22 CFR 1508.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Are any procurement contracts included as... contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

High speed packet switching

NASA Technical Reports Server (NTRS)

1991-01-01

This document constitutes the final report prepared by Proteon, Inc. of Westborough, Massachusetts under contract NAS 5-30629 entitled High-Speed Packet Switching (SBIR 87-1, Phase 2) prepared for NASA-Greenbelt, Maryland. The primary goal of this research project is to use the results of the SBIR Phase 1 effort to develop a sound, expandable hardware and software router architecture capable of forwarding 25,000 packets per second through the router and passing 300 megabits per second on the router's internal busses. The work being delivered under this contract received its funding from three different sources: the SNIPE/RIG contract (Contract Number F30602-89-C-0014, CDRL Sequence Number A002), the SBIR contract, and Proteon. The SNIPE/RIG and SBIR contracts had many overlapping requirements, which allowed the research done under SNIPE/RIG to be applied to SBIR. Proteon funded all of the work to develop new router interfaces other than FDDI, in addition to funding the productization of the router itself. The router being delivered under SBIR will be a fully product-quality machine. The work done during this contract produced many significant findings and results, summarized here and explained in detail in later sections of this report. The SNIPE/RIG contract was completed. That contract had many overlapping requirements with the SBIR contract, and resulted in the successful demonstration and delivery of a high speed router. The development that took place during the SNIPE/RIG contract produced findings that included the choice of processor and an understanding of the issues surrounding inter processor communications in a multiprocessor environment. Many significant speed enhancements to the router software were made during that time. Under the SBIR contract (and with help from Proteon-funded work), it was found that a single processor router achieved a throughput significantly higher than originally anticipated. For this reason, a single processor router was developed and the final delivery under this contract will include a single processor CNX-500 router. The router and its interface boards (2 FDDIs and 2 dual-ethernets) are all product-quality components.

Customer relationship management in the contract pharmaceutical industry: an exploratory study for measuring success.

PubMed

Kros, John F; Nadler, Scott; Molis, Justin

2007-01-01

Managing customer relationships is a very important issue in business-to-business markets. This research investigates the growing number of available resources defining Customer Relationship Management (CRM) efforts, and how they are being applied within the Contract Pharmaceutical Manufacturing industry. Exploratory study results using face-to-face and telephone questionnaires based on four criteria for rating a company's CRM efforts are presented. Data was collected from large Contract Pharmaceutical Manufacturing companies in the US market. The results and conclusions are discussed relating how the Contract Pharmaceutical Manufacturing industry is implementing CRM including some potential steps to take when considering a CRM initiative.

Guidelines for cost control and analysis of cost-type research and development contracts

NASA Technical Reports Server (NTRS)

Sibbers, C. W.

1981-01-01

The cost information which should be obtained from a contractor(s) on a major, cost type research and development contract(s), and the analyses and effective use of these data are discussed. Specific type(s) of information which should be required, methods for analyzing such information, and methods for effectively using the results of such analyses to enhance NASA contract and project management are included. The material presented is based primarily on the principal methods which have been effectively used in the management of major cost type research and development contracts.

48 CFR 16.402-1 - Cost incentives.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracts (see 16.404 and 16.401 (e)), incentive contracts include a target cost, a target profit or fee... maximum fee) provides that— (1) Actual cost that meets the target will result in the target profit or fee; (2) Actual cost that exceeds the target will result in downward adjustment of target profit or fee...

48 CFR 16.402-1 - Cost incentives.

Code of Federal Regulations, 2011 CFR

2011-10-01

... contracts (see 16.404 and 16.401 (e)), incentive contracts include a target cost, a target profit or fee... maximum fee) provides that— (1) Actual cost that meets the target will result in the target profit or fee; (2) Actual cost that exceeds the target will result in downward adjustment of target profit or fee...

Creating a Full-thickness Choroidal Incision: An Ex Vivo Analysis of Human and Porcine Tissue Contraction Dynamics

PubMed Central

LoBue, Stephen A.; Yamada, Norihiro; Choi, Moon Jeong; Olsen, Timothy W.

2017-01-01

Purpose We hypothesized that the elastic nature of the choroid leads to tissue contraction following a full-thickness, sharp incision. Furthermore, we sought to quantify, measure, and compare tissue contraction in ex vivo porcine globes and human globes of various ages using predetermined variables. Method A full-thickness, ex vivo choroidal incision was performed in either pig (n = 97) or human (n = 30) specimens. Variables included trephine diameter (1.5, 2.0, or 2.5 mm) versus a straight surgical blade, and temperature (1.7 °–4.4° vs. 36.6°F). Central centripetal and surround centrifugal tissue contractions were measured. Mean percentage tissue contraction was assessed as a ratio of trephine diameter to final tissue contraction measured immediately following each incision using a standardized device. Results For trephination in pig specimens, centripetal contraction ranged from 38% to 50% with a mean of 44%. Centrifugal contraction was approximately 15%. Human choroidal contraction was 39% and 15%, respectively, with a statistically significant inverse relationship to age (R2 = 0.35, P ≤ 0.01). Asymmetric contraction was noted when incisions were closer to choroidal attachment sites to the sclera, such as near vortex ampullae. Linear incisions resulted in contraction that correlated with incision length (R2 = 0.35, P ≤ 0.001). Conclusions A full-thickness choroidal incision results in significant tissue contraction. For circular incisions, the centripetal contraction approaches 50% of the original incision size. For linear incisions, the contraction corresponds directly with incision length. In human specimens, there is less contraction with advancing age. Translational Relevance Our findings have clinical relevance for choroidal biopsy, traumatic injury, and choroidal translocation surgery. PMID:29134136

42 CFR 434.6 - General requirements for all contracts and subcontracts. P>(a) Contracts. All contracts under...

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 4 2011-10-01 2011-10-01 false General requirements for all contracts and subcontracts. P>(a) Contracts. All contracts under this part must include all of the following: 434.6 Section... contracts and subcontracts.P>(a) Contracts. All contracts under this part must include all of the following...

Evaluation of Ammunition Data Cards (REDACTED)

DTIC Science & Technology

2016-04-29

Procuring Contracting Officer ( PCO ), the manufacturer shall include, in the components sections on ADC representing the munition, all assemblies...lot components or evidence of PCO waiver approval. As a result, ADCs did not consistently include component items that make up the ammunition, and...Energetics PCO Procuring Contract Officer PQM Product Quality Manager QALI Quality Assurance Letter of Instruction QAR Quality Assurance Representative

The psychological contract: enhancing productivity and its implications for long-term care.

PubMed

Flannery, Raymond B

2002-01-01

When hired, a new employee is usually given a job description and an explanation of benefits. In addition, the employee will also have a psychological contract with the organization. This contract, often unstated, reflects the main source of the employee's motivation to work hard. This is true of all groups of employees, including long-term care staff. Common examples of psychological contracts for long-term care administrative staff include autonomy, social acceptance, and being in the forefront of cutting-edge research. An awareness of these psychological contracts can result in better "fits" between employee aspirations and relevant long-term care organization tasks so that productivity is enhanced. This article outlines the steps necessary to create these good fits in ways that benefit both the organization and its employees. These recommendations are of particular relevance to administrators and supervisors in long-term carefacilities.

22 CFR 1006.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Are any procurement contracts included as... DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 1006.220 Are any procurement contracts... procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

21 CFR 1404.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Are any procurement contracts included as covered... DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 1404.220 Are any procurement contracts... procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

21 CFR 1404.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Are any procurement contracts included as covered... DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 1404.220 Are any procurement contracts... procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

34 CFR 85.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Are any procurement contracts included as covered... DEBARMENT AND SUSPENSION (NONPROCUREMENT) Covered Transactions § 85.220 Are any procurement contracts... procurement contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-engineer contracts. 31.105 Section 31.105 Federal Acquisition Regulations System FEDERAL ACQUISITION... Construction and architect-engineer contracts. (a) This category includes all contracts and contract..., bridges, roads, or other kinds of real property. It also includes architect-engineer contracts related to...

Estimating user costs as a basis for incentive/disincentive amounts in highway construction contracts.

DOT National Transportation Integrated Search

1998-02-01

The Virginia Department of Transportation (VDOT) occasionally includes an incentive/ disincentive for early completion (I/D) in its construction contracts. This report presents the results of a project to identify procedures that would (1) enhance th...

48 CFR 1552.209-74 - Limitation of future contracting.

Code of Federal Regulations, 2014 CFR

2014-10-01

... preclude START contractors from performing construction management services under other EPA contracts. (3... Contracting Officer. Examples of such contracts include, but are not limited to, Superfund Management and... Contracting Officer. Examples of such contracts include, but are not limited to, Superfund Management and...

48 CFR 1552.209-74 - Limitation of future contracting.

Code of Federal Regulations, 2013 CFR

2013-10-01

... preclude START contractors from performing construction management services under other EPA contracts. (3... Contracting Officer. Examples of such contracts include, but are not limited to, Superfund Management and... Contracting Officer. Examples of such contracts include, but are not limited to, Superfund Management and...

Learning to Write in Braille: An Analysis of Writing Samples from Participants in the Alphabetic Braille and Contracted (ABC) Braille Study

ERIC Educational Resources Information Center

Erin, Jane N.; Wright, Tessa S.

2011-01-01

This article reports the results of data from 114 writing samples of 39 children who read braille and who were included in the Alphabetic Braille and Contracted Braille (ABC) Study between 2002 and 2005. Writing characteristics, miscues, and composition characteristics are analyzed, and two case studies are included. (Contains 1 box and 2 tables.)

41 CFR 105-68.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are any procurement contracts included as covered transactions? 105-68.220 Section 105-68.220 Public Contracts and Property...) Covered Transactions § 105-68.220 Are any procurement contracts included as covered transactions? (a...

41 CFR 105-68.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Are any procurement contracts included as covered transactions? 105-68.220 Section 105-68.220 Public Contracts and Property...) Covered Transactions § 105-68.220 Are any procurement contracts included as covered transactions? (a...

Driving to contract management in health care institutes of developing countries.

PubMed

Vatankhah, S; Barati, O; Maleki, M R; Tofighi, Sh; Rafii, S

2012-04-01

Public hospitals can privatize management activities by contracting with a private organization or person to perform the work. Management contract is a method which uses private sector for major government projects like hospitals. This study evaluates contract management in health care institutes of developing countries. Information has been collected by reviewing the management contract condition of selected countries. Different forms of public private partnership for private participation in hospitals were surveyed. The effects of management contract is expanding market opportunities to include public sector clients, capturing a market to be protected from competitors and providing a reliable and timely source of revenue. Contracting with non-governmental entities will provide better results than government provision of the same services. Contracting initiatives must be regulated and monitored at the highest level of government by experienced and astute policy makers, economists and operational personnel.

Violated and vulnerable: women's experiences of contracting a sexually transmitted infection from a male partner.

PubMed

East, Leah; Peters, Kath; Jackson, Debra

2017-08-01

To explore women's stories of contracting a sexually transmitted infection from a male partner and elucidate the gendered constructs and violence experienced that made the women vulnerable to these infections. Violence against women can result in both physical and psychological consequences and expose women to multiple health risks including sexual health adversity. Feminist storytelling approach. Qualitative interviews were conducted with 10 women. All data underwent thematic analysis. Findings from this study revealed the women were vulnerable to contracting sexually transmitted infection/s from their male sexual partners as a result of unequal gender and abusive relationship dynamics. Subsequently, contracting a sexual infection within this context potentially increased their vulnerability in both current and future relationships, through their loss of self-confidence and perceived ability to have a trusting loving heterosexual relationship as women with sexually transmitted infection/s. Women in relationships in which they are subordinate to their male partner are at heightened risk of sexual health adversity, including contracting a sexually transmitted infection. Contracting a sexually transmitted infection within the context of an abusive relationship can further increase women's vulnerability to dominant male partners, thus further exposure to sexual risk and adversity. Nurses working in clinical settings are well placed to conduct opportunistic screening of women's sexual health, including assessment of sexually transmitted infections and the nature of the encounter in which they were contracted. Thorough assessment can potentially identify relationship and personal factors that can increase a woman's risk to both sexual adversity and forms of abuse. Also, if women do divulge that they have suffered abuse, nurses are positioned to provide support and guidance in implementing strategies to minimise risk as well as referring them to specialised services. © 2017 John Wiley & Sons Ltd.

29 CFR 98.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 1 2011-07-01 2011-07-01 false Are any procurement contracts included as covered... SUSPENSION (NONPROCUREMENT) Covered Transactions § 98.220 Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded...

29 CFR 98.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Are any procurement contracts included as covered... SUSPENSION (NONPROCUREMENT) Covered Transactions § 98.220 Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded...

29 CFR 1471.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 4 2011-07-01 2011-07-01 false Are any procurement contracts included as covered... Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2) Do...

29 CFR 1471.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Are any procurement contracts included as covered... Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2) Do...

2 CFR 180.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Are any procurement contracts included as... contracts awarded directly by a Federal agency; but (2) Do include some procurement contracts awarded by non... expected to equal or exceed $25,000. (2) The contract requires the consent of an official of a Federal...

Insurance Contract Analysis for Company Decision Support in Acquisition Management

NASA Astrophysics Data System (ADS)

Chernovita, H. P.; Manongga, D.; Iriani, A.

2017-01-01

One of company activities to retain their business is marketing the products which include in acquisition management to get new customers. Insurance contract analysis using ID3 to produce decision tree and rules to be decision support for the insurance company. The decision tree shows 13 rules that lead to contract termination claim. This could be a guide for the insurance company in acquisition management to prevent contract binding with these contract condition because it has a big chance for the customer to terminate their insurance contract before its expired date. As the result, there are several strong points that could be the determinant of contract termination such as: 1) customer age whether too young or too old, 2) long insurance period (above 10 years), 3) big insurance amount, 4) big amount of premium charges, and 5) payment method.

NASA Extends Chandra Science and Operations Support Contract

NASA Astrophysics Data System (ADS)

2010-01-01

NASA has extended a contract with the Smithsonian Astrophysical Observatory in Cambridge, Mass., to provide science and operational support for the Chandra X-ray Observatory, a powerful tool used to better understand the structure and evolution of the universe. The contract extension with the Smithsonian Astrophysical Observatory provides continued science and operations support to Chandra. This approximately 172 million modification brings the total value of the contract to approximately 545 million for the base effort. The base effort period of performance will continue through Sept. 30, 2013, except for the work associated with the administration of scientific research grants, which will extend through Feb. 28, 2016. The contract type is cost reimbursement with no fee. In addition to the base effort, the contract includes two options for three years each to extend the period of performance for an additional six years. Option 1 is priced at approximately 177 million and Option 2 at approximately 191 million, for a total possible contract value of about $913 million. The contract covers mission operations and data analysis, which includes observatory operations, science data processing and astronomer support. The operations tasks include monitoring the health and status of the observatory and developing and uplinking the observation sequences during Chandra's communication coverage periods. The science data processing tasks include the competitive selection, planning and coordination of science observations and processing and delivery of the resulting scientific data. NASA's Marshall Space Flight Center in Huntsville, Ala, manages the Chandra program for the agency's Science Mission Directorate in Washington. The Smithsonian Astrophysical Observatory controls Chandra's science and flight operations. For more information about the Chandra X-ray Observatory visit: http://chandra.nasa.gov

Assessing Contract Management Maturity: U.S. Army Joint Munitions and Lethality Contracting Center, Army Contracting Command, Picatinny Arsenal

DTIC Science & Technology

2009-09-01

demonstrate competence” ( Jones , 2006). Most organizations conduct performance management for their employees with actions such as, setting goals...take the 14 form of comprehensive questionnaires, SWOT analyses or diagnostic models and include a comparison of results to various best practices...procnet.pica.army.mil/ Jones , R. (2006). CIDA Organizational Assessment Guide. Retrieved on March 1, 2009 from: http://www.acdi-cida.gc.ca/CIDAWEB

5 CFR 919.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Are any procurement contracts included as...) Covered Transactions § 919.220 Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency...

Aerobic metabolism on muscle contraction in porcine gastric smooth muscle.

PubMed

Kanda, Hidenori; Kaneda, Takeharu; Nagai, Yuta; Urakawa, Norimoto; Shimizu, Kazumasa

2018-05-18

Exposure to chronic hypoxic conditions causes various gastric diseases, including gastric ulcers. It has been suggested that gastric smooth muscle contraction is associated with aerobic metabolism. However, there are no reports on the association between gastric smooth muscle contraction and aerobic metabolism, and we have investigated this association in the present study. High K + - and carbachol (CCh)-induced muscle contractions involved increasing O 2 consumption. Aeration with N 2 (hypoxia) and NaCN significantly decreased high K + - and CCh-induced muscle contraction and O 2 consumption. In addition, hypoxia and NaCN significantly decreased creatine phosphate (PCr) contents in the presence of high K + . Moreover, decrease in CCh-induced contraction and O 2 consumption was greater than that of high K + . Our results suggest that hypoxia and NaCN inhibit high K + - and CCh-induced contractions in gastric fundus smooth muscles by decreasing O 2 consumption and intracellular PCr content. However, the inhibition of CCh-induced muscle contraction was greater than that of high K + -induced muscle contraction.

7 CFR 1466.21 - Contract requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., the participant must enter into a contract agreeing to implement one or more conservation practices. Technical services may be included in the contract. (b) An EQIP contract will: (1) Identify all conservation... agrees to assume all obligations, including operation and maintenance of the EQIP contract's conservation...

7 CFR 1466.21 - Contract requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., the participant must enter into a contract agreeing to implement one or more conservation practices. Technical services may be included in the contract. (b) An EQIP contract will: (1) Identify all conservation... agrees to assume all obligations, including operation and maintenance of the EQIP contract's conservation...

7 CFR 1466.21 - Contract requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., the participant must enter into a contract agreeing to implement one or more conservation practices. Technical services may be included in the contract. (b) An EQIP contract will: (1) Identify all conservation... agrees to assume all obligations, including operation and maintenance of the EQIP contract's conservation...

7 CFR 1466.21 - Contract requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., the participant must enter into a contract agreeing to implement one or more conservation practices. Technical services may be included in the contract. (b) An EQIP contract will: (1) Identify all conservation... agrees to assume all obligations, including operation and maintenance of the EQIP contract's conservation...

48 CFR 22.404-6 - Modifications of wage determinations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... solicitation, the contracting officer shall monitor the WDOL website to determine whether the applicable wage determination has been revised. Revisions published on the WDOL website or otherwise communicated to the... included in the resulting contract. Monitoring can be accomplished by use of the WDOL website's “Alert...

48 CFR 22.404-6 - Modifications of wage determinations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... solicitation, the contracting officer shall monitor the WDOL website to determine whether the applicable wage determination has been revised. Revisions published on the WDOL website or otherwise communicated to the... included in the resulting contract. Monitoring can be accomplished by use of the WDOL website's “Alert...

48 CFR 22.404-6 - Modifications of wage determinations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... solicitation, the contracting officer shall monitor the WDOL website to determine whether the applicable wage determination has been revised. Revisions published on the WDOL website or otherwise communicated to the... included in the resulting contract. Monitoring can be accomplished by use of the WDOL website's “Alert...

48 CFR 22.404-6 - Modifications of wage determinations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... solicitation, the contracting officer shall monitor the WDOL website to determine whether the applicable wage determination has been revised. Revisions published on the WDOL website or otherwise communicated to the... included in the resulting contract. Monitoring can be accomplished by use of the WDOL website's “Alert...

31 CFR 19.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Are any procurement contracts....220 Are any procurement contracts included as covered transactions? (a) Covered transactions under this part— (1) Do not include any procurement contracts awarded directly by a Federal agency; but (2...

NASA Extends Chandra X-ray Observatory Contract with the Smithsonian Astrophysical Observatory

NASA Astrophysics Data System (ADS)

2002-07-01

NASA NASA has extended its contract with the Smithsonian Astrophysical Observatory in Cambridge, Mass. to August 2003 to provide science and operational support for the Chandra X- ray Observatory, one of the world's most powerful tools to better understand the structure and evolution of the universe. The contract is an 11-month period of performance extension to the Chandra X-ray Center contract, with an estimated value of 50.75 million. Total contract value is now 298.2 million. The contract extension resulted from the delay of the launch of the Chandra X-ray Observatory from August 1998 to July 1999. The revised period of performance will continue the contract through Aug. 31, 2003, which is 48 months beyond operational checkout of the observatory. The contract type is cost reimbursement with no fee. The contract covers mission operations and data analysis, which includes both the observatory operations and the science data processing and general observer (astronomer) support. The observatory operations tasks include monitoring the health and status of the observatory and developing and distributing by satellite the observation sequences during Chandra's communication coverage periods. The science data processing tasks include the competitive selection, planning, and coordination of science observations with the general observers and the processing and delivery of the resulting scientific data. Each year, there are on the order of 200 to 250 observing proposals selected out of about 800 submitted, with a total amount of observing time about 20 million seconds. X-ray astronomy can only be performed from space because Earth's atmosphere blocks X-rays from reaching the surface. The Chandra Observatory travels one-third of the way to the Moon during its orbit around the Earth every 64 hours. At its highest point, Chandra's highly elliptical, or egg-shaped, orbit is 200 times higher than that of its visible-light- gathering sister, the Hubble Space Telescope. NASA's Marshall Space Flight Center, Huntsville, Ala., manages the Chandra Program for the Office of Space Science in Washington. The development contractor for the spacecraft was TRW, Inc., Redondo Beach, Calif. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge.

Final Technical Report for contract number DE-FG02-05ER15670

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glazebrook, Jane

This is the final technical report for contract number DE-FG02-05ER15670. The project is now complete, and results of the project have been published. Two papers were published based on work done in the last three-year funding period. The DOIs of these papers are included below. The abstracts of the papers, providing summaries of the work, are included in the body of the report.

Preferred supplier contracts in post-patent prescription drug markets.

PubMed

Blankart, Carl Rudolf; Stargardt, Tom

2016-02-22

In recent years, the expiration of patents for large drug classes has increased the importance of post-patent drug markets. However, previous research has focused solely on patent drug markets. In this study, the authors evaluate the influence of preferred supplier contracts, the German approach to tendering, in post-patent drug markets using a hierarchical market share attraction model. The authors find that preferred supplier contracts are a powerful strategic instrument for generic manufacturers in a highly competitive environment. They quantify the effects of signing a preferred supplier contract and show that brand-name manufacturers are vulnerable to tendering. Therefore, brand-name manufacturers should readjust their strategies and consider including preferred supplier contracts in their marketing mix. In addition, the authors employ a simulation to demonstrate that a first-mover advantage might be gained from signing a preferred supplier contract. Furthermore, their results can be used as a blueprint for decision makers in the pharmaceutical industry to assess the market share effects of different contracting strategies regarding preferred supplier contracts.

Reduction of construction wastes by improving construction contract management: a multinational evaluation.

PubMed

Mendis, Daylath; Hewage, Kasun N; Wrzesniewski, Joanna

2013-10-01

The Canadian construction industry generates 30% of the total municipal solid waste deposited in landfills. Ample evidence can be found in the published literature about rework and waste generation due to ambiguity and errors in contract documents. Also, the literature quotes that disclaimer clauses in contract documents are included in the contractual agreements to prevent contractor claims, which often cause rework. Our professional practice has also noted that there are several disclaimer clauses in standard contract documents which have the potential to cause rework (and associated waste). This article illustrates a comparative study of standard contractual documents and their potential to create rework (and associated waste) in different regions of the world. The objectives of this study are (1) to analyse standard contractual documents in Canada, the USA and Australia in terms of their potential to generate rework and waste, and (2) to propose changes/amendments to the existing standard contract documents to minimise/avoid rework. In terms of construction waste management, all the reviewed standard contract documents have deficiencies. The parties that produce the contract documents include exculpatory clauses to avoid the other party's claims. This approach tends to result in rework and construction waste. The contractual agreements/contract documents should be free from errors, deficiencies, ambiguity and unfair risk transfers to minimise/avoid potential to generate rework and waste.

41 CFR Appendix D to Part 60 - 741-Guidelines Regarding Positions Engaged in Carrying Out a Contract

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true 741-Guidelines Regarding... Management Other Provisions Relating to Public Contracts OFFICE OF FEDERAL CONTRACT COMPLIANCE PROGRAMS... performed and their relationship to contract performance. A position is included if its duties included work...

41 CFR Appendix D to Part 60 - 741-Guidelines Regarding Positions Engaged in Carrying Out a Contract

Code of Federal Regulations, 2012 CFR

2012-07-01

... 41 Public Contracts and Property Management 1 2012-07-01 2009-07-01 true 741-Guidelines Regarding... Management Other Provisions Relating to Public Contracts OFFICE OF FEDERAL CONTRACT COMPLIANCE PROGRAMS... performed and their relationship to contract performance. A position is included if its duties included work...

41 CFR Appendix D to Part 60 - 741-Guidelines Regarding Positions Engaged in Carrying Out a Contract

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 1 2011-07-01 2009-07-01 true 741-Guidelines Regarding... Management Other Provisions Relating to Public Contracts OFFICE OF FEDERAL CONTRACT COMPLIANCE PROGRAMS... performed and their relationship to contract performance. A position is included if its duties included work...

41 CFR Appendix D to Part 60 - 741-Guidelines Regarding Positions Engaged in Carrying Out a Contract

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 1 2013-07-01 2013-07-01 false 741-Guidelines Regarding... Management Other Provisions Relating to Public Contracts OFFICE OF FEDERAL CONTRACT COMPLIANCE PROGRAMS... performed and their relationship to contract performance. A position is included if its duties included work...

SPARTAN high resolution solar studies

NASA Technical Reports Server (NTRS)

Bruner, Marilyn E.

1993-01-01

This report summarizes the work performed on Contract NAS5-29739, a sub-orbital research program directed toward the study of the geometry of and physical conditions in matter found in the upper layers of the solar atmosphere. The report describes a new sounding rocket payload developed under the contract, presents a guide to the contents of semiannual reports submitted during the contract, discusses the results of the first flight of the payload and the progress on scientific analysis. A bibliography of papers and publications is included.

Male and Female Superintendents: A Comparison of Differences in Salaries, Interview Experiences, and Contract Negotiations

ERIC Educational Resources Information Center

Long, Alan

2010-01-01

This study reports the results of a comparison of differences in salary, interview experiences, and contract negotiations for male and female superintendents. Other variables of interest include educational attainment and educational experiences. The study participants (N = 161) consisted of practicing superintendents from four regions of the…

24 CFR 232.605 - Contract requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Fire Safety Equipment Form of Contract § 232.605 Contract requirements. (a) The contract between the... contract. Either form of contract shall include the cost of fire safety equipment, its installation, and...

24 CFR 232.605 - Contract requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Fire Safety Equipment Form of Contract § 232.605 Contract requirements. (a) The contract between the... contract. Either form of contract shall include the cost of fire safety equipment, its installation, and...

24 CFR 232.605 - Contract requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Fire Safety Equipment Form of Contract § 232.605 Contract requirements. (a) The contract between the... contract. Either form of contract shall include the cost of fire safety equipment, its installation, and...

Core-core and core-valence correlation

NASA Technical Reports Server (NTRS)

Bauschlicher, Charles W., Jr.; Langhoff, Stephen R.; Taylor, Peter R.

1988-01-01

The effect of (1s) core correlation on properties and energy separations was analyzed using full configuration-interaction (FCI) calculations. The Be 1 S - 1 P, the C 3 P - 5 S and CH+ 1 Sigma + or - 1 Pi separations, and CH+ spectroscopic constants, dipole moment and 1 Sigma + - 1 Pi transition dipole moment were studied. The results of the FCI calculations are compared to those obtained using approximate methods. In addition, the generation of atomic natural orbital (ANO) basis sets, as a method for contracting a primitive basis set for both valence and core correlation, is discussed. When both core-core and core-valence correlation are included in the calculation, no suitable truncated CI approach consistently reproduces the FCI, and contraction of the basis set is very difficult. If the (nearly constant) core-core correlation is eliminated, and only the core-valence correlation is included, CASSCF/MRCI approached reproduce the FCI results and basis set contraction is significantly easier.

Contract Design: Risk Management and Evaluation

PubMed Central

Amelung, Volker E.; Juhnke, Christin

2018-01-01

Introduction: Effective risk adjustment is an aspect that is more and more given weight on the background of competitive health insurance systems and vital healthcare systems. The risk structure of the providers plays a vital role in Pay for Performance. A prerequisite for optimal incentive-based service models is a (partial) dependence of the agent’s returns on the provider’s gain level. Integrated care systems as well as accountable care organisations (ACOs) in the US and similar concepts in other countries are advocated as an effective method of improving the performance of healthcare systems. These systems outline a payment and care delivery model that intends to tie provider reimbursements to predefined quality metrics. By this the total costs of care shall be reduced. Methods: Little is known about the contractual design and the main challenges of delegating “accountability” to these new kinds of organisations and/or contracts. The costs of market utilisation are highly relevant for the conception of healthcare contracts; furthermore information asymmetries and contract-specific investments are an obstacle to the efficient operation of ACOs. A comprehensive literature review on methods of designing contracts in Integrated Care was conducted. The research question in this article focuses on how reimbursement strategies, evaluation of measures and methods of risk adjustment can best be integrated in healthcare contracting. Results: Each integrated care contract includes challenges for both payers and providers without having sufficient empirical data on both sides. These challenges are clinical, administrative or financial nature. Risk adjusted contracts ensure that the reimbursement roughly matches the true costs resulting from the morbidity of a population. If reimbursement of care provider corresponds to the actual expenses for an individual/population the problem of risk selection is greatly reduced. The currently used methods of risk adjustment have widely differing model and forecast accuracy. For this reason, it is necessary to clearly regulate the method of risk adjustment in the integrated care contract. Conclusions and discussion: The series of three articles on contract design has shown that coordination and motivation problems in designing healthcare contracts cannot be solved at no-costs. Moreover, it became clear, that complete contracts in healthcare are unrealistic and that contracts do always include certain uncertainties. These are based on the risk of random, and no contracting party can control these risks completely. It is also not possible to fully integrate these risks in the contract or to eliminate these risks by the parties. PMID:29632454

Identifying Psychological Contract Breaches to Guide Improvements in Faculty Recruitment, Retention, and Development

PubMed Central

Desselle, Shane P.; Draugalis, JoLaine R.; Spies, Alan R.; Davis, Tamra S.; Bolino, Mark

2012-01-01

Objective. To identify pharmacy faculty members’ perceptions of psychological contract breaches that can be used to guide improvements in faculty recruitment, retention, and development. Methods. A list of psychological contract breaches was developed using a Delphi procedure involving a panel of experts assembled through purposive sampling. The Delphi consisted of 4 rounds, the first of which elicited examples of psychological contract breaches in an open-ended format. The ensuing 3 rounds consisting of a survey and anonymous feedback on aggregated group responses. Results. Usable responses were obtained from 11 of 12 faculty members who completed the Delphi procedure. The final list of psychological contract breaches included 27 items, after modifications based on participant feedback in subsequent rounds. Conclusion. The psychological contract breach items generated in this study provide guidance for colleges and schools of pharmacy regarding important aspects of faculty recruitment, retention, and development. PMID:22919084

Military Personnel Procurement Resources Report

DTIC Science & Technology

1991-05-28

directed at enlistment in the Military Service. Include cost of advertising agency contract spent on marketing research (to include cost of advertising...programs. Include cost of advertising agency contract spent on marketing research (to include cost of advertising agency subcontractors). 7. Printed...Include cost of advertising agency contract spent on marketing research (to include cost of advertising agency sub- contractors). 7. Printed

48 CFR 970.5070-3 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Extraordinary Contractual Actions and the..., shall be included in all management and operating contracts involving the risk of public liability for... the contract work, including such events caused by a product delivered to a DOE-owned, facility for...

76 FR 16388 - Fees for Reviews of the Rule Enforcement Programs of Contract Markets and Registered Futures...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-23

... charges fees to designated contract markets and registered futures associations to recover the costs..., as explained below. The FY 2010 fee includes adjustments to program costs incurred in FY 2008 and 2009, which are being revised as a result of an internal review of program costs. The FY 2010 fee...

