numbers of continuous air monitors in a room and that they are well positioned. Yet there are no published methodologies to quantitatively determine the optimal number and placement of continuous air monitors in a room. The goal of this study was to develop and test an approach to quantitatively determine optimal number and placement of continuous air monitors in a room. The method we have developed uses tracer aerosol releases (to simulate accidental releases) and the measurement of the temporal and spatial aspects of the dispersion of the tracer aerosol through the room. The aerosol dispersion data is then analyzed to optimize continuous air monitor utilization based on simulated worker exposure. This method was tested in a room within a Department of Energy operated plutonium facility at the Savannah River Site in South Carolina, U.S. Results from this study show that the value of quantitative airflow and aerosol dispersion studies is significant and that worker protection can be significantly improved while balancing the costs associated with CAM programs.

High temperature metal hydrides as heat storage materials for solar and related applications.

PubMed

Felderhoff, Michael; Bogdanović, Borislav

2009-01-01

For the continuous production of electricity with solar heat power plants the storage of heat at a temperature level around 400 degrees C is essential. High temperature metal hydrides offer high heat storage capacities around this temperature. Based on Mg-compounds, these hydrides are in principle low-cost materials with excellent cycling stability. Relevant properties of these hydrides and their possible applications as heat storage materials are described.

High Temperature Metal Hydrides as Heat Storage Materials for Solar and Related Applications

PubMed Central

Felderhoff, Michael; Bogdanović, Borislav

2009-01-01

For the continuous production of electricity with solar heat power plants the storage of heat at a temperature level around 400 °C is essential. High temperature metal hydrides offer high heat storage capacities around this temperature. Based on Mg-compounds, these hydrides are in principle low-cost materials with excellent cycling stability. Relevant properties of these hydrides and their possible applications as heat storage materials are described. PMID:19333448

10 CFR 63.4 - Communications and records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC..., Office of Nuclear Material Safety and Safeguards; or, (3) Where practicable, by electronic submission, for example, via Electronic Information Exchange, or CD-ROM. Electronic submissions must be made in a...

10 CFR 63.4 - Communications and records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC..., Office of Nuclear Material Safety and Safeguards; or, (3) Where practicable, by electronic submission, for example, via Electronic Information Exchange, or CD-ROM. Electronic submissions must be made in a...

10 CFR 63.4 - Communications and records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC..., Office of Nuclear Material Safety and Safeguards; or, (3) Where practicable, by electronic submission, for example, via Electronic Information Exchange, or CD-ROM. Electronic submissions must be made in a...

Targeted Support

ERIC Educational Resources Information Center

Simon, Gabe

2011-01-01

Heritage Oak Elementary School (Placer County, CA) has continuously achieved a high level of academic success as measured by the California Standards Test. However, after examining student testing data in depth, staff discovered a large achievement gap between the overall school population, socio-economically disadvantaged students, and students…

10 CFR 60.5 - Interpretations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Interpretations. 60.5 Section 60.5 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.5 Interpretations. Except as specifically authorized by the Commission, in writing, no...

10 CFR 60.5 - Interpretations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Interpretations. 60.5 Section 60.5 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.5 Interpretations. Except as specifically authorized by the Commission, in writing, no...

10 CFR 60.5 - Interpretations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Interpretations. 60.5 Section 60.5 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.5 Interpretations. Except as specifically authorized by the Commission, in writing, no...

10 CFR 60.33 - Amendment of construction authorization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Amendment of construction authorization. 60.33 Section 60.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.33 Amendment of construction authorization...

10 CFR 60.5 - Interpretations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Interpretations. 60.5 Section 60.5 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.5 Interpretations. Except as specifically authorized by the Commission, in writing, no...

10 CFR 60.162 - Physical requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Physical requirements. 60.162 Section 60.162 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Training and Certification of Personnel § 60.162 Physical requirements. The physical condition and...

10 CFR 60.162 - Physical requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Physical requirements. 60.162 Section 60.162 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Training and Certification of Personnel § 60.162 Physical requirements. The physical condition and...

10 CFR 60.162 - Physical requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Physical requirements. 60.162 Section 60.162 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Training and Certification of Personnel § 60.162 Physical requirements. The physical condition and...

10 CFR 60.162 - Physical requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Physical requirements. 60.162 Section 60.162 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Training and Certification of Personnel § 60.162 Physical requirements. The physical condition and...

40 CFR 191.05 - Effective date.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Effective date. 191.05 Section 191.05 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.27 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Effective date. 191.27 Section 191.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.17 - Effective date.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Effective date. 191.17 Section 191.17 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.27 - Effective date.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Effective date. 191.27 Section 191.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.27 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Effective date. 191.27 Section 191.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.27 - Effective date.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Effective date. 191.27 Section 191.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.05 - Effective date.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Effective date. 191.05 Section 191.05 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.05 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Effective date. 191.05 Section 191.05 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.17 - Effective date.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Effective date. 191.17 Section 191.17 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.27 - Effective date.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Effective date. 191.27 Section 191.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.05 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Effective date. 191.05 Section 191.05 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.17 - Effective date.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Effective date. 191.17 Section 191.17 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.17 - Effective date.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Effective date. 191.17 Section 191.17 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

40 CFR 191.17 - Effective date.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Effective date. 191.17 Section 191.17 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR MANAGEMENT AND DISPOSAL OF SPENT NUCLEAR FUEL, HIGH-LEVEL AND...

A Clinical Implant Program in the Predoctoral Curriculum.

ERIC Educational Resources Information Center

Bell, Fred A.; And Others

1991-01-01

Six senior dental students participated in a preprosthetic surgery clinic and then performed implant surgery on patients. Patient reactions were highly favorable. Students and faculty found the prosthodontic phase more difficult than the surgical. Program continuation at the predoctoral level is anticipated. (MSE)

10 CFR 63.131 - General requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA... conditions encountered and changes in those conditions during construction and waste emplacement operations...

10 CFR 63.131 - General requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA... conditions encountered and changes in those conditions during construction and waste emplacement operations...

10 CFR 63.131 - General requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA... conditions encountered and changes in those conditions during construction and waste emplacement operations...

10 CFR 63.131 - General requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA... conditions encountered and changes in those conditions during construction and waste emplacement operations...

10 CFR 63.131 - General requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... in situ monitoring, laboratory and field testing, and in situ experiments, as may be appropriate to... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA... conditions encountered and changes in those conditions during construction and waste emplacement operations...

10 CFR 60.32 - Conditions of construction authorization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Conditions of construction authorization. 60.32 Section 60.32 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.32 Conditions of construction authorization...

10 CFR 60.33 - Amendment of construction authorization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Amendment of construction authorization. 60.33 Section 60.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.33 Amendment of construction authorization...

10 CFR 60.33 - Amendment of construction authorization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Amendment of construction authorization. 60.33 Section 60.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.33 Amendment of construction authorization...

10 CFR 60.32 - Conditions of construction authorization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Conditions of construction authorization. 60.32 Section 60.32 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.32 Conditions of construction authorization...

10 CFR 63.31 - Construction authorization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Construction authorization. 63.31 Section 63.31 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.31 Construction authorization...

10 CFR 60.32 - Conditions of construction authorization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Conditions of construction authorization. 60.32 Section 60.32 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.32 Conditions of construction authorization...

10 CFR 60.32 - Conditions of construction authorization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Conditions of construction authorization. 60.32 Section 60.32 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.32 Conditions of construction authorization...

10 CFR 60.33 - Amendment of construction authorization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Amendment of construction authorization. 60.33 Section 60.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.33 Amendment of construction authorization...

10 CFR 63.31 - Construction authorization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Construction authorization. 63.31 Section 63.31 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.31 Construction authorization...

10 CFR 63.31 - Construction authorization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Construction authorization. 63.31 Section 63.31 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.31 Construction authorization...

10 CFR 60.33 - Amendment of construction authorization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Amendment of construction authorization. 60.33 Section 60.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.33 Amendment of construction authorization...

Sunrise coal, an innovative New Indiana player continues to grow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buchsbaum, L.

2009-07-15

Sunrise Coal LLC's Carliste (Indiana) underground mine began development in 2006. Today, the room and pillar operation has grown to a 3 million tpy four unit continuous miner mine. Its coal has low (0.06%) chlorine level and is now being purchased to blend down high chlorine in Illinois Basin coal. The article describes the mining operation and equipment traces the growth of the company, founded in the 1970s by Row and Steve Laswell, emphasizing its focus on employee safety. 5 photos.

Effect of Environmental Enrichment on Aggression in BALB/cJ and BALB/cByJ Mice Monitored by Using an Automated System.

PubMed

Giles, Jareca M; Whitaker, Julia W; Moy, Sheryl S; Fletcher, Craig A

2018-04-18

Aggression among mice remains a common undesirable problem in laboratory settings, and animal welfare and scientific outcomes may become compromised depending on the severity of aggression. This study evaluated the effect of cage enrichment comprising a bilevel, mounted 'mezzanine' compared with a cotton square or shelter on intracage male aggression over a 6-wk period. Our first study involved home-cage behavioral challenges to male mice from a high aggression substrain (BALB/cJ) and low-aggression substrain (BALB/cByJ). Aggressive interactions and locomotor activity were scored manually and then compared with measures of activity obtained by using a continuous automated home-cagemonitoring system, the Digital Ventilated Caging (DVC) system. BALB/cJ mice exhibited similar levels of aggression acrosshousing conditions, whereas BALB/cByJ mice had lower aggression when housed with a mezzanine. In the second study,videorecordings and continuous DVC automated measures were collected over 24 h and divided into 12-h light and dark phases. BALB/cByJ mice-but not BALB/cJ-mice had increased aggressive behaviors during the dark phase. However, the DVC detected higher activity levels during the dark phase, compared with the light phase, in both substrains. Elevated activity levels recorded by the DVC correlated with fighting bouts and high levels of locomotion. These results show that a bilevel structural form of enrichment reduces aggression, depending on the BALB/c substrain, and confirms higher aggression levels in the BALB/cJ substrain. In addition, our findings provide evidence that the DVC is effective in identifying mouse cages with patterns of high activity levels, signaling possible aggression incidences, thus potentially allowing for early intervention and consequently improving animal welfare.

Examining solutions to missing data in longitudinal nursing research.

PubMed

Roberts, Mary B; Sullivan, Mary C; Winchester, Suzy B

2017-04-01

Longitudinal studies are highly valuable in pediatrics because they provide useful data about developmental patterns of child health and behavior over time. When data are missing, the value of the research is impacted. The study's purpose was to (1) introduce a three-step approach to assess and address missing data and (2) illustrate this approach using categorical and continuous-level variables from a longitudinal study of premature infants. A three-step approach with simulations was followed to assess the amount and pattern of missing data and to determine the most appropriate imputation method for the missing data. Patterns of missingness were Missing Completely at Random, Missing at Random, and Not Missing at Random. Missing continuous-level data were imputed using mean replacement, stochastic regression, multiple imputation, and fully conditional specification (FCS). Missing categorical-level data were imputed using last value carried forward, hot-decking, stochastic regression, and FCS. Simulations were used to evaluate these imputation methods under different patterns of missingness at different levels of missing data. The rate of missingness was 16-23% for continuous variables and 1-28% for categorical variables. FCS imputation provided the least difference in mean and standard deviation estimates for continuous measures. FCS imputation was acceptable for categorical measures. Results obtained through simulation reinforced and confirmed these findings. Significant investments are made in the collection of longitudinal data. The prudent handling of missing data can protect these investments and potentially improve the scientific information contained in pediatric longitudinal studies. © 2017 Wiley Periodicals, Inc.

HIGH LEVEL OF PERSISTENCE OF PEDIATRIC BIPOLAR-I DISORDER FROM CHILDHOOD ONTO ADOLESCENT YEARS: A FOUR YEAR PROSPECTIVE LONGITUDINAL FOLLOW-UP STUDY

PubMed Central

Wozniak, Janet; Petty, Carter R.; Schreck, Meghan; Moses, Alana; Faraone, Stephen V.; Biederman, Joseph

2011-01-01

Objective To examine the longitudinal course of pediatric bipolar (BP)-I disorder in youth transitioning from childhood into adolescence. Methods We conducted a four-year prospective follow-up study of 78 youth with BP-I disorder 6-17 years old at ascertainment followed up into adolescent years (13.4±3.9 years). All subjects were comprehensively assessed with structured diagnostic interviews, neuropsychological testing, psychosocial, educational and treatment history assessments. BP disorder was considered persistent if subjects met full criteria for DSM-IV BP-I disorder at follow-up. Results Of 78 BP-I participating youth subjects, 57 (73.1%), continued to meet full diagnostic criteria for BP-I Disorder. Of those with a non-persistent course, only 6.4% (n=5) were euthymic (i.e., syndromatic and symptomatic remission) at the 4-year follow-up and were not receiving pharmacotherapy for the disorder. The other non-persistent cases either continued to have subthreshold BP-I disorder (n=5, 6.4%), met full (n=3, 3.8%) or subthreshold (n=1, 1.3%) criteria for major depression, or were euthymic but were treated for the disorder (n=7, 9.0%). Full persistence was associated with higher rates of major depression and disruptive behavior disorders at the follow-up assessment and higher use of stimulant medicines at the baseline assessment. Non-Peristent BP-I was also characterized by high levels of dysfunction and morbidity. Conclusions This four-year follow-up shows that the majority of BP-I disorder youth continue to experience persistent disorder into their mid and late adolescent years and its persistence is associated with high levels of morbidity and disability. Persistence of subsyndromal forms of bipolar disorder was also associated with dysfunction and morbidity. PMID:21683960

A high-level object-oriented model for representing relationships in an electronic medical record.

PubMed Central

Dolin, R. H.

1994-01-01

The importance of electronic medical records to improve the quality and cost-effectiveness of medical care continues to be realized. This growing importance has spawned efforts at defining the structure and content of medical data, which is heterogeneous, highly inter-related, and complex. Computer-assisted data modeling tools have greatly facilitated the process of representing medical data, however the complex inter-relationships of medical information can result in data models that are large and cumbersome to manipulate and view. This report presents a high-level object-oriented model for representing the relationships between objects or entities that might exist in an electronic medical record. By defining the relationship between objects at a high level and providing for inheritance, this model enables relating any medical entity to any other medical entity, even though the relationships were not directly specified or known during data model design. PMID:7949981

Environmental Health: High-level Strategy and Leadership Needed to Continue Progress toward Protecting Children from Environmental Threats. Report to Congressional Requesters. GAO-10-205

ERIC Educational Resources Information Center

Stephenson, John B.

