40 CFR Appendix to Part 30 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-07-01

... NON-PROFIT ORGANIZATIONS Pt. 30, App. Appendix to Part 30—Contract Provisions All contracts awarded by a recipient, including small purchases, shall contain the following provisions as applicable: 1... unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of supplies or materials...

36 CFR Appendix A to Part 1210 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-07-01

... EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 1210, App. A Appendix A to Part 1210—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

24 CFR Appendix A to Part 84 - Contract Provisions

Code of Federal Regulations, 2010 CFR

2010-04-01

... EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 84, App. A Appendix A to Part 84—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following... which are unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of...

41 CFR Appendix A to Part 105 - 72-Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-01-01

..., HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 105-72, App. A Appendix A to Part 105-72—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

7 CFR Appendix A to Part 3019 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-01-01

... HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 3019, App. A Appendix A to Part 3019—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

15 CFR Appendix A to Part 14 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-01-01

... COMMERCIAL ORGANIZATIONS Pt. 14, App. A Appendix A to Part 14—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following provisions as applicable: 1. Equal... dangerous. These requirements do not apply to the purchases of supplies or materials or articles ordinarily...

24 CFR Appendix A to Part 84 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-04-01

... EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 84, App. A Appendix A to Part 84—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following... which are unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of...

34 CFR Appendix A to Part 74 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-07-01

... INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 74, App. A Appendix A to Part 74—Contract Provisions All contracts, awarded by a recipient including small purchases, shall... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

22 CFR Appendix A to Part 226 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-04-01

...-GOVERNMENTAL ORGANIZATIONS Pt. 226, App. A Appendix A to Part 226—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following provisions as applicable: 1... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

48 CFR 19.502-2 - Total small business set-asides.

Code of Federal Regulations, 2010 CFR

2010-10-01

... purchases on an unrestricted basis, the contracting officer shall include in the contract file the reason for this unrestricted purchase. If the contracting officer receives only one acceptable offer from a... important, it is not the only factor to be considered in determining whether a reasonable expectation exists...

10 CFR Appendix A to Subpart B of... - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-01-01

..., Hospitals, and Other Nonprofit Organizations Pt. 600, Subpt. B, App. A Appendix A to Subpart B of Part 600—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

43 CFR Appendix A to Subpart F of... - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-10-01

... Organizations Pt. 12, Subpt. F, App. A Appendix A to Subpart F of Part 12—Contract Provisions All contracts awarded by a recipient, including small purchases, shall contain the following provisions as applicable: 1... which are unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of...

43 CFR Appendix A to Subpart F of... - Contract Provisions

Code of Federal Regulations, 2010 CFR

2010-10-01

... Organizations Pt. 12, Subpt. F, App. A Appendix A to Subpart F of Part 12—Contract Provisions All contracts awarded by a recipient, including small purchases, shall contain the following provisions as applicable: 1... which are unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of...

48 CFR 19.308 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Determination of Small Business Status for Small... at 52.219-22, Small Disadvantaged Business Status, in solicitations that include the clause at 52.219..., Small Disadvantaged Business Participation Program—Disadvantaged Status and Reporting. Use the provision...

Contract Financing for Small Business

DTIC Science & Technology

1981-11-01

problem. Small business contractors devote considerable management attention to operating capital and cash flow. Small business contractors are keenly...CONTRACT FINANCING 0FOR SMALL BUSINESS November 1981 -s Paul R. McClenon Prepared pursuant to Department of Defense Contract No. MDA903-81-C-0166...34 i 12 17046 DistIbufios Unlimted !I CONTRACT FINANCING FOR SMALL BUSINESS EXECUTIVE SUMMHARY To perform effectively on a contract, a firm needs

48 CFR 19.708 - Contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting Program 19.708 Contract clauses. (a) Insert the clause at 52.219-8, Utilization of Small Business Concerns, in solicitations and contracts... clause at 52.219-9, Small Business Subcontracting Plan, in solicitations and contracts that offer...

48 CFR 19.708 - Contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting Program 19.708 Contract clauses. (a) Insert the clause at 52.219-8, Utilization of Small Business Concerns, in solicitations and contracts... clause at 52.219-9, Small Business Subcontracting Plan, in solicitations and contracts that offer...

48 CFR 19.708 - Contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting Program 19.708 Contract clauses. (a) Insert the clause at 52.219-8, Utilization of Small Business Concerns, in solicitations and contracts... clause at 52.219-9, Small Business Subcontracting Plan, in solicitations and contracts that offer...

48 CFR 19.708 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting Program 19.708 Contract clauses. (a) Insert the clause at 52.219-8, Utilization of Small Business Concerns, in solicitations and contracts... clause at 52.219-9, Small Business Subcontracting Plan, in solicitations and contracts that offer...

48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2013 CFR

2013-10-01

... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled...-disabled veteran-owned small business concerns; (2) The anticipated award price of the contract, including...

48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2014 CFR

2014-10-01

... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled...-disabled veteran-owned small business concerns; (2) The anticipated award price of the contract, including...

48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2012 CFR

2012-10-01

... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled...-disabled veteran-owned small business concerns; (2) The anticipated award price of the contract, including...

13 CFR 124.504 - What circumstances limit SBA's ability to accept a procurement for award as an 8(a) contract?

Code of Federal Regulations, 2014 CFR

2014-01-01

... solicitation for or otherwise expressed publicly a clear intent to award the contract as a small business set... include consideration of whether rejection of the requirement would seriously reduce the pool of similar...

48 CFR 319.270-1 - Solicitation provision and contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Solicitation provision and contract clause. 319.270-1 Section 319.270-1 Federal Acquisition Regulations System HEALTH AND HUMAN... Program, in solicitations that include the clause in FAR 52.219-9, Small Business Subcontracting Plan. The...

48 CFR 319.270-1 - Solicitation provision and contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Solicitation provision and contract clause. 319.270-1 Section 319.270-1 Federal Acquisition Regulations System HEALTH AND HUMAN... Program, in solicitations that include the clause in FAR 52.219-9, Small Business Subcontracting Plan. The...

76 FR 55849 - Federal Acquisition Regulation; Constitutionality of Federal Contracting Programs for Minority...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-09

... disadvantaged business (including Alaska Native Corporations and Indian tribes), and women- owned small business... for Minority-Owned and Other Small Businesses AGENCY: Department of Defense (DoD), General Services... Force (USAF) on small disadvantaged business concerns and certain institutions of higher education...

Survey of Small Business Barriers to Department of Defense Contracts

DTIC Science & Technology

2017-01-01

Survey of SMALL BUSINESS BARRIERS to DEPARTMENT of DEFENSE CONTRACTS Ronnie Schilling, Thomas A. Mazzuchi, and Shahram Sarkani A key tenet of...success in retaining small businesses and meeting small business contracting goals. Results of a survey given to 681 small business leaders show many...2017, Vol. 24 No. 1 : 2–29 Survey of Small Business Barriers to DoD Contracts http://www.dau.mil Creating more than half of this country’s gross

Local small airway epithelial injury induces global smooth muscle contraction and airway constriction

PubMed Central

Zhou, Jian; Alvarez-Elizondo, Martha B.; Botvinick, Elliot

2012-01-01

Small airway epithelial cells form a continuous sheet lining the conducting airways, which serves many functions including a physical barrier to protect the underlying tissue. In asthma, injury to epithelial cells can occur during bronchoconstriction, which may exacerbate airway hyperreactivity. To investigate the role of epithelial cell rupture in airway constriction, laser ablation was used to precisely rupture individual airway epithelial cells of small airways (<300-μm diameter) in rat lung slices (∼250-μm thick). Laser ablation of single epithelial cells using a femtosecond laser reproducibly induced airway contraction to ∼70% of the original cross-sectional area within several seconds, and the contraction lasted for up to 40 s. The airway constriction could be mimicked by mechanical rupture of a single epithelial cell using a sharp glass micropipette but not with a blunt glass pipette. These results suggest that soluble mediators released from the wounded epithelial cell induce global airway contraction. To confirm this hypothesis, the lysate of primary human small airway epithelial cells stimulated a similar airway contraction. Laser ablation of single epithelial cells triggered a single instantaneous Ca2+ wave in the epithelium, and multiple Ca2+ waves in smooth muscle cells, which were delayed by several seconds. Removal of extracellular Ca2+ or decreasing intracellular Ca2+ both blocked laser-induced airway contraction. We conclude that local epithelial cell rupture induces rapid and global airway constriction through release of soluble mediators and subsequent Ca2+-dependent smooth muscle shortening. PMID:22114176

Local small airway epithelial injury induces global smooth muscle contraction and airway constriction.

PubMed

Zhou, Jian; Alvarez-Elizondo, Martha B; Botvinick, Elliot; George, Steven C

2012-02-01

Small airway epithelial cells form a continuous sheet lining the conducting airways, which serves many functions including a physical barrier to protect the underlying tissue. In asthma, injury to epithelial cells can occur during bronchoconstriction, which may exacerbate airway hyperreactivity. To investigate the role of epithelial cell rupture in airway constriction, laser ablation was used to precisely rupture individual airway epithelial cells of small airways (<300-μm diameter) in rat lung slices (∼250-μm thick). Laser ablation of single epithelial cells using a femtosecond laser reproducibly induced airway contraction to ∼70% of the original cross-sectional area within several seconds, and the contraction lasted for up to 40 s. The airway constriction could be mimicked by mechanical rupture of a single epithelial cell using a sharp glass micropipette but not with a blunt glass pipette. These results suggest that soluble mediators released from the wounded epithelial cell induce global airway contraction. To confirm this hypothesis, the lysate of primary human small airway epithelial cells stimulated a similar airway contraction. Laser ablation of single epithelial cells triggered a single instantaneous Ca(2+) wave in the epithelium, and multiple Ca(2+) waves in smooth muscle cells, which were delayed by several seconds. Removal of extracellular Ca(2+) or decreasing intracellular Ca(2+) both blocked laser-induced airway contraction. We conclude that local epithelial cell rupture induces rapid and global airway constriction through release of soluble mediators and subsequent Ca(2+)-dependent smooth muscle shortening.

3 CFR - Establishing an Interagency Task Force on Federal Contracting Opportunities for Small Businesses

Code of Federal Regulations, 2011 CFR

2011-01-01

..., including businesses owned by women, minorities, socially and economically disadvantaged individuals, and... Underutilized Business Zones (at least 3 percent) or that are owned by women (at least 5 percent), socially and... contracts—more work can and should be done. I am committed to ensuring that small businesses, including...

48 CFR 1819.7103 - Solicitation provision and contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... AND SPACE ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Rural Area Small Business Plan 1819.7103 Solicitation provision and contract clause. The contracting officer shall insert the clause at 1852.219-74, Use of Rural Area Small Businesses, in solicitations and contracts that offer...

22 CFR Appendix A to Part 145 - Clauses for Contracts and Small Purchases Awarded by Recipient

Code of Federal Regulations, 2011 CFR

2011-04-01

.... 145, App. A Appendix A to Part 145—Clauses for Contracts and Small Purchases Awarded by Recipient All contracts and small purchases, awarded by a recipient who is subject to this regulation, shall contain the... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Clauses for Contracts and Small Purchases...

48 CFR 42.1601 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42.1601 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Small Business Contract Administration 42.1601 General. The... request to the contracting officer from a small business concern with respect to a contract administration...

The Effectiveness of United States Coast Guard Participation in the Department of Transportation 8(a) Pilot Program.

DTIC Science & Technology

1987-06-01

Paul J. Seidman, "An Overview of Small and Disadvantaged Business Contracting," National Contract Management Journal 18 (Summer 1985): 5-19. 4. 49...Overview of Small and Disadvantaged Business Contracting," National Contract Management Journal, 18 (Summer 1985): 5-19. 6. National Archives and Records...J. Seidman, "An Overview of Small and Disadvantaged Business Contracting," National Contract Management Journal 18 (Summer 1985): 5-19. 9. 15 United

76 FR 68032 - Federal Acquisition Regulation; Set-Asides for Small Business

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-02

... clause 52.219-29, Notice of Set-Aside for Economically Disadvantaged Women-owned Small Business Concerns... disadvantaged women-owned small business (EDWOSB) concerns under 19.1505(b). This includes multiple-award...). (b) The contracting officer shall insert the clause 52.219-30, Notice of Set-Aside for Women-Owned...

48 CFR 37.108 - Small business Certificate of Competency.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Small business Certificate... proposal and a resultant technical evaluation and source selection, the small business Certificate of... REGULATION SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Service Contracts-General 37.108 Small...

48 CFR 37.108 - Small business Certificate of Competency.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Small business Certificate... proposal and a resultant technical evaluation and source selection, the small business Certificate of... REGULATION SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Service Contracts-General 37.108 Small...

48 CFR 37.108 - Small business Certificate of Competency.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Small business Certificate... proposal and a resultant technical evaluation and source selection, the small business Certificate of... REGULATION SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Service Contracts-General 37.108 Small...

48 CFR 37.108 - Small business Certificate of Competency.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Small business Certificate... proposal and a resultant technical evaluation and source selection, the small business Certificate of... REGULATION SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Service Contracts-General 37.108 Small...

13 CFR 127.503 - When is a contracting officer authorized to restrict competition under this part?

Code of Federal Regulations, 2014 CFR

2014-01-01

... SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT PROGRAM Federal Contract..., anticipated award price, and the acquisition history, will be considered in making a decision as to which... orders issued pursuant to the contract, from that point forward, towards its women-owned small business...

48 CFR 44.202-2 - Considerations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... contract requirements regarding— (i) Small business subcontracting, including, if applicable, its plan for...-owned small business concerns (see part 19); and (ii) Purchase from nonprofit agencies designated by the... officer responsible for consent must, at a minimum, review the request and supporting data and consider...

48 CFR 215.203-70 - Requests for proposals-tiered evaluation of offers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY... shall be consistent with FAR part 19. (b) Consideration shall be given to the tiers of small businesses (e.g., 8(a), HUBZone small business, service-disabled veteran-owned small business, small business...

48 CFR 252.219-7003 - Small business subcontracting plan (DoD contracts).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Small business... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.219-7003 Small business subcontracting plan (DoD contracts). As prescribed in 219.708(b)(1)(A), use the following clause: Small Business...

49 CFR 22.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Disadvantaged Business (SDB); Section 8(a) Program participant; HUBZONE Empowerment Contracting Program; and... DOT OSDBU. Small and disadvantaged business (SDB) includes 8(a); small disadvantaged business; women... provided by the Participating Lender to the DBE or SDB that will enable the DBE or SDB to become more...

49 CFR 22.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Disadvantaged Business (SDB); Section 8(a) Program participant; HUBZONE Empowerment Contracting Program; and... DOT OSDBU. Small and disadvantaged business (SDB) includes 8(a); small disadvantaged business; women... provided by the Participating Lender to the DBE or SDB that will enable the DBE or SDB to become more...

49 CFR 22.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Disadvantaged Business (SDB); Section 8(a) Program participant; HUBZONE Empowerment Contracting Program; and... DOT OSDBU. Small and disadvantaged business (SDB) includes 8(a); small disadvantaged business; women... provided by the Participating Lender to the DBE or SDB that will enable the DBE or SDB to become more...

49 CFR 22.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Disadvantaged Business (SDB); Section 8(a) Program participant; HUBZONE Empowerment Contracting Program; and... DOT OSDBU. Small and disadvantaged business (SDB) includes 8(a); small disadvantaged business; women... provided by the Participating Lender to the DBE or SDB that will enable the DBE or SDB to become more...

49 CFR 22.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Disadvantaged Business (SDB); Section 8(a) Program participant; HUBZONE Empowerment Contracting Program; and... DOT OSDBU. Small and disadvantaged business (SDB) includes 8(a); small disadvantaged business; women... provided by the Participating Lender to the DBE or SDB that will enable the DBE or SDB to become more...

A review of mixing and propulsion of chyme in the small intestine: fresh insights from new methods.

PubMed

Lentle, R G; de Loubens, C

2015-05-01

The small intestine is a convoluted flexible tube of inconstant form and capacity through which chyme is propelled and mixed by varying patterns of contraction. These inconstancies have prevented quantitative comparisons of the manner in which contractile activity engenders mixing of contained chyme. Recent quantitative work based on spatiotemporal mapping of intestinal contractions, macro- and micro-rheology, particle image velocimetry and real-time modelling has provided new insights into this process. Evidence indicates that the speeds and patterns of the various types of small intestinal contraction are insufficient to secure optimal mixing and enzymatic digestion over a minimal length of intestine. Hence particulate substrates and soluble nutrients become dispersed along the length of the lumen. Mixing within the lumen is not turbulent but results from localised folding and kneading of the contents by contractions but is augmented by the inconstant spatial disposition of the contractions and their component contractile processes. The latter include inconstancies in the sites of commencement and the directions of propagation of contraction in component groups of smooth muscle cells and in the coordination of the radial and circular components of smooth muscle contraction. Evidence suggests there is ongoing augmentation of mixing at the periphery of the lumen, during both the post-prandial and inter-meal periods, to promote flow around and between adjacent villi. This results largely from folding of the relatively inelastic mucosa during repeated radial and longitudinal muscular contraction, causing chyme to be displaced by periodic crowding and separation of the tips of the relatively rigid villi. Further, micro-rheological studies indicate that such peripheral mixing may extend to the apices of enterocytes owing to discontinuities in the mobile mucus layer that covers the ileal mucosa.

76 FR 26948 - Small Business Jobs Act Tour: Selected Provisions Having an Effect on Government Contracting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-10

...] Small Business Jobs Act Tour: Selected Provisions Having an Effect on Government Contracting AGENCY: U.S... series of public meetings on the implementation of provisions of the Small Business Jobs Act of 2010... INFORMATION CONTACT: Richard L. Miller, Small Business Job's Act Tour-Office of Government Contracting and...

48 CFR 3019.708-70 - Solicitation provision and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HOMELAND SECURITY, HOMELAND SECURITY ACQUISITION REGULATION (HSAR) SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting Program 3019.708-70 Solicitation provision and contract clauses. (a) The contracting officer shall insert the clause at (HSAR) 48 CFR 3052.219-70, Small Business...

10 CFR 600.7 - Small and disadvantaged and women-owned business participation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... encourages the participation in financial assistance awards of small businesses, including those owned by... of Federal Procurement Policy. (c) When entering into contracts under financial assistance awards, recipients and subrecipients shall comply with the requirements of §§ 600.144, 600.236 and 600.331, as...

10 CFR 600.7 - Small and disadvantaged and women-owned business participation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... encourages the participation in financial assistance awards of small businesses, including those owned by... of Federal Procurement Policy. (c) When entering into contracts under financial assistance awards, recipients and subrecipients shall comply with the requirements of §§ 600.144, 600.236 and 600.331, as...

10 CFR 600.7 - Small and disadvantaged and women-owned business participation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... encourages the participation in financial assistance awards of small businesses, including those owned by... of Federal Procurement Policy. (c) When entering into contracts under financial assistance awards, recipients and subrecipients shall comply with the requirements of §§ 600.144, 600.236 and 600.331, as...

10 CFR 600.7 - Small and disadvantaged and women-owned business participation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... encourages the participation in financial assistance awards of small businesses, including those owned by... of Federal Procurement Policy. (c) When entering into contracts under financial assistance awards, recipients and subrecipients shall comply with the requirements of §§ 600.144, 600.236 and 600.331, as...

78 FR 60174 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-70; Small Entity Compliance Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

... DEPARTMENT OF DEFENSE GENERAL SERVICES ADMINISTRATION NATIONAL AERONAUTICS AND SPACE... Acquisition Circular 2005-70; Small Entity Compliance Guide AGENCY: Department of Defense (DoD), General... employees at subpart 3.9. In accordance with FAR 1.108(d)(3), contracting officers are encouraged to include...

48 CFR 19.807 - Estimating the fair market price.

Code of Federal Regulations, 2014 CFR

2014-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a..., available in-house cost estimates, data (including certified cost or pricing data) submitted by the SBA or the 8(a) contractor, and data obtained from any other Government agency. (c) In estimating a fair...

48 CFR 19.807 - Estimating the fair market price.

Code of Federal Regulations, 2012 CFR

2012-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a..., available in-house cost estimates, data (including certified cost or pricing data) submitted by the SBA or the 8(a) contractor, and data obtained from any other Government agency. (c) In estimating a fair...

48 CFR 19.807 - Estimating the fair market price.

Code of Federal Regulations, 2013 CFR

2013-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a..., available in-house cost estimates, data (including certified cost or pricing data) submitted by the SBA or the 8(a) contractor, and data obtained from any other Government agency. (c) In estimating a fair...

48 CFR 19.807 - Estimating the fair market price.

Code of Federal Regulations, 2011 CFR

2011-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a..., available in-house cost estimates, data (including certified cost or pricing data) submitted by the SBA or the 8(a) contractor, and data obtained from any other Government agency. (c) In estimating a fair...

48 CFR 19.807 - Estimating the fair market price.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a..., available in-house cost estimates, data (including certified cost or pricing data) submitted by the SBA or the 8(a) contractor, and data obtained from any other Government agency. (c) In estimating a fair...

13 CFR 125.2 - Prime contracting assistance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Prime contracting assistance. 125.2 Section 125.2 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS § 125.2 Prime contracting assistance. (a) General. Small business concerns must receive any award...

48 CFR 1832.412 - Contract clause. (NASA supplement paragraphs (e) and (f))

Code of Federal Regulations, 2014 CFR

2014-10-01

... AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Advance Payments for... the Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) programs...

48 CFR 1832.412 - Contract clause. (NASA supplement paragraphs (e) and (f))

Code of Federal Regulations, 2011 CFR

2011-10-01

... AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Advance Payments for... the Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) programs...

48 CFR 1832.412 - Contract clause. (NASA supplement paragraphs (e) and (f))

Code of Federal Regulations, 2010 CFR

2010-10-01

... AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Advance Payments for... the Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) programs...

48 CFR 1832.412 - Contract clause. (NASA supplement paragraphs (e) and (f))

Code of Federal Regulations, 2012 CFR

2012-10-01

... AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Advance Payments for... the Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) programs...

48 CFR 1832.412 - Contract clause. (NASA supplement paragraphs (e) and (f))

Code of Federal Regulations, 2013 CFR

2013-10-01

... AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Advance Payments for... the Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) programs...

48 CFR 32.104 - Providing contract financing.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Providing contract financing. (a) Prudent contract financing can be a useful working tool in Government...) If the contractor is a small business concern, the contracting officer must give special attention to... competency from the Small Business Administration has no bearing on the contractor's need for or entitlement...

48 CFR 1832.501-1 - Customary progress payment rates. (NASA supplements paragraph (a))

Code of Federal Regulations, 2012 CFR

2012-10-01

... System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING... II contracts in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer...

48 CFR 1832.501-1 - Customary progress payment rates. (NASA supplements paragraph (a))

Code of Federal Regulations, 2014 CFR

2014-10-01

... System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING... II contracts in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer...

48 CFR 1832.501-1 - Customary progress payment rates. (NASA supplements paragraph (a))

Code of Federal Regulations, 2011 CFR

2011-10-01

... System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING... II contracts in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer...

48 CFR 1832.501-1 - Customary progress payment rates. (NASA supplements paragraph (a))

Code of Federal Regulations, 2013 CFR

2013-10-01

... System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING... II contracts in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer...

Air Force Needs Better Processes to Appropriately Justify and Manage Cost-Reimbursable Contracts

DTIC Science & Technology

2013-03-21

Contracts Reviewed 4 The Small Business Innovation Research Program 4 Review of Internal Controls 5 ...stimulate high-tech innovation, and increase private-sector commercialization. The SBIR 5 program was established under the Small Business...contracts valued at about $7.4 billion. 5 According to the Office of Federal Procurement Policy, a hybrid contract allows contracting officers to

48 CFR 52.219-25 - Small Disadvantaged Business Participation Program-Disadvantaged Status and Reporting.

Code of Federal Regulations, 2013 CFR

2013-10-01

... and is applicable if this contract contains small disadvantaged business (SDB) participation targets... requirement. If this contract contains SDB participation targets, the Contractor shall report on the participation of SDB concerns at contract completion, or as otherwise provided in this contract. Reporting may...

48 CFR 52.219-25 - Small Disadvantaged Business Participation Program-Disadvantaged Status and Reporting.

Code of Federal Regulations, 2014 CFR

2014-10-01

... and is applicable if this contract contains small disadvantaged business (SDB) participation targets... requirement. If this contract contains SDB participation targets, the Contractor shall report on the participation of SDB concerns at contract completion, or as otherwise provided in this contract. Reporting may...

48 CFR 18.114 - Contracting with the Small Business Administration (The 8(a) Program).

Code of Federal Regulations, 2011 CFR

2011-10-01

... Business Administration (The 8(a) Program). 18.114 Section 18.114 Federal Acquisition Regulations System... Acquisition Flexibilities 18.114 Contracting with the Small Business Administration (The 8(a) Program). Contracts may be awarded to the Small Business Administration (SBA) for performance by eligible 8(a) firms...

48 CFR 18.114 - Contracting with the Small Business Administration (The 8(a) Program).

Code of Federal Regulations, 2010 CFR

2010-10-01

... Business Administration (The 8(a) Program). 18.114 Section 18.114 Federal Acquisition Regulations System... Acquisition Flexibilities 18.114 Contracting with the Small Business Administration (The 8(a) Program). Contracts may be awarded to the Small Business Administration (SBA) for performance by eligible 8(a) firms...

KSC SBIR/STTR 2004 Program Year Report

NASA Technical Reports Server (NTRS)

2005-01-01

The Kennedy Space Center Level III SBIR/STTR management staff is under the Technology Transfer Office within the Spaceport Engineering and Technology Directorate. The SBIR and STTR programs provide an opportunity for small high technology companies and research institutions to participate in Government-sponsored research and development (R&D) programs in key technology areas. The SBIR program was established by Congress in 1982 to provide increased opportunities for small businesses to participate in R&D programs, increase employment, and improve U.S. competitiveness. The program's specific objectives are to stimulate U.S. technological innovation, use small businesses to meet Federal research and development needs, increase private sector commercialization of innovations, and foster and encourage participation by socially disadvantaged businesses. Legislation enacted in December 2000 reauthorized the program and strengthened emphasis on pursuing commercial applications of SBIR projects. An SBIR Phase I contract is the opportunity to establish the feasibility and technical merit of a proposed innovation. Selected competitively, the Phase I contract lasts for 6 months and is funded up to $70,000. SBIR Phase II contracts continue the most promising Phase I projects based on scientific! technical merit, expected value to NASA, company capability, and commercial potential. Phase II contracts are usually for a period of 24 months and may not exceed $600,000. NASA usually selects approximately 40 percent of Phase I projects to continue to the Phase II level. Phase III is the process of furthering the development of a product to make it commercially available. The STTR program awards contracts to small business concerns for cooperative R&D with a nonprofit research institution. Research institutions include nonprofit research organizations, Federal laboratories, or universities. The goal of the program established by Congress is to facilitate the transfer of technology developed by a research institution through the entrepreneurship of a small business. The STIR program is smaller in funding than the SBIR program. While the proposal is submitted by the small business concern, at least 30 percent of the funding and work must originate with the research institution. STTR Phase I projects receive up to $100K for a one-year effort, and a Phase II contract receives up to $600K for two years.

