Sample records for control future studies

  1. The dampening effect of employees' future orientation on cyberloafing behaviors: the mediating role of self-control.

    PubMed

    Zhang, Heyun; Zhao, Huanhuan; Liu, Jingxuan; Xu, Yan; Lu, Hui

    2015-01-01

    Previous studies on reducing employees' cyberloafing behaviors have primarily examined the external control factors but seldomly taken individual internal subjective factors into consideration. Future orientation, an important individual factor, is defined as the extent to which one plans for future time and considers future consequences of one's current behavior. To explore further whether and how employees' future orientation can dampen their cyberloafing behaviors, two studies were conducted to examine the relationship between employees' future orientation and cyberloafing behaviors. The mediation effect of employees' objective and subjective self-control between them was also examined. In Study 1, a set of questionnaires was completed, and the results revealed that the relationship between employees' future orientation and cyberloafing behaviors was negative, and objective self-control mediated the relationship. Next, we conducted a priming experiment (Study 2) to examine the causal relationship and psychological mechanism between employees' future orientation and cyberloafing behaviors. The results demonstrated that employees' future-orientation dampened their attitudes and intentions to engage in cyberloafing, and subjective self-control mediated this dampening effect. Theoretical and practical implications of these findings are also discussed.

  2. The dampening effect of employees’ future orientation on cyberloafing behaviors: the mediating role of self-control

    PubMed Central

    Zhang, Heyun; Zhao, Huanhuan; Liu, Jingxuan; Xu, Yan; Lu, Hui

    2015-01-01

    Previous studies on reducing employees’ cyberloafing behaviors have primarily examined the external control factors but seldomly taken individual internal subjective factors into consideration. Future orientation, an important individual factor, is defined as the extent to which one plans for future time and considers future consequences of one’s current behavior. To explore further whether and how employees’ future orientation can dampen their cyberloafing behaviors, two studies were conducted to examine the relationship between employees’ future orientation and cyberloafing behaviors. The mediation effect of employees’ objective and subjective self-control between them was also examined. In Study 1, a set of questionnaires was completed, and the results revealed that the relationship between employees’ future orientation and cyberloafing behaviors was negative, and objective self-control mediated the relationship. Next, we conducted a priming experiment (Study 2) to examine the causal relationship and psychological mechanism between employees’ future orientation and cyberloafing behaviors. The results demonstrated that employees’ future-orientation dampened their attitudes and intentions to engage in cyberloafing, and subjective self-control mediated this dampening effect. Theoretical and practical implications of these findings are also discussed. PMID:26483735

  3. The relationship between trait self-control, consideration for future consequence and organizational citizenship behavior among Chinese employees.

    PubMed

    Wang, Yu-Jie; Dou, Kai; Tang, Zhi-Wen

    2017-01-01

    Organizational citizenship behavior (OCB) is important to the development of an organization. Research into factors that foster OCB and the underlying processes are therefore substantially crucial. The current study aimed to test the association between trait self-control and OCB and the mediating role of consideration for future consequence. Four hundred and ninety-four Chinese employees (275 men, 219 women) took part in the study. Participants completed a battery of self-report measures online that assessed trait self-control, tendencies of consideration of future consequence, and organizational citizenship behavior. Path analysis was conducted and bootstrapping technique (N = 5000), a resampling method that is asymptotically more accurate than the standard intervals using sample variance and assumptions of normality, was used to judge the significance of the mediation. Results of path analysis showed that trait self-control was positively related to OCB. More importantly, the "trait self-control-OCB" link was mediated by consideration of future consequence-future, but not by consideration of future consequence-immediate. Employees with high trait self-control engage in more organizational citizenship behavior and this link can be partly explained by consideration of future consequence-future.

  4. Feeling Closer to the Future Self and Doing Better: Temporal Psychological Mechanisms Underlying Academic Performance.

    PubMed

    Adelman, Robert Mark; Herrmann, Sarah D; Bodford, Jessica E; Barbour, Joseph E; Graudejus, Oliver; Okun, Morris A; Kwan, Virginia S Y

    2017-06-01

    This research examined the function of future self-continuity and its potential downstream consequences for academic performance through relations with other temporal psychological factors and self-control. We also addressed the influence of cultural factors by testing whether these relations differed by college generation status. Undergraduate students enrolled at a large public university participated in two studies (Study 1: N = 119, M age  = 20.55, 56.4% women; Study 2: N = 403, M age  = 19.83, 58.3% women) in which they completed measures of temporal psychological factors and psychological resources. In Study 2, we also obtained academic records to link responses to academic performance. Future self-continuity predicted subsequent academic performance and was related positively to future focus, negatively to present focus, and positively to self-control. Additionally, the relation between future focus and self-control was stronger for continuing-generation college students than first-generation college students. Future self-continuity plays a pivotal role in academic contexts. Findings suggest that it may have positive downstream consequences on academic achievement by directing attention away from the present and toward the future, which promotes self-control. Further, the strategy of focusing on the future may be effective in promoting self-control only for certain cultural groups. © 2016 Wiley Periodicals, Inc.

  5. Improving prospective memory performance with future event simulation in traumatic brain injury patients.

    PubMed

    Mioni, Giovanna; Bertucci, Erica; Rosato, Antonella; Terrett, Gill; Rendell, Peter G; Zamuner, Massimo; Stablum, Franca

    2017-06-01

    Previous studies have shown that traumatic brain injury (TBI) patients have difficulties with prospective memory (PM). Considering that PM is closely linked to independent living it is of primary interest to develop strategies that can improve PM performance in TBI patients. This study employed Virtual Week task as a measure of PM, and we included future event simulation to boost PM performance. Study 1 evaluated the efficacy of the strategy and investigated possible practice effects. Twenty-four healthy participants performed Virtual Week in a no strategy condition, and 24 healthy participants performed it in a mixed condition (no strategy - future event simulation). In Study 2, 18 TBI patients completed the mixed condition of Virtual Week and were compared with the 24 healthy controls who undertook the mixed condition of Virtual Week in Study 1. All participants also completed a neuropsychological evaluation to characterize the groups on level of cognitive functioning. Study 1 showed that participants in the future event simulation condition outperformed participants in the no strategy condition, and these results were not attributable to practice effects. Results of Study 2 showed that TBI patients performed PM tasks less accurately than controls, but that future event simulation can substantially reduce TBI-related deficits in PM performance. The future event simulation strategy also improved the controls' PM performance. These studies showed the value of future event simulation strategy in improving PM performance in healthy participants as well as in TBI patients. TBI patients performed PM tasks less accurately than controls, confirming prospective memory impairment in these patients. Participants in the future event simulation condition out-performed participants in the no strategy condition. Future event simulation can substantially reduce TBI-related deficits in PM performance. Future event simulation strategy also improved the controls' PM performance. © 2017 The British Psychological Society.

  6. Hopelessness and future thinking in parasuicide: the role of perfectionism.

    PubMed

    Hunter, Elizabeth C; O'Connor, Rory C

    2003-11-01

    This study had three aims: (1) to independently replicate the future thinking effect, that parasuicides, when compared with controls, show a deficit in positive future thinking but no increase in negative future thinking; (2) to determine whether positive future thinking and socially prescribed perfectionism discriminate general hospital parasuicides from controls beyond measures of affect and; (3) to explore the relationship between future thinking and perfectionism. A cross-sectional design was employed. Three groups of participants took part: hospital parasuicide patients (N=22), hospital controls (N=22) and community controls (N=21). Parasuicide patients admitted, via accident and emergency, to a general hospital were matched with hospital and community controls and assessed on measures of hopelessness, depression, anxiety, perfectionism, and future thinking. There was evidence to support the future thinking effect. A discriminant function analysis revealed that social perfectionism and positive future thinking did indeed discriminate parasuicides from controls beyond the effects of hopelessness, depression, and anxiety. Exploratory relationships between perfectionism and positive future thinking were also reported. The results reinforce the importance of future thinking in parasuicide. Moreover, the role of social perfectionism in the suicidal process was elucidated and ought to be replicated within a prospective design.

  7. Schizophrenia Spectrum Disorders Show Reduced Specificity and Less Positive Events in Mental Time Travel

    PubMed Central

    Chen, Xing-jie; Liu, Lu-lu; Cui, Ji-fang; Wang, Ya; Chen, An-tao; Li, Feng-hua; Wang, Wei-hong; Zheng, Han-feng; Gan, Ming-yuan; Li, Chun-qiu; Shum, David H. K.; Chan, Raymond C. K.

    2016-01-01

    Mental time travel refers to the ability to recall past events and to imagine possible future events. Schizophrenia (SCZ) patients have problems in remembering specific personal experiences in the past and imagining what will happen in the future. This study aimed to examine episodic past and future thinking in SCZ spectrum disorders including SCZ patients and individuals with schizotypal personality disorder (SPD) proneness who are at risk for developing SCZ. Thirty-two SCZ patients, 30 SPD proneness individuals, and 33 healthy controls participated in the study. The Sentence Completion for Events from the Past Test (SCEPT) and the Sentence Completion for Events in the Future Test were used to measure past and future thinking abilities. Results showed that SCZ patients showed significantly reduced specificity in recalling past and imagining future events, they generated less proportion of specific and extended events compared to healthy controls. SPD proneness individuals only generated less extended events compared to healthy controls. The reduced specificity was mainly manifested in imagining future events. Both SCZ patients and SPD proneness individuals generated less positive events than controls. These results suggest that mental time travel impairments in SCZ spectrum disorders and have implications for understanding their cognitive and emotional deficits. PMID:27507958

  8. Phenomenological Characteristics of Future Thinking in Alzheimer's Disease.

    PubMed

    Moustafa, Ahmed A; El Haj, Mohamad

    2018-05-11

    This study investigates phenomenological reliving of future thinking in Alzheimer's disease (AD) patients and matched controls. All participants were asked to imagine in detail a future event, and afterward, were asked to rate phenomenological characteristics of their future thinking. As compared to controls, AD participants showed poor rating for reliving, travel in time, visual imagery, auditory imagery, language, and spatiotemporal specificity. However, no significant differences were observed between both groups in emotion and importance of future thinking. Results also showed lower rating for visual imagery relative to remaining phenomenological features in AD participants compared to controls; conversely, these participants showed higher ratings for emotion and importance of future thinking. AD seems to compromise some phenomenological characteristics of future thinking, especially, visual imagery; however, other phenomenological characteristics, such as emotion, seem to be relatively preserved in these populations. By highlighting the phenomenological experience of future thinking in AD, our paper opens a unique window into the conscious experience of the future in AD patients.

  9. Self-control and Task Timing Shift Self-efficacy and Influence Willingness to Engage in Effortful Tasks

    PubMed Central

    Ein-Gar, Danit; Steinhart, Yael

    2017-01-01

    Self-efficacy constitutes a key factor that influences people's inclination to engage in effortful tasks. In this study, we focus on an interesting interplay between two prominent factors known to influence engagement in effortful tasks: the timing of the task (i.e., whether the task is scheduled to take place in the near or distant future) and individuals' levels of self-control. Across three studies, we show that these two factors have an interacting effect on self-efficacy. Low self-control (LSC) individuals report higher self-efficacy for distant-future effortful tasks than for near-future tasks, whereas high self-control (HSC) individuals report higher self-efficacy for near-future tasks than for distant future tasks. We further demonstrate how self-efficacy then molds individuals' willingness to engage in those effortful tasks. Given that a particular task may comprise effortful aspects alongside more enjoyable aspects, we show that the effects we observe emerge with regard to a task whose effortful aspects are salient and that the effects are eliminated when the enjoyable aspects of that same task are highlighted. PMID:29075225

  10. Study on the Future Internet System through Analysis of SCADA Systems

    NASA Astrophysics Data System (ADS)

    Song, Jae-Gu; Jung, Sungmo; Kim, Seoksoo

    Research on the future Internet is focused on establishing standards by solving problems through various projects and accepting various requirements. In this study, the SCADA (Supervisory Control And Data Acquisition) environment, closely related with national infrastructure, is analyzed in order to explore requirements of the future Internet and then those of the SCADA network. Also, this study provides SCADA system environments for the future Internet.

  11. The effects of violence exposure on the development of impulse control and future orientation across adolescence and early adulthood: Time-specific and generalized effects in a sample of juvenile offenders.

    PubMed

    Monahan, Kathryn C; King, Kevin M; Shulman, Elizabeth P; Cauffman, Elizabeth; Chassin, Laurie

    2015-11-01

    Impulse control and future orientation increase across adolescence, but little is known about how contextual factors shape the development of these capacities. The present study investigates how stress exposure, operationalized as exposure to violence, alters the developmental pattern of impulse control and future orientation across adolescence and early adulthood. In a sample of 1,354 serious juvenile offenders, higher exposure to violence was associated with lower levels of future orientation at age 15 and suppressed development of future orientation from ages 15 to 25. Increases in witnessing violence or victimization were linked to declines in impulse control 1 year later, but only during adolescence. Thus, beyond previous experiences of exposure to violence, witnessing violence and victimization during adolescence conveys unique risk for suppressed development of self-regulation.

  12. Explaining why larks are future-oriented and owls are present-oriented: self-control mediates the chronotype-time perspective relationships.

    PubMed

    Milfont, Taciano L; Schwarzenthal, Miriam

    2014-05-01

    Recent studies provide evidence for the chronotype-time perspective relationships. Larks are more future-oriented and owls are more present-oriented. The present study expands this initial research by examining whether the associations are replicable with other time perspective measures, and whether self-control explains the observed relationships. Chronotype was assessed with the Morningness-Eveningness Questionnaire and the basic associations with the Zimbardo Time Perspective Inventory were replicated in a sample of 142 New Zealand students, but not with other measures. Self-control mediated the influence of morningness on both future time perspective and delay of gratification. Implications of the findings are discussed.

  13. Positive future orientation as a mediator between traumatic events and mental health among children affected by HIV/AIDS in rural China.

    PubMed

    Zhang, Jintao; Zhao, Guoxiang; Li, Xiaoming; Hong, Yan; Fang, Xiaoyi; Barnett, Douglas; Lin, Xiuyun; Zhao, Junfeng; Zhang, Liying

    2009-12-01

    The current study was designed to explore the effect of future orientation in mediating the relationship between traumatic events and mental health in children affected by HIV/AIDS in rural China. Cross-sectional data were collected from 1221 children affected by HIV/AIDS (755 AIDS orphans and 466 vulnerable children). Future orientation among children was measured using three indicators (future expectation, hopefulness toward the future, and perceived control over the future). Measures of mental health consisted of depression, loneliness, and self-esteem. Children's experience of any traumatic events was measured using a modified version of the Life Incidence of Traumatic Events-Student Form. Mediation analysis was conducted using structural equation modeling (SEM) methods. Among the children surveyed, most of the traumatic indicators were negatively associated with future expectation, hopefulness, perceived control, and self-esteem, and positively associated with depression and loneliness. The SEM of mediation analysis demonstrated an adequate fit. Future orientation fully mediated the relationship between traumatic events and mental health and accounted for 67.9% of the total effect of traumatic events on mental health. Results of this study support the positive effect of future expectation in mediating the relationship between traumatic events and mental health among children affected by HIV/AIDS in China. Future mental health promotion and intervention efforts targeting children affected by HIV/AIDS should include components that can mitigate the negative impact of traumatic events on their lives. These components may aim to develop children's positive future expectations, increase their hopefulness toward the future, and improve their perceived control over the future.

  14. Report of Study On Airlines' Anticipated Near Future Cockpit Control and Display Capabilities and Plans For Data Link Communication, Part 2

    DOT National Transportation Integrated Search

    1995-07-01

    In support of the Federal Aviation Administration (FAA) Airborne Data Link : Program, CTA INCORPORATED researched airlines' anticipated near future cockpit : control and display capabilities and associated plans for Data Link : communication. This ef...

  15. Future-directed thinking in first-episode psychosis.

    PubMed

    Goodby, Emmeline; MacLeod, Andrew K

    2016-06-01

    This study employed the Future Thinking Task (MacLeod et al., 2005, Br. J. Clin. Psychol., 44, 495) to investigate whether future-directed thinking in first-episode psychosis is significantly different from that of matched controls, and to identify its correlates in this patient group. Cross-sectional, mixed-model, case-control design. Participants were 30 patients with first-episode psychosis and 27 matched controls. The Future Thinking Task was used to assess future-directed thinking in both groups. Anxiety and depression were also measured as well as self-report measures of hopelessness, suicide ideation and a measure of negative symptoms. Individuals with psychosis were impaired in future-directed thinking in both positive and negative domains, particularly with respect to the coming year. Increased self-reported hopelessness was associated with reduced positive future thinking and increased negative future thinking. Increased positive future thinking was also associated with reduced severity of negative symptoms, whilst negative future thinking was associated with suicide ideation. Individuals with first-episode psychosis show a reduction in positive future thinking in line with that seen in other clinical groups, but this is accompanied by an unexpected reduction in negative future thinking. The findings suggest a general disengagement with the future in this group that may affect recovery and functioning. Individuals with first-episode psychosis may benefit from interventions to help them engage with their future, in particular in the mid-range, up to 1 year. The Future Thinking Task may be a helpful addition to the assessment of suicide risk in those with first-episode psychosis. Decreased positive future thinking was associated with increased severity of negative symptoms, indicating a potential new treatment angle for this resistant aspect of psychosis. The cross-sectional design of this study does not allow for conclusions about the causal relationship between psychosis and future-directed thinking. This study investigated future-directed thinking in individuals with a range of psychotic illnesses employing a trans-diagnostic approach; therefore, conclusions cannot be drawn about the nature of future-directed thinking in individual psychotic disorders. © 2015 The British Psychological Society.

  16. Future Time Perspective, Socio-Emotional Regulation, and Diurnal Cortisol Patterns in Post-Secondary Engineering Students

    ERIC Educational Resources Information Center

    Cheng, Katherine C.

    2017-01-01

    Built upon Control Value Theory, this dissertation consists of two studies that examine university students' future-oriented motivation, socio-emotional regulation, and diurnal cortisol patterns in understanding students' well-being in the academic-context. Study 1 examined the roles that Learning-related Hopelessness and Future Time Perspective…

  17. Prediagnostic serum levels of inflammatory biomarkers are correlated with future development of lung and esophageal cancer

    PubMed Central

    Keeley, Brieze R; Islami, Farhad; Pourshams, Akram; Poustchi, Hossein; Pak, Jamie S; Brennan, Paul; Khademi, Hooman; Genden, Eric M; Abnet, Christian C; Dawsey, Sanford M; Boffetta, Paolo; Malekzadeh, Reza; Sikora, Andrew G

    2014-01-01

    This study tests the hypothesis that prediagnostic serum levels of 20 cancer-associated inflammatory biomarkers correlate directly with future development of head and neck, esophageal, and lung cancers in a high-risk prospective cohort. This is a nested case–control pilot study of subjects enrolled in the Golestan Cohort Study, an ongoing epidemiologic project assessing cancer trends in Golestan, Iran. We measured a panel of 20 21cytokines, chemokines, and inflammatory molecules using Luminex technology in serum samples collected 2 or more years before cancer diagnosis in 78 aerodigestive cancer cases and 81 controls. Data was analyzed using Wilcoxon rank sum test, odds ratios, receiver operating characteristic areas of discrimination, and multivariate analysis. Biomarkers were profoundly and globally elevated in future esophageal and lung cancer patients compared to controls. Odds ratios were significant for association between several biomarkers and future development of esophageal cancer, including interleukin-1Rα (IL-1Ra; 35.9), interferon α2 (IFN-a2; 34.0), fibroblast growth factor-2 (FGF-2; 17.4), and granulocyte/macrophage colony-stimulating factor (GM-CSF; 17.4). The same pattern was observed among future lung cancer cases for G-CSF (27.7), GM-CSF (13.3), and tumor necrosis factor-α (TNF-a; 8.6). By contrast, the majority of biomarkers studied showed no significant correlation with future head and neck cancer development. This study provides the first direct evidence that multiple inflammatory biomarkers are coordinately elevated in future lung and esophageal cancer patients 2 or more years before cancer diagnosis. PMID:25040886

  18. How adolescents construct their future: the effect of loneliness on future orientation.

    PubMed

    Seginer, Rachel; Lilach, Efrat

    2004-12-01

    This study examined the effect of loneliness, gender, and two dimensions of prospective life domains on adolescent future orientation. Future orientation was studied in four prospective domains: social relations, marriage and family, higher education and work and career. These domains are described in terms of two dimensions: theme (relational vs. instrumental) and distance (near vs. distant future). Data collected from Israeli Jewish adolescents (11th graders) were analysed by repeated measures ANOVAs and ANCOVAs (covariate: depressive experiences) for seven future orientation variables: value, expectance, control (motivational variables), hopes, fears (cognitive representation variables), exploration, commitment (behavioural variables). As predicted, lonely adolescents scored lower than socially embedded adolescents on future orientation variables applied to the relational and near future domains and lonely boys scored lower than lonely girls. However, effects were found only on the three future orientation motivational variables and not on the cognitive representation and behavioural variables. Contrary to prediction controlling for the effect of depressive experiences did not reduce the effect of loneliness on the future orientation variables, but reduced the tendency of adolescents to score higher on all future orientation variables in the instrumental than in the relational prospective domains. The contribution of these findings to the understanding of adolescent loneliness and future orientation was discussed and directions for future research were suggested.

  19. Study of the Application of Separation Control by Unsteady Excitation to Civil Transport Aircraft

    NASA Technical Reports Server (NTRS)

    McLean, J. D.; Crouch, J. D.; Stoner, R. C.; Sakurai, S.; Seidel, G. E.; Feifel, W. M.; Rush, H. M.

    1999-01-01

    This study provides a preliminary assessment of the potential benefits of applying unsteady separation control to transport aircraft. Estimates are given for some of the costs associated with a specific application to high-lift systems. High-leverage areas for future research were identified during the course of the study. The study was conducted in three phases. Phase 1 consisted of a coarse screening of potential applications within the aerodynamics discipline. Potential benefits were identified and in some cases quantified in a preliminary way. Phase 2 concentrated on the application to the wing high-lift system, deemed to have the greatest potential benefit for commercial transports. A team of experts, including other disciplines (i.e. hydraulic, mechanical, and electrical systems, structures, configurations, manufacturing, and finance), assessed the feasibility, benefits, and costs to arrive at estimates of net benefits. In both phases of the study, areas of concern and areas for future research were identified. In phase 3 of this study, the high-leverage areas for future research were prioritized as a guide for future efforts aimed at the application of active flow control to commercial transport aircraft.

  20. Parenting and Adolescents' Depressive Symptoms: The Mediating Role of Future Time Perspective.

    PubMed

    Diaconu-Gherasim, Loredana R; Bucci, Colleen M; Giuseppone, Kathryn R; Brumariu, Laura E

    2017-10-03

    This study investigated the relations between maternal and paternal rearing practices and adolescents' depressive symptoms, and whether time perspective in adolescence explains these links. The sample included 306 students (158 girls), aged between 10.83 and 14.42 years. Adolescents completed questionnaires assessing their perceptions of maternal and paternal acceptance and psychological control, and of their future time perspective and depressive symptoms. Adolescents who rated their mothers as more accepting and those who rated their fathers as less psychologically controlling also reported lower levels of depressive symptoms and greater future time perspective. Further, adolescents who had greater future time perspective reported lower levels of depressive symptoms. Finally, time perspective partially mediated the relations of maternal and paternal acceptance, and paternal control with depressive symptoms in adolescence. The findings highlight the unique relations of maternal acceptance and paternal psychological control with adolescents' depressive symptoms, and that future time perspective is one mechanism that might explain why parenting strategies are linked with depressive symptoms in adolescence.

  1. The relationship between parenting and the economic orientation and behavior of Norwegian adolescents.

    PubMed

    Nyhus, Ellen K; Webley, Paul

    2013-01-01

    Little is known about the economic socialization of children and adolescents and the role of parents in this process. The authors' purpose was to explore the role of parenting in the intergenerational transfer of economic orientation and economic behavior. More specifically, they studied the link between four parenting dimensions (parental warmth-responsiveness, behavioral control, psychological control, autonomy granting), three parenting styles (authoritative, authoritarian, and neglectful) and adolescents' conscientiousness, future time perspective, and present hedonistic orientation. The authors also studied the relationships between these dispositions and the adolescents' spending preferences and ability to control spending. They used data collected from 14-16-year-olds (n = 597) and their parents (n = 469) in Norway. Results showed that adolescents who perceived their parents as psychologically controlling were less future oriented and conscientious, and were more present hedonistic oriented than others, while adolescents who perceived their parents as responsive, autonomy granting, and controlling of behavior were more future orientated and conscientious than others. Adolescents' scores for conscientiousness and future orientation were negatively associated with preferences for spending and positively with the ability to control spending, while the opposite relationships were found with respect to a present hedonistic orientation. Parental style was also found to be important for the future educational plans of adolescents, and plans for higher education were more frequent among adolescents who characterized their parents as authoritative than among those who perceived their parents as neglectful. Implications of the findings for economic socialization are discussed.

  2. Self-control mediates the relationship between time perspective and BMI.

    PubMed

    Price, Menna; Higgs, Suzanne; Lee, Michelle

    2017-01-01

    Trait future time perspective measures the extent to which behaviour is dominated by a striving for future goals and rewards. Trait present time perspective measures orientation towards immediate pleasure. Previous research has explored the relationship between future and present time perspective and BMI with mixed findings. In addition, the psychological mechanism underlying this relationship is unclear. Self-control is a likely candidate, as it has been related to both BMI and time perspective, but the relationship between all of these concepts has not been examined in a single study. Therefore, the aim of this study was to examine if trait self-control mediates the relationship between time perspective (future and present) and BMI. Self-report time perspective (ZTPI), self-control (SCS) and height/weight data were collected using an online survey from a mixed student and community sample (N = 218) with wide ranging age (mean 29, SD 11, range 18-73 years) and BMI (mean 24, SD 4, range 15-43). The results of a structural equation model including both facets of time perspective suggested that the traits are related yet distinct measures that independently predict BMI through changes in self-control. Bootstrap mediation analysis showed that self-control mediated the relationship between both future time perspective (95% CI, -0.10 to -0.02) and present time perspective (95% CI, 0.03 to 0.17), and BMI in opposite directions. Participants with higher future time perspective scores (higher present time perspective scores) had higher (lower) self-control, which predicted lower (higher) BMI. These results are consistent with previous research suggesting an important role for time perspective in health outcomes. Self-control likely mediates the relationship between temporal perspectives and BMI, suggesting that time perspective may be a target for individualised interventions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. [The case-case-time-control study design].

    PubMed

    Wang, Jing; Zhuo, Lin; Zhan, Siyan

    2014-12-01

    Although the 'self-matched case-only studies' (such as the case-cross-over or self-controlled case-series method) can control the time-invariant confounders (measured or unmeasured) through design of the study, however, they can not control those confounders that vary with time. A bidirectional case-crossover design can be used to adjust the exposure-time trends. In the areas of pharmaco-epidemiology, illness often influence the future use of medications, making a bidirectional study design problematic. Suissa's case-time-control design combines the case-crossover and the case-control design which could adjust for exposure-trend bias, but the control group may reintroduce selection bias, if the matching does not go well. We propose a "case-case-time-control" design which is an extension of the case-time-control design. However, rather than using a sample of external controls, we choose those future cases as controls for current cases to counter the bias that arising from temporal trends caused by exposure to the target of interest. In the end of this article we will discuss the strength and limitations of this design based on an applied example.

  4. Control technology for future aircraft propulsion systems

    NASA Technical Reports Server (NTRS)

    Zeller, J. R.; Szuch, J. R.; Merrill, W. C.; Lehtinen, B.; Soeder, J. F.

    1984-01-01

    The need for a more sophisticated engine control system is discussed. The improvements in better thrust-to-weight ratios demand the manipulation of more control inputs. New technological solutions to the engine control problem are practiced. The digital electronic engine control (DEEC) system is a step in the evolution to digital electronic engine control. Technology issues are addressed to ensure a growth in confidence in sophisticated electronic controls for aircraft turbine engines. The need of a control system architecture which permits propulsion controls to be functionally integrated with other aircraft systems is established. Areas of technology studied include: (1) control design methodology; (2) improved modeling and simulation methods; and (3) implementation technologies. Objectives, results and future thrusts are summarized.

  5. Amnesia and future thinking: Exploring the role of memory in the quantity and quality of episodic future thoughts.

    PubMed

    Cole, Scott N; Morrison, Catriona M; Barak, Ohr; Pauly-Takacs, Katalin; Conway, Martin A

    2016-06-01

    To examine the impact of memory accessibility on episodic future thinking. Single-case study of neurological patient HCM and an age-matched comparison group of neurologically Healthy Controls. We administered a full battery of tests assessing general intelligence, memory, and executive functioning. To assess autobiographical memory, the Autobiographical Memory Interview (Kopelman, Wilson, & Baddeley, 1990. The Autobiographical Memory Interview. Bury St. Edmunds, UK: Thames Valley Test Company) was administered. The Past Episodic and Future Episodic sections of Dalla Barba's Confabulation Battery (Dalla Barba, 1993, Cogn. Neuropsychol., 1, 1) and a specifically tailored Mental Time Travel Questionnaire were administered to assess future thinking in HCM and age-matched controls. HCM presented with a deficit in forming new memories (anterograde amnesia) and recalling events from before the onset of neurological impairment (retrograde amnesia). HCM's autobiographical memory impairments are characterized by a paucity of memories from Recent Life. In comparison with controls, two features of his future thoughts are apparent: Reduced episodic future thinking and outdated content of his episodic future thoughts. This article suggests neuropsychologists should look beyond popular conceptualizations of the past-future relation in amnesia via focussing on reduced future thinking. Investigating both the quantity and quality of future thoughts produced by amnesic patients may lead to developments in understanding the complex nature of future thinking disorders resulting from memory impairments. We highlight the clinical importance of examining the content of future thoughts in amnesic patients, rather than only its quantitative reduction. We propose an explanation of how quantitative and qualitative aspects of future thinking could be affected by amnesia. This could provide a useful approach to understand clinical cases of impaired prospection. Systematic group investigations are required to fully examine our hypothesis. Although the current study utilized typical future thinking measures, these may be limited and we highlight the need to develop clinically relevant measures of prospection. © 2015 The British Psychological Society.

  6. Monitoring and control requirement definition study for Dispersed Storage and Generation (DSG). Volume 4, appendix C: Identification from utility visits of present and future approaches to integration of DSG into distribution networks

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Visits to four utilities concerned with the use of DSG power sources on their distribution networks yielded useful impressions of present and future approaches to the integration of DSGs into electrical distribution network. Different approaches to future utility systems with DSG are beginning to take shape. The new DSG sources will be in decentralized locations with some measure of centralized control. The utilities have yet to establish firmly the communication and control means or their organization. For the present, the means for integrating the DSGs and their associated monitoring and control equipment into a unified system have not been decided.

  7. Episodic simulation of future events is impaired in mild Alzheimer's disease

    PubMed Central

    Addis, Donna Rose; Sacchetti, Daniel C.; Ally, Brandon A.; Budson, Andrew E.; Schacter, Daniel L.

    2009-01-01

    Recent neuroimaging studies have demonstrated that both remembering the past and simulating the future activate a core neural network including the medial temporal lobes. Regions of this network, in particular the medial temporal lobes, are prime sites for amyloid deposition and are structurally and functionally compromised in Alzheimer's disease (AD). While we know some functions of this core network, specifically episodic autobiographical memory, are impaired in AD, no study has examined whether future episodic simulation is similarly impaired. We tested the ability of sixteen AD patients and sixteen age-matched controls to generate past and future autobiographical events using an adapted version of the Autobiographical Interview. Participants also generated five remote autobiographical memories from across the lifespan. Event transcriptions were segmented into distinct details, classified as either internal (episodic) or external (non-episodic). AD patients exhibited deficits in both remembering past events and simulating future events, generating fewer internal and external episodic details than healthy older controls. The internal and external detail scores were strongly correlated across past and future events, providing further evidence of the close linkages between the mental representations of past and future. PMID:19497331

  8. Algorithms for adaptive stochastic control for a class of linear systems

    NASA Technical Reports Server (NTRS)

    Toda, M.; Patel, R. V.

    1977-01-01

    Control of linear, discrete time, stochastic systems with unknown control gain parameters is discussed. Two suboptimal adaptive control schemes are derived: one is based on underestimating future control and the other is based on overestimating future control. Both schemes require little on-line computation and incorporate in their control laws some information on estimation errors. The performance of these laws is studied by Monte Carlo simulations on a computer. Two single input, third order systems are considered, one stable and the other unstable, and the performance of the two adaptive control schemes is compared with that of the scheme based on enforced certainty equivalence and the scheme where the control gain parameters are known.

  9. Future Tense and Economic Decisions: Controlling for Cultural Evolution

    PubMed Central

    Roberts, Seán G.; Winters, James; Chen, Keith

    2015-01-01

    A previous study by Chen demonstrates a correlation between languages that grammatically mark future events and their speakers' propensity to save, even after controlling for numerous economic and demographic factors. The implication is that languages which grammatically distinguish the present and the future may bias their speakers to distinguish them psychologically, leading to less future-oriented decision making. However, Chen's original analysis assumed languages are independent. This neglects the fact that languages are related, causing correlations to appear stronger than is warranted (Galton's problem). In this paper, we test the robustness of Chen's correlations to corrections for the geographic and historical relatedness of languages. While the question seems simple, the answer is complex. In general, the statistical correlation between the two variables is weaker when controlling for relatedness. When applying the strictest tests for relatedness, and when data is not aggregated across individuals, the correlation is not significant. However, the correlation did remain reasonably robust under a number of tests. We argue that any claims of synchronic patterns between cultural variables should be tested for spurious correlations, with the kinds of approaches used in this paper. However, experiments or case-studies would be more fruitful avenues for future research on this specific topic, rather than further large-scale cross-cultural correlational studies. PMID:26186527

  10. Future Tense and Economic Decisions: Controlling for Cultural Evolution.

    PubMed

    Roberts, Seán G; Winters, James; Chen, Keith

    2015-01-01

    A previous study by Chen demonstrates a correlation between languages that grammatically mark future events and their speakers' propensity to save, even after controlling for numerous economic and demographic factors. The implication is that languages which grammatically distinguish the present and the future may bias their speakers to distinguish them psychologically, leading to less future-oriented decision making. However, Chen's original analysis assumed languages are independent. This neglects the fact that languages are related, causing correlations to appear stronger than is warranted (Galton's problem). In this paper, we test the robustness of Chen's correlations to corrections for the geographic and historical relatedness of languages. While the question seems simple, the answer is complex. In general, the statistical correlation between the two variables is weaker when controlling for relatedness. When applying the strictest tests for relatedness, and when data is not aggregated across individuals, the correlation is not significant. However, the correlation did remain reasonably robust under a number of tests. We argue that any claims of synchronic patterns between cultural variables should be tested for spurious correlations, with the kinds of approaches used in this paper. However, experiments or case-studies would be more fruitful avenues for future research on this specific topic, rather than further large-scale cross-cultural correlational studies.

  11. Perceptions of vulnerability to a future outbreak: a study of horse managers affected by the first Australian equine influenza outbreak

    PubMed Central

    2013-01-01

    Background A growing body of work shows the benefits of applying social cognitive behavioural theory to investigate infection control and biosecurity practices. Protection motivation theory has been used to predict protective health behaviours. The theory outlines that a perception of a lack of vulnerability to a disease contributes to a reduced threat appraisal, which results in poorer motivation, and is linked to poorer compliance with advised health protective behaviours. This study, conducted following the first-ever outbreak of equine influenza in Australia in 2007, identified factors associated with horse managers’ perceived vulnerability to a future equine influenza outbreak. Results Of the 200 respondents, 31.9% perceived themselves to be very vulnerable, 36.6% vulnerable and 31.4% not vulnerable to a future outbreak of equine influenza. Multivariable logistic regression modelling revealed that managers involved in horse racing and those on rural horse premises perceived themselves to have low levels of vulnerability. Managers of horse premises that experienced infection in their horses in 2007 and those seeking infection control information from specific sources reported increased levels of perceived vulnerability to a future outbreak. Conclusion Different groups across the horse industry perceived differing levels of vulnerability to a future outbreak. Increased vulnerability contributes to favourable infection control behaviour and hence these findings are important for understanding uptake of recommended infection control measures. Future biosecurity communication strategies should be delivered through information sources suitable for the horse racing and rural sectors. PMID:23902718

  12. Momentary effects of exposure to prosmoking media on college students' future smoking risk.

    PubMed

    Shadel, William G; Martino, Steven C; Setodji, Claude; Scharf, Deborah

    2012-07-01

    This study used ecological momentary assessment to examine acute changes in college students' future smoking risk as a function of their exposure to prosmoking media (e.g., smoking in movies, paid advertising, point-of-sale displays). A sample of 135 college students ("ever" and "never" smokers) carried handheld computers for 21 days, recording their exposures to all forms of prosmoking media during the assessment period. They also responded to three investigator-initiated control prompts during each day of the assessment period (i.e., programmed to occur randomly). After each prosmoking media exposure and after each random control prompt they answered questions that measured their risk of future smoking. Responses between prosmoking media encounters were compared (within subjects) to responses made during random control prompts. Compliance with the study protocol was high, with participants responding to over 83% of all random prompts. Participants recorded nearly three encounters with prosmoking media each week. Results of linear mixed modeling indicated that all participants had higher future smoking risk following exposure to prosmoking media compared with control prompts (p < .05); this pattern of response did not differ between ever and never smokers (p = .769). Additional modeling of the variances around participants' risk of future smoking revealed that the response of never smokers to prosmoking media was significantly more variable than the response of ever smokers. Exposure to prosmoking media is associated with acute changes in future smoking risk, and never smokers and ever smokers respond differently to these exposures.

  13. Perceptions of vulnerability to a future outbreak: a study of horse managers affected by the first Australian equine influenza outbreak.

    PubMed

    Schemann, Kathrin; Firestone, Simon M; Taylor, Melanie R; Toribio, Jenny-Ann L M L; Ward, Michael P; Dhand, Navneet K

    2013-07-31

    A growing body of work shows the benefits of applying social cognitive behavioural theory to investigate infection control and biosecurity practices. Protection motivation theory has been used to predict protective health behaviours. The theory outlines that a perception of a lack of vulnerability to a disease contributes to a reduced threat appraisal, which results in poorer motivation, and is linked to poorer compliance with advised health protective behaviours. This study, conducted following the first-ever outbreak of equine influenza in Australia in 2007, identified factors associated with horse managers' perceived vulnerability to a future equine influenza outbreak. Of the 200 respondents, 31.9% perceived themselves to be very vulnerable, 36.6% vulnerable and 31.4% not vulnerable to a future outbreak of equine influenza. Multivariable logistic regression modelling revealed that managers involved in horse racing and those on rural horse premises perceived themselves to have low levels of vulnerability. Managers of horse premises that experienced infection in their horses in 2007 and those seeking infection control information from specific sources reported increased levels of perceived vulnerability to a future outbreak. Different groups across the horse industry perceived differing levels of vulnerability to a future outbreak. Increased vulnerability contributes to favourable infection control behaviour and hence these findings are important for understanding uptake of recommended infection control measures. Future biosecurity communication strategies should be delivered through information sources suitable for the horse racing and rural sectors.

  14. Improving brain-machine interface performance by decoding intended future movements

    NASA Astrophysics Data System (ADS)

    Willett, Francis R.; Suminski, Aaron J.; Fagg, Andrew H.; Hatsopoulos, Nicholas G.

    2013-04-01

    Objective. A brain-machine interface (BMI) records neural signals in real time from a subject's brain, interprets them as motor commands, and reroutes them to a device such as a robotic arm, so as to restore lost motor function. Our objective here is to improve BMI performance by minimizing the deleterious effects of delay in the BMI control loop. We mitigate the effects of delay by decoding the subject's intended movements a short time lead in the future. Approach. We use the decoded, intended future movements of the subject as the control signal that drives the movement of our BMI. This should allow the user's intended trajectory to be implemented more quickly by the BMI, reducing the amount of delay in the system. In our experiment, a monkey (Macaca mulatta) uses a future prediction BMI to control a simulated arm to hit targets on a screen. Main Results. Results from experiments with BMIs possessing different system delays (100, 200 and 300 ms) show that the monkey can make significantly straighter, faster and smoother movements when the decoder predicts the user's future intent. We also characterize how BMI performance changes as a function of delay, and explore offline how the accuracy of future prediction decoders varies at different time leads. Significance. This study is the first to characterize the effects of control delays in a BMI and to show that decoding the user's future intent can compensate for the negative effect of control delay on BMI performance.