2010-01-01

Exposure to toxic chemicals or environmental pollutants may harm the health of the nation's 74 million children and contribute to increases in asthma and developmental impairments. In 2007, 66 percent of children lived in counties exceeding allowable levels for at least one of the six principal air pollutants that cause or aggravate asthma,…

Reconceptualizing Student Motivation in Physical Education: An Examination of What Resources Are Valued by Pre-Adolescent Girls in Contemporary Society

ERIC Educational Resources Information Center

O'Donovan, Toni; Kirk, David

2008-01-01

Despite receiving an unprecedented level of government funding to ensure young people have two hours of high quality physical education (PE) and sport, physical educators in the UK continue to decry poor motivation levels and disengaged youth in PE. The major purpose of this paper is to achieve a greater understanding of the factors that motivate…

High-Speed, Low-Level Flight: Aircrew Factors

DTIC Science & Technology

1980-03-01

relation to terrain information, threat detection and aircraft information, and highlighted many areas requiring further research. These include what...on a digital computer and used to produce , in real time, a continuous ’turbulence’ record for aircraft handling qualities studies in a piloted ground...Master Caution Unit" which produces a multitude of signals at varying tone levels, causing pilots to ironically call it "The Airbus Symphony". The

A case of sleep apnea syndrome manifesting severe hypertension with high plasma norepinephrine levels.

PubMed

Makino, Shinya; Iwata, Masanobu; Fujiwara, Masayoshi; Ike, Shinpei; Tateyama, Hitone

2006-06-01

A 55-year-old female was admitted to our hospital with severe hypertension (274/140 mmHg). Endocrinological examination revealed that her plasma levels of norepinephrine (NE) was elevated with high levels of urinary NE, normetanephrine and vanillylmandelic acid (VMA), suggesting the presence of pheochromocytoma. However, neither computed tomography nor MIBG scintigraphy detected any catecholamine-producing tumor in or outside the adrenal glands. She was screened with full polysomnography because of heavy snoring, and the diagnosis of severe obstructive sleep apnea syndrome (OSAS) was made. She was treated with calcium channel blocker for three weeks, but severe hypertension persisted. After treatment with nasal continuous positive airway pressure (CPAP) was added, her blood pressure gradually lowered week by week. Concomitantly, the levels of plasma and urinary NE, urinary normetanephrine and urinary VMA were normalized following nasal CPAP therapy for 2 weeks. Additional treatments with alpha-adrenergic blocker further decreased her home blood pressure. After a year, she continued nasal CPAP therapy and her blood pressure was nearly below 160/100 mmHg. Urinary NE level was slightly above normal range and other catecholamines stayed within the normal range. This case shows that patients with OSAS could develop severe hypertension through elevated sympathetic tone, mimicking pheochromocytoma. Nasal CPAP therapy is recommended not only to improve hypertension and catecholamine excess but also to distinguish the condition from pheochromocytoma.

Maintaining routine despite ongoing exposure to terrorism: a healthy strategy for adolescents?

PubMed

Pat-Horenczyk, Ruth; Schiff, Miriam; Doppelt, Osnat

2006-08-01

To examine the association between ongoing terrorism and Israeli adolescents' routine activities. A total of 1336 junior high and high school students from Jerusalem (46.9% boys and 53.1% girls) self-reported on measures of maintaining or reducing their level of routine activities, perceived parental monitoring, posttraumatic symptoms (PTS) and functional impairment. We used linear regressions to explore possible associations between decreasing (or maintaining) level of routine activities, parental monitoring, and PTS and functional impairment. A majority of the adolescents reported that under the recurrent threat of terrorism they maintained their routine (i.e., 65.8% continued using public transportation). Similarly, more than half the students perceived their parents as encouraging them to maintain their routine activities. Furthermore, greater exposure to terrorism was associated with more PTS symptoms and functional impairment. Nonetheless, a reduced level of routine activities was a significant predictor for higher PTS and functional impairment, even after controlling for level of exposure to terrorism, gender and age. Similarly, perceived parental limiting of routine activities was a significant predictor for higher PTS and functional impairment, even after controlling for gender, age and the level of exposure to terrorism. Our results support practitioners' recommendations to encourage continuity in daily routine. Disruption of routine activities may result in the development of avoidance reactions that can lead to posttraumatic stress disorder.

Method for determining molten metal pool level in twin-belt continuous casting machines

DOEpatents

Kaiser, Timothy D.; Daniel, Sabah S.; Dykes, Charles D.

1989-03-21

A method for determining level of molten metal in the input of a continuous metal casting machine having at least one endless, flexible, revolving casting belt with a surface which engages the molten metal to be cast and a reverse, cooled surface along which is directed high velocity liquid coolant includes the steps of predetermining the desired range of positions of the molten metal pool and positioning at least seven heat-sensing transducers in bearing contact with the moving reverse belt surface and spaced in upstream-downstream relationship relative to belt travel spanning the desired pool levels. A predetermined temperature threshold is set, somewhat above coolant temperature and the output signals of the transducer sensors are scanned regarding their output signals indicative of temperatures of the moving reverse belt surface. Position of the molten pool is determined using temperature interpolation between any successive pair of upstream-downstream spaced sensors, which follows confirmation that two succeeding downstream sensors are at temperature levels exceeding threshold temperature. The method accordingly provides high resolution for determining pool position, and verifies the determined position by utilizing full-strength signals from two succeeding downstream sensors. In addition, dual sensors are used at each position spanning the desired range of molten metal pool levels to provide redundancy, wherein only the higher temperature of each pair of sensors at a station is utilized.

Work Stress and Metabolic Syndrome in Police Officers. A Prospective Study

PubMed Central

Garbarino, Sergio; Magnavita, Nicola

2015-01-01

Objective The aim of this longitudinal study was to evaluate the association between occupational stress and metabolic syndrome (MetS) in a rapid response police unit. Method Work-related stress was continuously monitored during the 5-year period with both the Demand-Control-Support (DCS) and the Effort-Reward Imbalance (ERI) models. Blood pressure, body mass index (BMI), waist circumference, triglycerides, HDL-cholesterol, and fasting blood glucose were measured at baseline in January 2009, and in January 2014. 234 out of 290 police officers (81%) completed the follow-up. Results The majority of police officers had high stress levels. At follow-up, police officers in the highest quartile of stress had significantly higher mean levels of triglycerides, and lower levels of HDL-cholesterol than their colleagues in the lowest quartile. Police officers with high stress had an increased adjusted risk of developing MetS (aOR = 2.68; CI95% = 1.08–6.70), and hypertriglyceridemia (aOR = 7.86; CI95 = 1.29–48.04). Demand and Effort were significant predictors of MetS. Conclusion Our study supports the hypothesis that work-related stress induces MetS, particularly through its effects on blood lipids. Future longitudinal studies with continuous monitoring of stress levels will definitively confirm this hypothesis. PMID:26641879

Improving the satellite communication efficiency of the accumulative acknowledgement strategies

NASA Astrophysics Data System (ADS)

Duarte, Otto Carlos M. B.; de Lima, Heliomar Medeiros

The performances of two finite buffer error recovery strategies are analyzed. In both strategies the retransmission request decision between selective repeat and continuous retransmission is based on an imminent buffer overflow condition. These are accumulative acknowledgment schemes, but in the second strategy the selective-repeat control frame is uniquely an individual negative acknowledgment. The two strategies take advantage of the availability of a greater buffer capacity, making the most of the selective repeat, postponing the sending of a continuous retransmission request. Numerical results show a better performance very close to the ideal, but it does not integrally conform to the high-level data link control (HDLC) procedures. It is shown that these strategies are well suited for high-speed data transfer in the high-error-rate satellite environment.

A national project to evaluate and reduce high sound pressure levels from music.

PubMed

Ryberg, Johanna Bengtsson

2009-01-01

The highest recommended sound pressure levels for leisure sounds (music) in Sweden are 100 dB LAeq and 115 dB LAFmax for adults, and 97 dB LAeq and 110 dB LAFmax where children under the age of 13 have access. For arrangements intended for children, levels should be consistently less than 90 dB LAeq. In 2005, a national project was carried out with the aim of improving environments with high sound pressure levels from music, such as concert halls, restaurants, and cinemas. The project covered both live and recorded music. Of Sweden's 290 municipalities, 134 took part in the project, and 93 of these carried out sound measurements. Four hundred and seventy one establishments were investigated, 24% of which exceeded the highest recommended sound pressure levels for leisure sounds in Sweden. Of festival and concert events, 42% exceeded the recommended levels. Those who visit music events/establishments thus run a relatively high risk of exposure to harmful sound levels. Continued supervision in this field is therefore crucial.

Developmental Expression of Violaxanthin De-Epoxidase in Leaves of Tobacco Growing under High and Low Light1

PubMed Central

Bugos, Robert C.; Chang, Sue-Hwei; Yamamoto, Harry Y.

1999-01-01

Violaxanthin de-epoxidase (VDE) is a lumen-localized enzyme that catalyzes the de-epoxidation of violaxanthin in the thylakoid membrane upon formation of a transthylakoid pH gradient. We investigated the developmental expression of VDE in leaves of mature tobacco (Nicotiana tabacum) plants grown under high-light conditions (in the field) and low-light conditions (in a growth chamber). The difference in light conditions was evident by the increased pool size (violaxanthin + antheraxanthin + zeaxanthin, VAZ) throughout leaf development in field-grown plants. VDE activity based on chlorophyll or leaf area was low in the youngest leaves, with the levels increasing with increasing leaf age in both high- and low-light-grown plants. However, in high-light-grown plants, the younger leaves in early leaf expansion showed a more rapid increase in VDE activity and maintained higher levels of VDE transcript in more leaves, indicating that high light may induce greater levels of VDE. VDE transcript levels decreased substantially in leaves of mid-leaf expansion, while the levels of enzyme continued to increase, suggesting that the VDE enzyme does not turn over rapidly. The level of VDE changed in an inverse, nonlinear relationship with respect to the VAZ pool, suggesting that enzyme levels could be indirectly regulated by the VAZ pool. PMID:10482676

Developmental expression of violaxanthin de-epoxidase in leaves of tobacco growing under high and low light.

PubMed

Bugos, R C; Chang, S H; Yamamoto, H Y

1999-09-01

Violaxanthin de-epoxidase (VDE) is a lumen-localized enzyme that catalyzes the de-epoxidation of violaxanthin in the thylakoid membrane upon formation of a transthylakoid pH gradient. We investigated the developmental expression of VDE in leaves of mature tobacco (Nicotiana tabacum) plants grown under high-light conditions (in the field) and low-light conditions (in a growth chamber). The difference in light conditions was evident by the increased pool size (violaxanthin + antheraxanthin + zeaxanthin, VAZ) throughout leaf development in field-grown plants. VDE activity based on chlorophyll or leaf area was low in the youngest leaves, with the levels increasing with increasing leaf age in both high- and low-light-grown plants. However, in high-light-grown plants, the younger leaves in early leaf expansion showed a more rapid increase in VDE activity and maintained higher levels of VDE transcript in more leaves, indicating that high light may induce greater levels of VDE. VDE transcript levels decreased substantially in leaves of mid-leaf expansion, while the levels of enzyme continued to increase, suggesting that the VDE enzyme does not turn over rapidly. The level of VDE changed in an inverse, nonlinear relationship with respect to the VAZ pool, suggesting that enzyme levels could be indirectly regulated by the VAZ pool.

Benchmark concentrations for methyl mercury obtained from the 9-year follow-up of the Seychelles Child Development Study.

PubMed

van Wijngaarden, Edwin; Beck, Christopher; Shamlaye, Conrad F; Cernichiari, Elsa; Davidson, Philip W; Myers, Gary J; Clarkson, Thomas W

2006-09-01

Methyl mercury (MeHg) is highly toxic to the developing nervous system. Human exposure is mainly from fish consumption since small amounts are present in all fish. Findings of developmental neurotoxicity following high-level prenatal exposure to MeHg raised the question of whether children whose mothers consumed fish contaminated with background levels during pregnancy are at an increased risk of impaired neurological function. Benchmark doses determined from studies in New Zealand, and the Faroese and Seychelles Islands indicate that a level of 4-25 parts per million (ppm) measured in maternal hair may carry a risk to the infant. However, there are numerous sources of uncertainty that could affect the derivation of benchmark doses, and it is crucial to continue to investigate the most appropriate derivation of safe consumption levels. Earlier, we published the findings from benchmark analyses applied to the data collected on the Seychelles main cohort at the 66-month follow-up period. Here, we expand on the main cohort analyses by determining the benchmark doses (BMD) of MeHg level in maternal hair based on 643 Seychellois children for whom 26 different neurobehavioral endpoints were measured at 9 years of age. Dose-response models applied to these continuous endpoints incorporated a variety of covariates and included the k-power model, the Weibull model, and the logistic model. The average 95% lower confidence limit of the BMD (BMDL) across all 26 endpoints varied from 20.1 ppm (range=17.2-22.5) for the logistic model to 20.4 ppm (range=17.9-23.0) for the k-power model. These estimates are somewhat lower than those obtained after 66 months of follow-up. The Seychelles Child Development Study continues to provide a firm scientific basis for the derivation of safe levels of MeHg consumption.

The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study

PubMed Central

Buscot, Marie-jeanne; Magnussen, Costan G.; Juonala, Markus; Pitkänen, Niina; Lehtimäki, Terho; Viikari, Jorma S. A.; Kähönen, Mika; Hutri-Kähönen, Nina; Schork, Nicholas J.