26 CFR 1.451-5 - Advance payments for goods and long-term contracts.

Code of Federal Regulations, 2010 CFR

2010-04-01

... accounting for tax purposes if such method results in including advance payments in gross receipts no later... the case of a taxpayer accounting for advance payments for tax purposes pursuant to a long-term contract method of accounting under § 1.460-4, or of a taxpayer accounting for advance payments with...

Disentangling the effects of promised and delivered inducements: relational and transactional contract elements and the mediating role of trust.

PubMed

Montes, Samantha D; Irving, P Gregory

2008-11-01

Psychological contracts contain both relational and transactional elements, each of which is associated with unique characteristics. In the present research, the authors drew on these distinct qualities to develop and test hypotheses regarding differential employee reactions to underfulfillment, fulfillment, and overfulfillment of relational and transactional promises. Further, the authors extended their test of the theoretical distinctions between relational and transactional contracts by assessing the relevance of trust as a key underlying mechanism of relational and transactional psychological contract breach effects. Participants in this 3-wave longitudinal study included 342 full-time temporary employees. In support of existing theoretical distinctions, results indicated that employees reacted differently to varying levels of fulfillment of their relational and transactional contracts and that trust is a more central mechanism of relational, as opposed to transactional, psychological contract breach effects. These findings underscore L.S. Lambert, J. R. Edwards, and D. M. Cable's (2003) recent recommendation that the traditional conceptualization and study of psychological contract breach requires expansion.

The Joy of Contracts.

ERIC Educational Resources Information Center

Hegarty, Kevin

This paper is a practical guide that explains and illustrates contracts between libraries and vendors for computerized circulation systems. It describes the elements of a typical contract to include the equipment and services that should be specified in the contract and establishes scheduling and acceptance testing needs. Included in a contract…

48 CFR 23.804 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... refrigerant, such as air conditioners, including motor vehicles, refrigerators, chillers, or freezers. [61 FR... Equipment and Air Conditioners, in solicitations and contracts for services when the contract includes the...

NASA/UK TAP

NASA Technical Reports Server (NTRS)

1987-01-01

The purpose of the Technology Applications Program (TAP) is to provide problem solving information and assistance to both the public and private sectors in the Commonwealth of Kentucky, with emphasis primarily in the public sector. The TAP accesses over 1200 online computer databases, including files from the U.S., Canada, Europe, and Australia. During the 1985 to 1986 contract period, TAP responded to 645 inquiries which resulted in an increase of 16 percent over the 1984 to 1985 contract period. The activities of TAP for the 1985 to 1986 contract period are summarized.

Aries x ray objective grating spectrograph

NASA Technical Reports Server (NTRS)

Catura, R. C.

1991-01-01

This investigation was initiated in June of 1983. An Aries payload involving a single Wolter 1 telescope was developed and flown under a previous contract and the objective of this work was to add two additional mirrors, nested inside of the then existing mirror and add 12 objective reflection gratings to convert the telescope into a spectrograph. A summary of major milestones in the investigation are given. Results of efforts under this contract prior to 1987 are presented in the form of four reprints of published papers attached to this report. Results of the gamma-ray research are also included in the form of an attached reprint. A summary of other work under the contract since 1987 is given.

40 CFR 35.4235 - Are there specific provisions my group's contract(s) must contain?

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Suspension and Debarment; (g) The following clauses from 40 CFR 30.48: (1) Remedies for breaches of contract...'s contract(s) must contain? 35.4235 Section 35.4235 Protection of Environment ENVIRONMENTAL... provisions my group's contract(s) must contain? Your group must include the following provisions in each of...

48 CFR 1509.507-2 - Contract clause.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) solicitations and contracts, except Site Specific solicitations and contracts. The term “RAC” in the Limitation of Future Contracting clauses includes not only RAC solicitations and contracts but other long term..., except site specific solicitations and contracts. The term “ERRS” in the Limitation of Future Contracting...

48 CFR 1509.507-2 - Contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) solicitations and contracts, except Site Specific solicitations and contracts. The term “RAC” in the Limitation of Future Contracting clauses includes not only RAC solicitations and contracts but other long term..., except site specific solicitations and contracts. The term “ERRS” in the Limitation of Future Contracting...

48 CFR 1509.507-2 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) solicitations and contracts, except Site Specific solicitations and contracts. The term “RAC” in the Limitation of Future Contracting clauses includes not only RAC solicitations and contracts but other long term..., except site specific solicitations and contracts. The term “ERRS” in the Limitation of Future Contracting...

48 CFR 1509.507-2 - Contract clause.

Code of Federal Regulations, 2012 CFR

2012-10-01

...) solicitations and contracts, except Site Specific solicitations and contracts. The term “RAC” in the Limitation of Future Contracting clauses includes not only RAC solicitations and contracts but other long term..., except site specific solicitations and contracts. The term “ERRS” in the Limitation of Future Contracting...

Advanced transportation system studies. Technical area 2: Heavy lift launch vehicle development. Volume 2; Technical Results

NASA Technical Reports Server (NTRS)

1995-01-01

Sections 10 to 13 of the Advanced Transportation System Studies final report are included in this volume. Section 10 contains a copy of an executive summary that was prepared by Lockheed Space Operations Company (LSOC) to document their support to the TA-2 contract during the first-year period of performance of the contract, May 1992 through May 1993. LSOC participated on the TA-2 contract as part of the concurrent engineering launch system definition team, and provided outstanding heavy lift launch vehicle (HLLV) ground operations requirements and concept assessments for Lockheed Missiles and Space Company (LMSC) through an intercompany work transfer as well as providing specific HLLV ground operations assessments at the direction of NASA KSC through KSC funding that was routed to the TA-2 contract. Section 11 contains a copy of a vehicle-independent, launch system health management requirements assessment. The purpose of the assessment was to define both health management requirements and the associated interfaces between a generic advanced transportation system launch vehicle and all related elements of the entire transportation system, including the ground segment. Section 12 presents the major TA-2 presentations provided to summarize the significant results and conclusions that were developed over the course of the contract. Finally, Section 13 presents the design and assessment report on the first lunar outpost heavy lift launch vehicle.

Perceived barriers to utilizing maternal and neonatal health services in contracted-out versus government-managed health facilities in the rural districts of Pakistan

PubMed Central

Riaz, Atif; Zaidi, Shehla; Khowaja, Asif Raza

2015-01-01

Background: A number of developing countries have contracted out public health facilities to the Non-Government Organizations (NGOs) in order to improve service utilization. However, there is a paucity of in-depth qualitative information on barriers to access services as a result of contracting from service users’ perspective. The objective of this study was to explore perceived barriers to utilizing Maternal and Neonatal Health (MNH) services, in health facilities contracted out by government to NGO for service provision versus in those which are managed by government (non-contracted). Methods: A community-based qualitative exploratory study was conducted between April to September 2012 at two contracted-out and four matched non-contracted primary healthcare facilities in Thatta and Chitral, rural districts of Pakistan. Using semi-structured guide, the data were collected through thirty-six Focus Group Discussions (FGDs) conducted with mothers and their spouses in the catchment areas of selected facilities. Thematic analysis was performed using NVivo version 10.0 in which themes and sub-themes emerged. Results: Key barriers reported in contracted sites included physical distance, user charges and familial influences. Whereas, poor functionality of health centres was the main barrier for non-contracted sites with other issues being comparatively less salient. Decision-making patterns for participants of both catchments were largely similar. Spouses and mother-in-laws particularly influenced the decision to utilize health facilities. Conclusion: Contracting out of health facility reduces supply side barriers to MNH services for the community served but distance, user charges and low awareness remain significant barriers. Contracting needs to be accompanied by measures for transportation in remote settings, oversight on user fee charges by contractor, and strong community-based behavior change strategies. PMID:25905478

Community service contracting for older people in urban China: a case study in Guangdong Province.

PubMed

Lin, Wenyi

2016-01-01

Contracting of community services to non-governmental service-providing organisations - mainly social work agencies - is an emerging phenomenon and a social innovation with regard to delivering community services in urban China. Contracting of community services for the older person, which is the focus of this study, is embedded in the macro context of the development of social service contracting in China. Qualitative research techniques, including document analysis, case study, participant observation and in-depth interviews, were adopted for this study. Nine government officials, three staff working in Community Residents' Committees, 15 staff working in social work agencies and 41 older people were interviewed in an effort to understand the impact and challenges of community service contracting in urban China. The findings showed that the involvement of social work agencies in the community service provision system results in integration of community resources, expansion of service coverage and enhancement of older people's access to community services. However, several problems may impede the development of community service provision in the context of contracting in China. These include purchaser-oriented rather than user-oriented service provision, older people's negative attitude towards social work services, inappropriate performance measurement, reliance of non-government organisations on government funding and ambiguous definition of community services.

Galileon bounce after ekpyrotic contraction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Osipov, M.; Rubakov, V., E-mail: osipov@ms2.inr.ac.ru, E-mail: rubakov@ms2.inr.ac.ru

We consider a simple cosmological model that includes a long ekpyrotic contraction stage and smooth bounce after it. Ekpyrotic behavior is due to a scalar field with a negative exponential potential, whereas the Galileon field produces bounce. We give an analytical picture of how the bounce occurs within the weak gravity regime, and then perform numerical analysis to extend our results to a non-perturbative regime.

Contracting and Higher Education.

ERIC Educational Resources Information Center

Ferris, James M.

1991-01-01

The potential gains in efficiency of three types of contracts in college administration are contrasted. Contract types include explicit contracts in the budgeting process between the state and higher education institutions; institutional contracting for inputs; and interinstitutional contracting. The tradeoff between production cost savings and…

48 CFR 227.674 - Supply contracts between the Government and a foreign government or concern.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracts between the Government and a foreign government or concern. In negotiating contract prices with a second source, including the redetermination of contract prices, or in determining the allowability of... patent rights, rights in data, and other technical assistance provided to the second source, including...

48 CFR 546.312 - Construction contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Construction contracts... CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 546.312 Construction contracts. Insert the clause at 552.246-72, Final Inspection and Tests, in solicitations and contracts for construction that include...

48 CFR 546.312 - Construction contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Construction contracts... CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 546.312 Construction contracts. Insert the clause at 552.246-72, Final Inspection and Tests, in solicitations and contracts for construction that include...

48 CFR 546.312 - Construction contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Construction contracts... CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 546.312 Construction contracts. Insert the clause at 552.246-72, Final Inspection and Tests, in solicitations and contracts for construction that include...

48 CFR 546.312 - Construction contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Construction contracts... CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 546.312 Construction contracts. Insert the clause at 552.246-72, Final Inspection and Tests, in solicitations and contracts for construction that include...

NASA Northeast Regional Technology Transfer Center

NASA Technical Reports Server (NTRS)

Dunn, James P.

2001-01-01

This report is a summary of the primary activities and metrics for the NASA Northeast Regional Technology Transfer Center, operated by the Center for Technology Commercialization, Inc. (CTC). This report covers the contract period January 1, 2000 - March 31, 2001. This report includes a summary of the overall CTC Metrics, a summary of the Major Outreach Events, an overview of the NASA Business Outreach Program, a summary of the Activities and Results of the Technology into the Zone program, and a Summary of the Major Activities and Initiatives performed by CTC in supporting this contract. Between January 1, 2000 and March 31, 2001, CTC has facilitated 10 license agreements, established 35 partnerships, provided assistance 517 times to companies, and performed 593 outreach activities including participation in 57 outreach events. CTC also assisted Goddard in executing a successful 'Technology into the Zone' program.' CTC is pleased to have performed this contract, and looks forward to continue providing their specialized services in support of the new 5 year RTTC Contract for the Northeast region.

Exclusive contracts in the hospital setting: a two-edged sword, part 1: legal issues.

PubMed

Portman, Robert M

2007-05-01

Hospitals routinely enter into contracts with radiology groups for the right to be the exclusive provider of radiology services at the facility in exchange for the group agreeing to provide and manage all aspects of that service within the hospital. These "exclusive contracts" generally result in the radiology department and associated equipment being closed off to physicians who are not part of the contracting group. Exclusive contracts are generally considered to be good for physicians who have them and bad for those excluded by them. In fact, while exclusive contracts offer obvious benefits to the physicians who receive them and obvious disadvantages for those who are excluded, they also present pitfalls for physicians in the chosen group. Part I of this article discusses the legal issues raised by exclusive contracts. Although these agreements appear to be anti-competitive, most courts have rejected antitrust challenges to exclusive contracts. Excluded physicians have had much greater success in attacking exclusive contracting arrangements on breach of contract and procedural/due process grounds. Exclusive contracting arrangements can also raise concerns under the Medicare-Medicaid anti-kickback statute if the contracting physicians are required to pay consideration or accept less than fair market value compensation in exchange for exclusive contracts. These agreements can also raise issues under the Stark II physician self-referral law if the contracting physicians are in a position to refer Medicare or Medicaid patients to the hospital. Part II of this article will discuss the advantages and disadvantages of exclusive contracts for physicians covered and not covered by such contracts, as well as strategies for avoiding them or minimizing their potential adverse impact. It also will discuss specific provisions of exclusive contracts that should be included or avoided.

24 CFR 232.605 - Contract requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... MORTGAGE INSURANCE FOR NURSING HOMES, INTERMEDIATE CARE FACILITIES, BOARD AND CARE HOMES, AND ASSISTED... Fire Safety Equipment Form of Contract § 232.605 Contract requirements. (a) The contract between the... contract. Either form of contract shall include the cost of fire safety equipment, its installation, and...

48 CFR 870.111-3 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... officer shall include the clause at 852.270-2, Bread and bakery products—quantities, in solicitations and contracts for bread and bakery products. (b) The contracting officer shall include the clause at 852.270-3...

31 CFR 560.515 - 30-day delayed effective date for pre-May 7, 1995 trade contracts involving Iran.

Code of Federal Regulations, 2012 CFR

2012-07-01

...-May 7, 1995 trade contracts involving Iran. 560.515 Section 560.515 Money and Finance: Treasury....515 30-day delayed effective date for pre-May 7, 1995 trade contracts involving Iran. (a) All... involving Iran (a pre-existing trade contract), including the exportation of goods, services (including...

20 CFR 669.420 - What must be included in an on-the-job training contract?

Code of Federal Regulations, 2010 CFR

2010-04-01

... in an on-the-job training contract? At a minimum, an on-the-job training contract must comply with... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What must be included in an on-the-job training contract? 669.420 Section 669.420 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION...

Temporary agency contracts: what should they include?

PubMed

Sferrella, Sheila M

2002-01-01

The AHRA Board committed to provide some tools to help our members with agency contracts. This article provides the sections for a contract and what they should include. Of course, the language will have to comply with your organization's requirements. To comply with HIPAA regulations for contracts, I've also included language for business associates. JCAHO requires that the following documentation be on file for all contracted personnel: 1. Hospital job description or formal contract outlining the job responsibilities. 2. All licenses, certifications and registrations are reviewed and a process is developed to ensure that they remain current. 3. Competency is evaluated and maintained. 4. Evidence that personnel received a general orientation. 5. Evidence that personnel received a departmental orientation. 6. Safety and infection control standards must be met. In order to aid with compliance when utilizing contracted personnel, my organization developed a Contractor Personnel Administrative Compliance Checklist, which identifies requirements for compliance, a reference for assistance, and places to record that the requirement has been met for each of the areas listed in the previous item. Our standard contract includes sections on general definition of engagement, credentials and work experience; health, including immunization and drug testing; corporation; JCAHO; terms of the contract; and, non-disclosure of information. A business associate agreement may be necessary to comply with HIPAA regulations. Using the template has made my job much easier than trying to read each contract that crosses my desk. If an agency refuses to sign our contract, then we do not conduct business with that company. If an agency requests changes to the contract, depending on the language, we may or may not agree to it. This information is not intended to be legal advice, but rather an educational overview. As with any contract, the reader should consult with legal counsel at his or her organization.

48 CFR 46.201 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

....201 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Quality Requirements 46.201 General. (a) The contracting officer shall include in the solicitation and contract the appropriate quality requirements. The type and extent of contract quality...

Guidelines for Contracting Microfilming Services.

ERIC Educational Resources Information Center

Byrne, Sherry

1986-01-01

Outlines the process involved in selecting an outside filming agent for the purpose of preserving a library's or archive's holdings. Guidelines include project planning, selecting a filming agent, and contract preparation and maintenance. A sample contract is included. (Author/EM)

Residual Force Enhancement in Humans: A Systematic Review.

PubMed

Chapman, Neil; Whitting, John; Broadbent, Suzanne; Crowley-McHattan, Zachary; Meir, Rudi

2018-06-01

A systematic literature search was conducted to review the evidence of residual force enhancement (RFE) in vivo human muscle. The search, adhered to the PRISMA statement, of CINAHL, EBSCO, Embase, MEDLINE, and Scopus (inception-July 2017) was conducted. Full-text English articles that assessed at least 1 measure of RFE in vivo voluntarily contracted human skeletal muscle were selected. The methodologies of included articles were assessed against the Downs and Black checklist. Twenty-four studies were included (N = 424). Pooled Downs and Black scores ranked "fair" ([Formula: see text] [2.26]). RFE was observed in all muscles tested. Joint range of motion varied from 15° to 60°. Contraction intensities ranged from 10% to >95% maximum. Although transient force enhancement during the stretch phase may change with angular velocity, RFE in the subsequent isometric phase is independent of velocity. The magnitude of RFE was influenced by smaller stretch amplitudes and greatest at joint angles indicative of longer muscle lengths. Contraction and activation intensity influenced RFE, particularly during the initial isometric contraction phase of a poststretch isometric contraction. RFE resulted in increased torque production, reduced muscular activation, and enhanced torque production when the neuromuscular system is weakened seen in an aged population.

Differences in muscle activation patterns during pelvic floor muscle contraction and Valsalva maneuver.

PubMed

Thompson, Judith A; O'Sullivan, Peter B; Briffa, N Kathryn; Neumann, Patricia

2006-01-01

To investigate the different muscle activation patterns around the abdomino-pelvic cavity in continent women and their effect on pressure generation during a correct pelvic floor muscle (PFM) contraction and a Valsalva maneuver. Thirteen continent women were assessed. Abdominal, chest wall, and PFM activity and vaginal and intra-abdominal pressure (IAP), were recorded during two tasks: PFM contraction and Valsalva whilst bladder base position was monitored on trans-abdominal ultrasound. A correct PFM contraction was defined as one that resulted in bladder base elevation and a Valsalva resulted in bladder base depression. Comparison of the mean of the normalized EMG activity of all the individual muscle groups was significantly different between PFM contraction and Valsalva (P = 0.04). During a correct PFM contraction, the PFM were more active than during Valsalva (P = 0.001). During Valsalva, all the abdominal muscles (IO (P = 0.006), EO (P < 0.001), RA (P = 0.011)), and the chest wall (P < 0.001) were more active than during PFM contraction. The change in IAP was greater during Valsalva (P = 0.001) but there was no difference in the change in vaginal pressure between PFM contraction and Valsalva (P = 0.971). This study demonstrates a difference in muscle activation patterns between a correct PFM contraction and Valsalva maneuver. It is important to include assessment of the abdominal wall, chest wall, and respiration in the clinical evaluation of women performing PFM exercises as abdominal wall bracing combined with an increase in chest wall activity may cause rises in IAP and PFM descent. (c) 2005 Wiley-Liss, Inc.

Contract Design: Risk Management and Evaluation.

PubMed

Mühlbacher, Axel C; Amelung, Volker E; Juhnke, Christin

2018-01-12

Effective risk adjustment is an aspect that is more and more given weight on the background of competitive health insurance systems and vital healthcare systems. The risk structure of the providers plays a vital role in Pay for Performance. A prerequisite for optimal incentive-based service models is a (partial) dependence of the agent's returns on the provider's gain level. Integrated care systems as well as accountable care organisations (ACOs) in the US and similar concepts in other countries are advocated as an effective method of improving the performance of healthcare systems. These systems outline a payment and care delivery model that intends to tie provider reimbursements to predefined quality metrics. By this the total costs of care shall be reduced. Little is known about the contractual design and the main challenges of delegating "accountability" to these new kinds of organisations and/or contracts. The costs of market utilisation are highly relevant for the conception of healthcare contracts; furthermore information asymmetries and contract-specific investments are an obstacle to the efficient operation of ACOs. A comprehensive literature review on methods of designing contracts in Integrated Care was conducted. The research question in this article focuses on how reimbursement strategies, evaluation of measures and methods of risk adjustment can best be integrated in healthcare contracting. Each integrated care contract includes challenges for both payers and providers without having sufficient empirical data on both sides. These challenges are clinical, administrative or financial nature. Risk adjusted contracts ensure that the reimbursement roughly matches the true costs resulting from the morbidity of a population. If reimbursement of care provider corresponds to the actual expenses for an individual/population the problem of risk selection is greatly reduced. The currently used methods of risk adjustment have widely differing model and forecast accuracy. For this reason, it is necessary to clearly regulate the method of risk adjustment in the integrated care contract. The series of three articles on contract design has shown that coordination and motivation problems in designing healthcare contracts cannot be solved at no-costs. Moreover, it became clear, that complete contracts in healthcare are unrealistic and that contracts do always include certain uncertainties. These are based on the risk of random, and no contracting party can control these risks completely. It is also not possible to fully integrate these risks in the contract or to eliminate these risks by the parties.

48 CFR 31.105 - Construction and architect-engineer contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., include unallowable interest costs, or use improper cost of money rates or computations. Contracting... contracts, including cost-reimbursement subcontracts thereunder; (2) Negotiating indirect cost rates; (3... appropriate they serve to express the parties' understanding and avoid possible subsequent disputes or...

Contracts. Warranties.

ERIC Educational Resources Information Center

Mertz, Gayle

1988-01-01

Presents two lesson plans for grades 5-9 which are meant to increase student's legal literacy. The first lesson covers contracts and includes a comic strip which illustrates contract law. The second deals with warranties and why they are important. Included are examples of product warranties. (GEA)

Farmers' Preferences for PES Contracts to Adopt Silvopastoral Systems in Southern Ecuador, Revealed Through a Choice Experiment

NASA Astrophysics Data System (ADS)

Raes, Leander; Speelman, Stijn; Aguirre, Nikolay

2017-08-01

This study investigates farmers' preferences to participate in payment contracts to adopt silvopastoral systems in Ecuador. A choice experiment was used to elicit preferences between different contract attributes, including differing payment amounts and land management requirements. The research was carried out in the buffer zone of Podocarpus National Park in Southern Ecuador, an area where most land is dedicated to cattle husbandry. A choice experiment was conducted to measure farmers' interest in different types of contracts. Based on existing incentive programs, contract choices varied with respect to the type of silvopastoral system, extra land-use requirements, payment levels and contract duration. In addition, contracts differed with regards to access by cattle to streams. Although the farmers did not show strong preferences for every contract attribute, the majority of farmers in the area showed interest in the proposed contracts. A latent class model identified three classes of respondents, based on their preferences for different contracts attributes or the "business as usual" option. The results suggest that farmland area, agricultural income, and landowners' perceptions of environmental problems provide a partial explanation for the heterogeneity observed in the choices for specific contracts. Participation might increase if contracts were targeted at specific groups of farmers, such as those identified through our latent class model. Offering flexible contracts with varying additional requirements within the same scheme, involving farmers from the start in payments for environmental services design, and combining payments for environmental services with integrated conservation and development projects may be a better way to convince more farmers to adopt silvopastoral systems.

Farmers' Preferences for PES Contracts to Adopt Silvopastoral Systems in Southern Ecuador, Revealed Through a Choice Experiment.

PubMed

Raes, Leander; Speelman, Stijn; Aguirre, Nikolay

2017-08-01

This study investigates farmers' preferences to participate in payment contracts to adopt silvopastoral systems in Ecuador. A choice experiment was used to elicit preferences between different contract attributes, including differing payment amounts and land management requirements. The research was carried out in the buffer zone of Podocarpus National Park in Southern Ecuador, an area where most land is dedicated to cattle husbandry. A choice experiment was conducted to measure farmers' interest in different types of contracts. Based on existing incentive programs, contract choices varied with respect to the type of silvopastoral system, extra land-use requirements, payment levels and contract duration. In addition, contracts differed with regards to access by cattle to streams. Although the farmers did not show strong preferences for every contract attribute, the majority of farmers in the area showed interest in the proposed contracts. A latent class model identified three classes of respondents, based on their preferences for different contracts attributes or the "business as usual" option. The results suggest that farmland area, agricultural income, and landowners' perceptions of environmental problems provide a partial explanation for the heterogeneity observed in the choices for specific contracts. Participation might increase if contracts were targeted at specific groups of farmers, such as those identified through our latent class model. Offering flexible contracts with varying additional requirements within the same scheme, involving farmers from the start in payments for environmental services design, and combining payments for environmental services with integrated conservation and development projects may be a better way to convince more farmers to adopt silvopastoral systems.

48 CFR 342.302 - Contract administration functions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... functions. 342.302 Section 342.302 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Contract Administration Office Functions 342.302 Contract administration... services), will take place on HHS-owned or controlled properties. The clause shall not be included if...

48 CFR 342.302 - Contract administration functions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... functions. 342.302 Section 342.302 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Contract Administration Office Functions 342.302 Contract administration... services), will take place on HHS-owned or controlled properties. The clause shall not be included if...

48 CFR 342.302 - Contract administration functions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... functions. 342.302 Section 342.302 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Contract Administration Office Functions 342.302 Contract administration... services), will take place on HHS-owned or controlled properties. The clause shall not be included if...

48 CFR 342.302 - Contract administration functions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... functions. 342.302 Section 342.302 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Contract Administration Office Functions 342.302 Contract administration... services), will take place on HHS-owned or controlled properties. The clause shall not be included if...

Maintenance service contract model for heavy equipment in mining industry using principal agent theory

NASA Astrophysics Data System (ADS)

Pakpahan, Eka K. A.; Iskandar, Bermawi P.

2015-12-01

Mining industry is characterized by a high operational revenue, and hence high availability of heavy equipment used in mining industry is a critical factor to ensure the revenue target. To maintain high avaliability of the heavy equipment, the equipment's owner hires an agent to perform maintenance action. Contract is then used to control the relationship between the two parties involved. The traditional contracts such as fixed price, cost plus or penalty based contract studied is unable to push agent's performance to exceed target, and this in turn would lead to a sub-optimal result (revenue). This research deals with designing maintenance contract compensation schemes. The scheme should induce agent to select the highest possible maintenance effort level, thereby pushing agent's performance and achieve maximum utility for both parties involved. Principal agent theory is used as a modeling approach due to its ability to simultaneously modeled owner and agent decision making process. Compensation schemes considered in this research includes fixed price, cost sharing and revenue sharing. The optimal decision is obtained using a numerical method. The results show that if both parties are risk neutral, then there are infinite combination of fixed price, cost sharing and revenue sharing produced the same optimal solution. The combination of fixed price and cost sharing contract results in the optimal solution when the agent is risk averse, while the optimal combination of fixed price and revenue sharing contract is obtained when agent is risk averse. When both parties are risk averse, the optimal compensation scheme is a combination of fixed price, cost sharing and revenue sharing.

22 CFR 1508.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Are any procurement contracts included as covered transactions? 1508.220 Section 1508.220 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION.... (3) The contract is for federally-required audit services. ...

48 CFR 15.306 - Exchanges with offerors after receipt of proposals.

Code of Federal Regulations, 2011 CFR

2011-10-01

... negotiations may include bargaining. Bargaining includes persuasion, alteration of assumptions and positions... ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 15.... Negotiations are exchanges, in either a competitive or sole source environment, between the Government and...

48 CFR 15.306 - Exchanges with offerors after receipt of proposals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... negotiations may include bargaining. Bargaining includes persuasion, alteration of assumptions and positions... ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 15.... Negotiations are exchanges, in either a competitive or sole source environment, between the Government and...

Public Works Operations at U.S. Army Garrison-Yongsan, Korea

DTIC Science & Technology

2010-05-04

services to its customers in the most effective and efficient manner. We examined DPW contract actions of $5.9 million, purchases from the Prime...delivery orders to achieve maximum effectiveness and efficiency, which resulted in questionable costs of up to $924,000, including $79,851 in...internally consistent, contract actions are well documented, and inspections are complete and comprehensive; use the most cost- effective method for

Conditional Reasoning in Schizophrenic Patients.

PubMed

Kornreich, Charles; Delle-Vigne, Dyna; Brevers, Damien; Tecco, Juan; Campanella, Salvatore; Noël, Xavier; Verbanck, Paul; Ermer, Elsa

2017-01-01

Conditional reasoning (if p then q) is used very frequently in everyday situations. Conditional reasoning is impaired in brain-lesion patients, psychopathy, alcoholism, and polydrug dependence. Many neurocognitive deficits have also been described in schizophrenia. We assessed conditional reasoning in 25 patients with schizophrenia, 25 depressive patients, and 25 controls, using the Wason selection task in three different domains: social contracts, precautionary rules, and descriptive rules. Control measures included depression, anxiety, and severity of schizophrenia measures as a Verbal Intelligence Scale. Patients with schizophrenia were significantly impaired on all conditional reasoning tasks compared to depressives and controls. However, the social contract and precautions tasks yielded better results than the descriptive tasks. Differences between groups disappeared for social contract but remained for precautions and descriptive tasks when verbal intelligence was used as a covariate. These results suggest that domain-specific reasoning mechanisms, proposed by evolutionary psychologists, are relatively resilient in the face of brain network disruptions that impair more general reasoning abilities. Nevertheless, patients with schizophrenia could encounter difficulties understanding precaution rules and social contracts in real-life situations resulting in unwise risk-taking and misunderstandings in the social world.

48 CFR 17.107 - Options.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Options. 17.107 Section 17... CONTRACT TYPES SPECIAL CONTRACTING METHODS Multiyear Contracting 17.107 Options. Benefits may accrue by including options in a multiyear contract. In that event, contracting officers must follow the requirements...

48 CFR 217.204 - Contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

...)(i) Notwithstanding FAR 17.204(e), the ordering period of a task order or delivery order contract...) of this section does not apply to the following: (A) Contracts, including task or delivery order contracts, awarded under other statutory authority. (B) Advisory and assistance service task order contracts...

48 CFR 1847.7001 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... CONTRACT MANAGEMENT TRANSPORTATION Protection of the Florida Manatee 1847.7001 Contract clause. The contracting officer shall insert the clause at 1852.247-71, Protection of the Florida Manatee, in... the contract will involve use of waterways inhabited by manatees. The clause shall also be included in...

48 CFR 1847.7001 - Contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

... CONTRACT MANAGEMENT TRANSPORTATION Protection of the Florida Manatee 1847.7001 Contract clause. The contracting officer shall insert the clause at 1852.247-71, Protection of the Florida Manatee, in... the contract will involve use of waterways inhabited by manatees. The clause shall also be included in...

48 CFR 1847.7001 - Contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACT MANAGEMENT TRANSPORTATION Protection of the Florida Manatee 1847.7001 Contract clause. The contracting officer shall insert the clause at 1852.247-71, Protection of the Florida Manatee, in... the contract will involve use of waterways inhabited by manatees. The clause shall also be included in...

48 CFR 1847.7001 - Contract clause.

Code of Federal Regulations, 2012 CFR

2012-10-01

... CONTRACT MANAGEMENT TRANSPORTATION Protection of the Florida Manatee 1847.7001 Contract clause. The contracting officer shall insert the clause at 1852.247-71, Protection of the Florida Manatee, in... the contract will involve use of waterways inhabited by manatees. The clause shall also be included in...

48 CFR 1847.7001 - Contract clause.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CONTRACT MANAGEMENT TRANSPORTATION Protection of the Florida Manatee 1847.7001 Contract clause. The contracting officer shall insert the clause at 1852.247-71, Protection of the Florida Manatee, in... the contract will involve use of waterways inhabited by manatees. The clause shall also be included in...

