Sample records for contributes significant amounts

  1. 40 CFR 51.121 - Findings and requirements for submission of State implementation plan revisions relating to...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... nitrogen oxides (“NOX”) in amounts that will contribute significantly to nonattainment in one or more other... provisions prohibiting sources and other activities from emitting NOX in amounts that will contribute... paragraph (c) of this section, the SIP revision required under paragraph (a) of this section will contain...

  2. 78 FR 57650 - Announcement of Funding Awards for the Self-Help Homeownership Opportunity Program (SHOP) for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ... significant amount of sweat equity towards the development of the SHOP units. Sweat equity involves... SHOP funds together with the homebuyer's sweat equity and volunteer labor contributions significantly... sweat equity contribution must not be mortgaged or otherwise restricted upon future sale of the SHOP...

  3. CONSTRUCTED WETLANDS VS. RETENTION POND BMPS: MESOCOSM STUDIES FOR IMPROVED POLLUTANT MANAGEMENT IN URBAN STORMWATER TREATMENT

    EPA Science Inventory

    Increased urbanization has increased the amount of directly connected impervious area that results in large quantities of stormwater runoff. This runoff can contribute significant amounts of debris and pollutants to receiving waters. Urban watershed managers often incorporate b...

  4. Potentially efficient forest and range applications of remote sensing using earth orbital space craft, circa 1980

    NASA Technical Reports Server (NTRS)

    Wilson, R. C.

    1970-01-01

    Sixteen remote sensing applications or groups of related applications judged to be most important of any in the forestry and range disciplines were evaluated. In one application, major land classification, large amounts of useful data are anticipated to be contributed by space sensors in 1980. In four applications moderate amounts are anticipated to be so contributed. These are timber inventory, range inventory, fire weather forecasting, and monitoring snowfields. In the following seven applications small but significant amounts of data are anticipated to be contributed by space sensors: (1) detailed land classification; (2) inventory of wildlife habitat; (3) recreation resource inventory; (4) detecting stresses on the vegetation (5) monitoring air pollution caused by wildfires and prescribed burning; (6) monitoring water cycle, (7) pollution and erosion; and (8) evaluating damage to forests and ranges.

  5. FACTORS CONTRIBUTING TO STUDENT ACHIEVEMENT.

    ERIC Educational Resources Information Center

    Ohio State Dept. of Education, Columbus. Trade and Industrial Education Service.

    FACTORS WHICH MIGHT CONTRIBUTE SIGNIFICANTLY TOWARD STUDENT ACHIEVEMENT IN SELECTED TRADE AND INDUSTRIAL EDUCATION AREAS WERE EXAMINED -- WHAT IS THE BACKGROUND AND PREPARATION OF OHIO'S TEACHER IN TRADE AND INDUSTRIAL EDUCATION, IS THERE ANY RELATIONSHIP BETWEEN THE AMOUNT OF MONEY SPENT PER STUDENT AND QUALITY PROGRAMS, DO LOCAL SUPERVISORS'…

  6. The pleasurable recreational activities among community-dwelling older adults.

    PubMed

    Onishi, Joji; Masuda, Yuichiro; Suzuki, Yusuke; Gotoh, Tadao; Kawamura, Takashi; Iguchi, Akihisa

    2006-01-01

    This study aimed to clarify what pleasurable recreational activities older adults like to participate in, and to investigate the relationship between those activities and quality of life (QOL). Questionnaires were delivered to older residents (65 years and above) in a Japanese rural area. The residents' background information, the amount of pleasure for various activities, and the QOL were surveyed. The QOL was evaluated by the revised Philadelphia Geriatric Center (PGC) morale scale. The amount of pleasure taken in a majority of the activities, such as conversation with family or neighbors showed a significant association with the happiness score, but only a few activities showed significant association between the revised PGC morale scale and the amount of pleasure. The multiple regression analyses indicated that the amount of pleasure in exercise, the difficulty in managing finances, and amount of pleasure taken in watching TV were significant variables for predicting the happiness score. The results indicated that the amount of pleasure older adults experienced when engaging in activities such as conversation with family or neighbors showed significant association with the older adults' happiness. These results may be helpful in understanding contributions of various activities to the perception of pleasure in older adults.

  7. Quality over Quantity: Contribution of Urban Green Space to Neighborhood Satisfaction

    PubMed Central

    Zhang, Yang; Van den Berg, Agnes E.; Van Dijk, Terry; Weitkamp, Gerd

    2017-01-01

    There is increasing evidence that the quality of green space significantly contributes to neighborhood satisfaction and well-being, independent of the mere amount of green space. In this paper, we examined residents’ perceptions of the quality and beneficial affordances of green space in relation to objectively assessed accessibility and usability. We used data from a survey in two neighborhoods (N = 223) of a medium-sized city in the Netherlands, which were similar in the amount of green space and other physical and socio-demographic characteristics, but differed in the availability of accessible and usable green spaces. Results show that residents of the neighborhood with a higher availability of accessible and usable green spaces were more satisfied with their neighborhood. This difference was statistically mediated by the higher level of perceived green space quality. Neighborhood satisfaction was significantly positively related to well-being. However, residents of the two neighborhoods did not differ in self-reported well-being and beneficial affordances of green space. These analyses contribute to a further understanding of how the accessibility and usability of green spaces may increase people’s neighborhood satisfaction. It highlights the importance of perceived quality in addition to the amount of green space when examining the beneficial effects of green space. PMID:28509879

  8. Quality over Quantity: Contribution of Urban Green Space to Neighborhood Satisfaction.

    PubMed

    Zhang, Yang; Van den Berg, Agnes E; Van Dijk, Terry; Weitkamp, Gerd

    2017-05-16

    There is increasing evidence that the quality of green space significantly contributes to neighborhood satisfaction and well-being, independent of the mere amount of green space. In this paper, we examined residents' perceptions of the quality and beneficial affordances of green space in relation to objectively assessed accessibility and usability. We used data from a survey in two neighborhoods ( N = 223) of a medium-sized city in the Netherlands, which were similar in the amount of green space and other physical and socio-demographic characteristics, but differed in the availability of accessible and usable green spaces. Results show that residents of the neighborhood with a higher availability of accessible and usable green spaces were more satisfied with their neighborhood. This difference was statistically mediated by the higher level of perceived green space quality. Neighborhood satisfaction was significantly positively related to well-being. However, residents of the two neighborhoods did not differ in self-reported well-being and beneficial affordances of green space. These analyses contribute to a further understanding of how the accessibility and usability of green spaces may increase people's neighborhood satisfaction. It highlights the importance of perceived quality in addition to the amount of green space when examining the beneficial effects of green space.

  9. How insurance affects altruistic provision in threshold public goods games.

    PubMed

    Zhang, Jianlei; Zhang, Chunyan; Cao, Ming

    2015-03-13

    The occurrence and maintenance of cooperative behaviors in public goods systems have attracted great research attention across multiple disciplines. A threshold public goods game requires a minimum amount of contributions to be collected from a group of individuals for provision to occur. Here we extend the common binary-strategy combination of cooperation and defection by adding a third strategy, called insured cooperation, which corresponds to buying an insurance covering the potential loss resulted from the unsuccessful public goods game. Particularly, only the contributing agents can opt to be insured, which is an effort decreasing the amount of the potential loss occurring. Theoretical computations suggest that when agents face the potential aggregate risk in threshold public goods games, more contributions occur with increasing compensation from insurance. Moreover, permitting the adoption of insurance significantly enhances individual contributions and facilitates provision, especially when the required threshold is high. This work also relates the strategy competition outcomes to different allocation rules once the resulted contributions exceed the threshold point in populations nested within a dilemma.

  10. Contribution of Soil Moisture Information to Streamflow Prediction in the Snowmelt Season: A Continental-Scale Analysis

    NASA Technical Reports Server (NTRS)

    Reichle, Rolf; Mahanama, Sarith; Koster, Randal; Lettenmaier, Dennis

    2009-01-01

    In areas dominated by winter snowcover, the prediction of streamflow during the snowmelt season may benefit from three pieces of information: (i) the accurate prediction of weather variability (precipitation, etc.) leading up to and during the snowmelt season, (ii) estimates of the amount of snow present during the winter season, and (iii) estimates of the amount of soil moisture underlying the snowpack during the winter season. The importance of accurate meteorological predictions and wintertime snow estimates is obvious. The contribution of soil moisture to streamflow prediction is more subtle yet potentially very important. If the soil is dry below the snowpack, a significant fraction of the snowmelt may be lost to streamflow and potential reservoir storage, since it may infiltrate the soil instead for later evaporation. Such evaporative losses are presumably smaller if the soil below the snowpack is wet. In this paper, we use a state-of-the-art land surface model to quantify the contribution of wintertime snow and soil moisture information -- both together and separately -- to skill in forecasting springtime streamflow. We find that soil moisture information indeed contributes significantly to streamflow prediction skill.

  11. BMP UNIT PROCESS DESIGN, MONITORING, AND PERFORMANCE

    EPA Science Inventory

    Urbanization results in more impervious areas that cause larger quantities of stormwater runoff. This runoff can contribute significant amounts of pollutants (e.g., litter, oils, microorganisms, sediments, nutrients, organic matter, and heavy metals) to receiving waters. To impro...

  12. IMPROVED POLLUTANT MANAGEMENT IN URBAN STORMWATER BMPS

    EPA Science Inventory

    Increased urbanization has resulted in a larger percentage of impervious areas that produce large quantities of stormwater runoff and contribute significant amounts of debris and pollutants (e.g., litter, oils, heavy metals, sediments, nutrients, organic matter, and microorganism...

  13. 7 CFR 1486.210 - Are there any limits on the funding of proposals?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... appropriate assistance to projects which also have a significant amount of financial contributions from other... is generally limited to 3 years. After that time, the project is assumed to have proven its viability...

  14. Lean beef contributes significant amounts of key nutrients to the diets of US adults: National Health and Nutrition Examination Survey 1999-2004

    USDA-ARS?s Scientific Manuscript database

    Consumption of lean meat is a valuable addition to a healthy diet because it provides complete protein and is a rich source of vitamin B12, iron, and zinc. The objective of this study was to examine the nutritional contribution of total beef and lean beef (LB) to the American diet using the USDA def...

  15. USE OF NATURAL FILTER MEDIA FOR STORMWATER TREATMENT

    EPA Science Inventory

    The overall objective of this study ws to evaluate the feasibility of low-cost and readily available natural filter material for stormwater treatment. Previous research indicates that urban SW contributes a significant amount of contamination (including heavy metals and PAHs) to ...

  16. USING PROTEOMICS TO MONITOR PROTEIN EXPRESSION IN HUMAN CELLS EXPOSED TO CARCINOGENS

    EPA Science Inventory

    People are continuously exposed exogenously to varying amounts of chemicals that have been shown to have carcinogenic properties in experimental systems. It has been estimated that exposure to environmental chemical carcinogens in the environment may contribute significantly to t...

  17. ORGANOCHLORINE PESTICIDES IN THE AMBIENT AIR OF MEXICO

    EPA Science Inventory

    Recent and past use of organochlorine pesticides (OCPs) in Mexico has resulted in concentrations in ambient air that are 1-2 orders of magnitude above levels in the Great Lakes region. Atmospheric transport from Mexico and Central America may be contributing significant amounts ...

  18. Campaign contributions, lobbying and post-Katrina contracts.

    PubMed

    Hogan, Michael J; Long, Michael A; Stretesky, Paul B

    2010-07-01

    This research explores the relationship between political campaign contributions, lobbying and post-Hurricane Katrina cleanup and reconstruction contracts. Specifically, a case-control study design is used to determine whether campaign contributions to national candidates in the 2000-04 election cycles and/or the employment of lobbyists and lobbying firms increased a company's probability of receiving a post-hurricane contract. Results indicate that both a campaign contribution dichotomous variable and the dollar amount of contributions are significantly related to whether a company received a contract, but that lobbying activity was not. These findings are discussed in the context of previous research on the politics of natural disasters, government contracting and governmental and corporate deviance.

  19. Alcohol use by undergraduate students on their 21st birthday: predictors of actual consumption, anticipated consumption, and normative beliefs.

    PubMed

    Day-Cameron, Jennifer M; Muse, Lauren; Hauenstein, Jennifer; Simmons, Lisa; Correia, Christopher J

    2009-12-01

    Recent research has identified celebration of a 21st birthday as an environmental event during which many college students engage in risky levels of alcohol consumption. The current study examined the relationship between personality and different aspects of alcohol use during 21st birthday celebrations: actual amount consumed for those who had turned 21, anticipated amount consumed for those under the age of 21, and normative beliefs regarding the amount other students consume on their 21st birthdays. Sensation seeking and impulsivity both displayed significant bivariate relationships with all three aspects of 21st birthday drinking. Personality traits did not contribute unique variance to actual 21st birthday drinking after the effects of typical alcohol consumption were accounted for in the models. Impulsivity contributed unique variance to models accounting for anticipated drinking and normative beliefs. Additional research is necessary to better understand the role personality variables play on alcohol consumption during 21st birthday celebrations. Copyright 2009 APA

  20. Chemical and biological quality of streams at the Indiana Dunes National Lakeshore, Indiana, 1978-80

    USGS Publications Warehouse

    Hardy, M.A.

    1984-01-01

    Wetland drainage contributed significant amounts of organic materials to streams and at times increased concentrations of dissolved sulfate and iron. Dissolved-iron concentrations correlated with dissolved-organic-carbon concentrations in yellow-brown water of Kintzele and Derby ditches.

  1. Apical extrusion of debris during the preparation of oval root canals: a comparative study between a full-sequence SAF system and a rotary file system supplemented by XP-endo finisher file.

    PubMed

    Kfir, Anda; Moza-Levi, Rotem; Herteanu, Moran; Weissman, Amir; Wigler, Ronald

    2018-03-01

    The purpose of this study was to assess the amount of apically extruded debris during the preparation of oval canals with either a rotary file system supplemented by the XP-endo Finisher file or a full-sequence self-adjusting file (SAF) system. Sixty mandibular incisors were randomly assigned to two groups: group A: stage 1-glide path preparation with Pre-SAF instruments. Stage 2-cleaning and shaping with SAF. Group B: stage 1-glide path preparation with ProGlider file. Stage 2-cleaning and shaping with ProTaper Next system. Stage 3-Final cleaning with XP-endo Finisher file. The debris extruded during each of the stages was collected, and the debris weights were compared between the groups and between the stages within the groups using t tests with a significance level set at P < 0.05. The complete procedure for group B resulted in significantly more extruded debris compared to group A. There was no significant difference between the stages in group A, while there was a significant difference between stage 2 and stages 1 and 3 in group B, but no significant difference between stages 1 and 3. Both instrumentation protocols resulted in extruded debris. Rotary file followed by XP-endo Finisher file extruded significantly more debris than a full-sequence SAF system. Each stage, in either procedure, had its own contribution to the extrusion of debris. Final preparation with XP-endo Finisher file contributes to the total amount of extruded debris, but the clinical relevance of the relative difference in the amount of apically extruded debris remains unclear.

  2. Influence of climate on alpine stream chemistry and water sources

    USGS Publications Warehouse

    Foks, Sydney; Stets, Edward; Singha, Kamini; Clow, David W.

    2018-01-01

    The resilience of alpine/subalpine watersheds may be viewed as the resistance of streamflow or stream chemistry to change under varying climatic conditions, which is governed by the relative size (volume) and transit time of surface and subsurface water sources. Here, we use end‐member mixing analysis in Andrews Creek, an alpine stream in Rocky Mountain National Park, Colorado, from water year 1994 to 2015, to explore how the partitioning of water sources and associated hydrologic resilience change in response to climate. Our results indicate that four water sources are significant contributors to Andrews Creek, including snow, rain, soil water, and talus groundwater. Seasonal patterns in source‐water contributions reflected the seasonal hydrologic cycle, which is driven by the accumulation and melting of seasonal snowpack. Flushing of soil water had a large effect on stream chemistry during spring snowmelt, despite making only a small contribution to streamflow volume. Snow had a large influence on stream chemistry as well, contributing large amounts of water with low concentrations of weathering products. Interannual patterns in end‐member contributions reflected responses to drought and wet periods. Moderate and significant correlations exist between annual end‐member contributions and regional‐scale climate indices (the Palmer Drought Severity Index, the Palmer Hydrologic Drought Index, and the Modified Palmer Drought Severity Index). From water year 1994 to 2015, the percent contribution from the talus‐groundwater end member to Andrews Creek increased an average of 0.5% per year (p < 0.0001), whereas the percent contributions from snow plus rain decreased by a similar amount (p = 0.001). Our results show how water and solute sources in alpine environments shift in response to climate variability and highlight the role of talus groundwater and soil water in providing hydrologic resilience to the system.

  3. Impact of food choice on sodium intake patterns from multiple NHANES surveys.

    PubMed

    Dong, Zefeng; Gao, Zhifeng; McFadden, Brandon

    2017-02-01

    To examine how the food consumption from various food groups would impact American adults' sodium intake and whether this impact structurally changes over time, data were obtained from six-cycle National Health and Nutrition Examination Survey (NHANES) 1999-2010. Foods were categorized by the first two digits of the USDA food code. Regression models were employed to investigate the associations between the consumption of each food group and sodium intake, and whether there were changes in the associations in consecutive six cycles. Results show that the calorie consumption of oils, beverages and water, fruit juices, fruits, lamb, fruit products, and sugars and sweets had no significant impact on individuals' sodium intake, while calorie consumption of tomatoes, fish, dark-green vegetables, and crackers contributes the most to sodium intake. The contribution to sodium intake of most food groups does not change significantly over time, with the exception of salad dressing whose contribution to sodium intake increased in four consecutive years when compared to that of 1999-2000. The sodium amount contributed by one calorie consumption (sodium density) of most food was above the daily recommendation level, 1.2 mg per calorie per day. Lowering individuals' sodium intake involves either guiding individuals to consume more fruit related products or decreasing the amount of sodium in most food groups at the production or food preparation stages. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Analysis of change in gait in the ovine stifle: normal, injured, and anterior cruciate ligament reconstructed.

    PubMed

    Heard, B J; Beveridge, J E; Atarod, M; O'Brien, E J; Rolian, C; Frank, C B; Hart, D A; Shrive, N G

    2017-05-23

    Many patients who undergo anterior cruciate ligament (ACL) reconstructive surgery develop post-traumatic osteoarthritis (PTOA). ACL reconstructive surgery may not fully restore pre-injury joint biomechanics, thereby resulting in further joint damage and contributing to the development of PTOA. In an ovine model of idealized ACL reconstruction (ACL-R), it has been shown that signs of PTOA develop within surgical joints by 20 weeks post-surgery. The aim of the present study was to investigate whether altered kinematics contribute to early PTOA development within ACL-R joints of the ovine injury model by comparing the gait of these surgical animals to the gait of a stable normal control group, and an unstable injury group in which the ACL and medial collateral ligament (MCL) had been transected. Fifteen skeletally mature female sheep were allocated evenly into 3 treatment groups: normal control, ACL-R, and ACL/MCL Tx (each group n = 5). Each animal's gait was recorded at baseline, 4 weeks post injury, and 20 weeks post injury. Principal component analysis (PCA) was used to identify the kinematic patterns that may be discriminant between treatment groups. Results from previous studies were referenced to present the amount of gross PTOA-like changes that occurred in the joints. ACL-R and ACL/MCL transected (Tx) animals developed a similar amount of early PTOA-like changes within the surgical joints, but differed significantly in the amount of kinematic change present at 20 weeks post-surgery. We showed that the stifle joint kinematics of ACL/MCL Tx differed significantly from those of CTRL and the majority of ACL-R animals, while no significant differences in joint kinematic changes were found between ACL-R and CTRL animals. These results suggest that the early PTOA-like changes reported in the ACL-R model cannot be attributed exclusively to post-surgical kinematic changes, and therefore biologic components in the post-injury environment must be contributing significantly to PTOA development.

  5. Concentrations and sources of cadmium, copper, lead and zinc in house dust in Christchurch, New Zealand.

    PubMed

    Kim, N; Fergusson, J

    1993-09-30

    The amounts (microgram m-2) and concentrations (microgram g-1) of cadmium, copper, lead and zinc have been measured in house dust in Christchurch, New Zealand. For 120 houses surveyed the geometric mean concentrations of the four metals are 4.24 micrograms g-1, 165 micrograms g-1, 573 micrograms g-1 and 10,400 micrograms g-1, respectively. In addition eleven variables, such as house age, carpet wear and traffic density, were recorded for each property and the results analysed with respect to their effects on the amounts and concentrations of the four elements. The amounts of all the metals were highly correlated with the overall dustiness of the houses, which was found to be predominantly determined by the degree of carpet wear. No one dominant source of cadmium was identified, although several minor sources including carpet wear, galvanized iron roofs and red/orange/yellow coloured carpets were implicated. Petrol lead and lead-based paints were identified as significant sources of lead in house dust. Rubber carpet underlays or backings were identified as a significant source of zinc, with some contribution from galvanized iron roofs. Road traffic and probably the existence of a fire place appear to contribute to the copper levels.

  6. Chemical weathering on the North Island of New Zealand: CO2 consumption and fluxes of Sr and Os

    NASA Astrophysics Data System (ADS)

    Blazina, Tim; Sharma, Mukul

    2013-09-01

    We present Os and Sr isotope ratios and Os, Sr and major/trace element concentrations for river waters, spring waters and rains on the North Island of New Zealand. The Os and Sr data are used to examine whether the NINZ is a significant contributor of unradiogenic Os and Sr to the oceans. Major element chemistry is used to quantify weathering and CO2 consumption rates on the island to investigate relationships between these processes and Os and Sr behavior. Chemical erosion rates and CO2 consumption rates across the island range from 44 to 555 km-2 yr-1 and 95 to 1900 × 103 mol CO2 km-2 yr-1, respectively. Strontium flux for the island range from 177 to 16,100 mol km-2 yr-1 and the rivers have an average flux normalized 87Sr/86Sr ratio of 0.7075. In agreement with the previous studies these findings provide further evidence that weathering of arc terrains contributes a disproportionally large amount of Sr to the oceans and consumes very large amounts of CO2 annually compared to their areal extent. However, the 87Sr/86Sr from the NINZ is not particularly unradiogenic and it is likely not contributing significant amounts of unradiogenic Sr to the oceans. Repeated Os analyses and bottle leaching experiments revealed extensive and variable sample contamination by Os leaching from rigorously precleaned LDPE bottles. An upper bound on the flux of Os from NINZ can nevertheless be assessed and indicates that island arcs cannot provide significant amounts of unradiogenic Os to the oceans.

  7. Contribution of dietary oxalate to urinary oxalate excretion

    NASA Technical Reports Server (NTRS)

    Holmes, R. P.; Goodman, H. O.; Assimos, D. G.

    2001-01-01

    BACKGROUND: The amount of oxalate excreted in urine has a significant impact on calcium oxalate supersaturation and stone formation. Dietary oxalate is believed to make only a minor (10 to 20%) contribution to the amount of oxalate excreted in urine, but the validity of the experimental observations that support this conclusion can be questioned. An understanding of the actual contribution of dietary oxalate to urinary oxalate excretion is important, as it is potentially modifiable. METHODS: We varied the amount of dietary oxalate consumed by a group of adult individuals using formula diets and controlled, solid-food diets with a known oxalate content, determined by a recently developed analytical procedure. Controlled solid-food diets were consumed containing 10, 50, and 250 mg of oxalate/2500 kcal, as well as formula diets containing 0 and 180 mg oxalate/2500 kcal. Changes in the content of oxalate and other ions were assessed in 24-hour urine collections. RESULTS: Urinary oxalate excretion increased as dietary oxalate intake increased. With oxalate-containing diets, the mean contribution of dietary oxalate to urinary oxalate excretion ranged from 24.4 +/- 15.5% on the 10 mg/2500 kcal/day diet to 41.5 +/- 9.1% on the 250 mg/2500 kcal/day diet, much higher than previously estimated. When the calcium content of a diet containing 250 mg of oxalate was reduced from 1002 mg to 391 mg, urinary oxalate excretion increased by a mean of 28.2 +/- 4.8%, and the mean dietary contribution increased to 52.6 +/- 8.6%. CONCLUSIONS: These results suggest that dietary oxalate makes a much greater contribution to urinary oxalate excretion than previously recognized, that dietary calcium influences the bioavailability of ingested oxalate, and that the absorption of dietary oxalate may be an important factor in calcium oxalate stone formation.

  8. CONSTRUCTED WETLANDS VS. RETENTION PONDS BMPS: THE ROLE OF VEGETATION IN IMPROVED POLLUTANT MANAGEMENT FOR URBAN STORMWATER TREATMENT

    EPA Science Inventory

    Increased urbanization has resulted in a larger percentage of impervious areas that produce large quantities of stormwater runoff and contribute significant amounts of debris and pollutants (e.g., litter, oils, heavy metals, sediments, nutrients, organic matter, and microorganism...

  9. Corn yield and nutrient uptake response to subsurface-lateral bands application of poultry litter

    USDA-ARS?s Scientific Manuscript database

    Poultry litter is nutrient rich and traditionally land-applied by broadcast on the soil surface which can lead to potential environmental hazards. This application method leaves PL vulnerable to transport from the field to nearby water bodies and contributes significant amounts of greenhouse gases (...

  10. Learning Vocabulary via Computer-Assisted Scaffolding for Text Processing

    ERIC Educational Resources Information Center

    Li, Jia

    2010-01-01

    A substantial amount of literature regarding first language (L1) acquisition has shown that reading for meaning significantly contributes to vocabulary expansion and strongly relates to overall academic success. Research in the English as a Second Language (ESL) context, however, has presented mixed results, in particular for recent immigrant…

  11. Amount and type of everyday technology use over time in older adults with cognitive impairment.

    PubMed

    Hedman, Annicka; Nygård, Louise; Almkvist, Ove; Kottorp, Anders

    2015-05-01

    This two-year study examined everyday technology (ET) use in older adults with mild cognitive impairment (MCI) testing five predefined theoretical assumptions regarding factors potentially influencing the amount of ET used in everyday life. Data from 37 participants with MCI were collected at inclusion, six, 12, and 24 months, on the type and amount of ET used and how difficult this was, activity involvement, and cognitive and diagnostic status. These variables were, together with age group (55-64, 65-74, or 75-84 years) and educational level, analysed in a mixed-linear-effect model. A significant decrease in the overall amount of ET used was found over time, but the number of users of specific ETs both decreased and increased. Increasing perceived difficulty in ET use, less activity involvement, decreasing cognitive status, and belonging to the oldest age group significantly decreased ET use. Two years after inclusion 42% of the participants had converted to dementia, but neither change in diagnostic status nor length of education contributed significantly to the predictive model. Over time, a decreasing use of ET was shown in this sample with MCI. This process was influenced by several aspects important to consider in occupational therapy intervention planning.

  12. 26 CFR 31.3302(e)-1 - Successor employer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... predecessor pays remuneration, subject to contributions under the unemployment compensation law of a State, to... is the total amount of remuneration, subject to such contributions, paid by the predecessor during... fraction is the total amount of remuneration, subject to such contributions, paid by the predecessor during...

  13. Disentangling the contribution of the paretic and non-paretic ankle to balance control in stroke patients.

    PubMed

    van Asseldonk, Edwin H F; Buurke, Jaap H; Bloem, Bastiaan R; Renzenbrink, Gerbert J; Nene, Anand V; van der Helm, Frans C T; van der Kooij, Herman

    2006-10-01

    During stroke recovery, restoration of the paretic ankle and compensation in the non-paretic ankle may contribute to improved balance maintenance. We examine a new approach to disentangle these recovery mechanisms by objectively quantifying the contribution of each ankle to balance maintenance. Eight chronic hemiparetic patients were included. Balance responses were elicited by continuous random platform movements. We measured body sway and ground reaction forces below each foot to calculate corrective ankle torques in each leg. These measurements yielded the Frequency Response Function (FRF) of the stabilizing mechanisms, which expresses the amount and timing of the generated corrective torque in response to sway at the specified frequencies. The FRFs were used to calculate the relative contribution of the paretic and non-paretic ankle to the total amount of generated corrective torque to correct sway. All patients showed a clear asymmetry in the balance contribution in favor of the non-paretic ankle. Paretic balance contribution was significantly smaller than the contribution of the paretic leg to weight bearing, and did not show a clear relation with the contribution to weight bearing. In contrast, a group of healthy subjects instructed to distribute their weight asymmetrically showed a one-on-one relation between the contribution to weight bearing and to balance. We conclude that the presented approach objectively quantifies the contribution of each ankle to balance maintenance. Application of this method in longitudinal surveys of balance rehabilitation makes it possible to disentangle the different recovery mechanisms. Such insights will be critical for the development and evaluation of rehabilitation strategies.

  14. Low Data Drug Discovery with One-Shot Learning.

    PubMed

    Altae-Tran, Han; Ramsundar, Bharath; Pappu, Aneesh S; Pande, Vijay

    2017-04-26

    Recent advances in machine learning have made significant contributions to drug discovery. Deep neural networks in particular have been demonstrated to provide significant boosts in predictive power when inferring the properties and activities of small-molecule compounds (Ma, J. et al. J. Chem. Inf. 2015, 55, 263-274). However, the applicability of these techniques has been limited by the requirement for large amounts of training data. In this work, we demonstrate how one-shot learning can be used to significantly lower the amounts of data required to make meaningful predictions in drug discovery applications. We introduce a new architecture, the iterative refinement long short-term memory, that, when combined with graph convolutional neural networks, significantly improves learning of meaningful distance metrics over small-molecules. We open source all models introduced in this work as part of DeepChem, an open-source framework for deep-learning in drug discovery (Ramsundar, B. deepchem.io. https://github.com/deepchem/deepchem, 2016).

  15. 5 CFR 870.401 - Withholdings and contributions for Basic insurance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... employing agency must contribute an amount equal to one-half the amount withheld from the employee's pay... individual's pay, annuity, or compensation, the agency must submit an amount equal to the sum of the... between the insured individual and the Government. The employee pays two-thirds of the cost, and the...

  16. The first nitrogen index app for mobile devices: using portable technology for smart agricultural management

    USDA-ARS?s Scientific Manuscript database

    Nitrogen fertilizer from organic and inorganic sources is used across the world’s agroecosystems. It contributes to higher yields and higher economic returns to farmers, and is essential for food security. However, when more is applied than necessary, significant amounts of nitrogen can exit the sy...

  17. A Social Epistemology for Educational Administration and Leadership

    ERIC Educational Resources Information Center

    Eacott, Scott

    2017-01-01

    As a field of knowledge production, educational administration and leadership scholars do a substantial amount of talking past one another. These parallel monologues are a major issue for the advancement of knowledge. Original contributions can only be made in relation to others. That is, the innovation or significance of scholarship is an act of…

  18. Public Internet Access Points (PIAPs) and Their Social Impact: A Case Study from Turkey

    ERIC Educational Resources Information Center

    Afacan, Gulgun; Er, Erkan; Arifoglu, Ali

    2013-01-01

    Building public Internet access points (PIAPs) is a significant contribution of governments towards achieving an information society. While many developing countries are investing great amounts to establish PIAPs today, people may not use PIAPs effectively. Yet, the successful implementation of PIAPs is the result of citizens' acceptance to use…

  19. Chocolate: A Heart-healthy Food? Show Me the Science!

    PubMed

    Hannum, Sandra M.; Schmitz, Harold H.; Keen, Carl L.

    2002-01-01

    Cocoa and chocolate foods produced by appropriate methods can contribute significant amounts of heart-healthy flavanols to the diet. These flavanols may enhance cardiovascular health by delaying blood clotting, improving vascular endothelial function, and helping to moderate inflammation. The benefits of chocolate can be enjoyed without guilt as part of a healthful balanced diet.

  20. Smoker Reactivity to Cues: Effects on Craving and on Smoking behavior

    PubMed Central

    Shiffman, Saul; Dunbar, Michael; Kirchner, Thomas; Li, Xiaoxue; Tindle, Hilary; Anderson, Stewart; Scholl, Sarah

    2013-01-01

    We assessed craving and smoking in response to smoking-relevant cues. 207 daily smokers viewed images related to one of six cue sets (cigarettes, positive and negative affect, alcohol, smoking prohibitions, and neutral cues) in separate sessions. Compared to neutral cues, cigarette cues significantly increased craving, and positive affect cues significantly decreased craving. When subjects were then allowed to smoke during continuing cue exposure, cues did not affect the likelihood of smoking or the amount smoked (number of cigarettes, number of puffs, puff time, or increased carbon monoxide). However, craving intensity predicted likelihood of smoking, latency to smoke, and amount smoked, with craving increases after cue exposure making significant independent contributions. Some craving effects were curvilinear, suggesting that they are subject to thresholds and might not be observed under some circumstances. PMID:22708884

  1. Transfer of blood urea nitrogen to cecal microbial nitrogen is increased by fructo-oligosaccharide feeding in guinea pigs.

    PubMed

    Kawasaki, Kiyonori; Min, Xiao; Li, Xiao; Hasegawa, Ena; Sakaguchi, Ei

    2015-01-01

    The present study was conducted to determine the mechanism by which nitrogen (N) availability is improved by fructo-oligosaccharide (FOS) in guinea pigs. Adult male guinea pigs were fed a commercial pellet diet (50 g/day) with either 5% glucose or 5% FOS for 7 days in individual metabolism cages. After 7 days of feeding the diet, (15) N-urea was administered intravenously 1 h before slaughter under anesthesia. The amount and concentration of total, protein, bacterial, ammonia and urea N and the (15) N atom % excess were measured in blood, liver, gut contents and urine. The (15) N atom % excess of total and protein N, and the amount of total, protein and bacteria N and (15) N in the cecum were significantly increased by the consumption of FOS. Furthermore, the concentration and amount of short-chain fatty acids were significantly increased by the consumption of FOS. In contrast, the amount of urinary (15) N was significantly decreased by the consumption of FOS. These results suggest that consumption of FOS increases transfer of blood urea N into the large intestine for bacterial N synthesis, which is subsequently re-absorbed by cecotrophy, and contributes to the increase of N utilization in guinea pigs. © 2014 Japanese Society of Animal Science.

  2. Study and program plan for improved heavy duty gas turbine engine ceramic component development

    NASA Technical Reports Server (NTRS)

    Helms, H. E.

    1977-01-01

    Fuel economy in a commercially viable gas turbine engine was demonstrated through use of ceramic materials. Study results show that increased turbine inlet and generator inlet temperatures, through the use of ceramic materials, contribute the greatest amount to achieving fuel economy goals. Improved component efficiencies show significant additional gains in fuel economy.

  3. Modeling stream-bank erosion in the Southern Blue Ridge Mountains

    Treesearch

    James C. Rogers; David S. Leigh

    2013-01-01

    Deforestation, followed by soil erosion and subsequent deposition of alluvium in valleys, played a critical role in the formation of historical terraces in much of the Southern Blue Ridge Mountains. Such terraces add a significant amount of sediment to the tributaries of the region as streams laterally erode the terrace banks. This study examined the contribution of...

  4. Stability and Patterns of Classroom Quality in German Early Childhood Education and Care

    ERIC Educational Resources Information Center

    Kuger, Susanne; Kluczniok, Katharina; Kaplan, David; Rossbach, Hans-Guenther

    2016-01-01

    Many education systems worldwide have dedicated a significant amount of resources to improve quality levels in early childhood education and care. Research can contribute to this goal by providing information about conditions of high-quality education and care and reasons for changes in the quality provided to children. This study therefore…

  5. Low Data Drug Discovery with One-Shot Learning

    PubMed Central

    2017-01-01

    Recent advances in machine learning have made significant contributions to drug discovery. Deep neural networks in particular have been demonstrated to provide significant boosts in predictive power when inferring the properties and activities of small-molecule compounds (Ma, J. et al. J. Chem. Inf. Model.2015, 55, 263–27425635324). However, the applicability of these techniques has been limited by the requirement for large amounts of training data. In this work, we demonstrate how one-shot learning can be used to significantly lower the amounts of data required to make meaningful predictions in drug discovery applications. We introduce a new architecture, the iterative refinement long short-term memory, that, when combined with graph convolutional neural networks, significantly improves learning of meaningful distance metrics over small-molecules. We open source all models introduced in this work as part of DeepChem, an open-source framework for deep-learning in drug discovery (Ramsundar, B. deepchem.io. https://github.com/deepchem/deepchem, 2016). PMID:28470045

  6. The contribution of general cognitive abilities and number abilities to different aspects of mathematics in children.

    PubMed

    Träff, Ulf

    2013-10-01

    This study examined the relative contributions of general cognitive abilities and number abilities to word problem solving, calculation, and arithmetic fact retrieval in a sample of 134 children aged 10 to 13 years. The following tasks were administered: listening span, visual matrix span, verbal fluency, color naming, Raven's Progressive Matrices, enumeration, number line estimation, and digit comparison. Hierarchical multiple regressions demonstrated that number abilities provided an independent contribution to fact retrieval and word problem solving. General cognitive abilities contributed to problem solving and calculation. All three number tasks accounted for a similar amount of variance in fact retrieval, whereas only the number line estimation task contributed unique variance in word problem solving. Verbal fluency and Raven's matrices accounted for an equal amount of variance in problem solving and calculation. The current findings demonstrate, in accordance with Fuchs and colleagues' developmental model of mathematical learning (Developmental Psychology, 2010, Vol. 46, pp. 1731-1746), that both number abilities and general cognitive abilities underlie 10- to 13-year-olds' proficiency in problem solving, whereas only number abilities underlie arithmetic fact retrieval. Thus, the amount and type of cognitive contribution to arithmetic proficiency varies between the different aspects of arithmetic. Furthermore, how closely linked a specific aspect of arithmetic is to the whole number representation systems is not the only factor determining the amount and type of cognitive contribution in 10- to 13-year-olds. In addition, the mathematical complexity of the task appears to influence the amount and type of cognitive support. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. Working Mothers and Their Children. Facts on Working Women No. 89-3.

    ERIC Educational Resources Information Center

    Women's Bureau (DOL), Washington, DC.

    In 1988, 65% of mothers with children under the age of 18 were in the labor force. Regardless of marital status, mothers are very active in the labor force and contribute significantly to family income. On average, female-headed households earned 56% of the amount married-couple families earn. Families maintained by women represented 52% of all…

  8. A global meta-analysis on the impact of management practices on net global warming potential and greenhouse gas intensity from cropland soils

    USDA-ARS?s Scientific Manuscript database

    Agricultural practices contribute significant amount of greenhouse gas (GHG) emissions, but little is known about their effects on net global warming potential (GWP) and greenhouse gas intensity (GHGI) that account for all sources and sinks of carbon dioxide emissions per unit area or crop yield. Se...

  9. Post-Primary Education and Energy Literacy: An Analysis of the Potential for Geography Curricula to Contribute to Australian Students' Energy Literacy

    ERIC Educational Resources Information Center

    Maddock, Brad; Kriewaldt, Jeana

    2014-01-01

    Unparalleled amounts of energy derived from fossil fuels now drive societies and shape people's worldviews. Geography's unique perspectives have significant potential to expand understandings of the effects of production and consumption of energy by drawing on the concept of sustainability using an integrated systems approach. As citizens' energy…

  10. How neglect and punitiveness influence emotion knowledge.

    PubMed

    Sullivan, Margaret Wolan; Carmody, Dennis P; Lewis, Michael

    2010-06-01

    To explore whether punitive parenting styles contribute to early-acquired emotion knowledge deficits observable in neglected children, we observed 42 preschool children's emotion knowledge, expression recognition time, and IQ. The children's mothers completed the Parent-Child Conflict Tactics Scales to assess the recent use of three types of discipline strategies (nonviolent, physically punitive, and psychological aggression), as well as neglectful parenting. Fifteen of the children were identified as neglected by Child Protective Services (CPS) reports; 27 children had no record of CPS involvement and served as the comparison group. There were no differences between the neglect and comparison groups in the demographic factors of gender, age, home language, minority status, or public assistance, nor on IQ. Hierarchical multiple regression modeling showed that neglect significantly predicted emotion knowledge. The addition of IQ contributed a significant amount of additional variance to the model and maintained the fit. Adding parental punitiveness in the final stage contributed little additional variance and did not significantly improve the fit. Thus, deficits in children's emotion knowledge may be due primarily to lower IQ or neglect. IQ was unrelated to speed of emotion recognition. Punitiveness did not directly contribute to emotion knowledge deficits but appeared in exploratory analysis to be related to speed of emotion recognition.

  11. Colonization and development of stream communities across a 200-year gradient in Glacier Bay National Park, Alaska

    USGS Publications Warehouse

    Milner, Alexander M.; Knudsen, E. Eric; Soiseth, Chad; Robertson, Anne L.; Schell, Don; Phillips, Ian T.; Magnusson, Katrina

    2000-01-01

    In May 1997, physical and biological variables were studied in 16 streams of different ages and contrasting stages of development following glacial recession in Glacier Bay National Park, southeast Alaska. The number of microcrustacean and macroinvertebrate taxa and juvenile fish abundance and diversity were significantly greater in older streams. Microcrustacean diversity was related to the amount of instream wood and percent pool habitat, while the number of macroinvertebrate taxa was related to bed stability, amount of instream wood, and percent pool habitat. The percent contribution of Ephemeroptera to stream benthic communities increased significantly with stream age and the amount of coarse benthic organic matter. Juvenile Dolly Varden (Salvelinus malma) were dominant in the younger streams, but juvenile coho salmon (Oncorhynchus kisutch) abundance was greater in older streams associated with increased pool habitat. Upstream lakes significantly influenced channel stability, percent Chironomidae, total macroinvertebrate and meiofaunal abundance, and percent fish cover. Stable isotope analyses indicated nitrogen enrichment from marine sources in macroinvertebrates and juvenile fish in older streams with established salmon runs. The findings are encapsulated in a conceptual summary of stream development that proposes stream assemblages to be determined by direct interactions with the terrestrial, marine, and lake ecosystems.

  12. Effects of hydrogen sulfide on high glucose-induced glomerular podocyte injury in mice

    PubMed Central

    Liu, Ye; Zhao, Huichen; Qiang, Ye; Qian, Guanfang; Lu, Shengxia; Chen, Jicui; Wang, Xiangdong; Guan, Qingbo; Liu, Yuantao; Fu, Yuqin

    2015-01-01

    The aim of this study was to assess the effects of hydrogen sulfide on high glucose-induced mouse podocyte (MPC) injury and the underlying mechanisms. Mouse podocytes were randomly divided into 4 groups, including high glucose (HG), normal glucose (NG), normal glucose + DL-propargylglycine (PPG), and high glucose + NaHS (HG + NaHS) groups for treatment. Then, ZO-2, nephrin, β-catenin, and cystathionine γ-lyase (CSE) protein expression levels were determined by western blot. We found that high glucose significantly reduced nephrin, ZO-2, and CSE expression levels (P<0.05), and overtly elevated β-catenin amounts (P<0.05), in a time-dependent manner. Likewise, PPG at different concentrations in normal glucose resulted in significantly lower CSE, ZO-2, and nephrin levels (P<0.05), and increased β-catenin amounts (P<0.05). Interestingly, significantly increased ZO-2 and nephrin levels, and overtly reduced β-catenin amounts were observed in the HG + NaHS group compared with HG treated cells (P<0.01). Compared with NG treated cells, decreased ZO-2 and nephrin levels and higher β-catenin amounts were obtained in the HG + NaHS group. In conclusion,CSE downregulation contributes to hyperglycemia induced podocyte injury, which is alleviated by exogenous H2S possibly through ZO-2 upregulation and the subsequent suppression of Wnt/β-catenin pathway. PMID:26261567

  13. 11 CFR 9008.12 - Repayments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... notify the national committee, and the national committee shall pay to the Secretary an amount equal to... committee shall pay to the Secretary an amount equal to the amount specified. (3) Excessive contributions... national committee shall pay to the Secretary an amount equal to the amount specified. (4) Improper usage...

  14. Properties of Residue from Olive Oil Extraction as a Raw Material for Sustainable Construction Materials. Part I: Physical Properties

    PubMed Central

    Díaz-García, Almudena; Martínez-García, Carmen; Cotes-Palomino, Teresa

    2017-01-01

    Action on climate, the environment, and the efficient use of raw materials and resources are important challenges facing our society. Against this backdrop, the construction industry must adapt to new trends and environmentally sustainable construction systems, thus requiring lines of research aimed at keeping energy consumption in new buildings as low as possible. One of the main goals of this research is to efficiently contribute to reducing the amount of residue from olive oil extraction using a two-phase method. This can be achieved by producing alternative structural materials to be used in the construction industry by means of a circular economy. The technical feasibility of adding said residue to ceramic paste was proven by analyzing the changes produced in the physical properties of the paste, which were then compared to the properties of the reference materials manufactured with clay without residue. Results obtained show that the heating value of wet pomace can contribute to the thermal needs of the sintering process, contributing 30% of energy in pieces containing 3% of said material. Likewise, adding larger amounts of wet pomace to the clay body causes a significant decrease in bulk density values. PMID:28772461

  15. Global Labour Mobility and Mutual Recognition of Skills and Qualifications: European Union and Australia/New Zealand Perspectives. Working Paper No. 56

    ERIC Educational Resources Information Center

    Shah, Chandra; Long, Michael

    2004-01-01

    The labour market is one the most significant markets in modern economies. Today labour embodies increasing amounts of human capital in the form of skills, talents and knowledge. Migration of workers between regions and countries can contribute to efficiency. People are moving from areas in which they are underemployed or unemployed to areas in…

  16. The Role of Mental Health Professionals Contributes to Mental Health Promotion and Prevention: Innovative Programmes in Serbia

    ERIC Educational Resources Information Center

    Milovancevic, Milica Pejovic; Jovicic, Milica

    2013-01-01

    It has been estimated that 9 to 13% of children and adolescents have a mental disorder that causes significant functioning impairment and that only one fifth of those who need mental health services actually receive them. The majority of children and adolescents are enrolled in schools, where they spend a considerable amount of time, and this is…

  17. Intra-plaque production of platelet-activating factor correlates with neoangiogenesis in human carotid atherosclerotic lesions.

    PubMed

    Lupia, Enrico; Pucci, Angela; Peasso, Paolo; Merlo, Maurizio; Baron, Paolo; Zanini, Cristina; Del Sorbo, Lorenzo; Rizea-Savu, Simona; Silvestro, Luigi; Forni, Marco; Emanuelli, Giorgio; Camussi, Giovanni; Montrucchio, Giuseppe

    2003-09-01

    Platelet-activating factor (PAF) is a phospholipid mediator synthesized by activated inflammatory and endothelial cells. Recently PAF has been shown to contribute to neoangiogenesis in several experimental models. Here we evaluated the presence of PAF and its potential role in neovascularization within human atherosclerotic plaques. The amount of PAF extracted from 18 carotid plaques (266.65+/-40.07 pg/100 mg dry tissue; mean +/- SE) was significantly higher than that extracted from 18 normal arterial specimens (6 from carotid artery and 12 from aorta) (4.72+/-2.31 pg/100 mg dry tissue; mean +/- SE). The levels of PAF significantly correlated with the infiltration of CD68-positive monocytes and the extent of neovascularization, detected as von Willebrand Factor-positive cells. The amount of PAF also correlated with the area occupied by TNF-alpha-expressing cells. The absence of enhanced level of PAF in the circulation of atherosclerotic patients suggests a local production of this mediator within the plaque. The lipid extracts of atherosclerotic plaques containing high levels of PAF-bioactivity, but not those of control arteries, were angiogenic in a murine Matrigel model. WEB 2170, a specific PAF receptor antagonist, significantly prevented angiogenesis induced by the lipid extracts of atherosclerotic plaques. Our results indicate a local production of PAF within the atherosclerotic plaques and suggest that it may contribute to intra-plaque neoangiogenesis.

  18. Theory of mind in schizophrenia: correlation with clinical symptomatology, emotional recognition and ward behavior.

    PubMed

    Lee, Woo Kyeong; Kim, Yong Kyu

    2013-09-01

    Several studies have suggested the presence of a theory of mind (ToM) deficit in schizophrenic disorders. This study examined the relationship of emotion recognition, theory of mind, and ward behavior in patients with schizophrenia. Fifty-five patients with chronic schizophrenia completed measures of emotion recognition, ToM, intelligence, Positive and Negative Syndrome Scale (PANSS) and Nurse's Observation Scale for Inpatient Evaluation (NOSIE). Theory of mind sum score correlated significantly with IQ, emotion recognition, and ward behavior. Ward behavior was linked to the duration of the illness, and even more so to theory of mind deficits. Theory of mind contributed a significant proportion of the amount of variance to explain social behavior on the ward. Considering our study results, impaired theory of mind contributes significantly to the understanding of social competence in patients with schizophrenia. Copyright © 2012 Wiley Publishing Asia Pty Ltd.

  19. The Synthesis of 44Ti and 56Ni in Massive Stars

    NASA Astrophysics Data System (ADS)

    Chieffi, Alessandro; Limongi, Marco

    2017-02-01

    We discuss the influence of rotation on the combined synthesis of {}44{Ti} and {}56{Ni} in massive stars. While {}56{Ni} is significantly produced by both complete and incomplete explosive Si burning, {}44{Ti} is mainly produced by complete explosive Si burning, with a minor contribution (in standard non-rotating models) from incomplete explosive Si burning and O burning (both explosive and hydrostatic). We find that, in most cases, the thickness of the region exposed to incomplete explosive Si burning increases in rotating models (initial velocity, v ini = 300 km s-1) and since {}56{Ni} is significantly produced in this zone, the fraction of mass coming from the complete explosive Si burning zone necessary to get the required amount of {}56{Ni} reduces. Therefore the amount of {}44{Ti} ejected for a given fixed amount of {}56{Ni} decreases in rotating models. However, some rotating models at [Fe/H] = -1 develop a very extended O convective shell in which a consistent amount of {}44{Ti} is formed, preserved, and ejected in the interstellar medium. Hence a better modeling of the thermal instabilities (convection) in the advanced burning phases together with a critical analysis of the cross sections of the nuclear reactions operating in O burning are relevant for the understanding of the synthesis of {}44{Ti}.

  20. Strategies for enhancing the phytoremediation of cadmium-contaminated agricultural soils by Solanum nigrum L.

    PubMed

    Ji, Puhui; Sun, Tieheng; Song, Yufang; Ackland, M Leigh; Liu, Yang

    2011-03-01

    Field trials contribute practical information towards the development of phytoremediation strategies that cannot be provided by laboratory tests. We conducted field experiments utilizing the Cd hyperaccumulator plant Solanum nigrum L., on farmland contaminated with 1.91 mg kg(-1) Cd in the soil. Our study showed that S. nigrum has a relatively high biomass. Planting density had a significant effect on the plant biomass and thus on overall Cd accumulation. For double harvesting, an optimal cutting position influenced the amount of Cd extracted from soils. Double cropping was found to significantly increase the amount of Cd extracted by S. nigrum. Fertilizing had no significant effect on plant biomass or on the Cd remediation of the soil over the short-term period. Our study indicates that S. nigrum can accumulate Cd from soils where the concentrations are relatively low, and thus has application for use in decontamination of slightly to moderately Cd-contaminated soil. Copyright © 2010 Elsevier Ltd. All rights reserved.

  1. 26 CFR 1.402A-1 - Designated Roth Accounts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... gross income as an amount allocable to investment in the contract is determined under section 72(e)(8... portion not includible in gross income as an amount allocable to investment in the contract is determined... preceding, however, a contribution that is returned as an excess deferral or excess contribution does not...

  2. Contributions of the Medial Temporal Lobe to Declarative Memory Retrieval: Manipulating the Amount of Contextual Retrieval

    ERIC Educational Resources Information Center

    Tendolkar, Indira; Arnold, Jennifer; Petersson, Karl Magnus; Weis, Susanne; Brockhaus-Dumke, Anke; van Eijndhoven, Philip; Buitelaar, Jan; Fernandez, Guillen

    2008-01-01

    We investigated how the hippocampus and its adjacent mediotemporal structures contribute to contextual and noncontextual declarative memory retrieval by manipulating the amount of contextual information across two levels of the same contextual dimension in a source memory task. A first analysis identified medial temporal lobe (MTL) substructures…

  3. Termites in the hominin diet: a meta-analysis of termite genera, species and castes as a dietary supplement for South African robust australopithecines.

    PubMed

    Lesnik, Julie J

    2014-06-01

    Termite foraging by chimpanzees and present-day modern humans is a well-documented phenomenon, making it a plausible hypothesis that early hominins were also utilizing this resource. Hominin termite foraging has been credited by some to be the explanation for the unexpected carbon isotope signatures present in South African hominin teeth, which suggest the diet was different from that of extant non-human great apes, consisting of a significant amount of resources that are not from woody-plants. Grass-eating termites are one potential resource that could contribute to the carbon signature. However, not all termites eat grasses, and in fact, the termites that are most widely consumed by chimpanzees and by many present-day human populations at best have a mixed diet that includes small amounts of grasses. Here I review the ecology of termites and how it affects their desirability as a food resource for hominins, and conduct a meta-analysis of nutritional values for various genera, species and castes from the literature. Termites are very diverse, even within species, and this variability affects both their carbon signatures and nutritional value, hindering generalizations regarding the contribution of termites to the hominin diet. It is concluded here that a combination of soldiers and alates of the genus Macrotermes be used to model the insectivory component of the Plio-Pleistocene hominin diet due to their significant amounts of energy-yielding nutrients and potential role as a critical resource for supporting larger-brained hominins. Copyright © 2014. Published by Elsevier Ltd.

  4. The electrical conductivities of the DSS-13 beam-waveguide antenna shroud material and other antenna reflector surface materials

    NASA Technical Reports Server (NTRS)

    Otoshi, T. Y.; Franco, M. M.; Reilly, H. F., Jr.

    1992-01-01

    A significant amount of noise temperature can potentially be generated by currently unknown dissipative losses in the beam waveguide (BWG) shroud. The amount of noise temperature contribution from this source is currently being studied. In conjunction with this study, electrical conductivity measurements were made on samples of the DSS-13 BWG shroud material at 8.420 GHz. The effective conductivities of unpainted and painted samples of the BWG shroud were measured to be 0.01 x 10(exp 7) and 0.0036 x 10(exp 7) mhos/m, respectively. This value may be compared with 5.66 x 10(exp 7) mhos/m for high conductivity copper.

  5. The effects of physical activity on impulsive choice: Influence of sensitivity to reinforcement amount and delay

    PubMed Central

    Strickland, Justin C.; Feinstein, Max A.; Lacy, Ryan T.; Smith, Mark A.

    2016-01-01

    Impulsive choice is a diagnostic feature and/or complicating factor for several psychological disorders and may be examined in the laboratory using delay-discounting procedures. Recent investigators have proposed using quantitative measures of analysis to examine the behavioral processes contributing to impulsive choice. The purpose of this study was to examine the effects of physical activity (i.e., wheel running) on impulsive choice in a single-response, discrete-trial procedure using two quantitative methods of analysis. To this end, rats were assigned to physical activity or sedentary groups and trained to respond in a delay-discounting procedure. In this procedure, one lever always produced one food pellet immediately, whereas a second lever produced three food pellets after a 0, 10, 20, 40, or 80-second delay. Estimates of sensitivity to reinforcement amount and sensitivity to reinforcement delay were determined using (1) a simple linear analysis and (2) an analysis of logarithmically transformed response ratios. Both analyses revealed that physical activity decreased sensitivity to reinforcement amount and sensitivity to reinforcement delay. These findings indicate that (1) physical activity has significant but functionally opposing effects on the behavioral processes that contribute to impulsive choice and (2) both quantitative methods of analysis are appropriate for use in single-response, discrete-trial procedures. PMID:26964905

  6. Lead induced changes in growth and micronutrient uptake of Jatropha curcas L.

    PubMed

    Shu, Xiao; Zhang, QuanFa; Wang, WeiBo

    2014-11-01

    Effects of lead treatment on growth and micronutrient uptake in Jatropha curcas L. seedlings were assessed by means of microcosm experiments. Results suggested that superoxide dismutase (SOD) activity increased with increasing lead concentration. There was significant positive correlation between lead treatment concentration and SOD and peroxidase activity. Catalase activity was initiated under lower lead stress but, was inhibited under higher lead exposure. Lead had a stimulating effect on seedlings height and leaf area at lower lead concentrations. The J. curcas can accumulate higher amounts of available lead from soil but can translocate only low amounts to the shoots. Results indicating SOD and peroxidase activity in J. curcas seedlings played an important role in resisting the oxidative stress induced by lead. The addition of lead significantly increased the content of zinc in plant tissue and enhanced the transport of iron from roots to shoots but contributed to a decrease in measured copper, iron, and manganese content.

  7. Effect of Bio based rejuvenator on mix design, Energy consumption and GHG Emission of High RAP Mixture

    NASA Astrophysics Data System (ADS)

    Abdullahi Ahmad, Kabiru; Ezree Abdullah, Mohd; Hassan, Norhidayah Abdul; Usman, Nura; Hassan, Mohd Rosli Mohd; Bilema, Munder A. M.; Modibbo Saeed, Saeed; Batari, Ahmad

    2018-04-01

    Concerns about the cost, availability, and environmental impact of using petroleum-based materials have led to increased usage of reclaimed asphalt pavement (RAP). Mean-while, the demand of the road industry to decrease the energy consumptions and reduce the release of greenhouse gases as well as other harmful gases, which cause serious air pollution has increased due to the amount of energy consumed is a major component of pavement construction that significantly contributes to the total cost. This paper evaluates the effects of Biobased rejuvenator known as JCO on the required heat energy and the amount of CO2 produced to increase the temperature of RAP and virgin aggregates and one binder from 25C to the point of mixing. The results showed that incorporating Biobased rejuvenator (JCO) can potentially reduce the required heat energy and amount of greenhouse gas produced by RAP and virgin, respectively.

  8. Tectonic Evolution and Midplate Volcanism in the South Pacific

    DTIC Science & Technology

    1999-02-01

    documented in the South- ern Austral Island region of the South Pacific. A twelve degree clock- wise change in Pacific-Farallon relative motion occurred...and spreading fabric orientation. At the southeastern end of the Cook-Austral Island chain, multiple episodes of volcanism have left a diverse...in the flexural moat of the Austral Islands , probably associated with Austral Islands volcanism, which may contribute a significant amount of

  9. Source-Receptor Relationship Analysis of the Atmospheric Deposition of PAHs Subject to Long-Range Transport in Northeast Asia.

    PubMed

    Inomata, Yayoi; Kajino, Mizuo; Sato, Keiichi; Kurokawa, Junichi; Tang, Ning; Ohara, Toshimasa; Hayakawa, Kazuichi; Ueda, Hiromasa

    2017-07-18

    The source-receptor relationship analysis of PAH deposition in Northeast Asia was investigated using an Eulerian regional-scale aerosol chemical transport model. Dry deposition (DD) of PAH was controlled by wind flow patterns, whereas wet deposition (WD) depended on precipitation in addition to wind flow patterns. The contribution of WD was approximately 50-90% of the total deposition, except during winter in Northern China (NCHN) and Eastern Russia (ERUS) because of the low amount of precipitation. The amount of PAH deposition showed clear seasonal variation and was high in winter and low in summer in downwind (South Korea, Japan) and oceanic-receptor regions. In the downwind region, the contributions from NCHN (WD 28-52%; DD 54-55%) and Central China (CCHN) (WD 43-65%; DD 33-38%) were large in winter, whereas self-contributions (WD 20-51%; DD 79-81%) were relatively high in summer. In the oceanic-receptor region, the deposition amount decreased with distance from the Asian continent. The amount of DD was strongly influenced by emissions from neighboring domains. The contributions of WD from NCHN (16-20%) and CCHN (28-35%) were large. The large contributions from China in summer to the downwind region were linked to vertical transport of PAHs over the Asian continent associated with convection.

  10. Surface antigens contribute differently to the pathophysiological features in serotype K1 and K2 Klebsiella pneumoniae strains isolated from liver abscesses.

    PubMed

    Yeh, Kuo-Ming; Chiu, Sheng-Kung; Lin, Chii-Lan; Huang, Li-Yueh; Tsai, Yu-Kuo; Chang, Jen-Chang; Lin, Jung-Chung; Chang, Feng-Yee; Siu, Leung-Kei

    2016-01-01

    The virulence role of surface antigens in a single serotype of Klebsiella pneumoniae strain have been studied, but little is known about whether their contribution will vary with serotype. To investigate the role of K and O antigen in hyper-virulent strains, we constructed O and K antigen deficient mutants from serotype K1 STL43 and K2 TSGH strains from patients with liver abscess, and characterized their virulence in according to the abscess formation and resistance to neutrophil phagocytosis, serum, and bacterial clearance in liver. Both of K1 and K2-antigen mutants lost their wildtype resistance to neutrophil phagocytosis and hepatic clearance, and failed to cause abscess formation. K2-antigen mutant became serum susceptible while K1-antigen mutant maintained its resistance to serum killing. The amount of glucuronic acid, indicating the amount of capsular polysaccharide (CPS, K antigen), was inversed proportional to the rate of phagocytosis. O-antigen mutant of serotype K1 strains had significantly more amount of CPS, and more resistant to neutrophil phagocytosis than its wildtype counterpart. O-antigen mutants of serotype K1 and K2 strains lost their wildtype serum resistance, and kept resistant to neutrophil phagocytosis. While both mutants lacked the same O1 antigen, O-antigen mutant of serotype K1 became susceptible to liver clearance and cause mild abscess formation, but its serotype K2 counterpart maintained these wildtype virulence. We conclude that the contribution of surface antigens to virulence of K. pneumoniae strains varies with serotypes.

  11. How Neglect and Punitiveness Influence Emotion Knowledge

    PubMed Central

    Sullivan, Margaret Wolan; Carmody, Dennis P.

    2010-01-01

    To explore whether punitive parenting styles contribute to early-acquired emotion knowledge deficits observable in neglected children, we observed 42 preschool children’s emotion knowledge, expression recognition time, and IQ. The children’s mothers completed the Parent–Child Conflict Tactics Scales to assess the recent use of three types of discipline strategies (nonviolent, physically punitive, and psychological aggression), as well as neglectful parenting. Fifteen of the children were identified as neglected by Child Protective Services (CPS) reports; 27 children had no record of CPS involvement and served as the comparison group. There were no differences between the neglect and comparison groups in the demographic factors of gender, age, home language, minority status, or public assistance, nor on IQ. Hierarchical multiple regression modeling showed that neglect significantly predicted emotion knowledge. The addition of IQ contributed a significant amount of additional variance to the model and maintained the fit. Adding parental punitiveness in the final stage contributed little additional variance and did not significantly improve the fit. Thus, deficits in children’s emotion knowledge may be due primarily to lower IQ or neglect. IQ was unrelated to speed of emotion recognition. Punitiveness did not directly contribute to emotion knowledge deficits but appeared in exploratory analysis to be related to speed of emotion recognition. PMID:20099078

  12. Social factors of mental disorder and suicide in Japan-for understanding circumstance of suicides in each prefecture-.

    PubMed

    Motohashi, Hideyuki; Fujimoto, Atsuko; Sakane, Toshiyasu; Yamamoto, Akira; Yano, Yoshitaka

    2013-01-01

    In recent years there have been over 30000 suicides annually in Japan. This is one of the most serious problems for Japanese society. Because mental disorder is closely associated with suicide, factors related to the increase in mental disorders and suicides should be clarified. In this study, various data regarding social factors were evaluated to assess the correlation of the number of patients with mental disorders and suicides among the 47 prefectures of Japan. Various data regarding social factors, such as income, savings, or rate of divorce, were obtained from the database of the Ministry of Health, Labour and Welfare of Japan. Among the factors, the annual income and the amount of savings were significantly correlated with the number of patients with mental disorder. On the other hand, while the annual income did not have a significant correlation with suicides, the amount of savings had a significant correlation with suicides. In conclusion, the annual income and amount of savings may both be one of the important factors involved in mental disorders, and the savings may also be a factor affecting suicides. These analyses are valuable in helping to clarify the causes of mental disease, and can hopefully contribute to the health and welfare of Japanese.

  13. Influence of lipids in the generation of phenylacetaldehyde in wort-related model systems.

    PubMed

    Gallardo, Emerenciana; De Schutter, David P; Zamora, Rosario; Derdelinckx, Guy; Delvaux, Freddy R; Hidalgo, Francisco J

    2008-05-14

    The effect of lipids on the formation of the Strecker aldehyde phenylacetaldehyde during wort boiling was studied to determine the role that small changes in the lipid content of the wort have in the production of significant flavor compounds in beer. Wort was treated with 0-2.77 mmol per liter of glucose, linoleic acid, or 2,4-decadienal and heated at 60-98 degrees C for 1 h. After this time, the amount of the Strecker aldehyde phenylacetaldehyde increased in the samples treated with linoleic acid or decadienal but not in the samples treated with glucose. Thus, the amount of phenylacetaldehyde produced in the presence of linoleic acid was 1.1-2.5 times the amount of the Strecker aldehyde produced in the control wort, and this amount increased to 3.6-4.6 times when decadienal was employed. The higher reactivity of decadienal than linoleic acid for this reaction decreased with temperature and was related to the oxidation of linoleic acid that occurred to a higher extent at higher temperatures. The above results suggest that lipids can contribute to the formation of Strecker aldehydes during wort boiling and that changes in the lipid content of the wort will produce significant changes in the formation of Strecker aldehydes in addition to other well-known consequences in beer quality and yeast metabolism. On the other hand, because of the high glucose content in wort, small changes in its content are not expected to affect the amount of Strecker aldehydes produced.

  14. ICT reuse in socio-economic enterprises

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ongondo, F.O., E-mail: f.ongondo@soton.ac.uk; Williams, I.D.; Dietrich, J.

    Highlights: • We analyse ICT equipment reuse operations of socio-economic enterprises. • Most common ICT products dealt with are computers and related equipment. • In the UK in 2010, ∼143,750 appliances were reused. • Marketing and legislative difficulties are the common hurdles to reuse activities. • Socio-economic enterprises can significantly contribute to resource efficiency. - Abstract: In Europe, socio-economic enterprises such as charities, voluntary organisations and not-for-profit companies are involved in the repair, refurbishment and reuse of various products. This paper characterises and analyses the operations of socio-economic enterprises that are involved in the reuse of Information and Communication Technologymore » (ICT) equipment. Using findings from a survey, the paper specifically analyses the reuse activities of socio-economic enterprises in the UK from which Europe-wide conclusions are drawn. The amount of ICT products handled by the reuse organisations is quantified and potential barriers and opportunities to their operations are analysed. By-products from reuse activities are discussed and recommendations to improve reuse activities are provided. The most common ICT products dealt with by socio-economic enterprises are computers and related equipment. In the UK in 2010, an estimated 143,750 appliances were reused. However, due to limitations in data, it is difficult to compare this number to the amount of new appliances that entered the UK market or the amount of waste electrical and electronic equipment generated in the same period. Difficulties in marketing products and numerous legislative requirements are the most common barriers to reuse operations. Despite various constraints, it is clear that organisations involved in reuse of ICT could contribute significantly to resource efficiency and a circular economy. It is suggested that clustering of their operations into “reuse parks” would enhance both their profile and their products. Reuse parks would also improve consumer confidence in and subsequently sales of the products. Further, it is advocated that industrial networking opportunities for the exchange of by-products resulting from the organisations’ activities should be investigated. The findings make two significant contributions to the current literature. One, they provide a detailed insight into the reuse operations of socio-economic enterprises. Previously unavailable data has been presented and analysed. Secondly, new evidence about the by-products/materials resulting from socio-economic enterprises’ reuse activities has been obtained. These contributions add substantially to our understanding of the important role of reuse organisations.« less

  15. Brown carbon and internal mixing in biomass burning particles

    PubMed Central

    Lack, Daniel A.; Langridge, Justin M.; Bahreini, Roya; Cappa, Christopher D.; Middlebrook, Ann M.; Schwarz, Joshua P.

    2012-01-01

    Biomass burning (BB) contributes large amounts of black carbon (BC) and particulate organic matter (POM) to the atmosphere and contributes significantly to the earth’s radiation balance. BB particles can be a complicated optical system, with scattering and absorption contributions from BC, internal mixtures of BC and POM, and wavelength-dependent absorption of POM. Large amounts of POM can also be externally mixed. We report on the unique ability of multi-wavelength photo-acoustic measurements of dry and thermal-denuded absorption to deconstruct this complicated wavelength-dependent system of absorption and mixing. Optical measurements of BB particles from the Four Mile Canyon fire near Boulder, Colorado, showed that internal mixtures of BC and POM enhanced absorption by up to 70%. The data supports the assumption that the POM was very weakly absorbing at 532 nm. Enhanced absorption at 404 nm was in excess of 200% above BC absorption and varied as POM mass changed, indicative of absorbing POM. Absorption by internal mixing of BC and POM contributed 19( ± 8)% to total 404-nm absorption, while BC alone contributed 54( ± 16)%. Approximately 83% of POM mass was externally mixed, the absorption of which contributed 27( ± 15)% to total particle absorption (at 404 nm). The imaginary refractive index and mass absorption efficiency (MAE) of POM at 404 nm changed throughout the sampling period and were found to be 0.007 ± 0.005 and 0.82 ± 0.43 m2 g-1, respectively. Our analysis shows that the MAE of POM can be biased high by up to 50% if absorption from internal mixing of POM and BC is not included. PMID:22927381

  16. Brown carbon and internal mixing in biomass burning particles.

    PubMed

    Lack, Daniel A; Langridge, Justin M; Bahreini, Roya; Cappa, Christopher D; Middlebrook, Ann M; Schwarz, Joshua P

    2012-09-11

    Biomass burning (BB) contributes large amounts of black carbon (BC) and particulate organic matter (POM) to the atmosphere and contributes significantly to the earth's radiation balance. BB particles can be a complicated optical system, with scattering and absorption contributions from BC, internal mixtures of BC and POM, and wavelength-dependent absorption of POM. Large amounts of POM can also be externally mixed. We report on the unique ability of multi-wavelength photo-acoustic measurements of dry and thermal-denuded absorption to deconstruct this complicated wavelength-dependent system of absorption and mixing. Optical measurements of BB particles from the Four Mile Canyon fire near Boulder, Colorado, showed that internal mixtures of BC and POM enhanced absorption by up to 70%. The data supports the assumption that the POM was very weakly absorbing at 532 nm. Enhanced absorption at 404 nm was in excess of 200% above BC absorption and varied as POM mass changed, indicative of absorbing POM. Absorption by internal mixing of BC and POM contributed 19( ± 8)% to total 404-nm absorption, while BC alone contributed 54( ± 16)%. Approximately 83% of POM mass was externally mixed, the absorption of which contributed 27( ± 15)% to total particle absorption (at 404 nm). The imaginary refractive index and mass absorption efficiency (MAE) of POM at 404 nm changed throughout the sampling period and were found to be 0.007 ± 0.005 and 0.82 ± 0.43 m(2) g(-1), respectively. Our analysis shows that the MAE of POM can be biased high by up to 50% if absorption from internal mixing of POM and BC is not included.