High pressure fiber optic sensor system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guida, Renato; Xia, Hua; Lee, Boon K

2013-11-26

The present application provides a fiber optic sensor system. The fiber optic sensor system may include a small diameter bellows, a large diameter bellows, and a fiber optic pressure sensor attached to the small diameter bellows. Contraction of the large diameter bellows under an applied pressure may cause the small diameter bellows to expand such that the fiber optic pressure sensor may measure the applied pressure.

A bill to require contractors to notify small business concerns that have been included in offers relating to contracts let by Federal agencies, and for other purposes.

THOMAS, 112th Congress

Sen. Casey, Robert P., Jr. [D-PA

2011-02-16

Senate - 02/16/2011 Read twice and referred to the Committee on Small Business and Entrepreneurship. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

48 CFR 619.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2014 CFR

2014-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS Contracting with the Small Business Administration (The 8(a) Program) 619... obtain certified cost or pricing data directly from the 8(a) contractor if the contract is being awarded...

48 CFR 619.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2012 CFR

2012-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS Contracting with the Small Business Administration (The 8(a) Program) 619... obtain certified cost or pricing data directly from the 8(a) contractor if the contract is being awarded...

48 CFR 619.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2013 CFR

2013-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS Contracting with the Small Business Administration (The 8(a) Program) 619... obtain certified cost or pricing data directly from the 8(a) contractor if the contract is being awarded...

48 CFR 219.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business... cited in 219.800— (1) The contracting officer shall obtain cost or pricing data from the 8(a) contractor...

48 CFR 619.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2011 CFR

2011-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS Contracting with the Small Business Administration (The 8(a) Program) 619... obtain certified cost or pricing data directly from the 8(a) contractor if the contract is being awarded...

48 CFR 219.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business... cited in 219.800— (1) The contracting officer shall obtain certified cost or pricing data from the 8(a...

48 CFR 219.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business... cited in 219.800— (1) The contracting officer shall obtain cost or pricing data from the 8(a) contractor...

48 CFR 219.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business... cited in 219.800— (1) The contracting officer shall obtain certified cost or pricing data from the 8(a...

Selection against small males in utero: a test of the Wells hypothesis.

PubMed

Catalano, R; Goodman, J; Margerison-Zilko, C E; Saxton, K B; Anderson, E; Epstein, M

2012-04-01

The argument that women in stressful environments spontaneously abort their least fit fetuses enjoys wide dissemination despite the fact that several of its most intuitive predictions remain untested. The literature includes no tests, for example, of the hypothesis that these mechanisms select against small for gestational age (SGA) males. We apply time-series modeling to 4.9 million California male term births to test the hypothesis that the rate of SGA infants in 1096 weekly birth cohorts varies inversely with labor market contraction, a known stressor of contemporary populations. We find support for the hypothesis that small size becomes less frequent among term male infants when the labor market contracts. Our findings contribute to the evidence supporting selection in utero. They also suggest that research into the association between maternal stress and adverse birth outcomes should acknowledge the possibility that fetal loss may affect findings and their interpretation. Strengths of our analyses include the large number and size of our birth cohorts and our control for autocorrelation. Weaknesses include that we, like nearly all researchers in the field, have no direct measure of fetal loss.

Imaging System

NASA Technical Reports Server (NTRS)

1995-01-01

The 1100C Virtual Window is based on technology developed under NASA Small Business Innovation (SBIR) contracts to Ames Research Center. For example, under one contract Dimension Technologies, Inc. developed a large autostereoscopic display for scientific visualization applications. The Virtual Window employs an innovative illumination system to deliver the depth and color of true 3D imaging. Its applications include surgery and Magnetic Resonance Imaging scans, viewing for teleoperated robots, training, and in aviation cockpit displays.

78 FR 37692 - Federal Acquisition Regulation; Contracting With Women-Owned Small Business Concerns

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-21

...-AM59 Federal Acquisition Regulation; Contracting With Women-Owned Small Business Concerns AGENCY... disadvantaged women-owned small business concerns and to women-owned small business concerns eligible under the... for [[Page 37693

48 CFR 15.604 - Agency points of contact.

Code of Federal Regulations, 2010 CFR

2010-10-01

... agency: upcoming solicitations; Broad Agency Announcements; Small Business Innovation Research programs; Small Business Technology Transfer Research programs; Program Research and Development Announcements; or... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 15.604 Agency points...

Effects of Dai-kenchu-to on spontaneous activity in the mouse small intestine.

PubMed

Kito, Yoshihiko; Suzuki, Hikaru

2006-12-01

The effects of Dai-kenchu-to (DKT), a Chinese medicine, on spontaneous activity of mouse small intestine were investigated. Experiments were carried out with tension recording and intracellular recording. DKT contracted mouse longitudinal smooth muscles in a dose dependent manner (0.1-10 mg/ml). Low concentration of DKT (0.1 mg/ml) did not contract the longitudinal muscles of mouse small intestine. DKT (0.1 mg/ml) inhibited contraction elicited by transmural nerve stimulation (TNS). DKT (1 mg/ml) evoked relaxation before contraction. The initial relaxation was abolished by Nomega-nitro-L-arginine (L-NNA). DKT (10 mg/ml)-induced contraction had two components: a transient rapid contraction and a following slow contraction. Atropine inhibited DKT (1 mg/ml)-induced contraction to about 50% of control. In the presence of atropine, tetrodotoxin (TTX) inhibited the contraction elicited by DKT (1 mg/ml) to about 80%. DKT depolarized the membrane and decreased the amplitude of pacemaker potentials recorded from in situ myenteric interstitial cells of Cajal (ICC-MY) with no alteration to the frequency, duration and maximum rates of rise in the presence of nifedipine and TTX. The same results were obtained in slow waves recorded from circular smooth muscle cells. These results indicate that DKT evoked both contraction and relaxation by releasing acetylcholine, nitric oxide and other excitatory neurotransmitters in mouse small intestine. DKT had no effects on pacemaker mechanisms and electrical coupling between ICC-MY and smooth muscle cells in mouse small intestine. The results also suggest that DKT may contract smooth muscles by depolarizing the membrane directly.

Phase Zero Contracting Operations-Strategic and Integrative Planning for Contingency and Expeditionary Operations

DTIC Science & Technology

2013-10-01

349–372 Phase Zero Contracting Operations (PZCO) FIGURE 4. CONTRACTING PHASE ZERO: PLAN, EXERCISE, REHEARSE, AND SYNCHRONIZE Note. BPA = Blanket...More Robust Construction Supplies; Oce Equipment; Quality of Life; and Morale, Welfare, and Recreation PO/TO/DO/ BPA Small Purchase Standard Vehicles PO...TO/DO/ BPA Small Purchase Standard Vehicles PO/TO/DO/ BPA Small Purchase Standard Vehicles PO/TO/DO/ BPA Small Purchase Food, Water, Billeting, Hygiene

48 CFR 519.7017 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7017 Contract clauses. (a) The contracting officer shall insert the clause at 552.219-75, GSA Mentor-Protégé Program, in all unrestricted... small business protégé. (b) The contracting officer shall insert the clause at 552.219-76, Mentor...

76 FR 43571 - Small Business HUBZone Program; Government Contracting Programs

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

... SMALL BUSINESS ADMINISTRATION 13 CFR Part 126 RIN 3245-AG45 Small Business HUBZone Program; Government Contracting Programs AGENCY: U.S. Small Business Administration. ACTION: Interim final rule with request for comments. SUMMARY: This interim final rule amends the U.S. Small Business Administration's...

22 CFR Appendix A to Part 145 - Clauses for Contracts and Small Purchases Awarded by Recipient

Code of Federal Regulations, 2014 CFR

2014-04-01

... Awarded by Recipient A Appendix A to Part 145 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS.... 145, App. A Appendix A to Part 145—Clauses for Contracts and Small Purchases Awarded by Recipient All contracts and small purchases, awarded by a recipient who is subject to this regulation, shall contain the...

22 CFR Appendix A to Part 145 - Clauses for Contracts and Small Purchases Awarded by Recipient

Code of Federal Regulations, 2013 CFR

2013-04-01

... Awarded by Recipient A Appendix A to Part 145 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS.... 145, App. A Appendix A to Part 145—Clauses for Contracts and Small Purchases Awarded by Recipient All contracts and small purchases, awarded by a recipient who is subject to this regulation, shall contain the...

22 CFR Appendix A to Part 145 - Clauses for Contracts and Small Purchases Awarded by Recipient

Code of Federal Regulations, 2012 CFR

2012-04-01

... Awarded by Recipient A Appendix A to Part 145 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS.... 145, App. A Appendix A to Part 145—Clauses for Contracts and Small Purchases Awarded by Recipient All contracts and small purchases, awarded by a recipient who is subject to this regulation, shall contain the...

48 CFR 1827.304-1 - General. (NASA supplements paragraphs (a), (b), (c), (f), (g), and (h))

Code of Federal Regulations, 2011 CFR

2011-10-01

..., shall apply. (b) Greater rights determinations. In any contract with other than a small business firm or... in the performance of work under any contract with other than a small business firm or a nonprofit... inventions made and reported under any contract with other than a small business firm or a nonprofit...

48 CFR 1827.304-1 - General. (NASA supplements paragraphs (a), (b), (c), (f), (g), and (h))

Code of Federal Regulations, 2014 CFR

2014-10-01

..., shall apply. (b) Greater rights determinations. In any contract with other than a small business firm or... in the performance of work under any contract with other than a small business firm or a nonprofit... inventions made and reported under any contract with other than a small business firm or a nonprofit...

48 CFR 1827.304-1 - General. (NASA supplements paragraphs (a), (b), (c), (f), (g), and (h))

Code of Federal Regulations, 2010 CFR

2010-10-01

..., shall apply. (b) Greater rights determinations. In any contract with other than a small business firm or... in the performance of work under any contract with other than a small business firm or a nonprofit... inventions made and reported under any contract with other than a small business firm or a nonprofit...

48 CFR 1827.304-1 - General. (NASA supplements paragraphs (a), (b), (c), (f), (g), and (h))

Code of Federal Regulations, 2013 CFR

2013-10-01

..., shall apply. (b) Greater rights determinations. In any contract with other than a small business firm or... in the performance of work under any contract with other than a small business firm or a nonprofit... inventions made and reported under any contract with other than a small business firm or a nonprofit...

48 CFR 1827.304-1 - General. (NASA supplements paragraphs (a), (b), (c), (f), (g), and (h))

Code of Federal Regulations, 2012 CFR

2012-10-01

..., shall apply. (b) Greater rights determinations. In any contract with other than a small business firm or... in the performance of work under any contract with other than a small business firm or a nonprofit... inventions made and reported under any contract with other than a small business firm or a nonprofit...

48 CFR 1815.403-170 - Waivers of cost or pricing data.

Code of Federal Regulations, 2010 CFR

2010-10-01

... data when contracting for Small Business Innovation Research (SBIR) program Phase II contracts. However... SPACE ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing...

78 FR 26504 - Women-Owned Small Business Federal Contract Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-07

... SMALL BUSINESS ADMINISTRATION 13 CFR Part 127 RIN 3245-AG55 Women-Owned Small Business Federal Contract Program AGENCY: U.S. Small Business Administration. ACTION: Interim final rule. SUMMARY: The U.S. Small Business Administration (SBA) is amending its regulations to implement Section 1697 of the...

Small Business Innovations (Crystal Components)

NASA Technical Reports Server (NTRS)

1991-01-01

Scientific Materials Corporation, Bozeman, MT developed the SciMax line of improved Nd:Yag crystals under an Small Business Innovation Research (SBIR) contract with Langley Research Center. They reduced the amount of water trapped in the crystals during growth to improve the optical quality and efficiency. Applications of the crystals include fiber optics, telecommunications, welding, drilling, eye surgery and medical instrumentation.

13 CFR 127.507 - Are there EDWOSB and WOSB contracting opportunities at or below the simplified acquisition...

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Are there EDWOSB and WOSB contracting opportunities at or below the simplified acquisition threshold? 127.507 Section 127.507 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT PROGRAM Federal Contract Assistance § 127.507 Are...

13 CFR 127.507 - Are there EDWOSB and WOSB contracting opportunities at or below the simplified acquisition...

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Are there EDWOSB and WOSB contracting opportunities at or below the simplified acquisition threshold? 127.507 Section 127.507 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT PROGRAM Federal Contract Assistance § 127.507 Are...

NASA technology utilization program: The small business market

NASA Technical Reports Server (NTRS)

Vannoy, J. K.; Garcia-Otero, F.; Johnson, F. D.; Staskin, E.

1980-01-01

Technology transfer programs were studied to determine how they might be more useful to the small business community. The status, needs, and technology use patterns of small firms are reported. Small business problems and failures are considered. Innovation, capitalization, R and D, and market share problems are discussed. Pocket, captive, and new markets are summarized. Small manufacturers and technology acquisition are discussed, covering external and internal sources, and NASA technology. Small business and the technology utilization program are discussed, covering publications and industrial applications centers. Observations and recommendations include small business market development and contracting, and NASA management technology.

Optimizing Tensor Contraction Expressions for Hybrid CPU-GPU Execution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ma, Wenjing; Krishnamoorthy, Sriram; Villa, Oreste

2013-03-01

Tensor contractions are generalized multidimensional matrix multiplication operations that widely occur in quantum chemistry. Efficient execution of tensor contractions on Graphics Processing Units (GPUs) requires several challenges to be addressed, including index permutation and small dimension-sizes reducing thread block utilization. Moreover, to apply the same optimizations to various expressions, we need a code generation tool. In this paper, we present our approach to automatically generate CUDA code to execute tensor contractions on GPUs, including management of data movement between CPU and GPU. To evaluate our tool, GPU-enabled code is generated for the most expensive contractions in CCSD(T), a key coupledmore » cluster method, and incorporated into NWChem, a popular computational chemistry suite. For this method, we demonstrate speedup over a factor of 8.4 using one GPU (instead of one core per node) and over 2.6 when utilizing the entire system using hybrid CPU+GPU solution with 2 GPUs and 5 cores (instead of 7 cores per node). Finally, we analyze the implementation behavior on future GPU systems.« less

48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2010 CFR

2010-10-01

... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to service-disabled...

48 CFR 19.1406 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2011 CFR

2011-10-01

... service-disabled veteran-owned small business concerns. 19.1406 Section 19.1406 Federal Acquisition...-Disabled Veteran-Owned Small Business Procurement Program 19.1406 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to service-disabled...

48 CFR 227.7204 - Contracts under the Small Business Innovative Research Program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Business Innovative Research Program. 227.7204 Section 227.7204 Federal Acquisition Regulations System... under the Small Business Innovative Research Program. When contracting under the Small Business Innovative Research Program, follow the procedures at 227-7104. ...

13 CFR 127.101 - What type of assistance is available under this part?

Code of Federal Regulations, 2011 CFR

2011-01-01

... ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT ASSISTANCE PROCEDURES (Eff. until 2-4-11) General... analysis (including analysis of its own procurement history), that the set-aside would meet all applicable...

48 CFR 19.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2013 CFR

2013-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a... data from the 8(a) contractor. If the SBA requests audit assistance to determine the proposed price to... requested by the SBA, the contracting officer shall make available the data used to estimate the fair market...

48 CFR 19.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2012 CFR

2012-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a... data from the 8(a) contractor. If the SBA requests audit assistance to determine the proposed price to... requested by the SBA, the contracting officer shall make available the data used to estimate the fair market...

48 CFR 19.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2011 CFR

2011-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a... data from the 8(a) contractor. If the SBA requests audit assistance to determine the proposed price to... requested by the SBA, the contracting officer shall make available the data used to estimate the fair market...

48 CFR 19.806 - Pricing the 8(a) contract.

Code of Federal Regulations, 2014 CFR

2014-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a... data from the 8(a) contractor. If the SBA requests audit assistance to determine the proposed price to... requested by the SBA, the contracting officer shall make available the data used to estimate the fair market...

Selection against small males in utero: a test of the Wells hypothesis

PubMed Central

Catalano, R.; Goodman, J.; Margerison-Zilko, C.E.; Saxton, K.B.; Anderson, E.; Epstein, M.

2012-01-01

BACKGROUND The argument that women in stressful environments spontaneously abort their least fit fetuses enjoys wide dissemination despite the fact that several of its most intuitive predictions remain untested. The literature includes no tests, for example, of the hypothesis that these mechanisms select against small for gestational age (SGA) males. METHODS We apply time-series modeling to 4.9 million California male term births to test the hypothesis that the rate of SGA infants in 1096 weekly birth cohorts varies inversely with labor market contraction, a known stressor of contemporary populations. RESULTS We find support for the hypothesis that small size becomes less frequent among term male infants when the labor market contracts. CONCLUSIONS Our findings contribute to the evidence supporting selection in utero. They also suggest that research into the association between maternal stress and adverse birth outcomes should acknowledge the possibility that fetal loss may affect findings and their interpretation. Strengths of our analyses include the large number and size of our birth cohorts and our control for autocorrelation. Weaknesses include that we, like nearly all researchers in the field, have no direct measure of fetal loss. PMID:22298840

Department of Defense Small Business (SB) Program: A Knowledge-Level Analysis of How Customer Education Relates to Meeting SB Goals

DTIC Science & Technology

2014-12-01

xiii SB small business SBA Small Business Administration SBP small business program SBS small business specialist SDB small disadvantaged business...government contracts. 2. Small Disadvantaged Business The purpose of the Small Disadvantaged Business ( SDB ) program is to increase opportunities for...socially and economically disadvantaged businesses to compete for contract awards. A SDB is “a small business that is at least 51 percent owned by one

48 CFR 1419.201 - General policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SMALL BUSINESS PROGRAMS Policies 1419.201 General policy. HCAs, without the power of redelegation, shall... participation of small business and small disadvantaged businesses in contract and subcontract opportunities. Goals for contract awards to minority business enterprises and women-owned businesses shall also be...

48 CFR 1419.201 - General policy.

Code of Federal Regulations, 2011 CFR

2011-10-01

... SMALL BUSINESS PROGRAMS Policies 1419.201 General policy. HCAs, without the power of redelegation, shall... participation of small business and small disadvantaged businesses in contract and subcontract opportunities. Goals for contract awards to minority business enterprises and women-owned businesses shall also be...

Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels.

PubMed

Kobayashi, Tetsu; Kim, HuiJung; Liu, Xiangde; Sugiura, Hisatoshi; Kohyama, Tadashi; Fang, Qiuhong; Wen, Fu-Qiang; Abe, Shinji; Wang, Xingqi; Atkinson, Jeffrey J; Shipley, James M; Senior, Robert M; Rennard, Stephen I

2014-06-01

Matrix metalloproteinase-9 (MMP-9) is a matrix-degrading enzyme implicated in many biological processes, including inflammation. It is produced by many cells, including fibroblasts. When cultured in three-dimensional (3D) collagen gels, fibroblasts contract the surrounding matrix, a function that is thought to model the contraction that characterizes both normal wound repair and fibrosis. The current study was designed to evaluate the role of endogenously produced MMP-9 in fibroblast contraction of 3D collagen gels. Fibroblasts from mice lacking expression of MMP-9 and human lung fibroblasts (HFL-1) transfected with MMP-9 small-interfering RNA (siRNA) were used. Fibroblasts were cast into type I collagen gels and floated in culture medium with or without transforming growth factor (TGF)-β1 for 5 days. Gel size was determined daily using an image analysis system. Gels made from MMP-9 siRNA-treated human fibroblasts contracted less than control fibroblasts, as did fibroblasts incubated with a nonspecific MMP inhibitor. Similarly, fibroblasts cultured from MMP-9-deficient mice contracted gels less than did fibroblasts from control mice. Transfection of the MMP-9-deficient murine fibroblasts with a vector expressing murine MMP-9 restored contractile activity to MMP-9-deficient fibroblasts. Inhibition of MMP-9 reduced active TGF-β1 and reduced several TGF-β1-driven responses, including activity of a Smad3 reporter gene and production of fibronectin. Because TGF-β1 also drives fibroblast gel contraction, this suggests the mechanism for MMP-9 regulation of contraction is through the generation of active TGF-β1. This study provides direct evidence that endogenously produced MMP-9 has a role in regulation of tissue contraction of 3D collagen gels mediated by fibroblasts. Copyright © 2014 the American Physiological Society.

48 CFR 1832.501-1 - Customary progress payment rates. (NASA supplements paragraph (a))

Code of Federal Regulations, 2010 CFR

2010-10-01

... (a)) (a) The customary progress payment rate for all NASA contracts is 85 percent for large business, 90 percent for small business, 95 percent for small disadvantaged business, and 100 percent for Phase II contracts in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer...

48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2010 CFR

2010-10-01

... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2011 CFR

2011-10-01

... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2014 CFR

2014-10-01

... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2012 CFR

2012-10-01

... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

48 CFR 819.7007 - Sole source awards to service-disabled veteran-owned small business concerns.

Code of Federal Regulations, 2013 CFR

2013-10-01

... service-disabled veteran-owned small business concerns. 819.7007 Section 819.7007 Federal Acquisition...-Disabled Veteran-Owned and Veteran-Owned Small Business Acquisition Program 819.7007 Sole source awards to service-disabled veteran-owned small business concerns. (a) A contracting officer may award contracts to...

Rothe Development Corporation v. Department of Defense: The Constitutionality of Federal Contracting Programs for Minority-Owned and Other Small Business

DTIC Science & Technology

2009-03-16

not have sufficient evidence to conclude that there was racial discrimination in defense contracting when it reauthorized the program in 2006. This...report examines the Rothe decision in detail; describes existing contracting programs for minority-owned and women -owned small businesses; and analyzes

77 FR 47797 - Federal Acquisition Regulation; Small Business Set Asides for Research and Development Contracts

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-10

... Acquisition Regulation; Small Business Set Asides for Research and Development Contracts AGENCY: Department of... Acquisition Regulation (FAR) to clarify that contracting officers shall set aside acquisitions for research..., and NASA are proposing to amend the Federal Acquisition Regulation (FAR) to revise paragraph (b)(2) of...

13 CFR 127.500 - In what industries is a contracting officer authorized to restrict competition under this part?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false In what industries is a contracting officer authorized to restrict competition under this part? 127.500 Section 127.500 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT...

48 CFR 1827.303 - Contract clauses. (NASA supplements paragraphs (a), (b), (c) and (d))

Code of Federal Regulations, 2011 CFR

2011-10-01

..., a prospective contractor may be required to represent itself as either a small business firm or a... contracting officer may file a protest in accordance with FAR 19.302 if small business firm status is... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND...

48 CFR 1827.303 - Contract clauses. (NASA supplements paragraphs (a), (b), (c) and (d))

Code of Federal Regulations, 2010 CFR

2010-10-01

..., a prospective contractor may be required to represent itself as either a small business firm or a... contracting officer may file a protest in accordance with FAR 19.302 if small business firm status is... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND...

Biology Notes.

ERIC Educational Resources Information Center

School Science Review, 1980

1980-01-01

Outlines a variety of laboratory procedures, discussions, and demonstrations including in vitro contraction of muscle fibres and muscle proteins, sucrose density-gradient centrifugation, fern spore development, digestion of starch, construction of a small mammal trap, microscope selection, and occurrence and toxicity of mycotoxins. (GS)

13 CFR 125.14 - What are SDVO contracts?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What are SDVO contracts? 125.14 Section 125.14 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS Contracting with SDVO SBCs § 125.14 What are SDVO contracts? SDVO contracts are contracts awarded...

Small Business Innovations (Robotic Wrist)

NASA Technical Reports Server (NTRS)

1991-01-01

Under a Langley Research Center Small Business Innovation Research (SBIR) contract, Ross-Hime Designs, Inc. Minneapolis, MN, developed the Omni-Wrist actuator, which has a 25-pound capacity, 180 degrees of pitch/yaw, and 360 degrees of roll. Company literature calls it "the first successful singularity-free high-precision (robotic) wrist." Applications include spray painting, sealing, ultrasonic testing, welding and a variety of nuclear industry, aerospace and military uses.

Rothe Development Corporation v. Department of Defense: The Constitutionality of Federal Contracting Programs for Minority-Owned and Other Small Businesses

DTIC Science & Technology

2009-04-14

and analyzes Rothe’s potential effect on these programs, including the Business Development Program under Section 8(a) of the Small Business Act...13 Potential Vulnerability of Existing Programs... Newell , Decision in Defense Procurement Case Could Set Precedent, GovExec.com, Nov. 11, 2008, available at http://www.govexec.com/dailyfed/1108

48 CFR 9.105-2 - Determinations and documentation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... a responsive small business lacks certain elements of responsibility, the contracting officer shall... business concern (see subpart 19.6), the contracting officer shall accept the Small Business Administration... integrity and business ethics; and (C) The Small Business Administration does not issue a Certificate of...

48 CFR 9.105-2 - Determinations and documentation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... a responsive small business lacks certain elements of responsibility, the contracting officer shall... business concern (see subpart 19.6), the contracting officer shall accept the Small Business Administration... integrity and business ethics; and (C) The Small Business Administration does not issue a Certificate of...

48 CFR 9.105-2 - Determinations and documentation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... a responsive small business lacks certain elements of responsibility, the contracting officer shall... business concern (see subpart 19.6), the contracting officer shall accept the Small Business Administration... integrity and business ethics; and (C) The Small Business Administration does not issue a Certificate of...

76 FR 16703 - Small Business Jobs Act Tour: Selected Provisions Having an Effect on Government Contracting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-25

... or cooperative research and development set aside for small business concerns shall be deemed an... SMALL BUSINESS ADMINISTRATION 13 CFR Parts 121, 124, 125, 126, and 127 [Docket No. SBA-2011-0006] Small Business Jobs Act Tour: Selected Provisions Having an Effect on Government Contracting AGENCY: U.S...