Range contractions of the world's large carnivores

PubMed Central

2017-01-01

The majority of the world's terrestrial large carnivores have undergone substantial range contractions and many of these species are currently threatened with extinction. However, there has been little effort to fully quantify the extent of large carnivore range contractions, which hinders our ability to understand the roles and relative drivers of such trends. Here we present and analyse a newly constructed and comprehensive set of large carnivore range contraction maps. We reveal the extent to which ranges have contracted since historical times and identify regions and biomes where range contractions have been particularly large. In summary, large carnivores that have experienced the greatest range contractions include the red wolf (Canis rufus) (greater than 99%), Ethiopian wolf (Canis simensis) (99%), tiger (Panthera tigris) (95%) and lion (Panthera leo) (94%). In general, the greatest range contractions occurred in Southeastern Asia and Africa. Motivated by the ecological importance of intact large carnivore guilds, we also examined the spatial extent of intact large carnivore guilds both for the entire world and regionally. We found that intact carnivore guilds occupy just 34% of the world's land area. This compares to 96% in historic times. Spatial modelling of range contractions showed that contractions were significantly more likely in regions with high rural human population density, cattle density or cropland. Our results offer new insights into how best to prevent further range contractions for the world's largest carnivores, which will assist efforts to conserve these species and their important ecological effects. PMID:28791136

Range contractions of the world's large carnivores.

PubMed

Wolf, Christopher; Ripple, William J

2017-07-01

The majority of the world's terrestrial large carnivores have undergone substantial range contractions and many of these species are currently threatened with extinction. However, there has been little effort to fully quantify the extent of large carnivore range contractions, which hinders our ability to understand the roles and relative drivers of such trends. Here we present and analyse a newly constructed and comprehensive set of large carnivore range contraction maps. We reveal the extent to which ranges have contracted since historical times and identify regions and biomes where range contractions have been particularly large. In summary, large carnivores that have experienced the greatest range contractions include the red wolf ( Canis rufus ) (greater than 99%), Ethiopian wolf ( Canis simensis ) (99%), tiger ( Panthera tigris ) (95%) and lion ( Panthera leo ) (94%). In general, the greatest range contractions occurred in Southeastern Asia and Africa. Motivated by the ecological importance of intact large carnivore guilds, we also examined the spatial extent of intact large carnivore guilds both for the entire world and regionally. We found that intact carnivore guilds occupy just 34% of the world's land area. This compares to 96% in historic times. Spatial modelling of range contractions showed that contractions were significantly more likely in regions with high rural human population density, cattle density or cropland. Our results offer new insights into how best to prevent further range contractions for the world's largest carnivores, which will assist efforts to conserve these species and their important ecological effects.

Mitigating Provider Uncertainty in Service Provision Contracts

NASA Astrophysics Data System (ADS)

Smith, Chris; van Moorsel, Aad

Uncertainty is an inherent property of open, distributed and multiparty systems. The viability of the mutually beneficial relationships which motivate these systems relies on rational decision-making by each constituent party under uncertainty. Service provision in distributed systems is one such relationship. Uncertainty is experienced by the service provider in his ability to deliver a service with selected quality level guarantees due to inherent non-determinism, such as load fluctuations and hardware failures. Statistical estimators utilized to model this non-determinism introduce additional uncertainty through sampling error. Inability of the provider to accurately model and analyze uncertainty in the quality level guarantees can result in the formation of sub-optimal service provision contracts. Emblematic consequences include loss of revenue, inefficient resource utilization and erosion of reputation and consumer trust. We propose a utility model for contract-based service provision to provide a systematic approach to optimal service provision contract formation under uncertainty. Performance prediction methods to enable the derivation of statistical estimators for quality level are introduced, with analysis of their resultant accuracy and cost.

10 CFR 600.148 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Contract provisions. 600.148 Section 600.148 Energy... Nonprofit Organizations Post-Award Requirements § 600.148 Contract provisions. The recipient shall include... contracts. The following provisions shall also be applied to subcontracts. (a) Contracts in excess of the...

14 CFR 1274.509 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... breaches the contract terms, and provide for such remedial actions as may be appropriate. (b) All contracts... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Contract provisions. 1274.509 Section 1274... COMMERCIAL FIRMS Procurement Standards § 1274.509 Contract provisions. The recipient shall include, in...

Bibliography of Lewis Research Center technical contributions announced in 1976

NASA Technical Reports Server (NTRS)

1977-01-01

Abstracts of Lewis authored publications and publications resulting from Lewis managed contracts which were announced in the 1976 issues of STAR (Scientific and Technical Aerospace Reports) and IAA (International Aerospace Abstracts) are presented. Research reports, journal articles, conference presentations, patents and patent applications, and these are included. The arrangement is by NASA subject category. Citations indicate report literature (identified by their N-numbers) and the journal and conference presentations (identified by their A-numbers). A grouping of indexes helps locate specific publications by author (including contractor authors), contractor organization, contract number, and report number.

The Use of Contract Grading in the First College Speech Course

ERIC Educational Resources Information Center

Subeck, Ronald H.

1973-01-01

Describes an introductory, college level speech course based on contract grading. Includes the requirements for the various grades, student reactions to contract grading, the grade contract, and a twelve item bibliography. (DD)

Overview of the NASA/RECON educational, research, and development activities of the Computer Science Departments of the University of Southwestern Louisiana and Southern University

NASA Technical Reports Server (NTRS)

Dominick, Wayne D. (Editor)

1984-01-01

This document presents a brief overview of the scope of activities undertaken by the Computer Science Departments of the University of Southern Louisiana (USL) and Southern University (SU) pursuant to a contract with NASA. Presented are only basic identification data concerning the contract activities since subsequent entries within the Working Paper Series will be oriented specifically toward a detailed development and presentation of plans, methodologies, and results of each contract activity. Also included is a table of contents of the entire USL/DBMS NASA/RECON Working Paper Series.

[The use of management contracts and professional incentives in the public health sector].

PubMed

Ditterich, Rafael Gomes; Moysés, Simone Tetu; Moysés, Samuel Jorge

2012-04-01

Results-based management is a cornerstone of reform in public administration, including the health field, and has become the basis for other innovations such as the institutionalization of management contracts and the use of professional incentives. This review article aims to introduce and discuss the use of such management contracts in the public health sector. Management by results has developed means and tools that highlight the importance of shared responsibility and mutual commitment between workers and management-level directors. Thus, preset goals are negotiated among all the stakeholders and are evaluated periodically in order to grant professional incentives. It is necessary to improve the mechanisms for control and observation, to more precisely determine the healthcare and management indicators and their patterns, to train stakeholders in designing the plan, and to improve the use of professional incentives in order to effectively increase accountability vis-à-vis the desired results.

48 CFR 205.303 - Announcement of contract awards.

Code of Federal Regulations, 2014 CFR

2014-10-01

... (if significant work is performed at a different location); (4) Funding data. Type of appropriation... DD-LA- (AR) 1279; (D) Including, as a minimum, the following— (1) Contract data. Contract number... contract, description of what is being bought, contract type, whether any of the buy was for foreign...

48 CFR 205.303 - Announcement of contract awards.

Code of Federal Regulations, 2013 CFR

2013-10-01

... (if significant work is performed at a different location); (4) Funding data. Type of appropriation... DD-LA- (AR) 1279; (D) Including, as a minimum, the following— (1) Contract data. Contract number... contract, description of what is being bought, contract type, whether any of the buy was for foreign...

48 CFR 205.303 - Announcement of contract awards.

Code of Federal Regulations, 2011 CFR

2011-10-01

... (if significant work is performed at a different location); (4) Funding data. Type of appropriation... DD-LA- (AR) 1279; (D) Including, as a minimum, the following— (1) Contract data. Contract number... contract, description of what is being bought, contract type, whether any of the buy was for foreign...

48 CFR 205.303 - Announcement of contract awards.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (if significant work is performed at a different location); (4) Funding data. Type of appropriation... DD-LA- (AR) 1279; (D) Including, as a minimum, the following— (1) Contract data. Contract number... contract, description of what is being bought, contract type, whether any of the buy was for foreign...

48 CFR 205.303 - Announcement of contract awards.

Code of Federal Regulations, 2012 CFR

2012-10-01

... (if significant work is performed at a different location); (4) Funding data. Type of appropriation... DD-LA- (AR) 1279; (D) Including, as a minimum, the following— (1) Contract data. Contract number... contract, description of what is being bought, contract type, whether any of the buy was for foreign...

48 CFR 52.228-15 - Performance and Payment Bonds-Construction.

Code of Federal Regulations, 2010 CFR

2010-10-01

...) Definitions. As used in this clause— Original contract price means the award price of the contract; or, for requirements contracts, the price payable for the estimated total quantity; or, for indefinite-quantity contracts, the price payable for the specified minimum quantity. Original contract price does not include...

Adrenergic ligands that block oviposition in the cattle tick Rhipicephalus microplus affect ovary contraction

PubMed Central

Cossío-Bayúgar, Raquel; Miranda-Miranda, Estefan; Fernández-Rubalcaba, Manuel; Narváez Padilla, Verónica; Reynaud, Enrique

2015-01-01

The tyraminergic/octopaminergic system is central for the control of arthropod oviposition. Previous works demonstrated that the pharmacological perturbation of this system inhibits oviposition in the cattle tick Rhipicephalus microplus. In this work, we describe a physiologically active whole-mount preparation of the contractile tick ovary that allows the quantitative videometrical analysis of ovary contraction in response to different compounds. Eight adrenergic ligands known to inhibit oviposition, including octopamine and tyramine were tested. These compounds exhibited antagonistic effects; octopamine relaxes the ovary preparation while tyramine induces a very strong contraction. The other adrenergic compounds tested were classified as able to contract or relax ovary muscle tissue. Isoprotenerol has a stronger relaxative effect than octopamine. Tyramine induces the biggest contraction observed of all the compounds tested, followed, in descending amount of contraction, by salbutamol, prazosin, epinastine, clonidine and the acaricide amitraz. The effect of these adrenergic ligands on the ovary preparation, explains why these molecules inhibit tick oviposition and suggest a regulatory mechanism for ovary contraction and relaxation during oviposition. Our results also provide a physiological explanation of the egg-laying inhibition effect of amitraz when used on the cattle tick. PMID:26456007

Adrenergic ligands that block oviposition in the cattle tick Rhipicephalus microplus affect ovary contraction.

PubMed

Cossío-Bayúgar, Raquel; Miranda-Miranda, Estefan; Fernández-Rubalcaba, Manuel; Narváez Padilla, Verónica; Reynaud, Enrique

2015-10-12

The tyraminergic/octopaminergic system is central for the control of arthropod oviposition. Previous works demonstrated that the pharmacological perturbation of this system inhibits oviposition in the cattle tick Rhipicephalus microplus. In this work, we describe a physiologically active whole-mount preparation of the contractile tick ovary that allows the quantitative videometrical analysis of ovary contraction in response to different compounds. Eight adrenergic ligands known to inhibit oviposition, including octopamine and tyramine were tested. These compounds exhibited antagonistic effects; octopamine relaxes the ovary preparation while tyramine induces a very strong contraction. The other adrenergic compounds tested were classified as able to contract or relax ovary muscle tissue. Isoprotenerol has a stronger relaxative effect than octopamine. Tyramine induces the biggest contraction observed of all the compounds tested, followed, in descending amount of contraction, by salbutamol, prazosin, epinastine, clonidine and the acaricide amitraz. The effect of these adrenergic ligands on the ovary preparation, explains why these molecules inhibit tick oviposition and suggest a regulatory mechanism for ovary contraction and relaxation during oviposition. Our results also provide a physiological explanation of the egg-laying inhibition effect of amitraz when used on the cattle tick.

Biomedicine, holism and general medical practice: responses to the 2004 General Practitioner contract.

PubMed

Checkland, Kath; Harrison, Stephen; McDonald, Ruth; Grant, Suzanne; Campbell, Stephen; Guthrie, Bruce

2008-07-01

In 2004 a new contract was introduced for General Practitioners in the UK, which introduced a significant element of 'pay-for-performance', including both clinical and organisational targets. The introduction of this contract has caused interest across the world, particularly amongst those responsible for commissioning primary care services. It can be argued that the clinical targets in the contract (known as the Quality and Outcomes Framework, QOF) represent a move towards a more biomedical model of health and illness, which is contrary to the ideal of providing holistic (or biopsychosocial) care that has been traditionally espoused by GPs. This paper reports results from two linked studies (in England and Scotland) investigating the early stages of the new contract. We describe the way in which four practices with different organisational approaches and espoused identities have all changed their practice structures, consultations and clinical care in response to QOF in ways which will result in patients receiving a more biomedical type of care. In spite of these observed changes, respondents continued to maintain discursive claims to holism. We discuss how this disconnection between rhetoric and reality can be maintained, and consider its implications for the future development of GPs' claims to a professional identity.

Tips for a physician in getting the right job, Part XX: more comments on employment contracts.

PubMed

Harolds, Jay A

2015-03-01

This article discusses a variety of important employment contract issues. This includes remuneration, fringe benefits, and time off. It also includes dispute resolution and the protection of assets and information. Several types of restrictive covenants are also discussed. This information should be useful to job seekers attempting to understand contracts. However, all employment contracts should be discussed with the job seeker's attorney before signing it.

Endogenous Cardiac Troponin T Modulates Ca2+-Mediated Smooth Muscle Contraction

PubMed Central

Kajioka, Shunichi; Takahashi-Yanaga, Fumi; Shahab, Nouval; Onimaru, Mitsuho; Matsuda, Miho; Takahashi, Ryosuke; Asano, Haruhiko; Morita, Hiromitsu; Morimoto, Sachio; Yonemitsu, Yoshikazu; Hayashi, Maya; Seki, Narihito; Sasaguri, Toshiuyki; Hirata, Masato; Nakayama, Shinsuke; Naito, Seiji

2012-01-01

Mechanisms linked to actin filaments have long been thought to cooperate in smooth muscle contraction, although key molecules were unclear. We show evidence that cardiac troponin T (cTnT) substantially contributes to Ca2+-mediated contraction in a physiological range of cytosolic Ca2+ concentration ([Ca2+]i). cTnT was detected in various smooth muscles of the aorta, trachea, gut and urinary bladder, including in humans. Also, cTnT was distributed along with tropomyosin in smooth muscle cells, suggesting that these proteins are ready to cause smooth muscle contraction. In chemically permeabilised smooth muscle of cTnT+/− mice in which cTnT reduced to ~50%, the Ca2+-force relationship was shifted toward greater [Ca2+]i, indicating a sizeable contribution of cTnT to smooth muscle contraction at [Ca2+]i < 1 μM. Furthermore, addition of supplemental TnI and TnC reconstructed a troponin system to enhance contraction. The results indicated that a Tn/Tn-like system on actin-filaments cooperates together with the thick-filament pathway. PMID:23248744

Options for change in the NHS consultant contract.

PubMed

Clarke, R W; Gray, C

The lead negotiators for the management and consultant sides in an NHS trust in northern England responded to debate in their trust about consultant contracts by offering to research the attitudes of their peers towards a variety of contract options. The options tested included the current contract; models already examined in the trust and elsewhere, such as time sensitive and mild performance related contracts; and some more radical and speculative possibilities, including consultants franchising their services to the trust. Beyond the predictable conclusion that consultants would prefer no change while managers desired it, a time sensitive contract emerged as having potential for successful negotiation. On the other hand, neither consultants nor managers favoured a strict performance related contract or a fee for service contract. There was a strong similarity of opinion between the two groups on the relative salary values of the options, though the consultants consistently priced these higher than the managers.

Options for change in the NHS consultant contract.

PubMed Central

Clarke, R. W.; Gray, C.

1994-01-01

The lead negotiators for the management and consultant sides in an NHS trust in northern England responded to debate in their trust about consultant contracts by offering to research the attitudes of their peers towards a variety of contract options. The options tested included the current contract; models already examined in the trust and elsewhere, such as time sensitive and mild performance related contracts; and some more radical and speculative possibilities, including consultants franchising their services to the trust. Beyond the predictable conclusion that consultants would prefer no change while managers desired it, a time sensitive contract emerged as having potential for successful negotiation. On the other hand, neither consultants nor managers favoured a strict performance related contract or a fee for service contract. There was a strong similarity of opinion between the two groups on the relative salary values of the options, though the consultants consistently priced these higher than the managers. PMID:8086915

40 CFR 35.937-9 - Required solicitation and subagreement provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

...; (2) The time for performance and completion of the contract work, including where appropriate, dates for completion of significant project tasks; (3) Personnel and facilities necessary to accomplish the... for later tasks or steps at the time of contract execution, the contract should not include the...

26 CFR 1.402A-1 - Designated Roth Accounts.

Code of Federal Regulations, 2011 CFR

2011-04-01

... relationship between the accounting for designated Roth contributions as investment in the contract for... includible in gross income as an amount allocable to investment in the contract is determined under section... contract and the portion not includible in gross income as an amount allocable to investment in the...

48 CFR 538.7002 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., regional, or tribal government, or any instrumentality thereof (including any local educational agency or... contracts containing information technology SINs, and Schedule 84 contracts. A listing of the participating... Consolidated Schedule contracts containing information technology SINs, and Schedule 84 contracts, is available...

78 FR 72572 - Operational Contract Support

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-03

... 0790-AI48 Operational Contract Support AGENCY: Department of Defense (DoD). ACTION: Final rule. SUMMARY: This rule establishes policy, assigns responsibilities, and provides procedures for operational contract support (OCS), including OCS program management, contract support integration, and integration of...

48 CFR 232.070 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... DoD contract financing, including DoD contract financing policies and important related procedures... operations. Refer specific cases involving financing policy or important procedural issues to OUSD(AT&L)DPAP... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING 232.070 Responsibilities. (a) The...

29 CFR 4.120 - Contracts for public utility services.

Code of Federal Regulations, 2010 CFR

2010-07-01

... McNamara-O'Hara Service Contract Act Specific Exclusions § 4.120 Contracts for public utility services. The Act, in paragraph (5) of section 7, exempts from its provisions “any contract for public utility... regulation, are not exempt from the Act. Among the contracts included in the exemption would be those between...

The Tie that Binds: The Role and Evolution of Contracts in Interlibrary Cooperation.

ERIC Educational Resources Information Center

Scrimgeour, Andrew D.; Potter, Susan

This paper examines the importance of contracts in formalizing agreements between libraries to provide services to off-campus students and describes the development of one such contract. Topics addressed include: (1) the value of contracts in clarifying responsibilities and elevating contracted services in the hierarchy of institutional…

An Exploratory Study of Alpha Contracting: Antecedents, Processes, Issues, Success Factors and Consequences

DTIC Science & Technology

2009-09-01

ABSTRACT (maximum 200 words) Alpha contracting is a collaborative effort between a buyer and supplier during contract formation to maximize efficiency...experienced Alpha contracting teams, to include contracting officers, DCAA, DCMA, end users/ customers , program managers and acquisition directors to better...PROCESSES, ISSUES, SUCCESS FACTORS AND CONSEQUENCES ABSTRACT Alpha contracting is a collaborative effort between a buyer and supplier

77 FR 12888 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

... instant contract is functionally equivalent to the IBRS 3 baseline contract originally filed in Docket Nos... product, also authorized functionally equivalent agreements to be included within the product, provided... Service Filing of a Functionally Equivalent International Business Reply Service Competitive Contract 3...

Contracting out of clinical services in Zimbabwe.

PubMed

McPake, B; Hongoro, C

1995-07-01

Contracting is increasingly recommended to developing countries as a way of improving the efficiency of the health sector. However, empirical evidence regarding its effectiveness in this respect is almost completely absent. In Zimbabwe, a long standing contract exists between the Ministry of Health and Wankie Colliery to provide clinical services in the Colliery's 400 bed hospital. This paper details a study of the Zimbabweans' experience with the contract. Its success is assessed using comparisons with a neighbouring government hospital of the price of services (vs the cost in the government hospital); the situation of hospital workers; and the quality of services delivered. The Colliery has established a monopoly position for hospital services in the district. However, it appears to offer services of at least as good quality at prices which are lower than the unit costs of the government hospital when capital costs are included. Nevertheless, the contract cannot be considered a success due to the failure to contain its total cost. Approximately 70% of provincial non-salary recurrent expenditure is consumed by the contract while only a minority of the province's population have access to the Colliery hospital. Screening patients, both with respect to their ability to pay and to their need for secondary level services does not take place with the result that utilization levels are not controlled. The study highlights a number of important issues affecting contracting in developing country setting: First, contracted institutions attain powerful bargaining positions if there are no viable competitors and the government does not itself retain capacity to offer an alternative service. Second, specific skills are needed for the management of contracts at all levels. If the process of contract development responds to a crisis driven agenda resulting from civil service retrenchment and public expenditure cuts, it is unlikely that adequate consideration will be given to the development of such skills and the retention of key personnel. If such details are neglected, otherwise feasible efficiency gains will prove elusive.

Part-Time Faculty in 2-Year Colleges.

ERIC Educational Resources Information Center

National Center for the Study of Collective Bargaining in Higher Education Newsletter, 1977

1977-01-01

Recognition clauses of negotiated faculty contracts from 139 two-year colleges were analyzed to determine the extent to which part-time faculty are included in the bargaining unit, and to examine contract references to part-time faculty. Approximately one-half (71) of the contracts did not include part-time faculty as members. Exclusion was either…

29 CFR 471.2 - What employee notice clause must be included in Government contracts?

Code of Federal Regulations, 2011 CFR

2011-07-01

... to Government contracts, considered as a group. (e) Obtaining a poster with the employee notice. A poster with the required employee notice, including a poster with the employee notice translated into... Federal Contract Compliance Programs. A copy of the poster in English and in languages other than English...

29 CFR 471.2 - What employee notice clause must be included in Government contracts?

Code of Federal Regulations, 2013 CFR

2013-07-01

... to Government contracts, considered as a group. (e) Obtaining a poster with the employee notice. A poster with the required employee notice, including a poster with the employee notice translated into... Federal Contract Compliance Programs. A copy of the poster in English and in languages other than English...

29 CFR 471.2 - What employee notice clause must be included in Government contracts?

Code of Federal Regulations, 2012 CFR

2012-07-01

... to Government contracts, considered as a group. (e) Obtaining a poster with the employee notice. A poster with the required employee notice, including a poster with the employee notice translated into... Federal Contract Compliance Programs. A copy of the poster in English and in languages other than English...

29 CFR 471.2 - What employee notice clause must be included in Government contracts?

Code of Federal Regulations, 2014 CFR

2014-07-01

... to Government contracts, considered as a group. (e) Obtaining a poster with the employee notice. A poster with the required employee notice, including a poster with the employee notice translated into... Federal Contract Compliance Programs. A copy of the poster in English and in languages other than English...

NASA Awards Chandra X-Ray Observatory Follow-On Contract

NASA Astrophysics Data System (ADS)

2003-08-01

NASA has awarded a contract to the Smithsonian Astrophysical Observatory in Cambridge, Mass., to provide science and operational support for the Chandra X-ray Observatory, one of the world's most powerful tools to better understand the structure and evolution of the universe. The contract will have a period of performance from August 31, 2003, through July 31, 2010, with an estimated value of 373 million. It is a follow-on contract to the existing contract with Smithsonian Astrophysical Observatory that has provided science and operations support to the Observatory since its launch in July 1999. At launch the intended mission life was five years. As a result of Chandra's success, NASA extended the mission from five to 10 years. The value of the original contract was 289 million. The follow-on contract with the Smithsonian Astrophysical Observatory will continue through the 10-year mission. The contract type is cost reimbursement with no fee. The contract covers mission operations and data analysis, which includes the observatory operations, science data processing and the general and guaranteed time observer (astronomer) support. The observatory operations tasks include monitoring the health and status of the observatory and developing and up linking the observation sequences during Chandra's communication coverage periods. The science data processing tasks include the competitive selection, planning, and coordination of science observations with the general observers and processing and delivery of the resulting scientific data. There are approximately 200 to 250 observing proposals selected annually out of about 800 submitted, with a total amount of observing time of about 20 million seconds. Chandra has exceeded expectations of scientists, giving them unique insight into phenomena light years away, such as exotic celestial objects, matter falling into black holes, and stellar explosions. X-ray astronomy can only be performed from space because Earth's atmosphere blocks X-rays from reaching the surface. The Chandra Observatory travels one-third of the way to the moon during its orbit around the Earth every 64 hours. At its highest point, Chandra's highly elliptical, or egg- shaped, orbit is 200 times higher than that of its visible- light-gathering sister, the Hubble Space Telescope. NASA's Marshall Space Flight Center, Huntsville, Ala., manages the Chandra program for the Office of Space Science, NASA Headquarters, Washington. Northrop Grumman of Redondo Beach, Calif., formerly TRW, Inc., was the prime development contractor for the observatory. The Smithsonian Astrophysical Observatory controls science and flight operations from the Chandra X-ray Center in Cambridge, Mass. For information about NASA on the Internet, visit: http://www.nasa.gov For information about the Chandra X-ray Observatory on the Internet, visit: http://chandra.harvard.edu and http://chandra.nasa.gov

48 CFR 28.306 - Insurance under fixed-price contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... requirements under fixed-price contracts. Examples of such circumstances include the following: (1) The...-price contracts. 28.306 Section 28.306 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Insurance 28.306 Insurance under fixed-price...

48 CFR 2009.570-5 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... COMPETITION AND ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Organizational Conflicts of Interest 2009.570-5 Contract clauses. (a) General contract clause. All contracts and simplified acquisitions of the types set forth in 2009.570-4(b) must include the clause entitled, “Contractor Organizational Conflicts of...

48 CFR 816.102 - Policies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Policies. 816.102 Section... CONTRACT TYPES TYPES OF CONTRACTS Selecting Contract Types 816.102 Policies. (a) Contracting officers must obtain technical review of solicitations that include a clause that provides for economic price...

48 CFR 315.7000 - Section 508 accessibility standards.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Acquisition of Electronic Information Technology 315.7000 Section 508 accessibility standards. EIT products and services, including EIT...

48 CFR 31.205-8 - Contributions or donations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Commercial Organizations 31.205-8 Contributions or donations. Contributions or donations, including cash, property and...

Teaching Activities for the Construction of a Precursor Model in 5- to 6-Year-Old Children's Thinking: The Case of Thermal Expansion and Contraction of Metals

ERIC Educational Resources Information Center

Ravanis, Konstantinos; Papandreou, Maria; Kampeza, Maria; Vellopoulou, Angeliki

2013-01-01

This article presents the results of empirical research on the construction of a precursor model of the phenomenon of thermal expansion and contraction of metals in preschool children's thinking, which is compatible with the model used in science education. The research included 87 children aged 5-6. It was conducted at four stages, during…

Communication Lower Bounds and Optimal Algorithms for Programs that Reference Arrays - Part 1

DTIC Science & Technology

2013-05-14

include tensor contractions, the direct N-body algorithm, and database join. 1This indicates that this is the first of 5 times that matrix multiplication...and database join. Section 8 summarizes our results, and outlines the contents of Part 2 of this paper. Part 2 will discuss how to compute lower...contractions, the direct N–body algo- rithm, database join, and computing matrix powers Ak. 2 Geometric Model We begin by reviewing the geometric

A Measurement of AFIT Contracting and Acquisition Management Program Usefulness as Perceived by Graduates and Their Supervisors.

DTIC Science & Technology

1982-09-01

21 functions. The legal category covers the business, commer- cial and contract law fields, including patents and royalties, technical data, claims...Course Rankings Question # Subject Area Median Rank 55,56,59 Contract Management Theory 7.0 1 53,54 Contract Law 6.5 2 So Contracting & Acquis. Mgt...respondents ranked Contract Management Theory as the most useful course among all courses in the AFIT CAM curriculum. Graduates ranked Contract Law as

Employee contract issues for dermatologists.

PubMed

Brown, Christopher E; Indest, George F

2013-12-01

Employees and employers routinely face negotiating and preparing physician employment contracts. It is important for both sides to know and understand the basic information on what a comprehensive employment contract for a dermatologist should contain. There are various employment contract provisions from both the employee's perspective and the employer's perspective that must be considered when preparing physician employment contracts. This article provides basic advice and recommendations on requirements that should be included in such contracts. It suggests legal pitfalls that can be avoided through various contract clauses.

A review of mixing and propulsion of chyme in the small intestine: fresh insights from new methods.

PubMed

Lentle, R G; de Loubens, C

2015-05-01

The small intestine is a convoluted flexible tube of inconstant form and capacity through which chyme is propelled and mixed by varying patterns of contraction. These inconstancies have prevented quantitative comparisons of the manner in which contractile activity engenders mixing of contained chyme. Recent quantitative work based on spatiotemporal mapping of intestinal contractions, macro- and micro-rheology, particle image velocimetry and real-time modelling has provided new insights into this process. Evidence indicates that the speeds and patterns of the various types of small intestinal contraction are insufficient to secure optimal mixing and enzymatic digestion over a minimal length of intestine. Hence particulate substrates and soluble nutrients become dispersed along the length of the lumen. Mixing within the lumen is not turbulent but results from localised folding and kneading of the contents by contractions but is augmented by the inconstant spatial disposition of the contractions and their component contractile processes. The latter include inconstancies in the sites of commencement and the directions of propagation of contraction in component groups of smooth muscle cells and in the coordination of the radial and circular components of smooth muscle contraction. Evidence suggests there is ongoing augmentation of mixing at the periphery of the lumen, during both the post-prandial and inter-meal periods, to promote flow around and between adjacent villi. This results largely from folding of the relatively inelastic mucosa during repeated radial and longitudinal muscular contraction, causing chyme to be displaced by periodic crowding and separation of the tips of the relatively rigid villi. Further, micro-rheological studies indicate that such peripheral mixing may extend to the apices of enterocytes owing to discontinuities in the mobile mucus layer that covers the ileal mucosa.

Free-standing oxide superconducting articles

DOEpatents

Wu, Xin D.; Muenchausen, Ross E.

1993-01-01

A substrate-free, free-standing epitaxially oriented superconductive film including a layer of a template material and a layer of a ceramic superconducting material is provided together with a method of making such a substrate-free ceramic superconductive film by coating an etchable material with a template layer, coating the template layer with a layer of a ceramic superconductive material, coating the layer of ceramic superconductive material with a protective material, removing the etchable material by an appropriate means so that the etchable material is separated from a composite structure including the template lay This invention is the result of a contract with the Department of Energy (Contract No. W-7405-ENG-36).

24 CFR 241.605 - Contract requirements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems, and Individual Utility... plus contract. Either form of contract shall include the cost of the energy conserving improvements...

24 CFR 241.605 - Contract requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems, and Individual Utility... plus contract. Either form of contract shall include the cost of the energy conserving improvements...

24 CFR 241.605 - Contract requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems, and Individual Utility... plus contract. Either form of contract shall include the cost of the energy conserving improvements...

24 CFR 241.605 - Contract requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems, and Individual Utility... plus contract. Either form of contract shall include the cost of the energy conserving improvements...

24 CFR 241.605 - Contract requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Purchase and Installation of Energy Conserving Improvements, Solar Energy Systems, and Individual Utility... plus contract. Either form of contract shall include the cost of the energy conserving improvements...

SRB Environment Evaluation and Analysis. Volume 3: ASRB Plume Induced Environments

NASA Technical Reports Server (NTRS)

Bender, R. L.; Brown, J. R.; Reardon, J. E.; Everson, J.; Coons, L. W.; Stuckey, C. I.; Fulton, M. S.

1991-01-01

Contract NAS8-37891 was expanded in late 1989 to initiate analysis of Shuttle plume induced environments as a result of the substitution of the Advanced Solid Rocket Booster (ASRB) for the Redesigned Solid Rocket Booster (RSRB). To support this analysis, REMTECH became involved in subscale and full-scale solid rocket motor test programs which further expanded the scope of work. Later contract modifications included additional tasks to produce initial design cycle environments and to specify development flight instrumentation. Volume 3 of the final report describes these analyses and contains a summary of reports resulting from various studies.

48 CFR 15.404-3 - Subcontract pricing considerations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.404-3 Subcontract..., including subcontractor's certified cost or pricing data. (b) The prime contractor or subcontractor shall... paragraph (c) of this subsection, submit subcontractor certified cost or pricing data to the Government as...

48 CFR 15.404-3 - Subcontract pricing considerations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.404-3 Subcontract..., including subcontractor's certified cost or pricing data. (b) The prime contractor or subcontractor shall... paragraph (c) of this subsection, submit subcontractor certified cost or pricing data to the Government as...

48 CFR 15.404-3 - Subcontract pricing considerations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.404-3 Subcontract..., including subcontractor's certified cost or pricing data. (b) The prime contractor or subcontractor shall... paragraph (c) of this subsection, submit subcontractor certified cost or pricing data to the Government as...