  17. Periodontal disease level-butyric acid amounts locally administered in the rat gingival mucosa induce ER stress in the systemic blood.

    PubMed

    Cueno, Marni E; Saito, Yuko; Ochiai, Kuniyasu

    2016-05-01

    Periodontal diseases have long been postulated to contribute to systemic diseases and, likewise, it has been proposed that periodontal disease treatment may ameliorate certain systemic diseases. Short-chain fatty acids (SCFA) are major secondary metabolites produced by oral anaerobic bacteria and, among the SCFAs, butyric acid (BA) in high amounts contribute to periodontal disease development. Periodontal disease level-butyric acid (PDL-BA) is found among patients suffering from periodontal disease and has previously shown to induce oxidative stress, whereas, oxidative stress is correlated to endoplasmic reticulum (ER) stress. This would imply that PDL-BA may likewise stimulate ER stress, however, this was never elucidated. A better understanding of the correlation between PDL-BA and systemic ER stress stimulation could shed light on the possible systemic effects of PDL-BA-related periodontal diseases. Here, PDL-BA was injected into the gingival mucosa and the systemic blood obtained from the rat jugular was collected at 0, 15, 60, and 180 min post-injection. Collected blood samples were purified and only the blood cytosol was used throughout this study. Subsequently, we measured blood cytosolic GADD153, Ca(2+), representative apoptotic and inflammatory caspases, and NF-κB amounts. We found that PDL-BA presence increased blood cytosolic GADD153 and Ca(2+) amounts. Moreover, we observed that blood cytosolic caspases and NF-κB were activated only at 60 and 180 min post-injection in the rat gingival mucosa. This suggests that PDL-BA administered through the gingival mucosa may influence the systemic blood via ER stress stimulation and, moreover, prolonged PDL-BA retention in the gingival mucosa may play a significant role in ER stress-related caspase and NF-κB activation. In a periodontal disease scenario, we propose that PDL-BA-related ER stress stimulation leading to the simultaneous activation of apoptosis and inflammation may contribute to periodontal disease pathogenesis. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Daily physical activity and its contribution to the health-related quality of life of ambulatory individuals with chronic stroke

    PubMed Central

    2010-01-01

    Background Participation in daily physical activity (PA) post-stroke has not previously been investigated as a possible explanatory variable of health-related quality of life (HRQL). The aims were 1) to determine the contribution of daily PA to the HRQL of individuals with chronic stroke and 2) to assess the relationship between the functional ability of these individuals to the amount of daily PA. Methods The amount of daily PA of forty adults with chronic stroke (mean age 66.5 ± 9.6 years) was monitored using two measures. Accelerometers (Actical) were worn on the hip for three consecutive days in conjunction with a self-report questionnaire [the PA Scale for Individuals with Physical Disabilities (PASIPD)]. The daily physical activity was measured as the mean total accelerometer activity counts/day and the PASIPD scores as the metabolic equivalent (MET) hr/day. HRQL was assessed by the Physical and Mental composite scores of the Medical Outcomes Study Short-Form 36 (SF-36) in addition to the functional ability of the participants. Correlation and regression analyses were performed. Results After controlling for the severity of the motor impairment, the amount of daily PA, as assessed by the PASIPD and accelerometers, was found to independently contribute to 10-12% of the variance of the Physical Composite Score of the SF-36. No significant relationship was found between PA and the Mental Composite Score of the SF-36.The functional ability of the participants was found to be correlated to the amount of daily PA (r = 0.33 - 0.67, p < 0.01). Conclusion The results suggest that daily PA is associated with better HRQL (as assessed by the Physical composite score of the SF-36) for people living with stroke. Daily PA should be encouraged to potentially increase HRQL. Accelerometers in conjunction with a self-report questionnaire may provide important measures of PA which can be monitored and modified, and potentially influence HRQL. PMID:20682071

  19. Daily physical activity and its contribution to the health-related quality of life of ambulatory individuals with chronic stroke.

    PubMed

    Rand, Debbie; Eng, Janice J; Tang, Pei-Fang; Hung, Chihya; Jeng, Jiann-Shing

    2010-08-03

    Participation in daily physical activity (PA) post-stroke has not previously been investigated as a possible explanatory variable of health-related quality of life (HRQL). The aims were 1) to determine the contribution of daily PA to the HRQL of individuals with chronic stroke and 2) to assess the relationship between the functional ability of these individuals to the amount of daily PA. The amount of daily PA of forty adults with chronic stroke (mean age 66.5 +/- 9.6 years) was monitored using two measures. Accelerometers (Actical) were worn on the hip for three consecutive days in conjunction with a self-report questionnaire [the PA Scale for Individuals with Physical Disabilities (PASIPD)]. The daily physical activity was measured as the mean total accelerometer activity counts/day and the PASIPD scores as the metabolic equivalent (MET) hr/day. HRQL was assessed by the Physical and Mental composite scores of the Medical Outcomes Study Short-Form 36 (SF-36) in addition to the functional ability of the participants. Correlation and regression analyses were performed. After controlling for the severity of the motor impairment, the amount of daily PA, as assessed by the PASIPD and accelerometers, was found to independently contribute to 10-12% of the variance of the Physical Composite Score of the SF-36. No significant relationship was found between PA and the Mental Composite Score of the SF-36.The functional ability of the participants was found to be correlated to the amount of daily PA (r = 0.33 - 0.67, p < 0.01). The results suggest that daily PA is associated with better HRQL (as assessed by the Physical composite score of the SF-36) for people living with stroke. Daily PA should be encouraged to potentially increase HRQL. Accelerometers in conjunction with a self-report questionnaire may provide important measures of PA which can be monitored and modified, and potentially influence HRQL.

  20. Changes in core food intake among Australian children between 1995 and 2007.

    PubMed

    Rangan, A M; Kwan, J S L; Louie, J C Y; Flood, V M; Gill, T P

    2011-11-01

    To assess the changes in the consumption of core foods among Australian children between the 1995 National Nutrition Survey (1995 NNS) and the 2007 Australian National Children's Nutrition and Physical Activity Survey (2007 Children's Survey). Core food consumption was analysed using 24-h recall data from 2-16 year old children using the 1995 NNS (n=2435) and the 2007 Children's Survey (n=4380). Differences in percent consuming, amounts consumed and percent energy contribution were assessed. The consumption of core foods increased significantly between the 1995 and 2007 surveys, including per-capita consumption and percent energy contribution (both P0.001). Core foods contributed to 59% of energy intake in 1995 compared with 65% in 2007. The types of core foods consumed also changed during this time period with more children reporting eating healthy options such as wholemeal bread, reduced-fat milk, reduced-fat cheese and fruit in the 2007 Children's Survey. Conversely, the consumption of white bread, full-fat milk and low-fibre breakfast cereals was lower in 2007. Overall, reported dietary intake had improved from 1995 to 2007 among Australian children with an increase in the amounts of core foods consumed and healthier types of foods being chosen. Continued health-promotion activities and monitoring of food consumption are highly warranted.

  1. 26 CFR 1.401(m)-1 - Employee contributions and matching contributions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Employee contributions and matching.... § 1.401(m)-1 Employee contributions and matching contributions. (a) General nondiscrimination rules—(1... not satisfy section 401(a) for a plan year unless the amount of employee contributions and matching...

  2. The influence of fire on the radiocarbon signature and character of soil organic matter in the Siskiyou national forest, Oregon, USA

    Treesearch

    Katherine Heckman; John L. Campbell; Heath Powers; Beverly E. Law; Chris Swanston

    2013-01-01

    Forest fires contribute a significant amount of CO2 to the atmosphere each year, and CO2 emissions from fires are likely to increase under projected conditions of global climate change. In addition to volatilizing aboveground biomass and litter layers, forest fires have a profound effect on belowground carbon (C) pools and the cycling of soil organic matter as a whole...

  3. Applying Lean to the AC-130 Maintenance Process for the Royal Saudi Air Force

    DTIC Science & Technology

    2016-09-01

    inventory management. Quality Management Poor quality of maintenance contributes to rework , which is an obvious form of waste. It would be very...consequences of rework are very significant. Within the C-130 maintenance squadron, quality must be achieved through continual process improvements, rather...maintenance “product” quality by lowering measurable process outputs such as amount of rework , number of maintenance-induced failures, and so on. 71

  4. 5 CFR 1605.2 - Calculating, posting, and charging breakage.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... will calculate breakage on late contributions, makeup agency contributions, and loan payments as... is the breakage. (c) Posting contributions and loan payments. Makeup and late contributions, late... participant's account is greater than the dollar amount of the makeup or late contribution or late loan...

  5. Effects of yeast and bran on phytate degradation and minerals in rice bread.

    PubMed

    Kadan, R S; Phillippy, B Q

    2007-05-01

    Rice bread is a potential alternative to wheat bread for gluten-sensitive individuals. Incorporation of rice bran into bread made from white rice flour adds flavor but also phytic acid, which can reduce the bioavailability of minerals. Breads with varied amounts of defatted bran and yeast were prepared to determine their effects on the phytate and mineral contents of the bread. A completely randomized factorial design was used with bran levels of 3.7%, 7.3%, and 10.5% of the dry ingredients and yeast levels of 1.6%, 3.2%, and 4.7%. Increasing the amount of bran decreased the phytate degradation from 42% at the lowest level of bran to 10% at the highest, and the amount of yeast had no significant effect. The bran contributed substantial amounts of magnesium, iron, and zinc. Breads with the lowest level of bran had phytate-to-zinc molar ratios between 5 and 10, which suggest medium zinc bioavailability. Rice bread is a tasty and nutritious food that is a good dietary source of minerals for people who cannot tolerate wheat bread.

  6. Aztec cannibalism: an ecological necessity?

    PubMed

    de Montellano, B R

    1978-05-12

    It has been proposed that Aztec human sacrifice and cannibalism can best be explained as a response to population pressure and famine. The greatest amount of cannibalism, however, coincided with times of harvest, not with periods of scarcity, and is better explained as a thanksgiving. Tenochtitlan recevied large quantities of food tribute and engaged in intensive (chinampa) agriculture. These two sources alone would have provided enough to feed practically the entire population of the city. The Aztecs also consumed various animals and insects that were good protein sources. The amount of protein available from human sacrifice would not have made a significant contribution to the diet. Cannibalism was not motivated by starvation but by a belief that this was a way to commune with the gods.

  7. A theoretical study of alpha star populations in loaded nuclear emulsions

    USGS Publications Warehouse

    Senftle, F.E.; Farley, T.A.; Stieff, L.R.

    1954-01-01

    This theoretical study of the alpha star populations in loaded emulsions was undertaken in an effort to find a quantitative method for the analysis of less than microgram amounts of thorium in the presence of larger amounts of uranium. Analytical expressions for each type of star from each of the significantly contributing members of the uranium and thorium series as well as summation formulas for the whole series have been computed. The analysis for thorium may be made by determining the abundance of five-branched stars in a loaded nuclear emulsion and comparing of observed and predicted star populations. The comparison may also be used to check the half-lives of several members of the uranium and thorium series. ?? 1954.

  8. Hot/Wet Open Hole Compression Strength of Carbon/Epoxy Laminates for Launch Vehicle Applications

    NASA Technical Reports Server (NTRS)

    Nettles, Alan T.

    2009-01-01

    This Technical Memorandum examines the effects of heat and absorbed moisture on the open hole compression strength of carbon/epoxy laminates with the material and layup intended for the Ares I composite interstage. The knockdown due to temperature, amount of moisture absorbed, and the interaction between these two are examined. Results show that temperature is much more critical than the amount of moisture absorbed. The environmental knockdown factor was found to be low for this material and layup and thus obtaining a statistically significant number for this value needs to be weighed against a program s cost and schedule since basis values, damage tolerance, and safety factors all contribute much more to the overall knockdown factor.

  9. Extraction of intracellular protein from Chlorella pyrenoidosa using a combination of ethanol soaking, enzyme digest, ultrasonication and homogenization techniques.

    PubMed

    Zhang, Ruilin; Chen, Jian; Zhang, Xuewu

    2018-01-01

    Due to the rigid cell wall of Chlorella species, it is still challenging to effectively extract significant amounts of protein. Mass methods were used for the extraction of intracellular protein from microalgae with biological, mechanical and chemical approaches. In this study, based on comparison of different extraction methods, a new protocol was established to maximize extract amounts of protein, which was involved in ethanol soaking, enzyme digest, ultrasonication and homogenization techniques. Under the optimized conditions, 72.4% of protein was extracted from the microalgae Chlorella pyrenoidosa, which should contribute to the research and development of Chlorella protein in functional food and medicine. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Biogenic amine profile in unripe Arabica coffee beans processed according to dry and wet methods.

    PubMed

    Dias, Eduardo C; Pereira, Rosemary G F A; Borém, Flávio M; Mendes, Eulália; de Lima, Renato R; Fernandes, José O; Casal, Susana

    2012-04-25

    Immature coffee fruit processing contributes to a high amount of defective beans, which determines a significant amount of low-quality coffee sold in the Brazilian internal market. Unripe bean processing was tested, taking the levels of bioactive amines as criteria for evaluating the extent of fermentation and establishing the differences between processing methods. The beans were processed by the dry method after being mechanically depulped immediately after harvest or after a 12 h resting period in a dry pile or immersed in water. Seven bioactive amines were quantified: putrescine, spermine, spermidine, serotonin, cadaverine, histamine, and tyramine, with global amounts ranging from 71.8 to 80.3 mg/kg. The levels of spermine and spermidine were lower in the unripe depulped coffee than in the natural coffee. The specific conditions of dry and wet processing also influenced cadaverine levels, and histamine was reduced in unripe depulped coffee. A resting period of 12 h does not induce significant alteration on the beans and can be improved if performed in water. These results confirm that peeling immature coffee can decrease fermentation processes while providing more uniform drying, thus reducing the number of defects and potentially increasing beverage quality.

  11. Recent advancements in carbon nanofiber and carbon nanotube applications in drug delivery and tissue engineering.

    PubMed

    Stout, David A

    2015-01-01

    Since the discovery and synthesis of carbon nanotubes (CNTs) and carbon nanofibers (CNFs) over a decade ago, researchers have envisioned and discovered new potential applications for these materials. CNTs and CNFs have rapidly become a platform technology for a variety of uses, including biomedical applications due to their mechanical, electrical, thermal, optical and structural properties. CNTs and CNFs are also advantageous due to their ability to be produced in many different shapes and sizes. Since their discovery, of the many imaginable applications, CNTs and CNFs have gained a significant amount of attention and therapeutic potential in tissue engineering and drug delivery applications. In recent years, CNTs and CNFs have made significant contributions in designing new strategies for, delivery of pharmaceuticals, genes and molecular probes into cells, stem cell therapies and assisting in tissue regeneration. Furthermore, it is widely expressed that these materials will significantly contribute to the next generation of health care technologies in treating diseases and contributing to tissue growth. Hence, this review seeks to explore the recent advancements, current status and limitations of CNTs and CNFs for drug delivery and tissue engineering applications.

  12. Punishment as a means of competition: implications for strong reciprocity theory.

    PubMed

    Paál, Tünde; Bereczkei, Tamás

    2015-01-01

    Strong negative reciprocity, that is, sanctions imposed on norm violators at the punisher's own expense, has powerful cooperation-enhancing effects in both real-life and experimental game situations. However, it is plausible that punishment may obtain alternative roles depending on social context and the personality characteristics of participants. We examined the occurrence of punishing behavior among 80 subjects in a strongly competitive Public Goods game setting. Despite the punishment condition, the amount of the contributions decreased steadily during the game. The amount of contributions had no significant effect on received and imposed punishments. The results indicate that certain social contexts (in this case, intensive competition) exert modifying effects on the role that punishment takes on. Subjects punished each other in order to achieve a higher rank and a financially better outcome. Punishment primarily functioned as a means of rivalry, instead of as a way of second-order cooperation, as strong reciprocity suggests. These results indicate the need for the possible modification of the social conditions of punishment mechanisms described by the strong reciprocity theory as an evolutionary explanation of human cooperation.

  13. Punishment as a Means of Competition: Implications for Strong Reciprocity Theory

    PubMed Central

    Paál, Tünde; Bereczkei, Tamás

    2015-01-01

    Strong negative reciprocity, that is, sanctions imposed on norm violators at the punisher’s own expense, has powerful cooperation-enhancing effects in both real-life and experimental game situations. However, it is plausible that punishment may obtain alternative roles depending on social context and the personality characteristics of participants. We examined the occurrence of punishing behavior among 80 subjects in a strongly competitive Public Goods game setting. Despite the punishment condition, the amount of the contributions decreased steadily during the game. The amount of contributions had no significant effect on received and imposed punishments. The results indicate that certain social contexts (in this case, intensive competition) exert modifying effects on the role that punishment takes on. Subjects punished each other in order to achieve a higher rank and a financially better outcome. Punishment primarily functioned as a means of rivalry, instead of as a way of second-order cooperation, as strong reciprocity suggests. These results indicate the need for the possible modification of the social conditions of punishment mechanisms described by the strong reciprocity theory as an evolutionary explanation of human cooperation. PMID:25811464

  14. Effects of tongue cleaning on bacterial flora in tongue coating and dental plaque: a crossover study

    PubMed Central

    2014-01-01

    Background The effects of tongue cleaning on reconstruction of bacterial flora in dental plaque and tongue coating itself are obscure. We assessed changes in the amounts of total bacteria as well as Fusobacterium nucleatum in tongue coating and dental plaque specimens obtained with and without tongue cleaning. Methods We conducted a randomized examiner-blind crossover study using 30 volunteers (average 23.7 ± 3.2 years old) without periodontitis. After dividing randomly into 2 groups, 1 group was instructed to clean the tongue, while the other did not. On days 1 (baseline), 3, and 10, tongue coating and dental plaque samples were collected after recording tongue coating score (Winkel tongue coating index: WTCI). After a washout period of 3 weeks, the same examinations were performed with the subjects allocated to the alternate group. Genomic DNA was purified from the samples and applied to SYBR® Green-based real-time PCR to quantify the amounts of total bacteria and F. nucleatum. Results After 3 days, the WTCI score recovered to baseline, though the amount of total bacteria in tongue coating was significantly lower as compared to the baseline. In plaque samples, the bacterial amounts on day 3 and 10 were significantly lower than the baseline with and without tongue cleaning. Principal component analysis showed that variations of bacterial amounts in the tongue coating and dental plaque samples were independent from each other. Furthermore, we found a strong association between amounts of total bacteria and F. nucleatum in specimens both. Conclusions Tongue cleaning reduced the amount of bacteria in tongue coating. However, the cleaning had no obvious contribution to inhibit dental plaque formation. Furthermore, recovery of the total bacterial amount induced an increase in F. nucleatum in both tongue coating and dental plaque. Thus, it is recommended that tongue cleaning and tooth brushing should both be performed for promoting oral health. PMID:24423407

  15. Effects of tongue cleaning on bacterial flora in tongue coating and dental plaque: a crossover study.

    PubMed

    Matsui, Miki; Chosa, Naoyuki; Shimoyama, Yu; Minami, Kentaro; Kimura, Shigenobu; Kishi, Mitsuo

    2014-01-14

    The effects of tongue cleaning on reconstruction of bacterial flora in dental plaque and tongue coating itself are obscure. We assessed changes in the amounts of total bacteria as well as Fusobacterium nucleatum in tongue coating and dental plaque specimens obtained with and without tongue cleaning. We conducted a randomized examiner-blind crossover study using 30 volunteers (average 23.7 ± 3.2 years old) without periodontitis. After dividing randomly into 2 groups, 1 group was instructed to clean the tongue, while the other did not. On days 1 (baseline), 3, and 10, tongue coating and dental plaque samples were collected after recording tongue coating score (Winkel tongue coating index: WTCI). After a washout period of 3 weeks, the same examinations were performed with the subjects allocated to the alternate group. Genomic DNA was purified from the samples and applied to SYBR® Green-based real-time PCR to quantify the amounts of total bacteria and F. nucleatum. After 3 days, the WTCI score recovered to baseline, though the amount of total bacteria in tongue coating was significantly lower as compared to the baseline. In plaque samples, the bacterial amounts on day 3 and 10 were significantly lower than the baseline with and without tongue cleaning. Principal component analysis showed that variations of bacterial amounts in the tongue coating and dental plaque samples were independent from each other. Furthermore, we found a strong association between amounts of total bacteria and F. nucleatum in specimens both. Tongue cleaning reduced the amount of bacteria in tongue coating. However, the cleaning had no obvious contribution to inhibit dental plaque formation. Furthermore, recovery of the total bacterial amount induced an increase in F. nucleatum in both tongue coating and dental plaque. Thus, it is recommended that tongue cleaning and tooth brushing should both be performed for promoting oral health.

  16. Nutritional contribution of street foods to the diet of people in developing countries: a systematic review.

    PubMed

    Steyn, Nelia Patricia; McHiza, Zandile; Hill, Jillian; Davids, Yul Derek; Venter, Irma; Hinrichsen, Enid; Opperman, Maretha; Rumbelow, Julien; Jacobs, Peter

    2014-06-01

    To review studies examining the nutritional value of street foods and their contribution to the diet of consumers in developing countries. The electronic databases PubMed/MEDLINE, Web of Science, Cochrane Library, Proquest Health and Science Direct were searched for articles on street foods in developing countries that included findings on nutritional value. From a total of 639 articles, twenty-three studies were retained since they met the inclusion criteria. In summary, daily energy intake from street foods in adults ranged from 13 % to 50 % of energy and in children from 13 % to 40 % of energy. Although the amounts differed from place to place, even at the lowest values of the percentage of energy intake range, energy from street foods made a significant contribution to the diet. Furthermore, the majority of studies suggest that street foods contributed significantly to the daily intake of protein, often at 50 % of the RDA. The data on fat and carbohydrate intakes are of some concern because of the assumed high contribution of street foods to the total intakes of fat, trans-fat, salt and sugar in numerous studies and their possible role in the development of obesity and non-communicable diseases. Few studies have provided data on the intake of micronutrients, but these tended to be high for Fe and vitamin A while low for Ca and thiamin. Street foods make a significant contribution to energy and protein intakes of people in developing countries and their use should be encouraged if they are healthy traditional foods.

  17. [Contribution and challenges of Big Data in oncology].

    PubMed

    Saintigny, Pierre; Foy, Jean-Philippe; Ferrari, Anthony; Cassier, Philippe; Viari, Alain; Puisieux, Alain

    2017-03-01

    Since the first draft of the human genome sequence published in 2001, the cost of sequencing has dramatically decreased. The development of new technologies such as next generation sequencing led to a comprehensive characterization of a large number of tumors of various types as well as to significant advances in precision medicine. Despite the valuable information this technological revolution has allowed to produce, the vast amount of data generated resulted in the emergence of new challenges for the biomedical community, such as data storage, processing and mining. Here, we describe the contribution and challenges of Big Data in oncology. Copyright © 2016 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

  18. Contribution of mesopores in MgO-templated mesoporous carbons to capacitance in non-aqueous electrolytes

    NASA Astrophysics Data System (ADS)

    Kado, Yuya; Soneda, Yasushi; Yoshizawa, Noriko

    2015-02-01

    MgO-templated mesoporous carbons were fabricated by annealing trimagnesium dicitrate nonahydrate at various temperatures from 700 to 1000 °C with subsequent acid leaching of MgO. The obtained carbons contained a large amount of mesopores. Performances of electric double-layer capacitors using these carbons were examined for propylene carbonate electrolyte containing 1 M tetraethylammonium tetrafluoroborate. The mesoporous carbons synthesized at higher temperatures showed better rate capabilities. AC impedance measurements indicated that high-temperature annealing of the carbon precursors and the presence of mesopores were important for high rate performance. In addition, the contribution of mesopores to capacitance was more significant at higher current densities of 30 A g-1.

  19. Genetic contributions to antisocial personality and behavior: a meta-analytic review from an evolutionary perspective.

    PubMed

    Ferguson, Christopher J

    2010-01-01

    Evidence from behavioral genetics supports the conclusion that a significant amount of the variance in antisocial personality and behavior (APB) is due to genetic contributions. Many scientific fields such as psychology, medicine, and criminal justice struggle to incorporate this information with preexisting paradigms that focused exclusively on external or learned etiology of antisocial behavior. The current paper presents a meta-analytic review of behavioral genetic etiological studies of APB. Results indicated that 56% of the variance in APB can be explained through genetic influences, with 11% due to shared non-genetic influences, and 31% due to unique non-genetic influences. This data is discussed in relation to evolutionary psychological theory.

  20. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... function constituting the ground for the exemption of the organization to which the contribution is made...)(3). In general, the amount of the reduction is equal to one-half of the amount of gain (other than gain described in paragraph (d) of this section) which would not have been long-term capital gain if...

  1. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... function constituting the ground for the exemption of the organization to which the contribution is made...)(3). In general, the amount of the reduction is equal to one-half of the amount of gain (other than gain described in paragraph (d) of this section) which would not have been long-term capital gain if...

  2. 26 CFR 1.170A-4 - Reduction in amount of charitable contributions of certain appreciated property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... this section, by the amount of gain (hereinafter in this section referred to as ordinary income) which would have been recognized as gain which is not long-term capital gain if the property had been sold by...) In the case of a contribution by an individual of section 170(e) capital gain property, as defined in...

  3. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... function constituting the ground for the exemption of the organization to which the contribution is made...)(3). In general, the amount of the reduction is equal to one-half of the amount of gain (other than gain described in paragraph (d) of this section) which would not have been long-term capital gain if...

  4. The effects of physical activity on impulsive choice: Influence of sensitivity to reinforcement amount and delay.

    PubMed

    Strickland, Justin C; Feinstein, Max A; Lacy, Ryan T; Smith, Mark A

    2016-05-01

    Impulsive choice is a diagnostic feature and/or complicating factor for several psychological disorders and may be examined in the laboratory using delay-discounting procedures. Recent investigators have proposed using quantitative measures of analysis to examine the behavioral processes contributing to impulsive choice. The purpose of this study was to examine the effects of physical activity (i.e., wheel running) on impulsive choice in a single-response, discrete-trial procedure using two quantitative methods of analysis. To this end, rats were assigned to physical activity or sedentary groups and trained to respond in a delay-discounting procedure. In this procedure, one lever always produced one food pellet immediately, whereas a second lever produced three food pellets after a 0, 10, 20, 40, or 80-s delay. Estimates of sensitivity to reinforcement amount and sensitivity to reinforcement delay were determined using (1) a simple linear analysis and (2) an analysis of logarithmically transformed response ratios. Both analyses revealed that physical activity decreased sensitivity to reinforcement amount and sensitivity to reinforcement delay. These findings indicate that (1) physical activity has significant but functionally opposing effects on the behavioral processes that contribute to impulsive choice and (2) both quantitative methods of analysis are appropriate for use in single-response, discrete-trial procedures. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. How much is enough? An analysis of CD measurement amount for mask characterization

    NASA Astrophysics Data System (ADS)

    Ullrich, Albrecht; Richter, Jan

    2009-10-01

    The demands on CD (critical dimension) metrology amount in terms of both reproducibility and measurement uncertainty steadily increase from node to node. Different mask characterization requirements have to be addressed like very small features, unevenly distributed features, contacts, semi-dense structures to name only a few. Usually this enhanced need is met by an increasing number of CD measurements, where the new CD requirements are added to the well established CD characterization recipe. This leads straight forwardly to prolonged cycle times and highly complex evaluation routines. At the same time mask processes are continuously improved to become more stable. The enhanced stability offers potential to actually reduce the number of measurements. Thus, in this work we will start to address the fundamental question of how many CD measurements are needed for mask characterization for a given confidence level. We used analysis of variances (ANOVA) to distinguish various contributors like mask making process, measurement tool stability and measurement methodology. These contributions have been investigated for classical photomask CD specifications e.g. mean to target, CD uniformity, target offset tolerance and x-y bias. We found depending on specification that the importance of the contributors interchanges. Interestingly, not only short and long-term metrology contributions are dominant. Also the number of measurements and their spatial distribution on the mask layout (sampling methodology) can be the most important part of the variance. The knowledge of contributions can be used to optimize the sampling plan. As a major finding, we conclude that there is potential to reduce a significant amount of measurements without loosing confidence at all. Here, full sampling in x and y as well as full sampling for different features can be shortened substantially almost up to 50%.

  6. Health properties of oca (Oxalis tuberosa) and yacon (Smallanthus sonchifolius).

    PubMed

    Jimenez, María Eugenia; Rossi, Analia; Sammán, Norma

    2015-10-01

    Andean roots and tubers are underexploited crops; many contain compounds beneficial to health, so a greater knowledge of their properties is important for encouraging their consumption. The aim of this work was to study the content of bioactive compounds of yacon and oca and their effect on intestinal health using as a model rats of the Wistar strain. Two varieties of ocas (Overa and Rosada) and yacon, which contain significant amounts of fructooligosaccharides and phenolic compounds, were chosen. Rats of the Wistar strain were fed for two months with diets containing these foods in amounts sufficient to provide 8% of fiber. A significant decrease in pH values and an increment in lactobacilli and bifidobacteria counts in the cecum of rats fed with inulin, oca Rosada and Overa were observed; there was no significant decrease in enterobacteriaceae and enterococci counts. The cecum antioxidant activity was incremented in rats fed with the experimental foods with respect to the control diets. The components of dietary fiber and phenolic compound contents in yacon and oca produce effects that contribute to the intestinal health of the experimental animals.

  7. Natural Flood Management Plus: Scaling Up Nature Based Solutions to Larger Catchments

    NASA Astrophysics Data System (ADS)

    Quinn, Paul; Nicholson, Alex; Adams, Russ

    2017-04-01

    It has been established that networks NFM features, such as ponds and wetlands, can have a significant effect on flood flow and pollution at local scales (less than 10km2). However, it is much less certain that NFM and NBS can impact at larger scales and protect larger cities. This is especially true for recent storms in the UK such as storm Desmond that caused devastation across the north of England. It is possible using observed rainfall and runoff data to estimate the amounts of storage that would be required to impact on extreme flood events. Here we will how a toolkit that will estimate the amount of storage that can be accrued through a dense networks of NFM features. The analysis suggest that the use of many hundreds of small NFM features can have a significant impact on peak flow, however we still require more storage in order to address extreme events and to satisfy flood engineers who may propose more traditional flood defences. We will also show case studies of larger NFM feature positioned on flood plains that can store significantly more flood flow. Examples designs of NFM plus feature will be shown. The storage aggregation tool will then show the degree to which storing large amounts of flood flow in NFM plus features can contribute to flood management and estimate the likely costs. Together smaller and larger NFM features if used together can produce significant flood storage and at a much lower cost than traditional schemes.

  8. Mechanisms of volatile production from non-sulfur amino acids by irradiation

    NASA Astrophysics Data System (ADS)

    Ahn, Dong Uk; Lee, Eun Joo; Feng, Xi; Zhang, Wangang; Lee, Ji Hwan; Jo, Cheorun; Nam, Kichang

    2016-02-01

    Non-sulfur amino acid monomers were used to study the mechanisms of volatile production in meat by irradiation. Irradiation not only produced many volatiles but also increased the amounts of volatiles from non-sulfur amino acid monomers. The major reaction mechanisms involved in volatile production from each group of the amino acids by irradiation differ significantly. However, we speculate that the radiolysis of amino acid side chains were the major mechanism. In addition, Strecker degradation, especially the production of aldehydes from aliphatic group amino acids, and deamination, isomerization, decarboxylation, cyclic reaction and dehydrogenation of the initial radiolytic products were also contributed to the production of volatile compounds. Each amino acid monomers produced different odor characteristics, but the intensities of odor from all non-sulfur amino acid groups were very weak. This indicated that the contribution of volatiles produced from non-sulfur amino acids was minor. If the volatile compounds from non-sulfur amino acids, especially aldehydes, interact with other volatiles compounds such as sulfur compounds, however, they can contribute to the off-odor of irradiated meat significantly.

  9. Non-Caking Freeze Dried Applesauce

    DTIC Science & Technology

    A study was initiated to develop an applesauce which resists caking when subjected to elevated temperatures such as 37.7C. for two weeks and/or 57C...following results were obtained: (1) The degree of caking of the freeze dried applesauce powder was correlated with the amount of juice extracted. (2... applesauce powders. (3) Reducing sugars appear to be the factor contributing most significantly to the caking with the higher reducing sugar levels producing the higher degrees of caking.

  10. Quantitative Analysis of the Contributing Factors Affecting Specialty Care No-Show Rates at Brooke Army Medical Center

    DTIC Science & Technology

    2007-03-30

    2002). In the Vein Treatment Surgery Center in Texas, failure to properly cancel cosmetic appointments will result in forfeiture of the patients’ $100...appointments. This problem affects more than just the United States. Missed appointments cost the National Healthcare System ( NHS ) in England a...significant amount of money last year. Official figures from the NHS showed 5.7 million appointments were missed in 2004-2005 (Carvel, 2006). When patients

  11. Analysis of the UV-B Regime and Potential Effects on Alfalfa

    NASA Technical Reports Server (NTRS)

    Seitz, Jeffery C.

    1998-01-01

    Life at the surface of the Earth, over the last 400 m.y., evolved under conditions of decreased short-wave radiation (i.e., ultraviolet) relative to solar output due to absorption and scattering by constituents (e.g., ozone, water vapor, aerosols) in the upper atmosphere. However, a significant amount of ultraviolet radiation in the range from 280-320 nm, known as ultraviolet-B radiation, reaches the Earth's surface and has sufficient energy to be damaging to biologic tissue. Natural fluctuations in atmospheric constituents (seasonal variation, volcanic eruptions, etc.), changes in the orbital attitude of the Earth (precession, axial tilt, orbital eccentricity), and long-term solar variability contribute to changes in the total amount of ultraviolet radiation reaching the surface of the Earth, and thus, the biosphere. More recently, the atmospheric release of commercial propellants and refrigerants, known as chlorofluorocarbons (CFCs), has contributed to a significant depletion in naturally occurring ozone in the stratosphere. Thus, decreased stratospheric ozone has resulted in an increased UV-B flux at the Earth's surface which may have profound effects on terrestrial and marine organisms. In this study, we are investigating the effects of differing solar UV-B fluxes on alfalfa (Medicago sativa L.), an important agricultural crop. A long-term goal of this research is to develop spectral signatures to detect plant response to increased UV-B radiation from remote sensor platforms.

  12. Evaluation of patient satisfaction with physical therapy following primary THA.

    PubMed

    Issa, Kimona; Naziri, Qais; Johnson, Aaron J; Memon, Talha; Dattilo, Jonathan; Harwin, Steven F; Mont, Michael A

    2013-05-01

    Physical therapy following total hip arthroplasty (THA) is intended to maximize a patient's range of motion and function and improve the quality of life. No universally accepted standard of care exists for physical therapy among physicians or therapists. However, it may be crucial to enhance efforts to more fully elucidate contributing parameters that affect patient experiences. The purpose of this study was to evaluate various factors contributing to patient satisfaction with postoperative physical therapy. One hundred consecutive patients (110 hips) who underwent THA were prospectively surveyed for satisfaction with postoperative physical therapy. All surveys were filled out anonymously by the patients, and investigators were blinded to clinical outcomes and who was surveyed. Seventy-six percent of patients reported being satisfied with their rehabilitation experiences. Factors, including patient age and sex, duration of therapy, number of patients per session, continuity of care with the same therapist, amount of hands-on time spent with the therapist, number of patients per session, and total number of sessions completed, were significantly correlated with patient satisfaction. Co-pay amount did not significantly affect patient satisfaction. These factors may be underappreciated by physicians and physical therapists. To maximize patient satisfaction with physical therapy, physicians should identify institutions whose therapists are willing to spend adequate hands-on time during one-on-one or small-group sessions while maintaining the greatest possible continuity of care with a single provider. Copyright 2013, SLACK Incorporated.

  13. ICT reuse in socio-economic enterprises.

    PubMed

    Ongondo, F O; Williams, I D; Dietrich, J; Carroll, C

    2013-12-01

    In Europe, socio-economic enterprises such as charities, voluntary organisations and not-for-profit companies are involved in the repair, refurbishment and reuse of various products. This paper characterises and analyses the operations of socio-economic enterprises that are involved in the reuse of Information and Communication Technology (ICT) equipment. Using findings from a survey, the paper specifically analyses the reuse activities of socio-economic enterprises in the U.K. from which Europe-wide conclusions are drawn. The amount of ICT products handled by the reuse organisations is quantified and potential barriers and opportunities to their operations are analysed. By-products from reuse activities are discussed and recommendations to improve reuse activities are provided. The most common ICT products dealt with by socio-economic enterprises are computers and related equipment. In the U.K. in 2010, an estimated 143,750 appliances were reused. However, due to limitations in data, it is difficult to compare this number to the amount of new appliances that entered the U.K. market or the amount of waste electrical and electronic equipment generated in the same period. Difficulties in marketing products and numerous legislative requirements are the most common barriers to reuse operations. Despite various constraints, it is clear that organisations involved in reuse of ICT could contribute significantly to resource efficiency and a circular economy. It is suggested that clustering of their operations into "reuse parks" would enhance both their profile and their products. Reuse parks would also improve consumer confidence in and subsequently sales of the products. Further, it is advocated that industrial networking opportunities for the exchange of by-products resulting from the organisations' activities should be investigated. The findings make two significant contributions to the current literature. One, they provide a detailed insight into the reuse operations of socio-economic enterprises. Previously unavailable data has been presented and analysed. Secondly, new evidence about the by-products/materials resulting from socio-economic enterprises' reuse activities has been obtained. These contributions add substantially to our understanding of the important role of reuse organisations. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Atmospheric PM and volatile organic compounds released from Mediterranean shrubland wildfires

    NASA Astrophysics Data System (ADS)

    Garcia-Hurtado, Elisa; Pey, Jorge; Borrás, Esther; Sánchez, Pilar; Vera, Teresa; Carratalá, Adoración; Alastuey, Andrés; Querol, Xavier; Vallejo, V. Ramon

    2014-06-01

    Wildfires produce a significant release of gases and particles affecting climate and air quality. In the Mediterranean region, shrublands significantly contribute to burned areas and may show specific emission profiles. Our objective was to depict and quantify the primary-derived aerosols and precursors of secondary particulate species released during shrubland experimental fires, in which fire-line intensity values were equivalent to those of moderate shrubland wildfires, by using a number of different methodologies for the characterization of organic and inorganic compounds in both gas-phase and particulate-phase. Emissions of PM mass, particle number concentrations and organic and inorganic PMx components during flaming and smouldering phases were characterized in a field shrubland fire experiment. Our results revealed a clear prevalence of K+ and SO42- as inorganic ions released during the flaming-smouldering processes, accounting for 68-80% of the inorganic soluble fraction. During the residual-smouldering phases, in addition to K+ and SO42-, Ca2+ was found in significant amounts probably due the predominance of re-suspension processes (ashes and soil dust) over other emission sources during this stage. Concerning organic markers, the chromatograms were dominated by phenols, n-alkanals and n-alkanones, as well as by alcohol biomarkers in all the PMx fractions investigated. Levoglucosan was the most abundant degradation compound with maximum emission factors between 182 and 261 mg kg-1 in PM2.5 and PM10 respectively. However, levoglucosan was also observed in significant amounts in the gas-phase. The most representative organic volatile constituents in the smoke samples were alcohols, carbonyls, acids, monocyclic and bicyclic arenes, isoprenoids and alkanes compounds. The emission factors obtained in this study may contribute to the validation and improvement of national and international emission inventories of this intricate and diffuse emission source.

  15. Cellulase stability, adsorption/desorption profiles and recycling during successive cycles of hydrolysis and fermentation of wheat straw.

    PubMed

    Rodrigues, Ana Cristina; Felby, Claus; Gama, Miguel

    2014-03-01

    The potential of enzymes recycling after hydrolysis and fermentation of wheat straw under a variety of conditions was investigated, monitoring the activity of the enzymes in the solid and liquid fractions, using low molecular weight substrates. A significant amount of active enzymes could be recovered by recycling the liquid phase. In the early stage of the process, enzyme adsorb to the substrate, then gradually returning to the solution as the saccharification proceeds. At 50°C, normally regarded as an acceptable operational temperature for saccharification, the enzymes (Celluclast) significantly undergo thermal deactivation. The hydrolysis yield and enzyme recycling efficiency in consecutive recycling rounds can be increased by using high enzyme loadings and moderate temperatures. Indeed, the amount of enzymes in the liquid phase increased with its thermostability and hydrolytic efficiency. This study contributes towards developing effective enzymes recycling strategies and helping to reduce the enzyme costs on bioethanol production. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Determination of the D and L isomers of some protein amino acids present in soils

    NASA Technical Reports Server (NTRS)

    Pollock, G. E.; Cheng, C.-N.; Cronin, S. E.

    1977-01-01

    The D and L isomers of some protein amino acids present in soils were measured by using a gas chromatographic technique. The results of two processing procedures were compared to determine the better method. Results of the comparison indicated that the determination of D and L percentages requires amino acid purification if one is to obtain accurate data. It was found that very significant amounts of D-alanine, D-aspartic acid, and D-glutamic acid were present in the contemporary soils studied. Valine, isoleucine, leucine, proline, and phenylalanine generally contained only a trace to very small amounts of the D isomer. It is probable that the D-amino acids from the alanine, aspartic, and glutamic acids are contributed to the soil primarily via microorganisms. The finding of very significant quantities of some D-amino acids (about 5-16%) in present-day soils may alert some investigators of geological sediments to a possible problem in using amino acid racemization as an age-dating technique.

  17. THE INFLUENCE OF SOCIAL SUPPORT ON PSYCHOLOGICAL DISTRESS IN OLDER PERSONS: AN EXAMINATION OF INTERACTION PROCESSES IN AUSTRALIA.

    PubMed

    Sharpley, Christopher; Hussain, Rafat; Wark, Stuart; Mcevoy, Mark; Attia, John

    2015-12-01

    Social support is proposed as a coping mechanism against anxiety and depression amongst older persons, but few data have examined how this occurs. This study assessed the contributions of two sub-components of social support as mediators against psychological distress-broadly defined as anxiety and depression. 1,560 men and 1,758 women from the Hunter Community Study (Australia) completed the Duke Social Support Scale and the Kessler Psychological Distress Scale. The Duke Social Support Scale examined the amount of social interaction and satisfaction with social interactions. Significant mediating effects of social support were found in the Kessler Psychological Distress Scale items measuring depression but not anxiety. Satisfaction with social support was a significant predictor of Kessler Psychological Distress Scale total score and Sadness items, but the amount of social support was not a predictor of stress. Social support may assist with symptoms of depression, i.e., specific sadness/depressed mood, but not necessarily with anxiety. Implications for policy and service delivery were discussed.

  18. Accelerating forest growth enhancement due to climate and atmospheric changes in British Colombia, Canada over 1956-2001.

    PubMed

    Wu, Chaoyang; Hember, Robbie A; Chen, Jing M; Kurz, Werner A; Price, David T; Boisvenue, Céline; Gonsamo, Alemu; Ju, Weimin

    2014-03-25

    Changes in climate and atmospheric CO2 and nitrogen (N) over the last several decades have induced significant effects on forest carbon (C) cycling. However, contributions of individual factors are largely unknown because of the lack of long observational data and the undifferentiating between intrinsic factors and external forces in current ecosystem models. Using over four decades (1956-2001) of forest inventory data at 3432 permanent samples in maritime and boreal regions of British Columbia (B.C.), Canada, growth enhancements were reconstructed and partitioned into contributions of climate, CO2 and N after removal of age effects. We found that climate change contributed a particularly large amount (over 70%) of the accumulated growth enhancement, while the remaining was attributed to CO2 and N, respectively. We suggest that climate warming is contributing a widespread growth enhancement in B.C.'s forests, but ecosystem models should consider CO2 and N fertilization effects to fully explain inventory-based observations.

  19. Evaluation of the volatile profile of Tuber liyuanum by HS-SPME with GC-MS.

    PubMed

    Liu, Changjiao; Li, Yu

    2017-04-01

    The volatile components of Tuber liyuanum were determined by HS-SPME with GC-MS for the first time. The effects of different fibre coating, extraction time, extraction temperature and sample amount were studied to get optimal extraction conditions. The optimal conditions were SPME fibre of Carboxen/PDMS, extraction time of 40 min, extraction temperature of 80 °C, sample amount of 2 g. Under these conditions 57 compounds in volatile of T. liyuanum were detected with a resemblance percentage above 80%. Aldehydes and aromatics were the main chemical families identified. The contribution of 3-Octanone(11.67%), phenylethyl alcohol (10.60%), isopentana (9.29%) and methylbutana (8.06%) for the total volatile profile were more significant in T. liyuanum than other compounds.

  20. Germinated and Ungerminated Seeds Extract from Two Lupinus Species: Biological Compounds Characterization and In Vitro and In Vivo Evaluations

    PubMed Central

    Andor, Bogdan; Alexa, Ersilia; Hogea, Elena; Coricovac, Dorina; Pătrașcu, Jenel Marian; Mioc, Marius; Cristina, Romeo Teodor; Soica, Codruta; Dehelean, Cristina

    2016-01-01

    In recent years, nutraceuticals attracted a great amount of attention in the biomedical research due to their significant contribution as natural agents for prevention of various health issues. Ethanolic extracts from the ungerminated and germinated seeds of Lupinus albus L. and Lupinus angustifolius L. were analyzed for the content in isoflavones (genistein) and cinnamic acid derivatives. Additionally, the extracts were evaluated for antimicrobial, antiproliferative, and anti-inflammatory properties, using in vitro and in vivo tests. Germination proved to be a method of choice in increasing the amount of genistein and cinnamic acid derivatives in both Lupinus albus L. and Lupinus angustifolius L. seeds. Biological evaluation of all vegetal extracts revealed a weak therapeutic potential for both ungerminated and germinated seeds. PMID:28090213

  1. Addressing Water Consumption of Evaporative Coolers with Greywater

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sahai, Rashmi; Shah, Nihar; Phadke, Amol

    Evaporative coolers (ECs) provide significant gains in energy efficiency compared to vapor compression air conditioners, but simultaneously have significant onsite water demand. This can be a major barrier to deployment in areas of the world with hot and arid climates. To address this concern, this study determined where in the world evaporative cooling is suitable, the water consumption of ECs in these cities, and the potential that greywater can be used reduce the consumption of potable water in ECs. ECs covered 69percent of the cities where room air conditioners are may be deployed, based on comfort conditions alone. The averagemore » water consumption due to ECs was found to be 400 L/household/day in the United States and Australia, with the potential for greywater to provide 50percent this amount. In the rest of the world, the average water consumption was 250 L/household/day, with the potential for greywater to supply 80percent of this amount. Home size was the main factor that contributed to this difference. In the Mediterranean, the Middle East, Northern India, and the Midwestern and Southwestern United States alkalinity levels are high and water used for bleeding will likely contribute significantly to EC water consumption. Although technically feasible, upfront costs for household GW systems are currently high. In both developed and developing parts of the world, however, a direct EC and GW system is cost competitive with conventional vapor compression air conditioners. Moreover, in regions of the world that face problems of water scarcity the benefits can substantially outweigh the costs.« less

  2. 26 CFR 1.5000A-0 - Table of contents.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) Required contribution percentage. (i) In general. (ii) Indexing. (iii) Plan year. (3) Individuals eligible...) Applicable dollar amount. (iii) Special applicable dollar amount for individuals under age 18. (iv) Indexing...

  3. Energy Inputs Uncertainty: Total Amount, Distribution and Correlation Between Different Forms of Energy

    NASA Technical Reports Server (NTRS)

    Deng, Yue

    2014-01-01

    Describes solar energy inputs contributing to ionospheric and thermospheric weather processes, including total energy amounts, distributions and the correlation between particle precipitation and Poynting flux.

  4. 7 CFR 1484.73 - Are Cooperators penalized for failing to make required contributions?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Are Cooperators penalized for failing to make... Cooperators penalized for failing to make required contributions? A Cooperator's contribution requirement is specified in the Cooperator program allocation letter. If a Cooperator fails to contribute the amount...

  5. 7 CFR 1484.73 - Are Cooperators penalized for failing to make required contributions?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Are Cooperators penalized for failing to make... Cooperators penalized for failing to make required contributions? A Cooperator's contribution requirement is specified in the Cooperator program allocation letter. If a Cooperator fails to contribute the amount...

  6. 7 CFR 1484.73 - Are Cooperators penalized for failing to make required contributions?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Are Cooperators penalized for failing to make... Cooperators penalized for failing to make required contributions? A Cooperator's contribution requirement is specified in the Cooperator program allocation letter. If a Cooperator fails to contribute the amount...

  7. 21 CFR 331.20 - Determination of percent contribution of active ingredients.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Determination of percent contribution of active... Procedures § 331.20 Determination of percent contribution of active ingredients. To determine the percent contribution of an antacid active ingredient, place an accurately weighed amount of the antacid active...

  8. 21 CFR 331.20 - Determination of percent contribution of active ingredients.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Determination of percent contribution of active... Procedures § 331.20 Determination of percent contribution of active ingredients. To determine the percent contribution of an antacid active ingredient, place an accurately weighed amount of the antacid active...

  9. 21 CFR 331.20 - Determination of percent contribution of active ingredients.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Determination of percent contribution of active... Procedures § 331.20 Determination of percent contribution of active ingredients. To determine the percent contribution of an antacid active ingredient, place an accurately weighed amount of the antacid active...

  10. 21 CFR 331.20 - Determination of percent contribution of active ingredients.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Determination of percent contribution of active... Procedures § 331.20 Determination of percent contribution of active ingredients. To determine the percent contribution of an antacid active ingredient, place an accurately weighed amount of the antacid active...

  11. Current and emerging concepts in muscle tension dysphonia: a 30-month review.

    PubMed

    Altman, Kenneth W; Atkinson, Cory; Lazarus, Cathy

    2005-06-01

    The modern theory of hoarseness is that there are multifactorial etiologies contributing to the voice problem. The hypothesis of this study is that muscle tension dysphonia is multifactorial with various contributing etiologies. This project is a retrospective chart review of all patients seen in the Voice Speech and Language Service and Swallowing Center at our institution with a diagnosis of muscle tension (functional hypertensive) dysphonia over a 30-month period. A literature search and review is also performed regarding current and emerging concepts of muscle tension dysphonia. One hundred fifty subjects were identified (60% female, 40% male, with a mean age of 42.3 years). Significant factors in patient history believed to contribute to abnormal voice production were gastroesophageal reflux in 49%, high stress levels in 18%, excessive amounts of voice use in 63%, and excessive loudness demands on voice use in 23%. Otolaryngologic evaluation was performed in 82% of patients, in whom lesions, significant vocal fold edema, or paralysis/paresis was identified in 52.3%. Speech pathology assessment revealed poor breath support, inappropriately low pitch, and visible cervical neck tension in the majority of patients. Inappropriate intensity was observed in 23.3% of patients. This set of multiple contributing factors is discussed in the context of current and emerging understanding of muscle tension dysphonia. Results confirm multifactorial etiologies contributing to hoarseness in the patients identified with muscle tension dysphonia. An interdisciplinary approach to treating all contributing factors portends the best prognosis.

  12. Radiation Dose from Reentrant Electrons

    NASA Technical Reports Server (NTRS)

    Badhwar, G.D.; Cleghorn, T. E.; Watts, J.

    2003-01-01

    In estimating the crew exposures during an EVA, the contribution of reentrant electrons has always been neglected. Although the flux of these electrons is small compared to the flux of trapped electrons, their energy spectrum extends to several GeV compared to about 7 MeV for trapped electrons. This is also true of splash electrons. Using the measured reentrant electron energy spectra, it is shown that the dose contribution of these electrons to the blood forming organs (BFO) is more than 10 times greater than that from the trapped electrons. The calculations also show that the dose-depth response is a very slowly changing function of depth, and thus adding reasonable amounts of additional shielding would not significantly lower the dose to BFO.

  13. Insights into Brown Adipose Tissue Physiology as Revealed by Imaging Studies

    PubMed Central

    Izzi-Engbeaya, Chioma; Salem, Victoria; Atkar, Rajveer S; Dhillo, Waljit S

    2014-01-01

    There has been resurgence in interest in brown adipose tissue (BAT) following radiological and histological identification of metabolically active BAT in adult humans. Imaging enables BAT to be studied non-invasively and therefore imaging studies have contributed a significant amount to what is known about BAT function in humans. In this review the current knowledge (derived from imaging studies) about the prevalence, function, activity and regulation of BAT in humans (as well as relevant rodent studies), will be summarized. PMID:26167397

  14. A prospective study of differential sources of school-related social support and adolescent global life satisfaction.

    PubMed

    Siddall, James; Huebner, E Scott; Jiang, Xu

    2013-01-01

    This study examined the cross-sectional and prospective relationships between three sources of school-related social support (parent involvement, peer support for learning, and teacher-student relationships) and early adolescents' global life satisfaction. The participants were 597 middle school students from 1 large school in the southeastern United States who completed measures of school social climate and life satisfaction on 2 occasions, 5 months apart. The results revealed that school-related experiences in terms of social support for learning contributed substantial amounts of variance to individual differences in adolescents' satisfaction with their lives as a whole. Cross-sectional multiple regression analyses of the differential contributions of the sources of support demonstrated that family and peer support for learning contributed statistically significant, unique variance to global life satisfaction reports. Prospective multiple regression analyses demonstrated that only family support for learning continued to contribute statistically significant, unique variance to the global life satisfaction reports at Time 2. The results suggest that school-related experiences, especially family-school interactions, spill over into adolescents' overall evaluations of their lives at a time when direct parental involvement in schooling and adolescents' global life satisfaction are generally declining. Recommendations for future research and educational policies and practices are discussed. © 2013 American Orthopsychiatric Association.

  15. Sources of heterogeneity in studies of the BMI-mortality association.

    PubMed

    Peter, Raphael Simon; Nagel, Gabriele

    2017-06-01

    To date, the amount of heterogeneity among studies of the body mass index-mortality association attributable to differences in the age distribution and length of follow-up has not been quantified. Therefore, we wanted to quantify the amount of heterogeneity attributable to age and follow-up in results of studies on the body mass index-mortality relation. We used optima of the body mass index mortality association reported for 30 populations and performed meta-regression to estimate the amount of heterogeneity attributable to sex, ethnicity, mean age at baseline, percentage smokers, and length of follow-up. Ethnicity as single factor accounted for 36% (95% CI, 11-56%) of heterogeneity. Mean age and length of follow-up had an interactive effect and together accounted for 56% (95% CI, 24-74%) of the remaining heterogeneity. Sex did not significantly contribute to the heterogeneity, after controlling for ethnicity, age, and length of follow-up. A considerable amount of heterogeneity in studies of the body mass index-mortality association is attributable to ethnicity, age, and length of follow-up. Copyright © 2017 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

  16. The relative contribution of profile body shape and weight to judgements of women's physical attractiveness in Britain and Malaysia.

    PubMed

    Swami, Viren; Tovée, Martin J

    2007-12-01

    Ninety-six Malaysian and British men rated for physical attractiveness a set of photographs of real women in profile, with known body mass index (BMI) and waist-to-hip ratio (WHR). Results showed that BMI accounted for the greater amount of variance in all settings. There were also significant differences in preferences for body weight, with low resource, low socioeconomic status (SES) raters preferring a significantly heavier partner than high resource, high SES raters. The disparity with previous findings using line drawings of women in profile was discussed in terms of the weaknesses of line-drawn stimuli.

  17. Kinetics of Rituximab Excretion into Urine and Peritoneal Fluid in Two Patients with Nephrotic Syndrome.

    PubMed

    Stahl, Klaus; Duong, Michelle; Schwarz, Anke; Wagner, A D; Haller, Hermann; Schiffer, Mario; Jacobs, Roland

    2017-01-01

    Clinical observations suggest that treatment of Rituximab might be less effective in patients with nephrotic range proteinuria when compared to nonnephrotic patients. It is conceivable that the reason for this is that significant amounts of Rituximab might be lost in the urine in a nephrotic patient and that these patients require a repeated or higher dosage. However, this has not been systematically studied. In this case report we describe two different patients with nephrotic range proteinuria receiving Rituximab. The first patient received Rituximab for therapy resistant cryoglobulinemic membranoproliferative glomerulonephritis and the other for second line treatment of Felty's syndrome. We employed flow cytometry to determine the amount of Rituximab excretion in both urine and peritoneal fluid specimens in these patients following administration of Rituximab. We found that a significant amount of Rituximab is lost from the circulation by excretion into the urine. Furthermore we saw a close correlation of the excretion of Rituximab to the excretion of IgG molecules suggesting selectivity of proteinuria as the determining factor of Rituximab excretion. Further larger scale clinical studies could have the potential to evaluate an optimal cut-off value of IgG urinary loss before a possible administration of Rituximab therefore contributing to a more individualized treatment approach in patients with nonselective and nephrotic range proteinuria.

  18. Calcitonin gene-related peptide and somatostatin releases correlated with the area under the lafutidine concentration-time curve in human plasma.

    PubMed

    Ikawa, K; Shimatani, T; Azuma, Y; Inoue, M; Morikawa, N

    2006-08-01

    To examine the effects of the histamine H(2)-receptor antagonist, lafutidine, at clinical dosage (10 mg tablet after a standardized meal) on plasma levels of the gastrointestinal peptides, calcitonin gene-related peptide (CGRP), somatostatin and gastrin. Six healthy male volunteers ate a standardized meal, and received either lafutidine orally at a dose of 10 mg or water only (control). Blood samples were taken before and up to 4 h after the drug administration. Plasma lafutidine concentrations were determined by high pressure liquid chromatography. Pharmacokinetic analysis of lafutidine was performed using one-compartmental model. The levels of immunoreactive substances of plasma CGRP, somatostatin and gastrin were measured by enzyme immunoassay, and the amount of peptide release was calculated by the trapezoidal method. Lafutidine significantly increased plasma CGRP levels at 1, 1.5, 2.5 and 4 h and the total amount of CGRP release (192 +/- 14.0 pg.h/mL) compared with the control group (128 +/- 21.5 pg.h/mL). Lafutidine significantly increased the plasma somatostatin levels at 1 and 1.5 h, and the total amount of somatostatin released (107 +/- 18.2 pg.h/mL) compared with the control (78.4 +/- 7.70 pg.h/mL). The area under the drug concentration-time curve (AUC) from 0 to 4 h after administration correlated well with the Delta-CGRP and Delta-somatostatin release but not with total amount of gastrin released. However, plasma gastrin levels were significantly elevated at 1.5 h after drug administration. Lafutidine at clinical dosage increases plasma CGRP and the somatostatin. The amounts released correlated with the AUC of lafutidine in humans. These results suggest that the increased release of CGRP and somatostatin may contribute to its gastroprotective and anti-acid secretory effect.

  19. Effect of Body Mass Index on Postoperative Transfusions and 24-Hour Chest-Tube Output

    PubMed Central

    Nolan, Heather R.; Ramaiah, Chandrashekhar

    2011-01-01

    An increasing obese population in the United States focuses attention on the effect of obesity on surgical outcomes. Our objective was to see if obesity, determined by body mass index (BMI), contributed to bleeding in coronary artery bypass graft (CABG) surgery as measured by intraoperative and postoperative packed red blood cell transfusion frequency and amount and 24-hour chest-tube output. A retrospective chart review examined 150 subjects undergoing single-surgeon off-pump or on-pump CABG surgery between September 2006 and April 2009. BMI groups included normal-weight (BMI <25), overweight (BMI 25 to 29), and obese (BMI ≥30). Analyses used a chi-square test to determine variances in number of transfusions, and ANOVA for transfusion amount and 24-hour chest-tube amount. The percentage of subjects receiving intraoperative transfusions varied significantly by BMI group (p = 0.022). The percentage of subjects receiving transfusions in the 72-hour postoperative period showed a decreasing linear trend based on BMI group (p = 0.054). The percentage of subjects receiving transfusions in the combined intraoperative or 72-hour postoperative period showed a decreasing linear trend based on BMI group (p = 0.054). The transfusion amount during the 72-hour postoperative period varied significantly between BMI groups (p = 0.021), and the test for a linear decrease across groups was significant (p = 0.020). Twenty-four hour chest-tube output showed variation across all three BMI categories (p = 0.018) with chest-tube output decreasing with increasing obesity in a linear fashion (p = 0.006). Transfusion rate and amount indicate total blood loss is decreased in the obese, and chest-tube output findings give a direct measurable indicator of blood loss from the surgical site indicating increasing BMI is linearly correlated with decreasing postoperative bleeding. PMID:22654469

  20. Application of poultry processing industry waste: a strategy for vegetation growth in degraded soil.

    PubMed

    do Nascimento, Carla Danielle Vasconcelos; Pontes Filho, Roberto Albuquerque; Artur, Adriana Guirado; Costa, Mirian Cristina Gomes

    2015-02-01

    The disposal of poultry processing industry waste into the environment without proper care, can cause contamination. Agricultural monitored application is an alternative for disposal, considering its high amount of organic matter and its potential as a soil fertilizer. This study aimed to evaluate the potential of poultry processing industry waste to improve the conditions of a degraded soil from a desertification hotspot, contributing to leguminous tree seedlings growth. The study was carried out under greenhouse conditions in a randomized blocks design and a 4 × 2 factorial scheme with five replicates. The treatments featured four amounts of poultry processing industry waste (D1 = control 0 kg ha(-1); D2 = 1020.41 kg ha(-1); D3 = 2040.82 kg ha(-1); D4 = 4081.63 kg ha(-1)) and two leguminous tree species (Mimosa caesalpiniaefolia Benth and Leucaena leucocephala (Lam.) de Wit). The poultry processing industry waste was composed of poultry blood, grease, excrements and substances from the digestive system. Plant height, biomass production, plant nutrient accumulation and soil organic carbon were measured forty days after waste application. Leguminous tree seedlings growth was increased by waste amounts, especially M. caesalpiniaefolia Benth, with height increment of 29.5 cm for the waste amount of 1625 kg ha(-1), and L. leucocephala (Lam.) de Wit, with maximum height increment of 20 cm for the waste amount of 3814.3 kg ha(-1). M. caesalpiniaefolia Benth had greater initial growth, as well as greater biomass and nutrient accumulation compared with L. leucocephala (Lam.) de Wit. However, belowground biomass was similar between the evaluated species, resulting in higher root/shoot ratio for L. leucocephala (Lam.) de Wit. Soil organic carbon did not show significant response to waste amounts, but it did to leguminous tree seedlings growth, especially L. leucocephala (Lam.) de Wit. Poultry processing industry waste contributes to leguminous tree seedlings growth, indicating that it can be part of a long-term strategy to increase soil organic carbon in degraded soil from a desertification hotspot. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Effects of hydrolysis of milk glycerides on the antimutagenicity of a hexane extract of milk.

    PubMed

    Nadathur, S R; Zhou, L; Lowry, R R; Bakalinsky, A T

    1998-03-01

    Reconstituted nonfat dry milk was treated with different amounts of lipase from Pseudomonas fluorescens. Hexane extracts of treated milks were dissolved in dimethylsulfoxide and assayed for antimutagenicity using the Ames test (Salmonella typhimurium TA 100) against N-methyl, N'-nitro, N-nitrosoguanidine. Anti-N-methyl, N'-nitro, N-nitrosoguanidine activity increased significantly as the amount of added lipase increased. At the highest lipase concentration tested, activity increased 5-fold, suggesting that liberated fatty acids contributed to the increased antimutagenicity. The activities of mixtures of pure fatty acids on antimutagenesis were examined using the Ames test. At the lowest concentrations tested, mixtures of palmitic and stearic acids and mixtures of palmitic and isopalmitic acids exhibited greater activity than did the individual acids. At all doses tested, mixtures of the monoacylglycerides of palmitic and stearic acids exhibited the same activity as the individual components. Quantification of fatty acids in milk and yogurt by gas chromatography indicated a 2 to 20-fold greater content of free fatty acids in yogurt. The increase in free fatty acids may contribute to the increase in antimutagenicity of yogurt relative to that of milk.

  2. A new index quantifying the precipitation extremes

    NASA Astrophysics Data System (ADS)

    Busuioc, Aristita; Baciu, Madalina; Stoica, Cerasela

    2015-04-01

    Events of extreme precipitation have a great impact on society. They are associated with flooding, erosion and landslides.Various indices have been proposed to quantify these extreme events and they are mainly related to daily precipitation amount, which are usually available for long periods in many places over the world. The climate signal related to changes in the characteristics of precipitation extremes is different over various regions and it is dependent on the season and the index used to quantify the precipitation extremes. The climate model simulations and empirical evidence suggest that warmer climates, due to increased water vapour, lead to more intense precipitation events, even when the total annual precipitation is slightly reduced. It was suggested that there is a shift in the nature of precipitation events towards more intense and less frequent rains and increases in heavy rains are expected to occur in most places, even when the mean precipitation is not increasing. This conclusion was also proved for the Romanian territory in a recent study, showing a significant increasing trend of the rain shower frequency in the warm season over the entire country, despite no significant changes in the seasonal amount and the daily extremes. The shower events counted in that paper refer to all convective rains, including torrential ones giving high rainfall amount in very short time. The problem is to find an appropriate index to quantify such events in terms of their highest intensity in order to extract the maximum climate signal. In the present paper, a new index is proposed to quantify the maximum precipitation intensity in an extreme precipitation event, which could be directly related to the torrential rain intensity. This index is tested at nine Romanian stations (representing various physical-geographical conditions) and it is based on the continuous rainfall records derived from the graphical registrations (pluviograms) available at National Meteorological Administration in Romania. These types of records contain the rainfall intensity (mm/minute) over various intervals for which it remains constant. The maximum intensity for each continuous rain over the May-August interval has been calculated for each year. The corresponding time series over the 1951-2008 period have been analysed in terms of their long term trends and shifts in the mean; the results have been compared to those resulted from other rainfall indices based on daily and hourly data, computed over the same interval such as: total rainfall amount, maximum daily amount, contribution of total hourly amounts exceeding 10mm/day, contribution of daily amounts exceeding the 90th percentile, the 90th, 99th and 99.9th percentiles of 1-hour data . The results show that the proposed index exhibit a coherent and stronger climate signal (significant increase) for all analysed stations compared to the other indices associated to precipitation extremes, which show either no significant change or weaker signal. This finding shows that the proposed index is most appropriate to quantify the climate change signal of the precipitation extremes. We consider that this index is more naturally connected to the maximum intensity of a real rainfall event. The results presented is this study were funded by the Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISCDI) through the research project CLIMHYDEX, "Changes in climate extremes and associated impact in hydrological events in Romania", code PNII-ID-2011-2-0073 (http://climhydex.meteoromania.ro)

  3. 11 CFR 102.9 - Accounting for contributions and expenditures (2 U.S.C. 432(c)).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... (ii) A digital image of each check or written instrument. The political committee or other person... of receipt and amount of such contribution. (2) For contributions from any person whose contributions aggregate more than $200 during a calendar year, such account shall include the identification of the person...

  4. Informational Ambiguity and Survey Bias: Husbands' and Wives' Reports on Their Contribution to Their Families

    ERIC Educational Resources Information Center

    Tao, Hung-Lin

    2013-01-01

    The present study uses panel data models to control unobserved characteristics and to investigate how the presence of spouses in interviews influences reports regarding housework and earnings contributions. Both husbands and wives relatively overreport their housework contributions but do not overreport their earnings contributions. The amount of…

  5. Thesis Abstract Fermented milk elaborated with Camellia sinensis.

    PubMed

    Ribeiro, O A S; Silva, M I A; Boari, C A

    2016-05-13

    This study aimed to develop and to characterize fermented dairy beverage formulated with Camellia sinensis. The infusion was elaborated with the addiction of dehydrated leaves of C. sinensis in whey (1g/100g) which added in sweetened milk (10% sucrose w/w) coagulated by Streptococcus salivarius subspecies thermophilus and Lactobacillus delbrueckii subspecies bulgaricus in proportions of 10, 20, 30 and 40% (v/w). The control treatment consisted of yogurt added with sucrose (10% w/w). Analysis were performed to quantify dry mass, moisture, ash, protein, fat, sodium, acidity, total quantification of lactic acid bacteria, total antioxidant activity and viscosity at the initial time of production and at 15 and 30 days of storage. Chromatographic determination of volatile compounds and sensory tests of acceptance and consumption intention were conducted at the initial time of production. Dry matter content, moisture, ash and total count of lactic acid bacteria from fermented milk drink formulations were not significantly affected by the amount of infusion of C. sinensis. However, the content of protein, fat and sodium were significantly lower with the increase of the proportion of infusion incorporated into the product. Significant reduction in apparent viscosity occurs with the increase in the amount of infusion added. The total antioxidant activity of the formulations was significantly higher as higher were the amount of added infusion. The addition of infusion contributed to the diversification of volatile aroma and taste makers in the product. The formulation of fermented dairy drink with addition of 30% infusion C. sinensis was better evaluated in sensory tests, with greater acceptance and greater consumer intent of consumption.