2016-01-01

Low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) are modifiable risk factors for cardiovascular disease. Several genetic loci for predisposition to abnormal LDL-C, HDL-C and TG have been identified. However, it remains unclear whether these loci are consistently associated with serum lipid levels at each age or with unique developmental trajectories. Therefore, we assessed the association between genome wide association studies (GWAS) derived polygenic genetic risk scores and LDL-C, HDL-C, and triglyceride trajectories from childhood to adulthood using data available from the 27-year European ‘Cardiovascular Risk in Young Finns’ Study. For 2,442 participants, three weighted genetic risk scores (wGRSs) for HDL-C (38 SNPs), LDL-C (14 SNPs) and triglycerides (24 SNPs) were computed and tested for association with serum lipoprotein levels measured up to 8 times between 1980 and 2011. The categorical analyses revealed no clear divergence of blood lipid trajectories over time between wGRSs categories, with participants in the lower wGRS quartiles tending to have average lipoprotein concentrations 30 to 45% lower than those in the upper-quartile wGRS beginning at age 3 years and continuing through to age 49 years (where the upper-quartile wGRS have 4–7 more risk alleles than the lower wGRS group). Continuous analyses, however, revealed a significant but moderate time-dependent genetic interaction for HDL-C levels, with the association between HDL-C and the continuous HDL-C risk score weakening slightly with age. Conversely, in males, the association between the continuous TG genetic risk score and triglycerides levels tended to be lower in childhood and become more pronounced after the age of 25 years. Although the influence of genetic factors on age-specific lipoprotein values and developmental trajectories is complex, our data show that wGRSs are highly predictive of HDL-C, LDL-C, and triglyceride levels at all ages. PMID:26731281

Continuous delivery of ropinirole reverses motor deficits without dyskinesia induction in MPTP-treated common marmosets.

PubMed

Stockwell, K A; Virley, D J; Perren, M; Iravani, M M; Jackson, M J; Rose, S; Jenner, P

2008-05-01

L-DOPA treatment of Parkinson's disease induces a high incidence of motor complications, notably dyskinesia. Longer acting dopamine agonists, e.g. ropinirole, are thought to produce more continuous dopaminergic stimulation and less severe dyskinesia. However, standard oral administration of dopamine agonists does not result in constant plasma drug levels, therefore, more continuous drug delivery may result in both prolonged reversal of motor deficits and reduced levels of dyskinesia. Therefore, we compared the effects of repeated oral administration of ropinirole to constant subcutaneous infusion in MPTP-treated common marmosets. Animals received oral administration (0.4 mg/kg, BID) or continuous infusion of ropinirole (0.8 mg/kg/day) via osmotic minipumps for 14 days (Phase I). The treatments were then switched and continued for a further 14 days (Phase II). In Phase I, locomotor activity was similar between treatment groups but reversal of motor disability was more pronounced in animals receiving continuous infusion. Dyskinesia intensity was low in both groups however there was a trend suggestive of less marked dyskinesia in those animals receiving continuous infusion. In Phase II, increased locomotor activity was maintained but animals switched from oral to continuous treatment showing an initial period of enhanced locomotor activity. The reversal of motor disability was maintained in both groups, however, motor disability tended towards greater improvement following continuous infusion. Importantly, dyskinesia remained low in both groups suggesting that constant delivery of ropinirole neither leads to priming nor expression of dyskinesia. These results suggest that a once-daily controlled-release formulation may provide improvements over existing benefits with standard oral ropinirole in Parkinson's disease patients.

Determining Sea-Level Rise and Coastal Subsidence in the Canadian Arctic Using a Dense GPS Velocity Field for North America

NASA Astrophysics Data System (ADS)

Craymer, M.; Forbes, D.; Henton, J.; Lapelle, E.; Piraszewski, M.; Solomon, S.

2005-12-01

With observed climate warming in the western Canadian Arctic and potential increases in regional sea level, we anticipate expansion of the coastal region subject to rising relative sea level and increased flooding risk. This is a concern for coastal communities such as Tuktoyaktuk and Sachs Harbour and for the design and safety of hydrocarbon production facilities on the Mackenzie Delta. To provide a framework in which to monitor these changes, a consistent velocity field has been determined from GPS observations throughout North America, including the Canadian Arctic Archipelago and the Mackenzie Delta region. An expanded network of continuous GPS sites and multi-epoch (episodic) sites has enabled an increased density that enhances the application to geophysical studies including the discrimination of crustal motion, other components of coastal subsidence, and sea-level rise. To obtain a dense velocity field consistent at all scales, we have combined weekly solutions of continuous GPS sites from different agencies in Canada and the USA, together with the global reference frame under the North American Reference Frame initiative. Although there is already a high density of continuous GPS sites in the conterminous United States, there are many fewer such sites in Canada. To make up for this lack of density, we have incorporated high-accuracy episodic GPS observations on stable monuments distributed throughout Canada. By combining up to ten years of repeated, episodic GPS observations at such sites, together with weekly solutions from the continuous sites, we have obtained a highly consistent velocity field with a significantly increased spatial sampling of crustal deformation throughout Canada. This exhibits a spatially coherent pattern of uplift and subsidence in Canada that is consistent with the expected rates of glacial isostatic adjustment. To determine the contribution of vertical motion to sea-level rise under climate warming in the Canadian Arctic, we have established co-located tide gauges and continuous GPS at a number of sites across the Canadian Arctic, including Tuktoyaktuk on the eastern side of the Mackenzie Delta. We are also investigating additional sources of subsidence in the delta, including sediment loading, compaction of unfrozen and discontinuously ice-bonded sediments, and anticipated subsidence resulting from future natural gas production. Further densification of the velocity field, including the addition of new sites in the delta, and regular reoccupation of episodic sites will assist in determining local rates of motion. Strategies for discriminating the various components of subsidence in this large delta include episodic GPS on monuments and borehole casing penetrating to various depths and supporting InSAR analysis and geological data. Coastal flooding hazards will be evaluated using digital elevation models derived from real-time kinematic GPS, airborne LiDAR surveys, and synthetic aperture radar flood mapping.

Abuse Tolerance Improvements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orendorff, Christopher J.; Nagasubramanian, Ganesan; Fenton, Kyle R.

As lithium-ion battery technologies mature, the size and energy of these systems continues to increase (> 50 kWh for EVs); making safety and reliability of these high energy systems increasingly important. While most material advances for lithium-ion chemistries are directed toward improving cell performance (capacity, energy, cycle life, etc.), there are a variety of materials advancements that can be made to improve lithium-ion battery safety. Issues including energetic thermal runaway, electrolyte decomposition and flammability, anode SEI stability, and cell-level abuse tolerance continue to be critical safety concerns. This report highlights work with our collaborators to develop advanced materials to improvemore » lithium-ion battery safety and abuse tolerance and to perform cell-level characterization of new materials.« less

Continuous low- to moderate-intensity exercise training is as effective as moderate- to high-intensity exercise training at lowering blood HbA(1c) in obese type 2 diabetes patients.

PubMed

Hansen, D; Dendale, P; Jonkers, R A M; Beelen, M; Manders, R J F; Corluy, L; Mullens, A; Berger, J; Meeusen, R; van Loon, L J C

2009-09-01

Exercise represents an effective interventional strategy to improve glycaemic control in type 2 diabetes patients. However, the impact of exercise intensity on the benefits of exercise training remains to be established. In the present study, we compared the clinical benefits of 6 months of continuous low- to moderate-intensity exercise training with those of continuous moderate- to high-intensity exercise training, matched for energy expenditure, in obese type 2 diabetes patients. Fifty male obese type 2 diabetes patients (age 59 +/- 8 years, BMI 32 +/- 4 kg/m(2)) participated in a 6 month continuous endurance-type exercise training programme. All participants performed three supervised exercise sessions per week, either 55 min at 50% of whole body peak oxygen uptake (VO(2)peak (low to moderate intensity) or 40 min at 75% of VO(2)peak (moderate to high intensity). Oral glucose tolerance, blood glycated haemoglobin, lipid profile, body composition, maximal workload capacity, whole body and skeletal muscle oxidative capacity and skeletal muscle fibre type composition were assessed before and after 2 and 6 months of intervention. The entire 6 month intervention programme was completed by 37 participants. Continuous endurance-type exercise training reduced blood glycated haemoglobin levels, LDL-cholesterol concentrations, body weight and leg fat mass, and increased VO(2)peak, lean muscle mass and skeletal muscle cytochrome c oxidase and citrate synthase activity (p < 0.05). No differences were observed between the groups training at low to moderate or moderate to high intensity. When matched for energy cost, prolonged continuous low- to moderate-intensity endurance-type exercise training is equally effective as continuous moderate- to high-intensity training in lowering blood glycated haemoglobin and increasing whole body and skeletal muscle oxidative capacity in obese type 2 diabetes patients. ISRCTN32206301 None.

Terahertz cascades from nanoparticles

NASA Astrophysics Data System (ADS)

Arnardottir, K. B.; Liew, T. C. H.

2018-05-01

In this article we propose a system capable of terahertz (THz) radiation with quantum yield above unity. The system consists of nanoparticles where the material composition varies along the radial direction of each nanoparticle in such a way that a ladder of equidistant energy levels emerges. By then exciting the highest level of this ladder we produce multiple photons of the same frequency in the THz range. We demonstrate how we can calculate a continuous material composition profile that achieves a high quantum yield and then show that a more experimentally friendly design of a multishell nanoparticle can still result in a high quantum yield.

Tank 19F Folding Crawler Final Evaluation, Rev. 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nance, T.

2000-10-25

The Department of Energy (DOE) is committed to removing millions of gallons of high-level radioactive waste from 51 underground waste storage tanks at the Savannah River Site (SRS). The primary radioactive waste constituents are strontium, plutonium,and cesium. It is recognized that the continued storage of this waste is a risk to the public, workers, and the environment. SRS was the first site in the DOE complex to have emptied and operationally closed a high-level radioactive waste tank. The task of emptying and closing the rest of the tanks will be completed by FY28.

10 CFR 72.18 - Elimination of repetition.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Elimination of repetition. 72.18 Section 72.18 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE License...

10 CFR 72.13 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Applicability. 72.13 Section 72.13 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.13...

10 CFR 72.5 - Interpretations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Interpretations. 72.5 Section 72.5 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.5...

10 CFR 72.5 - Interpretations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Interpretations. 72.5 Section 72.5 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.5...

10 CFR 60.73 - Reports of deficiencies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Reports of deficiencies. 60.73 Section 60.73 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Records, Reports, Tests, and Inspections § 60.73 Reports of deficiencies. DOE shall promptly...

10 CFR 60.23 - Elimination of repetition.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Elimination of repetition. 60.23 Section 60.23 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses License Applications § 60.23 Elimination of repetition. In its application, environmental...

77 FR 3393 - Atlantic Highly Migratory Species; 2012 Atlantic Shark Commercial Fishing Season

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-24

... for the public to decipher, as the wording is not clear and/or the math seems not to be accurate. NMFS... stated that if ``overharvest continues to occur and the level reaches 60 percent or more of the 2012 base...

10 CFR 72.18 - Elimination of repetition.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Elimination of repetition. 72.18 Section 72.18 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE License...

10 CFR 72.13 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Applicability. 72.13 Section 72.13 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.13...

10 CFR 72.28 - Contents of application: Applicant's technical qualifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Contents of application: Applicant's technical qualifications. 72.28 Section 72.28 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED...

10 CFR 72.34 - Environmental report.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Environmental report. 72.34 Section 72.34 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE License Application, Form...

10 CFR 72.90 - General considerations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false General considerations. 72.90 Section 72.90 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Siting Evaluation Factors...

10 CFR 60.46 - Particular activities requiring license amendment.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Particular activities requiring license amendment. 60.46 Section 60.46 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses License Issuance and Amendment § 60.46 Particular activities...

10 CFR 63.322 - Human intrusion scenario.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Human intrusion scenario. 63.322 Section 63.322 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Human Intrusion...

10 CFR 63.322 - Human intrusion scenario.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Human intrusion scenario. 63.322 Section 63.322 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Human Intrusion...

10 CFR 63.322 - Human intrusion scenario.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Human intrusion scenario. 63.322 Section 63.322 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Human Intrusion...

10 CFR 63.322 - Human intrusion scenario.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Human intrusion scenario. 63.322 Section 63.322 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Human Intrusion...

Standards Supporters Firing Back

ERIC Educational Resources Information Center

Ujifusa, Andrew

2013-01-01

Supporters of the Common Core State Standards are moving to confront increasingly high-profile opposition to the standards at the state and national levels by rallying the private sector and initiating coordinated public relations and advertising campaigns as schools continue implementation. In states such as Michigan and Tennessee, where…

10 CFR 60.4 - Communications and records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Communications and records. 60.4 Section 60.4 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.4 Communications and records. (a) Except where otherwise specified, all...

10 CFR 60.4 - Communications and records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Communications and records. 60.4 Section 60.4 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.4 Communications and records. (a) Except where otherwise specified, all...

10 CFR 60.4 - Communications and records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Communications and records. 60.4 Section 60.4 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.4 Communications and records. (a) Except where otherwise specified, all...

10 CFR 60.3 - License required.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General... byproduct material at a geologic repository operations area except as authorized by a license issued by the Commission pursuant to this part. (b) DOE shall not commence construction of a geologic repository operations...

10 CFR 60.8 - Information collection requirements: Approval.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Information collection requirements: Approval. 60.8 Section 60.8 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.8 Information collection requirements: Approval. (a) The...

10 CFR 60.46 - Particular activities requiring license amendment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Particular activities requiring license amendment. 60.46 Section 60.46 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses License Issuance and Amendment § 60.46 Particular activities...

10 CFR 63.143 - Implementation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Implementation. 63.143 Section 63.143 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Quality Assurance § 63.143 Implementation. DOE shall implement a quality assurance program...

The Trail of Tears Continues: Dispossession and Genocide of the Native American Indians.

ERIC Educational Resources Information Center

Bender, Albert M.

1981-01-01

Describes the high cultural level of native American Indian populations at the time of conquest. Illustrates how cultural breakdown and demographic decimation have resulted from systematic policies that focused on exploiting natural resources at the expense of native peoples. (GC)

Unappreciated epidemiology: the churn effect in a regional HIV care programme.

PubMed

Gill, M J; Krentz, H B

2009-08-01

High levels of geographic mobility in and out of HIV care centres (i.e. the churn effect) can disrupt the continuity of patient care, misalign prevention services, impact local prevalence data perturbing optimal allocation of resources, and contribute to logical challenges in repeated transfer of health records. We report on the clinical, demographic, and administrative impact of high population turnover within HIV populations.