48 CFR 915.404-4-72 - Special considerations for cost-plus-award-fee contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... management and operating contracts or other contracts as determined by the Senior Procurement Executive, including those using the Construction, Construction Management, or Special Equipment Purchases/Subcontract... for construction and construction management contracts). However, the base amount should not normally...

48 CFR 915.404-4-72 - Special considerations for cost-plus-award-fee contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... management and operating contracts or other contracts as determined by the Senior Procurement Executive, including those using the Construction, Construction Management, or Special Equipment Purchases/Subcontract... for construction and construction management contracts). However, the base amount should not normally...

48 CFR 915.404-4-72 - Special considerations for cost-plus-award-fee contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... management and operating contracts or other contracts as determined by the Senior Procurement Executive, including those using the Construction, Construction Management, or Special Equipment Purchases/Subcontract... for construction and construction management contracts). However, the base amount should not normally...

48 CFR 915.404-4-72 - Special considerations for cost-plus-award-fee contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... management and operating contracts or other contracts as determined by the Senior Procurement Executive, including those using the Construction, Construction Management, or Special Equipment Purchases/Subcontract... for construction and construction management contracts). However, the base amount should not normally...

48 CFR 31.103 - Contracts with commercial organizations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contracts with commercial... with commercial organizations. This category includes all contracts and contract modifications for... modifications with commercial organizations whenever cost analysis is performed as required by 15.404-1(c). (b...

48 CFR 12.210 - Contract financing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contract financing. 12.210... financing. Customary market practice for some commercial items may include buyer contract financing. The contracting officer may offer Government financing in accordance with the policies and procedures in part 32. ...

36 CFR 51.81 - May the Director include “special account” provisions in concession contracts?

Code of Federal Regulations, 2010 CFR

2010-07-01

... concessioner in its operations. Repair and maintenance reserve funds may not be expended to construct real... provisions may not be included in concession contracts in lieu of a franchise fee, and funds from the... concessioner by the Director for use in its operations. (c) A concession contract must require the concessioner...

78 FR 30948 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing of Advance...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-23

... Options on Interest Rate Futures Contracts With Maturities Not Longer Than Two Years in the One- Pot Cross... allow FICC to include options on interest rate futures contracts with maturities not longer than two...) The purpose of the advance notice is to include options on interest rate futures contracts with...

48 CFR 252.225-7033 - Waiver of United Kingdom levies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... waiver of levies included in the price of this contract, the U.S. Government reserves the right to reduce the contract price by the amount of the levy waived plus associated indirect costs and profit or fee... attempt to obtain a waiver of any commercial exploitation levies included in the price of this contract...

14 CFR 259.6 - Notice and contract of carriage.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Web site shall post its Contract of Carriage on its Web site in easily accessible form, including all... Lengthy Tarmac Delays shall, if it has a Web site but does not include such Contingency Plan for Lengthy Tarmac Delays in its Contract of Carriage, post its Contingency Plan for Lengthy Tarmac Delays on its Web...

14 CFR 259.6 - Notice and Contract of Carriage.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Web site shall post its Contract of Carriage on its Web site in easily accessible form, including all... Lengthy Tarmac Delays shall, if it has a Web site but does not include such Contingency Plan for Lengthy Tarmac Delays in its Contract of Carriage, post its Contingency Plan for Lengthy Tarmac Delays on its Web...

36 CFR 51.76 - May the Director include in a concession contract or otherwise grant a concessioner a...

Code of Federal Regulations, 2010 CFR

2010-07-01

... concession contract or otherwise grant a concessioner a preferential right to provide new or additional... include in a concession contract or otherwise grant a concessioner a preferential right to provide new or... grant a concessioner a preferential right to provide new or additional visitor services under the terms...

Violence in contract work among female sex workers in Andhra Pradesh, India.

PubMed

George, Annie; Sabarwal, Shagun; Martin, P

2011-12-01

Female sex workers (FSWs) are vulnerable to physical and sexual violence at work. This article examines the prevalence of recent physical and sexual violence victimization and associations of type of sex work among a large sample of young FSWs. We used data from a cross-sectional survey on sex trafficking and sex work in southern India that included 1138 FSWs aged 18-25 years residing in 3 districts of Andhra Pradesh state. The independent variable was organization of sex work. FSWs on contract at sex work establishments outside their home district were classified as contract workers, as compared with women who worked autonomously within their home district. Using logistic regression models adjusted for sociodemographic factors, we assessed the relation between contract/ non-contract sex work and various forms of violence experienced by FSWs. Results indicate a high prevalence of work-related physical and sexual violence; 50% FSWs reported physical violence, and 77% reported sexual violence. FSWs performing contract work were at increased risk of physical and sexual violence at work, compared with women engaged in sex work in their home districts. The findings that contract work outside the home district increases the vulnerabilities faced by FSWs in India suggest that violence and disease prevention services aimed at FSWs would be more effective if organization of sex work--as contract or noncontract--is taken into account.

Energy Lessons by Contract.

ERIC Educational Resources Information Center

Wagganer, John W.

1981-01-01

An elementary activity based energy education unit which utilizes student contracts is described. Examples of the preparation involved, student involvement entailed, and examples of contracts and grading criteria are included. (DS)

An Analysis of Contracting Officer Technical Representative Training Requirements.

DTIC Science & Technology

1982-06-01

AI and contract law . On the basis of the perceived need to eliminate superflu- ous material from the training of CA contract representatives and...Cost and pricing principles 3. Basic contract law 4. Types of contracts S. Definition of important terms 6. Understanding the terms and conditions--how...digesting and/or deletions to coincide with the learning objectives developed in Chapter III include: 1. Federal Acquisition Policy 2. Contract Law 3

42 CFR 137.239 - If the withdrawing Indian Tribe elects to operate PSFAs carried out under a compact or funding...

Code of Federal Regulations, 2013 CFR

2013-10-01

..., is the resulting contract considered a mature contract under section 4(h) of the Act [25 U.S.C. 450b... agreement under Title V through a contract under Title I, is the resulting contract considered a mature... Title I, the resulting contract is considered a mature contract under section 4(h) of the Act [25 U.S.C...

42 CFR 137.239 - If the withdrawing Indian Tribe elects to operate PSFAs carried out under a compact or funding...

Code of Federal Regulations, 2012 CFR

2012-10-01

..., is the resulting contract considered a mature contract under section 4(h) of the Act [25 U.S.C. 450b... agreement under Title V through a contract under Title I, is the resulting contract considered a mature... Title I, the resulting contract is considered a mature contract under section 4(h) of the Act [25 U.S.C...

42 CFR 137.239 - If the withdrawing Indian Tribe elects to operate PSFAs carried out under a compact or funding...

Code of Federal Regulations, 2014 CFR

2014-10-01

..., is the resulting contract considered a mature contract under section 4(h) of the Act [25 U.S.C. 450b... agreement under Title V through a contract under Title I, is the resulting contract considered a mature... Title I, the resulting contract is considered a mature contract under section 4(h) of the Act [25 U.S.C...

48 CFR 7.101 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... that involve redesign of systems or subsystems. Life-cycle cost means the total cost to the Government... included, at the most appropriate time in the acquisition cycle, in solicitations and resulting contracts...

48 CFR 7.101 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... that involve redesign of systems or subsystems. Life-cycle cost means the total cost to the Government... included, at the most appropriate time in the acquisition cycle, in solicitations and resulting contracts...

48 CFR 7.101 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... that involve redesign of systems or subsystems. Life-cycle cost means the total cost to the Government... included, at the most appropriate time in the acquisition cycle, in solicitations and resulting contracts...

7 CFR 1780.75 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE (CONTINUED) WATER AND WASTE LOANS AND GRANTS Planning, Designing, Bidding, Contracting... including the manner by which it will be effected and the basis for settlement. In addition, such contracts...

48 CFR 15.401 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.401 Definitions. As used in this... used in 15.407-2) also includes a transfer of commercial items between divisions, subsidiaries, or...

29 CFR 4.114 - Subcontracts.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Secretary of Labor LABOR STANDARDS FOR FEDERAL SERVICE CONTRACTS Application of the McNamara-O'Hara Service Contract Act Covered Contracts Generally § 4.114 Subcontracts. (a) “Contractor” as including “subcontractor... contractor undertakes a contract subject to the Act, the contractor agrees to assume the obligation that the...

49 CFR 19.48 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... remedies in instances in which a contractor violates or breaches the contract terms, and provide for such... 49 Transportation 1 2010-10-01 2010-10-01 false Contract provisions. 19.48 Section 19.48... Requirements Procurement Standards § 19.48 Contract provisions. The recipient shall include, in addition to...

48 CFR 1632.772 - Contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Contract clause. 1632.772 Section 1632.772 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT FEDERAL EMPLOYEES... Funding 1632.772 Contract clause. The clause at 1652.232-72 shall be included in all contracts that are...

48 CFR 49.105 - Duties of termination contracting officer after issuance of notice of termination.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.105 Duties of termination contracting officer after issuance of notice of termination. (a... principles relating to the settlement of any settlement proposal, including obligations of the contractor...

29 CFR 4.163 - Section 4(c) of the Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... their support contracts. Thus, specific contract requirements from one contract may be broken out and... substantially the same job classifications, the predecessor contract which covers the greater portion of the... bargaining agreement. However, failure to include in the wage determination any job classification, wage rate...

29 CFR 4.163 - Section 4(c) of the Act.

Code of Federal Regulations, 2012 CFR

2012-07-01

... their support contracts. Thus, specific contract requirements from one contract may be broken out and... substantially the same job classifications, the predecessor contract which covers the greater portion of the... bargaining agreement. However, failure to include in the wage determination any job classification, wage rate...

29 CFR 4.163 - Section 4(c) of the Act.

Code of Federal Regulations, 2014 CFR

2014-07-01

... their support contracts. Thus, specific contract requirements from one contract may be broken out and... substantially the same job classifications, the predecessor contract which covers the greater portion of the... bargaining agreement. However, failure to include in the wage determination any job classification, wage rate...

29 CFR 4.163 - Section 4(c) of the Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... their support contracts. Thus, specific contract requirements from one contract may be broken out and... substantially the same job classifications, the predecessor contract which covers the greater portion of the... bargaining agreement. However, failure to include in the wage determination any job classification, wage rate...

The origins of length contraction: I. The FitzGerald-Lorentz deformation hypothesis

NASA Astrophysics Data System (ADS)

Brown, Harvey R.

2001-10-01

"Can there be some point in the theory of Mr. Michelson's experiment which has yet been overlooked?" H. A. Lorentz, letter to Lord Rayleigh, August 1892. One of the widespread confusions concerning the history of the 1887 Michelson-Morley experiment has to do with the initial explanation of this celebrated null result due independently to FitzGerald and Lorentz. In neither case was a strict, longitudinal length contraction hypothesis invoked, as is commonly supposed. Lorentz postulated, particularly in 1895, any one of a certain family of possible deformation effects for rigid bodies in motion, including purely transverse alteration, and expansion as well as contraction; FitzGerald may well have had the same family in mind. A careful analysis of the Michelson-Morley experiment (which reveals a number of serious inadequacies in many textbook treatments) indeed shows that strict contraction is not required.

Selective heart rate variability analysis to account for uterine activity during labor and improve classification of fetal distress.

PubMed

Warmerdam, G J J; Vullings, R; Van Laar, J O E H; Van der Hout-Van der Jagt, M B; Bergmans, J W M; Schmitt, L; Oei, S G

2016-08-01

Cardiotocography (CTG) is currently the most often used technique for detection of fetal distress. Unfortunately, CTG has a poor specificity. Recent studies suggest that, in addition to CTG, information on fetal distress can be obtained from analysis of fetal heart rate variability (HRV). However, uterine contractions can strongly influence fetal HRV. The aim of this study is therefore to investigate whether HRV analysis for detection of fetal distress can be improved by distinguishing contractions from rest periods. Our results from feature selection indicate that HRV features calculated separately during contractions or during rest periods are more informative on fetal distress than HRV features that are calculated over the entire fetal heart rate. Furthermore, classification performance improved from a geometric mean of 69.0% to 79.6% when including the contraction-dependent HRV features, in addition to HRV features calculated over the entire fetal heart rate.

The effectiveness of contingency management in the treatment of patients with anorexia nervosa: A systematic review.

PubMed

Ziser, Katrin; Resmark, Gaby; Giel, Katrin Elisabeth; Becker, Sandra; Stuber, Felicitas; Zipfel, Stephan; Junne, Florian

2018-03-26

Contingency management in stipulating weight gain is routinely used in the treatment of anorexia nervosa, however, empirical investigations concerning its effectiveness have been scarce. This systematic review was conducted according to the PRISMA statement. Of N = 973 hits, 42 full-texts were included in the qualitative synthesis (11 theoretical texts, 19 case reports, 12 descriptive, cohort, and controlled trials). A central topic in the included publications concerns the enhancement of patients' autonomy through participation in the contingency management process. This heightened autonomy is achieved by using contingency contracts. Positive short-term effects on weight gain were shown, whereas follow-up results were heterogeneous. Although contingency contracts are widely used in clinical practice, our systematic review shows that empirical evidence on underlying mechanisms and efficacy is still scarce. Using an explicit treatment contract can enhance patients' motivation, compliance, and autonomy. Clinical practice should see further development including innovative motivation enhancing and conflict dissolving techniques in addressing the pronounced ambivalence often shown by patients with anorexia nervosa. Copyright © 2018 John Wiley & Sons, Ltd and Eating Disorders Association.

Perceived barriers to utilizing maternal and neonatal health services in contracted-out versus government-managed health facilities in the rural districts of Pakistan.

PubMed

Riaz, Atif; Zaidi, Shehla; Khowaja, Asif Raza

2015-03-06

A number of developing countries have contracted out public health facilities to the Non-Government Organizations (NGOs) in order to improve service utilization. However, there is a paucity of in-depth qualitative information on barriers to access services as a result of contracting from service users' perspective. The objective of this study was to explore perceived barriers to utilizing Maternal and Neonatal Health (MNH) services, in health facilities contracted out by government to NGO for service provision versus in those which are managed by government (non-contracted). A community-based qualitative exploratory study was conducted between April to September 2012 at two contracted-out and four matched non-contracted primary healthcare facilities in Thatta and Chitral, rural districts of Pakistan. Using semi-structured guide, the data were collected through thirty-six Focus Group Discussions (FGDs) conducted with mothers and their spouses in the catchment areas of selected facilities. Thematic analysis was performed using NVivo version 10.0 in which themes and sub-themes emerged. Key barriers reported in contracted sites included physical distance, user charges and familial influences. Whereas, poor functionality of health centres was the main barrier for non-contracted sites with other issues being comparatively less salient. Decision-making patterns for participants of both catchments were largely similar. Spouses and mother-in-laws particularly influenced the decision to utilize health facilities. Contracting out of health facility reduces supply side barriers to MNH services for the community served but distance, user charges and low awareness remain significant barriers. Contracting needs to be accompanied by measures for transportation in remote settings, oversight on user fee charges by contractor, and strong community-based behavior change strategies. © 2015 by Kerman University of Medical Sciences.

Retailer Stackelberg game in a supply chain with pricing and service decisions and simple price discount contract.

PubMed

Sadjadi, Seyed Jafar; Asadi, Hashem; Sadeghian, Ramin; Sahebi, Hadi

2018-01-01

This paper studies the Retailer Stackelberg game in a supply chain consisting of two manufacturers and one retailer where they compete simultaneously under three factors including price, service and simple price discount contract. It is assumed that the second manufacturer provides service directly to his customers, and the retailer provides service for the first product's customers, while the retailer buys the first product under price discount from the first manufacturer. The analysis of the optimal equilibrium solutions and the results of the numerical examples show that if a manufacturer chooses the appropriate range of discount rate, he will gain more profit than when there is no discount given to the retailer. This situation can be considered as an effective tool for the coordination of the first manufacturer and the retailer to offer discount by manufacturer and to provide the service by the retailer. We obtain equilibrium solution of Retailer Stackelberg game and analyze the numerical examples under two cases: a) the manufacturers sell their products to the retailer without price discount contract. b) The first manufacturer sells his products to the retailer with the simple price discount contract. The preliminary results show that the service and the price discount contract can improve the performance of supply chain.

Retailer Stackelberg game in a supply chain with pricing and service decisions and simple price discount contract

PubMed Central

Sadjadi, Seyed Jafar; Sadeghian, Ramin; Sahebi, Hadi

2018-01-01

This paper studies the Retailer Stackelberg game in a supply chain consisting of two manufacturers and one retailer where they compete simultaneously under three factors including price, service and simple price discount contract. It is assumed that the second manufacturer provides service directly to his customers, and the retailer provides service for the first product’s customers, while the retailer buys the first product under price discount from the first manufacturer. The analysis of the optimal equilibrium solutions and the results of the numerical examples show that if a manufacturer chooses the appropriate range of discount rate, he will gain more profit than when there is no discount given to the retailer. This situation can be considered as an effective tool for the coordination of the first manufacturer and the retailer to offer discount by manufacturer and to provide the service by the retailer. We obtain equilibrium solution of Retailer Stackelberg game and analyze the numerical examples under two cases: a) the manufacturers sell their products to the retailer without price discount contract. b) The first manufacturer sells his products to the retailer with the simple price discount contract. The preliminary results show that the service and the price discount contract can improve the performance of supply chain. PMID:29649315

29 CFR 4.107 - Federal contracts.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., such as Federal Reserve Banks, are included among those subject to the general coverage of the Act.... Gen. Ops. ___ (September 26, 1978).) Contracts with the Federal Government and contracts entered into...

29 CFR 4.107 - Federal contracts.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., such as Federal Reserve Banks, are included among those subject to the general coverage of the Act.... Gen. Ops. ___ (September 26, 1978).) Contracts with the Federal Government and contracts entered into...

29 CFR 4.107 - Federal contracts.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., such as Federal Reserve Banks, are included among those subject to the general coverage of the Act.... Gen. Ops. ___ (September 26, 1978).) Contracts with the Federal Government and contracts entered into...

Effect of endothelin-1 on the serotonin-induced contraction of smooth muscle in the guinea pig trachea.

PubMed

Yoshida, M; Aizawa, H; Hara, N

1999-01-01

Endothelin (ET), a potent constrictor of smooth muscle including that of the airways, may contribute to the development of airway hyperresponsiveness. To investigate the role of ET-1 on the airway smooth muscle, we examined the effects of ET-1 on the serotonin-induced contraction of guinea pig tracheal smooth muscle. The changes in isometric tension evoked by serotonin were measured before and after the application of a subthreshold dose (a dose which did not induce smooth muscle contraction by itself) of ET-1. Serotonin caused smooth muscle contraction in a dose-dependent manner. The subthreshold doses of ET-1 (1 pM) and sarafotoxin 6c (1 pM), a selective ETB receptor agonist, were found to potentiate significantly the contraction induced by serotonin. A potentiating effect of ET-1 was not altered by indomethacin or calphostin C, a protein kinase C inhibitor. These results suggest that a subthreshold concentration of ET-1 can potentiate serotonin-induced contraction of smooth muscle through the activation of ETB receptor, while in contrast cyclooxygenase and protein kinase C were found not to be involved in this mechanism.

Protecting the Environment Through Public Procurement Law - The Case of Poland

NASA Astrophysics Data System (ADS)

Kozik, Renata; Karasińska-Jaśkowiec, Izabela

2016-10-01

The article presents the results of studies whose aim was to analyse public procurement procedures in the context of environmental protection, especially wastewater infrastructure, performed in the selected Polish municipalities. The selection criterions were the time of public procurement procedure - from 2009 until 2015 and that the contract was cofinanced by the European Union funds. The contracting authorities responsible for awarding specific contracts, were asked series of detailed questions about the environmental criteria and requirements contained in the tender documents for the construction contracts related to the wastewater infrastructure. The aim of the detailed study was to determine whether the actions taken by the contracting authorities in a tender procedure for the construction or operation of wastewater infrastructure include environmental issues. Authors examine also the applicable public procurement law regulation in Poland and Europe in the context of sustainable development and environmental protection. The study of public procurement law was to check whether the law regulation fully takes into account the environmental aspects of the planned investments. On this basis, conclusions have been made that laws are consistent and do not constitute an obstacle to awarding a contract positively affecting the environment.

The INCENTIVE protocol: an evaluation of the organisation and delivery of NHS dental healthcare to patients—innovation in the commissioning of primary dental care service delivery and organisation in the UK

PubMed Central

Pavitt, Sue H; Baxter, Paul D; Brunton, Paul A; Douglas, Gail; Edlin, Richard; Gibson, Barry J; Godson, Jenny; Hall, Melanie; Porritt, Jenny; Robinson, Peter G; Vinall, Karen; Hulme, Claire

2014-01-01

Introduction In England, in 2006, new dental contracts devolved commissioning of dental services locally to Primary Care Trusts to meet the needs of their local population. The new national General Dental Services contracts (nGDS) were based on payment for Units of Dental Activity (UDAs) awarded in three treatment bands based on complexity of care. Recently, contract currency in UK dentistry is evolving from UDAs based on volume and case complexity towards ‘blended contracts’ that include incentives linked with key performance indicators such as quality and improved health outcome. Overall, evidence of the effectiveness of incentive-driven contracting of health providers is still emerging. The INCENTIVE Study aims to evaluate a blended contract model (incentive-driven) compared to traditional nGDS contracts on dental service delivery in practices in West Yorkshire, England. Methods and analysis The INCENTIVE model uses a mixed methods approach to comprehensively evaluate a new incentive-driven model of NHS dental service delivery. The study includes 6 dental surgeries located across three newly commissioned dental practices (blended contract) and three existing traditional practices (nGDS contracts). The newly commissioned practices have been matched to traditional practices by deprivation index, age profile, ethnicity, size of practice and taking on new patients. The study consists of three interlinked work packages: a qualitative study to explore stakeholder perspectives of the new service delivery model; an effectiveness study to assess the INCENTIVE model in reducing the risk of and amount of dental disease and enhance oral health-related quality of life in patients; and an economic study to assess cost-effectiveness of the INCENTIVE model in relation to clinical status and oral health-related quality of life. Ethics and dissemination The study has been approved by NRES Committee London, Bromley. The results of this study will be disseminated at national and international conferences and in international journals. PMID:25231492

48 CFR 17.202 - Use of options.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Use of options. 17.202... AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 17.202 Use of options. (a) Subject to the..., the contracting officer may include options in contracts when it is in the Government's interest. When...

36 CFR 1210.48 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... instances in which a contractor violates or breaches the contract terms, and provide for such remedial... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Contract provisions. 1210.48... § 1210.48 Contract provisions. The recipient shall include, in addition to provisions to define a sound...

22 CFR 518.48 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... remedies in instances in which a contractor violates or breaches the contract terms, and provide for such... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Contract provisions. 518.48 Section 518.48... Requirements Procurement Standards § 518.48 Contract provisions. The recipient shall include, in addition to...

7 CFR 3019.48 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... instances in which a contractor violates or breaches the contract terms, and provide for such remedial... 7 Agriculture 15 2010-01-01 2010-01-01 false Contract provisions. 3019.48 Section 3019.48... Standards § 3019.48 Contract provisions. The recipient shall include, in addition to provisions to define a...

7 CFR 550.50 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... legal remedies in instances in which a contractor violates or breaches the contract terms, and provide... 7 Agriculture 6 2010-01-01 2010-01-01 false Contract provisions. 550.50 Section 550.50 Agriculture... Procurement Standards § 550.50 Contract provisions. The recipient shall include, in addition to provisions to...

26 CFR 1.988-3 - Character of exchange gain or loss.

Code of Federal Regulations, 2010 CFR

2010-04-01

... bona fide mistake made in good faith is on the taxpayer. (5) Independent verification—(i) Effect of... transaction (including a section 1256 contract that is also a section 988 transaction) shall be characterized... on certain identified forward contracts, futures contracts and option contracts as capital gain or...

48 CFR 246.710 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracts that include the clause at 252.227-7013, Rights in Technical Data and Computer Software, when... Alternate I when extended liability is desired and a fixed price incentive contract is contemplated. (3) Use... and a firm fixed price contract is contemplated. (4) Use the clause at 252.246-7002, Warranty of...

28 CFR Appendix A to Part 70 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-07-01

... NON-PROFIT ORGANIZATIONS Pt. 70, App. A Appendix A to Part 70—Contract Provisions All contracts, awarded by a recipient including small purchases, must contain the following provisions as applicable: 1... purchases of supplies or materials or articles ordinarily available on the open market, or contracts for...

38 CFR Appendix A to Part 49 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-07-01

..., HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 49, App. A Appendix A to Part 49—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following provisions as... purchases of supplies or materials or articles ordinarily available on the open market, or contracts for...

38 CFR 17.142 - Authority to approve sharing agreements, contracts for scarce medical specialist services and...

Code of Federal Regulations, 2010 CFR

2010-07-01

... sharing agreements, contracts for scarce medical specialist services and contracts for other medical... medical specialist services and contracts for other medical services. The Under Secretary for Health is... specialist services at Department of Veterans Affairs health care facilities (including, but not limited to...

48 CFR 5.703 - Definition.

Code of Federal Regulations, 2011 CFR

2011-10-01

... PUBLICIZING CONTRACT ACTIONS Publicizing Requirements under the American Recovery and Reinvestment Act of 2009 5.703 Definition. As used in this subpart— Task or delivery order contract means a “delivery order contract,” and a “task order contract,” as defined in 16.501-1. For example, it includes Governmentwide...

48 CFR 5.703 - Definition.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PUBLICIZING CONTRACT ACTIONS Publicizing Requirements under the American Recovery and Reinvestment Act of 2009 5.703 Definition. As used in this subpart— Task or delivery order contract means a “delivery order contract,” and a “task order contract,” as defined in 16.501-1. For example, it includes Governmentwide...

7 CFR 1718.103 - Loan contract provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... contract and the remedies available to RUS; (v) Applicability of state and federal laws; (w) Severability... loan contract; (y) Requirements relating to federal laws and regulations, including but not limited to... 7 Agriculture 11 2010-01-01 2010-01-01 false Loan contract provisions. 1718.103 Section 1718.103...

Presence and Absence of Muscle Contraction Elicited by Peripheral Nerve Electrical Stimulation Differentially Modulate Primary Motor Cortex Excitability.

PubMed

Sasaki, Ryoki; Kotan, Shinichi; Nakagawa, Masaki; Miyaguchi, Shota; Kojima, Sho; Saito, Kei; Inukai, Yasuto; Onishi, Hideaki

2017-01-01

Modulation of cortical excitability by sensory inputs is a critical component of sensorimotor integration. Sensory afferents, including muscle and joint afferents, to somatosensory cortex (S1) modulate primary motor cortex (M1) excitability, but the effects of muscle and joint afferents specifically activated by muscle contraction are unknown. We compared motor evoked potentials (MEPs) following median nerve stimulation (MNS) above and below the contraction threshold based on the persistence of M-waves. Peripheral nerve electrical stimulation (PES) conditions, including right MNS at the wrist at 110% motor threshold (MT; 110% MNS condition), right MNS at the index finger (sensory digit nerve stimulation [DNS]) with stimulus intensity approximately 110% MNS (DNS condition), and right MNS at the wrist at 90% MT (90% MNS condition) were applied. PES was administered in a 4 s ON and 6 s OFF cycle for 20 min at 30 Hz. In Experiment 1 ( n = 15), MEPs were recorded from the right abductor pollicis brevis (APB) before (baseline) and after PES. In Experiment 2 ( n = 15), M- and F-waves were recorded from the right APB. Stimulation at 110% MNS at the wrist evoking muscle contraction increased MEP amplitudes after PES compared with those at baseline, whereas DNS at the index finger and 90% MNS at the wrist not evoking muscle contraction decreased MEP amplitudes after PES. M- and F-waves, which reflect spinal cord or muscular and neuromuscular junctions, did not change following PES. These results suggest that muscle contraction and concomitant muscle/joint afferent inputs specifically enhance M1 excitability.

Presence and Absence of Muscle Contraction Elicited by Peripheral Nerve Electrical Stimulation Differentially Modulate Primary Motor Cortex Excitability

PubMed Central

Sasaki, Ryoki; Kotan, Shinichi; Nakagawa, Masaki; Miyaguchi, Shota; Kojima, Sho; Saito, Kei; Inukai, Yasuto; Onishi, Hideaki

2017-01-01

Modulation of cortical excitability by sensory inputs is a critical component of sensorimotor integration. Sensory afferents, including muscle and joint afferents, to somatosensory cortex (S1) modulate primary motor cortex (M1) excitability, but the effects of muscle and joint afferents specifically activated by muscle contraction are unknown. We compared motor evoked potentials (MEPs) following median nerve stimulation (MNS) above and below the contraction threshold based on the persistence of M-waves. Peripheral nerve electrical stimulation (PES) conditions, including right MNS at the wrist at 110% motor threshold (MT; 110% MNS condition), right MNS at the index finger (sensory digit nerve stimulation [DNS]) with stimulus intensity approximately 110% MNS (DNS condition), and right MNS at the wrist at 90% MT (90% MNS condition) were applied. PES was administered in a 4 s ON and 6 s OFF cycle for 20 min at 30 Hz. In Experiment 1 (n = 15), MEPs were recorded from the right abductor pollicis brevis (APB) before (baseline) and after PES. In Experiment 2 (n = 15), M- and F-waves were recorded from the right APB. Stimulation at 110% MNS at the wrist evoking muscle contraction increased MEP amplitudes after PES compared with those at baseline, whereas DNS at the index finger and 90% MNS at the wrist not evoking muscle contraction decreased MEP amplitudes after PES. M- and F-waves, which reflect spinal cord or muscular and neuromuscular junctions, did not change following PES. These results suggest that muscle contraction and concomitant muscle/joint afferent inputs specifically enhance M1 excitability. PMID:28392766

Government Contract Law (9th Edition)

DTIC Science & Technology

1987-04-01

This Ninth Edition, like its predecessors, will serve as the textbook for the Government Contract Law taught at the School of Systems and Logistics...drawn from Government Contract Law -Cases, 1987 edition, for a rounded approach to the subject. This edition of the text includes coverage of the...Government Contract Law complements the Federal Acquisition Regulation and provides a preventive law treatment for contracting personnel. While it may

[Social exchange and inference: an experimental study with the Wason selection task].

PubMed

Hayashi, N

2001-04-01

Social contract theory (Cosmides, 1989) posits that the human mind was equipped with inference faculty specialized for cheater detection. Cosmides (1989) conducted a series of experiments employing the Wason selection task to demonstrate that her social contract theory could account for the content effects reported in the literature. The purpose of this study was to investigate the possibility that the results were due to experimental artifacts. In the current experiment, the subject was given two versions of the Wason task that contained no social exchange context, but included an instruction implying him/her to look for something, together with the cassava root and the abstract versions used by Cosmides (1989). Results showed that the two versions with no social exchange context produced the same response pattern observed in the original study. It may be concluded that the subject's perception of the rule as a social contract was not necessary to obtain the original results, and that an instruction implying that he/she should look for something was sufficient.

48 CFR 49.202 - Profit.

Code of Federal Regulations, 2010 CFR

2010-10-01

....202 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS Additional Principles for Fixed-Price Contracts Terminated for Convenience 49.202...) Character and difficulty of subcontracting, including selection, placement, and management of subcontracts...

Science Methods by Learning Contract

ERIC Educational Resources Information Center

Heimler, Charles H.; Cunningham, James

1972-01-01

Describes a program employed for teaching a science methods course. The goal of individualized instruction may be achieved by adopting a learning contract system. The appendix includes examples of contracts used in this program. (PS)

48 CFR 227.7102-4 - Contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... processes. (2) Use the clause at 252.227-7015 with its Alternate I in solicitations and contracts, including..., Validation of Restrictive Markings on Technical Data, in solicitations and contracts using FAR part 12...

48 CFR 227.7102-4 - Contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... processes. (2) Use the clause at 252.227-7015 with its Alternate I in solicitations and contracts, including..., Validation of Restrictive Markings on Technical Data, in solicitations and contracts using FAR part 12...

Physician Payment Contracts in the Presence of Moral Hazard and Adverse Selection: The Theory and Its Application in Ontario.