  15. Prediction based active ramp metering control strategy with mobility and safety assessment

    NASA Astrophysics Data System (ADS)

    Fang, Jie; Tu, Lili

    2018-04-01

    Ramp metering is one of the most direct and efficient motorway traffic flow management measures so as to improve traffic conditions. However, owing to short of traffic conditions prediction, in earlier studies, the impact on traffic flow dynamics of the applied RM control was not quantitatively evaluated. In this study, a RM control algorithm adopting Model Predictive Control (MPC) framework to predict and assess future traffic conditions, which taking both the current traffic conditions and the RM-controlled future traffic states into consideration, was presented. The designed RM control algorithm targets at optimizing the network mobility and safety performance. The designed algorithm is evaluated in a field-data-based simulation. Through comparing the presented algorithm controlled scenario with the uncontrolled scenario, it was proved that the proposed RM control algorithm can effectively relieve the congestion of traffic network with no significant compromises in safety aspect.

  16. The relationship between future orientation and street substance use among Texas alternative school students.

    PubMed

    Peters, R J; Tortolero, Susan R; Johnson, Regina Jones; Addy, Robert C; Markham, Christine M; Escobar-Chaves, S Liliana; Lewis, Holly; Yacoubian, George S

    2005-01-01

    Self-reported substance use data were collected from 963 alternative school students in grades 7-12 who were surveyed through the Safer Choices 2 study in Houston, Texas. Data were collected between October 2000 and March 2001. Logistic regression analyses indicated that lower levels of future orientation was significantly associated (OR = 0.88, 95% CI = 0.81-0.97) with thirty-day substance use after controlling for age and gender. In addition, lower levels of future orientation was found to have a significant association with students' lifetime substance use (OR = 0.93, 95% CI = 0.87-.99) after controlling for age, race, and gender. While the relationships tested in this study are exploratory, they provide evidence for an important connection between future orientation and substance use among adolescents attending alternative schools.

  17. Do strategic processes contribute to the specificity of future simulation in depression?

    PubMed

    Addis, Donna Rose; Hach, Sylvia; Tippett, Lynette J

    2016-06-01

    The tendency to generate overgeneral past or future events is characteristic of individuals with a history of depression. Although much research has investigated the contribution of rumination and avoidance to the reduced specificity of past events, comparatively little research has examined (1) whether the specificity of future events is differentially reduced in depression and (2) the role of executive functions in this phenomenon. Our study aimed to redress this imbalance. Participants with either current or past experience of depressive symptoms ('depressive group'; N = 24) and matched controls ('control group'; N = 24) completed tests of avoidance, rumination, and executive functions. A modified Autobiographical Memory Test was administered to assess the specificity of past and future events. The depressive group were more ruminative and avoidant than controls, but did not exhibit deficits in executive function. Although overall the depressive group generated significantly fewer specific events than controls, this reduction was driven by a significant group difference in future event specificity. Strategic retrieval processes were correlated with both past and future specificity, and predictive of the future specificity, whereas avoidance and rumination were not. Our findings demonstrate that future simulation appears to be particularly vulnerable to disruption in individuals with current or past experience of depressive symptoms, consistent with the notion that future simulation is more cognitively demanding than autobiographical memory retrieval. Moreover, our findings suggest that even subtle changes in executive functions such as strategic processes may impact the ability to imagine specific future events. Future simulation may be particularly vulnerable to executive dysfunction in individuals with current/previous depressive symptoms, with evidence of a differential reduction in the specificity of future events. Strategic retrieval abilities were associated with the degree of future event specificity whereas levels of rumination and avoidance were not. Given that the ability to generate specific simulations of the future is associated with enhanced psychological wellbeing, problem solving and coping behaviours, understanding how to increase the specificity of future simulations in depression is an important direction for future research and clinical practice. Interventions focusing on improving the ability to engage strategic processes may be a fruitful avenue for increasing the ability to imagine specific future events in depression. The autobiographical event tasks have somewhat limited ecological validity as they do not account for the many social and environmental cues present in everyday life; the development of more clinically-relevant tasks may be of benefit to this area of study. © 2016 The British Psychological Society.

  18. Ego depletion and positive illusions: does the construction of positivity require regulatory resources?

    PubMed

    Fischer, Peter; Greitemeyer, Tobias; Frey, Dieter

    2007-09-01

    Individuals frequently exhibit positive illusions about their own abilities, their possibilities to control their environment, and future expectations. The authors propose that positive illusions require resources of self-control, which is considered to be a limited resource similar to energy or strength. Five studies revealed that people with depleted self-regulatory resources indeed exhibited a less-optimistic sense of their own abilities (Study 1), a lower sense of subjective control (Study 2), and less-optimistic expectations about their future (Study 3). Two further studies shed light on the underlying psychological process: Ego-depleted (compared to nondepleted) individuals generated/retrieved less positive self-relevant attributes (Studies 4 and 5) and reported a lower sense of general self-efficacy (Study 5), which both partially mediated the impact of ego depletion on positive self-views (Study 5).

  19. Control-Structure-Interaction (CSI) technologies and trends to future NASA missions

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Control-structure-interaction (CSI) issues which are relevant for future NASA missions are reviewed. This goal was achieved by: (1) reviewing large space structures (LSS) technologies to provide a background and survey of the current state of the art (SOA); (2) analytically studying a focus mission to identify opportunities where CSI technology may be applied to enhance or enable future NASA spacecraft; and (3) expanding a portion of the focus mission, the large antenna, to provide in-depth trade studies, scaling laws, and methodologies which may be applied to other NASA missions. Several sections are presented. Section 1 defines CSI issues and presents an overview of the relevant modeling and control issues for LLS. Section 2 presents the results of the three phases of the CSI study. Section 2.1 gives the results of a CSI study conducted with the Geostationary Platform (Geoplat) as the focus mission. Section 2.2 contains an overview of the CSI control design methodology available in the technical community. Included is a survey of the CSI ground-based experiments which were conducted to verify theoretical performance predictions. Section 2.3 presents and demonstrates a new CSI scaling law methodology for assessing potential CSI with large antenna systems.

  20. Momentary Effects of Exposure to Pro-Smoking Media on College Students’ Future Smoking Risk

    PubMed Central

    Shadel, William G.; Martino, Steven C.; Setodji, Claude; Scharf, Deborah

    2012-01-01

    Objective This study used ecological momentary assessment to examine acute changes in college students’ future smoking risk as a function of their exposure to pro-smoking media (e.g., smoking in movies, paid advertising, point-of-sale promotions). Methods A sample of 135 college students (ever and never smokers) carried handheld computers for 21 days, recording their exposures to all forms of pro-smoking media during the assessment period. They also responded to three investigator-initiated control prompts during each day of the assessment period (i.e., programmed to occur randomly). After each pro-media smoking exposure and after each random control prompt they answered questions that measured their risk of future smoking. Responses between pro-smoking media encounters were compared to responses made during random control prompts. Results Compliance with the study protocol was high, with participants responding to over 83% of all random prompts. Participants recorded nearly three encounters with pro-smoking media each week. Results of linear mixed modeling indicated that all participants had higher future smoking risk following exposure to pro-smoking media compared with control prompts (p < 0.05); this pattern of response did not differ between ever and never smokers (p = 0.769). Additional modeling of the variances around participants’ risk of future smoking revealed that the response of never smokers to pro-smoking media was significantly more variable than the response of ever smokers. Conclusions Exposure to pro-smoking media is associated with acute changes in future smoking risk, and never smokers and ever smokers respond differently to these exposures. PMID:22353027

  1. Increased risk of snoring and adenotonsillectomy in children referred for tympanostomy tube insertion.

    PubMed

    Tauman, Riva; Derowe, Ari; Ophir, Orna; Greenfeld, Michal; Sivan, Yakov

    2010-02-01

    Eustachian tube dysfunction and sleep-disordered breathing (SDB) share common pathophysiologic mechanisms. Our objective was to investigate whether children referred for isolated TTI (tympanostomy tube insertion) are at increased risk for snoring and upper airway procedures. Telephone interviews to parents of children who underwent isolated TTI and to age- and gender-matched controls were conducted. Four hundred fifty-seven children were included in the study; 352 had isolated TTI (study group) and 105 children were controls. Twenty-two percent of children in the study group were reported to snore compared with 7.6% in the controls (p=0.001). Eighteen percent of children in the study group were reported to have undergone adenotonsillectomy compared with 4.8% in the controls (p=0.0005). Future SDB, i.e., either snoring or adenotonsillectomy following TTI, was found in 34% of children in the study group compared with 11% in the controls (p=0.0004). Children who underwent isolated TTI were at increased risk for future snoring (OR=3.4, CI: 1.6-7.2) and future adenotonsillectomy (OR=4.4, CI: 1.7-11.2). Children who undergo isolated TTI are at increased risk for snoring and for adenotonsillectomy. We suggest that these children be followed for symptoms of SDB on a scheduled basis to allow for early diagnosis and intervention. 2009 Elsevier B.V. All rights reserved.

  2. A model for interprovincial air pollution control based on futures prices.

    PubMed

    Zhao, Laijun; Xue, Jian; Gao, Huaizhu Oliver; Li, Changmin; Huang, Rongbing

    2014-05-01

    Based on the current status of research on tradable emission rights futures, this paper introduces basic market-related assumptions for China's interprovincial air pollution control problem. The authors construct an interprovincial air pollution control model based on futures prices: the model calculated the spot price of emission rights using a classic futures pricing formula, and determined the identities of buyers and sellers for various provinces according to a partitioning criterion, thereby revealing five trading markets. To ensure interprovincial cooperation, a rational allocation result for the benefits from this model was achieved using the Shapley value method to construct an optimal reduction program and to determine the optimal annual decisions for each province. Finally, the Beijing-Tianjin-Hebei region was used as a case study, as this region has recently experienced serious pollution. It was found that the model reduced the overall cost of reducing SO2 pollution. Moreover, each province can lower its cost for air pollution reduction, resulting in a win-win solution. Adopting the model would therefore enhance regional cooperation and promote the control of China's air pollution. The authors construct an interprovincial air pollution control model based on futures prices. The Shapley value method is used to rationally allocate the cooperation benefit. Interprovincial pollution control reduces the overall reduction cost of SO2. Each province can lower its cost for air pollution reduction by cooperation.

  3. Flexibility decline contributes to similarity of past and future thinking in Alzheimer's disease.

    PubMed

    El Haj, Mohamad; Antoine, Pascal; Kapogiannis, Dimitrios

    2015-11-01

    A striking similarity has been suggested between past and future thinking in Alzheimer's Disease (AD), a similarity attributable to abnormalities in common modular cognitive functions and neuroanatomical substrates. This study extends this literature by identifying specific executive function deficits underlying past and future thinking in AD. Twenty-four participants with a clinical diagnosis of probable (mild) AD and 26 older controls generated past and future events and underwent tests of binding and the executive functions of flexibility, inhibition, and updating. AD patients showed similar autobiographical performances in past and future event generation, and so did control participants. In each group, the similarity of past and future thinking was predicted by flexibility. Furthermore, AD patients with low flexibility showed higher similarity of past and future thinking than those with high flexibility. These findings are interpreted in terms of involvement of the hippocampus and frontal lobes in future thinking. Deficits in these brain regions in AD are likely to compromise the ability to recombine episodic information into novel and flexible configurations as scenarios for the future. © 2015 Wiley Periodicals, Inc.

  4. Flexibility Decline Contributes to Similarity of Past and Future Thinking in Alzheimer’s Disease

    PubMed Central

    El Haj, Mohamad; Antoine, Pascal; Kapogiannis, Dimitrios

    2017-01-01

    A striking similarity has been suggested between past and future thinking in Alzheimer’s Disease (AD), a similarity attributable to abnormalities in common modular cognitive functions and neuroanatomical substrates. This study extends this literature by identifying specific executive function deficits underlying past and future thinking in AD. Twenty-four participants with a clinical diagnosis of probable (mild) AD and 26 older controls generated past and future events and underwent tests of binding and the executive functions of flexibility, inhibition, and updating. AD patients showed similar autobiographical performances in past and future event generation, and so did control participants. In each group, the similarity of past and future thinking was predicted by flexibility. Furthermore, AD patients with low flexibility showed higher similarity of past and future thinking than those with high flexibility. These findings are interpreted in terms of involvement of the hippocampus and frontal lobes in future thinking. Deficits in these brain regions in AD are likely to compromise the ability to recombine episodic information into novel and flexible configurations as scenarios for the future. PMID:25850800

  5. The performance of thermal control coatings on LDEF and implications to future spacecraft

    NASA Technical Reports Server (NTRS)

    Wilkes, Donald R.; Miller, Edgar R.; Mell, Richard J.; Lemaster, Paul S.; Zwiener, James M.

    1993-01-01

    The stability of thermal control coatings over the lifetime of a satellite or space platform is crucial to the success of the mission. With the increasing size, complexity, and duration of future missions, the stability of these materials becomes even more important. The Long Duration Exposure Facility (LDEF) offered an excellent testbed to study the stability and interaction of thermal control coatings in the low-Earth orbit (LEO) space environment. Several experiments on LDEF exposed thermal control coatings to the space environment. This paper provides an overview of the different materials flown and their stability during the extended LDEF mission. The exposure conditions, exposure environment, and measurements of materials properties (both in-space and postflight) are described. The relevance of the results and the implications to the design and operation of future space vehicles are also discussed.

  6. Dynamically Hedging Oil and Currency Futures Using Receding Horizontal Control and Stochastic Programming

    NASA Astrophysics Data System (ADS)

    Cottrell, Paul Edward

    There is a lack of research in the area of hedging future contracts, especially in illiquid or very volatile market conditions. It is important to understand the volatility of the oil and currency markets because reduced fluctuations in these markets could lead to better hedging performance. This study compared different hedging methods by using a hedging error metric, supplementing the Receding Horizontal Control and Stochastic Programming (RHCSP) method by utilizing the London Interbank Offered Rate with the Levy process. The RHCSP hedging method was investigated to determine if improved hedging error was accomplished compared to the Black-Scholes, Leland, and Whalley and Wilmott methods when applied on simulated, oil, and currency futures markets. A modified RHCSP method was also investigated to determine if this method could significantly reduce hedging error under extreme market illiquidity conditions when applied on simulated, oil, and currency futures markets. This quantitative study used chaos theory and emergence for its theoretical foundation. An experimental research method was utilized for this study with a sample size of 506 hedging errors pertaining to historical and simulation data. The historical data were from January 1, 2005 through December 31, 2012. The modified RHCSP method was found to significantly reduce hedging error for the oil and currency market futures by the use of a 2-way ANOVA with a t test and post hoc Tukey test. This study promotes positive social change by identifying better risk controls for investment portfolios and illustrating how to benefit from high volatility in markets. Economists, professional investment managers, and independent investors could benefit from the findings of this study.

  7. Comparative genomic analysis of novel bacteriophages infecting Vibrio parahaemolyticus isolated from western and southern coastal areas of Korea.

    PubMed

    Yu, Junhyeok; Lim, Jeong-A; Kwak, Su-Jin; Park, Jong-Hyun; Chang, Hyun-Joo

    2018-05-01

    Vibrio parahaemolyticus, a foodborne pathogen, has become resistant to antibiotics. Therefore, alternative bio-control agents such bacteriophage are urgently needed for its control. Six novel bacteriophages specific to V. parahaemolyticus (vB_VpaP_KF1~2, vB_VpaS_KF3~6) were characterized at the molecular level in this study. Genomic similarity analysis revealed that these six bacteriophages could be divided into two groups with different genomic features, phylogenetic grouping, and morphologies. Two groups of bacteriophages had their own genes with different mechanisms for infection, assembly, and metabolism. Our results could be used as a future reference to study phage genomics or apply phages in future bio-control studies.

  8. The cognitive bases of the development of past and future episodic cognition in preschoolers.

    PubMed

    Ünal, Gülten; Hohenberger, Annette

    2017-10-01

    The aim of this study was to use a minimalist framework to examine the joint development of past and future episodic cognition and their underlying cognitive abilities in 3- to 5-year-old Turkish preschoolers. Participants engaged in two main tasks, a what-where-when (www) task to measure episodic memory and a future prediction task to measure episodic future thinking. Three additional tasks were used for predicting children's performance in the two main tasks: a temporal language task, an executive function task, and a spatial working memory task. Results indicated that past and future episodic tasks were significantly correlated with each other even after controlling for age. Hierarchical multiple regressions showed that, after controlling for age, the www task was predicted by executive functions, possibly supporting binding of episodic information and by linguistic abilities. The future prediction task was predicted by linguistic abilities alone, underlining the importance of language for episodic past and future thinking. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Control of black walnut root rot diseases in nurseries.

    Treesearch

    Kenneth J. Jr. Kessler

    1982-01-01

    Current nursery methods used to control black walnut root rot diseases are considered in terms of integrated pest management. Suggestions for future root rot control research studies and procedures to minimize root rot problems are provided.

  10. AIDS Health Locus of Control, Self-Efficacy for Safer Sexual Practices, and Future Time Orientation as Predictors of Condom Use in African American College Students

    ERIC Educational Resources Information Center

    Burns, Myron J.; Dillon, Frank R.

    2005-01-01

    This study examined the relationship between self-reported frequency of condom use (by self or partner during the past 6 months and lifetime), locus of control, self-efficacy, and future time orientation among African American college students who were single and sexually active during the past year. Data were collected from 106 undergraduate…

  11. Progress in Aluminum Electrolysis Control and Future Direction for Smart Aluminum Electrolysis Plant

    NASA Astrophysics Data System (ADS)

    Zhang, Hongliang; Li, Tianshuang; Li, Jie; Yang, Shuai; Zou, Zhong

    2017-02-01

    The industrial aluminum reduction cell is an electrochemistry reactor that operates under high temperatures and highly corrosive conditions. However, these conditions have restricted the measurement of key control parameters, making the control of aluminum reduction cells a difficult problem in the industry. Because aluminum electrolysis control systems have a significant economic influence, substantial research has been conducted on control algorithms, control systems and information systems for aluminum reduction cells. This article first summarizes the development of control systems and then focuses on the progress made since 2000, including alumina concentration control, temperature control and electrolyte molecular ratio control, fault diagnosis, cell condition prediction and control system expansion. Based on these studies, the concept of a smart aluminum electrolysis plant is proposed. The frame construction, key problems and current progress are introduced. Finally, several future directions are discussed.

  12. Redundant actuator development study. [flight control systems for supersonic transport aircraft

    NASA Technical Reports Server (NTRS)

    Ryder, D. R.

    1973-01-01

    Current and past supersonic transport configurations are reviewed to assess redundancy requirements for future airplane control systems. Secondary actuators used in stability augmentation systems will probably be the most critical actuator application and require the highest level of redundancy. Two methods of actuator redundancy mechanization have been recommended for further study. Math models of the recommended systems have been developed for use in future computer simulations. A long range plan has been formulated for actuator hardware development and testing in conjunction with the NASA Flight Simulator for Advanced Aircraft.

  13. Self-control, future orientation, smoking, and the impact of Dutch tobacco control measures.

    PubMed

    Daly, Michael; Delaney, Liam; Baumeister, Roy F

    2015-06-01

    The pronounced discrepancy between smokers' intentions to quit and their smoking behavior has led researchers to suggest that many smokers are time inconsistent, have self-control problems, and may benefit from external efforts to constrain their consumption. This study aims to test whether self-control and future orientation predict smoking levels and to identify if these traits modify how cigarette consumption responds to the introduction of tobacco control measures. A sample of Dutch adults (N = 1585) completed a measure of self-control and the Consideration of Future Consequences Scale (CFCS) in 2001 and indicated their tobacco consumption each year from 2001 to 2007. In 2004, a workplace smoking ban and substantial tax increase on tobacco was introduced in the Netherlands. To identify the potential impact of these tobacco control measures we examined whether participants smoked or were heavy smokers (20 + cigarettes per day) each year from 2001 to 2007. Participants with high self-control and CFCS scores showed lower rates of smoking across the seven year period of the study. The 2004 smoking restrictions were linked with a subsequent decline in heavy smoking. This decline was moderated by self-control levels. Those with low self-control showed a large reduction in heavy smoking whereas those with high self-control did not. The effects were, however, temporary: many people with low self-control resumed heavy smoking 2-3 years after the introduction of the tobacco restrictions. The immediate costs which national tobacco control measures impose on smokers may assist smokers with poor self-control in reducing their cigarette consumption.

  14. The Medial Temporal Lobes are Critical for Reward-Based Decision Making under Conditions that Promote Episodic Future Thinking

    PubMed Central

    Palombo, Daniela J.; Keane, Margaret M.; Verfaellie, Mieke

    2014-01-01

    In the present study, we investigated the effect of medial temporal lobe (MTL) damage on human decision making in the context of reward-based intertemporal choice. During intertemporal choice, humans typically devalue (or discount) a future reward to account for its delayed arrival (e.g., preferring $30 now over $42 in 2 months), but this effect is attenuated when participants engage in episodic future thinking, i.e., project themselves into the future to imagine a specific event. We hypothesized that this attenuation would be selectively impaired in amnesic patients, who have deficits in episodic future thinking. Replicating previous work, in a standard intertemporal choice task, amnesic patients showed temporal discounting indices similar to healthy controls. Consistent with our hypothesis, while healthy controls demonstrated attenuated temporal discounting in a condition that required participants first to engage in episodic future thinking (e.g., to imagine spending $42 at a theatre in 2 months), amnesic patients failed to demonstrate this effect. Moreover, as expected, amnesic patients’ narratives were less episodically rich than those of controls. These findings extend the range of tasks that are shown to be MTL dependent to include not only memory-based decision-making tasks but also future-oriented ones. PMID:25284804

  15. Time perspective as a predictor of smoking status: findings from the International Tobacco Control (ITC) Surveys in Scotland, France, Germany, China, and Malaysia.

    PubMed

    Sansone, Genevieve; Fong, Geoffrey T; Hall, Peter A; Guignard, Romain; Beck, François; Mons, Ute; Pötschke-Langer, Martina; Yong, Hua-Hie; Thompson, Mary E; Omar, Maizurah; Jiang, Yuan

    2013-04-15

    Prior studies have demonstrated that time perspective-the propensity to consider short-versus long-term consequences of one's actions-is a potentially important predictor of health-related behaviors, including smoking. However, most prior studies have been conducted within single high-income countries. The aim of this study was to examine whether time perspective was associated with the likelihood of being a smoker or non-smoker across five countries that vary in smoking behavior and strength of tobacco control policies. The data were from the International Tobacco Control (ITC) Surveys in five countries with large probability samples of both smokers (N=10,341) and non-smokers (N=4,955): Scotland, France, Germany, China, and Malaysia. The surveys were conducted between 2005-2008. Survey respondents indicated their smoking status (smoker vs. non-smoker) and time perspective (future oriented vs. not future-oriented) and provided demographic information. Across all five countries, non-smokers were significantly more likely to be future-oriented (66%) than were smokers (57%), χ(2)(1, N = 15,244) = 120.64, p < .001. This bivariate relationship between time perspective and smoking status held in a multivariate analysis. After controlling for country, age, sex, income, education, and ethnicity (language in France), those who were future-oriented had 36% greater odds of being a non-smoker than a smoker (95% CI: 1.22 to 1.51, p<.001). These findings establish time perspective as an important predictor of smoking status across multiple countries and suggest the potential value of incorporating material to enhance future orientation in smoking cessation interventions.

  16. Time perspective as a predictor of smoking status: findings from the International Tobacco Control (ITC) Surveys in Scotland, France, Germany, China, and Malaysia

    PubMed Central

    2013-01-01

    Background Prior studies have demonstrated that time perspective—the propensity to consider short-versus long-term consequences of one’s actions—is a potentially important predictor of health-related behaviors, including smoking. However, most prior studies have been conducted within single high-income countries. The aim of this study was to examine whether time perspective was associated with the likelihood of being a smoker or non-smoker across five countries that vary in smoking behavior and strength of tobacco control policies. Methods The data were from the International Tobacco Control (ITC) Surveys in five countries with large probability samples of both smokers (N=10,341) and non-smokers (N=4,955): Scotland, France, Germany, China, and Malaysia. The surveys were conducted between 2005–2008. Survey respondents indicated their smoking status (smoker vs. non-smoker) and time perspective (future oriented vs. not future-oriented) and provided demographic information. Results Across all five countries, non-smokers were significantly more likely to be future-oriented (66%) than were smokers (57%), χ2(1, N = 15,244) = 120.64, p < .001. This bivariate relationship between time perspective and smoking status held in a multivariate analysis. After controlling for country, age, sex, income, education, and ethnicity (language in France), those who were future-oriented had 36% greater odds of being a non-smoker than a smoker (95% CI: 1.22 to 1.51, p<.001). Conclusion These findings establish time perspective as an important predictor of smoking status across multiple countries and suggest the potential value of incorporating material to enhance future orientation in smoking cessation interventions. PMID:23587205

  17. Recent progress and future direction of cancer epidemiological research in Japan.

    PubMed

    Sobue, Tomotaka

    2015-06-01

    In 2006, the Cancer Control Act was approved and a Basic Plan, to Promote the Cancer Control Program at the national level, was developed in 2007. Cancer research is recognized as a fundamental component to provide evidence in cancer control program. Cancer epidemiology plays central role in connecting research and policy, since it directly deals with data from humans. Research for cancer epidemiology in Japan made substantial progress, in the field of descriptive studies, cohort studies, intervention studies and activities for summarizing evidences. In future, promoting high-quality large-scale intervention studies, individual-level linkage studies, simulation models and studies for elderly population will be of great importance, but at the same time research should be promoted in well-balanced fashion not placing too much emphasis on one particular research field. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Evidence of the Value of the Smoking Media Literacy Framework for Middle School Students.

    PubMed

    Bier, Melinda C; Zwarun, Lara; Sherblom, Stephen A

    2016-10-01

    Susceptibility to future smoking, positive beliefs about smoking, and perceptions of antismoking norms are all factors that are associated with future smoking. In previous research, smoking media literacy (SML) has been associated with these variables, even when controlling for other known risk factors for smoking. However, these studies were performed with older teenagers, often in high school, not younger teens at a crucial developmental point with respect to the decision to begin smoking. This study uses survey data collected from 656 American public middle school students representing multiple zip codes, schools, and school districts. Smoking media literacy levels for middle school students were similar to those of high school students in earlier studies. Higher SML levels were associated with lower susceptibility to future smoking and predicted susceptibility to smoke when controlling for other risk factors. This suggests that the same relationships found with teenagers may exist with middle school students. Although follow-up studies using larger and more controlled administrations of the SML scale are warranted, this study suggests the utility of the SML framework and scale in the development and investigation of media literacy as a prevention strategy in students this age. © 2016, American School Health Association.

  19. Synthesis Study on Transitions in Signal Infrastructure and Control Algorithms for Connected and Automated Transportation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aziz, H. M. Abdul; Wang, Hong; Young, Stan

    Documenting existing state of practice is an initial step in developing future control infrastructure to be co-deployed for heterogeneous mix of connected and automated vehicles with human drivers while leveraging benefits to safety, congestion, and energy. With advances in information technology and extensive deployment of connected and automated vehicle technology anticipated over the coming decades, cities globally are making efforts to plan and prepare for these transitions. CAVs not only offer opportunities to improve transportation systems through enhanced safety and efficient operations of vehicles. There are also significant needs in terms of exploring how best to leverage vehicle-to-vehicle (V2V) technology,more » vehicle-to-infrastructure (V2I) technology and vehicle-to-everything (V2X) technology. Both Connected Vehicle (CV) and Connected and Automated Vehicle (CAV) paradigms feature bi-directional connectivity and share similar applications in terms of signal control algorithm and infrastructure implementation. The discussion in our synthesis study assumes the CAV/CV context where connectivity exists with or without automated vehicles. Our synthesis study explores the current state of signal control algorithms and infrastructure, reports the completed and newly proposed CV/CAV deployment studies regarding signal control schemes, reviews the deployment costs for CAV/AV signal infrastructure, and concludes with a discussion on the opportunities such as detector free signal control schemes and dynamic performance management for intersections, and challenges such as dependency on market adaptation and the need to build a fault-tolerant signal system deployment in a CAV/CV environment. The study will serve as an initial critical assessment of existing signal control infrastructure (devices, control instruments, and firmware) and control schemes (actuated, adaptive, and coordinated-green wave). Also, the report will help to identify the future needs for the signal infrastructure to act as the nervous system for urban transportation networks, providing not only signaling, but also observability, surveillance, and measurement capacity. The discussion of the opportunities space includes network optimization and control theory perspectives, and the current states of observability for key system parameters (what can be detected, how frequently can it be reported) as well as controllability of dynamic parameters (this includes adjusting not only the signal phase and timing, but also the ability to alter vehicle trajectories through information or direct control). The perspective of observability and controllability of the dynamic systems provides an appropriate lens to discuss future directions as CAV/CV become more prevalent in the future.« less

  20. Does Problem Behavior Elicit Poor Parenting?: A Prospective Study of Adolescent Girls

    PubMed Central

    Huh, David; Tristan, Jennifer; Wade, Emily; Stice, Eric

    2006-01-01

    This study tested the hypothesis that perceived parenting would show reciprocal relations with adolescents' problem behavior using longitudinal data from 496 adolescent girls. Results provided support for the assertion that female problem behavior has an adverse effect on parenting; elevated externalizing symptoms and substance abuse symptoms predicted future decreases in perceived parental support and control. There was less support for the assertion that parenting deficits foster adolescent problem behaviors; initially low parental control predicted future increases in substance abuse, but not externalizing symptoms, and low parental support did not predict future increases in externalizing or substance abuse symptoms. Results suggest that problem behavior is a more consistent predictor of parenting than parenting is of problem behavior, at least for girls during middle adolescence. PMID:16528407

  1. Physiological Studies and Pest Control

    ERIC Educational Resources Information Center

    Philogene, Bernard J. R.

    1972-01-01

    In the light of new knowledge about insecticides, future research should be conducted by plant and insect physiologists together. Plant physiologists should explain what characteristics in plants attract insects and insect physiologists should study adaptive patterns of insects and combine their knowledge to control insects. (PS)

  2. Study of industry information requirements for flight control and navigation systems of STOL aircraft

    NASA Technical Reports Server (NTRS)

    Gorham, J. A.

    1976-01-01

    Answers to specific study questions are used to ascertain the data requirements associated with a guidance, navigation and control system for a future civil STOL airplane. Results of the study were used to recommend changes for improving the outputs of the STOLAND flight experiments program.

  3. Retrieval of past and future positive and negative autobiographical experiences.

    PubMed

    García-Bajos, Elvira; Migueles, Malen

    2017-09-01

    We studied retrieval-induced forgetting for past or future autobiographical experiences. In the study phase, participants were given cues to remember past autobiographical experiences or to think about experiences that may occur in the future. In both conditions, half of the experiences were positive and half negative. In the retrieval-practice phase, for past and future experiences, participants retrieved either half of the positive or negative experiences using cued recall, or capitals of the world (control groups). Retrieval practice produced recall facilitation and enhanced memory for the practised positive and negative past and future experiences. While retrieval practice on positive experiences did not impair the recall of other positive experiences, we found inhibition for negative past and future experiences when participants practised negative experiences. Furthermore, retrieval practice on positive future experiences inhibited negative future experiences. These positivity biases for autobiographical memory may have practical implications for treatment of emotional disorders.

  4. A Study of Risk Factors in Recidivistic Criminals

    PubMed Central

    Tiwari, S.C.; Gupta, S. C.; Shukla, Seema; Srivastava, Shipra; Pandey, Mamta; Maurya, Amit; Kumar, Aditya

    2004-01-01

    A study was carried out under the aegis of Indian Council of Medical Research, New Delhi with objectives to identify psychosocial, physical, psychiatric, anthropometric and psychometric risk factors in recidivistic criminals, which could predict a future recidivistic criminal. The paper presents study observations on 250 experimental, 250 control-1 and 250 control-2 subjects. Experimental and control-1 subjects were recruited from district jails of Uttar Pradesh and control-2 from the community. Pretested Semi-structured proformae, Verghese and Beig Symptoms Checklist, International Personality Disorder Examination module, Hostility and Direction of Hostility Questionnaire, Rorschach Ink Blot Test and Standard Anthropometric instruments were used to collect data on study probands. All the three groups were compared using Analysis of Variance and Chi-Square Test. The results highlight a number of psycho-social, psychiatric, psychometric and anthropometric factors which were found to have significant association with recidivistic criminal behaviour. The findings would not only help in identifying future recidivistic criminals but can also be used for legal, judicial, interventional and corrective purposes. PMID:21408043

  5. A Study of Economical Incentives for Voltage Profile Control Method in Future Distribution Network

    NASA Astrophysics Data System (ADS)

    Tsuji, Takao; Sato, Noriyuki; Hashiguchi, Takuhei; Goda, Tadahiro; Tange, Seiji; Nomura, Toshio

    In a future distribution network, it is difficult to maintain system voltage because a large number of distributed generators are introduced to the system. The authors have proposed “voltage profile control method” using power factor control of distributed generators in the previous work. However, the economical disbenefit is caused by the active power decrease when the power factor is controlled in order to increase the reactive power. Therefore, proper incentives must be given to the customers that corporate to the voltage profile control method. Thus, in this paper, we develop a new rules which can decide the economical incentives to the customers. The method is tested in one feeder distribution network model and its effectiveness is shown.

  6. Perspectives on advance care planning among patients recently requiring non-invasive ventilation for acute respiratory failure: A qualitative study using thematic analysis.

    PubMed

    Smith, Tracy A; Disler, Rebecca T; Jenkins, Christine R; Ingham, Jane M; Davidson, Patricia M

    2017-06-01

    Patients requiring non-invasive ventilation for acute-on-chronic respiratory failure due to chronic obstructive pulmonary disease or heart failure exacerbations may have a poor prognosis underscoring the importance of advance care planning. We aimed to describe attitudes to, and experiences of, discussing the future among patients recently treated with non-invasive ventilation. Qualitative research using thematic analysis. Tertiary teaching hospital. Patients with acute hypercapnic respiratory failure requiring non-invasive ventilation. Individuals recently treated with non-invasive ventilation describe feeling the future is beyond their control and instead controlled by their illness. Participants often recognised their poor prognosis but avoided discussing some difficult topics. The majority preferred not to undergo cardiopulmonary resuscitation but most had not discussed this with healthcare professionals. When participants voiced concerns about their future health to family members, they were met with polarised responses. Some encountered willingness for further discussion, while others met deflection, deterring further conversation. An overarching narrative of 'Looking through my illness to an uncertain but concerning future' unites these themes. This study suggests opportunities and barriers for advance care planning in individuals with chronic disease. Patients' understanding of their prognosis and their attitudes to cardiopulmonary resuscitation suggests an opportunity for advance care planning. Structuring discussions around patients' preferences for care during future exacerbations may foster a sense of control over the future despite illness. The diversity of familial responses to patients' concerns about their future health has implications for advance care planning. These findings have the potential to improve care for patients with respiratory failure and suggest an important ongoing research agenda.

  7. Cognitive bias in back pain patients attending osteopathy: testing the enmeshment model in reference to future thinking.

    PubMed

    Read, Jessica; Pincus, Tamar

    2004-12-01

    Depressive symptoms are common in chronic pain. Previous research has found differences in information-processing biases in depressed pain patients and depressed people without pain. The schema enmeshment model of pain (SEMP) has been proposed to explain chronic pain patients' information-processing biases. Negative future thinking is common in depression but has not been explored in relation to chronic pain and information-processing models. The study aimed to test the SEMP with reference to future thinking. An information-processing paradigm compared endorsement and recall bias between depressed and non-depressed chronic low back pain patients and control participants. Twenty-five depressed and 35 non-depressed chronic low back pain patients and 25 control participants (student osteopaths) were recruited from an osteopathy practice. Participants were asked to endorse positive and negative ill-health, depression-related, and neutral (control) adjectives, encoded in reference to either current or future time-frame. Incidental recall of the adjectives was then tested. While the expected hypothesis of a recall bias by depressed pain patients towards ill-health stimuli in the current condition was confirmed, the recall bias was not present in the future condition. Additionally, patterns of endorsement and recall bias differed. Results extend understanding of future thinking in chronic pain within the context of the SEMP.

  8. Future Orientation, Impulsivity, and Problem Behaviors: A Longitudinal Moderation Model

    ERIC Educational Resources Information Center

    Chen, Pan; Vazsonyi, Alexander T.

    2011-01-01

    In the current study, based on a sample of 1,873 adolescents between 11.4 and 20.9 years of age from the first 3 waves of the National Longitudinal Study of Adolescent Health, we investigated the longitudinal effects of future orientation on levels of and developmental changes in problem behaviors, while controlling for the effects by impulsivity;…

  9. The 747 primary flight control systems reliability and maintenance study

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The major operational characteristics of the 747 Primary Flight Control Systems (PFCS) are described. Results of reliability analysis for separate control functions are presented. The analysis makes use of a NASA computer program which calculates reliability of redundant systems. Costs for maintaining the 747 PFCS in airline service are assessed. The reliabilities and cost will provide a baseline for use in trade studies of future flight control system design.

  10. Smoking behaviours and attitudes toward tobacco control among assistant environmental health officer trainees.

    PubMed

    Tee, G H; Gurpreet, K; Hairi, N N; Zarihah, Z; Fadzilah, K

    2013-12-01

    Assistant environmental health officers (AEHO) are health care providers (HCPs) who act as enforcers, educators and trusted role models for the public. This is the first study to explore smoking behaviour and attitudes toward tobacco control among future HCPs. Almost 30% of AEHO trainees did not know the role of AEHOs in counselling smokers to stop smoking, but 91% agreed they should not smoke before advising others not to do so. The majority agreed that tobacco control regulations may be used as a means of reducing the prevalence of smoking. Future AEHOs had positive attitudes toward tobacco regulations but lacked understanding of their responsibility in tobacco control measures.

  11. Behavioral Response Research Evaluation Workshop (BRREW)

    DTIC Science & Technology

    2015-09-30

    future research directions, focusing on controlled exposure experiments ( captive and free-ranging animals) and observational studies. OBJECTIVES...in key areas including controlled exposure experiments ( captive and free-ranging animals) and observational studies on real Navy exercises; 2...include response to simulated sources of Navy sonar (BRS and captive studies), response to real Navy sources (BRS studies, M3R), incidental response

  12. Nuclear electric propulsion reactor control systems status

    NASA Technical Reports Server (NTRS)

    Ferg, D. A.

    1973-01-01

    The thermionic reactor control system design studies conducted over the past several years for a nuclear electric propulsion system are described and summarized. The relevant reactor control system studies are discussed in qualitative terms, pointing out the significant advantages and disadvantages including the impact that the various control systems would have on the nuclear electric propulsion system design. A recommendation for the reference control system is made, and a program for future work leading to an engineering model is described.

  13. Remote sensing and disease control in China: past, present and future

    PubMed Central

    2013-01-01

    Satellite measurements have distinct advantages over conventional ground measurements because they can collect the information repeatedly and automatically. Since 1970 globally and 1985 in China, the availability of remote sensing (RS) techniques has steadily grown and they are becoming increasingly important to improve our understanding of human health. This paper gives the first detailed overview on the developments of RS applications for disease control in China. The problems, challenges and future directions are also discussed with an aim of guiding prospective studies. PMID:23311958

  14. Market Research: Better Documentation Needed to Inform Future Procurements at Selected Agencies

    DTIC Science & Technology

    2014-10-01

    MARKET RESEARCH Better Documentation Needed to Inform Future Procurements at Selected Agencies Report to the...currently valid OMB control number. 1. REPORT DATE OCT 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Market ...2014 MARKET RESEARCH Better Documentation Needed to Inform Future Procurements at Selected Agencies is Why GAO Did This Study The federal

  15. A Longitudinal Study of Adolescents' Future Orientation (Time Perspective).

    ERIC Educational Resources Information Center

    Trommsdorff, Gisela; And Others

    1979-01-01

    Vocational or college-bound students responded to four futures orientation variables (personality, physical well-being, family, and occupation) along several dimensions, including hopes and fears, locus of control, and optimism. The same students took the same survey two years later. Age, sex, and educational status differences were noted. (CP)

  16. Baseline Study Methodology for Future Phases of Research on Nuclear Power Plant Control Room Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Le Blanc, Katya Lee; Bower, Gordon Ross; Hill, Rachael Ann

    In order to provide a basis for industry adoption of advanced technologies, the Control Room Upgrades Benefits Research Project will investigate the benefits of including advanced technologies as part of control room modernization This report describes the background, methodology, and research plan for the first in a series of full-scale studies to test the effects of advanced technology in NPP control rooms. This study will test the effect of Advanced Overview Displays in the partner Utility’s control room simulator

  17. Situation awareness in air traffic control : enhanced displays for advanced operations

    DOT National Transportation Integrated Search

    2000-01-01

    Future changes in the National Airspace System indicate a self-separation operational concept. This study examined the Air Traffic : Control Specialists ability to maintain situation awareness and provide needed monitoring and separation functions...