36 CFR 223.103 - Award of small business set-aside sales.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Award of small business set... PRODUCTS Timber Sale Contracts Award of Contracts § 223.103 Award of small business set-aside sales. If timber is advertised as set aside for competitive bidding by small business concerns, award will be made...

36 CFR 223.103 - Award of small business set-aside sales.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Award of small business set... PRODUCTS Timber Sale Contracts Award of Contracts § 223.103 Award of small business set-aside sales. If timber is advertised as set aside for competitive bidding by small business concerns, award will be made...

36 CFR 223.103 - Award of small business set-aside sales.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Award of small business set... PRODUCTS Timber Sale Contracts Award of Contracts § 223.103 Award of small business set-aside sales. If timber is advertised as set aside for competitive bidding by small business concerns, award will be made...

36 CFR 223.103 - Award of small business set-aside sales.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Award of small business set... PRODUCTS Timber Sale Contracts Award of Contracts § 223.103 Award of small business set-aside sales. If timber is advertised as set aside for competitive bidding by small business concerns, award will be made...

Policy Development for Research Grants, and Contracts Administration in the Small College or University.

ERIC Educational Resources Information Center

Lyons, Paul R.

Some of the major administrative factors that will require attention by small colleges and universities as they develop policy and general procedures for the administration of research, grants, and contracts are considered. Management of research, grants, and contracts is a process that involves the review and approval of proposals; project…

48 CFR 4.1201 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... in paragraph (b) of the clause at 52.219-28, Post-Award Small Business Program Rerepresentation, apply, contractors that represented they were small businesses prior to award of a contract must update... they were other than small businesses prior to award of a contract may update the representations and...

48 CFR 4.1201 - Policy.

Code of Federal Regulations, 2011 CFR

2011-10-01

... in paragraph (b) of the clause at 52.219-28, Post-Award Small Business Program Rerepresentation, apply, contractors that represented they were small businesses prior to award of a contract must update... they were other than small businesses prior to award of a contract may update the representations and...

48 CFR 227.7204 - Contracts under the Small Business Innovation Research Program.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Business Innovation Research Program. 227.7204 Section 227.7204 Federal Acquisition Regulations System... under the Small Business Innovation Research Program. When contracting under the Small Business Innovation Research Program, follow the procedures at 227-7104. [56 FR 36389, July 31, 1991, as amended at 76...

48 CFR 227.7204 - Contracts under the Small Business Innovation Research Program.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Business Innovation Research Program. 227.7204 Section 227.7204 Federal Acquisition Regulations System... under the Small Business Innovation Research Program. When contracting under the Small Business Innovation Research Program, follow the procedures at 227-7104. [56 FR 36389, July 31, 1991, as amended at 76...

48 CFR 227.7204 - Contracts under the Small Business Innovation Research Program.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Business Innovation Research Program. 227.7204 Section 227.7204 Federal Acquisition Regulations System... under the Small Business Innovation Research Program. When contracting under the Small Business Innovation Research Program, follow the procedures at 227-7104. [56 FR 36389, July 31, 1991, as amended at 76...

48 CFR 227.7204 - Contracts under the Small Business Innovation Research Program.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Business Innovation Research Program. 227.7204 Section 227.7204 Federal Acquisition Regulations System... under the Small Business Innovation Research Program. When contracting under the Small Business Innovation Research Program, follow the procedures at 227-7104. [56 FR 36389, July 31, 1991, as amended at 76...

Contraction design for small low-speed wind tunnels

NASA Technical Reports Server (NTRS)

Bell, James H.; Mehta, Rabindra D.

1988-01-01

An iterative design procedure was developed for two- or three-dimensional contractions installed on small, low-speed wind tunnels. The procedure consists of first computing the potential flow field and hence the pressure distributions along the walls of a contraction of given size and shape using a three-dimensional numerical panel method. The pressure or velocity distributions are then fed into two-dimensional boundary layer codes to predict the behavior of the boundary layers along the walls. For small, low-speed contractions it is shown that the assumption of a laminar boundary layer originating from stagnation conditions at the contraction entry and remaining laminar throughout passage through the successful designs if justified. This hypothesis was confirmed by comparing the predicted boundary layer data at the contraction exit with measured data in existing wind tunnels. The measured boundary layer momentum thicknesses at the exit of four existing contractions, two of which were 3-D, were found to lie within 10 percent of the predicted values, with the predicted values generally lower. From the contraction wall shapes investigated, the one based on a fifth-order polynomial was selected for installation on a newly designed mixing layer wind tunnel.

Contraction design for small low-speed wind tunnels

NASA Technical Reports Server (NTRS)

Bell, James H.; Mehta, Rabindra D.

1988-01-01

An iterative design procedure was developed for 2- or 3-dimensional contractions installed on small, low speed wind tunnels. The procedure consists of first computing the potential flow field and hence the pressure distributions along the walls of a contraction of given size and shape using a 3-dimensional numerical panel method. The pressure or velocity distributions are then fed into 2-dimensional boundary layer codes to predict the behavior of the boundary layers along the walls. For small, low speed contractions, it is shown that the assumption of a laminar boundary layer originating from stagnation conditions at the contraction entry and remaining laminar throughout passage through the successful designs is justified. This hypothesis was confirmed by comparing the predicted boundary layer data at the contraction exit with measured data in existing wind tunnels. The measured boundary layer momentum thicknesses at the exit of four existing contractions, two of which were 3-D, were found to lie within 10 percent of the predicted values, with the predicted values generally lower. From the contraction wall shapes investigated, the one based on a 5th order polynomial was selected for newly designed mixing wind tunnel installation.

48 CFR 1819.7205 - Mentor-protégé agreements.

Code of Federal Regulations, 2014 CFR

2014-10-01

...://www.osbp.nasa.gov. ... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7205 Mentor... agreement as a condition for award of a contract by the mentor, including a subcontract under a NASA...

48 CFR 1819.7205 - Mentor-protégé agreements.

Code of Federal Regulations, 2012 CFR

2012-10-01

...://www.osbp.nasa.gov. ... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7205 Mentor... agreement as a condition for award of a contract by the mentor, including a subcontract under a NASA...

48 CFR 1819.7205 - Mentor-protégé agreements.

Code of Federal Regulations, 2011 CFR

2011-10-01

...://www.osbp.nasa.gov. ... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7205 Mentor... agreement as a condition for award of a contract by the mentor, including a subcontract under a NASA...

48 CFR 1819.7205 - Mentor-protégé agreements.

Code of Federal Regulations, 2013 CFR

2013-10-01

...://www.osbp.nasa.gov. ... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7205 Mentor... agreement as a condition for award of a contract by the mentor, including a subcontract under a NASA...

Psychological contracts and commitment amongst nurses and nurse managers: a discourse analysis.

PubMed

McCabe, T J; Sambrook, Sally

2013-07-01

Few studies explore the link between the psychological contracts and the commitment of nursing professionals in the healthcare sector, and how perceived breaches of the psychological contract can impact on nurses' commitment levels. This study explores the connections between the psychological contracts and organisational and professional commitment of nurses and nurse managers. Semi-structured interviews were conducted with nurses and nurse managers, to explore the connections between their psychological contracts and organisational and professional commitment. Large acute and small community organisation within the British National Health Service. 28 nurses and 11 nurse managers working within an acute and a community sector organisation - 20 and 19 in each organisation. Participants were selected through a process of purposive sampling, reflecting variations in terms of age, grade, ward and tenure. A discourse analysis was conducted on the qualitative data from the thirty nine semi-structured interviews. Two overall themes emerged, professional and managerial values. Professional values included the sub-themes: professional recognition; immediate work environment - leadership and peer support; professional development and progression. Sub-themes under managerial values included: involvement; general management; resource management. The findings suggest that nurses and nurse managers are governed by relational psychological contracts, underpinned by an affective and to a lesser extent normative commitment towards the nursing profession. They emphasise 'professional values', and professional commitment, as the basis for positive psychological contracts amongst nursing professionals. There was anecdotal evidence of relational psychological contract breach, with decreasing job satisfaction as the outcome of perceived psychological contract breach. Positive psychological contracts and commitment levels amongst nursing professionals can be supported by managers been aware and sensitive to nursing discourses, and managing their expectations through greater involvement and leadership development. Copyright © 2012 Elsevier Ltd. All rights reserved.

Small Scale Polygons and the History of Ground Ice on Mars

NASA Technical Reports Server (NTRS)

Mellon, Michael T.

2003-01-01

Recent progress on polygon modeling has focused on the diameter and surface relief that we expect of thermal-contraction polygons in martian permafrost. With this in mind, we developed a finite-element model of thermal-contraction-crack behavior in permafrost in a martian climate. This model was generated from a finite element code by Jay Melosh (called TECTON) originally developed for terrestrial and planetary crustal-deformation studies. We adapted this model to martian permafrost by including time (and temperature) dependent rheologies, boundary conditions, and isotropic thermal-contraction, as well as several small adaptations to a martian environment. We tested our model extensively, including comparison to an analytic solution of pre-fracture stress. We recently published an analysis of two potential sources of water for forming the recent gullies. In this work we first evaluated the potential for near-surface ground ice (in the top meter or so of soil) to melt under conditions of solar heating on sloped surfaces at high obliquity, utilizing both thermal and diffusion-based ground-ice-stability models; our results suggested that the ground ice will sublimate, and the ice table will recede to greater depths before the melting temperature can be reached. An exception can occur only for extremely salt-rich ice, depressing the freezing point.

13 CFR 127.603 - What are the requirements for filing an EDWOSB or WOSB protest?

Code of Federal Regulations, 2010 CFR

2010-01-01

... ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT ASSISTANCE PROCEDURES Protests § 127.603 What are the... (202) 205-6390, Attn: Women-Owned Small Business Status Protest. The contracting officer's referral...

7 CFR 226.22 - Procurement standards.

Code of Federal Regulations, 2010 CFR

2010-01-01

... pertinent to the following: rationale for the method of procurement, selection of contract type, contractor... competition. The description may include a statement of the qualitative nature of the material, product or... technical resources. (i) Program procurements shall be made by one of the following methods: (1) Small...

48 CFR 36.213-2 - Presolicitation notices.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the location of the work; (3) Include tentative dates for issuing invitations, opening bids, and completing contract performance; (4) State where plans will be available for inspection without charge; (5... is restricted to small businesses; and (7) Specify any amount to be charged for solicitation...

Lightweight Material Patches Allow for Quick Repairs

NASA Technical Reports Server (NTRS)

2010-01-01

Cornerstone Research Group Inc., of Dayton, Ohio, has been the recipient of 16 Small Business Innovation Research (SBIR) contracts with NASA with a variety of different focuses, including projects like creating inflatable structures for radio frequency antennas and, most recently, healable polymer matrix composites for future space vehicles. One of its earlier SBIR contracts, with Kennedy Space Center, led to the development of a new type of structural patch for a variety of consumer uses: Rubbn Repair, for automotive uses; and Rec Repair for the outdoors and adventure market. Both are flexible, heat-activated structural patches.

48 CFR 1827.304-3 - Contracts for construction work or architect-engineer services. (NASA supplements paragraph (a))

Code of Federal Regulations, 2014 CFR

2014-10-01

... architect-engineer services contracts with other than a small business or nonprofit organization, see 1827... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 1827.304-3 Contracts for...

48 CFR 1827.304-3 - Contracts for construction work or architect-engineer services. (NASA supplements paragraph (a))

Code of Federal Regulations, 2013 CFR

2013-10-01

... architect-engineer services contracts with other than a small business or nonprofit organization, see 1827... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 1827.304-3 Contracts for...

48 CFR 1827.304-3 - Contracts for construction work or architect-engineer services. (NASA supplements paragraph (a))

Code of Federal Regulations, 2011 CFR

2011-10-01

... architect-engineer services contracts with other than a small business or nonprofit organization, see 1827... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 1827.304-3 Contracts for...

48 CFR 1827.304-3 - Contracts for construction work or architect-engineer services. (NASA supplements paragraph (a))

Code of Federal Regulations, 2012 CFR

2012-10-01

... architect-engineer services contracts with other than a small business or nonprofit organization, see 1827... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 1827.304-3 Contracts for...

Volume shift and charge instability of simple-metal clusters

NASA Astrophysics Data System (ADS)

Brajczewska, M.; Vieira, A.; Fiolhais, C.; Perdew, J. P.

1996-12-01

Experiment indicates that small clusters show changes (mostly contractions) of the bond lengths with respect to bulk values. We use the stabilized jellium model to study the self-expansion and self-compression of spherical clusters (neutral or ionized) of simple metals. Results from Kohn - Sham density functional theory are presented for small clusters of Al and Na, including negatively-charged ones. We also examine the stability of clusters with respect to charging.

Tapping Transaction Costs to Forecast Acquisition Cost Breaches

DTIC Science & Technology

2016-01-01

Diameter Bomb Increment II (SDB II) Space Based Infrared System (SBIRS) High Program Standard Missile (SM) - 2 Block IV Stryker Family of Vehicles...some limitations. First, the activities included in this category will vary somewhat from contractor to contractor. As a result, a small portion of...contract may vary over time as new costs are defined by the contractor as being related to SE/PM. This could explain a small portion of the increase in

Defense Acquisition Research Journal. Volume 20, Number 3, Issue 67, October 2013

DTIC Science & Technology

2013-10-01

Contracting Operations (PZCO) FIGURE 4. CONTRACTING PHASE ZERO: PLAN, EXERCISE, REHEARSE, AND SYNCHRONIZE Note. BPA = Blanket Purchase Agreement; COCO...Construction Supplies; Oce Equipment; Quality of Life; and Morale, Welfare, and Recreation PO/TO/DO/ BPA Small Purchase Standard Vehicles PO/TO/DO/ BPA Small...Purchase Standard Vehicles PO/TO/DO/ BPA Small Purchase Standard Vehicles PO/TO/DO/ BPA Small Purchase Food, Water, Billeting, Hygiene; Transportation

The Effect of Acquisition Reform on Small Business Participation in the Federal Marketplace

DTIC Science & Technology

2004-03-01

and whose management and daily business operations are controlled by one or more such individuals. 6 3. Set-Aside for Small Business The...to address Contract Bundling: a. Ensure Accountability of Senior Agency Management for Improving Contracting Opportunities for Small Business ...and whose management and daily business operations are controlled by one or more women [Ref. 20:p. 20]. 7. Veteran Owned Small Business (VOSB) and

48 CFR 252.219-7003 - Small business subcontracting plan (DoD contracts).

Code of Federal Regulations, 2011 CFR

2011-10-01

... clause— Historically black colleges and universities means institutions determined by the Secretary of... institution that was an integral part of such a college or university before November 14, 1986. Minority... clause, includes historically black colleges and universities and minority institutions, in addition to...

48 CFR 252.219-7003 - Small business subcontracting plan (DoD contracts).

Code of Federal Regulations, 2014 CFR

2014-10-01

... clause— Historically black colleges and universities means institutions determined by the Secretary of... institution that was an integral part of such a college or university before November 14, 1986. Minority... clause, includes historically black colleges and universities and minority institutions, in addition to...

48 CFR 252.219-7003 - Small business subcontracting plan (DoD contracts).

Code of Federal Regulations, 2013 CFR

2013-10-01

... clause— Historically black colleges and universities means institutions determined by the Secretary of... institution that was an integral part of such a college or university before November 14, 1986. Minority... clause, includes historically black colleges and universities and minority institutions, in addition to...

48 CFR 252.219-7003 - Small business subcontracting plan (DoD contracts).

Code of Federal Regulations, 2012 CFR

2012-10-01

... clause— Historically black colleges and universities means institutions determined by the Secretary of... institution that was an integral part of such a college or university before November 14, 1986. Minority... clause, includes historically black colleges and universities and minority institutions, in addition to...

Bridge-in-a-Backpack(TM). Task 8 : investigation of bridge performance under extreme temperatures.

DOT National Transportation Integrated Search

2014-12-01

This report includes fulfillment of Task 8 of a multi-task contract to further enhance concrete filled FRP tubes, or : the Bridge in a Backpack. : One recurring question has been its performance in fire conditions, mainly small campfires and handheld...

Risk factors for injury among construction workers at Denver International Airport.

PubMed

Lowery, J T; Borgerding, J A; Zhen, B; Glazner, J E; Bondy, J; Kreiss, K

1998-08-01

The Denver International Airport construction project provided a rare opportunity to identify risk factors for injury on a large construction project for which 769 contractors were hired to complete 2,843 construction contracts. Workers' compensation claims and payroll data for individual contracts were recorded in an administrative database developed by the project's Owner-Controlled Insurance Program. From claims andy payroll data linked with employee demographic information, we calculated injury rates per 200,000 person-hours by contract and over contract characteristics of interest. We used Poisson regression models to examine contract-specific risk factors in relation to total injuries, lost-work-time (LWT), and non-LWT injuries. We included contract-specific expected loss rates (ELRs) in the model to control for prevailing risk of work and used logistic regression methods to determine the association between LWT and non-LWT injuries on contracts. Injury rates were highest during the first year of construction, at the beginning of contracts, and among older workers. Risk for total and non-LWT injuries was elevated for building construction contracts, contract for special trades companies (SIC 17), contracts with payrolls over $1 million, and those with overtime payrolls greater than 20%. Risk for LWT injuries only was increased for site development contracts and contract starting in the first year of construction. Contracts experiencing one or more minor injuries were four times as likely to have at least one major injury (OR = 4.0, 95% CI (2.9, 5.5)). Enhancement of DIA's safety infrastructure during the second year of construction appears to have been effective in reducing serious (LWT) injures. The absence of correlation between injury rates among contracts belonging to the same company suggest that targeting of safety resources at the level of the contract may be an effective approach to injury prevention. Interventions focused on high-risk contracts, including those with considerable overtime work, contracts held by special trades contractors (SIC 17), and contracts belonging to small and mid-sized companies, and on high-risk workers, such as those new to a construction site or new to a contract may reduce injury burden on large construction sites. The join occurrence of minor and major injuries on a contract level suggests that surveillance of minor injuries may be useful in identifying opportunities for prevention of major injures.

48 CFR 3019.708 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Contract clauses. 3019.708 Section 3019.708 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY ACQUISITION REGULATION (HSAR) SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting...

Small Business Innovation Research GRC Phase I, Phase II, and Post-Phase II Opportunity Assessment for 2015

NASA Technical Reports Server (NTRS)

Nguyen, Hung D.; Steele, Gynelle C.

2016-01-01

This report outlines the 2015 Small Business Innovation Research/Small Business Technology Transfer (SBIR/STTR) Phase I, Phase II, and Post-Phase II opportunity contract award results associated with NASA's Aeronautics Research Mission Directorate (ARMD), Human Exploration and Operations Mission Directorate (HEOMD), Science Mission Directorate (SMD), and Space Technology Mission Directorate (STMD) for NASA Glenn Research Center. The report also highlights the number of Phase I, Phase II, and Post-Phase II contracts awarded by mission directorate. The 2015 Phase I contract awards to companies in Ohio and their corresponding technologies are also discussed.

The Pilot Mentor-Protege Program: A Viable Program for Government Procurement

DTIC Science & Technology

1993-06-01

Protege, Small Disadvantaged Business, Government Contracting 19 Abstract (continue on reverse if necessaryj and identif by block number) The Pilot Mentor...developmental assistance to Small Disadvantaged Businesses (SDBs). The developmental assistance provided should enhance the capabilities of SD)Bs to perform...as subcontractfors and suppliers under Government and commercial contracts and increase Small Disadvantaged Business participation in Department of

NASA SBIR abstracts of 1991 phase 1 projects

NASA Technical Reports Server (NTRS)

Schwenk, F. Carl; Gilman, J. A.; Paige, J. B.

1992-01-01

The objectives of 301 projects placed under contract by the Small Business Innovation Research (SBIR) program of the National Aeronautics and Space Administration (NASA) are described. These projects were selected competitively from among proposals submitted to NASA in response to the 1991 SBIR Program Solicitation. The basic document consists of edited, non-proprietary abstracts of the winning proposals submitted by small businesses. The abstracts are presented under the 15 technical topics within which Phase 1 proposals were solicited. Each project was assigned a sequential identifying number from 001 to 301, in order of its appearance in the body of the report. Appendixes to provide additional information about the SBIR program and permit cross-reference of the 1991 Phase 1 projects by company name, location by state, principal investigator, NASA Field Center responsible for management of each project, and NASA contract number are included.

NASA SBIR abstracts of 1992, phase 1 projects

NASA Technical Reports Server (NTRS)

Schwenk, F. C.; Gilman, J. A.; Paige, J. B.; Sacknoff, S. M.

1993-01-01

The objectives of 346 projects placed under contract by the Small Business Innovation Research (SBIR) program of the National Aeronautics and Space Administration (NASA) are described. These projects were selected competitively from among proposals submitted to NASA in response to the 1992 SBIR Program Solicitation. The basic document consists of edited, non-proprietary abstracts of the winning proposals submitted by small businesses. The abstracts are presented under the 15 technical topics within which Phase 1 proposals were solicited. Each project was assigned a sequential identifying number from 001 to 346, in order of its appearance in the body of the report. Appendixes to provide additional information about the SBIR program and permit cross-reference of the 1992 Phase 1 projects by company name, location by state, principal investigator, NASA Field Center responsible for management of each project, and NASA contract number are included.

NASA SBIR abstracts of 1990 phase 1 projects

NASA Technical Reports Server (NTRS)

Schwenk, F. C.; Gilman, J. A.; Paige, J. B.

1991-01-01

The research objectives of the 280 projects placed under contract in the National Aeronautics and Space Administration (NASA) 1990 Small Business Innovation Research (SBIR) Phase 1 program are described. The basic document consists of edited, non-proprietary abstracts of the winning proposals submitted by small businesses in response to NASA's 1990 SBIR Phase 1 Program Solicitation. The abstracts are presented under the 15 technical topics within which Phase 1 proposals were solicited. Each project was assigned a sequential identifying number from 001 to 280, in order of its appearance in the body of the report. The document also includes Appendixes to provide additional information about the SBIR program and permit cross-reference in the 1990 Phase 1 projects by company name, location by state, principal investigator, NASA field center responsible for management of each project, and NASA contract number.

NAVSUP Global Logistics Support

DTIC Science & Technology

2012-08-01

Support $3.5 M Ill SB Contracting Actions Ill SB Value 35% of total spend to Small Business ! NAVAL SUPPLY SYSTEMS COMMAND • Procurement • Barge...Other services now using as well • Awarded Aug 2011, Features: • 100% Sma II Business Set Aside ! • 25 multiple award task order contracts to 8...UP- GLOBAL LOGISTICS I · -~ --; •• ~.c. SUPPORT ,.. NAVAL SUPPLY SYSTEMS COMMAND Fiscal Year 2011 Small Business Contracting Spend: 28,000 actions

49 CFR Appendix A to Part 19 - Contract Provisions

Code of Federal Regulations, 2010 CFR

2010-10-01

... market, or contracts for transportation or transmission of intelligence. 5. Rights to Inventions Made... Organizations and Small Business Firms Under Government Grants, Contracts and Cooperative Agreements,” and any...

41 CFR Appendix A to Part 105 - 72-Contract Provisions

Code of Federal Regulations, 2010 CFR

2010-07-01

... market, or contracts for transportation or transmission of intelligence. 5. Rights to Inventions Made... Organizations and Small Business Firms Under Government Grants, Contracts and Cooperative Agreements,” and any...

48 CFR 819.7004 - Contracting Order of Priority.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contracting Order of Priority. 819.7004 Section 819.7004 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Service-Disabled Veteran-Owned and Veteran-Owned Small Business...

48 CFR 819.7004 - Contracting Order of Priority.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Contracting Order of Priority. 819.7004 Section 819.7004 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Service-Disabled Veteran-Owned and Veteran-Owned Small Business...

48 CFR 12.303 - Contract format.

Code of Federal Regulations, 2010 CFR

2010-10-01

... a price evaluation adjustment for small disadvantaged business concerns is applicable (the... for emerging small businesses; (2) Block 18B for remittance address; (3) Block 19 for contract line item numbers; (4) Block 20 for schedule of supplies/services; or (5) Block 25 for accounting data; (c...

48 CFR 47.303-17 - Contractor-prepaid commercial bills of lading, small package shipments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TRANSPORTATION Transportation in Supply... advantageous to the Government, the contracting officer may authorize the contractor to ship supplies, which... subsection, do not require a contract modification. Unless otherwise provided in the contract, the supplies...

Geometric estimation of intestinal contraction for motion tracking of video capsule endoscope

NASA Astrophysics Data System (ADS)

Mi, Liang; Bao, Guanqun; Pahlavan, Kaveh

2014-03-01

Wireless video capsule endoscope (VCE) provides a noninvasive method to examine the entire gastrointestinal (GI) tract, especially small intestine, where other endoscopic instruments can barely reach. VCE is able to continuously provide clear pictures in short fixed intervals, and as such researchers have attempted to use image processing methods to track the video capsule in order to locate the abnormalities inside the GI tract. To correctly estimate the speed of the motion of the endoscope capsule, the radius of the intestinal track must be known a priori. Physiological factors such as intestinal contraction, however, dynamically change the radius of the small intestine, which could bring large errors in speed estimation. In this paper, we are aiming to estimate the radius of the contracted intestinal track. First a geometric model is presented for estimating the radius of small intestine based on the black hole on endoscopic images. To validate our proposed model, a 3-dimentional virtual testbed that emulates the intestinal contraction is then introduced in details. After measuring the size of the black holes on the test images, we used our model to esimate the radius of the contracted intestinal track. Comparision between analytical results and the emulation model parameters has verified that our proposed method could preciously estimate the radius of the contracted small intestine based on endoscopic images.

48 CFR 1815.208 - Submission, modification, revision, and withdrawal of proposals. (NASA supplements paragraph (b))

Code of Federal Regulations, 2010 CFR

2010-10-01

... late proposal criteria do not apply to Announcements of Opportunity, NASA Research Announcements, and Small Business Innovative Research (SBIR) Phase I and Phase II solicitations, and Small Business... Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CONTRACTING METHODS AND CONTRACT...

48 CFR 719.271-4 - Heads of contracting activities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... activities. 719.271-4 Section 719.271-4 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 719.271-4 Heads of contracting activities. In order for the agency small business program to be effective, the active support of top management...

48 CFR 19.202-4 - Solicitation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... citations to each major Federal law or agency rule with which such business concern must comply in performing such contract other than laws or agency rules with which the small business must comply when doing... PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-4 Solicitation. The contracting officer must encourage...

48 CFR 42.502 - Selecting contracts for postaward orientation.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., and complexity of the contract; (c) Complexity and acquisition history of the product or service; (d... subcontracting; (h) Contractor's performance history and experience with the product or service; (i) Contractor's status, if any, as a small business, small disadvantaged, women-owned, veteran-owned, HUBZone, or service...