PubMed

Kantarevic, Jasmin; Kralj, Boris

2016-10-01

We develop a stylized principal-agent model with moral hazard and adverse selection to provide a unified framework for understanding some of the most salient features of the recent physician payment reform in Ontario and its impact on physician behavior. These features include the following: (i) physicians can choose a payment contract from a menu that includes an enhanced fee-for-service contract and a blended capitation contract; (ii) the capitation rate is higher, and the cost-reimbursement rate is lower in the blended capitation contract; (iii) physicians sort selectively into the contracts based on their preferences; and (iv) physicians in the blended capitation model provide fewer services than physicians in the enhanced fee-for-service model. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

Power and Control: Contracts and the Patient-Physician Relationship

PubMed Central

Lieber, Sarah R.; Kim, Scotty Y.; Volk, Michael L.

2011-01-01

Contracts with patients have become increasingly common in clinical practice and the medical literature. These include behavioral contracts for managing “difficult patients” 1, opioid contracts2–5, suicide prevention contracts6,7, and healthy living contracts8. Some physician practices have even asked patients to sign contracts promising not to litigate or post defamatory comments on the Internet9. Despite widespread adoption, few have stopped to consider the potential risks and ethical concerns with using these documents. This perspective will describe how patient contracts are ultimately about power and control, and if not used carefully could damage the patient-physician relationship. PMID:22093528

Multilayer Pressure Vessel Materials Testing and Analysis. Phase 1

NASA Technical Reports Server (NTRS)

Cardinal, Joseph W.; Popelar, Carl F.; Page, Richard A.

2014-01-01

To provide NASA a comprehensive suite of materials strength, fracture toughness and crack growth rate test results for use in remaining life calculations for aging multilayer pressure vessels, Southwest Research Institute (R) (SwRI) was contracted in two phases to obtain relevant material property data from a representative vessel. This report describes Phase 1 of this effort which includes a preliminary material property assessment as well as a fractographic, fracture mechanics and fatigue crack growth analyses of an induced flaw in the outer shell of a representative multilayer vessel that was subjected to cyclic pressure test. SwRI performed this Phase 1 effort under contract to the Digital Wave Corporation in support of their contract to Jacobs ATOM for the NASA Ames Research Center.

Young People's Views on Distributive Justice, Rights, and Obligations: A Cross-Cultural Study.

ERIC Educational Resources Information Center

Jonsson, Britta; Flanagan, Constance

2000-01-01

Presents the results from a cross-cultural research project that explored adolescents' interpretation of the social contract (obligations, rights, and responsibilities between individuals and society) in seven countries, including Australia, Bulgaria, Czech Republic, Hungary, Russia, Sweden, and the United States. Includes appendices and…

Advanced transportation system studies technical area 2 (TA-2): Heavy lift launch vehicle development. volume 3; Program Cost estimates

NASA Technical Reports Server (NTRS)

McCurry, J. B.

1995-01-01

The purpose of the TA-2 contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. The basic period of performance of the TA-2 contract was from May 1992 through May 1993. No-cost extensions were exercised on the contract from June 1993 through July 1995. This document is part of the final report for the TA-2 contract. The final report consists of three volumes: Volume 1 is the Executive Summary, Volume 2 is Technical Results, and Volume 3 is Program Cost Estimates. The document-at-hand, Volume 3, provides a work breakdown structure dictionary, user's guide for the parametric life cycle cost estimation tool, and final report developed by ECON, Inc., under subcontract to Lockheed Martin on TA-2 for the analysis of heavy lift launch vehicle concepts.

Contraction induced h reflexes in the diagnosis of cervical radiculopathy.

PubMed

Bodofsky, Elliot B; Campellone, Joseph V; Cohen, Stephen J; Caten, Holly N; Schindelheim, Adam M

2015-06-01

To determine whether Contraction Induced H Reflexes (CIHR) can accurately detect cervical radiculopathy. Comparison of CIHR results with Needle Electromyography at academic outpatient Electromyography/Nerve Conduction laboratories. Participants were all patients over 18 with a needle electromyography diagnosis of cervical radiculopathy. Patients were tested for CIHR in at least two upper extremity muscles in electromyographically proven myotomes bilaterally. Patients were requested to perform a moderate contraction while stimulus was applied proximally (elbow or Erb's point). Outcome measures included H Reflex onset latency and side-to-side latency differences. These were compared against previously established normal values. Overall, 10 of 15 patients who met criteria for cervical radiculopathy showed CIHR abnormalities (sensitivity = 67%; 95% confidence interval, 43-91). Counting each side and level separately, CIHR identified 16/27 radiculopathies (sensitivity = 59.2%; 95% confidence interval, 40.6-77.8). Contraction Induced H Reflexes identified 1 possible radiculopathy not seen on electromyography (specificity = 98%; 95% confidence interval, 95-100). Contraction induced H Reflexes have a sensitivity and specificity for cervical radiculopathy similar to the resting Gastroc-Soleus H Reflex.

48 CFR 731.771 - Bid and proposal costs.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Government and non-Government grants, contracts and other agreements, including the development of scientific... method, the results obtained may be accepted only if found to be reasonable and equitable. (b) Bid and...

48 CFR 731.771 - Bid and proposal costs.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Government and non-Government grants, contracts and other agreements, including the development of scientific... method, the results obtained may be accepted only if found to be reasonable and equitable. (b) Bid and...

48 CFR 731.771 - Bid and proposal costs.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Government and non-Government grants, contracts and other agreements, including the development of scientific... method, the results obtained may be accepted only if found to be reasonable and equitable. (b) Bid and...

48 CFR 731.771 - Bid and proposal costs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Government and non-Government grants, contracts and other agreements, including the development of scientific... method, the results obtained may be accepted only if found to be reasonable and equitable. (b) Bid and...

48 CFR 731.771 - Bid and proposal costs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Government and non-Government grants, contracts and other agreements, including the development of scientific... method, the results obtained may be accepted only if found to be reasonable and equitable. (b) Bid and...

75 FR 40005 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Order Granting...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-13

... including, but not limited to, stock index futures contracts, options on futures, options on securities and... holding and/ or managing portfolios or baskets of securities, commodity futures contracts, options on commodity futures contracts, swaps, forward contracts and/or options on physical commodities and/or non-U.S...

41 CFR 60-741.4 - Coverage and waivers.

Code of Federal Regulations, 2011 CFR

2011-07-01

... facilitated, performance of the contract or a provision of the contract; or (B) The cost or a portion of the... allocable in whole or in part as a direct cost to any Government contract, and only a de minimis (less than... quantities. With respect to indefinite delivery-type contracts and subcontracts (including, but not limited...

29 CFR 95.48 - Contract provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... in instances in which a contractor violates or breaches the contract terms, and provide for such... 29 Labor 1 2010-07-01 2010-07-01 true Contract provisions. 95.48 Section 95.48 Labor Office of the... Standards § 95.48 Contract provisions. The recipient shall include, in addition to provisions to define a...

48 CFR 252.225-7032 - Waiver of United Kingdom Levies-Evaluation of offers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... of a contract, the U.S. Government reserves the right to reduce the contract price by the amount of... Levies—Evaluation of Offers (APR 2003) (a) Offered prices for contracts or subcontracts with United... offeror shall identify to the Contracting Officer all levies included in the offered price by describing...

36 CFR 51.74 - When may a concession contract be terminated by the Director?

Code of Federal Regulations, 2014 CFR

2014-07-01

... contract be terminated by the Director? 51.74 Section 51.74 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR CONCESSION CONTRACTS Concession Contract Provisions § 51.74... include, but are not limited to, protecting, conserving, and preserving park area resources and providing...

36 CFR 51.74 - When may a concession contract be terminated by the Director?

Code of Federal Regulations, 2013 CFR

2013-07-01

... contract be terminated by the Director? 51.74 Section 51.74 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR CONCESSION CONTRACTS Concession Contract Provisions § 51.74... include, but are not limited to, protecting, conserving, and preserving park area resources and providing...

36 CFR 51.74 - When may a concession contract be terminated by the Director?

Code of Federal Regulations, 2011 CFR

2011-07-01

... contract be terminated by the Director? 51.74 Section 51.74 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR CONCESSION CONTRACTS Concession Contract Provisions § 51.74... include, but are not limited to, protecting, conserving, and preserving park area resources and providing...

36 CFR 51.74 - When may a concession contract be terminated by the Director?

Code of Federal Regulations, 2012 CFR

2012-07-01

... contract be terminated by the Director? 51.74 Section 51.74 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR CONCESSION CONTRACTS Concession Contract Provisions § 51.74... include, but are not limited to, protecting, conserving, and preserving park area resources and providing...

36 CFR 51.74 - When may a concession contract be terminated by the Director?

Code of Federal Regulations, 2010 CFR

2010-07-01

... contract be terminated by the Director? 51.74 Section 51.74 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR CONCESSION CONTRACTS Concession Contract Provisions § 51.74... include, but are not limited to, protecting, conserving, and preserving park area resources and providing...

41 CFR 102-117.65 - What terms and conditions must all rate tenders or contracts include?

Code of Federal Regulations, 2010 CFR

2010-07-01

... statutes (49 U.S.C. 10721 or 13712), property must be shipped by or for the Government and the rate tender... provider by the consignor or consignee are for the benefit of the Government. (e) When using a rate tender... conditions must all rate tenders or contracts include? 102-117.65 Section 102-117.65 Public Contracts and...

The Contract Management Body of Knowledge: A Comparison of Contracting Competencies

DTIC Science & Technology

2013-12-01

SME subject matter expert SOW statement of work TINA Truth in Negotiations Act UCC uniform commercial code WBS work breakdown structure xv...documents whose terms and condition are legally enforceable. Sources of law and guidance covered include the uniform commercial code ( UCC ), Federal...contracting including the uniform commercial code ( UCC ), Federal Acquisition Regulation (FAR), as well as various other laws pertaining to both

A comparison of the costs of forest service and contract fire crews in the Pacific Northwest.

Treesearch

Geoffrey H. Donovan

2005-01-01

Rising wildfire suppression expenditures on public land in the United States have led to increased scrutiny of wildfire management practices. One area that has received particular attention is the Forest Service's increasing reliance on contract fire crews. Because a contract crew rate includes several costs that are not included in the wage costs of a Forest...

The INCENTIVE protocol: an evaluation of the organisation and delivery of NHS dental healthcare to patients-innovation in the commissioning of primary dental care service delivery and organisation in the UK.

PubMed

Pavitt, Sue H; Baxter, Paul D; Brunton, Paul A; Douglas, Gail; Edlin, Richard; Gibson, Barry J; Godson, Jenny; Hall, Melanie; Porritt, Jenny; Robinson, Peter G; Vinall, Karen; Hulme, Claire

2014-09-17

In England, in 2006, new dental contracts devolved commissioning of dental services locally to Primary Care Trusts to meet the needs of their local population. The new national General Dental Services contracts (nGDS) were based on payment for Units of Dental Activity (UDAs) awarded in three treatment bands based on complexity of care. Recently, contract currency in UK dentistry is evolving from UDAs based on volume and case complexity towards 'blended contracts' that include incentives linked with key performance indicators such as quality and improved health outcome. Overall, evidence of the effectiveness of incentive-driven contracting of health providers is still emerging. The INCENTIVE Study aims to evaluate a blended contract model (incentive-driven) compared to traditional nGDS contracts on dental service delivery in practices in West Yorkshire, England. The INCENTIVE model uses a mixed methods approach to comprehensively evaluate a new incentive-driven model of NHS dental service delivery. The study includes 6 dental surgeries located across three newly commissioned dental practices (blended contract) and three existing traditional practices (nGDS contracts). The newly commissioned practices have been matched to traditional practices by deprivation index, age profile, ethnicity, size of practice and taking on new patients. The study consists of three interlinked work packages: a qualitative study to explore stakeholder perspectives of the new service delivery model; an effectiveness study to assess the INCENTIVE model in reducing the risk of and amount of dental disease and enhance oral health-related quality of life in patients; and an economic study to assess cost-effectiveness of the INCENTIVE model in relation to clinical status and oral health-related quality of life. The study has been approved by NRES Committee London, Bromley. The results of this study will be disseminated at national and international conferences and in international journals. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Automatic and quantitative measurement of collagen gel contraction using model-guided segmentation

NASA Astrophysics Data System (ADS)

Chen, Hsin-Chen; Yang, Tai-Hua; Thoreson, Andrew R.; Zhao, Chunfeng; Amadio, Peter C.; Sun, Yung-Nien; Su, Fong-Chin; An, Kai-Nan

2013-08-01

Quantitative measurement of collagen gel contraction plays a critical role in the field of tissue engineering because it provides spatial-temporal assessment (e.g., changes of gel area and diameter during the contraction process) reflecting the cell behavior and tissue material properties. So far the assessment of collagen gels relies on manual segmentation, which is time-consuming and suffers from serious intra- and inter-observer variability. In this study, we propose an automatic method combining various image processing techniques to resolve these problems. The proposed method first detects the maximal feasible contraction range of circular references (e.g., culture dish) and avoids the interference of irrelevant objects in the given image. Then, a three-step color conversion strategy is applied to normalize and enhance the contrast between the gel and background. We subsequently introduce a deformable circular model which utilizes regional intensity contrast and circular shape constraint to locate the gel boundary. An adaptive weighting scheme was employed to coordinate the model behavior, so that the proposed system can overcome variations of gel boundary appearances at different contraction stages. Two measurements of collagen gels (i.e., area and diameter) can readily be obtained based on the segmentation results. Experimental results, including 120 gel images for accuracy validation, showed high agreement between the proposed method and manual segmentation with an average dice similarity coefficient larger than 0.95. The results also demonstrated obvious improvement in gel contours obtained by the proposed method over two popular, generic segmentation methods.

25 CFR 273.18 - Additional requirements for education plan.

Code of Federal Regulations, 2012 CFR

2012-04-01

... EDUCATION ASSISTANCE ACT PROGRAM EDUCATION CONTRACTS UNDER JOHNSON-O'MALLEY ACT Application Process § 273.18... needed to carry out the contract. (o) State the period of contract term requested. (p) Include the...

25 CFR 273.18 - Additional requirements for education plan.

Code of Federal Regulations, 2013 CFR

2013-04-01

... EDUCATION ASSISTANCE ACT PROGRAM EDUCATION CONTRACTS UNDER JOHNSON-O'MALLEY ACT Application Process § 273.18... needed to carry out the contract. (o) State the period of contract term requested. (p) Include the...

25 CFR 273.18 - Additional requirements for education plan.

Code of Federal Regulations, 2014 CFR

2014-04-01

... EDUCATION ASSISTANCE ACT PROGRAM EDUCATION CONTRACTS UNDER JOHNSON-O'MALLEY ACT Application Process § 273.18... needed to carry out the contract. (o) State the period of contract term requested. (p) Include the...

48 CFR 1415.404-4 - Profit.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 1415.404-4 Profit. (a) DOI's policy is to use a... also refer to the Armed Services Pricing Manual (ASPM No. 1). The “Other Costs” factor shall include...

The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release.

PubMed

Obis, Teresa; Besalduch, Núria; Hurtado, Erica; Nadal, Laura; Santafe, Manel M; Garcia, Neus; Tomàs, Marta; Priego, Mercedes; Lanuza, Maria A; Tomàs, Josep

2015-02-10

Protein kinase C (PKC) regulates a variety of neural functions, including neurotransmitter release. Although various PKC isoforms can be expressed at the synaptic sites and specific cell distribution may contribute to their functional diversity, little is known about the isoform-specific functions of PKCs in neuromuscular synapse. The present study is designed to examine the location of the novel isoform nPKCε at the neuromuscular junction (NMJ), their synaptic activity-related expression changes, its regulation by muscle contraction, and their possible involvement in acetylcholine release. We use immunohistochemistry and confocal microscopy to demonstrate that the novel isoform nPKCε is exclusively located in the motor nerve terminals of the adult rat NMJ. We also report that electrical stimulation of synaptic inputs to the skeletal muscle significantly increased the amount of nPKCε isoform as well as its phosphorylated form in the synaptic membrane, and muscle contraction is necessary for these nPKCε expression changes. The results also demonstrate that synaptic activity-induced muscle contraction promotes changes in presynaptic nPKCε through the brain-derived neurotrophic factor (BDNF)-mediated tyrosine kinase receptor B (TrkB) signaling. Moreover, nPKCε activity results in phosphorylation of the substrate MARCKS involved in actin cytoskeleton remodeling and related with neurotransmission. Finally, blocking nPKCε with a nPKCε-specific translocation inhibitor peptide (εV1-2) strongly reduces phorbol ester-induced ACh release potentiation, which further indicates that nPKCε is involved in neurotransmission. Together, these results provide a mechanistic insight into how synaptic activity-induced muscle contraction could regulate the presynaptic action of the nPKCε isoform and suggest that muscle contraction is an important regulatory step in TrkB signaling at the NMJ.

Study of Photon Emission with the Fission Event Generator FREYA

NASA Astrophysics Data System (ADS)

Vogt, Ramona; Randrup, Jorgen

2017-09-01

The event-by-event fission model FREYA is employed to study photon observables. The model has been expanded beyond the simple statistical photon emission reported previously to include the discrete RIPL-3 lines. We update these prior results and discuss the sensitivity of the results to the FREYA input parameters sensitive to photon observables. The work of R.V. was performed under the auspices of the U.S. DOE by LLNL Contract DE-AC52-07NA27344, that of J.R. by LBNL Contract DE-AC02-05CH11231. The authors thank NNSA Defense Nuclear Nonproliferation R&D for support.

Fluid Dynamics Lagrangian Simulation Model

NASA Astrophysics Data System (ADS)

Hyman, Ellis

1994-02-01

The work performed by Science Applications International Corporation (SAIC) on this contract, Fluid Dynamics Lagrangian Simulation Model, Contract Number N00014-89-C-2106, SAIC Project Number 01-0157-03-0768, focused on a number of research topics in fluid dynamics. The work was in support of the programs of NRL's Laboratory for Computational Physics and Fluid Dynamics and covered the period from 10 September 1989 to 9 December 1993. In the following sections, we describe each of the efforts and the results obtained. Much of the research work has resulted in journal publications. These are included in Appendices of this report for which the reader is referred for complete details.

Functional implications of muscle co-contraction during gait in advanced age.

PubMed

Lo, Justine; Lo, On-Yee; Olson, Erin A; Habtemariam, Daniel; Iloputaife, Ikechukwu; Gagnon, Margaret M; Manor, Brad; Lipsitz, Lewis A

2017-03-01

Older adults often exhibit high levels of lower extremity muscle co-contraction, which may be the cause or effect of age-related impairments in gait and associated falls. Normal gait requires intact executive function and thus can be slowed by challenging executive resources available to the neuromuscular system through the performance of a dual task. We therefore investigated associations between lower limb co-contraction and gait characteristics under normal and dual task conditions in healthy older adults (85.4±5.9years). We hypothesized that greater co-contraction is associated with slower gait speed during dual task conditions that stress executive and attentional abilities. Co-contraction was quantified during different phases of the gait cycle using surface electromyography (EMG) signals obtained from the anterior tibialis and lateral gastrocnemius while walking at preferred speed during normal and dual task conditions. Variables included the time difference to complete the Trail Making Test A and B (ΔTMT) and gait measures during normal or dual task walking. Higher co-contraction levels during the swing phase of both normal and dual task walking were associated with longer ΔTMT (normal: R 2 =0.25, p=0.02; dual task: R 2 =0.27, p=0.01). Co-contraction was associated with gait measures during dual task walking only; greater co-contraction levels during stride and stance were associated with slower gait speed (stride: R 2 =0.38, p=0.04; stance: R 2 =0.38, p=0.04), and greater co-contraction during stride was associated with longer stride time (R 2 =0.16, p=0.03). Our results suggest that relatively high lower limb co-contraction may explain some of the mobility impairments associated with the conduct of executive tasks in older adults. Copyright © 2017 Elsevier B.V. All rights reserved.

Contracting private sector providers for public sector health services in Jalisco, Mexico: perspectives of system actors

PubMed Central

Nigenda, Gustavo H; González, Luz María

2009-01-01

Introduction Contracting out health services is a strategy that many health systems in the developing world are following, despite the lack of decisive evidence that this is the best way to improve quality, increase efficiency and expand coverage. A large body of literature has appeared in recent years focusing on the results of several contracting strategies, but very few papers have addressed aspects of the managerial process and how this can affect results. Case description This paper describes and analyses the perceptions and opinions of managers and workers about the benefits and challenges of the contracting model that has been in place for almost 10 years in the State of Jalisco, Mexico. Both qualitative and quantitative information was collected. An open-ended questionnaire was used to obtain information from a group of managers, while information provided by a self-selected group of workers was collected via a closed-ended questionnaire. The analysis contrasted the information obtained from each source. Discussion and Evaluation Findings show that perceptions of managers and workers vary for most of the items studied. For managers the model has been a success, as it has allowed for expansion of coverage based on a cost-effective strategy, while for workers the model also possesses positive elements but fails to provide fair labour relationships, which negatively affects their performance. Conclusion Perspectives of the two main groups of actors in Jalisco's contracting model are important in the design and adjustment of an adequate contracting model that includes managerial elements to give incentives to worker performance, a key element necessary to achieve the model's ultimate objectives. Lessons learnt from this study could be relevant for the experience of contracting models in other developing countries. PMID:19849831

Earth resources-regional transfer activity contracts review

NASA Technical Reports Server (NTRS)

Bensko, J., Jr.; Daniels, J. L.; Downs, S. W., Jr.; Jones, N. L.; Morton, R. R.; Paludan, C. T.

1977-01-01

A regional transfer activity contracts review held by the Earth Resources Office was summarized. Contracts in the earth resources field primarily directed toward applications of satellite data and technology in solution of state and regional problems were reviewed. A summary of the progress of each contract was given in order to share experiences of researchers across a seven state region. The region included Missouri, Kentucky, Tennessee, Mississippi, Alabama, Georgia, and North Carolina. Research in several earth science disciplines included forestry, limnology, water resources, land use, geology, and mathematical modeling. The use of computers for establishment of information retrieval systems was also emphasized.

Implementation of warranties in state contracts for highway construction.

DOT National Transportation Integrated Search

2012-04-01

In 1997, The Louisiana House of Representatives passed Bill Number 1698, which addresses warranties in state : contracts for highway construction. This bill stated that every contract for the construction of or improvements to : highways will include...

Private Health Plans’ Contracts with Managed Behavioral Healthcare Organizations

PubMed Central

Garnick, Deborah W.; Horgan, Constance M.; Merrick, Elizabeth L.; Hodgkin, Dominic; Reif, Sharon; Quinn, Amity E.; Stewart, Maureen; Creedon, Timothy B.

2015-01-01

Contracts between health plans and managed behavioral health care organizations (MBHOs) influence access and quality of behavioral health care. This report presents information on performance requirements, information sharing, and financial risk from a nationally representative survey of private health plans. Most contracts include geographic access to providers (93.3%) and NCQA’s performance standards (84.2%). Health plans and MBHOs share data (99.0%), generally by the MBHO sending information to the health plan (96.3%). About a quarter of contracts impose financial penalties (23.0%), but few include incentives related to performance standards (<1.0%). Contract terms can shape the provision of behavioral health services in response to changes such as parity legislation or health reform. If current trends continue towards increases in value-based purchasing in the privately financed behavioral health sector, the focus on quality in contracts between health plans and MBHOs will be critical to understand. PMID:26276421

48 CFR 536.213-371 - Bids that include options.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Bids that include options... Contracting for Construction 536.213-371 Bids that include options. (a) Subject to the limitations in paragraph (c) of this section, you may include options in contracts if it is in the Government's interest...

75 FR 33882 - Self-Regulatory Organizations; NYSE Amex LLC and NYSE Arca, Inc.; Order Granting Approval of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-15

... contracts, options on commodity futures contracts, swaps, forward contracts and/or options on physical.... \\8\\ 17 CFR 242.600. \\9\\ NYSE Amex Rule 915 also includes stock index futures contracts and options on... Approval of Proposed Rule Changes Relating to Listing and Trading Options on the ETFS Palladium Trust and...

48 CFR 970.2904-1 - Management and operating contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... contracts. (a) Pursuant to 48 CFR 29.401-4(b), the clause at 48 CFR 52.229-10, State of New Mexico Gross... conditions stated. The contracting officer shall modify paragraph (b) of the clause to replace the phrase “Allowable Cost and Payment” with the phrase “Payments and Advances.” (b) Contracting officers shall include...

48 CFR 32.405 - Applying Pub. L. 85-804 to advance payments under sealed bid contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... advance payments under sealed bid contracts. 32.405 Section 32.405 Federal Acquisition Regulations System... Non-Commercial Items 32.405 Applying Pub. L. 85-804 to advance payments under sealed bid contracts. (a... provisions of law relating to contracts, as explained in 50.101-1(a), also include making advance payments...

21 CFR 200.10 - Contract facilities (including consulting laboratories) utilized as extramural facilities by...

Code of Federal Regulations, 2010 CFR

2010-04-01

... (IND) Application, any information obtained during the inspection of an extramural facility having a... Administration does not consider results of validation studies of analytical and assay methods and control...

Final Report on the Audit of Architect-Engineer Contracting at the Officer in Charge of Construction, Naval Facilities Engineering Command Contracts, Mediterranean, Madrid, Spain

DTIC Science & Technology

1990-11-30

This is our final report on the audit of Architect-Engineer Contracting for the Officer in Charge of Construction, Naval Facilities Engineering...Command Contracts, Mediterranean, for your information and use. This is the fourth in a series of reports issued as part of the audit of architect-engineer...A-E) contracting. The Contract Management Directorate made the audit from August 1989 through July 1990. When we expanded the audit scope to include

Adverse or acceptable: negotiating access to a post-apartheid health care contract

PubMed Central

2014-01-01

Background As in many fragile and post-conflict countries, South Africa’s social contract has formally changed from authoritarianism to democracy, yet access to services, including health care, remains inequitable and contested. We examine access barriers to quality health services and draw on social contract theory to explore ways in which a post-apartheid health care contract is narrated, practiced and negotiated by patients and providers. We consider implications for conceptualizing and promoting more inclusive, equitable health services in a post-conflict setting. Methods Using in-depth interviews with 45 patients and 67 providers, and field observations from twelve health facilities in one rural and two urban sub-districts, we explore access narratives of those seeking and delivering – negotiating - maternal health, tuberculosis and antiretroviral services in South Africa. Results Although South Africa’s right to access to health care is constitutionally guaranteed, in practice, a post-apartheid health care contract is not automatically or unconditionally inclusive. Access barriers, including poverty, an under-resourced, hierarchical health system, the nature of illness and treatment, and negative attitudes and actions, create conditions for insecure or adverse incorporation into this contract, or even exclusion (sometimes temporary) from health care services. Such barriers are exacerbated by differences in the expectations that patients and providers have of each other and the contract, leading to differing, potentially conflicting, identities of inclusion and exclusion: defaulting versus suffering patients, uncaring versus overstretched providers. Conversely, caring, respectful communication, individual acts of kindness, and institutional flexibility and leadership may mitigate key access barriers and limit threats to the contract, fostering more positive forms of inclusion and facilitating easier access to health care. Conclusions Building health in fragile and post-conflict societies requires the negotiation of a new social contract. Surfacing and engaging with differences in patient and provider expectations of this contract may contribute to more acceptable, accessible health care services. Additionally, the health system is well positioned to highlight and connect the political economy, institutions and social relationships that create and sustain identities of exclusion and inclusion – (re)politicise suffering - and co-ordinate and lead intersectoral action for overcoming affordability and availability barriers to inclusive and equitable health care services. PMID:24885882

78 FR 9865 - Air Carrier Contract Maintenance Requirements; Extension of Comment Period

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

..., RACCA believes the proposed rulemaking would result in significant unintended consequences, including greater operator cost and manpower requirements than those estimated in the NPRM, loss of efficiency, unbudgeted loss of aircraft availability, and a substantial additional workload for the FAA that would result...

Canadian policy makers' views on pharmaceutical reimbursement contracts involving confidential discounts from drug manufacturers.

PubMed

Morgan, Steven G; Thomson, Paige A; Daw, Jamie R; Friesen, Melissa K

2013-10-01

Pharmaceutical policy makers are increasingly negotiating reimbursement contracts that include confidential price terms that may be affected by drug utilization volumes, patterns, or outcomes. Though such contracts may offer a variety of benefits, including the ability to tie payment to the actual performance of a product, they may also create potential policy challenges. Through telephone interviews about this type of contract, we studied the views of officials in nine of ten Canadian provinces. Use of reimbursement contracts involving confidential discounts is new in Canada and ideas about power and equity emerged as cross-cutting themes in our interviews. Though confidential rebates can lower prices and thereby increase coverage of new medicines, several policy makers felt they had little power in the decision to negotiate rebates. Study participants explained that the recent rise in the use of rebates had been driven by manufacturers' pricing tactics and precedent set by other jurisdictions. Several policy makers expressed concerns that confidential rebates could result in inter-jurisdictional inequities in drug pricing and coverage. Policy makers also noted un-insured and under-insured patients must pay inflated "list prices" even if rebates are negotiated by drug plans. The establishment of policies for disciplined negotiations, inter-jurisdictional cooperation, and provision of drug coverage for all citizens are potential solutions to the challenges created by this new pharmaceutical pricing paradigm. Copyright © 2013 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

Implementation of warranties in state contracts for highway construction : tech summary.

DOT National Transportation Integrated Search

2012-04-01

In 1997, The Louisiana House of Representatives passed Bill Number 1698, which addresses warranties in state contracts : for highway construction. This bill states that every contract for the construction of or improvements to highways will : include...

Influence of Joint Angle on EMG-Torque Model During Constant-Posture, Torque-Varying Contractions.

PubMed

Liu, Pu; Liu, Lukai; Clancy, Edward A

2015-11-01

Relating the electromyogram (EMG) to joint torque is useful in various application areas, including prosthesis control, ergonomics and clinical biomechanics. Limited study has related EMG to torque across varied joint angles, particularly when subjects performed force-varying contractions or when optimized modeling methods were utilized. We related the biceps-triceps surface EMG of 22 subjects to elbow torque at six joint angles (spanning 60° to 135°) during constant-posture, torque-varying contractions. Three nonlinear EMG σ -torque models, advanced EMG amplitude (EMG σ ) estimation processors (i.e., whitened, multiple-channel) and the duration of data used to train models were investigated. When EMG-torque models were formed separately for each of the six distinct joint angles, a minimum "gold standard" error of 4.01±1.2% MVC(F90) resulted (i.e., error relative to maximum voluntary contraction at 90° flexion). This model structure, however, did not directly facilitate interpolation across angles. The best model which did so achieved a statistically equivalent error of 4.06±1.2% MVC(F90). Results demonstrated that advanced EMG σ processors lead to improved joint torque estimation as do longer model training durations.

Inhibition of adrenergic human prostate smooth muscle contraction by the inhibitors of c-Jun N-terminal kinase, SP600125 and BI-78D3.

PubMed

Strittmatter, F; Walther, S; Gratzke, C; Göttinger, J; Beckmann, C; Roosen, A; Schlenker, B; Hedlund, P; Andersson, K E; Stief, C G; Hennenberg, M

2012-07-01

BACKGROUND AND PURPOSE α(1) -Adrenoceptor-induced contraction of prostate smooth muscle is mediated by calcium- and Rho kinase-dependent mechanisms. In addition, other mechanisms, such as activation of c-jun N-terminal kinase (JNK) may be involved. Here, we investigated whether JNK participates in α(1)-adrenoceptor-induced contraction of human prostate smooth muscle. EXPERIMENTAL APPROACH Prostate tissue was obtained from patients undergoing radical prostatectomy. Effects of the JNK inhibitors SP600125 (50 µM) and BI-78D3 (30 µM) on contractions induced by phenylephrine, noradrenaline and electric field stimulation (EFS) were studied in myographic measurements. JNK activation by noradrenaline (30 µM) and phenylephrine (10 µM), and the effects of JNK inhibitors of c-Jun phosphorylation were assessed by Western blot analyses with phospho-specific antibodies. Expression of JNK was studied by immunohistochemistry and fluorescence double staining. KEY RESULTS The JNK inhibitors SP600125 and BI-78D3 reduced phenylephrine- and noradrenaline-induced contractions of human prostate strips. In addition, SP600125 reduced EFS-induced contraction of prostate strips. Stimulation of prostate tissue with noradrenaline or phenylephrine in vitro resulted in activation of JNK. Incubation of prostate tissue with SP600125 or BI-78D3 reduced the phosphorylation state of c-Jun. Immunohistochemical staining demonstrated the expression of JNK in smooth muscle cells of human prostate tissue. Fluorescence staining showed that α(1A)-adrenoceptors and JNK are expressed in the same cells. CONCLUSIONS AND IMPLICATIONS Activation of JNK is involved in α(1)-adrenoceptor-induced prostate smooth muscle contraction. Models of α(1)-adrenoceptor-mediated prostate smooth muscle contraction should include this JNK-dependent mechanism. © 2012 The Authors. British Journal of Pharmacology © 2012 The British Pharmacological Society.