Generalised summation-by-parts operators and variable coefficients

NASA Astrophysics Data System (ADS)

Ranocha, Hendrik

2018-06-01

High-order methods for conservation laws can be highly efficient if their stability is ensured. A suitable means mimicking estimates of the continuous level is provided by summation-by-parts (SBP) operators and the weak enforcement of boundary conditions. Recently, there has been an increasing interest in generalised SBP operators both in the finite difference and the discontinuous Galerkin spectral element framework. However, if generalised SBP operators are used, the treatment of the boundaries becomes more difficult since some properties of the continuous level are no longer mimicked discretely - interpolating the product of two functions will in general result in a value different from the product of the interpolations. Thus, desired properties such as conservation and stability are more difficult to obtain. Here, new formulations are proposed, allowing the creation of discretisations using general SBP operators that are both conservative and stable. Thus, several shortcomings that might be attributed to generalised SBP operators are overcome (cf. Nordström and Ruggiu (2017) [38] and Manzanero et al. (2017) [39]).

Control over high peak-power laser light and laser-driven X-rays

NASA Astrophysics Data System (ADS)

Zhao, Baozhen; Banerjee, Sudeep; Yan, Wenchao; Zhang, Ping; Zhang, Jun; Golovin, Grigory; Liu, Cheng; Fruhling, Colton; Haden, Daniel; Chen, Shouyuan; Umstadter, Donald

2018-04-01

An optical system was demonstrated that enables continuous control over the peak power level of ultrashort duration laser light. The optical characteristics of amplified and compressed femtosecond-duration light from a chirped-pulse amplification laser are shown to remain invariant and maintain high-fidelity using this system. When the peak power was varied by an order-of-magnitude, up to its maximum attainable value, the phase, spectral bandwidth, polarization state, and focusability of the light remained constant. This capability led to precise control of the focused laser intensity and enabled a correspondingly high level of control over the power of an all-laser-driven Thomson X-ray light source.

Application Specific Electronic Module Program (ASEM), Final Technical Report.

DTIC Science & Technology

1994-12-14

relatively high temperatures , may induce a metal break or other continuity problems. Secondly, the improved electrical environment at the module level vs...wafer probe can permit higher speed tests to be applied, isolating marginal die. Thirdly, high reliability screens, such as temperature cycling, bum-in...The high temperature aging is done at 150’ C for 500 hours. The thermal cycle treatments are from 0- 100 0 C and 3 cycles per hour are done. The

Latin America and the Caribbean: Issues for the 109th Congress

DTIC Science & Technology

2005-05-26

Dominican tax on drinks containing high fructose corn syrup , a major U.S. product, that had threatened the country’s chances of being included in the U.S...has complained about Mexico’s 20% tax on soft drinks made with high fructose corn syrup (HFCS), with devastating impact on HFCS sales. Under...unstable political environment. In Peru, President Alejandro Toledo remains extremely unpopular, but the economy has continued to grow at high levels

Taurine supplementation increases skeletal muscle force production and protects muscle function during and after high-frequency in vitro stimulation.

PubMed

Goodman, Craig A; Horvath, Deanna; Stathis, Christos; Mori, Trevor; Croft, Kevin; Murphy, Robyn M; Hayes, Alan

2009-07-01

Recent studies report that depletion and repletion of muscle taurine (Tau) to endogenous levels affects skeletal muscle contractility in vitro. In this study, muscle Tau content was raised above endogenous levels by supplementing male Sprague-Dawley rats with 2.5% (wt/vol) Tau in drinking water for 2 wk, after which extensor digitorum longus (EDL) muscles were examined for in vitro contractile properties, fatigue resistance, and recovery from fatigue after two different high-frequency stimulation bouts. Tau supplementation increased muscle Tau content by approximately 40% and isometric twitch force by 19%, shifted the force-frequency relationship upward and to the left, increased specific force by 4.2%, and increased muscle calsequestrin protein content by 49%. Force at the end of a 10-s (100 Hz) continuous tetanic stimulation was 6% greater than controls, while force at the end of the 3-min intermittent high-frequency stimulation bout was significantly higher than controls, with a 12% greater area under the force curve. For 1 h after the 10-s continuous stimulation, tetanic force in Tau-supplemented muscles remained relatively stable while control muscle force gradually deteriorated. After the 3-min intermittent bout, tetanic force continued to slowly recover over the next 1 h, while control muscle force again began to decline. Tau supplementation attenuated F(2)-isoprostane production (a sensitive indicator of reactive oxygen species-induced lipid peroxidation) during the 3-min intermittent stimulation bout. Finally, Tau transporter protein expression was not altered by the Tau supplementation. Our results demonstrate that raising Tau content above endogenous levels increases twitch and subtetanic and specific force in rat fast-twitch skeletal muscle. Also, we demonstrate that raising Tau protects muscle function during high-frequency in vitro stimulation and the ensuing recovery period and helps reduce oxidative stress during prolonged stimulation.

A VCSEL based system for on-site monitoring of low level methane emission

NASA Astrophysics Data System (ADS)

Kannath, A.; Hodgkinson, J.; Gillard, R. G.; Riley, R. J.; Tatam, R. P.

2011-03-01

Continuous monitoring of methane emissions has assumed greater significance in the recent past due to increasing focus on global warming issues. Many industries have also identified the need for ppm level methane measurement as a means of gaining carbon credits. Conventional instruments based on NDIR spectroscopy are unable to offer the high selectivity and sensitivity required for such measurements. Here we discuss the development of a robust VCSEL based system for accurate low level measurements of methane. A possible area of application is the measurement of residual methane whilst monitoring the output of flare stacks and exhaust gases from methane combustion engines. The system employs a Wavelength Modulation Spectroscopy (WMS) scheme with second harmonic detection at 1651 nm. Optimum modulation frequency and ramp rates were chosen to maintain high resolution and fast response times which are vital for the intended application. Advanced data processing techniques were used to achieve long term sensitivity of the order of 10-5 in absorbance. The system is immune to cross interference from other gases and its inherent design features makes it ideal for large scale commercial production. The instrument maintains its calibration and offers a completely automated continuous monitoring solution for remote on site deployment.

Progress in high-power continuous-wave quantum cascade lasers [Invited].

PubMed

Figueiredo, Pedro; Suttinger, Matthew; Go, Rowel; Tsvid, Eugene; Patel, C Kumar N; Lyakh, Arkadiy

2017-11-01

Multi-watt continuous-wave room temperature operation with efficiency exceeding 10% has been demonstrated for quantum cascade lasers essentially in the entire mid-wave and long-wave infrared spectral regions. Along with interband cascade lasers, these devices are the only room-temperature lasers that directly convert electrical power into mid- and long-infrared optical power. In this paper, we review the progress in high-power quantum cascade lasers made over the last 10 years. Specifically, an overview of the most important active region, waveguide, and thermal design techniques is presented, and various aspects of die packaging for high-power applications are discussed. Prospects of power scaling with lateral device dimensions for reaching optical power level in the range from 10 W to 20 W are also analyzed. Finally, coherent and spectral beam-combining techniques for very high-power infrared platforms are discussed.

The Role of Educational Aspirations and Expectations in the Discontinuity of Intergenerational Low-Income Status

PubMed Central

Lee, Jungeun Olivia; Hill,, Karl G.; Hawkins, J. David

2012-01-01

This study investigated one potential mechanism mediating continuity and discontinuity in low-income status across generations: children's educational aspirations and expectations. Data were drawn from a community sample of 808 participants who were followed from age 10 to 30. Four trajectory groups of children's educational aspirations and expectations were identified from ages 10 to 18 (grades five through 12): “stable-high” group, “stable-low” group, “increaser” group, and “decreaser” group. Among participants from low-income families, those in the stable-high group and the increaser group were equally likely to graduate from high school. High school graduation was positively associated with level of total household income at age 30. Findings suggest that social work efforts that support the development of high educational aspirations and expectations in children might serve to reduce the intergenerational continuity of low-income status. PMID:24385713

Reduction of radiation exposure while maintaining high-quality fluoroscopic images during interventional cardiology using novel x-ray tube technology with extra beam filtering.

PubMed

den Boer, A; de Feyter, P J; Hummel, W A; Keane, D; Roelandt, J R

1994-06-01

Radiographic technology plays an integral role in interventional cardiology. The number of interventions continues to increase, and the associated radiation exposure to patients and personnel is of major concern. This study was undertaken to determine whether a newly developed x-ray tube deploying grid-switched pulsed fluoroscopy and extra beam filtering can achieve a reduction in radiation exposure while maintaining fluoroscopic images of high quality. Three fluoroscopic techniques were compared: continuous fluoroscopy, pulsed fluoroscopy, and a newly developed high-output pulsed fluoroscopy with extra filtering. To ascertain differences in the quality of images and to determine differences in patient entrance and investigator radiation exposure, the radiated volume curve was measured to determine the required high voltage levels (kVpeak) for different object sizes for each fluoroscopic mode. The fluoroscopic data of 124 patient procedures were combined. The data were analyzed for radiographic projections, image intensifier field size, and x-ray tube kilovoltage levels (kVpeak). On the basis of this analysis, a reference procedure was constructed. The reference procedure was tested on a phantom or dummy patient by all three fluoroscopic modes. The phantom was so designed that the kilovoltage requirements for each projection were comparable to those needed for the average patient. Radiation exposure of the operator and patient was measured during each mode. The patient entrance dose was measured in air, and the operator dose was measured by 18 dosimeters on a dummy operator. Pulsed compared with continuous fluoroscopy could be performed with improved image quality at lower kilovoltages. The patient entrance dose was reduced by 21% and the operator dose by 54%. High-output pulsed fluoroscopy with extra beam filtering compared with continuous fluoroscopy improved the image quality, lowered the kilovoltage requirements, and reduced the patient entrance dose by 55% and the operator dose by 69%. High-output pulsed fluoroscopy with a grid-switched tube and extra filtering improves the image quality and significantly reduces both the operator dose and patient dose.

The 9th Grade Shock and the High School Dropout Crisis

PubMed Central

Pharris-Ciurej, Nikolas; Hirschman, Charles; Willhoft, Joseph

2011-01-01

Retrospective questions on educational attainment in national surveys and censuses tend to over-estimate high school graduation rates by 15 to 20 percentage points relative to administrative records. Administrative data on educational enrollment are, however, only available at the aggregate level (state, school district, and school levels) and the recording of inter-school transfers are generally incomplete. With access to linked individual-level administrative records from a very large “West Coast metropolitan school district” we track patterns of high school attrition and on-time high school graduation of individual students. Even with adjustments for the omission of out-of-district transfers (estimates of omission are presented), the results of this study show that failure in high school, as indexed by retention and attrition, are almost as common as on-time high school graduation. In addition to the usual risk factors of disadvantaged background, we find that the “9th grade shock”—an unpredicted decline in academic performance upon entering high school—is a key mechanism behind the continuing crisis of high school attrition. PMID:23017804

The 9th grade shock and the high school dropout crisis.

PubMed

Pharris-Ciurej, Nikolas; Hirschman, Charles; Willhoft, Joseph

2012-05-01

Retrospective questions on educational attainment in national surveys and censuses tend to over-estimate high school graduation rates by 15-20% points relative to administrative records. Administrative data on educational enrollment are, however, only available at the aggregate level (state, school district, and school levels) and the recording of inter-school transfers are generally incomplete. With access to linked individual-level administrative records from a very large "West Coast metropolitan school district" we track patterns of high school attrition and on-time high school graduation of individual students. Even with adjustments for the omission of out-of-district transfers (estimates of omission are presented), the results of this study show that failure in high school, as indexed by retention and attrition, are almost as common as on-time high school graduation. In addition to the usual risk factors of disadvantaged background, we find that the "9th grade shock"-an unpredicted decline in academic performance upon entering high school-is a key mechanism behind the continuing crisis of high school attrition. Copyright © 2011 Elsevier Inc. All rights reserved.

Continuity of Care and Health Care Utilization in Older Adults With Dementia in Fee-for-Service Medicare.

PubMed

Amjad, Halima; Carmichael, Donald; Austin, Andrea M; Chang, Chiang-Hua; Bynum, Julie P W

2016-09-01

Poor continuity of care may contribute to high health care spending and adverse patient outcomes in dementia. To examine the association between medical clinician continuity and health care utilization, testing, and spending in older adults with dementia. This was a study of an observational retrospective cohort from the 2012 national sample in fee-for-service Medicare, conducted from July to December 2015, using inverse probability weighted analysis. A total of 1 416 369 continuously enrolled, community-dwelling, fee-for-service Medicare beneficiaries 65 years or older with a claims-based dementia diagnosis and at least 4 ambulatory visits in 2012 were included. Continuity of care score measured on patient visits across physicians over 12 months. A higher continuity score is assigned to visit patterns in which a larger share of the patient's total visits are with fewer clinicians. Score range from 0 to 1 was examined in low-, medium-, and high-continuity tertiles. Outcomes include all-cause hospitalization, ambulatory care sensitive condition hospitalization, emergency department visit, imaging, and laboratory testing (computed tomographic [CT] scan of the head, chest radiography, urinalysis, and urine culture), and health care spending (overall, hospital and skilled nursing facility, and physician). Beneficiaries with dementia who had lower levels of continuity of care were younger, had a higher income, and had more comorbid medical conditions. Almost 50% of patients had at least 1 hospitalization and emergency department visit during the year. Utilization was lower with increasing level of continuity. Specifically comparing the highest- vs lowest-continuity groups, annual rates per beneficiary of hospitalization (0.83 vs 0.88), emergency department visits (0.84 vs 0.99), CT scan of the head (0.71 vs 0.83), urinalysis (0.72 vs 1.09), and health care spending (total spending, $22 004 vs $24 371) were higher with lower continuity even after accounting for sociodemographic factors and comorbidity burden (P < .001 for all comparisons). The rate of ambulatory care sensitive condition hospitalization was similar across continuity groups. Among older fee-for-service Medicare beneficiaries with a dementia diagnosis, lower continuity of care is associated with higher rates of hospitalization, emergency department visits, testing, and health care spending. Further research into these relationships, including potentially relevant clinical, clinician, and systems factors, can inform whether improving continuity of care in this population may benefit patients and the wider health system.