  18. Epigenetic Control of Prolyl and Asparaginyl Hydroxylases in Prostate Cancer

    DTIC Science & Technology

    2011-07-01

    transcriptionally and translationally silenced. We therefore proposed a study that focuses on the epigenetic control of these crucial enzymes . In this report...control of these enzymes . Last, we will explain our future direction of the project after the award period has expired. Hypoxia Inducible Factor, HIF...silenced. We therefore proposed a study that focuses on the epigenetic control of these crucial enzymes . In this report, we present data demonstrating our

  19. High-resolution dynamical downscaling of the future Alpine climate

    NASA Astrophysics Data System (ADS)

    Bozhinova, Denica; José Gómez-Navarro, Juan; Raible, Christoph

    2017-04-01

    The Alpine region and Switzerland is a challenging area for simulating and analysing Global Climate Model (GCM) results. This is mostly due to the combination of a very complex topography and the still rather coarse horizontal resolution of current GCMs, in which not all of the many-scale processes that drive the local weather and climate can be resolved. In our study, the Weather Research and Forecasting (WRF) model is used to dynamically downscale a GCM simulation to a resolution as high as 2 km x 2 km. WRF is driven by initial and boundary conditions produced with the Community Earth System Model (CESM) for the recent past (control run) and until 2100 using the RCP8.5 climate scenario (future run). The control run downscaled with WRF covers the period 1976-2005, while the future run investigates a 20-year-slice simulated for the 2080-2099. We compare the control WRF-CESM simulations to an observational product provided by MeteoSwiss and an additional WRF simulation driven by the ERA-Interim reanalysis, to estimate the bias that is introduced by the extra modelling step of our framework. Several bias-correction methods are evaluated, including a quantile mapping technique, to ameliorate the bias in the control WRF-CESM simulation. In the next step of our study these corrections are applied to our future WRF-CESM run. The resulting downscaled and bias-corrected data is analysed for the properties of precipitation and wind speed in the future climate. Our special interest focuses on the absolute quantities simulated for these meteorological variables as these are used to identify extreme events, such as wind storms and situations that can lead to floods.

  20. Exercise and mental health: a review.

    PubMed

    Glenister, D

    1996-02-01

    With the advent of programmes to raise the level of fitness in the general population, and alliances between primary health care and community leisure services, the potential of exercise in promoting mental as well as physical health deserves investigation. In contrast to USA and continental Europe, there is a paucity of British research studies systematically exploring the mental health benefits of exercise. The recent rapid growth of exercise prescription among general practitioners presents an opportunity for future research. This review of eleven randomised control trials (RCTs) suggests a causal relationship between exercise and mental health based upon studies in various settings. The methodological difficulties associated with randomised control trials of psycho-social interventions are discussed. The value of future randomised control trials which incorporate examination of perceived acceptability and health economics is indicated.

  1. Chemosterilants for Control of Insects and Insect Vectors of Disease.

    PubMed

    Baxter, Richard H G

    2016-10-01

    Both historically and at present, vector control is the most generally effective means of controlling malaria transmission. Insecticides are the predominant method of vector control, but the sterile insect technique (SIT) is a complementary strategy with a successful track record in both agricultural and public health sectors. Strategies of genetic and radiation-induced sterilization of Anopheles have to date been limited by logistical and/or regulatory hurdles. A safe and effective mosquito chemosterilant would therefore be of major utility to future deployment of SIT for malaria control. Here we review the prior and current use of chemosterilants in SIT, and assess the potential for future research. Recent genomic and proteomic studies reveal opportunities for specific targeting of seminal fluid proteins, and the capacity to interfere with sperm motility and storage in the female.

  2. Manpower Needs in Environmental Management. Research Report of a Graduate Study.

    ERIC Educational Resources Information Center

    Hillison, John H.; Warmbrod, J. Robert

    This report summarizes a study designed to assess current and future manpower needs in wastewater treatment, water treatment, and air pollution control, as well as perform task analyses for the purpose of developing courses of study and instructional materials. Data were collected by means of interviews for all 10 air pollution control areas in…

  3. Research study: Space vehicle control systems

    NASA Technical Reports Server (NTRS)

    Likins, P. W.; Longman, R. W.

    1979-01-01

    From the control point of view, spacecraft are classified into two main groups: those for which the spacecraft is fully defined before the control system is designed; and those for which the control system must be specified before certain interchangeable parts of a multi-purpose spacecraft are selected for future missions. Consideration is given to both classes of problems.

  4. Space Station Environment Control and Life Support System Pressure Control Pump Assembly Modeling and Analysis

    NASA Technical Reports Server (NTRS)

    Schunk, R. Gregory

    2002-01-01

    This paper presents the Modeling and Analysis of the Space Station Environment Control and Life Support System Pressure Control Pump Assembly (PCPA). The contents include: 1) Integrated PCPA/Manifold Analyses; 2) Manifold Performance Analysis; 3) PCPA Motor Heat Leak Study; and 4) Future Plans. This paper is presented in viewgraph form.

  5. Future orientation, impulsivity, and problem behaviors: a longitudinal moderation model.

    PubMed

    Chen, Pan; Vazsonyi, Alexander T

    2011-11-01

    In the current study, based on a sample of 1,873 adolescents between 11.4 and 20.9 years of age from the first 3 waves of the National Longitudinal Study of Adolescent Health, we investigated the longitudinal effects of future orientation on levels of and developmental changes in problem behaviors, while controlling for the effects by impulsivity; we also tested the moderating effects by future orientation on the impulsivity-problem behaviors link over time. Additionally, we examined future orientation operationalized by items measuring education, marriage, and life domains. Findings based on growth curve analyses provided evidence of longitudinal effects by education and life future orientation on both levels of and developmental changes in problem behaviors; the effect of marriage future orientation was not significant for either test. In addition, only life future orientation moderated the effect by impulsivity on levels of problem behaviors over time. More specifically, impulsivity had a weaker effect on levels of problem behaviors over time for adolescents who reported higher levels of life future orientation.

  6. Economic evaluations and their use in infection prevention and control: a narrative review.

    PubMed

    Rennert-May, Elissa; Conly, John; Leal, Jenine; Smith, Stephanie; Manns, Braden

    2018-01-01

    The objective of this review is to provide a comprehensive overview of the different types of economic evaluations that can be utilized by Infection Prevention and Control practitioners with a particular focus on the use of the quality adjusted life year, and its associated challenges. We also highlight existing economic evaluations published within Infection Prevention and Control, research gaps and future directions. Narrative Review. To date the majority of economic evaluations within Infection Prevention and Control are considered partial economic evaluations. Acknowledging the challenges, which include variable utilities within infection prevention and control, a lack of randomized controlled trials, and difficulty in modelling infectious diseases in general, future economic evaluation studies should strive to be consistent with published guidelines for economic evaluations. This includes the use of quality adjusted life years. Further research is required to estimate utility scores of relevance within Infection Prevention and Control.

  7. Dimensionality of coping and its relation to depression.

    PubMed

    Rohde, P; Lewinsohn, P M; Tilson, M; Seeley, J R

    1990-03-01

    The dimensionality of coping, as measured by 65 items from 3 commonly used instruments, and the relation of coping and stress to concurrent and future depression were studied in a community sample of 742 older (greater than or equal to 50 years old) adults. Measures of coping, stress, and depression were obtained at 2 time points over a 2-year period. Depression was assessed by symptom checklist and by diagnostic interview. Three coping factors--Cognitive Self-Control, Ineffective Escapism, and Solace Seeking--that had adequate psychometric properties and accounted for 25% of the total item variance were identified. Ineffective Escapism was associated with current depression and had a direct and interactive effect on future depression, exacerbating the negative impact of stress rather than acting as a buffer. Although Cognitive Self-Control was unrelated to either concurrent or future depression, Solace Seeking significantly buffered the effect of stress in predicting a future diagnosis of depression. Stress and initial depression level predicted both measures of future depression. Gender (being female) predicted the future diagnosis of depression but not the increase of depressive symptoms.

  8. Acting with the future in mind is impaired in long-term opiate users.

    PubMed

    Terrett, Gill; Lyons, Amanda; Henry, Julie D; Ryrie, Clare; Suddendorf, Thomas; Rendell, Peter G

    2017-01-01

    Episodic foresight is a fundamental human capacity. It refers to the ability to simulate future situations and organise current actions accordingly. While there is some evidence that opiate users have a reduced capacity to imagine themselves in future situations, no study to date has assessed whether opiate users show deficits in the ability to take steps in the present in anticipation of future needs. In this study, we assessed whether this functional aspect of episodic foresight is impaired in chronic opiate users and the extent to which any deficits are associated with executive dysfunction. Participants were 33 long-term opiate users enrolled in an opiate substitution program and 34 controls. Relative to controls, the opiate users displayed significant impairment (medium effect size η 2 p  = 0.08) in the two behavioural measures of episodic foresight used (items acquired and items used in the VW Foresight task). Furthermore, executive functioning was associated with foresight ability, although this was restricted to items acquired, and the associations were generally stronger for the control group. These data provide important evidence suggesting that the functional aspect of episodic foresight is disrupted in long-term opiate users. While these deficits appear to have some links to impaired executive control, additional work is needed to gain a more complete understanding of the underlying cognitive and neural mechanisms involved. This, in turn, will have important implications for tailoring interventions with opiate users to maximise the likelihood of successful independent functioning.

  9. Urinary Sugars--A Biomarker of Total Sugars Intake.

    PubMed

    Tasevska, Natasha

    2015-07-15

    Measurement error in self-reported sugars intake may explain the lack of consistency in the epidemiologic evidence on the association between sugars and disease risk. This review describes the development and applications of a biomarker of sugars intake, informs its future use and recommends directions for future research. Recently, 24 h urinary sucrose and fructose were suggested as a predictive biomarker for total sugars intake, based on findings from three highly controlled feeding studies conducted in the United Kingdom. From this work, a calibration equation for the biomarker that provides an unbiased measure of sugars intake was generated that has since been used in two US-based studies with free-living individuals to assess measurement error in dietary self-reports and to develop regression calibration equations that could be used in future diet-disease analyses. Further applications of the biomarker include its use as a surrogate measure of intake in diet-disease association studies. Although this biomarker has great potential and exhibits favorable characteristics, available data come from a few controlled studies with limited sample sizes conducted in the UK. Larger feeding studies conducted in different populations are needed to further explore biomarker characteristics and stability of its biases, compare its performance, and generate a unique, or population-specific biomarker calibration equations to be applied in future studies. A validated sugars biomarker is critical for informed interpretation of sugars-disease association studies.

  10. Urinary Sugars—A Biomarker of Total Sugars Intake

    PubMed Central

    Tasevska, Natasha

    2015-01-01

    Measurement error in self-reported sugars intake may explain the lack of consistency in the epidemiologic evidence on the association between sugars and disease risk. This review describes the development and applications of a biomarker of sugars intake, informs its future use and recommends directions for future research. Recently, 24 h urinary sucrose and fructose were suggested as a predictive biomarker for total sugars intake, based on findings from three highly controlled feeding studies conducted in the United Kingdom. From this work, a calibration equation for the biomarker that provides an unbiased measure of sugars intake was generated that has since been used in two US-based studies with free-living individuals to assess measurement error in dietary self-reports and to develop regression calibration equations that could be used in future diet-disease analyses. Further applications of the biomarker include its use as a surrogate measure of intake in diet-disease association studies. Although this biomarker has great potential and exhibits favorable characteristics, available data come from a few controlled studies with limited sample sizes conducted in the UK. Larger feeding studies conducted in different populations are needed to further explore biomarker characteristics and stability of its biases, compare its performance, and generate a unique, or population-specific biomarker calibration equations to be applied in future studies. A validated sugars biomarker is critical for informed interpretation of sugars-disease association studies. PMID:26184307

  11. Multi-Objective Flight Control for Drag Minimization and Load Alleviation of High-Aspect Ratio Flexible Wing Aircraft

    NASA Technical Reports Server (NTRS)

    Nguyen, Nhan; Ting, Eric; Chaparro, Daniel; Drew, Michael; Swei, Sean

    2017-01-01

    As aircraft wings become much more flexible due to the use of light-weight composites material, adverse aerodynamics at off-design performance can result from changes in wing shapes due to aeroelastic deflections. Increased drag, hence increased fuel burn, is a potential consequence. Without means for aeroelastic compensation, the benefit of weight reduction from the use of light-weight material could be offset by less optimal aerodynamic performance at off-design flight conditions. Performance Adaptive Aeroelastic Wing (PAAW) technology can potentially address these technical challenges for future flexible wing transports. PAAW technology leverages multi-disciplinary solutions to maximize the aerodynamic performance payoff of future adaptive wing design, while addressing simultaneously operational constraints that can prevent the optimal aerodynamic performance from being realized. These operational constraints include reduced flutter margins, increased airframe responses to gust and maneuver loads, pilot handling qualities, and ride qualities. All of these constraints while seeking the optimal aerodynamic performance present themselves as a multi-objective flight control problem. The paper presents a multi-objective flight control approach based on a drag-cognizant optimal control method. A concept of virtual control, which was previously introduced, is implemented to address the pair-wise flap motion constraints imposed by the elastomer material. This method is shown to be able to satisfy the constraints. Real-time drag minimization control is considered to be an important consideration for PAAW technology. Drag minimization control has many technical challenges such as sensing and control. An initial outline of a real-time drag minimization control has already been developed and will be further investigated in the future. A simulation study of a multi-objective flight control for a flight path angle command with aeroelastic mode suppression and drag minimization demonstrates the effectiveness of the proposed solution. In-flight structural loads are also an important consideration. As wing flexibility increases, maneuver load and gust load responses can be significant and therefore can pose safety and flight control concerns. In this paper, we will extend the multi-objective flight control framework to include load alleviation control. The study will focus initially on maneuver load minimization control, and then subsequently will address gust load alleviation control in future work.

  12. PTSD symptoms and sexual harassment: the role of attributions and perceived control.

    PubMed

    Larsen, Sadie E; Fitzgerald, Louise F

    2011-09-01

    Researchers have compiled significant evidence demonstrating that sexual harassment leads to psychological harm, including the full symptom picture of PTSD, but few have examined the psychological processes involved. Research on attributions among trauma victims would suggest that causal attributions and perceptions of control may be important predictors of outcomes. The authors discuss a study involving a path model that used data from 189 women involved in sexual harassment litigation. Results indicate that both self-blame and harasser blame were positively related to PTSD symptoms. Control over recovery and the perception that future harassment is unlikely were both related to fewer PTSD symptoms. Unexpectedly, perceived control over future harassment is related to higher levels of PTSD symptoms. Implications for research and practice are discussed.

  13. NASA Innovation Fund 2010 Project Elastically Shaped Future Air Vehicle Concept

    NASA Technical Reports Server (NTRS)

    Nguyen, Nhan

    2010-01-01

    This report describes a study conducted in 2010 under the NASA Innovation Fund Award to develop innovative future air vehicle concepts. Aerodynamic optimization was performed to produce three different aircraft configuration concepts for low drag, namely drooped wing, inflected wing, and squashed fuselage. A novel wing shaping control concept is introduced. This concept describes a new capability of actively controlling wing shape in-flight to minimize drag. In addition, a novel flight control effector concept is developed to enable wing shaping control. This concept is called a variable camber continuous trailing edge flap that can reduce drag by as much as 50% over a conventional flap. In totality, the potential benefits of fuel savings offered by these concepts can be significant.

  14. Large scale systems : a study of computer organizations for air traffic control applications.

    DOT National Transportation Integrated Search

    1971-06-01

    Based on current sizing estimates and tracking algorithms, some computer organizations applicable to future air traffic control computing systems are described and assessed. Hardware and software problem areas are defined and solutions are outlined.

  15. Preliminary evidence of altered neural response during intertemporal choice of losses in adult attention-deficit hyperactivity disorder.

    PubMed

    Tanaka, Saori C; Yahata, Noriaki; Todokoro, Ayako; Kawakubo, Yuki; Kano, Yukiko; Nishimura, Yukika; Ishii-Takahashi, Ayaka; Ohtake, Fumio; Kasai, Kiyoto

    2018-04-30

    Impulsive behaviours are common symptoms of attention-deficit hyperactivity disorder (ADHD). Although previous studies have suggested functional models of impulsive behaviour, a full explanation of impulsivity in ADHD remains elusive. To investigate the detailed mechanisms behind impulsive behaviour in ADHD, we applied an economic intertemporal choice task involving gains and losses to adults with ADHD and healthy controls and measured brain activity by functional magnetic resonance imaging. In the intertemporal choice of future gains, we observed no behavioural or neural difference between the two groups. In the intertemporal choice of future losses, adults with ADHD exhibited higher discount rates than the control participants. Furthermore, a comparison of brain activity representing the sensitivity of future loss in the two groups revealed significantly lower activity in the striatum and higher activity in the amygdala in adults with ADHD than in controls. Our preliminary findings suggest that an altered size sensitivity to future loss is involved in apparent impulsive choice behaviour in adults with ADHD and shed light on the multifaceted impulsivity underlying ADHD.

  16. The Relationship Between Stressful Life Events, Locus of Control, and Suicidal Ideation.

    ERIC Educational Resources Information Center

    Crepeau, James J.

    Numerous studies involving suicide attempters and those who commit suicide suggest that the suicidal individual perceives limited control over the environment, the occurrence of stressful life events and a diminished probability of future success. Results of the present study indicate a relationship between the frequency of suicidal thoughts among…

  17. Making Decisions about Now and Later: Development of Future-Oriented Self-Control

    ERIC Educational Resources Information Center

    Garon, Nancy M.; Longard, Julie; Bryson, Susan E.; Moore, Chris

    2012-01-01

    This study explored factors underlying preschoolers' ability to make future-oriented choices. In a delay-of-gratification choice task, quantity and visibility of the reward was systematically varied. Participants included 90 typically developing children aged 2-4 years. Children made more choices to delay gratification as the quantity of the…

  18. Pilot evaluation of a media literacy program for tobacco prevention targeting early adolescents shows mixed results.

    PubMed

    Kaestle, Christine E; Chen, Yvonnes; Estabrooks, Paul A; Zoellner, Jamie; Bigby, Brandon

    2013-01-01

    The purpose of this pilot study was to assess the impact of media literacy for tobacco prevention for youth delivered through a community site. A randomized pretest-posttest evaluation design with matched-contact treatment and control conditions. The pilot study was delivered through the YMCA in a lower-income suburban and rural area of Southwest Virginia, a region long tied, both economically and culturally, to the tobacco industry. Children ages 8 to 14 (76% white, 58% female) participated in the study (n = 38). The intervention was an antismoking media literacy program (five 1-hour lessons) compared with a matched-contact creative writing control program. General media literacy, three domains of tobacco-specific media literacy ("authors and audiences," "messages and meanings," and "representation and reality"), tobacco attitudes, and future expectations were assessed. Multiple regression modeling assessed the impact of the intervention, controlling for pretest measures, age, and sex. General media literacy and tobacco-specific "authors and audiences" media literacy improved significantly for treatment compared with control (p < .05); results for other tobacco-specific media literacy measures and for tobacco attitudes were not significant. Future expectations of smoking increased significantly for treatment participants ages 10 and younger (p < .05). Mixed results indicated that improvements in media literacy are accompanied by an increase in future expectations to smoke for younger children.

  19. Assessment Study on Sensors and Automation in the Industries of the Future. Reports on Industrial Controls, Information Processing, Automation, and Robotics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bennett, Bonnie; Boddy, Mark; Doyle, Frank

    This report presents the results of an expert study to identify research opportunities for Sensors & Automation, a sub-program of the U.S. Department of Energy (DOE) Industrial Technologies Program (ITP). The research opportunities are prioritized by realizable energy savings. The study encompasses the technology areas of industrial controls, information processing, automation, and robotics. These areas have been central areas of focus of many Industries of the Future (IOF) technology roadmaps. This report identifies opportunities for energy savings as a direct result of advances in these areas and also recognizes indirect means of achieving energy savings, such as product quality improvement,more » productivity improvement, and reduction of recycle.« less

  20. Success evaluation of the biological control of Fusarium wilts of cucumber, banana, and tomato since 2000 and future research strategies.

    PubMed

    Raza, Waseem; Ling, Ning; Zhang, Ruifu; Huang, Qiwei; Xu, Yangchun; Shen, Qirong

    2017-03-01

    The Fusarium wilt caused by Fusarium oxysporum strains is the most devastating disease of cucumber, banana, and tomato. The biological control of this disease has become an attractive alternative to the chemical fungicides and other conventional control methods. In this review, the research trends and biological control efficiencies (BCE) of different microbial strains since 2000 are reviewed in detail, considering types of microbial genera, inoculum application methods, plant growth medium and conditions, inoculum application with amendments, and co-inoculation of different microbial strains and how those affect the BCE of Fusarium wilt. The data evaluation showed that the BCE of biocontrol agents was higher against the Fusarium wilt of cucumber compared to the Fusarium wilts of banana and tomato. Several biocontrol agents mainly Bacillus, Trichoderma, Pseudomonas, nonpathogenic Fusarium, and Penicillium strains were evaluated to control Fusarium wilt, but still this lethal disease could not be controlled completely. We have discussed different reasons of inconsistent results and recommendations for the betterment of BCE in the future. This review provides knowledge of the biotechnology of biological control of Fusarium wilt of cucumber, banana, and tomato in a nut shell that will provide researchers a beginning line to start and to organize and plan research for the future studies.

  1. Underwater acoustic wireless sensor networks: advances and future trends in physical, MAC and routing layers.

    PubMed

    Climent, Salvador; Sanchez, Antonio; Capella, Juan Vicente; Meratnia, Nirvana; Serrano, Juan Jose

    2014-01-06

    This survey aims to provide a comprehensive overview of the current research on underwater wireless sensor networks, focusing on the lower layers of the communication stack, and envisions future trends and challenges. It analyzes the current state-of-the-art on the physical, medium access control and routing layers. It summarizes their security threads and surveys the currently proposed studies. Current envisioned niches for further advances in underwater networks research range from efficient, low-power algorithms and modulations to intelligent, energy-aware routing and medium access control protocols.

  2. Impact of choice of future climate change projection on growth chamber experimental outcomes: a preliminary study in potato.

    PubMed

    Leisner, Courtney P; Wood, Joshua C; Vaillancourt, Brieanne; Tang, Ying; Douches, Dave S; Robin Buell, C; Winkler, Julie A

    2018-04-01

    Understanding the impacts of climate change on agriculture is essential to ensure adequate future food production. Controlled growth experiments provide an effective tool for assessing the complex effects of climate change. However, a review of the use of climate projections in 57 previously published controlled growth studies found that none considered within-season variations in projected future temperature change, and few considered regional differences in future warming. A fixed, often arbitrary, temperature perturbation typically was applied for the entire growing season. This study investigates the utility of employing more complex climate change scenarios in growth chamber experiments. A case study in potato was performed using three dynamically downscaled climate change projections for the mid-twenty-first century that differ in terms of the timing during the growing season of the largest projected temperature changes. The climate projections were used in growth chamber experiments for four elite potato cultivars commonly planted in Michigan's major potato growing region. The choice of climate projection had a significant influence on the sign and magnitude of the projected changes in aboveground biomass and total tuber count, whereas all projections suggested an increase in total tuber weight and a decrease in specific gravity, a key market quality trait for potato, by mid-century. These results demonstrate that the use of more complex climate projections that extend beyond a simple incremental change can provide additional insights into the future impacts of climate change on crop production and the accompanying uncertainty.

  3. 17 CFR 21.01 - Special calls for information on controlled accounts from futures commission merchants, clearing...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CALLS § 21.01 Special calls for information on controlled accounts from futures commission merchants... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Special calls for information on controlled accounts from futures commission merchants, clearing members and introducing brokers...

  4. Energy and Economic Trade Offs for Advanced Technology Subsonic Aircraft

    NASA Technical Reports Server (NTRS)

    Maddalon, D. V.; Wagner, R. D.

    1976-01-01

    Changes in future aircraft technology which conserve energy are studied, along with the effect of these changes on economic performance. Among the new technologies considered are laminar-flow control, composite materials with and without laminar-flow control, and advanced airfoils. Aircraft design features studied include high-aspect-ratio wings, thickness ratio, and range. Engine technology is held constant at the JT9D level. It is concluded that wing aspect ratios of future aircraft are likely to significantly increase as a result of new technology and the push of higher fuel prices. Composite materials may raise aspect radio to about 11 to 12 and practical laminar flow-control systems may further increase aspect ratio to 14 or more. Advanced technology provides significant reductions in aircraft take-off gross weight, energy consumption, and direct operating cost.

  5. Is ambiguity tolerance malleable? Experimental evidence with potential implications for future research.

    PubMed

    Endres, Megan L; Camp, Richaurd; Milner, Morgan

    2015-01-01

    We conducted two research studies to address the malleability of tolerance of ambiguity (TA) by manipulating situational ambiguity. Students participated in a semester-end assessment of their management skills (n = 306). In Study 1, students in low and moderate ambiguity conditions had significantly higher post-experiment TA, more positive change in self-efficacy, and marginally higher faculty ratings. In Study 2, a control group (n = 103) did not participate in the assessment and was established for comparison to the first study results. The Study 2 students reported TA significantly lower than Study 1 students in the low and moderate ambiguity conditions. The control group TA was not significantly different from that of the Study 1 high ambiguity condition. This further suggested TA's situational malleability, as those who had controlled access to structured information appeared to have increased their TA over that observed in the other two groups. These results suggest that TA may be malleable. We review the relevant literature, offer hypotheses, report our analyses and findings, and then propose future research, and potential prescriptive applications in such areas as management development, assessment, and decision-making.

  6. Future decision-making without episodic mental time travel.

    PubMed

    Kwan, Donna; Craver, Carl F; Green, Leonard; Myerson, Joel; Boyer, Pascal; Rosenbaum, R Shayna

    2012-06-01

    Deficits in episodic memory are associated with deficits in the ability to imagine future experiences (i.e., mental time travel). We show that K.C., a person with episodic amnesia and an inability to imagine future experiences, nonetheless systematically discounts the value of future rewards, and his discounting is within the range of controls in terms of both rate and consistency. Because K.C. is neither able to imagine personal uses for the rewards nor provide a rationale for selecting larger future rewards over smaller current rewards, this study demonstrates a dissociation between imagining and making decisions involving the future. Thus, although those capable of mental time travel may use it in making decisions about future rewards, these results demonstrate that it is not required for such decisions. Copyright © 2011 Wiley Periodicals, Inc.

  7. Control Strategy Tool (CoST)

    EPA Pesticide Factsheets

    The EPA Control Strategy Tool (CoST) is a software tool for projecting potential future control scenarios, their effects on emissions and estimated costs. This tool uses the NEI and the Control Measures Dataset as key inputs. CoST outputs are projections of future control scenarios.

  8. R&D control study : plan for future jet fuel distribution quality control and description of fuel properties catalog

    DOT National Transportation Integrated Search

    2014-05-09

    The Broad Agency Announcement Alternative Aviation Fuels was a solicitation released by the U.S. Department of Transportation Research and Innovative Technology Administration (RITA) / John A. Volpe National Transportation Systems Center with funding...

  9. Age differences in future orientation and delay discounting.

    PubMed

    Steinberg, Laurence; Graham, Sandra; O'Brien, Lia; Woolard, Jennifer; Cauffman, Elizabeth; Banich, Marie

    2009-01-01

    Age differences in future orientation are examined in a sample of 935 individuals between 10 and 30 years using a delay discounting task as well as a new self-report measure. Younger adolescents consistently demonstrate a weaker orientation to the future than do individuals aged 16 and older, as reflected in their greater willingness to accept a smaller reward delivered sooner than a larger one that is delayed, and in their characterizations of themselves as less concerned about the future and less likely to anticipate the consequences of their decisions. Planning ahead, in contrast, continues to develop into young adulthood. Future studies should distinguish between future orientation and impulse control, which may have different neural underpinnings and follow different developmental timetables.

  10. Different involvement of medial prefrontal cortex and dorso-lateral striatum in automatic and controlled processing of a future conditioned stimulus.

    PubMed

    Pérez-Díaz, Francisco; Díaz, Estrella; Sánchez, Natividad; Vargas, Juan Pedro; Pearce, John M; López, Juan Carlos

    2017-01-01

    Recent studies support the idea that stimulus processing in latent inhibition can vary during the course of preexposure. Controlled attentional mechanisms are said to be important in the early stages of preexposure, while in later stages animals adopt automatic processing of the stimulus to be used for conditioning. Given this distinction, it is possible that both types of processing are governed by different neural systems, affecting differentially the retrieval of information about the stimulus. In the present study we tested if a lesion to the dorso-lateral striatum or to the medial prefrontal cortex has a selective effect on exposure to the future conditioned stimulus (CS). With this aim, animals received different amounts of exposure to the future CS. The results showed that a lesion to the medial prefrontal cortex enhanced latent inhibition in animals receiving limited preexposure to the CS, but had no effect in animals receiving extended preexposure to the CS. The lesion of the dorso-lateral striatum produced a decrease in latent inhibition, but only in animals with an extended exposure to the future conditioned stimulus. These results suggest that the dorsal striatum and medial prefrontal cortex play essential roles in controlled and automatic processes. Automatic attentional processes appear to be impaired by a lesion to the dorso-lateral striatum and facilitated by a lesion to the prefrontal cortex.

  11. Different involvement of medial prefrontal cortex and dorso-lateral striatum in automatic and controlled processing of a future conditioned stimulus

    PubMed Central

    Pérez-Díaz, Francisco; Díaz, Estrella; Sánchez, Natividad; Vargas, Juan Pedro; Pearce, John M.

    2017-01-01

    Recent studies support the idea that stimulus processing in latent inhibition can vary during the course of preexposure. Controlled attentional mechanisms are said to be important in the early stages of preexposure, while in later stages animals adopt automatic processing of the stimulus to be used for conditioning. Given this distinction, it is possible that both types of processing are governed by different neural systems, affecting differentially the retrieval of information about the stimulus. In the present study we tested if a lesion to the dorso-lateral striatum or to the medial prefrontal cortex has a selective effect on exposure to the future conditioned stimulus (CS). With this aim, animals received different amounts of exposure to the future CS. The results showed that a lesion to the medial prefrontal cortex enhanced latent inhibition in animals receiving limited preexposure to the CS, but had no effect in animals receiving extended preexposure to the CS. The lesion of the dorso-lateral striatum produced a decrease in latent inhibition, but only in animals with an extended exposure to the future conditioned stimulus. These results suggest that the dorsal striatum and medial prefrontal cortex play essential roles in controlled and automatic processes. Automatic attentional processes appear to be impaired by a lesion to the dorso-lateral striatum and facilitated by a lesion to the prefrontal cortex. PMID:29240804

  12. Comparative Pessimism or Optimism: Depressed Mood, Risk-Taking, Social Utility and Desirability.

    PubMed

    Milhabet, Isabelle; Le Barbenchon, Emmanuelle; Cambon, Laurent; Molina, Guylaine

    2015-03-05

    Comparative optimism can be defined as a self-serving, asymmetric judgment of the future. It is often thought to be beneficial and socially accepted, whereas comparative pessimism is correlated with depression and socially rejected. Our goal was to examine the social acceptance of comparative optimism and the social rejection of comparative pessimism in two dimensions of social judgment, social desirability and social utility, considering the attributions of dysphoria and risk-taking potential (studies 2 and 3) on outlooks on the future. In three experiments, the participants assessed either one (study 1) or several (studies 2 and 3) fictional targets in two dimensions, social utility and social desirability. Targets exhibiting comparatively optimistic or pessimistic outlooks on the future were presented as non-depressed, depressed, or neither (control condition) (study 1); non-depressed or depressed (study 2); and non-depressed or in control condition (study 3). Two significant results were obtained: (1) social rejection of comparative pessimism in the social desirability dimension, which can be explained by its depressive feature; and (2) comparative optimism was socially accepted on the social utility dimension, which can be explained by the perception that comparatively optimistic individuals are potential risk-takers.

  13. Control, Motivation, Affect, and Strategic Self-Regulation in the College Classroom: A Multidimensional Phenomenon

    ERIC Educational Resources Information Center

    Shell, Duane F.; Husman, Jenefer

    2008-01-01

    This study of 397 undergraduate students examined relations between self-reported control, goal orientation, future time perspective, affect, and strategic self-regulation. Five patterns were found in three canonical dimensions. The high end of bipolar Dimension 1 linked high self-regulated strategy use and study effort to high self-efficacy,…

  14. Future Time Perspective and Motivational Categories in Argentinean Adolescents

    ERIC Educational Resources Information Center

    Vazquez, Stella Maris; Rapetti, Maria Virginia

    2006-01-01

    This study is based on a sample of 332 Argentinean teenagers in their last year of secondary school. In the context of the relational theory of motivation, an attempt is made to determine the motivational categories best predicting Future Time Perspective (FTP) extension. The influence of the sex, locus of control, social class, and school ethos…

  15. Protocol for systematic review of evidence on the determinants and influence of early glycaemic control in childhood-onset type 1 diabetes.

    PubMed

    Mazarello Paes, Veena; Charalampopoulos, Dimitrios; Khanolkar, Amal R; Taylor-Robinson, David; Viner, Russell; Edge, Julie; Stephenson, Terence; Amin, Rakesh

    2015-11-12

    Landmark studies in adult-onset type 1 diabetes (T1D) populations indicate that improved glycaemic control through use of intensive insulin therapy is strongly associated with reduced risk for the development of diabetes-related complications and mortality in later years. However, it is unclear whether these associations can be extrapolated to childhood-onset T1D, given the influence of other important biological and psychosocial determinants of glycaemic control, particularly during adolescence. The aims of the review are (1) to investigate the impact of early glycaemic control (within the first 2 years after diagnosis) on subsequent glycaemic trends and risk of complications during the life course of childhood-onset T1D and (2) to identify the predictors of early glycaemic control in children and young people (0-25 years). The methods used in this study are systematic identification, review and mapping of quantitative (intervention and observational) and qualitative literature; assessing the effect and predictors of early glycaemic control in T1D (diagnosed ≤18 years) on risk or prevalence of later complications. An iterated search strategy, with no language or period restrictions, was applied to identify studies from six electronic databases. This will be supplemented by hand-searching (reference lists and contacting authors of studies meeting the inclusion criteria). Studies assessing glycaemic control within the first 2 years of diagnosis in children (at baseline) will be quality-assessed against predefined criteria and mapped descriptively to future health outcomes. Extracted data will be analysed and synthesised using narrative and forest plots or harvest plots for quantitative evidence and thematic analyses for qualitative studies. To get a deeper understanding of the predictors of early glycaemic control in reducing complications in childhood and adult life, we will integrate qualitative and quantitative evidence using mixed methods or parallel synthesis approach. These linked reviews will be the first to systematically investigate the effects of early glycaemic control and integrate both the quantitative and qualitative evidence on predictors of early glycaemic control in childhood-onset T1D in reducing future diabetes complications. This will help identify and map current research and inform development of effective future interventions. PROSPERO CRD42015024546.

  16. Future orientation, school contexts, and problem behaviors: a multilevel study.

    PubMed

    Chen, Pan; Vazsonyi, Alexander T

    2013-01-01

    The association between future orientation and problem behaviors has received extensive empirical attention; however, previous work has not considered school contextual influences on this link. Using a sample of N = 9,163 9th to 12th graders (51.0 % females) from N = 85 high schools of the National Longitudinal Study of Adolescent Health, the present study examined the independent and interactive effects of adolescent future orientation and school contexts (school size, school location, school SES, school future orientation climate) on problem behaviors. Results provided evidence that adolescent future orientation was associated independently and negatively with problem behaviors. In addition, adolescents from large-size schools reported higher levels of problem behaviors than their age mates from small-size schools, controlling for individual-level covariates. Furthermore, an interaction effect between adolescent future orientation and school future orientation climate was found, suggesting influences of school future orientation climate on the link between adolescent future orientation and problem behaviors as well as variations in effects of school future orientation climate across different levels of adolescent future orientation. Specifically, the negative association between adolescent future orientation and problem behaviors was stronger at schools with a more positive climate of future orientation, whereas school future orientation climate had a significant and unexpectedly positive relationship with problem behaviors for adolescents with low levels of future orientation. Findings implicate the importance of comparing how the future orientation-problem behaviors link varies across different ecological contexts and the need to understand influences of school climate on problem behaviors in light of differences in psychological processes among adolescents.

  17. Head Trauma with or without Mild Brain Injury Increases the Risk of Future Traumatic Death: A Controlled Prospective 15-Year Follow-Up Study.

    PubMed

    Vaaramo, Kalle; Puljula, Jussi; Tetri, Sami; Juvela, Seppo; Hillbom, Matti

    2015-10-15

    Patients who have recovered from traumatic brain injury (TBI) show an increased risk of premature death. To investigate long-term mortality rates in a population admitted to the hospital for head injury (HI), we conducted a population-based prospective case-control, record-linkage study, All subjects who were living in Northern Ostrobothnia, and who were admitted to Oulu University Hospital in 1999 because of HI (n=737), and 2196 controls matched by age, gender, and residence randomly drawn from the population of Northern Ostrobothnia were included. Death rate and causes of death in HI subjects during 15 years of follow-up was compared with the general population controls. The crude mortality rates were 56.9, 18.6, and 23.8% for subjects having moderate-to-severe traumatic brain injury (TBI), mild TBI, and head injury without TBI, respectively. The corresponding approximate annual mortality rates were 6.7%, 1.4%, and 1.9%. All types of index HI predicted a significant risk of traumatic death in the future. Subjects who had HI without TBI had an increased risk of both death from all causes (hazard ratio 2.00; 95% confidence interval 1.57-2.55) and intentional or unintentional traumatic death (4.01, 2.20-7.30), compared with controls. The main founding was that even HI without TBI carries an increased risk of future traumatic death. The reason for this remains unknown and further studies are needed. To prevent such premature deaths, post-traumatic therapy should include an interview focusing on lifestyle factors.

  18. Tobacco control advocacy in the age of social media: using Facebook, Twitter and change.

    PubMed

    Hefler, Marita; Freeman, Becky; Chapman, Simon

    2013-05-01

    The tobacco industry's use of social media sites, such as Facebook, is an emerging area of research; however, this is the first study of the potential for social media to advance tobacco control. This paper presents three case studies of using social media for tobacco control advocacy, demonstrates how social media can facilitate direct and effective action, and provides tools and lessons learned for future campaigns.

  19. Understanding the metabolic and health effects of low-calorie sweeteners: methodological considerations and implications for future research

    PubMed Central

    Sylvetsky, Allison C.; Blau, Jenny E.; Rother, Kristina I.

    2016-01-01

    Consumption of foods, beverages, and packets containing low-calorie sweeteners (LCS) has increased markedly across gender, age, race/ethnicity, weight status, and socioeconomic subgroups. However, well-controlled intervention studies rigorously evaluating the health effects of LCS in humans are limited. One of the key questions is whether LCS are indeed a beneficial strategy for weight management and prevention of obesity. The current review discusses several methodological considerations in the design and interpretation of these studies. Specifically, we focus on the selection of study participants, inclusion of an appropriate control, importance of considering habitual LCS exposure, selection of specific LCS, dose and route of LCS administration, choice of study outcomes, and the context and generalizability of the study findings. These critical considerations will guide the design of future studies and thus assist in understanding the health effects of LCS. PMID:26936185

  20. Understanding the metabolic and health effects of low-calorie sweeteners: methodological considerations and implications for future research.