48 CFR 42.502 - Selecting contracts for postaward orientation.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., and complexity of the contract; (c) Complexity and acquisition history of the product or service; (d... subcontracting; (h) Contractor's performance history and experience with the product or service; (i) Contractor's status, if any, as a small business, small disadvantaged, women-owned, veteran-owned, HUBZone, or service...

48 CFR 42.502 - Selecting contracts for postaward orientation.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., and complexity of the contract; (c) Complexity and acquisition history of the product or service; (d... subcontracting; (h) Contractor's performance history and experience with the product or service; (i) Contractor's status, if any, as a small business, small disadvantaged, women-owned, veteran-owned, HUBZone, or service...

48 CFR 42.502 - Selecting contracts for postaward orientation.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., and complexity of the contract; (c) Complexity and acquisition history of the product or service; (d... subcontracting; (h) Contractor's performance history and experience with the product or service; (i) Contractor's status, if any, as a small business, small disadvantaged, women-owned, veteran-owned, HUBZone, or service...

TANK OPERATIONS CONTRACT CONSTRUCTION MANAGEMENT METHODOLOGY UTILIZING THE AGENCY METHOD OF CONSTRUCTION MANAGEMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

LESKO KF; BERRIOCHOA MV

2010-02-26

Washington River Protection Solutions, LLC (WRPS) has faced significant project management challenges in managing Davis-Bacon construction work that meets contractually required small business goals. The unique challenge is to provide contracting opportunities to multiple small business constructioin subcontractors while performing high hazard work in a safe and productive manner. Previous to the WRPS contract, construction work at the Hanford Tank Farms was contracted to large companies, while current Department of Energy (DOE) Contracts typically emphasize small business awards. As an integral part of Nuclear Project Management at Hanford Tank Farms, construction involves removal of old equipment and structures and installationmore » of new infrastructure to support waste retrieval and waste feed delivery to the Waste Treatment Plant. Utilizing the optimum construction approach ensures that the contractors responsible for this work are successful in meeting safety, quality, cost and schedule objectives while working in a very hazardous environment. This paper descirbes the successful transition from a traditional project delivery method that utilized a large business general contractor and subcontractors to a new project construction management model that is more oriented to small businesses. Construction has selected the Agency Construction Management Method (John E Schaufelberger, Len Holm, "Management of Construction Projects, A Constructor's Perspective", University of Washington, Prentice Hall 2002). This method was implemented in the first quarter of Fiscal Year 2009 (FY2009), where Construction Management is performed by substantially home office resources from the URS Northwest Office in Richland, Washington. The Agency Method has allowed WRPS to provide proven Construction Managers and Field Leads to mentor and direct small business contractors, thus providing expertise and assurance of a successful project. Construction execution contracts are subcontracted directly by WRPS to small or disadvantaged contractors that are mentored and supported by URS personnel. Each small contractor is mentored and supported utilizing the principles of the Construction Industry Institute (CII) Partnering process. Some of the key mentoring and partnering areas that are explored in this paper are, internal and external safety professional support, subcontractor safety teams and the interface with project and site safety teams, quality assurance program support to facilitate compliance with NQA-1, construction, team roles and responsibilities, work definition for successful fixed price contracts, scheduling and interface with project schedules and cost projection/accruals. The practical application of the CII Partnering principles, with the Construction Management expertise of URS, has led to a highly successful construction model that also meets small business contracting goals.« less

TANK OPERATIONS CONTRACT CONSTRUCTION MANAGEMENT METHODOLOGY UTILIZING THE AGENCY METHOD OF CONSTRUCTION MANAGEMENT TO SAFELY AND EFFECTIVELY COMPLETE NUCLEAR CONSTRUCTION WORK

DOE Office of Scientific and Technical Information (OSTI.GOV)

LESO KF; HAMILTON HM; FARNER M

Washington River Protection Solutions, LLC (WRPS) has faced significant project management challenges in managing Davis-Bacon construction work that meets contractually required small business goals. The unique challenge is to provide contracting opportunities to multiple small business construction subcontractors while performing high hazard work in a safe and productive manner. Previous to the Washington River Protection Solutions, LLC contract, Construction work at the Hanford Tank Farms was contracted to large companies, while current Department of Energy (DOE) Contracts typically emphasize small business awards. As an integral part of Nuclear Project Management at Hanford Tank Farms, construction involves removal of old equipmentmore » and structures and installation of new infrastructure to support waste retrieval and waste feed delivery to the Waste Treatment Plant. Utilizing the optimum construction approach ensures that the contractors responsible for this work are successful in meeting safety, quality, cost and schedule objectives while working in a very hazardous environment. This paper describes the successful transition from a traditional project delivery method that utilized a large business general contractor and subcontractors to a new project construction management model that is more oriented to small businesses. Construction has selected the Agency Construction Management Method. This method was implemented in the first quarter of Fiscal Year (FY) 2009, where Construction Management is performed by substantially home office resources from the URS Northwest Office in Richland, Washington. The Agency Method has allowed WRPS to provide proven Construction Managers and Field Leads to mentor and direct small business contractors, thus providing expertise and assurance of a successful project. Construction execution contracts are subcontracted directly by WRPS to small or disadvantaged contractors that are mentored and supported by DRS personnel. Each small contractor is mentored and supported utilizing the principles of the Construction Industry Institute (CII) Partnering process. Some of the key mentoring and partnering areas that are explored in this paper are, internal and external safety professional support, subcontractor safety teams and the interface with project and site safety teams, quality assurance program support to facilitate compliance with NQA-1, construction, team roles and responsibilities, work definition for successful fixed price contracts, scheduling and interface with project schedules and cost projection/accruals. The practical application of the CII Partnering principles, with the Construction Management expertise of URS, has led to a highly successful construction model that also meets small business contracting goals.« less

22 CFR Appendix A to Part 226 - Contract Provisions

Code of Federal Regulations, 2010 CFR

2010-04-01

... Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT ADMINISTRATION OF ASSISTANCE AWARDS TO U.S. NON-GOVERNMENTAL ORGANIZATIONS Pt. 226, App. A Appendix A to Part 226—Contract Provisions All contracts, awarded by... Organizations and Small Business Firms Under Government Grants, Contracts and Cooperative Agreements,” and any...

48 CFR 1827.303-70 - NASA solicitation provisions and contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false NASA solicitation... COPYRIGHTS Patent Rights Under Government Contracts 1827.303-70 NASA solicitation provisions and contract..., New Technology, in all NASA solicitations and contracts with other than a small business firm or a...

48 CFR 1827.303-70 - NASA solicitation provisions and contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false NASA solicitation... COPYRIGHTS Patent Rights Under Government Contracts 1827.303-70 NASA solicitation provisions and contract..., New Technology, in all NASA solicitations and contracts with other than a small business firm or a...

48 CFR 1827.303-70 - NASA solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true NASA solicitation... COPYRIGHTS Patent Rights Under Government Contracts 1827.303-70 NASA solicitation provisions and contract..., New Technology, in all NASA solicitations and contracts with other than a small business firm or a...

48 CFR 1827.303-70 - NASA solicitation provisions and contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false NASA solicitation... COPYRIGHTS Patent Rights Under Government Contracts 1827.303-70 NASA solicitation provisions and contract..., New Technology, in all NASA solicitations and contracts with other than a small business firm or a...

48 CFR 1827.303-70 - NASA solicitation provisions and contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false NASA solicitation... COPYRIGHTS Patent Rights Under Government Contracts 1827.303-70 NASA solicitation provisions and contract..., New Technology, in all NASA solicitations and contracts with other than a small business firm or a...

48 CFR 970.2770-4 - Contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Patents, Data, and Copyrights 970.2770-4... facility management and operating contract. (b) If the contractor is a nonprofit organization or small business eligible under 35 U.S.C. 200 et seq., to receive title to any inventions under the contract and...

Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction.

PubMed

Huang, Fen; Zhang, Hongkang; Wu, Meng; Yang, Huanghe; Kudo, Makoto; Peters, Christian J; Woodruff, Prescott G; Solberg, Owen D; Donne, Matthew L; Huang, Xiaozhu; Sheppard, Dean; Fahy, John V; Wolters, Paul J; Hogan, Brigid L M; Finkbeiner, Walter E; Li, Min; Jan, Yuh-Nung; Jan, Lily Yeh; Rock, Jason R

2012-10-02

Mucous cell hyperplasia and airway smooth muscle (ASM) hyperresponsiveness are hallmark features of inflammatory airway diseases, including asthma. Here, we show that the recently identified calcium-activated chloride channel (CaCC) TMEM16A is expressed in the adult airway surface epithelium and ASM. The epithelial expression is increased in asthmatics, particularly in secretory cells. Based on this and the proposed functions of CaCC, we hypothesized that TMEM16A inhibitors would negatively regulate both epithelial mucin secretion and ASM contraction. We used a high-throughput screen to identify small-molecule blockers of TMEM16A-CaCC channels. We show that inhibition of TMEM16A-CaCC significantly impairs mucus secretion in primary human airway surface epithelial cells. Furthermore, inhibition of TMEM16A-CaCC significantly reduces mouse and human ASM contraction in response to cholinergic agonists. TMEM16A-CaCC blockers, including those identified here, may positively impact multiple causes of asthma symptoms.

Marine Corps Installations National Capital RegionRegional Contracting Office Generally Implemented Recommendations

DTIC Science & Technology

2016-07-29

Corps Installations National Capital Region–Regional Contracting Office Generally Implemented Recommendations J U LY 2 9 , 2 0 1 6 Report No...Installations National Capital Region–Regional Contracting Office Generally Implemented Recommendations Objective We determined whether the Marine...Corps Regional Contracting Office–National Capital Region implemented the recommendations in Report No. DODIG-2015-095, “Small Business Contracting

13 CFR 125.21 - Are there SDVO contracting opportunities at or below the simplified acquisition threshold?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Are there SDVO contracting opportunities at or below the simplified acquisition threshold? 125.21 Section 125.21 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS Contracting with SDVO SBCs § 125.21 Are there SDVO contracting opportunities...

13 CFR 125.21 - Are there SDVO contracting opportunities at or below the simplified acquisition threshold?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Are there SDVO contracting opportunities at or below the simplified acquisition threshold? 125.21 Section 125.21 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS Contracting with SDVO SBCs § 125.21 Are there SDVO contracting opportunities...

13 CFR 125.21 - Are there SDVO contracting opportunities at or below the simplified acquisition threshold?

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Are there SDVO contracting opportunities at or below the simplified acquisition threshold? 125.21 Section 125.21 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS Contracting with SDVO SBCs § 125.21 Are there SDVO contracting opportunities...

13 CFR 125.21 - Are there SDVO contracting opportunities at or below the simplified acquisition threshold?

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Are there SDVO contracting opportunities at or below the simplified acquisition threshold? 125.21 Section 125.21 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENT CONTRACTING PROGRAMS Contracting with SDVO SBCs § 125.21 Are there SDVO contracting opportunities...

Stretch-induced contraction in pulmonary arteries.

PubMed

Kulik, T J; Evans, J N; Gamble, W J

1988-12-01

Stretch stimulates contraction of systemic blood vessels, but the response has not been described in pulmonary vessels. To determine whether pulmonary arteries contract when stretched, isolated cylindrical segments of pulmonary arteries were suspended between two parallel wires, stretched, and the active force was generated in response to stretch measured. Eighty-nine percent of segments from small (in situ diameter less than 1,000 microns) feline pulmonary arteries contracted when stretched, and in 65% of these the magnitude of stretch was related to the magnitude of contraction. Large (in situ diameter greater than or equal to 1,000 microns) feline pulmonary arteries did not contract with stretch. Multiple, rapidly repeated stretches resulted in a diminution of active force development. Stretch-induced contraction required external Ca2+ and was abolished by diltiazem (10 microns), but it was not affected by phenoxybenzamine, phentolamine, diethylcarbamazine, or mechanical removal of endothelium. Indomethacin blunted but did not abolish stretch-induced contraction, an effect that may have been nonspecific. This study suggests that stretch can act, probably directly, on smooth muscle in small feline pulmonary arteries to elicit contraction and that it may be a determinant of pulmonary vascular tone. In addition, feline pulmonary arteries are suitable for the in vitro study of stretch-induced contraction.

Small-Gap Flows

DTIC Science & Technology

1984-04-01

I TV N 4 NAVAL ARCIETUR & OFFSHORE ENGINEERING SMALL- GAP FLOWSti E 0.TUCK01 REPORT NO- M!AOL 34-1 CONTRACT NJU1-𔃾-K-0026 APRIL 1984 let.? UNIVERSMn...34’OF CALIFORNIA# BERKELEY, CA 5.1720 ft (45 642-141 SMALL- GAP FLOWS BY E. 0. TUCK REPORT No. NAUE 84-1 CONTRACT N00014-84-K-OU26 APRIL i984...34small- gap " theme.Chapters 1-4 were originally presented in the form of a lecture series in the Department of Naval Architecture and Offshore

NASA Small Business Innovation Research Program. Composite List of Projects, 1983 to 1989

NASA Technical Reports Server (NTRS)

1990-01-01

The NASA SBIR Composite List of Projects, 1983 to 1989, includes all projects that have been selected for support by the Small Business Innovation Research (SBIR) Program of NASA. The list describes 1232 Phase 1 and 510 Phase 2 contracts that had been awarded or were in negotiation for award in August 1990. The main body is organized alphabetically by name of the small businesses. Four indexes cross-reference the list. The objective of this listing is to provide information about the SBIR program to anyone concerned with NASA research and development activities.

48 CFR 19.804-2 - Agency offering.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Agency offering. 19.804-2... PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a) Program) 19... following information applicable to each prospective contract: (1) A description of the work to be performed...

Identification of the Slow Wave of Small Bowel Myoelectrical Activity by Surface Recording

DTIC Science & Technology

2001-10-25

recording of myoelectrical activity (Fig. 1), which underlies intestinal smooth muscle contraction . In effect, the relation between intestinal mechanical...Martínez-de-Juan, J. Saiz, M. Meseguer, J.L. Ponce “Small bowel motility: relationship between smooth muscle contraction and electroenterogram signal”, Med

Defense Small Business Innovation Research Program (SBIR). Volume 1. Army Projects, Abstracts of Phase 1 Awards from FY 1989 SBIR Solicitation

DTIC Science & Technology

1990-04-01

CONTRACT NUMBER: WILLIAM R BELCHER TITLE: SORBENTS FOR DECONTAMINATION OF CHEMICAL WARFARE AGENTS TOIC# 2 OFFICE: CRDEC IDENT#: 33401 SMALL BUSINESS...INDUSTRIES PO BOX 4338 - 4 LEONARD ST METUCHEN, NJ 08340 CONTRACT NUMBER: DR ASIT ROY TITLE: NOVEL ACTIVE SORBENTS FOR DECONTAMINATION OF CHEMICAL WARFARE AGE...DEFERRED TO PHASE II. BELTRAN INC 1133 E 35TH ST BROOKLYN, NY 11210 CONTRACT NUMBER: DR CONSTANCE SIMO TITLE: CONTROLLED CHEMICAL MODIFICATION OF

Particle Acceleration via Reconnection Processes in the Supersonic Solar Wind

NASA Astrophysics Data System (ADS)

Zank, G. P.; le Roux, J. A.; Webb, G. M.; Dosch, A.; Khabarova, O.

2014-12-01

An emerging paradigm for the dissipation of magnetic turbulence in the supersonic solar wind is via localized small-scale reconnection processes, essentially between quasi-2D interacting magnetic islands. Charged particles trapped in merging magnetic islands can be accelerated by the electric field generated by magnetic island merging and the contraction of magnetic islands. We derive a gyrophase-averaged transport equation for particles experiencing pitch-angle scattering and energization in a super-Alfvénic flowing plasma experiencing multiple small-scale reconnection events. A simpler advection-diffusion transport equation for a nearly isotropic particle distribution is derived. The dominant charged particle energization processes are (1) the electric field induced by quasi-2D magnetic island merging and (2) magnetic island contraction. The magnetic island topology ensures that charged particles are trapped in regions where they experience repeated interactions with the induced electric field or contracting magnetic islands. Steady-state solutions of the isotropic transport equation with only the induced electric field and a fixed source yield a power-law spectrum for the accelerated particles with index α = -(3 + MA )/2, where MA is the Alfvén Mach number. Considering only magnetic island contraction yields power-law-like solutions with index -3(1 + τ c /(8τdiff)), where τ c /τdiff is the ratio of timescales between magnetic island contraction and charged particle diffusion. The general solution is a power-law-like solution with an index that depends on the Alfvén Mach number and the timescale ratio τdiff/τ c . Observed power-law distributions of energetic particles observed in the quiet supersonic solar wind at 1 AU may be a consequence of particle acceleration associated with dissipative small-scale reconnection processes in a turbulent plasma, including the widely reported c -5 (c particle speed) spectra observed by Fisk & Gloeckler and Mewaldt et al.

Particle acceleration via reconnection processes in the supersonic solar wind

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zank, G. P.; Le Roux, J. A.; Webb, G. M.

An emerging paradigm for the dissipation of magnetic turbulence in the supersonic solar wind is via localized small-scale reconnection processes, essentially between quasi-2D interacting magnetic islands. Charged particles trapped in merging magnetic islands can be accelerated by the electric field generated by magnetic island merging and the contraction of magnetic islands. We derive a gyrophase-averaged transport equation for particles experiencing pitch-angle scattering and energization in a super-Alfvénic flowing plasma experiencing multiple small-scale reconnection events. A simpler advection-diffusion transport equation for a nearly isotropic particle distribution is derived. The dominant charged particle energization processes are (1) the electric field induced bymore » quasi-2D magnetic island merging and (2) magnetic island contraction. The magnetic island topology ensures that charged particles are trapped in regions where they experience repeated interactions with the induced electric field or contracting magnetic islands. Steady-state solutions of the isotropic transport equation with only the induced electric field and a fixed source yield a power-law spectrum for the accelerated particles with index α = –(3 + M{sub A} )/2, where M{sub A} is the Alfvén Mach number. Considering only magnetic island contraction yields power-law-like solutions with index –3(1 + τ {sub c}/(8τ{sub diff})), where τ {sub c}/τ{sub diff} is the ratio of timescales between magnetic island contraction and charged particle diffusion. The general solution is a power-law-like solution with an index that depends on the Alfvén Mach number and the timescale ratio τ{sub diff}/τ {sub c}. Observed power-law distributions of energetic particles observed in the quiet supersonic solar wind at 1 AU may be a consequence of particle acceleration associated with dissipative small-scale reconnection processes in a turbulent plasma, including the widely reported c {sup –5} (c particle speed) spectra observed by Fisk and Gloeckler and Mewaldt et al.« less

Small Business Innovations

NASA Technical Reports Server (NTRS)

1994-01-01

A Small Business Innovation Research (SBIR) contract resulted in a series of commercially available lasers, which have application in fiber optic communications, difference frequency generation, fiber optic sensing and general laboratory use. Developed under a Small Business Innovation Research (SBIR) contract, the Phase Doppler Particles Analyzer is a non-disruptive, highly accurate laser-based method of determining particle size, number density, trajectory, turbulence and other information about particles passing through a measurement probe volume. The system consists of an optical transmitter and receiver, signal processor and computer with data acquisition and analysis software. A variety of systems are offered for applications including spray characterization for paint, and agricultural and other sprays. The Microsizer, a related product, is used in medical equipment manufacturing and analysis of contained flows. High frequency components and subsystems produced by Millitech Corporation are marketed for both research and commercial use. These systems, which operate in the upper portion of the millimeter wave, resulted from a number of Small Business Innovation Research (SBIR) projects. By developing very high performance mixers and multipliers, the company has advanced the state of the art in sensitive receiver technology. Components are used in receivers and transceivers for monitoring chlorine monoxides, ozone, in plasma characterization and in material properties characterization.

76 FR 77510 - Applications for New Awards; Small Business Innovation Research Program (SBIR)-Phase I

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

..., including projects leading to the manufacture of such items as artificial intelligence or information... obtain a copy of the application package in an accessible format (e.g., braille, large print, audiotape...., braille, large print, audiotape, or compact disc) by contacting the Grants and Contracts Services Team, U...

Effect of tachykinins in small human airways.

PubMed

Frossard, N; Barnes, J

1991-07-01

We have compared the contractile responses of substance P (SP) and neurokinin A (NKA) to that of the non degradable muscarinic agonist, carbachol, in small and large human airways in vitro. We have also investigated the effects of the neutral endopeptidase (NEP) inhibitor, thiorphan (100 microM) on these responses. NKA contracted large and small airways to a different extent (56% vs 92% of carbachol maximal contraction, respectively). NKA was significantly less potent in large vs small bronchi (EC50 = 150 +/- 15 vs 12 +/- 5 nM respectively, p less than 0.05). SP had a lower contractile effect in large (26% carbachol maximum) and small airways (59%) with EC50 values higher than 0.5 microM. The enkephalinase inhibitor thiorphan shifted the concentration-response curve to NKA to the left in large (EC50 = 35.2 +/- 8.2 nM) and small bronchi (EC50 = 2.8 +/- 1.3 nM, p less than 0.02). This shift was associated with an increase in the maximal contraction to NKA (75% in large vs 123% in small bronchi). The amplitude of contraction to SP was also potentiated in large (45%) and in smaller bronchi (101%). In conclusion, we have demonstrated that NKA has a significantly greater constrictor effect than a cholinergic agent in more peripheral human airways in vitro. This suggests that non cholinergic constrictor pathways are more likely to be important in more peripheral airways.

Energy service contracts in regional engineering center for small and medium businesses

NASA Astrophysics Data System (ADS)

Gil'manshin, I. R.; Kashapov, N. F.

2014-12-01

The analysis of the energy service contracts development in Russia is given in the article. The role of the Complex learning centres in the field of energy efficiency in the promotion of energy service contracts is described. The reasons of constraining the development of energy service contracts are described.

7 CFR 4280.115 - Construction planning and performing development.

Code of Federal Regulations, 2010 CFR

2010-01-01

... projects as applicable. For contracts of $200,000 or less, the simple contract method, as specified in... warranty documents. (e) Simple contract method. The simple contract method may be used for small projects... Agency and may be used only if they are customarily used in the area and protect the interest of the...

13 CFR 125.17 - Who decides if a contract opportunity for SDVO competition exists?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Who decides if a contract opportunity for SDVO competition exists? 125.17 Section 125.17 Business Credit and Assistance SMALL BUSINESS... opportunity for SDVO competition exists? The contracting officer for the contracting activity decides if a...

Effect of prolonged general anesthesia with sevoflurane and laparoscopic surgery on gastric and small bowel propulsive motility and pH in dogs.

PubMed

Boscan, Pedro; Cochran, Shannon; Monnet, Eric; Webb, Craig; Twedt, David

2014-01-01

To determine if general anesthesia with sevoflurane and laparoscopic surgery changed gastric and small bowel propulsive motility or pH in dogs. Prospective, controlled trial. Twelve, 19-24 months old, female, Treeing Walker Hound dogs, weighing 23-30 kg. Dogs were anesthetized for a median of 8.5 hours during another study to determine the minimum alveolar concentration of sevoflurane using a visceral stimulus. Gastric and small bowel motility were determined using a sensor capsule that measures pressure, pH and temperature. Gastric transit time and motility index were calculated. For 8/12 dogs, gastric motility, pH and transit time were measured. In 4/12 dogs, small bowel motility and pH were measured. Anesthesia decreased gastric and small bowel motility but did not change luminal pH. Mean gastric contraction force decreased from median (range) 11 (8-20) to 3 (1-10) mmHg (p < 0.01) and gastric motility index decreased from 0.63 (0-1.58) to 0 (0-0.31; p = 0.01). Frequency of contractions did not change, 3.7 (1.6-4.4) versus 2.8 (0.1-5.1) contractions minute(-1) (p = 0.1). Gastric motility returned to normal 12-15 hours following anesthesia. Gastric emptying was prolonged from 12 (5.3-16) to 49 (9.75-56.25) hours (p < 0.01). Mean small bowel contraction force decreased from 34 (24-37) to 3 (0.9-17) mmHg (p < 0.02) and motility index decreased from 3.75 (1-4.56) to 0 (0-1.53; p = 0.02). Frequency of contractions did not change, 0.5 (0.3-1.4) versus 1.4 (0.3-4.6) contractions minute(-1) (p = 0.11). Small bowel motility returned within 2 hours after anesthesia. Laparoscopy did not result in changes to gastric or small bowel parameters beyond those produced by general anesthesia. The force of gastric and small bowel contractions decreased during sevoflurane anesthesia for laparoscopy. Although gastric motility returned to normal within 12-15 hours the impairment of gastric emptying lasted 30-40 hours, predisposing dogs to postoperative ileus. © 2013 Association of Veterinary Anaesthetists and the American College of Veterinary Anesthesia and Analgesia.

48 CFR 2819.7001 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... BUSINESS PROGRAMS Forecasts of Expected Contract Opportunities 2819.7001 General. Section 501 of Public Law 100-656, the Business Opportunity Development Reform Act of 1988, requires executive agencies having... expected contract opportunities, or classes of contract opportunities that small business concerns...

12 CFR 4.62 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND RELEASE OF INFORMATION, CONTRACTING OUTREACH PROGRAM, POST-EMPLOYMENT RESTRICTIONS FOR SENIOR EXAMINERS Minority- , Women- , and Individuals With Disabilities-Owned Business Contracting Outreach Program; Contracting for Goods and Services § 4.62 Definitions. (a) Minority- and/or women-owned (small and large...

Developing Novel Therapeutic Approaches in Small Cell Lung Carcinoma Using Genetically Engineered Mouse Models and Human Circulating Tumor Cells

DTIC Science & Technology

2014-10-01

AD_________________ Award Number: W81XWH-13-1-0325 TITLE: Developing Novel Therapeutic Approaches in Small Cell Lung Carcinoma Using ...Genetically Engineered Mouse Models and Human Circulating Tumor Cells PRINCIPAL INVESTIGATOR: Jeffrey Engelman MD PhD CONTRACTING ORGANIZATION ...Novel Therapeutic Approaches in Small Cell Lung 5a. CONTRACT NUMBER W81XWH-13-1-0325 Carcinoma Using Genetically Engineered Mouse Models and 5b

48 CFR 719.273-1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS The U.S. Agency for International Development (USAID) Mentor-Protégé Program 719.273-1 Purpose. The USAID Mentor-Protégé Program is designed to assist small business... capabilities to perform contracts and sub-contracts for USAID and other Federal agencies. The Mentor-Protégé...