  6. Ubiquitous anaerobic ammonium oxidation in inland waters of China: an overlooked nitrous oxide mitigation process

    PubMed Central

    Zhu, Guibing; Wang, Shanyun; Zhou, Leiliu; Wang, Yu; Zhao, Siyan; Xia, Chao; Wang, Weidong; Zhou, Rong; Wang, Chaoxu; Jetten, Mike S. M.; Hefting, Mariet M.; Yin, Chengqing; Qu, Jiuhui

    2015-01-01

    Denitrification has long been regarded as the only pathway for terrestrial nitrogen (N) loss to the atmosphere. Here we demonstrate that large-scale anaerobic ammonium oxidation (anammox), an overlooked N loss process alternative to denitrification which bypasses nitrous oxide (N2O), is ubiquitous in inland waters of China and contributes significantly to N loss. Anammox rates in aquatic systems show different levels (1.0–975.9 μmol N m−2 h−1, n = 256) with hotspots occurring at oxic-anoxic interfaces and harboring distinct biogeochemical and biogeographical features. Extrapolation of these results to the China-national level shows that anammox could contribute about 2.0 Tg N yr−1, which equals averagely 11.4% of the total N loss from China’s inland waters. Our results indicate that a significant amount of the nitrogen lost from inland waters bypasses denitrification, which is important for constructing more accurate climate models and may significantly reduce potential N2O emission risk at a large scale. PMID:26610807

  7. Synaptic noise is an information bottleneck in the inner retina during dynamic visual stimulation

    PubMed Central

    Freed, Michael A; Liang, Zhiyin

    2014-01-01

    In daylight, noise generated by cones determines the fidelity with which visual signals are initially encoded. Subsequent stages of visual processing require synapses from bipolar cells to ganglion cells, but whether these synapses generate a significant amount of noise was unknown. To characterize noise generated by these synapses, we recorded excitatory postsynaptic currents from mammalian retinal ganglion cells and subjected them to a computational noise analysis. The release of transmitter quanta at bipolar cell synapses contributed substantially to the noise variance found in the ganglion cell, causing a significant loss of fidelity from bipolar cell array to postsynaptic ganglion cell. Virtually all the remaining noise variance originated in the presynaptic circuit. Circuit noise had a frequency content similar to noise shared by ganglion cells but a very different frequency content from noise from bipolar cell synapses, indicating that these synapses constitute a source of independent noise not shared by ganglion cells. These findings contribute a picture of daylight retinal circuits where noise from cones and noise generated by synaptic transmission of cone signals significantly limit visual fidelity. PMID:24297850

  8. Beverage patterns and trends among school-aged children in the US, 1989-2008

    PubMed Central

    2011-01-01

    Background High intake of sugar-sweetened beverages in childhood is linked to increased risk of obesity and type II diabetes later in life. Using three nationally representative surveys of dietary intake, we investigated beverage patterns and trends among US school-aged children from 1989/91 to 2007/08. Methods 3, 583 participants ages 6-11 y old were included. We reported per capita trends in beverage consumption, percent consuming, and amount per consumer for the following categories of beverages: sugar-sweetened beverages (SSB), caloric nutritional beverages (CNB) and low calorie beverages (LCB). Statistically significant differences were tested using the Student's t test in Stata 11. Results While per capita kcal contribution from total beverages remained constant over the study period, per capita consumption of SSBs increased and CNBs decreased in similar magnitude. The substantial increase in consumption of certain SSBs, such as fruit drinks and soda, high fat high sugar milk, and sports drinks, coupled with the decrease in consumption of high fat low sugar milk was responsible for this shift. The percent consuming SSBs as well as the amount per consumer increased significantly over time. Per capita intake of total milk declined, but the caloric contribution from high fat high sugar milk increased substantially. Among ethnicities, important differences in consumption trends of certain SSBs and 100% juice indicate the complexity in determining strategies for children's beverage calorie reduction. Conclusions As upward trends of SSB consumption parallel increases in childhood obesity, educational and policy interventions should be considered. PMID:21962086

  9. 20 CFR 345.125 - Records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Records. 345.125 Section 345.125 Employees...' CONTRIBUTIONS AND CONTRIBUTION REPORTS Reporting and Collecting Contributions § 345.125 Records. Every employer..., keep such permanent records as are necessary to establish the total amount of compensation payable to...

  10. 77 FR 26175 - Section 42 Qualified Contract Provisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ... fees, operating deficit contributions, and legal, syndication, and accounting costs all are examples of... adjusted investor equity in the building, plus (III) other capital contributions not reflected in these... contributions, not including amounts described in (a) and (b); minus (d) cash distributions from (or available...

  11. Questionnaire survey on lifestyle of patients with nonalcoholic steatohepatitis

    PubMed Central

    Noto, Haruka; Tokushige, Katsutoshi; Hashimoto, Etsuko; Taniai, Makiko; Shiratori, Keiko

    2014-01-01

    Lack of exercise and excessive food intake are known to be the important causes of nonalcoholic steatohepatitis (NASH). To elucidate the relationship between lifestyle and NASH, we surveyed exercise and dietary habits, comparing them among 171 biopsy-proven NASH patients, 29 nonalcoholic fatty liver (NAFL) patients and 49 normal subjects. Dietary habits including the duration of dinner time, amount of rice at dinner, and weekly frequencies of meat, fries, Chinese noodles, sweets, and instant food consumption were significantly different in male NASH patients compared to normal male subjects. In women, differences were seen in the amount of rice at dinner, frequency of eating out, and proclivity for sweets. In male NASH patients, the frequency of physical exercise was significantly lower. The lifestyle tendencies of NASH were almost similar to those of NAFL. In the comparison between obese NASH and non-obese NASH, no clear lifestyle differences were found. In conclusion, the most striking result of this survey was that the lifestyle of males contributed significantly to the development of NASH. These results point to treatment of NASH in males. In female NASH patients, lifestyle differences were minimal, and the effects of other factors such as genetic background will need to be investigated. PMID:25411525

  12. Questionnaire survey on lifestyle of patients with nonalcoholic steatohepatitis.

    PubMed

    Noto, Haruka; Tokushige, Katsutoshi; Hashimoto, Etsuko; Taniai, Makiko; Shiratori, Keiko

    2014-11-01

    Lack of exercise and excessive food intake are known to be the important causes of nonalcoholic steatohepatitis (NASH). To elucidate the relationship between lifestyle and NASH, we surveyed exercise and dietary habits, comparing them among 171 biopsy-proven NASH patients, 29 nonalcoholic fatty liver (NAFL) patients and 49 normal subjects. Dietary habits including the duration of dinner time, amount of rice at dinner, and weekly frequencies of meat, fries, Chinese noodles, sweets, and instant food consumption were significantly different in male NASH patients compared to normal male subjects. In women, differences were seen in the amount of rice at dinner, frequency of eating out, and proclivity for sweets. In male NASH patients, the frequency of physical exercise was significantly lower. The lifestyle tendencies of NASH were almost similar to those of NAFL. In the comparison between obese NASH and non-obese NASH, no clear lifestyle differences were found. In conclusion, the most striking result of this survey was that the lifestyle of males contributed significantly to the development of NASH. These results point to treatment of NASH in males. In female NASH patients, lifestyle differences were minimal, and the effects of other factors such as genetic background will need to be investigated.

  13. Determinants of famous name processing speed: age of acquisition versus semantic connectedness.

    PubMed

    Smith-Spark, James H; Moore, Viv; Valentine, Tim

    2013-02-01

    The age of acquisition (AoA) and the amount of biographical information known about celebrities have been independently shown to influence the processing of famous people. In this experiment, we investigated the facilitative contribution of both factors to famous name processing. Twenty-four mature adults participated in a familiarity judgement task, in which the names of famous people were grouped orthogonally by AoA and by the number of bits of biographical information known about them (number of facts known; NoFK). Age of acquisition was found to have a significant effect on both reaction time (RT) and accuracy of response, but NoFK did not. The RT data also revealed a significant AoA×NoFK interaction. The amount of information known about a celebrity played a facilitative role in the processing of late-acquired, but not early-acquired, celebrities. Once AoA is controlled, it would appear that the semantic system ceases to have a significant overall influence on the processing of famous people. The pre-eminence of AoA over semantic connectedness is considered in the light of current theories of AoA and how their influence might interact. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. 11 CFR 102.8 - Receipt of contributions (2 U.S.C. 432(b)).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... later than 10 days after receipt, forward such contribution to the treasurer. If the amount of the contribution is in excess of $50, such person shall also forward to the treasurer the name and address of the... $200, such person shall forward the contribution, the identification of the contributor in accordance...

  15. 11 CFR 102.8 - Receipt of contributions (2 U.S.C. 432(b)).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... later than 10 days after receipt, forward such contribution to the treasurer. If the amount of the contribution is in excess of $50, such person shall also forward to the treasurer the name and address of the... $200, such person shall forward the contribution, the identification of the contributor in accordance...

  16. Espresso beverages of pure origin coffee: mineral characterization, contribution for mineral intake and geographical discrimination.

    PubMed

    Oliveira, Marta; Ramos, Sandra; Delerue-Matos, Cristina; Morais, Simone

    2015-06-15

    Espresso coffee beverages prepared from pure origin roasted ground coffees from the major world growing regions (Brazil, Ethiopia, Colombia, India, Mexico, Honduras, Guatemala, Papua New Guinea, Kenya, Cuba, Timor, Mussulo and China) were characterized and compared in terms of their mineral content. Regular consumption of one cup of espresso contributes to a daily mineral intake varying from 0.002% (sodium; Central America) to 8.73% (potassium; Asia). The mineral profiles of the espresso beverages revealed significant inter- and intra-continental differences. South American pure origin coffees are on average richer in the analyzed elements except for calcium, while samples from Central America have generally lower mineral amounts (except for manganese). Manganese displayed significant differences (p<0.05) among the countries of each characterized continent. Intercontinental and inter-country discrimination between the major world coffee producers were achieved by applying canonical discriminant analysis. Manganese and calcium were found to be the best chemical descriptors for origin. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Can Arctic sea-ice melt be explained by atmospheric meridional transports? (Invited)

    NASA Astrophysics Data System (ADS)

    Tjernstrom, M. K.; Graversen, R. G.

    2010-12-01

    The Arctic summer sea ice is melting away at an alarming rate, and it is now expected that an principally sea-ice free Arctic summer will occur much earlier than projected by the IPCC AR4 models. At the same time Arctic near-surface temperatures are rising at a rate much faster than the global average. The processes responsible for these changes are debated and many claim that local feedbacks, such as the surface albedo feedback, are the main culprits while other argue that remote effects, such as atmospheric circulation changes on synoptic and hemispheric scales, are the most important. We will explore the effects of the meridional transport by synoptic and larger scale atmospheric circulation on recent changes, using reanalysis data. It will be illustarated how this transport can contribute significant amounts of sensible heat, but also of atmospheric moisture such that local cloud feedbacks as well as the direct greenhouse effect of the water vapor contributes significantly to the surface energy balance over the Arctic polar cap.

  18. A fiber-based constitutive model predicts changes in amount and organization of matrix proteins with development and disease in the mouse aorta

    PubMed Central

    Cheng, Jeffrey K.; Stoilov, Ivan; Mecham, Robert P.

    2013-01-01

    Decreased elastin in mice (Eln+/−) yields a functioning vascular system with elevated blood pressure and increased arterial stiffness that is morphologically distinct from wild-type mice (WT). Yet, function is retained enough that there is no appreciable effect on life span and some mechanical properties are maintained constant. It is not understood how the mouse modifies the normal developmental process to produce a functioning vascular system despite a deficiency in elastin. To quantify changes in mechanical properties, we have applied a fiber-based constitutive model to mechanical data from the ascending aorta during postnatal development of WT and Eln+/− mice. Results indicate that the fiber-based constitutive model is capable of distinguishing elastin amounts and identifying trends during development. We observe an increase in predicted circumferential stress contribution from elastin with age, which correlates with increased elastin amounts from protein quantification data. The model also predicts changes in the unloaded collagen fiber orientation with age, which must be verified in future work. In Eln+/− mice, elastin amounts are decreased at each age, along with the predicted circumferential stress contribution of elastin. Collagen amounts in Eln+/− aorta are comparable to WT, but the predicted circumferential stress contribution of collagen is increased. This may be due to altered organization or structure of the collagen fibers. Relating quantifiable changes in arterial mechanics with changes in extracellular matrix (ECM) protein amounts will help in understanding developmental remodeling and in producing treatments for human diseases affecting ECM proteins. PMID:22790326

  19. Impact of relativistic effects on cosmological parameter estimation

    NASA Astrophysics Data System (ADS)

    Lorenz, Christiane S.; Alonso, David; Ferreira, Pedro G.

    2018-01-01

    Future surveys will access large volumes of space and hence very long wavelength fluctuations of the matter density and gravitational field. It has been argued that the set of secondary effects that affect the galaxy distribution, relativistic in nature, will bring new, complementary cosmological constraints. We study this claim in detail by focusing on a subset of wide-area future surveys: Stage-4 cosmic microwave background experiments and photometric redshift surveys. In particular, we look at the magnification lensing contribution to galaxy clustering and general-relativistic corrections to all observables. We quantify the amount of information encoded in these effects in terms of the tightening of the final cosmological constraints as well as the potential bias in inferred parameters associated with neglecting them. We do so for a wide range of cosmological parameters, covering neutrino masses, standard dark-energy parametrizations and scalar-tensor gravity theories. Our results show that, while the effect of lensing magnification to number counts does not contain a significant amount of information when galaxy clustering is combined with cosmic shear measurements, this contribution does play a significant role in biasing estimates on a host of parameter families if unaccounted for. Since the amplitude of the magnification term is controlled by the slope of the source number counts with apparent magnitude, s (z ), we also estimate the accuracy to which this quantity must be known to avoid systematic parameter biases, finding that future surveys will need to determine s (z ) to the ˜5 %- 10 % level. On the contrary, large-scale general-relativistic corrections are irrelevant both in terms of information content and parameter bias for most cosmological parameters but significant for the level of primordial non-Gaussianity.

  20. 49 CFR 213.119 - Continuous welded rail (CWR); plan contents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... following items: (i) Loose, bent, or missing joint bolts; (ii) Rail end batter or mismatch that contributes... amount and length of rail end batter or ramp on each rail end; the amount of tread mismatch; the vertical...

  1. 49 CFR 213.119 - Continuous welded rail (CWR); plan contents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... following items: (i) Loose, bent, or missing joint bolts; (ii) Rail end batter or mismatch that contributes... amount and length of rail end batter or ramp on each rail end; the amount of tread mismatch; the vertical...

  2. Radiation dose from reentrant electrons

    NASA Technical Reports Server (NTRS)

    Badhwar, G. D.; Watts, J.; Cleghorn, T. E.

    2001-01-01

    In estimating the crew exposures during an extra vehicular activity (EVA), the contribution of reentrant electrons has always been neglected. Although the flux of these electrons is small compared to the flux of trapped electrons, their energy spectrum extends to several GeV compared to about 7 MeV for trapped electrons. This is also true of splash electrons. Using the measured reentrant electron energy spectra, it is shown that the dose contribution of these electrons to the blood forming organs (BFO) is more that 10 times greater than that from the trapped electrons. The calculations also show that the dose-depth response is a very slowly changing function of depth, and thus adding reasonable amounts of additional shielding would not significantly lower the dose to BFO. Published by Elsevier Science Ltd.

  3. Who cares and how much? The imputed economic contribution to the Canadian healthcare system of middle-aged and older unpaid caregivers providing care to the elderly.

    PubMed

    Hollander, Marcus J; Liu, Guiping; Chappell, Neena L

    2009-01-01

    Canadians provide significant amounts of unpaid care to elderly family members and friends with long-term health problems. While some information is available on the nature of the tasks unpaid caregivers perform, and the amounts of time they spend on these tasks, the contribution of unpaid caregivers is often hidden. (It is recognized that some caregiving may be for short periods of time or may entail matters better described as "help" or "assistance," such as providing transportation. However, we use caregiving to cover the full range of unpaid care provided from some basic help to personal care.) Aggregate estimates of the market costs to replace the unpaid care provided are important to governments for policy development as they provide a means to situate the contributions of unpaid caregivers within Canada's healthcare system. The purpose of this study was to obtain an assessment of the imputed costs of replacing the unpaid care provided by Canadians to the elderly. (Imputed costs is used to refer to costs that would be incurred if the care provided by an unpaid caregiver was, instead, provided by a paid caregiver, on a direct hour-for-hour substitution basis.) The economic value of unpaid care as understood in this study is defined as the cost to replace the services provided by unpaid caregivers at rates for paid care providers.

  4. Coverage of Russian psychological contributions in American psychology textbooks.

    PubMed

    Aleksandrova-Howell, Maria; Abramson, Charles I; Craig, David Philip Arthur

    2012-01-01

    Internationalizing psychology is an important component of current globalization trends. American textbooks on the history of psychology and introductory psychology were surveyed for the presence of historical and contemporary important Russian psychologists to assess the current status of Russian-American crossfertilization. Of a list of 97 important Russian psychologists, as determined by the editors of the Russian journal Methodology and History in Psychology, less than 22% are mentioned in the reviewed texts. The most common names were Pavlov, Luria, and Vygotsky. As the internet is arguably the single most important factor affecting the increase of international communication and dissemination of knowledge, we also searched for these 97 names on various websites, most notably Wikipedia and Google. Forty-one internet sites contained some amount of biographical information about Russian psychologists. On Wikipedia, 14 Russian psychologists had articles documenting biographical information. We also developed a rubric to determine the amount of information available on the internet for these psychologists and compared Wikipedia's mean score with various other websites. Wikipedia pages on average had a significantly higher score than the rest of the internet. Recommendations to improve Russian coverage in America are provided and include: (1) developing pages on Wikipedia and other virtual venues highlighting Russian contributions, (2) soliciting articles for US journals from Russian psychologists, and (3) incorporating Russian contributions in introductory and historical textbooks. We provide a partial bibliography of Russian contributions that can be used by authors of such textbooks. We would like to thank Dr Viktor Fedorovich Petrenko and Dr Igor Nikolaevich Karitsky from the journal Methodology and History of Psychology for supplying the names of the Russian psychologists. We would also like to express our appreciation to Robert García for reviewing and editing an earlier version of this manuscript.

  5. 24 CFR 904.305 - Funding of HBA.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... services, the LHA shall make cash contributions for operating expenses of the HBA, in the amount provided for in paragraph (b) of this section. Until the project goes into management, these contributions...). Thereafter, these contributions shall be provided for in the annual operating budgets of the LHA. (b) The...

  6. Avocado, sunflower and olive oils as replacers of pork back-fat in burger patties: effect on lipid composition, oxidative stability and quality traits.

    PubMed

    Rodríguez-Carpena, J G; Morcuende, D; Estévez, M

    2012-01-01

    The present study investigates the effects of avocado, sunflower and olive oils used as back-fat replacers, on the fatty acid composition, oxidative stability, volatiles profile and color and texture properties of cooked pork patties. The vegetable oils modified the fatty acid profiles of the patties by lowering the percentages of SFA (from 36.96% to ~25.30%) and reducing the atherogenic index (from 0.41 to ~0.24). Vegetable oils had higher amounts of antioxidant compounds such as tocopherols (10.8-53.9 mg/100 g) than back-fat (5.9 mg/100 g). Consistently, patties manufactured with the oils had significantly lower amounts of lipid and protein oxidation products than control patties. Avocado oil contributed with specific aroma-active terpenes to patties and had a significant impact on particular color and texture parameters. The results from this study highlight the technological applications of the vegetable oils as food ingredients in the design of healthier meat commodities. Copyright © 2011 Elsevier Ltd. All rights reserved.

  7. Strategy intervention in spatial voluntary public goods games

    NASA Astrophysics Data System (ADS)

    Yang, Luhe; Xu, Zhaojin; Zhang, Lianzhong; Yang, Duoxing

    2018-04-01

    It is well known that punishment has been considered to enhance cooperation based on empirical and theoretical studies. An important question arises over the existence of the “second-order” problems, which result from the interactions between individuals. In this paper, we propose strategy intervention as a new mechanism in spatial voluntary public goods game, in which individuals only know their own payoffs. By virtue of centralized institution, the defectors may reserve amounts of probabilities to contribute to the common pool with a certain amount of investments. The centralized institution is established costly by all the participants to enforce the intervention rather than peer punishment. We find that the number of cooperators (defectors) decreases (increases) with weak intervention, which contrasts our intuition. Loners vanish and cooperation emerges significantly, as the level of intervention reaches a threshold. We give an accurate range of intervention leading to full cooperation, and demonstrate that at partial cooperation state, proper intervention can remarkably increase income accumulations of individuals, between which there exists smaller income gap in contrast to typical models. We highlight the significance of intervention enforced by a higher authority for maintaining social stability.

  8. Mathematical Modelling of Allelopathy: IV. Assessment of Contributions of Competition and Allelopathy to Interference by Barley

    PubMed Central

    Liu, De Li; An, Min; Johnson, I.R.; Lovett, J.V.

    2005-01-01

    One of the main challenges to the research on allelopathy is technically the separation of allelopathic effect from competition, and quantitatively, the assessment of the contribution of each component to overall interference. A simple mathematical model is proposed to calculate the contribution of allelopathy and competition to interference. As an example of applying the quantitative model to interference by barley (Hordeum vulgare cv. Triumph), the approach used was an addition of allelopathic effect, by an equivalent amount, to the environment of the test plant (white mustard, Sinapis alba), rather than elimination of competition. Experiments were conducted in glasshouse to determine the magnitude of the contributions of allelopathy and competition to interference by barley. The leachates of living barley roots significantly reduced the total dry weight of white mustard. The model involved the calculation of adjusted densities to an equivalent basis for modelling the contribution of allelopathy and competition to total interference. The results showed that allelopathy contributed 40%, 37% and 43% to interference by barley at 6, 12 and 18 white mustard pot−1. The consistency in magnitude of the calculated contribution of allelopathic effect by barley across various densities of receiver plant suggested that the adjusted equivalent density is effective and that the model is able to assess the contribution of each component of interference regardless of the density of receiver plant. PMID:19330162

  9. Biofilms' contribution to organic carbon in salt marsh sediments

    NASA Astrophysics Data System (ADS)

    Valentine, K.; Quirk, T. E.; Mariotti, G.; Hotard, A.

    2017-12-01

    Coastal salt marshes are productive environments with high potential for carbon (C) accumulation. Organic C in salt marsh sediment is typically attributed to plant biomass. Recent field measurements, however, suggest that biofilms - mainly composed of benthic diatoms and their secretion - also contribute to basal C in these environments and can be important contributors to marsh productivity, C cycling, and potentially, C sequestration. The potential for biofilms to soil organic C and the influence of mineral sedimentation of biofilm-based C accumulation is unknown. We conducted controlled laboratory experiments to test (1) whether biofilms add measurable amounts of organic C to the sediment and (2) the effect of mineral sedimentation rate on the amount of biofilm-based C accumulation. Settled beds of pure bentonite mud were created in 10-cm-wide cylinders. Each cylinder was inoculated with biofilms collected from a marsh in Louisiana. A small amount of mud was added weekly for 11 weeks. Control experiments without biofilms were also performed. Biofilms were grown with a 12/12 hours cycle, with a gentle mixing of the water column that did not cause sediment resuspension, with a nutrient-rich medium that was exchanged weekly, and in the absence of metazoan grazing. At the end of the experiment, the sediment columns were analyzed for depth-integrated chl-a, loss on ignition (LOI), and total organic carbon (TOC). Chl-a values ranged from 26-113 mg/cm2, LOI values ranged from 86-456 g/m2/yr, and TOC values ranged from 31-211 g/m2/yr. All three of these metrics (chl-a, LOI, and TOC) increased with the rate of mineral sedimentation. These results show that biofilms, in the absence of erosion and grazing, can significantly contribute to C accumulation in salt marshes, especially with high rates of mineral sedimentation. Given the short time scale of the experiment, the increase in organic C accumulation with the rate of sedimentation is attributed to stimulated biofilm production rather than increased C preservation.

  10. A first French assessment of population exposure to tetrachloroethylene from small dry-cleaning facilities.

    PubMed

    Chiappini, L; Delery, L; Leoz, E; Brouard, B; Fagault, Y

    2009-06-01

    Used as a solvent in the dry-cleaning industry, tetrachloroethylene (C(2)Cl(4)) can be a pollutant of residential indoor air, which can cause long-term harmful exposures because of its neurotoxicity and probable carcinogenicity. In France, dry-cleaning facilities are integrated in urban environments (shopping malls, residential buildings) and can contribute to C(2)Cl(4) exposure for customers and residents. This exploratory work presents the results from five studies carried out in one shopping mall and four residential buildings housing a dry-cleaning facility. These studies involved dry-cleaning machines fitted with a Carbon Adsorber and unfitted, with or without Air Exhaust System. Samples were collected in the cleaning facilities and in the apartments located above with passive samplers allowing measurement of time-integrated concentrations on a 7 days sampling period. It has obviously shown the degradation of indoor air quality in these environments and underlined the contributing role of the machine technology and ventilation system on the amount of released C(2)Cl(4) in the indoor air. To temper these results, it must be pointed out that some parameters (building insulation, amount of solvent used...) which would influence C(2)Cl(4) fugitive release have not been quantified and should be looked at in further studies. In France, dry-cleaning facilities are frequently integrated in urban environments (large shopping malls or residential buildings) and can significantly contribute to tetrachloroethylene (C(2)Cl(4)) population exposure. The amount of fugitive releases in these environments depends on several parameters such as the dry-cleaning machine technology (fitted or unfitted with a carbon adsorber) and the ventilation (air exhaust system). To reduce C(2)Cl(4) exposure in residential buildings and other indoor environments with on-site dry cleaners, carbon adsorber unequipped machine should be replaced by newer technology and dry cleaners should be equipped with mechanical air exhaust systems.

  11. Acquisition Research: Creating Synergy for Informed Change. Proceedings of the Annual Acquisition Research Symposium (4th) Held in Monterey, California on 16-17 May 2007. Volume 1: Wednesday Sessions

    DTIC Science & Technology

    2007-04-30

    systems were impacted by mergers, a greater proportion of them experienced a reduction in costs rather than an increase in costs. Fifth, when the...technical teams represent a significant proportion of the team activities within the Department of Defense (DoD) acquisition community and corporate...of precision necessary to allocate value (e.g., revenue, outputs) to individual managers in proportion to the amount they contribute to the

  12. Payload dose rate from direct beam radiation and exhaust gas fission products. [for nuclear engine for rocket vehicles

    NASA Technical Reports Server (NTRS)

    Capo, M. A.; Mickle, R.

    1975-01-01

    A study was made to determine the dose rate at the payload position in the NERVA System (1) due to direct beam radiation and (2) due to the possible effect of fission products contained in the exhaust gases for various amounts of hydrogen propellant in the tank. Results indicate that the gamma radiation is more significant than the neutron flux. Under different assumptions the gamma contribution from the exhaust gases was 10 to 25 percent of total gamma flux.

  13. Effects of land use and hydrogeology on the water quality of alluvial aquifers in eastern Iowa and southern Minnesota, 1997

    USGS Publications Warehouse

    Savoca, Mark E.; Sadorf, Eric M.; Linhart, S. Mike; Akers, Kim K.B.

    2000-01-01

    Factors other than land use may contribute to observed differences in water quality between and within agricultural and urban areas. Nitrate, atrazine, deethylatrazine, and deisopropylatrazine concentrations were significantly higher in shallow wells with sample intervals nearer the water table and in wells with thinner cumulative clay thickness above the sample intervals. These relations suggest that longer flow paths allow for greater residence time and increase opportunities for sorption, degradation, and dispersion, which may contribute to decreases in nutrient and pesticide concentrations with depth. Nitrogen speciation was influenced by redox conditions. Nitrate concentrations were significantly higher in ground water with dissolved-oxygen concentrations in excess of 0.5 milligram per liter. Ammonia concentrations were higher in ground water with dissolved-oxygen concentrations of 0.5 milligram per liter or less; however, this relation was not statistically significant. The amount of available organic matter may limit denitrification rates. Elevated nitrate concentrations (greater than 2.0 mg/L) were significantly related to lower dissolved organic carbon concentrations in water samples from both agricultural and urban areas. A similar relation between nitrate concentrations (in water) and organic carbon concentrations (in aquifer material) also was observed but was not statistically significant.

  14. Environmental factors contributed to circannual rhythm of semen quality.

    PubMed

    Mao, Huan; Feng, Lei; Yang, Wan-Xi

    2017-01-01

    We investigated whether human semen parameters present circannual rhythm or not, and whether environmental factors exert on semen quality. This retrospective study used data of patients mainly from Reproductive Medicine Center and Urology and Andrology Clinic of a general hospital in China. Sperm concentration and motility were measured by computer aided sperm analysis (CASA). Sperm morphology was scored based on the strict criteria (WHO, 2010). The Kruskal-Wallis rank test was used to investigate the relationship between semen parameters and season/month. Partial correlation coefficients were used to analyze the relationship between semen parameters and environmental factors. In this study, we found that sperm concentration and total amount per ejaculate were significantly lower in summer and higher in winter. But, sperm progressive motility and motility were significantly higher in spring and summer (from March to June), lower in autumn and winter (September and October). Unexpectedly, normal sperm morphology and mixed agglutination reaction (MAR) positive rate didn't vary along with season or month. Furthermore, temperature was negatively related to sperm concentration and total amount per ejaculate. Precipitation was positively associated with progressive motility and normal sperm morphology, but negatively related to sperm head defect percentage. The length of sunlight was positively related to progressive motility. The Air Quality Index (AQI) was positively associated with semen volume and sperm total amount per ejaculate. These suggest seasonal and monthly variation underlying some semen parameters.

  15. Does industrial waste taxation contribute to reduction of landfilled waste? Dynamic panel analysis considering industrial waste category in Japan.

    PubMed

    Sasao, Toshiaki

    2014-11-01

    Waste taxes, such as landfill and incineration taxes, have emerged as a popular option in developed countries to promote the 3Rs (reduce, reuse, and recycle). However, few studies have examined the effectiveness of waste taxes. In addition, quite a few studies have considered both dynamic relationships among dependent variables and unobserved individual heterogeneity among the jurisdictions. If dependent variables are persistent, omitted variables cause a bias, or common characteristics exist across the jurisdictions that have introduced waste taxes, the standard fixed effects model may lead to biased estimation results and misunderstood causal relationships. In addition, most existing studies have examined waste in terms of total amounts rather than by categories. Even if significant reductions in total waste amounts are not observed, some reduction within each category may, nevertheless, become evident. Therefore, this study analyzes the effects of industrial waste taxation on quantities of waste in landfill in Japan by applying the bias-corrected least-squares dummy variable (LSDVC) estimators; the general method of moments (difference GMM); and the system GMM. In addition, the study investigates effect differences attributable to industrial waste categories and taxation types. This paper shows that industrial waste taxes in Japan have minimal, significant effects on the reduction of final disposal amounts thus far, considering dynamic relationships and waste categories. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Thoron (220Rn) in the indoor environment and work places

    NASA Astrophysics Data System (ADS)

    Ramachandran, T. V.; Sahoo, B. K.

    2009-08-01

    Ever since studies on uranium miners established the presence of a positive risk coefficient for the occurrence of lung cancer in miners exposed to elevated levels of 222Rn and its progeny, there was a great upsurge of interest in the measurement of 222Rn in the environment. Subsequently, considerable data is being generated on the levels of 222Rn in the environment across the worlds and is being periodically reported by UNSCEAR reports. In contrast to this, data pertaining to 220Rn in indoors and workplace environment is scaree due to the genral perception that its levels are negligible due to its shorter half life, and subsequently its contribution to the total inhalation dose is ignored, in the presence of other significant sources of natural radiation. This may not be true. Globally many locations have higher levels of natural background radiation due to elevated levels of primordial radio nuclides in the soil and their decay products like radon (222Rn), and thoron (220Rn) in the environment. Of late, technologically enhanced naturally occurring radioactive material has also contributed to the burden of background radiation. It is estimated that inhalation of 222Rn, 220Rn and their short lived progenies contribute more than 54% of the total natural background radiation dose received by the general population. 220Rn problem exists in industries which use thorium nitrate. Including India, lamps using thoriated gas mantles are still being used for indoor and outdoor lighting and by hawkers in rural as well as urban areas. Considering the fact that large amount of thorium nitrate is being handled by these industries, contribution to the inhalation dose of workers from 220Rn gas emanated and build up of the progeny in ambient air may also be quite significant. In this paper current status of 220Rn levels in the indoor environment and workplaces as well as in other industries where large amount of 232Th is being handled is being summarized. Methods of measurement and reported levels are also summarized.

  17. Significance of non-sinking particulate organic carbon and dark CO2 fixation to heterotrophic carbon demand in the mesopelagic northeast Atlantic

    NASA Astrophysics Data System (ADS)

    Baltar, Federico; Arístegui, Javier; Sintes, Eva; Gasol, Josep M.; Reinthaler, Thomas; Herndl, Gerhard J.

    2010-05-01

    It is generally assumed that sinking particulate organic carbon (POC) constitutes the main source of organic carbon supply to the deep ocean's food webs. However, a major discrepancy between the rates of sinking POC supply (collected with sediment traps) and the prokaryotic organic carbon demand (the total amount of carbon required to sustain the heterotrophic metabolism of the prokaryotes; i.e., production plus respiration, PCD) of deep-water communities has been consistently reported for the dark realm of the global ocean. While the amount of sinking POC flux declines exponentially with depth, the concentration of suspended, buoyant non-sinking POC (nsPOC; obtained with oceanographic bottles) exhibits only small variations with depth in the (sub)tropical Northeast Atlantic. Based on available data for the North Atlantic we show here that the sinking POC flux would contribute only 4-12% of the PCD in the mesopelagic realm (depending on the primary production rate in surface waters). The amount of nsPOC potentially available to heterotrophic prokaryotes in the mesopelagic realm can be partly replenished by dark dissolved inorganic carbon fixation contributing between 12% to 72% to the PCD daily. Taken together, there is evidence that the mesopelagic microheterotrophic biota is more dependent on the nsPOC pool than on the sinking POC supply. Hence, the enigmatic major mismatch between the organic carbon demand of the deep-water heterotrophic microbiota and the POC supply rates might be substantially smaller by including the potentially available nsPOC and its autochthonous production in oceanic carbon cycling models.

  18. Plan choice, health insurance cost and premium sharing.

    PubMed

    Kosteas, Vasilios D; Renna, Francesco

    2014-05-01

    We develop a model of premium sharing for firms that offer multiple insurance plans. We assume that firms offer one low quality plan and one high quality plan. Under the assumption of wage rigidities we found that the employee's contribution to each plan is an increasing function of that plan's premium. The effect of the other plan's premium is ambiguous. We test our hypothesis using data from the Employer Health Benefit Survey. Restricting the analysis to firms that offer both HMO and PPO plans, we measure the amount of the premium passed on to employees in response to a change in both premiums. We find evidence of large and positive effects of the increase in the plan's premium on the amount of the premium passed on to employees. The effect of the alternative plan's premium is negative but statistically significant only for the PPO plans. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  20. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  1. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  2. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  3. 26 CFR 1.118-2 - Contribution in aid of construction.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... adjusted basis of the water facility from zero to $20,000. (e) Statute of limitations—(1) Extension of... Contribution in aid of construction. (a) Special rule for water and sewerage disposal utilities—(1) In general... public utility that provides water or sewerage disposal services if— (i) The amount is a contribution in...

  4. 26 CFR 1.170A-1 - Charitable, etc., contributions and gifts; allowance of deduction.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... taxable year is allowable as a deduction in computing taxable income irrespective of the method of..., and the deduction for, amounts paid to maintain certain students as members of the taxpayer's... contributed property which are incurred in the year of contribution and would, under the method of accounting...

  5. 26 CFR 1.404(a)-7 - Pension and annuity plans; contributions in excess of limitations under section 404(a)(1...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... to succeeding years 15,000 Taxable Year Ending Dec. 31, 1956 Amount of contributions paid in year $10... section 404(a)(1)(D). When contributions paid by an employer in a taxable year to or under a pension or... excess contributions are carried over and are deductible in succeeding taxable years of the employer in...

  6. Crushing of Subglacial Lake Sediment as a Source of Bio-utilisable Gases.

    NASA Astrophysics Data System (ADS)

    Gill Olivas, B.; Telling, J.; Michaud, A. B.; Skidmore, M. L.; Priscu, J. C.; Tranter, M.

    2017-12-01

    Recent research has shown microbial ecosystems exist under glaciers and ice sheets. The sources of energy to support these ecosystems are still not fully understood, particularly beneath the Antarctic Ice Sheet, where direct access to the atmosphere and in-washed organic matter and oxidising agents does not occur. Hence, sub-ice sheet energy sources are restricted to those in subglacial environments, except for ice-margin environments. This study focuses on sediments from Subglacial Lake Whillans (SLW), the first subglacial lake to be directly and cleanly sampled. Sediment from three depths in a shallow core extracted from SLW were used to assess the possible energy contributions from mechanochemical reactions to this subglacial ecosystem. To do this, the samples were crushed under an anoxic atmosphere using a ball mill. The sediments were then transferred into serum bottles under anoxic conditions. They were wetted and the headspace gas was subsequently sampled and analysed during a 40 day incubation. Results show the release of substantial amounts of hydrogen, which could potentially serve as an abiotic source of energy to microbes, in particular, methanogenic archaea. Significant amounts of short chain hydrocarbons (including methane and ethylene), possibly from the reactivation of ancient organic carbon, were also observed. Crushed samples showed a significant concentration of hydrogen peroxide produced on contact with water, as well as significant amounts of Si radicals, showing comminution of these sediments unlocks the potential for a wide range of redox conditions and reactions to develop within glacially eroded sediment under ice. This in turn provides a previously overlooked source of nutrients and energy for microbes to utilise.

  7. Bilingualism as a contributor to cognitive reserve: evidence from brain atrophy in Alzheimer's disease.

    PubMed

    Schweizer, Tom A; Ware, Jenna; Fischer, Corinne E; Craik, Fergus I M; Bialystok, Ellen

    2012-09-01

    Much of the research on delaying the onset of symptoms of Alzheimer's disease (AD) has focused on pharmacotherapy, but environmental factors have also been acknowledged to play a significant role. Bilingualism may be one factor contributing to 'cognitive reserve' (CR) and therefore to a delay in symptom onset. If bilingualism is protective, then the brains of bilinguals should show greater atrophy in relevant areas, since their enhanced CR enables them to function at a higher level than would be predicted from their level of disease. We analyzed a number of linear measurements of brain atrophy from the computed tomography (CT) scans of monolingual and bilingual patients diagnosed with probable AD who were matched on level of cognitive performance and years of education. Bilingual patients with AD exhibited substantially greater amounts of brain atrophy than monolingual patients in areas traditionally used to distinguish AD patients from healthy controls, specifically, the radial width of the temporal horn and the temporal horn ratio. Other measures of brain atrophy were comparable for the two groups. Bilingualism appears to contribute to increased CR, thereby delaying the onset of AD and requiring the presence of greater amounts of neuropathology before the disease is manifest. Copyright © 2011 Elsevier Srl. All rights reserved.

  8. 40 CFR 440.131 - General provisions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... permitted. (e) Groundwater infiltration provision. In the event a new source subject to a no discharge requirement can demonstrate that groundwater infiltration contributes a substantial amount of water to the... volume of water equivalent to the amount of groundwater infiltration. This discharge shall be subject to...

  9. 40 CFR 440.131 - General provisions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... permitted. (e) Groundwater infiltration provision. In the event a new source subject to a no discharge requirement can demonstrate that groundwater infiltration contributes a substantial amount of water to the... volume of water equivalent to the amount of groundwater infiltration. This discharge shall be subject to...

  10. 40 CFR 440.131 - General provisions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... permitted. (e) Groundwater infiltration provision. In the event a new source subject to a no discharge requirement can demonstrate that groundwater infiltration contributes a substantial amount of water to the... volume of water equivalent to the amount of groundwater infiltration. This discharge shall be subject to...

  11. Differential exudation of two benzoxazinoids--one of the determining factors for seedling allelopathy of Triticeae species.

    PubMed

    Belz, Regina G; Hurle, Karl

    2005-01-26

    Benzoxazinoids (Bx) are natural phytotoxins that function as chemical defense compounds in several species. The release of Bx by intact plant roots associated these compounds with root allelopathy in Triticeae species; however, the significance of exudate concentrations of Bx for plant-plant interactions is still a controversial question. A biological screening of 146 cultivars of four Triticeae species (Triticum aestivum L., Triticum durum Desf., Triticum spelta L., and Secale cereale L.) demonstrated a high cultivar dependence to suppress the root growth of Sinapis alba L. by root allelopathy in a dose-response bioassay. Only a few cultivars possessed a marked high or low allelopathic activity, whereby high-performance liquid chromatography-diode array detection analysis of root exudates revealed that these cultivars differed considerably in their ability to exude the two Bx aglucones, DIBOA [2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one] and DIMBOA [2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one]. The total amount of DIBOA and DIMBOA exuded showed a significant correlation to the growth inhibition in bioassay with a statistically estimated contribution to the overall allelopathic effect of 48-72%. In a bioassay with pure phytotoxins, Bx concentrations consistent with the amounts quantified in the screening bioassay caused detrimental effects on S. alba and almost reproduced the statistically estimated contribution. The observed causal association between the allelopathic activity under laboratory conditions and the exudate concentrations of Bx suggests that this association might have implications for the interference of Triticeae species in natural plant communities.

  12. “Raising Him … to Pull His Own Weight”: Boys’ Household Work in Single- Mother Households

    PubMed Central

    Berridge, Clara W.; Romich, Jennifer L.

    2012-01-01

    In this study, the authors examine boys’ household work in low- and moderate-income single-mother families. Through describing the work that boys do, why they do this work, and the meaning that they and their mothers give to this work, they add to the understanding of housework as an arena for gender role reproduction or interruption. Their data reveal that adolescent boys did a significant amount of work and took pride in their competence. Mothers grounded their expectations of boys’ household contributions in life experience. They both needed their sons’ day-to-day contributions and wanted their sons to grow into men who were competent around the house and good partners. In demanding household work from their sons, these single mothers themselves work to undermine the traditional gendered division of such labor. PMID:22773881

  13. Autism risk factors: genes, environment, and gene-environment interactions

    PubMed Central

    Chaste, Pauline; Leboyer, Marion

    2012-01-01

    The aim of this review is to summarize the key findings from genetic and epidemiological research, which show that autism is a complex disorder resulting from the combination of genetic and environmental factors. Remarkable advances in the knowledge of genetic causes of autism have resulted from the great efforts made in the field of genetics. The identification of specific alleles contributing to the autism spectrum has supplied important pieces for the autism puzzle. However, many questions remain unanswered, and new questions are raised by recent results. Moreover, given the amount of evidence supporting a significant contribution of environmental factors to autism risk, it is now clear that the search for environmental factors should be reinforced. One aspect of this search that has been neglected so far is the study of interactions between genes and environmental factors. PMID:23226953

  14. Organic matter in a subtropical mangrove-estuary subjected to wastewater discharge: Origin and utilisation by two macrozoobenthic species

    NASA Astrophysics Data System (ADS)

    Meziane, Tarik; Tsuchiya, Makoto

    2002-02-01

    Total lipid amounts, fatty acid signature analysis, and C:N measurements were used to investigate the sources of organic matter in an Okinawan estuary (Okukubi, Japan) during the 1999 rainy season. This estuary has a mangrove forest and receives agricultural wastewater. Highest concentrations of total lipids and lowest C:N values were simultaneously found near the pipe where the agricultural water is discharged. Fatty acid profiles in the sediments varied among the stations, indicating differences in the contributing organic sources. Small amounts of lipids and low relative contributions of long-chain fatty acids, markers of vascular plants, were found at stations within and adjacent to the mangrove. These results indicate that the export of organic matter from the mangrove litter to the intertidal flat was limited and spatially restricted. The wastewater seems to induce high amounts of bacteria, macroalgae and benthic diatoms, as indicated by their respective fatty acid markers. The fatty acid profiles of the tissues of two dominant intertidal invertebrates, the crab Uca vocans and the gastropod Terebralia sulcata, indicated that their diet was largely comprised of bacteria. Green macroalgae were important food sources for the gastropods; diatoms and mangrove biomass contributed to the nutrition of the crabs, although their contributions were smaller.

  15. Strengthening Mechanisms and Their Relative Contributions to the Yield Strength of Microalloyed Steels

    NASA Astrophysics Data System (ADS)

    Lu, Junfang; Omotoso, Oladipo; Wiskel, J. Barry; Ivey, Douglas G.; Henein, Hani

    2012-09-01

    Microalloyed steels are used widely in oil and gas pipelines. They are a class of high-strength, low-carbon steels that contain small additions (in amounts less than 0.1 wt pct) of Nb, Ti, and/or V. The steels may contain other alloying elements, such as Mo, in amounts exceeding 0.1 wt pct. Precipitation in these steels can be controlled through thermomechanical-controlled processing, leading to precipitates with sizes that range from several microns to a few nanometers. Microalloyed steels have good strength, good toughness, and excellent weldability, which are attributed in part to the presence of the nanosized carbide and carbonitride precipitates. Because of their fine sizes, wide particle size distribution, and low volume fractions, conventional microscopic methods are not satisfactory for quantifying these precipitates. Matrix dissolution is a promising alternative to extract the precipitates for quantification. Relatively large volumes of material can be analyzed so that statistically significant quantities of precipitates of different sizes are collected. In this article, the microstructure features of a series of microalloyed steels (X70, X80, and X100) as well as a Grade 100 steel are characterized using optical microscopy (OM) and scanning electron microscopy (SEM). A chemical dissolution technique is used to extract the precipitates from the steels. Transmission electron microscopy (TEM) and X-ray diffraction (XRD) are combined to analyze the chemical composition of these precipitates. Rietveld refinement of the XRD patterns is used to quantify fully the relative amounts of these precipitates. The size distribution of the nanosized precipitates is quantified using dark-field imaging (DF) in the TEM. The effects of microalloying content, finish rolling temperature (FRT), and coiling temperature (CT)/interrupted cooling temperature (ICT) on the grain size and the amount of nanoprecipitation are discussed. Individual strengthening contributions from grain size effects, solid-solution strengthening, and precipitation strengthening are quantified to understand fully the strengthening mechanisms for these steels.

  16. Intra-generational Redistribution under Public Pension Planning Based on Generation-based Funding Scheme

    NASA Astrophysics Data System (ADS)

    Banjo, Daisuke; Tamura, Hiroyuki; Murata, Tadahiko

    In this paper, we propose a method of determining the pension in the generation-based funding scheme. In this proposal, we include two types of pensions in the scheme. One is the payment-amount related pension and the other is the payment-frequency related pension. We set the ratio of the total amount of payment-amount related pension to the total amount of both pensions, and simulate income gaps and the relationship between contributions and benefits for each individual when the proposed method is applied.

  17. Regional economic contributions of the forest-based industries in the south

    Treesearch

    P.B. Aruna; Frederick Cubbage; Karen Abt; Clair Redmond

    1997-01-01

    Forest-based industries (including forestry) make substantial direct contributions to the economy of the South, as well as contributing to pleasant living conditions and environmental protection. As of 1992, about 633,000 persons were employed in forest-based industries, comprising 1.5 percent of all southern employment. Total wages amounted to $15 billion in 1990, or...

  18. 26 CFR 1.404(a)-7 - Pension and annuity plans; contributions in excess of limitations under section 404(a)(1...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... years 15,000 Taxable Year Ending Dec. 31, 1956 Amount of contributions paid in year $10,000 Carried over...)(D). When contributions paid by an employer in a taxable year to or under a pension or annuity plan... contributions are carried over and are deductible in succeeding taxable years of the employer in order of time...

  19. Removal of cypermethrin with seaweed Gracilaria lemaneiformis

    NASA Astrophysics Data System (ADS)

    Wang, Zhaohui; Yue, Wenjie

    2015-10-01

    The removal of cypermethrin with a red macroalga, Gracilaria lemaneiformis, was studied under laboratory conditions. Results showed that the residue contents with G. lemaneiformis were significantly lower than those corresponding groups without the algal thalli after 96 h treatment. The removal rates decreased with increasing concentrations, which were about 50% without G. lemaneiformis after 96 h exposure, and increased to 89%, 73%, and 66% in flasks with G. lemaneiformis at the concentrations of 10, 100, and 1000 µg L-1, respectively. The amount of biosorption (absorption and adsorption) by G. lemaneiformis increased with the increasing concentration and exposure time. Adsorption was the main process for the removal by G. lemaneiformis, which accounted for 75%-97% of the total biosorption. However, biosorption only contributed 0.5%-19.3% to the total losses of cypermethrin, which was more efficient under the low concentration. Natural losses contributed the largest portion of losses, which was over 65% in all treatments during the experiment. The unknown pathway of removal, which might be the bio-decomposed by microorganisms attaching the algal thalli, also contributed a lot to the total removal. The results suggested that cultivation of G. lemaneiformis could significantly remove cypermethrin, especially at low concentrations, and large-scale cultivation of G. lemaneiformis has considerable potential of biorestoration of eutrophic and cypermethrin-polluted coastal sea areas.

  20. Geoneutrinos and Heat Production in the Earth: Constraints and Implications

    ScienceCinema

    McDonough, Bill

    2017-12-29

    Recent results from antineutrino (geoneutrino) studies at KamLAND are coincident with geochemical models of Th and U in the Earth.  KamLAND and Borexino detectors are on line, thus uncertainties in counting statistics will be reduced as data are accumulated.  The SNO+ detector, situated in the middle of the North American plate will come on line in ~3 yrs and will be best suited to yield a precise estimate of the continental contribution to the Earth’s Th & U budget.  The distribution of heat producing elements in the Earth drives convection and plate tectonics.  Geochemical models posit that ~40% of the heat producing elements are in the continental crust, with the remainder in the mantle.  Although models of core formation allow for the incorporation of heat producing elements, the core contribution of radiogenic heating is considered to be negligible.  Most parameterized convection models for the Earth require significant amounts of radiogenic heating of the Earth, a factor of two greater than geochemical models predict.  The initial KamLAND results challenge these geophysical models and support geochemical models calling for a significant contribution from secular cooling of the mantle.

  1. Aerosol cloud interactions in southeast Pacific stratocumulus: satellite observations, in situ data and regional modeling

    NASA Astrophysics Data System (ADS)

    George, Rhea

    The influence of anthropogenic aerosols on cloud radiative properties in the persistent southeast Pacific stratocumulus deck is investigated using MODIS satellite observations, in situ data from the VAMOS Ocean-Cloud-Atmosphere-Land Study Regional Experiment (VOCALS-REx), and WRF-Chem, a regional model with interactive chemistry and aerosols. An albedo proxy is derived based on the fractional coverage of low cloud (a macrophysical field) and the cloud albedo, with the latter broken down into contributions from microphysics (cloud droplet concentration, Nd and macrophysics (liquid water path). Albedo variability is dominated by low cloud fraction variability, except within 10-15° of the South American coast, where cloud albedo variability contributes significantly. Covariance between cloud fraction and cloud albedo also contributes significantly to the variance in albedo, which highlights how complex and inseparable the factors controlling albedo are. N d variability contributes only weakly, which emphasizes that attributing albedo variability to the indirect effects of aerosols against the backdrop of natural meteorological variability is extremely challenging. Specific cases of aerosol changes can have strong impacts on albedo. We identify a pathway for periodic anthropogenic aerosol transport to the unpolluted marine stratocumulus >1000 km offshore, which strongly enhances Nd and albedo in zonally-elongated 'hook'-shaped arc. Hook development occurs with Nd increasing to polluted levels over the remote ocean primarily due to entrainment of a large number of small aerosols from the free troposphere that contribute a relatively small amount of aerosol mass to the marine boundary layer. Strong, deep offshore flow needed to transport continental aerosols to the remote ocean is favored by a trough approaching the South American coast and a southeastward shift of the climatological subtropical high pressure system. DMS significantly influences the aerosol number and size distributions, but does not cause hooks. The Twomey effect contributes 50-80% of the total aerosol indirect effect (AIE) both near sources and offshore during hook events. Meteorological variability between simulations can swamp the signal of AIEs, particularly due to the binary model cloud fraction field and distinguishing AIE requires determination of appropriate spatial and temporal averaging scales over which AIE is significant above this noise.

  2. Dissection of additive, dominance, and imprinting effects for production and reproduction traits in Holstein cattle.

    PubMed

    Jiang, Jicai; Shen, Botong; O'Connell, Jeffrey R; VanRaden, Paul M; Cole, John B; Ma, Li

    2017-05-30

    Although genome-wide association and genomic selection studies have primarily focused on additive effects, dominance and imprinting effects play an important role in mammalian biology and development. The degree to which these non-additive genetic effects contribute to phenotypic variation and whether QTL acting in a non-additive manner can be detected in genetic association studies remain controversial. To empirically answer these questions, we analyzed a large cattle dataset that consisted of 42,701 genotyped Holstein cows with genotyped parents and phenotypic records for eight production and reproduction traits. SNP genotypes were phased in pedigree to determine the parent-of-origin of alleles, and a three-component GREML was applied to obtain variance decomposition for additive, dominance, and imprinting effects. The results showed a significant non-zero contribution from dominance to production traits but not to reproduction traits. Imprinting effects significantly contributed to both production and reproduction traits. Interestingly, imprinting effects contributed more to reproduction traits than to production traits. Using GWAS and imputation-based fine-mapping analyses, we identified and validated a dominance association signal with milk yield near RUNX2, a candidate gene that has been associated with milk production in mice. When adding non-additive effects into the prediction models, however, we observed little or no increase in prediction accuracy for the eight traits analyzed. Collectively, our results suggested that non-additive effects contributed a non-negligible amount (more for reproduction traits) to the total genetic variance of complex traits in cattle, and detection of QTLs with non-additive effect is possible in GWAS using a large dataset.

  3. Disturbance of gut satiety peptide in purging disorder.

    PubMed

    Keel, Pamela K; Eckel, Lisa A; Hildebrandt, Britny A; Haedt-Matt, Alissa A; Appelbaum, Jonathan; Jimerson, David C

    2018-01-01

    Little is known about biological factors that contribute to purging after normal amounts of food-the central feature of purging disorder (PD). This study comes from a series of nested studies examining ingestive behaviors in bulimic syndromes and specifically evaluated the satiety peptide YY (PYY) and the hunger peptide ghrelin in women with PD (n = 25), bulimia nervosa-purging (BNp) (n = 26), and controls (n = 26). Based on distinct subjective responses to a fixed meal in PD (Keel, Wolfe, Liddle, DeYoung, & Jimerson, ), we tested whether postprandial PYY response was significantly greater and ghrelin levels significantly lower in women with PD compared to controls and women with BNp. Participants completed structured clinical interviews, self-report questionnaires, and laboratory assessments of gut peptide and subjective responses to a fixed meal. Women with PD demonstrated a significantly greater postprandial PYY response compared to women with BNp and controls, who did not differ significantly. PD women also endorsed significantly greater gastrointestinal distress, and PYY predicted gastrointestinal intestinal distress. Ghrelin levels were significantly greater in PD and BNp compared to controls, but did not differ significantly between eating disorders. Women with BNp endorsed significantly greater postprandial hunger, and ghrelin predicted hunger. PD is associated with a unique disturbance in PYY response. Findings contribute to growing evidence of physiological distinctions between PD and BNp. Future research should examine whether these distinctions account for differences in clinical presentation as this could inform the development of specific interventions for patients with PD. © 2017 Wiley Periodicals, Inc.

  4. Wear and Tear of Tyres: A Stealthy Source of Microplastics in the Environment

    PubMed Central

    Kole, Pieter Jan; Löhr, Ansje J.; Van Belleghem, Frank G. A. J.; Ragas, Ad M. J.

    2017-01-01

    Wear and tear from tyres significantly contributes to the flow of (micro-)plastics into the environment. This paper compiles the fragmented knowledge on tyre wear and tear characteristics, amounts of particles emitted, pathways in the environment, and the possible effects on humans. The estimated per capita emission ranges from 0.23 to 4.7 kg/year, with a global average of 0.81 kg/year. The emissions from car tyres (100%) are substantially higher than those of other sources of microplastics, e.g., airplane tyres (2%), artificial turf (12–50%), brake wear (8%) and road markings (5%). Emissions and pathways depend on local factors like road type or sewage systems. The relative contribution of tyre wear and tear to the total global amount of plastics ending up in our oceans is estimated to be 5–10%. In air, 3–7% of the particulate matter (PM2.5) is estimated to consist of tyre wear and tear, indicating that it may contribute to the global health burden of air pollution which has been projected by the World Health Organization (WHO) at 3 million deaths in 2012. The wear and tear also enters our food chain, but further research is needed to assess human health risks. It is concluded here that tyre wear and tear is a stealthy source of microplastics in our environment, which can only be addressed effectively if awareness increases, knowledge gaps on quantities and effects are being closed, and creative technical solutions are being sought. This requires a global effort from all stakeholders; consumers, regulators, industry and researchers alike. PMID:29053641

  5. Wear and Tear of Tyres: A Stealthy Source of Microplastics in the Environment.

    PubMed

    Kole, Pieter Jan; Löhr, Ansje J; Van Belleghem, Frank G A J; Ragas, Ad M J

    2017-10-20

    Wear and tear from tyres significantly contributes to the flow of (micro-)plastics into the environment. This paper compiles the fragmented knowledge on tyre wear and tear characteristics, amounts of particles emitted, pathways in the environment, and the possible effects on humans. The estimated per capita emission ranges from 0.23 to 4.7 kg/year, with a global average of 0.81 kg/year. The emissions from car tyres (100%) are substantially higher than those of other sources of microplastics, e.g., airplane tyres (2%), artificial turf (12-50%), brake wear (8%) and road markings (5%). Emissions and pathways depend on local factors like road type or sewage systems. The relative contribution of tyre wear and tear to the total global amount of plastics ending up in our oceans is estimated to be 5-10%. In air, 3-7% of the particulate matter (PM 2.5 ) is estimated to consist of tyre wear and tear, indicating that it may contribute to the global health burden of air pollution which has been projected by the World Health Organization (WHO) at 3 million deaths in 2012. The wear and tear also enters our food chain, but further research is needed to assess human health risks. It is concluded here that tyre wear and tear is a stealthy source of microplastics in our environment, which can only be addressed effectively if awareness increases, knowledge gaps on quantities and effects are being closed, and creative technical solutions are being sought. This requires a global effort from all stakeholders; consumers, regulators, industry and researchers alike.

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shen, Bo; Lu, Hongyou; Price, Lynn K.

    In the U.S., energy consumption by steam and process heat combined accounts for over 50% of the total energy use from industrial systems (see Figure 1). The use of boilers, process heaters, and furnaces for generating steam and heat in industrial facilities, commercial settings, and institutions consumes significant amounts of energy and is one of major sources of hazardous air pollutants, which contribute significantly to local pollution and global climate change. To address the energy and environmental challenges caused by boiler systems in the U.S., the country has taken a series of actions to reduce emissions from industrial, commercial andmore » institutional boilers, improve the efficiency of steam systems, replace coal with cleaner energy resources, and promote the wider use of combined heat and power (CHP).« less

  7. Physiological basis of dietary prevention of perimenopausal disorders in the context of dietary habits associated with the consumption of water and beverages by women aged 45-65

    PubMed Central

    Remiszewska, Zuzanna

    2014-01-01

    Introduction This study aimed to evaluate the amount of water and type of beverages consumed by women of perimenopausal age against a background of dietary prevention of perimenopausal disorders. Material and methods This study was conducted in autumn 2012, in Wielkopolska Province (Poland), on 100 women aged from 45 to 65 years, employed as office workers. Information on the diet, beverages consumption and anthropometric data were collected. Results Analysis of the nutritional status of the surveyed women showed that over 50% of them had excess body weight. Analysis of the survey results indicated that the amount of water in the diet of the examined women was appropriate, although the type of drinks consumed was inadequate. The women consumed too much coffee and tea, and simultaneously had a low intake of potable water. More than a half of the surveyed women sweetened coffee and tea. Women with excess body weight did so statistically significantly quite often, and they also used larger amounts of sugar for sweetening. Nearly 60% of the surveyed women added milk, or less frequently cream, to coffee. Milk was statistically significantly more frequently chosen by women with normal body weight, and cream by women with excess body weight. There was a positive correlation between body mass index and the energy value of the consumed fluids. Conclusions The dietary irregularities identified in this study may intensify perimenopausal symptoms and contribute to the development of diet-related chronic diseases. Taking into account the observed irregularities, it seems appropriate to provide perimenopausal women with nutrition education and diet correction, including the amount and type of fluids consumed. PMID:26327836

  8. Measurement of funny current (I(f)) channel mRNA in human atrial tissue: correlation with left atrial filling pressure and atrial fibrillation.

    PubMed

    Lai, L P; Su, M J; Lin, J L; Tsai, C H; Lin, F Y; Chen, Y S; Hwang, J J; Huang, S K; Tseng, Y Z; Lien, W P

    1999-07-01

    The funny current (I(f)) contributes to phase IV spontaneous depolarization in cardiac pacemaker tissue. Enhanced I(f) activity in myocardial tissue may lead to increased automaticity and therefore tachyarrhythmia. We measured the amount of I(f) activity in the messenger ribonucleic acid (mRNA) in human atrial tissue and correlated the mRNA amount to left atrial filling pressure and atrial fibrillation (AF). A total of 34 patients undergoing open heart surgery were included (15 men and 19 women, aged 55+/-10 years). Atrial tissue was obtained from the right atrial free wall, the right atrial appendage, the left atrial free wall, and the left atrial appendage, respectively. The mRNA amount of the I(f) channel was measured by reverse transcription polymerase chain reaction and was normalized to the mRNA levels of glyceraldehyde 3-phosphate dehydrogenase. We found that the I(f) channel mRNA was present at all the atrial sampling sites. A higher left atrial filling pressure, an indicator of congestive heart failure, was associated with a higher I(f) mRNA level (r2 = 0.446, P < 0.01 by linear regression). We also found that the mRNA amount was significantly higher in patients with AF than in patients without AF (1.68+/-0.49 vs 1.27+/-0.43; P < 0.05). Age, sex, right atrial filling pressure, left atrial dimension, and left ventricular ejection fraction had no significant effect on the mRNA level. The mRNA of the I(f) channel is present in the free-wall area and appendage area from both atria. Increased left atrial filling pressure and clinical AF are associated with increased I(f) mRNA level.

  9. Morphological characterization of pollens from three Apiaceae species and their ingestion by twelve-spotted lady beetle (Coleoptera: Coccinellidae).

    PubMed

    D'Ávila, V A; Aguiar-Menezes, E L; Gonçalves-Esteves, V; Mendonça, C B F; Pereira, R N; Santos, T M

    2016-04-19

    Larvae and adults of certain species of predator lady beetles feed on pollen, guaranteeing their survival, and at times, reproduction in the absence of preferred prey. Palynology, therefore, may contribute in the investigation of botanical families visited by these predators in order to obtain this floral resource. There are records of the visitation of Apiaceae flowers by Coleomegilla maculata DeGeer, 1775 (Coleoptera, Coccinellidae), but not the ingestion of their pollen grains by this lady beetle. The external morphology of pollen grains of three Apiaceae aromatic species (Anethum graveolens L., Coriandrum sativum L., Foeniculum vulgare Mill.) was characterized, and it was evaluated the ingestion of these pollens by fourth instar larvae and adults of C. maculata upon confinement along with flowers of these Apiaceae for 24 and 48 hours. The pollen grains of those species presented similar external morphology. In the two times of exposure, the larvae ingested the same amount of pollen from the three Apiaceae species, and the amount of C. sativum pollen ingested was the same between larvae and adults. The amount of A. graveolens pollen grains ingested by the adults was significantly greater than the pollens of C. sativum and F. vulgare, in 24 hours, with the opposite occurring in 48 hours. In the first 24 hours, the adults ingested more A. graveolens pollen than the larvae, with the opposite occurring with F. vulgare. There was no significant difference in the amount of Apiaceae pollen ingested between larvae and adults in 48 hours. The results suggest that the pollen-eating habits of certain aphidophagous lady beetles may be crucial in their preservation within agro-ecosystems.

  10. 26 CFR 1.402A-1 - Designated Roth Accounts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... relationship between the accounting for designated Roth contributions as investment in the contract for... includible in gross income as an amount allocable to investment in the contract is determined under section... contract and the portion not includible in gross income as an amount allocable to investment in the...

  11. The dynamics of nitrogen derived from a chemical nitrogen fertilizer with treated swine slurry in paddy soil-plant systems

    PubMed Central

    Lee, Joonhee

    2017-01-01

    A well-managed chemical nitrogen (N) fertilization practice combined with treated swine slurry (TSS) is necessary to improve sustainability and N use efficiency in rice farming. However, little is known about the fate of N derived from chemical N fertilizer with and without TSS in paddy soil-plant systems. The objectives of this study were (1) to estimate the contribution of applied N fertilizer to N turnover in rice paddy soil with different N fertilization practices that were manipulated by the quantity of treated swine slurry and chemical N fertilizer (i.e., HTSS+LAS, a high amount of TSS with a low amount of ammonium sulfate; LTSS+HAS, a low amount of TSS with a high amount of ammonium sulfate; AS, ammonium sulfate with phosphorus and potassium; C, the control) and (2) to compare the rice response to applied N derived from each N fertilization practice. Rice biomass yield, 15N recovery in both rice grain and stems, soil total N (TN), soil inorganic N, and soil 15N recovery were analyzed. Similar amounts of 15N uptake by rice in the TSS+AS plots were obtained, indicating that the effects of the different quantities of TSS on chemical fertilizer N recovery in rice during the experimental period were not significant. The soil 15N recoveries of HTSS+LAS, LTSS+HAS, and AS in each soil layer were not significantly different. For the HTSS+LAS, LTSS+HAS and AS applications, total 15N recoveries were 42%, 43% and 54%, respectively. Because the effects of reducing the use of chemical N fertilizer were attributed to enhancing soil quality and cost-effectiveness, HTSS+LAS could be an appropriate N fertilization practice for improving the long-term sustainability of paddy soil-plant systems. However, N losses, especially through the coupled nitrification-denitrification process, can diminish the benefits that HTSS+LAS offers. PMID:28339491

  12. The dynamics of nitrogen derived from a chemical nitrogen fertilizer with treated swine slurry in paddy soil-plant systems.

    PubMed

    Lee, Joonhee; Choi, Hong L

    2017-01-01

    A well-managed chemical nitrogen (N) fertilization practice combined with treated swine slurry (TSS) is necessary to improve sustainability and N use efficiency in rice farming. However, little is known about the fate of N derived from chemical N fertilizer with and without TSS in paddy soil-plant systems. The objectives of this study were (1) to estimate the contribution of applied N fertilizer to N turnover in rice paddy soil with different N fertilization practices that were manipulated by the quantity of treated swine slurry and chemical N fertilizer (i.e., HTSS+LAS, a high amount of TSS with a low amount of ammonium sulfate; LTSS+HAS, a low amount of TSS with a high amount of ammonium sulfate; AS, ammonium sulfate with phosphorus and potassium; C, the control) and (2) to compare the rice response to applied N derived from each N fertilization practice. Rice biomass yield, 15N recovery in both rice grain and stems, soil total N (TN), soil inorganic N, and soil 15N recovery were analyzed. Similar amounts of 15N uptake by rice in the TSS+AS plots were obtained, indicating that the effects of the different quantities of TSS on chemical fertilizer N recovery in rice during the experimental period were not significant. The soil 15N recoveries of HTSS+LAS, LTSS+HAS, and AS in each soil layer were not significantly different. For the HTSS+LAS, LTSS+HAS and AS applications, total 15N recoveries were 42%, 43% and 54%, respectively. Because the effects of reducing the use of chemical N fertilizer were attributed to enhancing soil quality and cost-effectiveness, HTSS+LAS could be an appropriate N fertilization practice for improving the long-term sustainability of paddy soil-plant systems. However, N losses, especially through the coupled nitrification-denitrification process, can diminish the benefits that HTSS+LAS offers.

  13. Expanding the psychosocial work environment: workplace norms and work-family conflict as correlates of stress and health.