    PubMed

    Sylvetsky, Allison C; Blau, Jenny E; Rother, Kristina I

    2016-06-01

    Consumption of foods, beverages, and packets containing low-calorie sweeteners (LCS) has increased markedly across gender, age, race/ethnicity, weight status, and socio-economic subgroups. However, well-controlled intervention studies rigorously evaluating the health effects of LCS in humans are limited. One of the key questions is whether LCS are indeed a beneficial strategy for weight management and prevention of obesity. The current review discusses several methodological considerations in the design and interpretation of these studies. Specifically, we focus on the selection of study participants, inclusion of an appropriate control, importance of considering habitual LCS exposure, selection of specific LCS, dose and route of LCS administration, choice of study outcomes, and the context and generalizability of the study findings. These critical considerations will guide the design of future studies and thus assist in understanding the health effects of LCS.

  1. Performance of air traffic control specialists (ATCS'S) on a laboratory radar monitoring task : an exploratory study of complacency and a comparison of ATCS and non-ATCS performance.

    DOT National Transportation Integrated Search

    1982-04-01

    The role of the air traffic control specialist (ATCS) is proposed highly automated air traffic systems of the future is currently receiving considerable attention. At the present time, a prevalent conception of the controller's role in such systems i...

  2. 77 FR 43967 - Account Ownership and Control Report; Withdrawal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-26

    ... 15, 16, 17, et al. Account Ownership and Control Report; Withdrawal; Ownership and Control Reports... RIN 3038-AC63 Account Ownership and Control Report; Withdrawal AGENCY: Commodity Futures Trading... ownership and control information for all trading accounts active on U.S. futures exchanges and other...

  3. The Segmented Aperture Interferometric Nulling Testbed (SAINT) I: Overview and Air-side System Description

    NASA Technical Reports Server (NTRS)

    Hicks, Brian A.; Lyon, Richard G.; Petrone, Peter, III; Bolcar, Matthew R.; Bolognese, Jeff; Clampin, Mark; Dogoda, Peter; Dworzanski, Daniel; Helmbrecht, Michael A.; Koca, Corina; hide

    2016-01-01

    This work presents an overview of the This work presents an overview of the Segmented Aperture Interferometric Nulling Testbed (SAINT), a project that will pair an actively-controlled macro-scale segmented mirror with the Visible Nulling Coronagraph (VNC). SAINT will incorporate the VNCs demonstrated wavefront sensing and control system to refine and quantify the end-to-end system performance for high-contrast starlight suppression. This pathfinder system will be used as a tool to study and refine approaches to mitigating instabilities and complex diffraction expected from future large segmented aperture telescopes., a project that will pair an actively-controlled macro-scale segmented mirror with the Visible Nulling Coronagraph (VNC). SAINT will incorporate the VNCs demonstrated wavefront sensing and control system to refine and quantify the end-to-end system performance for high-contrast starlight suppression. This pathfinder system will be used as a tool to study and refine approaches to mitigating instabilities and complex diffraction expected from future large segmented aperture telescopes.

  4. Bayesian modeling of flexible cognitive control

    PubMed Central

    Jiang, Jiefeng; Heller, Katherine; Egner, Tobias

    2014-01-01

    “Cognitive control” describes endogenous guidance of behavior in situations where routine stimulus-response associations are suboptimal for achieving a desired goal. The computational and neural mechanisms underlying this capacity remain poorly understood. We examine recent advances stemming from the application of a Bayesian learner perspective that provides optimal prediction for control processes. In reviewing the application of Bayesian models to cognitive control, we note that an important limitation in current models is a lack of a plausible mechanism for the flexible adjustment of control over conflict levels changing at varying temporal scales. We then show that flexible cognitive control can be achieved by a Bayesian model with a volatility-driven learning mechanism that modulates dynamically the relative dependence on recent and remote experiences in its prediction of future control demand. We conclude that the emergent Bayesian perspective on computational mechanisms of cognitive control holds considerable promise, especially if future studies can identify neural substrates of the variables encoded by these models, and determine the nature (Bayesian or otherwise) of their neural implementation. PMID:24929218

  5. Enhancing self-efficacy improves episodic future thinking and social-decision making in combat veterans with posttraumatic stress disorder.

    PubMed

    Brown, Adam D; Kouri, Nicole A; Rahman, Nadia; Joscelyne, Amy; Bryant, Richard A; Marmar, Charles R

    2016-08-30

    Posttraumatic Stress Disorder (PTSD) is associated with maladaptive changes in self-identity, including impoverished perceived self-efficacy. This study examined if enhancing perceptions of self-efficacy in combat veterans with and without symptoms of PTSD promotes cognitive strategies associated with positive mental health outcomes. Prior to completing a future thinking and social problem-solving task, sixty-two OEF/OIF veterans with and without symptoms of PTSD were randomized to either a high self-efficacy (HSE) induction in which they were asked to recall three autobiographical memories demonstrating self-efficacy or a control condition in which they recalled any three autobiographical events. An interaction between HSE and PTSD revealed that individuals with symptoms of PTSD in the HSE condition generated future events with more self-efficacious statements than those with PTSD in the control condition, whereas those without PTSD did not differ in self-efficacy content across the conditions. In addition, individuals in the HSE condition exhibited better social problem solving than those in the control condition. Increasing perceptions of self-efficacy may promote future thinking and problem solving in ways that are relevant to overcoming trauma and adversity. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  6. Predicting Health Resilience in Pediatric Type 1 Diabetes: A Test of the Resilience Model Framework

    PubMed Central

    Huang, Bin; Pendley, Jennifer Shroff; Delamater, Alan; Dolan, Lawrence; Reeves, Grafton; Drotar, Dennis

    2015-01-01

    Objectives This research examined whether individual and family-level factors during the transition from late childhood to early adolescence protected individuals from an increased risk of poor glycemic control across time, which is a predictor of future diabetes-related complications (i.e., health resilience). Methods This longitudinal, multisite study included 239 patients with type 1 diabetes and their caregivers. Glycemic control was based on hemoglobin A1c. Individual and family-level factors included: demographic variables, youth behavioral regulation, adherence (frequency of blood glucose monitoring), diabetes self-management, level of parental support for diabetes autonomy, level of youth mastery and responsibility for diabetes management, and diabetes-related family conflict. Results Longitudinal mixed-effects logistic regression indicated that testing blood glucose more frequently, better self-management, and less diabetes-related family conflict were indicators of health resilience. Conclusions Multiple individual and family-level factors predicted risk for future health complications. Future research should develop interventions targeting specific individual and family-level factors to sustain glycemic control within recommended targets, which reduces the risk of developing future health complications during the transition to adolescence and adulthood. PMID:26152400

  7. Working memory capacity does not always support future-oriented mind-wandering.

    PubMed

    McVay, Jennifer C; Unsworth, Nash; McMillan, Brittany D; Kane, Michael J

    2013-03-01

    To evaluate the claim that mind-wandering demands executive resources, and more specifically that people with better executive control will have the resources to engage in more future-oriented thought than will those with poorer executive control, we reanalyzed thought-report data from 2 independently conducted studies (J. C. McVay & M. J. Kane, 2012, Why does working memory capacity predict variation in reading comprehension? On the influence of mind wandering and executive attention, Journal of Experimental Psychology: General, Vol. 141, pp. 302-320; N. Unsworth & B. D. McMillan, in press, Mind-wandering and reading comprehension: Examining the roles of working memory capacity, interest, motivation, and topic experience, Journal of Experimental Psychology: Learning, Memory, and Cognition) on working memory capacity (WMC), mind-wandering, and reading comprehension. Both of these individual-differences studies assessed large samples of university subjects' WMC abilities via multiple tasks and probed their immediate thought content while reading; in reporting any task-unrelated thoughts (TUTs), subjects indicated whether those thoughts were about the future or the past, if applicable. In contrast to previously published findings indicating that higher WMC subjects mind-wandered about the future more than did lower WMC subjects (B. Baird, J. Smallwood, & J. W. Schooler, 2011, Back to the future: Autobiographical planning and the functionality of mind-wandering, Consciousness and Cognition, Vol. 20, pp. 1604-1611), we found only weak to modest negative correlations between WMC and future-oriented TUTs. If anything, our findings suggest that higher WMC subjects' TUTs were somewhat less often future-oriented than were lower WMC subjects'. Either WMC is not truly associated with mind-wandering about the future, or we have identified some important boundary conditions around that association.

  8. Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework

    PubMed Central

    Eldridge, Sandra M.; Lancaster, Gillian A.; Campbell, Michael J.; Thabane, Lehana; Hopewell, Sally; Coleman, Claire L.; Bond, Christine M.

    2016-01-01

    We describe a framework for defining pilot and feasibility studies focusing on studies conducted in preparation for a randomised controlled trial. To develop the framework, we undertook a Delphi survey; ran an open meeting at a trial methodology conference; conducted a review of definitions outside the health research context; consulted experts at an international consensus meeting; and reviewed 27 empirical pilot or feasibility studies. We initially adopted mutually exclusive definitions of pilot and feasibility studies. However, some Delphi survey respondents and the majority of open meeting attendees disagreed with the idea of mutually exclusive definitions. Their viewpoint was supported by definitions outside the health research context, the use of the terms ‘pilot’ and ‘feasibility’ in the literature, and participants at the international consensus meeting. In our framework, pilot studies are a subset of feasibility studies, rather than the two being mutually exclusive. A feasibility study asks whether something can be done, should we proceed with it, and if so, how. A pilot study asks the same questions but also has a specific design feature: in a pilot study a future study, or part of a future study, is conducted on a smaller scale. We suggest that to facilitate their identification, these studies should be clearly identified using the terms ‘feasibility’ or ‘pilot’ as appropriate. This should include feasibility studies that are largely qualitative; we found these difficult to identify in electronic searches because researchers rarely used the term ‘feasibility’ in the title or abstract of such studies. Investigators should also report appropriate objectives and methods related to feasibility; and give clear confirmation that their study is in preparation for a future randomised controlled trial designed to assess the effect of an intervention. PMID:26978655

  9. Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework.

    PubMed

    Eldridge, Sandra M; Lancaster, Gillian A; Campbell, Michael J; Thabane, Lehana; Hopewell, Sally; Coleman, Claire L; Bond, Christine M

    2016-01-01

    We describe a framework for defining pilot and feasibility studies focusing on studies conducted in preparation for a randomised controlled trial. To develop the framework, we undertook a Delphi survey; ran an open meeting at a trial methodology conference; conducted a review of definitions outside the health research context; consulted experts at an international consensus meeting; and reviewed 27 empirical pilot or feasibility studies. We initially adopted mutually exclusive definitions of pilot and feasibility studies. However, some Delphi survey respondents and the majority of open meeting attendees disagreed with the idea of mutually exclusive definitions. Their viewpoint was supported by definitions outside the health research context, the use of the terms 'pilot' and 'feasibility' in the literature, and participants at the international consensus meeting. In our framework, pilot studies are a subset of feasibility studies, rather than the two being mutually exclusive. A feasibility study asks whether something can be done, should we proceed with it, and if so, how. A pilot study asks the same questions but also has a specific design feature: in a pilot study a future study, or part of a future study, is conducted on a smaller scale. We suggest that to facilitate their identification, these studies should be clearly identified using the terms 'feasibility' or 'pilot' as appropriate. This should include feasibility studies that are largely qualitative; we found these difficult to identify in electronic searches because researchers rarely used the term 'feasibility' in the title or abstract of such studies. Investigators should also report appropriate objectives and methods related to feasibility; and give clear confirmation that their study is in preparation for a future randomised controlled trial designed to assess the effect of an intervention.

  10. Unmanned Aircraft System Control and ATC Communications Bandwidth Requirements

    NASA Technical Reports Server (NTRS)

    Henriksen, Steve

    2008-01-01

    There are significant activities taking place to establish the procedures and requirements for safe and routine operation of unmanned aircraft systems (UAS) in the National Airspace System (NAS). Among the barriers to overcome in achieving this goal is the lack of sufficient frequency spectrum necessary for the UAS control and air traffic control (ATC) communications links. This shortcoming is compounded by the fact that the UAS control communications links will likely be required to operate in protected frequency spectrum, just as ATC communications links are, because they relate to "safety and regularity of flight." To support future International Telecommunications Union (ITU) World Radio Conference (WRC) agenda items concerning new frequency allocations for UAS communications links, and to augment the Future Communications Study (FCS) Technology Evaluation Group efforts, NASA Glenn Research Center has sponsored a task to estimate the UAS control and ATC communications bandwidth requirements for safe, reliable, and routine operation of UAS in the NAS. This report describes the process and results of that task. The study focused on long-term bandwidth requirements for UAS approximately through 2030.

  11. Predictors of responses to stress among families coping with poverty-related stress.

    PubMed

    Santiago, Catherine DeCarlo; Etter, Erica Moran; Wadsworth, Martha E; Raviv, Tali

    2012-05-01

    This study tested how poverty-related stress (PRS), psychological distress, and responses to stress predicted future effortful coping and involuntary stress responses one year later. In addition, we explored age, sex, ethnicity, and parental influences on responses to stress over time. Hierarchical linear modeling analyses conducted with 98 low-income families (300 family members: 136 adults, 82 school-aged children, 82 adolescents) revealed that primary control coping, secondary control coping, disengagement, involuntary engagement, and involuntary disengagement each significantly predicted future use of that response. Primary and secondary control coping also predicted less maladaptive future responses to stress, while involuntary responses to stress undermined the development of adaptive responding. Age, sex, and interactions among PRS and prior coping were also found to predict certain responses to stress. In addition, child subgroup analyses demonstrate the importance of parental modeling of coping and involuntary stress responses, and warmth/nurturance and monitoring practices. Results are discussed with regard to the implications for preventive interventions with families in poverty.

  12. Episodic future thinking reduces delay discounting and cigarette demand: an investigation of the good-subject effect.

    PubMed

    Stein, Jeffrey S; Tegge, Allison N; Turner, Jamie K; Bickel, Warren K

    2018-04-01

    Episodic future thinking (EFT), an intervention involving mental simulation of future events, has been shown to reduce both delay discounting and cigarette self-administration. In the present study, we extended these findings by showing that EFT in a web-based sample of smokers reduces delay discounting and intensity of demand for cigarettes (ad libitum consumption) in a hypothetical purchase task. No effect was observed on elasticity of demand (sensitivity to price) or cigarette craving. We also explored whether demand characteristics (specifically, the "good-subject" effect) might be responsible for observed effects. EFT participants were significantly better able than control participants to discern the experimental hypothesis. However, EFT participants were not better than controls at identifying whether they had been assigned to the experimental group and, likewise, showed no differences in attitudes about the experiment and experimenter. Importantly, effects of EFT on delay discounting and demand remained significant even when controlling for measures of demand characteristics, indicating that EFT's effects are independent of participants' perceptions about the experiment.

  13. Space Suit Thermal Dynamics

    NASA Technical Reports Server (NTRS)

    Campbell, Anthony B.; Nair, Satish S.; Miles, John B.; Iovine, John V.; Lin, Chin H.

    1998-01-01

    The present NASA space suit (the Shuttle EMU) is a self-contained environmental control system, providing life support, environmental protection, earth-like mobility, and communications. This study considers the thermal dynamics of the space suit as they relate to astronaut thermal comfort control. A detailed dynamic lumped capacitance thermal model of the present space suit is used to analyze the thermal dynamics of the suit with observations verified using experimental and flight data. Prior to using the model to define performance characteristics and limitations for the space suit, the model is first evaluated and improved. This evaluation includes determining the effect of various model parameters on model performance and quantifying various temperature prediction errors in terms of heat transfer and heat storage. The observations from this study are being utilized in two future design efforts, automatic thermal comfort control design for the present space suit and design of future space suit systems for Space Station, Lunar, and Martian missions.

  14. Two routes toward optimism: how agentic and communal themes in autobiographical memories guide optimism for the future.

    PubMed

    Austin, Adrienne; Costabile, Kristi

    2017-11-01

    Autobiographical memories are particularly adaptive because they function not only to preserve the past, but also to direct our future thoughts and behaviours. Two studies were conducted to examine how communal and agentic themes of positive autobiographical memories differentially predicted the route from autobiographical memories to optimism for the future. Across two studies, results revealed that the degree to which participants focused on communal themes in their autobiographical memories predicted their experience of nostalgia. In turn, the experience of nostalgia increased participants' levels of self-esteem and in turn, optimism for the future. By contrast, the degree to which participants focused on agentic themes in their memories predicted self-esteem and optimism, operating outside the experience of nostalgia. These effects remained even after controlling for self-focused attention. Together, these studies provide greater understanding of the interrelations among autobiographical memory, self-concept, and time, and demonstrate how agency and communion operate to influence perceptions of one's future when thinking about the past.

  15. Underwater Acoustic Wireless Sensor Networks: Advances and Future Trends in Physical, MAC and Routing Layers

    PubMed Central

    Climent, Salvador; Sanchez, Antonio; Capella, Juan Vicente; Meratnia, Nirvana; Serrano, Juan Jose

    2014-01-01

    This survey aims to provide a comprehensive overview of the current research on underwater wireless sensor networks, focusing on the lower layers of the communication stack, and envisions future trends and challenges. It analyzes the current state-of-the-art on the physical, medium access control and routing layers. It summarizes their security threads and surveys the currently proposed studies. Current envisioned niches for further advances in underwater networks research range from efficient, low-power algorithms and modulations to intelligent, energy-aware routing and medium access control protocols. PMID:24399155

  16. The Development of Future Orientation is Associated with Faster Decline in Hopelessness during Adolescence.

    PubMed

    Mac Giollabhui, Naoise; Nielsen, Johanna; Seidman, Sam; Olino, Thomas M; Abramson, Lyn Y; Alloy, Lauren B

    2018-01-05

    Hopelessness is implicated in multiple psychological disorders. Little is known, however, about the trajectory of hopelessness during adolescence or how emergent future orientation may influence its trajectory. Parallel process latent growth curve modelling tested whether (i) trajectories of future orientation and hopelessness and (ii) within-individual change in future orientation and hopelessness were related. The study was comprised of 472 adolescents [52% female, 47% Caucasian, 47% received free lunch] recruited at ages 12-13 who completed measures of future orientation and hopelessness at five annual assessments. The results indicate that a general decline in hopelessness across adolescence occurs quicker for those experiencing faster development of future orientation, when controlling for age, sex, low socio-economic status in addition to stressful life events in childhood and adolescence. Stressful childhood life events were associated with worse future orientation at baseline and negative life events experienced during adolescence were associated with both an increase in the trajectory of hopelessness as well as a decrease in the trajectory of future orientation. This study provides compelling evidence that the development of future orientation during adolescence is associated with a faster decline in hopelessness.

  17. OS104. Are preeclampsia and adverse obstetrical outcomes predictors for longterm cardiovascular disease?

    PubMed

    Sia, W W; Tsuyuki, R; Pertman, S; Hui, W

    2012-07-01

    Epidemiologic studies suggest that pregnancy complications such as preeclampsia, gestational diabetes, preterm delivery and low birth weight independently increase maternal risk for future development of cardiovascular disease. To further investigate whether preeclampsia, gestational diabetes, and adverse obstetrical outcomes such as placental abruption, intrauterine growth restriction and preterm delivery, are independent risk factors for longterm cardiovascular disease. This was a case-control study where 252 parous women (cases) with coronary artery disease were matched with a parous woman within 5 years of age with no known coronary artery disease (controls). Participants were recruited from the Royal Alexandra Hospital in cardiac catheterization lab recovery room in Edmonton, Canada. Women with significant angiographic coronary artery stenosis were eligible as cases and those without were eligible as controls. Participants were interviewed on their pregnancy histories and traditional cardiovascular risk factors, such as hypertension, diabetes etc. Descriptive statistics, chi-square tests and conditional regression analysis were performed. We recruited 244 cases and 246 controls. The average age was 66.3 and 65.8 respectively. Cases were more likely obese, had more pregnancies as well as traditional cardiovascular risk factors than controls. Adverse pregnancy outcomes were similar between the two groups except gestational hypertension. However, it was not statistically significant in the conditional logistic regression model. Independent risk factors for future cardiovascular diseases were: dyslipidemia (OR 12.8), hypertension (3.0), and being a current (OR 7.4) or former smoker (1.8). Adverse pregnancy outcomes In this study, adverse pregnancy outcomes were not independently associated with cardiovascular disorders. Our study was limited by recall bias, and ascertainment of diagnosis.Our study supports that dyslipidemia, hypertensiion and smoking increase future cardiovascular disease. Further studies are needed to examine a postpartum intervention model to proactively manage cardiovascular risk factors, such as lipids, in these at-risk women. Copyright © 2012. Published by Elsevier B.V.

  18. Aerodynamic Control-Augmentation Devices For Saturn-Class Launch Vehicles With Aft Centers Of Gravity

    NASA Technical Reports Server (NTRS)

    Barret, Chris

    1995-01-01

    Report describes study of aerodynamic flight-control-augmentation devices proposed for use in increasing payload capabilities of future launch vehicles by allowing more aft centers of gravity. Proposed all-movable devices not only provide increased control authority during ascent trajectory, but also reduce engine gimballing requirements and enhance crew safety. Report proposes various aerodynamic control surfaces mounted fore and aft on Saturn-class launch vehicle.

  19. Temporal Doppler Effect and Future Orientation: Adaptive Function and Moderating Conditions.

    PubMed

    Gan, Yiqun; Miao, Miao; Zheng, Lei; Liu, Haihua

    2017-06-01

    The objectives of this study were to examine whether the temporal Doppler effect exists in different time intervals and whether certain individual and environmental factors act as moderators of the effect. Using hierarchical linear modeling, we examined the existence of the temporal Doppler effect and the moderating effect of future orientation among 139 university students (Study 1), and then the moderating conditions of the temporal Doppler effect using two independent samples of 143 and 147 university students (Studies 2 and 3). Results indicated that the temporal Doppler effect existed in all of our studies, and that future orientation moderated the temporal Doppler effect. Further, time interval perception mediated the relationship between future orientation and the motivation to cope at long time intervals. Finally, positive affect was found to enhance the temporal Doppler effect, whereas control deprivation did not influence the effect. The temporal Doppler effect is moderated by the personality trait of future orientation and by the situational variable of experimentally manipulated positive affect. We have identified personality and environmental processes that could enhance the temporal Doppler effect, which could be valuable in cases where attention to a future task is necessary. © 2016 Wiley Periodicals, Inc.

  20. Impact of digital systems technology on man-vehicle systems research

    NASA Technical Reports Server (NTRS)

    Bretoi, R. N.

    1983-01-01

    The present study, based on a NASA technology assessment, examines the effect of new technologies on trends in crew-systems design and their implications from the vantage point of man-vehicle systems research. Those technologies that are most relevant to future trends in crew-systems design are considered along with problems associated with the introduction of rapidly changing technologies and systems concepts from a human-factors point of view. The technologies discussed include information processing, displays and controls, flight and propulsion control, flight and systems management, air traffic control, training and simulation, and flight and resource management. The historical evolution of cockpit systems design is used to illustrate past and possible future trends in man-vehicle systems research.

  1. Evaluation of laminar flow control system concepts for subsonic commercial transport aircraft

    NASA Technical Reports Server (NTRS)

    1978-01-01

    A two-year study conducted to establish a basis for industry decisions on the application of laminar flow control (LFC) to future commercial transports was presented. Areas of investigation included: (1) mission definition and baseline selection; (2) concepts evaluations; and (3) LFC transport configuration selection and component design. The development and evaluation of competing design concepts was conducted in the areas of aerodynamics, structures and materials, and systems. The results of supporting wind tunnel and laboratory testing on a full-scale LFC wing panel, suction surface opening concepts and structural samples were included. A final LFC transport was configured in incorporating the results of concept evaluation studies and potential performance improvements were assessed. Remaining problems together with recommendations for future research are discussed.

  2. A study of the Space Station Freedom response to the disturbance environment

    NASA Technical Reports Server (NTRS)

    Suleman, Afzal; Modi, V. J.; Venkayya, V. B.

    1994-01-01

    A relatively general formulation for studying the dynamics and control of an arbitrary spacecraft with interconnected flexible bodies has been developed. This self-contained and comprehensive numerical algorithm using system modes is applicable to a large class of spacecraft configurations of contemporary and future interest. Here, versatility of the approach is demonstrated through the dynamics and control studies aimed at the evolving Space Station Freedom.

  3. Benefit-cost analysis of spruce budworm (Choristoneura fumiferana Clem.) control: incorporating market and non-market values.

    PubMed

    Chang, Wei-Yew; Lantz, Van A; Hennigar, Chris R; MacLean, David A

    2012-01-01

    This study employs a benefit-cost analysis framework to estimate market and non-market benefits and costs of controlling future spruce budworm (Choristoneura fumiferana) outbreaks on Crown forest lands in New Brunswick, Canada. We used: (i) an advanced timber supply model to project potential timber volume saved, timber value benefits, and costs of pest control efforts; and (ii) a recent contingent valuation method analysis that evaluated non-market benefits (i.e., changes in recreation opportunities and existence values) of controlling future spruce budworm outbreaks in the Province. A total of six alternative scenarios were evaluated, including two uncontrolled future budworm outbreak severities (moderate vs. severe) and, for each severity, three control program levels (protecting 10%, 20%, or 40% of the susceptible Crown land forest area). The economic criteria used to evaluate each scenario included benefit-cost ratios and net present values. Under severe outbreak conditions, results indicated that the highest benefit-cost ratio (4.04) occurred when protecting 10% (284,000 ha) of the susceptible area, and the highest net present value ($111 M) occurred when protecting 20% (568,000 ha) of the susceptible area. Under moderate outbreak conditions, the highest benefit-cost ratio (3.24) and net present value ($58.7 M) occurred when protecting 10% (284,000 ha) of the susceptible area. Inclusion of non-market values generally increased the benefit-cost ratios and net present values of the control programs, and in some cases, led to higher levels of control being supported. Results of this study highlight the importance of including non-market values into the decision making process of forest pest management. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. Space vehicle electrical power processing distribution and control study. Volume 1: Summary

    NASA Technical Reports Server (NTRS)

    Krausz, A.

    1972-01-01

    A concept for the processing, distribution, and control of electric power for manned space vehicles and future aircraft is presented. Emphasis is placed on the requirements of the space station and space shuttle configurations. The systems involved are referred to as the processing distribution and control system (PDCS), electrical power system (EPS), and electric power generation system (EPGS).

  5. A systematic review of nosocomial waterborne infections in neonates and mothers.

    PubMed

    Moffa, Michelle; Guo, Wilson; Li, Trudy; Cronk, Ryan; Abebe, Lydia S; Bartram, Jamie

    2017-11-01

    Water is an important, overlooked, and controllable source of nosocomial infection. Hospitalized neonates and their mothers are particularly vulnerable to nosocomial waterborne infections. Our objectives through this systematic review were to: investigate water sources, reservoirs, and transmission routes that lead to nosocomial waterborne infections in neonates and their mothers; establish patient risk factors; compile measures for controlling outbreaks and recommended strategies for prevention; and identify information gaps to improve guidelines for reporting future outbreaks. We searched PubMed, Web of Science, Embase, and clinicaltrials.gov. Peer-reviewed studies reporting contaminated water as a route of transmission to neonates and/or their mothers were included. Twenty-five studies were included. The most common contaminated water sources in healthcare facilities associated with infection transmission were tap water, sinks, and faucets. Low birthweights, preterm or premature birth, and underlying disease increased neonatal risk of infection. Effective control measures commonly included replacing or cleaning faucets and increased or alternative methods for hand disinfection, and recommendations for prevention of future infections highlighted the need for additional surveillance. The implementation of control measures and recommended prevention strategies by healthcare workers and managing authorities of healthcare facilities and improved reporting of future outbreaks may contribute to a reduction in the incidence of nosocomial waterborne infections in neonates and their mothers. Copyright © 2017 Elsevier GmbH. All rights reserved.

  6. Trajectory control of robot manipulators with closed-kinematic chain mechanism

    NASA Technical Reports Server (NTRS)

    Nguyen, Charles C.; Pooran, Farhad J.; Premack, Timothy

    1987-01-01

    The problem of Cartesian trajectory control of a closed-kinematic chain mechanism robot manipulator, recently built at CAIR to study the assembly of NASA hardware for the future Space Station, is considered. The study is performed by both computer simulation and experimentation for tracking of three different paths: a straight line, a sinusoid, and a circle. Linearization and pole placement methods are employed to design controller gains. Results show that the controllers are robust and there are good agreements between simulation and experimentation. The results also show excellent tracking quality and small overshoots.

  7. Development of Future Scenario Emission Inventories for East Asia in Support of Multiple Modeling Studies

    NASA Astrophysics Data System (ADS)

    Kim, Y.; Woo, J. H.; Choi, K. C.; Lee, J. B.; Song, C. K.; Kim, S. K.; Hong, J.; Hong, S. C.; Zhang, Q.; Hong, C.; Tong, D.

    2015-12-01

    Future emission scenarios based on up-to-date regional socio-economic and control policy information were developed in support of climate-air quality integrated modeling research over East Asia. Two IPCC-participated Integrated Assessment Models(IAMs) were used to developed those scenario pathways. The two emission processing systems, KU-EPS and SMOKE-Asia, were used to convert these future scenario emissions to comprehensive chemical transport model-ready form. The NIER/KU-CREATE (Comprehensive Regional Emissions inventory for Atmospheric Transport Experiment) served as the regional base-year emission inventory. For anthropogenic emissions, it has 54 fuel classes, 201 sub-sectors and 13 pollutants, including CO2, CH4, N2O, SO2, NOx, CO, NMVOC, NH3, OC, BC, PM10, PM2.5, and mercury. Fast energy growth and aggressive penetration of the control measures make emissions projection very active for East Asia. Despite of more stringent air pollution control policies by the governments, however, air quality over the region seems not been improved as much - even worse in many cases. The needs of more scientific understanding of inter-relationship among emissions, transport, chemistry over the region are very high to effectively protect public health and ecosystems against ozone, fine particles, and other toxic pollutants in the air. After developing these long-term future emissions, therefore, we also tried to apply our future scenarios to develop the present emissions inventory for chemical weather forecasting and aircraft field campaign. On site, we will present; 1) the future scenario development framework and process methodologies, 2) initial development results of the future emission pathways, 3) present emission inventories from short-term projection, and 4) air quality modeling performance improvements over the region.

  8. Streptococcal upper respiratory tract infections and psychosocial stress predict future tic and obsessive-compulsive symptom severity in children and adolescents with Tourette syndrome and/or obsessive-compulsive disorder

    PubMed Central

    Lin, Haiqun; Williams, Kyle A.; Katsovich, Liliya; Findley, Diane B.; Grantz, Heidi; Lombroso, Paul J.; King, Robert A.; Bessen, Debra E.; Johnson, Dwight; Kaplan, Edward L.; Landeros-Weisenberger, Angeli; Zhang, Heping; Leckman, James F.

    2009-01-01

    Background: One goal of this prospective longitudinal study was to identify new group A beta hemolytic streptococcal (GABHS) infections in children and adolescents with Tourette syndrome (TS) and/or obsessive-compulsive disorder (OCD) compared to healthy control subjects. We then examined the power of GABHS infections and measures of psychosocial stress to predict future tic, obsessive-compulsive (OC), and depressive symptom severity. Methods: Consecutive ratings of tic, OC and depressive symptom severity were obtained for 45 cases and 41 matched control subjects over a two-year period. Clinical raters were blinded to the results of laboratory tests. Laboratory personnel were blinded to case or control status and clinical ratings. Structural equation modeling for unbalanced repeated measures was used to assess the sequence of new GABHS infections and psychosocial stress and their impact on future symptom severity. Results: Increases in tic and OC symptom severity did not occur after every new GABHS infection. However, the structural equation model found that these newly diagnosed infections were predictive of modest increases in future tic and OC symptom severity, but did not predict future depressive symptom severity. In addition, the inclusion of new infections in the model greatly enhanced, by a factor of three, the power of psychosocial stress in predicting future tic and OC symptom severity. Conclusions: Our data suggest that a minority of children with TS and early-onset OCD were sensitive to antecedent GABHS infections. These infections also enhanced the predictive power of current psychosocial stress on future tic and OC symptom severity. PMID:19833320

  9. An Analysis of the Dimensionality of the Pupil Control Ideology Scale.

    ERIC Educational Resources Information Center

    Graham, Steve; And Others

    1985-01-01

    The present study replicated an earlier investigation using the Pupil Control Ideology (PCI). The findings were congruent with earlier results. Consequently, it was recommended that the PCI should be refined and that the 10 item, unidimensional scale should be used in future investigations. (Author/LMO)

  10. Modelling climate change effects on Atlantic salmon: Implications for mitigation in regulated rivers.

    PubMed

    Sundt-Hansen, L E; Hedger, R D; Ugedal, O; Diserud, O H; Finstad, A G; Sauterleute, J F; Tøfte, L; Alfredsen, K; Forseth, T

    2018-08-01

    Climate change is expected to alter future temperature and discharge regimes of rivers. These regimes have a strong influence on the life history of most aquatic river species, and are key variables controlling the growth and survival of Atlantic salmon. This study explores how the future abundance of Atlantic salmon may be influenced by climate-induced changes in water temperature and discharge in a regulated river, and investigates how negative impacts in the future can be mitigated by applying different regulated discharge regimes during critical periods for salmon survival. A spatially explicit individual-based model was used to predict juvenile Atlantic salmon population abundance in a regulated river under a range of future water temperature and discharge scenarios (derived from climate data predicted by the Hadley Centre's Global Climate Model (GCM) HadAm3H and the Max Plank Institute's GCM ECHAM4), which were then compared with populations predicted under control scenarios representing past conditions. Parr abundance decreased in all future scenarios compared to the control scenarios due to reduced wetted areas (with the effect depending on climate scenario, GCM, and GCM spatial domain). To examine the potential for mitigation of climate change-induced reductions in wetted area, simulations were run with specific minimum discharge regimes. An increase in abundance of both parr and smolt occurred with an increase in the limit of minimum permitted discharge for three of the four GCM/GCM spatial domains examined. This study shows that, in regulated rivers with upstream storage capacity, negative effects of climate change on Atlantic salmon populations can potentially be mitigated by release of water from reservoirs during critical periods for juvenile salmon. Copyright © 2018. Published by Elsevier B.V.

  11. Endoscopic vs. Surgical Interventions for Painful Chronic Pancreatitis: What is Needed for Future Clinical Trials

    PubMed Central

    Windsor, John A; Reddy, Nageshwar D

    2017-01-01

    The treatment of painful chronic pancreatitis remains controversial. The available evidence from two randomized controlled trials favor surgical intervention, whereas an endotherapy-first approach is widely practiced. Chronic pancreatitis is complex disease with different genetic and environmental factors, different pain mechanisms and different treatment modalities including medical, endoscopic, and surgical. The widely practiced step-up approach remains unproven. In designing future clinical trials there are some important pre-requisites including a more comprehensive pain assessment tool, the optimization of conservative medical treatment and interventional techniques. Consideration should be given to the need of a control arm and the optimal timing of intervention. Pending better designed studies, the practical way forward is to identify subgroups of patients who clearly warrant endotherapy or surgery first, and to design the future clinical trials for the remainder. PMID:28079861

  12. Is ambiguity tolerance malleable? Experimental evidence with potential implications for future research

    PubMed Central

    Endres, Megan L.; Camp, Richaurd; Milner, Morgan

    2015-01-01

    We conducted two research studies to address the malleability of tolerance of ambiguity (TA) by manipulating situational ambiguity. Students participated in a semester-end assessment of their management skills (n = 306). In Study 1, students in low and moderate ambiguity conditions had significantly higher post-experiment TA, more positive change in self-efficacy, and marginally higher faculty ratings. In Study 2, a control group (n = 103) did not participate in the assessment and was established for comparison to the first study results. The Study 2 students reported TA significantly lower than Study 1 students in the low and moderate ambiguity conditions. The control group TA was not significantly different from that of the Study 1 high ambiguity condition. This further suggested TA’s situational malleability, as those who had controlled access to structured information appeared to have increased their TA over that observed in the other two groups. These results suggest that TA may be malleable. We review the relevant literature, offer hypotheses, report our analyses and findings, and then propose future research, and potential prescriptive applications in such areas as management development, assessment, and decision-making. PMID:26042059

  13. Team-Based Care with Pharmacists to Improve Blood Pressure: a Review of Recent Literature.

    PubMed

    Kennelty, Korey A; Polgreen, Linnea A; Carter, Barry L

    2018-01-18

    We review studies published since 2014 that examined team-based care strategies and involved pharmacists to improve blood pressure (BP). We then discuss opportunities and challenges to sustainment of team-based care models in primary care clinics. Multiple studies presented in this review have demonstrated that team-based care including pharmacists can improve BP management. Studies highlighted the cost-effectiveness of a team-based pharmacy intervention for BP control in primary care clinics. Little information was found on factors influencing sustainability of team-based care interventions to improve BP control. Future work is needed to determine the best populations to target with team-based BP programs and how to implement team-based approaches utilizing pharmacists in diverse clinical settings. Future studies need to not only identify unmet clinical needs but also address reimbursement issues and stakeholder engagement that may impact sustainment of team-based care interventions.

  14. Size does matter - span of control in hospitals.

    PubMed

    Holm-Petersen, Christina; Østergaard, Sussanne; Andersen, Per Bo Noergaard

    2017-04-10

    Purpose Centralization, mergers and cost reductions have generally led to increasing levels of span of control (SOC), and thus potentially to lower leadership capacity. The purpose of this paper is to explore how a large SOC impacts hospital staff and their leaders. Design/methodology/approach The study is based on a qualitative explorative case study of three large inpatient wards. Findings The study finds that the nursing staff and their frontline leaders experience challenges in regard to visibility and role of the leader, e.g., in creating overview, coordination, setting-up clear goals, following up and being in touch. However, large wards also provide flexibility and development possibilities. Practical implications The authors discuss the implications of these findings for decision makers in deciding future SOC and for future SOC research. Originality/value Only few studies have qualitatively explored the consequences of large SOC in hospitals.

  15. Evaluation of neurofeedback in ADHD: the long and winding road.

    PubMed

    Arns, Martijn; Heinrich, Hartmut; Strehl, Ute

    2014-01-01

    Among the clinical applications of neurofeedback, most research has been conducted in ADHD. As an introduction a short overview of the general history of neurofeedback will be given, while the main part of the paper deals with a review of the current state of neurofeedback in ADHD. A meta-analysis on neurofeedback from 2009 found large effect sizes for inattention and impulsivity and medium effects sizes for hyperactivity. Since 2009 several new studies, including 4 placebo-controlled studies, have been published. These latest studies are reviewed and discussed in more detail. The review focuses on studies employing (1) semi-active, (2) active, and (3) placebo-control groups. The assessment of specificity of neurofeedback treatment in ADHD is discussed and it is concluded that standard protocols such as theta/beta, SMR and slow cortical potentials neurofeedback are well investigated and have demonstrated specificity. The paper ends with an outlook on future questions and tasks. It is concluded that future controlled clinical trials should, in a next step, focus on such known protocols, and be designed along the lines of learning theory. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Methodological Characteristics and Future Directions for Plyometric Jump Training Research: A Scoping Review.

    PubMed

    Ramirez-Campillo, Rodrigo; Álvarez, Cristian; García-Hermoso, Antonio; Ramírez-Vélez, Robinson; Gentil, Paulo; Asadi, Abbas; Chaabene, Helmi; Moran, Jason; Meylan, Cesar; García-de-Alcaraz, Antonio; Sanchez-Sanchez, Javier; Nakamura, Fabio Y; Granacher, Urs; Kraemer, William; Izquierdo, Mikel

    2018-05-01

    Recently, there has been a proliferation of published articles on the effect of plyometric jump training, including several review articles and meta-analyses. However, these types of research articles are generally of narrow scope. Furthermore, methodological limitations among studies (e.g., a lack of active/passive control groups) prevent the generalization of results, and these factors need to be addressed by researchers. On that basis, the aims of this scoping review were to (1) characterize the main elements of plyometric jump training studies (e.g., training protocols) and (2) provide future directions for research. From 648 potentially relevant articles, 242 were eligible for inclusion in this review. The main issues identified related to an insufficient number of studies conducted in females, youths, and individual sports (~ 24.0, ~ 37.0, and ~ 12.0% of overall studies, respectively); insufficient reporting of effect size values and training prescription (~ 34.0 and ~ 55.0% of overall studies, respectively); and studies missing an active/passive control group and randomization (~ 40.0 and ~ 20.0% of overall studies, respectively). Furthermore, plyometric jump training was often combined with other training methods and added to participants' daily training routines (~ 47.0 and ~ 39.0% of overall studies, respectively), thus distorting conclusions on its independent effects. Additionally, most studies lasted no longer than 7 weeks. In future, researchers are advised to conduct plyometric training studies of high methodological quality (e.g., randomized controlled trials). More research is needed in females, youth, and individual sports. Finally, the identification of specific dose-response relationships following plyometric training is needed to specifically tailor intervention programs, particularly in the long term.