48 CFR 252.227-7025 - Limitations on the use or disclosure of government-furnished information marked with restrictive...

Code of Federal Regulations, 2010 CFR

2010-10-01

... Software and Noncommercial Computer Software Documentation clause of this contract. (3) For Small Business... Rights in Noncommercial Technical Data and Computer Software—Small Business Innovative Research (SBIR) Program clause of this contract. (b) Technical data or computer software provided to the Contractor as...

48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or computer software will be generated during performance of contracts under the SBIR program. (b) Under the clause at 252.227-7018, the Government obtains SBIR data rights in technical data and computer software...

48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or computer software will be generated during performance of contracts under the SBIR program. (b) Under the clause at 252.227-7018, the Government obtains SBIR data rights in technical data and computer software...

48 CFR 19.707 - The Small Business Administration's role in carrying out the program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Administration's role in carrying out the program. 19.707 Section 19.707 Federal Acquisition Regulations System... Subcontracting Program 19.707 The Small Business Administration's role in carrying out the program. (a) Under the... nature; and (4) Evaluate compliance with subcontracting plans, either on a contract-by-contract basis, or...

13 CFR 127.502 - How will SBA identify and provide notice of the designated industries?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false How will SBA identify and provide notice of the designated industries? 127.502 Section 127.502 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT ASSISTANCE PROCEDURES Federal Contract...

48 CFR 619.804-3-70 - SBA acceptance under MOUs for acquisitions exceeding $100,000.

Code of Federal Regulations, 2010 CFR

2010-10-01

... System DEPARTMENT OF STATE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting with the Small Business Administration (The 8(a) Program) 619.804-3-70 SBA acceptance under MOUs for acquisitions... contracting agency in writing within five working days of receipt of the offer. (b) The SBA may request, and...

13 CFR 125.6 - Prime contractor performance requirements (limitations on subcontracting).

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Prime contractor performance requirements (limitations on subcontracting). 125.6 Section 125.6 Business Credit and Assistance SMALL BUSINESS... subcontracting). (a) In order to be awarded a full or partial small business set-aside contract, an 8(a) contract...

48 CFR 1.601 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... In some agencies, a relatively small number of high level officials are designated contracting officers solely by virtue of their positions. Contracting officers below the level of a head of a... REGULATIONS SYSTEM Career Development, Contracting Authority, and Responsibilities 1.601 General. (a) Unless...

A Comparison of the Small and Disadvantaged Business Utilization Specialists (SADBUS’) Role at Navy Regional Contracting Center (NRCC) philadelphia, Pennsylvania and Navy Regional Contracting Center (NRCC) San Diego, California Detachment Long Beach

DTIC Science & Technology

1991-12-31

NAVAL POSTGRADUATE SCHOOL Monterey, California ITan THESIS A comparison of the Small and Disadvantaged Business Utilization Specialists (SADBUS...8217A -Approved for public release: distribution is unlimited A Comparison of the small and Disadvantaged Business Utilization-Specialists (SADBUSI) Role...I D TIC ufst Spcati1 ABSTRACT This thesis analyzes the role of the Small and Disadvantaged Business Utii4zati6n Specialist (SADBUS) at the Navy

13 CFR 126.609 - What must the contracting officer do if a contracting opportunity does not exist for competition...

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What must the contracting officer do if a contracting opportunity does not exist for competition among qualified HUBZone SBCs? 126.609 Section 126.609 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Contractual...

'Laguna Hollow'Undisturbed

NASA Technical Reports Server (NTRS)

2004-01-01

This image shows the patch of soil at the bottom of the shallow depression dubbed 'Laguna Hollow' where the Mars Exploration Rover Spirit will soon begin trenching. Scientists are intrigued by the clustering of small pebbles and the crack-like fine lines, which indicate a coherent surface that expands and contracts. A number of processes can cause materials to expand and contract, including cycles of heating and cooling; freezing and thawing; and rising and falling of salty liquids within a substance. This false-color image was created using the blue, green and infrared filters of the rover's panoramic camera. Scientists chose this particular combination of filters to enhance the heterogeneity of the martian soil.

48 CFR 32.403 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., research, or development work with nonprofit educational or research institutions. (b) Contracts solely for... could not be expected to suitably administer a guaranteed loan. (g) Contracts with small business... contract financing method for both the Government and the contractor. [48 FR 42328, Sept. 19, 1983, as...

Electronic spreadsheet vs. manual payroll.

PubMed

Kiley, M M

1991-01-01

Medical groups with direct employees must employ someone or contract with a company to compute payroll, writes Michael Kiley, Ph.D., M.P.H. However, many medical groups, including small ones, own a personal or minicomputer to handle accounts receivable. Kiley explains, in detail, how this same computer and a spreadsheet program also can be used to perform payroll functions.

Simulation Accelerator

NASA Technical Reports Server (NTRS)

1998-01-01

Under a NASA SBIR (Small Business Innovative Research) contract, (NAS5-30905), EAI Simulation Associates, Inc., developed a new digital simulation computer, Starlight(tm). With an architecture based on the analog model of computation, Starlight(tm) outperforms all other computers on a wide range of continuous system simulation. This system is used in a variety of applications, including aerospace, automotive, electric power and chemical reactors.

76 FR 40798 - Antidrug and Alcohol Misuse Prevention Programs for Personnel Engaged in Specified Aviation...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-12

... includes contractors and subcontractors. Contracting companies have two testing options: Option one is for... case today and as such, there are no alternatives to the final rule that could have been considered and... stations would be classified as small business under NAICS 488180, the FAA reviewed a recent study...

Design Tool

NASA Technical Reports Server (NTRS)

1993-01-01

Developed under a Small Business Innovation Research (SBIR) contract, RAMPANT is a CFD software package for computing flow around complex shapes. The package is flexible, fast and easy to use. It has found a great number of applications, including computation of air flow around a Nordic ski jumper, prediction of flow over an airfoil and computation of the external aerodynamics of motor vehicles.

JPRS Report, Science & Technology, Europe, Economic Competitiveness.

DTIC Science & Technology

1991-08-09

in the form of proportional subsidies for research contracts concluded with large companies. For contracts concluded with small - and medium ...special programs to help small - and medium -sized enterprises (SME’s) that carry out research work , and to foster the growth of an innovative SME base...process of being developed. MEDIA DUEMILA: In the past, the EEC relied on

There's Gold in Those Contracts

ERIC Educational Resources Information Center

Diaz, Russell

2009-01-01

In 2006, when the author joined the staff at Dominican College (New York), he discovered that the network, computers, and IT contracts were in sorry shape. He also found that this kind of condition is common in small colleges. Such a state of affairs is usually brought about by the unrelenting demands placed on small IT staffs. IT staffers at…

13 CFR 127.501 - How will SBA determine the industries that are eligible for EDWOSB or WOSB requirements?

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false How will SBA determine the industries that are eligible for EDWOSB or WOSB requirements? 127.501 Section 127.501 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT PROGRAM Federal Contract...

13 CFR 127.501 - How will SBA determine the industries that are eligible for EDWOSB or WOSB requirements?

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false How will SBA determine the industries that are eligible for EDWOSB or WOSB requirements? 127.501 Section 127.501 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT PROGRAM Federal Contract...

13 CFR 127.501 - How will SBA determine the industries that are eligible for EDWOSB or WOSB requirements?

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false How will SBA determine the industries that are eligible for EDWOSB or WOSB requirements? 127.501 Section 127.501 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT PROGRAM Federal Contract...

Cross-talk between cardiac muscle and coronary vasculature.

PubMed

Westerhof, Nico; Boer, Christa; Lamberts, Regis R; Sipkema, Pieter

2006-10-01

The cardiac muscle and the coronary vasculature are in close proximity to each other, and a two-way interaction, called cross-talk, exists. Here we focus on the mechanical aspects of cross-talk including the role of the extracellular matrix. Cardiac muscle affects the coronary vasculature. In diastole, the effect of the cardiac muscle on the coronary vasculature depends on the (changes in) muscle length but appears to be small. In systole, coronary artery inflow is impeded, or even reversed, and venous outflow is augmented. These systolic effects are explained by two mechanisms. The waterfall model and the intramyocardial pump model are based on an intramyocardial pressure, assumed to be proportional to ventricular pressure. They explain the global effects of contraction on coronary flow and the effects of contraction in the layers of the heart wall. The varying elastance model, the muscle shortening and thickening model, and the vascular deformation model are based on direct contact between muscles and vessels. They predict global effects as well as differences on flow in layers and flow heterogeneity due to contraction. The relative contributions of these two mechanisms depend on the wall layer (epi- or endocardial) and type of contraction (isovolumic or shortening). Intramyocardial pressure results from (local) muscle contraction and to what extent the interstitial cavity contracts isovolumically. This explains why small arterioles and venules do not collapse in systole. Coronary vasculature affects the cardiac muscle. In diastole, at physiological ventricular volumes, an increase in coronary perfusion pressure increases ventricular stiffness, but the effect is small. In systole, there are two mechanisms by which coronary perfusion affects cardiac contractility. Increased perfusion pressure increases microvascular volume, thereby opening stretch-activated ion channels, resulting in an increased intracellular Ca2+ transient, which is followed by an increase in Ca2+ sensitivity and higher muscle contractility (Gregg effect). Thickening of the shortening cardiac muscle takes place at the expense of the vascular volume, which causes build-up of intracellular pressure. The intracellular pressure counteracts the tension generated by the contractile apparatus, leading to lower net force. Therefore, cardiac muscle contraction is augmented when vascular emptying is facilitated. During autoregulation, the microvasculature is protected against volume changes, and the Gregg effect is negligible. However, the effect is present in the right ventricle, as well as in pathological conditions with ineffective autoregulation. The beneficial effect of vascular emptying may be reduced in the presence of a stenosis. Thus cardiac contraction affects vascular diameters thereby reducing coronary inflow and enhancing venous outflow. Emptying of the vasculature, however, enhances muscle contraction. The extracellular matrix exerts its effect mainly on cardiac properties rather than on the cross-talk between cardiac muscle and coronary circulation.

PAR-2 agonists induce contraction of murine small intestine through neurokinin receptors.

PubMed

Zhao, Aiping; Shea-Donohue, Terez

2003-10-01

Protease-activated receptor-2 (PAR-2) is a G protein-coupled receptor and is expressed throughout the gut. It is well known that PAR-2 participates in the regulation of gastrointestinal motility; however, the results are inconsistent. The present study investigated the effect and mechanism of PAR-2 activation on murine small intestinal smooth muscle function in vitro. Both trypsin and PAR-2-activating peptide SLIGRL induced a small relaxation followed by a concentration-dependent contraction. The sensitivity to trypsin was greater than that to SLIGRL (EC50 = 0.03 vs. 40 microM), but maximal responses were similar (12.3 +/- 1.6 vs. 13.7 +/- 1.3 N/cm2). Trypsin-evoked contraction (1 microM) exhibited a rapid desensitization, whereas the desensitization of response to SLIGRL was less even at high concentration (50 microM). Atropine had no effect on PAR-2 agonist-induced contractions. In contrast, TTX and capsaicin significantly attenuated those contractions, implicating a neurogenic mechanism that may involve capsaicin-sensitive sensory nerves. Furthermore, contractions induced by trypsin and SLIGRL were reduced by neurokinin receptor NK1 antagonist SR-140333 or NK2 antagonist SR-48968 alone or were further reduced by combined application of SR-140333 and SR-48968, indicating the involvement of neurokinin receptors. In addition, desensitizing neurokinin receptors with substance P and/or neurokinin A decreased the PAR-2 agonist-evoked contraction. We concluded that PAR-2 agonists induced a contraction of murine intestinal smooth muscle that was mediated by nerves. The excitatory effect is also dependent on sensory neural pathways and requires both NK1 and NK2 receptors.

48 CFR 719.271-3 - USAID contracting officers.

Code of Federal Regulations, 2012 CFR

2012-10-01

... contracts to SDB for screening (see 719.271-6); (h) Taking action to assure that unnecessary qualifications... determinations, the contracting officer shall consider the recommendations, if any, of SDB together with the... small minority business enterprises, to SDB for information and advice; (k) Promoting increased...

48 CFR 719.271-3 - USAID contracting officers.

Code of Federal Regulations, 2011 CFR

2011-10-01

... contracts to SDB for screening (see 719.271-6); (h) Taking action to assure that unnecessary qualifications... determinations, the contracting officer shall consider the recommendations, if any, of SDB together with the... small minority business enterprises, to SDB for information and advice; (k) Promoting increased...

48 CFR 719.271-3 - USAID contracting officers.

Code of Federal Regulations, 2014 CFR

2014-10-01

... contracts to SDB for screening (see 719.271-6); (h) Taking action to assure that unnecessary qualifications... determinations, the contracting officer shall consider the recommendations, if any, of SDB together with the... small minority business enterprises, to SDB for information and advice; (k) Promoting increased...

48 CFR 719.271-3 - USAID contracting officers.

Code of Federal Regulations, 2013 CFR

2013-10-01

... contracts to SDB for screening (see 719.271-6); (h) Taking action to assure that unnecessary qualifications... determinations, the contracting officer shall consider the recommendations, if any, of SDB together with the... small minority business enterprises, to SDB for information and advice; (k) Promoting increased...

78 FR 77352 - Small Business Policy

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-23

... Associate Administrator for the Office of Small Business Programs shall nominate a qualified individual in... Small Business Programs shall assign a Small Business Technical Advisor to each contracting activity...

Effects of gap junction inhibition on contraction waves in the murine small intestine in relation to coupled oscillator theory.

PubMed

Parsons, Sean P; Huizinga, Jan D

2015-02-15

Waves of contraction in the small intestine correlate with slow waves generated by the myenteric network of interstitial cells of Cajal. Coupled oscillator theory has been used to explain steplike gradients in the frequency (frequency plateaux) of contraction waves along the length of the small intestine. Inhibition of gap junction coupling between oscillators should lead to predictable effects on these plateaux and the wave dislocation (wave drop) phenomena associated with their boundaries. It is these predictions that we wished to test. We used a novel multicamera diameter-mapping system to measure contraction along 25- to 30-cm lengths of murine small intestine. There were typically two to three plateaux per length of intestine. Dislocations could be limited to the wavefronts immediately about the terminated wave, giving the appearance of a three-pronged fork, i.e., a fork dislocation; additionally, localized decreases in velocity developed across a number of wavefronts, ending with the terminated wave, which could appear as a fork, i.e., slip dislocations. The gap junction inhibitor carbenoxolone increased the number of plateaux and dislocations and decreased contraction wave velocity. In some cases, the usual frequency gradient was reversed, with a plateau at a higher frequency than its proximal neighbor; thus fork dislocations were inverted, and the direction of propagation was reversed. Heptanol had no effect on the frequency or velocity of contractions but did reduce their amplitude. To understand intestinal motor patterns, the pacemaker network of the interstitial cells of Cajal is best evaluated as a system of coupled oscillators. Copyright © 2015 the American Physiological Society.

An Open Door and a Leg Up: Increasing Service-Disabled Veteran-Owned Small Business (SDVOSB) Participation in Defense Contracting Through Simplified Acquisitions (Briefing Charts)

DTIC Science & Technology

2015-05-01

An Open Door and a Leg Up : Increasing Service-Disabled Veteran-Owned Small Business (SDVOSB) Participation in Defense Contracting Through...to 00-00-2015 4. TITLE AND SUBTITLE An Open Door and a Leg Up : Increasing Service-Disabled Veteran-Owned Small Business (SDVOSB) Participation in...4/1999 Rejection of Access to 8(a) Program in HR 1460 Veterans Entrepreneurship and Benefits Improvement Act of 2003 6/5/2003 Unutilized

48 CFR 927.303 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... is a domestic small business or nonprofit organization as defined at (FAR) 48 CFR 27.301, except... contracts for the management and operation of DOE laboratories and production facilities. (b) DOE shall not... its rights in an identified invention pursuant to 10 CFR part 784, contracting officers shall consult...

48 CFR 27.306 - Licensing background patent rights to third parties.

Code of Federal Regulations, 2012 CFR

2012-10-01

... patent rights to third parties. 27.306 Section 27.306 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights under Government Contracts 27.306 Licensing background patent rights to third parties. (a) A contract with a small...

48 CFR 27.306 - Licensing background patent rights to third parties.

Code of Federal Regulations, 2010 CFR

2010-10-01

... patent rights to third parties. 27.306 Section 27.306 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights under Government Contracts 27.306 Licensing background patent rights to third parties. (a) A contract with a small...

48 CFR 970.1907 - Subcontracting with Small Business, Small Disadvantaged Business and Woman-Owned Small Business...

Code of Federal Regulations, 2010 CFR

2010-10-01

... Business, Small Disadvantaged Business and Woman-Owned Small Business Concerns. 970.1907 Section 970.1907... MANAGEMENT AND OPERATING CONTRACTS Small, Small Disadvantaged and Women-Owned Small Business Concerns 970.1907 Subcontracting with Small Business, Small Disadvantaged Business and Woman-Owned Small Business...

13 CFR 125.15 - What requirements must an SDVO SBC meet to submit an offer on a contract?

Code of Federal Regulations, 2010 CFR

2010-01-01

... corresponding to the NAICS code assigned to the contract, provided: (A) For a procurement having a revenue-based... to the contract; or (B) For a procurement having an employee-based size standard, the procurement... specific contract: (1) It is an SDVO SBC; (2) It is small under the NAICS code assigned to the procurement...

48 CFR 19.505 - Rejecting Small Business Administration recommendations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... to the appropriate SBA representative within 5 working days of the contracting officer's receipt of... contracting activity (or designee) within 2 working days after receiving the notice. The head of the... representative within 7 working days. Pending issuance of a decision to the SBA representative, the contracting...

Frozen Smoke

NASA Technical Reports Server (NTRS)

1998-01-01

Under a NASA SBIR (Small Business Innovative Research) contract with Johnson Space Center, Aspen Systems developed aerogel-based superinsulation. This super-insulation is an innovative, flexible cryogenic insulation with extremely low thermal conductivity. Potential commercial uses include cryogenic applications in the transportation, storage and transfer of cryogens; near room-temperature applications such as refrigerator insulation; and elevated temperature applications such as insulations for high- temperature industrial processes and furnaces.

Mobile Skilled Workers: Making the Most of an Untapped Rural Community Resource

ERIC Educational Resources Information Center

Kilpatrick, Sue; Johns, Susan; Vitartas, Peter; Homisan, Martin

2011-01-01

Many small rural communities have a flow of skilled people through the community, including employees from the government, non government and private sectors on fixed-term contracts, and a range of professionals, often attracted by amenity and seeking a sea change or tree change. The aim of the study reported in this paper was to investigate how…

48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

Code of Federal Regulations, 2013 CFR

2013-10-01

...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

Code of Federal Regulations, 2014 CFR

2014-10-01

...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

Code of Federal Regulations, 2011 CFR

2011-10-01

...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

Code of Federal Regulations, 2012 CFR

2012-10-01

...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

48 CFR 2019.705 - Responsibilities of the contracting officer under the subcontracting assistance program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Regulations System NUCLEAR REGULATORY COMMISSION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Subcontracting With Small Business, Small Disadvantaged Business, and Women-Owned Small Business Concerns 2019.705...

48 CFR 319.705 - Responsibilities of the Contracting Officer under the subcontracting assistance program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Regulations System HEALTH AND HUMAN SERVICES SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Subcontracting With Small Business, Small Disadvantaged Business, and Women-Owned Small Business Concerns 319.705...

Laser Doppler vibrometry measurement of the mechanical myogram

NASA Astrophysics Data System (ADS)

Rohrbaugh, John W.; Sirevaag, Erik J.; Richter, Edward J.

2013-12-01

Contracting muscles show complex dimensional changes that include lateral expansion. Because this expansion process is intrinsically vibrational, driven by repetitive actions of multiple motor units, it can be sensed and quantified using the method of Laser Doppler Vibrometry (LDV). LDV has a number of advantages over more traditional mechanical methods based on microphones and accelerometers. The LDV mechanical myogram from a small hand muscle (the first dorsal interosseous) was studied under conditions of elastic loading applied to the tip of the abducted index finger. The LDV signal was shown to be related systematically to the level of force production, and to compare favorably with conventional methods for sensing the mechanical and electrical aspects of muscle contraction.

Competitiveness in the Services Sector: Understanding the Contracting Data

DTIC Science & Technology

2012-09-01

Retrieved from http://www.acq.osd.mil/osbp/sbir/sb/eligibility.shtml Denes, T. A. (1997). Do small business set - asides increase the cost of...comprises small businesses , while TechAmerica and the Coalition for Government Procurement primarily comprise large firms. Our discussions with... procurement auctions . Lamm, D. V. (1987). Why firms refuse DOD business : an analysis of rationale. National Contract Management Journal , 21 (Winter

But I'm an engineer—not a contracts lawyer!

NASA Astrophysics Data System (ADS)

Warner, Mark; Bass, Harvey

2012-09-01

Industrial partners, commercial vendors, and subsystem contractors play a large role in the design and construction of modern telescopes. Because many telescope projects carry relatively small staffs, engineers are often required to perform the additional functions of technical writing, cost estimating, and contract bidding and negotiating. The skills required to carry out these tasks are not normally taught in traditional engineering programs. As a result, engineers often learn to write Request for Proposals (RFPs), select vendors, and negotiate contracts by trial-and-error and/or by adapting previous project documents to match their own requirements. Typically, this means that at the end of a contract the engineer has a large list of do's, don'ts, and lessons learned for the next RFP he or she must generate. This paper will present one such engineer's experience writing and bidding proposal packages for large telescope components and subsystems. Included are: thoughts on structuring SOWs, Specs, ICDs, and other RFP documents; modern methods for bidding the work; and systematic means for selecting and negotiating with a contractor to arrive at the best value for the project.

48 CFR 19.309 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... performed in the United States or its outlying areas. (d) Insert the clause at 52.219-28, Post-Award Small... Business Programs 19.309 Solicitation provisions and contract clauses. (a)(1) Insert the provision at 52... when the contract will be performed in the United States or its outlying areas. (2) Use the provision...

48 CFR 19.309 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... performed in the United States or its outlying areas. (d) Insert the clause at 52.219-28, Post-Award Small... Business Programs 19.309 Solicitation provisions and contract clauses. (a)(1) Insert the provision at 52... when the contract will be performed in the United States or its outlying areas. (2) Use the provision...

Chloride channel blockers promote relaxation of TEA-induced contraction in airway smooth muscle.

PubMed

Yim, Peter D; Gallos, George; Perez-Zoghbi, Jose F; Trice, Jacquelyn; Zhang, Yi; Siviski, Matthew; Sonett, Joshua; Emala, Charles W

2013-01-01

Enhanced airway smooth muscle (ASM) contraction is an important component in the pathophysiology of asthma. We have shown that ligand gated chloride channels modulate ASM contractile tone during the maintenance phase of an induced contraction, however the role of chloride flux in depolarization-induced contraction remains incompletely understood. To better understand the role of chloride flux under these conditions, muscle force (human ASM, guinea pig ASM), peripheral small airway luminal area (rat ASM) and airway smooth muscle plasma membrane electrical potentials (human cultured ASM) were measured. We found ex vivo guinea pig airway rings, human ASM strips and small peripheral airways in rat lungs slices relaxed in response to niflumic acid following depolarization-induced contraction induced by K(+) channel blockade with tetraethylammonium chloride (TEA). In isolated human airway smooth muscle cells TEA induce depolarization as measured by a fluorescent indicator or whole cell patch clamp and this depolarization was reversed by niflumic acid. These findings demonstrate that ASM depolarization induced contraction is dependent on chloride channel activity. Targeting of chloride channels may be a novel approach to relax hypercontractile airway smooth muscle in bronchoconstrictive disorders.

48 CFR 970.1907 - The Small Business Subcontracting Program.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false The Small Business... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small Business Programs 970.1907 The Small Business Subcontracting Program. ...

48 CFR 970.1907 - The Small Business Subcontracting Program.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false The Small Business... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small Business Programs 970.1907 The Small Business Subcontracting Program. ...

48 CFR 970.1907 - The Small Business Subcontracting Program.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false The Small Business... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small Business Programs 970.1907 The Small Business Subcontracting Program. ...

48 CFR 970.1907 - The Small Business Subcontracting Program.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false The Small Business... AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small Business Programs 970.1907 The Small Business Subcontracting Program. ...

Anti-diarrhoeal activity of methanol extract of Santalum album L. in mice and gastrointestinal effect on the contraction of isolated jejunum in rats.

PubMed

Guo, Huimin; Zhang, Jingze; Gao, Wenyuan; Qu, Zhuo; Liu, Changxiao

2014-07-03

Santalum album L., namely Sandalwood, honored as "Green Gold", is a traditional Chinese herb which has the effects of anti-diarrhoeal and antibacterial activity. But there is limit scientific study on its activity and mechanism in gastrointestinal disorders. in vivo, after intragastric administration, the methanol extract of Sandalwood (SE) (200, 400 and 800 mg/kg) were studied in castor oil-induced diarrhoea mice. By the test of small intestinal hyperfunction induced by neostigmine, SE was studied on gastrointestinal transit including gastric emptying and small intestinal motility. Meanwhile, in vitro, the effects of SE (0.02, 0.05, 0.1, 0.2, 0.3, 0.4 mg/mL) on the isolated tissue preparations of rat jejunum were also investigated. The rat jejunum strips were pre-contracted with acetylcholine (Ach; 10(-6)M), 5-hydroxytryptamine (5-HT, 200 μM) or potassium chloride (KCl; 60 mM) and tested in the presence of SE. In addition, the possible myogenic effect was analyzed in the pretreatment of the jejunum preparations with SE or verapamil in Ca(2+)-free high-K(+) (60 mM) solution containing EDTA. At doses of 200, 400 and 800 mg/kg, SE showed significant anti-diarrhoeal activity against castor oil-induced diarrhoea as compared with the control. At the same doses, it also inhibited the gastric emptying and small intestinal motility in the mice of which small intestinal hyperfunction induced by neostigmine. It caused inhibitory effects on the spontaneous contraction of rat-isolated jejunum in dose-dependent manner ranging from 0.02 to 0.4 mg/mL, and it also relaxed the Ach-induced, 5-HT-induced and K(+)-induced contractions. SE shifted the Ca(2+) concentration-response curves to right, similar to that caused by verapamil (0.025 mM). These findings indicated that SE played a spasmolytic role in gastrointestinal motility which was probably mediated through inhibition of muscarinic receptors, 5-HT receptors and calcium influx. All these results provide pharmacological basis for its clinical use in gastrointestinal tract. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

48 CFR 219.1204 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Small... the clause at FAR 52.219-25, Small Disadvantaged Business Participation Program-Disadvantaged Status...