Judgments of aircraft noise in a traffic noise background

NASA Technical Reports Server (NTRS)

Powell, C. A.; Rice, C. G.

1975-01-01

An investigation was conducted to determine subjective response to aircraft noise in different road traffic backgrounds. In addition, two laboratory techniques for presenting the aircraft noise with the background noise were evaluated. For one technique, the background noise was continuous over an entire test session; for the other, the background noise level was changed with each aircraft noise during a session. Subjective response to aircraft noise was found to decrease with increasing background noise level, for a range of typical indoor noise levels. Subjective response was found to be highly correlated with the Noise Pollution Level (NPL) measurement scale.

Mortality related to air pollution with the moscow heat wave and wildfire of 2010.

PubMed

Shaposhnikov, Dmitry; Revich, Boris; Bellander, Tom; Bedada, Getahun Bero; Bottai, Matteo; Kharkova, Tatyana; Kvasha, Ekaterina; Lezina, Elena; Lind, Tomas; Semutnikova, Eugenia; Pershagen, Göran

2014-05-01

Prolonged high temperatures and air pollution from wildfires often occur together, and the two may interact in their effects on mortality. However, there are few data on such possible interactions. We analyzed day-to-day variations in the number of deaths in Moscow, Russia, in relation to air pollution levels and temperature during the disastrous heat wave and wildfire of 2010. Corresponding data for the period 2006-2009 were used for comparison. Daily average levels of PM10 and ozone were obtained from several continuous measurement stations. The daily number of nonaccidental deaths from specific causes was extracted from official records. Analyses of interactions considered the main effect of temperature as well as the added effect of prolonged high temperatures and the interaction with PM10. The major heat wave lasted for 44 days, with 24-hour average temperatures ranging from 24°C to 31°C and PM10 levels exceeding 300 μg/m on several days. There were close to 11,000 excess deaths from nonaccidental causes during this period, mainly among those older than 65 years. Increased risks also occurred in younger age groups. The most pronounced effects were for deaths from cardiovascular, respiratory, genitourinary, and nervous system diseases. Continuously increasing risks following prolonged high temperatures were apparent during the first 2 weeks of the heat wave. Interactions between high temperatures and air pollution from wildfires in excess of an additive effect contributed to more than 2000 deaths. Interactions between high temperatures and wildfire air pollution should be considered in risk assessments regarding health consequences of climate change.

Sustaining Lesson Study: Resources and Factors that Support and Constrain Mathematics Teachers' Ability to Continue After the Grant Ends

NASA Astrophysics Data System (ADS)

Druken, Bridget Kinsella

Lesson study, a teacher-led vehicle for inquiring into teacher practice through creating, enacting, and reflecting on collaboratively designed research lessons, has been shown to improve mathematics teacher practice in the United States, such as improving knowledge about mathematics, changing teacher practice, and developing communities of teachers. Though it has been described as a sustainable form of professional development, little research exists on what might support teachers in continuing to engage in lesson study after a grant ends. This qualitative and multi-case study investigates the sustainability of lesson study as mathematics teachers engage in a district scale-up lesson study professional experience after participating in a three-year California Mathematics Science Partnership (CaMSP) grant to improve algebraic instruction. To do so, I first provide a description of material (e.g. curricular materials and time), human (attending district trainings and interacting with mathematics coaches), and social (qualities like trust, shared values, common goals, and expectations developed through relationships with others) resources present in the context of two school districts as reported by participants. I then describe practices of lesson study reported to have continued. I also report on teachers' conceptions of what it means to engage in lesson study. I conclude by describing how these results suggest factors that supported and constrained teachers' in continuing lesson study. To accomplish this work, I used qualitative methods of grounded theory informed by a modified sustainability framework on interview, survey, and case study data about teachers, principals, and Teachers on Special Assignment (TOSAs). Four cases were selected to show the varying levels of lesson study practices that continued past the conclusion of the grant. Analyses reveal varying levels of integration, linkage, and synergy among both formally and informally arranged groups of teachers. High levels of integration and linkage among groups of teachers supported them in sustaining lesson study practices. Groups of teachers with low levels of integration but with linked individuals sustained some level of practices, whereas teachers with low levels of integration and linkage constrained them in continuing lesson study at their site. Additionally, teachers' visions of lesson study and its uses shaped the types of activities teachers engaged, with well-developed conceptions of lesson study supporting and limited visions constraining the ability to attract or align resources to continue lesson study practices. Principals' support, teacher autonomy, and cultures of collaboration or isolation were also factors that either supported or constrained teachers' ability to continue lesson study. These analyses provide practical implications on how to support mathematics teachers in continuing lesson study, and theoretical contributions on developing the construct of sustainability within mathematics education research.

Spatial and temporal controls of atoll island inundation: implications for urbanized atolls in the Marshall Islands.

NASA Astrophysics Data System (ADS)

Ford, M.; Becker, J. M.; Merrifield, M. A.

2012-12-01

Atoll islands are highly vulnerable to a range of inundation hazards. The impacts of such hazards are expected to be magnified as a result of continued sea-level rise. Both recent and historic inundation events provide unique insights into the requisite conditions necessary to initiate island inundation. A number of recent and historic inundation events are presented in order to examine the oceanographic and meteorological conditions driving inundation of a densely populated, urbanized atoll in the central Pacific. Analysis of inundation events suggests that a number of key drivers contribute to the spatial and temporal extent of island inundation, with unique degrees of predictability and resultant impact signatures apparent on island geomorphology and local anthropogenic activities. Results indicate three distinct drivers of inundation hazards exist. Firstly, tropical storms and typhoons elevate sea level through inverse barometric setup, wind setup and a range of wave driven processes and have caused considerable impact on atolls within the Marshall Islands. Secondly, super-elevated sea level conditions resulting from the combination of seasonal high tides and quasi-cyclical La Nina conditions drive inundation of low-lying lagoon facing coastal areas. Thirdly, long period swell conditions, typically generated by distant storms, can elevate reef-flat water levels through wave setup and infragravity wave oscillations. Such wave conditions can over wash the ocean-facing island ridge, often inundating large sections of the island. Reef-flat wave conditions are tidally modulated, with inundation events typically occurring around high tide. However, the two most recent destructive swell-driven inundation events have occurred while tide levels were significantly lower than spring tide levels, suggesting high water levels are not a necessary prerequisite for wave-driven inundation. The different modes of inundation are discussed and grounded within recent and historic inundation events, as well as results of a lengthy reef flat wave observation dataset from Kwajalein and Majuro Atolls in the Republic of the Marshall Islands. Future impacts of continued sea-level rise are considered on each mode of island inundation and the implications for local response discussed within the context of urbanised atoll islands.

Decomposing an urban soundscape to reveal patterns and drivers of variation in anthropogenic noise.

PubMed

Gill, Sharon A; Grabarczyk, Erin E; Baker, Kathleen M; Naghshineh, Koorosh; Vonhof, Maarten J

2017-12-01

Continuous and intermittent noise may have different effects on humans and wildlife, therefore distinguishing temporal patterns of noise and their drivers is important for policy regarding both public health and wildlife management. We visualized patterns and explored land-use drivers of continuous and high-amplitude intermittent sound pressure levels (SPLs) on an urban campus in Michigan, U.S.A. To visualize patterns of SPLs, we introduce decibel duration curves (DDCs), which show the cumulative frequency distribution of SPLs and aid in the interpretation of statistical SPLs (L n values) that reflect continuous versus intermittent sounds. DDCs and L n values reveal that our 24 recording locations varied in the intensity of both continuous and intermittent noise, with intermittent high-amplitude sound events in particular contributing to variability in SPLs over the study site. Time of day influenced both continuous and intermittent SPLs, as locations relatively close to manmade structures (buildings, roads and parking lots) experienced higher SPLs as the day progressed. Continuous SPLs increased with decreasing distance to manmade structures, whereas intermittent SPLs increased with decreasing distance to roads and increasing distance to buildings. Thus, different land-use factors influenced patterns of continuous and intermittent noise, which suggests that different policy and strategies may be needed to ameliorate their effects on the public and wildlife. Copyright © 2017 Elsevier B.V. All rights reserved.

An investigation of signal performance enhancements achieved through innovative pixel design across several generations of indirect detection, active matrix, flat-panel arrays

PubMed Central

Antonuk, Larry E.; Zhao, Qihua; El-Mohri, Youcef; Du, Hong; Wang, Yi; Street, Robert A.; Ho, Jackson; Weisfield, Richard; Yao, William

2009-01-01

Active matrix flat-panel imager (AMFPI) technology is being employed for an increasing variety of imaging applications. An important element in the adoption of this technology has been significant ongoing improvements in optical signal collection achieved through innovations in indirect detection array pixel design. Such improvements have a particularly beneficial effect on performance in applications involving low exposures and∕or high spatial frequencies, where detective quantum efficiency is strongly reduced due to the relatively high level of additive electronic noise compared to signal levels of AMFPI devices. In this article, an examination of various signal properties, as determined through measurements and calculations related to novel array designs, is reported in the context of the evolution of AMFPI pixel design. For these studies, dark, optical, and radiation signal measurements were performed on prototype imagers incorporating a variety of increasingly sophisticated array designs, with pixel pitches ranging from 75 to 127 μm. For each design, detailed measurements of fundamental pixel-level properties conducted under radiographic and fluoroscopic operating conditions are reported and the results are compared. A series of 127 μm pitch arrays employing discrete photodiodes culminated in a novel design providing an optical fill factor of ∼80% (thereby assuring improved x-ray sensitivity), and demonstrating low dark current, very low charge trapping and charge release, and a large range of linear signal response. In two of the designs having 75 and 90 μm pitches, a novel continuous photodiode structure was found to provide fill factors that approach the theoretical maximum of 100%. Both sets of novel designs achieved large fill factors by employing architectures in which some, or all of the photodiode structure was elevated above the plane of the pixel addressing transistor. Generally, enhancement of the fill factor in either discrete or continuous photodiode arrays was observed to result in no degradation in MTF due to charge sharing between pixels. While the continuous designs exhibited relatively high levels of charge trapping and release, as well as shorter ranges of linearity, it is possible that these behaviors can be addressed through further refinements to pixel design. Both the continuous and the most recent discrete photodiode designs accommodate more sophisticated pixel circuitry than is present on conventional AMFPIs – such as a pixel clamp circuit, which is demonstrated to limit signal saturation under conditions corresponding to high exposures. It is anticipated that photodiode structures such as the ones reported in this study will enable the development of even more complex pixel circuitry, such as pixel-level amplifiers, that will lead to further significant improvements in imager performance. PMID:19673228

10 CFR 63.302 - Definitions for Subpart L.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Definitions for Subpart L. 63.302 Section 63.302 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... hydraulic conductivity, gradient, and the screened interval. Yucca Mountain disposal system means the...

10 CFR 63.302 - Definitions for Subpart L.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Definitions for Subpart L. 63.302 Section 63.302 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... hydraulic conductivity, gradient, and the screened interval. Yucca Mountain disposal system means the...

10 CFR 63.302 - Definitions for Subpart L.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Definitions for Subpart L. 63.302 Section 63.302 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... hydraulic conductivity, gradient, and the screened interval. Yucca Mountain disposal system means the...

10 CFR 72.9 - Information collection requirements: OMB approval.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Information collection requirements: OMB approval. 72.9 Section 72.9 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.26 - Contents of application: Technical specifications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Contents of application: Technical specifications. 72.26 Section 72.26 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.7 - Specific exemptions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Specific exemptions. 72.7 Section 72.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.7...

10 CFR 72.9 - Information collection requirements: OMB approval.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Information collection requirements: OMB approval. 72.9 Section 72.9 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.20 - Public inspection of application.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Public inspection of application. 72.20 Section 72.20 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE License...

10 CFR 72.7 - Specific exemptions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Specific exemptions. 72.7 Section 72.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.7...

10 CFR 60.75 - Inspections.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Inspections. 60.75 Section 60.75 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Records, Reports, Tests, and Inspections § 60.75 Inspections. (a) DOE shall allow the Commission to inspect the premises...

10 CFR 60.47 - Facility information and verification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Facility information and verification. 60.47 Section 60.47 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Us/iaea Safeguards Agreement § 60.47 Facility information and verification. (a) In...

An Examination of Principal Job Satisfaction

ERIC Educational Resources Information Center

Pengilly, Michelle M.

2010-01-01

As education continues to succumb to deficits in budgets and increasingly high levels of student performance to meet the federal and state mandates, the quest to sustain and retain successful principals is imperative. The National Association of School Boards (1999) portrays effective principals as "linchpins" of school improvement and…

10 CFR 72.30 - Financial assurance and recordkeeping for decommissioning.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Financial assurance and recordkeeping for decommissioning. 72.30 Section 72.30 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN...

10 CFR 72.70 - Safety analysis report updating.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Safety analysis report updating. 72.70 Section 72.70 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Records...

10 CFR 72.20 - Public inspection of application.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Public inspection of application. 72.20 Section 72.20 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE License...

10 CFR 72.96 - Siting limitations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Siting limitations. 72.96 Section 72.96 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL... high-level radioactive waste that may be stored. This limitation shall prohibit the storage of a...

10 CFR 72.26 - Contents of application: Technical specifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Contents of application: Technical specifications. 72.26 Section 72.26 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

Achieving Zero Net Migration.

ERIC Educational Resources Information Center

Mann, Donald

1984-01-01

Unemployment in the United States can only be made worse by continued high levels of legal immigration. Especially serious is the threat from Latin America. We must help developing countries halt their population growth and impose a ceiling of 100,000 a year for total immigration to the United States. (RM)

10 CFR 60.181 - Violations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Violations. 60.181 Section 60.181 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES... violation of the provisions of— (1) The Atomic Energy Act of 1954, as amended; (2) Title II of the Energy...

10 CFR 60.181 - Violations.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Violations. 60.181 Section 60.181 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES... violation of the provisions of— (1) The Atomic Energy Act of 1954, as amended; (2) Title II of the Energy...

10 CFR 60.183 - Criminal penalties.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Criminal penalties. 60.183 Section 60.183 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Violations § 60.183 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended...