  17. Arms control and The President's Strategic Defense Initiative

    NASA Astrophysics Data System (ADS)

    Bon, J. J.

    1985-04-01

    The President's Strategic Defense Initiative (SDI) provides the hope for eliminating the threat from ballistic missiles. This study evaluates the impact of SDI on existing and future arms control agreements. Because new or modified space-related treaties are a probable result of the SDI, this study concludes that the best single strategy for arms control negotiations is to preserve overall US interests and maintain open technological options vice severely limiting any space technology that might some day become part of a space-based defensive system.

  18. 17 CFR 18.00 - Information to be furnished by traders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Purchases and sales of futures for commodities or for derivatives positions; and (e) Options exercised... controls, or has held, owned or controlled, a reportable futures or options position in a commodity shall... reports to the Commission concerning transactions and positions in such futures or options. Reports shall...

  19. The neural basis of temporal order processing in past and future thought.

    PubMed

    D'Argembeau, Arnaud; Jeunehomme, Olivier; Majerus, Steve; Bastin, Christine; Salmon, Eric

    2015-01-01

    Although growing evidence has shown that remembering the past and imagining the future recruit a common core network of frontal-parietal-temporal regions, the extent to which these regions contribute to the temporal dimension of autobiographical thought remains unclear. In this fMRI study, we focused on the event-sequencing aspect of time and examined whether ordering past and future events involve common neural substrates. Participants had to determine which of two past (or future) events occurred (or would occur) before the other, and these order judgments were compared with a task requiring to think about the content of the same past or future events. For both past and future events, we found that the left posterior hippocampus was more activated when establishing the order of events, whereas the anterior hippocampus was more activated when representing their content. Aside from the hippocampus, most of the brain regions that were activated when thinking about temporal order (notably the intraparietal sulcus, dorsolateral pFC, dorsal anterior cingulate, and visual cortex) lied outside the core network and may reflect the involvement of controlled processes and visuospatial imagery to locate events in time. Collectively, these findings suggest (a) that the same processing operations are engaged for ordering past events and planned future events in time, (b) that anterior and posterior portions of the hippocampus are involved in processing different aspects of autobiographical thought, and (c) that temporal order is not necessarily an intrinsic property of memory or future thought but instead requires additional, controlled processes.

  20. Women's perceived internal control of future pregnancy outcomes and its related factors.

    PubMed

    Maleki, Azam; Mazloomzadeh, Saeideh

    2013-03-01

    With regards to the importance of women's beliefs in improving pregnancy outcomes, this study was performed to determine the perceived internal control on future pregnancy outcomes and its related factors in women who participated in pre-marital counseling. In a cross-sectional study, women's perceived internal control was investigated. The study population comprised the women in reproductive age of whom 400 were selected by random sampling. Data collection instrument was a questionnaire consisting of demographic, pre-conceptional care, and internal control questions. Two categories of favorite and not favorite levels of internal control were defined based on the total score. The validity of the questionnaire was determined via content validity method by use of experts' opinion and its reliability was evaluated through the calculation of Cronbach's alpha coefficient which was 0.76. Data were analyzed through frequency tables, correlation coefficient, and Chi-square test at the confidence level of 0.95. Two hundred sixty-five (65%) women had a good perceived internal control and it was significantly associated with the age, educational level, and hearing about pre-conceptional care. The internal control score also showed a positive and significant correlation with both age and the subject knowledge about folic acid (r = 0.19 and r = 0.15, respectively). The majority of women had a favorite perceived internal control. Since age and educational level were the affecting factors on the perceived internal control of women, promoting the level of internal control in young women and those with low education in pre-marital counseling classes seems necessary.

  1. Epidemiology of East Coast fever (Theileria parva infection) in Kenya: past, present and the future.

    PubMed

    Gachohi, John; Skilton, Rob; Hansen, Frank; Ngumi, Priscilla; Kitala, Philip

    2012-09-07

    In this article, we review the epidemiology of East Coast fever (ECF), a tick-borne infection of cattle, in Kenya. The major factors associated with epidemiology of ECF include the agro-ecological zone (AEZ), livestock production system (LPS) and both animal breed and age. These factors appear to influence the epidemiology of ECF through structured gradients. We further show that the gradients are dynamically shaped by socio-demographic and environmental processes. For a vector-borne disease whose transmission depends on environmental characteristics that influence vector dynamics, a change in the environment implies a change in the epidemiology of the disease. The review recommends that future ECF epidemiological studies should account for these factors and the dynamic interactions between them. In Kenya, ECF control has previously relied predominantly on tick control using acaricides and chemotherapy while ECF immunization is steadily being disseminated. We highlight the contribution of ECF epidemiology and economics in the design of production system and/or geographical area-specific integrated control strategies based on both the dynamic epidemiological risk of the disease and economic impacts of control strategies. In all production systems (except marginal areas), economic analyses demonstrate that integrated control in which ECF immunization is always an important component, can play an important role in the overall control of the disease. Indeed, Kenya has recently approved ECF immunization in all production systems (except in marginal areas). If the infrastructure of the vaccine production and distribution can be heightened, large ECF endemic areas are expected to be endemically stable and the disease controlled. Finally, the review points the way for future research by identifying scenario analyses as a critical methodology on which to base future investigations on how both dynamic livestock management systems and patterns of land use influence the dynamics and complexity of ECF epidemiology and the implications for control.

  2. Epidemiology of East Coast fever (Theileria parva infection) in Kenya: past, present and the future

    PubMed Central

    2012-01-01

    In this article, we review the epidemiology of East Coast fever (ECF), a tick-borne infection of cattle, in Kenya. The major factors associated with epidemiology of ECF include the agro-ecological zone (AEZ), livestock production system (LPS) and both animal breed and age. These factors appear to influence the epidemiology of ECF through structured gradients. We further show that the gradients are dynamically shaped by socio-demographic and environmental processes. For a vector-borne disease whose transmission depends on environmental characteristics that influence vector dynamics, a change in the environment implies a change in the epidemiology of the disease. The review recommends that future ECF epidemiological studies should account for these factors and the dynamic interactions between them. In Kenya, ECF control has previously relied predominantly on tick control using acaricides and chemotherapy while ECF immunization is steadily being disseminated. We highlight the contribution of ECF epidemiology and economics in the design of production system and/or geographical area-specific integrated control strategies based on both the dynamic epidemiological risk of the disease and economic impacts of control strategies. In all production systems (except marginal areas), economic analyses demonstrate that integrated control in which ECF immunization is always an important component, can play an important role in the overall control of the disease. Indeed, Kenya has recently approved ECF immunization in all production systems (except in marginal areas). If the infrastructure of the vaccine production and distribution can be heightened, large ECF endemic areas are expected to be endemically stable and the disease controlled. Finally, the review points the way for future research by identifying scenario analyses as a critical methodology on which to base future investigations on how both dynamic livestock management systems and patterns of land use influence the dynamics and complexity of ECF epidemiology and the implications for control. PMID:22958352

  3. Modified Dynamic Inversion to Control Large Flexible Aircraft: What's Going On?

    NASA Technical Reports Server (NTRS)

    Gregory, Irene M.

    1999-01-01

    High performance aircraft of the future will be designed lighter, more maneuverable, and operate over an ever expanding flight envelope. One of the largest differences from the flight control perspective between current and future advanced aircraft is elasticity. Over the last decade, dynamic inversion methodology has gained considerable popularity in application to highly maneuverable fighter aircraft, which were treated as rigid vehicles. This paper explores dynamic inversion application to an advanced highly flexible aircraft. An initial application has been made to a large flexible supersonic aircraft. In the course of controller design for this advanced vehicle, modifications were made to the standard dynamic inversion methodology. The results of this application were deemed rather promising. An analytical study has been undertaken to better understand the nature of the made modifications and to determine its general applicability. This paper presents the results of this initial analytical look at the modifications to dynamic inversion to control large flexible aircraft.

  4. The value of a registry negative urine pregnancy test for the prediction of a future unintended pregnancy among young women.

    PubMed

    Rottenstreich, Misgav; Grisaru-Granovsky, Sorina; Rottenstreich, Amihai

    2018-06-01

    Performance of urine pregnancy test in general adolescents' clinic reflects caregiver or woman's concern that there might be a pregnancy. We aimed to assess whether young-unmarried women in whom a negative urine pregnancy test was registered would be at increased risk of a future unintended pregnancy. The study cohort included consecutive women drafted by the Israeli military between 2013 and 2015. The risk of unintended pregnancy was compared between women with a negative urine pregnancy test (n = 2774), the study group, and those in whom urine pregnancy test was not carried out (n = 126,659), the control group. During the study period, 2147 (1.7%) women experienced an unintended pregnancy. The risk of unintended pregnancy was significantly higher in patients in whom a past pregnancy test was negative 4.3% (n = 118), as compared with the control group 1.6% (n = 2028) (odds ratio [OR], 2.7; 95% confidence interval [CI], 2.23-3.26). In multivariate analysis history of a negative pregnancy test results was an independent predictor for a future unintended pregnancy (adjusted OR, 2.0; 95% CI, 1.63-2.52). A history of a negative pregnancy test among young conscripted women is a significant risk indicator for a future unintended pregnancy. Directed efforts should be made in this particular vulnerable group of patients.

  5. Delegation control of multiple unmanned systems

    NASA Astrophysics Data System (ADS)

    Flaherty, Susan R.; Shively, Robert J.

    2010-04-01

    Maturing technologies and complex payloads coupled with a future objective to reduce the logistics burden of current unmanned aerial systems (UAS) operations require a change to the 2-crew employment paradigm. Increased automation and operator supervisory control of unmanned systems have been advocated to meet the objective of reducing the crew requirements, while managing future technologies. Specifically, a delegation control employment strategy has resulted in reduced workload and higher situation awareness for single operators controlling multiple unmanned systems in empirical studies1,2. Delegation control is characterized by the ability for an operator to call a single "play" that initiates prescribed default actions for each vehicle and associated sensor related to a common mission goal. Based upon the effectiveness of delegation control in simulation, the U.S. Army Aeroflightdynamics Directorate (AFDD) developed a Delegation Control (DelCon) operator interface with voice recognition implementation for play selection, real-time play modification, and play status with automation transparency to enable single operator control of multiple unmanned systems in flight. AFDD successfully demonstrated delegation control in a Troops-in-Contact mission scenario at Ft. Ord in 2009. This summary showcases the effort as a beneficial advance in single operator control of multiple UAS.

  6. An fMRI investigation of the relationship between future imagination and cognitive flexibility

    PubMed Central

    Roberts, R.P.; Wiebels, K.; Sumner, R.L.; van Mulukom, V.; Grady, C.L.; Schacter, D.L.; Addis, D.R.

    2016-01-01

    While future imagination is largely considered to be a cognitive process grounded in default mode network activity, studies have shown that future imagination recruits regions in both default mode and frontoparietal control networks. In addition, it has recently been shown that the ability to imagine the future is associated with cognitive flexibility, and that tasks requiring cognitive flexibility result in increased coupling of the default mode network with frontoparietal control and salience networks. In the current study, we investigated the neural correlates underlying the association between cognitive flexibility and future imagination in two ways. First, we experimentally varied the degree of cognitive flexibility required during future imagination by manipulating the disparateness of episodic details contributing to imagined events. To this end, participants generated episodic details (persons, locations, objects) within three social spheres; during fMRI scanning they were presented with sets of three episodic details all taken from the same social sphere (Congruent condition) or different social spheres (Incongruent condition) and required to imagine a future event involving the three details. We predicted that, relative to the Congruent condition, future simulation in the Incongruent condition would be associated with increased activity in regions of the default mode, frontoparietal and salience networks. Second, we hypothesized that individual differences in cognitive flexibility, as measured by performance on the Alternate Uses Task, would correspond to individual differences in the brain regions recruited during future imagination. A task partial least squares (PLS) analysis showed that the Incongruent condition resulted in an increase in activity in regions in salience networks (e.g. the insula) but, contrary to our prediction, reduced activity in many regions of the default mode network (including the hippocampus). A subsequent functional connectivity (within-subject seed PLS) analysis showed that the insula exhibited increased coupling with default mode regions during the Incongruent condition. Finally, a behavioral PLS analysis showed that individual differences in cognitive flexibility were associated with differences in activity in a number of regions from frontoparietal, salience and default-mode networks during both future imagination conditions, further highlighting that the cognitive flexibility underlying future imagination is grounded in the complex interaction of regions in these networks. PMID:27908591

  7. Predicting Health Resilience in Pediatric Type 1 Diabetes: A Test of the Resilience Model Framework.

    PubMed

    Rohan, Jennifer M; Huang, Bin; Pendley, Jennifer Shroff; Delamater, Alan; Dolan, Lawrence; Reeves, Grafton; Drotar, Dennis

    2015-10-01

    This research examined whether individual and family-level factors during the transition from late childhood to early adolescence protected individuals from an increased risk of poor glycemic control across time, which is a predictor of future diabetes-related complications (i.e., health resilience). This longitudinal, multisite study included 239 patients with type 1 diabetes and their caregivers. Glycemic control was based on hemoglobin A1c. Individual and family-level factors included: demographic variables, youth behavioral regulation, adherence (frequency of blood glucose monitoring), diabetes self-management, level of parental support for diabetes autonomy, level of youth mastery and responsibility for diabetes management, and diabetes-related family conflict. Longitudinal mixed-effects logistic regression indicated that testing blood glucose more frequently, better self-management, and less diabetes-related family conflict were indicators of health resilience. Multiple individual and family-level factors predicted risk for future health complications. Future research should develop interventions targeting specific individual and family-level factors to sustain glycemic control within recommended targets, which reduces the risk of developing future health complications during the transition to adolescence and adulthood. © The Author 2015. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  8. Pointing and control system enabling technology for future automated space missions

    NASA Technical Reports Server (NTRS)

    Dahlgren, J. B.

    1978-01-01

    Future automated space missions present challenging opportunities in the pointing-and-control technology disciplines. The enabling pointing-and-control system technologies for missions from 1985 to the year 2000 were identified and assessed. A generic mission set including Earth orbiter, planetary, and other missions which predominantly drive the pointing-and-control requirements was selected for detailed evaluation. Technology candidates identified were prioritized as planning options for future NASA-OAST advanced development programs. The primary technology thrusts in each candidate program were cited, and advanced development programs in pointing-and-control were recommended for the FY 80 to FY 87 period, based on these technology thrusts.

  9. Recall of vegetable eating affects future predicted enjoyment and choice of vegetables in British University undergraduate students.

    PubMed

    Robinson, Eric; Blissett, Jackie; Higgs, Suzanne

    2011-10-01

    Predictions about enjoyment of future experiences are influenced by recalling similar past experiences. However, little is known about the relationship between hedonic memories of past eating episodes and future eating behavior. We investigated recall of previous experiences of eating vegetables and the effect of recall on future predicted liking for and consumption of vegetables. British University undergraduate students were asked to retrieve memories of previous occasions when they ate vegetables and were asked to rate how enjoyable those experiences were (Study 1, n=54). The effect of different types of memory recall (including vegetable eating recall) and visualization of someone else eating vegetables (to control for priming effects) on predicted likelihood of choosing vegetables and predicted enjoyment of eating vegetables was examined (Study 2, n=95). Finally, the effect of recalling vegetable eating memories on actual food choice from a buffet was assessed (Study 3, n=63). It is reported that people recall positive memories of past vegetable consumption (P<0.05) and that reminding people of these experiences results in higher predicted future liking for vegetables (P<0.05) and choice of a larger portion size of vegetables (P<0.05) compared with recall of a personal nonfood memory, a nonvegetable food memory, or visualization of someone else enjoying eating vegetables (increase of approximately 70% in vegetable portion size compared to controls). The results suggest that recall of previous eating experiences could be a potential strategy for altering food choices. Copyright © 2011 American Dietetic Association. Published by Elsevier Inc. All rights reserved.

  10. Continuous subcutaneous insulin infusion therapy and multiple daily insulin injections in type 1 diabetes mellitus: a comparative overview and future horizons.

    PubMed

    Thabit, Hood; Hovorka, Roman

    2016-01-01

    Continuous subcutaneous insulin infusion (CSII) therapy is currently accepted as a treatment strategy for type 1 diabetes. Transition from multiple daily injection therapy (MDI; including basal-bolus regimens) to CSII is based on expectations of better metabolic control and fewer hypoglycaemic events. Evidence to date has not been always conclusive. Evidence for CSII and MDI in terms of glycaemic control, hypoglycaemia and psychosocial outcomes is reviewed in the adult and paediatric population with type 1 diabetes. Findings from studies on threshold-based insulin pump suspension and predictive low glucose management (PLGM) are outlined. Limitations of current CSII application and future technological developments are discussed. Glycaemic control and quality of life (QOL) may be improved by CSII compared to MDI depending on baseline HbA1c and hypoglycaemia rates. Future studies are expected to provide evidence on clinical and cost effectiveness in those who will benefit the most. Training, structured education and support are important to benefit from CSII. Novel technological approaches linking continuous glucose monitoring (CGM) and CSII may help mitigate against frequent hypoglycaemia in those at risk. Development of glucose-responsive automated closed-loop insulin delivery systems may reduce the burden of disease management and improve outcomes in type 1 diabetes.

  11. Comparison of performance on the Shipley Institute of Living Scale, air traffic control specialist selection test, and FAA Academy screen.

    DOT National Transportation Integrated Search

    1992-11-01

    This study was conducted to establish norms for ATCS personnel on a group test of intellectual functioning, the Shipley Institute of Living Scale (SILS), to screen subjects for future research on the effects of Air Traffic Control Specialist (ATCS) r...

  12. Inventory and Expressive Measures of Locus of Control and Academic Performance: A 5-Year Outcome Study

    ERIC Educational Resources Information Center

    Otten, Mark W.

    1977-01-01

    Rotter's Internal External Locus of Control Scale and Ezekiel's Personal Future Autobiography were administered to 45 freshmen and 45 graduate students. Although the two tests had negative nonsignificant correlations, both tests were positively correlated with academic achievement (specifically, graduation within five years) for the internal locus…

  13. Anti-Pollution Behavior: A Function of Perceived Outcome and Locus of Control

    ERIC Educational Resources Information Center

    Trigg, Linda J.; And Others

    1976-01-01

    This study investigated the moderating effects of perceived outcome on the relationship between activism (social action) in the form of anti-pollution behavior and locus of control (I-E). Among subjects optimistic about future levels of pollution, internally-oriented individuals engaged in more anti-pollution activities and had more accurate…

  14. Factors associated with the intention of health care personnel to respond to a disaster.

    PubMed

    Connor, Susan B

    2014-12-01

    Over the past decade, numerous groups of researchers have studied the willingness of health care personnel (HCP) to respond when a disaster threatens the health of a community. Not one of those studies reported that 100% of HCP were willing to work during a public-health event (PHE). The objective of this study was to explore factors associated with the intent of HCP to respond to a future PHE. The theory of planned behavior (TPB) framed this cross-sectional study. Data were obtained via a web-based survey from 305 HCP. Linear associations between the TPB-based predictor and outcome variables were examined using Pearson's correlations. Differences between two groups of HCP were calculated using independent t tests. A model-generating approach was used to develop and assess a series of TBP-based observed variable structural equation models for prediction of intent to respond to a future PHE and to explore moderating and mediating effects. The beginning patterns of relationships identified by the correlation matrix and t tests were evident in the final structural equation model, even though the patterns of prediction differed from those posited by the theory. Outcome beliefs had both a significant, direct effect on intention and an indirect effect on intention that was mediated by perceived behavioral control. Control beliefs appeared to influence intention through perceived behavioral control, as posited by the TPB, and unexpectedly through subjective norm. Subjective norm not only mediated the relationship between control beliefs and intention, but also the relationship between referent beliefs and intention. Additionally, professional affiliation seemed to have a moderating effect on intention. The intention to respond was influenced primarily by normative and control factors. The intent of nurses to respond to a future PHE was influenced most by the control factors, whereas the intent of other HCP was shaped more by the normative factors. Health care educators can bolster the normative and control factors through education by focusing on team building and knowledge related to accessing supplies and support needed to respond when a disaster occurs.

  15. Implicit but not explicit self-esteem predicts future depressive symptomatology.

    PubMed

    Franck, Erik; De Raedt, Rudi; De Houwer, Jan

    2007-10-01

    To date, research on the predictive validity of implicit self-esteem for depressive relapse is very sparse. In the present study, we assessed implicit self-esteem using the Name Letter Preference Task and explicit self-esteem using the Rosenberg self-esteem scale in a group of currently depressed patients, formerly depressed individuals, and never depressed controls. In addition, we examined the predictive validity of explicit, implicit, and the interaction of explicit and implicit self-esteem in predicting future symptoms of depression in formerly depressed individuals and never depressed controls. The results showed that currently depressed individuals reported a lower explicit self-esteem as compared to formerly depressed individuals and never depressed controls. In line with previous research, all groups showed a positive implicit self-esteem not different from each other. Furthermore, after controlling for initial depressive symptomatology, implicit but not explicit self-esteem significantly predicted depressive symptoms at six months follow-up. Although implicit self-esteem assessed with the Name Letter Preference Test was not different between formerly depressed individuals and never depressed controls, the findings suggest it is an interesting variable in the study of vulnerability for depression relapse.

  16. Future planning in preschool children.

    PubMed

    Moffett, Lillie; Moll, Henrike; FitzGibbon, Lily

    2018-05-01

    The capacity to plan ahead and provide the means for future ends is an important part of human practical reasoning. When this capacity develops in ontogeny is the matter of an ongoing debate. In this study, 4- and 5-year-olds performed a future planning task in which they had to create the means (a picture of a particular object, e.g., a banana) that was necessary to address a future end (of completing a game in which such a picture was missing). Children of both ages drew more targets than children in a control condition in which there was no future end to be pursued. Along with prior findings, the results suggest a major progression in children's future thinking between 3 and 5 years. Our findings expand on prior knowledge by showing that young children cannot only identify the probate means to future ends but determine such ends and create the means to achieve them, thus offering compelling evidence for future planning. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  17. Motivation to serve in the military influences vulnerability to future posttraumatic stress disorder.

    PubMed

    Kaplan, Zeev; Weiser, Mark; Reichenberg, Abraham; Rabinowitz, Jonathan; Caspi, Asaf; Bodner, Ehud; Zohar, Joseph

    2002-01-31

    High motivation and belief in a cause have been reported to be protective against posttraumatic stress disorder (PTSD), while below-average intellectual functioning and poor educational achievements have been reported to increase vulnerability to PTSD. The main goal of this study was to assess the effect of education, and intellectual and behavioral functioning on the risk for future PTSD. Data collected before exposure to trauma, on intellectual and behavioral functioning, and educational achievements of 901 male Israeli adolescents who had performed pre-induction screening tests by the Israeli Draft Board, and were later diagnosed with PTSD, were compared with a control group of adolescents who were not later diagnosed with PTSD. Future PTSD patients had significantly lower intelligence, fewer years of formal education and lower scores on a scale assessing motivation to serve in the military, in comparison with the control group, with effect sizes (ES) ranging from 0.14-0.34. In contrast, future PTSD patients scored significantly higher on a scale assessing social functioning, ES=0.13. However, when controlling for the differences in motivation to serve, all of these differences disappeared. In this cohort, although slightly below average intellectual functioning and formal education, and better social functioning, independently increased vulnerability to suffer from PTSD, these associations disappeared when the future PTSD patients' lower motivation to serve in the military was included in the analysis. This suggests that low motivation to serve in the military might increase vulnerability for PTSD.

  18. Future applications of artificial intelligence to Mission Control Centers

    NASA Technical Reports Server (NTRS)

    Friedland, Peter

    1991-01-01

    Future applications of artificial intelligence to Mission Control Centers are presented in the form of the viewgraphs. The following subject areas are covered: basic objectives of the NASA-wide AI program; inhouse research program; constraint-based scheduling; learning and performance improvement for scheduling; GEMPLAN multi-agent planner; planning, scheduling, and control; Bayesian learning; efficient learning algorithms; ICARUS (an integrated architecture for learning); design knowledge acquisition and retention; computer-integrated documentation; and some speculation on future applications.

  19. Examining temporal alterations in Social Anxiety Disorder and Posttraumatic Stress Disorder: The relation between autobiographical memory, future goals, and current self-views.

    PubMed

    Krans, Julie; Peeters, Manon; Näring, Gérard; Brown, Adam D; de Bree, June; van Minnen, Agnes

    2017-12-01

    The self is a multi-faceted and temporally dynamic construct reflecting representations and beliefs about identity in the past, present, and future. Clinical studies have shown that individuals with Posttraumatic Stress Disorder (PTSD) and Social Anxiety Disorder (SAD) exhibit alterations in self-related processing but these studies have focused primarily on memory. Few studies in PTSD and SAD have examined self-related processing for the present and future, and no studies have directly compared these processes across these two disorders. Individuals diagnosed with PTSD (n=21), SAD (n=21), and healthy controls (n=21) completed cognitive tasks related to the past, present, and future. Disorder congruent temporal alterations were found across both disorders. Further, regression analyses revealed that trauma-related memories were significantly predicted by future goals related to the trauma, whereas social anxiety-related recall was predicted by current socially anxious self-views. Thus, although self-related processing may be common in PTSD and SAD, those aspects of the self most strongly associated with disorder-congruent recall differ by disorder. Self-alterations may be modifiable and developing a better understanding of past, present, and future self-processing might aid in the development of interventions that target these process. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Development of self-control in children aged 3 to 9 years: Perspective from a dual-systems model

    PubMed Central

    Tao, Ting; Wang, Ligang; Fan, Chunlei; Gao, Wenbin

    2014-01-01

    The current study tested a set of interrelated theoretical propositions based on a dual-systems model of self-control. Data were collected from 2135 children aged 3 to 9 years. The results suggest that (a) there was positive growth in good self-control, whereas poor control remained relatively stable; and (b) girls performed better than boys on tests of good self-control. The results are discussed in terms of their implications for a dual-systems model of self-control theory and future empirical work. PMID:25501669

  1. Fundamental constructs in food parenting practices: a content map to guide future research

    PubMed Central

    Ward, Dianne S.; Fisher, Jennifer O.; Faith, Myles S.; Hughes, Sheryl O.; Kremers, Stef P.J.; Musher-Eizenman, Dara R.; O’Connor, Teresia M.; Patrick, Heather; Power, Thomas G.

    2016-01-01

    Although research shows that “food parenting practices” can impact children’s diet and eating habits, current understanding of the impact of specific practices has been limited by inconsistencies in terminology and definitions. This article represents a critical appraisal of food parenting practices, including clear terminology and definitions, by a working group of content experts. The result of this effort was the development of a content map for future research that presents 3 overarching, higher-order food parenting constructs – coercive control, structure, and autonomy support – as well as specific practice subconstructs. Coercive control includes restriction, pressure to eat, threats and bribes, and using food to control negative emotions. Structure includes rules and limits, limited/guided choices, monitoring, meal- and snacktime routines, modeling, food availability and accessibility, food preparation, and unstructured practices. Autonomy support includes nutrition education, child involvement, encouragement, praise, reasoning, and negotiation. Literature on each construct is reviewed, and directions for future research are offered. Clear terminology and definitions should facilitate cross-study comparisons and minimize conflicting findings resulting from previous discrepancies in construct operationalization. PMID:26724487

  2. Induced optimism as mental rehearsal to decrease depressive predictive certainty.

    PubMed

    Miranda, Regina; Weierich, Mariann; Khait, Valerie; Jurska, Justyna; Andersen, Susan M

    2017-03-01

    The present study examined whether practice in making optimistic future-event predictions would result in change in the hopelessness-related cognitions that characterize depression. Individuals (N = 170) with low, mild, and moderate-to-severe depressive symptoms were randomly assigned to a condition in which they practiced making optimistic future-event predictions or to a control condition in which they viewed the same stimuli but practiced determining whether a given phrase contained an adjective. Overall, individuals in the induced optimism condition showed increases in optimistic predictions, relative to the control condition, as a result of practice, but only individuals with moderate-to-severe symptoms of depression who practiced making optimistic future-event predictions showed decreases in depressive predictive certainty, relative to the control condition. In addition, they showed gains in efficiency in making optimistic predictions over the practice blocks, as assessed by response time. There was no difference in depressed mood by practice condition. Mental rehearsal might be one way of changing the hopelessness-related cognitions that characterize depression. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Electroencephalography (EEG) Based Control in Assistive Mobile Robots: A Review

    NASA Astrophysics Data System (ADS)

    Krishnan, N. Murali; Mariappan, Muralindran; Muthukaruppan, Karthigayan; Hijazi, Mohd Hanafi Ahmad; Kitt, Wong Wei

    2016-03-01

    Recently, EEG based control in assistive robot usage has been gradually increasing in the area of biomedical field for giving quality and stress free life for disabled and elderly people. This study reviews the deployment of EGG based control in assistive robots, especially for those who in need and neurologically disabled. The main objective of this paper is to describe the methods used for (i) EEG data acquisition and signal preprocessing, (ii) feature extraction and (iii) signal classification methods. Besides that, this study presents the specific research challenges in the designing of these control systems and future research directions.

  4. Future shift of the relative roles of precipitation and temperature in controlling annual runoff in the conterminous United States

    Treesearch

    Kai Duan; Ge Sun; Steven G. McNulty; Peter V. Caldwell; Erika C. Cohen; Shanlei Sun; Heather D. Aldridge; Decheng Zhou; Liangxia Zhang; Yang Zhang

    2017-01-01

    This study examines the relative roles of cli- matic variables in altering annual runoff in the contermi- nous United States (CONUS) in the 21st century, using a monthly ecohydrological model (the Water Supply Stress In- dex model, WaSSI) driven with historical records and future scenarios constructed from 20 Coupled Model Intercompar- ison Project Phase 5 (CMIP5)...

  5. Cancer Control: A Look to the Future

    Cancer.gov

    Judith Mackay, MB ChB, FRCP (Edin), FRCP (Lon), an international expert from Hong Kong in tobacco control, with posts as a senior advisor for the World Lung Foundation and the Bloomberg Initiative to Reduce Tobacco Use, presented "Cancer Control: A Look to the Future".

  6. Will studies in individuals with systemic lupus erythematosus be the key to future HIV vaccine design?

    PubMed

    Bonsignori, Mattia

    2014-11-01

    The induction of HIV-1 broadly neutralizing antibodies (bnAbs) remains the primary goal of a preventive HIV-1 vaccine but no HIV-1 vaccine candidate has succeeded in inducing bnAbs. All the bnAbs isolated from chronically HIV-1 infected subjects display one or more traits associated with control by host tolerance and immunoregulatory mechanisms, including reactivity against self antigens. Recent studies on a HIV-1 patient with concurrent systemic lupus erythematosus have informed on how similar bnAbs are to typical autoantibodies controlled by immune tolerance mechanisms. Future studies aimed at elucidating the intersection between autoantibodies generated in the context of systemic lupus erythematosus and the development of HIV-1 bnAbs will further our knowledge of specific roadblocks that hamper the production of bnAbs and, ultimately, inform us on how to implement vaccine strategies to circumvent them.

  7. Investigating Factors that Generate and Maintain Variation in Migratory Orientation: A Primer for Recent and Future Work.

    PubMed

    Delmore, Kira E; Liedvogel, Miriam

    2016-01-01

    The amazing accuracy of migratory orientation performance across the animal kingdom is facilitated by the use of magnetic and celestial compass systems that provide individuals with both directional and positional information. Quantitative genetics analyses in several animal systems suggests that migratory orientation has a strong genetic component. Nevertheless, the exact identity of genes controlling orientation remains largely unknown, making it difficult to obtain an accurate understanding of this fascinating behavior on the molecular level. Here, we provide an overview of molecular genetic techniques employed thus far, highlight the pros and cons of various approaches, generalize results from species-specific studies whenever possible, and evaluate how far the field has come since early quantitative genetics studies. We emphasize the importance of examining different levels of molecular control, and outline how future studies can take advantage of high-resolution tracking and sequencing techniques to characterize the genomic architecture of migratory orientation.

  8. Domains of unprofessional behavior during medical school associated with future disciplinary action by a state medical board.

    PubMed

    Teherani, Arianne; Hodgson, Carol S; Banach, Mary; Papadakis, Maxine A

    2005-10-01

    In a previous study, we showed that unprofessional behavior in medical school was associated with subsequent disciplinary action. This study expands on that work by identifying the domains of unprofessional behavior that are most problematic. In this retrospective case-control study, negative comments were extracted from student files for 68 case (disciplined) and 196 matched control (nondisciplined) physicians. Comments were analyzed qualitatively and subsequently quantified. The relationship between domains of behavior and disciplinary action was established through chi-square tests and multivariate analysis of variance. Three domains of unprofessional behavior emerged that were related significantly to later disciplinary outcome: (1) poor reliability and responsibility, (2) lack of self-improvement and adaptability, and (3) poor initiative and motivation. Three critical domains of professionalism associated with future disciplinary action have been defined. These findings could lead to focused remediation strategies and policy decisions.

  9. Status and trends in active control technology

    NASA Technical Reports Server (NTRS)

    Rediess, H. A.; Szalai, K. J.

    1975-01-01

    The emergence of highly reliable fly-by-wire flight control systems makes it possible to consider a strong reliance on automatic control systems in the design optimization of future aircraft. This design philosophy has been referred to as the control configured vehicle approach or the application of active control technology. Several studies and flight tests sponsored by the Air Force and NASA have demonstrated the potential benefits of control configured vehicles and active control technology. The present status and trends of active control technology are reviewed and the impact it will have on aircraft designs, design techniques, and the designer is predicted.

  10. Passive Thermal Control Challenges for Future Exploration Missions

    NASA Technical Reports Server (NTRS)

    Rickman, Steven L.

    2004-01-01

    This slide presentation reviews the importance of developing passive thermal control for the future exploration missions envisioned in President Bush's call for human exploration of the Moon and Mars. Included in the presentation is a review of the conditions that make the thermal control very challenging on the Moon and Mars. With the future miniaturization of electronics components, power density and the associated challenges of electronics heat dissipation will provide new challenges. There is a challenge for improvement in modeling and analysis of thermal control systems, and for improved facilities to support testing of thermal-vacuum systems.

  11. Pilot clinic study of Project EX for smoking cessation with Spanish adolescents.

    PubMed

    Espada, José P; Gonzálvez, María T; Orgilés, Mireia; Guillén-Riquelme, Alejandro; Soto, Daniel; Sussman, Steve

    2015-06-01

    Despite efforts to prevent smoking, the prevalence of smoking in Spanish adolescents remains high. So far, there are no evidence-based smoking cessation programs for adolescents in Spain. This study describes the evaluation of Project EX, an eight-session school-based clinic smoking cessation program, with Spanish cigarette smokers 13-19 years of age, from 9 schools (four program condition schools and five control condition schools). A group-randomized controlled trial was used. There were 211 smokers at baseline (112 program group, and 99 control group). Evaluation involved an immediate pretest and posttest survey (administered five-weeks later) and six-month follow-up (after the immediate posttest). At immediate posttest, Project EX significantly reduced future nicotine dependence scores (mFTQ; p<.001), and increased intention to quit smoking (p<.001), and led to a higher previous day (prior to assessment) quit rate (p<.03). At the six-month follow-up, the percentage of quitters in the program group was 14.28%, whereas no smokers quit smoking in the control group (p<.04), and Project EX had a significant influence on future smoking expectation (p=.006) and overall level of 30-day smoking. Results for the Project EX school-based clinic are promising for adolescent smokers in Spain, although difficulties in recruitment and high attrition are of concern. Findings and limitations are discussed and suggestions for future research are suggested. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. A survey of experiments and experimental facilities for control of flexible structures

    NASA Technical Reports Server (NTRS)

    Sparks, Dean W., Jr.; Juang, Jer-Nan; Klose, Gerhard J.

    1989-01-01

    This paper presents a survey of U.S. ground experiments and facilities dedicated to the study of active control of flexible structures. The facilities will be briefly described in terms of capability, configuration, size and instrumentation. Topics on the experiments include vibration suppression, slewing and system identification. Future research directions, particularly of the NASA Langley Research Center's Controls/Structures Interaction (CSI) ground test program, will be discussed.

  13. Clinical Findings and Pain Symptoms as Potential Risk Factors for Chronic TMD: Descriptive Data and Empirically Identified Domains from the OPPERA Case-Control Study

    PubMed Central

    Ohrbach, Richard; Fillingim, Roger B.; Mulkey, Flora; Gonzalez, Yoly; Gordon, Sharon; Gremillion, Henry; Lim, Pei-Feng; Ribeiro-Dasilva, Margarete; Greenspan, Joel D.; Knott, Charles; Maixner, William; Slade, Gary

    2011-01-01

    Clinical characteristics might be associated with temporomandibular disorders (TMD) because they are antecedent risk factors that increase the likelihood of a healthy person developing the condition or because they represent signs or symptoms of either subclinical or overt TMD. In this baseline case-control study of the multisite Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA) project, 1,633 controls and 185 cases with chronic, painful TMD completed questionnaires and received clinical examinations. Odds ratios measuring association between each clinical factor and TMD were computed, with adjustment for study-site as well as age, sex, and race/ethnicity. Compared to controls, TMD cases reported more trauma, greater parafunction, more headaches and other pain disorders, more functional limitation in using the jaw, more nonpain symptoms in the facial area, more temporomandibular joint noises and jaw locking, more neural or sensory medical conditions, and worse overall medical status. They also exhibited on examination reduced jaw mobility, more joint noises, and a greater number of painful masticatory, cervical, and body muscles upon palpation. The results indicated that TMD cases differ substantially from controls across almost all variables assessed. Future analyses of follow-up data will determine whether these clinical characteristics predict increased risk for developing first-onset pain-related TMD Perspective Clinical findings from OPPERA’s baseline case-control study indicate significant differences between chronic TMD cases and controls with respect to trauma history, parafunction, other pain disorders, health status, and clinical examination data. Future analyses will examine their contribution to TMD onset. PMID:22074750

  14. Energy and economic trade offs for advanced technology subsonic aircraft

    NASA Technical Reports Server (NTRS)

    Maddalon, D. V.; Wagner, R. D.

    1976-01-01

    Changes in future aircraft technology which conserve energy are studied, along with the effect of these changes on economic performance. Among the new technologies considered are laminar-flow control, composite materials with and without laminar-flow control, and advanced airfoils. Aircraft design features studied include high-aspect-ratio wings, thickness ratio, and range. Engine technology is held constant at the JT9D level. It is concluded that wing aspect ratios of future aircraft are likely to significantly increase as a result of new technology and the push of higher fuel prices. Whereas current airplanes have been designed for AR = 7, supercritical technology and much higher fuel prices will drive aspect ratio to the AR = 9-10 range. Composite materials may raise aspect ratio to about 11-12 and practical laminar flow-control systems may further increase aspect ratio to 14 or more. Advanced technology provides significant reductions in aircraft take-off gross weight, energy consumption, and direct operating cost.

  15. Evaluating hospital design from an operations management perspective.

    PubMed

    Vos, Leti; Groothuis, Siebren; van Merode, Godefridus G

    2007-12-01

    This paper describes an evaluation method for the assessment of hospital building design from the viewpoint of operations management to assure that the building design supports the efficient and effective operating of care processes now and in the future. The different steps of the method are illustrated by a case study. In the case study an experimental design is applied to assess the effect of used logistical concepts, patient mix and technologies. The study shows that the evaluation method provides a valuable tool for the assessment of both functionality and the ability to meet future developments in operational control of a building design.

  16. Combining epidemiology and biomechanics in sports injury prevention research: a new approach for selecting suitable controls.