    PubMed

    Hammer, Tove Helland; Saksvik, Per Øystein; Nytrø, Kjell; Torvatn, Hans; Bayazit, Mahmut

    2004-01-01

    This study examined the contributions of organizational level norms about work requirements and social relations, and work-family conflict, to job stress and subjective health symptoms, controlling for Karasek's job demand-control-support model of the psychosocial work environment, in a sample of 1,346 employees from 56 firms in the Norwegian food and beverage industry. Hierarchical linear modeling analyses showed that organizational norms governing work performance and social relations, and work-to-family and family-to-work conflict, explained significant amounts of variance for job stress. The cross-level interaction between work performance norms and work-to-family conflict was also significantly related to job stress. Work-to-family conflict was significantly related to health symptoms, but family-to-work conflict and organizational norms were not.

  14. Spores of most common airborne fungi reveal no ice nucleation activity

    NASA Astrophysics Data System (ADS)

    Pummer, B. G.; Atanasova, L.; Bauer, H.; Bernardi, J.; Druzhinina, I. S.; Grothe, H.

    2013-06-01

    Fungal spores are ubiquitous biological aerosols, which are considered to show ice nucleation (IN) activity. In this study the respective IN activity was tested in oil emulsion in the immersion freezing mode. The focus was laid on species of economical, ecological or sanitary significance. For the first time, not only common moulds, but also edible mushrooms (Basidiomycota, Agaricomycetes) were investigated, as they contribute massively to the total amount of fungal spores in the atmosphere. Only Fusarium avenaceum showed freezing events at low subzero-temperatures, while the other investigated fungal spores showed no significant IN activity. Furthermore, we selected a set of fungal strains from different sites and exposed them to occasional freezing stress during cultivation. Although the total protein expression was altered by this treatment, it had no significant impact on the IN activity.

  15. Ferret mothers provide more anogenital licking to male offspring: possible contribution to psychosexual differentiation.

    PubMed

    Baum, M J; Bressler, S C; Daum, M C; Veiga, C A; McNamee, C S

    1996-08-01

    European ferret (Mustela putorius furo) mothers displayed significantly higher levels of anogenital licking (AGL) towards male as opposed to female kits in tests given on postpartum (P) days 6, 12, and 15. In these tests the entire litter was removed from the nestbox for 10 min, whereupon individual male and female kits were reintroduced to the mother in a counterbalanced order. In a second study an analysis of videotapes, sampled over the 24 h of several days, showed that mothers provided significantly more AGL to males than to females on P15, with a similar trend being observed on P1 and P8. This difference was no longer present on P22. In neither experiment was any sex difference observed in the amount of maternal licking of other (nonanogenital) body parts or in maternal carrying behavior received by kits. These results are comparable to those previously published for rat and gerbil, and further emphasize the possible contribution of sex differences in maternal stimulation, especially AGL, to the development of sexually dimorphic features of brain and behavioral development in different mammalian orders.

  16. Forensic Features of Clothing-Related Deaths: Historical and Cultural Aspects.

    PubMed

    Byard, Roger W

    2017-12-01

    Clothing may both cause death and contribute to ongoing lethal mechanisms by a variety of quite disparate mechanisms. The manner of death may be accidental, suicidal, or homicidal. Accidental deaths include burning from clothing catching on fire, strangulation from clothing tangling in vehicle wheels or exposed machinery, and drowning. Entanglement of clothing in machinery may also result in significant injuries, which are not uncommon in farming communities. Excessive clothing, or its absence, may significantly alter body temperature, and hanging from clothing is a feature in the young or in mentally or physically handicapped adults, or in adults who are intoxicated with alcohol or drugs. In previous years, potentially lethal amounts of arsenic were present in clothing and accessories from dyes. Clothing may also be used to form nooses or to pad ropes in suicides and may be used in cases of strangulation, suffocation, or choking in homicides. The contribution of clothing to mortality has changed over the years with changes in fashions and in manufacturing techniques. Geographical differences in clothing-related deaths persist because of variable social and cultural practices and legislative frameworks.

  17. Non-adiabatic pumping in an oscillating-piston model

    NASA Astrophysics Data System (ADS)

    Chuchem, Maya; Dittrich, Thomas; Cohen, Doron

    2012-05-01

    We consider the prototypical "piston pump" operating on a ring, where a circulating current is induced by means of an AC driving. This can be regarded as a generalized Fermi-Ulam model, incorporating a finite-height moving wall (piston) and non-trivial topology (ring). The amount of particles transported per cycle is determined by a layered structure of phase space. Each layer is characterized by a different drift velocity. We discuss the differences compared with the adiabatic and Boltzmann pictures, and highlight the significance of the "diabatic" contribution that might lead to a counter-stirring effect.

  18. Generation and Functional Evaluation of Designer Monoterpene Synthases.

    PubMed

    Srividya, N; Lange, I; Lange, B M

    2016-01-01

    Monoterpene synthases are highly versatile enzymes that catalyze the first committed step in the pathways toward terpenoids, the structurally most diverse class of plant natural products. Recent advancements in our understanding of the reaction mechanism have enabled engineering approaches to develop mutant monoterpene synthases that produce specific monoterpenes. In this chapter, we are describing protocols to introduce targeted mutations, express mutant enzyme catalysts in heterologous hosts, and assess their catalytic properties. Mutant monoterpene synthases have the potential to contribute significantly to synthetic biology efforts aimed at producing larger amounts of commercially attractive monoterpenes. © 2016 Elsevier Inc. All rights reserved.

  19. Towards a definition of the "practical" epileptogenic zone: a case of epilepsy with dual pathology.

    PubMed

    Chassagnon, Serge; Valenti, Maria Paola; Sabourdy, Cécile; Esposito, Philippe; Kehrli, Pierre; Arzimanoglou, Alexis; Ryvlin, Philippe; Kahane, Philippe; Hirsch, Edouard

    2006-08-01

    Presurgical evaluation for patients with drug-resistant epilepsy requires the definition of various zones that have a variable spatial relationship with the epileptogenic zone. All the available methods to directly measure the actual seizure-onset zone and to define "the minimum amount of cortical tissue that must be resected to produce seizure-freedom" have significant limitations. We report on the case of a patient with dual pathology (hippocampal sclerosis and a post-traumatic scar) and discuss the contribution of the various presurgical investigations that led to surgery and seizure-freedom.

  20. Industrial contributions of arsenic to the environment.

    PubMed Central

    Nelson, K W

    1977-01-01

    Arsenic is present in all copper, lead, and zinc sulfide ores and is carried along with those metals in the mining, milling and concentrating process. Separation, final concentration and refining of by-product arsenic as the trioxide is achieved at smelters. Arsenic is the essential consistent element of many compounds important and widely used in agriculture and wood preservation. Lesser amounts are used in metal alloys, glass-making, and feed additives. There is no significant recycling. Current levels of arsenic emissions to the atmosphere from smelters and power plants and ambient air concentrations are given as data of greatest environmental interest. PMID:908308

  1. Key drivers of precipitation isotopes in Windhoek, Namibia (2012-2016)

    NASA Astrophysics Data System (ADS)

    Kaseke, K. F.; Wang, L.; Wanke, H.

    2017-12-01

    Southern African climate is characterized by large variability with precipitation model estimates varying by as much as 70% during summer. This difference between model estimates is partly because most models associate precipitation over Southern Africa with moisture inputs from the Indian Ocean while excluding inputs from the Atlantic Ocean. However, growing evidence suggests that the Atlantic Ocean may also contribute significant amounts of moisture to the region. This four-year (2012-2016) study investigates the isotopic composition (δ18O, δ2H and δ17O) of event-scale precipitation events, the key drivers of isotope variations and the origins of precipitation experienced in Windhoek, Namibia. Results indicate large storm-to-storm isotopic variability δ18O (25‰), δ2H (180‰) and δ17O (13‰) over the study period. Univariate analysis showed significant correlations between event precipitation isotopes and local meteorological parameters; lifted condensation level, relative humidity (RH), precipitation amount, average wind speed, surface and air temperature (p < 0.05). The number of significant correlations between local meteorological parameters and monthly isotopes was much lower suggesting loss of information through data aggregation. Nonetheless, the most significant isotope driver at both event and monthly scales was RH, consistent with the semi-arid classification of the site. Multiple linear regression analysis suggested RH, precipitation amount and air temperature were the most significant local drivers of precipitation isotopes accounting for about 50% of the variation implying that about 50% could be attributed to source origins. HYSLPIT trajectories indicated that 78% of precipitation originated from the Indian Ocean while 21% originated from the Atlantic Ocean. Given that three of the four study years were droughts while two of the three drought years were El Niño related, our data also suggests that δ'17O-δ'18O could be a useful tool to differentiate local vs synoptic (El Niño) droughts.

  2. Nitrous oxide flux from landfill leachate-sawdust nitrogenous compost.

    PubMed

    Hui, C H; So, M K; Lee, C M; Chan, G Y S

    2003-09-01

    Composted nitrogenous waste has the potential to produce excessive amounts of nitrous oxide (N2O), a potent greenhouse gas that also contributes to stratospheric ozone depletion. In this laboratory study, sawdust was irrigated with varying amounts of landfill leachate with high NH4+-N content (3950 mg l(-1)). Physicochemical properties, including the amount of N2O produced, were monitored during the composting process over 28 days. A rapid decline in NH4+-N in the first 4 days and increasing NO3--N for 11 days was followed by lower but stabilized levels of available-N, even with repeated leachate irrigation. Less than 0.03% of the leachate-applied N was lost as N2O. Higher leachate applications as much as tripled N2O production, but this represented a lesser proportion overall of the total nitrogen. Addition of glucose to the composting process had no significant effect on N2O production. The derived sawdust-leachate compost supported healthy growth of Sesbania rostrata. It is concluded that compost can be produced from sawdust irrigated with landfill leachate without substantial emission of N2O, although excessive flux of N2O remains about high application rates over longer time periods.

  3. 20 CFR 345.105 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EMPLOYERS' CONTRIBUTIONS AND CONTRIBUTION REPORTS General Provisions and Definitions § 345.105 Definitions... from employers under this part. (b) Monthly compensation base. For the purposes of this part, the monthly compensation base (MCB) is the maximum monthly amount of compensation per employee that is subject...

  4. Systematic review: factors contributing to burnout in dentistry.

    PubMed

    Singh, P; Aulak, D S; Mangat, S S; Aulak, M S

    2016-01-01

    Dentists and dental students have been reported to be at high risk of burnout and risk factors have been identified. Despite research into burnout in dentists, only a few papers have identified significantly associated factors. To identify the most significant factors associated with burnout in dentists and dental students in published literature. We systematically searched MEDLINE, EMBASE and HMIC electronic databases to source literature on the factors associated with burnout in dentists. We critically appraised and themed papers using the Critical Appraisal Skills Programme to find the most significant factors. From 115 studies identified by the search string, we deemed 33 papers to be relevant for review. The most prevalent and significant factors associated with burnout were: younger age, male gender, student status, high job-strain/working hours, those enrolled in clinical degree programmes and certain personality types. However, only a limited amount of literature explored the directional relationship between these factors and burnout. This review identified several significant factors contributing to burnout in dentists and dental students. Further longitudinal and prospective studies are required to assess causation. Burnout should be considered a multifactorial phenomenon that can develop early in a dental career. Screening programmes and coping strategies might help to identify and prevent it. © The Author 2015. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. Understanding the Relative Contributions of Lower-Level Word Processes, Higher-Level Processes, and Working Memory to Reading Comprehension Performance in Proficient Adult Readers

    ERIC Educational Resources Information Center

    Hannon, Brenda

    2012-01-01

    Although a considerable amount of evidence has been amassed regarding the contributions of lower-level word processes, higher-level processes, and working memory to reading comprehension, little is known about the relationships among these sources of individual differences or their relative contributions to reading comprehension performance. This…

  6. 26 CFR 1.170-1 - Charitable, etc., contributions and gifts; allowance of deduction (before amendment by Tax Reform...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contribution is made in property other than money, the amount of the deduction is determined by the fair market... than money, the taxpayer shall state the kind of property contributed (for example, used clothing, paintings, securities) and shall state the method utilized in determining the fair market value of the...

  7. Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome.

    PubMed

    Velazquez, Ramon; Ash, Jessica A; Powers, Brian E; Kelley, Christy M; Strawderman, Myla; Luscher, Zoe I; Ginsberg, Stephen D; Mufson, Elliott J; Strupp, Barbara J

    2013-10-01

    In addition to intellectual disability, individuals with Down syndrome (DS) exhibit dementia by the third or fourth decade of life, due to the early onset of neuropathological changes typical of Alzheimer's disease (AD). Deficient ontogenetic neurogenesis contributes to the brain hypoplasia and hypocellularity evident in fetuses and children with DS. A murine model of DS and AD (the Ts65Dn mouse) exhibits key features of these disorders, notably deficient ontogenetic neurogenesis, degeneration of basal forebrain cholinergic neurons (BFCNs), and cognitive deficits. Adult hippocampal (HP) neurogenesis is also deficient in Ts65Dn mice and may contribute to the observed cognitive dysfunction. Herein, we demonstrate that supplementing the maternal diet with additional choline (approximately 4.5 times the amount in normal rodent chow) dramatically improved the performance of the adult trisomic offspring in a radial arm water maze task. Ts65Dn offspring of choline-supplemented dams performed significantly better than unsupplemented Ts65Dn mice. Furthermore, adult hippocampal neurogenesis was partially normalized in the maternal choline supplemented (MCS) trisomic offspring relative to their unsupplemented counterparts. A significant correlation was observed between adult hippocampal neurogenesis and performance in the water maze, suggesting that the increased neurogenesis seen in the supplemented trisomic mice contributed functionally to their improved spatial cognition. These findings suggest that supplementing the maternal diet with additional choline has significant translational potential for DS. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

    PubMed Central

    Velazquez, Ramon; Ash, Jessica A.; Powers, Brian E.; Kelley, Christy M.; Strawderman, Myla; Luscher, Zoe I.; Ginsberg, Stephen D.; Mufson, Elliott J.; Strupp, Barbara J.

    2014-01-01

    In addition to intellectual disability, individuals with Down syndrome (DS) exhibit dementia by the third or fourth decade of life, due to the early onset of neuropathological changes typical of Alzheimer’s disease (AD). Deficient ontogenetic neurogenesis contributes to the brain hypoplasia and hypocellularity evident in fetuses and children with DS. A murine model of DS and AD (the Ts65Dn mouse) exhibits key features of these disorders, notably deficient ontogenetic neurogenesis, degeneration of basal forebrain cholinergic neurons (BFCNs), and cognitive deficits. Adult hippocampal (HP) neurogenesis is also deficient in Ts65Dn mice and may contribute to the observed cognitive dysfunction. Herein, we demonstrate that supplementing the maternal diet with additional choline (approximately 4.5 times the amount in normal rodent chow) dramatically improved the performance of the adult trisomic offspring in a radial arm water maze task. Ts65Dn offspring of choline-supplemented dams performed significantly better than unsupplemented Ts65Dn mice. Furthermore, adult hippocampal neurogenesis was partially normalized in the maternal choline supplemented (MCS) trisomic offspring relative to their unsupplemented counterparts. A significant correlation was observed between adult hippocampal neurogenesis and performance in the water maze, suggesting that the increased neurogenesis seen in the supplemented trisomic mice contributed functionally to their improved spatial cognition. These findings suggest that supplementing the maternal diet with additional choline has significant translational potential for DS. PMID:23643842

  9. Assessing the Utility of Hydrogen, Carbon and Nitrogen Stable Isotopes in Estimating Consumer Allochthony in Two Shallow Eutrophic Lakes.

    PubMed

    Syväranta, Jari; Scharnweber, Kristin; Brauns, Mario; Hilt, Sabine; Mehner, Thomas

    2016-01-01

    Hydrogen stable isotopes (δ2H) have recently been used to complement δ13C and δ15N in food web studies due to their potentially greater power to separate sources of organic matter in aquatic food webs. However, uncertainties remain regarding the use of δ2H, since little is known about the potential variation in the amount of exchangeable hydrogen (Hex) among common sample materials or the patterns of δ2H when entire food webs are considered. We assessed differences in Hex among the typical sample materials in freshwater studies and used δ2H, δ13C and δ15N to compare their effectiveness in tracing allochthonous matter in food webs of two small temperate lakes. Our results showed higher average amounts of Hex in animal tissues (27% in fish and macroinvertebrates, 19% in zooplankton) compared to most plant material (15% in terrestrial plants and 8% in seston/periphyton), with the exception of aquatic vascular plants (23%, referred to as macrophytes). The amount of Hex correlated strongly with sample lipid content (inferred from C:N ratios) in fish and zooplankton samples. Overall, the three isotopes provided good separation of sources (seston, periphyton, macrophytes and allochthonous organic matter), particularly the δ2H followed by δ13C. Aquatic macrophytes revealed unexpectedly high δ2H values, having more elevated δ2H values than terrestrial organic matter with direct implications for estimating consumer allochthony. Organic matter from macrophytes significantly contributed to the food webs in both lakes highlighting the need to include macrophytes as a potential source when using stable isotopes to estimate trophic structures and contributions from allochthonous sources.

  10. Assessing the Utility of Hydrogen, Carbon and Nitrogen Stable Isotopes in Estimating Consumer Allochthony in Two Shallow Eutrophic Lakes

    PubMed Central

    Syväranta, Jari; Scharnweber, Kristin; Brauns, Mario; Hilt, Sabine; Mehner, Thomas

    2016-01-01

    Hydrogen stable isotopes (δ2H) have recently been used to complement δ13C and δ15N in food web studies due to their potentially greater power to separate sources of organic matter in aquatic food webs. However, uncertainties remain regarding the use of δ2H, since little is known about the potential variation in the amount of exchangeable hydrogen (Hex) among common sample materials or the patterns of δ2H when entire food webs are considered. We assessed differences in Hex among the typical sample materials in freshwater studies and used δ2H, δ13C and δ15N to compare their effectiveness in tracing allochthonous matter in food webs of two small temperate lakes. Our results showed higher average amounts of Hex in animal tissues (27% in fish and macroinvertebrates, 19% in zooplankton) compared to most plant material (15% in terrestrial plants and 8% in seston/periphyton), with the exception of aquatic vascular plants (23%, referred to as macrophytes). The amount of Hex correlated strongly with sample lipid content (inferred from C:N ratios) in fish and zooplankton samples. Overall, the three isotopes provided good separation of sources (seston, periphyton, macrophytes and allochthonous organic matter), particularly the δ2H followed by δ13C. Aquatic macrophytes revealed unexpectedly high δ2H values, having more elevated δ2H values than terrestrial organic matter with direct implications for estimating consumer allochthony. Organic matter from macrophytes significantly contributed to the food webs in both lakes highlighting the need to include macrophytes as a potential source when using stable isotopes to estimate trophic structures and contributions from allochthonous sources. PMID:27167517

  11. Urinary excretion of platinum, arsenic and selenium of cancer patients from the Antofagasta region in Chile treated with platinum-based drugs

    PubMed Central

    2012-01-01

    Background Arsenic exposure increases the risk of non-cancerous and cancerous diseases. In the Antofagasta region in Chile, an established relationship exists between arsenic exposure and the risk of cancer of the bladder, lung and skin. Platinum-based drugs are first-line treatments, and many works recognise selenium as a cancer-fighting nutrient. We characterised the short-term urinary excretion amounts of arsenic, selenium and platinum in 24-h urine samples from patients with lung cancer and those with cancer other than lung treated with cisplatin or/and carboplatin. As - Se - Pt inter-element relationships were also investigated. Results The amounts of platinum excreted in urine were not significantly different between patients with lung cancer and those with other cancers treated with cisplatin, despite the significant variation in platinum amounts supplied from platinum-based drugs. In general, the analytical amounts of excreted selenium were greater than those for arsenic, which could imply that platinum favours the excretion of selenium. For other types of cancers treated with drugs without platinum, excretion of selenium was also greater than that of arsenic, suggesting an antagonist selenium-anti-cancer drug relationship. Conclusions Regards the baseline status of patients, the analytical amounts of excreted Se is greater than those for As, particularly, for cisplatin chemotherapy. This finding could imply that for over the As displacement Pt favours the excretion of Se. The analytical amounts of excreted Se were greater than those for As, either with and without Pt-containing drugs, suggesting an antagonist Se-anti-cancer drug relationship. However, it seemed that differences existed between As - Se - Pt inter-element associations in patients treated for lung cancer in comparison with those treated for cancer other than lung. Therefore, knowledge obtained in this work, can contribute to understanding the arsenic cancer mechanism and the As - Se - Pt inter-element association for lung cancer and other types of cancer, which in some cases respond at a linear mathematical model. PMID:22546077

  12. Quantifying household waste of fresh fruit and vegetables in the EU.

    PubMed

    De Laurentiis, Valeria; Corrado, Sara; Sala, Serenella

    2018-04-11

    According to national studies conducted in EU countries, fresh fruit and vegetables contribute to almost 50% of the food waste generated by households. This study presents an estimation of this waste flow, differentiating between unavoidable and avoidable waste. The calculation of these two flows serves different purposes. The first (21.1 kg per person per year) provides a measure of the amount of household waste intrinsically linked to the consumption of fresh fruit and vegetables, and which would still be generated even in a zero-avoidable waste future scenario. The second (14.2 kg per person per year) is a quantity that could be reduced/minimised by applying targeted prevention strategies. The unavoidable waste was assessed at product level, by considering the inedible fraction and the purchased amounts of the fifty-one most consumed fruits and vegetables in Europe. The avoidable waste was estimated at commodity group level, based on the results of national studies conducted in six EU member states. Significant differences in the amounts of avoidable and unavoidable waste generated were found across countries, due to different levels of wasteful behaviours (linked to cultural and economic factors) and different consumption patterns (influencing the amount of unavoidable waste generated). The results of this study have implications for policies both on the prevention and the management of household food waste. Copyright © 2018 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  13. Episodic memory and appetite regulation in humans.

    PubMed

    Brunstrom, Jeffrey M; Burn, Jeremy F; Sell, Nicola R; Collingwood, Jane M; Rogers, Peter J; Wilkinson, Laura L; Hinton, Elanor C; Maynard, Olivia M; Ferriday, Danielle

    2012-01-01

    Psychological and neurobiological evidence implicates hippocampal-dependent memory processes in the control of hunger and food intake. In humans, these have been revealed in the hyperphagia that is associated with amnesia. However, it remains unclear whether 'memory for recent eating' plays a significant role in neurologically intact humans. In this study we isolated the extent to which memory for a recently consumed meal influences hunger and fullness over a three-hour period. Before lunch, half of our volunteers were shown 300 ml of soup and half were shown 500 ml. Orthogonal to this, half consumed 300 ml and half consumed 500 ml. This process yielded four separate groups (25 volunteers in each). Independent manipulation of the 'actual' and 'perceived' soup portion was achieved using a computer-controlled peristaltic pump. This was designed to either refill or draw soup from a soup bowl in a covert manner. Immediately after lunch, self-reported hunger was influenced by the actual and not the perceived amount of soup consumed. However, two and three hours after meal termination this pattern was reversed - hunger was predicted by the perceived amount and not the actual amount. Participants who thought they had consumed the larger 500-ml portion reported significantly less hunger. This was also associated with an increase in the 'expected satiation' of the soup 24-hours later. For the first time, this manipulation exposes the independent and important contribution of memory processes to satiety. Opportunities exist to capitalise on this finding to reduce energy intake in humans.

  14. Evaluation of putative allelochemicals in rice root exudates for their role in the suppression of arrowhead root growth.

    PubMed

    Seal, Alexa N; Haig, Terry; Pratley, James E

    2004-08-01

    In previous studies, 15 putative allelopathic compounds detected in rice root exudates were quantified by GC/MS/MS. In this study, multiple regression analysis on these compounds determined that five selected phenolics, namely caffeic, p-hydroxybenzoic, vanillic, syringic, and p-coumaric acids, from rice exudates were best correlated with the observed allelopathic effect on arrowhead (Sagittaria montevidensis) root growth. Despite this positive association, determination of the phenolic acid dose-response curve established that the amount quantified in the exudates was much lower than the required threshold concentration for arrowhead inhibition. A similar dose-response curve resulted from a combination of all 15 quantified compounds. Significant differences between the amounts of trans-ferulic acid, abietic acid, and an indole also existed between allelopathic and non-allelopathic rice cultivars. The potential roles of these three compounds in rice allelopathy were examined by chemoassay. Overall, neither the addition of trans-ferulic acid nor 5-hydroxyindole-3-acetic acid to the phenolic mix significantly contributed to phytotoxicity, although at higher concentrations, trans-ferulic acid appeared to act antagonistically to the phytotoxic effects of the phenolic mix. The addition of abietic acid also decreased the inhibitory effect of the phenolic mix. These studies indicate that the compounds quantified are not directly responsible for the observed allelopathic response. It is possible that the amount of phenolic acids may be indirectly related to the chemicals finally responsible for the observed allelopathic effect.

  15. Association Between Alcohol Consumption and Metabolic Syndrome in a Community-Based Cohort of Korean Adults

    PubMed Central

    Kim, Su Kang; Hong, Seung-Hee; Chung, Joo-Ho; Cho, Kyu Bong

    2017-01-01

    Background The relationship between alcohol consumption and metabolic syndrome (MetS) remains controversial. This study investigated the relationship between alcohol consumption and MetS components and prevalence. Material/Methods We analyzed 10 037 subjects (3076 MetS and 6961 non-MetS) in a community-based cohort. MetS was defined according to the ATP III Guidelines. Subjects were divided according to amount of alcohol consumption; non-drinker, very light (0.1–5.0 g/day), light (5.1–15.0 g/day), moderate (15.1–30.0 g/day), and heavy drinker (>30 g/day). Multiple logistic regression models were performed to estimate odds ratios (ORs) and confidence intervals (CIs). The analyses were performed in men and women separately. SPSS statistical software was used for analyses. Results The prevalence of MetS in both males and females was associated with alcohol drinking status (p<0.0001). Amount of alcohol consumption (0.1–5.0 g/day) was significantly associated with lower prevalence of MetS in both genders compared to non-drinkers. Amount of alcohol consumption (>30.0 g/day) did not show a significant association with prevalence of MetS. However, alcohol consumption (>30.0 g/day) showed an association with glucose and HDL cholesterol among the components of MetS. Conclusions Our results indicate that alcohol drinking (0.1–5.0 g/day) contributed to decrease prevalence of MetS and components, including triglyceride and HDL cholesterol. PMID:28465500

  16. Association Between Alcohol Consumption and Metabolic Syndrome in a Community-Based Cohort of Korean Adults.

    PubMed

    Kim, Su Kang; Hong, Seung-Hee; Chung, Joo-Ho; Cho, Kyu Bong

    2017-05-03

    BACKGROUND The relationship between alcohol consumption and metabolic syndrome (MetS) remains controversial. This study investigated the relationship between alcohol consumption and MetS components and prevalence. MATERIAL AND METHODS We analyzed 10 037 subjects (3076 MetS and 6961 non-MetS) in a community-based cohort. MetS was defined according to the ATP III Guidelines. Subjects were divided according to amount of alcohol consumption; non-drinker, very light (0.1-5.0 g/day), light (5.1-15.0 g/day), moderate (15.1-30.0 g/day), and heavy drinker (>30 g/day). Multiple logistic regression models were performed to estimate odds ratios (ORs) and confidence intervals (CIs). The analyses were performed in men and women separately. SPSS statistical software was used for analyses. RESULTS The prevalence of MetS in both males and females was associated with alcohol drinking status (p<0.0001). Amount of alcohol consumption (0.1-5.0 g/day) was significantly associated with lower prevalence of MetS in both genders compared to non-drinkers. Amount of alcohol consumption (>30.0 g/day) did not show a significant association with prevalence of MetS. However, alcohol consumption (>30.0 g/day) showed an association with glucose and HDL cholesterol among the components of MetS. CONCLUSIONS Our results indicate that alcohol drinking (0.1-5.0 g/day) contributed to decrease prevalence of MetS and components, including triglyceride and HDL cholesterol.

  17. Variability of Irreversible Poleward Transport in the Lower Stratosphere

    NASA Technical Reports Server (NTRS)

    Olsen, Mark; Douglass, Anne; Newman, Paul; Nash, Eric; Witte, Jacquelyn; Ziemke, Jerry

    2011-01-01

    The ascent and descent of the Brewer-Dobson circulation plays a large role in determining the distributions of many constituents in the extratropical lower stratosphere. However, relatively fast, quasi-horizontal transport out of the tropics and polar regions also significantly contribute to determining these distributions. The tropical tape recorder signal assures that there must be outflow from the tropics into the extratropical lower stratosphere. The phase of the quasi-biennial oscillation (QBO) and state of the polar vortex are known to modulate the transport from the tropical and polar regions, respectively. In this study we examine multiple years of ozone distributions in the extratropical lower stratosphere observed by the Aura Microwave Limb Sounder (MLS) and the Aura High Resolution Dynamic Limb Sounder (HIRDLS). The distributions are compared with analyses of irreversible, meridional isentropic transport. We show that there is considerable year-to-year seasonal variability in the amount of irreversible transport from the tropics, which is related to both the phase of the QBO and the state of the polar vortex. The reversibility of the transport is consistent with the number of observed breaking waves. The variability of the atmospheric index of refraction in the lower stratosphere is shown to be significantly correlated with the wave breaking and amount of irreversible transport. Finally, we will show that the seasonal extratropical stratosphere to troposphere transport of ozone can be substantially modulated by the amount of irreversible meridional transport in the lower stratosphere and we investigate how observable these differences are in data of tropospheric ozone.

  18. Nuclear energy and security

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    BLEJWAS,THOMAS E.; SANDERS,THOMAS L.; EAGAN,ROBERT J.

    2000-01-01

    Nuclear power is an important and, the authors believe, essential component of a secure nuclear future. Although nuclear fuel cycles create materials that have some potential for use in nuclear weapons, with appropriate fuel cycles, nuclear power could reduce rather than increase real proliferation risk worldwide. Future fuel cycles could be designed to avoid plutonium production, generate minimal amounts of plutonium in proliferation-resistant amounts or configurations, and/or transparently and efficiently consume plutonium already created. Furthermore, a strong and viable US nuclear infrastructure, of which nuclear power is a large element, is essential if the US is to maintain a leadershipmore » or even participatory role in defining the global nuclear infrastructure and controlling the proliferation of nuclear weapons. By focusing on new fuel cycles and new reactor technologies, it is possible to advantageously burn and reduce nuclear materials that could be used for nuclear weapons rather than increase and/or dispose of these materials. Thus, the authors suggest that planners for a secure nuclear future use technology to design an ideal future. In this future, nuclear power creates large amounts of virtually atmospherically clean energy while significantly lowering the threat of proliferation through the thoughtful use, physical security, and agreed-upon transparency of nuclear materials. The authors must develop options for policy makers that bring them as close as practical to this ideal. Just as Atoms for Peace became the ideal for the first nuclear century, they see a potential nuclear future that contributes significantly to power for peace and prosperity.« less

  19. Presence and leaching of bisphenol a (BPA) from dental materials.

    PubMed

    Becher, Rune; Wellendorf, Hanne; Sakhi, Amrit Kaur; Samuelsen, Jan Tore; Thomsen, Cathrine; Bølling, Anette Kocbach; Kopperud, Hilde Molvig

    2018-01-01

    BPA has been reported to leach from some resin based dental restorative materials and materials used for orthodontic treatment. To confirm and update previous findings, especially in light of the new temporary lower threshold value for tolerable daily BPA intake, we have investigated the leaching of BPA from 4 composite filling materials, 3 sealants and 2 orthodontic bonding materials. The materials were either uncured and dissolved in methanol or cured. The cured materials were kept in deionized water for 24 hours or 2 weeks. Samples were subsequently analyzed by ultra-performance liquid chromatography coupled to mass spectrometry (UPLC-MS-MS). The composite filling material Tetric EvoFlow ® and the fissure sealant DELTON ® showed significantly higher levels of BPA leaching compared to control samples for all test conditions (uncured, 24 h leaching and 2 weeks leaching). There were no significant differences in amount of leached BPA for any of the tested materials after 24 hours compared to 2 weeks. These results show that BPA is still released from some dental materials despite the general concern about potential adverse effects of BPA. However, the amounts of BPA were relatively low and most likely represent a very small contribution to the total BPA exposure.

  20. Mechanisms for Variation of Cellular P Stoichiometry: Diverse Cellular Phosphorus Allocation Strategies Across Microbial Groups from the Sargasso Sea

    NASA Astrophysics Data System (ADS)

    Popendorf, K.; Duhamel, S.

    2016-02-01

    Phosphorus is the least abundant of the three major macronutrients that define the canonical Redfield ratio, but its place in the backbone of nucleic acids and as an energy trafficking molecule lays a lower bound of cellular phosphorus content that is essential for all life. In addition to forming DNA, RNA, and adenosine triphosphate (ATP), significant amounts of cellular phosphorus may also be allocated to the production of phospholipids and polyphosphate. These latter two biochemicals in particular may occur in significant but highly variable amounts across different microbial groups, and the variation in cellular allocation to these biochemicals may be a contributing factor in defining the elemental stoichiometry of microbes. We investigated this variation in cellular phosphorus allocation across the most abundant microbial groups in the P-depleted Sargasso Sea: Prochlorococcus, Synechococcus, and heterotrophic bacteria. By coupling radioisotope tracing of phosphate and ATP with cell sorting flow cytometry and subsequent biochemical extractions, we made novel measurements of the P allocation to DNA, phospholipids, and polyphosphate in individual microbial groups from environmental populations. These results provide new insights into the cellular mechanisms of variation in stoichiometry and different microbial strategies for adaptation to low-P environments.

  1. Enhancing the Biological Relevance of Secretome-Based Proteomics by Linking Tumor Cell Proliferation and Protein Secretion.

    PubMed

    Gregori, Josep; Méndez, Olga; Katsila, Theodora; Pujals, Mireia; Salvans, Cándida; Villarreal, Laura; Arribas, Joaquin; Tabernero, Josep; Sánchez, Alex; Villanueva, Josep

    2014-07-15

    Secretome profiling has become a methodology of choice for the identification of tumor biomarkers. We hypothesized that due to the dynamic nature of secretomes cellular perturbations could affect their composition but also change the global amount of protein secreted per cell. We confirmed our hypothesis by measuring the levels of secreted proteins taking into account the amount of proteome produced per cell. Then, we established a correlation between cell proliferation and protein secretion that explained the observed changes in global protein secretion. Next, we implemented a normalization correcting the statistical results of secretome studies by the global protein secretion of cells into a generalized linear model (GLM). The application of the normalization to two biological perturbations on tumor cells resulted in drastic changes in the list of statistically significant proteins. Furthermore, we found that known epithelial-to-mesenchymal transition (EMT) effectors were only statistically significant when the normalization was applied. Therefore, the normalization proposed here increases the sensitivity of statistical tests by increasing the number of true-positives. From an oncology perspective, the correlation between protein secretion and cellular proliferation suggests that slow-growing tumors could have high-protein secretion rates and consequently contribute strongly to tumor paracrine signaling.

  2. Recounting a Common Experience: On the Effectiveness of Instructing Eyewitness Pairs

    PubMed Central

    Vredeveldt, Annelies; van Koppen, Peter J.

    2018-01-01

    Pairs of eyewitnesses with a content-focused interaction style remember significantly more about witnessed incidents. We examined whether content-focused retrieval strategies can be taught. Seventy-five pairs of witnesses were interviewed thrice about an event. The first and third interview were conducted individually for all witnesses. The second interview was individual, collaborative without instruction, or collaborative with instruction. Pairs in the latter condition were instructed to actively listen to and elaborate upon each other's contributions. The strategy instruction had no effect on retrieval strategies used, nor on the amount or accuracy of reported information. However, pairs who spontaneously adopted a content-focused interaction style during the collaborative interview remembered significantly more. Thus, our findings show that effective retrieval strategies cannot be taught, at least not with the current instructions. During the second interview, we observed collaborative inhibition and error pruning. When considering the total amount of information reported across the first two interviews, however, collaboration had no inhibitory effect on correct recall, yet the error pruning benefits remained. These findings suggest that investigative interviewers should interview witnesses separately first, and then interview pairs of witnesses collaboratively. PMID:29593599

  3. Glycation Reactions of Casein Micelles.

    PubMed

    Moeckel, Ulrike; Duerasch, Anja; Weiz, Alexander; Ruck, Michael; Henle, Thomas

    2016-04-13

    After suspensions of micellar casein or nonmicellar sodium caseinate had been heated, respectively, in the presence and absence of glucose for 0-4 h at 100 °C, glycation compounds were quantitated. The formation of Amadori products as indicators for the "early" Maillard reaction were in the same range for both micellar and nonmicellar caseins, indicating that reactive amino acid side chains within the micelles are accessible for glucose in a comparable way as in nonmicellar casein. Significant differences, however, were observed concerning the formation of the advanced glycation end products (AGEs), namely, N(ε)-carboxymethyllysine (CML), pyrraline, pentosidine, and glyoxal-lysine dimer (GOLD). CML could be observerd in higher amounts in nonmicellar casein, whereas in the micelles the pyrraline formation was increased. Pentosidine and GOLD were formed in comparable amounts. Furthermore, the extent of protein cross-linking was significantly higher in the glycated casein micelles than in the nonmicellar casein samples. Dynamic light scattering and scanning electron microscopy showed that glycation has no influence on the size of the casein micelles, indicating that cross-linking occurs only in the interior of the micelles, but altered the surface morphology. Studies on glycation and nonenzymatic cross-linking can contribute to the understanding of the structure of casein micelles.

  4. The contribution of skin glycosaminoglycans to the regulation of sodium homeostasis in rats.

    PubMed

    Sugár, D; Agócs, R; Tatár, E; Tóth, G; Horváth, P; Sulyok, E; Szabó, A J

    2017-08-07

    The glycosaminoglycan (GAG) molecules are a group of high molecular weight, negatively charged polysaccharides present abundantly in the mammalian organism. By their virtue of ion and water binding capacity, they may affect the redistribution of body fluids and ultimately the blood pressure. Data from the literature suggests that the mitogens Vascular Endothelial Growth Factor (VEGF)-A and VEGF-C are able to regulate the amount and charge density of GAGs and their detachment from the cell surface. Based on these findings we investigated the relationship between the level of dietary sodium intake, the expression levels of VEGF-A and VEGF-C, and the amount of the skin GAGs hyaluronic acid and chondroitin sulphate in an in vivo rat model. Significant correlation between dietary sodium intake, skin sodium levels and GAG content was found. We confirmed the GAG synthesizing role of VEGF-C but failed to prove that GAGs are degraded by VEGF-A. No significant difference in blood pressure was registered between the different dietary groups. A quotient calculated form the ion and water content of the skin tissue samples suggests that - in contrast to previous findings - the osmotically inactive ions and bound water fractions are proportional.

  5. Residual transpiration as a component of salinity stress tolerance mechanism: a case study for barley.

    PubMed

    Hasanuzzaman, Md; Davies, Noel W; Shabala, Lana; Zhou, Meixue; Brodribb, Tim J; Shabala, Sergey

    2017-06-19

    While most water loss from leaf surfaces occurs via stomata, part of this loss also occurs through the leaf cuticle, even when the stomata are fully closed. This component, termed residual transpiration, dominates during the night and also becomes critical under stress conditions such as drought or salinity. Reducing residual transpiration might therefore be a potentially useful mechanism for improving plant performance when water availability is reduced (e.g. under saline or drought stress conditions). One way of reducing residual transpiration may be via increased accumulation of waxes on the surface of leaf. Residual transpiration and wax constituents may vary with leaf age and position as well as between genotypes. This study used barley genotypes contrasting in salinity stress tolerance to evaluate the contribution of residual transpiration to the overall salt tolerance, and also investigated what role cuticular waxes play in this process. Leaves of three different positions (old, intermediate and young) were used. Our results show that residual transpiration was higher in old leaves than the young flag leaves, correlated negatively with the osmolality, and was positively associated with the osmotic and leaf water potentials. Salt tolerant varieties transpired more water than the sensitive variety under normal growth conditions. Cuticular waxes on barley leaves were dominated by primary alcohols (84.7-86.9%) and also included aldehydes (8.90-10.1%), n-alkanes (1.31-1.77%), benzoate esters (0.44-0.52%), phytol related compounds (0.22-0.53%), fatty acid methyl esters (0.14-0.33%), β-diketones (0.07-0.23%) and alkylresorcinols (1.65-3.58%). A significant negative correlation was found between residual transpiration and total wax content, and residual transpiration correlated significantly with the amount of primary alcohols. Both leaf osmolality and the amount of total cuticular wax are involved in controlling cuticular water loss from barley leaves under well irrigated conditions. A significant and negative relationship between the amount of primary alcohols and a residual transpiration implies that some cuticular wax constituents act as a water barrier on plant leaf surface and thus contribute to salinity stress tolerance. It is suggested that residual transpiration could be a fundamental mechanism by which plants optimize water use efficiency under stress conditions.

  6. 29 CFR 4.140 - Significance of contract amount.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Significance of contract amount. 4.140 Section 4.140 Labor Office of the Secretary of Labor LABOR STANDARDS FOR FEDERAL SERVICE CONTRACTS Application of the McNamara-O'Hara Service Contract Act Determining Amount of Contract § 4.140 Significance of contract amount...

  7. Badlands as a major source of petrogenic particulate Organic Carbon and sediments to the Gulf of Lion (NW Mediterranean Sea)

    NASA Astrophysics Data System (ADS)

    Copard, Y.; Eyrolle-Boyer, F.; Radakovitch, O.; Poirel, A.; Raimbault, P.; Gairoard, S.; Di-Giovanni, C.

    2017-12-01

    Rivers feed the marine environments both in term of sediments and nutrients and consequently, the characterization of their nature, sources and changes over a different spatial and time ranges is a critical for many scientific (e.g. biogeochemical cycles, contaminants transfer, geomorphology, ecology) and societal issues (e.g. food security, catastrophic floods). Specifically, continental sources showing some high erosion rates deserve to be studied since their fingerprint can be significant for the rivers fluxes. These included some sedimentary rocks (e.g. marls) forming badlands and containing a significant amount of petrogenic particulate organic carbon (pPOC) for which its contribution to the Rivers still remains evasive. Our study focuses on the Mediterranean area considered as very sensitive to the Global Change and particularly the Gulf of Lion mainly fed by the Rhône River, one of the major conveyors of sediments to this Sea. Based on radiocarbon data performed on a set of riverine samples and time series analyses from monitoring stations from French CZOs, we (i) update the POC flux of the Rhône River, (ii) determine the pPOC content and flux in suspended sediments and (iii) estimate the badlands contribution from the Durance catchment (a major tributary of the Rhône River) to the pPOC flux and to sediment discharge. Sediment discharge by the Rhône River to the Sea is 6.5 ± 4.3 Tg yr-1 (period 1990-2014) , its POC discharge reaches 0.145 ± 0.095 Tg yr-1 (period 2007-2014) while pPOC (0.44 wt. %) contributes to 30 % of this POC flux. Despite their insignificant surfaces (0.2 %) regarding the Rhône catchment area, badlands presently in erosion from the Durance catchment provide respectively, 16, 5 and 20 % of the pPOC, POC and sediment fluxes to the Rhône River. Consequently, badlands can be considered as a major source of sediments and pPOC for the NW Mediterranean Sea. We suggest that river-dominated ocean margins, such as the Rhône River, with badlands in erosion in their catchment could export a significant amount of sediments and pPOC to the oceans. According to the natural climate variability and more recently to the anthropogenic (LULUCF) disorders occurring in continental surfaces, such contributions had to and will strongly vary with times (from the geological times to the next decades scales).

  8. Contribution to the photometric determination of small amounts of boron trioxide in glasses

    NASA Technical Reports Server (NTRS)

    Markova, D.

    1985-01-01

    The photometric determination for boron trioxide is described in amounts of 0-75 micrograms B2O3 with an azomethin H reagent. The yellow colored complex which occurs in a medium held at a pH of 4.5 was measured in light of a wavelength of 415 nm.

  9. 24 CFR 941.302 - Annual contributions contract; drawdowns and advances.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... execute an ACC or ACC amendment covering the entire amount of reserved development funds or the amount of... part. This ACC or ACC amendment must be executed by both the PHA and HUD before funds can be provided... the ACC for pre-development costs for materials and services related to proposal preparation and...

  10. 24 CFR 941.302 - Annual contributions contract; drawdowns and advances.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... execute an ACC or ACC amendment covering the entire amount of reserved development funds or the amount of... part. This ACC or ACC amendment must be executed by both the PHA and HUD before funds can be provided... the ACC for pre-development costs for materials and services related to proposal preparation and...

  11. Feature selection and definition for contours classification of thermograms in breast cancer detection

    NASA Astrophysics Data System (ADS)

    Jagodziński, Dariusz; Matysiewicz, Mateusz; Neumann, Łukasz; Nowak, Robert M.; Okuniewski, Rafał; Oleszkiewicz, Witold; Cichosz, Paweł

    2016-09-01

    This contribution introduces the method of cancer pathologies detection on breast skin temperature distribution images. The use of thermosensitive foils applied to the breasts skin allows to create thermograms, which displays the amount of infrared energy emitted by all breast cells. The significant foci of hyperthermia or inflammation are typical for cancer cells. That foci can be recognized on thermograms as a contours, which are the areas of higher temperature. Every contour can be converted to a feature set that describe it, using the raw, central, Hu, outline, Fourier and colour moments of image pixels processing. This paper defines also the new way of describing a set of contours through theirs neighbourhood relations. Contribution introduces moreover the way of ranking and selecting most relevant features. Authors used Neural Network with Gevrey`s concept and recursive feature elimination, to estimate feature importance.

  12. Plant Metabolomics: An Indispensable System Biology Tool for Plant Science

    PubMed Central

    Hong, Jun; Yang, Litao; Zhang, Dabing; Shi, Jianxin

    2016-01-01

    As genomes of many plant species have been sequenced, demand for functional genomics has dramatically accelerated the improvement of other omics including metabolomics. Despite a large amount of metabolites still remaining to be identified, metabolomics has contributed significantly not only to the understanding of plant physiology and biology from the view of small chemical molecules that reflect the end point of biological activities, but also in past decades to the attempts to improve plant behavior under both normal and stressed conditions. Hereby, we summarize the current knowledge on the genetic and biochemical mechanisms underlying plant growth, development, and stress responses, focusing further on the contributions of metabolomics to practical applications in crop quality improvement and food safety assessment, as well as plant metabolic engineering. We also highlight the current challenges and future perspectives in this inspiring area, with the aim to stimulate further studies leading to better crop improvement of yield and quality. PMID:27258266

  13. The formation of molecules in interstellar clouds from singly and multiply ionized atoms

    NASA Technical Reports Server (NTRS)

    Langer, W. D.

    1978-01-01

    The suggestion is considered that multiply ionized atoms produced by K- and L-shell X-ray ionization and cosmic-ray ionization can undergo ion-molecule reactions and also initiate molecule production. The role of X-rays in molecule production in general is discussed, and the contribution to molecule production of the C(+) radiative association with hydrogen is examined. Such gas-phase reactions of singly and multiply ionized atoms are used to calculate molecular abundances of carbon-, nitrogen-, and oxygen-bearing species. The column densities of the molecules are evaluated on the basis of a modified version of previously developed isobaric cloud models. It is found that reactions of multiply ionized carbon with H2 can contribute a significant fraction of the observed CH in diffuse interstellar clouds in the presence of diffuse X-ray structures or discrete X-ray sources and that substantial amounts of CH(+) can be produced under certain conditions.

  14. Cometary material and the origins of life on earth

    NASA Technical Reports Server (NTRS)

    Lazcano-Araujo, A.; Oro, J.

    1981-01-01

    The role of cometary material in determining the environmental conditions of the prebiotic earth is reviewed. The organic synthesis pathways that occur in dense interstellar clouds and in comets are examined, and complex organic molecules believed to exist (amino acids, carboxylic acids, purines, pyrimidines and hydrocarbons) based on spectral detections of degradation products are noted. Estimates of the amount of terrestrial volatiles of cometary origin that may have been acquired in collisions during the early history of the earth are considered, and shown to dominate any estimated contributions to terrestrial carbon from other extraterrestrial sources. Current evidence that the origin and early evolution of life began about four billion years ago is discussed in relation to the cometary bombardment processes occurring at the time and the resultant shock waves, reducing atmospheres and reactive chemical species. It is thus concluded that comets contributed significantly to the processes of chemical evolution necessary for the emergence of life on earth.

  15. Muscle characteristics only partially explain color variations in fresh hams.

    PubMed

    Stufft, K; Elgin, J; Patterson, B; Matarneh, S K; Preisser, R; Shi, H; England, E M; Scheffler, T L; Mills, E W; Gerrard, D E

    2017-06-01

    Fresh hams display significant lean color variation that persists through further processing and contributes to a less desirable cured product. In an attempt to understand the underlying cause of this color disparity, we evaluated the differences in muscle characteristics and energy metabolites across semimembranosus (SM) muscles differing in color variation. The L* (lightness) and a* (redness) values were highest and lowest (P<0.001), respectfully in the most caudal aspects of the muscle while the ultimate pH was the lowest (P<0.001). Correspondingly, this region possessed highest (P<0.01) glycolytic potential (GP) and lactate dehydrogenase (LDH) levels but did not differ in the amount of myoglobin or myosin heavy chain type I isoform. These data show that differences in muscle may contribute to ham color variation but suggest other factors may mitigate or exacerbate these variances. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Catching up? The educational mobility of migrants’ and natives’ children in Europe

    PubMed Central

    Oberdabernig, Doris; Schneebaum, Alyssa

    2017-01-01

    ABSTRACT Migrants into European countries are often less educated than European natives. We analyse whether migrants’ children are more or less likely than natives’ children to achieve upward educational mobility across generations, and study differences in the factors, which contribute to differences in mobility for the two groups. We find that migrants’ descendants are more often upwardly mobile (and less often downwardly mobile) than their native peers in the majority of countries studied, and show that the main factor contributing to these patterns is the education level of parents. Although a lower parental education means that their children are less likely to access the same amount of human, social and financial capital as children of more highly educated parents, migrants’ descendants over the last two generations were able to make significant progress in reducing education gaps with natives. PMID:28620245

  17. Plant Metabolomics: An Indispensable System Biology Tool for Plant Science.

    PubMed

    Hong, Jun; Yang, Litao; Zhang, Dabing; Shi, Jianxin

    2016-06-01

    As genomes of many plant species have been sequenced, demand for functional genomics has dramatically accelerated the improvement of other omics including metabolomics. Despite a large amount of metabolites still remaining to be identified, metabolomics has contributed significantly not only to the understanding of plant physiology and biology from the view of small chemical molecules that reflect the end point of biological activities, but also in past decades to the attempts to improve plant behavior under both normal and stressed conditions. Hereby, we summarize the current knowledge on the genetic and biochemical mechanisms underlying plant growth, development, and stress responses, focusing further on the contributions of metabolomics to practical applications in crop quality improvement and food safety assessment, as well as plant metabolic engineering. We also highlight the current challenges and future perspectives in this inspiring area, with the aim to stimulate further studies leading to better crop improvement of yield and quality.

  18. The role of Gouy phase on the mechanical effects of Laguerre-Gaussian light interacting with atoms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lembessis, V. E., E-mail: vlempesis@ksu.edu.sa; Babiker, M.; Ellinas, D.

    2016-06-10

    We consider the case of Laguerre-Gaussian (LG) light with high values of radial index, p, and/or winding number l, focussing on the effects of the Gouy phase together with other phase contributions due to the curvature in a Laguerre Gaussian beam when it interacts with atoms at near resonance. We show here that these phase anomalies amount to a significant reduction of the axial wavevector and thus lead to additional contributions to the phase gradient in the vicinity of the focus plane. In consequence, the axial recoil effects due to the stimulated emission and absorption of light by the atommore » become smaller. This has important effects on the dissipative axial forces acting on the atom, on the momentum fluctuations associated with the photon absorption and stimulated emission and on diffraction of atoms through light masks created by LG beams.« less

  19. Bioremediation of high-strength agricultural wastewater using Ochrobactrum sp. strain SZ1.

    PubMed

    Neoh, Chin Hong; Lam, Chi Yong; Ghani, Suriati Mat; Ware, Ismail; Sarip, Siti Hajar Mat; Ibrahim, Zaharah

    2016-12-01

    The biggest agricultural sector that contributes to the Malaysian economy is the oil palm industry. The effluent generated during the production of crude palm oil known as palm oil mill effluent (POME). POME undergoes anaerobic treatment that requires long retention time and produces large amount of methane that consequently contributes to global warming. In this study, an isolated bacteria was selected based on its ability to degrade kraft lignin (KL) and identified as Ochrobactrum sp. The bacteria were able to treat POME (from anaerobic pond) under the aerobic condition without addition of nutrient, resulting in a significant chemical oxygen demand (COD) removal of 71 %, removal rate of 1385 mg/l/day, and 12.3 times higher than that of the ponding system. It has also resulted in 60 % removal of ammoniacal nitrogen and 55 % of total polyphenolic after 6-day treatment period with the detection of lignocellulolytic enzymes.

  20. Multiple scattering in the remote sensing of natural surfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Wen-Hao; Weeks, R.; Gillespie, A.R.

    1996-07-01

    Radiosity models predict the amount of light scattered many times (multiple scattering) among scene elements in addition to light interacting with a surface only once (direct reflectance). Such models are little used in remote sensing studies because they require accurate digital terrain models and, typically, large amounts of computer time. We have developed a practical radiosity model that runs relatively quickly within suitable accuracy limits, and have used it to explore problems caused by multiple-scattering in image calibration, terrain correction, and surface roughness estimation for optical images. We applied the radiosity model to real topographic surfaces sampled at two verymore » different spatial scales: 30 m (rugged mountains) and 1 cm (cobbles and gravel on an alluvial fan). The magnitude of the multiple-scattering (MS) effect varies with solar illumination geometry, surface reflectivity, sky illumination and surface roughness. At the coarse scale, for typical illumination geometries, as much as 20% of the image can be significantly affected (>5%) by MS, which can account for as much as {approximately}10% of the radiance from sunlit slopes, and much more for shadowed slopes, otherwise illuminated only by skylight. At the fine scale, radiance from as much as 30-40% of the scene can have a significant MS component, and the MS contribution is locally as high as {approximately}70%, although integrating to the meter scale reduces this limit to {approximately}10%. Because the amount of MS increases with reflectivity as well as roughness, MS effects will distort the shape of reflectance spectra as well as changing their overall amplitude. The change is proportional to surface roughness. Our results have significant implications for determining reflectivity and surface roughness in remote sensing.« less

  1. Improved Method for Isolation of Microbial RNA from Biofuel Feedstock for Metatranscriptomics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Piao, Hailan; Markillie, Lye Meng; Culley, David E.

    2013-03-28

    Metatranscriptomics—gene express profiling via DNA sequencing—is a powerful tool to identify genes that are ac- tively expressed and might contribute to the phenotype of individual organisms or the phenome (the sum of several phenotypes) of a microbial community. Furthermore, metatranscriptome studies can result in extensive catalogues of genes that encode for enzymes of industrial relevance. In both cases, a major challenge for generating a high quality metatranscriptome is the extreme lability of RNA and its susceptibility to ubiquitous RNAses. The microbial commu- nity (the microbiome) of the cow rumen efficiently degrades lignocelullosic biomass, generates significant amounts of methane, a greenhousemore » gas twenty times more potent than carbon dioxide, and is of general importance for the physio- logical wellbeing of the host animal. Metatranscriptomes of the rumen microbiome from animals kept under different conditions and from various types of rumen-incubated biomass can be expected to provide new insights into these highly interesting phenotypes and subsequently provide the framework for an enhanced understanding of this socio- economically important ecosystem. The ability to isolate large amounts of intact RNA will significantly facilitate accu- rate transcript annotation and expression profiling. Here we report a method that combines mechanical disruption with chemical homogenization of the sample material and consistently yields 1 mg of intact RNA from 1 g of rumen-in- cubated biofuel feedstock. The yield of total RNA obtained with our method exceeds the RNA yield achieved with pre- viously reported isolation techniques, which renders RNA isolated with the method presented here as an ideal starting material for metatranscriptomic analyses and other molecular biology applications that require significant amounts of starting material.« less

  2. Hib antibody responses in infants following diphtheria, tetanus, acellular pertussis, and conjugated Haemophilus influenzae type b (Hib) combination vaccines with decreasing amounts of tetanus toxoid.

    PubMed

    Bernstein, Henry H; Seyferth, Elisabeth R

    2017-12-04

    While combination vaccines have contributed to improved vaccine uptake rates in children, studies have documented varied immunogenicity to specific vaccine components. We studied whether varying the amount of tetanus toxoid (TT) in a DTaP and Hib combination vaccine would result in immunogenicity comparable with separate, concurrent administration. We evaluated the immunogenicity of Massachusetts Biologic Laboratories (MBL) diphtheria, tetanus, and acellular pertussis (mDTaP) vaccine combined with tetanus-conjugated MBL Haemophilus influenzae type b vaccine (mHib) in a single injection (DTaPH). We compared four DTaPH vaccines containing varying concentrations of TT. We also evaluated the immune response to the DTaP vaccine manufactured by Connaught Laboratories (now known as Sanofi Pasteur) given with mHib and with Wyeth Hib-CRM 197 (HbOC) as separate injections. Vaccines were administered to 240 healthy infants at 2, 4, and 6 months of age, and blood specimens for antibody determination were obtained before each immunization and one month after the third immunization. We found no significant differences in immune response to the vaccines between the four DTaPH groups. Hib antibody responses were similar in the mHib and the HbOC groups but significantly lower in the DTaPH groups, as measured by Chinese Hamster Ovary (CHO) cell neutralization titers and filamentous hemagglutinin antigen (FHA) geometric mean concentrations (GMC) of anti-Hib antibodies. There were no significant differences between the groups in pertussis or tetanus toxoid antibody levels. Reducing tetanus toxoid amounts did not produce comparable immunogenicity for Hib. The nature of the interaction between immune responses to DTaPH components should be explored further to enable the development of better Hib-containing combination vaccines. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Genome size evolution in relation to leaf strategy and metabolic rates revisited.

    PubMed

    Beaulieu, Jeremy M; Leitch, Ilia J; Knight, Charles A

    2007-03-01

    It has been proposed that having too much DNA may carry physiological consequences for plants. The strong correlation between DNA content, cell size and cell division rate could lead to predictable morphological variation in plants, including a negative relationship with leaf mass per unit area (LMA). In addition, the possible increased demand for resources in species with high DNA content may have downstream effects on maximal metabolic efficiency, including decreased metabolic rates. Tests were made for genome size-dependent variation in LMA and metabolic rates (mass-based photosynthetic rate and dark respiration rate) using our own measurements and data from a plant functional trait database (Glopnet). These associations were tested using two metrics of genome size: bulk DNA amount (2C DNA) and monoploid genome size (1Cx DNA). The data were analysed using an evolutionary framework that included a regression analysis and independent contrasts using a phylogenetic tree with estimates of molecular diversification times. A contribution index for the LMA data set was also calculated to determine which divergences have the greatest influence on the relationship between genome size and LMA. A significant negative association was found between bulk DNA amount and LMA in angiosperms. This was primarily a result of influential divergences that may represent early shifts in growth form. However, divergences in bulk DNA amount were positively associated with divergences in LMA, suggesting that the relationship may be indirect and mediated through other traits directly related to genome size. There was a significant negative association between genome size and metabolic rates that was driven by a basal divergence between angiosperms and gymnosperms; no significant independent contrast results were found. Therefore, it is concluded that genome size-dependent constraints acting on metabolic efficiency may not exist within seed plants.

  4. Sources of Magmatic Volatiles Discharging from Subduction Zone Volcanoes

    NASA Astrophysics Data System (ADS)

    Fischer, T.

    2001-05-01

    Subduction zones are locations of extensive element transfer from the Earth's mantle to the atmosphere and hydrosphere. This element transfer is significant because it can, in some fashion, instigate melt production in the mantle wedge. Aqueous fluids are thought to be the major agent of element transfer during the subduction zone process. Volatile discharges from passively degassing subduction zone volcanoes should in principle, provide some information on the ultimate source of magmatic volatiles in terms of the mantle, the crust and the subducting slab. The overall flux of volatiles from degassing volcanoes should be balanced by the amount of volatiles released from the mantle wedge, the slab and the crust. Kudryavy Volcano, Kurile Islands, has been passively degassing at 900C fumarole temperatures for at least 40 years. Extensive gas sampling at this basaltic andesite cone and application of CO2/3He, N2/3He systematics in combination with C and N- isotopes indicates that 80% of the CO2 and approximately 60% of the N 2 are contributed from a sedimentary source. The mantle wedge contribution for both volatiles is, with 12% and 17% less significant. Direct volatile flux measurements from the volcano using the COSPEC technique in combination with direct gas sampling allows for the calculation of the 3He flux from the volcano. Since 3He is mainly released from the astenospheric mantle, the amount of mantle supplying the 3He flux can be determined if initial He concentrations of the mantle melts are known. The non-mantle flux of CO2 and N2 can be calculated in similar fashion. The amount of non-mantle CO2 and N2 discharging from Kudryavy is balanced by the amount of CO2 and N2 subducted below Kudryavy assuming a zone of melting constrained by the average spacing of the volcanoes along the Kurile arc. The volatile budget for Kudryavy is balanced because the volatile flux from the volcano is relatively small (75 t/day (416 Mmol/a) SO2, 360 Mmol/a of non-mantle CO2 and 5.4 Mmol/a of non-mantle N2). Other subduction zone volcanoes are currently degassing a much more substantial amount of volatiles. Popocatepetl, Mexico, has degassed approximately 14 Mt of SO2 to the atmosphere over the past 6 years (Witter et al. 2000). Satsuma-Iwojima, Japan, has degassed for longer than 800 years and is currently releasing 500-1000 tones/day (Kazahaya et al. 2000). At these volcanoes CO2 and N2 discharges from the magma should also be balanced by the supply from slab and crustal sources. The rate of subduction off Mexico and Japan, however, is similar to the rate at the Kuriles. Therefore, large amounts of slab derived volatiles must be, in some fashion, stored in the "subduction factory" to supply the large amounts degassing passively from these volcanoes. Kazahaya et al. (2000) Seventh Field Workshop on Volcanic Gases, IAVCEI. Witter et al (2000) Seventh Field Workshop on Volcanic Gases, IAVCEI.

  5. Antioxidant synergistic effects of Osmanthus fragrans flowers with green tea and their major contributed antioxidant compounds.

    PubMed

    Mao, Shuqin; Wang, Kaidi; Lei, Yukun; Yao, Shuting; Lu, Baiyi; Huang, Weisu

    2017-04-19

    The antioxidant synergistic effects of Osmanthus fragrans flowers with green tea were evaluated, and their major antioxidant compounds contributed to the total amount of synergy were determined. The antioxidant compounds in O. fragrans flowers with green tea were identified by LC-MS and quantified by UPLC-PDA. The synergistic antioxidant interactions between O. fragrans flowers with green tea and their antioxidant compounds were tested using the Prieto's model after the simulated digestion. The main antioxidant compounds in O. fragrans flowers were acteoside and salideroside, whereas the main antioxidant compounds in green tea were caffeine, gallic acid, and L-epicatechin. The significant synergistic effect between O. fragrans flowers and green tea was observed and among nearly all of the combinations of their antioxidant compounds. Among the combinations, acteoside and gallic acid contributed most to the antioxidant synergy between O. fragrans flowers and green tea. However, the simulated digestion decreased this antioxidant synergy because it reduced the contents and the antioxidant capacities of their compounds, as well as the antioxidant synergy among the compounds.

  6. Estimation of continental precipitation recycling

    NASA Technical Reports Server (NTRS)

    Brubaker, Kaye L.; Entekhabi, Dara; Eagleson, P. S.

    1993-01-01

    The total amount of water that precipitates on large continental regions is supplied by two mechanisms: 1) advection from the surrounding areas external to the region and 2) evaporation and transpiration from the land surface within the region. The latter supply mechanism is tantamount to the recycling of precipitation over the continental area. The degree to which regional precipitation is supplied by recycled moisture is a potentially significant climate feedback mechanism and land surface-atmosphere interaction, which may contribute to the persistence and intensification of droughts. Gridded data on observed wind and humidity in the global atmosphere are used to determine the convergence of atmospheric water vapor over continental regions. A simplified model of the atmospheric moisture over continents and simultaneous estimates of regional precipitation are employed to estimate, for several large continental regions, the fraction of precipitation that is locally derived. The results indicate that the contribution of regional evaporation to regional precipitation varies substantially with location and season. For the regions studied, the ratio of locally contributed to total monthly precipitation generally lies between 0. 10 and 0.30 but is as high as 0.40 in several cases.

  7. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contribution of women's coats which were section 1221(1) property. The fair market value of the property at the... section, and the donor's cost of goods sold for the year of contribution must be adjusted under paragraph... donor's deduction is reduced to the amount allowable under section 170 of the regulations thereunder...

  8. P-glycoprotein (Mdr1a/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain

    PubMed Central

    Porteous, Carolyn M.; Menon, David K.; Aigbirhio, Franklin I.; Smith, Robin A.J.; Murphy, Michael P.

    2013-01-01

    Background Mitochondrial dysfunction contributes to degenerative neurological disorders, consequently there is a need for mitochondria-targeted therapies that are effective within the brain. One approach to deliver pharmacophores is by conjugation to the lipophilic triphenylphosphonium (TPP) cation that accumulates in mitochondria driven by the membrane potential. While this approach has delivered TPP-conjugated compounds to the brain, the amounts taken up are lower than by other organs. Methods To discover why uptake of hydrophobic TPP compounds by the brain is relatively poor, we assessed the role of the P-glycoprotein (Mdr1a/b) and breast cancer resistance protein (Bcrp) ATP binding cassette (ABC) transporters, which drive the efflux of lipophilic compounds from the brain thereby restricting the uptake of lipophilic drugs. We used a triple transgenic mouse model lacking two isoforms of P-glycoprotein (Mdr1a/1b) and the Bcrp. Results There was a significant increase in the uptake into the brain of two hydrophobic TPP compounds, MitoQ and MitoF, in the triple transgenics following intra venous (IV) administration compared to control mice. Greater amounts of the hydrophobic TPP compounds were also retained in the liver of transgenic mice compared to controls. The uptake into the heart, white fat, muscle and kidneys was comparable between the transgenic mice and controls. Conclusion Efflux of hydrophobic TPP compounds by ABC transporters contributes to their lowered uptake into the brain and liver. General significance These findings suggest that strategies to bypass ABC transporters in the BBB will enhance delivery of mitochondria-targeted antioxidants, probes and pharmacophores to the brain. PMID:23454352

  9. Interpreting consumer preferences: physicohedonic and psychohedonic models yield different information in a coffee-flavored dairy beverage.

    PubMed

    Li, Bangde; Hayes, John E; Ziegler, Gregory R

    2014-09-01

    Designed experiments provide product developers feedback on the relationship between formulation and consumer acceptability. While actionable, this approach typically assumes a simple psychophysical relationship between ingredient concentration and perceived intensity. This assumption may not be valid, especially in cases where perceptual interactions occur. Additional information can be gained by considering the liking-intensity function, as single ingredients can influence more than one perceptual attribute. Here, 20 coffee-flavored dairy beverages were formulated using a fractional mixture design that varied the amount of coffee extract, fluid milk, sucrose, and water. Overall liking ( liking ) was assessed by 388 consumers using an incomplete block design (4 out of 20 prototypes) to limit fatigue; all participants also rated the samples for intensity of coffee flavor (coffee) , milk flavor (milk) , sweetness (sweetness) and thickness (thickness) . Across product means, the concentration variables explained 52% of the variance in liking in main effects multiple regression. The amount of sucrose (β = 0.46) and milk (β = 0.46) contributed significantly to the model (p's <0.02) while coffee extract (β = -0.17; p = 0.35) did not. A comparable model based on the perceived intensity explained 63% of the variance in mean liking ; sweetness (β = 0.53) and milk (β = 0.69) contributed significantly to the model (p's <0.04), while the influence of coffee flavor (β = 0.48) was positive but marginally (p = 0.09). Since a strong linear relationship existed between coffee extract concentration and coffee flavor, this discrepancy between the two models was unexpected, and probably indicates that adding more coffee extract also adds a negative attribute, e.g. too much bitterness. In summary, modeling liking as a function of both perceived intensity and physical concentration provides a richer interpretation of consumer data.

  10. Interpreting consumer preferences: physicohedonic and psychohedonic models yield different information in a coffee-flavored dairy beverage

    PubMed Central

    Li, Bangde; Hayes, John E.; Ziegler, Gregory R.

    2014-01-01

    Designed experiments provide product developers feedback on the relationship between formulation and consumer acceptability. While actionable, this approach typically assumes a simple psychophysical relationship between ingredient concentration and perceived intensity. This assumption may not be valid, especially in cases where perceptual interactions occur. Additional information can be gained by considering the liking-intensity function, as single ingredients can influence more than one perceptual attribute. Here, 20 coffee-flavored dairy beverages were formulated using a fractional mixture design that varied the amount of coffee extract, fluid milk, sucrose, and water. Overall liking (liking) was assessed by 388 consumers using an incomplete block design (4 out of 20 prototypes) to limit fatigue; all participants also rated the samples for intensity of coffee flavor (coffee), milk flavor (milk), sweetness (sweetness) and thickness (thickness). Across product means, the concentration variables explained 52% of the variance in liking in main effects multiple regression. The amount of sucrose (β = 0.46) and milk (β = 0.46) contributed significantly to the model (p’s <0.02) while coffee extract (β = −0.17; p = 0.35) did not. A comparable model based on the perceived intensity explained 63% of the variance in mean liking; sweetness (β = 0.53) and milk (β = 0.69) contributed significantly to the model (p’s <0.04), while the influence of coffee flavor (β = 0.48) was positive but marginally (p = 0.09). Since a strong linear relationship existed between coffee extract concentration and coffee flavor, this discrepancy between the two models was unexpected, and probably indicates that adding more coffee extract also adds a negative attribute, e.g. too much bitterness. In summary, modeling liking as a function of both perceived intensity and physical concentration provides a richer interpretation of consumer data. PMID:25024507

  11. Nitrogen incorporation in carbon nitride films produced by direct and dual ion-beam sputtering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abrasonis, G.; Gago, R.; Jimenez, I.