48 CFR 1319.705-4 - Reviewing the subcontracting plan.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... The contracting officer may obtain advice and recommendations from the SBA procurement center representative, the contracting activity's small business specialist and the DOC OSDBU. The CO shall give the...

48 CFR 1319.705-4 - Reviewing the subcontracting plan.

Code of Federal Regulations, 2011 CFR

2011-10-01

.... The contracting officer may obtain advice and recommendations from the SBA procurement center representative, the contracting activity's small business specialist and the DOC OSDBU. The CO shall give the...

48 CFR 419.201 - General policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SMALL BUSINESS PROGRAMS Policies 419.201 General policy. It is the policy of USDA to provide maximum practicable contracting and subcontracting opportunities to small business (SB), small disadvantaged business (SDB), HUBZone small business, women-owned business (WOB), veteran-owned small business (VOSB), and...

The proximal gastric corpus is the most responsive site of motilin-induced contractions in the stomach of the Asian house shrew.

PubMed

Dudani, Amrita; Aizawa, Sayaka; Zhi, Gong; Tanaka, Toru; Jogahara, Takamichi; Sakata, Ichiro; Sakai, Takafumi

2016-07-01

The migrating motor complex (MMC) is responsible for emptying the stomach during the interdigestive period, in preparation for the next meal. It is known that gastric phase III of MMC starts from the proximal stomach and propagates the contraction downwards. We hypothesized that a certain region of the stomach must be more responsive to motilin than others, and that motilin-induced strong gastric contractions propagate from that site. Stomachs of the Suncus or Asian house shrew, a small insectivorous mammal, were dissected and the fundus, proximal corpus, distal corpus, and antrum were examined to study the effect of motilin using an organ bath experiment. Motilin-induced contractions differed in different parts of the stomach. Only the proximal corpus induced gastric contraction even at motilin 10(-10) M, and strong contraction was induced by motilin 10(-9) M in all parts of the stomach. The GPR38 mRNA expression was also higher in the proximal corpus than in the other sections, and the lowest expression was observed in the antrum. GPR38 mRNA expression varied with low expression in the mucosal layer and high expression in the muscle layer. Additionally, motilin-induced contractions in each dissected part of the stomach were inhibited by tetrodotoxin and atropine pretreatment. These results suggest that motilin reactivity is not consistent throughout the stomach, and an area of the proximal corpus including the cardia is the most sensitive to motilin.

Alternatives in Automating Small Procurement Field Activities: A Cost-Benefit Analysis.

DTIC Science & Technology

1986-06-01

with identifying a cost effective means to provide such au- tomation while maintaining continuity throughout the Navy Field Contracting System. There...Proposal is used in lieu of an IFB, and the contracting officer is free to hold meaningful discussions with, and award the contract to the most...It is at this point that the competitive range is estab- lished. The contract specialist will now hold meaningful discussions/negotiations with

Analytical Fuel Property Effects-Small Combustors

DTIC Science & Technology

1984-10-01

Research Center Contract NAS 3-23165 ,_ _---, NASA CR-174738 AVSCOM TR-84-C-14 EDR 11683 Analytical Fuel Property Effects-- Small Combustors by R. D...National Aeronautics and Space Administration NASA Lewis Research Center Contract NAS 3-23165 TABLE OF CONTENTS Section Title ft Summary...would not sustain a flame at normal operating conditions. Frivate communication between Gary Seng of the NASA Lewis Research Center fuel labs and R. D

Alteration of Airway Reactivity and Reduction of Ryanodine Receptor Expression by Cigarette Smoke in Mice.

PubMed

Donovan, Chantal; Seow, Huei Jiunn; Royce, Simon G; Bourke, Jane E; Vlahos, Ross

2015-10-01

Small airways are a major site of airflow limitation in chronic obstructive pulmonary disease (COPD). Despite the detrimental effects of long-term smoking in COPD, the effects of acute cigarette smoke (CS) exposure on small airway reactivity have not been fully elucidated. Balb/C mice were exposed to room air (sham) or CS for 4 days to cause airway inflammation. Changes in small airway lumen area in response to contractile agents were measured in lung slices in situ using phase-contrast microscopy. Separate slices were pharmacologically maintained at constant intracellular Ca(2+) using caffeine/ryanodine before contractile measurements. Gene and protein analysis of contractile signaling pathways were performed on separate lungs. Monophasic contraction to serotonin became biphasic after CS exposure, whereas contraction to methacholine was unaltered. This altered pattern of contraction was normalized by caffeine/ryanodine. Expression of contractile agonist-specific receptors was unaltered; however, all isoforms of the ryanodine receptor were down-regulated. This is the first study to show that acute CS exposure selectively alters small airway contraction to serotonin and down-regulates ryanodine receptors involved in maintaining Ca(2+) oscillations in airway smooth muscle. Understanding the contribution of ryanodine receptors to altered airway reactivity may inform the development of novel treatment strategies for COPD.

Ten-College Conference on Implications of the Bureau of Research Teacher Education Project for Developing Institutions (July 11-12, 1969).

ERIC Educational Resources Information Center

1969

This document reports an initial conference of ten small developing colleges which are contracted to study the feasibility of instituting all or parts of the nine teacher education program models developed in the Teacher Education Project of the U.S. Office of Education (USOE). Included in the report are summaries of prepared statements by each…

48 CFR 819.7009 - Contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS Service-Disabled Veteran-Owned and Veteran-Owned Small Business..., Notice of Total Service-Disabled Veteran-Owned Small Business Set-Aside or 852.219-11, Notice of Total...

48 CFR 819.7009 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROGRAMS SMALL BUSINESS PROGRAMS Service-Disabled Veteran-Owned and Veteran-Owned Small Business..., Notice of Total Service-Disabled Veteran-Owned Small Business Set-Aside or 852.219-11, Notice of Total...

48 CFR 19.505 - Rejecting Small Business Administration recommendations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Rejecting Small Business... REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.505 Rejecting Small Business Administration recommendations. (a) If the contracting officer rejects a recommendation...

48 CFR 19.505 - Rejecting Small Business Administration recommendations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Rejecting Small Business... REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.505 Rejecting Small Business Administration recommendations. (a) If the contracting officer rejects a recommendation...

48 CFR 19.505 - Rejecting Small Business Administration recommendations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Rejecting Small Business... REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.505 Rejecting Small Business Administration recommendations. (a) If the contracting officer rejects a recommendation...

13 CFR 126.604 - Who decides if a contract opportunity for HUBZone set-aside competition exists?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Who decides if a contract opportunity for HUBZone set-aside competition exists? 126.604 Section 126.604 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Contractual Assistance § 126.604 Who decides if a contract...

Small Business Innovation Research. Program solicitation. Closing date: July 21, 1992

NASA Technical Reports Server (NTRS)

1992-01-01

The National Aeronautics and Space Administration (NASA) invites small businesses to submit Phase 1 proposals in response to its Small Business Innovation Research (SBIR) Program Solicitation 92-1. Firms with research or research and development capabilities (R/R&D) in science or engineering in any of the areas listed are encouraged to participate. This, the tenth annual SBIR solicitation by NASA, describes the program, identifies eligibility requirements, describes the proposal evaluation and award selection process, and provides other information to assist those interested in participating in NASA's SBIR program. It also identifies, in Section 8.0, the technical topics and subtopics in which SBIR Phase 1 proposals are solicited in 1992. These topics and subtopics cover a broad range of current NASA interests but do not necessarily include all areas in which NASA plans or currently conducts research. The NASA SBIR program seeks innovative approaches that respond to the needs, technical requirements, and new opportunities described in the subtopics. The focus is on innovation through the use of emerging technologies, novel applications of existing technologies, exploitation of scientific breakthroughs, or new capabilities or major improvements to existing technologies. NASA plans to select about 320 high-quality research or research and development proposals for Phase 1 contract awards on the basis of this Solicitation. Phase 1 contracts are normally six months in duration and funded up to $50,000, including profit. Selections will be based on the competitive merits of the offers and on NASA needs and priorities.

48 CFR 19.506 - Withdrawing or modifying small business set-asides.

Code of Federal Regulations, 2014 CFR

2014-10-01

... small business set-asides. 19.506 Section 19.506 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.506 Withdrawing or modifying small business set-asides. (a) If, before award of a contract involving a small...

48 CFR 19.506 - Withdrawing or modifying small business set-asides.

Code of Federal Regulations, 2013 CFR

2013-10-01

... small business set-asides. 19.506 Section 19.506 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.506 Withdrawing or modifying small business set-asides. (a) If, before award of a contract involving a small...

48 CFR 19.506 - Withdrawing or modifying small business set-asides.

Code of Federal Regulations, 2011 CFR

2011-10-01

... small business set-asides. 19.506 Section 19.506 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.506 Withdrawing or modifying small business set-asides. (a) If, before award of a contract involving a small...

48 CFR 19.506 - Withdrawing or modifying small business set-asides.

Code of Federal Regulations, 2012 CFR

2012-10-01

... small business set-asides. 19.506 Section 19.506 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.506 Withdrawing or modifying small business set-asides. (a) If, before award of a contract involving a small...

Ginger Extract and [6]-Gingerol Inhibit Contraction of Rat Entire Small Intestine.

PubMed

Chatturong, Usana; Kajsongkram, Tanwarat; Tunsophon, Sakara; Chanasong, Rachanee; Chootip, Krongkarn

2018-01-01

This study aims to investigate the effect of oral administration and the direct action of ginger extract or [6]-gingerol on small intestinal contractility. The direct effect of 10 minutes preincubation of ginger ethanolic extract (10, 100 and 300 μg/mL) or [6]-gingerol (1, 30, and 100 μM) on 0.01 to 30 μM ACh-induced contractions of all parts of the small intestine isolated from normal rats was investigated using the organ bath technique. For in vivo study, the rats were orally administered with extract (10, 20, and 100 mg/kg/d) or [6]-gingerol (2 mg/kg/d) for 7 days, followed by determining the contractile responses to ACh of rat isolated duodenum, jejunum, and ileum and their histology were assessed. Direct application of the extract or [6]-gingerol attenuated ACh-induced contractions in each small intestinal segment, E max was reduced by 40% to 80%, while EC 50 increased 3- to 8-fold from control. Similarly, in the in vivo study ACh-induced contractions were reduced in all parts of the small intestine isolated from rats orally treated with ginger extract (20 and 100 mg/kg/d) or [6]-gingerol (2 mg/kg/d). E max decreased 15% to 30%, while EC 50 increased 1- to 3-fold compared to control. No discernable changes in the histology of intestinal segments were detectable. Thus, the results support the clinical application of ginger for disorders of gastrointestinal motility.

48 CFR 19.202-2 - Locating small business sources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

48 CFR 19.202-2 - Locating small business sources.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

48 CFR 19.202-2 - Locating small business sources.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

48 CFR 19.202-2 - Locating small business sources.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

48 CFR 19.202-2 - Locating small business sources.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 19.202-2 Locating small business sources. The contracting officer must, to the extent practicable, encourage maximum participation by small business...

22 CFR 208.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Are any procurement contracts included as... contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

22 CFR 208.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Are any procurement contracts included as... contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

22 CFR 1508.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Are any procurement contracts included as... contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

Advanced Modulation and Coding Technology Conference

NASA Technical Reports Server (NTRS)

1992-01-01

The objectives, approach, and status of all current LeRC-sponsored industry contracts and university grants are presented. The following topics are covered: (1) the LeRC Space Communications Program, and Advanced Modulation and Coding Projects; (2) the status of four contracts for development of proof-of-concept modems; (3) modulation and coding work done under three university grants, two small business innovation research contracts, and two demonstration model hardware development contracts; and (4) technology needs and opportunities for future missions.

48 CFR 1913.505-2 - Board order forms in lieu of Optional and Standard Forms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... BROADCASTING BOARD OF GOVERNORS CONTRACTING METHODS AND CONTRACT TYPES SMALL PURCHASES AND OTHER SIMPLIFIED...-case basis, in order to accommodate computer-generated purchase order forms. Exception approval for...

48 CFR 1913.505-2 - Board order forms in lieu of Optional and Standard Forms.

Code of Federal Regulations, 2010 CFR

2010-10-01

... BROADCASTING BOARD OF GOVERNORS CONTRACTING METHODS AND CONTRACT TYPES SMALL PURCHASES AND OTHER SIMPLIFIED...-case basis, in order to accommodate computer-generated purchase order forms. Exception approval for...

48 CFR 19.502-2 - Total small business set-asides.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Total small business set... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.502-2 Total small business set... exclusively for small business concerns and shall be set aside for small business unless the contracting...

System Would Regulate Low Gas Pressure

NASA Technical Reports Server (NTRS)

Frazer, Robert E.

1994-01-01

System intended to maintain gases in containers at pressures near atmospheric. Includes ballast volume in form of underinflated balloon that communicates with working volume. Balloon housed in rigid chamber not subjected to extremes of temperature of working volume. Pressure in chamber surrounding balloon regulated at ambient atmospheric pressure or at constant small differential pressure above or below ambient. Expansion and contraction of balloon accommodates expansion or contraction of gas during operational heating or cooling in working volume, maintaining pressure in working volume at ambient or constant differential above or below ambient. Gas lost from system due to leakage or diffusion, low-pressure sensor responds, signaling valve actuators to supply more gas to working volume. If pressure rises too high, overpressure relief valve opens before excessive pressure damages system.

Subcontracting Opportunities with DoD Major Prime Contractors

DTIC Science & Technology

1996-06-01

The Department of Defense (DoD) offers two markets for small business and small disadvantaged business seeking defense contracting and defense...opportunities. The publication exclusively addresses the defense subcontracting opportunities market. The DoD encourages small business and small disadvantaged

48 CFR 53.219 - Small Business Programs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

41 CFR 109-40.110-1 - Small business assistance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Small business... Small business assistance. Consistent with the policies of the Government with respect to small businesses, DOE shall place with small business concerns a fair proportion of the total purchases and...

48 CFR 53.219 - Small Business Programs.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

41 CFR 109-40.110-1 - Small business assistance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Small business... Small business assistance. Consistent with the policies of the Government with respect to small businesses, DOE shall place with small business concerns a fair proportion of the total purchases and...

41 CFR 109-40.110-1 - Small business assistance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Small business... Small business assistance. Consistent with the policies of the Government with respect to small businesses, DOE shall place with small business concerns a fair proportion of the total purchases and...

48 CFR 53.219 - Small Business Programs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

48 CFR 53.219 - Small Business Programs.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

48 CFR 53.219 - Small Business Programs.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The following form may be used in reporting small disadvantaged business contracting data: OF 312 (10/00), Small...

48 CFR 19.706 - Responsibilities of the cognizant administrative contracting officer.

Code of Federal Regulations, 2010 CFR

2010-10-01

... business, HUBZone small business, small disadvantaged business, and women-owned small business concerns; (c) Information on whether the contractor's efforts to ensure the participation of small business, veteran-owned... disadvantaged business, and women-owned small business concerns are in accordance with its subcontracting plan...

48 CFR 42.502 - Selecting contracts for postaward orientation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the product or service to critical programs; (f) Length of the planned production cycle; (g) Extent of... status, if any, as a small business, small disadvantaged, women-owned, veteran-owned, HUBZone, or service-disabled veteran-owned small business concern; (j) Contractor's performance history with small, small...

48 CFR 419.201-71 - Small business coordinators.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 419.201-71 Small business coordinators. The head of the contracting activity (HCA) or a representative of the HCA shall designate in writing a small business...

41 CFR 109-40.110-1 - Small business assistance.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Small business... Small business assistance. Consistent with the policies of the Government with respect to small businesses, DOE shall place with small business concerns a fair proportion of the total purchases and...

41 CFR 109-40.110-1 - Small business assistance.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Small business... Small business assistance. Consistent with the policies of the Government with respect to small businesses, DOE shall place with small business concerns a fair proportion of the total purchases and...

13 CFR 126.608 - Are there HUBZone contract opportunities at or below the simplified acquisition threshold or...

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Are there HUBZone contract opportunities at or below the simplified acquisition threshold or micropurchase threshold? 126.608 Section 126.608 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Contractual Assistance § 126.608 Are there HUBZone contract...

13 CFR 126.608 - Are there HUBZone contract opportunities at or below the simplified acquisition threshold or...

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Are there HUBZone contract opportunities at or below the simplified acquisition threshold or micropurchase threshold? 126.608 Section 126.608 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Contractual Assistance § 126.608 Are there HUBZone contract...

13 CFR 126.608 - Are there HUBZone contract opportunities at or below the simplified acquisition threshold or...

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Are there HUBZone contract opportunities at or below the simplified acquisition threshold or micropurchase threshold? 126.608 Section 126.608 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Contractual Assistance § 126.608 Are there HUBZone contract...

13 CFR 126.608 - Are there HUBZone contract opportunities at or below the simplified acquisition threshold or...

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Are there HUBZone contract opportunities at or below the simplified acquisition threshold or micropurchase threshold? 126.608 Section 126.608 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Contractual Assistance § 126.608 Are there HUBZone contract...

13 CFR 126.608 - Are there HUBZone contract opportunities at or below the simplified acquisition threshold or...

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Are there HUBZone contract opportunities at or below the simplified acquisition threshold or micropurchase threshold? 126.608 Section 126.608 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Contractual Assistance § 126.608 Are there HUBZone contract...

Chloride channel blockers promote relaxation of TEA-induced contraction in airway smooth muscle

PubMed Central

Yim, Peter D.; Gallos, George; Perez-zoghbi, Jose F.; Trice, Jacquelyn; Zhang, Yi; Siviski, Matthew; Sonett, Joshua; Emala, Charles W.

2014-01-01

Enhanced airway smooth muscle (ASM) contraction is an important component in the pathophysiology of asthma. We have shown that ligand gated chloride channels modulate ASM contractile tone during the maintenance phase of an induced contraction, however the role of chloride flux in depolarization-induced contraction remains incompletely understood. To better understand the role of chloride flux under these conditions, muscle force (human ASM, guinea pig ASM), peripheral small airway luminal area (rat ASM) and airway smooth muscle plasma membrane electrical potentials (human cultured ASM) were measured. We found ex vivo guinea pig airway rings, human ASM strips and small peripheral airways in rat lungs slices relaxed in response to niflumic acid following depolarization-induced contraction induced by K+ channel blockade with tetraethylammonium chloride (TEA). In isolated human airway smooth muscle cells TEA induce depolarization as measured by a fluorescent indicator or whole cell patch clamp and this depolarization was reversed by niflumic acid. These findings demonstrate that ASM depolarization induced contraction is dependent on chloride channel activity. Targeting of chloride channels may be a novel approach to relax hypercontractile airway smooth muscle in bronchoconstrictive disorders. PMID:24662476

Contracting out of health services in developing countries.

PubMed

McPake, B; Banda, E E

1994-03-01

Contracting out is emerging as a common policy issue in a number of developing countries. The theoretical case for contracting out suggests many advantages in combining public finance with private provision. However, practical difficulties such as those of ensuring that competition takes place between potential contractors, that competition leads to efficiency and that contracts and the process of contracting are effectively managed, suggest that such advantages may not always be realized. Most countries are likely only to contemplate restricted contracting of small-scale non-clinical services in the short term. Prerequisites of more extensive models appear to be the development of information systems and human resources to that end. Some urban areas of larger countries may have the existing preconditions for more successful large-scale contracting.

48 CFR 752.219-8 - Utilization of small business concerns and small disadvantaged business concerns.

Code of Federal Regulations, 2010 CFR

2010-10-01

... business concerns and small disadvantaged business concerns. 752.219-8 Section 752.219-8 Federal... AND CONTRACT CLAUSES Texts of Provisions and Clauses 752.219-8 Utilization of small business concerns and small disadvantaged business concerns. The Foreign Assistance Act calls for USAID to give small...

48 CFR 19.502-2 - Total small business set-asides.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Total small business set... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.502-2 Total small business set... contracting officer does not proceed with the small business set-aside and purchases on an unrestricted basis...

48 CFR 19.502-2 - Total small business set-asides.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Total small business set... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.502-2 Total small business set... contracting officer does not proceed with the small business set-aside and purchases on an unrestricted basis...

48 CFR 19.502-2 - Total small business set-asides.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Total small business set... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Set-Asides for Small Business 19.502-2 Total small business set... contracting officer does not proceed with the small business set-aside and purchases on an unrestricted basis...

48 CFR 752.219-8 - Utilization of small business concerns and small disadvantaged business concerns.

Code of Federal Regulations, 2011 CFR

2011-10-01

... business concerns and small disadvantaged business concerns. 752.219-8 Section 752.219-8 Federal... AND CONTRACT CLAUSES Texts of Provisions and Clauses 752.219-8 Utilization of small business concerns and small disadvantaged business concerns. The Foreign Assistance Act calls for USAID to give small...

48 CFR 219.800 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (Acquisition, Technology, and Logistics) its authority under paragraph 8(a)(1)(A) of the Small Business Act (15... DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business Administration (The 8(a) Program) 219.800 General. (a) By Partnership Agreement (PA) between the Small Business...

48 CFR 919.705-6 - Postaward responsibilities of the contracting officer.

Code of Federal Regulations, 2010 CFR

2010-10-01

... DEPARTMENT OF ENERGY SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Subcontracting With Small Business, Small Disadvantaged Business, and Women-Owned Small Business Concerns 919.705-6 Postaward responsibilities of the... Small and Disadvantaged Business Utilization. [49 FR 11997, Mar. 28, 1984, as amended at 59 FR 9106, Feb...

48 CFR 19.501 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

...). (i) Except as authorized by law, a contract may not be awarded as a result of a small business set... BUSINESS PROGRAMS Set-Asides for Small Business 19.501 General. (a) The purpose of small business set-asides is to award certain acquisitions exclusively to small business concerns. A “set-aside for small...

Regulation of Contraction by the Thick Filaments in Skeletal Muscle.

PubMed

Irving, Malcolm

2017-12-19

Contraction of skeletal muscle cells is initiated by a well-known signaling pathway. An action potential in a motor nerve triggers an action potential in a muscle cell membrane, a transient increase of intracellular calcium concentration, binding of calcium to troponin in the actin-containing thin filaments, and a structural change in the thin filaments that allows myosin motors from the thick filaments to bind to actin and generate force. This calcium/thin filament mediated pathway provides the "START" signal for contraction, but it is argued that the functional response of the muscle cell, including the speed of its contraction and relaxation, adaptation to the external load, and the metabolic cost of contraction is largely determined by additional mechanisms. This review considers the role of the thick filaments in those mechanisms, and puts forward a paradigm for the control of contraction in skeletal muscle in which both the thick and thin filaments have a regulatory function. The OFF state of the thick filament is characterized by helical packing of most of the myosin head or motor domains on the thick filament surface in a conformation that makes them unavailable for actin binding or ATP hydrolysis, although a small fraction of the myosin heads are constitutively ON. The availability of the majority fraction of the myosin heads for contraction is controlled in part by the external load on the muscle, so that these heads only attach to actin and hydrolyze ATP when they are required. This phenomenon seems to be the major determinant of the well-known force-velocity relationship of muscle, and controls the metabolic cost of contraction. The regulatory state of the thick filament also seems to control the dynamics of both muscle activation and relaxation. Copyright © 2017 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Contract Funding Opportunities Available for Innovative SBIR Development | Office of Cancer Clinical Proteomics Research

Cancer.gov

Does your small business need early-stage financing to take its cancer research to the next level? The National Cancer Institute Small Business Innovation Research (NCI SBIR) Development Center has released $5 million for new contract funding opportunities to support cancer research and technology development in key emerging areas of need. The NCI SBIR can help you finance and advance innovations in cancer prevention, diagnosis, treatment, and basic research.

42 CFR 434.6 - General requirements for all contracts and subcontracts. P>(a) Contracts. All contracts under...

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 4 2011-10-01 2011-10-01 false General requirements for all contracts and subcontracts. P>(a) Contracts. All contracts under this part must include all of the following: 434.6 Section... contracts and subcontracts.P>(a) Contracts. All contracts under this part must include all of the following...

48 CFR 1852.219-83 - Limitation of the principal investigator-SBIR program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 2006) The primary employment of the principal investigator (PI) shall be with the small business... of the contract. The PI for this contract is (insert name). (End of clause) [71 FR 61688, Oct. 19...

Genetic analysis reveals demographic fragmentation of grizzly bears yielding vulnerably small populations

PubMed Central

Proctor, Michael F; McLellan, Bruce N; Strobeck, Curtis; Barclay, Robert M.R

2005-01-01

Ecosystem conservation requires the presence of native carnivores, yet in North America, the distributions of many larger carnivores have contracted. Large carnivores live at low densities and require large areas to thrive at the population level. Therefore, if human-dominated landscapes fragment remaining carnivore populations, small and demographically vulnerable populations may result. Grizzly bear range contraction in the conterminous USA has left four fragmented populations, three of which remain along the Canada–USA border. A tenet of grizzly bear conservation is that the viability of these populations requires demographic linkage (i.e. inter-population movement of both sexes) to Canadian bears. Using individual-based genetic analysis, our results suggest this demographic connection has been severed across their entire range in southern Canada by a highway and associated settlements, limiting female and reducing male movement. Two resulting populations are vulnerably small (≤100 animals) and one of these is completely isolated. Our results suggest that these trans-border bear populations may be more threatened than previously thought and that conservation efforts must expand to include international connectivity management. They also demonstrate the ability of genetic analysis to detect gender-specific demographic population fragmentation in recently disturbed systems, a traditionally intractable yet increasingly important ecological measurement worldwide. PMID:16243699

Genetic analysis reveals demographic fragmentation of grizzly bears yielding vulnerably small populations.

PubMed

Proctor, Michael F; McLellan, Bruce N; Strobeck, Curtis; Barclay, Robert M R

2005-11-22

Ecosystem conservation requires the presence of native carnivores, yet in North America, the distributions of many larger carnivores have contracted. Large carnivores live at low densities and require large areas to thrive at the population level. Therefore, if human-dominated landscapes fragment remaining carnivore populations, small and demographically vulnerable populations may result. Grizzly bear range contraction in the conterminous USA has left four fragmented populations, three of which remain along the Canada-USA border. A tenet of grizzly bear conservation is that the viability of these populations requires demographic linkage (i.e. inter-population movement of both sexes) to Canadian bears. Using individual-based genetic analysis, our results suggest this demographic connection has been severed across their entire range in southern Canada by a highway and associated settlements, limiting female and reducing male movement. Two resulting populations are vulnerably small (< or =100 animals) and one of these is completely isolated. Our results suggest that these trans-border bear populations may be more threatened than previously thought and that conservation efforts must expand to include international connectivity management. They also demonstrate the ability of genetic analysis to detect gender-specific demographic population fragmentation in recently disturbed systems, a traditionally intractable yet increasingly important ecological measurement worldwide.