    PubMed

    Finch, Caroline F; Ullah, Shahid; McIntosh, Andrew S

    2011-01-01

    Several important methodological issues need to be considered when designing sports injury case-control studies. Major design goals for case-control studies include the accounting for prior injury risk exposure, and optimal definitions of both cases and suitable controls are needed to ensure this. This article reviews methodological aspects of published sports injury case-control studies, particularly with regard to the selection of controls. It argues for a new approach towards selecting controls for case-control studies that draws on an interface between epidemiological and biomechanical concepts. A review was conducted to identify sport injury case-control studies published in the peer-review literature during 1985-2008. Overall, 32 articles were identified, of which the majority related to upper or lower extremity injuries. Matching considerations were used for control selection in 16 studies. Specific mention of application of biomechanical principles in the selection of appropriate controls was absent from all studies, including those purporting to evaluate the benefits of personal protective equipment to protect against impact injury. This is a problem because it could lead to biased conclusions, as cases and controls are not fully comparable in terms of similar biomechanical impact profiles relating to the injury incident, such as site of the impact on the body. The strength of the conclusions drawn from case-control studies, and the extent to which results can be generalized, is directly influenced by the definition and recruitment of cases and appropriate controls. Future studies should consider the interface between epidemiological and biomechanical concepts when choosing appropriate controls to ensure that proper adjustment of prior exposure to injury risk is made. To provide necessary guidance for the optimal selection of controls in case-control studies of interventions to prevent sports-related impact injury, this review outlines a new case-control selection strategy that reflects the importance of biomechanical considerations, which ensures that controls are selected based on the presence of the same global injury mechanism as the cases. To summarize, the general biomechanical principles that should apply to the selection of controls in future case-control studies are as follows: (i) each control must have been exposed to the same global injury mechanism as the case, (e.g. head impact, fall onto outstretched arm); and (ii) intrinsic (individual) factors (e.g. age, sex, skill level) that might modify the person's response to the relevant biomechanical loads are adjusted when either selecting the controls or are in the analysis phase. The same considerations for control selection apply to other study designs such as matched cohort studies or case-crossover studies.

  17. Research and Development Trend of Shape Control for Cold Rolling Strip

    NASA Astrophysics Data System (ADS)

    Wang, Dong-Cheng; Liu, Hong-Min; Liu, Jun

    2017-09-01

    Shape is an important quality index of cold rolling strip. Up to now, many problems in the shape control domain have not been solved satisfactorily, and a review on the research progress in the shape control domain can help to seek new breakthrough directions. In the past 10 years, researches and applications of shape control models, shape control means, shape detection technology, and shape control system have achieved significant progress. In the aspect of shape control models, the researches in the past improve the accuracy, speed and robustness of the models. The intelligentization of shape control models should be strengthened in the future. In the aspect of the shape control means, the researches in the past focus on the roll optimization, mill type selection, process optimization, local strip shape control, edge drop control, and so on. In the future, more attention should be paid to the coordination control of both strip shape and other quality indexes, and the refinement of control objective should be strengthened. In the aspects of shape detection technology and shape control system, some new types of shape detection meters and shape control systems are developed and have successfully industrial applications. In the future, the standardization of shape detection technology and shape control system should be promoted to solve the problem of compatibility. In general, the four expected development trends of shape control for cold rolling strip in the future are intelligentization, coordination, refinement, and standardization. The proposed research provides new breakthrough directions for improving shape quality.

  18. Current and Future Research in Active Control of Lightweight, Flexible Structures Using the X-56 Aircraft

    NASA Technical Reports Server (NTRS)

    Ryan, John J.; Bosworth, John T.; Burken, John J.; Suh, Peter M.

    2014-01-01

    The X-56 Multi-Utility Technology Testbed aircraft system is a versatile experimental research flight platform. The system was primarily designed to investigate active control of lightweight flexible structures, but is reconfigurable and capable of hosting a wide breadth of research. Current research includes flight experimentation of a Lockheed Martin designed active control flutter suppression system. Future research plans continue experimentation with alternative control systems, explore the use of novel sensor systems, and experiments with the use of novel control effectors. This paper describes the aircraft system, current research efforts designed around the system, and future planned research efforts that will be hosted on the aircraft system.

  19. Impact of episodic thinking on altruism

    PubMed Central

    Yi, Richard; Pickover, Alison; Stuppy-Sullivan, Allison M.; Baker, Sydney; Landes, Reid D.

    2016-01-01

    Episodic future thinking, which refers to the use of prospective imagery to concretely imagine oneself in future scenarios, has been shown to reduce delay discounting (enhance self-control). A parallel approach, in which prospective imagery is used to concretely imagine other’s scenarios, may similarly reduce social discounting (i.e., enhance altruism). In study 1, participants engaged in episodic thinking about the self or others, in a repeated-measures design, while completing a social discounting task. Reductions in social discounting were observed as a function of episodic thinking about others, though an interaction with order was also observed. Using an independent-measures design in study 2, the effect of episodic thinking about others was replicated. Study 3 addressed a limitation of studies 1 and 2, the possibility that simply thinking about others decreased social discounting. Capitalizing on Construal Level Theory, which specifies that social distance and time in the future are both dimensions of a common psychological distance, we hypothesized that episodic future thinking should also decrease social discounting. Participants engaged in episodic future thinking or episodic present thinking, in a repeated-measures design, while completing a social discounting task. The pattern of results was similar to study 1, providing support for the notion that episodic thinking about psychologically distant outcomes (for others or in the future) reduces social discounting. Application of similar episodic thinking approaches may enhance altruism. PMID:27821875

  20. Gender differences in social network characteristics and psychological well-being among Hong Kong Chinese: the role of future time perspective and adherence to Renqing.

    PubMed

    Yeung, D Y; Fung, H H; Lang, F R

    2007-01-01

    Gender differences in social network characteristics are well documented in the literature. Socio-emotional selectivity theory emphasizes the importance of future time perception on selection of social partners whereas cultural studies stress the roles of Renqing (relationship orientation) on social interactions. This study examined the effects of future time perspective and adherence to Renqing on social network characteristics, and their associations with psychological well-being of 321 Chinese men and women, aged 28-91 years. Results showed that adherence to Renqing partially accounted for gender differences in the number of relatives, even after controlling for the effects of extraversion and structural factors. Moreover, women, but not men, with lower adherence to Renqing and more limited future time perspective were found to be happier when they had fewer close friends in their social networks.

  1. On-board multispectral classification study. Volume 2: Supplementary tasks. [adaptive control

    NASA Technical Reports Server (NTRS)

    Ewalt, D.

    1979-01-01

    The operational tasks of the onboard multispectral classification study were defined. These tasks include: sensing characteristics for future space applications; information adaptive systems architectural approaches; data set selection criteria; and onboard functional requirements for interfacing with global positioning satellites.

  2. The Status of the Quality Control in Acupuncture-Neuroimaging Studies

    PubMed Central

    Qiu, Ke; Jing, Miaomiao; Liu, Xiaoyan; Gao, Feifei; Liang, Fanrong; Zeng, Fang

    2016-01-01

    Using neuroimaging techniques to explore the central mechanism of acupuncture gains increasing attention, but the quality control of acupuncture-neuroimaging study remains to be improved. We searched the PubMed Database during 1995 to 2014. The original English articles with neuroimaging scan performed on human beings were included. The data involved quality control including the author, sample size, characteristics of the participant, neuroimaging technology, and acupuncture intervention were extracted and analyzed. The rigorous inclusion and exclusion criteria are important guaranty for the participants' homogeneity. The standard operation process of acupuncture and the stricter requirement for acupuncturist play significant role in quality control. More attention should be paid to the quality control in future studies to improve the reproducibility and reliability of the acupuncture-neuroimaging studies. PMID:27242911

  3. A systematic review and meta-analysis of willingness-to-pay values: the case of malaria control interventions.

    PubMed

    Trapero-Bertran, M; Mistry, H; Shen, J; Fox-Rushby, J

    2013-04-01

    The increasing use of willingness to pay (WTP) to value the benefits of malaria control interventions offers a unique opportunity to explore the possibility of estimating a transferable indicator of mean WTP as well as studying differences across studies. As regression estimates from individual WTP studies are often assumed to transfer across populations it also provides an opportunity to question this practice. Using a qualitative review and meta analytic methods, this article determines what has been studied and how, provides a summary mean WTP by type of intervention, considers how and why WTP estimates vary and advises on future reporting of WTP studies. WTP has been elicited mostly for insecticide-treated nets, followed by drugs for treatment. Mean WTP, including zeros, is US$2.79 for insecticide-treated nets, US$6.65 for treatment and US$2.60 for other preventive services. Controlling for a limited number of sample and design effects, results can be transferred to different countries using the value function. The main concerns are the need to account for a broader range of explanators that are study specific and the ability to transfer results into malaria contexts beyond those represented by the data. Future studies need to improve the reporting of WTP. Copyright © 2012 John Wiley & Sons, Ltd.

  4. Dust control research for SEI. [Space Exploration Initiative

    NASA Technical Reports Server (NTRS)

    Kennedy, Kriss J.; Harris, Jeffrey R.

    1992-01-01

    A study, at NASA Johnson Space Center, of dust control requirements for surface habitats has focused on identification of the dust problem, identifying dust control techniques and dust control technology areas requiring research development. This research was performed for the Surface Habitats and Construction (SHAC) technology area. Dust control consists of two problems: (1) how to keep it out of the habitat; and (2) once the habitat or airlock is contaminated with dust, how to collect it. This paper describes the dust environment, the Apollo experience and dust control methods used, future EVA operational considerations, and dust control concepts for surface habitats.

  5. Using future thinking to reduce temporal discounting: Under what circumstances are the medial temporal lobes critical?

    PubMed

    Palombo, D J; Keane, M M; Verfaellie, M

    2016-08-01

    The capacity to envision the future plays an important role in many aspects of cognition, including our ability to make optimal, adaptive choices. Past work has shown that the medial temporal lobe (MTL) is necessary for decisions that draw on episodic future thinking. By contrast, little is known about the role of the MTL in decisions that draw on semantic future thinking. Accordingly, the present study investigated whether the MTL contributes to one form of decision making, namely intertemporal choice, when such decisions depend on semantic consideration of the future. In an intertemporal choice task, participants must select either a smaller amount of money that is available in the present or a larger amount of money that would be available at a future date. Amnesic individuals with MTL damage and healthy control participants performed such a task in which, prior to making a choice, they engaged in a semantic generation exercise, wherein they generated items that they would purchase with the future reward. In experiment 1, we found that, relative to a baseline condition involving standard intertemporal choice, healthy individuals were more inclined to select a larger, later reward over a smaller, present reward after engaging in semantic future thinking. By contrast, amnesic participants were paradoxically less inclined to wait for a future reward following semantic future thinking. This finding suggests that amnesics may have had difficulty "tagging" the generated item(s) as belonging to the future. Critically, experiment 2 showed that when the generated items were presented alongside the intertemporal choices, both controls and amnesic participants shifted to more patient choices. These findings suggest that the MTL is not needed for making optimal decisions that draw on semantic future thinking as long as scaffolding is provided to support accurate time tagging. Together, these findings stand to better clarify the role of the MTL in decision making. Published by Elsevier Ltd.

  6. Virtual reality in the psychological treatment for mental health problems: An systematic review of recent evidence.

    PubMed

    Valmaggia, Lucia R; Latif, Leila; Kempton, Matthew J; Rus-Calafell, Maria

    2016-02-28

    The aim of this paper is to provide a review of controlled studies of the use of Virtual Reality in psychological treatment (VRT). Medline, PsychInfo, Embase and Web of Science were searched. Only studies comparing immersive virtual reality to a control condition were included. The search resulted in 1180 articles published between 2012 and 2015, of these, 24 were controlled studies. The reviewed studies confirm the effectiveness of VRT compared to treatment as usual, and show similar effectiveness when VRT is compared to conventional treatments. Current developments and future research are discussed. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. Loss of Control Increases Belief in Precognition and Belief in Precognition Increases Control

    PubMed Central

    Greenaway, Katharine H.; Louis, Winnifred R.; Hornsey, Matthew J.

    2013-01-01

    Every year thousands of dollars are spent on psychics who claim to “know” the future. The present research questions why, despite no evidence that humans are able to psychically predict the future, do people persist in holding irrational beliefs about precognition? We argue that believing the future is predictable increases one’s own perceived ability to exert control over future events. As a result, belief in precognition should be particularly strong when people most desire control–that is, when they lack it. In Experiment 1 (N = 87), people who were experimentally induced to feel low in control reported greater belief in precognition than people who felt high in control. Experiment 2 (N = 53) investigated whether belief in precognition increases perceived control. Consistent with this notion, providing scientific evidence that precognition is possible increased feelings of control relative to providing scientific evidence that precognition was not possible. Experiment 3 (N = 132) revealed that when control is low, believing in precognition helps people to feel in control once more. Prediction therefore acts as a compensatory mechanism in times of low control. The present research provides new insights into the psychological functions of seemingly irrational beliefs, like belief in psychic abilities. PMID:23951136

  8. Formulation of advanced consumables management models: Executive summary. [modeling spacecraft environmental control, life support, and electric power supply systems

    NASA Technical Reports Server (NTRS)

    Daly, J. K.; Torian, J. G.

    1979-01-01

    An overview of studies conducted to establish the requirements for advanced subsystem analytical tools is presented. Modifications are defined for updating current computer programs used to analyze environmental control, life support, and electric power supply systems so that consumables for future advanced spacecraft may be managed.

  9. Cardiovascular and Cerebrovascular Control on Return from ISS

    NASA Technical Reports Server (NTRS)

    Hughson, Richard Lee; Shoemaker, Joel Kevin; Blaber, Andrew Philip; Arbeille, Philippe; Greaves, Danielle Kathleen

    2008-01-01

    Cardiovascular and Cerebrovascular Control on Return from ISS (CCISS) will study the effects of long-duration spaceflight on crew members' heart functions and their blood vessels that supply the brain. Learning more about the cardiovascular and cerebrovascular systems could lead to specific countermeasures that might better protect future space travelers. This experiment is collaborative with the Canadian Space Agency.

  10. Space shuttle flying qualities and criteria assessment

    NASA Technical Reports Server (NTRS)

    Myers, T. T.; Johnston, D. E.; Mcruer, Duane T.

    1987-01-01

    Work accomplished under a series of study tasks for the Flying Qualities and Flight Control Systems Design Criteria Experiment (OFQ) of the Shuttle Orbiter Experiments Program (OEX) is summarized. The tasks involved review of applicability of existing flying quality and flight control system specification and criteria for the Shuttle; identification of potentially crucial flying quality deficiencies; dynamic modeling of the Shuttle Orbiter pilot/vehicle system in the terminal flight phases; devising a nonintrusive experimental program for extraction and identification of vehicle dynamics, pilot control strategy, and approach and landing performance metrics, and preparation of an OEX approach to produce a data archive and optimize use of the data to develop flying qualities for future space shuttle craft in general. Analytic modeling of the Orbiter's unconventional closed-loop dynamics in landing, modeling pilot control strategies, verification of vehicle dynamics and pilot control strategy from flight data, review of various existent or proposed aircraft flying quality parameters and criteria in comparison with the unique dynamic characteristics and control aspects of the Shuttle in landing; and finally a summary of conclusions and recommendations for developing flying quality criteria and design guides for future Shuttle craft.

  11. Re-examination of sea lamprey control policies for the St. Marys River: Completion of an adaptive management cycle

    USGS Publications Warehouse

    Jones, Michael L.; Brenden, Travis O.; Irwin, Brian J.

    2015-01-01

    The St. Marys River (SMR) historically has been a major producer of sea lampreys (Petromyzon marinus) in the Laurentian Great Lakes. In the early 2000s, a decision analysis (DA) project was conducted to evaluate sea lamprey control policies for the SMR; this project suggested that an integrated policy of trapping, sterile male releases, and Bayluscide treatment was the most cost-effective policy. Further, it concluded that formal assessment of larval sea lamprey abundance and distribution in the SMR would be valuable for future evaluation of control strategies. We updated this earlier analysis, adding information from annual larval assessments conducted since 1999 and evaluating additional control policies. Bayluscide treatments continued to be critical for sea lamprey control, but high recruitment compensation minimized the effectiveness of trapping and sterile male release under current feasible ranges. Because Bayluscide control is costly, development of strategies to enhance trapping success remains a priority. This study illustrates benefits of an adaptive management cycle, wherein models inform decisions, are updated based on learning achieved from those decisions, and ultimately inform future decisions.

  12. Implications of alternative assumptions regarding future air pollution control in scenarios similar to the Representative Concentration Pathways

    NASA Astrophysics Data System (ADS)

    Chuwah, Clifford; van Noije, Twan; van Vuuren, Detlef P.; Hazeleger, Wilco; Strunk, Achim; Deetman, Sebastiaan; Beltran, Angelica Mendoza; van Vliet, Jasper

    2013-11-01

    The uncertain, future development of emissions of short-lived trace gases and aerosols forms a key factor for future air quality and climate forcing. The Representative Concentration Pathways (RCPs) only explore part of this range as they all assume that worldwide ambitious air pollution control policies will be implemented. In this study, we explore how different assumptions on future air pollution policy and climate policy lead to different concentrations of air pollutants for a set of RCP-like scenarios developed using the IMAGE model. These scenarios combine low and high air pollution variants of the scenarios with radiative forcing targets in 2100 of 2.6 W m-2 and 6.0 W m-2. Simulations using the global atmospheric chemistry and transport model TM5 for the present-day climate show that both climate mitigation and air pollution control policies have large-scale effects on pollutant concentrations, often of similar magnitude. If no further air pollution policies would be implemented, pollution levels could be considerably higher than in the RCPs, especially in Asia. Air pollution control measures could significantly reduce the warming by tropospheric ozone and black carbon and the cooling by sulphate by 2020, and in the longer term contribute to enhanced warming by methane. These effects tend to cancel each other on a global scale. According to our estimates the effect of the worldwide implementation of air pollution control measures on the total global mean direct radiative forcing in 2050 is +0.09 W m-2 in the 6.0 W m-2 scenario and -0.16 W m-2 in the 2.6 W m-2 scenario.

  13. Guilt and Effortful Control: Two Mechanisms that Prevent Disruptive Developmental Trajectories

    PubMed Central

    Kochanska, Grazyna; Barry, Robin A.; Jimenez, Natasha B.; Hollatz, Amanda L.; Woodard, Jarilyn

    2009-01-01

    Children's guilt associated with transgressions and their capacity for effortful control are both powerful forces that inhibit disruptive conduct. We examined how guilt and effortful control, repeatedly observed from toddler to preschool age, jointly predict children's disruptive outcomes in two multi-method multi-trait longitudinal studies (N's 57 and 99). Disruptive outcomes were rated by mothers at 73 months (Study 1) and mothers, fathers, and teachers at 52 and 67 months (Study 2). In both studies, guilt moderated effects of effortful control: For highly guilt-prone children, variations in effortful control were unrelated to future disruptive outcomes, but for children who were less guilt prone, effortful control predicted such outcomes. Guilt may inhibit transgressions through an automatic response due to negative arousal triggered by memories of past wrongdoing, regardless of child capacity for deliberate inhibition. Effortful control that engages a deliberate restraint may offset risk for disruptive conduct conferred by low guilt. PMID:19634978

  14. InternationaL cross-sectIonAl and longItudinal assessment on aSthma cONtrol in European adult patients - the LIAISON study protocol

    PubMed Central

    2013-01-01

    Background According to international guidelines, the goal of asthma management is to achieve and maintain control of the disease, which can be assessed using composite measures. Prospective studies are required to determine how these measures are associated with asthma outcomes and/or future risk. The ‘InternationaL cross-sectIonAl and longItudinal assessment on aSthma cONtrol (LIAISON)’ observational study has been designed to evaluate asthma control and its determinants, including components of asthma management. Methods/design The LIAISON study will be conducted in 12 European countries and comprises a cross-sectional phase and a 12-month prospective phase. Both phases will aim at assessing asthma control (six-item Asthma Control Questionnaire, ACQ), asthma-related quality of life (Mini Asthma Quality of Life Questionnaire, Mini-AQLQ), risk of non-adherence to treatment (four-item Morisky Medication Adherence Scale, MMAS-4), potential reasons for poor control, treatment strategies and associated healthcare costs. The cross-sectional phase will recruit > 8,000 adult patients diagnosed with asthma for at least 6 months and receiving the same asthma treatment in the 4 weeks before enrolment. The prospective phase will include all patients with uncontrolled/poorly controlled asthma at the initial visit to assess the proportion reaching control during follow-up and to examine predictors of future risk. Visits will take place after 3, 6 and 12 months. Discussion The LIAISON study will provide important information on the prevalence of asthma control and on the quality of life in a broad spectrum of real-life patient populations from different European countries and will also contribute to evaluate differences in management strategies and their impact on healthcare costs over 12 months of observation. Trial registration ClinicalTrials.gov identifier, NCT01567280. PMID:23530817

  15. A naturalistic study of railway controllers.

    PubMed

    Farrington-Darby, T; Wilson, John R; Norris, B J; Clarke, Theresa

    There is an increasing prevalence for work to be analysed through naturalistic study, especially using ethnographically derived methods of enquiry and qualitative field research. The relatively unexplored domain of railway control (in comparison to signalling) in the UK is described in terms of features derived from observations and semi-structured interviews. In addition, task diagrams (a technique taken from the Applied Cognitive Task Analysis toolkit) are used to represent controllers' core elements of work, i.e. to manage events or incidents, and to identify the challenging steps in the process. The work features identified, the task diagrams, and the steps identified as challenging form a basis from which future ergonomics studies on railway controllers in the UK will be carried out.

  16. Traffic Predictive Control: Case Study and Evaluation

    DOT National Transportation Integrated Search

    2017-06-26

    This project developed a quantile regression method for predicting future traffic flow at a signalized intersection by combining both historical and real-time data. The algorithm exploits nonlinear correlations in historical measurements and efficien...

  17. Study of Membrane Reflector Technology

    NASA Technical Reports Server (NTRS)

    Knapp, K.; Hedgepeth, J.

    1979-01-01

    Very large reflective surfaces are required by future spacecraft for such purposes as solar energy collection, antenna surfaces, thermal control, attitude and orbit control with solar pressure, and solar sailing. The performance benefits in large membrane reflector systems, which may be derived from an advancement of this film and related structures technology, are identified and qualified. The results of the study are reported and summarized. Detailed technical discussions of various aspects of the study are included in several separate technical notes which are referenced.

  18. Neural control of the kidney: past, present, and future.

    PubMed

    DiBona, Gerald F

    2003-03-01

    This article provides a chronological perspective on the development of knowledge concerning the neural control of renal function and is divided into three parts: the past, the present, and the future.

  19. Substance abuse prevention intervention research with Hispanic populations.

    PubMed

    Castro, Felipe González; Barrera, Manuel; Pantin, Hilda; Martinez, Charles; Felix-Ortiz, Maria; Rios, Rebeca; Lopez, Vera A; Lopez, Cristy

    2006-09-01

    Selected studies with specific relevance to substance abuse prevention interventions with Hispanic youth and families were examined to identify prior findings and emerging issues that may guide the design of future substance abuse prevention intervention research and its implementation with Hispanic populations. The origins of prevention research and role of risk and protective factors are examined, including culturally-specific risk and protective factors for Hispanic populations. Correlational studies, non-experimental interventions, and randomized controlled trials were examined for the period of 1974-2003. The literature search yielded 15 articles selected for this review that exhibited adequate methodological rigor. An added search for more recent studies identified three additional articles, for a total of 18 prevention intervention articles that were reviewed. Theoretical and methodological issues and recommendations are presented for future research aimed at improving the efficacy and effectiveness of future prevention intervention studies and their cultural relevance for Hispanic populations.

  20. Infants Prospectively Control Reaching Based on the Difficulty of Future Actions: To What Extent Can Infants' Multiple-Step Actions Be Explained by Fitts' Law?

    ERIC Educational Resources Information Center

    Gottwald, Janna M.; De Bortoli Vizioli, Aurora; Lindskog, Marcus; Nyström, Pär; L. Ekberg, Therese; von Hofsten, Claes; Gredebäck, Gustaf

    2017-01-01

    Prospective motor control, a key element of action planning, is the ability to adjust one's actions with respect to task demands and action goals in an anticipatory manner. The current study investigates whether 14-month-olds can prospectively control their reaching actions based on the difficulty of the subsequent action. We used a reach-to-place…

  1. Implications of alternative assumptions regarding future air pollution control in RCP-like scenarios

    NASA Astrophysics Data System (ADS)

    Chuwah, Clifford; van Noije, Twan; van Vuuren, Detlef; Hazeleger, Wilco; Strunk, Achim; Deetman, Sebastiaan; Mendoza Beltran, Angelica; van Vliet, Jasper

    2013-04-01

    Estimation of future emissions of short-lived trace gases and aerosols from human activities is a main source of uncertainty in projections of future air quality and climate forcing. The Representative Concentration Pathways (RCPs), however, all assume that worldwide ambitious air pollution control policies will be implemented in the coming decades. In this study, we therefore explore the consequences of four alternative emission scenarios generated using the IMAGE integrated assessment model following the methods used to generate the RCPs. These scenarios combine low and high air pollution variants of the scenarios with radiative forcing targets in 2100 of 2.6 W/m2 and 6.0 W/m2 (the high air pollution variants assume no improvement in emission factors, representing a hypothetical upper end of emission levels). Analysis using the global atmospheric chemistry and transport model TM5 shows that climate mitigation and air pollution control policy variants studied here have similar large-scale effects on the concentrations of ozone and black carbon; the impact of climate policy, however, has a stronger impact on sulphate concentrations. Air pollution control measures could significantly reduce the warming by tropospheric ozone and black carbon and the cooling by sulphate already in 2020, and on the longer term contribute to enhanced warming by methane. These effects tend to cancel each other at the global scale. According to our estimates the effect of the worldwide implementation of air pollution control measures on the total global mean direct radiative forcing in 2050 is +0.09 W/m2 in the 6.0 W/m2 scenario and -0.16 W/m2 in the 2.6 W/m2 scenario.

  2. Concordance of opinions between patients and physicians and their relationship with symptomatic control and future risk in patients with moderate-severe asthma.

    PubMed

    Crespo-Lessmann, Astrid; Plaza, Vicente; González-Barcala, Francisco-Javier; Fernández-Sánchez, Toni; Sastre, Joaquín

    2017-01-01

    Differences between the opinions of patients and physicians on the impact of asthma are common. We hypothesised that patient-physician discordance may negatively affect asthma outcome. A total of 2902 patients (61% women, mean age 47 years) with moderate-severe asthma and 231 physicians participated in a prospective study. At the baseline visit, data on demographics, clinical variables, degree of asthma control according to the Asthma Control Test (ACT), basic spirometry and the Hospital Anxiety and Depression Scale (HADS) were collected and an ad hoc questionnaire was completed that allowed the degree of concordance between doctors and patients to be assessed. A scheduled telephone call after 3 months was used to elicit the ACT score and the future risk of asthma. At the final visit at 6 months, the following data were recorded: ACT score, spirometry, HADS score and an ad hoc questionnaire to assess the agreement between the doctor and the patient. Changes in study variables according to patient-physician concordance or discordance were analysed. The rate of patient-physician discordance was 27.2%, with overestimation of disease impact by the physician in 12.3% and underestimation in 14.9%. Patient-physician opinion discordance, particularly in the case of physicians underestimating the impact of asthma, showed worse results with statistically significant differences in ACT score, a higher percentage of patients with poor asthma control and lower HADS scores. The need for hospital and emergency department admissions was also higher. Patient-physician opinion discordance may be contributing to lower symptomatic control and increased future risk, with a higher impact when physicians underestimate the impact of asthma on their patients.

  3. Does the perception that God controls health outcomes matter for health behaviors?

    PubMed

    Karvinen, Kristina H; Carr, Lucas J

    2014-04-01

    The purpose of this study was to examine the associations between God Locus of Health Control, health behaviors, and beliefs utilizing a cross-sectional online survey (N = 549). Results indicated that God Locus of Health Control was correlated with alcohol use, physical activity, perceived risk of chronic disease, and beliefs that poor health behaviors contribute to chronic disease (all p values < .05). Multiple regression analyses including covariates and other locus of control variables revealed that God Locus of Health Control was only an independent correlate of the belief that physical inactivity contributed to chronic disease. Insights from this study may be important for future faith-based health behavior change interventions.

  4. External-Stimuli-Assisted Control over Assemblies of Plasmonic Metals.

    PubMed

    Watanabe, Kanako; Kuroda, Kotaro; Nagao, Daisuke

    2018-05-15

    Assembly of plasmonic nanoparticles (NPs) in suspensions is a promising approach for the control of optical and sensing properties that depend on the assembled states of plasmonic NPs. This review focuses on the controlling methods to assemble the NP via external stimuli such as pH, temperature, light, magnetic field, and electric field. External stimuli are introduced as powerful tools to assemble the NPs because of various operational factors, such as the intensity, application time, and frequency, which can be employed. In addition to a summary of recent studies on the controlling methods, a future study on the reversible control over assembled states of the plasmonic NPs via external stimuli is proposed.

  5. Parental loss, trusting relationship with current caregivers, and psychosocial adjustment among children affected by AIDS in China.

    PubMed

    Zhao, Junfeng; Li, Xiaoming; Barnett, Douglas; Lin, Xiuyun; Fang, Xiaoyi; Zhao, Guoxiang; Naar-King, Sylvie; Stanton, Bonita

    2011-08-01

    The objective of this study was to examine the relationship between parental loss, trusting relationship with current caregivers, and psychosocial adjustment among children affected by AIDS in China. In this study, cross-sectional data were collected from 755 AIDS orphans (296 double orphans and 459 single orphans), 466 vulnerable children living with HIV-infected parents, and 404 comparison children in China. The trusting relationship with current caregivers was measured with a 15-item scale (Cronbach's α = 0.84) modified from the Trusting Relationship Questionnaire developed by Mustillo et al. in 2005 (Quality of relationships between youth and community service providers: Reliability and validity of the trusting relationship questionnaire. Journal of Child and Family Studies, 14, 577-590). The psychosocial measures include rule compliance/acting out, anxiety/withdrawal, peer social skills, school interest, depressive symptoms, loneliness, self-esteem, future expectation, hopefulness about future, and perceived control over the future. Group mean comparisons using analysis of variance suggested a significant association (p < 0.0001) between the trusting relationship with current caregivers and all the psychosocial measures, except anxiety and depression. These associations remained significant in General Linear Model analysis, controlling for children's gender, age, family socioeconomic status, orphan status (orphans, vulnerable children, and comparison children), and appropriate interaction terms among factor variables. The findings in the current study support the global literature on the importance of attachment relationship with caregivers in promoting children's psychosocial development. Future prevention intervention efforts to improve AIDS orphans' psychosocial well-being will need to take into consideration the quality of the child's attachment relationships with current caregivers and help their current caregivers to improve the quality of care for these children. Future study is needed to explore the possible reasons for the lack of association between a trusting relationship and some internalizing symptoms such as anxiety and depression among children affected by HIV/AIDS.

  6. A reusable rocket engine intelligen control

    NASA Technical Reports Server (NTRS)

    Merrill, Walter C.; Lorenzo, Carl F.

    1988-01-01

    An intelligent control system for reusable space propulsion systems for future launch vehicles is described. The system description includes a framework for the design. The framework consists of an execution level with high-speed control and diagnostics, and a coordination level which marries expert system concepts with traditional control. A comparison is made between air breathing and rocket engine control concepts to assess the relative levels of development and to determine the applicability of air breathing control concepts to future reusable rocket engine systems.

  7. A reusable rocket engine intelligent control

    NASA Technical Reports Server (NTRS)

    Merrill, Walter C.; Lorenzo, Carl F.

    1988-01-01

    An intelligent control system for reusable space propulsion systems for future launch vehicles is described. The system description includes a framework for the design. The framework consists of an execution level with high-speed control and diagnostics, and a coordination level which marries expert system concepts with traditional control. A comparison is made between air breathing and rocket engine control concepts to assess the relative levels of development and to determine the applicability of air breathing control concepts ot future reusable rocket engine systems.

  8. Local and Remote Cooperation With Virtual and Robotic Agents: A P300 BCI Study in Healthy and People Living With Spinal Cord Injury.

    PubMed

    Tidoni, Emmanuele; Abu-Alqumsan, Mohammad; Leonardis, Daniele; Kapeller, Christoph; Fusco, Gabriele; Guger, Cristoph; Hintermuller, Cristoph; Peer, Angelika; Frisoli, Antonio; Tecchia, Franco; Bergamasco, Massimo; Aglioti, Salvatore Maria

    2017-09-01

    The development of technological applications that allow people to control and embody external devices within social interaction settings represents a major goal for current and future brain-computer interface (BCI) systems. Prior research has suggested that embodied systems may ameliorate BCI end-user's experience and accuracy in controlling external devices. Along these lines, we developed an immersive P300-based BCI application with a head-mounted display for virtual-local and robotic-remote social interactions and explored in a group of healthy participants the role of proprioceptive feedback in the control of a virtual surrogate (Study 1). Moreover, we compared the performance of a small group of people with spinal cord injury (SCI) to a control group of healthy subjects during virtual and robotic social interactions (Study 2), where both groups received a proprioceptive stimulation. Our attempt to combine immersive environments, BCI technologies and neuroscience of body ownership suggests that providing realistic multisensory feedback still represents a challenge. Results have shown that healthy and people living with SCI used the BCI within the immersive scenarios with good levels of performance (as indexed by task accuracy, optimizations calls and Information Transfer Rate) and perceived control of the surrogates. Proprioceptive feedback did not contribute to alter performance measures and body ownership sensations. Further studies are necessary to test whether sensorimotor experience represents an opportunity to improve the use of future embodied BCI applications.

  9. Choosing Money over Drugs: The Neural Underpinnings of Difficult Choice in Chronic Cocaine Users.

    PubMed

    Wesley, Michael J; Lohrenz, Terry; Koffarnus, Mikhail N; McClure, Samuel M; De La Garza, Richard; Salas, Ramiro; Thompson-Lake, Daisy G Y; Newton, Thomas F; Bickel, Warren K; Montague, P Read

    2014-01-01

    Addiction is considered a disorder that drives individuals to choose drugs at the expense of healthier alternatives. However, chronic cocaine users (CCUs) who meet addiction criteria retain the ability to choose money in the presence of the opportunity to choose cocaine. The neural mechanisms that differentiate CCUs from non-cocaine using controls (Controls) while executing these preferred choices remain unknown. Thus, therapeutic strategies aimed at shifting preferences towards healthier alternatives remain somewhat uninformed. This study used BOLD neuroimaging to examine brain activity as fifty CCUs and Controls performed single- and cross-commodity intertemporal choice tasks for money and/or cocaine. Behavioral analyses revealed preferences for each commodity type. Imaging analyses revealed the brain activity that differentiated CCUs from Controls while choosing money over cocaine. We observed that CCUs devalued future commodities more than Controls. Choices for money as opposed to cocaine correlated with greater activity in dorsal striatum of CCUs, compared to Controls. In addition, choices for future money as opposed to immediate cocaine engaged the left dorsolateral prefrontal cortex (DLPFC) of CCUs more than Controls. These data suggest that the ability of CCUs to execute choices away from cocaine relies on activity in the dorsal striatum and left DLPFC.

  10. Lessons learned from a practice-based, multi-site intervention study with nurse participants

    PubMed Central

    Friese, Christopher R.; Mendelsohn-Victor, Kari; Ginex, Pamela; McMahon, Carol M.; Fauer, Alex J.; McCullagh, Marjorie C.

    2016-01-01

    Purpose To identify challenges and solutions to the efficient conduct of a multi-site, practice-based randomized controlled trial to improve nurses’ adherence to personal protective equipment use in ambulatory oncology settings. Design The Drug Exposure Feedback and Education for Nurses’ Safety (DEFENS) study is a clustered, randomized, controlled trial. Participating sites are randomized to web-based feedback on hazardous drug exposures in the sites plus tailored messages to address barriers versus a control intervention of a web-based continuing education video. Approach The study principal investigator, the study coordinator, and two site leaders identified challenges to study implementation and potential solutions, plus potential methods to prevent logistical challenges in future studies. Findings Noteworthy challenges included variation in human subjects protection policies, grants and contracts budgeting, infrastructure for nursing-led research, and information technology variation. Successful strategies included scheduled web conferences, site-based study champions, site visits by the principal investigator, and centrally-based document preparation. Strategies to improve efficiency in future studies include early and continued engagement with contract personnel in sites, and proposed changes to the common rule concerning human subjects. The DEFENS study successfully recruited 393 nurses across 12 sites. To date, 369 have completed surveys and 174 nurses have viewed educational materials. Conclusions Multi-site studies of nursing personnel are rare and challenging to existing infrastructure. These barriers can be overcome with strong engagement and planning. Clinical Relevance Leadership engagement, onsite staff support, and continuous communication can facilitate successful recruitment to a workplace-based randomized, controlled behavioral trial. PMID:28098951

  11. Automation in future air traffic management: effects of decision aid reliability on controller performance and mental workload.

    PubMed

    Metzger, Ulla; Parasuraman, Raja

    2005-01-01

    Future air traffic management concepts envisage shared decision-making responsibilities between controllers and pilots, necessitating that controllers be supported by automated decision aids. Even as automation tools are being introduced, however, their impact on the air traffic controller is not well understood. The present experiments examined the effects of an aircraft-to-aircraft conflict decision aid on performance and mental workload of experienced, full-performance level controllers in a simulated Free Flight environment. Performance was examined with both reliable (Experiment 1) and inaccurate automation (Experiment 2). The aid improved controller performance and reduced mental workload when it functioned reliably. However, detection of a particular conflict was better under manual conditions than under automated conditions when the automation was imperfect. Potential or actual applications of the results include the design of automation and procedures for future air traffic control systems.

  12. The impacts of climate, land use, and demography on fires during the 21st century simulated by CLM-CN

    NASA Astrophysics Data System (ADS)

    Kloster, S.; Mahowald, N. M.; Randerson, J. T.; Lawrence, P. J.

    2012-01-01

    Landscape fires during the 21st century are expected to change in response to multiple agents of global change. Important controlling factors include climate controls on the length and intensity of the fire season, fuel availability, and fire management, which are already anthropogenically perturbed today and are predicted to change further in the future. An improved understanding of future fires will contribute to an improved ability to project future anthropogenic climate change, as changes in fire activity will in turn impact climate. In the present study we used a coupled-carbon-fire model to investigate how changes in climate, demography, and land use may alter fire emissions. We used climate projections following the SRES A1B scenario from two different climate models (ECHAM5/MPI-OM and CCSM) and changes in population. Land use and harvest rates were prescribed according to the RCP 45 scenario. In response to the combined effect of all these drivers, our model estimated, depending on our choice of climate projection, an increase in future (2075-2099) fire carbon emissions by 17 and 62% compared to present day (1985-2009). The largest increase in fire emissions was predicted for Southern Hemisphere South America for both climate projections. For Northern Hemisphere Africa, a region that contributed significantly to the global total fire carbon emissions, the response varied between a decrease and an increase depending on the climate projection. We disentangled the contribution of the single forcing factors to the overall response by conducting an additional set of simulations in which each factor was individually held constant at pre-industrial levels. The two different projections of future climate change evaluated in this study led to increases in global fire carbon emissions by 22% (CCSM) and 66% (ECHAM5/MPI-OM). The RCP 45 projection of harvest and land use led to a decrease in fire carbon emissions by -5%. The RCP 26 and RCP 60 harvest and landuse projections caused decreases around -20%. Changes in human ignition led to an increase of 20%. When we also included changes in fire management efforts to suppress fires in densely populated areas, global fire carbon emission decreased by -6% in response to changes in population density. We concluded from this study that changes in fire emissions in the future are controlled by multiple interacting factors. Although changes in climate led to an increase in future fire emissions this could be globally counterbalanced by coupled changes in land use, harvest, and demography.

  13. A systematic review of studies evaluating diffusion and dissemination of selected cancer control interventions.

    PubMed

    Ellis, Peter; Robinson, Paula; Ciliska, Donna; Armour, Tanya; Brouwers, Melissa; O'Brien, Mary Ann; Sussman, Jonathan; Raina, Parminder

    2005-09-01

    With this review, the authors sought to determine what strategies have been evaluated (including the outcomes assessed) to disseminate cancer control interventions that promote the uptake of behavior change. Five topic areas along the cancer care continuum (smoking cessation, healthy diet, mammography, cervical cancer screening, and control of cancer pain) were selected to be representative. A systematic review was conducted of primary studies evaluating dissemination of a cancer control intervention. Thirty-one studies were identified that evaluated dissemination strategies in the 5 topic areas. No strong evidence currently exists to recommend any one dissemination strategy as effective in promoting the uptake of cancer control interventions. The authors conclude that there is a strong need for more research into dissemination of cancer control interventions. Future research should consider methodological issues such as the most appropriate study design and outcomes to be evaluated. (c) 2005 APA, all rights reserved

  14. Realistic Control Perceptions, Age, and Gender as Moderators of the Relationship between Victimization and Hope in Children.

    ERIC Educational Resources Information Center

    Oskin, Deborah L.