10 CFR 60.183 - Criminal penalties.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Criminal penalties. 60.183 Section 60.183 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Violations § 60.183 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended...

10 CFR 60.183 - Criminal penalties.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Criminal penalties. 60.183 Section 60.183 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Violations § 60.183 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended...

10 CFR 60.181 - Violations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Violations. 60.181 Section 60.181 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES... violation of the provisions of— (1) The Atomic Energy Act of 1954, as amended; (2) Title II of the Energy...

10 CFR 60.6 - Exemptions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Exemptions. 60.6 Section 60.6 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.6 Exemptions. The Commission may, upon application by DOE, any interested person, or upon its own...

10 CFR 60.181 - Violations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Violations. 60.181 Section 60.181 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES... violation of the provisions of— (1) The Atomic Energy Act of 1954, as amended; (2) Title II of the Energy...

10 CFR 60.183 - Criminal penalties.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Criminal penalties. 60.183 Section 60.183 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Violations § 60.183 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended...

10 CFR 60.6 - Exemptions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Exemptions. 60.6 Section 60.6 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.6 Exemptions. The Commission may, upon application by DOE, any interested person, or upon its own...

10 CFR 60.3 - License required.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false License required. 60.3 Section 60.3 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.3 License required. (a) DOE shall not receive or possess source, special nuclear, or...

10 CFR 60.3 - License required.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false License required. 60.3 Section 60.3 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.3 License required. (a) DOE shall not receive or possess source, special nuclear, or...

10 CFR 60.3 - License required.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false License required. 60.3 Section 60.3 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.3 License required. (a) DOE shall not receive or possess source, special nuclear, or...

10 CFR 60.43 - License specification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false License specification. 60.43 Section 60.43 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses License Issuance and Amendment § 60.43 License specification. (a) A license issued under this part shall...

10 CFR 60.183 - Criminal penalties.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Criminal penalties. 60.183 Section 60.183 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Violations § 60.183 Criminal penalties. (a) Section 223 of the Atomic Energy Act of 1954, as amended...

10 CFR 60.9 - Employee protection.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Employee protection. 60.9 Section 60.9 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.9 Employee protection. (a) Discrimination by a Commission licensee, an applicant for a...

10 CFR 60.133 - Additional design criteria for the underground facility.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Additional design criteria for the underground facility. 60.133 Section 60.133 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Design Criteria for the Geologic Repository...

10 CFR 60.10 - Completeness and accuracy of information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Completeness and accuracy of information. 60.10 Section 60.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.10 Completeness and accuracy of information. (a) Information...

10 CFR 60.181 - Violations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Violations. 60.181 Section 60.181 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Violations § 60.181 Violations. (a) The Commission may obtain an injunction or other court order to prevent a...

10 CFR 60.16 - Site characterization plan required.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Site characterization plan required. 60.16 Section 60.16 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses Preapplication Review § 60.16 Site characterization plan required. Before proceeding to...

10 CFR 60.6 - Exemptions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Exemptions. 60.6 Section 60.6 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.6 Exemptions. The Commission may, upon application by DOE, any interested person, or upon its own...

10 CFR 60.11 - Deliberate misconduct.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Deliberate misconduct. 60.11 Section 60.11 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.11 Deliberate misconduct. (a) Any licensee, applicant for a license, employee of a licensee...

10 CFR 60.161 - Training and certification program.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Training and certification program. 60.161 Section 60.161 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Training and Certification of Personnel § 60.161 Training and certification program. DOE shall...

10 CFR 72.11 - Completeness and accuracy of information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Completeness and accuracy of information. 72.11 Section 72.11 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.11 - Completeness and accuracy of information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Completeness and accuracy of information. 72.11 Section 72.11 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.78 - Nuclear material transaction reports.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Nuclear material transaction reports. 72.78 Section 72.78 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Records...

10 CFR 72.11 - Completeness and accuracy of information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Completeness and accuracy of information. 72.11 Section 72.11 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.78 - Nuclear material transaction reports.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Nuclear material transaction reports. 72.78 Section 72.78 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Records...

10 CFR 72.78 - Nuclear material transaction reports.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Nuclear material transaction reports. 72.78 Section 72.78 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Records...

10 CFR 72.78 - Nuclear material transaction reports.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Nuclear material transaction reports. 72.78 Section 72.78 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Records...

10 CFR 72.11 - Completeness and accuracy of information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Completeness and accuracy of information. 72.11 Section 72.11 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.11 - Completeness and accuracy of information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Completeness and accuracy of information. 72.11 Section 72.11 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 63.144 - Quality assurance program change.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Quality assurance program change. 63.144 Section 63.144 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... assurance program information that duplicates language in quality assurance regulatory guides and quality...

10 CFR 60.150 - Scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Scope. 60.150 Section 60.150 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Quality Assurance § 60.150 Scope. As used in this part, quality assurance comprises all those planned and systematic...

Lay or Lie?

ERIC Educational Resources Information Center

Dubois, Barbara R.

1983-01-01

THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT: LEVEL: High school and college. AUTHOR'S COMMENT: Many would like to abandon the distinction between "lay" and "lie," but I still receive enough questions about it to continue teaching it. Finding that students did not believe me when I taught them to substitute…

10 CFR 72.124 - Criteria for nuclear criticality safety.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Criteria for nuclear criticality safety. 72.124 Section 72.124 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.124 - Criteria for nuclear criticality safety.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Criteria for nuclear criticality safety. 72.124 Section 72.124 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.124 - Criteria for nuclear criticality safety.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Criteria for nuclear criticality safety. 72.124 Section 72.124 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.124 - Criteria for nuclear criticality safety.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Criteria for nuclear criticality safety. 72.124 Section 72.124 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.124 - Criteria for nuclear criticality safety.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Criteria for nuclear criticality safety. 72.124 Section 72.124 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 60.142 - Design testing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... construction, a program for in situ testing of such features as borehole and shaft seals, backfill, and the... 10 Energy 2 2010-01-01 2010-01-01 false Design testing. 60.142 Section 60.142 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

10 CFR 60.142 - Design testing.

Code of Federal Regulations, 2013 CFR

2013-01-01

... construction, a program for in situ testing of such features as borehole and shaft seals, backfill, and the... 10 Energy 2 2013-01-01 2013-01-01 false Design testing. 60.142 Section 60.142 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

10 CFR 60.142 - Design testing.

Code of Federal Regulations, 2012 CFR

2012-01-01

... construction, a program for in situ testing of such features as borehole and shaft seals, backfill, and the... 10 Energy 2 2012-01-01 2012-01-01 false Design testing. 60.142 Section 60.142 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

10 CFR 60.142 - Design testing.

Code of Federal Regulations, 2014 CFR

2014-01-01

... construction, a program for in situ testing of such features as borehole and shaft seals, backfill, and the... 10 Energy 2 2014-01-01 2014-01-01 false Design testing. 60.142 Section 60.142 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

10 CFR 60.142 - Design testing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... construction, a program for in situ testing of such features as borehole and shaft seals, backfill, and the... 10 Energy 2 2011-01-01 2011-01-01 false Design testing. 60.142 Section 60.142 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES...

10 CFR 63.33 - Amendment of construction authorization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Amendment of construction authorization. 63.33 Section 63.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.33 Amendment of...

10 CFR 63.33 - Amendment of construction authorization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Amendment of construction authorization. 63.33 Section 63.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.33 Amendment of...

10 CFR 63.32 - Conditions of construction authorization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Conditions of construction authorization. 63.32 Section 63.32 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.32 Conditions of...

10 CFR 63.32 - Conditions of construction authorization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Conditions of construction authorization. 63.32 Section 63.32 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.32 Conditions of...

10 CFR 63.32 - Conditions of construction authorization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Conditions of construction authorization. 63.32 Section 63.32 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.32 Conditions of...

10 CFR 63.33 - Amendment of construction authorization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Amendment of construction authorization. 63.33 Section 63.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.33 Amendment of...

10 CFR 63.33 - Amendment of construction authorization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Amendment of construction authorization. 63.33 Section 63.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.33 Amendment of...

10 CFR 63.33 - Amendment of construction authorization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Amendment of construction authorization. 63.33 Section 63.33 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.33 Amendment of...

10 CFR 63.32 - Conditions of construction authorization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Conditions of construction authorization. 63.32 Section 63.32 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Licenses Construction Authorization § 63.32 Conditions of...

Time Exceedances for High Intensity Solar Proton Fluxes

NASA Technical Reports Server (NTRS)

Xapsos, Michael A.; Stauffer, Craig A.; Jordan, Thomas M.; Adam, James H., Jr.; Dietrich, William F.

2011-01-01

A model is presented for times during a space mission that specified solar proton flux levels are exceeded. This includes both total time and continuous time periods during missions. Results for the solar maximum and solar minimum phases of the solar cycle are presented and compared for a broad range of proton energies and shielding levels. This type of approach is more amenable to reliability analysis for spacecraft systems and instrumentation than standard statistical models.

Periods of High Intensity Solar Proton Flux

NASA Technical Reports Server (NTRS)

Xapsos, Michael A.; Stauffer, Craig A.; Jordan, Thomas M.; Adams, James H.; Dietrich, William F.

2012-01-01

Analysis is presented for times during a space mission that specified solar proton flux levels are exceeded. This includes both total time and continuous time periods during missions. Results for the solar maximum and solar minimum phases of the solar cycle are presented and compared for a broad range of proton energies and shielding levels. This type of approach is more amenable to reliability analysis for spacecraft systems and instrumentation than standard statistical models.

Prognosis and continuity of child mental health problems from preschool to primary school: results of a four-year longitudinal study.

PubMed

Beyer, Thomas; Postert, Christian; Müller, Jörg M; Furniss, Tilman

2012-08-01

In a four-year longitudinal study, changes in and continuity of behavioral and emotional problems were examined in 814 subjects from kindergarten to primary school. Mental health problems were assessed by means of the Child Behavior Checklist (CBCL). The distribution of the CBCL broadband groups revealed a high level of continuity of internalizing symptoms over the four-year period and a shift from externalizing symptoms at baseline towards a combination of internalizing and externalizing symptoms at follow-up. The presence of mental health problems at follow-up was correlated with gender (higher amongst boys), pre-existing mental health problems at baseline, and separation or divorce of the parents, but not with single-family status or the age and educational level of the mother. The increasing number of children with a combination of internalizing and externalizing symptoms demonstrates the increasing complexity of child mental health problems in the developmental span from preschool age to school age.

Continuity and Change From Full-Inclusion Early Childhood Programs Through the Early Elementary Period

PubMed Central

Guralnick, Michael J.; Neville, Brian; Hammond, Mary A.; Connor, Robert T.

2010-01-01

A large and well-characterized group of children with mild developmental delays initially enrolled in full-inclusion preschool or kindergarten programs was followed for 3 years. Changes in the type of inclusive placements as children transitioned to first and second grades were monitored, and associations between placement type and child and family characteristics were examined. Results revealed a high level of continuity in that most children remained in partial or full inclusion settings over time. However, a substantial reduction in full-inclusion placements occurred between the 2nd and 3rd year when children were completing the transition to first and second grades. Placements in less inclusive settings were associated with children’s levels of cognitive and language development but not their adaptive, social, or behavioral characteristics. A hypothesis was put forward that placement in full-inclusion programs during the early childhood years creates a momentum to continue maximum participation in inclusive settings over time. PMID:20890373

Expanded Quality Management Using Information Power (EQUIP): protocol for a quasi-experimental study to improve maternal and newborn health in Tanzania and Uganda

PubMed Central

2014-01-01

Background Maternal and newborn mortality remain unacceptably high in sub-Saharan Africa. Tanzania and Uganda are committed to reduce maternal and newborn mortality, but progress has been limited and many essential interventions are unavailable in primary and referral facilities. Quality management has the potential to overcome low implementation levels by assisting teams of health workers and others finding local solutions to problems in delivering quality care and the underutilization of health services by the community. Existing evidence of the effect of quality management on health worker performance in these contexts has important limitations, and the feasibility of expanding quality management to the community level is unknown. We aim to assess quality management at the district, facility, and community levels, supported by information from high-quality, continuous surveys, and report effects of the quality management intervention on the utilization and quality of services in Tanzania and Uganda. Methods In Uganda and Tanzania, the Expanded Quality Management Using Information Power (EQUIP) intervention is implemented in one intervention district and evaluated using a plausibility design with one non-randomly selected comparison district. The quality management approach is based on the collaborative model for improvement, in which groups of quality improvement teams test new implementation strategies (change ideas) and periodically meet to share results and identify the best strategies. The teams use locally-generated community and health facility data to monitor improvements. In addition, data from continuous health facility and household surveys are used to guide prioritization and decision making by quality improvement teams as well as for evaluation of the intervention. These data include input, process, output, coverage, implementation practice, and client satisfaction indicators in both intervention and comparison districts. Thus, intervention districts receive quality management and continuous surveys, and comparison districts-only continuous surveys. Discussion EQUIP is a district-scale, proof-of-concept study that evaluates a quality management approach for maternal and newborn health including communities, health facilities, and district health managers, supported by high-quality data from independent continuous household and health facility surveys. The study will generate robust evidence about the effectiveness of quality management and will inform future nationwide implementation approaches for health system strengthening in low-resource settings. Trial registration PACTR201311000681314 PMID:24690284

Expanded Quality Management Using Information Power (EQUIP): protocol for a quasi-experimental study to improve maternal and newborn health in Tanzania and Uganda.