    2005-10-01

    Carbon (C) and carbon nitride (CN{sub x}) films were grown on Si(100) substrates by direct ion-beam sputtering (IBS) of a carbon target at different substrate temperatures (room temperature-450 deg. C) and Ar/N{sub 2} sputtering gas mixtures. Additionally, the effect of concurrent nitrogen-ion assistance during the growth of CN{sub x} films by IBS was also investigated. The samples were analyzed by elastic recoil detection analysis (ERDA) and x-ray absorption near-edge spectroscopy (XANES). The ERDA results showed that significant nitrogen amount (up to 20 at. %) was incorporated in the films, without any other nitrogen source but the N{sub 2}-containing sputtering gas.more » The nitrogen concentration is proportional to the N{sub 2} content in the sputtering beam and no saturation limit is reached under the present working conditions. The film areal density derived from ERDA revealed a decrease in the amount of deposited material at increasing growth temperature, with a correlation between the C and N losses. The XANES results indicate that N atoms are efficiently incorporated into the carbon network and can be found in different bonding environments, such as pyridinelike, nitrilelike, graphitelike, and embedded N{sub 2} molecules. The contribution of molecular and pyridinelike nitrogen decreases when the temperature increases while the contribution of the nitrilelike nitrogen increases. The concurrent nitrogen ion assistance resulted in the significant increase of the nitrogen content in the film but it induced a further reduction of the deposited material. Additionally, the assisting ions inhibited the formation of the nitrilelike configurations while promoting nitrogen environments in graphitelike positions. The nitrogen incorporation and release mechanisms are discussed in terms of film growth precursors, ion bombardment effects, and chemical sputtering.« less

  12. Leaf fatty acid remodeling in the salt-excreting halophytic grass Spartina patens along a salinity gradient.

    PubMed

    Duarte, Bernardo; Matos, Ana Rita; Marques, João Carlos; Caçador, Isabel

    2018-03-01

    Spartina patens is a highly dispersed halophytic grass invader in Mediterranean marshes. It is also characterized by having a high degree of resistance to salinity, one of the main drivers of plant zonation in salt marshes. Nevertheless, the physiological basis behind the extreme resistance of S. patens requires more detailed studies. In the present work, we aimed to study how membrane fatty acid remodeling could contribute to the resistance of this plant to salt. Spartina patens individuals exposed to increasing levels of salinity and its leaf fatty acid profile under lipid peroxidation products evaluated under all tested concentrations. A significant increase in the relative amounts of the saturated fatty acids (SFA) was observed, namely palmitic acid (C16:0), essential for PS II functioning, and stearic (C18:0) acid. The chloroplastidial trans-hexadecenoic acid (C16:1t) as well as the polyunsaturated linoleic (C18:2) and linolenic (C18:3) acids showed significant decreases in all the salt treatments. These changes led to a reduction in the double bond index in salt-treated plants which reflects reduction of the fluidity of the chloroplast membranes, which could contribute to maintain the membrane impermeable to the toxic exogenous Na. Despite the decrease observed in the total fatty acid contents in plants exposed to high salt concentrations the amounts of lipid peroxidation products decreased highlighting the resistance of this species towards toxic exogenous salt concentrations. Membrane fatty acid remodeling could represent an efficient mechanism to maintain the photosynthetic machinery of S. patens highly efficient under salt stress. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

  13. Bioaccessibility and Speciation of Potential Toxicants in Some Geogenic Sources of Atmospheric Particulate Matter

    NASA Astrophysics Data System (ADS)

    Morman, S. A.; Wolf, R. E.; Plumlee, G.; Reynolds, R. L.

    2008-12-01

    The correlation of exposure to particulate matter (PM) and increased morbidity and mortality was established in the 1970's. Research focused on elucidating mechanisms of action (i.e. particle size, composition, and biodurability), has generally examined anthropogenic sources such as solid or liquid combustion byproducts of fossil fuels, byproducts from the smelting of metal ores, and commercial/industrial mineral dusts (asbestos, crystalline silica. metal dusts). While many studies exist on agricultural exposures to inorganic dust, far fewer have examined health issues related to particulate matter contributions from rural, non-agricultural dusts or other geogenic sources. Geogenic PM (produced by natural processes such as volcanic ash, volcanic fog (vog), dusts from dry lakes or glacial deposits, smoke and windborne ash from wildfires, and dusts containing various soil pathogens) and geoanthropogenic PM (produced from natural sources by processes that are modified or enhanced by human activities such as dusts from lakebeds dried by human removal of water, dusts produced from areas that have undergone desertification as a result of human practices etc.) are increasingly recognized as potential agents of toxicity and disease, via both environmental and occupational exposures. Surface sediment on some dry lake beds may contribute significant amounts of mineral dusts to the atmospheric load. For example, Owens Lake (a dry lake in southern California) has been a major source of PM10 (particulate matter less than 10 micrometers) dust in the United States. Dusts from dry and drying saline lakes may contain high concentrations of metals, such as arsenic, with known human health toxicity. Wildfires, consuming over nine million acres in 2007, also contribute significant amounts of particulate matter in addition to their other hazards. Designed to estimate the bioaccessibility of metals in soils, dusts and other environmental materials by measuring the reactivity of the materials in simulated body fluids (SBFs), physiologically based extraction tests (PBETs) are an inexpensive, acellular in vitro test. Bioaccessibility, defined as the fraction of a potential toxicant that becomes soluble in the SBF (e.g. gastric, intestinal, lung or lysosomal fluid), is an indication of the amounts of a potential toxicant that may be available for absorption through ingestion or inhalation. PBETs were conducted on artificially generated dust samples from playas in the Mojave Desert and soil and ash samples from recent California wildfires. Speciation, an important factor in assessing toxicity, was evaluated using high performance liquid chromatography (HPLC) separation with ICP-MS detection for arsenic and chromium.

  14. 14 CFR 1240.110 - Recommendation to the Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Recommendation to the Administrator. 1240... AND CONTRIBUTIONS Awards for Scientific and Technical Contributions § 1240.110 Recommendation to the... specific amount and distribution thereof for any multiple contributors. The recommendation of the Board to...

  15. 14 CFR 1240.110 - Recommendation to the Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Recommendation to the Administrator. 1240... AND CONTRIBUTIONS Awards for Scientific and Technical Contributions § 1240.110 Recommendation to the... specific amount and distribution thereof for any multiple contributors. The recommendation of the Board to...

  16. O3 Source Contribution During a Heavy O3 Pollution Episode in Shanghai China

    EPA Science Inventory

    Source culpability assessments are useful for developing effective emission control strategies. The Integrated Source Apportionment Method (ISAM) has been implemented in CMAQ to track contributions from source groups and regions to ambient levels and deposited amounts of O3. CMAQ...

  17. 5 CFR 842.907 - Withholding and contributions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Section 842.907 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE... required under 5 U.S.C. 8422(a)(3) and submit that amount to OPM in accordance with payroll office... payroll office instructions issued by OPM. (c) If the correct withholding and/or Government contributions...

  18. 5 CFR 1605.11 - Makeup of missed or insufficient contributions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... associated breakage to the participant's account in accordance with § 1605.2. (c) Employee makeup... employing agency acknowledges that an error has occurred which has caused a smaller amount of employee... establish a schedule to make up the deficient contributions through future payroll deductions. Employee...

  19. The Variation of Tropical Cyclone Rainfall within the North Atlantic and Pacific as Observed from Satellites

    NASA Technical Reports Server (NTRS)

    Rodgers, Edward; Pierce, Harold; Adler, Robert

    1999-01-01

    Tropical cyclone monthly rainfall amounts are estimated from passive microwave satellite observations in the North Atlantic and in three equal geographical regions of the North Pacific (i.e., Western, Central, and Eastern North Pacific). These satellite-derived rainfall amounts are used to assess the impact of tropical cyclone rainfall in altering the geographical, seasonal, and inter-annual distribution of the 1987-1989, 1991-1998 North Atlantic and Pacific rainfall during June-November when tropical cyclones are most abundant. To estimate these tropical cyclone rainfall amounts, mean monthly rain rates are derived from the Defence Meteorological Satellite Program (DMSP) Special Sensor Microwave/ Radiometer (SSM/I) observations within 444 km radius of the center of those North Atlantic and Pacific tropical cyclones that reached storm stage and greater. These rain rate observations are then multiplied by the number of hours in a given month. Mean monthly rainfall amounts are also constructed for all the other North Atlantic and Pacific raining systems during this eleven year period for the purpose of estimating the geographical distribution and intensity of rainfall contributed by non-tropical cyclone systems. Further, the combination of the non-tropical cyclone and tropical cyclone (i.e., total) rainfall is constructed to delineate the fractional amount that tropical cyclones contributed to the total North Pacific rainfall.

  20. Recall is not necessary for verbal sequence learning.

    PubMed

    Kalm, Kristjan; Norris, Dennis

    2016-01-01

    The question of whether overt recall of to-be-remembered material accelerates learning is important in a wide range of real-world learning settings. In the case of verbal sequence learning, previous research has proposed that recall either is necessary for verbal sequence learning (Cohen & Johansson Journal of Verbal Learning and Verbal Behavior, 6, 139-143, 1967; Cunningham, Healy, & Williams Journal of Experimental Psychology: Learning, Memory, and Cognition, 10, 575-597, 1984), or at least contributes significantly to it (Glass, Krejci, & Goldman Journal of Memory and Language, 28, 189-199, 1989; Oberauer & Meyer Memory, 17, 774-781, 2009). In contrast, here we show that the amount of previous spoken recall does not predict learning and is not necessary for it. We suggest that previous research may have underestimated participants' learning by using suboptimal performance measures, or by using manual or written recall. However, we show that the amount of spoken recall predicted how much interference from other to-be-remembered sequences would be observed. In fact, spoken recall mediated most of the error learning observed in the task. Our data support the view that the learning of overlapping auditory-verbal sequences is driven by learning the phonological representations and not the articulatory motor responses. However, spoken recall seems to reinforce already learned representations, whether they are correct or incorrect, thus contributing to a participant identifying a specific stimulus as either "learned" or "new" during the presentation phase.

  1. Substantial Effect of Melanin Influencing Factors on In vitro Melanogenesis in Muzzle Melanocytes of Differently Colored Hanwoo.

    PubMed

    Amna, Touseef; Park, Kyoung Mi; Cho, In-Kyung; Choi, Tae Jeong; Lee, Seung Soo; Seo, Kang-Seok; Hwang, Inho

    2012-07-01

    The present study was designed to investigate the effect of α-melanocyte-stimulating hormone (α-MSH), nitric oxide (NO) and L-cysteine on melanin production and expression of related genes MC1R, Tyr, Tyrp-1 and Tyrp-2 in muzzle melanocytes of differently colored three native Hanwoo cattle. Muzzle samples were taken from black, brindle and brown Hanwoo and purified melanocytes were cultured with α-MSH, nitric oxide and L-cysteine at 100 nM, 50 µM and 0.07 mg/ml of media respectively. The amounts of total melanin, eumelanin and mRNA expression at Tyr, Tyrp-1, Tyrp-2 and MC1R levels were quantified. α-MSH and nitric oxide significantly increased (p<0.05) the amount of total melanin in black and brindle whereas eumelanin production in brown Hanwoo muzzle melanocytes. On the contrary, L-cysteine greatly (p<0.05) depressed the eumelanin production in black color but increased in brown. Simultaneously, up regulation of Tyr by nitric oxide and α-MSH and down regulation of Tyr, Tyrp-2 and MC1R genes by L-cysteine were observed in muzzle melanocytes of all three phenotypes. The results of this study revealed nitric oxide and α-MSH contribute hyper-pigmentation by enhancing eumelanogenesis whereas L-cysteine contributes to pheomelanin production in different colored Hanwoo muzzle melanocytes.

  2. Substantial Effect of Melanin Influencing Factors on In vitro Melanogenesis in Muzzle Melanocytes of Differently Colored Hanwoo

    PubMed Central

    Amna, Touseef; Park, Kyoung Mi; Cho, In-Kyung; Choi, Tae Jeong; Lee, Seung Soo; Seo, Kang-Seok; Hwang, Inho

    2012-01-01

    The present study was designed to investigate the effect of α-melanocyte-stimulating hormone (α-MSH), nitric oxide (NO) and L-cysteine on melanin production and expression of related genes MC1R, Tyr, Tyrp-1 and Tyrp-2 in muzzle melanocytes of differently colored three native Hanwoo cattle. Muzzle samples were taken from black, brindle and brown Hanwoo and purified melanocytes were cultured with α-MSH, nitric oxide and L-cysteine at 100 nM, 50 µM and 0.07 mg/ml of media respectively. The amounts of total melanin, eumelanin and mRNA expression at Tyr, Tyrp-1, Tyrp-2 and MC1R levels were quantified. α-MSH and nitric oxide significantly increased (p<0.05) the amount of total melanin in black and brindle whereas eumelanin production in brown Hanwoo muzzle melanocytes. On the contrary, L-cysteine greatly (p<0.05) depressed the eumelanin production in black color but increased in brown. Simultaneously, up regulation of Tyr by nitric oxide and α-MSH and down regulation of Tyr, Tyrp-2 and MC1R genes by L-cysteine were observed in muzzle melanocytes of all three phenotypes. The results of this study revealed nitric oxide and α-MSH contribute hyper-pigmentation by enhancing eumelanogenesis whereas L-cysteine contributes to pheomelanin production in different colored Hanwoo muzzle melanocytes. PMID:25049660

  3. The contribution of medializing calcaneal osteotomy on hindfoot alignment in the reconstruction of the stage II adult acquired flatfoot deformity.

    PubMed

    Chan, Jeremy Y; Williams, Benjamin R; Nair, Pallavi; Young, Elizabeth; Sofka, Carolyn; Deland, Jonathan T; Ellis, Scott J

    2013-02-01

    Successful correction of hindfoot alignment in adult acquired flatfoot deformity (AAFD) is likely influenced by the degree of medializing calcaneal osteotomy (MCO) performed, but it is not known if other reconstruction procedures significantly contribute as well. The purpose of this study was to evaluate the correlation between common preoperative and postoperative variables and hindfoot alignment. Thirty patients with stage II AAFD undergoing flatfoot reconstruction were followed prospectively. Preoperative and postoperative radiographs were reviewed to assess for correction in hindfoot alignment as measured by the change in hindfoot moment arm. Nineteen variables were analyzed, including age, gender, height, weight, body mass index (BMI), medial cuneiform-fifth metatarsal height, anteroposterior (AP) talonavicular coverage, AP talus-first metatarsal, lateral talus-first metatarsal and calcaneal pitch angles as well as intraoperative use of the MCO, lateral column lengthening (LCL), Cotton osteotomy, first tarsometatarsal fusion, flexor digitorum longus transfer, spring ligament reconstruction, and gastrocnemius recession or Achilles lengthening. Mean age was 57.3 years (range, 22-77). Final radiographs were obtained at a mean of 47 weeks (range, 25-78) postoperatively. Seven variables were found to significantly affect hindfoot moment arm. These were gender (P < .05), the amount of MCO performed (P < .001), LCL (P < .01), first tarsometatarsal fusion (P < .01), spring ligament reconstruction (P < .01), medial cuneiform-fifth metatarsal height (P < .001), and calcaneal pitch angle (P < .05). Multivariate regression analysis revealed that MCO was the only significant predictor of hindfoot moment arm. The final regression model for MCO showed a good fit (R(2) = .93, P < .001). Correction of hindfoot valgus alignment obtained in flatfoot reconstruction is primarily determined by the MCO procedure and can be modeled linearly. We believe that the hindfoot alignment view can serve as a valuable preoperative measurement to help surgeons adjust the proper amount of correction intraoperatively. Level IV, prospective case series.

  4. 3,3'-Diiodothyronine sulfate excretion in maternal urine reflects fetal thyroid function in sheep.

    PubMed

    Wu, S Y; Huang, W S; Fisher, D A; Florsheim, W H; Kashiwai, K; Polk, D H

    2001-09-01

    We have shown that there is significant fetal-to-maternal transfer of sulfated metabolites of thyroid hormone after fetal infusion of a pharmacologic amount of 3,3',5-triiodothyronine (T(3)) or sulfated T(3) in late pregnancy in sheep (Am J Physiol 277:E915, 1999). The transferred iodothyronine sulfoconjugate, i.e. 3,3'-diiodothyronine sulfate (T(2)S), of fetal origin appears in maternal sheep urine. The present study was carried out to assess the contribution of T(2)S of fetal origin to the urinary pool in ewes. Eighteen date-bred ewes (mean gestational age of 115 d) and their twin fetuses were divided into four groups. In group I (control, n = 5), both ewes (M) and their fetuses (F) were sham operated for thyroidectomy (Tx). In group II, the ewes (MTx, n = 4) and, in group III, the fetuses (FTx, n = 4) were subjected to Tx. In group IV (MTx.FTx, n = 5), both the ewe and fetus had Tx. After 10-12 d, fetal and/or maternal hypothyroidism were confirmed by serum thyroxine (<15 nmol/L) measurements. In addition, we infused radioactive T(3) without disturbing the T(3) pool in three singleton near-term fetuses and assessed the amount of radioactive iodothyronine that appeared in maternal urine (MU). After infusing [(125)I-3'],3,5-T(3) via fetal vein to the near-term normal fetuses, radioactive T(2)S was identified as the major metabolite in MU by HPLC and T(2)S-specific antibody. MU T(2)S excretion (pmol/mmol creatinine) was significantly reduced by FTx and MTx.FTx but not by MTx. In addition, positive correlations (p < 0.01) were found between MU T(2)S excretion and fetal serum thyroxine and T(3) concentrations but not with maternal serum thyroxine or T(3) levels. T(2)S of fetal origin contributes significantly to the MU pool.

  5. Quantitative analysis on sensitive factors of runoff change in Fenhe watershed based on integration approach

    NASA Astrophysics Data System (ADS)

    Wang, Deng; Jian, Shengqi; Wu, Zening; Zhang, Zhaoxi; Hu, Caihong

    2018-06-01

    The runoff of the Fenhe River flowed into the Yellow River (RRY) is reducing significantly due to the influence of climate change and human activities. It is generating bad situation of shortage of water resources and led to the deterioration of ecological environment of Shanxi Province. At the same time, the reduction in RRY causes the runoff reduction in Yellow River and exacerbated the water resources shortage of the middle area of the Yellow River. Therefore, it is important to alleviate water shortage and develop the soil and water conservation measurements and regional water policy by analyzing the influence of human activities and climate change on the RRY. The existing study quantified the reduction in amount of RRY which caused by human activities and climate change using statistical methods and watershed hydrological model. The main results of the study were as follow:

    1. Using hydrological variation diagnosis system, the variation characteristics of long time series of measured annual runoff were analyzed in Hejin station that is the Fenhe River control station. The results showed that the runoff of Fenhe River run into Yellow River declined year by year, in 1971, fell the most obviously.
    2. The impact of LUCC on runoff was calculated using the method of area ratio in the Fenhe River basin. Human activities were major factor in the reduction of RRY than the climate change, contributed 83.09 % of the total reduction in RRY, Groundwater exploitation gave the greatest contribution to the decrease in RRY in the scope of several kinds of human activity (30.09 %), followed by coal mining (26.03 %), climate changed contributed 19.17 % of the total reduction of RRY, and the decrease of precipitation contributed 20.81 %. But the variation of air temperature and wind speed would result in the increase of the amount of RRY.

  6. Gas analysis reveals novel aerobic deammonification in thermophilic aerobic digestion.

    PubMed

    Yi, Y S; Kim, S; An, S; Choi, S I; Choi, E; Yun, Z

    2003-01-01

    A laboratory-scale thermophilic aerobic digester was operated with piggery wastewater. The operating temperature varied from 50-70 degrees C. It has been found that excessive nitrogen removal occurred in the laboratory-scale thermophilic system at various HRTs. Nitrite and nitrate were not observed in the effluent. Gas measurement reveals the presence of significant amount of N2O along with NH3 gas. The rational production of N2O gas in accordance with temperature and HRT suggests that biologically mediated deammonification processes significantly contribute to the N removal. Although further microbiological investigation is required to clarify the exact nitrogen removal mechanism, the large production of N2O gas seems to be a result of the existence of a rapid growing heterotrophic deammonification process in the thermophilic system.

  7. Contribution of citrulline to the formation of ethyl carbamate during Chinese rice wine production.

    PubMed

    Wang, Peihong; Sun, Junyong; Li, Xiaomin; Wu, Dianhui; Li, Tong; Lu, Jian; Chen, Jian; Xie, Guangfa

    2014-04-01

    Ethyl carbamate is a well-known carcinogen and widely occurs in Chinese rice wine. To provide more clues to minimise ethyl carbamate accumulation, the levels of possible precursors of ethyl carbamate in Chinese rice wine were investigated by HPLC. Studies of the possible precursors of ethyl carbamate in Chinese raw rice wine with various additives and treatments indicated that significant amounts of urea can account for ethyl carbamate formation. It was also recognised that citrulline is another important precursor that significantly affects ethyl carbamate production during the boiling procedure used in the Chinese rice wine manufacturing process. Besides urea and citrulline, arginine was also found to be an indirect ethyl carbamate precursor due to its ability to form urea and citrulline by microorganism metabolism.

  8. A review of human factors causations in commercial air transport accidents and incidents: From to 2000-2016

    NASA Astrophysics Data System (ADS)

    Kharoufah, Husam; Murray, John; Baxter, Glenn; Wild, Graham

    2018-05-01

    Human factors have been defined by the International Civil Aviation Organization (ICAO) as "about people in their living and working situations; about their relationship with machines, with procedures and with the environment about them; and about their relationships with other people (at work)". Human factors contribute to approximately 75% of aircraft accidents and incidents. As such, understanding their influence is essential to improve safety in the aviation industry. This study examined the different human factors causations in a random sample of over 200 commercial air transport accidents and incidents from 2000 to 2016. The main objective of this study was to identify the principal human factor contributions to aviation accidents and incidents. An exploratory research design was utilised. The qualitative data were recorded in a database, and were coded into categories about the flights (including date, manufacturer, carrier, state of occurrence, etc). These categories were then analysed using Chi-Squared tests to determine which were statistically significant in terms of having an influence on the accidents/incidents. The most significant human factor was found to be situational awareness followed by non-adherence to procedures. In addition, charter operations proved to have a significantly higher rate of human factor related occurrence as compared to other type of operations. A significant finding was that Africa has a high rate of accidents/incidents relative to the amount of traffic and aircraft movements. These findings reflect some of the more noteworthy incidents that have received significant media attention, including Air Asia 8501 on the 28th of December 2014, TransAsia Airways 235 on the 4th of February 2015, and Air France 447 on the 1st of June 2009; these accidents resulted in a significant loss of lives where situational awareness and non-adherence to procedures were significant contributing factors.

  9. Primary sources of PM2.5 organic aerosol in an industrial Mediterranean city, Marseille

    NASA Astrophysics Data System (ADS)

    El Haddad, I.; Marchand, N.; Wortham, H.; Piot, C.; Besombes, J.-L.; Cozic, J.; Chauvel, C.; Armengaud, A.; Robin, D.; Jaffrezo, J.-L.

    2011-03-01

    Marseille, the most important port of the Mediterranean Sea, represents a challenging case study for source apportionment exercises, combining an active photochemistry and multiple emission sources, including fugitive emissions from industrial sources and shipping. This paper presents a Chemical Mass Balance (CMB) approach based on organic markers and metals to apportion the primary sources of organic aerosol in Marseille, with a special focus on industrial emissions. Overall, the CMB model accounts for the major primary anthropogenic sources including motor vehicles, biomass burning and the aggregate emissions from three industrial processes (heavy fuel oil combustion/shipping, coke production and steel manufacturing) as well as some primary biogenic emissions. This source apportionment exercise is well corroborated by 14C measurements. Primary OC estimated by the CMB accounts on average for 22% of total OC and is dominated by the vehicular emissions that contribute on average for 17% of OC mass concentration (vehicular PM contributes for 17% of PM2.5). Even though industrial emissions contribute only 2.3% of the total OC (7% of PM2.5), they are associated with ultrafine particles (Dp<80 nm) and high concentrations of Polycyclic Aromatic Hydrocarbons (PAH) and heavy metals such as Pb, Ni and V. On one hand, given that industrial emissions governed key primary markers, their omission would lead to substantial uncertainties in the CMB analysis performed in areas heavily impacted by such sources, hindering accurate estimation of non-industrial primary sources and secondary sources. On the other hand, being associated with bursts of submicron particles and carcinogenic and mutagenic components such as PAH, these emissions are most likely related with acute ill-health outcomes and should be regulated despite their small contributions to OC. Another important result is the fact that 78% of OC mass cannot be attributed to the major primary sources and, thus, remains un-apportioned. We have consequently critically investigated the uncertainties underlying our CMB apportionments. While we have provided some evidence for photochemical decay of hopanes, this decay does not appear to significantly alter the CMB estimates of the total primary OC. Sampling artifacts and unaccounted primary sources also appear to marginally influence the amount of un-apportioned OC. Therefore, this significant amount of un-apportioned OC is mostly attributed to secondary organic carbon that appears to be the major component of OC during the whole period of study.

  10. Predicting negative drinking consequences: examining descriptive norm perception.

    PubMed

    Benton, Stephen L; Downey, Ronald G; Glider, Peggy S; Benton, Sherry A; Shin, Kanghyun; Newton, Douglas W; Arck, William; Price, Amy

    2006-05-01

    This study explored how much variance in college student negative drinking consequences is explained by descriptive norm perception, beyond that accounted for by student gender and self-reported alcohol use. A derivation sample (N=7565; 54% women) and a replication sample (N=8924; 55.5% women) of undergraduate students completed the Campus Alcohol Survey in classroom settings. Hierarchical regression analyses revealed that student gender and average number of drinks when "partying" were significantly related to harmful consequences resulting from drinking. Men reported more consequences than did women, and drinking amounts were positively correlated with consequences. However, descriptive norm perception did not explain any additional variance beyond that attributed to gender and alcohol use. Furthermore, there was no significant three-way interaction among student gender, alcohol use, and descriptive norm perception. Norm perception contributed no significant variance in explaining harmful consequences beyond that explained by college student gender and alcohol use.

  11. Application of Taguchi L16 design method for comparative study of ability of 3A zeolite in removal of Rhodamine B and Malachite green from environmental water samples.

    PubMed

    Rahmani, Mashaallah; Kaykhaii, Massoud; Sasani, Mojtaba

    2018-01-05

    This study aimed to investigate the efficiency of 3A zeolite as a novel adsorbent for removal of Rhodamine B and Malachite green dyes from water samples. To increase the removal efficiency, effecting parameters on adsorption process were investigated and optimized by adopting Taguchi design of experiments approach. The percentage contribution of each parameter on the removal of Rhodamine B and Malachite green dyes determined using ANOVA and showed that the most effective parameters in removal of RhB and MG by 3A zeolite are initial concentration of dye and pH, respectively. Under optimized condition, the amount predicted by Taguchi design method and the value obtained experimentally, showed good closeness (more than 94.86%). Good adsorption efficiency obtained for proposed methods indicates that, the 3A zeolite is capable to remove the significant amounts of Rhodamine B and Malachite green from environmental water samples. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Alpha-A crystallin: quantitation of C-terminal modification during lens aging

    NASA Technical Reports Server (NTRS)

    Takemoto, L.; Gopalakrishnan, S.; Spooner, B. S. (Principal Investigator)

    1994-01-01

    Previous studies have demonstrated that the C-terminal region of alpha-A crystallin is susceptible to age-dependent, posttranslational modification. To quantitate the amount of modification, alpha-A crystallin was purified from total proteins of the aging bovine lens, then digested with lys-C endoproteinase. Reverse phase, high pressure liquid chromatography was used to resolve and quantitate the resulting peptides, to determine the amount of C-terminal peptide relative to peptides from other regions of the protein that have not been reported to undergo modification. The results indicate that relative to alpha-A crystallin from newborn lens, posttranslational modification has occurred in approximately 45-55% of the C-terminal region from mature lens. These results demonstrate extensive modification of the C-terminal region of alpha-A crystallin from the mature lens, indicating that during the aging process, posttranslational modifications in this region may make significant contributions to the aggregated state and/or molecular chaperone properties of the molecule.

  13. Application of Taguchi L16 design method for comparative study of ability of 3A zeolite in removal of Rhodamine B and Malachite green from environmental water samples

    NASA Astrophysics Data System (ADS)

    Rahmani, Mashaallah; Kaykhaii, Massoud; Sasani, Mojtaba

    2018-01-01

    This study aimed to investigate the efficiency of 3A zeolite as a novel adsorbent for removal of Rhodamine B and Malachite green dyes from water samples. To increase the removal efficiency, effecting parameters on adsorption process were investigated and optimized by adopting Taguchi design of experiments approach. The percentage contribution of each parameter on the removal of Rhodamine B and Malachite green dyes determined using ANOVA and showed that the most effective parameters in removal of RhB and MG by 3A zeolite are initial concentration of dye and pH, respectively. Under optimized condition, the amount predicted by Taguchi design method and the value obtained experimentally, showed good closeness (more than 94.86%). Good adsorption efficiency obtained for proposed methods indicates that, the 3A zeolite is capable to remove the significant amounts of Rhodamine B and Malachite green from environmental water samples.

  14. Effects of exposure to ultraviolet light on the development of Rana pipiens, the northern leopard frog

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, J.J.; Wofford, H.W.

    1996-10-01

    The increase in ultraviolet light intensity levels due to ozone depletion recently has been linked to the decline in amphibian population. In this experiment, eggs and larvae of Rana pipiens were subjected to differing amounts of ultraviolet radiation to determine the effects of ultraviolet light on the development of amphibian tadpoles. The total length, length of body without tail, and maximum width of each specimen was recorded for a month of the tadpoles` development, including several measurements after the ultraviolet exposures were concluded. It was found that ultraviolet exposure significantly reduced the size of the organisms in comparison with themore » control group in all three measured areas. Ultraviolet radiation altered the health and appearance of the exposed organisms and was lethal at large amounts. This experiment showed that ultraviolet radiation could cause many problems in developing amphibians. By slowing their development and physically weakening predation, thus contributing to a decline in overall population levels.« less

  15. Volatile inventory and early evolution of the planetary atmospheres

    NASA Astrophysics Data System (ADS)

    Marov, Mikhail Ya.; Ipatov, Sergei I.

    Formation of atmospheres of the inner planets involved the concurrent processes of mantle degassing and collisions that culminated during the heavy bombardment. Volatile-rich icy planetesimals impacting on the planets as a late veneer strongly contributed to the volatile inventory. Icy remnants of the outer planet accretion significantly complemented the accumulation of the lithophile and atmophile elements forced out onto the surface of the inner planets from silicate basaltic magma enriched in volatiles. Orbital dynamics of small bodies, including near-Earth asteroids, comets, and bodies from the Edgeworth-Kuiper belt evolving to become inner planet crossers, is addressed to examine different plausible amounts of volatile accretion. The relative importance of comets and chondrites in the delivery of volatiles is constrained by the observed fractionation pattern of noble gas abundances in the atmospheres of inner planets. The following development of the early atmospheres depended on the amount of volatiles expelled from the interiors and deposited by impactors, while the position of the planet relative to the Sun and its mass affected its climatic evolution.

  16. Clinical characteristics of vaginal discharge in bacterial vaginosis diagnosed by Nugent's criteria.

    PubMed

    Hapsari, E D; Hayashi, M; Matsuo, H

    2006-01-01

    To determine which clinical signs have an important contribution in bacterial vaginosis (BV) diagnosed by Nugent's criteria. This was a cross-sectional study of 58 women undergoing vaginal examination at Hayashi women's clinic, Hyogo Prefecture. Characteristics of vaginal discharge (color, amount, odor, and pH level) and the number of clue cells were compared among normal, intermediate, and BV groups. BV was diagnosed by using Nugent's criteria. The incidence of BV in our study population was 25.9%. Compared to the non-BV group, women in the BV group were found more often to have yellowish color and a moderate amount of discharge (66.67% vs 33.33%, NS; 55.56% vs 44.44%, NS), odorous discharge (100% vs 0%, p < 0.05) and furthermore, pH level and the number of clue cells were significantly higher. Odor, pH level and the number of clue cells in the vaginal discharge were helpful clinical signs for early detection of BV diagnosed by Nugent's criteria.

  17. Osmolarity as a contributing factor in topical drug delivery

    NASA Astrophysics Data System (ADS)

    Funke, Claire; Szeri, Andrew J.

    2017-11-01

    Gels and dissolvable solids are drug delivery platforms being evaluated for application of active pharmaceutical ingredients, termed microbicides, which act topically against infection by sexually transmitted HIV. In previous work, we have investigated how dilution by naturally produced fluid from the vaginal mucosa affects drug transport into the vaginal wall. We expand on this work by no longer assuming a constant flux and instead developing a relation for fluid transport based on osmolarity - thus allowing fluid to pass both into and out of epithelial cells. This relation shows that varying the osmolarity of the applied solution can have a significant effect on the amount of drug delivered to its target while holding the applied amount constant. This effect is modulated by a dimensionless group that relates the rates of solute and solvent transport. Ultimately, our goal is to develop a tool to understand better how to manipulate solution osmolarity in order to improve drug delivery within safety parameters for mucosal tissue.

  18. Trace metals in Bermuda rainwater

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jickells, T.D.; Knap, A.H.; Church, T.M.

    1984-02-20

    The concentration of Cd, Cu, Fe, Mn, Ni, Pb, and Zn have been measured in Bermuda rainwater. Factor analysis indicates that Fe, Mn, and Pb have similar to acidic components derived from North America. The other metals all behave simiarly but differently to the acides. Sea salt, even after allowances for fractionation, apparently contributes minor amounts of Cu, Pb, and Zn and uncertain amounts of Fe, Mn, and Cd to Atlantic Ocean precipitation. Wash out ratios, calculated from this data along with earlier measurements of atmospheric trace metal concentration on Bermuda, are of the same order as those reported frommore » other remote ocean areas. The wet depositional fluxes of Cu, Ni, Pb, and Zn to the western Atlantic Ocean are significant compared to measured oceanic flux rates. However, the wet depositional fluxes of Fe and Mn to this area are relatively small, suggesting additional inputs, while an excess wet depositional flux of Cd suggests large-scale atmospheric recycling of this element.« less

  19. 20 CFR Appendix Vii to Subpart C... - “Old-Law” Contribution and Benefit Base

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Appendix VII to Subpart C of Part 404 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Computing Primary Insurance Amounts Pt. 404, Subpt. C, App. VII... Security Act without the enactment of the 1977 amendments. Year Amount 1979 $18,900 1980 20,400 1981 22,200...

  20. Evaluating White Space of a Malaysian Secondary ELT Textbook

    ERIC Educational Resources Information Center

    Jin, Ng Yu

    2010-01-01

    Students are believed to learn at optimum level with materials with a lot of white space since the existence of vast number of words and limited amount of white space, especially in textbooks may contribute to the increase in anxiety among learners (Tomlinson, 1998). This study evaluates the amount of white space in terms of pixels in the…

  1. Discarding the Throwaway Society. Worldwatch Paper 101.

    ERIC Educational Resources Information Center

    Young, John E.

    Today's industrial economies were founded on the use of vast quantities of materials and energy, and the economic health of nations has often been equated with the amount they consumed. The amount of materials that originally enters an economy tells nothing about the material's eventual fate or its contribution to human well-being. It tells a good…

  2. Financial Audit: Congressional Award Foundation’s Fiscal Year 2000 and 1999 Financial Statements

    DTIC Science & Technology

    2001-05-01

    organizations. Assets and services contributed to the Foundation are recorded in the accounting records at fair value as of the date of the...records as contributions revenue amounts received in the form of cash, promises or pledges to give, and the fair value of certain contributed services and...or, as described in note 2A, at fair value at the date of contribution. Fixed assets such as office furniture valued in excess of $500 are

  3. 24 CFR 115.304 - Agencies eligible for contributions funds.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... Contributions funding consists of five categories: (1) Complaint processing (CP) funds; (2) Special enforcement...) funds; and (5) Partnership (P) funds. (b) CP funds. (1) Agencies receiving CP funds will receive such... percent of the agency's total FHAP payment amount for the preceding year, in addition to CP funds...

  4. 24 CFR 115.304 - Agencies eligible for contributions funds.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... Contributions funding consists of five categories: (1) Complaint processing (CP) funds; (2) Special enforcement...) funds; and (5) Partnership (P) funds. (b) CP funds. (1) Agencies receiving CP funds will receive such... percent of the agency's total FHAP payment amount for the preceding year, in addition to CP funds...

  5. 24 CFR 115.304 - Agencies eligible for contributions funds.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... Contributions funding consists of five categories: (1) Complaint processing (CP) funds; (2) Special enforcement...) funds; and (5) Partnership (P) funds. (b) CP funds. (1) Agencies receiving CP funds will receive such... percent of the agency's total FHAP payment amount for the preceding year, in addition to CP funds...

  6. 24 CFR 115.304 - Agencies eligible for contributions funds.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... Contributions funding consists of five categories: (1) Complaint processing (CP) funds; (2) Special enforcement...) funds; and (5) Partnership (P) funds. (b) CP funds. (1) Agencies receiving CP funds will receive such... percent of the agency's total FHAP payment amount for the preceding year, in addition to CP funds...

  7. 24 CFR 115.304 - Agencies eligible for contributions funds.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... Contributions funding consists of five categories: (1) Complaint processing (CP) funds; (2) Special enforcement...) funds; and (5) Partnership (P) funds. (b) CP funds. (1) Agencies receiving CP funds will receive such... percent of the agency's total FHAP payment amount for the preceding year, in addition to CP funds...

  8. The contribution of school meals and packed lunch to food consumption and nutrient intakes in UK primary school children from a low income population.

    PubMed

    Stevens, L; Nelson, M

    2011-06-01

    The Low Income Diet and Nutrition Survey described the food consumption and nutrient intake of UK children in low income households in 2003-2005. To describe food consumption and nutrient intake associated with school meals and packed lunches, based on a cross-sectional analysis of 680, 24-h dietary recalls from 311 school children aged 4-11 years. In children from low income households, pupils who took a packed lunch consumed more white bread, fats and oils, crisps and confectionery and fewer potatoes (cooked with or without fat) at lunchtime compared to other pupils. Many of these differences persisted when diet was assessed over the day. For younger pupils (4-7 years), packed lunches provided the least amount of folate, the highest amount of sodium, and the highest average percentage of food energy from fat and saturated fatty acids (SFA) compared to free school meals (FSMs). Over the whole day, in both younger (4-7 years) and older (8-11 years) children, there were no notable differences in energy or nutrient intake between those eating a packed lunch or a school meal. Older children's packed lunches contributed a significantly higher proportion of fat, SFA, calcium and sodium to the day's nutrient intake compared to a FSM. In children from low income households, packed lunches are less likely to contribute towards a 'healthier' diet compared to a school meal. The difference was more apparent in younger children. Key differences were the high consumption of sodium, SFA and non-milk extrinsic sugars by pupils who had packed lunches. © 2011 The Authors. Journal compilation © 2011 The British Dietetic Association Ltd.

  9. Characterization of large-pore polymeric supports for use in perfusion biochromatography.

    PubMed

    Whitney, D; McCoy, M; Gordon, N; Afeyan, N

    1998-05-22

    Perfusion chromatography is uniquely characterized by the flow of a portion of the column eluent directly through the resin in the packed bed. The benefits of this phenomenon and some of the properties of perfusive resins have been described before, and can be summarized as enhanced mass transport to interior binding sites. Here we extend the understanding of this phenomenon by comparing resins with different pore size distributions. Resins are chosen to give approximately the same specific pore volumes (as shown in the characterization section) but the varying contribution of large pores is used to control the amount of liquid flowing through the beads. POROS R1 has the largest contribution of throughpores, and therefore the greatest intraparticle flow. POROS R2 has a lower contribution of throughpores, and a higher surface area coming from a greater population of diffusive pores, but still shows significant mass transport enhancements relative to a purely diffusive control. Oligo R3 is dominated by a high population of diffusive pores, and is used comparatively as a non-perfusive resin. Although the pore size distribution can be engineered to control mass transport rates, the resulting surface area is not the only means by which binding capacity can be controlled. Surface coatings are employed to increase binding capacity without fundamentally altering the mass transport properties. Models are used to describe the amount of flow transecting the beads, and comparisons of coated resins to uncoated (polystyrene) resins leads to the conclusion that these coatings do not obstruct the throughpore structures. This is an important conclusion since the binding capacity of the coated product, in some cases, is shown to be over 10-fold higher than the precursor polystyrene scaffold (i.e., POROS R1 or POROS R2).

  10. Uncovering the Recycling Potential of "New" WEEE in China.

    PubMed

    Zeng, Xianlai; Gong, Ruying; Chen, Wei-Qiang; Li, Jinhui

    2016-02-02

    Newly defined categories of WEEE have increased the types of China's regulated WEEE from 5 to 14. Identification of the amounts and valuable-resource components of the "new" WEEE generated is critical to solving the e-waste problem, for both governmental policy decisions and recycling enterprise expansions. This study first estimates and predicts China's new WEEE generation for the period of 2010-2030 using material flow analysis and the lifespan model of the Weibull distribution, then determines the amounts of valuable resources (e.g., base materials, precious metals, and rare-earth minerals) encased annually in WEEE, and their dynamic transfer from in-use stock to waste. Main findings include the following: (i) China will generate 15.5 and 28.4 million tons WEEE in 2020 and 2030, respectively, and has already overtaken the U.S. to become the world's leading producer of e-waste; (ii) among all the types of WEEE, air conditioners, desktop personal computers, refrigerators, and washing machines contribute over 70% of total WEEE by weight. The two categories of EEE-electronic devices and electrical appliances-each contribute about half of total WEEE by weight; (iii) more and more valuable resources have been transferred from in-use products to WEEE, significantly enhancing the recycling potential of WEEE from an economic perspective; and (iv) WEEE recycling potential has been evolving from ∼16 (10-22) billion US$ in 2010, to an anticipated ∼42 (26-58) billion US$ in 2020 and ∼73.4 (44.5-103.4) billion US$ by 2030. All the obtained results can improve the knowledge base for closing the loop of WEEE recycling, and contribute to governmental policy making and the recycling industry's business development.

  11. Extracellular ammonia at sites of pulmonary infection with Coccidioides posadasii contributes to severity of the respiratory disease.

    PubMed

    Wise, Hua Zhang; Hung, Chiung-Yu; Whiston, Emily; Taylor, John W; Cole, Garry T

    2013-01-01

    Coccidioides is the causative agent of a potentially life-threatening respiratory disease of humans. A feature of this mycosis is that pH measurements of the microenvironment of pulmonary abscesses are consistently alkaline due to ammonia production during the parasitic cycle. We previously showed that enzymatically active urease is partly responsible for elevated concentrations of extracellular ammonia at sites of lung infection and contributes to both localized host tissue damage and exacerbation of the respiratory disease in BALB/c mice. Disruption of the urease gene (URE) of Coccidioides posadasii only partially reduced the amount of ammonia detected during in vitro growth of the parasitic phase, suggesting that other ammonia-producing pathways exist that may also contribute to the virulence of this pathogen. Ureidoglycolate hydrolase (Ugh) expressed by bacteria, fungi and higher plants catalyzes the hydrolysis of ureidoglycolate to yield glyoxylate and the release CO2 and ammonia. This enzymatic pathway is absent in mice and humans. Ureidoglycolate hydrolase gene deletions were conducted in a wild type (WT) isolate of C. posadasii as well as the previously generated Δure knock-out strain. Restorations of UGH in the mutant stains were performed to generate and evaluate the respective revertants. The double mutant revealed a marked decrease in the amount of extracellular ammonia without loss of reproductive competence in vitro compared to both the WT and Δure parental strains. BALB/c mice challenged intranasally with the Δugh/Δure mutant showed 90% survival after 30 days, decreased fungal burden, and well-organized pulmonary granulomas. We conclude that loss of both Ugh and Ure activity significantly reduced the virulence of this fungal pathogen. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deason, Alis J.; Mao, Yao-Yuan; Wechsler, Risa H.

    In this paper, we study the mass spectrum of destroyed dwarfs that contribute to the accreted stellar mass of Milky Way (MW)-mass (M vir ~ 10 12.1 M ⊙) halos using a suite of 45 zoom-in dissipationless simulations. Empirical models are employed to relate (peak) subhalo mass to dwarf stellar mass, and we use constraints from z = 0 observations and hydrodynamical simulations to estimate the metallicity distribution of the accreted stellar material. The dominant contributors to the accreted stellar mass are relatively massive dwarfs with M star ~ 10 8–10 10M ⊙. Halos with more quiescent accretion histories tendmore » to have lower mass progenitors (10 8–10 9 M ⊙), and lower overall accreted stellar masses. Ultra-faint mass (M star < 10 5 M ⊙) dwarfs contribute a negligible amount (<<1%) to the accreted stellar mass and, despite having low average metallicities, supply a small fraction (~2%–5%) of the very metal-poor stars with [Fe/H] < -2. Dwarfs with masses 10 5 < M star/M ⊙ < 10 8 provide a substantial amount of the very metal-poor stellar material (~40%–80%), and even relatively metal-rich dwarfs with M star > 10 8 M ⊙ can contribute a considerable fraction (~20%–60%) of metal-poor stars if their metallicity distributions have significant metal-poor tails. Finally, we find that the generic assumption of a quiescent assembly history for the MW halo seems to be in tension with the mass spectrum of its surviving dwarfs. In conclusion, we suggest that the MW could be a "transient fossil"; a quiescent halo with a recent accretion event(s) that disguises the preceding formation history of the halo.« less

  13. Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia.

    PubMed

    Chen, Yongqiang; Henson, Elizabeth S; Xiao, Wenyan; Huang, Daniel; McMillan-Ward, Eileen M; Israels, Sara J; Gibson, Spencer B

    2016-06-02

    Autophagy is an intracellular lysosomal degradation pathway where its primary function is to allow cells to survive under stressful conditions. Autophagy is, however, a double-edge sword that can either promote cell survival or cell death. In cancer, hypoxic regions contribute to poor prognosis due to the ability of cancer cells to adapt to hypoxia in part through autophagy. In contrast, autophagy could contribute to hypoxia induced cell death in cancer cells. In this study, we showed that autophagy increased during hypoxia. At 4 h of hypoxia, autophagy promoted cell survival whereas, after 48 h of hypoxia, autophagy increased cell death. Furthermore, we found that the tyrosine phosphorylation of EGFR (epidermal growth factor receptor) decreased after 16 h in hypoxia. Furthermore, EGFR binding to BECN1 in hypoxia was significantly higher at 4 h compared to 72 h. Knocking down or inhibiting EGFR resulted in an increase in autophagy contributing to increased cell death under hypoxia. In contrast, when EGFR was reactivated by the addition of EGF, the level of autophagy was reduced which led to decreased cell death. Hypoxia led to autophagic degradation of the lipid raft protein CAV1 (caveolin 1) that is known to bind and activate EGFR in a ligand-independent manner during hypoxia. By knocking down CAV1, the amount of EGFR phosphorylation was decreased in hypoxia and amount of autophagy and cell death increased. This indicates that the activation of EGFR plays a critical role in the switch between cell survival and cell death induced by autophagy in hypoxia.

  14. The Eating Habits of Milky Way Mass Halos: Destroyed Dwarf Satellites and the Metallicity Distribution of Accreted Stars

    DOE PAGES

    Deason, Alis J.; Mao, Yao-Yuan; Wechsler, Risa H.

    2016-04-01

    In this paper, we study the mass spectrum of destroyed dwarfs that contribute to the accreted stellar mass of Milky Way (MW)-mass (M vir ~ 10 12.1 M ⊙) halos using a suite of 45 zoom-in dissipationless simulations. Empirical models are employed to relate (peak) subhalo mass to dwarf stellar mass, and we use constraints from z = 0 observations and hydrodynamical simulations to estimate the metallicity distribution of the accreted stellar material. The dominant contributors to the accreted stellar mass are relatively massive dwarfs with M star ~ 10 8–10 10M ⊙. Halos with more quiescent accretion histories tendmore » to have lower mass progenitors (10 8–10 9 M ⊙), and lower overall accreted stellar masses. Ultra-faint mass (M star < 10 5 M ⊙) dwarfs contribute a negligible amount (<<1%) to the accreted stellar mass and, despite having low average metallicities, supply a small fraction (~2%–5%) of the very metal-poor stars with [Fe/H] < -2. Dwarfs with masses 10 5 < M star/M ⊙ < 10 8 provide a substantial amount of the very metal-poor stellar material (~40%–80%), and even relatively metal-rich dwarfs with M star > 10 8 M ⊙ can contribute a considerable fraction (~20%–60%) of metal-poor stars if their metallicity distributions have significant metal-poor tails. Finally, we find that the generic assumption of a quiescent assembly history for the MW halo seems to be in tension with the mass spectrum of its surviving dwarfs. In conclusion, we suggest that the MW could be a "transient fossil"; a quiescent halo with a recent accretion event(s) that disguises the preceding formation history of the halo.« less

  15. Adiponectin in Fresh Frozen Plasma Contributes to Restoration of Vascular Barrier Function after Hemorrhagic Shock

    PubMed Central

    Huby, Maria P.; Duan, Chaojun; Baer, Lisa; Peng, Zhanglong; Kozar, Rosemary A.; Doursout, Marie-Francoise; Holcomb, John B.; Wade, Charles E.; Ko, Tien C.

    2015-01-01

    Hemorrhagic shock is the leading cause of preventable deaths in civilian and military trauma. Use of fresh frozen plasma (FFP) in patients requiring massive transfusion is associated with improved outcomes. FFP contains significant amounts of adiponectin, which is known to have vascular protective function. We hypothesize that FFP improves vascular barrier function largely via adiponectin. Plasma adiponectin levels were measured in 19 severely injured patients in hemorrhagic shock (HS). Compared to normal individuals, plasma adiponectin levels decreased to 49% in HS patients prior to resuscitation (p<0.05) and increased to 64% post resuscitation (but not significant). In a HS mouse model, we demonstrated a similar decrease in plasma adiponectin to 54% but a significant increase to 79% by FFP resuscitation compared to baseline (p<0.05). HS disrupted lung vascular barrier function, leading to an increase in permeability. FFP resuscitation reversed these HS-induced effects. Immunodepletion of adiponectin from FFP abolished FFP's effects on blocking endothelial hyperpermeability in vitro, and on improving lung vascular barrier function in HS mice. Replenishment with adiponectin rescued FFP's effects. These findings suggest that adiponectin is an important component in FFP resuscitation contributing to the beneficial effects on vascular barrier function after HS. PMID:26263440

  16. African American English-speaking students: an examination of the relationship between dialect shifting and reading outcomes.

    PubMed

    Craig, Holly K; Zhang, Lingling; Hensel, Stephanie L; Quinn, Erin J

    2009-08-01

    In this study, the authors evaluated the contribution made by dialect shifting to reading achievement test scores of African American English (AAE)-speaking students when controlling for the effects of socioeconomic status (SES), general oral language abilities, and writing skills. Participants were 165 typically developing African American 1st through 5th graders. Half were male and half were female, one third were from low-SES homes, and two-thirds were from middle-SES homes. Dialect shifting away from AAE toward Standard American English (SAE) was determined by comparing AAE production rates during oral and written narratives. Structural equation modeling evaluated the relative contributions of AAE rates, SES, and general oral language and writing skills on standardized reading achievement scores. AAE production rates were inversely related to reading achievement scores and decreased significantly between the oral and written narratives. Lower rates in writing predicted a substantial amount of the variance in reading scores, showing a significant direct effect and a significant indirect effect mediated by measures of oral language comprehension. The findings support a dialect shifting-reading achievement hypothesis, which proposes that AAE-speaking students who learn to use SAE in literacy tasks will outperform their peers who do not make this linguistic adaptation.

  17. Stromal laminin chain distribution in normal, hyperplastic and malignant oral mucosa: relation to myofibroblast occurrence and vessel formation.

    PubMed

    Franz, Marcus; Wolheim, Anke; Richter, Petra; Umbreit, Claudia; Dahse, Regine; Driemel, Oliver; Hyckel, Peter; Virtanen, Ismo; Kosmehl, Hartwig; Berndt, Alexander

    2010-04-01

    The contribution of stromal laminin chain expression to malignant potential, tumour stroma reorganization and vessel formation in oral squamous cell carcinoma (OSCC) is not fully understood. Therefore, the expression of the laminin chains alpha2, alpha3, alpha4, alpha5 and gamma2 in the stromal compartment/vascular structures in OSCC was analysed. Frozen tissue of OSCC (9x G1, 24x G2, 8x G3) and normal (2x)/hyperplastic (11x) oral mucosa was subjected to laminin chain and alpha-smooth muscle actin (ASMA) immunohistochemistry. Results were correlated to tumour grade. The relation of laminin chain positive vessels to total vessel number was assessed by immunofluorescence double labelling with CD31. Stromal laminin alpha2 chain significantly decreases and alpha3, alpha4, alpha5 and gamma2 chains and also ASMA significantly increase with rising grade. The amount of stromal alpha3, alpha4 and gamma2 chains significantly increased with rising ASMA positivity. There is a significant decrease in alpha3 chain positive vessels with neoplastic transformation. Mediated by myofibroblasts, OSCC development is associated with a stromal up-regulation of laminin isoforms possibly contributing to a migration promoting microenvironment. A vascular basement membrane reorganization concerning alpha3 and gamma2 chain laminins during tumour angioneogenesis is suggested.

  18. Risk factors associated with open gingival embrasures after orthodontic treatment.

    PubMed

    An, Sang Su; Choi, Yoon Jeong; Kim, Ji Young; Chung, Chooryung J; Kim, Kyung-Ho

    2018-05-01

    To investigate the incidence of and contributing factors to open gingival embrasures between the central incisors after orthodontic treatment. One hundred posttreatment patients (29 men and 71 women; mean age, 24.7 years) were divided retrospectively into occurrence and nonoccurrence groups based on intraoral photographs. Based on the severity, the occurrence group was further divided into mild, moderate, and severe groups. Parameters from periapical radiographs, superimposed lateral cephalograms, and study models were compared between the occurrence and the nonoccurrence groups by using independent t-tests and were also analyzed on the basis of severity via analysis of variance. Logistic regression analysis was performed to identify the contributing factors to open gingival embrasures. The incidence of open gingival embrasures between the central incisors was 22% and 36% in the maxilla and the mandible, respectively. Lingual movement of the incisors, distance from the contact point to the alveolar crest after treatment, antero-posterior overlap of the two central incisors before treatment in the maxilla, and distance from the contact point to the alveolar crest after treatment in the mandible were significantly associated with the occurrence of open gingival embrasures ( P < .05). In the mandible, the amount of intrusion was significantly related to severity ( P < .05). The incidence of open gingival embrasures following orthodontic tooth movement is high. Therefore, attention should be paid to the contributing factors to prevent or reduce the occurrence of open gingival embrasures.

  19. Vertebral body bone strength: the contribution of individual trabecular element morphology.

    PubMed

    Parkinson, I H; Badiei, A; Stauber, M; Codrington, J; Müller, R; Fazzalari, N L

    2012-07-01

    Although the amount of bone explains the largest amount of variability in bone strength, there is still a significant proportion unaccounted for. The morphology of individual bone trabeculae explains a further proportion of the variability in bone strength and bone elements that contribute to bone strength depending on the direction of loading. Micro-CT imaging enables measurement of bone microarchitecture and subsequently mechanical strength of the same sample. It is possible using micro-CT data to perform morphometric analysis on individual rod and plate bone trabeculae using a volumetric spatial decomposition algorithm and hence determine their contribution to bone strength. Twelve pairs of vertebral bodies (T12/L1 or L4/L5) were harvested from human cadavers, and bone cubes (10 × 10 × 10 mm) were obtained. After micro-CT imaging, a volumetric spatial decomposition algorithm was applied, and measures of individual trabecular elements were obtained. Bone strength was measured in compression, where one bone specimen from each vertebral segment was tested supero-inferiorly (SI) and the paired specimen was tested antero-posteriorly (AP). Bone volume fraction was the strongest individual determinant of SI strength (r(2) = 0.77, p < 0.0001) and AP (r(2) = 0.54, p < 0.0001). The determination of SI strength was improved to r(2) = 0.87 with the addition of mean rod length and relative plate bone volume fraction. The determination of AP strength was improved to r(2) = 0.85 with the addition of mean rod volume and relative rod bone volume fraction. Microarchitectural measures of individual trabeculae that contribute to bone strength have been identified. In addition to the contribution of BV/TV, trabecular rod morphology increased the determination of AP strength by 57%, whereas measures of trabecular plate and rod morphology increased determination of SI strength by 13%. Decomposing vertebral body bone architecture into its constituent morphological elements shows that trabecular element morphology has specific functional roles to assist in maintaining skeletal integrity.

  20. Online production validation in a HEP environment

    NASA Astrophysics Data System (ADS)

    Harenberg, T.; Kuhl, T.; Lang, N.; Mättig, P.; Sandhoff, M.; Schwanenberger, C.; Volkmer, F.

    2017-03-01

    In high energy physics (HEP) event simulations, petabytes of data are processed and stored requiring millions of CPU-years. This enormous demand for computing resources is handled by centers distributed worldwide, which form part of the LHC computing grid. The consumption of such an important amount of resources demands for an efficient production of simulation and for the early detection of potential errors. In this article we present a new monitoring framework for grid environments, which polls a measure of data quality during job execution. This online monitoring facilitates the early detection of configuration errors (specially in simulation parameters), and may thus contribute to significant savings in computing resources.

  1. Parallel performance of TORT on the CRAY J90: Model and measurement

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barnett, A.; Azmy, Y.Y.

    1997-10-01

    A limitation on the parallel performance of TORT on the CRAY J90 is the amount of extra work introduced by the multitasking algorithm itself. The extra work beyond that of the serial version of the code, called overhead, arises from the synchronization of the parallel tasks and the accumulation of results by the master task. The goal of recent updates to TORT was to reduce the time consumed by these activities. To help understand which components of the multitasking algorithm contribute significantly to the overhead, a parallel performance model was constructed and compared to measurements of actual timings of themore » code.« less

  2. Review of amateur meteor research

    NASA Astrophysics Data System (ADS)

    Rendtel, Jürgen

    2017-09-01

    Significant amounts of meteor astronomical data are provided by amateurs worldwide, using various methods. This review concentrates on optical data. Long-term meteor shower analyses based on consistent data are possible over decades (Orionids, Geminids, κ-Cygnids) and allow combination with modelling results. Small and weak structures related to individual stream filaments of cometary dust have been analysed in both major and minor showers (Quadrantids, September ε-Perseids), providing feedback to meteoroid ejection and stream evolution processes. Meteoroid orbit determination from video meteor networks contributes to the improvement of the IAU meteor data base. Professional-amateur cooperation also concerns observations and detailed analysis of fireball data, including meteorite ground searches.

  3. An Approach for Removing Redundant Data from RFID Data Streams

    PubMed Central

    Mahdin, Hairulnizam; Abawajy, Jemal

    2011-01-01

    Radio frequency identification (RFID) systems are emerging as the primary object identification mechanism, especially in supply chain management. However, RFID naturally generates a large amount of duplicate readings. Removing these duplicates from the RFID data stream is paramount as it does not contribute new information to the system and wastes system resources. Existing approaches to deal with this problem cannot fulfill the real time demands to process the massive RFID data stream. We propose a data filtering approach that efficiently detects and removes duplicate readings from RFID data streams. Experimental results show that the proposed approach offers a significant improvement as compared to the existing approaches. PMID:22163730

  4. An Energy Dispersive X-ray Spectroscopy Analysis of Elemental Changes of a Persimmon Phytobezoar Dissolved in Coca-Cola.

    PubMed

    Iwamuro, Masaya; Urata, Haruo; Higashi, Reiji; Nakagawa, Masahiro; Ishikawa, Shin; Shiraha, Hidenori; Okada, Hiroyuki

    To investigate the mechanism of phytobezoar dissolution by Coca-Cola(®), persimmon phytobezoar pieces removed from a 60-year-old Japanese woman were analyzed by energy dispersive X-ray spectroscopy. The amount of calcium significantly decreased after dissolution treatment using Coca-Cola(®), suggesting a potential contribution of calcium to dissolution mechanisms. Moreover, immersion in Coca-Cola(®) for 120 hours on the exterior surface revealed that Coca-Cola(®) did not permeate persimmon phytobezoars. This is the first study to investigate the mechanisms of persimmon phytobezoar permeability and dissolution induced by Coca-Cola(®).

  5. A Comprehensive Computer Package for Ambulatory Surgical Facilities

    PubMed Central

    Kessler, Robert R.

    1980-01-01

    Ambulatory surgical centers are a cost effective alternative to hospital surgery. Their increasing popularity has contributed to heavy case loads, an accumulation of vast amounts of medical and financial data and economic pressures to maintain a tight control over “cash flow”. Computerization is now a necessity to aid ambulatory surgical centers to maintain their competitive edge. An on-line system is especially necessary as it allows interactive scheduling of surgical cases, immediate access to financial data and rapid gathering of medical and statistical information. This paper describes the significant features of the computer package in use at the Salt Lake Surgical Center, which processes 500 cases per month.

  6. Factors predicting desired autonomy in medical decisions: Risk-taking and gambling behaviors

    PubMed Central

    Fortune, Erica E; Shotwell, Jessica J; Buccellato, Kiara; Moran, Erin

    2016-01-01

    This study investigated factors that influence patients’ desired level of autonomy in medical decisions. Analyses included previously supported demographic variables in addition to risk-taking and gambling behaviors, which exhibit a strong relationship with overall health and decision-making, but have not been investigated in conjunction with medical autonomy. Participants (N = 203) completed measures on Amazon’s Mechanical Turk, including two measures of autonomy. Two hierarchical regressions revealed that the predictors explained a significant amount of variance for both measures, but the contribution of predictor variables was incongruent between models. Possible causes for this incongruence and implications for patient–physician interactions are discussed. PMID:28070406

  7. An Application of Multiplier Analysis in Analyzing the Role of Mining Sectors on Indonesian National Economy

    NASA Astrophysics Data System (ADS)

    Subanti, S.; Hakim, A. R.; Hakim, I. M.

    2018-03-01

    This purpose of the current study aims is to analyze the multiplier analysis on mining sector in Indonesia. The mining sectors defined by coal and metal; crude oil, natural gas, and geothermal; and other mining and quarrying. The multiplier analysis based from input output analysis, this divided by income multiplier and output multiplier. This results show that (1) Indonesian mining sectors ranked 6th with contribute amount of 6.81% on national total output; (2) Based on total gross value added, this sector contribute amount of 12.13% or ranked 4th; (3) The value from income multiplier is 0.7062 and the value from output multiplier is 1.2426.

  8. Efficient transport of tropospheric aerosol into the stratosphere via the Asian summer monsoon anticyclone

    NASA Astrophysics Data System (ADS)

    Yu, Pengfei; Rosenlof, Karen H.; Liu, Shang; Telg, Hagen; Thornberry, Troy D.; Rollins, Andrew W.; Portmann, Robert W.; Bai, Zhixuan; Ray, Eric A.; Duan, Yunjun; Pan, Laura L.; Toon, Owen B.; Bian, Jianchun; Gao, Ru-Shan

    2017-07-01

    An enhanced aerosol layer near the tropopause over Asia during the June-September period of the Asian summer monsoon (ASM) was recently identified using satellite observations. Its sources and climate impact are presently not well-characterized. To improve understanding of this phenomenon, we made in situ aerosol measurements during summer 2015 from Kunming, China, then followed with a modeling study to assess the global significance. The in situ measurements revealed a robust enhancement in aerosol concentration that extended up to 2 km above the tropopause. A climate model simulation demonstrates that the abundant anthropogenic aerosol precursor emissions from Asia coupled with rapid vertical transport associated with monsoon convection leads to significant particle formation in the upper troposphere within the ASM anticyclone. These particles subsequently spread throughout the entire Northern Hemispheric (NH) lower stratosphere and contribute significantly (˜15%) to the NH stratospheric column aerosol surface area on an annual basis. This contribution is comparable to that from the sum of small volcanic eruptions in the period between 2000 and 2015. Although the ASM contribution is smaller than that from tropical upwelling (˜35%), we find that this region is about three times as efficient per unit area and time in populating the NH stratosphere with aerosol. With a substantial amount of organic and sulfur emissions in Asia, the ASM anticyclone serves as an efficient smokestack venting aerosols to the upper troposphere and lower stratosphere. As economic growth continues in Asia, the relative importance of Asian emissions to stratospheric aerosol is likely to increase.

  9. NMR spectroscopic study of the carbon and nitrogen dynamics of grass-derived pyrogenic organic material during 2.3 years of incubation in soil

    NASA Astrophysics Data System (ADS)

    Hilscher, André; Knicker, Heike

    2010-05-01

    Incomplete combustion of vegetation results in pyrogenic organic material (PyOM) which occurs ubiquitously in soils and sediments. To understand the C sequestration potential of PyOM in environmental systems knowledge is required about the respective degradation and humification mechanisms and the stability of the different chemical PyOM structures. The present study focuses on the microbial recalcitrance of PyOM on molecular scale. Therefore, microcosms incubation experiments were performed using PyOM produced from highly isotopically enriched 13C and 15N rye grass (Lolium perenne) at 350°C under oxic conditions for one (1M) and four minutes (4M). Solid-state CPMAS 13C and 15N NMR studies were accomplished to obtain insights into the involved humification mechanisms at different stages the PyOM degradation. In total up to 38% of the bulk PyOM C was mineralised during the 28 months of incubation. The O/N-alkyl C and alkyl C residues which survived the charring process were effectively decomposed. At the end of the incubation up to 73% and 57% of the initial O/N-alkyl C and alkyl C amount were mineralised or converted to other C groups, respectively. The total aryl C group recovery of the PyOM decreased significantly during the 28 months of incubation (P ≤ 0.001). After 20 months of incubation between 26% and 40% of the initial aryl C amount was lost. For this group, relative short half time periods in the range of 3.0 and 3.8 years were obtained. The observed loss of aromatic C structures may be attributed to two simultaneous processes, the mineralisation to CO2 and the conversion to other C groups by partial oxidation. The presence of a readily decomposable co-substrate showed no significant changes in the degradation pattern of the different PyOM, possibly because decomposable sources were already available in the starting PyOM. Most of the organic bound N of the fresh PyOM was assignable to heterocyclic aromatic compounds such as pyrrole and indole-like structures with contributions of 62% and 72% for PyOM 1M and PyOM 4M, respectively. The other part of the 15N NMR signal intensity was assignable to amide-like structures. No major alteration of the amide and heterocyclic N contribution was detected for the PyOM 1M incubates. For the more charred PyOM 4M, the relative heterocyclic N contribution decreased. After the 28 months of incubation no significant difference in the chemical N composition of PyOM 4M related to the PyOM 1M treatments could be observed (P=0.472). Further, we detect a continuous degrease of the total amounts for the amide and heterocyclic N compounds. After 20 months, only 49% to 59% of the heterocyclic N compounds were recovered. The respective amide N recoveries were larger with 59% to 87%. It can be concluded, that PyOM may not be as highly refractory as it is commonly assumed. During the efficient degradation not only a considerable PyOM amount is mineralised, but also the chemical structure of the remaining PyOM is strongly modified. This includes the formation of O-containing functional groups and the loss of aromatic C and N containing heterocyclic domains by mineralisation and conversion to other C and N groups.

  10. [Effects of irrigation amount and stage on water consumption characteristics and grain yield of wheat].

    PubMed

    Wang, De-Mei; Yu, Zhen-Wen

    2008-09-01

    Field experiment was conducted in 2005 -2007 to study the effects of irrigation amount and stage on the water consumption characteristics, grain yield, and water use efficiency of wheat. The results showed that the variation coefficient of the proportion of soil water consumption amount to total water consumption amount was significantly higher than that of precipitation to total water consumption amount, suggesting the relatively wide regulation range of soil water use efficiency. The proportions of irrigation amount, precipitation, and soil water consumption amount to total water consumption amount were 31.0%, 38.9%, and 30.1% in treatment W3 (irrigated at jointing and flowering stages, with total irrigation amount of 120 mm), and 51.7%, 32.4%, and 15.9% in treatment W5 (irrigated before winter and at jointing, flowering and grain-filling stages, with total irrigation amount of 240 mm), respectively, indicating that treatment W3 had a significantly higher proportion of soil water consumption amount to total water consumption amount than treatment W5. Though treatments W2 (irrigated before winter and at jointing stage) and W3 (irrigated at jointing and flowering stages) had the same irrigation amount (120 mm), the water consumption amount during the period from flowering to maturing was significantly higher in W3 than in W2, while the water consumption amount before jointing was significantly lower in W3 than in W2. The water consumption pattern in treatment W3 was in agreement with the water requirement pattern of wheat, which was the physiological basis of high water use efficiency.