    This study examined age, gender, and subjects' realistic perceptions of control as potential moderators of the effect of community violence exposure (victimization and witnessing) on children's hopes for the future. Home interviews were conducted with 99 children ages 8 to 12 years living in high violence areas of a large southeastern city.…

  15. Medical Conditions in the First Years of Life Associated with Future Diagnosis of ASD in Children

    ERIC Educational Resources Information Center

    Alexeeff, Stacey E.; Yau, Vincent; Qian, Yinge; Davignon, Meghan; Lynch, Frances; Crawford, Phillip; Davis, Robert; Croen, Lisa A.

    2017-01-01

    This study examines medical conditions diagnosed prior to the diagnosis of autism spectrum disorder (ASD). Using a matched case control design with 3911 ASD cases and 38,609 controls, we found that 38 out of 79 medical conditions were associated with increased ASD risk. Developmental delay, mental health, and neurology conditions had the strongest…

  16. Efficient multi-scenario Model Predictive Control for water resources management with ensemble streamflow forecasts

    NASA Astrophysics Data System (ADS)

    Tian, Xin; Negenborn, Rudy R.; van Overloop, Peter-Jules; María Maestre, José; Sadowska, Anna; van de Giesen, Nick

    2017-11-01

    Model Predictive Control (MPC) is one of the most advanced real-time control techniques that has been widely applied to Water Resources Management (WRM). MPC can manage the water system in a holistic manner and has a flexible structure to incorporate specific elements, such as setpoints and constraints. Therefore, MPC has shown its versatile performance in many branches of WRM. Nonetheless, with the in-depth understanding of stochastic hydrology in recent studies, MPC also faces the challenge of how to cope with hydrological uncertainty in its decision-making process. A possible way to embed the uncertainty is to generate an Ensemble Forecast (EF) of hydrological variables, rather than a deterministic one. The combination of MPC and EF results in a more comprehensive approach: Multi-scenario MPC (MS-MPC). In this study, we will first assess the model performance of MS-MPC, considering an ensemble streamflow forecast. Noticeably, the computational inefficiency may be a critical obstacle that hinders applicability of MS-MPC. In fact, with more scenarios taken into account, the computational burden of solving an optimization problem in MS-MPC accordingly increases. To deal with this challenge, we propose the Adaptive Control Resolution (ACR) approach as a computationally efficient scheme to practically reduce the number of control variables in MS-MPC. In brief, the ACR approach uses a mixed-resolution control time step from the near future to the distant future. The ACR-MPC approach is tested on a real-world case study: an integrated flood control and navigation problem in the North Sea Canal of the Netherlands. Such an approach reduces the computation time by 18% and up in our case study. At the same time, the model performance of ACR-MPC remains close to that of conventional MPC.

  17. Aspirations, Expectations and Delinquency: The Moderating Effect of Impulse Control.

    PubMed

    Mahler, Alissa; Simmons, Cortney; Frick, Paul J; Steinberg, Laurence; Cauffman, Elizabeth

    2017-07-01

    Although prior research finds a robust link between delinquent behavior and expectations, or an adolescent's perceived likelihood of obtaining one's future goals, fewer studies have evaluated aspirations, or the perceived importance of achieving one's goals. In addition, few studies consider how individual traits such as impulsivity affect the degree to which expectations and aspirations motivate or deter delinquent behavior. We contribute to this body of research by evaluating the independent effects of expectations and aspirations, and the aspiration-expectation gap (i.e., strain) on delinquent behavior during the year following an adolescent's first arrest using a large (N = 1117), racially/ethnically diverse sample of male adolescents (46.55% Latino, 35.81% Black, 14.95% White, and 2.69% Other race). In addition, we considered how impulse control interacts with expectations, aspirations, and strain to motivate behavior. Our results indicated that both aspirations, expectations and strain uniquely influence criminal behavior. Importantly, aspirations interacted with impulse control, such that aspirations affected delinquency only among youth with higher impulse control. Our findings suggest that aspirations may only influence behavior if youth also have the psychosocial capabilities to consider their future aspirations when behaving in the present.

  18. Model learning for robot control: a survey.

    PubMed

    Nguyen-Tuong, Duy; Peters, Jan

    2011-11-01

    Models are among the most essential tools in robotics, such as kinematics and dynamics models of the robot's own body and controllable external objects. It is widely believed that intelligent mammals also rely on internal models in order to generate their actions. However, while classical robotics relies on manually generated models that are based on human insights into physics, future autonomous, cognitive robots need to be able to automatically generate models that are based on information which is extracted from the data streams accessible to the robot. In this paper, we survey the progress in model learning with a strong focus on robot control on a kinematic as well as dynamical level. Here, a model describes essential information about the behavior of the environment and the influence of an agent on this environment. In the context of model-based learning control, we view the model from three different perspectives. First, we need to study the different possible model learning architectures for robotics. Second, we discuss what kind of problems these architecture and the domain of robotics imply for the applicable learning methods. From this discussion, we deduce future directions of real-time learning algorithms. Third, we show where these scenarios have been used successfully in several case studies.

  19. Genomic Studies in Soybean: Toward Understanding Seed Oil and Protein Production

    USDA-ARS?s Scientific Manuscript database

    The molecular mechanisms that influence soybean seed composition are not well understood. Insight into the genetic controls involved in these traits is important for future soybean improvement. In this study, we identified candidate genes at the major soybean protein quantitative trait locus at Link...

  20. Is the Belief in Meritocracy Palliative for Members of Low Status Groups? Evidence for a Benefit for Self-Esteem and Physical Health via Perceived Control

    PubMed Central

    McCoy, Shannon K.; Wellman, Joseph D.; Cosley, Brandon; Saslow, Laura; Epel, Elissa

    2013-01-01

    Consensually held ideologies may serve as the cultural “glue” that justifies hierarchical status differences in society (e.g. Augustinos, 1998). Yet to be effective these beliefs need to be embraced by low-status groups. Why would members of low-status groups endorse beliefs that justify their relative disadvantage? We propose that members of low-status groups in the United States may benefit from some system-justifying beliefs (such as the belief in meritocracy) to the extent that these beliefs emphasize the perception of control over future outcomes. In 2 studies, among women, lower-SES women, and women of color, we found a positive relationship between the belief in meritocracy and well-being (self-esteem and physical health) that was mediated by perceived control. Members of low-status groups may benefit from some system-justifying beliefs to the extent that these beliefs, like the belief in meritocracy, emphasize the perception of control over future outcomes. PMID:24039310

  1. Controls, health assessment, and conditional monitoring for large, reusable, liquid rocket engines

    NASA Technical Reports Server (NTRS)

    Cikanek, H. A., III

    1986-01-01

    Past and future progress in the performance of control systems for large, liquid rocket engines typified such as current state-of-the-art, the Shuttle Main Engine (SSME), is discussed. Details of the first decade of efforts, which culminates in the F-1 and J-2 Saturn engines control systems, are traced, noting problem modes and improvements which were implemented to realize the SSME. Future control system designs, to accommodate the requirements of operation of engines for a heavy lift launch vehicle, an orbital transfer vehicle and the aerospace plane, are summarized. Generic design upgrades needed include an expanded range of fault detection, maintenance as-needed instead of as-scheduled, reduced human involvement in engine operations, and increased control of internal engine states. Current NASA technology development programs aimed at meeting the future control system requirements are described.

  2. Human-Centered Technologies and Procedures for Future Air Traffic Management

    NASA Technical Reports Server (NTRS)

    Smith, Philip; Woods, David; McCoy, Elaine; Billings, Charles; Sarter, Nadine; Denning, Rebecca; Dekker, Sidney

    1997-01-01

    The use of various methodologies to predict the impact of future Air Traffic Management (ATM) concepts and technologies is explored. The emphasis has been on the importance of modeling coordination and cooperation among multiple agents within this system, and on understanding how the interactions among these agents will be influenced as new roles, responsibilities, procedures and technologies are introduced. To accomplish this, we have been collecting data on performance under the current air traffic management system, identifying critical problem areas and looking for examples suggestive of general approaches for solving such problems. Using the results of these field studies, we have developed a set of concrete scenarios centered around future designs, and have studied performance in these scenarios with a set of 40 controllers, dispatchers, pilots and traffic managers.

  3. ECLSS Integration Analysis: Advanced ECLSS Subsystem and Instrumentation Technology Study for the Space Exploration Initiative

    NASA Technical Reports Server (NTRS)

    1990-01-01

    In his July 1989 space policy speech, President Bush proposed a long range continuing commitment to space exploration and development. Included in his goals were the establishment of permanent lunar and Mars habitats and the development of extended duration space transportation. In both cases, a major issue is the availability of qualified sensor technologies for use in real-time monitoring and control of integrated physical/chemical/biological (p/c/b) Environmental Control and Life Support Systems (ECLSS). The purpose of this study is to determine the most promising instrumentation technologies for future ECLSS applications. The study approach is as follows: 1. Precursor ECLSS Subsystem Technology Trade Study - A database of existing and advanced Atmosphere Revitalization (AR) and Water Recovery and Management (WRM) ECLSS subsystem technologies was created. A trade study was performed to recommend AR and WRM subsystem technologies for future lunar and Mars mission scenarios. The purpose of this trade study was to begin defining future ECLSS instrumentation requirements as a precursor to determining the instrumentation technologies that will be applicable to future ECLS systems. 2. Instrumentation Survey - An instrumentation database of Chemical, Microbial, Conductivity, Humidity, Flowrate, Pressure, and Temperature sensors was created. Each page of the sensor database report contains information for one type of sensor, including a description of the operating principles, specifications, and the reference(s) from which the information was obtained. This section includes a cursory look at the history of instrumentation on U.S. spacecraft. 3. Results and Recommendations - Instrumentation technologies were recommended for further research and optimization based on a consideration of both of the above sections. A sensor or monitor technology was recommended based on its applicability to future ECLS systems, as defined by the ECLSS Trade Study (1), and on whether its characteristics were considered favorable relative to similar instrumentation technologies (competitors), as determined from the Instrumentation Survey (2). The instrumentation technologies recommended by this study show considerable potential for development and promise significant returns if research efforts are invested.

  4. Future Integrated Systems Concept for Preventing Aircraft Loss-of-Control Accidents

    NASA Technical Reports Server (NTRS)

    Belcastro, Christine M.; Jacobson, Steven r.

    2010-01-01

    Loss of control remains one of the largest contributors to aircraft fatal accidents worldwide. Aircraft loss-of-control accidents are highly complex in that they can result from numerous causal and contributing factors acting alone or (more often) in combination. Hence, there is no single intervention strategy to prevent these accidents. This paper presents future system concepts and research directions for preventing aircraft loss-of-control accidents.

  5. Reward and social valuation deficits following ventromedial prefrontal damage.

    PubMed

    Moretti, Laura; Dragone, Davide; di Pellegrino, Giuseppe

    2009-01-01

    Lesion and imaging studies have implicated the ventromedial prefrontal cortex (vmPFC) in economic decisions and social interactions, yet its exact functions remain unclear. Here, we investigated the hypothesis that the vmPFC represents the subjective value or desirability of future outcomes during social decision-making. Both vmPFC-damaged patients and control participants acted as the responder in a single-round ultimatum game. To test outcome valuation, we contrasted concrete, immediately available gains with abstract, future ones. To test social valuation, we contrasted interactions with a human partner and those involving a computer. We found that, compared to controls, vmPFC patients substantially reduced their acceptance rate of unfair offers from a human partner, but only when financial gains were presented as abstract amounts to be received later. When the gains were visible and readily available, the vmPFC patients' acceptance of unfair offers was normal. Furthermore, unlike controls, vmPFC patients did not distinguish between unfair offers from a human agent and those from a computerized opponent. We conclude that the vmPFC encodes the expected value of abstract, future goals in a common neural currency that takes into account both reward and social signals in order to optimize economic decision-making.

  6. Developmental trends and individual differences in brain systems involved in intertemporal choice during adolescence.

    PubMed

    Banich, Marie T; De La Vega, Alejandro; Andrews-Hanna, Jessica R; Mackiewicz Seghete, Kristen; Du, Yiping; Claus, Eric D

    2013-06-01

    This study used functional magnetic resonance imaging (fMRI) to examine the neural systems activated during an intertemporal choice task in a group of 14- to 19-year-old adolescents, as well as the relationship of such activation patterns to individual differences in the self-reported ability to engage in nonimmediate thinking (i.e., less impulsive and more future-oriented thoughts and action). With increasing age, there was greater differentiation between patterns of brain activity for immediate versus future choices across three distinct brain systems involved in intertemporal choice--those involved in exerting control over behavior, attributing affective value to choices, and imagining future outcomes. Furthermore, a greater propensity toward self-reported nonimmediate thinking was associated with decreased activity in the systems involved in cognitive control, possibly suggesting that individuals with greater self-reported nonimmediate thinking need to rely less on cognitive control regions during conditions of intertemporal choice. These results highlight the role that both developmental age and individual differences play in influencing neural systems involved in intertemporal choice. Implications for understanding the onset of substance abuse disorders during adolescence are discussed. 2013 APA, all rights reserved

  7. Sick Leave within 5 Years of Whiplash Trauma Predicts Recovery: A Prospective Cohort and Register-Based Study

    PubMed Central

    Carstensen, Tina Birgitte Wisbech; Fink, Per; Oernboel, Eva; Kasch, Helge; Jensen, Troels Staehelin; Frostholm, Lisbeth

    2015-01-01

    Background 10–22% of individuals sustaining whiplash trauma develop persistent symptoms resulting in reduced working ability and decreased quality of life, but it is poorly understood why some people do not recover. Various collision and post-collision risk factors have been studied, but little is known about pre-collision risk factors. In particular, the impact of sickness and socioeconomic factors before the collision on recovery is sparsely explored. The aim of this study was to examine if welfare payments received within five years pre-collision predict neck pain and negative change in provisional situation one year post-collision. Methods and Findings 719 individuals with acute whiplash trauma consecutively recruited from emergency departments or primary care after car accidents in Denmark completed questionnaires on socio-demographic and health factors immediately after the collision. After 12 months, a visual analogue scale on neck pain intensity was completed. 3595 matched controls in the general population were sampled, and national public register data on social benefits and any other welfare payments were obtained for participants with acute whiplash trauma and controls from five years pre-collision to 15 months after. Participants with acute whiplash trauma who had received sickness benefit for more than 12 weeks pre-collision had increased odds for negative change in future provisional situation (Odds Ratio (OR) (95% Confidence Interval (CI) = 3.8 (2.1;7.1)) and future neck pain (OR (95%CI) = 3.3 (1.8;6.3)), controlling for other known risk factors. Participants with acute whiplash trauma had weaker attachment to labour market (more weeks of sick leave (χ2(2) = 36.7, p < 0.001) and unemployment (χ2(2) = 12.5, p = 0.002)) pre-collision compared with controls. Experiencing a whiplash trauma raised the odds for future negative change in provisional situation (OR (95%CI) = 3.1 (2.3;4.4)) compared with controls. Conclusions Sick leave before the collision strongly predicted prolonged recovery following whiplash trauma. Participants with acute whiplash trauma had weaker attachment to labour market pre-collision compared with the general population. Neck pain at inclusion predicted future neck pain. Acute whiplash trauma may trigger pre-existing vulnerabilities increasing risk of developing whiplash-associated disorders. PMID:26098860

  8. Emergency Flight Control Using Computer-Controlled Thrust

    NASA Technical Reports Server (NTRS)

    Burcham, Frank W., Jr.; Fullerton, C. Gordon; Stewart, James F.; Gilyard, Glenn B.; Conley, Joseph A.

    1995-01-01

    Propulsion Controlled Aircraft (PCA) systems are digital electronic control systems undergoing development to provide limited maneuvering ability through variations of individual engine thrusts in multiple-engine airplanes. Provide landing capability when control surfaces inoperable. Incorporated on existing and future airplanes that include digital engine controls, digital flight controls, and digital data buses, adding no weight for additional hardware to airplane. Possible to handle total failure of hydraulic system, depending on how surfaces respond to loss of hydraulic pressure, and broken control cables or linkages. Future airplanes incorporate data from Global Positioning System for guidance to any suitable emergency runway in world.

  9. Episodic Future Thinking in Semantic Dementia: A Cognitive and fMRI Study

    PubMed Central

    Viard, Armelle; Piolino, Pascale; Belliard, Serge; de La Sayette, Vincent; Desgranges, Béatrice; Eustache, Francis

    2014-01-01

    Semantic dementia (SD) is characterized by gradual loss of semantic memory. While episodic autobiographical memory seems relatively preserved, behavioral studies suggest that episodic future thinking is impaired. We used fMRI to measure brain activity in four SD patients (JPL, EP, LL, EG) while they envisioned future events and remembered personal past events. Twelve healthy elders served as controls. Episodic quality, emotion, mental imagery and level of consciousness (via remember/know judgements) were checked at debriefing. We analyzed the future compared to the past for each patient. All patients presented lateral temporal atrophy, but varied in terms of frontal and anterior hippocampal atrophy. Patient JPL presented atrophy in bilateral superior medial frontal gyri and left anterior hippocampus and was unable to engage in episodic future thinking, despite hyperactivations in frontal and occipital regions. Patient EP presented no atrophy in the anterior hippocampus, but atrophy in bilateral superior medial frontal gyrus and had difficulties to engage in episodic future thinking. Patient LL presented atrophy in left anterior hippocampus, but hyperactivated its right counterpart for future compared to past thinking, permitting her to project efficiently in the future in an episodic way. Patient EG presented no atrophy in the superior medial frontal gyri or anterior hippocampi and was able to engage in episodic future thinking. Altogether, patients' future projections differed depending on the severity and localization of their atrophy. The functional integrity of bilateral superior medial frontal gyri and anterior hippocampus appear crucial for episodic future thinking: atrophy of both structures strongly impairs future projection, while integrity of these structures or hyperactivation of residual tissue normalizes episodic future projection. PMID:25333997

  10. Energetic Passivity of the Human Ankle Joint.

    PubMed

    Lee, Hyunglae; Hogan, Neville

    2016-12-01

    Understanding the passive or nonpassive behavior of the neuromuscular system is important to design and control robots that physically interact with humans, since it provides quantitative information to secure coupled stability while maximizing performance. This has become more important than ever apace with the increasing demand for robotic technologies in neurorehabilitation. This paper presents a quantitative characterization of passive and nonpassive behavior of the ankle of young healthy subjects, which provides a baseline for future studies in persons with neurological impairments and information for future developments of rehabilitation robots, such as exoskeletal devices and powered prostheses. Measurements using a wearable ankle robot actuating 2 degrees-of-freedom of the ankle combined with curl analysis and passivity analysis enabled characterization of both quasi-static and steady-state dynamic behavior of the ankle, unavailable from single DOF studies. Despite active neuromuscular control over a wide range of muscle activation, in young healthy subjects passive or dissipative ankle behavior predominated.

  11. A genomics study of type 2 diabetes mellitus in U.S. Air Force personnel.

    PubMed

    Lott, Lisa

    2009-07-01

    The military community is at high risk for type 2 diabetes (T2D), especially as it relates to military beneficiaries, although preventive measures can be implemented to reduce disease onset. This study evaluates the prevalence of risk-associated single nucleotide polymorphisms in patients diagnosed with T2D within active duty, retired military, and military-dependent populations on Lackland Air Force Base compared to nondiabetic controls. Results will be used as a basis of comparison to analyze risk-conferring genotypes in the young, healthy active duty population to generate the prevalence of T2D risk-associated factors in our current and future war fighters. Identifying genetic markers of T2D prior to abnormal glucose control and insulin resistance may ultimately adjust future risk through early detection, healthy lifestyle modifications, and disease management programs. Copyright 2009 Diabetes Technology Society.

  12. [The neural mechanisms of cigarette craving and self-control].

    PubMed

    Hayashi, Takuya

    2014-01-01

    A craving for cigarettes or drugs has been believed to be a fundamental psychopathological factor that drives drug-seeking behavior and relapse. Behavioral economics has revealed context-dependent changes in drug craving. Neuroimaging studies have also found craving-related signals that were altered depending on the context of the experiments. A rational decision-making theory modeled such context-dependency and uncovered a pivotal role of the prefrontal cortical circuit in both self-control and craving. Future studies should address how dopaminergic function and stress circuits can modify the function of decision-making circuits, and produce either craving or self-control.

  13. Error detection and response adjustment in youth with mild spastic cerebral palsy: an event-related brain potential study.

    PubMed

    Hakkarainen, Elina; Pirilä, Silja; Kaartinen, Jukka; van der Meere, Jaap J

    2013-06-01

    This study evaluated the brain activation state during error making in youth with mild spastic cerebral palsy and a peer control group while carrying out a stimulus recognition task. The key question was whether patients were detecting their own errors and subsequently improving their performance in a future trial. Findings indicated that error responses of the group with cerebral palsy were associated with weak motor preparation, as indexed by the amplitude of the late contingent negative variation. However, patients were detecting their errors as indexed by the amplitude of the response-locked negativity and thus improved their performance in a future trial. Findings suggest that the consequence of error making on future performance is intact in a sample of youth with mild spastic cerebral palsy. Because the study group is small, the present findings need replication using a larger sample.

  14. Children's Perceptions of Parental Emotional Neglect and Control and Psychopathology

    ERIC Educational Resources Information Center

    Young, Robert; Lennie, Susan; Minnis, Helen

    2011-01-01

    Background: Parental emotional neglect is linked to psychiatric disorder. This study explores the associations between children's perceptions of parental emotional neglect and future psychopathology. Methods: In a school-based longitudinal study of nearly 1,700 children aged 11-15 we explored children's perceptions of parenting, as measured by the…

  15. Brain-Computer Interfaces Using Sensorimotor Rhythms: Current State and Future Perspectives

    PubMed Central

    Yuan, Han; He, Bin

    2014-01-01

    Many studies over the past two decades have shown that people can use brain signals to convey their intent to a computer using brain-computer interfaces (BCIs). BCI systems extract specific features of brain activity and translate them into control signals that drive an output. Recently, a category of BCIs that are built on the rhythmic activity recorded over the sensorimotor cortex, i.e. the sensorimotor rhythm (SMR), has attracted considerable attention among the BCIs that use noninvasive neural recordings, e.g. electroencephalography (EEG), and have demonstrated the capability of multi-dimensional prosthesis control. This article reviews the current state and future perspectives of SMR-based BCI and its clinical applications, in particular focusing on the EEG SMR. The characteristic features of SMR from the human brain are described and their underlying neural sources are discussed. The functional components of SMR-based BCI, together with its current clinical applications are reviewed. Lastly, limitations of SMR-BCIs and future outlooks are also discussed. PMID:24759276

  16. Better futures: a randomized field test of a model for supporting young people in foster care with mental health challenges to participate in higher education.

    PubMed

    Geenen, Sarah; Powers, Laurie E; Phillips, Lee Ann; Nelson, May; McKenna, Jessica; Winges-Yanez, Nichole; Blanchette, Linda; Croskey, Adrienne; Dalton, Lawrence D; Salazar, Amy; Swank, Paul

    2015-04-01

    The purpose of the study was to conduct a preliminary efficacy evaluation of the Better Futures model, which is focused on improving the postsecondary preparation and participation of youth in foster care with mental health challenges. Sixty-seven youth were randomized to either a control group that received typical services or an intervention group, which involved participation in a Summer Institute, individual peer coaching, and mentoring workshops. Findings indicate significant gains for the intervention group on measures of postsecondary participation, postsecondary and transition preparation, hope, self-determination, and mental health empowerment, as compared to the control group. Youth in the intervention group also showed positive trends in the areas of mental health recovery, quality of life, and high school completion. Implications for future research and practice are discussed, while emphasizing the capacities of youth in foster care with mental health conditions to successfully prepare for and participate fully in high education.

  17. Introduction of performance boosters like Ge as channel material for the future of CMOS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Samia, Slimani, E-mail: slimani.samia@gmail.com; Laboratoire de Modélisation et Méthodes de calcul LMMC,20002 Saida; Bouaza, Djellouli, E-mail: djelbou@hotmail.fr

    High mobility materials are being considered to replace Si in the channel to achieve higher drive currents and switching speeds. Ge is one of new attractive channel materials that require CMOS scaling For future technology nodes and future high performance P-MOSFETS, we have studied a nanoscale SOI DG MOSFETs using quantum simulation approach on DG MOSFETs within the variation of Ge channel concentration and in the presence of source and drain doping by replacing Silicon in the channel by Ge using various dielectric constant. The use of high mobility channel (like Ge) to maximize the MOSFET IDsat and simultaneously circumventmore » the poor electrostatic control to suppress short-channel effects and enhance source injection velocity. The leakage current (I{sub off}) can be controlled by different gates oxide thickness more ever the required threshold voltage (V{sub TH}) can be achieved by keeping gate work function and altering the doping channel.« less

  18. Acoustical Engineering Controls and Estimated Return on Investment for DoD Selected High Noise Sources: A Roadmap for Future Noise Control in Acquisition

    DTIC Science & Technology

    2013-04-25

    Room 2A534, 1155 Defense Pentagon, Washington, DC 20301-1155 1. DOCUMENTDESCruPTION a . TYPE b. TITLE Acoustical Engineering Controls and Estimated...Return on Investment for DoD Selected Report Hil!h Noise Sources: A Roadmap for Future Noise Control in Acquisition c. PAGE COUNT d. SUBJECT AREA...175 Acoustical Engineering - Noise Control - Acquisition 2. AUTHOR/SPEAKER a . NAME (Last, First, Middlo Initial) b. RANK c. TITLE Erdman, Joy GS-15

  19. Lessons learned in research: an attempt to study the effects of magnetic therapy.

    PubMed

    Szor, Judy K; Holewinski, Paul

    2002-02-01

    Difficulties related to chronic wound healing research are frequently discussed, but results of less-than-perfect studies commonly are not published. A 16-week, randomized controlled double-blind study attempted to investigate the effect of static magnetic therapy on the healing of diabetic foot ulcers. Of 56 subjects, 37 completed the study. Because of the small sample size, randomization did not control for differences between the two groups, and the data could not be analyzed in any meaningful way. The challenges of performing magnetic therapy research are discussed and considerations for future studies are noted.

  20. Qualitative Future Safety Risk Identification an Update

    NASA Technical Reports Server (NTRS)

    Barr, Lawrence C.

    2017-01-01

    The purpose of this report is to document the results of a high-level qualitative study that was conducted to identify future aviation safety risks and to assess the potential impacts to the National Airspace System (NAS) of NASA Aviation Safety research on these risks. Multiple external sources (for example, the National Transportation Safety Board, the Flight Safety Foundation, the National Research Council, and the Joint Planning and Development Office) were used to develop a compilation of future safety issues risks, also referred to as future tall poles. The primary criterion used to identify the most critical future safety risk issues was that the issue must be cited in several of these sources as a safety area of concern. The tall poles in future safety risk, in no particular order of importance, are as follows: Runway Safety, Loss of Control In Flight, Icing Ice Detection, Loss of Separation, Near Midair Collision Human Fatigue, Increasing Complexity and Reliance on Automation, Vulnerability Discovery, Data Sharing and Dissemination, and Enhanced Survivability in the Event of an Accident.

  1. Implicit depression and hopelessness in remitted depressed individuals.

    PubMed

    Meites, Tiffany M; Deveney, Christen M; Steele, Katherine T; Holmes, Avram J; Pizzagalli, Diego A

    2008-09-01

    Cognitive theories of depression posit that automatically activated cognitive schemas, including negative thoughts about the self and the future, predispose individuals to develop depressive disorders. However, prior research has largely examined these constructs using explicit tests in currently depressed individuals. Using the Implicit Association Test (IAT), the present study examined automatic associations between the self and mood state ("depression IAT") and between the future and mood state ("hopelessness IAT") before and after a negative mood induction in 19 remitted depressed individuals and 23 healthy controls. In the depression IAT, remitted depressed participants exhibited an overall lower tendency to associate themselves with happiness relative to the healthy controls before the mood induction. Control, but not remitted depressed, participants' automatic associations between the self and happiness diminished following the mood induction. Contrary to our hypotheses, no significant findings emerged when considering the hopelessness IAT. Consistent with prior studies, no significant correlations emerged between implicit and explicit biases, suggesting that these measures probe different processes. Results extend prior IAT research by documenting the presence of a reduced tendency to associate the self with happiness in a sample at increased risk for depression.

  2. Muscle contraction during electro-muscular incapacitation: A comparison between square-wave pulses and the TASER(®) X26 Electronic control device.

    PubMed

    Comeaux, James A; Jauchem, James R; Cox, D Duane; Crane, Carrie C; D'Andrea, John A

    2011-01-01

    Electronic control devices (including the Advanced TASER(®) X26 model produced by TASER International) incapacitate individuals by causing muscle contractions. To provide information relevant to development of future potential devices, effects of monophasic square waves with different parameters were compared with those of the X26 electronic control device, using two animal models (frogs and swine). Pulse power, electrical pulse charge, pulse duration, and pulse repetition frequency affected muscle contraction. There was no difference in the charge required, between the square waveform and the X26 waveform, to cause approximately the same muscle-contraction response (in terms of the strength-duration curve). Thus, on the basis of these initial studies, the detailed shape of a waveform may not be important in terms of generating electro-muscular incapacitation. More detailed studies, however, may be required to thoroughly test all potential waveforms to be considered for future use in ECDs. 2010 American Academy of Forensic Sciences. Published 2010. This article is a U.S. Government work and is in the public domain in the U.S.A.

  3. Dose-Response Relationship between Antimicrobial Drugs and Livestock-Associated MRSA in Pig Farming1

    PubMed Central

    Dohmen, Wietske; Bos, Marian E.H.; Verstappen, Koen M.; Houben, Manon; Wagenaar, Jaap A.; Heederik, Dick J.J.

    2015-01-01

    The farming community can be a vehicle for introduction of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) in hospitals. During 2011–2013, an 18-month longitudinal study aimed at reducing the prevalence of LA-MRSA was conducted on 36 pig farms in the Netherlands. Evaluations every 6 months showed a slight decrease in MRSA prevalence in animals and a stable prevalence in farmers and family members. Antimicrobial use, expressed as defined daily dosages per animal per year, decreased 44% during the study period and was associated with declining MRSA prevalence in pigs. MRSA carriage in animals was substantially higher at farms using cephalosporins. Antimicrobial use remained strongly associated with LA-MRSA in humans regardless of the level of animal contact. A risk factor analysis outlined potential future interventions for LA-MRSA control. These results should encourage animal and public health authorities to maintain their efforts in reducing antimicrobial use in livestock and ask for future controlled intervention studies. PMID:25989456

  4. Gynecologic Cancer Prevention and Control in the National Comprehensive Cancer Control Program: Progress, Current Activities, and Future Directions

    PubMed Central

    Lakhani, Naheed; Brown, Phaeydra M.; Larkin, O. Ann; Moore, Angela R.; Hayes, Nikki S.

    2013-01-01

    Abstract Gynecologic cancer confers a large burden among women in the United States. Several evidence-based interventions are available to reduce the incidence, morbidity, and mortality from these cancers. The National Comprehensive Cancer Control Program (NCCCP) is uniquely positioned to implement these interventions in the US population. This review discusses progress and future directions for the NCCCP in preventing and controlling gynecologic cancer. PMID:23865787

  5. Episodic future thinking reduces temporal discounting in healthy adolescents.

    PubMed

    Bromberg, Uli; Lobatcheva, Maria; Peters, Jan

    2017-01-01

    Episodic Future Thinking has proven efficient in reducing impulsive behavior in several adult populations. Whether it also has a beneficial impact on decision making in adolescents is not known. Here the impact of episodic future thinking on discounting behavior was investigated in a sample of healthy adolescents (n = 44, age range 13-16 years). Discounting behavior in trials including episodic future thinking was significantly less impulsive than in control trials (t = 2.74, p = .009, dz = .44). In a subsample we controlled for executive function, alcohol use and developmental measures. Neither executive function nor alcohol use but developmental measures explained variability in the effect of episodic future thinking. These findings reveal that episodic future thinking can improve adolescent decision making while the effect is to some degree modulated by developmental measures.

  6. Using simulation pedagogy to teach clinical education skills: A randomized trial.

    PubMed

    Holdsworth, Clare; Skinner, Elizabeth H; Delany, Clare M

    2016-05-01

    Supervision of students is a key role of senior physiotherapy clinicians in teaching hospitals. The objective of this study was to test the effect of simulated learning environments (SLE) on educators' self-efficacy in student supervision skills. A pilot prospective randomized controlled trial with concealed allocation was conducted. Clinical educators were randomized to intervention (SLE) or control groups. SLE participants completed two 3-hour workshops, which included simulated clinical teaching scenarios, and facilitated debrief. Standard Education (StEd) participants completed two online learning modules. Change in educator clinical supervision self-efficacy (SE) and student perceptions of supervisor skill were calculated. Between-group comparisons of SE change scores were analyzed with independent t-tests to account for potential baseline differences in education experience. Eighteen educators (n = 18) were recruited (SLE [n = 10], StEd [n = 8]). Significant improvements in SE change scores were seen in SLE participants compared to control participants in three domains of self-efficacy: (1) talking to students about supervision and learning styles (p = 0.01); (2) adapting teaching styles for students' individual needs (p = 0.02); and (3) identifying strategies for future practice while supervising students (p = 0.02). This is the first study investigating SLE for teaching skills of clinical education. SLE improved educators' self-efficacy in three domains of clinical education. Sample size limited the interpretation of student ratings of educator supervision skills. Future studies using SLE would benefit from future large multicenter trials evaluating its effect on educators' teaching skills, student learning outcomes, and subsequent effects on patient care and health outcomes.

  7. A dark past, a restrained present, and an apocalyptic future: time perspective, personality, and life satisfaction among anorexia nervosa patients.

    PubMed

    Garcia, Danilo; Granjard, Alexandre; Lundblad, Suzanna; Archer, Trevor

    2017-01-01

    Despite reporting low levels of well-being, anorexia nervosa patients express temperament traits (e.g., extraversion and persistence) necessary for high levels of life satisfaction. Nevertheless, among individuals without eating disorders, a balanced organization of the flow of time, influences life satisfaction beyond temperamental dispositions. A balanced time perspective is defined as: high past positive, low past negative, high present hedonistic, low present fatalistic, and high future. We investigated differences in time perspective dimensions, personality traits, and life satisfaction between anorexia nervosa patients and matched controls. We also investigated if the personality traits and the outlook on time associated to positive levels of life satisfaction among controls also predicted anorexia patients' life satisfaction. Additionally, we investigated if time perspective dimensions predicted life satisfaction beyond personality traits among both patients and controls. A total of 88 anorexia nervosa patients from a clinic in the West of Sweden and 111 gender-age matched controls from a university in the West of Sweden participated in the Study. All participants responded to the Zimbardo Time Perspective Inventory, the Ten Item Personality Inventory, and the Temporal Satisfaction with Life Scale. A t -test showed that patients scored higher in the past negative, the present fatalistic, and the future dimensions, lower in the past positive and the present hedonistic dimensions, higher in conscientiousness, extraversion, and agreeableness, and lower in life satisfaction. Regression analyses showed that life satisfaction was predicted by openness to experience and emotional stability for controls and by emotional stability among patients. When time dimensions were entered in the regression, emotional stability and the past negative and past positive time dimensions predicted life satisfaction among controls, but only the past positive and present hedonistic time dimensions predicted life satisfaction among patients. Anorexia patients were less satisfied with life despite being more conscientious, social, and agreeable than controls. Moreover, compared to controls, patients had an unbalanced time perspective: a dark view of the past (i.e., high past negative), a restrained present (i.e., low present hedonistic) and an apocalyptic view of the future (i.e., high present fatalistic). It is plausible to suggest that, therapeutic interventions should focus on empowering patients to cultivate a sentimental and positive view of the past (i.e., high past positive) and the desire to experience pleasure without concern for future consequences (i.e., high present hedonistic) so that they can make self-directed and flexible choices for their own well-being. Such interventions might have effects on life satisfaction beyond the patients' temperamental disposition.

  8. Source Credibility in Tobacco Control Messaging

    PubMed Central

    Schmidt, Allison M.; Ranney, Leah M.; Pepper, Jessica K.; Goldstein, Adam O.

    2016-01-01

    Objectives Perceived credibility of a message’s source can affect persuasion. This paper reviews how beliefs about the source of tobacco control messages may encourage attitude and behavior change. Methods We conducted a series of searches of the peer-reviewed literature using terms from communication and public health fields. We reviewed research on source credibility, its underlying concepts, and its relation to the persuasiveness of tobacco control messages. Results We recommend an agenda for future research to bridge the gaps between communication literature on source credibility and tobacco control research. Our recommendations are to study the impact of source credibility on persuasion with long-term behavior change outcomes, in different populations and demographic groups, by developing new credibility measures that are topic- and organization-specific, by measuring how credibility operates across media platforms, and by identifying factors that enhance credibility and persuasion. Conclusions This manuscript reviews the state of research on source credibility and identifies gaps that are maximally relevant to tobacco control communication. Knowing first whether a source is perceived as credible, and second, how to enhance perceived credibility, can inform the development of future tobacco control campaigns and regulatory communications. PMID:27525298

  9. Social exclusion, personal control, self-regulation, and stress among substance abuse treatment clients.

    PubMed

    Cole, Jennifer; Logan, T K; Walker, Robert

    2011-01-01

    The purpose of this study was to examine the relationship of social exclusion, personal control, and self-regulation to perceived stress among individuals who participated in publicly funded substance abuse treatment. Participants entered treatment between June 2006 and July 2007 and completed a 12-month follow-up survey by telephone (n=787). The results of the OLS regression analysis indicate that individuals with greater social exclusion factors (e.g. greater economic hardship, lower subjective social standing, greater perceived discrimination), lower perceived control of one's life, and lower self-regulation had higher perceived stress. Furthermore, a significant interaction was found suggesting a stress-buffering effect of personal control between subjective social standing and perceived stress. Interestingly, income status was not significantly related to perceived stress, while economic hardship, which assesses participants' inability to meet basic expenses, was significantly associated with perceived stress. Future research should examine how to integrate the AA/NA teaching about powerlessness and its role in recovery with the importance of increased personal control and self-control in decreasing perceived stress. Implications for future research and substance abuse treatment are discussed. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  10. Ultrahigh-Repetition Pulse Train with Absolute-Phase Control Produced by AN Adiabatic Raman Process

    NASA Astrophysics Data System (ADS)

    Katsuragawa, M.; Suzuki, T.; Shiraga, K.; Arakawa, M.; Onose, T.; Yokoyama, K.; Hong, F. L.; Misawa, K.

    2010-02-01

    We describe the generation of an ultrahigh-repetition-rate train of ultrashort pulses on the basis of an adiabatic Raman process. We also describe recent progress in studies toward the ultimate regime: realization of an ultrahigh-repetition-rate train of monocycle pulses with control of the absolute phase. We comment on the milestones expected in the near future in terms of the study of such novel light sources and the new field of optical science stimulated by their development.

  11. Obsolete Weapons, Unconventional Tactics, and Martyrdom Zeal: How Iran Would Apply Its Asymmetric Naval Warfare Doctrine in a Future Conflict

    DTIC Science & Technology

    2007-04-01

    currently valid OMB control number. 1. REPORT DATE APR 2007 2. REPORT TYPE 3. DATES COVERED 00-00-2007 to 00-00-2007 4. TITLE AND SUBTITLE...studies, defense planning, arms control , peacekeeping, crisis management, regional and coop- erative security. The Marshall Center Occasional Papers...a research project, which was led and funded by the George C. Marshall European Center for Security Studies in Garmisch-Partenkirchen. ∗∗ Jahangir

  12. Virtual Planning at Work: A Tour of NASA Future Flight Central

    NASA Technical Reports Server (NTRS)

    McClenahen, Jim; Dorighi, Nancy S. (Technical Monitor)

    2000-01-01

    FutureFlight Central will permit integration of tomorrow's technologies in a risk-free simulation of any airport, airfield, and tower cab environment. The facility provides an opportunity for airlines to mitigate passenger delays by fine tuning airport hub operations, gate management and ramp movement procedures. It also allows airport managers an opportunity to study effects of various improvements at their airports. Finally, it enables air traffic controllers to provide feedback and to become familiar with new airport operations and technologies before final installation.