PubMed

Hanson, Claudia; Waiswa, Peter; Marchant, Tanya; Marx, Michael; Manzi, Fatuma; Mbaruku, Godfrey; Rowe, Alex; Tomson, Göran; Schellenberg, Joanna; Peterson, Stefan

2014-04-02

Maternal and newborn mortality remain unacceptably high in sub-Saharan Africa. Tanzania and Uganda are committed to reduce maternal and newborn mortality, but progress has been limited and many essential interventions are unavailable in primary and referral facilities. Quality management has the potential to overcome low implementation levels by assisting teams of health workers and others finding local solutions to problems in delivering quality care and the underutilization of health services by the community. Existing evidence of the effect of quality management on health worker performance in these contexts has important limitations, and the feasibility of expanding quality management to the community level is unknown. We aim to assess quality management at the district, facility, and community levels, supported by information from high-quality, continuous surveys, and report effects of the quality management intervention on the utilization and quality of services in Tanzania and Uganda. In Uganda and Tanzania, the Expanded Quality Management Using Information Power (EQUIP) intervention is implemented in one intervention district and evaluated using a plausibility design with one non-randomly selected comparison district. The quality management approach is based on the collaborative model for improvement, in which groups of quality improvement teams test new implementation strategies (change ideas) and periodically meet to share results and identify the best strategies. The teams use locally-generated community and health facility data to monitor improvements. In addition, data from continuous health facility and household surveys are used to guide prioritization and decision making by quality improvement teams as well as for evaluation of the intervention. These data include input, process, output, coverage, implementation practice, and client satisfaction indicators in both intervention and comparison districts. Thus, intervention districts receive quality management and continuous surveys, and comparison districts-only continuous surveys. EQUIP is a district-scale, proof-of-concept study that evaluates a quality management approach for maternal and newborn health including communities, health facilities, and district health managers, supported by high-quality data from independent continuous household and health facility surveys. The study will generate robust evidence about the effectiveness of quality management and will inform future nationwide implementation approaches for health system strengthening in low-resource settings. PACTR201311000681314.

Legionnaires' disease associated with a hospital water system. A five-year progress report on continuous hyperchlorination.

PubMed

Helms, C M; Massanari, R M; Wenzel, R P; Pfaller, M A; Moyer, N P; Hall, N

In 1981, sixteen cases of nosocomial legionellosis occurred among 456 patients admitted to a new hematology-oncology unit (35 per 1000 admissions). Monoclonal antibody typing and restriction endonuclease plasmid analysis identified a unique strain (09,04) of Legionella pneumophila serogroup 1 isolated from both patients and water outlets. Continuous hyperchlorination of the hot and cold water began in January 1982, and chlorine levels of 3 to 5 mg/L have been maintained most recently. Water samples have been consistently negative for Legionella for more than five years. Four sporadic cases of nosocomial legionellosis have occurred in the hematology-oncology unit during the same period (one per 1000 admissions) associated with a different strain of L pneumophila serogroup 1 (09,00). The environmental reservoir(s) of L pneumophila serogroup 1 in these cases has not been identified. Levels of trihalomethanes (potential carcinogens) were high (greater than 100 micrograms/L) when chlorine levels of hot water exceeded 4 mg/L. Some corrosion damage to the water distribution system has occurred: the average number of leaks per month increased steadily from zero in 1982 to 5.2 in 1986. The chlorinator installation costs were +75,800, and annual operation expenses were +12,500. Continuous hyperchlorination is a promising but still experimental technique for control of nosocomial legionellosis. In our experience, epidemic disease has been controlled, but sporadic cases have continued to occur.

Project NOAH: Regulating modern sea-level rise. Phase II: Jerusalem Underground

NASA Astrophysics Data System (ADS)

Newman, Walter S.; Fairbridge, Rhodes W.

This proposal builds a high-speed inter-urban express between Jerusalem and Tel Aviv, generates 1500 megawatts of hydroelectric energy, curtails littoral erosion, builds a port along the Israeli Mediterranean coast and demands peaceful cooperation on both sides of the Jordan River. Phase II represents a pilot project demonstrating the feasibility of continuing to regulate world sea-level by a new series of water regulation schemes. Phase I previously described all those projects already completed or underway which have inadvertently and/or unintentionally served the purpose of sea-level regulation. These forms of Phase I sea-level regulation include large and small reservoirs, irrigation projects, water infiltration schemes, farm ponds, and swimming and reflecting pools. All these water storage projects have already exercised a very appreciable brake on 20th century sea-level rise. Phase II outlines a high-visibility proposal which will serve to illustrate the viability of “Project NOAH”.

Coordination as a function of skill level in the gymnastics longswing.

PubMed

Williams, Genevieve K R; Irwin, Gareth; Kerwin, David G; Hamill, Joseph; Van Emmerik, Richard E A; Newell, Karl M

2016-01-01

The purpose of this study was to investigate the nature of inter-joint coordination at different levels of skilled performance to: (1) distinguish learners who were successful versus unsuccessful in terms of their task performance; (2) investigate the pathways of change during the learning of a new coordination pattern and (3) examine how the learner's coordination patterns relate to those of experts in the longswing gymnastics skill. Continuous relative phase of hip and shoulder joint motions was examined for longswings performed by two groups of novices, successful (n = 4) and unsuccessful (n = 4) over five practice sessions, and two expert gymnasts. Principal component analysis showed that during longswing positions where least continuous relative phase variability occurred for expert gymnasts, high variability distinguished the successful from the unsuccessful novice group. Continuous relative phase profiles of successful novices became more out-of-phase over practice and less similar to the closely in-phase coupling of the expert gymnasts. Collectively, the findings support the proposition that at the level in inter-joint coordination a technique emerges that facilitates successful performance but is not more like an expert's movement coordination. This finding questions the appropriateness of inferring development towards a "gold champion" movement coordination.

Consistency of Continuous Ambulatory Interstitial Glucose Monitoring Sensors.

PubMed

Wu, Pei T; Segovia, David E; Lee, Cathy C; Nguyen, Kim-Lien

2018-05-16

The abdominal region is the most common location for continuous glucose monitor (CGM) sensor insertion. However, a paucity of post-marketing data is available to demonstrate intra-individual consistency of CGM readings at different abdominal insertion sites. Healthy adults (fasting glucose (FG) < 5.5 mmol/L; BMI < 30 kg/m²) were recruited and a CGM sensor was placed on each side of the abdomen. Postprandial and continuous 48-h interstitial glucose levels were analyzed. There was no significant difference in the 3-h postprandial glucose (PPG) level derived from the left versus right CGM, which remained non-significant after adjusting for waist circumference or FG. Among the glucose levels recorded over 48-h, values on the left site were greater in 3.6% of the data points ( p < 0.05). After adjusting for waist circumference, only 0.5% of the glucose values remained significantly greater on the left ( p < 0.05). When adjusted for FG, similar results were observed. For both PPG and 48-h readings, the mean absolute relative difference was not significant between the two abdominal sites. CGM-derived glucose measures were highly consistent between the left and right abdomen during both the postprandial and post-absorptive periods.

Factors that allow elderly individuals to stay at home with their families using the Japanese long-term care insurance system.

PubMed

Oyama, Yumiko; Tamiya, Nanako; Kashiwagi, Masayo; Sato, Mikiya; Ohwaki, Kazuhiro; Yano, Eiji

2013-07-01

This study examined the factors that allow elderly individuals to stay at home continuously by considering the roles of the family caregiver, the use of services and characteristics of the elderly individual. We analyzed 432 elderly individuals living at home with family. The outcome was that participants remained at home continuously over a 24-month period. The participants were stratified into two care-needs levels, and then multiple logistic regression analyses were carried out to examine relationships between staying at home and the Japanese version of the Zarit Burden Interview (J-ZBI), public Long-term Care Insurance (LTCI) service use, family caregivers' characteristics and elderly peoples' characteristics. Low scores on the J-ZBI were related to outcome in both care-needs subgroups (low care-needs subgroup: OR 2.11; 95% CI 1.31-3.43, high care-needs subgroup: OR 5.03; 95% CI 1.04-31.1). Regarding LTCI services, the use of home-visit nursing (HN) service was related to staying at home continuously in the high care-needs group (OR 37.39; 95% CI 3.31-879.1). Alleviation of caregiver' burden was essential for continuous stay at home of elderly people regardless of care-needs levels. Also, the HN service was founded as the relevant LTCI service factor for staying at home continuously. The HN service use might affect the outcome when we consider the causal relationship. Therefore, the policy for the promotion of HN service use will be important to achieve the ultimate goal of LTCI, which is to allow elderly people to live in their communities for as long as possible. © 2012 Japan Geriatrics Society.

Effects on carbon monoxide levels in mobile homes using unvented kerosene heaters for residential heating

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, R.; Walsh, D.; White, J.

1992-01-01

Carbon monoxide (CO) emission levels were continuously monitored in 8 mobile trailer homes less than 10 years old. These homes were monitored in an US EPA study on indoor air quality as affected by unvented portable kerosene heaters. Respondents were asked to operate their heaters in a normal fashion. CO, air exchange and temperature values were measured during the study in each home. Results indicate that consumers using unvented kerosene heaters may be unknowingly exposed to high CO levels without taking proper precautions.

A Human Serum-Based Enzyme-Free Continuous Glucose Monitoring Technique Using a Needle-Type Bio-Layer Interference Sensor

PubMed Central

Seo, Dongmin; Paek, Sung-Ho; Oh, Sangwoo; Seo, Sungkyu; Paek, Se-Hwan

2016-01-01

The incidence of diabetes is continually increasing, and by 2030, it is expected to have increased by 69% and 20% in underdeveloped and developed countries, respectively. Therefore, glucose sensors are likely to remain in high demand in medical device markets. For the current study, we developed a needle-type bio-layer interference (BLI) sensor that can continuously monitor glucose levels. Using dialysis procedures, we were able to obtain hypoglycemic samples from commercial human serum. These dialysis-derived samples, alongside samples of normal human serum were used to evaluate the utility of the sensor for the detection of the clinical interest range of glucose concentrations (70–200 mg/dL), revealing high system performance for a wide glycemic state range (45–500 mg/dL). Reversibility and reproducibility were also tested over a range of time spans. Combined with existing BLI system technology, this sensor holds great promise for use as a wearable online continuous glucose monitoring system for patients in a hospital setting. PMID:27669267

High-power, single-frequency, continuous-wave second-harmonic-generation of ytterbium fiber laser in PPKTP and MgO:sPPLT.

PubMed

Kumar, S Chaitanya; Samanta, G K; Ebrahim-Zadeh, M

2009-08-03

Characteristics of high-power, narrow-linewidth, continuous-wave (cw) green radiation obtained by simple single-pass second-harmonic-generation (SHG) of a cw ytterbium fiber laser at 1064 nm in the nonlinear crystals of PPKTP and MgO:sPPLT are studied and compared. Temperature tuning and SHG power scaling up to nearly 10 W for input fundamental power levels up to 30 W are performed. Various contributions to thermal effects in both crystals, limiting the SHG conversion efficiency, are studied. Optimal focusing conditions and thermal management schemes are investigated to maximize SHG performance in MgO:sPPLT. Stable green output power and high spatial beam quality with M(2)<1.33 and M(2)<1.34 is achieved in MgO:sPPLT and PPKTP, respectively.

High performance reconciliation for continuous-variable quantum key distribution with LDPC code

NASA Astrophysics Data System (ADS)

Lin, Dakai; Huang, Duan; Huang, Peng; Peng, Jinye; Zeng, Guihua

2015-03-01

Reconciliation is a significant procedure in a continuous-variable quantum key distribution (CV-QKD) system. It is employed to extract secure secret key from the resulted string through quantum channel between two users. However, the efficiency and the speed of previous reconciliation algorithms are low. These problems limit the secure communication distance and the secure key rate of CV-QKD systems. In this paper, we proposed a high-speed reconciliation algorithm through employing a well-structured decoding scheme based on low density parity-check (LDPC) code. The complexity of the proposed algorithm is reduced obviously. By using a graphics processing unit (GPU) device, our method may reach a reconciliation speed of 25 Mb/s for a CV-QKD system, which is currently the highest level and paves the way to high-speed CV-QKD.

Design of Highly Selective Platinum Nanoparticle Catalysts for the Aerobic Oxidation of KA-Oil using Continuous-Flow Chemistry.

PubMed

Gill, Arran M; Hinde, Christopher S; Leary, Rowan K; Potter, Matthew E; Jouve, Andrea; Wells, Peter P; Midgley, Paul A; Thomas, John M; Raja, Robert

2016-03-08

Highly active and selective aerobic oxidation of KA-oil to cyclohexanone (precursor for adipic acid and ɛ-caprolactam) has been achieved in high yields using continuous-flow chemistry by utilizing uncapped noble-metal (Au, Pt & Pd) nanoparticle catalysts. These are prepared using a one-step in situ methodology, within three-dimensional porous molecular architectures, to afford robust heterogeneous catalysts. Detailed spectroscopic characterization of the nature of the active sites at the molecular level, coupled with aberration-corrected scanning transmission electron microscopy, reveals that the synthetic methodology and associated activation procedures play a vital role in regulating the morphology, shape and size of the metal nanoparticles. These active centers have a profound influence on the activation of molecular oxygen for selective catalytic oxidations. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Preserved function of the plasma membrane calcium pump of red blood cells from diabetic subjects with high levels of glycated haemoglobin.

PubMed

Bookchin, Robert M; Etzion, Zipora; Lew, Virgilio L; Tiffert, Teresa

2009-03-01

The activity of the plasma membrane Ca(2+)-pump decreases steeply throughout the 120 days lifespan of normal human red blood cells. Experiments with isolated membrane preparations showed that glycation of a lysine residue near the catalytic site of the pump ATPase had a powerful inhibitory effect. This prompted the question of whether glycation is the mechanism of age-related decline in pump activity in vivo. It is important to investigate this mechanism because the Ca(2+) pump is a major regulator of Ca(2+) homeostasis in all cells. Its impaired activity in diabetic patients, continuously exposed to high glycation rates, may thus contribute to varied tissue pathology in this disease. We measured Ca(2+)-pump activity as a function of red cell age in red cells from diabetics continuously exposed to high glucose concentrations, as documented by their high mean levels of glycated haemoglobin. The distribution of Ca(2+)-pump activities was indistinguishable from that in non-diabetics, and the pattern of activity decline with cell age in the diabetics' red cells was identical to that observed in red cells from non-diabetics. These results indicate that in intact cells the Ca(2+) pump is protected from glycation-induced inactivation.

Analysis of enzyme production by submerged culture of Aspergillus oryzae using whole barley.