Regulation and dysregulation of esophageal peristalsis by the integrated function of circular and longitudinal muscle layers in health and disease.

PubMed

Mittal, Ravinder K

2016-09-01

Muscularis propria throughout the entire gastrointestinal tract including the esophagus is comprised of circular and longitudinal muscle layers. Based on the studies conducted in the colon and the small intestine, for more than a century, it has been debated whether the two muscle layers contract synchronously or reciprocally during the ascending contraction and descending relaxation of the peristaltic reflex. Recent studies in the esophagus and colon prove that the two muscle layers indeed contract and relax together in almost perfect synchrony during ascending contraction and descending relaxation of the peristaltic reflex, respectively. Studies in patients with various types of esophageal motor disorders reveal temporal disassociation between the circular and longitudinal muscle layers. We suggest that the discoordination between the two muscle layers plays a role in the genesis of esophageal symptoms, i.e., dysphagia and esophageal pain. Certain pathologies may selectively target one and not the other muscle layer, e.g., in eosinophilic esophagitis there is a selective dysfunction of the longitudinal muscle layer. In achalasia esophagus, swallows are accompanied by the strong contraction of the longitudinal muscle without circular muscle contraction. The possibility that the discoordination between two muscle layers plays a role in the genesis of esophageal symptoms, i.e., dysphagia and esophageal pain are discussed. The purpose of this review is to summarize the regulation and dysregulation of peristalsis by the coordinated and discoordinated function of circular and longitudinal muscle layers in health and diseased states.

Regulation and dysregulation of esophageal peristalsis by the integrated function of circular and longitudinal muscle layers in health and disease

PubMed Central

2016-01-01

Muscularis propria throughout the entire gastrointestinal tract including the esophagus is comprised of circular and longitudinal muscle layers. Based on the studies conducted in the colon and the small intestine, for more than a century, it has been debated whether the two muscle layers contract synchronously or reciprocally during the ascending contraction and descending relaxation of the peristaltic reflex. Recent studies in the esophagus and colon prove that the two muscle layers indeed contract and relax together in almost perfect synchrony during ascending contraction and descending relaxation of the peristaltic reflex, respectively. Studies in patients with various types of esophageal motor disorders reveal temporal disassociation between the circular and longitudinal muscle layers. We suggest that the discoordination between the two muscle layers plays a role in the genesis of esophageal symptoms, i.e., dysphagia and esophageal pain. Certain pathologies may selectively target one and not the other muscle layer, e.g., in eosinophilic esophagitis there is a selective dysfunction of the longitudinal muscle layer. In achalasia esophagus, swallows are accompanied by the strong contraction of the longitudinal muscle without circular muscle contraction. The possibility that the discoordination between two muscle layers plays a role in the genesis of esophageal symptoms, i.e., dysphagia and esophageal pain are discussed. The purpose of this review is to summarize the regulation and dysregulation of peristalsis by the coordinated and discoordinated function of circular and longitudinal muscle layers in health and diseased states. PMID:27445346

48 CFR 970.1907-1 - Subcontracting plan requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small, Small Disadvantaged and Women-Owned Small Business Concerns 970.1907-1 Subcontracting plan requirements. Pursuant to the clause at 48 CFR 52.219-9, Small Business Subcontracting Plan, which is required for all management and operating...

48 CFR 519.7002 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-owned small business concern, veteran-owned small business concern, and service-disabled veteran-owned small business concern are the same as found in FAR 2.101. Also see 13 CFR 121, 124, 125 and 126. (a... contract, to promote and develop small business subcontractors by providing developmental assistance...

48 CFR 519.7002 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-owned small business concern, veteran-owned small business concern, and service-disabled veteran-owned small business concern are the same as found in FAR 2.101. Also see 13 CFR 121, 124, 125 and 126. (a... contract, to promote and develop small business subcontractors by providing developmental assistance...

37 CFR 401.7 - Small business preference.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Small business preference..., DEPARTMENT OF COMMERCE RIGHTS TO INVENTIONS MADE BY NONPROFIT ORGANIZATIONS AND SMALL BUSINESS FIRMS UNDER GOVERNMENT GRANTS, CONTRACTS, AND COOPERATIVE AGREEMENTS § 401.7 Small business preference. (a) Paragraph (k...

37 CFR 401.7 - Small business preference.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Small business preference..., DEPARTMENT OF COMMERCE RIGHTS TO INVENTIONS MADE BY NONPROFIT ORGANIZATIONS AND SMALL BUSINESS FIRMS UNDER GOVERNMENT GRANTS, CONTRACTS, AND COOPERATIVE AGREEMENTS § 401.7 Small business preference. (a) Paragraph (k...

37 CFR 401.7 - Small business preference.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Small business preference..., DEPARTMENT OF COMMERCE RIGHTS TO INVENTIONS MADE BY NONPROFIT ORGANIZATIONS AND SMALL BUSINESS FIRMS UNDER GOVERNMENT GRANTS, CONTRACTS, AND COOPERATIVE AGREEMENTS § 401.7 Small business preference. (a) Paragraph (k...

49 CFR 26.39 - Fostering small business participation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 1 2014-10-01 2014-10-01 false Fostering small business participation. 26.39... Requirements for DBE Programs for Federally-Assisted Contracting § 26.39 Fostering small business participation... competition by small business concerns, taking all reasonable steps to eliminate obstacles to their...

37 CFR 401.7 - Small business preference.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Small business preference..., DEPARTMENT OF COMMERCE RIGHTS TO INVENTIONS MADE BY NONPROFIT ORGANIZATIONS AND SMALL BUSINESS FIRMS UNDER GOVERNMENT GRANTS, CONTRACTS, AND COOPERATIVE AGREEMENTS § 401.7 Small business preference. (a) Paragraph (k...

37 CFR 401.7 - Small business preference.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Small business preference..., DEPARTMENT OF COMMERCE RIGHTS TO INVENTIONS MADE BY NONPROFIT ORGANIZATIONS AND SMALL BUSINESS FIRMS UNDER GOVERNMENT GRANTS, CONTRACTS, AND COOPERATIVE AGREEMENTS § 401.7 Small business preference. (a) Paragraph (k...

49 CFR 26.39 - Fostering small business participation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false Fostering small business participation. 26.39... Requirements for DBE Programs for Federally-Assisted Contracting § 26.39 Fostering small business participation... competition by small business concerns, taking all reasonable steps to eliminate obstacles to their...

Automatic Conflict Detection on Contracts

NASA Astrophysics Data System (ADS)

Fenech, Stephen; Pace, Gordon J.; Schneider, Gerardo

Many software applications are based on collaborating, yet competing, agents or virtual organisations exchanging services. Contracts, expressing obligations, permissions and prohibitions of the different actors, can be used to protect the interests of the organisations engaged in such service exchange. However, the potentially dynamic composition of services with different contracts, and the combination of service contracts with local contracts can give rise to unexpected conflicts, exposing the need for automatic techniques for contract analysis. In this paper we look at automatic analysis techniques for contracts written in the contract language mathcal{CL}. We present a trace semantics of mathcal{CL} suitable for conflict analysis, and a decision procedure for detecting conflicts (together with its proof of soundness, completeness and termination). We also discuss its implementation and look into the applications of the contract analysis approach we present. These techniques are applied to a small case study of an airline check-in desk.

Effects of hypothyroidism on the skeletal muscle blood flow response to contractions.

PubMed

Bausch, L; McAllister, R M

2003-04-01

Hypothyroidism is associated with impaired blood flow to skeletal muscle under whole body exercise conditions. It is unclear whether poor cardiac and/or vascular function account for blunted muscle blood flow. Our experiment isolated a small group of hindlimb muscles and simulated exercise via tetanic contractions. We hypothesized that muscle blood flow would be attenuated in hypothyroid rats (HYPO) compared with euthyroid rats (EUT). Rats were made hypothyroid by mixing propylthiouracil in their drinking water (2.35 x 10-3 mol/l). Treatment efficacy was evidenced by lower serum T3 concentrations and resting heart rates in HYPO (both P<0.05). In the experimental preparation, isometric contractions of the lower right hindlimb muscles at a rate of 30 tetani/min were induced via sciatic nerve stimulation. Regional blood flows were determined by the radiolabelled microsphere method at three time points: rest, 2 min of contractions and 10 min of contractions. Muscle blood flow generally increased from rest ( approximately 5-10 ml/min per 100 g) through contractions for both groups. Further, blood flow during contractions did not differ between groups for any muscle (eg. red section of gastrocnemius muscle; EUT, 59.9 +/- 14.1; HYPO, 61.1 +/- 15.0; NS between groups). These findings indicate that hypothyroidism does not significantly impair skeletal muscle blood flow when only a small muscle mass is contracting. Our findings suggest that impaired blood flow under whole body exercise is accounted for by inadequate cardiac function rather than abnormal vascular function.

Electromyographic analysis of exercise resulting in symptoms of muscle damage.

PubMed

McHugh, M P; Connolly, D A; Eston, R G; Gleim, G W

2000-03-01

Surface electromyographic (EMG) signals were recorded from the hamstring muscles during six sets of submaximal isokinetic (2.6 rad x s(-1)) eccentric (11 men, 9 women) or concentric (6 men, 4 women) contractions. The EMG per unit torque increased during eccentric (P < 0.01) but not during concentric exercise. Similarly, the median frequency increased during eccentric (P < 0.01) but not during concentric exercise. The EMG per unit torque was lower for submaximal eccentric than maximum isometric contractions (P < 0.001), and lower for submaximal concentric than maximum isometric contractions (P < 0.01). The EMG per unit torque was lower for eccentric than concentric contractions (P < 0.05). The median frequency was higher for submaximal eccentric than maximum isometric contractions (P < 0.001); it was similar, however, between submaximal concentric and maximum isometric contractions (P = 0.07). Eccentric exercise resulted in significant isometric strength loss (P < 0.01), pain (P < 0.01) and muscle tenderness (P < 0.05). The greatest strength loss was seen 1 day after eccentric exercise, while the most severe pain and muscle tenderness occurred 2 days after eccentric exercise. A lower EMG per unit torque is consistent with the selective recruitment of a small number of motor units during eccentric exercise. A higher median frequency during eccentric contractions may be explained by selective recruitment of fast-twitch motor units. The present results are consistent with the theory that muscle damage results from excessive stress on a small number of active fibres during eccentric contractions.

48 CFR 2009.100 - NRC policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... noncompetitive award of contracts to organizations where former NRC employees have dominant management interests...) Contracts awarded noncompetitively under the Small Business Administration's 8(a) Program; (2) Individual... consulting with the Executive Director for Operations. This is in addition to any justification and approvals...

48 CFR 1419.901 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... BUSINESS PROGRAMS Contracting Opportunities for Women-Owned Small Businesses 1419.901 Policy. In support of the Department's policy to facilitate, preserve, and strengthen women's business enterprises: (a) Annual goals for contract awards to women-owned businesses shall be established as prescribed in 1419.201...

13 CFR 127.506 - May a joint venture submit an offer on an EDWOSB or WOSB requirement?

Code of Federal Regulations, 2010 CFR

2010-01-01

... BUSINESS ADMINISTRATION WOMEN-OWNED SMALL BUSINESS FEDERAL CONTRACT ASSISTANCE PROCEDURES Federal Contract... applicable percentage of work required of the EDWOSB or WOSB offerors in accordance with § 125.6 of this...

22 CFR 1006.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Are any procurement contracts included as... DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 1006.220 Are any procurement contracts... procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

21 CFR 1404.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Are any procurement contracts included as covered... DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 1404.220 Are any procurement contracts... procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

21 CFR 1404.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Are any procurement contracts included as covered... DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 1404.220 Are any procurement contracts... procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

34 CFR 85.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Are any procurement contracts included as covered... DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 85.220 Are any procurement contracts... procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 3052.219-70 - Small Business subcontracting program reporting.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Small Business... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 3052.219-70 Small Business...: Small Business Subcontracting Plan Reporting (JUN 2006) (a) The Contractor shall enter the information...

48 CFR 52.219-26 - Small Disadvantaged Business Participation Program-Incentive Subcontracting.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACT CLAUSES Text of Provisions and Clauses 52.219-26 Small Disadvantaged Business Participation... the following: Small Disadvantaged Business Participation Program—Incentive Subcontracting (OCT 2000... its offer to try to award a certain amount to small disadvantaged business concerns in the North...

48 CFR 3052.219-70 - Small Business subcontracting program reporting.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Small Business... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 3052.219-70 Small Business...: Small Business Subcontracting Plan Reporting (JUN 2006) (a) The Contractor shall enter the information...

48 CFR 3052.219-70 - Small Business subcontracting program reporting.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Small Business... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 3052.219-70 Small Business...: Small Business Subcontracting Plan Reporting (JUN 2006) (a) The Contractor shall enter the information...

48 CFR 3052.219-70 - Small Business subcontracting program reporting.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Small Business... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 3052.219-70 Small Business...: Small Business Subcontracting Plan Reporting (JUN 2006) (a) The Contractor shall enter the information...

48 CFR 3052.219-70 - Small Business subcontracting program reporting.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Small Business... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 3052.219-70 Small Business...: Small Business Subcontracting Plan Reporting (JUN 2006) (a) The Contractor shall enter the information...

75 FR 22499 - Establishing an Interagency Task Force on Federal Contracting Opportunities for Small Businesses

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-29

... tap into the talents and skills of a broad cross-section of American business and industry. Small... Office of Management and Budget (Director), and the Administrator of the Small Business Administration...

3D power Doppler ultrasound assessment of placental perfusion during uterine contraction in labor.

PubMed

Sato, Miki; Noguchi, Junko; Mashima, Masato; Tanaka, Hirokazu; Hata, Toshiyuki

2016-09-01

To assess placental perfusion during spontaneous or induced uterine contraction in labor at term using placental vascular sonobiopsy (PVS) by 3D power Doppler ultrasound with the VOCAL imaging analysis program. PVS was performed in 50 normal pregnancies (32 in spontaneous labor group [SLG], and 18 in induced labor group with oxytocin or prostaglandin F2α [ILG]) at 37-41 weeks of gestation to assess placental perfusion during uterine contraction in labor. Only pregnancies with an entirely visualized anterior placenta were included in the study. Data acquisition was performed before, during (at the peak of contraction), and after uterine contraction. 3D power Doppler indices such as the vascularization index (VI), flow index (FI), and vascularization flow index (VFI) were calculated in each placenta. There were no abnormal fetal heart rate tracings during contraction in either group. VI and VFI values were significantly reduced during uterine contraction in both groups (SLG, -33.4% [-97.0-15.2%], and ILG, -49.6% [-78.2--4.0%]), respectively (P < 0.001). The FI value in the ILG group was significantly lower during uterine contraction (P = 0.035), whereas it did not change during uterine contraction in the SLG group. After uterine contraction, all vascular indices returned almost to the same level as that before uterine contraction. However, the FI value in ILG (-8.6%, [-19.7-16.0%]) was significantly lower than that in SLG (2.4%, [-13.4-38.1%]) after uterine contraction (P < 0.05). All 3D power Doppler indices (VI, FI, and VFI) during uterine contraction (at the peak of contraction) showed a correlation greater than 0.7, with good intra- and inter-observer agreements. Our findings suggest that uterine contraction in both spontaneous and induced labors causes a significant reduction in placental perfusion. Reduced placental blood flow in induced uterine contraction has a tendency to be marked compared with that in spontaneous uterine contraction. To the best of our knowledge, this is the first study on the non-invasive assessment of placental perfusion during uterine contraction in labor using 3D power Doppler ultrasound. However, the data and their interpretation in the present study should be taken with some degree of caution because of the small number of subjects studied. Further studies involving a larger sample size are needed to assess placental perfusion and vascularity using PVS during normal and abnormal uterine contractions in normal and high-risk pregnancies. Copyright © 2016 Elsevier Ltd. All rights reserved.

48 CFR 1552.209-74 - Limitation of future contracting.

Code of Federal Regulations, 2014 CFR

2014-10-01

... preclude START contractors from performing construction management services under other EPA contracts. (3... Contracting Officer. Examples of such contracts include, but are not limited to, Superfund Management and... Contracting Officer. Examples of such contracts include, but are not limited to, Superfund Management and...

48 CFR 1552.209-74 - Limitation of future contracting.

Code of Federal Regulations, 2013 CFR

2013-10-01

... preclude START contractors from performing construction management services under other EPA contracts. (3... Contracting Officer. Examples of such contracts include, but are not limited to, Superfund Management and... Contracting Officer. Examples of such contracts include, but are not limited to, Superfund Management and...

Robot Handcontroller

NASA Technical Reports Server (NTRS)

1992-01-01

The PER-Force robotic handcontroller provides a sense of touch or "feel" to an operator manipulating robots. The force simulation and wide range of motion greatly enhances the efficiency of robotic and computer operations. The handcontroller was developed for the Space Station by Cybernet Systems Corporation under a Small Business Innovation Research (SBIR) contract. Commercial applications include underwater use, underground excavations, research laboratories, hazardous waste handling and in manufacturing operations in which it is unsafe or impractical for humans to work.

Go With the Flow

NASA Technical Reports Server (NTRS)

1998-01-01

Under SBIR (Small Business Innovative Research) contracts with Lewis Research Center, Nektonics, Inc., developed coating process simulation tools, known as Nekton. This powerful simulation software is used specifically for the modeling and analysis of a wide range of coating flows including thin film coating analysis, polymer processing, and glass melt flows. Polaroid, Xerox, 3M, Dow Corning, Mead Paper, BASF, Mitsubishi, Chugai, and Dupont Imaging Systems are only a few of the companies that presently use Nekton.

The Weapons Laboratory Technical Library: Automating with ’Stilas’

DTIC Science & Technology

1990-03-01

version of the system to LC in October 1988. -X- A small business specializing in library automation, SIRSI was founded in 1979 by library and...computer specialists, and has a strong reputation based upon the success of their UNIX-based Unicorn Collection Management System. SIRSI offers a complete...system based on the Unicorn and BRS/ Search systems. The contracted STILAS package includes UNISYS hardware, software written in the C language

Analytic theory of orbit contraction and ballistic entry into planetary atmospheres

NASA Technical Reports Server (NTRS)

Longuski, J. M.; Vinh, N. X.

1980-01-01

A space object traveling through an atmosphere is governed by two forces: aerodynamic and gravitational. On this premise, equations of motion are derived to provide a set of universal entry equations applicable to all regimes of atmospheric flight from orbital motion under the dissipate force of drag through the dynamic phase of reentry, and finally to the point of contact with the planetary surface. Rigorous mathematical techniques such as averaging, Poincare's method of small parameters, and Lagrange's expansion, applied to obtain a highly accurate, purely analytic theory for orbit contraction and ballistic entry into planetary atmospheres. The theory has a wide range of applications to modern problems including orbit decay of artificial satellites, atmospheric capture of planetary probes, atmospheric grazing, and ballistic reentry of manned and unmanned space vehicles.

41 CFR 105-68.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are any procurement contracts included as covered transactions? 105-68.220 Section 105-68.220 Public Contracts and Property...) Covered Transactions § 105-68.220 Are any procurement contracts included as covered transactions? (a...

41 CFR 105-68.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Are any procurement contracts included as covered transactions? 105-68.220 Section 105-68.220 Public Contracts and Property...) Covered Transactions § 105-68.220 Are any procurement contracts included as covered transactions? (a...

48 CFR 19.602-4 - Awarding the contract.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Awarding the contract. 19.602-4 Section 19.602-4 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Certificates of Competency and Determinations of Responsibility...

48 CFR 705.207 - Preparation and transmittal of certain synopses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... INTERNATIONAL DEVELOPMENT ACQUISITION PLANNING PUBLICIZING CONTRACT ACTIONS Synopsis of Proposed Contract... notify USAID's Office of Small and Disadvantaged Business Utilization (OSDBU) at least seven business days before publicizing a solicitation in the Commerce Business Daily for an acquisition: (a) Which is...

77 FR 66052 - Program Access Rules

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-31

... contracts involving cable-affiliated programming; and amendments to its rules to ensure that buying groups utilized by small and medium-sized multichannel video programming distributors (``MVPDs'') can avail...-delivered) is entitled to a standstill of an existing programming contract during the pendency of a...

48 CFR 3413.107 - Solicitation and evaluation of quotations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Solicitation and evaluation of quotations. 3413.107 Section 3413.107 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES SMALL PURCHASE AND OTHER SIMPLIFIED...

12th Annual Small Business Conference

DTIC Science & Technology

2008-11-13

Joint Combat support systems. CoL myers graduated from marshall University in huntington, west virginia with a bachelors degree in Communications. he...as director and Principal assistant responsible for Contracting (ParC) for the Us army Contracting Command’s rock island Contracting Center (riCC...sustainment Command (asC) and the Joint munitions & Lethality Life Cycle management Command (Jm&L-LCmC) – rock island . in this position, he advises

Small Purchases.

DTIC Science & Technology

1982-01-01

excusable delay under "general contract law ". The Board went on to state that had the usual DAR default clause been present, it would have...that in Michigan the Board, in applying its "general contract law ", referenced the "usual DAR default clause" after the Board specifically recognized...Provisions through its "general contract law " principles in appropriate cases. In future cases the appropriate remedy may not be found in the Additional

48 CFR 52.232-40 - Providing Accelerated Payments to Small Business Subcontractors.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Payments to Small Business Subcontractors. 52.232-40 Section 52.232-40 Federal Acquisition Regulations... CLAUSES Text of Provisions and Clauses 52.232-40 Providing Accelerated Payments to Small Business... Contractor shall make accelerated payments to its small business subcontractors under this contract, to the...

48 CFR 252.219-7004 - Small business subcontracting plan (test program).

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Small business... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.219-7004 Small business subcontracting plan (test program). As prescribed in 219.708(b)(1)(B), use the following clause: Small Business...

48 CFR 252.219-7004 - Small business subcontracting plan (test program).

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Small business... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.219-7004 Small business subcontracting plan (test program). As prescribed in 219.708(b)(1)(B), use the following clause: Small Business...

48 CFR 19.301-2 - Rerepresentation by a contractor that represented itself as a small business concern.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Determination of Small Business Status for Small Business Programs 19.301-2 Rerepresentation by a contractor that... concern before contract award must rerepresent its size status for the North American Industry...

48 CFR 1519.201 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SMALL BUSINESS PROGRAMS Policies 1519.201 Policy. Each program's Assistant or Associate Administrator... developed in collaboration with the supporting Chiefs of Contracting Offices and the local Small Business Specialist (SBS), and the Office of Small and Disadvantaged Business Utilization (OSDBU). The goals will be...

49 CFR 26.39 - Fostering small business participation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 1 2012-10-01 2012-10-01 false Fostering small business participation. 26.39... BUSINESS ENTERPRISES IN DEPARTMENT OF TRANSPORTATION FINANCIAL ASSISTANCE PROGRAMS Administrative Requirements for DBE Programs for Federally-Assisted Contracting § 26.39 Fostering small business participation...

49 CFR 26.39 - Fostering small business participation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false Fostering small business participation. 26.39... BUSINESS ENTERPRISES IN DEPARTMENT OF TRANSPORTATION FINANCIAL ASSISTANCE PROGRAMS Administrative Requirements for DBE Programs for Federally-Assisted Contracting § 26.39 Fostering small business participation...

48 CFR 4.1201 - Policy.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 52.219-28, Post-Award Small Business Program Rerepresentation, apply, contractors that represented they were small businesses prior to award of a contract must update the representations and certifications in SAM as directed by the clause. Contractors that represented they were other than small...

48 CFR 4.1201 - Policy.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 52.219-28, Post-Award Small Business Program Rerepresentation, apply, contractors that represented they were small businesses prior to award of a contract must update the representations and certifications in SAM as directed by the clause. Contractors that represented they were other than small...

29 CFR 98.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 1 2011-07-01 2011-07-01 false Are any procurement contracts included as covered... SUSPENSION (NONPROCUREMENT) Covered Transactions § 98.220 Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded...

29 CFR 98.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Are any procurement contracts included as covered... SUSPENSION (NONPROCUREMENT) Covered Transactions § 98.220 Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded...

29 CFR 1471.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 4 2011-07-01 2011-07-01 false Are any procurement contracts included as covered... Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2) Do...

29 CFR 1471.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Are any procurement contracts included as covered... Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2) Do...

13 CFR 121.406 - How does a small business concern qualify to provide manufactured products or other supply items...

Code of Federal Regulations, 2013 CFR

2013-01-01

...-disabled veteran-owned small business set-aside, WOSB or EDWOSB set-aside, or 8(a) contract? 121.406... items under a small business set-aside, service-disabled veteran-owned small business set-aside, WOSB or... small business set-aside, service-disabled veteran-owned small business set-aside, WOSB or EDWOSB set...

13 CFR 121.406 - How does a small business concern qualify to provide manufactured products or other supply items...

Code of Federal Regulations, 2014 CFR

2014-01-01

...-disabled veteran-owned small business set-aside, WOSB or EDWOSB set-aside, or 8(a) contract? 121.406... items under a small business set-aside, service-disabled veteran-owned small business set-aside, WOSB or... small business set-aside, service-disabled veteran-owned small business set-aside, WOSB or EDWOSB set...

13 CFR 121.406 - How does a small business concern qualify to provide manufactured products or other supply items...

Code of Federal Regulations, 2012 CFR

2012-01-01

...-disabled veteran-owned small business set-aside, WOSB or EDWOSB set-aside, or 8(a) contract? 121.406... items under a small business set-aside, service-disabled veteran-owned small business set-aside, WOSB or... small business set-aside, service-disabled veteran-owned small business set-aside, WOSB or EDWOSB set...

Small Business Specialists.

DTIC Science & Technology

1997-12-01

located throughout the United States. Each service and agency has an Office of the Director of Small and Disadvantaged Business Utilization. They also...have small business specialists at each of their procurement and contract management offices to assist small businesses , small disadvantaged businesses ...and women-owned small businesses firms in marketing their products and services with the DoD. These specialists provide information and guidance on (1

2 CFR 180.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Are any procurement contracts included as... contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts awarded by non... expected to equal or exceed $25,000. (2) The contract requires the consent of an official of a Federal...

48 CFR 3019.705 - Responsibilities for the contracting officer under the subcontracting program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY ACQUISITION REGULATION (HSAR) SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting Program 3019.705...