  11. Aluminum and Alzheimer's disease: after a century of controversy, is there a plausible link?

    PubMed

    Tomljenovic, Lucija

    2011-01-01

    The brain is a highly compartmentalized organ exceptionally susceptible to accumulation of metabolic errors. Alzheimer's disease (AD) is the most prevalent neurodegenerative disease of the elderly and is characterized by regional specificity of neural aberrations associated with higher cognitive functions. Aluminum (Al) is the most abundant neurotoxic metal on earth, widely bioavailable to humans and repeatedly shown to accumulate in AD-susceptible neuronal foci. In spite of this, the role of Al in AD has been heavily disputed based on the following claims: 1) bioavailable Al cannot enter the brain in sufficient amounts to cause damage, 2) excess Al is efficiently excreted from the body, and 3) Al accumulation in neurons is a consequence rather than a cause of neuronal loss. Research, however, reveals that: 1) very small amounts of Al are needed to produce neurotoxicity and this criterion is satisfied through dietary Al intake, 2) Al sequesters different transport mechanisms to actively traverse brain barriers, 3) incremental acquisition of small amounts of Al over a lifetime favors its selective accumulation in brain tissues, and 4) since 1911, experimental evidence has repeatedly demonstrated that chronic Al intoxication reproduces neuropathological hallmarks of AD. Misconceptions about Al bioavailability may have misled scientists regarding the significance of Al in the pathogenesis of AD. The hypothesis that Al significantly contributes to AD is built upon very solid experimental evidence and should not be dismissed. Immediate steps should be taken to lessen human exposure to Al, which may be the single most aggravating and avoidable factor related to AD.

  12. Episodic Memory and Appetite Regulation in Humans

    PubMed Central

    Brunstrom, Jeffrey M.; Burn, Jeremy F.; Sell, Nicola R.; Collingwood, Jane M.; Rogers, Peter J.; Wilkinson, Laura L.; Hinton, Elanor C.; Maynard, Olivia M.; Ferriday, Danielle

    2012-01-01

    Psychological and neurobiological evidence implicates hippocampal-dependent memory processes in the control of hunger and food intake. In humans, these have been revealed in the hyperphagia that is associated with amnesia. However, it remains unclear whether ‘memory for recent eating’ plays a significant role in neurologically intact humans. In this study we isolated the extent to which memory for a recently consumed meal influences hunger and fullness over a three-hour period. Before lunch, half of our volunteers were shown 300 ml of soup and half were shown 500 ml. Orthogonal to this, half consumed 300 ml and half consumed 500 ml. This process yielded four separate groups (25 volunteers in each). Independent manipulation of the ‘actual’ and ‘perceived’ soup portion was achieved using a computer-controlled peristaltic pump. This was designed to either refill or draw soup from a soup bowl in a covert manner. Immediately after lunch, self-reported hunger was influenced by the actual and not the perceived amount of soup consumed. However, two and three hours after meal termination this pattern was reversed - hunger was predicted by the perceived amount and not the actual amount. Participants who thought they had consumed the larger 500-ml portion reported significantly less hunger. This was also associated with an increase in the ‘expected satiation’ of the soup 24-hours later. For the first time, this manipulation exposes the independent and important contribution of memory processes to satiety. Opportunities exist to capitalise on this finding to reduce energy intake in humans. PMID:23227200

  13. Species variation in home garden agroforestry system in South Sulawesi, Indonesia and its contribution to farmers’ income

    NASA Astrophysics Data System (ADS)

    Paembonan, S. A.; Millang, S.; Dassir, M.; Ridwan, M.

    2018-05-01

    Home-garden is one of the types of agroforestry which is commonly practiced by rural communities in South Sulawesi, Indonesia. The study aimed to determine the diversity levels of the species constituting the home-gardens and their contribution to the farmers’ incomes. The variables used in the study were the widths variation of the land owned as the home-gardens and the socioeconomic backgrounds of the community. The study results indicated that in small land, the community cultivated annual crop plants interspersed with agricultural commodities, and the trees as the boundary, while in the wider land they integrated various species plants within the area. The diversity index of the home-gardens was categorized as moderate with a value of 1.25 to 2.18, while species uniformity index was ranging from moderate to high with values of 0.49 to 0.77. The total incomes from home gardens varied greatly from one community to another, and it was largely determined by the composition and density of the constituent species. The contribution of the home-gardens to the income of the farmers amounted to 43.27%–49.06%. The sustainable management of the home-garden agroforestry can give a significant contribution to the farmers’ incomes and the preservation of biodiversity and environment.

  14. Volatile Organic Compounds: Characteristics, distribution and sources in urban schools

    NASA Astrophysics Data System (ADS)

    Mishra, Nitika; Bartsch, Jennifer; Ayoko, Godwin A.; Salthammer, Tunga; Morawska, Lidia

    2015-04-01

    Long term exposure to organic pollutants, both inside and outside school buildings may affect children's health and influence their learning performance. Since children spend significant amount of time in school, air quality, especially in classrooms plays a key role in determining the health risks associated with exposure at schools. Within this context, the present study investigated the ambient concentrations of Volatile Organic Compounds (VOCs) in 25 primary schools in Brisbane with the aim to quantify the indoor and outdoor VOCs concentrations, identify VOCs sources and their contribution, and based on these; propose mitigation measures to reduce VOCs exposure in schools. One of the most important findings is the occurrence of indoor sources, indicated by the I/O ratio >1 in 19 schools. Principal Component Analysis with Varimax rotation was used to identify common sources of VOCs and source contribution was calculated using an Absolute Principal Component Scores technique. The result showed that outdoor 47% of VOCs were contributed by petrol vehicle exhaust but the overall cleaning products had the highest contribution of 41% indoors followed by air fresheners and art and craft activities. These findings point to the need for a range of basic precautions during the selection, use and storage of cleaning products and materials to reduce the risk from these sources.

  15. 75 FR 2068 - Definition of “Plan Assets”-Participant Contributions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-14

    ... 7 business days. Thus, the two-day longer reasonable period also has the advantage of being... to the 15th business day of the month following the month in which participant contributions are... the 15th business day of the month following the month in which such amounts would otherwise have been...

  16. 23 CFR 710.507 - State and local contributions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false State and local contributions. 710.507 Section 710.507... certification that the acquisition satisfied the conditions in 23 CFR 710.501(b); and (2) Justification of the... conditions in 23 CFR 710.501(b), and that documentation justifies the amount of the credit. ...

  17. 26 CFR 1.105-1 - Amounts attributable to employer contributions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... benefits as well as other benefits for the employees, and if the respective contributions made by the... received by an employee through accident or health insurance for personal injuries or sickness must be... employer which were not includible in the gross income of the employee, or (2) are paid by the employer...

  18. The Prediction of Achievement and Time Spent in Instruction in a Self-Paced Individualized Course.

    ERIC Educational Resources Information Center

    Franklin, Thomas E.

    Multiple linear regressions were employed to determine the relative contributions of cognitive and affective variables accounting for variance in college students' achievement and amount of time taken to complete a self-paced, individualized course. Study habits and attitudes (SSHA) made greater relative contributions to explaining total course…

  19. 29 CFR 4204.13 - Net income and net tangible assets tests.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... LIABILITY FOR MULTIEMPLOYER PLANS VARIANCES FOR SALE OF ASSETS Variance of the Statutory Requirements § 4204... purchaser was not obligated to contribute to the plan before the sale, the amount of unfunded vested... date of determination, or (ii) If the purchaser was obligated to contribute to the plan before the sale...

  20. Effect of Dietary Oxalate on the Gut Microbiota of the Mammalian Herbivore Neotoma albigula

    PubMed Central

    Oakeson, Kelly F.; Dale, Colin; Dearing, M. Denise

    2016-01-01

    Diet is one of the primary drivers that sculpts the form and function of the mammalian gut microbiota. However, the enormous taxonomic and metabolic diversity held within the gut microbiota makes it difficult to isolate specific diet-microbe interactions. The objective of the current study was to elucidate interactions between the gut microbiota of the mammalian herbivore Neotoma albigula and dietary oxalate, a plant secondary compound (PSC) degraded exclusively by the gut microbiota. We quantified oxalate degradation in N. albigula fed increasing amounts of oxalate over time and tracked the response of the fecal microbiota using high-throughput sequencing. The amount of oxalate degraded in vivo was linearly correlated with the amount of oxalate consumed. The addition of dietary oxalate was found to impact microbial species diversity by increasing the representation of certain taxa, some of which are known to be capable of degrading oxalate (e.g., Oxalobacter spp.). Furthermore, the relative abundances of 117 operational taxonomic units (OTU) exhibited a significant correlation with oxalate consumption. The results of this study indicate that dietary oxalate induces complex interactions within the gut microbiota that include an increase in the relative abundance of a community of bacteria that may contribute either directly or indirectly to oxalate degradation in mammalian herbivores. PMID:26896138

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Konapala, Goutam; Mishra, Ashok; Leung, L. Ruby

    This study investigated the anthropogenic influence on the temporal variability of annual precipitation for the period 1950-2005 as simulated by the CMIP5 models. The temporal variability of both annual precipitation amount (PRCPTOT) and intensity (SDII) was first measured using a metric of statistical dispersion called the Gini coefficient. Comparing simulations driven by both anthropogenic and natural forcings (ALL) with simulations of natural forcings only (NAT), we quantified the anthropogenic contributions to the changes in temporal variability at global, continental and sub-continental scales as a relative difference of the respective Gini coefficients of ALL and NAT. Over the period of 1950-2005,more » our results indicate that anthropogenic forcings have resulted in decreased uniformity (i.e., increase in unevenness or disparity) in annual precipitation amount and intensity at global as well as continental scales. In addition, out of the 21 sub-continental regions considered, 14 (PRCPTOT) and 17 (SDII) regions showed significant anthropogenic influences. The human impacts are generally larger for SDII compared to PRCTOT, indicating that the temporal variability of precipitation intensity is generally more susceptible to anthropogenic influence than precipitation amount. Lastly, the results highlight that anthropogenic activities have changed not only the trends but also the temporal variability of annual precipitation, which underscores the need to develop effective adaptation management practices to address the increased disparity.« less

  2. Molecular and Immunological Characterization of Ragweed (Ambrosia artemisiifolia L.) Pollen after Exposure of the Plants to Elevated Ozone over a Whole Growing Season

    PubMed Central

    Kanter, Ulrike; Heller, Werner; Durner, Jörg; Winkler, J. Barbro; Engel, Marion; Behrendt, Heidrun; Holzinger, Andreas; Braun, Paula; Hauser, Michael; Ferreira, Fatima; Mayer, Klaus; Pfeifer, Matthias; Ernst, Dieter

    2013-01-01

    Climate change and air pollution, including ozone is known to affect plants and might also influence the ragweed pollen, known to carry strong allergens. We compared the transcriptome of ragweed pollen produced under ambient and elevated ozone by 454-sequencing. An enzyme-linked immunosorbent assay (ELISA) was carried out for the major ragweed allergen Amb a 1. Pollen surface was examined by scanning electron microscopy and attenuated total reflectance–Fourier transform infrared spectroscopy (ATR-FTIR), and phenolics were analysed by high-performance liquid chromatography. Elevated ozone had no influence on the pollen size, shape, surface structure or amount of phenolics. ATR-FTIR indicated increased pectin-like material in the exine. Transcriptomic analyses showed changes in expressed-sequence tags (ESTs), including allergens. However, ELISA indicated no significantly increased amounts of Amb a 1 under elevated ozone concentrations. The data highlight a direct influence of ozone on the exine components and transcript level of allergens. As the total protein amount of Amb a 1 was not altered, a direct correlation to an increased risk to human health could not be derived. Additional, the 454-sequencing contributes to the identification of stress-related transcripts in mature pollen that could be grouped into distinct gene ontology terms. PMID:23637846

  3. Hyperforin in St. John's wort drug interactions.

    PubMed

    Madabushi, Rajanikanth; Frank, Bruno; Drewelow, Bernd; Derendorf, Hartmut; Butterweck, Veronika

    2006-03-01

    Recently, interactions of herbal medicines with synthetic drugs came into focus of particular interest. In the past 3 years, more than 50 papers were published regarding interactions between St. John's wort (Hypericum perforatum L.; SJW) and prescription drugs. Co-medication with SJW resulted in decreased plasma concentrations of a number of drugs including amitriptyline, cyclosporine, digoxin, indinavir, irinotecan, warfarin, phenprocoumon, alprazolam, dextrometorphane, simvastatin, and oral contraceptives. Sufficient evidence from interaction studies and case reports indicate that SJW is a potent inducer of cytochrome P450 enzymes (particularly CYP3A4) and/or P-glycoprotein. Recent studies could show that the degree of enzyme induction by SJW correlates strongly with the amount of hyperforin found in the product. Products that do not contain substantial amounts of hyperforin (<1%) have not been shown to produce clinically relevant enzyme induction. On the other hand, some evidence suggests that hyperforin may also contribute to the antidepressant activity of SJW. However, clinical studies using SJW preparations with a low hyperforin amount (<1%) clearly demonstrated the superiority of this plant extract over placebo and its equivalence to imipramine and fluoxetine in the treatment of mild to moderate forms of depression. In the present paper clinical significant SJW interactions are critically evaluated against the background of hyperforin.

  4. The heating of dust in starburst galaxies: The contribution of the nonionizing radiation

    NASA Technical Reports Server (NTRS)

    Calzetti, D.; Bohlin, R. C.; Kinney, Anne L.; Storchi-Bergmann, T.; Heckman, Timothy M.

    1995-01-01

    The IUE UV and optical spectra and the far-infrared (FIR) IRAS flux densities of a sample of starburst and blue compact galaxies are used to investigate the relationship between dust obscuration and dust emission. The amount of dust obscuration at UV wavelengths correlates with the FIR-to-blue ratio; and an analysis of the correlation indicates that not only the ionizing but also the nonionizing radiation contribute to the FIR emission. The amount of UV and optical energy lost to dust obscuration accounts for most of the cool dust FIUR emission and for about 70% of the warm dust FIR emission. The remaining 30% of the warm dust FIR flux is probably due to dust emission from regions of star formation which are embedded in opaque giant molecular clouds and do not contribute to the integrated UV and optical spectrum. The use of the FIR emission as an indicator of high-mass star formation rate in star-forming galaxies can be problematic, since the contribution to the FIR flux from cool dust emission heated by relatively old stars is nonnegligible.

  5. The importance of having a partner: male help releases females from time limitation during incubation in birds.

    PubMed

    Matysioková, Beata; Remeš, Vladimír

    2014-03-07

    Male contribution to parental care varies widely among avian species. Yet the reasons for this variation, as well as its consequences, are still unclear. Because the amount of care provided by one sex is ultimately constrained by the time available for energy acquisition, contribution by the other sex should increase when overall parental workload is high. We tested this prediction by analyzing male contribution to incubation in 528 populations of 320 species of passerines, where females usually devote more time to incubation than males. Our worldwide sample included species with female-only parental care (the male is not present), incubation feeding (the male feeds the incubating female), and shared incubation (both sexes incubate the eggs). Overall nest attentiveness was greatest in species with shared incubation followed by species with incubation feeding and lowest in species with female-only care. Nest attentiveness and the degree of male contribution to incubation in species with shared incubation were very strongly correlated, whereas this correlation was absent in females. Interestingly, female contribution decreased towards the equator while male contribution did not change significantly with latitude. Hence, relative male incubation effort increased towards the equator, whereas that of female decreased. In species with incubation feeding, female nest attentiveness increased with the frequency of male feeding. These findings support the hypothesis that male help is indispensable for increasing nest attentiveness in birds, either in the form of incubation feeding (supply of energy) or direct incubation of eggs. We conclude that energy acquisition constraints might be a potent force driving sex-specific contribution to parental care.

  6. Biodegradability of algal-derived organic matter in a large artificial lake by using stable isotope tracers.

    PubMed

    Lee, Yeonjung; Lee, Bomi; Hur, Jin; Min, Jun-Oh; Ha, Sun-Yong; Ra, Kongtae; Kim, Kyung-Tae; Shin, Kyung-Hoon

    2016-05-01

    In order to understand the biodegradability of algal-derived organic matter, biodegradation experiments were conducted with (13)C and (15)N-labeled natural phytoplankton and periphytic algal populations in experimental conditions for 60 days. Qualitative changes in the dissolved organic matter were also determined using parallel factor analysis and the stable carbon isotopic composition of the hydrophobic dissolved organic matter through the experimental period. Although algal-derived organic matter is considered to be easily biodegradable, the initial amounts of total organic carbon newly produced by phytoplankton and periphytic algae remained approximately 16 and 44 % after 60 days, respectively, and about 22 and 43 % of newly produced particulate nitrogen remained. Further, the dissolved organic carbon derived from both algal populations increased significantly after 60 days. Although the dissolved organic matter gradually became refractory, the contributions of the algal-derived organic matter to the dissolved organic matter and hydrophobic dissolved organic matter increased. Our laboratory experimental results suggest that algal-derived organic matter produced by phytoplankton and periphytic algae could contribute significantly to the non-biodegradable organic matter through microbial transformations.

  7. Role of interfacial charge in the piezoelectric properties of ferroelectric 0-3 composites

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wong, C.K.; Shin, F.G.; Department of Applied Physics, Materials Research Center and Center for Smart Materials, Hong Kong Polytechnic University, Hong Kong

    2005-02-01

    We investigated the effects of compensating charges (at the inclusion-matrix interface) on the piezoelectric properties of ferroelectric 0-3 composites. Our previously developed model [C. K. Wong, Y. M. Poon, and F. G. Shin, J. Appl. Phys. 90, 4690 (2001)] has been extended to include the additional contribution from the deformation of the inclusion particles due to the applied stress in the piezoelectric measurement. The relative significance of this contribution is mainly determined by the amount of compensating interfacial charge, which is significantly governed by the degrees of poling of the constituent materials in the composite sample. This model provides anmore » explanation to an anomaly in the piezoelectric coefficients of 0-3 composite samples with the matrix and inclusion phases polarized in opposite directions. Explicit expressions in closed form have been derived for the effective d{sub 33}, d{sub 31}, and d{sub h} coefficients. After taking into consideration the degree of poling of the constituents and the effects of the compensating interfacial charges, theoretical predictions show good agreement with published experimental data. Goodness of fit is not limited to low volume concentration of inclusions.« less

  8. Metabolic profiling of sourdough fermented wheat and rye bread.

    PubMed

    Koistinen, Ville M; Mattila, Outi; Katina, Kati; Poutanen, Kaisa; Aura, Anna-Marja; Hanhineva, Kati

    2018-04-09

    Sourdough fermentation by lactic acid bacteria is commonly used in bread baking, affecting several attributes of the final product. We analyzed whole-grain wheat and rye breads and doughs prepared with baker's yeast or a sourdough starter including Candida milleri, Lactobacillus brevis and Lactobacillus plantarum using non-targeted metabolic profiling utilizing LC-QTOF-MS. The aim was to determine the fermentation-induced changes in metabolites potentially contributing to the health-promoting properties of whole-grain wheat and rye. Overall, we identified 118 compounds with significantly increased levels in sourdough, including branched-chain amino acids (BCAAs) and their metabolites, small peptides with high proportion of BCAAs, microbial metabolites of phenolic acids and several other potentially bioactive compounds. We also identified 69 compounds with significantly decreased levels, including phenolic acid precursors, nucleosides, and nucleobases. Intensive sourdough fermentation had a higher impact on the metabolite profile of whole-grain rye compared to milder whole-grain wheat sourdough fermentation. We hypothesize that the increased amount of BCAAs and potentially bioactive small peptides may contribute to the insulin response of rye bread, and in more general, the overall protective effect against T2DM and CVD.

  9. Methane hydrate-bearing seeps as a source of aged dissolved organic carbon to the oceans

    USGS Publications Warehouse

    Pohlman, J.W.; Bauer, J.E.; Waite, W.F.; Osburn, C.L.; Chapman, N.R.

    2011-01-01

    Marine sediments contain about 500-10,000 Gt of methane carbon, primarily in gas hydrate. This reservoir is comparable in size to the amount of organic carbon in land biota, terrestrial soils, the atmosphere and sea water combined, but it releases relatively little methane to the ocean and atmosphere. Sedimentary microbes convert most of the dissolved methane to carbon dioxide. Here we show that a significant additional product associated with microbial methane consumption is methane-derived dissolved organic carbon. We use ??14 C and ??13 C measurements and isotopic mass-balance calculations to evaluate the contribution of methane-derived carbon to seawater dissolved organic carbon overlying gas hydrate-bearing seeps in the northeastern Pacific Ocean. We show that carbon derived from fossil methane accounts for up to 28% of the dissolved organic carbon. This methane-derived material is much older, and more depleted in 13 C, than background dissolved organic carbon. We suggest that fossil methane-derived carbon may contribute significantly to the estimated 4,000-6,000 year age of dissolved organic carbon in the deep ocean, and provide reduced organic matter and energy to deep-ocean microbial communities. ?? 2011 Macmillan Publishers Limited. All rights reserved.

  10. Descending pathways to the spinal cord, IV: Some factors related to the amount of cortex devoted to the corticospinal tract.

    PubMed

    Nudo, R J; Masterton, R B

    1990-06-22

    In the companion paper to this one (Nudo and Masterton: J. Comp. Neurol. 296:559-583, '90), we have presented data indicating that in each of 22 mammals, there are either 2 or 3 separate regions of neocortex contributing corticospinal fibers. In this paper, we describe the variation in the absolute size of these cortical regions, the total amount of neocortex contributing corticospinal fibers (CST cortex), and the total amount of neocortex (total cortex) in each of the animals. We then use strict statistical tests to examine the relationships between these measures and several other quantitative measures or descriptions of the animals' size, ancestral heritage, motor prowess, and ecological adaptation. The results show that the absolute amount of CST cortex is more closely related to the total amount of neocortex than to any other quantitative measure available. The further variation--that is, the variation in the amount of CST cortex relative to total neocortex--appears to have been random over the inferred ancestral lineages of most animals in the sample, but seems to have been almost absent along the anthropoid lineage. Because this constancy in the relative amount of CST cortex over a very long period of anthropoid ancestry is apparently unusual if not unique among mammals, it may contain a clue to the special role of the corticospinal tract among primates. Finally, the distribution of the CST among the 3 cortical regions in primates was found to be more closely related to their particular mode of ecological adaptation than to their particular combination of digital dexterity and hand-eye coordination.

  11. Presence and leaching of bisphenol a (BPA) from dental materials

    PubMed Central

    Becher, Rune; Wellendorf, Hanne; Sakhi, Amrit Kaur; Samuelsen, Jan Tore; Thomsen, Cathrine; Bølling, Anette Kocbach; Kopperud, Hilde Molvig

    2018-01-01

    Abstract BPA has been reported to leach from some resin based dental restorative materials and materials used for orthodontic treatment. To confirm and update previous findings, especially in light of the new temporary lower threshold value for tolerable daily BPA intake, we have investigated the leaching of BPA from 4 composite filling materials, 3 sealants and 2 orthodontic bonding materials. The materials were either uncured and dissolved in methanol or cured. The cured materials were kept in deionized water for 24 hours or 2 weeks. Samples were subsequently analyzed by ultra-performance liquid chromatography coupled to mass spectrometry (UPLC-MS-MS). The composite filling material Tetric EvoFlow® and the fissure sealant DELTON® showed significantly higher levels of BPA leaching compared to control samples for all test conditions (uncured, 24 h leaching and 2 weeks leaching). There were no significant differences in amount of leached BPA for any of the tested materials after 24 hours compared to 2 weeks. These results show that BPA is still released from some dental materials despite the general concern about potential adverse effects of BPA. However, the amounts of BPA were relatively low and most likely represent a very small contribution to the total BPA exposure. PMID:29868625

  12. Batch sorption results for neptunium transport through Yucca Mountain tuffs. Yucca Mountain Site Characterization Program milestone 3349

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Triay, I.R.; Cotter, C.R.; Huddleston, M.H.

    1996-09-01

    We studied the sorption of neptunium onto tuffs characteristic of the proposed nuclear waste repository at Yucca Mountain, Nevada. The neptunium was in the Np(V) oxidation state under oxidizing conditions in groundwaters from two wells located close to the repository site (J-13 and UE-25 p No.1). We used devitrified, vitric, zeolitic (with emphasis on clinoptilolite-rich samples), and calcite-rich tuffs characteristic of the geology of the site. Neptunium sorbed well onto calcite and calcite-rich tuffs, indicating that a significant amount of neptunium retardation can be expected under fractured-flow scenarios because of calcite coating of the fractures. Neptunium sorption onto clinoptilolite-rich zeoliticmore » tuffs in J-13 well water (pH from 7 to 8.5) was moderate, increased with decreasing pH, and correlated to surface area and amount of clinoptilolite. Neptunium sorbed poorly onto zeolitic tuffs from UE-25 p No.1 groundwater (pH from 7 to 9) and onto devitrified and vitric tuffs from J-13 and UE-25 p No.1 waters (pH from 7 to 9). Iron oxides appeared to be passivated in tuffs, not seeming to contribute to the observed neptunium sorption, even though neptunium sorption onto synthetic iron oxide is significant.« less

  13. Pears and renal stones: possible weapon for prevention? A comprehensive narrative review.

    PubMed

    Manfredini, R; De Giorgi, A; Storari, A; Fabbian, F

    2016-01-01

    Urinary stones have been recognized as a human disease since dawn of history and treatment of this condition is reported by Egyptian medical writings. Also, pears have a very long history, being one of the earliest cultivated fruit trees and also known for medicinal use. Urinary tract stone formation represents a common condition and also a significant burden for health care service, due also to possible frequent relapses. Furthermore, urinary stones have been reported to have relationship with different metabolic derangements, and appropriate diet could contribute to avoid or reduce urinary stone formation. Citrate is an inhibitor of crystal growth in the urinary system, and hypocitraturia represents a main therapeutical target in stone formers. Pears contain a significant amount of malic acid, a precursor of citrate, and have antioxidant activity as well. A diet supplemented with pears, and associated with low consumption of meat and salt could impact positively cardiometabolic risk and urinary tract stone formation. However, very few studies evaluated the impact of pears utilization on health, and none on urinary tract stone formation in particular. High content in malate could warrant protection against stone formation, avoiding patients at high risk to be compelled to assume a considerable and expensive amount of pills.

  14. Effects of content and surface hydrophobic modification of BaTiO3 on the cooling properties of ASA (acrylonitrile-styrene-acrylate copolymer)

    NASA Astrophysics Data System (ADS)

    Xiang, Bo; Zhang, Jun

    2018-01-01

    For the field of cool material, barium titanate (BaTiO3, BT) is still a new member that needs to be further studied. Herein, the effects of both content and surface hydrophobic modification of BT on the cooling properties of acrylonitrile-styrene-acrylate copolymer (ASA) were detailedly investigated, aiming to fabricate composited cool material. Butyl acrylate (BA) was employed to convert the surface of BT from hydrophilic to hydrophobic. The addition of unmodified BT could significantly improve the solar reflectance of ASA, especially when the addition amount is 3 vol%, the near infrared (NIR) reflectance increased from 22.02 to 72.60%. However, serious agglomeration occurred when the addition amount increased to 5 vol% and therefore led to a relatively smaller increase in solar reflectance and an obvious decline in impact strength. After surface hydrophobic modification, the modified BT (M-BT) presented better dispersibility in ASA matrix, which contributed to the improvement of both solar reflectance and impact strength. In addition, the temperature test provided a more sufficient and intuitive way to evaluate the cooling effect of the composited cool materials, and a significant decrease (over 10 °C) could be achieved in the temperature test when M-BT particles were introduced.

  15. Municipal solid waste management in Tehran: Changes during the last 5 years.

    PubMed

    Malmir, Tahereh; Tojo, Yasumasa

    2016-05-01

    The situation of waste management in Tehran was a typical example of it in developing countries. The amount of municipal solid waste has been increasing and the city has depended on landfill for municipal solid waste management. However, in recent years, various measures have been taken by the city, such as collecting recyclables at the source and increasing the capacity of waste-processing facilities. As a result, significant changes in the waste stream are starting to occur. This study investigated the nature of, and reasons for, the marked changes in the waste stream from 2008 to 2012 by analysing the municipal solid waste statistics published by the Tehran Waste Management Organization in 2013 and survey data on the physical composition of the municipal solid waste. The following trends were identified: Although the generation of municipal solid waste increased by 10% during the 5-year period, the amount of waste directly disposed of to landfill halved and resource recovery almost doubled. An increase in the capacity of a waste-processing facility contributed significantly to these changes. The biodegradable fraction going to landfill was estimated by using the quantity and the composition of each input to the landfill. The estimated result in 2012 decreased to 49% of its value in 2008. © The Author(s) 2016.

  16. Helping patterns and reproductive success in Aymara communities.

    PubMed

    Crognier, E; Villena, M; Vargas, E

    2002-01-01

    "Helpers at the nest," young adults remaining in their parents home to take care of younger siblings, are known in many species of birds and mammals. Similar behaviors are occasionally observed in human societies but their frequency and significance for parental reproductive success are still not fully appraised. This study was designed to document this issue in a traditional Aymara peasant society of the Bolivian Altiplano, It is based on 359 reproductive life histories of women 45 years of age or older and on a survey of children's workload in 1998 and 1999. The presence of "potential helpers" in the household is significantly associated with higher fertility and with improved survival of siblings to sexual maturity. Caretaking is not particularly assigned to older daughters. The positive relationship between the availability of offspring help and reproductive success does not demonstrate a causal role for child caretaking because, in contrast with nonhuman helpers, workloads of children range from housekeeping to agricultural tasks, instead of being focused on feeding or protecting younger siblings. Correlation and multiple regression analyses, however, suggest that the total amount of care given by the older offspring and the amount of care received by each recipient are, along with offspring contribution to household economy, among the determinants of parental reproductive success. Copyright 2002 Wiley-Liss, Inc.

  17. [Evaluation on self-pollution of marine culture in the Yellow Sea and Bohai Sea].

    PubMed

    Cui, Yi; Chen, Bijuan; Chen, Jufa

    2005-01-01

    This paper studied the respective contribution of feeding and non-feeding marine culture on seawater and red tide occurrence. The results showed that the annual output of marine had a positive correlation with the nutrients and COD in the Yellow Sea and Bohai Sea, of which, the correlation between DIN content and shrimp yield was significant. The output also had a positive correlation with the occurrence times of red tide recorded in the Yellow and Sea Bohai Sea. These results illustrated that the self-pollution of marine culture had a significant influence on the eutrophication and red tide occurred in the neighboring waters. It was estimated that the amounts of N, P and COD entered into seawater through the marine culture in the Yellow Sea and Bohai Sea accounted for 2.8%, 5.3% and 1.8% of the amounts of corresponding land-based pollutants entered to the sea, respectively. Although the discharge of the pollutants produced by marine culture was less than that produced by other human activities, some local waters, especially dense marine culture areas, would bring out some additive effects on environment. Therefore, the pollutants discharged by marine culture were very likely to be an important factor stimulating the eutrophication and red tide occurrence in coastal waters, which should be paid adequate attention.

  18. An early geodynamo driven by exsolution of mantle components from Earth’s core

    PubMed Central

    Badro, James; Siebert, Julien; Nimmo, Francis

    2016-01-01

    Terrestrial core formation occurred in the early molten Earth by gravitational segregation of immiscible metal and silicate melts, stripping iron-loving elements from the silicate mantle to the metallic core1–3, and leaving rock-loving components behind. Here we performed experiments showing that at high enough temperature, Earth’s major rock-loving component, magnesium oxide, can also dissolve in core-forming metallic melts. Our data clearly point to a dissolution reaction, and are in agreement with recent DFT calculations4. Using core formation models5, we further show that a high-temperature event during Earth’s accretion (such as the Moon-forming giant impact6) can contribute significant amounts of magnesium to the early core. As it subsequently cools, the ensuing exsolution7 of buoyant magnesium oxide generates a substantial amount of gravitational energy. This energy is comparable to if not significantly higher than that produced by inner core solidification8 — the primary driver of the Earth’s current magnetic field9–11. Since the inner core is too young12 to explain the existence of an ancient field prior to ~1 billion years, our results solve the conundrum posed by the recent paleomagnetic observation13 of an ancient field at least 3.45 Gyr old. PMID:27437583

  19. LOX Tank Helium Removal for Propellant Scavenging

    NASA Technical Reports Server (NTRS)

    Chato, David J.

    2009-01-01

    System studies have shown a significant advantage to reusing the hydrogen and oxygen left in these tanks after landing on the Moon in fuel cells to generate power and water for surface systems. However in the current lander concepts, the helium used to pressurize the oxygen tank can substantially degrade fuel cell power and water output by covering the reacting surface with inert gas. This presentation documents an experimental investigation of methods to remove the helium pressurant while minimizing the amount of the oxygen lost. This investigation demonstrated that significant quantities of Helium (greater than 90% mole fraction) remain in the tank after draining. Although a single vent cycle reduced the helium quantity, large amounts of helium remained. Cyclic venting appeared to be more effective. Three vent cycles were sufficient to reduce the helium to small (less than 0.2%) quantities. Two vent cycles may be sufficient since once the tank has been brought up to pressure after the second vent cycle the helium concentration has been reduced to the less than 0.2% level. The re-pressurization process seemed to contribute to diluting helium. This is as expected since in order to raise the pressure liquid oxygen must be evaporated. Estimated liquid oxygen loss is on the order of 82 pounds (assuming the third vent cycle is not required).

  20. Quantitative relationships between occupant satisfaction and satisfaction aspects of indoor environmental quality and building design.

    PubMed

    Frontczak, M; Schiavon, S; Goins, J; Arens, E; Zhang, H; Wargocki, P

    2012-04-01

    The article examines which subjectively evaluated indoor environmental parameters and building features mostly affect occupants' satisfaction in mainly US office buildings. The study analyzed data from a web-based survey administered to 52,980 occupants in 351 office buildings over 10 years by the Center for the Built Environment. The survey uses 7-point ordered scale questions pertaining to satisfaction with indoor environmental parameters, workspace, and building features. The average building occupant was satisfied with his/her workspace and building. Proportional odds ordinal logistic regression shows that satisfaction with all 15 parameters listed in the survey contributed significantly to overall workspace satisfaction. The most important parameters were satisfaction with amount of space (odds ratio OR 1.57, 95% CI: 1.55-1.59), noise level (OR 1.27, 95% CI: 1.25-1.29), and visual privacy (OR 1.26, 95% CI: 1.24-1.28). Satisfaction with amount of space was ranked to be most important for workspace satisfaction, regardless of age group (below 30, 31-50 or over 50 years old), gender, type of office (single or shared offices, or cubicles), distance of workspace from a window (within 4.6 m or further), or satisfaction level with workspace (satisfied or dissatisfied). Satisfaction with amount of space was not related to the gross amount of space available per person. To maximize workspace satisfaction, designer should invest in aspects that increase satisfaction with amount of space and storage, noise level, and visual privacy. Office workers will be most satisfied with their workspace and building when located close to a window in a private office. This may affect job satisfaction, work performance, and personal and company productivity. © 2011 John Wiley & Sons A/S.

  1. Integrated Platform for Expedited Synthesis–Purification–Testing of Small Molecule Libraries

    PubMed Central

    2017-01-01

    The productivity of medicinal chemistry programs can be significantly increased through the introduction of automation, leading to shortened discovery cycle times. Herein, we describe a platform that consolidates synthesis, purification, quantitation, dissolution, and testing of small molecule libraries. The system was validated through the synthesis and testing of two libraries of binders of polycomb protein EED, and excellent correlation of obtained data with results generated through conventional approaches was observed. The fully automated and integrated platform enables batch-supported compound synthesis based on a broad array of chemical transformations with testing in a variety of biochemical assay formats. A library turnaround time of between 24 and 36 h was achieved, and notably, each library synthesis produces sufficient amounts of compounds for further evaluation in secondary assays thereby contributing significantly to the shortening of medicinal chemistry discovery cycles. PMID:28435537

  2. Spherical indentation of a freestanding circular membrane revisited: Analytical solutions and experiments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jin, Congrui; Davoodabadi, Ali; Li, Jianlin

    Because of the development of novel micro-fabrication techniques to produce ultra-thin materials and increasing interest in thin biological membranes, in recent years, the mechanical characterization of thin films has received a significant amount of attention. To provide a more accurate solution for the relationship among contact radius, load and deflection, the fundamental and widely applicable problem of spherical indentation of a freestanding circular membrane have been revisited. The work presented here significantly extends the previous contributions by providing an exact analytical solution to the governing equations of Föppl–Hecky membrane indented by a frictionless spherical indenter. In this study, experiments ofmore » spherical indentation has been performed, and the exact analytical solution presented in this article is compared against experimental data from existing literature as well as our own experimental results.« less

  3. High concentration of H2 and O2 nanobubbles in water electrolytes and their collective optical effect

    NASA Astrophysics Data System (ADS)

    Postnikov, A. V.; Uvarov, I. V.; Lokhanin, M. V.; Svetovoy, V. B.

    2017-09-01

    Water electrolysis with a fast change of the polarity pumps in the liquid a huge amount of hydrogen and oxygen gases. In contrast with the DC electrolysis the gases do not form visible bubbles but change significantly the refractive index of the liquid nearby the electrodes from n = 1.35 to the values smaller than 1.19. The decrease of n is registered as distortion of the images of the electrodes. We argue that all the gas is collected in H2 and O2 nanobubbles with a size smaller than 200 nm. The concentration of nanobubbles with a size of 100 nm is estimated as 1021 m-3. Due to a significant contribution from the Laplace pressure the effective supersaturation reaches 500 for hydrogen and 150 for oxygen.

  4. Role of Bioreactors in Microbial Biomass and Energy Conversion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Liang; Zhang, Biao; Zhu, Xun

    Bioenergy is the world’s largest contributor to the renewable and sustainable energy sector, and it plays a significant role in various energy industries. A large amount of research has contributed to the rapidly evolving field of bioenergy and one of the most important topics is the use of the bioreactor. Bioreactors play a critical role in the successful development of technologies for microbial biomass cultivation and energy conversion. In this chapter, after a brief introduction to bioreactors (basic concepts, configurations, functions, and influencing factors), the applications of the bioreactor in microbial biomass, microbial biofuel conversion, and microbial electrochemical systems aremore » described. Importantly, the role and significance of the bioreactor in the bioenergy process are discussed to provide a better understanding of the use of bioreactors in managing microbial biomass and energy conversion.« less

  5. Spherical indentation of a freestanding circular membrane revisited: Analytical solutions and experiments

    DOE PAGES

    Jin, Congrui; Davoodabadi, Ali; Li, Jianlin; ...

    2017-01-11

    Because of the development of novel micro-fabrication techniques to produce ultra-thin materials and increasing interest in thin biological membranes, in recent years, the mechanical characterization of thin films has received a significant amount of attention. To provide a more accurate solution for the relationship among contact radius, load and deflection, the fundamental and widely applicable problem of spherical indentation of a freestanding circular membrane have been revisited. The work presented here significantly extends the previous contributions by providing an exact analytical solution to the governing equations of Föppl–Hecky membrane indented by a frictionless spherical indenter. In this study, experiments ofmore » spherical indentation has been performed, and the exact analytical solution presented in this article is compared against experimental data from existing literature as well as our own experimental results.« less

  6. Individualism/collectivism and organizational citizenship behavior.

    PubMed

    Dávila de León, María Celeste; Finkelstein, Marcia A

    2011-08-01

    Organizational citizenship behaviors (OCB) are workplace activities that exceed an employee's formal job requirements and contribute to the effective functioning of the organization. We explored the roles of the dispositional traits of individualism and collectivism in the prediction of OCB. The relationship was examined in the context of other constructs known to influence OCB, specifically, motives and identity as an organizational citizen. A total of 367 employees in 24 organizations completed surveys measuring individualism/collectivism, OCB motives, strength of organizational citizen role identity, and amount of OCB. The results showed collectivism to be a significant predictor of Organizational Concern and Prosocial Values motives, role identity, and OCB. Individualism predicted Impression Management motives and was a significant negative predictor of a role identity as one who helps others. The findings are discussed with regard to previous research in OCB.

  7. Physical activity levels at work and outside of work among Commercial Construction Workers

    PubMed Central

    Arias, Oscar E.; Caban-Martinez, Alberto J.; Umukoro, Peter E.; Okechukwu, Cassandra A.; Dennerlein, Jack T.

    2015-01-01

    Objective Characterize the number of minutes of moderate and vigorous physical activity at work and outside of work during seven consecutive days, in a sample of 55 commercial construction workers. Methods Workers wore accelerometers during work and outside work hours for seven consecutive days, and completed brief survey at the seventh day of data collection. Results From the directly measured physical activity, the average number per participant of moderate minutes of occupational physical activity and physical activity outside of work obtained in short bouts were 243 minutes (65%) and 130 minutes (35%), respectively. Directly measured minutes of vigorous occupational physical activity were significant and positively correlated with self-reported fatigue. Conclusions Among commercial construction workers, physical activity from work contributes significantly, approximately 2/3, towards a workers total amount of weekly minutes of moderate physical activity. PMID:25563543

  8. Fate of Water Pumped from Underground and Contributions to Sea Level Rise

    NASA Technical Reports Server (NTRS)

    Wada, Yoshihide; Lo, Min-Hui; Yeh, Pat J.-F.; Reager, John T.; Famiglietti, James S.; Wu, Ren-Jie; Tseng, Yu-Heng

    2016-01-01

    The contributions from terrestrial water sources to sea-level rise, other than ice caps and glaciers, are highly uncertain and heavily debated1-5. Recent assessments indicate that groundwater depletion (GWD) may become the most important positive terrestrial contribution6-10 over the next 50 years, probably equal in magnitude to the current contributions from glaciers and ice caps6. However, the existing estimates assume that nearly 100% of groundwater extracted eventually ends up in the oceans. Owing to limited knowledge of the pathways and mechanisms governing the ultimate fate of pumped groundwater, the relative fraction of global GWD that contributes to sea-level rise remains unknown. Here, using a coupled climate-hydrological model11,12 simulation, we show that only 80% of GWDends up in the ocean. An increase in runo to the ocean accounts for roughly two-thirds, whereas the remainder results from the enhanced net flux of precipitation minus evaporation over the ocean, due to increased atmospheric vapour transport from the land to the ocean. The contribution of GWD to global sea-level rise amounted to 0.02 (+/- 0.004)mm yr(sup-1) in 1900 and increased to 0.27 (+/- 0.04)mm yr(sup-1) in 2000. This indicates that existing studies have substantially overestimated the contribution of GWD to global sea-level rise by a cumulative amount of at least 10 mm during the twentieth century and early twenty-first century. With other terrestrial water contributions included, we estimate the net terrestrial water contribution during the period 1993-2010 to be +0.12 +/-0.04)mm yr(sup-1), suggesting that the net terrestrialwater contribution reported in the IPCC Fifth Assessment Report report is probably overestimated by a factor of three.

  9. Fate of water pumped from underground and contributions to sea-level rise

    NASA Astrophysics Data System (ADS)

    Wada, Yoshihide; Lo, Min-Hui; Yeh, Pat J.-F.; Reager, John T.; Famiglietti, James S.; Wu, Ren-Jie; Tseng, Yu-Heng

    2016-08-01

    The contributions from terrestrial water sources to sea-level rise, other than ice caps and glaciers, are highly uncertain and heavily debated. Recent assessments indicate that groundwater depletion (GWD) may become the most important positive terrestrial contribution over the next 50 years, probably equal in magnitude to the current contributions from glaciers and ice caps. However, the existing estimates assume that nearly 100% of groundwater extracted eventually ends up in the oceans. Owing to limited knowledge of the pathways and mechanisms governing the ultimate fate of pumped groundwater, the relative fraction of global GWD that contributes to sea-level rise remains unknown. Here, using a coupled climate-hydrological model simulation, we show that only 80% of GWD ends up in the ocean. An increase in runoff to the ocean accounts for roughly two-thirds, whereas the remainder results from the enhanced net flux of precipitation minus evaporation over the ocean, due to increased atmospheric vapour transport from the land to the ocean. The contribution of GWD to global sea-level rise amounted to 0.02 (+/-0.004) mm yr-1 in 1900 and increased to 0.27 (+/-0.04) mm yr-1 in 2000. This indicates that existing studies have substantially overestimated the contribution of GWD to global sea-level rise by a cumulative amount of at least 10 mm during the twentieth century and early twenty-first century. With other terrestrial water contributions included, we estimate the net terrestrial water contribution during the period 1993-2010 to be +0.12 (+/-0.04) mm yr-1, suggesting that the net terrestrial water contribution reported in the IPCC Fifth Assessment Report report is probably overestimated by a factor of three.

  10. Interspecies and Intraspecies Analysis of Trehalose Contents and the Biosynthesis Pathway Gene Family Reveals Crucial Roles of Trehalose in Osmotic-Stress Tolerance in Cassava

    PubMed Central

    Han, Bingying; Fu, Lili; Zhang, Dan; He, Xiuquan; Chen, Qiang; Peng, Ming; Zhang, Jiaming

    2016-01-01

    Trehalose is a nonreducing α,α-1,1-disaccharide in a wide range of organisms, and has diverse biological functions that range from serving as an energy source to acting as a protective/signal sugar. However, significant amounts of trehalose have rarely been detected in higher plants, and the function of trehalose in the drought-tolerant crop cassava (Manihot esculenta Crantz) is unclear. We measured soluble sugar concentrations of nine plant species with differing levels of drought tolerance and 41 cassava varieties using high-performance liquid chromatography with evaporative light-scattering detector (HPLC-ELSD). Significantly high amounts of trehalose were identified in drought-tolerant crops cassava, Jatropha curcas, and castor bean (Ricinus communis). All cassava varieties tested contained high amounts of trehalose, although their concentrations varied from 0.23 to 1.29 mg·g−1 fresh weight (FW), and the trehalose level was highly correlated with dehydration stress tolerance of detached leaves of the varieties. Moreover, the trehalose concentrations in cassava leaves increased 2.3–5.5 folds in response to osmotic stress simulated by 20% PEG 6000. Through database mining, 24 trehalose pathway genes, including 12 trehalose-6-phosphate synthases (TPS), 10 trehalose-6-phosphate phosphatases (TPP), and two trehalases were identified in cassava. Phylogenetic analysis indicated that there were four cassava TPS genes (MeTPS1–4) that were orthologous to the solely active TPS gene (AtTPS1 and OsTPS1) in Arabidopsis and rice, and a new TPP subfamily was identified in cassava, suggesting that the trehalose biosynthesis activities in cassava had potentially been enhanced in evolutionary history. RNA-seq analysis indicated that MeTPS1 was expressed at constitutionally high level before and after osmotic stress, while other trehalose pathway genes were either up-regulated or down-regulated, which may explain why cassava accumulated high level of trehalose under normal conditions. MeTPS1 was then transformed into tobacco (Nicotiana benthamiana). Results indicated that transgenic tobacco lines accumulated significant level of trehalose and possessed improved drought stress tolerance. In conclusion, cassava accumulated significantly high amount of trehalose under normal conditions due to multiplied trehalose biosynthesis gene families and constant expression of the active MeTPS1 gene. High levels of trehalose subsequently contributed to high drought stress tolerance. PMID:27420056

  11. 26 CFR 1.170A-4 - Reduction in amount of charitable contributions of certain appreciated property.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., as defined in paragraph (b)(1) of this section, by the amount of gain (hereinafter in this section referred to as ordinary income) which would have been recognized as gain which is not long-term capital gain if the property had been sold by the donor at its fair market value at the time of its...

  12. 26 CFR 1.170A-4 - Reduction in amount of charitable contributions of certain appreciated property.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., as defined in paragraph (b)(1) of this section, by the amount of gain (hereinafter in this section referred to as ordinary income) which would have been recognized as gain which is not long-term capital gain if the property had been sold by the donor at its fair market value at the time of its...

  13. 26 CFR 1.170A-4 - Reduction in amount of charitable contributions of certain appreciated property.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., as defined in paragraph (b)(1) of this section, by the amount of gain (hereinafter in this section referred to as ordinary income) which would have been recognized as gain which is not long-term capital gain if the property had been sold by the donor at its fair market value at the time of its...

  14. 26 CFR 1.170A-4 - Reduction in amount of charitable contributions of certain appreciated property.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., as defined in paragraph (b)(1) of this section, by the amount of gain (hereinafter in this section referred to as ordinary income) which would have been recognized as gain which is not long-term capital gain if the property had been sold by the donor at its fair market value at the time of its...

  15. Atmospheric deposition of mercury in central Poland: Sources and seasonal trends

    NASA Astrophysics Data System (ADS)

    Siudek, Patrycja; Kurzyca, Iwona; Siepak, Jerzy

    2016-03-01

    Atmospheric deposition of total mercury was studied at two sites in central Poland, between April 2013 and October 2014. Hg in rainwater (bulk deposition) was analyzed in relation to meteorological parameters and major ions (H+, NO3-, Cl-, SO42 -) in order to investigate seasonal variation, identify sources and determine factors affecting atmospheric Hg chemistry and deposition. Total mercury concentrations varied between 1.24 and 22.1 ng L- 1 at the urban sampling site (Poznań) and between 0.57 and 18.3 ng L- 1 in the woodland protected area (Jeziory), with quite similar mean values of 6.96 and 6.37 ng L- 1, respectively. Mercury in precipitation exhibited lower spatial variability within the study domain (urban/forest transect) than the concentrations determined during other similar observations, reflecting the predominant influence of the same local sources. In our study, a significant seasonal pattern of Hg deposition was observed at both sampling sites, with higher and more variable concentrations of Hg reported for the urban area. In particular, deposition values of Hg were higher in the samples attributed to relatively large precipitation amounts in the summer and in those collected during the winter season (the result of higher contributions from combustion sources, i.e. intensive combustion of fossil fuels in residential and commercial boilers, individual power/heat-generating plants). In addition, a significant relationship between Hg concentration and precipitation amount was found while considering different types of wintertime samples (i.e. rain, snow and mixed precipitation). The analysis of backward trajectories showed that air masses arriving from polluted regions of western Europe and southern Poland largely affected the amount of Hg in rainwater. A seasonal variation in Hg deposition fluxes was also observed, with the maximum value of Hg in spring and minimum in winter. Our results indicated that rainwater Hg and, consequently, the wet deposition flux of Hg are related to seasonal differences in precipitation (type, intensity, amount) and the emission source.

  16. The redox state of iron in the matrix of CI, CM and metamorphosed CM chondrites by XANES spectroscopy

    NASA Astrophysics Data System (ADS)

    Beck, P.; De Andrade, V.; Orthous-Daunay, F.-R.; Veronesi, G.; Cotte, M.; Quirico, E.; Schmitt, B.

    2012-12-01

    Carbonaceous chondrites record the action of water at some point of their petrological history. These meteorites are usually connected to low albedo asteroid, which present visible/near-IR absorption explained by iron related absorption within phyllosilicates and oxides. In order to obtain quantitative insight into the mineralogy of iron-bearing phases, we have measured X-ray absorption near-edge spectroscopy at the iron K-edge of matrix from carbonaceous chondrites. This method enables to constrain the redox state and environment of iron in these meteorites. For this study, we selected seven CM chondrites and the CI Orgueil, expected to span a range of aqueous alteration degrees. Our analysis of the pre-edge features show that the redox state of Orgueil (CI) is dominated by octahedral Fe and that the Fe3+/(Fe3++Fe2+) atomic ratio is above 80%. Full-inversion of the spectra suggests that the iron budget is dominated by iron oxides, with additional contributions from phyllosilicate. In the case of the CM, the iron speciation appears different that in the case of Orgueil. Cronstedtite is identified from the inversion of the spectra, and suggested by the presence of significant amount of tetrahedral Fe3+. Within the CM chondrites, a trend of aqueous alteration appears presents, and which is roughly correlated to the scheme defined by Rubin et al. (2007). This trend is characterized by an increase in the amount of iron oxides. Two shock metamorphosed CM are present in our dataset (PCA 91008, WIS 91600). If WIS 91600 does not appear distinguishable, from the CM trend, in the case of PCA 91008, shock metamorphism did impact the pre-edge intensity and an increased amount of anhydrous silicates is found. Although the matrix was dehydrated, significant amount of Fe3+ is still present, providing a memory of the aqueous alteration.

  17. Contribution of Lateral Column Lengthening to Correction of Forefoot Abduction in Stage IIb Adult Acquired Flatfoot Deformity Reconstruction.

    PubMed

    Chan, Jeremy Y; Greenfield, Stephen T; Soukup, Dylan S; Do, Huong T; Deland, Jonathan T; Ellis, Scott J

    2015-12-01

    Correction of forefoot abduction in stage IIb adult acquired flatfoot likely depends on the amount of lateral column lengthening (LCL) performed, although this represents only one aspect of a successful reconstruction. The purpose of this study was to evaluate the correlation between common reconstructive variables and the observed change in forefoot abduction. Forty-one patients who underwent flatfoot reconstruction involving an Evans-type LCL were assessed retrospectively. Preoperative and postoperative anteroposterior (AP) radiographs of the foot at a minimum of 40 weeks (mean, 2 years) after surgery were reviewed to determine correction in forefoot abduction as measured by talonavicular coverage (TNC) angle, talonavicular uncoverage percent, talus-first metatarsal (T-1MT) angle, and lateral incongruency angle. Fourteen demographic and intraoperative variables were evaluated for association with change in forefoot abduction including age, gender, height, weight, body mass index, as well as the amount of LCL and medializing calcaneal osteotomy performed, LCL graft type, Cotton osteotomy, first tarsometatarsal fusion, flexor digitorum longus transfer, spring ligament repair, gastrocnemius recession and any one of the modified McBride/Akin/Silver procedures. Two variables significantly affected the change in lateral incongruency angle. These were weight (P = .04) and the amount of LCL performed (P < .001). No variables were associated with the change in TNC angle, talonavicular uncoverage percent, or T-1MT angle. Multivariate regression analysis revealed that LCL was the only significant predictor of the change in lateral incongruency angle. The final regression model for LCL showed a good fit (R2 = 0.70, P < .001). Each millimeter of LCL corresponded to a 6.8-degree change in lateral incongruency angle. Correction of forefoot abduction in flatfoot reconstruction was primarily determined by the LCL procedure and could be modeled linearly. We believe that the lateral incongruency angle can serve as a valuable preoperative measurement to help surgeons titrate the proper amount of correction performed intraoperatively. © The Author(s) 2015.

  18. Sociodemographic and health characteristics, rather than primary care supply, are major drivers of geographic variation in preventable hospitalizations in Australia.

    PubMed

    Falster, Michael O; Jorm, Louisa R; Douglas, Kirsty A; Blyth, Fiona M; Elliott, Robert F; Leyland, Alastair H

    2015-05-01

    Geographic rates of preventable hospitalization are used internationally as an indicator of accessibility and quality of primary care. Much research has correlated the indicator with the supply of primary care services, yet multiple other factors may influence these admissions. To quantify the relative contributions of the supply of general practitioners (GPs) and personal sociodemographic and health characteristics, to geographic variation in preventable hospitalization. Self-reported questionnaire data for 267,091 participants in the 45 and Up Study, Australia, were linked with administrative hospital data to identify preventable hospitalizations. Multilevel Poisson models, with participants clustered in their geographic area of residence, were used to explore factors that explain geographic variation in hospitalization. GP supply, measured as full-time workload equivalents, was not a significant predictor of preventable hospitalization, and explained only a small amount (2.9%) of the geographic variation in hospitalization rates. Conversely, more than one-third (36.9%) of variation was driven by the sociodemographic composition, health, and behaviors of the population. These personal characteristics explained a greater amount of the variation for chronic conditions (37.5%) than acute (15.5%) or vaccine-preventable conditions (2.4%). Personal sociodemographic and health characteristics, rather than GP supply, are major drivers of preventable hospitalization. Their contribution varies according to condition, and if used for performance comparison purposes, geographic rates of preventable hospitalization should be reported according to individual condition or potential pathways for intervention.

  19. Sociodemographic and Health Characteristics, Rather Than Primary Care Supply, are Major Drivers of Geographic Variation in Preventable Hospitalizations in Australia

    PubMed Central

    Jorm, Louisa R.; Douglas, Kirsty A.; Blyth, Fiona M.; Elliott, Robert F.; Leyland, Alastair H.

    2015-01-01

    Background: Geographic rates of preventable hospitalization are used internationally as an indicator of accessibility and quality of primary care. Much research has correlated the indicator with the supply of primary care services, yet multiple other factors may influence these admissions. Objective: To quantify the relative contributions of the supply of general practitioners (GPs) and personal sociodemographic and health characteristics, to geographic variation in preventable hospitalization. Methods: Self-reported questionnaire data for 267,091 participants in the 45 and Up Study, Australia, were linked with administrative hospital data to identify preventable hospitalizations. Multilevel Poisson models, with participants clustered in their geographic area of residence, were used to explore factors that explain geographic variation in hospitalization. Results: GP supply, measured as full-time workload equivalents, was not a significant predictor of preventable hospitalization, and explained only a small amount (2.9%) of the geographic variation in hospitalization rates. Conversely, more than one-third (36.9%) of variation was driven by the sociodemographic composition, health, and behaviors of the population. These personal characteristics explained a greater amount of the variation for chronic conditions (37.5%) than acute (15.5%) or vaccine-preventable conditions (2.4%). Conclusions: Personal sociodemographic and health characteristics, rather than GP supply, are major drivers of preventable hospitalization. Their contribution varies according to condition, and if used for performance comparison purposes, geographic rates of preventable hospitalization should be reported according to individual condition or potential pathways for intervention. PMID:25793270

  20. Contributing Factors to Student Success in Anatomy and Physiology: Lower outside Workload and Better Preparation

    ERIC Educational Resources Information Center

    Harris, David E.; Hannum, Lynn; Gupta, Sat

    2004-01-01

    A study of students of a traditional two-semester Anatomy and Physiology class was made to determine factors that contributed to success in the coursework. The test established a co-relation between the amount of study in mathematics and science done previously in school and final grades in the subject.

  1. 26 CFR 1.401(a)(4)-2 - Nondiscrimination in amount of employer contributions under a defined contribution plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the allocation rates for the HCEs in the plan must not exceed the average of the allocation rates for the NHCEs in the plan. For this purpose, allocation rates are determined in accordance with paragraph (c)(2) of this section, without imputing permitted disparity and without grouping allocation rates...

  2. 26 CFR 1.401(a)(4)-2 - Nondiscrimination in amount of employer contributions under a defined contribution plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the allocation rates for the HCEs in the plan must not exceed the average of the allocation rates for the NHCEs in the plan. For this purpose, allocation rates are determined in accordance with paragraph (c)(2) of this section, without imputing permitted disparity and without grouping allocation rates...

  3. 26 CFR 1.401(a)(4)-2 - Nondiscrimination in amount of employer contributions under a defined contribution plan.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the allocation rates for the HCEs in the plan must not exceed the average of the allocation rates for the NHCEs in the plan. For this purpose, allocation rates are determined in accordance with paragraph (c)(2) of this section, without imputing permitted disparity and without grouping allocation rates...

  4. 26 CFR 1.118-1 - Contributions to the capital of a corporation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... through voluntary pro rata payments by its shareholders, the amounts so received being credited to its... individual shareholders, and will be treated as an addition to and as a part of the operating capital of the company. Section 118 also applies to contributions to capital made by persons other than shareholders. For...

  5. 26 CFR 54.4980G-5 - HSA comparability rules and cafeteria plans and waiver of excise tax.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... nondiscrimination rules (eligibility rules, contributions and benefits tests and key employee concentration tests... portion of the HSA contributions are available as pre-tax salary reduction amounts), regardless of whether... benefits tests and key employee concentration tests). See Q & A-1 of this section. Q-3: If under the...

  6. 45 CFR 33.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., overpayments, penalties, damages, interest, fines and forfeitures (except those arising under the Uniform Code... contributions. Amounts deducted under garnishment orders, including child support garnishment orders, are not...

  7. 45 CFR 33.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., overpayments, penalties, damages, interest, fines and forfeitures (except those arising under the Uniform Code... contributions. Amounts deducted under garnishment orders, including child support garnishment orders, are not...

  8. 45 CFR 33.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., overpayments, penalties, damages, interest, fines and forfeitures (except those arising under the Uniform Code... contributions. Amounts deducted under garnishment orders, including child support garnishment orders, are not...

  9. 45 CFR 33.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., overpayments, penalties, damages, interest, fines and forfeitures (except those arising under the Uniform Code... contributions. Amounts deducted under garnishment orders, including child support garnishment orders, are not...

  10. Chemical characteristics of ambient aerosols contributed by cooking process at Noorpur village near Delhi (India)

    NASA Astrophysics Data System (ADS)

    Singh, Sudha; Kumar, Bablu; Gupta, Gyan Prakash; Kulshrestha, U. C.

    2013-05-01

    Combustion of fuels such as wood, crop residue and dung cakes etc. is one of the major sources of air pollution in developing countries. These fuels are still used commonly for cooking purpose in rural India. This study investigates the chemical composition of the ambient aerosols during cooking hours at a village called Noorpur (28.470 N, 77.030 E) which lies near Delhi city. Aerosol sampling was carried out during August 2011-May 2012 by using handy sampler (Envirotech model APM 821) installed at the terrace of a building (˜6m). The samples were collected on 8 hourly basis using Teflon filters. The water extract of these filters was analyzed for major anions (F-, Cl-, NO3-, SO42-) and major cations (Na+, NH4+, K+, Ca2+ Mg2+) by ion chromatography (Metrohm 883 Basic IC Plus). Results highlighted that cooking process contributed significant amount of SO42- and K+ṡ. Biomass burning is considered as a potential source of K+ in air. The high concentration of SO42- might be due to oxidation of SO2 contributed by the combustion of dung cakes. Further, the detailed results will be discussed during the conference.

  11. Whole Grains Contribute Only a Small Proportion of Dietary Fiber to the U.S. Diet.

    PubMed

    Kranz, Sibylle; Dodd, Kevin W; Juan, Wen Yen; Johnson, LuAnn K; Jahns, Lisa

    2017-02-17

    Dietary fiber (DF), found in whole fruits, vegetables, and whole grains (WG), is considered a nutrient of concern in the US diet and increased consumption is recommended. The present study was designed to highlight this critical importance of the difference between WG, high-fiber WG, and sources of fiber that are not from WG. The study is based on the two-day diets reported consumed by the nationally representative sample of Americans participating in What We Eat In America, the dietary component of the National Health and Nutrition Examination Survey from 2003-2010. Foods consumed were classified into tertiles of DF and WG and the contribution of fiber by differing levels of WG content were examined. Foods containing high amounts of WG and DF only contributed about 7% of total fiber intake. Overall, grain-based foods contributed 54.5% of all DF consumed. Approximately 39% of DF came from grain foods that contained no WG, rather these foods contained refined grains, which contain only small amounts of DF but are consumed in large quantities. All WG-containing foods combined contributed a total of 15.3% of DF in the American diet. Thus, public health messaging needs to be changed to specifically encourage consumption of WG foods with high levels of DF to address both recommendations.

  12. Greater soil carbon accumulation in deeper soils in native- than in exotic-dominated grassland plantings in the southern Plains

    NASA Astrophysics Data System (ADS)

    Wilsey, B. J.; Xu, X.; Polley, H. W.; Hofmockel, K. S.

    2017-12-01

    Global change includes invasion by non-native plant species, and invasion may affect carbon cycling and storage. We tested predictions in central Texas in an experiment that compares mixtures of all exotic or all native species under two summer irrigation treatments (128 or 0 mm) that varies the amount of summer drought stress. At the end of the eighth growing season after establishment, soils were sampled in 10 cm increments to 100 cm depth to determine if soil C differed among treatments, and if treatments differentially affected soil C in deeper soils. Soil C content was significantly (5%) higher under native plantings than under exotic species plantings (P < 0.001). The difference between native and exotic plantings increased with depth, and native plantings had higher soil C in deeper soil layers than in surface layers (native-exotic x depth, P < 0.001). Exotic plantings had decreasing soil C with depth. Soil C:N ratio and δ13C/12C were also significantly affected by native-exotic status, with soils in exotic plots having a significantly greater C4 contribution than native soils. Soil C was unaffected by summer irrigation treatments. Our results suggest that a significant amount of carbon could be sequestered by replacing exotic plant species with native species in the southern Plains, and that more work should be conducted at deeper soil depths. If we had restricted our analyses to surface soil layers (e.g. top 30 cm), we would have failed to detect depth differences between natives and exotics.

  13. Forefoot-rearfoot coupling patterns and tibial internal rotation during stance phase of barefoot versus shod running.

    PubMed

    Eslami, Mansour; Begon, Mickaël; Farahpour, Nader; Allard, Paul

    2007-01-01

    Based on twisted plate and mitered hinge models of the foot and ankle, forefoot-rearfoot coupling motion patterns can contribute to the amount of tibial rotation. The present study determined the differences of forefoot-rearfoot coupling patterns as well as excessive excursion of tibial internal rotation in shod versus barefoot conditions during running. Sixteen male subjects ran 10 times at 170 steps per minute under the barefoot and shod conditions. Forefoot-rearfoot coupling motions were assessed by measuring mean relative phase angle during five intervals of stance phase for the main effect of five time intervals and two conditions (ANOVA, P<0.05). Tibial internal rotation excursion was compared between the shod and barefoot conditions over the first 50% of stance phase using paired t-test, (P<0.05). Forefoot adduction/abduction and rearfoot eversion/inversion coupling motion patterns were significantly different between the conditions and among the intervals (P<0.05; effect size=0.47). The mean absolute relative angle was significantly modified to 37 degrees in-phase relationship at the heel-strike of running with shoe wears. No significant differences were noted in the tibial internal rotation excursion between shod and barefoot conditions. Significant variations in the forefoot adduction/abduction and rearfoot eversion/inversion coupling patterns could have little effect on the amount of tibial internal rotation excursion. Yet it remains to be determined whether changes in the frontal plane forefoot-rearfoot coupling patterns influence the tibia kinematics for different shoe wears or foot orthotic interventions. The findings question the rational for the prophylactic use of forefoot posting in foot orthoses.

  14. Comparative trial of Aloe vera/olive oil combination cream versus phenytoin cream in the treatment of chronic wounds.

    PubMed

    Panahi, Y; Izadi, M; Sayyadi, N; Rezaee, R; Jonaidi-Jafari, N; Beiraghdar, F; Zamani, A; Sahebkar, A

    2015-10-01

    Aloe vera is a medicinal plant that has been traditionally used to accelerate wound healing. Olive oil is also a natural product that may contribute to wound healing owing to its antimicrobial and anti-inflammatory effects. The present study aimed to evaluate the effect of an Aloe vera-olive oil (AVO) combination cream on the healing process of chronic wounds. In this randomised, double-blind, comparator-controlled, parallel-group trial, patients with chronic wounds were treated with either AVO cream or phenytoin cream as the standard treatment for a period of 30 days. Wound healing was evaluated using Bates-Jensen assessment tool and the severity of pain was assessed using a visual analogue scale (VAS). After initial assessment, 60 patients with chronic wounds (41 with pressure ulcer, 13 with diabetic wounds and 6 with venous ulcers), were recruited and randomised into 2 groups of 30. After 30 days of treatment, significant improvements in the wound size, depth, and edges; necrotic tissue type and amount; exudate type and amount; colour of wound surroundings; and peripheral tissue oedema score were observed in the AVO cream group (p<0.001). The total score of wound healing showed significant improvement with both AVO (p<0.001) and phenytoin (p<0.01) creams, although AVO was more efficacious (p<0.001). Likewise, although both treatments reduced the initial VAS score, the efficacy of AVO was significantly greater (p<0.001). AVO cream significantly accelerates biological healing of chronic wounds and helps to reduce pain severity with a higher efficacy compared with phenytoin cream.

  15. Production of nitric oxide by peripheral blood mononuclear cells from the Florida manatee, Trichechus manatus latirostris.

    PubMed

    Walsh, Catherine J; Stuckey, Joyce E; Cox, Heather; Smith, Brett; Funke, Christina; Stott, Jeff; Colle, Clarence; Gaspard, Joseph; Manire, Charles A

    2007-08-15

    Florida manatees (Trichechus manatus latirostris) are exposed to many conditions in their habitat that may adversely impact health and impair immune function in this endangered species. In an effort to increase the current knowledge base regarding the manatee immune system, the production of an important reactive nitrogen intermediate, nitric oxide (NO), by manatee peripheral blood mononuclear cells (PBMC) was investigated. PBMC from healthy captive manatees were stimulated with LPS, IFN-gamma, or TNF-alpha, either alone or in various combinations, with NO production assessed after 24, 48, 72, and 96 h of culture. NO production in response to LPS stimulation was significantly greater after 48, 72, or 96 h of culture compared to NO production after 24h of culture. A specific inhibitor of inducible nitric oxide synthase (iNOS), L-NIL (L-N(6)-(1-iminoethyl)lysine), significantly decreased NO production by LPS-stimulated manatee PBMC. Manatee specific oligonucleotide primers for iNOS were designed to measure expression of relative amounts of mRNA in LPS-stimulated manatee PBMC from captive manatees. NO production by PBMC from manatees exposed to red tide toxins was analyzed, with significantly greater NO production by both unstimulated and LPS stimulated PBMC from red tide exposed compared with healthy captive or cold-stress manatees. Free-ranging manatees produced significantly lower amounts of nitric oxide compared to either captive or red tide rescued manatees. Results presented in this paper contribute to the current understanding of manatee immune function and represent the first report of nitric oxide production in the immune system of a marine mammal.