The contract process: a methodology for negotiation. Part I.

PubMed

Kleinschmidt, W M

1990-05-01

This is the first of a three-part series on the contract process for acquiring a hospital information system product. Part One addresses negotiation methodology; points which will facilitate effective negotiation. Part Two will cover contract contents focusing on those topics which must be included in a good contract. Part Three will discuss contract philosophy and contract management; subjects which are critical to the good rapport buyers and vendors want. The adversarial approach to the contract process is not the best approach. Rather, the process should be treated as a step in the building of a partnership and relationship in which both parties win.

Level II scour analysis for Bridge 4 (MNTGTH00020004) on Town Highway 2, crossing Wade Brook, Montgomery, Vermont

USGS Publications Warehouse

Boehmler, Erick M.

1996-01-01

Total scour at a highway crossing is comprised of three components: 1) long-term streambed degradation; 2) contraction scour (due to accelerated flow caused by a reduction in flow area at a bridge) and; 3) local scour (caused by accelerated flow around piers and abutments). Total scour is the sum of the three components. Equations are available to compute depths for contraction and local scour and a summary of the results of these computations follows. Contraction scour for all modelled flows was 0.1 ft. The worst-case contraction scour occurred at the 100-year and 500-year discharges. Abutment scour ranged from 3.9 to 5.2 ft. The worst-case abutment scour also occurred at the 500-year discharge. Additional information on scour depths and depths to armoring are included in the section titled “Scour Results”. Scoured-streambed elevations, based on the calculated scour depths, are presented in tables 1 and 2. A cross-section of the scour computed at the bridge is presented in figure 8. Scour depths were calculated assuming an infinite depth of erosive material and a homogeneous particle-size distribution. It is generally accepted that the Froehlich equation (abutment scour) gives “excessively conservative estimates of scour depths” (Richardson and others, 1995, p. 47). Many factors, including historical performance during flood events, the geomorphic assessment, scour protection measures, and the results of the hydraulic analyses, must be considered to properly assess the validity of abutment scour results. Therefore, scour depths adopted by VTAOT may differ from the computed values documented herein, based on the consideration of additional contributing factors and experienced engineering judgement.

Level II scour analysis for Bridge 46 (CHELTH00680046) on Town Highway 68, crossing the First Branch of the White River, Chelsea, Vermont

USGS Publications Warehouse

Ivanoff, Michael A.; Song, Donald L.

1996-01-01

Total scour at a highway crossing is comprised of three components: 1) long-term streambed degradation; 2) contraction scour (due to accelerated flow caused by a reduction in flow area at a bridge) and; 3) local scour (caused by accelerated flow around piers and abutments). Total scour is the sum of the three components. Equations are available to compute depths for contraction and local scour and a summary of the results of these computations follows. Contraction scour for all modelled flows ranged from 0.9 to 2.6 ft. The worst-case contraction scour occurred at the 500-year discharge. Abutment scour ranged from 14.3 to 24.0 ft. The worst-case abutment scour occurred at the 500-year discharge. Additional information on scour depths and depths to armoring are included in the section titled “Scour Results”. Scoured-streambed elevations, based on the calculated scour depths, are presented in tables 1 and 2. A cross-section of the scour computed at the bridge is presented in figure 8. Scour depths were calculated assuming an infinite depth of erosive material and a homogeneous particle-size distribution. The left abutment sits atop a bedrock outcrop. The results of the calculated scour depths will be limited by the bedrock. It is generally accepted that the Froehlich equation (abutment scour) gives “excessively conservative estimates of scour depths” (Richardson and others, 1995, p. 47). Usually, computed scour depths are evaluated in combination with other information including (but not limited to) historical performance during flood events, the geomorphic stability assessment, existing scour protection measures, and the results of the hydraulic analyses. Therefore, scour depths adopted by VTAOT may differ from the computed values documented herein.

Space station final study report. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1987-01-01

Volume 1 of the Final Study Report provides an Executive Summary of the Phase B study effort conducted under contract NAS8-36526. Space station Phase B implementation resulted in the timely establishment of preliminary design tasks, including trades and analyses. A comprehensive summary of project activities in conducting this study effort is included.

Reflection spectra of etched FBGs under the influence of axial contraction and stress-induced index change.

PubMed

Yang, Hang-Zhou; Lim, Kok-Sing; Qiao, Xue-Guang; Chong, Wu-Yi; Cheong, Yew-Ken; Lim, Weng-Hong; Lim, Wei-Sin; Ahmad, Harith

2013-06-17

We present a new theoretical model for the broadband reflection spectra of etched FBGs which includes the effects of axial contraction and stress-induced index change. The reflection spectra of the etched FBGs with several different taper profiles are simulated based on the proposed model. In our observation, decaying exponential profile produces a broadband reflection spectrum with good uniformity over the range of 1540-1560 nm. An etched FBG with similar taper profile is fabricated and the experimental result shows good agreement with the theoretical model.

48 CFR 49.603-3 - Cost-reimbursement contracts-complete termination, if settlement includes cost.

Code of Federal Regulations, 2010 CFR

2010-10-01

... following: (1) The Contractor certifies that all contract termination inventory (including scrap) has been... the Contractor a certificate stating (i) that all subcontract termination inventory (including scrap... in its proposal. (3) The Contractor certifies that all items of termination inventory, the costs of...

48 CFR 47.207-3 - Description of shipment, origin, and destination.

Code of Federal Regulations, 2014 CFR

2014-10-01

... contracting officer shall include in solicitations full details regarding the location from which the freight is to be shipped. For example, if a single location is shown, furnish the shipper's name, street..., including boundaries and ZIP codes. (c) Description of the freight. The contracting officer shall include in...

48 CFR 47.207-3 - Description of shipment, origin, and destination.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracting officer shall include in solicitations full details regarding the location from which the freight is to be shipped. For example, if a single location is shown, furnish the shipper's name, street..., including boundaries and ZIP codes. (c) Description of the freight. The contracting officer shall include in...

48 CFR 47.207-3 - Description of shipment, origin, and destination.

Code of Federal Regulations, 2013 CFR

2013-10-01

... contracting officer shall include in solicitations full details regarding the location from which the freight is to be shipped. For example, if a single location is shown, furnish the shipper's name, street..., including boundaries and ZIP codes. (c) Description of the freight. The contracting officer shall include in...

48 CFR 47.207-3 - Description of shipment, origin, and destination.

Code of Federal Regulations, 2011 CFR

2011-10-01

... contracting officer shall include in solicitations full details regarding the location from which the freight is to be shipped. For example, if a single location is shown, furnish the shipper's name, street..., including boundaries and ZIP codes. (c) Description of the freight. The contracting officer shall include in...

48 CFR 47.207-3 - Description of shipment, origin, and destination.

Code of Federal Regulations, 2012 CFR

2012-10-01

... contracting officer shall include in solicitations full details regarding the location from which the freight is to be shipped. For example, if a single location is shown, furnish the shipper's name, street..., including boundaries and ZIP codes. (c) Description of the freight. The contracting officer shall include in...

Comparison of Navy and Private-Sector Construction Costs

DTIC Science & Technology

1997-09-01

contracts are comparable to private - sector construction costs. This report compares those costs. The report includes a description of the methodology...costs of complying with federal contracting requirements as compared with the costs of similar projects completed under typical private - sector contracts...The study found that the costs of facilities constructed under Navy contracts compare favorably to private - sector construction costs for similar

48 CFR 22.603 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Walsh-Healey Public Contracts Act 22.603 Applicability. The requirements in 22.602 apply to contracts (including for this purpose, indefinite-delivery contracts, basic ordering agreements, and blanket purchase agreements) and subcontracts under Section 8(a...

32 CFR 158.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... routinely are put in place to provide support to many newly fielded weapons systems, including aircraft, land combat vehicles, and automated command and control systems. Systems support contracting authority... generally has less control over systems support contracts than other types of contracts. Theater business...

32 CFR 158.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... routinely are put in place to provide support to many newly fielded weapons systems, including aircraft, land combat vehicles, and automated command and control systems. Systems support contracting authority... generally has less control over systems support contracts than other types of contracts. Theater business...

32 CFR 158.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... routinely are put in place to provide support to many newly fielded weapons systems, including aircraft, land combat vehicles, and automated command and control systems. Systems support contracting authority... generally has less control over systems support contracts than other types of contracts. Theater business...

48 CFR 970.5200 - Scope of subpart.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Section 970.5200 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY... hybrid contracts, in some cases including aspects of several FAR contract types, for example, supplies... their use despite the hybrid nature of the work required. To assist Departmental contracting personnel...

48 CFR 47.505 - Construction contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Construction contracts. 47... MANAGEMENT TRANSPORTATION Ocean Transportation by U.S.-Flag Vessels 47.505 Construction contracts. (a) Except as stated in paragraph (b) below, construction contractors, including subcontractors and suppliers...

48 CFR 47.505 - Construction contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Construction contracts. 47... MANAGEMENT TRANSPORTATION Ocean Transportation by U.S.-Flag Vessels 47.505 Construction contracts. (a) Except as stated in paragraph (b) below, construction contractors, including subcontractors and suppliers...

48 CFR 47.505 - Construction contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Construction contracts. 47... MANAGEMENT TRANSPORTATION Ocean Transportation by U.S.-Flag Vessels 47.505 Construction contracts. (a) Except as stated in paragraph (b) below, construction contractors, including subcontractors and suppliers...

48 CFR 47.505 - Construction contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Construction contracts. 47... MANAGEMENT TRANSPORTATION Ocean Transportation by U.S.-Flag Vessels 47.505 Construction contracts. (a) Except as stated in paragraph (b) below, construction contractors, including subcontractors and suppliers...

48 CFR 36.303-1 - Phase One.

Code of Federal Regulations, 2011 CFR

2011-10-01

... OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Two-Phase Design-Build Selection... competence; (B) Capability to perform; (C) Past performance of the offeror's team (including the architect... purposes and objectives of two-phase design-build contracting). (b) After evaluating phase-one proposals...

48 CFR 36.303-1 - Phase One.

Code of Federal Regulations, 2013 CFR

2013-10-01

... OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Two-Phase Design-Build Selection... competence; (B) Capability to perform; (C) Past performance of the offeror's team (including the architect... purposes and objectives of two-phase design-build contracting). (b) After evaluating phase-one proposals...

48 CFR 36.303-1 - Phase One.

Code of Federal Regulations, 2010 CFR

2010-10-01

... OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Two-Phase Design-Build Selection... competence; (B) Capability to perform; (C) Past performance of the offeror's team (including the architect... purposes and objectives of two-phase design-build contracting). (b) After evaluating phase-one proposals...

48 CFR 36.303-1 - Phase One.

Code of Federal Regulations, 2012 CFR

2012-10-01

... OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Two-Phase Design-Build Selection... competence; (B) Capability to perform; (C) Past performance of the offeror's team (including the architect... purposes and objectives of two-phase design-build contracting). (b) After evaluating phase-one proposals...

48 CFR 36.303-1 - Phase One.

Code of Federal Regulations, 2014 CFR

2014-10-01

... OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Two-Phase Design-Build Selection... competence; (B) Capability to perform; (C) Past performance of the offeror's team (including the architect... purposes and objectives of two-phase design-build contracting). (b) After evaluating phase-one proposals...

48 CFR 39.002 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY 39.002 Definitions. As used in this part— Modular contracting means use of one or more contracts to acquire information technology systems in successive... technology, means that the information technology accurately processes date/time data (including, but not...

36 CFR 330.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the contract law enforcement program including preparation of and management of contracts ensuing from... Parks, Forests, and Public Property CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY REGULATION OF LAW ENFORCEMENT SERVICES CONTRACTS AT CIVIL WORKS WATER RESOURCE PROJECTS ADMINISTERED BY THE CHIEF OF ENGINEERS...

48 CFR 736.602-3 - Evaluation board functions.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... 736.602-3 Section 736.602-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer... of the contracting activity for his/her approval. This selection memorandum shall include the...

48 CFR 736.602-3 - Evaluation board functions.

Code of Federal Regulations, 2011 CFR

2011-10-01

.... 736.602-3 Section 736.602-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer... of the contracting activity for his/her approval. This selection memorandum shall include the...

Why do employees worry about their jobs? A meta-analytic review of predictors of job insecurity.

PubMed

Keim, Alaina C; Landis, Ronald S; Pierce, Charles A; Earnest, David R

2014-07-01

We used psychological contract theory as a framework to meta-analytically review subjective and objective predictors of employees' perceived job insecurity. Seventy-six samples from 68 studies were included in our review. Results revealed that lower levels of job insecurity are associated with having an internal locus of control, lower amounts of role ambiguity and role conflict, greater amounts of organizational communication, less organizational change, younger employees, and white-collar and permanent work. Moderator analyses further revealed that relations between job insecurity and age, gender, education, and formal contracts are moderated by unemployment rates, countries of origin, and type of job insecurity measure. We discuss theoretical and practical implications for psychological contract theory and occupational health, and offer directions for future research.

Synaptic activity-related classical protein kinase C isoform localization in the adult rat neuromuscular synapse.

PubMed

Besalduch, Núria; Tomàs, Marta; Santafé, Manel M; Garcia, Neus; Tomàs, Josep; Lanuza, Maria Angel

2010-01-10

Protein kinase C (PKC) is essential for signal transduction in a variety of cells, including neurons and myocytes, and is involved in both acetylcholine release and muscle fiber contraction. Here, we demonstrate that the increases in synaptic activity by nerve stimulation couple PKC to transmitter release in the rat neuromuscular junction and increase the level of alpha, betaI, and betaII isoforms in the membrane when muscle contraction follows the stimulation. The phosphorylation activity of these classical PKCs also increases. It seems that the muscle has to contract in order to maintain or increase classical PKCs in the membrane. We use immunohistochemistry to show that PKCalpha and PKCbetaI were located in the nerve terminals, whereas PKCalpha and PKCbetaII were located in the postsynaptic and the Schwann cells. Stimulation and contraction do not change these cellular distributions, but our results show that the localization of classical PKC isoforms in the membrane is affected by synaptic activity.

CRRES experiments, data collection, analysis and publication

NASA Technical Reports Server (NTRS)

Miller, George P.

1992-01-01

The tasks undertaken to be performed under this contract included the continued coordination and documentation of the CRRES program and the development of an archive that details the experimental results obtained by the CRRES Program. Details of the work undertaken and results achieved are summarized in the following sections.

Tort Liability.

ERIC Educational Resources Information Center

Delon, Floyd G.

Although the definition has its limitations, a tort is generally defined as a civil wrong, excluding breach of contract, that results in injury to another. Torts include both intentional and unintentional acts, and the resulting injuries may range from actual physical harm to damage to the individual's tangible or intangible property. If it is…

48 CFR 217.7401 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... are not agreed upon before performance is begun under the action. Examples are letter contracts... OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Undefinitized Contract Actions 217.7401 Definitions. As used in this subpart— (a) Contract action means an action which results...

Inhibition of agonist-induced smooth muscle contraction by picotamide in the male human lower urinary tract outflow region.

PubMed

Hennenberg, Martin; Tamalunas, Alexander; Wang, Yiming; Keller, Patrick; Schott, Melanie; Strittmatter, Frank; Herlemann, Annika; Yu, Qingfeng; Rutz, Beata; Ciotkowska, Anna; Stief, Christian G; Gratzke, Christian

2017-05-15

Male lower urinary tract symptoms (LUTS) due to bladder outlet obstruction are characterized by abnormal smooth muscle contractions in the lower urinary tract. Alpha 1 -adrenoceptor antagonists may induce smooth muscle relaxation in the outflow region and represent the current gold standard of medical treatment. However, results may be unsatisfactory or inadequate. Apart from α 1 -adrenoceptor agonists, smooth muscle contraction in the outflow region may be induced by thromboxane A 2 (TXA 2 ), endothelins, or muscarinic receptor agonists. Here, we studied effects of the thromboxane A 2 receptor (TP receptor) antagonist picotamide on contraction in the human male bladder trigone and prostate. Carbachol, the α 1 -adrenoceptor agonist phenylephrine, the thromboxane A 2 analog U46619, and electric field stimulation (EFS) induced concentration- or frequency-dependent contractions of trigone tissues in an organ bath. Picotamide (300µM) inhibited carbachol-, phenylephrine-, U46619-, and EFS-induced contractions. Endothelins 1-3 induced concentration-dependent contractions of prostate tissues, which were inhibited by picotamide. Analyses using real time polymerase chain reaction and antibodies suggested expression of thromboxane A 2 receptors and synthase in trigone smooth muscle cells. Thromboxane B 2 (the stable metabolite of thromboxane A 2 ) was detectable by enzyme immune assay in trigone samples, with most values ranging between 50 and 150pg/mg trigone protein. Picotamide inhibits contractions induced by different stimuli in the human lower urinary tract, including cholinergic, adrenergic, thromboxane A 2 - and endothelin-induced, and neurogenic contractions in different locations of the outflow region. This distinguishes picotamide from current medical treatments for LUTS, and suggests that picotamide may induce urodynamic effects in vivo. Copyright © 2017. Published by Elsevier B.V.

78 FR 54687 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... Service filing seeking to include a new International Business Reply Service (IBRS) agreement within the... Postal Service seeks to include a new International Business Reply Service (IBRS) agreement (Agreement... a Functionally Equivalent International Business Reply Service Competitive Contract 3 Negotiated...

Risk factors for injury among construction workers at Denver International Airport.

PubMed

Lowery, J T; Borgerding, J A; Zhen, B; Glazner, J E; Bondy, J; Kreiss, K

1998-08-01

The Denver International Airport construction project provided a rare opportunity to identify risk factors for injury on a large construction project for which 769 contractors were hired to complete 2,843 construction contracts. Workers' compensation claims and payroll data for individual contracts were recorded in an administrative database developed by the project's Owner-Controlled Insurance Program. From claims andy payroll data linked with employee demographic information, we calculated injury rates per 200,000 person-hours by contract and over contract characteristics of interest. We used Poisson regression models to examine contract-specific risk factors in relation to total injuries, lost-work-time (LWT), and non-LWT injuries. We included contract-specific expected loss rates (ELRs) in the model to control for prevailing risk of work and used logistic regression methods to determine the association between LWT and non-LWT injuries on contracts. Injury rates were highest during the first year of construction, at the beginning of contracts, and among older workers. Risk for total and non-LWT injuries was elevated for building construction contracts, contract for special trades companies (SIC 17), contracts with payrolls over $1 million, and those with overtime payrolls greater than 20%. Risk for LWT injuries only was increased for site development contracts and contract starting in the first year of construction. Contracts experiencing one or more minor injuries were four times as likely to have at least one major injury (OR = 4.0, 95% CI (2.9, 5.5)). Enhancement of DIA's safety infrastructure during the second year of construction appears to have been effective in reducing serious (LWT) injures. The absence of correlation between injury rates among contracts belonging to the same company suggest that targeting of safety resources at the level of the contract may be an effective approach to injury prevention. Interventions focused on high-risk contracts, including those with considerable overtime work, contracts held by special trades contractors (SIC 17), and contracts belonging to small and mid-sized companies, and on high-risk workers, such as those new to a construction site or new to a contract may reduce injury burden on large construction sites. The join occurrence of minor and major injuries on a contract level suggests that surveillance of minor injuries may be useful in identifying opportunities for prevention of major injures.

48 CFR 846.302-71 - Inspection.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Inspection. 846.302-71 Section 846.302-71 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 846.302-71 Inspection. The contracting officer shall include a...

48 CFR 243.204-70-7 - Plans and reports.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 243.204-70-7 Plans and reports. To provide for enhanced management and oversight of unpriced change orders, departments and agencies shall— (a) Include in the Consolidated Undefinitized Contract Action (UCA) Management...

48 CFR 37.101 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... CONTRACTING SERVICE CONTRACTING Service Contracts-General 37.101 Definitions. As used in this part— Child care services means child protective services (including the investigation of child abuse and neglect reports), social services, health and mental health care, child (day) care, education (whether or not directly...

48 CFR 37.101 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CONTRACTING SERVICE CONTRACTING Service Contracts-General 37.101 Definitions. As used in this part— Child care services means child protective services (including the investigation of child abuse and neglect reports), social services, health and mental health care, child (day) care, education (whether or not directly...

48 CFR 37.101 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... CONTRACTING SERVICE CONTRACTING Service Contracts-General 37.101 Definitions. As used in this part— Child care services means child protective services (including the investigation of child abuse and neglect reports), social services, health and mental health care, child (day) care, education (whether or not directly...

Whither Performance Contracting?

ERIC Educational Resources Information Center

Green, Norman S.

This report describes briefly performance contracts; discusses their shortcomings, pitfalls, and advantages; and gives some insight into the future development of this new concept. Two shortcomings of performance contracting include (1) teaching to the test and (2) board abdication of its responsibility for making final decisions about educational…

48 CFR 752.7004 - Emergency locator information.

Code of Federal Regulations, 2010 CFR

2010-10-01

... information. 752.7004 Section 752.7004 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of USAID Contract Clauses 752.7004 Emergency locator information. The following clause is to be included in all contracts requiring...

48 CFR 752.7004 - Emergency locator information.

Code of Federal Regulations, 2011 CFR

2011-10-01

... information. 752.7004 Section 752.7004 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of USAID Contract Clauses 752.7004 Emergency locator information. The following clause is to be included in all contracts requiring...

77 FR 4880 - Revision of Form FHWA-1273

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-31

...] Revision of Form FHWA-1273 AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice; request for comments. SUMMARY: The FHWA is requesting comments on a proposed revision of form FHWA-1273--``Required Contract Provisions Federal-Aid Construction Contracts.'' This form includes certain contract provisions...

LANDSAT-D investigations in snow hydrology

NASA Technical Reports Server (NTRS)

Dozier, J. (Principal Investigator); Davis, R. E.; Dubayah, R. O.; Frew, J. E.; Li, S.; Marks, D.; Milliff, R. F.; Rousseau, D. D.; Wan, Z. M.

1985-01-01

Work undertaken during the contract and its results are described. Many of the results from this investigation are available in journal or conference proceedings literature - published, accepted for publication, or submitted for publication. For these the reference and the abstract are given. Those results that have not yet been submitted separately for publication are described in detail. Accomplishments during the contract period are summarized as follows: (1) analysis of the snow reflectance characteristics of the LANDSAT Thematic Mapper, including spectral suitability, dynamic range, and spectral resolution; (2) development of a variety of atmospheric models for use with LANDSAT Thematic Mapper data. These include a simple but fast two-stream approximation for inhomogeneous atmospheres over irregular surfaces, and a doubling model for calculation of the angular distribution of spectral radiance at any level in an plane-parallel atmosphere; (3) incorporation of digital elevation data into the atmospheric models and into the analysis of the satellite data; and (4) textural analysis of the spatial distribution of snow cover.

Pier and contraction scour prediction in cohesive soils at selected bridges in Illinois

USGS Publications Warehouse

Straub, Timothy D.; Over, Thomas M.

2010-01-01

This report presents the results of testing the Scour Rate In Cohesive Soils-Erosion Function Apparatus (SRICOS-EFA) method for estimating scour depth of cohesive soils at 15 bridges in Illinois. The SRICOS-EFA method for complex pier and contraction scour in cohesive soils has two primary components. The first component includes the calculation of the maximum contraction and pier scour (Zmax). The second component is an integrated approach that considers a time factor, soil properties, and continued interaction between the contraction and pier scour (SRICOS runs). The SRICOS-EFA results were compared to scour prediction results for non-cohesive soils based on Hydraulic Engineering Circular No. 18 (HEC-18). On average, the HEC-18 method predicted higher scour depths than the SRICOS-EFA method. A reduction factor was determined for each HEC-18 result to make it match the maximum of three types of SRICOS run results. The unconfined compressive strength (Qu) for the soil was then matched with the reduction factor and the results were ranked in order of increasing Qu. Reduction factors were then grouped by Qu and applied to each bridge site and soil. These results, and comparison with the SRICOS Zmax calculation, show that less than half of the reduction-factor method values were the lowest estimate of scour; whereas, the Zmax method values were the lowest estimate for over half. A tiered approach to predicting pier and contraction scour was developed. There are four levels to this approach numbered in order of complexity, with the fourth level being a full SRICOS-EFA analysis. Levels 1 and 2 involve the reduction factors and Zmax calculation, and can be completed without EFA data. Level 3 requires some surrogate EFA data. Levels 3 and 4 require streamflow for input into SRICOS. Estimation techniques for both EFA surrogate data and streamflow data were developed.

Characteristics of power spectrum density function of EMG during muscle contraction below 30%MVC.

PubMed

Roman-Liu, Danuta; Konarska, Maria

2009-10-01

The aim of the study was to quantify changes in PSDF frequency bands of the EMG signal and EMG parameters such as MF, MPF and zero crossing, with an increase in the level of muscle contractions in the range from 0.5% to 30% RMS(max) and to determine the frequency bands with the lowest dependency on RMS level so that this could be used in investigating muscle fatigue. Sixteen men, aged from 23 to 33 years old (mean 26.1), who participated in the study performed two force exertion tests. Fragments of EMG which corresponded to the levels of muscle contraction of 0.5%, 1%, 2.5%, 5%, 10%, 15%, 20%, 25%, 30% RMS(max) registered from left and right trapezius pars descendents (TP) and left and right extensor digitorum superficialis (ED) muscles were selected for analysis. The analysis included changes in standard parameters of the EMG signal and changes in PSDF frequency bands, which occurred across muscle contraction levels. To analyze changes in PSDF across the level of muscle contraction, the spectrum was divided into six frequency bandwidths. The analysis of parameters focused on the differences in those parameters between the analyzed muscles, at different levels of muscle contraction. The study revealed that, at muscle contraction levels below 5% RMSmax, contraction level influences standard parameters of the EMG signal and that at such levels of muscle contraction every change in muscle contraction level (recruitment of additional MUs) is reflected in PSDF. The frequency band with the lowest dependency on contraction level was 76-140 Hz for which in both muscles no contraction level effect was detected for contraction levels above 5% RMS(max). The reproducibility of the results was very high, since the observations in of the left and right muscles were almost equal. The other factor, which strongly influences PSDF of the EMG signal, is probably the examined muscle structure (muscle morphology, size, function, subcutaneous layer, cross talk). It seems that low frequency bands up to 25 Hz are especially feasible for type of muscle.

Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels.

PubMed

Kobayashi, Tetsu; Kim, HuiJung; Liu, Xiangde; Sugiura, Hisatoshi; Kohyama, Tadashi; Fang, Qiuhong; Wen, Fu-Qiang; Abe, Shinji; Wang, Xingqi; Atkinson, Jeffrey J; Shipley, James M; Senior, Robert M; Rennard, Stephen I

2014-06-01

Matrix metalloproteinase-9 (MMP-9) is a matrix-degrading enzyme implicated in many biological processes, including inflammation. It is produced by many cells, including fibroblasts. When cultured in three-dimensional (3D) collagen gels, fibroblasts contract the surrounding matrix, a function that is thought to model the contraction that characterizes both normal wound repair and fibrosis. The current study was designed to evaluate the role of endogenously produced MMP-9 in fibroblast contraction of 3D collagen gels. Fibroblasts from mice lacking expression of MMP-9 and human lung fibroblasts (HFL-1) transfected with MMP-9 small-interfering RNA (siRNA) were used. Fibroblasts were cast into type I collagen gels and floated in culture medium with or without transforming growth factor (TGF)-β1 for 5 days. Gel size was determined daily using an image analysis system. Gels made from MMP-9 siRNA-treated human fibroblasts contracted less than control fibroblasts, as did fibroblasts incubated with a nonspecific MMP inhibitor. Similarly, fibroblasts cultured from MMP-9-deficient mice contracted gels less than did fibroblasts from control mice. Transfection of the MMP-9-deficient murine fibroblasts with a vector expressing murine MMP-9 restored contractile activity to MMP-9-deficient fibroblasts. Inhibition of MMP-9 reduced active TGF-β1 and reduced several TGF-β1-driven responses, including activity of a Smad3 reporter gene and production of fibronectin. Because TGF-β1 also drives fibroblast gel contraction, this suggests the mechanism for MMP-9 regulation of contraction is through the generation of active TGF-β1. This study provides direct evidence that endogenously produced MMP-9 has a role in regulation of tissue contraction of 3D collagen gels mediated by fibroblasts. Copyright © 2014 the American Physiological Society.

Introduction to Acquisition Management.

DTIC Science & Technology

1987-12-01

reported to the SECDEF and the Defense Acquisition Executive. During this phase (the third of the life cycle), the systera, including all essential...will not be enough. R&M 2000 is a those military and civilian maintenance people cultural change within the Air Force and what they find frustrating or...Contracting Officer position. Respon- sibilities of contracting officers are divided : kud thne-phased; the contract is awarded by the Procuring Contracting

REACTIVE OXYGEN SPECIES: IMPACT ON SKELETAL MUSCLE

PubMed Central

Powers, Scott K.; Ji, Li Li; Kavazis, Andreas N.; Jackson, Malcolm J.

2014-01-01

It is well established that contracting muscles produce both reactive oxygen and nitrogen species. Although the sources of oxidant production during exercise continue to be debated, growing evidence suggests that mitochondria are not the dominant source. Regardless of the sources of oxidants in contracting muscles, intense and prolonged exercise can result in oxidative damage to both proteins and lipids in the contracting myocytes. Further, oxidants regulate numerous cell signaling pathways and modulate the expression of many genes. This oxidant-mediated change in gene expression involves changes at transcriptional, mRNA stability, and signal transduction levels. Furthermore, numerous products associated with oxidant-modulated genes have been identified and include antioxidant enzymes, stress proteins, and mitochondrial electron transport proteins. Interestingly, low and physiological levels of reactive oxygen species are required for normal force production in skeletal muscle, but high levels of reactive oxygen species result in contractile dysfunction and fatigue. Ongoing research continues to explore the redox-sensitive targets in muscle that are responsible for both redox-regulation of muscle adaptation and oxidant-mediated muscle fatigue. PMID:23737208

7 CFR 1466.21 - Contract requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... environmental significance that include methane digesters, other innovative technologies, and projects that will... practices, consistent with the provisions of § 1466.25; (iv) Implement a comprehensive nutrient management plan when the EQIP contract includes an animal waste management facility; (v) Implement a forest...

48 CFR 16.102 - Policies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Policies. 16.102 Section... CONTRACT TYPES TYPES OF CONTRACTS Selecting Contract Types 16.102 Policies. (a) Contracts resulting from sealed bidding shall be firm-fixed-price contracts or fixed-price contracts with economic price...

23 CFR 172.9 - Approvals.

Code of Federal Regulations, 2010 CFR

2010-04-01

... coordination of services, may be reasonably liable for costs resulting from errors or deficiencies in design furnished under its contract. (b) Contracts. Contracts and contract settlements involving design services... of a contract or settlement of a contract for design services for a project that is expected to fall...

[The state of the psychological contract and its relation with employees' psychological health].

PubMed

Gracia, Francisco Javier; Silla, Inmaculada; Peiró, José María; Fortes-Ferreira, Lina

2006-05-01

In the present paper the role of the state of the psychological contract to predict psychological health results is studied in a sample of 385 employees of different Spanish companies. Results indicate that the state of the psychological contract significantly predicts life satisfaction, work-family conflict and well-being beyond the prediction produced by the content of the psychological contract. In addition, trust and fairness, two dimensions of the state of psychological contract, all together contribute to explain these psychological health variables adding value to the role as predictor of fulfillment of the psychological contract. The results support the approach argued by Guest and colleagues.