SMALL BUSINESS: Status of Small Disadvantaged Business Certifications

DTIC Science & Technology

2001-01-01

Management and Budget. We will also make copies available to others on request.Page 13 GAO-01-273 Small Business If you have questions regarding this...GAO United States General Accounting OfficeReport to Congressional RequestersJanuary 2001 SMALL BUSINESS Status of Small Disadvantaged Business ...34) Title and Subtitle SMALL BUSINESS Status of Small Disadvantaged Business Certifications Contract or Grant Number Program Element Number Authors

Statements of work handbook. [technical writing for NASA programs

NASA Technical Reports Server (NTRS)

1975-01-01

Guidelines are presented for preparing statements of work (SOW) to assure a consistent approach throughout NASA. Statements of work for study and preliminary definition contracts, for definition and development of major systems, for support services, and for small research and development contracts are discussed.

13 CFR 124.504 - What circumstances limit SBA's ability to accept a procurement for award as an 8(a) contract?

Code of Federal Regulations, 2012 CFR

2012-01-01

... otherwise expressed publicly a clear intent to reserve the procurement as a small business set-aside, or a... whether rejection of the requirement would seriously reduce the pool of similar types of contracts...

13 CFR 124.504 - What circumstances limit SBA's ability to accept a procurement for award as an 8(a) contract?

Code of Federal Regulations, 2013 CFR

2013-01-01

... otherwise expressed publicly a clear intent to reserve the procurement as a small business set-aside, or a... whether rejection of the requirement would seriously reduce the pool of similar types of contracts...

Exploring Managerial Implications of Current DoD Contracting Trends

DTIC Science & Technology

2014-05-15

Shyu ASA(ALT), AAE, & SPE 7 Heads of Contracting Activity ( HCAs ) across the 7 Army buying commands Deputy Assistant Secretary of the Army...on commodity / portfolio Chair: DASA(P) Members: DASA(P) Deputy (Alternate-Chair) Senior Services Manager HCAs & PARCs / Alternates Small Business

Electronic Structure of Small Lanthanide Containing Molecules

NASA Astrophysics Data System (ADS)

Kafader, Jared O.; Ray, Manisha; Topolski, Josey E.; Chick Jarrold, Caroline

2016-06-01

Lanthanide-based materials have unusual electronic properties because of the high number of electronic degrees of freedom arising from partial occupation of 4f orbitals, which make these materials optimal for their utilization in many applications including electronics and catalysis. Electronic spectroscopy of small lanthanide molecules helps us understand the role of these 4f electrons, which are generally considered core-like because of orbital contraction, but are energetically similar to valence electrons. The spectroscopy of small lanthanide-containing molecules is relatively unexplored and to broaden this understanding we have completed the characterization of small cerium, praseodymium, and europium molecules using photoelectron spectroscopy coupled with DFT calculations. The characterization of PrO, EuH, EuO/EuOH, and CexOy molecules have allowed for the determination of their electron affinity, the assignment of numerous anion to neutral state transitions, modeling of anion/neutral structures and electron orbital occupation.

48 CFR 19.301-3 - Rerepresentation by a contractor that represented itself as other than a small business concern.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Determination of Small Business Status for Small Business Programs 19.301-3 Rerepresentation by a contractor... other than small before contract award may, but is not required to, rerepresent its size status when— (a...

76 FR 74749 - Small Business Subcontracting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-01

... amend its regulations to implement provisions of the Small Business Jobs Act of 2010 (Jobs Act... used in preparing its bid or proposal during contract performance. SBA also proposed to amend its... and evaluating small business subcontracting plan performance. SBA also proposed to clarify which...

5 CFR 919.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Are any procurement contracts included as...) Covered Transactions § 919.220 Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency...

Marine Corps Recruits: A Historical Look at Accessions and Bootcamp Performance

DTIC Science & Technology

2010-09-01

without the promise of an occupational field . Their code is PN, and these are called open contracts. In this slide, we graph the percentage of open ...means that occupational specialties such as infantry, armor, field artillery, and short-range air defense artillery are closed to women...enlistment contracts began for small numbers of Marines. While the 3 -, 4-, and 6-year initial enlistment contracts were open to the same group of MOSs

Evoked Potentials to Evaluate Mechanisms of Peripheral Nerve Repair.

DTIC Science & Technology

1980-02-01

brass bar. The tibial pin was clamped to vertical bars which in turn were adjustable and could be fixed to longitudinal runners. Muscle contraction was...each muscle contraction recording. After establishing stimulus threshold, supramaximal stimuli were spaced from 1.5 to 2.0 per second. A series of single...hour to 52 weeks after injury. Limbs with mobilized non- injured nerves sustained small but definite decreases in muscle contraction str:?ngth

48 CFR 1519.203 - Mentor-protege.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Mentor-protege. 1519.203... PROGRAMS SMALL BUSINESS PROGRAMS Policies 1519.203 Mentor-protege. (a) The Contracting officer shall insert the clause at 1552.219-70, Mentor-Protege Program, in all contracts under which the Contractor has...

Chemical sensors

DOEpatents

Lowell, Jr., James R.; Edlund, David J.; Friesen, Dwayne T.; Rayfield, George W.

1991-01-01

Sensors responsive to small changes in the concentration of chemical species are disclosed, comprising (a) a mechanochemically responsive polymeric film capable of expansion or contraction in response to a change in its chemical environment, operatively coupled to (b) a transducer capable of directly converting said expansion or contraction to a measurable electrical response.

Principles of Social Justice in Educational Research: The Case of Contract Research.

ERIC Educational Resources Information Center

Griffiths, Morwenna

1998-01-01

Delineates small-scale contract-research principles predicated on an understanding of social justice and of research purposes, epistemological issues, and possibilities for ethical and political action. Principles embrace improvement, knowledge and learning, changed belief systems, collaboration and consultation, openness to other communities,…

13 CFR 126.603 - Does HUBZone certification guarantee receipt of HUBZone contracts?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Does HUBZone certification guarantee receipt of HUBZone contracts? 126.603 Section 126.603 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION HUBZONE PROGRAM Contractual Assistance § 126.603 Does HUBZone certification...

48 CFR 419.508 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Standard and NAICS Code Information, in solicitations that are set aside for small businesses. [61 FR 53646... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Solicitation provisions and contract clauses. 419.508 Section 419.508 Federal Acquisition Regulations System DEPARTMENT OF...

48 CFR 719.273-11 - Solicitation provision and contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Solicitation provision and contract clause. 719.273-11 Section 719.273-11 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The U.S. Agency for International...

75 FR 8909 - Funding Opportunity Title: Commodity Partnerships for Small Agricultural Risk Management...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-26

... agreement program is to deliver training and information in management of production, marketing, and... ``* * * producers will be better able to use financial management, crop insurance, marketing contracts, and other... to use financial management, crop insurance, marketing contracts, and other existing and emerging...

48 CFR 719.273-11 - Solicitation provision and contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Solicitation provision and contract clause. 719.273-11 Section 719.273-11 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The U.S. Agency for International...

48 CFR 19.307 - Protesting a firm's status as a service-disabled veteran-owned small business concern.

Code of Federal Regulations, 2012 CFR

2012-10-01

... as a service-disabled veteran-owned small business concern. 19.307 Section 19.307 Federal Acquisition...-disabled veteran-owned small business concern. (a) For sole source acquisitions, the SBA or the contracting officer may protest the apparently successful offeror's service-disabled veteran-owned small business...

48 CFR 19.307 - Protesting a firm's status as a service-disabled veteran-owned small business concern.

Code of Federal Regulations, 2011 CFR

2011-10-01

... as a service-disabled veteran-owned small business concern. 19.307 Section 19.307 Federal Acquisition...-disabled veteran-owned small business concern. (a) For sole source acquisitions, the SBA or the contracting officer may protest the apparently successful offeror's service-disabled veteran-owned small business...

48 CFR 19.307 - Protesting a firm's status as a service-disabled veteran-owned small business concern.

Code of Federal Regulations, 2013 CFR

2013-10-01

... as a service-disabled veteran-owned small business concern. 19.307 Section 19.307 Federal Acquisition...-disabled veteran-owned small business concern. (a) For sole source acquisitions, the SBA or the contracting officer may protest the apparently successful offeror's service-disabled veteran-owned small business...

Strengthening Small Business Participation in Department of Defense Extramural Research and Development

DTIC Science & Technology

1983-01-01

Management , on "The Small Business Innovation...Development Act of 1982 and Department of Defense Small Business Research Programs" before the National Contract Management Association (NOVA Chapter), Arlington, VA, May 25, 1983. 511 ...STRENGTHENING SMALL BUSINESS PARTICIPATION IN DEPARTMENT OF DEFENSE EXTRAMURAL RESEARCH AND DEVELOPMENT Bernard K. Dennis, Defense

Counter-Unmanned Aerial Vehicle Warfare: Kill Authorizations for the Carrier Strike Group

DTIC Science & Technology

2016-06-10

COUNTER-UNMANNED AERIAL VEHICLE WARFARE: KILL AUTHORIZATIONS FOR THE CARRIER STRIKE GROUP A thesis presented to the Faculty...the Carrier Strike Group 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) LCDR Joshua C. Mattingly, U.S...including armed UAVs in an offensive role, but counter- UAV warfare is a new warfare area within the larger realm of air defense. Small Group 1 and 2

Sixth national stakeholder workshop summary report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

On June 17--18, 1998, the Department of Energy`s (DOE) Office of Worker and Community Transition convened its sixth National Stakeholder Workshop at the Ramada Plaza Hotel Old Town in Alexandria, Virginia. Approximately 325 stakeholders attended representing DOE headquarters and field offices, contractors, labor organizations, state and local government, education and community interest groups. The meeting addressed the progress made on the issues and challenges identified at the last stakeholder`s meeting in Oakland, California on April 9--11, 1997. Also discussed were the full range of the Department`s work force issues and creative solutions to the inherent challenges of simultaneously implementing themore » Department`s post Cold-War mission, work force restructuring guidance, contract reform objectives, asset disposition, performance-based management requirements, and business process improvement policies. The format of the Workshop included several plenary sessions and a number of small group discussion sessions. The small group sessions focused on topics related to labor issues, work force restructuring, work force planning, community transition, and employee concerns. The sessions provided a wide range of views on worker and community transition issues. The plenary sessions of the Workshop included presentations on the following topics: welcome and introductions; opening remarks; building a better labor-management relationship; keynote speech from Secretary of Energy Federico Pena; meeting tomorrow`s challenges (early site closures); harnessing the contracting process to encourage local growth; and, the British experience in economic conversion.« less

Small Business and Minority Contracting with the U.S. Government.

DTIC Science & Technology

1982-09-01

business tends to be marginally capitalized, generally with expensive short term financing (Hol lander, 1968). 3. Small business management is characterized...Forces of Small Business ." Journal of Small Business Management , January 1977, p. 30. Chism, David Meredith. A Critical Analysis of the Small Business ...Steinmetz, Lawrence L.; Kline, John B.; and Stegall, Donald P. Managing the Small Business . Homewood, lI].: Irwin, Inc.,

7 CFR 1466.21 - Contract requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., the participant must enter into a contract agreeing to implement one or more conservation practices. Technical services may be included in the contract. (b) An EQIP contract will: (1) Identify all conservation... agrees to assume all obligations, including operation and maintenance of the EQIP contract's conservation...

7 CFR 1466.21 - Contract requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., the participant must enter into a contract agreeing to implement one or more conservation practices. Technical services may be included in the contract. (b) An EQIP contract will: (1) Identify all conservation... agrees to assume all obligations, including operation and maintenance of the EQIP contract's conservation...

7 CFR 1466.21 - Contract requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., the participant must enter into a contract agreeing to implement one or more conservation practices. Technical services may be included in the contract. (b) An EQIP contract will: (1) Identify all conservation... agrees to assume all obligations, including operation and maintenance of the EQIP contract's conservation...

7 CFR 1466.21 - Contract requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., the participant must enter into a contract agreeing to implement one or more conservation practices. Technical services may be included in the contract. (b) An EQIP contract will: (1) Identify all conservation... agrees to assume all obligations, including operation and maintenance of the EQIP contract's conservation...

78 FR 59079 - Data Collection Available for Public Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-25

... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments ACTION: 60 Day Notice... announces the Small Business Administration's intentions to request approval on a new and/or currently... Government Contracting, Small Business Administration, 409 3rd Street, 8th Floor, Washington, DC 20416. FOR...

75 FR 18245 - Data Collection Available for Public Comments and Recommendations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-09

... SMALL BUSINESS ADMINISTRATION Data Collection Available for Public Comments and Recommendations..., this notice announces the Small Business Administration's intentions to request approval on a new and..., Office of Government Contracting, Small Business Administration, 409 3rd Street, 8th Floor, Washington...

Technical guide on documentation requirements for open market contract acquisitions of information resources

NASA Technical Reports Server (NTRS)

Shaw, Asa L., Jr.; Kivett, William R.; Taylor, James Y.

1990-01-01

A guide is presented to assist requestors in formulating and submitting the required Complete Package for Information Resources (IR) acquisitions. Advance discussions with cognizant procurement personnel are strongly recommended for complex IR requirements or for those requestors new to the acquisition process. Open Market means the requirement either is not available on GSA Schedule Contract or exceeds the $300,000 threshold and/or the quantity Maximum Order Limitation of the GSA Schedule Contract. Only open market contract acquisitions (i.e., in excess of the $25,000 small purchase threshold), are addressed.

Slow wave contraction frequency plateaus in the small intestine are composed of discrete waves of interval increase associated with dislocations.

PubMed

Parsons, Sean P; Huizinga, Jan D

2018-06-03

What is the central question of this study? What is the nature of slow wave driven contraction frequency gradients in the small intestine? What is the main finding and its importance? Frequency plateaus are composed of discrete waves of increased interval, each wave associated with a contraction dislocation. Smooth frequency gradients are generated by localised neural modulation of wave frequency, leading to functionally important wave turbulence. Both patterns are emergent properties of a network of coupled oscillators, the interstitial cells of Cajal. A gut-wide network of interstitial cells of Cajal (ICC) generate electrical oscillations (slow waves) that orchestrate waves of muscle contraction. In the small intestine there is a gradient in slow wave frequency from high at the duodenum to low at the terminal ileum. Time-averaged measurements of frequency have suggested either a smooth or stepped (plateaued) gradient. We measured individual contraction intervals from diameter maps of the mouse small intestine to create interval maps (IMaps). IMaps showed that each frequency plateau was composed of discrete waves of increased interval. Each interval wave originated at a terminating contraction wave, a "dislocation", at the plateau's proximal boundary. In a model chain of coupled phase oscillators, interval wave frequency increased as coupling decreased or as the natural frequency gradient or noise increased. Injuring the intestine at a proximal point to destroy coupling, suppressed distal steps which then reappeared with gap junction block by carbenoxolone. This lent further support to our previous hypothesis that lines of dislocations were fixed by points of low coupling strength. Dislocations induced by electrical field pulses in the intestine and by equivalent phase shift in the model, were associated with interval waves. When the enteric nervous system was active, IMaps showed a chaotic, turbulent pattern of interval change with no frequency steps or plateaus. This probably resulted from local, stochastic release of neurotransmitters. Plateaus, dislocations, interval waves and wave turbulence arise from a dynamic interplay between natural frequency and coupling in the ICC network. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

The development of a natural language interface to a geographical information system

NASA Technical Reports Server (NTRS)

Toledo, Sue Walker; Davis, Bruce

1993-01-01

This paper will discuss a two and a half year long project undertaken to develop an English-language interface for the geographical information system GRASS. The work was carried out for NASA by a small business, Netrologic, based in San Diego, California, under Phase 1 and 2 Small Business Innovative Research contracts. We consider here the potential value of this system whose current functionality addresses numerical, categorical and boolean raster layers and includes the display of point sets defined by constraints on one or more layers, answers yes/no and numerical questions, and creates statistical reports. It also handles complex queries and lexical ambiguities, and allows temporarily switching to UNIX or GRASS.

s-Process Branch Point (n,γ) Measurements using NIF^*

NASA Astrophysics Data System (ADS)

Bernstein, Lee; Bleuel, D. L.; Cerjan, C.; Greife, U.; Hoffman, R. D.; Phair, L.; McEvoy, A.; Moody, K. J.; Schneider, D. H. G.; Shaughnessy, D.; Stoyer, M. A.

2008-10-01

The National Ignition Facility (NIF) at LLNL is a laser-driven inertial confinement fusion laboratory designed to compress pellets containing small (<10^20 atoms) samples of material to densities in excess of 100 g/cm^3 and temperatures up to kBT 10 keV. Early NIF shots will feature a proton-tritium (HT) fuel mix that creates a neutron spectrum similar to that found in AGB main sequence stars. In this talk I will discuss nuclear physics experiments using NIF and present a plan to measure the ^171Tm(n,γ) s-process branch point cross section in a NIF plasma environment which will include the plasma-induced population of the first excited state at Ex=5.0 keV. *This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract W-7405-Eng-48 and under Contract DE-AC52-07NA27344. For LBNL this work was supported by the U.S. Department of Energy under Contract No. DE-AC02-05CH11231.

48 CFR 27.304-1 - General.

Code of Federal Regulations, 2011 CFR

2011-10-01

... at 52.227-11, Patent Rights—Ownership by the Contractor. (e) Government assignment to contractor of... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights under Government Contracts 27.304-1 General. (a.... (b) Exceptions. (1) Before using any of the exceptions under 27.303(e)(1) in a contract with a small...

48 CFR 27.304-1 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... at 52.227-11, Patent Rights—Ownership by the Contractor. (e) Government assignment to contractor of... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights under Government Contracts 27.304-1 General. (a.... (b) Exceptions. (1) Before using any of the exceptions under 27.303(e)(1) in a contract with a small...

75 FR 34291 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-42; Small Entity Compliance Guide

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-16

............ Disclosure and Consistency of Cost 2009-025 Chambers. Accounting Practices for Contracts Awarded to Foreign... of Cost Accounting Practices for Contracts Awarded to Foreign Concerns (FAR Case 2009-025) (Interim... Cost Accounting Standards (CAS) Board clause, Disclosure and Consistency of Cost Accounting Practices...

Chemical sensors

DOEpatents

Lowell, J.R. Jr.; Edlund, D.J.; Friesen, D.T.; Rayfield, G.W.

1991-07-02

Sensors responsive to small changes in the concentration of chemical species are disclosed. The sensors comprise a mechanochemically responsive polymeric film capable of expansion or contraction in response to a change in its chemical environment. They are operatively coupled to a transducer capable of directly converting the expansion or contraction to a measurable electrical response. 9 figures.

48 CFR 970.5227-10 - Patent rights-management and operating contracts, nonprofit organization or small business firm...

Code of Federal Regulations, 2011 CFR

2011-10-01

...-level nuclear waste and spent fuel technology; and (C) National security technologies classified or... Energy (DOE) Patent Counsel assisting the DOE contracting activity. (7) Practical application means to... inventions. (i) Inventions within or relating to the following fields of technology are exceptional...

48 CFR 970.5227-10 - Patent rights-management and operating contracts, nonprofit organization or small business firm...

Code of Federal Regulations, 2010 CFR

2010-10-01

...-level nuclear waste and spent fuel technology; and (C) National security technologies classified or... Energy (DOE) Patent Counsel assisting the DOE contracting activity. (7) Practical application means to... inventions. (i) Inventions within or relating to the following fields of technology are exceptional...

48 CFR 9903.202-1 - General requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... any small business concern. (b) Completed Disclosure Statements are required in the following circumstances: (1) Any business unit that is selected to receive a CAS-covered contract or subcontract of $50... the first CAS-covered contract is received within 90 days of the start of the cost accounting period...

75 FR 62257 - Women-Owned Small Business Federal Contract Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-07

... that, in industries in which WOSBs are underrepresented, two or more EDWOSBs will submit offers for the contract or, in industries where WOSBs are substantially underrepresented, two or more WOSBs will submit... view of the statute's explicit requirements, SBA cannot simply deem a NAICS code eligible under the...

48 CFR 1815.403-170 - Waivers of cost or pricing data.

Code of Federal Regulations, 2011 CFR

2011-10-01

... data when contracting for Small Business Innovation Research (SBIR) program Phase II contracts. However... data. 1815.403-170 Section 1815.403-170 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... 1815.403-170 Waivers of cost or pricing data. (a) NASA has waived the requirement for the submission of...

48 CFR 30.000 - Scope of part.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REQUIREMENTS COST ACCOUNTING STANDARDS ADMINISTRATION 30.000 Scope of part. This part describes policies and procedures for applying the Cost Accounting Standards Board (CASB) rules and regulations (48 CFR chapter 99... contracts or to any contract with a small business concern (see 48 CFR 9903.201-1(b) (FAR appendix) for...

Small Business Contracting Programs Parity Act of 2009

THOMAS, 111th Congress

Sen. Snowe, Olympia J. [R-ME

2009-07-21

Senate - 07/21/2009 Read twice and referred to the Committee on Small Business and Entrepreneurship. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

48 CFR 552.219-73 - Goals for Subcontracting Plan.

Code of Federal Regulations, 2012 CFR

2012-10-01

...: Goals for Subcontracting Plan (JUN 2005) (a) Maximum practicable utilization of small, HUBZone small... correct deficiencies in a plan within the time specified by the Contracting Officer shall make the offeror...

48 CFR 552.219-73 - Goals for Subcontracting Plan.

Code of Federal Regulations, 2014 CFR

2014-10-01

...: Goals for Subcontracting Plan (JUN 2005) (a) Maximum practicable utilization of small, HUBZone small... correct deficiencies in a plan within the time specified by the Contracting Officer shall make the offeror...

48 CFR 552.219-73 - Goals for Subcontracting Plan.

Code of Federal Regulations, 2013 CFR

2013-10-01

...: Goals for Subcontracting Plan (JUN 2005) (a) Maximum practicable utilization of small, HUBZone small... correct deficiencies in a plan within the time specified by the Contracting Officer shall make the offeror...

48 CFR 552.219-73 - Goals for Subcontracting Plan.

Code of Federal Regulations, 2011 CFR

2011-10-01

...: Goals for Subcontracting Plan (JUN 2005) (a) Maximum practicable utilization of small, HUBZone small... correct deficiencies in a plan within the time specified by the Contracting Officer shall make the offeror...

31 CFR 19.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Are any procurement contracts....220 Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2...

Mechanochemical symmetric breaking in cell motility of slime mold

NASA Astrophysics Data System (ADS)

Guy, Robert; Zhang, Shun; Del Alamo, Juan Carlos

2016-11-01

The cytoplasm of the true slime mold Physarum polycephalum exhibits regular rhythmic periodic shuttle streaming though the cell in the direction of motion. The fluid motion is driven by the periodic contraction of an actin-myosin gel that is regulated by a calcium oscillation. When the organism is small (< 100 microns) there is no shuttle streaming, but beyond this size, regular back-and-forth streaming appears and the cell begins to migrate. In this talk we analyze a mechanochemical model of the cell which includes the intracellular fluid, the active contractile cytoskeleton, the adhesion to the substrate, and the dynamics of a chemical oscillator. We use this analysis along with experimental data to identify the instability related to the onset of streaming in order to bring insight into how contraction, flow, and adhesion are coordinated during locomotion.

Heterogeneity of the neuropeptide Y (NPY) contractile and relaxing receptors in horse penile small arteries.

PubMed

Prieto, Dolores; Arcos, Luis Rivera de Los; Martínez, Pilar; Benedito, Sara; García-Sacristán, Albino; Hernández, Medardo

2004-12-01

The distribution of neuropeptide Y (NPY)-immunorective nerves and the receptors involved in the effects of NPY upon electrical field stimulation (EFS)- and noradrenaline (NA)-elicited contractions were investigated in horse penile small arteries. NPY-immunoreactive nerves were widely distributed in the erectile tissues with a particularly high density around penile intracavernous small arteries. In small arteries isolated from the proximal part of the corpora cavernosa, NPY (30 nM) produced a variable modest enhancement of the contractions elicited by both EFS and NA. At the same concentration, the NPY Y(1) receptor agonist, [Leu(31), Pro(34)]NPY, markedly potentiated responses to EFS and NA, whereas the NPY Y(2) receptor agonist, NPY(13-36), enhanced exogenous NA-induced contractions. In arteries precontracted with NA, NPY, peptide YY (PYY), [Leu(31), Pro(34)]NPY and the NPY Y(2) receptor agonists, N-acetyl[Leu(28,31)]NPY (24-36) and NPY(13-36), elicited concentration-dependent contractile responses. Human pancreatic polypeptide (hPP) evoked a biphasic response consisting of a relaxation followed by contraction. NPY(3-36), the compound 1229U91 (Ile-Glu-Pro-Dapa-Tyr-Arg-Leu-Arg-Tyr-NH2, cyclic(2,4')diamide) and eventually NPY(13-36) relaxed penile small arteries. The selective NPY Y(1) receptor antagonist BIBP3226 ((R)-N(2)-(diphenacetyl)-N-[(4-hydroxyphenyl)methyl]D-arginineamide) (0.3 microM) shifted to the right the concentration-response curves to both NPY and [Leu(31), Pro(34)]NPY and inhibited the contractions induced by the highest concentrations of hPP but not the relaxations observed at lower doses. In the presence of the selective NPY Y(2) receptor antagonist BIIE0246 ((S)-N2-[[1-[2-[4-[(R,S)-5,11-dihydro-6(6h)-oxodibenz[b,e]azepin-11-y1]-1-piperazinyl]-2-oxoethyl]cyclo-pentyl-N-[2-[1,2-dihydro-3,5 (4H)-dioxo-1,2-diphenyl-3H-1,2, 4-triazol-4-yl]ethyl]-argininamide) (0.3 microM), the Y(2) receptor agonists NPY(13-36) and N-acetyl[Leu(28,31)]NPY (24-36) evoked potent slow relaxations in NA-precontracted arteries, under conditions of nitric oxide (NO) synthase blockade. Mechanical removal of the endothelium markedly enhanced contractions of NPY on NA-precontracted arteries, whereas blockade of the neuronal voltage-dependent Ca(2+) channels did not alter NPY responses. These results demonstrate that NPY can elicit dual contractile/relaxing responses in penile small arteries through a heterogeneous population of postjunctional NPY receptors. Potentiation of the contractions evoked by NA involve both NPY Y(1) and NPY Y(2) receptors. An NO-independent relaxation probably mediated by an atypical endothelial NPY receptor is also shown and unmasked in the presence of selective antagonists of the NPY contractile receptors.