PubMed

Masuda, Susumu; Kikuchi, Kaori; Matsumoto, Yuko; Sugimoto, Toshikazu; Shoji, Hiroshi; Tanabe, Masayuki

2009-10-01

We have reported on high enzyme production by submerged culture of Aspergillus kawachii using barley with the husk (whole barley). To elucidate the mechanism underlying this high enzyme production, we performed a detailed analysis. Aspergillus oryzae RIB40 was submerged-cultured using whole barley and milled whole barley. Enzyme production was analyzed in terms of changes in medium components and gene expression levels. When whole barley was used, high production of glucoamylase and alpha-amylase and high gene expression levels of these enzymes were observed. Low ammonium concentrations were maintained with nitrate ion uptake continuing into the late stage using whole barley. These findings suggest that the sustainability of nitrogen metabolism is related to high enzyme production, and that a mechanism other than that associated with the conventional amylase expression system is involved in this relationship.

Evaluating the causes of photovoltaics cost reduction: Why is PV different?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trancik, Jessika; McNerney, James; Kavlak, Goksin

The goals of this project were to quantify sources of cost reduction in photovoltaics (PV), improve theories of technological evolution, develop new analytical methods, and formu- late guidelines for continued cost reduction in photovoltaics. A number of explanations have been suggested for why photovoltaics have come down in cost rapidly over time, including increased production rates, significant R&D expenditures, heavy patenting ac- tivity, decreasing material and input costs, scale economies, reduced plant construction costs, and higher conversion efficiencies. We classified these proposed causes into low- level factors and high-level drivers. Low-level factors include technical characteristics, such as module efficiency ormore » wafer area, which are easily posed in terms of variables of a cost equation. High-level factors include scale economies, research and development (R&D), and learning-by-doing.« less

10 CFR 72.16 - Filing of application for specific license.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Filing of application for specific license. 72.16 Section 72.16 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 60.52 - Termination of license.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Termination of license. 60.52 Section 60.52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses... repository: (1) That the final disposition of radioactive wastes has been made in conformance with the DOE's...

10 CFR 60.78 - Material control and accounting records and reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Material control and accounting records and reports. 60.78 Section 60.78 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Records, Reports, Tests, and Inspections § 60.78 Material control and...

10 CFR 72.60 - Modification, revocation, and suspension of license.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Modification, revocation, and suspension of license. 72.60 Section 72.60 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.246 - Issuance of amendment to a certificate of compliance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Issuance of amendment to a certificate of compliance. 72.246 Section 72.246 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN...

10 CFR 72.230 - Procedures for spent fuel storage cask submittals.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Procedures for spent fuel storage cask submittals. 72.230 Section 72.230 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.56 - Application for amendment of license.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Application for amendment of license. 72.56 Section 72.56 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE...

10 CFR 72.42 - Duration of license; renewal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Duration of license; renewal. 72.42 Section 72.42 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Issuance and...

10 CFR 72.62 - Backfitting.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Backfitting. 72.62 Section 72.62 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Issuance and Conditions of License § 72.62...

10 CFR 72.84 - Violations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Violations. 72.84 Section 72.84 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL... violation of the provisions of— (1) The Atomic Energy Act of 1954, as amended; (2) Title II of the Energy...

10 CFR 72.40 - Issuance of license.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Issuance of license. 72.40 Section 72.40 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Issuance and Conditions of...

10 CFR 72.16 - Filing of application for specific license.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Filing of application for specific license. 72.16 Section 72.16 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.244 - Application for amendment of a certificate of compliance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Application for amendment of a certificate of compliance. 72.244 Section 72.244 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN...

10 CFR 72.240 - Conditions for spent fuel storage cask reapproval.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Conditions for spent fuel storage cask reapproval. 72.240 Section 72.240 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.238 - Issuance of an NRC Certificate of Compliance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Issuance of an NRC Certificate of Compliance. 72.238 Section 72.238 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C...

10 CFR 72.58 - Issuance of amendment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Issuance of amendment. 72.58 Section 72.58 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE Issuance and Conditions of...

10 CFR 72.216 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false [Reserved] 72.216 Section 72.216 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General License for Storage of Spent Fuel at...

10 CFR 72.22 - Contents of application: General and financial information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Contents of application: General and financial information. 72.22 Section 72.22 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN...

10 CFR 63.303 - Implementation of Subpart L.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Implementation of Subpart L. 63.303 Section 63.303 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Implementation of Subpart L. (a) Compliance is based upon the arithmetic mean of the projected doses from DOE's...

7 CFR 170.12 - What are the selection criteria for participation in the USDA Farmers Market?

Code of Federal Regulations, 2010 CFR

2010-01-01

... referred to the Internal Revenue Service or a tax advisor. Receipts for donated foods may be obtained from... Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices... Farmers Market? The selection criteria are designed to ensure a consistently high level of quality and...

10 CFR 63.321 - Individual protection standard for human intrusion.

Code of Federal Regulations, 2011 CFR

2011-01-01

... determine the earliest time after disposal that the waste package would degrade sufficiently that a human... 10 Energy 2 2011-01-01 2011-01-01 false Individual protection standard for human intrusion. 63.321 Section 63.321 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES...

10 CFR 63.321 - Individual protection standard for human intrusion.

Code of Federal Regulations, 2013 CFR

2013-01-01

... determine the earliest time after disposal that the waste package would degrade sufficiently that a human... 10 Energy 2 2013-01-01 2013-01-01 false Individual protection standard for human intrusion. 63.321 Section 63.321 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES...

10 CFR 63.321 - Individual protection standard for human intrusion.

Code of Federal Regulations, 2010 CFR

2010-01-01

... determine the earliest time after disposal that the waste package would degrade sufficiently that a human... 10 Energy 2 2010-01-01 2010-01-01 false Individual protection standard for human intrusion. 63.321 Section 63.321 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES...

10 CFR 63.321 - Individual protection standard for human intrusion.

Code of Federal Regulations, 2014 CFR

2014-01-01

... determine the earliest time after disposal that the waste package would degrade sufficiently that a human... 10 Energy 2 2014-01-01 2014-01-01 false Individual protection standard for human intrusion. 63.321 Section 63.321 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES...

10 CFR 63.321 - Individual protection standard for human intrusion.

Code of Federal Regulations, 2012 CFR

2012-01-01

... determine the earliest time after disposal that the waste package would degrade sufficiently that a human... 10 Energy 2 2012-01-01 2012-01-01 false Individual protection standard for human intrusion. 63.321 Section 63.321 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES...

10 CFR 63.305 - Required characteristics of the reference biosphere.

Code of Federal Regulations, 2011 CFR

2011-01-01

....305 Section 63.305 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE... biosphere (other than climate), human biology, or increases or decreases of human knowledge or technology... factors remain constant as they are at the time of submission of the license application. (c) DOE must...

Pop Culture.

ERIC Educational Resources Information Center

Berger, Arthur Asa

Popular culture in America is comprehensively reviewed in this book. The book is designed for either high school or college level social studies or English courses and includes a variety of graphic illustrations that provide a thread of continuity throughout. Basically the author has developed a method of analysis that reveals how popular culture…

7 CFR 201.55a - Moisture and aeration of substratum.

Code of Federal Regulations, 2011 CFR

2011-01-01

... SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Germination Tests in the Administration of the Act § 201.55a Moisture.... Except as provided for those kinds of seeds requiring high moisture levels of the germination media, the...

7 CFR 201.55a - Moisture and aeration of substratum.

Code of Federal Regulations, 2010 CFR

2010-01-01

... SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Germination Tests in the Administration of the Act § 201.55a Moisture.... Except as provided for those kinds of seeds requiring high moisture levels of the germination media, the...

10 CFR 60.1 - Purpose and scope.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., in accordance with the Nuclear Waste Policy Act of 1992, as amended, and the Energy Policy Act of... 10 Energy 2 2013-01-01 2013-01-01 false Purpose and scope. 60.1 Section 60.1 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General...

10 CFR 60.7 - License not required for certain preliminary activities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false License not required for certain preliminary activities. 60.7 Section 60.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.7 License not required for certain preliminary...

10 CFR 60.1 - Purpose and scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., in accordance with the Nuclear Waste Policy Act of 1992, as amended, and the Energy Policy Act of... 10 Energy 2 2014-01-01 2014-01-01 false Purpose and scope. 60.1 Section 60.1 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General...

10 CFR 60.7 - License not required for certain preliminary activities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false License not required for certain preliminary activities. 60.7 Section 60.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.7 License not required for certain preliminary...

10 CFR 60.1 - Purpose and scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., in accordance with the Nuclear Waste Policy Act of 1992, as amended, and the Energy Policy Act of... 10 Energy 2 2011-01-01 2011-01-01 false Purpose and scope. 60.1 Section 60.1 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General...

Department of Energy National Laboratories A - L

Science.gov Websites

contributors to science and research. This high-level compilation of their history and achievements provides insights into their previous successes and continuing efforts. dropdown listing Ames Laboratory Our History The Ames Project (1942-1946) Ames Laboratory Hot Canyon A History of Innovation Points of Pride Recent

10 CFR 60.45 - Amendment of license.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Amendment of license. 60.45 Section 60.45 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses License Issuance and Amendment § 60.45 Amendment of license. (a) An application for amendment of a license...

10 CFR 60.42 - Conditions of license.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Conditions of license. 60.42 Section 60.42 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses License Issuance and Amendment § 60.42 Conditions of license. (a) A license issued pursuant to this part...

10 CFR 63.112 - Requirements for preclosure safety analysis of the geologic repository operations area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... geologic repository operations area. 63.112 Section 63.112 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Technical... repository operations area. The preclosure safety analysis of the geologic repository operations area must...

10 CFR 60.24 - Updating of application and environmental impact statement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Updating of application and environmental impact statement. 60.24 Section 60.24 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses License Applications § 60.24 Updating of application and...

10 CFR 63.111 - Performance objectives for the geologic repository operations area through permanent closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Performance objectives for the geologic repository... (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA... repository operations area through permanent closure. (a) Protection against radiation exposures and releases...

10 CFR 60.112 - Overall system performance objective for the geologic repository after permanent closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... repository after permanent closure. 60.112 Section 60.112 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Performance Objectives § 60.112 Overall system performance objective for the geologic repository after permanent closure...

10 CFR 60.132 - Additional design criteria for surface facilities in the geologic repository operations area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... geologic repository operations area. 60.132 Section 60.132 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Design Criteria for the Geologic Repository Operations Area § 60.132 Additional design criteria for surface facilities in...

10 CFR 63.203 - Implementation of Subpart K.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Implementation of Subpart K. 63.203 Section 63.203 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Implementation of Subpart K. DOE must demonstrate that normal operations at the Yucca Mountain site will and do...

10 CFR 63.203 - Implementation of Subpart K.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Implementation of Subpart K. 63.203 Section 63.203 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Implementation of Subpart K. DOE must demonstrate that normal operations at the Yucca Mountain site will and do...

10 CFR 63.203 - Implementation of Subpart K.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Implementation of Subpart K. 63.203 Section 63.203 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Implementation of Subpart K. DOE must demonstrate that normal operations at the Yucca Mountain site will and do...

10 CFR 63.202 - Definitions for Subpart K.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Definitions for Subpart K. 63.202 Section 63.202 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Definitions for Subpart K. General environment means everywhere outside the Yucca Mountain site, the Nellis...

10 CFR 63.203 - Implementation of Subpart K.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Implementation of Subpart K. 63.203 Section 63.203 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Implementation of Subpart K. DOE must demonstrate that normal operations at the Yucca Mountain site will and do...

10 CFR 63.203 - Implementation of Subpart K.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Implementation of Subpart K. 63.203 Section 63.203 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Implementation of Subpart K. DOE must demonstrate that normal operations at the Yucca Mountain site will and do...

10 CFR 63.202 - Definitions for Subpart K.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Definitions for Subpart K. 63.202 Section 63.202 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Definitions for Subpart K. General environment means everywhere outside the Yucca Mountain site, the Nellis...

10 CFR 63.202 - Definitions for Subpart K.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Definitions for Subpart K. 63.202 Section 63.202 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Definitions for Subpart K. General environment means everywhere outside the Yucca Mountain site, the Nellis...

10 CFR 63.202 - Definitions for Subpart K.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Definitions for Subpart K. 63.202 Section 63.202 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Definitions for Subpart K. General environment means everywhere outside the Yucca Mountain site, the Nellis...

10 CFR 63.202 - Definitions for Subpart K.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Definitions for Subpart K. 63.202 Section 63.202 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC... Definitions for Subpart K. General environment means everywhere outside the Yucca Mountain site, the Nellis...

Perceived Cultural Competence Levels in Undergraduate Athletic Training Students

ERIC Educational Resources Information Center

Volberding, Jennifer L.

2013-01-01

Context: As the patient population continues to diversify, it is essential that athletic training students (ATSs) are educated to provide culturally competent care. This high-quality health care within the context of a patient's race, ethnicity, language, religious beliefs, or behaviors is a foundation of professional practice. Objective:…

10 CFR 63.10 - Completeness and accuracy of information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Completeness and accuracy of information. 63.10 Section 63.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A.... Notification must be provided to the Director of Nuclear Material Safety and Safeguards, U.S. Nuclear...

10 CFR 60.10 - Completeness and accuracy of information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Completeness and accuracy of information. 60.10 Section 60.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN... provided to the Administrator of the appropriate Regional Office within two working days of identifying the...

Alabama District Improves by Sharpening Data and Goals

ERIC Educational Resources Information Center

Newman, Jane L.

2006-01-01

When students already are achieving at high levels, it can be easy for teachers to become complacent. However, Mountain Brook Schools in suburban Birmingham, Alabama, has developed a culture committed to continuous improvement that has resulted in an excellent system becoming outstanding. The key is professional development. Professional learning…

10 CFR 60.10 - Completeness and accuracy of information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Completeness and accuracy of information. 60.10 Section 60.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN... provided to the Administrator of the appropriate Regional Office within two working days of identifying the...

10 CFR 60.10 - Completeness and accuracy of information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Completeness and accuracy of information. 60.10 Section 60.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN... provided to the Administrator of the appropriate Regional Office within two working days of identifying the...

10 CFR 63.10 - Completeness and accuracy of information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Completeness and accuracy of information. 63.10 Section 63.10 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A.... Notification must be provided to the Director of Nuclear Material Safety and Safeguards, U.S. Nuclear...