48 CFR 970.2672-3 - Contract clause.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Under Section 3161 of the National Defense Authorization Act for Fiscal Year 1993, in contracts for the management and operation of Department of Energy Defense Nuclear Facilities and, as appropriate, in other contracts that include site management responsibilities at a Department of Energy Defense Nuclear Facility...

48 CFR 970.2672-3 - Contract clause.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Under Section 3161 of the National Defense Authorization Act for Fiscal Year 1993, in contracts for the management and operation of Department of Energy Defense Nuclear Facilities and, as appropriate, in other contracts that include site management responsibilities at a Department of Energy Defense Nuclear Facility...

48 CFR 970.2672-3 - Contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Under Section 3161 of the National Defense Authorization Act for Fiscal Year 1993, in contracts for the management and operation of Department of Energy Defense Nuclear Facilities and, as appropriate, in other contracts that include site management responsibilities at a Department of Energy Defense Nuclear Facility...

48 CFR 970.2672-3 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Under Section 3161 of the National Defense Authorization Act for Fiscal Year 1993, in contracts for the management and operation of Department of Energy Defense Nuclear Facilities and, as appropriate, in other contracts that include site management responsibilities at a Department of Energy Defense Nuclear Facility...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 2011.104-70 - NRC Clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Technical Reports, when deliverables include a technical report. (b) The contracting officer shall insert the clause at 2052.211-71 Technical Progress Report, in all solicitations and contracts except— (1...) The contracting officer shall insert the clause at 2052.211-72 Financial Status Report, in applicable...

48 CFR 3416.702 - Basic agreements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Basic agreements. 3416.702... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Agreements 3416.702 Basic agreements. (a)-(d) [Reserved] (e) Negotiated overhead rates. Basic agreements may include negotiated overhead rates for cost...

48 CFR 942.270-1 - Contracting Officer's Representatives.

Code of Federal Regulations, 2010 CFR

2010-10-01

... performing certain technical functions in administering a contract. These functions include, but are not limited to, technical monitoring, inspection, approval of shop drawings, testing, and approval of samples. The COR acts solely as a technical representative of the contracting officer and is not authorized to...

48 CFR 15.605 - Content of unsolicited proposals.

Code of Federal Regulations, 2010 CFR

2010-10-01

... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 15.605 Content of... and type of organization; e.g., profit, nonprofit, educational, small business; (2) Names and..., including alternates; and (4) Type of support needed from the agency; e.g., Government property or personnel...

The Law of Contract and the Private School.

ERIC Educational Resources Information Center

Duncan, Deirdre J.; Duncan, Robyn M.

1986-01-01

Explores contract law governing relationships between the student and school authorities, the teacher and the school, and the school and third parties in Australian private schools. Shows that government schools do not meet the conditions for enforceable contracts under Australian law. Includes seven references. (MLH)

High School Credit by Contract: Correspondence Study.

ERIC Educational Resources Information Center

Alaska State Dept. of Education, Juneau.

A series of fifteen correspondence studies for high school credit by contract are presented. Contracts are included for boating skills and seamanship; boatbuilding; food and food preparation; gardening; livestock raising; salmon aquaculture; sewing, knitting, and needlework; small engine repair; taxidermy and tanning; trapping; training animals;…

76 FR 61985 - Fishing Capacity Reduction Program for the Southeast Alaska Purse Seine Salmon Fishery

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-06

... last few years, many factors are influencing the rising prices including higher catch levels of pink... Relinquishment Contract will result in irreparable damage to the SRA and other Permit Holders. Therefore, money...

Level II scour analysis for Bridge 8 (BARTTH00020008) on Town Highway 2, crossing Roaring Brook, Barton, Vermont

USGS Publications Warehouse

Boehmler, Erick M.; Ivanoff, Michael A.

1996-01-01

Total scour at a highway crossing is comprised of three components: 1) long-term aggradation or degradation; 2) contraction scour (due to reduction in flow area caused by a bridge) and; 3) local scour (caused by accelerated flow around piers and abutments). Total scour is the sum of the three components. Equations are available to compute scour depths for contraction and local scour and a summary of the results follows. Contraction scour for all modelled flows ranged from 1.4 to 2.8 feet and the worst-case contraction scour occurred at the 500-year discharge. Abutment scour ranged from 8.5 to 16.5 feet and the worst-case abutment scour occurred at the 500-year discharge. Additional information on scour depths and depths to armoring are included in the section titled “Scour Results”. Scoured-streambed elevations, based on the calculated scour depths, are presented in tables 1 and 2. A cross-section of the scour computed at the bridge is presented in figure 8. Scour depths were calculated assuming an infinite depth of erosive material and a homogeneous particle-size distribution. It is generally accepted that the Froehlich equation (abutment scour) gives “excessively conservative estimates of scour depths” (Richardson and others, 1995, p. 47). Usually, computed scour depths are evaluated in combination with other information including (but not limited to) historical performance during flood events, the geomorphic stability assessment, existing scour protection measures, and the results of the hydraulic analyses. Therefore, scour depths adopted by VTAOT may differ from the computed values documented herein.

Level II scour analysis for Bridge 4 (CRAFTH00040004) on Town Highway 4, crossing Whitney Brook, Craftsbury, Vermont

USGS Publications Warehouse

Boehmler, Erick M.; Hammond, Robert E.

1996-01-01

Total scour at a highway crossing is comprised of three components: 1) long-term degradation; 2) contraction scour (due to accelerated flow caused by reduction in flow area at a bridge) and; 3) local scour (caused by accelerated flow around piers and abutments). Total scour is the sum of the three components. Equations are available to compute depths for contraction and local scour and a summary of the computed scour results follow. Contraction scour for all modelled flows ranged from 0.7 to 1.7 feet. The worst-case contraction scour occurred at the 500-year discharge. Abutment scour ranged from 10.7 to 15.3 feet. The worst-case abutment scour also occurred at the 500-year discharge. Additional information on scour depths and depths to armoring are included in the section titled “Scour Results”. Scoured-streambed elevations, based on the calculated scour depths, are presented in tables 1 and 2. A cross-section of the scour computed at the bridge is presented in figure 8. Scour depths were calculated assuming an infinite depth of erosive material and a homogeneous particle-size distribution. It is generally accepted that the Froehlich equation (abutment scour) gives “excessively conservative estimates of scour depths” (Richardson and others, 1995, p. 47). Usually, computed scour depths are evaluated in combination with other information including (but not limited to) historical performance during flood events, the geomorphic stability assessment, existing scour protection measures, and the results of the hydraulic analyses. Therefore, scour depths adopted by VTAOT may differ from the computed values documented herein.

The proximal gastric corpus is the most responsive site of motilin-induced contractions in the stomach of the Asian house shrew.

PubMed

Dudani, Amrita; Aizawa, Sayaka; Zhi, Gong; Tanaka, Toru; Jogahara, Takamichi; Sakata, Ichiro; Sakai, Takafumi

2016-07-01

The migrating motor complex (MMC) is responsible for emptying the stomach during the interdigestive period, in preparation for the next meal. It is known that gastric phase III of MMC starts from the proximal stomach and propagates the contraction downwards. We hypothesized that a certain region of the stomach must be more responsive to motilin than others, and that motilin-induced strong gastric contractions propagate from that site. Stomachs of the Suncus or Asian house shrew, a small insectivorous mammal, were dissected and the fundus, proximal corpus, distal corpus, and antrum were examined to study the effect of motilin using an organ bath experiment. Motilin-induced contractions differed in different parts of the stomach. Only the proximal corpus induced gastric contraction even at motilin 10(-10) M, and strong contraction was induced by motilin 10(-9) M in all parts of the stomach. The GPR38 mRNA expression was also higher in the proximal corpus than in the other sections, and the lowest expression was observed in the antrum. GPR38 mRNA expression varied with low expression in the mucosal layer and high expression in the muscle layer. Additionally, motilin-induced contractions in each dissected part of the stomach were inhibited by tetrodotoxin and atropine pretreatment. These results suggest that motilin reactivity is not consistent throughout the stomach, and an area of the proximal corpus including the cardia is the most sensitive to motilin.

Advanced Radioisotope Power Conversion Technology Research and Development

NASA Technical Reports Server (NTRS)

Wong, Wayne A.

2004-01-01

NASA's Radioisotope Power Conversion Technology program is developing next generation power conversion technologies that will enable future missions that have requirements that cannot be met by either the ubiquitous photovoltaic systems or by current Radioisotope Power System (RPS) technology. Performance goals of advanced radioisotope power systems include improvement over the state-of-practice General Purpose Heat Source/Radioisotope Thermoelectric Generator by providing significantly higher efficiency to reduce the number of radioisotope fuel modules, and increase specific power (watts/kilogram). Other Advanced RPS goals include safety, long-life, reliability, scalability, multi-mission capability, resistance to radiation, and minimal interference with the scientific payload. NASA has awarded ten contracts in the technology areas of Brayton, Stirling, Thermoelectric, and Thermophotovoltaic power conversion including five development contracts that deal with more mature technologies and five research contracts. The Advanced RPS Systems Assessment Team includes members from NASA GRC, JPL, DOE and Orbital Sciences whose function is to review the technologies being developed under the ten Radioisotope Power Conversion Technology contracts and assess their relevance to NASA's future missions. Presented is an overview of the ten radioisotope power conversion technology contracts and NASA's Advanced RPS Systems Assessment Team.

48 CFR 1552.211-73 - Level of effort-cost-reimbursement term contract.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracts without fee, cost-sharing contracts, cost-plus-fixed-fee (CPFF) contracts, cost-plus-incentive-fee contracts (CPIF), and cost-plus-award-fee contracts (CPAF). Level of Effort—Cost-Reimbursement Term Contract... additional effort shall not result in any increase in the fixed fee, if any. If this is a cost-plus-incentive...

48 CFR 728.309 - Contract clause for worker's compensation insurance.

Code of Federal Regulations, 2011 CFR

2011-10-01

... INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Insurance 728.309 Contract clause... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract clause for worker... resulting in contracts which require worker's compensation insurance, USAID has contracted with an insurance...

48 CFR 728.309 - Contract clause for worker's compensation insurance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Insurance 728.309 Contract clause... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clause for worker... resulting in contracts which require worker's compensation insurance, USAID has contracted with an insurance...

Context matters in NGO-government contracting for health service delivery: a case study from Pakistan.

PubMed

Zaidi, Shehla; Mayhew, Susannah H; Cleland, John; Green, Andrew T

2012-10-01

Contracting non-governmental organizations (NGOs) for health service provision is gaining increasing importance in low- and middle-income countries. However, the role of the wider context in influencing the effectiveness of contracting is not well studied and is of relevance given that contracting has produced mixed results so far. This paper applies a policy analysis approach to examine the influence of policy and political factors on contracting origin, design and implementation. Evidence is drawn from a country case study of Pakistan involving extensive NGO contracting for human immunodeficiency virus (HIV) prevention services supported by international donor agencies. A multilevel study was conducted using 84 in-depth interviews, 22 semi-structured interviews, document review and direct observation to examine the national policy design, provincial management of contracting and local contract implementation. There were three main findings. First, contracting origin and implementation was an inherently political process affected by the wider policy context. Although in Pakistan a combination of situational events successfully managed to introduce extensive and sophisticated contracting, it ran into difficulties during implementation due to ownership and capacity issues within government. Second, wide-scale contracting was mis-matched with the capacity of local NGOs, which resulted in sub-optimal contract implementation challenging the reliance on market simulation through contracting. Third, we found that contracting can have unintended knock-on effects on both providers and purchasers. As a result of public sector contracts, NGOs became more distanced from their grounded attributes. Effects on government purchasers were more unpredictable, with greater identification with contracting in supportive governance contexts and further distancing in unsupportive contexts. A careful approach is needed in government contracting of NGOs, taking into account acceptance of contracting NGOs, local NGO capacities and potential distancing of NGOs from their traditional attributes under contracts. Political factors and knock-on effects are likely to be heightened in the sudden and aggressive use of contracting in unprepared settings.

48 CFR 352.101-70 - Application of provisions and clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... IDIQ contract, a GWAC, or a BPA, and a purchase order placed under the authority of FAR subpart 13.5... included in the master instrument (e.g., in an IDIQ contract or a BPA), it is not necessary to also include...

48 CFR 352.101-70 - Application of provisions and clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... IDIQ contract, a GWAC, or a BPA, and a purchase order placed under the authority of FAR subpart 13.5... included in the master instrument (e.g., in an IDIQ contract or a BPA), it is not necessary to also include...

48 CFR 352.101-70 - Application of provisions and clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... IDIQ contract, a GWAC, or a BPA, and a purchase order placed under the authority of FAR subpart 13.5... included in the master instrument (e.g., in an IDIQ contract or a BPA), it is not necessary to also include...

48 CFR 352.101-70 - Application of provisions and clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... IDIQ contract, a GWAC, or a BPA, and a purchase order placed under the authority of FAR subpart 13.5... included in the master instrument (e.g., in an IDIQ contract or a BPA), it is not necessary to also include...

48 CFR 352.101-70 - Application of provisions and clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... IDIQ contract, a GWAC, or a BPA, and a purchase order placed under the authority of FAR subpart 13.5... included in the master instrument (e.g., in an IDIQ contract or a BPA), it is not necessary to also include...

48 CFR 22.101-2 - Contract pricing and administration.

Code of Federal Regulations, 2010 CFR

2010-10-01

...-reimbursement contracts or for recognition of costs in pricing fixed-price contracts if they result in... organizations to settle disputes. (c) Strikes normally result in changing patterns of cost incurrence and... recognition of costs in pricing fixed-price contracts. Certain costs may increase because of strikes; e.g...

48 CFR 22.101-2 - Contract pricing and administration.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-reimbursement contracts or for recognition of costs in pricing fixed-price contracts if they result in... organizations to settle disputes. (c) Strikes normally result in changing patterns of cost incurrence and... recognition of costs in pricing fixed-price contracts. Certain costs may increase because of strikes; e.g...

48 CFR 1452.237-71 - Utilization of Woody Biomass.

Code of Federal Regulations, 2011 CFR

2011-10-01

... timber/vegetative sales contract. Payment under the timber/vegetative sales contract must be at a price... appropriate payment specified in the related timber/vegetative sales contract before removal may be authorized... sales notice and/or prospectus, including volume estimates, appraised value and any appropriate special...

22 CFR 1006.220 - Are any procurement contracts included as covered transactions?

Code of Federal Regulations, 2010 CFR

2010-04-01

... covered transactions? 1006.220 Section 1006.220 Foreign Relations INTER-AMERICAN FOUNDATION GOVERNMENTWIDE... the consent of a(n) Inter-American Foundation official. In that case, the contract, regardless of the... appendix to this part. (3) The contract is for federally-required audit services. ...

48 CFR 203.1004 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... OF DEFENSE GENERAL IMPROPER BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contractor Code of Business Ethics and Conduct 203.1004 Contract clauses. (a) Use the clause at 252.203-7003 in solicitations and contracts that include the FAR clause 52.203-13, Contractor Code of Business Ethics and Conduct...

48 CFR 227.7107-1 - Architectural designs and data clauses for architect-engineer or construction contracts.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Government, in solicitations and contracts. (c) The Government shall obtain unlimited rights in shop drawings for construction. In solicitations and contracts calling for delivery of shop drawings, include the clause at 252.227-7033, Rights in Shop Drawings. ...

48 CFR 227.7107-1 - Architectural designs and data clauses for architect-engineer or construction contracts.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Government, in solicitations and contracts. (c) The Government shall obtain unlimited rights in shop drawings for construction. In solicitations and contracts calling for delivery of shop drawings, include the clause at 252.227-7033, Rights in Shop Drawings. ...

48 CFR 227.7107-1 - Architectural designs and data clauses for architect-engineer or construction contracts.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Government, in solicitations and contracts. (c) The Government shall obtain unlimited rights in shop drawings for construction. In solicitations and contracts calling for delivery of shop drawings, include the clause at 252.227-7033, Rights in Shop Drawings. ...

48 CFR 227.7107-1 - Architectural designs and data clauses for architect-engineer or construction contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Government, in solicitations and contracts. (c) The Government shall obtain unlimited rights in shop drawings for construction. In solicitations and contracts calling for delivery of shop drawings, include the clause at 252.227-7033, Rights in Shop Drawings. ...

48 CFR 227.7107-1 - Architectural designs and data clauses for architect-engineer or construction contracts.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Government, in solicitations and contracts. (c) The Government shall obtain unlimited rights in shop drawings for construction. In solicitations and contracts calling for delivery of shop drawings, include the clause at 252.227-7033, Rights in Shop Drawings. ...

40 CFR Appendix to Part 30 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-07-01

... NON-PROFIT ORGANIZATIONS Pt. 30, App. Appendix to Part 30—Contract Provisions All contracts awarded by a recipient, including small purchases, shall contain the following provisions as applicable: 1... unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of supplies or materials...

48 CFR 251.205 - Contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Fleet Management System (IFMS) Vehicles 251.205 Contract clause. Use the clause at 252.251-7001, Use of Interagency Fleet Management System (IFMS)Vehicles and Related Services, in solicitations and contracts which include the clause at FAR 52.251-2, Interagency Fleet Management System (IFMS) Vehicles and Related...

Career Stage and Generational Differences in Psychological Contracts

ERIC Educational Resources Information Center

Hess, Narelle; Jepsen, Denise M.

2009-01-01

Purpose: The purpose of this paper is to determine how employees in different generational groups (or cohorts) and different career stages perceive their psychological contracts. Design/methodology/approach: A survey of 345 working adults included psychological contract obligations, incentives and importance and the cognitive responses of job…

48 CFR 970.3270 - Standard financial management clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... management and operating contracts with integrated accounting systems. (iv) The contracting officer shall... accounting systems. (2) 970.5232-3, Accounts, records, and inspection. If the contract includes the clause at... systems: (1) 970.5232-7, Financial management system. (2) 970.5232-8, Integrated accounting. (c) Any...

48 CFR 52.234-1 - Industrial Resources Developed Under Defense Production Act Title III.

Code of Federal Regulations, 2011 CFR

2011-10-01

... materials, services, processes, or manufacturing equipment (including the processes, technologies, and... project contractor for testing and qualification of a Title III industrial resource to the Contracting... Contracting Officer modifies the contract to direct testing pursuant to this clause, the Government will...

26 CFR 1.408-3 - Individual retirement annuities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... merely because it provides for waiver of premium on disability. An individual retirement annuity contract... contract is not a taxable event. Distributions under the contract are includible in gross income in...) Annual premium. Except in the case of a contribution to a simplified employee pension described in...

75 FR 880 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-06

...: January 6, 2010. ADDRESSES: Submit comments electronically via the Commission's Filing Online system at... financial documentation is included with this filing as a separate Excel file. Id. at 2. \\4\\ The contract at... contract, the present contract ``allows the customer to tender items that meet the requirements for Canada...

Poorly Understood Aspects of Striated Muscle Contraction

PubMed Central

Månsson, Alf

2015-01-01

Muscle contraction results from cyclic interactions between the contractile proteins myosin and actin, driven by the turnover of adenosine triphosphate (ATP). Despite intense studies, several molecular events in the contraction process are poorly understood, including the relationship between force-generation and phosphate-release in the ATP-turnover. Different aspects of the force-generating transition are reflected in the changes in tension development by muscle cells, myofibrils and single molecules upon changes in temperature, altered phosphate concentration, or length perturbations. It has been notoriously difficult to explain all these events within a given theoretical framework and to unequivocally correlate observed events with the atomic structures of the myosin motor. Other incompletely understood issues include the role of the two heads of myosin II and structural changes in the actin filaments as well as the importance of the three-dimensional order. We here review these issues in relation to controversies regarding basic physiological properties of striated muscle. We also briefly consider actomyosin mutation effects in cardiac and skeletal muscle function and the possibility to treat these defects by drugs. PMID:25961006

Poorly understood aspects of striated muscle contraction.

PubMed

Månsson, Alf; Rassier, Dilson; Tsiavaliaris, Georgios

2015-01-01

Muscle contraction results from cyclic interactions between the contractile proteins myosin and actin, driven by the turnover of adenosine triphosphate (ATP). Despite intense studies, several molecular events in the contraction process are poorly understood, including the relationship between force-generation and phosphate-release in the ATP-turnover. Different aspects of the force-generating transition are reflected in the changes in tension development by muscle cells, myofibrils and single molecules upon changes in temperature, altered phosphate concentration, or length perturbations. It has been notoriously difficult to explain all these events within a given theoretical framework and to unequivocally correlate observed events with the atomic structures of the myosin motor. Other incompletely understood issues include the role of the two heads of myosin II and structural changes in the actin filaments as well as the importance of the three-dimensional order. We here review these issues in relation to controversies regarding basic physiological properties of striated muscle. We also briefly consider actomyosin mutation effects in cardiac and skeletal muscle function and the possibility to treat these defects by drugs.

The Joint Effects-Based Contracting Execution System: A Proposed Enabling Concept for Future Joint Expeditionary Contracting Execution

DTIC Science & Technology

2008-12-01

average 1 hour per response, including the time for reviewing instruction, searching existing data sources , gathering and maintaining the data needed...Representative for the Contracting Officer on five contracts whose value xii exceeded $200 million and participated on four source selection committees...roles on source selection boards; Consolidated Husbanding Services for all Pacific Ports, Consolidated MWR services for the Pacific, Software

Contract Incentives for Product Quality

DTIC Science & Technology

1980-06-01

incurred by the contractor, i.e., cost reimbursement contracts. It differs also in that the product may only be definable in general terms, thus...government employees. There are other fiscal motivations as well since if government quality personnel do not accept their system, reimbursement will not... reimbursement contracts in the DAR, Paragraph 3-808.1 as follows: 3-808 Profit, Including Fees Under Cost- Reimbursement Type Contracts 3-808.1 Policy (a

PubMed Central

Baeßler, Kaven; Junginger, Bärbel

2017-01-01

Background The aims of physiotherapy in stress incontinent women are to improve pelvic floor function and the continence mechanism including bladder neck support and urethral closure pressure. In Germany, traditional conservative treatment often includes gymnastic exercises with unclear effects on the bladder neck. The aim of this study was to sonographically assess bladder neck movements during selected exercises. Methods Fifteen healthy, continent women without previous vaginal births, who were able to voluntarily contract their pelvic floor muscels performed the shoulder bridge, the abdominal press, tiptoe and the Pilates clam exercises. The first set was performed without any additional instructions. During the second set directions were given to activate the pelvic floor before beginning each exercise and to maintain the contraction throughout the exercise. Bladder neck movement was measured on perineal ultrasound using a validated method with the pubic symphysis as a reference point. Results The median age of participants was 32 years, median BMI was 23. Eight women were nulliparous and seven had given birth to 1 – 2 children via caesarean section. When exercises were performed without voluntary pelvic floor contraction the bladder neck descended on average between 2.3 and 4.4 mm, and with pelvic floor contraction prior to the exercise only between 0.5 and 2.1 mm (p > 0.05 except for abdominal press p = 0.007). The Pilates clam exercise and toe stand stabilised the bladder neck most effectively. Discussion Bladder neck descent often occurs during pelvic floor gymnastic exercises as traditionally performed in Germany, and a voluntary pelvic floor contraction during the exercises does not necessarily prevent this. PMID:28757655

Contracting out to improve the use of clinical health services and health outcomes in low- and middle-income countries.

PubMed

Odendaal, Willem A; Ward, Kim; Uneke, Jesse; Uro-Chukwu, Henry; Chitama, Dereck; Balakrishna, Yusentha; Kredo, Tamara

2018-04-03

Contracting out of governmental health services is a financing strategy that governs the way in which public sector funds are used to have services delivered by non-governmental health service providers (NGPs). It represents a contract between the government and an NGP, detailing the mechanisms and conditions by which the latter should provide health care on behalf of the government. Contracting out is intended to improve the delivery and use of healthcare services. This Review updates a Cochrane Review first published in 2009. To assess effects of contracting out governmental clinical health services to non-governmental service provider/s, on (i) utilisation of clinical health services; (ii) improvement in population health outcomes; (iii) improvement in equity of utilisation of these services; (iv) costs and cost-effectiveness of delivering the services; and (v) improvement in health systems performance. We searched CENTRAL, MEDLINE, Embase, NHS Economic Evaluation Database, EconLit, ProQuest, and Global Health on 07 April 2017, along with two trials registers - ClinicalTrials.gov and the International Clinical Trials Registry Platform - on 17 November 2017. Individually randomised and cluster-randomised trials, controlled before-after studies, interrupted time series, and repeated measures studies, comparing government-delivered clinical health services versus those contracted out to NGPs, or comparing different models of non-governmental-delivered clinical health services. Two authors independently screened all records, extracted data from the included studies and assessed the risk of bias. We calculated the net effect for all outcomes. A positive value favours the intervention whilst a negative value favours the control. Effect estimates are presented with 95% confidence intervals. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assess the certainty of the evidence and we prepared a Summary of Findings table. We included two studies, a cluster-randomised trial conducted in Cambodia, and a controlled before-after study conducted in Guatemala. Both studies reported that contracting out over 12 months probably makes little or no difference in (i) immunisation uptake of children 12 to 24 months old (moderate-certainty evidence), (ii) the number of women who had more than two antenatal care visits (moderate-certainty evidence), and (iii) female use of contraceptives (moderate-certainty evidence).The Cambodia trial reported that contracting out may make little or no difference in the mortality over 12 months of children younger than one year of age (net effect = -4.3%, intervention effect P = 0.36, clustered standard error (SE) = 3.0%; low-certainty evidence), nor to the incidence of childhood diarrhoea (net effect = -16.2%, intervention effect P = 0.07, clustered SE = 19.0%; low-certainty evidence). The Cambodia study found that contracting out probably reduces individual out-of-pocket spending over 12 months on curative care (net effect = $ -19.25 (2003 USD), intervention effect P = 0.01, clustered SE = $ 5.12; moderate-certainty evidence). The included studies did not report equity in the use of clinical health services and in adverse effects. This update confirms the findings of the original review. Contracting out probably reduces individual out-of-pocket spending on curative care (moderate-certainty evidence), but probably makes little or no difference in other health utilisation or service delivery outcomes (moderate- to low-certainty evidence). Therefore, contracting out programmes may be no better or worse than government-provided services, although additional rigorously designed studies may change this result. The literature provides many examples of contracting out programmes, which implies that this is a feasible response when governments fail to provide good clinical health care. Future contracting out programmes should be framed within a rigorous study design to allow valid and reliable measures of their effects. Such studies should include qualitative research that assesses the views of programme implementers and beneficiaries, and records implementation mechanisms. This approach may reveal enablers for, and barriers to, successful implementation of such programmes.

10 CFR 950.14 - Standby Support Contract: Covered events, exclusions, covered delay and covered cost provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... include a provision setting forth the type of events that are covered events under the contract. The type...) Litigation in State, Federal, local, or tribal courts, including appeals of Commission decisions related to..., including but not limited to the following types of events: (i) The sponsor's failure to comply with...

41 CFR 102-2.105 - What information must agencies include in their follow-up analysis?

Code of Federal Regulations, 2013 CFR

2013-07-01

... agencies include in their follow-up analysis? In your follow-up analysis, provide information that may... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What information must agencies include in their follow-up analysis? 102-2.105 Section 102-2.105 Public Contracts and Property...

41 CFR 102-2.105 - What information must agencies include in their follow-up analysis?

Code of Federal Regulations, 2011 CFR

2011-01-01

... agencies include in their follow-up analysis? In your follow-up analysis, provide information that may... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What information must agencies include in their follow-up analysis? 102-2.105 Section 102-2.105 Public Contracts and Property...

41 CFR 102-2.105 - What information must agencies include in their follow-up analysis?

Code of Federal Regulations, 2010 CFR

2010-07-01

... agencies include in their follow-up analysis? In your follow-up analysis, provide information that may... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What information must agencies include in their follow-up analysis? 102-2.105 Section 102-2.105 Public Contracts and Property...

41 CFR 102-2.105 - What information must agencies include in their follow-up analysis?

Code of Federal Regulations, 2014 CFR

2014-01-01

... agencies include in their follow-up analysis? In your follow-up analysis, provide information that may... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What information must agencies include in their follow-up analysis? 102-2.105 Section 102-2.105 Public Contracts and Property...

41 CFR 102-2.105 - What information must agencies include in their follow-up analysis?

Code of Federal Regulations, 2012 CFR

2012-01-01

... agencies include in their follow-up analysis? In your follow-up analysis, provide information that may... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What information must agencies include in their follow-up analysis? 102-2.105 Section 102-2.105 Public Contracts and Property...

The Principal and Tort Liability.

ERIC Educational Resources Information Center

Stern, Ralph D.

The emphasis of this chapter is on the tort liability of principals, especially their commission of unintentional torts or torts resulting from negligent conduct. A tort is defined as a wrongful act, not including a breach of contract or trust, which results in injury to another's person, property, or reputation and for which the injured party is…

Sensory-motor responses to mechanical stimulation of the esophagus after sensitization with acid

PubMed Central

Drewes, Asbjorn Mohr; Reddy, Hariprasad; Staahl, Camilla; Pedersen, Jan; Funch-Jensen, Peter; Arendt-Nielsen, Lars; Gregersen, Hans

2005-01-01

AIM: Sensitization most likely plays an important role in chronic pain disorders, and such sensitization can be mimicked by experimental acid perfusion of the esophagus. The current study systematically investigated the sensory and motor responses of the esophagus to controlled mechanical stimuli before and after sensitization. METHODS: Thirty healthy subjects were included. Distension of the distal esophagus with a balloon was performed before and after perfusion with 0.1 mol/L hydrochloric acid for 30 min. An impedance planimetry system was used to measure cross-sectional area, volume, pressure, and tension during the distensions. A new model allowed evaluation of the phasic contractions by the tension during contractions as a function of the initial muscle length before the contraction (comparable to the Frank-Starling law for the heart). Length-tension diagrams were used to evaluate the muscle tone before and after relaxation of the smooth muscle with butylscopolamine. RESULTS: The sensitization resulted in allodynia and hyperalgesia to the distension volumes, and the degree of sensitization was related to the infused volume of acid. Furthermore, a nearly 50% increase in the evoked referred pain was seen after sensitization. The mechanical analysis demonstrated hyper-reactivity of the esophagus following acid perfusion, with an increased number and force of the phasic contractions, but the muscle tone did not change. CONCLUSION: Acid perfusion of the esophagus sensitizes the sensory pathways and facilitates secondary contractions. The new model can be used to study abnormal sensory-motor mechanisms in visceral organs. PMID:16038036

The U.S. Public's Investment in Medical Research: An Evolving Social Contract.

PubMed

Heinig, Stephen J; Dev, Anurupa; Bonham, Ann C

2016-01-01

Medical researchers and their institutions are operating under extraordinary financial stress. More than a decade after completion of the 5-year doubling of the National Institutes of Health budget, the medical research community must confront a significant loss in National Institutes of Health purchasing power and downward pressures in federal discretionary spending. In part, this trend results from a federal budget stalemate over the growth in entitlement programs, particularly spending on medical care. This article considers the changing nature of the federal investment in medical research and the potential for medical researchers and institutions conducting the full spectrum of research to improve health system performance and health equity. In our view, continued federal investments reflect an evolving social contract for research serving the public good; the term contract is used metaphorically to represent a figurative, implicit agreement between the scientific community and the public's representatives in government. Under this conceptual contract, the American people--who are ultimately the funders of research, research training and infrastructure--expect outcomes that lead to better health, security or other benefits. The evolving contract includes expectations for more accountability, transparency, sharing of results and resources, and better integration of research systems and cultures that used to take pride in boundaries and distinctions. We outline here some of the major movements of organizations realigning to social support, which are increasingly essential to sustain public investment in medical research. Copyright © 2016 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

Droplet Breakup in Expansion-contraction Microchannels

PubMed Central

Zhu, Pingan; Kong, Tiantian; Lei, Leyan; Tian, Xiaowei; Kang, Zhanxiao; Wang, Liqiu

2016-01-01

We investigate the influences of expansion-contraction microchannels on droplet breakup in capillary microfluidic devices. With variations in channel dimension, local shear stresses at the injection nozzle and focusing orifice vary, significantly impacting flow behavior including droplet breakup locations and breakup modes. We observe transition of droplet breakup location from focusing orifice to injection nozzle, and three distinct types of recently-reported tip-multi-breaking modes. By balancing local shear stresses and interfacial tension effects, we determine the critical condition for breakup location transition, and characterize the tip-multi-breaking mode quantitatively. In addition, we identify the mechanism responsible for the periodic oscillation of inner fluid tip in tip-multi-breaking mode. Our results offer fundamental understanding of two-phase flow behaviors in expansion-contraction microstructures, and would benefit droplet generation, manipulation and design of microfluidic devices. PMID:26899018

48 CFR 15.406-1 - Prenegotiation objectives.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the results of the contracting officer's analysis of the offeror's proposal, taking into consideration all pertinent information including field pricing assistance, audit reports and technical analysis... and depth of the analysis supporting the objectives should be directly related to the dollar value...