  16. Bianchi I cosmology in the presence of a causally regularized viscous fluid

    NASA Astrophysics Data System (ADS)

    Montani, Giovanni; Venanzi, Marta

    2017-07-01

    We analyze the dynamics of a Bianchi I cosmology in the presence of a viscous fluid, causally regularized according to the Lichnerowicz approach. We show how the effect induced by shear viscosity is still able to produce a matter creation phenomenon, meaning that also in the regularized theory we address, the Universe is emerging from a singularity with a vanishing energy density value. We discuss the structure of the singularity in the isotropic limit, when bulk viscosity is the only retained contribution. We see that, as far as viscosity is not a dominant effect, the dynamics of the isotropic Universe possesses the usual non-viscous power-law behaviour but in correspondence to an effective equation of state, depending on the bulk viscosity coefficient. Finally, we show that, in the limit of a strong non-thermodynamical equilibrium of the Universe mimicked by a dominant contribution of the effective viscous pressure, a power-law inflation behaviour of the Universe appears, the cosmological horizons are removed and a significant amount of entropy is produced.

  17. Phenolic acids and methylxanthines composition and antioxidant properties of mate (Ilex paraguariensis) residue.

    PubMed

    Vieira, Manoela A; Maraschin, Marcelo; Pagliosa, Cristiane M; Podestá, Rossana; de Simas, Karina N; Rockenbach, Ismael Ivan; Amboni, Renata D de M C; Amante, Edna R

    2010-04-01

    Ilex paraguariensis is known to contain compounds with antioxidant properties, such as phenolic acids, and its stimulant properties are attributed to methylxanthines, such as caffeine. The aims of this study were to evaluate the phenolic, methylxanthinic, and tannin composition of a mate residue (mate powder), to compare the quali-quantitative phenolic composition and the antioxidant potential of extracts obtained from distinct solvent systems. Among the extracts prepared with different solvents, the 80% methanol extract showed the highest total polyphenol content (11.51 g/100 g) and antioxidant activity. HPLC analysis showed that 4,5 dicaffeoylquinic acid is the major component of the phenolic fraction of mate powder. The caffeine, theobromine, and tannin contents in mate powder were 1.01, 0.10, and 0.29 g/100 g, respectively. Consumption of mate powder would significantly contribute to antioxidant and stimulant intake, providing high amounts of phenolic acids, tannins, and methylxanthines with biological effects potentially beneficial for human health. This article contributes to the minimization of residues in yerba-mate processing.

  18. Knowledge discovery for pancreatic cancer using inductive logic programming.

    PubMed

    Qiu, Yushan; Shimada, Kazuaki; Hiraoka, Nobuyoshi; Maeshiro, Kensei; Ching, Wai-Ki; Aoki-Kinoshita, Kiyoko F; Furuta, Koh

    2014-08-01

    Pancreatic cancer is a devastating disease and predicting the status of the patients becomes an important and urgent issue. The authors explore the applicability of inductive logic programming (ILP) method in the disease and show that the accumulated clinical laboratory data can be used to predict disease characteristics, and this will contribute to the selection of therapeutic modalities of pancreatic cancer. The availability of a large amount of clinical laboratory data provides clues to aid in the knowledge discovery of diseases. In predicting the differentiation of tumour and the status of lymph node metastasis in pancreatic cancer, using the ILP model, three rules are developed that are consistent with descriptions in the literature. The rules that are identified are useful to detect the differentiation of tumour and the status of lymph node metastasis in pancreatic cancer and therefore contributed significantly to the decision of therapeutic strategies. In addition, the proposed method is compared with the other typical classification techniques and the results further confirm the superiority and merit of the proposed method.

  19. The Outsized Influence of a Primordial Lunar Atmosphere

    NASA Astrophysics Data System (ADS)

    Saxena, Prabal; Elkins-Tanton, Linda T.; Petro, Noah; Mandell, Avi

    2016-10-01

    Immediately following formation of the moon, its surface was subject to radiative influences from the Lunar Magma Ocean, an early Earth that radiated like a mid type M Dwarf Star, and the early Sun. These contributions have been hypothesized to have produced a vapor pressure atmosphere on the Moon. We model the early atmosphere of the Moon using an atmospheric model originally developed for Io. We also use a magma ocean crystallization model that finds that heating from the early Earth delays crystallization of the Lunar Magma Ocean and contributes to a moderate pressure and collapsing metal-dominated atmosphere on the earthside of the Moon until lid formation. The atmosphere is characterized by maximum pressures ~1 bar and strong horizontal supersonic winds that decreased as the Moon's orbital separation increased. Crustal and other compositional asymmetries may have been influenced by this atmosphere. The atmosphere transported significant amounts of mass horizontally and may have been a source for present day depletions and heterogeneities of moderately volatile elements on the lunar surface.

  20. Tobacco Industry Influences in the Oklahoma Legislature.

    PubMed

    Matheny, James D; Wagener, Theodore L; Anderson, Michael P

    2015-11-01

    To identify recent tobacco industry influences in the Oklahoma Legislature. Relevant public records were compiled and published online in searchable databases. Activities related to two contested tobacco-related legislative initiatives were analyzed. Analyses of voting behavior controlled for party affiliation. Legislators receiving the largest amounts of campaign contributions and gifts from tobacco lobbyists performed actions necessary to advance tobacco industry objectives. Several significant associations with voting behavior were observed, the strongest of which was between votes on a pro-tobacco industry bill and gifts from tobacco lobbyists. Most lobbyists'gifts were meals. Tobacco industry influence in the Oklahoma Legislature is enhanced through tobacco lobbyists' campaign contributions and gifts. Greater investments are made in legislative leaders, those serving as champions or spokespersons, and others taking key roles in advancing tobacco industry objectives. Exposing such influences may diminish their effects. Given the egregious and uniquely destructive behavior of the tobacco industry, lawmakers could, as an ethical matter of principle, refuse tobacco lobbyists' money and seek to remedy past harms.

  1. Development of a Polysilicon Process Based on Chemical Vapor Deposition of Dichlorosilane in an Advanced Siemen's Reactor

    NASA Technical Reports Server (NTRS)

    Arevidson, A. N.; Sawyer, D. H.; Muller, D. M.

    1983-01-01

    Dichlorosilane (DCS) was used as the feedstock for an advanced decomposition reactor for silicon production. The advanced reactor had a cool bell jar wall temperature, 300 C, when compared to Siemen's reactors previously used for DCS decomposition. Previous reactors had bell jar wall temperatures of approximately 750 C. The cooler wall temperature allows higher DCS flow rates and concentrations. A silicon deposition rate of 2.28 gm/hr-cm was achieved with power consumption of 59 kWh/kg. Interpretation of data suggests that a 2.8 gm/hr-cm deposition rate is possible. Screening of lower cost materials of construction was done as a separate program segment. Stainless Steel (304 and 316), Hastalloy B, Monel 400 and 1010-Carbon Steel were placed individually in an experimental scale reactor. Silicon was deposited from trichlorosilane feedstock. The resultant silicon was analyzed for electrically active and metallic impurities as well as carbon. No material contributed significant amounts of electrically active or metallic impurities, but all contributed carbon.

  2. Significance of auditory and kinesthetic feedback to singers' pitch control.

    PubMed

    Mürbe, Dirk; Pabst, Friedemann; Hofmann, Gert; Sundberg, Johan

    2002-03-01

    An accurate control of fundamental frequency (F0) is required from singers. This control relies on auditory and kinesthetic feedback. However, a loud accompaniment may mask the auditory feedback, leaving the singers to rely on kinesthetic feedback. The object of the present study was to estimate the significance of auditory and kinesthetic feedback to pitch control in 28 students beginning a professional solo singing education. The singers sang an ascending and descending triad pattern covering their entire pitch range with and without masking noise in legato and staccato and in a slow and a fast tempo. F0 was measured by means of a computer program. The interval sizes between adjacent tones were determined and their departures from equally tempered tuning were calculated. The deviations from this tuning were used as a measure of the accuracy of intonation. Statistical analysis showed a significant effect of masking that amounted to a mean impairment of pitch accuracy by 14 cent across all subjects. Furthermore, significant effects were found of tempo as well as of the staccato/legato conditions. The results indicate that auditory feedback contributes significantly to singers' control of pitch.

  3. Catabolism of Branched Chain Amino Acids Contributes Significantly to Synthesis of Odd-Chain and Even-Chain Fatty Acids in 3T3-L1 Adipocytes.

    PubMed

    Crown, Scott B; Marze, Nicholas; Antoniewicz, Maciek R

    2015-01-01

    The branched chain amino acids (BCAA) valine, leucine and isoleucine have been implicated in a number of diseases including obesity, insulin resistance, and type 2 diabetes mellitus, although the mechanisms are still poorly understood. Adipose tissue plays an important role in BCAA homeostasis by actively metabolizing circulating BCAA. In this work, we have investigated the link between BCAA catabolism and fatty acid synthesis in 3T3-L1 adipocytes using parallel 13C-labeling experiments, mass spectrometry and model-based isotopomer data analysis. Specifically, we performed parallel labeling experiments with four fully 13C-labeled tracers, [U-13C]valine, [U-13C]leucine, [U-13C]isoleucine and [U-13C]glutamine. We measured mass isotopomer distributions of fatty acids and intracellular metabolites by GC-MS and analyzed the data using the isotopomer spectral analysis (ISA) framework. We demonstrate that 3T3-L1 adipocytes accumulate significant amounts of even chain length (C14:0, C16:0 and C18:0) and odd chain length (C15:0 and C17:0) fatty acids under standard cell culture conditions. Using a novel GC-MS method, we demonstrate that propionyl-CoA acts as the primer on fatty acid synthase for the production of odd chain fatty acids. BCAA contributed significantly to the production of all fatty acids. Leucine and isoleucine contributed at least 25% to lipogenic acetyl-CoA pool, and valine and isoleucine contributed 100% to lipogenic propionyl-CoA pool. Our results further suggest that low activity of methylmalonyl-CoA mutase and mass action kinetics of propionyl-CoA on fatty acid synthase result in high rates of odd chain fatty acid synthesis in 3T3-L1 cells. Overall, this work provides important new insights into the connection between BCAA catabolism and fatty acid synthesis in adipocytes and underscores the high capacity of adipocytes for metabolizing BCAA.

  4. The prevalence of upright non-stepping time in comparison to stepping time in 11-13 year old school children across seasons.

    PubMed

    McCrorie, P Rw; Duncan, E; Granat, M H; Stansfield, B W

    2012-11-01

    Evidence suggests that behaviours such as standing are beneficial for our health. Unfortunately, little is known of the prevalence of this state, its importance in relation to time spent stepping or variation across seasons. The aim of this study was to quantify, in young adolescents, the prevalence and seasonal changes in time spent upright and not stepping (UNSt(time)) as well as time spent upright and stepping (USt(time)), and their contribution to overall upright time (U(time)). Thirty-three adolescents (12.2 ± 0.3 y) wore the activPAL activity monitor during four school days on two occasions: November/December (winter) and May/June (summer). UNSt(time) contributed 60% of daily U(time) at winter (Mean = 196 min) and 53% at summer (Mean = 171 min); a significant seasonal effect, p < 0.001. USt(time) was significantly greater in summer compared to winter (153 min versus 131 min, p < 0.001). The effects in UNSt(time) could be explained through significant seasonal differences during the school hours (09:00-16:00), whereas the effects in USt(time) could be explained through significant seasonal differences in the evening period (16:00-22:00). Adolescents spent a greater amount of time upright and not stepping than they did stepping, in both winter and summer. The observed seasonal effects for both UNSt(time) and USt(time) provide important information for behaviour change intervention programs.

  5. A pilot study on nicotine residues in houses of electronic cigarette users, tobacco smokers, and non-users of nicotine-containing products.

    PubMed

    Bush, Derek; Goniewicz, Maciej L

    2015-06-01

    Nicotine deposited on the surfaces has been shown to react with airborne chemicals leading to formation of carcinogens and contributing to thirdhand exposure. While prior studies revealed nicotine residues in tobacco smokers' homes, none have examined the nicotine residue in electronic cigarette (e-cigarette) users' homes. We measured nicotine on the surfaces in households of 8 e-cigarette users, 6 cigarette smokers, and 8 non-users of nicotine-containing products in Western New York, USA. Three surface wipe samples were taken from the floor, wall and window. Nicotine was extracted from the wipes and analyzed using gas chromatography. Half of the e-cigarette users' homes had detectable levels of nicotine on surfaces whereas nicotine was found in all of the tobacco cigarette smokers' homes. Trace amounts of nicotine were also detected in half of the homes of non-users of nicotine-containing products. Nicotine levels in e-cigarette users homes was significantly lower than that found in cigarette smokers homes (average concentration 7.7±17.2 vs. 1303±2676 μg/m2; p<0.05). There was no significant difference in the amount of nicotine in homes of e-cigarette users and non-users (p>0.05). Nicotine is a common contaminant found on indoor surfaces. Using e-cigarettes indoors leads to significantly less thirdhand exposure to nicotine compared to smoking tobacco cigarettes. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Willingness to pay for health insurance among the elderly population in Germany.

    PubMed

    Bock, Jens-Oliver; Heider, Dirk; Matschinger, Herbert; Brenner, Hermann; Saum, Kai-Uwe; Haefeli, Walter E; König, Hans-Helmut

    2016-03-01

    All elderly Germans are legally obliged to have health insurance. About 90 % of this population are members of social health insurances (SHI) whose premiums are generally income-related and independent of health status. For most of these members, holding social health insurance is mandatory. As a consequence, genuine information about preferences for health insurance is not available. The aim of this study was therefore to determine and analyze the willingness to pay (WTP) for health insurance among elderly Germans. Data from a population-based 8-year follow-up of a large cohort study conducted in the Saarland, Germany was used. Participants aged 57-84 years passed a geriatric assessment and responded to a health economic questionnaire. Individuals' WTP was elicited based on a contingent valuation method with a payment card. Mean monthly WTP per capita for health insurance amounted to €260. This corresponded to about 20% of individual disposable income. Regression analyses showed that WTP increased significantly with higher income, male gender, higher educational level, and privately insured status. In contrast, neither increasing morbidity level nor higher individual health care costs influenced WTP significantly. The relatively large extent of average WTP for health insurance indicates that the elderly would probably accept higher contributions to SHI rather than policy efforts to reduce contributions. The identified determinants of WTP might indicate that elderly generally approve the principle of solidarity of the SHI with contributions depending on income rather than morbidity.

  7. Source Apportionment and Elemental Composition of PM2.5 and PM10 in Jeddah City, Saudi Arabia.

    PubMed

    Khodeir, Mamdouh; Shamy, Magdy; Alghamdi, Mansour; Zhong, Mianhua; Sun, Hong; Costa, Max; Chen, Lung-Chi; Maciejczyk, Polina

    2012-07-01

    This paper presents the first comprehensive investigation of PM2.5 and PM10 composition and sources in Saudi Arabia. We conducted a multi-week multiple sites sampling campaign in Jeddah between June and September, 2011, and analyzed samples by XRF. The overall mean mass concentration was 28.4 ± 25.4 μg/m 3 for PM2.5 and 87.3 ± 47.3 μg/m 3 for PM10, with significant temporal and spatial variability. The average ratio of PM2.5/PM10 was 0.33. Chemical composition data were modeled using factor analysis with varimax orthogonal rotation to determine five and four particle source categories contributing significant amount of for PM2.5 and PM10 mass, respectively. In both PM2.5 and PM10 sources were (1) heavy oil combustion characterized by high Ni and V; (2) resuspended soil characterized by high concentrations of Ca, Fe, Al, and Si; and (3) marine aerosol. The two other sources in PM2.5 were (4) Cu/Zn source; (5) traffic source identified by presence of Pb, Br, and Se; while in PM10 it was a mixed industrial source. To estimate the mass contributions of each individual source category, the CAPs mass concentration was regressed against the factor scores. Cumulatively, resuspended soil and oil combustion contributed 77 and 82% mass of PM2.5 and PM10, respectively.

  8. Source Apportionment and Elemental Composition of PM2.5 and PM10 in Jeddah City, Saudi Arabia

    PubMed Central

    Khodeir, Mamdouh; Shamy, Magdy; Alghamdi, Mansour; Zhong, Mianhua; Sun, Hong; Costa, Max; Chen, Lung-Chi; Maciejczyk, Polina

    2014-01-01

    This paper presents the first comprehensive investigation of PM2.5 and PM10 composition and sources in Saudi Arabia. We conducted a multi-week multiple sites sampling campaign in Jeddah between June and September, 2011, and analyzed samples by XRF. The overall mean mass concentration was 28.4 ± 25.4 μg/m3 for PM2.5 and 87.3 ± 47.3 μg/m3 for PM10, with significant temporal and spatial variability. The average ratio of PM2.5/PM10 was 0.33. Chemical composition data were modeled using factor analysis with varimax orthogonal rotation to determine five and four particle source categories contributing significant amount of for PM2.5 and PM10 mass, respectively. In both PM2.5 and PM10 sources were (1) heavy oil combustion characterized by high Ni and V; (2) resuspended soil characterized by high concentrations of Ca, Fe, Al, and Si; and (3) marine aerosol. The two other sources in PM2.5 were (4) Cu/Zn source; (5) traffic source identified by presence of Pb, Br, and Se; while in PM10 it was a mixed industrial source. To estimate the mass contributions of each individual source category, the CAPs mass concentration was regressed against the factor scores. Cumulatively, resuspended soil and oil combustion contributed 77 and 82% mass of PM2.5 and PM10, respectively. PMID:24634602

  9. Estimating wetland connectivity to streams in the Prairie Pothole Region: An isotopic and remote sensing approach

    USGS Publications Warehouse

    Brooks, J. R.; Mushet, David M.; Vanderhoof, Melanie; Leibowitz, Scott G.; Neff, Brian; Christensen, J. R.; Rosenberry, Donald O.; Rugh, W. D.; Alexander, L.C.

    2018-01-01

    Understanding hydrologic connectivity between wetlands and perennial streams is critical to understanding the reliance of stream flow on inputs from wetlands. We used the isotopic evaporation signal in water and remote sensing to examine wetland‐stream hydrologic connectivity within the Pipestem Creek watershed, North Dakota, a watershed dominated by prairie‐pothole wetlands. Pipestem Creek exhibited an evaporated‐water signal that had approximately half the isotopic‐enrichment signal found in most evaporatively enriched prairie‐pothole wetlands. Groundwater adjacent to Pipestem Creek had isotopic values that indicated recharge from winter precipitation and had no significant evaporative enrichment, indicating that enriched surface water did not contribute significantly to groundwater discharging into Pipestem Creek. The estimated surface water area necessary to generate the evaporation signal within Pipestem Creek was highly dynamic, varied primarily with the amount of discharge, and was typically greater than the immediate Pipestem Creek surface water area, indicating that surficial flow from wetlands contributed to stream flow throughout the summer. We propose a dynamic range of spilling thresholds for prairie‐pothole wetlands across the watershed allowing for wetland inputs even during low‐flow periods. Combining Landsat estimates with the isotopic approach allowed determination of potential (Landsat) and actual (isotope) contributing areas in wetland‐dominated systems. This combined approach can give insights into the changes in location and magnitude of surface water and groundwater pathways over time. This approach can be used in other areas where evaporation from wetlands results in a sufficient evaporative isotopic signal.

  10. Potential Angiogenic Role of Platelet-Activating Factor in Human Breast Cancer

    PubMed Central

    Montrucchio, Giuseppe; Sapino, Anna; Bussolati, Benedetta; Ghisolfi, Gianpiero; Rizea-Savu, Simona; Silvestro, Luigi; Lupia, Enrico; Camussi, Giovanni

    1998-01-01

    This study investigated the presence of platelet-activating factor (PAF) in the lipid extracts of 18 primary breast carcinomas and 20 control breast tissues. The amount of PAF detected in breast carcinomas was significantly higher than in controls. The mass spectrometric analysis of PAF-bioactive lipid extract from breast carcinomas showed the presence of several molecular species of PAF, including C16-alkylPAF, C18-lysophosphatidylcholine (LPC), C16-LPC, lyso-PAF, and C16-acylPAF. The amount of bioactive PAF extracted from breast specimens significantly correlated with tumor vascularization revealed by the number of CD34- and CD31-positive cells. As C16-alkylPAF was previously shown to induce angiogenesis in vivo, we evaluated whether the thin layer chromatography-purified lipid extracts of breast specimens elicited neoangiogenesis in a murine model of subcutaneous Matrigel injection. The lipid extracts from specimens of breast carcinoma containing high levels of PAF bioactivity, but not from breast carcinomas containing low levels of PAF bioactivity or from normal breast tissue, induced a significant angiogenic response. This angiogenic response was significantly inhibited by the PAF receptor antagonist WEB 2170. T47D and MCF7 breast cancer cell lines, but not an immortalized nontumor breast cell line (MCF10), released PAF in the culture medium. A significant in vivo neoangiogenic response, inhibited by WEB 2170, was elicited by T47D and MCF7 but not by MCF10 culture medium. These results indicate that an increased concentration of PAF is present in tumors with high microvessel density and that PAF may account for the neoangiogenic activity induced in mice by the lipid extracts obtained from breast cancer. A contribution of PAF in the neovascularization of human breast cancer is suggested. PMID:9811351

  11. Comparison of Submicron Particles at a Rural and an Urban Site in the North China Plain during the December 2016 Heavy Pollution Episodes

    NASA Astrophysics Data System (ADS)

    Shen, Xiaojing; Sun, Junying; Zhang, Xiaoye; Zhang, Yangmei; Wang, Yaqiang; Tan, Kaiyan; Wang, Peng; Zhang, Lu; Qi, Xuefei; Che, Haochi; Zhang, Zhouxiang; Zhong, Junting; Zhao, Huarong; Ren, Sanxue

    2018-02-01

    An extensive field experiment for measurement of physical and chemical properties of aerosols was conducted at an urban site in the Chinese Academy of Meteorological Sciences (CAMS) in Beijing and at a rural site in Gucheng (GC), Hebei Province in December 2016. This paper compares the number size distribution of submicron particle matter (PM1, diameter < 1 μm) between the two sites. The results show that the mean PM1 number concentration at GC was twice that at CAMS, and the mass concentration was three times the amount at CAMS. It is found that the accumulation mode (100-850 nm) particles constituted the largest fraction of PM1 at GC, which was significantly correlated with the local coal combustion, as confirmed by a significant relationship between the accumulation mode and the absorption coefficient of soot particles. The high PM1 concentration at GC prevented the occurrence of new particle formation (NPF) events, while eight such events were observed at CAMS. During the NPF events, the mass fraction of sulfate increased significantly, indicating that sulfate played an important role in NPF. The contribution of regional transport to PM1 mass concentration was approximately 50% at both sites, same as that of the local emission. However, during the red-alert period when emission control took place, the contribution of regional transport was notably higher.

  12. Relative Bioavailability of Iron in Bangladeshi Traditional Meals Prepared with Iron-Fortified Lentil Dal

    PubMed Central

    Podder, Rajib; M. DellaValle, Diane; T. Tyler, Robert; P. Glahn, Raymond; Tako, Elad; Vandenberg, Albert

    2018-01-01

    Due to low Fe bioavailability and low consumption per meal, lentil must be fortified to contribute significant bioavailable Fe in the Bangladeshi diet. Moreover, since red lentil is dehulled prior to consumption, an opportunity exists at this point to fortify lentil with Fe. Thus, in the present study, lentil was Fe-fortified (using a fortificant Fe concentration of 2800 µg g−1) and used in 30 traditional Bangladeshi meals with broad differences in concentrations of iron, phytic acid (PA), and relative Fe bioavailability (RFeB%). Fortification with NaFeEDTA increased the iron concentration in lentil from 60 to 439 µg g−1 and resulted in a 79% increase in the amount of available Fe as estimated by Caco-2 cell ferritin formation. Phytic acid levels were reduced from 6.2 to 4.6 mg g−1 when fortified lentil was added, thereby reducing the PA:Fe molar ratio from 8.8 to 0.9. This effect was presumably due to dephytinization of fortified lentil during the fortification process. A significant (p ≤ 0.01) Pearson correlation was observed between Fe concentration and RFeB% and between RFeB% and PA:Fe molar ratio in meals with fortified lentil, but not for the meal with unfortified lentil. In conclusion, fortified lentil can contribute significant bioavailable Fe to populations at risk of Fe deficiency. PMID:29543712

  13. Relative Bioavailability of Iron in Bangladeshi Traditional Meals Prepared with Iron-Fortified Lentil Dal.

    PubMed

    Podder, Rajib; M DellaValle, Diane; T Tyler, Robert; P Glahn, Raymond; Tako, Elad; Vandenberg, Albert

    2018-03-15

    Due to low Fe bioavailability and low consumption per meal, lentil must be fortified to contribute significant bioavailable Fe in the Bangladeshi diet. Moreover, since red lentil is dehulled prior to consumption, an opportunity exists at this point to fortify lentil with Fe. Thus, in the present study, lentil was Fe-fortified (using a fortificant Fe concentration of 2800 µg g -1 ) and used in 30 traditional Bangladeshi meals with broad differences in concentrations of iron, phytic acid (PA), and relative Fe bioavailability (RFeB%). Fortification with NaFeEDTA increased the iron concentration in lentil from 60 to 439 µg g -1 and resulted in a 79% increase in the amount of available Fe as estimated by Caco-2 cell ferritin formation. Phytic acid levels were reduced from 6.2 to 4.6 mg g -1 when fortified lentil was added, thereby reducing the PA:Fe molar ratio from 8.8 to 0.9. This effect was presumably due to dephytinization of fortified lentil during the fortification process. A significant ( p ≤ 0.01) Pearson correlation was observed between Fe concentration and RFeB% and between RFeB% and PA:Fe molar ratio in meals with fortified lentil, but not for the meal with unfortified lentil. In conclusion, fortified lentil can contribute significant bioavailable Fe to populations at risk of Fe deficiency.

  14. Simulated use and wash-off release of decamethylcyclopentasiloxane used in anti-perspirants.

    PubMed

    Gouin, Todd; van Egmond, Roger; Sparham, Chris; Hastie, Colin; Chowdhury, Namrata

    2013-10-01

    The cyclic volatile methylsiloxane, decamethylcyclopentasiloxane (D5) is used in a large variety of personal care products. Based on the physical-chemical properties of D5, it is likely that losses due to volatilisation may strongly influence the levels entering the aquatic environment. The aim of this study was to quantify the amount of D5 in waste wash water, after typical application and use in a range of deodorant and anti-perspirant (AP) products. Results implied significant losses after a 24h period (>99.9%), and suggest that the use of D5 in leave-on products, such as deodorants/AP is not likely to contribute a significant down-the-drain emission source. An illustrative example is presented, based on data reporting the use of D5 in a range of personal care products (both wash-off and leave-on), which suggests that the contribution of D5 used in wash-off products to the aquatic environment may be considerably more significant. Limitations associated with our understanding of the actual D5 inclusion levels in the products, the market share of the products containing D5, and the variability of consumer habits, are identified as data gaps that need to be addressed in order to better refine down-the-drain emission estimates. Copyright © 2012 Elsevier Ltd. All rights reserved.

  15. OMIT: dynamic, semi-automated ontology development for the microRNA domain.

    PubMed

    Huang, Jingshan; Dang, Jiangbo; Borchert, Glen M; Eilbeck, Karen; Zhang, He; Xiong, Min; Jiang, Weijian; Wu, Hao; Blake, Judith A; Natale, Darren A; Tan, Ming

    2014-01-01

    As a special class of short non-coding RNAs, microRNAs (a.k.a. miRNAs or miRs) have been reported to perform important roles in various biological processes by regulating respective target genes. However, significant barriers exist during biologists' conventional miR knowledge discovery. Emerging semantic technologies, which are based upon domain ontologies, can render critical assistance to this problem. Our previous research has investigated the construction of a miR ontology, named Ontology for MIcroRNA Target Prediction (OMIT), the very first of its kind that formally encodes miR domain knowledge. Although it is unavoidable to have a manual component contributed by domain experts when building ontologies, many challenges have been identified for a completely manual development process. The most significant issue is that a manual development process is very labor-intensive and thus extremely expensive. Therefore, we propose in this paper an innovative ontology development methodology. Our contributions can be summarized as: (i) We have continued the development and critical improvement of OMIT, solidly based on our previous research outcomes. (ii) We have explored effective and efficient algorithms with which the ontology development can be seamlessly combined with machine intelligence and be accomplished in a semi-automated manner, thus significantly reducing large amounts of human efforts. A set of experiments have been conducted to thoroughly evaluate our proposed methodology.

  16. OMIT: Dynamic, Semi-Automated Ontology Development for the microRNA Domain

    PubMed Central

    Huang, Jingshan; Dang, Jiangbo; Borchert, Glen M.; Eilbeck, Karen; Zhang, He; Xiong, Min; Jiang, Weijian; Wu, Hao; Blake, Judith A.; Natale, Darren A.; Tan, Ming

    2014-01-01

    As a special class of short non-coding RNAs, microRNAs (a.k.a. miRNAs or miRs) have been reported to perform important roles in various biological processes by regulating respective target genes. However, significant barriers exist during biologists' conventional miR knowledge discovery. Emerging semantic technologies, which are based upon domain ontologies, can render critical assistance to this problem. Our previous research has investigated the construction of a miR ontology, named Ontology for MIcroRNA Target Prediction (OMIT), the very first of its kind that formally encodes miR domain knowledge. Although it is unavoidable to have a manual component contributed by domain experts when building ontologies, many challenges have been identified for a completely manual development process. The most significant issue is that a manual development process is very labor-intensive and thus extremely expensive. Therefore, we propose in this paper an innovative ontology development methodology. Our contributions can be summarized as: (i) We have continued the development and critical improvement of OMIT, solidly based on our previous research outcomes. (ii) We have explored effective and efficient algorithms with which the ontology development can be seamlessly combined with machine intelligence and be accomplished in a semi-automated manner, thus significantly reducing large amounts of human efforts. A set of experiments have been conducted to thoroughly evaluate our proposed methodology. PMID:25025130

  17. The effects of compressive preloads on the compression-after-impact strength of carbon/epoxy

    NASA Technical Reports Server (NTRS)

    Nettles, A. T.; Lance, D. G.

    1992-01-01

    A preloading device was used to examine the effects of compressive prestress on the compression-after-impact (CAI) strength of 16-ply, quasi-isotropic carbon epoxy test coupons. T300/934 material was evaluated at preloads from 200 to 4000 lb at impact energies from 1 to 9 joules. IM7/8551-7 material was evaluated at preloads from 4000 to 10,000 lb at impact energies from 4 to 16 joules. Advanced design of experiments methodology was used to design and evaluate the test matrices. The results showed that no statistically significant change in CAI strength could be contributed to the amount of compressive preload applied to the specimen.

  18. Inhibitory effects of rosmarinic acid extracts on porcine pancreatic amylase in vitro.

    PubMed

    McCue, Patrick P; Shetty, Kalidas

    2004-01-01

    Porcine pancreatic alpha-amylase (PPA) was allowed to react with herbal extracts containing rosmarinic acid (RA) and purified RA. The derivatized enzyme-phytochemical mixtures obtained were characterized for residual amylase activity. These in vitro experiments showed that the amylase activity was inhibited in the presence of these phytochemicals. The extent of amylase inhibition correlated with increased concentration of RA. RA-containing oregano extracts yielded higher than expected amylase inhibition than similar amount of purified RA, suggesting that other phenolic compounds or phenolic synergies may contribute to additional amylase inhibitory activity. The significance of food-grade, plant-based amylase inhibitors for modulation of diabetes mellitus and other oxidation-linked diseases is hypothesized and discussed.

  19. Frequency response of electrochemical cells

    NASA Technical Reports Server (NTRS)

    Thomas, Daniel L.

    1990-01-01

    The main objective was to examine the feasibility of using frequency response techniques (1) as a tool in destructive physical analysis of batteries, particularly for estimating electrode structural parameters such as specific area, porosity, and tortuosity and (2) as a non-destructive testing technique for obtaining information such as state of charge and acceptability for space flight. The phenomena that contribute to the frequency response of an electrode include: (1) double layer capacitance; (2) Faradaic reaction resistance; (3) mass transfer of Warburg impedance; and (4) ohmic solution resistance. Nickel cadmium cells were investigated in solutions of KOH. A significant amount of data was acquired. Quantitative data analysis, using the developed software, is planned for the future.

  20. Graphene oxide papers modified by divalent ions-enhancing mechanical properties via chemical cross-linking.

    PubMed

    Park, Sungjin; Lee, Kyoung-Seok; Bozoklu, Gulay; Cai, Weiwei; Nguyen, Sonbinh T; Ruoff, Rodney S

    2008-03-01

    Significant enhancement in mechanical stiffness (10-200%) and fracture strength (approximately 50%) of graphene oxide paper, a novel paperlike material made from individual graphene oxide sheets, can be achieved upon modification with a small amount (less than 1 wt %) of Mg(2+) and Ca(2+). These results can be readily rationalized in terms of the chemical interactions between the functional groups of the graphene oxide sheets and the divalent metals ions. While oxygen functional groups on the basal planes of the sheets and the carboxylate groups on the edges can both bond to Mg(2+) and Ca(2+), the main contribution to mechanical enhancement of the paper comes from the latter.

  1. Predicting organizational citizenship behavior from the functional analysis and role identity perspectives: further evidence in Spanish employees.

    PubMed

    Dávila, Ma Celeste; Finkelstein, Marcia A

    2010-05-01

    Organizational citizenship behavior (OCB) is a prosocial activity with similarities to volunteerism. The purpose of this work is to contribute new evidence about the relevance to OCB of two models of sustained volunteerism, functional analysis and role identity theory. A total of 983 Spanish employees at49 organizations completed surveys measuring amount of OCB, motives for engaging in citizenship behavior, and the degree to which respondents developed an organizational citizen role identity. The results showed that both motives and role identity were significant predictors of OCB, with motive partially mediating the role identity-OCB relationship. The findings suggest that similar mechanisms are involved in sustaining volunteerism and OCB.

  2. Semiconductor superlattice photodetectors

    NASA Technical Reports Server (NTRS)

    Chuang, S. L.; Hess, K.; Coleman, J. J.; Leburton, J. P.

    1986-01-01

    Technical progress made in the study of superlattice photoconductors is summarized and papers submitted for publication are listed. Since the quantum-well regions may contain several subbands, each of which may be occupied by electrons depending on the doping concentrations, it is important to include the multi-subbands in calculating the impact ionization rate. The electrons occupying the higher subbands require a smaller amount of energy to get out of the quantum well; thus, those higher level subband electrons contribute significantly to the impact ionization rate. The results of the subbands have been calculated. Results concerning the nonparabolicity effect of the band structure, the effect of the quantum-well size, and the effect of the band-edge discontinuity and doping are also summarized.

  3. Gulf of Mexico Integrated Science - Tampa Bay Study: Watershed and Estuary Mapping

    USGS Publications Warehouse

    Hansen, Mark

    2005-01-01

    Tampa Bay, Florida, and its environs have experienced phenomenal urban growth and significant changes in land-use practices over the past 50 years. This trend is expected to continue, with human activity intensifying and affecting a wider geographic region. Urbanization creates impervious surfaces, which increase stormwater runoff and contribute to greater amounts of chemicals flowing into coastal waters. Man-made structures including bridges, a gas pipeline, desalination plant, ports, navigation channels, and extensive sea walls have been built and will continue to be maintained and modified. This task of the Tampa Bay Study aims to provide a better understanding of these and other man-made impacts on the Tampa Bay region.

  4. Lean in service industries: A literature review

    NASA Astrophysics Data System (ADS)

    V, Vignesh; Suresh, M.; Aramvalarthan, S.

    2016-09-01

    Lean service is an amalgamation of tools and practices which, if applied appropriately, would definitely improve the existing quality of operations and ensure the generation of a large amount of favourable financial and economic outcomes and improve the behaviour of the workforce. As a result, it assumes of great significance in the fiercely competitive modern world. This article presents a comprehensive bibliographic study about the various lean service practices through a variety of approaches like service improvement, manufacturing, supply chain, market and retailing approaches, etc. Thus it gives a clear view on how the lean services are implemented in various sectors and the contribution of lean service towards improving the quality in the services provided while reducing the costs.

  5. Oxidative Recession, Sulfur Release, and Al203 Spallation for Y-Doped Alloys

    NASA Technical Reports Server (NTRS)

    Smialek, James L.

    2001-01-01

    Second-order spallation phenomena have been noted for Y-doped Rene'N5 after long term oxidation at 1150 degrees C. The reason for this behavior has not been conclusively identified. A mass equivalence analysis has shown that the surface recession resulting from oxidation has the potential of releasing about 0.15 monolayer of sulfur for every 1 mg/sq cm of oxygen reacted for an alloy containing 5 ppmw of sulfur. This amount is significant in comparison to levels that have been shown to result in first-order spallation behavior for undoped alloys. Oxidative recession is therefore speculated to be a contributing source of sulfur and second-order spallation for Y-doped alloys.

  6. Spume Drops: Their Potential Role in Air-Sea Gas Exchange

    NASA Astrophysics Data System (ADS)