48 CFR 15.406-1 - Prenegotiation objectives.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the results of the contracting officer's analysis of the offeror's proposal, taking into consideration all pertinent information including field pricing assistance, audit reports and technical analysis... and depth of the analysis supporting the objectives should be directly related to the dollar value...

Design, Development, and Preliminary Validation for a BioContainment System for MSR

NASA Astrophysics Data System (ADS)

Fumagalli, A.; Spagnoli, B.; Terribile, A.; Indrigo, D.; Romstedt, J.; Vjendran, S.; Kminek, G.

2018-04-01

A bio-containment system was conceived, designed, and tested by Leonardo S.p.A. and partners under ESA development contract. Results achieved so far are presented, including reports of the several tests performed on development hardware.

41 CFR 101-26.509-1 - Requisitioning tabulating machine cards available from Federal Supply Schedule contracts.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Requisitioning tabulating... Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT... electrical and mechanical contact tabulating machines, including aperture cards and copy cards. Federal...

41 CFR 101-26.509-1 - Requisitioning tabulating machine cards available from Federal Supply Schedule contracts.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Requisitioning tabulating... Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT... electrical and mechanical contact tabulating machines, including aperture cards and copy cards. Federal...

48 CFR 2015.209-70 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 2052.215-71, Project Officer Authority in applicable solicitations and contracts for cost-reimbursement, cost-plus-fixed-fee, cost-plus-award-fee, cost sharing, labor-hour or time-and-materials, including... for cost type contracts; (2) Section 2052.215-75 Alternate 1 may be used for all solicitations for...

48 CFR 619.811-1 - Sole source.

Code of Federal Regulations, 2011 CFR

2011-10-01

... contracting activity shall include SBA's requirement number on the award document. (4) A single award document... sign the contract as a third party. The 8(a) contractor's signature shall be placed on the award... and open competition. (2) The contracting officer shall insert FAR 52.219-14, Limitations on...

48 CFR 619.811-1 - Sole source.

Code of Federal Regulations, 2010 CFR

2010-10-01

... contracting activity shall include SBA's requirement number on the award document. (4) A single award document... sign the contract as a third party. The 8(a) contractor's signature shall be placed on the award... and open competition. (2) The contracting officer shall insert FAR 52.219-14, Limitations on...

Some Contracting Controls at Mission and Installation Contracting Command, Fort Polk, Louisiana, Need Improvement

DTIC Science & Technology

2015-02-12

erosion control. Work that did not meet PWS requirements included laying pavement stones for a monument walkway and installing a glossy marble -like... property structures, roads, training areas, training facilities, and utility infrastructure. The contract period of performance consisted of a base year

36 CFR Appendix A to Part 1210 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-07-01

... EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 1210, App. A Appendix A to Part 1210—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

24 CFR Appendix A to Part 84 - Contract Provisions

Code of Federal Regulations, 2010 CFR

2010-04-01

... EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 84, App. A Appendix A to Part 84—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following... which are unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of...

41 CFR Appendix A to Part 105 - 72-Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-01-01

..., HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 105-72, App. A Appendix A to Part 105-72—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

7 CFR Appendix A to Part 3019 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-01-01

... HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 3019, App. A Appendix A to Part 3019—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

15 CFR Appendix A to Part 14 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-01-01

... COMMERCIAL ORGANIZATIONS Pt. 14, App. A Appendix A to Part 14—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following provisions as applicable: 1. Equal... dangerous. These requirements do not apply to the purchases of supplies or materials or articles ordinarily...

24 CFR Appendix A to Part 84 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-04-01

... EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 84, App. A Appendix A to Part 84—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following... which are unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of...

34 CFR Appendix A to Part 74 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-07-01

... INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Pt. 74, App. A Appendix A to Part 74—Contract Provisions All contracts, awarded by a recipient including small purchases, shall... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

22 CFR Appendix A to Part 226 - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-04-01

...-GOVERNMENTAL ORGANIZATIONS Pt. 226, App. A Appendix A to Part 226—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the following provisions as applicable: 1... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

17 CFR 1.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... a transaction in the spot market for the commodity. (e) Commodity. This term means and includes... the Act. (h) Contract market; designated contract market. These terms mean a board of trade designated by the Commission as a contract market under the Act and in accordance with the provisions of part 38...

24 CFR 964.7 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Contributions Contract (ACC). A contract (in the form prescribed by HUD) under which HUD agrees to provide... activities for which the HA is responsible to HUD under the ACC, within the definition of “operation” under the Act and the ACC, including the development of resident programs and services. Management contract...

26 CFR 1.460-5 - Cost allocation rules.

Code of Federal Regulations, 2010 CFR

2010-04-01

... must be allocated to a long-term contract when dedicated to the contract under principles similar to... component is dedicated, under principles similar to those in § 1.263A-11(b)(2). A taxpayer maintaining... exempt construction contract reported using the CCM— (A) Marketing and selling expenses, including...

31 CFR 537.410 - Contracts and subcontracts regarding economic development of resources in Burma.

Code of Federal Regulations, 2011 CFR

2011-07-01

... economic development of resources in Burma. 537.410 Section 537.410 Money and Finance: Treasury Regulations... BURMESE SANCTIONS REGULATIONS Interpretations § 537.410 Contracts and subcontracts regarding economic... supervision and guarantee of another person's performance of a contract that includes the economic development...

48 CFR 19.502-2 - Total small business set-asides.

Code of Federal Regulations, 2010 CFR

2010-10-01

... purchases on an unrestricted basis, the contracting officer shall include in the contract file the reason for this unrestricted purchase. If the contracting officer receives only one acceptable offer from a... important, it is not the only factor to be considered in determining whether a reasonable expectation exists...

Contract Management Mentality--Are You Ready for the Spotlight?

ERIC Educational Resources Information Center

Whiddon, Philip

1994-01-01

Contract management of school maintenance and operations is a growing trend. In-house departments need to be prepared to justify their positions. Describes a Texas school district's request for proposal for contract management and includes the specifications for bidding with comments about the wording of the document. (MLF)

Preparing Contracts and Negotiating with Library Automation Vendors.

ERIC Educational Resources Information Center

Walton, Robert A.

This continuing education curriculum and related materials are designed to provide library professionals with a general orientation to the issues and process of negotiating and successfully securing an automation contract. The course syllabus includes the following topics: (1) definition and objectives of a contract; (2) why vendors typically have…

48 CFR 16.102 - Policies.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Policies. 16.102 Section 16.102 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Selecting Contract Types 16.102 Policies. (a) Contracts resulting from...

Performance of new alternative providers of primary care services in England: an observational study

PubMed Central

Greaves, Felix; Laverty, Anthony A; Pape, Utz; Ratneswaren, Anenta; Majeed, Azeem

2015-01-01

Summary Objectives Health system reforms in England are opening broad areas of clinical practice to new providers of care. As part of these reforms, new entrants – including private companies – have been allowed into the primary care market under ‘alternative provider of medical services’ contracting mechanisms since 2004. The characteristics and performance of general practices working under new alternative provider contracts are not well described. We sought to compare the quality of care provided by new entrant providers to that provided by the traditional model of general practice. Design Open cohort study of English general practices. We used linear regression in cross-sectional and time series analyses, adjusting for practice and population characteristics, to compare quality in practices using alternative provider contracts to traditional practices. We created regression models using practice fixed effects to estimate the impact of practices changing to the new contract type. Setting The English National Health Service. Participants All general practices open from 2008/2009 to 2012/2013. Main outcome measures Seventeen established quality indicators – covering clinical effectiveness, efficiency, access and patient experience. Results In total, 4.1% (347 of 8300) of general practices in England were run by alternative contract providers. These practices tended to be smaller, and serve younger, more diverse and more deprived populations than traditional providers. Practices run by alternative providers performed worse than traditional providers on 15 of 17 indicators after adjusting for practice and population characteristics (p < 0.01 for all). Switching to a new alternative provider contract did not result in improved performance. Conclusions The introduction of new alternative providers to deliver primary care services in England has not led to improvements in quality and may have resulted in worse care. Regulators should ensure that new entrants to clinical provider markets are performing to adequate standards and at least as well as traditional providers. PMID:25908312

DCAA Audits: Widespread Problems with Audit Quality Require Significant Reform

DTIC Science & Technology

2009-09-01

is included in appendix III. DOD contract management continues to be a high- risk area for the government.17 With hundreds of billions of taxpayer...Defense Contract Management : DOD’s Lack of Adherence to Key Contracting Principles on Iraq Oil Contract Put Government Interests at Risk , GAO-07-839...in the Federal Government68 require federal agency managers to identify and assess relevant risks the agency faces from external and internal

Department of Defense’s Waiver of Competitive Prototyping Requirement for Enhanced Polar System Program

DTIC Science & Technology

2012-08-23

objectives. Finally, the CAPS acquisition strategy anticipates the use of a cost- reimbursement contract for designing and building the system...The CAPS acquisition strategy anticipates the use of a cost- reimbursement contract for designing and building the system; however, it may be... reimbursement contract was chosen for the basic CAPS contract because of the nature of the design work, which includes software design and development

Contract Terminations for Default and Convenience.

DTIC Science & Technology

1981-06-01

principal rights acquired by the Government under the default clause, according to Govern- ment Contract Law (M8157), is the right to repurchase the 2 item...with the conver- sion of terminations from default to convenience in any detail (21:539). Government Contract Law presented an ex- cellent summary of...factors leading to the conversion were analyzed on the basis of the DAR, principles of contract law , and studies included in the literature review

Adenosine A1 receptors link to smooth muscle contraction via CYP4a, PKC-α, and ERK1/2

PubMed Central

Kunduri, SS; Mustafa, SJ; Ponnoth, DS; Dick, GM; Nayeem, MA

2013-01-01

Adenosine A1 receptor (A1AR) activation contracts smooth muscle, although signaling mechanisms aren’t thoroughly understood. Activation of A1AR leads to metabolism of arachidonic acid, including the production of 20-hydroxyeicosatetraenoic acid (20-HETE) by cytochrome P4504a (CYP4a). 20-HETE can activate protein kinase C-α (PKC-α) which crosstalks with extracellular signal-regulated kinase (ERK1/2) pathway. Both these pathways can regulate smooth muscle contraction, we tested the hypothesis that A1AR contracts smooth muscle through a pathway involving CYP4a, PKC-α, and ERK1/2. Experiments included isometric tension recordings of aortic contraction and Western blots of signaling molecules in wild type (WT) and A1AR knockout (A1KO) mice. Contraction to the A1-selective agonist CCPA was absent in A1KO mice aortae, indicating the contractile role of A1AR. Inhibition of CYP4a (HET0016) abolished CCPA-induced contraction in WT aortae, indicating a critical role for 20-HETE. Both WT and A1KO mice aortae contracted in response to exogenous 20-HETE. Inhibition of PKC-α (Gö6976) or ERK1/2 (PD98059) attenuated 20-HETE-induced contraction equally, suggesting that ERK1/2 is downstream of PKC-α. Contractions to exogenous 20-HETE were significantly less in A1KO mice; reduced protein levels of PKC-α, p-ERK1/2, and total ERK1/2 supported this observation. Our data indicate that A1AR mediates smooth muscle contraction via CYP4a and a PKC-α-ERK1/2 pathway. PMID:23519140

Adenosine A1 receptors link to smooth muscle contraction via CYP4a, protein kinase C-α, and ERK1/2.

PubMed

Kunduri, Swati S; Mustafa, S Jamal; Ponnoth, Dovenia S; Dick, Gregory M; Nayeem, Mohammed A

2013-07-01

Adenosine A1 receptor (A1AR) activation contracts smooth muscle, although signaling mechanisms are not thoroughly understood. Activation of A1AR leads to metabolism of arachidonic acid, including the production of 20-hydroxyeicosatetraenoic acid (20-HETE) by cytochrome P4504a (CYP4a). The 20-HETE can activate protein kinase C-α (PKC-α), which crosstalks with extracellular signal-regulated kinase (ERK1/2) pathway. Both these pathways can regulate smooth muscle contraction, we tested the hypothesis that A1AR contracts smooth muscle through a pathway involving CYP4a, PKC-α, and ERK1/2. Experiments included isometric tension recordings of aortic contraction and Western blots of signaling molecules in wild type (WT) and A1AR knockout (A1KO) mice. Contraction to the A1-selective agonist 2-chloro-N cyclopentyladenosine (CCPA) was absent in A1KO mice aortae, indicating the contractile role of A1AR. Inhibition of CYP4a (HET0016) abolished 2-chloro-N cyclopentyladenosine-induced contraction in WT aortae, indicating a critical role for 20-HETE. Both WT and A1KO mice aortae contracted in response to exogenous 20-HETE. Inhibition of PKC-α (Gö6976) or ERK1/2 (PD98059) attenuated 20-HETE-induced contraction equally, suggesting that ERK1/2 is downstream of PKC-α. Contractions to exogenous 20-HETE were significantly less in A1KO mice; reduced protein levels of PKC-α, p-ERK1/2, and total ERK1/2 supported this observation. Our data indicate that A1AR mediates smooth muscle contraction via CYP4a and a PKC-α-ERK1/2 pathway.

Challenges With Research Contract Negotiations in Community-Based Cancer Research.

PubMed

Thompson, Michael A; Hurley, Patricia A; Faller, Bryan; Longinette, Jean; Richter, Katie; Stewart, Teresa L; Robert, Nicholas

2016-06-01

Community-based research programs face many barriers to participation in clinical trials. Although the majority of people with cancer are diagnosed and treated in the community setting, only roughly 3% are enrolled onto clinical trials. Research contract and budget negotiations have been consistently identified as time consuming and a barrier to participation in clinical trials. ASCO's Community Research Forum conducted a survey about specific challenges of research contract and budget negotiation processes in community-based research settings. The goal was to ultimately identify potential solutions to these barriers. A survey was distributed to 780 community-based physician investigators and research staff. The survey included questions to provide insight into contract and budget negotiation processes and perceptions about related barriers. A total of 77% of the 150 respondents acknowledged barriers in the process. Respondents most frequently identified budget-related issues (n = 133), inefficiencies in the process (n = 80), or legal review and negotiation issues (n = 70). Of the respondents, 44.1% indicated that contract research organizations made the contract negotiations process harder for their research program, and only 5% believed contract research organizations made the process easier. The contract negotiations process is perceived to be impeded by sponsors through underestimation of costs, lack of flexibility with the contract language, and excessive delays. Improving clinical trial activation processes and reducing inefficiencies would be beneficial to all interested stakeholders, including patients who may ultimately stand to benefit from participation in clinical trials. The following key recommendations were made: standardization of contracts and negotiation processes to promulgate transparency and efficiencies, improve sponsor processes to minimize burden on sites, create and promote use of contract templates and best practices, and provide education and consultation. Copyright © 2016 by American Society of Clinical Oncology.

Computational Modeling of Morphogenesis Regulated by Mechanical Feedback

PubMed Central

Ramasubramanian, Ashok; Taber, Larry A.

2008-01-01

Mechanical forces cause changes in form during embryogenesis and likely play a role in regulating these changes. This paper explores the idea that changes in homeostatic tissue stress (target stress), possibly modulated by genes, drive some morphogenetic processes. Computational models are presented to illustrate how regional variations in target stress can cause a range of complex behaviors involving the bending of epithelia. These models include growth and cytoskeletal contraction regulated by stress-based mechanical feedback. All simulations were carried out using the commercial finite element code ABAQUS, with growth and contraction included by modifying the zero-stress state in the material constitutive relations. Results presented for bending of bilayered beams and invagination of cylindrical and spherical shells provide insight into some of the mechanical aspects that must be considered in studying morphogenetic mechanisms. PMID:17318485

48 CFR 1816.405-274 - Award fee evaluation factors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... factor, if used, must include consideration of risk management (including mission success, safety... above the contracting officer, with the concurrence of the project manager. The rationale for any waiver shall be documented in the contract file. When safety, export control, or security are considered under...

48 CFR 225.7017-1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... photovoltaic device, foreign photovoltaic device, Free Trade Agreement country photovoltaic device...— Covered contract means an energy savings performance contract, a utility service contract, or a private housing contract awarded by DoD, if such contract results in DoD ownership of photovoltaic devices, by...

48 CFR 225.7017-1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... photovoltaic device, foreign photovoltaic device, Free Trade Agreement country photovoltaic device...— Covered contract means an energy savings performance contract, a utility service contract, or a private housing contract awarded by DoD, if such contract results in DoD ownership of photovoltaic devices, by...

48 CFR 225.7017-1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... photovoltaic device, foreign photovoltaic device, Free Trade Agreement country photovoltaic device...— Covered contract means an energy savings performance contract, a utility service contract, or a private housing contract awarded by DoD, if such contract results in DoD ownership of photovoltaic devices, by...

Psychological contract breaches, organizational commitment, and innovation-related behaviors: a latent growth modeling approach.

PubMed

Ng, Thomas W H; Feldman, Daniel C; Lam, Simon S K

2010-07-01

This study examined the relationships among psychological contract breaches, organizational commitment, and innovation-related behaviors (generating, spreading, implementing innovative ideas at work) over a 6-month period. Results indicate that the effects of psychological contract breaches on employees are not static. Specifically, perceptions of psychological contract breaches strengthened over time and were associated with decreased levels of affective commitment over time. Further, increased perceptions of psychological contract breaches were associated with decreases in innovation-related behaviors. We also found evidence that organizational commitment mediates the relationship between psychological contract breaches and innovation-related behaviors. These results highlight the importance of examining the nomological network of psychological contract breaches from a change perspective.

41 CFR 102-80.105 - What information must be included in an equivalent level of safety analysis?

Code of Federal Regulations, 2011 CFR

2011-01-01

... of Safety Analysis § 102-80.105 What information must be included in an equivalent level of safety... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What information must be included in an equivalent level of safety analysis? 102-80.105 Section 102-80.105 Public Contracts and...

41 CFR 102-80.105 - What information must be included in an equivalent level of safety analysis?

Code of Federal Regulations, 2014 CFR

2014-01-01

... of Safety Analysis § 102-80.105 What information must be included in an equivalent level of safety... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What information must be included in an equivalent level of safety analysis? 102-80.105 Section 102-80.105 Public Contracts and...

41 CFR 102-80.105 - What information must be included in an equivalent level of safety analysis?

Code of Federal Regulations, 2013 CFR

2013-07-01

... of Safety Analysis § 102-80.105 What information must be included in an equivalent level of safety... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What information must be included in an equivalent level of safety analysis? 102-80.105 Section 102-80.105 Public Contracts and...

41 CFR 102-80.105 - What information must be included in an equivalent level of safety analysis?

Code of Federal Regulations, 2012 CFR

2012-01-01

... of Safety Analysis § 102-80.105 What information must be included in an equivalent level of safety... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What information must be included in an equivalent level of safety analysis? 102-80.105 Section 102-80.105 Public Contracts and...

Adolescent Sex Education: A Preventive Mental Health Measure.

ERIC Educational Resources Information Center

Obstfeld, Lisa S.; Meyers, Andrew W.

1984-01-01

This article addresses the issue of adolescent sex education as a means of preventing sexuality-related disorders, including: sexual dysfunction; sexual deviance; physical health problems often contracted from sexual activity; and various psychological and sociological ill effects resulting from unplanned pregnancies. (Author/CJB)

7 CFR 1466.20 - Application for contracts and selecting applications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... concerning soil, water and air quality; wildlife habitat; and ground and surface water conservation; (vi... include water conservation or irrigation efficiency practices, the State Conservationist will give... conservation practices; (ii) The magnitude of the expected environmental benefits resulting from the...

7 CFR 1466.20 - Application for contracts and selecting applications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... concerning soil, water and air quality; wildlife habitat; and ground and surface water conservation; (vi... include water conservation or irrigation efficiency practices, the State Conservationist will give... conservation practices; (ii) The magnitude of the expected environmental benefits resulting from the...

7 CFR 1466.20 - Application for contracts and selecting applications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... concerning soil, water and air quality; wildlife habitat; and ground and surface water conservation; (vi... include water conservation or irrigation efficiency practices, the State Conservationist will give... conservation practices; (ii) The magnitude of the expected environmental benefits resulting from the...

What happens to soil ecological properties when conservation reserve program land is disturbed

USDA-ARS?s Scientific Manuscript database

Each year, expiring Conservation Reserve Program (CRP) contracts results in the conversion of restored CRP land back to croplands, potentially reversing multiple ecological benefits including C sequestration potential and microbial biodiversity. We evaluated microbial community composition (fatty ac...

48 CFR 36.303-2 - Phase Two.

Code of Federal Regulations, 2010 CFR

2010-10-01

... potential phase-two technical evaluation factors include design concepts, management approach, key personnel... OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Two-Phase Design-Build Selection...

Evidence for P(2)-purinoceptors contribution in H(2)O(2)-induced contraction of rat aorta in the absence of endothelium.

PubMed

Shen, J Z; Zheng, X F; Kwan, C Y

2000-08-18

H(2)O(2) can contract many arteries, however the underlying mechanisms are not fully understood. This study aims to test whether H(2)O(2)-induced vasoconstriction could be functionally attributed to the activation of P(2)-purinoceptors in rat aorta and to explore its possible signaling mechanisms. Isometric tension recording of H(2)O(2) and ATP-induced contractions of rat aortic rings were compared in the absence or presence of various pharmacological tools to identify their possible common signaling pathways. Both H(2)O(2) and ATP induced transient phasic contractions in a concentration-dependent manner (1-1000 microM). Removal of endothelium potentiated the contractile responses to H(2)O(2) and to ATP. H(2)O(2) (30 microM)-induced phasic contraction could be abolished by catalase (800 U/ml), but not affected by SOD (150 U/ml), DMSO (5 mM) and apyrase (5 U/ml), suggesting no involvement of O(2)(-), hydroxyl free radicals and ATP release. Also, several receptor antagonists including phentolamine, atropine, methysergide and chlorpheniramine (each 3 microM) were without effect on H(2)O(2) (30 microM)-induced phasic contraction, suggesting no involvement of typical neurotransmitter release. However, both H(2)O(2) (30 microM) and ATP (1 mM)-induced phasic contractions not only presented homologous desensitization, but also showed heterogeneous desensitization. Furthermore, the phasic contractions in response to H(2)O(2) (30 microM) or ATP (100 microM) could be inhibited or abolished in a concentration dependent manner by RB-2 and suramin (10-100 microM), two widely used P(2)-purinoceptor antagonists, with only partial inhibition by Evans blue (300 microM), a moderately selective P(2x) receptor blocker, or by alpha-beta-methylene-ATP (100 microM), a selective P(2x) receptor desensitizer. On the other hand, both H(2)O(2) (30 microM) and ATP (100 microM)-induced phasic contractions were also attenuated, to different degree, by inhibitors of several enzymes including PLC, PKC, PLA(2) and cyclooxygenase. Lastly, removal of extracellular Ca(2+) or pretreatment with procaine (10 mM) and dantrolene (30 microM), two putative intracellular Ca(2+) release blockers, or with Ni(2+) (100 microM) and tetrandrine (5 microM), two Ca(2+) channel blockers, all significantly inhibited H(2)O(2) and ATP-induced contractions. However, nifedipine (1 microM), a voltage-dependent L-type Ca(2+) channel blocker, was without effect. Our results demonstrate that H(2)O(2)-induced phasic contraction of rat aorta involves, at least in part, the activation of P(2)-purinoceptors in the aortic smooth muscle cells

48 CFR 215.404-71-1 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... range provides values based on above normal or below normal conditions. In the price negotiation..., DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 215... contracting officer assigns values to each profit factor; the value multiplied by the base results in the...

48 CFR 337.103-70 - Solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 1994. (b) The Contracting Officer shall insert the clause in 352.237-71, Crime Control Act—Reporting of... specified in the Crime Control Act of 1990, including, but not limited to, physicians, nurses, dentists... drivers. (c) The Contracting Officer shall insert the clause in 352.237-72, Crime Control Act—Requirement...

42 CFR 421.200 - Carrier functions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Carrier functions. 421.200 Section 421.200 Public...) MEDICARE PROGRAM MEDICARE CONTRACTING Carriers § 421.200 Carrier functions. A contract between CMS and a carrier specifies the functions to be performed by the carrier. The contract may include any or all of the...

26 CFR 1.460-4 - Methods of accounting for long-term contracts.

Code of Federal Regulations, 2014 CFR

2014-04-01

... (CCM), which is one of the permissible methods of accounting for exempt construction contracts... computing taxable income. (3) Post-completion-year income. If a taxpayer has not included the total contract... completion year. For the treatment of post-completion-year costs, see paragraph (b)(5)(v) of this section...

26 CFR 1.460-4 - Methods of accounting for long-term contracts.

Code of Federal Regulations, 2011 CFR

2011-04-01

... (CCM), which is one of the permissible methods of accounting for exempt construction contracts... computing taxable income. (3) Post-completion-year income. If a taxpayer has not included the total contract... completion year. For the treatment of post-completion-year costs, see paragraph (b)(5)(v) of this section...

26 CFR 1.460-4 - Methods of accounting for long-term contracts.

Code of Federal Regulations, 2012 CFR

2012-04-01

... (CCM), which is one of the permissible methods of accounting for exempt construction contracts... computing taxable income. (3) Post-completion-year income. If a taxpayer has not included the total contract... completion year. For the treatment of post-completion-year costs, see paragraph (b)(5)(v) of this section...

26 CFR 1.460-4 - Methods of accounting for long-term contracts.

Code of Federal Regulations, 2010 CFR

2010-04-01

... (CCM), which is one of the permissible methods of accounting for exempt construction contracts... computing taxable income. (3) Post-completion-year income. If a taxpayer has not included the total contract... completion year. For the treatment of post-completion-year costs, see paragraph (b)(5)(v) of this section...

26 CFR 1.460-4 - Methods of accounting for long-term contracts.

Code of Federal Regulations, 2013 CFR

2013-04-01

... (CCM), which is one of the permissible methods of accounting for exempt construction contracts... computing taxable income. (3) Post-completion-year income. If a taxpayer has not included the total contract... completion year. For the treatment of post-completion-year costs, see paragraph (b)(5)(v) of this section...

48 CFR 15.407-1 - Defective certified cost or pricing data.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Defective certified cost or pricing data. (a) If, before agreement on price, the contracting officer learns... based on an agreement about the total cost of the contract and there was no agreement about the cost of..., based on prime contract progress billings or deliveries, which included payments for a completed and...

46 CFR 390.13 - Failure to fulfill a substantial obligation under the agreement.

Code of Federal Regulations, 2010 CFR

2010-10-01

.... Request to cure must include a proposal to cure the breach. If the Contracting Officer accepts the party's... whether there has been a failure to fulfill a substantial obligation under an agreement. (b) Contracting Officer's tentative conclusion—(1) Notice. If the Contracting Officer tentatively concludes that any...

7 CFR 1468.21 - Contract requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... provisions of § 1468.24 of this part; (iv) Agree to forego participation in CRP, EQIP, and the cost-share... those practices transferred from terminated CRP and EQIP contracts and WRP cost-share agreements. For persons wishing to transfer from CRP, EQIP, or WRP to CFO, practices included in CRP or EQIP contracts or...

48 CFR 728.313 - Contract clauses for insurance of transportation or transportation-related services.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses for insurance of transportation or transportation-related services. 728.313 Section 728.313 Federal Acquisition...) USAID is required by law to include language in all its direct contracts and subcontracts ensuring that...

48 CFR 52.222-4 - Contract Work Hours and Safety Standards Act-Overtime Compensation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... employing laborers or mechanics (see Federal Acquisition Regulation 22.300) shall require or permit them to... all laborers and mechanics working on the contract during the contract and shall make them available... mechanics and require subcontractors to include these provisions in any such lower tier subcontracts. The...

48 CFR 52.222-4 - Contract Work Hours and Safety Standards-Overtime Compensation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... laborers or mechanics (see Federal Acquisition Regulation 22.300) shall require or permit them to work over... basic payroll records for all laborers and mechanics working on the contract during the contract and... the employment of laborers and mechanics and require subcontractors to include these provisions in any...

48 CFR 52.222-4 - Contract Work Hours and Safety Standards Act-Overtime Compensation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... employing laborers or mechanics (see Federal Acquisition Regulation 22.300) shall require or permit them to... all laborers and mechanics working on the contract during the contract and shall make them available... mechanics and require subcontractors to include these provisions in any such lower tier subcontracts. The...

48 CFR 52.222-4 - Contract Work Hours and Safety Standards Act-Overtime Compensation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... employing laborers or mechanics (see Federal Acquisition Regulation 22.300) shall require or permit them to... all laborers and mechanics working on the contract during the contract and shall make them available... mechanics and require subcontractors to include these provisions in any such lower tier subcontracts. The...

10 CFR Appendix A to Subpart B of... - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-01-01

..., Hospitals, and Other Nonprofit Organizations Pt. 600, Subpt. B, App. A Appendix A to Subpart B of Part 600—Contract Provisions All contracts, awarded by a recipient including small purchases, shall contain the... not apply to the purchases of supplies or materials or articles ordinarily available on the open...

43 CFR Appendix A to Subpart F of... - Contract Provisions

Code of Federal Regulations, 2011 CFR

2011-10-01

... Organizations Pt. 12, Subpt. F, App. A Appendix A to Subpart F of Part 12—Contract Provisions All contracts awarded by a recipient, including small purchases, shall contain the following provisions as applicable: 1... which are unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of...

43 CFR Appendix A to Subpart F of... - Contract Provisions

Code of Federal Regulations, 2010 CFR

2010-10-01

... Organizations Pt. 12, Subpt. F, App. A Appendix A to Subpart F of Part 12—Contract Provisions All contracts awarded by a recipient, including small purchases, shall contain the following provisions as applicable: 1... which are unsanitary, hazardous or dangerous. These requirements do not apply to the purchases of...

13 CFR 126.607 - When must a contracting officer set aside a requirement for qualified HUBZone SBCs?

Code of Federal Regulations, 2012 CFR

2012-01-01

... fair market prices. This requirement does not preclude a contracting officer from setting aside a... will be made at fair market prices. However, after conducting market research, the contracting officer... to support the specific set-aside, including the type and extent of market research conducted. In...

77 FR 1723 - Proposed Concession Contract for Shenandoah National Park-Alternative Formula for Calculating...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-11

... we include in concession contracts a franchise fee payable to the Government that is based upon... establish the required minimum franchise fee for the new contract, that fee will reflect speculative... concessioner offers to meet or exceed the minimum franchise fee that we would establish under the standard LSI...

48 CFR 728.313 - Contract clauses for insurance of transportation or transportation-related services.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Contract clauses for insurance of transportation or transportation-related services. 728.313 Section 728.313 Federal Acquisition...) USAID is required by law to include language in all its direct contracts and subcontracts ensuring that...

48 CFR 728.313 - Contract clauses for insurance of transportation or transportation-related services.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Contract clauses for insurance of transportation or transportation-related services. 728.313 Section 728.313 Federal Acquisition...) USAID is required by law to include language in all its direct contracts and subcontracts ensuring that...

48 CFR 728.313 - Contract clauses for insurance of transportation or transportation-related services.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Contract clauses for insurance of transportation or transportation-related services. 728.313 Section 728.313 Federal Acquisition...) USAID is required by law to include language in all its direct contracts and subcontracts ensuring that...