    Monahan, Edward C.; Staniec, Allison; Vlahos, Penny

    2017-12-01

    After summarizing the time scales defining the change of the physical properties of spume and other droplets cast up from the sea surface, the time scales governing drop-atmosphere gas exchange are compared. Following a broad review of the spume drop production functions described in the literature, a subset of these functions is selected via objective criteria, to represent typical, upper bound, and lower bound production functions. Three complementary mechanisms driving spume-atmosphere gas exchange are described, and one is then used to estimate the relative importance, over a broad range of wind speeds, of this spume drop mechanism compared to the conventional, diffusional, sea surface mechanism in air-sea gas exchange. While remaining uncertainties in the wind dependence of the spume drop production flux, and in the immediate sea surface gas flux, preclude a definitive conclusion, the findings of this study strongly suggest that, at high wind speeds (>20 m s-1 for dimethyl sulfide and >30 m s-1 for gases such a carbon dioxide), spume drops do make a significant contribution to air-sea gas exchange.Plain Language SummaryThis paper evaluates the existing spume drop generation functions available to date and selects a reasonable upper, lower and mid range function that are reasonable for use in air sea exchange models. Based on these the contribution of spume drops to overall air sea gas exchange at different wind speeds is then evaluated to determine the % contribution of spume. Generally below 20ms-1 spume drops contribute <1% of gas exchange but may account for a significant amount of gas exchange at higher wind speeds.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28525355','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28525355"><span>Does body fat percentage predict post-exercise heart rate response in non-obese children and adolescents?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jezdimirovic, Tatjana; Stajer, Valdemar; Semeredi, Sasa; Calleja-Gonzalez, Julio; Ostojic, Sergej M</p> <p>2017-05-24</p> <p>A correlation between adiposity and post-exercise autonomic regulation has been established in overweight and obese children. However, little information exists about this link in non-obese youth. The main purpose of this cross-sectional study was to describe the relationship between body fat percentage (BFP) and heart rate recovery after exercise [post-exercise heart rate (PEHR)], a marker of autonomic regulation, in normal-weight children and adolescents. We evaluated the body composition of 183 children and adolescents (age 15.0±2.3 years; 132 boys and 51 girls) who performed a maximal graded exercise test on a treadmill, with the heart rate monitored during and immediately after exercise. A strong positive trend was observed in the association between BFP and PEHR (r=0.14; p=0.06). Hierarchical multiple regression revealed that our model explained 18.3% of the variance in PEHR (p=0.00), yet BFP accounted for only 0.9% of the variability in PEHR (p=0.16). The evaluation of the contribution of each independent variable revealed that only two variables made a unique statistically significant contribution to our model (p<0.01), with age contributing 38.7% to our model (p=0.00) while gender accounted for an additional 25.5% (p=0.01). Neither BFP (14.4%; p=0.16) nor cardiorespiratory endurance (5.0%, p=0.60) made a significant unique contribution to the model. Body fatness seems to poorly predict PEHR in our sample of non-obese children and adolescents, while non-modifiable variables (age and gender) were demonstrated as strong predictors of heart rate recovery. The low amount of body fat reported in non-obese young participants was perhaps too small to cause disturbances in autonomic nervous system regulation.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2001OcMod...3...51G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2001OcMod...3...51G"><span>The sources of Antarctic bottom water in a global ice ocean model</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Goosse, Hugues; Campin, Jean-Michel; Tartinville, Benoı̂t</p> <p></p> <p>Two mechanisms contribute to the formation of Antarctic bottom water (AABW). The first, and probably the most important, is initiated by the brine released on the Antarctic continental shelf during ice formation which is responsible for an increase in salinity. After mixing with ambient water at the shelf break, this salty and dense water sinks along the shelf slope and invades the deepest part of the global ocean. For the second one, the increase of surface water density is due to strong cooling at the ocean-atmosphere interface, together with a contribution from brine release. This induces deep convection and the renewal of deep waters. The relative importance of these two mechanisms is investigated in a global coupled ice-ocean model. Chlorofluorocarbon (CFC) concentrations simulated by the model compare favourably with observations, suggesting a reasonable deep water ventilation in the Southern Ocean, except close to Antarctica where concentrations are too high. Two artificial passive tracers released at surface on the Antarctic continental shelf and in the open-ocean allow to show clearly that the two mechanisms contribute significantly to the renewal of AABW in the model. This indicates that open-ocean convection is overestimated in our simulation. Additional experiments show that the amount of AABW production due to the export of dense shelf waters is quite sensitive to the parameterisation of the effect of downsloping and meso-scale eddies. Nevertheless, shelf waters always contribute significantly to deep water renewal. Besides, increasing the P.R. Gent, J.C. McWilliams [Journal of Physical Oceanography 20 (1990) 150-155] thickness diffusion can nearly suppress the AABW formation by open-ocean convection.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16705465','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16705465"><span>The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Brown, C M; Rea, T J; Hamon, S C; Hixson, J E; Boerwinkle, E; Clark, A G; Sing, C F</p> <p>2006-07-01</p> <p>Apolipoproteins (apo) A-I and C-III are components of high-density lipoprotein-cholesterol (HDL-C), a quantitative trait negatively correlated with risk of cardiovascular disease (CVD). We analyzed the contribution of individual and pairwise combinations of single nucleotide polymorphisms (SNPs) in the APOA1/APOC3 genes to HDL-C variability to evaluate (1) consistency of published single-SNP studies with our single-SNP analyses; (2) consistency of single-SNP and two-SNP phenotype-genotype relationships across race-, gender-, and geographical location-dependent contexts; and (3) the contribution of single SNPs and pairs of SNPs to variability beyond that explained by plasma apo A-I concentration. We analyzed 45 SNPs in 3,831 young African-American (N=1,858) and European-American (N=1,973) females and males ascertained by the Coronary Artery Risk Development in Young Adults (CARDIA) study. We found three SNPs that significantly impact HDL-C variability in both the literature and the CARDIA sample. Single-SNP analyses identified only one of five significant HDL-C SNP genotype relationships in the CARDIA study that was consistent across all race-, gender-, and geographical location-dependent contexts. The other four were consistent across geographical locations for a particular race-gender context. The portion of total phenotypic variance explained by single-SNP genotypes and genotypes defined by pairs of SNPs was less than 3%, an amount that is miniscule compared to the contribution explained by variability in plasma apo A-I concentration. Our findings illustrate the impact of context-dependence on SNP selection for prediction of CVD risk factor variability.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28463031','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28463031"><span>Amount and quality of sleep: exploring the role of stress and work experience in a sample of obstetrician-gynecologists.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Taouk, Laura; Farrow, Victoria A; Schulkin, Jay</p> <p>2017-05-02</p> <p>Sufficient sleep is necessary for optimal performance and the delivery of safe and effective health care. To establish an empirical understanding of physician fatigue, the present study investigated the factors that contributed to the amount and the quality of sleep among obstetricians and gynecologists (ob-gyns). A survey of personal and work experiences was sent to 495 eligible physicians belonging to the American College of Obstetricians and Gynecologists (ACOG). Data were obtained from 287 ob-gyns for a response rate of 58.0%. Associations between sleep-related items and measures of stress and work-related factors were explored. Ob-gyns in our sample reported sleeping an average of 6.5 hours a night with 29.2% indicating that they received very or fairly bad quality of sleep. Average amount and quality of sleep were found to be independently related to the hours worked weekly, colleague support for a work-home balance, practice setting, perceived work-control, physician-specific stressors and perceived stress. In summary models, hours worked and perceived stress scores consistently emerged as predictors of amount of sleep. Overall, findings explained a small portion of the variance in sleep. Considering the multitude of factors that contribute to sleep, subtle associations warrant further investigation.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27389997','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27389997"><span>Influence of fossil-fuel power plant emissions on the surface fine particulate matter in the Seoul Capital Area, South Korea.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kim, Byeong-Uk; Kim, Okgil; Kim, Hyun Cheol; Kim, Soontae</p> <p>2016-09-01</p> <p>The South Korean government plans to reduce region-wide annual PM2.5 (particulate matter with an aerodynamic diameter ≤2.5 μm) concentrations in the Seoul Capital Area (SCA) from 2010 levels of 27 µg/m(3) to 20 µg/m(3) by 2024. At the same time, it is inevitable that emissions from fossil-fuel power plants will continue to increase if electricity generation expands and the generation portfolio remains the same in the future. To estimate incremental PM2.5 contributions due to projected electricity generation growth in South Korea, we utilized an ensemble forecasting member of the Integrated Multidimensional Air Quality System for Korea based on the Community Multi-scale Air Quality model. We performed sensitivity runs with across-the-board emission reductions for all fossil-fuel power plants in South Korea to estimate the contribution of PM2.5 from domestic fossil-fuel power plants. We estimated that fossil-fuel power plants are responsible for 2.4% of the annual PM2.5 national ambient air quality standard in the SCA as of 2010. Based on the electricity generation and the annual contribution of fossil-fuel power plants in 2010, we estimated that annual PM2.5 concentrations may increase by 0.2 µg/m(3) per 100 TWhr due to additional electricity generation. With currently available information on future electricity demands, we estimated that the total future contribution of fossil-fuel power plants would be 0.87 µg/m(3), which is 12.4% of the target reduction amount of the annual PM2.5 concentration by 2024. We also approximated that the number of premature deaths caused by existing fossil-fuel power plants would be 736 in 2024. Since the proximity of power plants to the SCA and the types of fuel used significantly impact this estimation, further studies are warranted on the impact of physical parameters of plants, such as location and stack height, on PM2.5 concentrations in the SCA due to each precursor. Improving air quality by reducing fine particle pollution is challenging when fossil-fuel-based electricity production is increasing. We show that an air quality forecasting system based on a photochemical model can be utilized to efficiently estimate PM2.5 contributions from and health impacts of domestic power plants. We derived PM2.5 concentrations per unit amount of electricity production from existing fossil-fuel power plants in South Korea. We assessed the health impacts of existing fossil-fuel power plants and the PM2.5 concentrations per unit electricity production to quantify the significance of existing and future fossil-fuel power plants with respect to the planned PM2.5 reduction target.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22544987','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22544987"><span>Why Do People Use Facebook?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nadkarni, Ashwini; Hofmann, Stefan G</p> <p>2012-02-01</p> <p>The social networking site, Facebook, has gained an enormous amount of popularity. In this article, we review the literature on the factors contributing to Facebook use. We propose a model suggesting that Facebook use is motivated by two primary needs: (1) The need to belong and (2) the need for self-presentation. Demographic and cultural factors contribute to the need to belong, whereas neuroticism, narcissism, shyness, self-esteem and self-worth contribute to the need for self presentation. Areas for future research are discussed.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3335399','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3335399"><span>Why Do People Use Facebook?</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Nadkarni, Ashwini; Hofmann, Stefan G.</p> <p>2011-01-01</p> <p>The social networking site, Facebook, has gained an enormous amount of popularity. In this article, we review the literature on the factors contributing to Facebook use. We propose a model suggesting that Facebook use is motivated by two primary needs: (1) The need to belong and (2) the need for self-presentation. Demographic and cultural factors contribute to the need to belong, whereas neuroticism, narcissism, shyness, self-esteem and self-worth contribute to the need for self presentation. Areas for future research are discussed. PMID:22544987</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018AtmEn.182..225T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018AtmEn.182..225T"><span>Temporal and spatial characteristics of dust devils and their contribution to the aerosol budget in East Asia-An analysis using a new parameterization scheme for dust devils</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Tang, Yaoguo; Han, Yongxiang; Liu, Zhaohuan</p> <p>2018-06-01</p> <p>Dust aerosols are the main aerosol components of the atmosphere that affect climate change, but the contribution of dust devils to the atmospheric dust aerosol budget is uncertain. In this study, a new parameterization scheme for dust devils was established and coupled with WRF-Chem, and the diurnal and monthly variations and the contribution of dust devils to the atmospheric dust aerosol budget in East Asia was simulated. The results show that 1) both the diurnal and monthly variations in dust devil emissions in East Asia had unimodal distributions, with peaks in the afternoon and the summer that were similar to the observations; 2) the simulated dust devils occurred frequently in deserts, including the Gobi. The distributed area and the intensity center of the dust devil moved from east to west during the day; 3) the ratio between the availability of convective buoyancy relative to the frictional dissipation was the main factor that limited the presence of dust devils. The position of the dust devil formation, the surface temperature, and the boundary layer height determined the dust devil intensity; 4) the contribution of dust devils to atmospheric dust aerosols determined in East Asia was 30.4 ± 13%, thereby suggesting that dust devils contribute significantly to the total amount of atmospheric dust aerosols. Although the new parameterization scheme for dust devils was rough, it was helpful for understanding the distribution of dust devils and their contribution to the dust aerosol budget.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12214653','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12214653"><span>Contribution of biogenic emissions to the formation of ozone and particulate matter in the eastern United States.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pun, Betty K; Wu, Shiang-Yuh; Seigneur, Christian</p> <p>2002-08-15</p> <p>As anthropogenic emissions of ozone (O3) precursors, fine particulate matter (PM2.5), and PM2.5 precursors continue to decrease in the United States, the fraction of O3 and PM2.5 attributable to natural sources may become significant in some locations, reducing the efficacy that can be expected from future controls of anthropogenic sources. Modeling studies were conducted to estimate the contribution of biogenic emissions to the formation of O3 and PM2.5 in Nashville/TN and the northeastern United States. Two approaches were used to bound the estimates. In an anthropogenic simulation, biogenic emissions and their influence at the domain boundaries were eliminated. Contributions of biogenic compounds to the simulated concentrations of O3 and PM2.5 were determined by the deviation of the concentrations in the anthropogenic case from those in the base case. A biogenic simulation was used to assess the amounts of O3 and PM2.5 produced in an environment free from anthropogenic influences in emissions and boundary conditions. In both locations, the contribution of biogenic emissions to O3 was small (<23%) on a domain-wide basis, despite significant biogenic volatile organic compounds (VOC) emissions (65-89% of total VOC emissions). However, the production of O3 was much more sensitive to biogenic emissions in urban areas (22-34%). Therefore, the effects of biogenic emissions on O3 manifested mostly via their interaction with anthropogenic emissions of NOx. In the anthropogenic simulations, the average contribution of biogenic and natural sources to PM2.5 was estimated at 9% in Nashville/TN and 12% in the northeast domain. Because of the long atmospheric lifetimes of PM2.5, the contribution of biogenic/natural PM2.5 from the boundary conditions was higher than the contribution of biogenic aerosols produced within the domain. The elimination of biogenic emissions also affected the chemistry of other secondary PM2.5 components. Very little PM2.5 was formed in the biogenic simulations.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24296778','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24296778"><span>Field-testing a new directional passive air sampler for fugitive dust in a complex industrial source environment.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ferranti, E J S; Fryer, M; Sweetman, A J; Garcia, M A Solera; Timmis, R J</p> <p>2014-01-01</p> <p>Quantifying the sources of fugitive dusts on complex industrial sites is essential for regulation and effective dust management. This study applied two recently-patented Directional Passive Air Samplers (DPAS) to measure the fugitive dust contribution from a Metal Recovery Plant (MRP) located on the periphery of a major steelworks site. The DPAS can collect separate samples for winds from different directions (12 × 30° sectors), and the collected dust may be quantified using several different measurement methods. The DPASs were located up and down-prevailing-wind of the MRP processing area to (i) identify and measure the contribution made by the MRP processing operation; (ii) monitor this contribution during the processing of a particularly dusty material; and (iii) detect any changes to this contribution following new dust-control measures. Sampling took place over a 12-month period and the amount of dust was quantified using photographic, magnetic and mass-loading measurement methods. The DPASs are able to effectively resolve the incoming dust signal from the wider steelworks complex, and also different sources of fugitive dust from the MRP processing area. There was no confirmable increase in the dust contribution from the MRP during the processing of a particularly dusty material, but dust levels significantly reduced following the introduction of new dust-control measures. This research was undertaken in a regulatory context, and the results provide a unique evidence-base for current and future operational or regulatory decisions.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19990109670','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19990109670"><span>Contribution of Tropical Cyclones to the North Pacific Climatological Rainfall as Observed from Satellites</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Rodgers, Edward B.; Adler, Robert F.; Pierce, Harold F.</p> <p>1997-01-01</p> <p>Tropical cyclone monthly rainfall amounts are estimated from passive microwave satellite observations for an eleven year period. These satellite-derived rainfall amounts are used to assess the impact of tropical cyclone rainfall in altering the geographical, seasonal, and inter-annual distribution of the North Pacific Ocean total rainfall during June-November when tropical cyclones are most important. To estimate these tropical cyclone rainfall amounts, mean monthly rain rates are derived from passive microwave satellite observations within 444 km radius of the center of those North Pacific tropical cyclones that reached storm stage and greater. These rain rate observations are converted to monthly rainfall amounts and then compared to those for non-tropical cyclone systems. The main results of this study indicate that: 1) tropical cyclones contribute 7% of the rainfall to the entire domain of the North Pacific during the tropical cyclone season and 12%, 3%, and 4% when the study area is limited to, respectively, the western, central, and eastern third of the ocean; 2) the maxima in tropical cyclone rainfall are poleward (5 deg to 10 deg latitude depending on longitude) of the maxima in non-tropical cyclone rainfall; 3) tropical cyclones contribute a maximum of 30% northeast of the Philippine Islands and 40% of the lower Baja California coast; 4) in the western North Pacific, the tropical cyclone rainfall lags the total rainfall by approximately two months and shows seasonal latitudinal variation following the ITCZ; and 5) in general, tropical cyclone rainfall is enhanced during the El Nino years by warm SSTs in the eastern North Pacific and by the monsoon trough in the western and central North Pacific.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2000JApMe..39.1658R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2000JApMe..39.1658R"><span>Contribution of Tropical Cyclones to the North Pacific Climatological Rainfall as Observed from Satellites.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Rodgers, Edward B.; Adler, Robert F.; Pierce, Harold F.</p> <p>2000-10-01</p> <p>Tropical cyclone monthly rainfall amounts are estimated from passive microwave satellite observations for an 11-yr period. These satellite-derived rainfall amounts are used to assess the impact of tropical cyclone rainfall in altering the geographical, seasonal, and interannual distribution of the North Pacific Ocean total rainfall during June-November when tropical cyclones are most important.To estimate these tropical cyclone rainfall amounts, mean monthly rain rates are derived from passive microwave satellite observations within 444-km radius of the center of those North Pacific tropical cyclones that reached storm stage and greater. These rain-rate observations are converted to monthly rainfall amounts and then compared with those for nontropical cyclone systems.The main results of this study indicate that 1) tropical cyclones contribute 7% of the rainfall to the entire domain of the North Pacific during the tropical cyclone season and 12%, 3%, and 4% when the study area is limited to, respectively, the western, central, and eastern third of the ocean; 2) the maximum tropical cyclone rainfall is poleward (5°-10° latitude depending on longitude) of the maximum nontropical cyclone rainfall; 3) tropical cyclones contribute a maximum of 30% northeast of the Philippine Islands and 40% off the lower Baja California coast; 4) in the western North Pacific, the tropical cyclone rainfall lags the total rainfall by approximately two months and shows seasonal latitudinal variation following the Intertropical Convergence Zone; and 5) in general, tropical cyclone rainfall is enhanced during the El Niño years by warm SSTs in the eastern North Pacific and by the monsoon trough in the western and central North Pacific.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19151592','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19151592"><span>Effect of high-intensity interval exercise on lipid oxidation during postexercise recovery.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Malatesta, Davide; Werlen, Catherine; Bulfaro, Stefano; Chenevière, Xavier; Borrani, Fabio</p> <p>2009-02-01</p> <p>The aim of this study was to examine whether lipid oxidation predominates during 3 h of postexercise recovery in high-intensity interval exercise as compared with moderate-intensity continuous exercise on a cycle ergometer in fit young men (n = 12; 24.6 +/- 0.6 yr). The energy substrate partitioning was evaluated during and after high-intensity submaximal interval exercise (INT, 1-min intervals at 80% of maximal aerobic power output [Wmax] with an intervening 1 min of active recovery at 40% Wmax) and 60-min moderate-intensity continuous exercise at 45% of maximal oxygen uptake (C45%) as well as a time-matched resting control trial (CON). Exercise bouts were matched for mechanical work output. During exercise, a significantly greater contribution of CHO and a lower contribution of lipid to energy expenditure were found in INT (512.7 +/- 26.6 and 41.0 +/- 14.0 kcal, respectively) than in C45% (406.3 +/- 21.2 and 170.3 +/- 24.0 kcal, respectively; P < 0.001) despite similar overall energy expenditure in both exercise trials (P = 0.13). During recovery, there were no significant differences between INT and C45% in substrate turnover and oxidation (P > 0.05). On the other hand, the mean contribution of lipids to energy yield was significantly higher after exercise trials (C45% = 61.3 +/- 4.2 kcal; INT = 66.7 +/- 4.7 kcal) than after CON (51.5 +/- 3.4 kcal; P < 0.05). These findings show that lipid oxidation during postexercise recovery was increased by a similar amount on two isoenergetic exercise bouts of different forms and intensities compared with the time-matched no-exercise control trial.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15252353','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15252353"><span>Corneal and lenticular components of total astigmatism in a preschool sample.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Shankar, Sunita; Bobier, William R</p> <p>2004-07-01</p> <p>To examine the contribution of corneal and lenticular components to total astigmatism in preschool low and high astigmats to determine whether there was any compensation for high astigmatism by the lenticular component. Cycloplegic refractive and keratometric measures using the Retinomax K-Plus (Nikon Inc., Melville, NY) were conducted on 129 children (mean age, 51.1 +/- 8.4 mo) in Oxford County, Canada. We divided the sample into high astigmats (total cylinder > or =1 D; mean, 1.38 +/- 0.43 D; n = 29) and normal astigmats (total cylinder < or =0.75 D; mean, 0.22 +/- 0.20 D; n = 100). Measures of total and corneal cylinder were transposed into J0 and J45 components, where positive and negative J0 values quantified with-the-rule (WTR) and against-the-rule astigmatisms, respectively, and J45 quantified oblique astigmatism. WTR astigmatism was dominant in both the high and normal astigmatic group. J0 and J45 components of corneal astigmatism were highly correlated with total astigmatism in high astigmats, whereas only J0 was significantly correlated with total astigmatism in normal astigmats. Although the magnitude of total and corneal cylinder was significantly greater in high astigmats, overall lenticular cylinder was similar in both groups. However, the Fourier transforms showed high astigmats to have significantly lower lenticular J0 and higher lenticular J45 than the normal astigmats. Astigmatism in 3- to 5-year-old children is primarily corneal. In preschool children, the lens does not vary in response to high amounts of corneal WTR astigmatism, and in fact, it increases the oblique astigmatism component when the corneal component is high. In high astigmats, lenticular astigmatism contributes to both J0 and J45 components, whereas the corneal contribution is primarily J0.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_22 --> <div id="page_23" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="441"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016PSST...25f5004G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016PSST...25f5004G"><span>An ionization region model of the reactive Ar/O2 high power impulse magnetron sputtering discharge</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gudmundsson, J. T.; Lundin, D.; Brenning, N.; Raadu, M. A.; Huo, Chunqing; Minea, T. M.</p> <p>2016-12-01</p> <p>A new reactive ionization region model (R-IRM) is developed to describe the reactive Ar/O2 high power impulse magnetron sputtering (HiPIMS) discharge with a titanium target. It is then applied to study the temporal behavior of the discharge plasma parameters such as electron density, the neutral and ion composition, the ionization fraction of the sputtered vapor, the oxygen dissociation fraction, and the composition of the discharge current. We study and compare the discharge properties when the discharge is operated in the two well established operating modes, the metal mode and the poisoned mode. Experimentally, it is found that in the metal mode the discharge current waveform displays a typical non-reactive evolution, while in the poisoned mode the discharge current waveform becomes distinctly triangular and the current increases significantly. Using the R-IRM we explore the current increase and find that when the discharge is operated in the metal mode Ar+ and Ti+ -ions contribute most significantly (roughly equal amounts) to the discharge current while in the poisoned mode the Ar+ -ions contribute most significantly to the discharge current and the contribution of O+ -ions, Ti+ -ions, and secondary electron emission is much smaller. Furthermore, we find that recycling of atoms coming from the target, that are subsequently ionized, is required for the current generation in both modes of operation. From the R-IRM results it is found that in the metal mode self-sputter recycling dominates and in the poisoned mode working gas recycling dominates. We also show that working gas recycling can lead to very high discharge currents but never to a runaway. It is concluded that the dominating type of recycling determines the discharge current waveform.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24809493','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24809493"><span>Cyprodinil retention on mixtures of soil and solid wastes from wineries. Effects of waste dose and ageing.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rodríguez-Salgado, Isabel; Paradelo-Pérez, Marcos; Pérez-Rodríguez, Paula; Cutillas-Barreiro, Laura; Fernández-Calviño, David; Nóvoa-Muñoz, Juan Carlos; Arias-Estévez, Manuel</p> <p>2014-01-01</p> <p>In spite of its wide-world economic relevance, wine production generates a huge amount of waste that threatens the environment. A batch experiment was designed to assess the effect of the amendment of an agricultural soil with two winery wastes (perlite and bentonite wastes) in the immobilization of cyprodinil. Waste addition (0, 10, 20, 40, and 80 Mg ha(-1)) and different times of incubation of soil-waste mixtures (1, 30, and 120 days) were tested. The addition of wastes improved the soil's ability to immobilize cyprodinil, which was significantly correlated to total C content in soil-waste mixtures. Longer incubation times decreased the cyprodinil sorption possibly due to the mineralization of organic matter but also as a consequence of the high pH values reached after bentonite waste addition (up to 10.0). Cyprodinil desorption increased as the amount of waste added to soil, and the incubation time increased. The use of these winery wastes contributes to a more sustainable agriculture preventing fungicide mobilization to groundwater.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70012142','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70012142"><span>Electrical properties of granite with implications for the lower crust.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Olhoeft, G.R.</p> <p>1981-01-01</p> <p>The electrical properties of granite appear to be dominantly controlled by the amount of free water in the granite and by temperature. Minor contributions to the electrical properties are provided by hydrostatic and lithostatic pressure, structurally bound water, oxygen fugacity, and other parameters. The effect of sulphur fugacity may be important but is experimentally unconfirmed. In addition to changing the magnitude of electrical properties, the amount and chemistry of water in granite significantly changes the temperature dependence of the electrical properties. With increasing temperature, changes in water content retain large, but lessened, effects on electrical properties. Near room temperature, a monolayer of water will decrease the electrical resistivity by an order of magnitude. Several weight-percent water may decrease the electrical resistivity by as much as nine orders of magnitude and decrease the thermal activation energy by a factor of five. At elevated temperatures just below granitic melting, a few weight-percent water may still decrease the resistivity by as much as 3 orders of magnitude and the activation energy by a factor of two.-Author</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29596740','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29596740"><span>Formation of Particulate Matter from the Oxidation of Evaporated Hydraulic Fracturing Wastewater.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bean, Jeffrey K; Bhandari, Sahil; Bilotto, Anthony; Hildebrandt Ruiz, L</p> <p>2018-04-17</p> <p>The use of hydraulic fracturing for production of petroleum and natural gas has increased dramatically in the past decade, but the environmental impacts of this technology remain unclear. Experiments were conducted to quantify airborne emissions from 12 samples of hydraulic fracturing flowback wastewater collected in the Permian Basin, as well as the photochemical processing of these emissions leading to the formation of particulate matter (PM). The concentration of total volatile carbon (hydrocarbons evaporating at room temperature) averaged 29 mg of carbon per liter. After photochemical oxidation under high NO x conditions, the amount of organic PM formed per milliliter of wastewater evaporated averaged 24 μg; the amount of ammonium nitrate formed averaged 262 μg. Based on the mean PM formation observed in these experiments, the estimated formation of PM from evaporated flowback wastewater in the state of Texas is in the range of estimated PM emissions from diesel engines used in oil rigs. Evaporation of flowback wastewater, a hitherto unrecognized source of secondary pollutants, could significantly contribute to ambient PM concentrations.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26575717','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26575717"><span>Effect of water and gluten on physico-chemical properties and stability of ready to eat shelf-stable pasta.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Diantom, Agoura; Carini, Eleonora; Curti, Elena; Cassotta, Fabrizio; D'Alessandro, Alessandro; Vittadini, Elena</p> <p>2016-03-15</p> <p>A multi-analytical and multi-dimensional approach was used to investigate the effect of moisture and gluten on physico-chemical properties of shelf-stable ready to eat (RTE) pasta. Moisture and frozen water contents were not affected by formulation nor storage time. Hardness and retrograded amylopectin significantly increased during storage in all samples, more markedly in pasta with the lowest moisture content. Higher amounts of water and gluten reduced pasta hardening and contributed to control RTE pasta quality. (1)H FID became steeper in all samples during storage, but no effect of high moisture and gluten levels was observed on the mobility of these protons. Three proton T2 populations were observed (population C, population D and population E). Population C and D were not resolved during all storage. (1)H T2 relaxation time of the most abundant population (population E) shifted to shorter times and the amount of protons increased during storage, more importantly in the samples with lower moisture and gluten content. Copyright © 2015 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/6681334','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/6681334"><span>Estimates of amounts of soil removal for clean-up of transuranics at NAEG offsite safety-shot sites</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Kinnison, R.R.; Gilbert, R.O.</p> <p></p> <p>Rough estimates are given for the amount of soil removal necessary to decontaminate five representative safety-shot areas. In order to decontaminate to levels of less than 160 pCi /sup 239/Pu per gram of surface soil, it is estimated that over one-half million tons of soil would have to be removed from the five areas. This is a preliminary estimate based on summary data and concentration contour maps readily available in NAEG publications. More accurate estimates could be obtained by applying Kriging techniques to available soil data if the need arises. The inclusion of /sup 241/Am and /sup 238/Pu activities domore » not significantly increase the soil tonnage estimates obtained for /sup 239/ /sup 240/Pu because of their relatively small contributions to total transuranic activity. The magnitude of the errors inherent in our use of summary data to obtain rough estimates also suggests that a revision of the tonnage estimates for /sup 239/ /sup 240/Pu to include /sup 241/Am and /sup 238/Pu is not warranted.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/22661098-deep-broadband-spectral-line-surveys-molecule-rich-interstellar-clouds','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22661098-deep-broadband-spectral-line-surveys-molecule-rich-interstellar-clouds"><span>Deep, Broadband Spectral Line Surveys of Molecule-rich Interstellar Clouds</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Widicus Weaver, Susanna L.; Laas, Jacob C.; Zou, Luyao</p> <p>2017-09-01</p> <p>Spectral line surveys are an indispensable tool for exploring the physical and chemical evolution of astrophysical environments due to the vast amount of data that can be obtained in a relatively short amount of time. We present deep, broadband spectral line surveys of 30 interstellar clouds using two broadband λ  = 1.3 mm receivers at the Caltech Submillimeter Observatory. This information can be used to probe the influence of physical environment on molecular complexity. We observed a wide variety of sources to examine the relative abundances of organic molecules as they relate to the physical properties of the source (i.e., temperature,more » density, dynamics, etc.). The spectra are highly sensitive, with noise levels ≤25 mK at a velocity resolution of ∼0.35 km s{sup −1}. In the initial analysis presented here, column densities and rotational temperatures have been determined for the molecular species that contribute significantly to the spectral line density in this wavelength regime. We present these results and discuss their implications for complex molecule formation in the interstellar medium.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/20020021239','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20020021239"><span>Water Vapor Tracers as Diagnostics of the Regional Hydrologic Cycle</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Bosilovich, Michael G.; Schubert, Siegfried D.; Einaudi, Franco (Technical Monitor)</p> <p>2001-01-01</p> <p>Numerous studies suggest that local feedback of surface evaporation on precipitation, or recycling, is a significant source of water for precipitation. Quantitative results on the exact amount of recycling have been difficult to obtain in view of the inherent limitations of diagnostic recycling calculations. The current study describes a calculation of the amount of local and remote geographic sources of surface evaporation for precipitation, based on the implementation of three-dimensional constituent tracers of regional water vapor sources (termed water vapor tracers, WVT) in a general circulation model. The major limitation on the accuracy of the recycling estimates is the veracity of the numerically simulated hydrological cycle, though we note that this approach can also be implemented within the context of a data assimilation system. In the WVT approach, each tracer is associated with an evaporative source region for a prognostic three-dimensional variable that represents a partial amount of the total atmospheric water vapor. The physical processes that act on a WVT are determined in proportion to those that act on the model's prognostic water vapor. In this way, the local and remote sources of water for precipitation can be predicted within the model simulation, and can be validated against the model's prognostic water vapor. As a demonstration of the method, the regional hydrologic cycles for North America and India are evaluated for six summers (June, July and August) of model simulation. More than 50% of the precipitation in the Midwestern United States came from continental regional sources, and the local source was the largest of the regional tracers (14%). The Gulf of Mexico and Atlantic regions contributed 18% of the water for Midwestern precipitation, but further analysis suggests that the greater region of the Tropical Atlantic Ocean may also contribute significantly. In most North American continental regions, the local source of precipitation is correlated with total precipitation. There is a general positive correlation between local evaporation and local precipitation, but it can be weaker because large evaporation can occur when precipitation is inhibited. In India, the local source of precipitation is a small percentage of the precipitation owing to the dominance of the atmospheric transport of oceanic water. The southern Indian Ocean provides a key source of water for both the Indian continent and the Sahelian region.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16383816','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16383816"><span>Balance of dark and luminous mass in rotating galaxies.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>McGaugh, Stacy S</p> <p>2005-10-21</p> <p>A fine balance between dark and baryonic mass is observed in spiral galaxies. As the contribution of the baryons to the total rotation velocity increases, the contribution of the dark matter decreases by a compensating amount. This poses a fine-tuning problem for galaxy formation models, and may point to new physics for dark matter particles or even a modification of gravity.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24526614','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24526614"><span>The contribution of evaporative emissions from gasoline vehicles to the volatile organic compound inventory in Mexico City.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Schifter, I; Díaz, L; Rodríguez, R; González-Macías, C</p> <p>2014-06-01</p> <p>The strategy for decreasing volatile organic compound emissions in Mexico has been focused much more on tailpipe emissions than on evaporative emissions, so there is very little information on the contribution of evaporative emissions to the total volatile organic compound inventory. We examined the magnitudes of exhaust and evaporative volatile organic compound emissions, and the species emitted, in a representative fleet of light-duty gasoline vehicles in the Metropolitan Area of Mexico City. The US "FTP-75" test protocol was used to estimate volatile organic compound emissions associated with diurnal evaporative losses, and when the engine is started and a journey begins. The amount and nature of the volatile organic compounds emitted under these conditions have not previously been accounted in the official inventory of the area. Evaporative emissions from light-duty vehicles in the Metropolitan Area of Mexico City were estimated to be 39 % of the total annual amount of hydrocarbons emitted. Vehicles built before 1992 (16 % of the fleet) were found to be responsible for 43 % of the total hydrocarbon emissions from exhausts and 31 % of the evaporative emissions of organic compounds. The relatively high amounts of volatile organic compounds emitted from older vehicles found in this study show that strong emission controls need to be implemented in order to decrease the contribution of evaporative emissions of this fraction of the fleet.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4007620','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4007620"><span>The importance of having a partner: male help releases females from time limitation during incubation in birds</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2014-01-01</p> <p>Introduction Male contribution to parental care varies widely among avian species. Yet the reasons for this variation, as well as its consequences, are still unclear. Because the amount of care provided by one sex is ultimately constrained by the time available for energy acquisition, contribution by the other sex should increase when overall parental workload is high. We tested this prediction by analyzing male contribution to incubation in 528 populations of 320 species of passerines, where females usually devote more time to incubation than males. Our worldwide sample included species with female-only parental care (the male is not present), incubation feeding (the male feeds the incubating female), and shared incubation (both sexes incubate the eggs). Results Overall nest attentiveness was greatest in species with shared incubation followed by species with incubation feeding and lowest in species with female-only care. Nest attentiveness and the degree of male contribution to incubation in species with shared incubation were very strongly correlated, whereas this correlation was absent in females. Interestingly, female contribution decreased towards the equator while male contribution did not change significantly with latitude. Hence, relative male incubation effort increased towards the equator, whereas that of female decreased. In species with incubation feeding, female nest attentiveness increased with the frequency of male feeding. Conclusions These findings support the hypothesis that male help is indispensable for increasing nest attentiveness in birds, either in the form of incubation feeding (supply of energy) or direct incubation of eggs. We conclude that energy acquisition constraints might be a potent force driving sex-specific contribution to parental care. PMID:24607032</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27759981','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27759981"><span>Validity and reliability of beverage intake questionnaire: evaluating hydration status.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Karabudak, Efsun; Koksal, Eda</p> <p>2016-09-20</p> <p>The purpose of this investigation is to test the validity and reliability the assessment methods for the true beverage consumption of adults. This cross-sectional study was carried out 291 healthy volunteers. The beverage intake questionnaire (BIQ) was prepared in combination with a new one which is developed based on basic principles and the existing one developed for the beverages consumed the most with respect to frequency and amount by Turkish populations. During the initial visit the participants completed BIQ1 and then provided a urine sample to determine urinary specific gravity(USG). For validity, participants recorded the type and quantity of foods and beverages consumed on the same day and previous two days. Two weeks later, for reliability, participants completed the same beverage intake questionnaire (BIQ2). Mean daily total fluid intake was estimated at 1,773 ± 49.4mL using the dietary intake record (DIR), 2,120 ± 49.5 mL with BIQ1 and 1,990 ± 46.3 mL for BIQ2. The largest contribution to total fluid intake was plain water. The response on the two assessment tools (DIR and BIQ1) all beverage intakes were significantly correlated (p < 0.01) except for alcoholic beverage intake. One could see a significant correlation between BIQ1 and BIQ2 in relation to total fluid intakes (r = 0.838,p < 0.01). The USG measurement was negatively correlated with three assessment tools (DIR, BIQ1 and BIQ2), the amount of plain water and the amount of total fluid intake. The self-administered instrument described in this study may be useful for researchers interested in assessing habitual beverage consumption patterns or evaluating hydration status for adults.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23996004','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23996004"><span>Substance P reduces TNF-α-induced apoptosis in human tenocytes through NK-1 receptor stimulation.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Backman, Ludvig J; Eriksson, Daniella E; Danielson, Patrik</p> <p>2014-10-01</p> <p>It has been hypothesised that an upregulation of the neuropeptide substance P (SP) and its preferred receptor, the neurokinin-1 receptor (NK-1 R), is a causative factor in inducing tenocyte hypercellularity, a characteristic of tendinosis, through both proliferative and antiapoptotic stimuli. We have demonstrated earlier that SP stimulates proliferation of human tenocytes in culture. The aim of this study was to investigate whether SP can mediate an antiapoptotic effect in tumour necrosis factor-α (TNF-α)-induced apoptosis of human tenocytes in vitro. A majority (approximately 75%) of tenocytes in culture were immunopositive for TNF Receptor-1 and TNF Receptor-2. Exposure of the cells to TNF-α significantly decreased cell viability, as shown with crystal violet staining. TNF-α furthermore significantly increased the amount of caspase-10 and caspase-3 mRNA, as well as both BID and cleaved-poly ADP ribosome polymerase (c-PARP) protein. Incubation of SP together with TNF-α resulted in a decreased amount of BID and c-PARP, and in a reduced lactate dehydrogenase release, as compared to incubation with TNF-α alone. The SP effect was blocked with a NK-1 R inhibitor. This study shows that SP, through stimulation of the NK-1 R, has the ability to reduce TNF-α-induced apoptosis of human tenocytes. Considering that SP has previously been shown to stimulate tenocyte proliferation, the study confirms SP as a potent regulator of cell-turnover in tendon tissue, capable of stimulating hypercellularity through different mechanisms. This gives further support for the theory that the upregulated amount of SP seen in tendinosis could contribute to hypercellularity. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4742330','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4742330"><span>Intra-specific variation in genome size in maize: cytological and phenotypic correlates</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Realini, María Florencia; Poggio, Lidia; Cámara-Hernández, Julián; González, Graciela Esther</p> <p>2016-01-01</p> <p>Genome size variation accompanies the diversification and evolution of many plant species. Relationships between DNA amount and phenotypic and cytological characteristics form the basis of most hypotheses that ascribe a biological role to genome size. The goal of the present research was to investigate the intra-specific variation in the DNA content in maize populations from Northeastern Argentina and further explore the relationship between genome size and the phenotypic traits seed weight and length of the vegetative cycle. Moreover, cytological parameters such as the percentage of heterochromatin as well as the number, position and sequence composition of knobs were analysed and their relationships with 2C DNA values were explored. The populations analysed presented significant differences in 2C DNA amount, from 4.62 to 6.29 pg, representing 36.15 % of the inter-populational variation. Moreover, intra-populational genome size variation was found, varying from 1.08 to 1.63-fold. The variation in the percentage of knob heterochromatin as well as in the number, chromosome position and sequence composition of the knobs was detected among and within the populations. Although a positive relationship between genome size and the percentage of heterochromatin was observed, a significant correlation was not found. This confirms that other non-coding repetitive DNA sequences are contributing to the genome size variation. A positive relationship between DNA amount and the seed weight has been reported in a large number of species, this relationship was not found in the populations studied here. The length of the vegetative cycle showed a positive correlation with the percentage of heterochromatin. This result allowed attributing an adaptive effect to heterochromatin since the length of this cycle would be optimized via selection for an appropriate percentage of heterochromatin. PMID:26644343</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title26-vol2/pdf/CFR-2010-title26-vol2-sec1-61-11.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title26-vol2/pdf/CFR-2010-title26-vol2-sec1-61-11.pdf"><span>26 CFR 1.61-11 - Pensions.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-04-01</p> <p>... employee's contributions may constitute long-term capital gain, rather than ordinary income. (b) Cross... the Code and the regulations thereunder. Amounts received as pensions or annuities under the Social...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2011-title26-vol2/pdf/CFR-2011-title26-vol2-sec1-61-11.pdf','CFR2011'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2011-title26-vol2/pdf/CFR-2011-title26-vol2-sec1-61-11.pdf"><span>26 CFR 1.61-11 - Pensions.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2011&page.go=Go">Code of Federal Regulations, 2011 CFR</a></p> <p></p> <p>2011-04-01</p> <p>... employee's contributions may constitute long-term capital gain, rather than ordinary income. (b) Cross... the Code and the regulations thereunder. Amounts received as pensions or annuities under the Social...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24992492','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24992492"><span>Language structures used by kindergartners with cochlear implants: relationship to phonological awareness, lexical knowledge and hearing loss.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nittrouer, Susan; Sansom, Emily; Low, Keri; Rice, Caitlin; Caldwell-Tarr, Amanda</p> <p>2014-01-01</p> <p>Listeners use their knowledge of how language is structured to aid speech recognition in everyday communication. When it comes to children with congenital hearing loss severe enough to warrant cochlear implants (CIs), the question arises of whether these children can acquire the language knowledge needed to aid speech recognition, in spite of only having spectrally degraded signals available to them. That question was addressed in the present study. Specifically, there were three goals: (1) to compare the language structures used by children with CIs to those of children with normal hearing (NH); (2) to assess the amount of variance in the language measures explained by phonological awareness and lexical knowledge; and (3) to assess the amount of variance in the language measures explained by factors related to the hearing loss itself and subsequent treatment. Language samples were obtained and transcribed for 40 children who had just completed kindergarten: 19 with NH and 21 with CIs. Five measures were derived from Systematic Analysis of Language Transcripts: (1) mean length of utterance in morphemes, (2) number of conjunctions, excluding and, (3) number of personal pronouns, (4) number of bound morphemes, and (5) number of different words. Measures were also collected on phonological awareness and lexical knowledge. Statistics examined group differences, as well as the amount of variance in the language measures explained by phonological awareness, lexical knowledge, and factors related to hearing loss and its treatment for children with CIs. Mean scores of children with CIs were roughly one standard deviation below those of children with NH on all language measures, including lexical knowledge, matching outcomes of other studies. Mean scores of children with CIs were closer to two standard deviations below those of children with NH on two out of three measures of phonological awareness (specifically those related to phonemic structure). Lexical knowledge explained significant amounts of variance on three language measures, but only one measure of phonological awareness (sensitivity to word-final phonemic structure) explained any significant amount of unique variance beyond that, and on only one language measure (number of bound morphemes). Age at first implant, but no other factors related to hearing loss or its treatment, explained significant amounts of variance on the language measures, as well. In spite of early intervention and advances in implant technology, children with CIs are still delayed in learning language, but grammatical knowledge is less affected than phonological awareness. Because there was little contribution to language development measured for phonological awareness independent of lexical knowledge, it was concluded that children with CIs could benefit from intervention focused specifically on helping them learn language structures, in spite of the likely phonological deficits they experience as a consequence of having degraded inputs.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25446200','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25446200"><span>The roles of AMY1 copies and protein expression in human salivary α-amylase activity.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yang, Ze-Min; Lin, Jing; Chen, Long-Hui; Zhang, Min; Chen, Wei-Wen; Yang, Xiao-Rong</p> <p>2015-01-01</p> <p>Salivary α-amylase (sAA) activity has been extensively investigated in nutrition and psychology. But few studies were performed to assess the role played by sAA gene (AMY1) copies and protein expression in basal and stimulus-induced sAA activity. The sAA activity, amount and AMY1 copy number were determined from 184 saliva samples pre- and post-citric acid stimulation. Our findings showed that citric acid could induce significant increase in sAA activity, total sAA amount, and glycosylated sAA amount, among which the glycosylated sAA amount had the largest response. The correlation analysis showed that AMY1 copy number, total sAA amount and AMY1 copy number×total sAA amount had significantly positive and successively increasing correlations with sAA activity in unstimulated and stimulated saliva, respectively, and furthermore, we observed higher correlations in unstimulated saliva when compared with the corresponding correlations in stimulated saliva. We also observed significant correlations between glycosylated sAA amount and sAA activity in unstimulated and stimulated saliva, respectively. Interestingly, the correlations were higher in stimulated saliva than in unstimulated saliva, and the correlations between glycosylated sAA amount and sAA activity were higher than that of between total sAA amount and sAA activity in stimulated saliva. Moreover, total sAA amount ratio and glycosylated sAA amount ratio showed significantly positive correlation with sAA activity ratio. AMY1 copy number had no correlation with sAA activity ratio. These findings suggested that AMY1 copy number and sAA amount played crucial roles in sAA activity; however, the roles were attenuated after stimulation due to fortified release of glycosylated sAA. Copyright © 2014 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/7085298','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/7085298"><span>beta- and gamma-Comparative dose estimates on Enewetak Atoll.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Crase, K W; Gudiksen, P H; Robison, W L</p> <p>1982-05-01</p> <p>Enewetak Atoll is one of the Pacific atolls used for atmospheric testing of U.S. nuclear weapons. Beta dose and gamma-ray exposure measurements were made on two islands of the Enewetak Atoll during July-August 1976 to determine the beta and low energy gamma-contribution to the total external radiation doses to the returning Marshallese. Measurements were made at numerous locations with thermoluminescent dosimeters (TLD), pressurized ionization chambers, portable NaI detectors, and thin-window pancake GM probes. Results of the TLD measurements with and without a beta-attenuator indicate that approx. 29% of the total dose rate at 1 m in air is due to beta- or low energy gamma-contribution. The contribution at any particular site, however, is somewhat dependent on ground cover, since a minimal amount of vegetation will reduce it significantly from that over bare soil, but thick stands of vegetation have little effect on any further reductions. Integral 30-yr external shallow dose estimates for future inhabitants were made and compared with external dose estimates of a previous large scale radiological survey (En73). Integral 30-yr shallow external dose estimates are 25-50% higher than whole body estimates. Due to the low penetrating ability of the beta's or low energy gamma's, however, several remedial actions can be taken to reduce the shallow dose contribution to the total external dose.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1988BoLMe..45..209G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1988BoLMe..45..209G"><span>On the contribution of atmospheric moisture to dew formation</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Garratt, J. R.; Segal, M.</p> <p>1988-09-01</p> <p>The relative contributions of dewfall (a flux of water vapour from air to surface) and distillation (a flux of water vapour from soil to canopy) to dew formation on closed canopy and bare soil surfaces are assessed, and the dependence of dew amount upon wind speed, absolute temperature, atmospheric stability, relative humidity, soil characteristics and cloudiness, all of which are significant factors, is evaluated. Some of these evaluations provide refinements to similar ones given in Monteith (1961). High dewfall rates are usually ≲0.06 mm hr-1 over canopy or bare soil, though upon a canopy under soil-saturated and air-saturated conditions, rates of dew formation may reach 0.07 0.09 mm hr-1 with contributions from distillation. Various sets of observations are reanalyzed to illustrate the importance of the horizontal advection of moisture in the nocturnal boundary layer (NBL) to observed high rates of dew formation arising from the atmospheric contribution of water vapour (dewfall). These locally observed high dewfall rates must be the result of small-scale or mesoscale horizontal advection of moisture in the NBL, since the humidity changes within the typically shallow NBL required to balance the loss of water at the surface are not observed. Over extensive areas of uniform surface (horizontal scales ≫10 km), such continuously high dewfall rates could only be balanced by a local supply of atmospheric moisture since advection of moisture would necessarily be small.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_23 --> <div id="page_24" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="461"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016EnOp...48.1515G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016EnOp...48.1515G"><span>Resource-constrained scheduling with hard due windows and rejection penalties</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Garcia, Christopher</p> <p>2016-09-01</p> <p>This work studies a scheduling problem where each job must be either accepted and scheduled to complete within its specified due window, or rejected altogether. Each job has a certain processing time and contributes a certain profit if accepted or penalty cost if rejected. There is a set of renewable resources, and no resource limit can be exceeded at any time. Each job requires a certain amount of each resource when processed, and the objective is to maximize total profit. A mixed-integer programming formulation and three approximation algorithms are presented: a priority rule heuristic, an algorithm based on the metaheuristic for randomized priority search and an evolutionary algorithm. Computational experiments comparing these four solution methods were performed on a set of generated benchmark problems covering a wide range of problem characteristics. The evolutionary algorithm outperformed the other methods in most cases, often significantly, and never significantly underperformed any method.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014APS..MARF56002M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014APS..MARF56002M"><span>Polymer dynamics in turbulent flow</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Muthukumar, Murugappan</p> <p>2014-03-01</p> <p>Presence of dilute amounts of high-molecular weight polymers in liquids undergoing turbulent wall-bounded shear flows leads to significant drag reduction. There are two major proposed mechanisms of drag reduction in the literature. One is based on enhanced viscosity due to chain extension; the other is based on the assumption that elastic energy stored in polymer conformations is comparable to the kinetic energy in some eddies. Using the Navier-Stokes equation for the fluid and the Kirkwood-Riseman-Zimm equation for polymer chains, we have addressed the coupling between the near-wall turbulence dynamics and polymer dynamics. Our theoretical results show that the torque associated with polymer conformations contributes more significantly than the chain stretching and that the characteristic dimensions of polymer coils are much smaller than eddy sizes required for possible exchange of energy. We thus emphasize an additional mechanism to the existing two schools of thought in the search of an understanding of drag reduction.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17533886','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17533886"><span>Reversing the picture superiority effect: a speed-accuracy trade-off study of recognition memory.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Boldini, Angela; Russo, Riccardo; Punia, Sahiba; Avons, S E</p> <p>2007-01-01</p> <p>Speed-accuracy trade-off methods have been used to contrast single- and dual-process accounts of recognition memory. With these procedures, subjects are presented with individual test items and required to make recognition decisions under various time constraints. In three experiments, we presented words and pictures to be intentionally learned; test stimuli were always visually presented words. At test, we manipulated the interval between the presentation of each test stimulus and that of a response signal, thus controlling the amount of time available to retrieve target information. The standard picture superiority effect was significant in long response deadline conditions (i.e., > or = 2,000 msec). Conversely, a significant reverse picture superiority effect emerged at short response-signal deadlines (< 200 msec). The results are congruent with views suggesting that both fast familiarity and slower recollection processes contribute to recognition memory. Alternative accounts are also discussed.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/7990065','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/7990065"><span>Immediate-type hypersensitivity reactions and hypnosis: problems in methodology.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Laidlaw, T M; Richardson, D H; Booth, R J; Large, R G</p> <p>1994-08-01</p> <p>Hypnosis has been used to ameliorate skin test reactivity in studies dating back to the 1930s. This study using modern methodology and statistical analyses sets out to test the hypothesis that it was possible to decrease reactions to histamine by hypnotic suggestion. Five subjects, all asthmatic and untrained in hypnosis, were given three hypnotic sessions where they were asked to control their reactions to histamine administered by the Pepys technique to forearm skin. These sessions were to be compared with three non-hypnotic sessions. The flare sizes but not wheal sizes were found to be significantly reduced after the hypnosis sessions, compared to sessions without hypnosis. Skin temperature was correlated with the size of reactions. The day upon which the sessions took place contributed significant amounts of the remaining unexplained variance, giving rise to questions about what could cause these day to day changes.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15530927','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15530927"><span>High visibility safety apparel and nighttime conspicuity of pedestrians in work zones.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sayer, James R; Mefford, Mary Lynn</p> <p>2004-01-01</p> <p>Every year numerous occupational fatalities result from pedestrians being struck by motor vehicles intruding into work zones. Attributes of retroreflective personal safety garments on pedestrian conspicuity at night were assessed in a field study. Using instrumented vehicles on a closed track, participants drove through simulated work zones attempting to detect pedestrians located in the work zones. Configuration of the retroreflective trim, trim color, placement in the work zone, and driver age significantly affected pedestrian conspicuity. Intensity and the amount of retroreflective trim did not. Personal safety garments incorporating retroreflective trim significantly improve pedestrian conspicuity in work zones. The results emphasize the importance of retroreflective trim on personal safety garments, particularly if the trim is located on garment sleeves. We examine the design attributes that contribute to making a personal safety garment conspicuous. The results have implications regarding preferred garment designs, industry standards, and service life of personal safety garments.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.usgs.gov/wri/2002/4271/wri20024271.pdf','USGSPUBS'); return false;" href="https://pubs.usgs.gov/wri/2002/4271/wri20024271.pdf"><span>Case study for delineating a contributing area to a well in a fractured siliciclastic-bedrock aquifer near Lansdale, Pennsylvania</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Barton, Gary J.; Risser, Dennis W.; Galeone, Daniel G.; Goode, Daniel J.</p> <p>2003-01-01</p> <p>A supply well used by the North Penn Water Authority near Lansdale, Pa., was selected as a case study for delineating a contributing area in a fractured siliciclastic-bedrock aquifer. The study emphasized the importance of refining the understanding of factors that control ground-water movement to the well by conducting (1) geophysical logging and flow measurements, (2) ground-water level monitoring, (3) aquifer testing, and (4) geochemical sampling. This approach could be applicable for other wells in siliciclastic-bedrock terranes, especially those of Triassic age in southeastern Pennsylvania.The principal methods for refining the understanding of hydrology at supply well MG-1125 were aquifer testing, water-level measurements, and geophysical logging. Results of two constant-discharge aquifer tests helped estimate the transmissivity of water-producing units and evaluate the anisotropy caused by dipping beds. Results from slug tests provided estimates of transmissivity that were used to evaluate the results from the constant-discharge aquifer tests. Slug tests also showed the wide distribution of transmissivity, indicating that ground-water velocities must vary considerably in the well field. Water-level monitoring in observation wells allowed maps of the potentiometric surface near the well field to be drawn. The measurements also showed that the hydraulic gradient can change abruptly in response to pumping from nearby supply wells. Water levels measured at a broader regional scale in an earlier study also provided a useful view of the potentiometric surface for purposes of delineating the contributing area. Geophysical logging and measurements of flow within wells showed that about 60 percent of water from supply well MG-1125 probably is contributed from relatively shallow water-producing fractures from 60 to 125 feet below land surface, but measurable amounts of water are contributed by fractures to a depth of 311 feet below land surface. Chemical samples supported the evidence that shallow fractures probably contribute significant amounts of water to well MG-1125. The large contribution of water from shallow fractures indicates that the area providing part of the recharge to the well is not far removed from the wellhead.Preliminary delineations of the contributing area and the 100-day time-of travel area were computed from a water budget and time-of-travel equation. These delineations provided insight into the size (but not the shape) of the contributing areas. Three other approaches were used and results compared: (1) uniform-flow equation, (2) hydrogeologic mapping, and (3) numerical modeling. The uniform-flow equation predicted a contributing area that seemed unrealistic—extending far across the ground-water divide into an adjacent watershed. Hydrogeologic mapping, if used with the potentiometric surface and constrained by the water budget, produced contributing area that was similar to that from numerical modeling. Numerical modeling allowed the incorporation of anisotropy caused by dipping water-producing units, differing transmissivity values of geologic units, and ground-water withdrawals from nearby supply wells. The numerical modeling showed that groundwater withdrawals from nearby supply wells affected the contributing area to supply well MG-1125 but had less effect on the 100-day time-of-travel area.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20070019373&hterms=tb&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D90%26Ntt%3Dtb','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20070019373&hterms=tb&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D90%26Ntt%3Dtb"><span>Percentage Contributions from Atmospheric and Surface Features to Computed Brightness Temperatures</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Jackson, Gail Skofronick</p> <p>2006-01-01</p> <p>Over the past few years, there has become an increasing interest in the use of millimeter-wave (mm-wave) and sub-millimeter-wave (submm-wave) radiometer observations to investigate the properties of ice particles in clouds. Passive radiometric channels respond to both the integrated particle mass throughout the volume and field of view, and to the amount, location, and size distribution of the frozen (and liquid) particles with the sensitivity varying for different frequencies and hydrometeor types. One methodology used since the 1960's to discern the relationship between the physical state observed and the brightness temperature (TB) is through the temperature weighting function profile. In this research, the temperature weighting function concept is exploited to analyze the sensitivity of various characteristics of the cloud profile, such as relative humidity, ice water path, liquid water path, and surface emissivity. In our numerical analysis, we compute the contribution (in Kelvin) from each of these cloud and surface characteristics, so that the sum of these various parts equals the computed TB. Furthermore, the percentage contribution from each of these characteristics is assessed. There is some intermingling/contamination of the contributions from various components due to the integrated nature of passive observations and the absorption and scattering between the vertical layers, but all in all the knowledge gained is useful. This investigation probes the sensitivity over several cloud classifications, such as cirrus, blizzards, light snow, anvil clouds, and heavy rain. The focus is on mm-wave and submm-wave frequencies, however discussions of the effects of cloud variations to frequencies as low as 10 GHz and up to 874 GHz will also be presented. The results show that nearly 60% of the TB value at 89 GHz comes from the earth's surface for even the heaviest blizzard snow rates. On the other hand, a significant percentage of the TB value comes from the snow in the cloud for 166, and 183 plus or minus 7 GHz for the heavy and medium snow rates. For submm-wave channels, there is no contribution from the surface because these channels cannot probe through clouds, nor normal water vapor amounts in clear air regions. This work is extremely valuable in physically-based retrieval algorithm development research.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12838052','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12838052"><span>Orthopaedic research and education foundation and industry.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wurth, Gene R; Sherr, Judy H; Coffman, Thomas M</p> <p>2003-07-01</p> <p>Members of orthopaedic industry commit a significant amount of funds each year to support research and education programs that are directly related to their product(s). In addition, industry supports organizations such as the Orthopaedic Research and Education Foundation. The relationship between the Orthopaedic Research and Education Foundation and industry began in the early 1980s. The support to the Orthopaedic Research and Education Foundation from industry primarily has come in the form of unrestricted grants. These grants best can be looked at as an investment rather than a contribution. This form of giving, once called corporate philanthropy is more accurately referred to as strategic philanthropy. Members of industry make these investments to enhance their reputations, build brand awareness, market their products and services, improve employee morale, increase customer loyalty, and establish strategic alliances. The specialty of orthopaedics is among the leaders in medicine in the amount of funding raised within the specialty for research and education programs. This is because of the amount of support from members of industry and the surgeons. During the past 15 years, 40% of the annual support to the Orthopaedic Research and Education Foundation has come from industry and the balance has come from surgeons and members of lay public. Future industry support of the Orthopaedic Research and Education Foundation and other organizations within the specialty of orthopaedics will be dependent on the continued demonstration of tangible returns in areas described.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JGRD..122.5808Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JGRD..122.5808Z"><span>Wetting and greening Tibetan Plateau in early summer in recent decades</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Zhang, Wenxia; Zhou, Tianjun; Zhang, Lixia</p> <p>2017-06-01</p> <p>The Tibetan Plateau (TP) plays an essential role in the global hydrological cycle. Unlike the well-recognized surface warming, changes in precipitation over the TP and the underlying mechanisms remain ambiguous. A significant increase in the amount of precipitation over the southeastern TP in May over 1979-2014 (13.46% decade-1 of the climatology) is identified in this study, based on homogenized daily rain gauge data. Both the increased precipitation frequency and intensity have contributions. The coherent increases in soil moisture content and vegetation activities further confirm the precipitation trend, indicating a wetting and greening TP in the early summer in recent decades. The moisture budget analysis shows that this wetting trend in the past four decades is dominated by the increased water vapor convergence due to circulation changes, while increases in specific humidity play a minor role. The wetting trend over the TP in May results directly from the earlier onset of the South Asian summer monsoon (ASM) since the late 1970s associated with the phase transition of Interdecadal Pacific Oscillation around the late 1990s. The earlier onset of the ASM triggers low-level southwesterly anomalies over the northern Indian Ocean, promoting moisture convergence and increased precipitation over the TP in May. Specifically, the increased amount of precipitation after the onset of the ASM explains 95% of the increase in the total amount of precipitation in May.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JGRB..122.4089P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JGRB..122.4089P"><span>Bottom-simulating reflector dynamics at Arctic thermogenic gas provinces: An example from Vestnesa Ridge, offshore west Svalbard</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Plaza-Faverola, A.; Vadakkepuliyambatta, S.; Hong, W.-L.; Mienert, J.; Bünz, S.; Chand, S.; Greinert, J.</p> <p>2017-06-01</p> <p>The Vestnesa Ridge comprises a >100 km long sediment drift located between the western continental slope of Svalbard and the Arctic mid-ocean ridges. It hosts a deep water (>1000 m) gas hydrate and associated seafloor seepage system. Near-seafloor headspace gas compositions and its methane carbon isotopic signature along the ridge indicate a predominance of thermogenic gas sources feeding the system. Prediction of the base of the gas hydrate stability zone for theoretical pressure and temperature conditions and measured gas compositions results in an unusual underestimation of the observed bottom-simulating reflector (BSR) depth. The BSR is up to 60 m deeper than predicted for pure methane and measured gas compositions with >99% methane. Models for measured gas compositions with >4% higher-order hydrocarbons result in a better BSR approximation. However, the BSR remains >20 m deeper than predicted in a region without active seepage. A BSR deeper than predicted is primarily explained by unaccounted spatial variations in the geothermal gradient and by larger amounts of thermogenic gas at the base of the gas hydrate stability zone. Hydrates containing higher-order hydrocarbons form at greater depths and higher temperatures and contribute with larger amounts of carbons than pure methane hydrates. In thermogenic provinces, this may imply a significant upward revision (up to 50% in the case of Vestnesa Ridge) of the amount of carbon in gas hydrates.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1342283-changes-temporal-variability-precipitation-over-land-due-anthropogenic-forcings','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1342283-changes-temporal-variability-precipitation-over-land-due-anthropogenic-forcings"><span>Changes in temporal variability of precipitation over land due to anthropogenic forcings</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Konapala, Goutam; Mishra, Ashok; Leung, L. Ruby</p> <p>2017-02-02</p> <p>This study investigated the anthropogenic influence on the temporal variability of annual precipitation for the period 1950-2005 as simulated by the CMIP5 models. The temporal variability of both annual precipitation amount (PRCPTOT) and intensity (SDII) was first measured using a metric of statistical dispersion called the Gini coefficient. Comparing simulations driven by both anthropogenic and natural forcings (ALL) with simulations of natural forcings only (NAT), we quantified the anthropogenic contributions to the changes in temporal variability at global, continental and sub-continental scales as a relative difference of the respective Gini coefficients of ALL and NAT. Over the period of 1950-2005,more » our results indicate that anthropogenic forcings have resulted in decreased uniformity (i.e., increase in unevenness or disparity) in annual precipitation amount and intensity at global as well as continental scales. In addition, out of the 21 sub-continental regions considered, 14 (PRCPTOT) and 17 (SDII) regions showed significant anthropogenic influences. The human impacts are generally larger for SDII compared to PRCTOT, indicating that the temporal variability of precipitation intensity is generally more susceptible to anthropogenic influence than precipitation amount. Lastly, the results highlight that anthropogenic activities have changed not only the trends but also the temporal variability of annual precipitation, which underscores the need to develop effective adaptation management practices to address the increased disparity.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26017273','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26017273"><span>Delay and probability discounting of sexual and monetary outcomes in individuals with cocaine use disorders and matched controls.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Johnson, Matthew W; Johnson, Patrick S; Herrmann, Evan S; Sweeney, Mary M</p> <p>2015-01-01</p> <p>Individuals with cocaine use disorders are disproportionately affected by HIV/AIDS, partly due to higher rates of unprotected sex. Recent research suggests delay discounting of condom use is a factor in sexual HIV risk. Delay discounting is a behavioral economic concept describing how delaying an event reduces that event's value or impact on behavior. Probability discounting is a related concept describing how the uncertainty of an event decreases its impact on behavior. Individuals with cocaine use disorders (n = 23) and matched non-cocaine-using controls (n = 24) were compared in decision-making tasks involving hypothetical outcomes: delay discounting of condom-protected sex (Sexual Delay Discounting Task), delay discounting of money, the effect of sexually transmitted infection (STI) risk on likelihood of condom use (Sexual Probability Discounting Task), and probability discounting of money. The Cocaine group discounted delayed condom-protected sex (i.e., were more likely to have unprotected sex vs. wait for a condom) significantly more than controls in two of four Sexual Delay Discounting Task partner conditions. The Cocaine group also discounted delayed money (i.e., preferred smaller immediate amounts over larger delayed amounts) significantly more than controls. In the Sexual Probability Discounting Task, both groups showed sensitivity to STI risk, however the groups did not differ. The Cocaine group did not consistently discount probabilistic money more or less than controls. Steeper discounting of delayed, but not probabilistic, sexual outcomes may contribute to greater rates of sexual HIV risk among individuals with cocaine use disorders. Probability discounting of sexual outcomes may contribute to risk of unprotected sex in both groups. Correlations showed sexual and monetary results were unrelated, for both delay and probability discounting. The results highlight the importance of studying specific behavioral processes (e.g., delay and probability discounting) with respect to specific outcomes (e.g., monetary and sexual) to understand decision making in problematic behavior.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4445907','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4445907"><span>Delay and Probability Discounting of Sexual and Monetary Outcomes in Individuals with Cocaine Use Disorders and Matched Controls</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Johnson, Matthew W.; Johnson, Patrick S.; Herrmann, Evan S.; Sweeney, Mary M.</p> <p>2015-01-01</p> <p>Individuals with cocaine use disorders are disproportionately affected by HIV/AIDS, partly due to higher rates of unprotected sex. Recent research suggests delay discounting of condom use is a factor in sexual HIV risk. Delay discounting is a behavioral economic concept describing how delaying an event reduces that event’s value or impact on behavior. Probability discounting is a related concept describing how the uncertainty of an event decreases its impact on behavior. Individuals with cocaine use disorders (n = 23) and matched non-cocaine-using controls (n = 24) were compared in decision-making tasks involving hypothetical outcomes: delay discounting of condom-protected sex (Sexual Delay Discounting Task), delay discounting of money, the effect of sexually transmitted infection (STI) risk on likelihood of condom use (Sexual Probability Discounting Task), and probability discounting of money. The Cocaine group discounted delayed condom-protected sex (i.e., were more likely to have unprotected sex vs. wait for a condom) significantly more than controls in two of four Sexual Delay Discounting Task partner conditions. The Cocaine group also discounted delayed money (i.e., preferred smaller immediate amounts over larger delayed amounts) significantly more than controls. In the Sexual Probability Discounting Task, both groups showed sensitivity to STI risk, however the groups did not differ. The Cocaine group did not consistently discount probabilistic money more or less than controls. Steeper discounting of delayed, but not probabilistic, sexual outcomes may contribute to greater rates of sexual HIV risk among individuals with cocaine use disorders. Probability discounting of sexual outcomes may contribute to risk of unprotected sex in both groups. Correlations showed sexual and monetary results were unrelated, for both delay and probability discounting. The results highlight the importance of studying specific behavioral processes (e.g., delay and probability discounting) with respect to specific outcomes (e.g., monetary and sexual) to understand decision making in problematic behavior. PMID:26017273</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/11334157','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/11334157"><span>Solid waste treatment as a high-priority and low-cost alternative for greenhouse gas mitigation.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ayalon, O; Avnimelech, Y; Shechter, M</p> <p>2001-05-01</p> <p>The increased concern about environmental problems caused by inadequate waste management, as well as the concern about global warming, promotes actions toward a sustainable management of the organic fraction of the waste. Landfills, the most common means to dispose of municipal solid waste (MSW), lead to the conversion of the organic waste to biogas, containing about 50% methane, a very active greenhouse gas (GHG). One unit of methane has a global warming potential of 21 computed for a 100-year horizon or 56 computed for 20 years. The waste sector in Israel contributes 13% of total greenhouse gases (GHG) emissions for a time horizon of 100 years (for a time horizon of 20 years, the waste sector contribution equals to more than 25% of total GHG emissions). The ultimate goal is to minimize the amount of methane (CH4) by converting it to CO2. This can be achieved by physicochemical means (e.g., landfill gas flare, incineration) or by biological processes (e.g., composting, anaerobic digestion). Since the waste in Israel has a high organic material content, it was found that the most cost-effective means to treat the degradable organic components is by aerobic composting (investment of less than US$ 10 to reduce emission of one ton CO2 equivalent per year). Another benefit of this technology is the ability to implement it within a short period. The suggested approach, which should be implemented especially in developing countries, could reduce a significant amount of GHG at relatively low cost and short time. The development of a national policy for proper waste treatment can be a significant means to abate GHG emissions in the short term, enabling a gain in time to develop other means for the long run. In addition, the use of CO2 quotas will credit the waste sector and will promote profitable proper waste management.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22296285','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22296285"><span>Kinetics and thermodynamics of chlorpromazine interaction with lipid bilayers: effect of charge and cholesterol.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Martins, Patrícia T; Velazquez-Campoy, Adrian; Vaz, Winchil L C; Cardoso, Renato M S; Valério, Joana; Moreno, Maria João</p> <p>2012-03-07</p> <p>Passive transport across cell membranes is the major route for the permeation of xenobiotics through tight endothelia such as the blood–brain barrier. The rate of passive permeation through lipid bilayers for a given drug is therefore a critical step in the prediction of its pharmacodynamics. We describe a detailed study on the kinetics and thermodynamics for the interaction of chlorpromazine (CPZ), an antipsychotic drug used in the treatment of schizophrenia, with neutral and negatively charged lipid bilayers. Isothermal titration calorimetry was used to study the partition and translocation of CPZ in lipid membranes composed of pure POPC, POPC:POPS (9:1), and POPC:Chol:POPS (6:3:1). The membrane charge due to the presence of POPS as well as the additional charge resulting from the introduction of CPZ in the membrane were taken into account, allowing the calculation of the intrinsic partition coefficients (K(P)) and the enthalpy change (ΔH) associated with the process. The enthalpy change upon partition to all lipid bilayers studied is negative, but a significant entropy contribution was also observed for partition to the neutral membrane. Because of the positive charge of CPZ, the presence of negatively charged lipids in the bilayer increases both the observed amount of CPZ that partitions to the membrane (KP(obs)) and the magnitude of ΔH. However, when the electrostatic effects are discounted, the intrinsic partition coefficient was smaller, indicating that the hydrophobic contribution was less significant for the negatively charged membrane. The presence of cholesterol strongly decreases the affinity of CPZ for the bilayer in terms of both the amount of CPZ that associates with the membrane and the interaction enthalpy. A quantitative characterization of the rate of CPZ translocation through membranes composed of pure POPC and POPC:POPS (9:1) was also performed using an innovative methodology developed in this work based on the kinetics of the heat evolved due to the interaction of CPZ with the membranes. © 2012 American Chemical Society</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/3426687','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/3426687"><span>Pavlovian conditioning and ethanol tolerance.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Siegel, S</p> <p>1987-01-01</p> <p>Results of considerable amount of research indicate that Pavlovian conditional pharmacological responses, resulting from repeated pairings of ethanol-associated environmental cues with the systemic effects of ethanol, importantly contribute to ethanol tolerance.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23498100','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23498100"><span>Foods and beverages associated with higher intake of sugar-sweetened beverages.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mathias, Kevin C; Slining, Meghan M; Popkin, Barry M</p> <p>2013-04-01</p> <p>Although consumption of sugar-sweetened beverages (SSBs) is associated with higher caloric intakes, the amount SSBs contribute to higher intakes has not been addressed. To estimate the amount SSBs contribute to higher caloric intakes and determine how the diets of SSB consumers and nonconsumers differ. The What We Eat In America, NHANES 2003-2010 surveys were combined into a sample of 13,421 children; analyses were conducted in December 2012. To determine the contribution of SSBs to higher caloric intakes, total non-SSB intake (food + non-SSB beverages) of SSB consumers and nonconsumers were compared using linear regression models controlling for demographic and socioeconomic factors. Analyses also compared intakes between nonconsumers and SSB consumers with different amounts of SSB consumption. For children aged 2-5 years and 6-11 years, total non-SSB intakes did not differ between nonconsumers and SSB consumers at any level of SSB consumption, indicating that SSBs were primarily responsible for the higher caloric intakes among SSB consumers. A similar finding was observed among children aged 12-18 years; however, both food and SSB contributed to higher caloric intakes of adolescents consuming ≥500 kcal of SSBs. Among those aged 12-18 years, higher intakes of foods (e.g., pizza, burgers, fried potatoes, and savory snacks) and lower intakes of non-SSB beverages (e.g., fluid milk and fruit juice) were associated with increased SSB intake. Sugar-sweetened beverages are primarily responsible for the higher caloric intakes of SSB consumers, and SSB consumption is associated with intake of a select number of food and beverage groups, some of which are often unhealthy (e.g., pizza and grain-based desserts). Copyright © 2013 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/865525','DOE-PATENT-XML'); return false;" href="https://www.osti.gov/servlets/purl/865525"><span>Method for fabricating wrought components for high-temperature gas-cooled reactors and product</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/doepatents">DOEpatents</a></p> <p>Thompson, Larry D.; Johnson, Jr., William R.</p> <p>1985-01-01</p> <p>A method and alloys for fabricating wrought components of a high-temperature gas-cooled reactor are disclosed. These wrought, nickel-based alloys, which exhibit strength and excellent resistance to carburization at elevated temperatures, include aluminum and titanium in amounts and ratios to promote the growth of carburization resistant films while preserving the wrought character of the alloys. These alloys also include substantial amounts of molybdenum and/or tungsten as solid-solution strengtheners. Chromium may be included in concentrations less than 10% to assist in fabrication. Minor amounts of carbon and one or more carbide-forming metals also contribute to high-temperature strength.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5855857','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5855857"><span>The In Vitro Effects of Enzymatic Digested Gliadin on the Functionality of the Autophagy Process</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Manai, Federico; Azzalin, Alberto; Gabriele, Fabio; Martinelli, Carolina; Morandi, Martina; Comincini, Sergio</p> <p>2018-01-01</p> <p>Gliadin, the alcohol-soluble protein fraction of wheat, contains the factor toxic for celiac disease (CD), and its toxicity is not reduced by digestion with gastro-pancreatic enzymes. Importantly, it is proved that an innate immunity to gliadin plays a key role in the development of CD. The immune response induces epithelial stress and reprograms intraepithelial lymphocytes into natural killer (NK)-like cells, leading to enterocyte apoptosis and an increase in epithelium permeability. In this contribution, we have reported that in Caco-2 cells the administration of enzymatically digested gliadin (PT-gliadin) reduced significantly the expression of the autophagy-related marker LC3-II. Furthermore, electron and fluorescent microscope analysis suggested a compromised functionality of the autophagosome apparatus. The rescue of the dysregulated autophagy process, along with a reduction of PT-gliadin toxicity, was obtained with a starvation induction protocol and by 3-methyladenine administration, while rapamycin, a well-known autophagy inducer, did not produce a significant improvement in the clearance of extra- and intra-cellular fluorescent PT-gliadin amount. Altogether, our results highlighted the possible contribution of the autophagy process in the degradation and in the reduction of extra-cellular release of gliadin peptides and suggest novel molecular targets to counteract gliadin-induced toxicity in CD. PMID:29473905</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28199942','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28199942"><span>Atmospheric contribution to boron enrichment in aboveground wheat tissues.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wang, Cheng; Ji, Junfeng; Chen, Mindong; Zhong, Cong; Yang, Zhongfang; Browne, Patrick</p> <p>2017-05-01</p> <p>Boron is an essential trace element for all organisms and has both beneficial and harmful biological functions. A particular amount of boron is discharged into the environment every year because of industrial activities; however, the effects of environmental boron emissions on boron accumulation in cereals has not yet been estimated. The present study characterized the accumulation of boron in wheat under different ecological conditions in the Yangtze River Delta (YRD) area. This study aimed to estimate the effects of atmospheric boron that is associated with industrial activities on boron accumulation in wheat. The results showed that the concentrations of boron in aboveground wheat tissues from the highly industrialized region were significantly higher than those from the agriculture-dominated region, even though there was no significant difference in boron content in soils. Using the model based on the translocation coefficients of boron in the soil-wheat system, we estimated that the contribution of atmosphere to boron accumulation in wheat straw in the highly industrialized region exceeded that in the agriculture-dominated region by 36%. In addition, from the environmental implication of the model, it was estimated that the development of boron-utilizing industries had elevated the concentration of boron in aboveground wheat tissues by 28-53%. Copyright © 2017 Elsevier Ltd. All rights reserved.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_24 --> <div id="page_25" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="481"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23523576','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23523576"><span>Previous contact with Strongyloides venezuelensis contributed to prevent insulitis in MLD-STZ diabetes.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Peres, Raphael Sanches; Chiuso-Minicucci, Fernanda; da Rosa, Larissa Camargo; Domingues, Alexandre; Zorzella-Pezavento, Sofia Fernanda Gonçalves; França, Thais Graziela Donegá; Ishikawa, Larissa Lumi Watanabe; do Amarante, Alessandro Francisco Talamini; Sartori, Alexandrina</p> <p>2013-06-01</p> <p>Epidemiological and experimental studies support the idea that helminth infections can induce a protective effect against the development of autoimmune and allergic diseases. In this study we characterized the immune response induced by Strongyloides venezuelensis infection in C57BL/6 mice and then evaluated the effect of a previous contact with this helminth in the outcome of type 1 diabetes. Animals were initially infected with 2000 L3 larvae from S. venezuelensis and euthanized 22 days later. An acute phase, identified by a high amount of eggs per gram of feces, was established between days 7 and 9 post-infection. Recovery from infection was associated with a Th2 polarized response characterized by a significant level of serum IgG1 specific antibodies and also a significant production of IL-5 and IL-10 by spleen cells stimulated with S. venezuelensis soluble antigen. Immunization with soluble S. venezuelensis antigen associated with complete Freund's adjuvant followed by infection with S. venezuelensis protected mice from diabetes development induced by streptozotocin. Protection was characterized by a higher body weight gain, lower glycemic levels, much less severe insulitis and preserved insulin production. Together, these results indicate that S. venezuelensis contributed to protect C57BL/6 mice against experimental diabetes induced by streptozotocin. Copyright © 2013 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10827307','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10827307"><span>Equity in the financing of social security for health in Chile.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bitran, R; Mu?oz, J; Aguad, P; Navarrete, M; Ubilla, G</p> <p>2000-01-01</p> <p>Real public health spending has more than doubled since 1990, raising concerns about the targeting of public subsidies. This study examined the degree of equity in the financing of FONASA, the public insurer, which in 1995 covered 8.6 million beneficiaries, or 62% of the country's population. Study results, covering calendar year 1995, indicated that (1) government health subsidies were well-targeted, with about 90% reaching the indigent and 8% going to other, low-income beneficiaries; (2) only 2.5% of government subsidies leaked to higher-income, non-beneficiaries of FONASA (people covered by private insurers known as ISAPRES, otherwise covered, or without any coverage); (3) overall, FONASA's contributing beneficiaries (i.e. the indigent aside) self-financed their health benefits, although higher-income beneficiaries were providing significant cross-subsidies to low-income ones, making the internal financing of FONASA somewhat progressive; (4) the indigent received the highest amount of annual net benefits per capita, followed by low-income beneficiaries; and (5) the evasion of FONASA's payroll tax was pervasive, although public providers delivered care on an equal basis irrespective of the patients' contributions to FONASA. FONASA's finances would improve significantly if affiliation to health social security by both dependent and independent workers was made compulsory.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28411577','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28411577"><span>Perceived parental child rearing and attachment as predictors of anxiety and depressive disorder symptoms in children: The mediational role of attachment.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chorot, Paloma; Valiente, Rosa M; Magaz, Ana M; Santed, Miguel A; Sandin, Bonifacio</p> <p>2017-07-01</p> <p>The present study aimed to examine (a) the relative contribution of perceived parental child-rearing behaviors and attachment on anxiety and depressive symptoms, and (b) the role of attachment as a possible mediator of the association between parental rearing and anxiety and depression. A sample of 1002 children (aged 9-12 years) completed a booklet of self-report questionnaires measuring parental rearing behaviors, attachment towards peers, and DSM anxiety and depressive disorder symptoms. We found that parental aversiveness, parental neglect, and fearful/preoccupied attachment, each accounted for a significant amount of the variance in both anxiety and depressive symptoms. In addition, parental overcontrol was found to account for unique variance in anxiety whereas communication/warmth accounted for a significant proportion of the variance in depression. A relevant finding was that fearful/preoccupied attachment was found to mediate the association between parental rearing behaviors and both anxiety and depression. Parental rearing behaviors and attachment to peers may act as risk factors to the development and/or maintenance of anxiety and depressive symptomatology in children. Findings may contribute to outline preventive and/or treatment programs to prevent or reduce both clinical anxiety and depression during childhood. Copyright © 2017. Published by Elsevier B.V.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1985MTA....16.2023S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1985MTA....16.2023S"><span>A theoretical model for the flow behavior of commercial dual-phase steels containing metastable retained austenite: Part II. calculation of flow curves</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sangal, Sandeep; Goel, Naresh C.; Tangri, Kris</p> <p>1985-11-01</p> <p>The role of metastable retained austenite (γ R), its volume fraction, and mechanical stability on the flow characteristics of a dual phase steel containing 20 vol pct of ‘as quenched’ martensite in a ferrite matrix has been examined in this paper employing the flow curve expressions derived in Part I of this paper. It has been found that for a given volume fraction of γ R, its mechanical stability plays a crucial role in enhancing the ductility. Whereas highly stable γ R does not contribute either to strength or ductility of the steel, highly unstable γ R which causes an increase in the strength is detrimental to ductility. A γ R which is moderately stable and undergoes γ R → α' transformation over a larger strain range is beneficial to enhanced ductility. Increasing amounts of moderately stable γ R significantly increase both the strength and the ductility of dual-phase steels through a sustained work-hardening due to γ R → α' transformation. Load transfer which is determined by a parameter q has a significant contribution to work-hardening. A value of ∣|q∣| = 4500 MPa has been found to partition realistically the stress and strain in these steels.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25876662','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25876662"><span>Contribution of extracellular ATP on the cell-surface F1F0-ATP synthase-mediated intracellular triacylglycerol accumulation.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kita, Toshiyuki; Arakaki, Naokatu</p> <p>2015-01-01</p> <p>Cell-surface F1F0-ATP synthase was involved in the cell signaling mediating various biological functions. Recently, we found that cell-surface F1F0-ATP synthase plays a role on intracellular triacylglycerol accumulation in adipocytes, and yet, the underlying mechanisms remained largely unknown. In this study, we investigated the role of extracellular ATP on the intracellular triacylglycerol accumulation. We demonstrated that significant amounts of ATP were produced extracellularly by cultured 3T3-L1 adipocytes and that the antibodies against α and β subunits of F1F0-ATP synthase inhibited the extracellular ATP production. Piceatannol, a F1F0-ATP synthase inhibitor, and apyrase, an enzyme which degrades extracellular ATP, suppressed triacylglycerol accumulation. The selective P2Y1 receptor antagonist MRS2500 significantly inhibited triacylglycerol accumulation, whereas the selective P2X receptor antagonist NF279 has less effect. The present results indicate that cell-surface F1F0-ATP synthase on adipocytes is functional in extracellular ATP production and that the extracellular ATP produced contributes, at least in part, to the cell-surface F1F0-ATP synthase-mediated intracellular triacylglycerol accumulation in adipocytes through P2Y1 receptor.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70190380','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70190380"><span>Methane hydrate-bearing seeps as a source of aged dissolved organic carbon to the oceans</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Pohlman, John; Waite, William F.; Bauer, James E.; Osburn, Christopher L.; Chapman, N. Ross</p> <p>2011-01-01</p> <p>Marine sediments contain about 500–10,000 Gt of methane carbon1, 2, 3, primarily in gas hydrate. This reservoir is comparable in size to the amount of organic carbon in land biota, terrestrial soils, the atmosphere and sea water combined1, 4, but it releases relatively little methane to the ocean and atmosphere5. Sedimentary microbes convert most of the dissolved methane to carbon dioxide6, 7. Here we show that a significant additional product associated with microbial methane consumption is methane-derived dissolved organic carbon. We use Δ14C and δ13C measurements and isotopic mass-balance calculations to evaluate the contribution of methane-derived carbon to seawater dissolved organic carbon overlying gas hydrate-bearing seeps in the northeastern Pacific Ocean. We show that carbon derived from fossil methane accounts for up to 28% of the dissolved organic carbon. This methane-derived material is much older, and more depleted in 13C, than background dissolved organic carbon. We suggest that fossil methane-derived carbon may contribute significantly to the estimated 4,000–6,000 year age of dissolved organic carbon in the deep ocean8, and provide reduced organic matter and energy to deep-ocean microbial communities.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4286420','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4286420"><span>Visual-spatial abilities relate to mathematics achievement in children with heavy prenatal alcohol exposure</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Crocker, N.; Riley, E.P.; Mattson, S.N.</p> <p>2014-01-01</p> <p>Objective The current study examined the relationship between mathematics and attention, working memory, and visual memory in children with heavy prenatal alcohol exposure and controls. Method Fifty-six children (29 AE, 27 CON) were administered measures of global mathematics achievement (WRAT-3 Arithmetic & WISC-III Written Arithmetic), attention, (WISC-III Digit Span forward and Spatial Span forward), working memory (WISC-III Digit Span backward and Spatial Span backward), and visual memory (CANTAB Spatial Recognition Memory and Pattern Recognition Memory). The contribution of cognitive domains to mathematics achievement was analyzed using linear regression techniques. Attention, working memory and visual memory data were entered together on step 1 followed by group on step 2, and the interaction terms on step 3. Results Model 1 accounted for a significant amount of variance in both mathematics achievement measures, however, model fit improved with the addition of group on step 2. Significant predictors of mathematics achievement were Spatial Span forward and backward and Spatial Recognition Memory. Conclusions These findings suggest that deficits in spatial processing may be related to math impairments seen in FASD. In addition, prenatal alcohol exposure was associated with deficits in mathematics achievement, above and beyond the contribution of general cognitive abilities. PMID:25000323</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25000323','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25000323"><span>Visual-spatial abilities relate to mathematics achievement in children with heavy prenatal alcohol exposure.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Crocker, Nicole; Riley, Edward P; Mattson, Sarah N</p> <p>2015-01-01</p> <p>The current study examined the relationship between mathematics and attention, working memory, and visual memory in children with heavy prenatal alcohol exposure and controls. Subjects were 56 children (29 AE, 27 CON) who were administered measures of global mathematics achievement (WRAT-3 Arithmetic & WISC-III Written Arithmetic), attention, (WISC-III Digit Span forward and Spatial Span forward), working memory (WISC-III Digit Span backward and Spatial Span backward), and visual memory (CANTAB Spatial Recognition Memory and Pattern Recognition Memory). The contribution of cognitive domains to mathematics achievement was analyzed using linear regression techniques. Attention, working memory, and visual memory data were entered together on Step 1 followed by group on Step 2, and the interaction terms on Step 3. Model 1 accounted for a significant amount of variance in both mathematics achievement measures; however, model fit improved with the addition of group on Step 2. Significant predictors of mathematics achievement were Spatial Span forward and backward and Spatial Recognition Memory. These findings suggest that deficits in spatial processing may be related to math impairments seen in FASD. In addition, prenatal alcohol exposure was associated with deficits in mathematics achievement, above and beyond the contribution of general cognitive abilities. PsycINFO Database Record (c) 2015 APA, all rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title11-vol1/pdf/CFR-2010-title11-vol1-sec104-22.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title11-vol1/pdf/CFR-2010-title11-vol1-sec104-22.pdf"><span>11 CFR 104.22 - Disclosure of bundling by Lobbyists/Registrants and Lobbyist/Registrant PACs (2 U.S.C. 434(i)).</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-01-01</p> <p>... assigns to persons who have raised a certain amount of contributions; (2) Tracking identifiers that the... ELECTION COMMISSION GENERAL REPORTS BY POLITICAL COMMITTEES AND OTHER PERSONS (2 U.S.C. 434) § 104.22... means a person who, at the time a contribution is forwarded to, or is received by, a reporting committee...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2014-title26-vol5/pdf/CFR-2014-title26-vol5-sec1-401a4-2.pdf','CFR2014'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2014-title26-vol5/pdf/CFR-2014-title26-vol5-sec1-401a4-2.pdf"><span>26 CFR 1.401(a)(4)-2 - Nondiscrimination in amount of employer contributions under a defined contribution plan.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2014&page.go=Go">Code of Federal Regulations, 2014 CFR</a></p> <p></p> <p>2014-04-01</p> <p>... greater of the allocations under two or more formulas, one of which is a top-heavy formula, the top-heavy... is the greater of the allocations under two or more formulas, and one or more of those formulas is... provide uniform allocations are permitted to satisfy this requirement by meeting one of the safe harbors...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2012-title26-vol5/pdf/CFR-2012-title26-vol5-sec1-401a4-2.pdf','CFR2012'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2012-title26-vol5/pdf/CFR-2012-title26-vol5-sec1-401a4-2.pdf"><span>26 CFR 1.401(a)(4)-2 - Nondiscrimination in amount of employer contributions under a defined contribution plan.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2012&page.go=Go">Code of Federal Regulations, 2012 CFR</a></p> <p></p> <p>2012-04-01</p> <p>... greater of the allocations under two or more formulas, one of which is a top-heavy formula, the top-heavy... is the greater of the allocations under two or more formulas, and one or more of those formulas is... provide uniform allocations are permitted to satisfy this requirement by meeting one of the safe harbors...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/AD1031871','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/AD1031871"><span>The Effect of Multispectral Image Fusion Enhancement on Human Efficiency</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2017-03-20</p> <p>performance of the ideal observer is indicative of the relative amount of informa- tion across various experimental manipulations. In our experimental design ...registration and fusion processes, and contributed strongly to the statistical analyses. LMB contributed to the experimental design and writing structure. All... designed to be innovative, low-cost, and (relatively) easy-to-implement, and to provide support across the spectrum of possible users including</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-02-14/pdf/2011-3231.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-02-14/pdf/2011-3231.pdf"><span>76 FR 8368 - Price Index Adjustments for Contribution and Expenditure Limits and Lobbyist Bundling Disclosure...</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-02-14</p> <p>...As mandated by provisions of the Federal Election Campaign Act of 1971, as amended (``FECA'' or ``the Act''), the Federal Election Commission (``FEC'' or ``the Commission'') is adjusting certain contribution and expenditure limits and the lobbyist bundling disclosure threshold set forth in the Act, to index the amounts for inflation. Additional details appear in the supplemental information that follows.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2013-02-06/pdf/2013-02520.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2013-02-06/pdf/2013-02520.pdf"><span>78 FR 8530 - Price Index Adjustments for Contribution and Expenditure Limitations and Lobbyist Bundling...</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2013-02-06</p> <p>...As mandated by provisions of the Federal Election Campaign Act of 1971, as amended (``FECA'' or ``the Act''), the Federal Election Commission (``FEC'' or ``the Commission'') is adjusting certain contribution and expenditure limitations and the lobbyist bundling disclosure threshold set forth in the Act, to index the amounts for inflation. Additional details appear in the supplemental information that follows.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5331584','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5331584"><span>Whole Grains Contribute Only a Small Proportion of Dietary Fiber to the U.S. Diet</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kranz, Sibylle; Dodd, Kevin W.; Juan, Wen Yen; Johnson, LuAnn K.; Jahns, Lisa</p> <p>2017-01-01</p> <p>Dietary fiber (DF), found in whole fruits, vegetables, and whole grains (WG), is considered a nutrient of concern in the US diet and increased consumption is recommended. The present study was designed to highlight this critical importance of the difference between WG, high-fiber WG, and sources of fiber that are not from WG. The study is based on the two-day diets reported consumed by the nationally representative sample of Americans participating in What We Eat In America, the dietary component of the National Health and Nutrition Examination Survey from 2003–2010. Foods consumed were classified into tertiles of DF and WG and the contribution of fiber by differing levels of WG content were examined. Foods containing high amounts of WG and DF only contributed about 7% of total fiber intake. Overall, grain-based foods contributed 54.5% of all DF consumed. Approximately 39% of DF came from grain foods that contained no WG, rather these foods contained refined grains, which contain only small amounts of DF but are consumed in large quantities. All WG-containing foods combined contributed a total of 15.3% of DF in the American diet. Thus, public health messaging needs to be changed to specifically encourage consumption of WG foods with high levels of DF to address both recommendations. PMID:28218657</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://cfpub.epa.gov/si/si_public_record_report.cfm?direntryid=335546&keyword=air&subject=air%20research&showcriteria=2&fed_org_id=111&datebeginpublishedpresented=03/01/2012&dateendpublishedpresented=03/01/2017&sortby=pubdateyear','PESTICIDES'); return false;" href="https://cfpub.epa.gov/si/si_public_record_report.cfm?direntryid=335546&keyword=air&subject=air%20research&showcriteria=2&fed_org_id=111&datebeginpublishedpresented=03/01/2012&dateendpublishedpresented=03/01/2017&sortby=pubdateyear"><span>Pathways of inhalation exposure to manganese in children ...</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.epa.gov/pesticides/search.htm">EPA Pesticide Factsheets</a></p> <p></p> <p></p> <p>Manganese (Mn) is both essential element and neurotoxicant. Exposure to Mn can occur from various sources and routes. Structural equation modeling was used to examine routes of exposure to Mn among children residing near a ferromanganese refinery in Marietta, Ohio. An inhalation pathway model to ambient air Mn was hypothesized. Data for model evaluation were obtained from participants in the Communities Actively Researching Exposure Study (CARES). These data were collected in 2009 and included levels of Mn in residential soil and dust, levels of Mn in children's hair, information on the amount of time the child spent outside, heat and air conditioning in the home and level of parent education. Hair Mn concentration was the primary endogenous variable used to assess the theoretical inhalation exposure pathways. The model indicated that household dust Mn was a significant contributor to child hair Mn (0.37). Annual ambient air Mn concentration (0.26), time children spent outside (0.24) and soil Mn (0.24) significantly contributed to the amount of Mn in household dust. These results provide a potential framework for understanding the inhalation exposure pathway for children exposed to ambient air Mn who live in proximity to an industrial emission source. The purpose of this study was to use a structural equations modeling approach combined with exposure estimates derived from air-dispersion modeling to assess potential inhalation exposure pathways for children to a</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22114427','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22114427"><span>Apical extrusion of debris and irrigants using hand and three rotary instrumentation systems − An in vitro study.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Madhusudhana, Koppolu; Mathew, Vinod Babu; Reddy, Nelaturi Madhusudhan</p> <p>2010-10-01</p> <p>Sterilization of the root canal is a prime aim of successful endodontics. The cleaning and shaping of the canal is directed as achieving this goal. The extrusion of apical debris has a deleterious effect on the prognosis of root canal treatment. Several instrument designs and instrumentation techniques have been developed to prevent this. Forty caries free single rooted human mandibular premolar teeth were divided in four groups of ten teeth each. Teeth in each group were instrumented until the working length with rotary ProTaper, K3, Mtwo systems, and hand K-type stainless steel files. Debris and irrigant extruded from the apical foramen were collected into vials and the amounts were quantitatively determined. The data obtained were analyzed using Kruskal-Wallis one-way analysis of variance and Mann-Whitney U tests. The results show that all instrumentation techniques produced significant amount of extruded debris and irrigant. The engine-driven nickel-titanium systems showed less apical extrusion of debris and irrigant than manual technique. No statistically significant difference was found between the groups at [P > 0.05]. Maximum apical debris and irrigant extrusion was seen with K-file group and least in the Mtwo group. The use of rotary files and techniques to perform instrumentation does show less extrusion of the debris and irrigant from the apex. This can contribute to more successful endodontic therapy.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28950987','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28950987"><span>Cervical cancer cells suppress effector functions of cytotoxic T cells through the adenosinergic pathway.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mora-García, M L; Ávila-Ibarra, L R; García-Rocha, R; Weiss-Steider, B; Hernández-Montes, J; Don-López, C A; Gutiérrez-Serrano, V; Titla-Vilchis, I J; Fuentes-Castañeda, M C; Monroy-Mora, A; Jave-Suárez, L F; Chacón-Salinas, R; Vallejo-Castillo, L; Pérez-Tapia, S M; Monroy-García, A</p> <p>2017-10-01</p> <p>The expression of CD73 in tumor cells plays a significant role in the production of adenosine (Ado) that suppresses antitumor effector cells. In this study we analyzed the capability of HPV-positive (HPV+) cervical cancer (CeCa) cell lines CaSki, SiHa, HeLa, and RoVa; and HPV-negative (HPV-) cell lines C33A and ViBo to produce Ado and inhibit effector functions of CD8+ T cells. HPV+ CeCa cells expressed significantly higher levels of CD73 in the membrane (p<0.01) than HPV- CeCa cells and this expression was associated with the production of larger amounts of Ado (>400μM) compared to HPV-CeCa cells (<200μM) in the presence of AMP, as well asa stronger inhibition of (>50%) proliferation, activation, and cytotoxic activity of CD8+ T cells via interaction with A2A adenosine receptor. We also provide evidence that silenced E6/E7 expression in CeCa cells, strongly reduced its CD73 expression level and its capability to generate Ado. This results suggest that HPV infection, which is associated with more than 99% of CeCa cases, may present an increased constitutive expression of CD73 in cervical neoplasia to contribute to the suppression of the immune response mediated by the production of large amounts of Ado. Copyright © 2017 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28005141','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28005141"><span>Case-related factors affecting cutting errors of the proximal tibia in total knee arthroplasty assessed by computer navigation.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tsukeoka, Tadashi; Tsuneizumi, Yoshikazu; Yoshino, Kensuke; Suzuki, Mashiko</p> <p>2018-05-01</p> <p>The aim of this study was to determine factors that contribute to bone cutting errors of conventional instrumentation for tibial resection in total knee arthroplasty (TKA) as assessed by an image-free navigation system. The hypothesis is that preoperative varus alignment is a significant contributory factor to tibial bone cutting errors. This was a prospective study of a consecutive series of 72 TKAs. The amount of the tibial first-cut errors with reference to the planned cutting plane in both coronal and sagittal planes was measured by an image-free computer navigation system. Multiple regression models were developed with the amount of tibial cutting error in the coronal and sagittal planes as dependent variables and sex, age, disease, height, body mass index, preoperative alignment, patellar height (Insall-Salvati ratio) and preoperative flexion angle as independent variables. Multiple regression analysis showed that sex (male gender) (R = 0.25 p = 0.047) and preoperative varus alignment (R = 0.42, p = 0.001) were positively associated with varus tibial cutting errors in the coronal plane. In the sagittal plane, none of the independent variables was significant. When performing TKA in varus deformity, careful confirmation of the bone cutting surface should be performed to avoid varus alignment. The results of this study suggest technical considerations that can help a surgeon achieve more accurate component placement. IV.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3204380','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3204380"><span>Serum Amylase in Bulimia Nervosa and Purging Disorder: Differentiating the Association with Binge Eating versus Purging Behavior</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Wolfe, Barbara E.; Jimerson, David C.; Smith, Adrian; Keel, Pamela K.</p> <p>2011-01-01</p> <p>Objective Elevated serum amylase levels in bulimia nervosa (BN), associated with increased salivary gland size and self-induced vomiting in some patients, provide a possible marker of symptom severity. The goal of this study was to assess whether serum hyperamylasemia in BN is more closely associated with binge eating episodes involving consumption of large amounts of food or with purging behavior. Method Participants included women with BN (n=26); women with “purging disorder” (PD), a subtype of EDNOS characterized by recurrent purging in the absence of objectively large binge eating episodes (n=14); and healthy non-eating disorder female controls (n=32). There were no significant differences in age or body mass index (BMI) across groups. The clinical groups reported similar frequency of self-induced vomiting behavior and were free of psychotropic medications. Serum samples were obtained after overnight fast and were assayed for alpha-amylase by enzymatic method. Results Serum amylase levels were significantly elevated in BN (60.7 ± 25.4 international units [IU]/liter, mean ± sd) in comparison to PD (44.7 ± 17.1 IU/L, p < 02) and to Controls (49.3 ± 15.8, p < .05). Conclusion These findings provide evidence to suggest that it is recurrent binge eating involving large amounts of food, rather than self-induced vomiting, which contributes to elevated serum amylase values in BN. PMID:21781981</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_25 --> <div class="footer-extlink text-muted" style="margin-bottom:1rem; text-align:center;">Some links on this page may take you to non-federal websites. 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