  13. Naval Arms Control: A Post-Cold War Reappraisal

    DTIC Science & Technology

    1991-06-01

    94 A . BACKGRO UN D ......................................................................................... 94 B. WHY ...control, but that an appropriate time may come to exist in the future. For reasons why naval arms control may make more sense in the future, but not...34. Current Research on Peace And Violence. Tampere Peace Research Institute, Tampere Finland, Vol XIII, No. 2, 1990, pp. 65-86. For reasons why naval

  14. Basal ganglia atrophy in prodromal Huntington’s disease is detectable over one year using automated segmentation

    PubMed Central

    Majid, DS Adnan; Aron, Adam R; Thompson, Wesley; Sheldon, Sarah; Hamza, Samar; Stoffers, Diederick; Holland, Dominic; Goldstein, Jody; Corey-Bloom, Jody; Dale, Anders M

    2017-01-01

    Background Future clinical trials of neuroprotection in prodromal Huntington’s (known as preHD) require sensitive in vivo imaging biomarkers to track disease progression over the shortest period. Since basal ganglia atrophy is the most prominent structural characteristic of Huntington’s pathology, systematic assessment of longitudinal subcortical atrophy holds great potential for future biomarker development. Methods We studied 36 preHD and 22 age-matched controls using a novel method to quantify regional change from T1-weighted structural images acquired one year apart. We assessed cross-sectional volume differences and longitudinal volumetric change in seven subcortical structures – the accumbens, amygdala, caudate, hippocampus, pallidum, putamen, and thalamus. Results At baseline, accumbens, caudate, pallidum, and putamen volumes were reduced in preHD vs. controls (all p<.01). Longitudinally, atrophy was greater in preHD than controls in the caudate, pallidum, and putamen (all p<.01). Each structure showed a large between-group effect size, especially the pallidum where Cohen’s d was 1.21. Using pallidal atrophy as a biomarker, we estimate that a hypothetical one-year neuroprotection study would require only 35 preHD per arm to detect a 50% slowing in atrophy and only 138 preHD per arm to detect a 25% slowing in atrophy. Conclusions The effect sizes calculated for preHD basal ganglia atrophy over one year are some of the largest reported to date. Consequently, this translates to strikingly small sample size estimates that will greatly facilitate any future neuroprotection study. This underscores the utility of this automatic image segmentation and longitudinal nonlinear registration method for upcoming studies of preHD and other neurodegenerative disorders. PMID:21932302

  15. Recent developments in the remote radio control of insect flight.

    PubMed

    Sato, Hirotaka; Maharbiz, Michel M

    2010-01-01

    The continuing miniaturization of digital circuits and the development of low power radio systems coupled with continuing studies into the neurophysiology and dynamics of insect flight are enabling a new class of implantable interfaces capable of controlling insects in free flight for extended periods. We provide context for these developments, review the state-of-the-art and discuss future directions in this field.

  16. Recent Developments in the Remote Radio Control of Insect Flight

    PubMed Central

    Sato, Hirotaka; Maharbiz, Michel M.

    2010-01-01

    The continuing miniaturization of digital circuits and the development of low power radio systems coupled with continuing studies into the neurophysiology and dynamics of insect flight are enabling a new class of implantable interfaces capable of controlling insects in free flight for extended periods. We provide context for these developments, review the state-of-the-art and discuss future directions in this field. PMID:21629761

  17. National differences in environmental concern and performance are predicted by country age.

    PubMed

    Hershfield, Hal E; Bang, H Min; Weber, Elke U

    2014-01-01

    There are obvious economic predictors of ability and willingness to invest in environmental sustainability. Yet, given that environmental decisions represent trade-offs between present sacrifices and uncertain future benefits, psychological factors may also play a role in country-level environmental behavior. Gott's principle suggests that citizens may use perceptions of their country's age to predict its future continuation, with longer pasts predicting longer futures. Using country- and individual-level analyses, we examined whether longer perceived pasts result in longer perceived futures, which in turn motivate concern for continued environmental quality. Study 1 found that older countries scored higher on an environmental performance index, even when the analysis controlled for country-level differences in gross domestic product and governance. Study 2 showed that when the United States was framed as an old country (vs. a young one), participants were willing to donate more money to an environmental organization. The findings suggest that framing a country as a long-standing entity may effectively prompt proenvironmental behavior.

  18. Prevention and Control of Highway Tunnel Fires

    DOT National Transportation Integrated Search

    1984-05-01

    This study investigates steps that can be taken to reduce the risk, damage, and : fatalities from fires in existing and future highway tunnels and the effect of : unrestricted transit of hazardous materials through them. The history of : highway tunn...

  19. A Tool for Designing MnPASS Access Spacing

    DOT National Transportation Integrated Search

    2018-03-01

    Dynamically priced High Occupancy Toll (HOT) lanes have been recently added to the traffic operations arsenal in an attempt to preserve infrastructure investment in the future by maintaining a control on demand. This study focuses on the operational ...

  20. Hearing: The Future of Sensory Rehabilitation?

    PubMed

    Skoe, Erika

    2017-11-06

    A new randomized, double-blind controlled study has found that playing a video game modeled from sensory foraging behavior can improve the aging brain's ability to hear complex signals hidden in background noise. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Quality Control for Interviews to Obtain Dietary Recalls from Children for Research Studies

    PubMed Central

    SHAFFER, NICOLE M.; THOMPSON, WILLIAM O.; BAGLIO, MICHELLE L.; GUINN, CAROLINE H.; FRYE, FRANCESCA H. A.

    2005-01-01

    Quality control is an important aspect of a study because the quality of data collected provides a foundation for the conclusions drawn from the study. For studies that include interviews, establishing quality control for interviews is critical in ascertaining whether interviews are conducted according to protocol. Despite the importance of quality control for interviews, few studies adequately document the quality control procedures used during data collection. This article reviews quality control for interviews and describes methods and results of quality control for interviews from two of our studies regarding the accuracy of children's dietary recalls; the focus is on quality control regarding interviewer performance during the interview, and examples are provided from studies with children. For our two studies, every interview was audio recorded and transcribed. The audio recording and typed transcript from one interview conducted by each research dietitian either weekly or daily were randomly selected and reviewed by another research dietitian, who completed a standardized quality control for interviews checklist. Major strengths of the methods of quality control for interviews in our two studies include: (a) interviews obtained for data collection were randomly selected for quality control for interviews, and (b) quality control for interviews was assessed on a regular basis throughout data collection. The methods of quality control for interviews described may help researchers design appropriate methods of quality control for interviews for future studies. PMID:15389417

  2. Development of closed loop roll control for magnetic balance systems

    NASA Technical Reports Server (NTRS)

    Covert, E. E.; Haldeman, C. W.; Ramohalli, G.; Way, P.

    1982-01-01

    This research was undertaken with the goal of demonstrating closed loop control of the roll degree of freedom on the NASA prototype magnetic suspension and balance system at the MIT Aerophysics Laboratory, thus, showing feasibility for a roll control system for any large magnetic balance system which might be built in the future. During the research under this grant, study was directed toward the several areas of torque generation, position sensing, model construction and control system design. These effects were then integrated to produce successful closed loop operation of the analogue roll control system. This experience indicated the desirability of microprocessor control for the angular degrees of freedom.

  3. Design and implementation of robust decentralized control laws for the ACES structure at Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Collins, Emmanuel G., Jr.; Phillips, Douglas J.; Hyland, David C.

    1990-01-01

    Many large space system concepts will require active vibration control to satisfy critical performance requirements such as line-of-sight accuracy. In order for these concepts to become operational it is imperative that the benefits of active vibration control be practically demonstrated in ground based experiments. The results of the experiment successfully demonstrate active vibration control for a flexible structure. The testbed is the Active Control Technique Evaluation for Spacecraft (ACES) structure at NASA Marshall Space Flight Center. The ACES structure is dynamically traceable to future space systems and especially allows the study of line-of-sight control issues.

  4. Strategic avionics technology definition studies. Subtask 3-1A3: Electrical Actuation (ELA) Systems Test Facility

    NASA Technical Reports Server (NTRS)

    Rogers, J. P.; Cureton, K. L.; Olsen, J. R.

    1994-01-01

    Future aerospace vehicles will require use of the Electrical Actuator systems for flight control elements. This report presents a proposed ELA Test Facility for dynamic evaluation of high power linear Electrical Actuators with primary emphasis on Thrust Vector Control actuators. Details of the mechanical design, power and control systems, and data acquisition capability of the test facility are presented. A test procedure for evaluating the performance of the ELA Test Facility is also included.

  5. Integrated orbital servicing study follow-on. Volume 3: Engineering test unit and controls

    NASA Technical Reports Server (NTRS)

    1978-01-01

    A one-g servicing demonstration system which can be used to investigate and develop, in a real time hands-on situation, a wide variety of the mechanism and control system aspects of orbital servicing in the form of module exchange is described including the engineering test unit and the servicer servo drive console. A series of recommendations for future work is given concerning the control problem and more efficient module exchanges, mechanical elements, and electronics.

  6. Qualitative Considerations of Nuclear Forces at Lower Numbers and Implications for Future Arms Control Negotiations

    DTIC Science & Technology

    2012-07-01

    focused on increasing the size of the nuclear arsenal. Forsyth, Jr., James Wood, Col B. Chance Saltzman , and Gary Schaub, Jr. “Remembrance of...control. Appendices include reviews of the last two NPRs and a history of strategic arms control. Johnson, Dana J., Christopher J. Bowie, Robert...www.gao.gov/new.items/d11387.pdf Forsyth, James Wood Jr., B. Chance Saltzman , and Gary Schaub, Jr. “Remembrance of Things Past,” Strategic Studies

  7. Prediction of future urban growth using CA-Markov for urban sustainability planning of Banda Aceh, Indonesia

    NASA Astrophysics Data System (ADS)

    Achmad, A.; Irwansyah, M.; Ramli, I.

    2018-03-01

    Banda Aceh experienced rapid growth, both physically, socially, and economically, after the Tsunami that devastated it the end of December in 2004. Hence policy controls are needed to direct the pattern of urban growth to achieve sustainable development for the future. The purpose of this paper is to generate a growth model for Banda Aceh using the CA-Markov process. By knowing the changes in land use between 2005 and 2009 from the results of previous research, simulations for 2013, 2019 and 2029 using the application of Idrisi@Selva. CA-Markov models were prepared to determine the quantity of changes. The simulation results showed that, after the Tsunami, the City of Banda Aceh tended to grow towards the coast. For the control of the LUC, the Banda Aceh City government needs to prepare comprehensive and detailed maps and inventory of LUC for the city to provide basic data and information needed for monitoring and evaluation that can be done effectively and efficiently. An institution for monitoring and evaluation of the urban landscape and the LUC should be formed immediately. This institution could consist of representatives from government, academia, community leaders, the private sector and other experts. The findings from this study can be used to start the monitoring and evaluation of future urban growth. Especially for the coastal areas, the local government should immediately prepare special spatial coastal area plans to control growth in those areas and to ensure that the economic benefits from disaster mitigation and coastal protection are preserved. For the development of the city in the future, it is necessary to achieve a balance between economic development, and social welfare with environmental protection and disaster mitigation. iIt will become a big challenge to achieve sustainable development for the future.

  8. The role of job strain in understanding midlife common mental disorder: a national birth cohort study.

    PubMed

    Harvey, Samuel B; Sellahewa, Dilan A; Wang, Min-Jung; Milligan-Saville, Josie; Bryan, Bridget T; Henderson, Max; Hatch, Stephani L; Mykletun, Arnstein

    2018-06-01

    Long-standing concerns exist about reverse causation and residual confounding in the prospective association between job strain and risk of future common mental disorders. We aimed to address these concerns through analysis of data collected in the UK National Child Development Study, a large British cohort study. Data from the National Child Development Study (n=6870) were analysed by use of multivariate logistic regression to investigate the prospective association between job strain variables at age 45 years and risk of future common mental disorders at age 50 years, controlling for lifetime psychiatric history and a range of other possible confounding variables across the lifecourse. Population attributable fractions were calculated to estimate the public health effect of job strain on midlife mental health. In the final model, adjusted for all measured confounders, high job demands (odds ratio 1·70, 95% CI 1·25-2·32; p=0·0008), low job control (1·89, 1·29-2·77; p=0·0010), and high job strain (2·22, 1·59-3·09; p<0·0001) remained significant independent predictors of future onset of common mental disorder. If causality is assumed, our findings suggest that 14% of new cases of common mental disorder could have been prevented through elimination of high job strain (population attributable fraction 0·14, 0·06-0·20). High job strain appears to independently affect the risk of future common mental disorders in midlife. These findings suggest that modifiable work-related risk factors might be an important target in efforts to reduce the prevalence of common mental disorders. iCare Foundation and Mental Health Branch, NSW Health. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Regulatory focus affects predictions of the future.

    PubMed

    Guo, Tieyuan; Spina, Roy

    2015-02-01

    This research investigated how regulatory focus might influence trend-reversal predictions. We hypothesized that compared with promotion focus, prevention focus hinders sense of control, which in turn predicts more trend-reversal developments. Studies 1 and 3 revealed that participants expected trend-reversal developments to be more likely to occur when they focused on prevention than when they focused on promotion. Study 2 extended the findings by including a control condition, and revealed that participants expected trend-reversal developments to be more likely to occur in the prevention condition than in the promotion and control conditions. Studies 4 and 5 revealed that participants' chronic prevention focus predicted a low sense of control (Study 4), and that promotion focus predicted a high sense of control (Studies 4 and 5). Furthermore, participants with a high sense of control expected trend-reversal developments to be less likely to occur. Thus, the results provided converging evidence for the hypothesis. © 2014 by the Society for Personality and Social Psychology, Inc.

  10. Systematic studies of modified vocalization: the effect of speech rate on speech production measures during metronome-paced speech in persons who stutter.

    PubMed

    Davidow, Jason H

    2014-01-01

    Metronome-paced speech results in the elimination, or substantial reduction, of stuttering moments. The cause of fluency during this fluency-inducing condition is unknown. Several investigations have reported changes in speech pattern characteristics from a control condition to a metronome-paced speech condition, but failure to control speech rate between conditions limits our ability to determine if the changes were necessary for fluency. This study examined the effect of speech rate on several speech production variables during one-syllable-per-beat metronomic speech in order to determine changes that may be important for fluency during this fluency-inducing condition. Thirteen persons who stutter (PWS), aged 18-62 years, completed a series of speaking tasks. Several speech production variables were compared between conditions produced at different metronome beat rates, and between a control condition and a metronome-paced speech condition produced at a rate equal to the control condition. Vowel duration, voice onset time, pressure rise time and phonated intervals were significantly impacted by metronome beat rate. Voice onset time and the percentage of short (30-100 ms) phonated intervals significantly decreased from the control condition to the equivalent rate metronome-paced speech condition. A reduction in the percentage of short phonated intervals may be important for fluency during syllable-based metronome-paced speech for PWS. Future studies should continue examining the necessity of this reduction. In addition, speech rate must be controlled in future fluency-inducing condition studies, including neuroimaging investigations, in order for this research to make a substantial contribution to finding the fluency-inducing mechanism of fluency-inducing conditions. © 2013 Royal College of Speech and Language Therapists.

  11. Systematic Studies of Modified Vocalization: The Effect of Speech Rate on Speech Production Measures During Metronome-Paced Speech in Persons who Stutter

    PubMed Central

    Davidow, Jason H.

    2013-01-01

    Background Metronome-paced speech results in the elimination, or substantial reduction, of stuttering moments. The cause of fluency during this fluency-inducing condition is unknown. Several investigations have reported changes in speech pattern characteristics from a control condition to a metronome-paced speech condition, but failure to control speech rate between conditions limits our ability to determine if the changes were necessary for fluency. Aims This study examined the effect of speech rate on several speech production variables during one-syllable-per-beat metronomic speech, in order to determine changes that may be important for fluency during this fluency-inducing condition. Methods and Procedures Thirteen persons who stutter (PWS), aged 18–62 years, completed a series of speaking tasks. Several speech production variables were compared between conditions produced at different metronome beat rates, and between a control condition and a metronome-paced speech condition produced at a rate equal to the control condition. Outcomes & Results Vowel duration, voice onset time, pressure rise time, and phonated intervals were significantly impacted by metronome beat rate. Voice onset time and the percentage of short (30–100 ms) phonated intervals significantly decreased from the control condition to the equivalent rate metronome-paced speech condition. Conclusions & Implications A reduction in the percentage of short phonated intervals may be important for fluency during syllable-based metronome-paced speech for PWS. Future studies should continue examining the necessity of this reduction. In addition, speech rate must be controlled in future fluency-inducing condition studies, including neuroimaging investigations, in order for this research to make a substantial contribution to finding the fluency-inducing mechanism of fluency-inducing conditions. PMID:24372888

  12. Future trends of global atmospheric antimony emissions from anthropogenic activities until 2050

    NASA Astrophysics Data System (ADS)

    Zhou, Junrui; Tian, Hezhong; Zhu, Chuanyong; Hao, Jiming; Gao, Jiajia; Wang, Yong; Xue, Yifeng; Hua, Shenbin; Wang, Kun

    2015-11-01

    This paper presents the scenario forecast of global atmospheric antimony (Sb) emissions from anthropogenic activities till 2050. The projection scenarios are built based on the comprehensive global antimony emission inventory for the period 1995-2010 which is reported in our previous study. Three scenarios are set up to investigate the future changes of global antimony emissions as well as their source and region contribution characteristics. Trends of activity levels specified as 5 primary source categories are projected by combining the historical trend extrapolation with EIA International energy outlook 2013, while the source-specific dynamic emission factors are determined by applying transformed normal distribution functions. If no major changes in the efficiency of emission control are introduced and keep current air quality legislations (Current Legislation scenario), global antimony emissions will increase by a factor of 2 between 2010 and 2050. The largest increase in Sb emissions is projected from Asia due to large volume of nonferrous metals production and waste incineration. In case of enforcing the pollutant emission standards (Strengthened Control scenario), global antimony emissions in 2050 will stabilize with that of 2010. Moreover, we can anticipate further declines in Sb emissions for all continents with the best emission control performances (Maximum Feasible Technological Reduction scenario). Future antimony emissions from the top 10 largest emitting countries have also been calculated and source category contributions of increasing emissions of these countries present significant diversity. Furthermore, global emission projections in 2050 are distributed within a 1° × 1°latitude/longitude grid. East Asia, Western Europe and North America present remarkable differences in emission intensity under the three scenarios, which implies that source-and-country specific control measures are necessary to be implemented for abating Sb emissions from varied continents and countries in the future.

  13. Self-perception of competencies in adolescents with autism spectrum disorders.

    PubMed

    Furlano, Rosaria; Kelley, Elizabeth A; Hall, Layla; Wilson, Daryl E

    2015-12-01

    Research has demonstrated that, despite difficulties in multiple domains, children with autism spectrum disorders (ASD) show a lack of awareness of these difficulties. A misunderstanding of poor competencies may make it difficult for individuals to adjust their behaviour in accordance with feedback and may lead to greater impairments over time. This study examined self-perceptions of adolescents with ASD (n = 19) and typically developing (TD) mental-age-matched controls (n = 22) using actual performance on objective academic tasks as the basis for ratings. Before completing the tasks, participants were asked how well they thought they would do (pre-task prediction). After completing each task, they were asked how well they thought they did (immediate post-performance) and how well they would do in the future (hypothetical future post-performance). Adolescents with ASD had more positively biased self-perceptions of competence than TD controls. The ASD group tended to overestimate their performance on all ratings of self-perceptions (pre-task prediction, immediate, and hypothetical future post-performance). In contrast, while the TD group was quite accurate at estimating their performance immediately before and after performing the task, they showed some tendency to overestimate their future performance. Future investigation is needed to systematically examine possible mechanisms that may be contributing to these biased self-perceptions. © 2015 International Society for Autism Research, Wiley Periodicals, Inc.

  14. Land Cover and Climate Change May Limit Invasiveness of Rhododendron ponticum in Wales.

    PubMed

    Manzoor, Syed A; Griffiths, Geoffrey; Iizuka, Kotaro; Lukac, Martin

    2018-01-01

    Invasive plant species represent a serious threat to biodiversity precipitating a sustained global effort to eradicate or at least control the spread of this phenomenon. Current distribution ranges of many invasive species are likely to be modified in the future by land cover and climate change. Thus, invasion management can be made more effective by forecasting the potential spread of invasive species. Rhododendron ponticum (L.) is an aggressive invasive species which appears well suited to western areas of the UK. We made use of MAXENT modeling environment to develop a current distribution model and to assess the likely effects of land cover and climatic conditions (LCCs) on the future distribution of this species in the Snowdonia National park in Wales. Six global circulation models (GCMs) and two representative concentration pathways (RCPs), together with a land cover simulation for 2050 were used to investigate species' response to future environmental conditions. Having considered a range of environmental variables as predictors and carried out the AICc-based model selection, we find that under all LCCs considered in this study, the range of R. ponticum in Wales is likely to contract in the future. Land cover and topographic variables were found to be the most important predictors of the distribution of R. ponticum . This information, together with maps indicating future distribution trends will aid the development of mitigation practices to control R. ponticum .

  15. Recent advances in ultrasonic treatment: Challenges and field applications for controlling harmful algal blooms (HABs).

    PubMed

    Park, Jungsu; Church, Jared; Son, Younggyu; Kim, Keug-Tae; Lee, Woo Hyoung

    2017-09-01

    Algal blooms are a naturally occurring phenomenon which can occur in both freshwater and saltwater. However, due to excess nutrient loading in water bodies (e.g. agricultural runoff and industrial activities), harmful algal blooms (HABs) have become an increasing issue globally, and can even cause health effects in humans due to the release of cyanotoxins. Among currently available treatment methods, sonication has received increasing attention for algal control because of its low impact on ecosystems and the environment. The effects of ultrasound on algal cells are well understood and operating parameter such as frequency, intensity, and duration of exposure has been well studied. However, most studies have been limited to laboratory data interpretation due to complicated environmental conditions in the field. Only a few field and pilot tests in small reservoirs were reported and the applicability of ultrasound for HABs prevention and control is still under question. There is a lack of information on the upscaling of ultrasonication devices for HAB control on larger water bodies, considering field influencing factors such as rainfall, light intensity/duration, temperature, water flow, nutrients loading, and turbidity. In this review article, we address the challenges and field considerations of ultrasonic applications for controlling algal blooms. An extensive literature survey, from the fundamentals of ultrasound techniques to recent ultrasound laboratory and field studies, has been thoroughly conducted and summarized to identify future technical expectations for field applications. Case studies investigating spatial distribution of frequency and pressure during sonication are highlighted with future implications. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Epidemiologic studies of electric and magnetic fields and cancer: strategies for extending knowledge.

    PubMed Central

    Savitz, D A

    1993-01-01

    Epidemiologic research concerning electric and magnetic fields in relation to cancer has focused on the potential etiologic roles of residential exposure on childhood cancer and occupational exposure on adult leukemia and brain cancer. Future residential studies must concentrate on exposure assessment that is enhanced by developing models of historical exposure, assessment of the relation between magnetic fields and wire codes, and consideration of alternate exposure indices. Study design issues deserving attention include possible biases in random digit dialing control selection, consideration of the temporal course of exposure and disease, and acquisition of the necessary information to assess the potential value of ecologic studies. Highest priorities are comprehensive evaluation of exposure patterns and sources and examination of the sociology and geography of residential wire codes. Future occupational studies should also concentrate on improved exposure assessment with increased attention to nonutility worker populations and development of historical exposure indicators that are superior to job titles alone. Potential carcinogens in the workplace that could act as confounders need to be more carefully examined. The temporal relation between exposure and disease and possible effect modification by other workplace agents should be incorporated into future studies. The most pressing need is for measurement of exposure patterns in a variety of worker populations and performance of traditional epidemiologic evaluations of cancer occurrence. The principal source of bias toward the null is nondifferential misclassification of exposure with improvements expected to enhance any true etiologic association that is present. Biases away from the null might include biased control selection in residential studies and chemical carcinogens acting as confounders in occupational studies. PMID:8206046

  17. MOD control center automated information systems security evolution

    NASA Technical Reports Server (NTRS)

    Owen, Rich

    1991-01-01

    The role of the technology infusion process in future Control Center Automated Information Systems (AIS) is highlighted. The following subject areas are presented in the form of the viewgraphs: goals, background, threat, MOD's AISS program, TQM, SDLC integration, payback, future challenges, and bottom line.

  18. Distinguishing between Unipolar Depression and Bipolar Depression: Current and Future Clinical and Neuroimaging Perspectives

    PubMed Central

    de Almeida, Jorge Renner Cardoso; Phillips, Mary Louise

    2012-01-01

    Differentiating bipolar disorder (BD) from recurrent unipolar depression (UD) is a major clinical challenge. Main reasons for this include the higher prevalence of depressive relative to hypo/manic symptoms during the course of BD illness and the high prevalence of subthreshold manic symptoms in both BD and UD depression. Identifying objective markers of BD might help improve accuracy in differentiating between BD and UD depression, to ultimately optimize clinical and functional outcome for all depressed individuals. Yet, only eight neuroimaging studies to date directly compared UD and BD depressed individuals. Findings from these studies suggest more widespread abnormalities in white matter connectivity and white matter hyperintensities in BD than UD depression, habenula volume reductions in BD but not UD depression, and differential patterns of functional abnormalities in emotion regulation and attentional control neural circuitry in the two depression types. These findings suggest different pathophysiologic processes, especially in emotion regulation, reward and attentional control neural circuitry in BD versus UD depression. This review thereby serves as a “call to action” to highlight the pressing need for more neuroimaging studies, using larger samples sizes, comparing BD and UD depressed individuals. These future studies should also include dimensional approaches, studies of at risk individuals, and more novel neuroimaging approaches, such as, connectivity analysis and machine learning. Ultimately, these approaches might provide biomarkers to identify individuals at future risk for BD versus UD, and biological targets for more personalized treatment and new treatment developments for BD and UD depression. PMID:22784485

  19. Precipitation and temperature regime over Cyprus as a result of global climate change

    NASA Astrophysics Data System (ADS)

    Giannakopoulos, C.; Hadjinicolaou, P.; Kostopoulou, E.; Varotsos, K. V.; Zerefos, C.

    2010-02-01

    In this study, the impact of global climate change on the temperature and precipitation regime over the island of Cyprus has been investigated. The analysis is based on daily output from a regional climate model (RCM) at a high horizontal resolution (25 km) produced within the framework of the EU-funded ENSEMBLES project. The control run represents the base period 1961-1990 and is used here as reference for comparison with future predictions. Two future periods are studied, 2021-2050 and 2071-2100. For the study area and over the study period, an analysis of the changes associated with the temperature regime and the hydrological cycle, such as mean precipitation and drought duration, is presented. Variations in the mean annual and seasonal rainfall are presented. Changes in the number of hot days/warm nights as well as drought duration are also discussed. These changes should be very important to assess future possible water shortages over the island and to provide a basis for associated impacts on the agricultural sector.

  20. Where There Is a Way, Is There a Will? The Effect of Future Choices on Self-Control

    ERIC Educational Resources Information Center

    Khan, Uzma; Dhar, Ravi

    2007-01-01

    Choices often involve self-control conflicts such that options that are immediately appealing are less desirable in the long run. In the current research, the authors examine how viewing such a choice as one of a series of similar future choices rather than as an isolated decision decreases the preference for items requiring self-control. The…

  1. Aircraft Loss of Control Study

    NASA Technical Reports Server (NTRS)

    Jacobson, Steven R.

    2010-01-01

    Loss of control has become the leading cause of jet fatalities worldwide. Aside from their frequency of occurrence, accidents resulting from loss of aircraft control seize the public s attention by yielding large numbers of fatalities in a single event. In response to the rising threat to aviation safety, NASA's Aviation Safety Program has conducted a study of the loss of control problem. This study gathered four types of information pertaining to loss of control accidents: (1) statistical data; (2) individual accident reports that cite loss of control as a contributing factor; (3) previous meta-analyses of loss of control accidents; and (4) inputs solicited from aircraft manufacturers, air carriers, researchers, and other industry stakeholders. Using these information resources, the study team identified causal factors that were cited in the greatest number of loss of control accidents, and which were emphasized most by industry stakeholders. For each causal factor that was linked to loss of control, the team solicited ideas about what solutions are required and future research efforts that could potentially help avoid their occurrence or mitigate their consequences when they occurred in flight.

  2. Aircraft Loss-of-Control: Analysis and Requirements for Future Safety-Critical Systems and Their Validation

    NASA Technical Reports Server (NTRS)

    Belcastro, Christine M.

    2011-01-01

    Loss of control remains one of the largest contributors to fatal aircraft accidents worldwide. Aircraft loss-of-control accidents are complex, resulting from numerous causal and contributing factors acting alone or more often in combination. Hence, there is no single intervention strategy to prevent these accidents. This paper summarizes recent analysis results in identifying worst-case combinations of loss-of-control accident precursors and their time sequences, a holistic approach to preventing loss-of-control accidents in the future, and key requirements for validating the associated technologies.

  3. NASA Aircraft Controls Research, 1983

    NASA Technical Reports Server (NTRS)

    Beasley, G. P. (Compiler)

    1984-01-01

    The workshop consisted of 24 technical presentations on various aspects of aircraft controls, ranging from the theoretical development of control laws to the evaluation of new controls technology in flight test vehicles. A special report on the status of foreign aircraft technology and a panel session with seven representatives from organizations which use aircraft controls technology were also included. The controls research needs and opportunities for the future as well as the role envisioned for NASA in that research were addressed. Input from the panel and response to the workshop presentations will be used by NASA in developing future programs.

  4. Design of control-group conditions in clinical trials of behavioral interventions.

    PubMed

    Lindquist, Ruth; Wyman, Jean F; Talley, Kristine M C; Findorff, Mary J; Gross, Cynthia R

    2007-01-01

    To review considerations in the design of placebo (attention) control conditions for community-based clinical trials of health behavior change interventions and to provide practical strategies for the design of control conditions. A well-designed control condition is an essential component of a clinical trial to foster the unambiguous interpretation of study findings. Pitfalls in the design of control conditions in clinical trials of behavioral interventions are identified and strategies to address them are offered. Types of control conditions that have been used in fall prevention trials are described, along with their strengths and weaknesses. The control condition used in the recent fall evaluation and prevention program (FEPP) was designed to overcome limitations of previous trial designs; it is provided to illustrate how to apply specific design principles. Pitfalls in the design of behavioral intervention studies may be avoided with the application of sound design principles. The FEPP active control condition can be used as a model in the design of future studies.

  5. Energy futures: Trading opportunities for the 1980's

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Treat, J.E.; Cowie, S.; Davidson, F.E.

    1984-01-01

    This text gives a broad background in both theory and practice of energy futures trading. It details successful contract requirements. It analyzes fundamental and technical pricing and using both to manage risk and achieve trading objectives. Hedging strategy, financial aspects of trading, accounting procedures, internal control systems and tax implications are all expertly covered. The book concludes with the potential impact of futures trading on the structure of world markets. Contents: Energy futures: an overview; Exchanges and their contracts; Fundamental analysis and the theory of hedging; The principles of technical analysis; Putting it all together; Integrated trading strategies; Energy futures;more » Financing and exposure management in the oil industry; Accounting principles, taxation, and internal control; The potential impacts of trading in oil futures on the world oil market; Appendix; Glossary; Index.« less

  6. Design of Distributed Engine Control Systems with Uncertain Delay.

    PubMed

    Liu, Xiaofeng; Li, Yanxi; Sun, Xu

    Future gas turbine engine control systems will be based on distributed architecture, in which, the sensors and actuators will be connected to the controllers via a communication network. The performance of the distributed engine control (DEC) is dependent on the network performance. This study introduces a distributed control system architecture based on a networked cascade control system (NCCS). Typical turboshaft engine-distributed controllers are designed based on the NCCS framework with a H∞ output feedback under network-induced time delays and uncertain disturbances. The sufficient conditions for robust stability are derived via the Lyapunov stability theory and linear matrix inequality approach. Both numerical and hardware-in-loop simulations illustrate the effectiveness of the presented method.

  7. Design of Distributed Engine Control Systems with Uncertain Delay

    PubMed Central

    Li, Yanxi; Sun, Xu

    2016-01-01

    Future gas turbine engine control systems will be based on distributed architecture, in which, the sensors and actuators will be connected to the controllers via a communication network. The performance of the distributed engine control (DEC) is dependent on the network performance. This study introduces a distributed control system architecture based on a networked cascade control system (NCCS). Typical turboshaft engine-distributed controllers are designed based on the NCCS framework with a H∞ output feedback under network-induced time delays and uncertain disturbances. The sufficient conditions for robust stability are derived via the Lyapunov stability theory and linear matrix inequality approach. Both numerical and hardware-in-loop simulations illustrate the effectiveness of the presented method. PMID:27669005

  8. Choosing Money over Drugs: The Neural Underpinnings of Difficult Choice in Chronic Cocaine Users

    PubMed Central

    Wesley, Michael J.; Lohrenz, Terry; Koffarnus, Mikhail N.; McClure, Samuel M.; De La Garza, Richard; Salas, Ramiro; Thompson-Lake, Daisy G. Y.; Newton, Thomas F.; Bickel, Warren K.; Montague, P. Read

    2014-01-01

    Addiction is considered a disorder that drives individuals to choose drugs at the expense of healthier alternatives. However, chronic cocaine users (CCUs) who meet addiction criteria retain the ability to choose money in the presence of the opportunity to choose cocaine. The neural mechanisms that differentiate CCUs from non-cocaine using controls (Controls) while executing these preferred choices remain unknown. Thus, therapeutic strategies aimed at shifting preferences towards healthier alternatives remain somewhat uninformed. This study used BOLD neuroimaging to examine brain activity as fifty CCUs and Controls performed single- and cross-commodity intertemporal choice tasks for money and/or cocaine. Behavioral analyses revealed preferences for each commodity type. Imaging analyses revealed the brain activity that differentiated CCUs from Controls while choosing money over cocaine. We observed that CCUs devalued future commodities more than Controls. Choices for money as opposed to cocaine correlated with greater activity in dorsal striatum of CCUs, compared to Controls. In addition, choices for future money as opposed to immediate cocaine engaged the left dorsolateral prefrontal cortex (DLPFC) of CCUs more than Controls. These data suggest that the ability of CCUs to execute choices away from cocaine relies on activity in the dorsal striatum and left DLPFC. PMID:25197609

  9. Candidate control design metrics for an agile fighter

    NASA Technical Reports Server (NTRS)

    Murphy, Patrick C.; Bailey, Melvin L.; Ostroff, Aaron J.

    1991-01-01

    Success in the fighter combat environment of the future will certainly demand increasing capability from aircraft technology. These advanced capabilities in the form of superagility and supermaneuverability will require special design techniques which translate advanced air combat maneuvering requirements into design criteria. Control design metrics can provide some of these techniques for the control designer. Thus study presents an overview of control design metrics and investigates metrics for advanced fighter agility. The objectives of various metric users, such as airframe designers and pilots, are differentiated from the objectives of the control designer. Using an advanced fighter model, metric values are documented over a portion of the flight envelope through piloted simulation. These metric values provide a baseline against which future control system improvements can be compared and against which a control design methodology can be developed. Agility is measured for axial, pitch, and roll axes. Axial metrics highlight acceleration and deceleration capabilities under different flight loads and include specific excess power measurements to characterize energy meneuverability. Pitch metrics cover both body-axis and wind-axis pitch rates and accelerations. Included in pitch metrics are nose pointing metrics which highlight displacement capability between the nose and the velocity vector. Roll metrics (or torsion metrics) focus on rotational capability about the wind axis.

  10. TWO-WEEK INHALATION EXPOSURE OF RATS TO LIBBY AMPHIBOLE (LA) AND AMOSITE ASBESTOS

    EPA Science Inventory

    The relative potency of LA compared to UICC amosite was assessed in a subacute inhalation study designed to set exposure levels for a future subchronic study. Male F344 rats (n=7/group) were exposed nose-only to air (control), 3 concentrations of LA, or I concentration of amosite...

  11. The oak wilt situation

    Treesearch

    William H. Gillespie

    1971-01-01

    Although oak wilt has been studied for more than 30 years, there are many facets of the disease that are little understood. Continuing Federal-State cooperative studies are geared to predicting the overall effects of the disease on future forest management programs, but much additional research is needed before present control programs can be expanded or discarded in a...

  12. An international nomenclature for forest work study

    Treesearch

    Rolf Bjorheden; Michael A. Thompson

    2000-01-01

    Knowledge gained in the study of forest work is used to improve operational efficiency through better planning and control of future work. Internationally recognized standard methods for recording, evaluating and reporting performance in forest work will greatly enhance the usefulness of this information to managers and planners. A subcommittee of IUFRO Working Party...

  13. An international nomenclature for forest work study

    Treesearch

    Rolf Björheden; Michael A.  Thompson

    2000-01-01

    Knowledge gained in the study of forest work is used to improve operational efficiency through better planning and control of future work. Internationally recognized standard methods for recording, evaluating and reporting performance in forest work will greatly enhance the usefulness of this information to managers and planners. A subcommittee of IUFRO Working Party $...

  14. Algebraic methods in system theory

    NASA Technical Reports Server (NTRS)

    Brockett, R. W.; Willems, J. C.; Willsky, A. S.

    1975-01-01

    Investigations on problems of the type which arise in the control of switched electrical networks are reported. The main results concern the algebraic structure and stochastic aspects of these systems. Future reports will contain more detailed applications of these results to engineering studies.

  15. A panel of ancestry informative markers to estimate and correct potential effects of population stratification in Han Chinese.

    PubMed

    Qin, Pengfei; Li, Zhiqiang; Jin, Wenfei; Lu, Dongsheng; Lou, Haiyi; Shen, Jiawei; Jin, Li; Shi, Yongyong; Xu, Shuhua

    2014-02-01

    Population stratification acts as a confounding factor in genetic association studies and may lead to false-positive or false-negative results. Previous studies have analyzed the genetic substructures in Han Chinese population, the largest ethnic group in the world comprising ∼20% of the global human population. In this study, we examined 5540 Han Chinese individuals with about 1 million single-nucleotide polymorphisms (SNPs) and screened a panel of ancestry informative markers (AIMs) to facilitate the discerning and controlling of population structure in future association studies on Han Chinese. Based on genome-wide data, we first confirmed our previous observation of the north-south differentiation in Han Chinese population. Second, we developed a panel of 150 validated SNP AIMs to determine the northern or southern origin of each Han Chinese individual. We further evaluated the performance of our AIMs panel in association studies in simulation analysis. Our results showed that this AIMs panel had sufficient power to discern and control population stratification in Han Chinese, which could significantly reduce false-positive rates in both genome-wide association studies (GWAS) and candidate gene association studies (CGAS). We suggest this AIMs panel be genotyped and used to control and correct population stratification in the study design or data analysis of future association studies, especially in CGAS which is the most popular approach to validate previous reports on genetic associations of diseases in post-GWAS era.

  16. The Indefinite Extension of the Nuclear Non-Proliferation Treaty: A Hinderence or Help to Future Arms Control

    NASA Astrophysics Data System (ADS)

    Pella, Peter J.

    1996-05-01

    The indefinite and "unconditional" extension of the Nuclear Non-Proliferation Treaty (NPT) was achieved almost one year ago today. This outcome was a major foreign policy goal of the Clinton Administration. Some critics of the NPT's indefinite extension claim that nuclear weapons states parties to the NPT have now legitimized their possession of nuclear weapons for all time and that there is no incentive for future nuclear arms control and disarmament measures. A discussion of how the indefinite extension of the NPT has affected the nuclear arms control landscape and the prospects for future disarmament measures will be discussed.

  17. Left behind or moving forward? Effects of possible selves and strategies to attain them among rural Chinese children.

    PubMed

    Bi, Chongzeng; Oyserman, Daphna

    2015-10-01

    Are possible selves and strategies to attain them universally helpful even among children with few resources? We test this question in rural China. Rural Chinese children are commonly "left behind" (LB) by parents seizing economic opportunities by migrating, hoping the family will "move forward" and their children will attain their predestined better future. Media, teachers, and peers negatively represent LB children as unruly and undisciplined, with negative fates, making LB a negative stereotype that includes the idea of destiny or fate. Indeed, making the idea of LB salient increases children's fatalism (Study 1 n = 144, Study 2 n = 124). However, having strategies to attain possible future selves predicts better in-class behavior, fewer depressive symptoms, and better exam performance even a year later and controlling for prior performance (Study 3 n = 176, Study 4 n = 145). Possible selves have mixed effects, not always predicting better grades and undermining LB children's self-control. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  18. Collisional cascading - The limits of population growth in low earth orbit

    NASA Technical Reports Server (NTRS)

    Kessler, Donald J.

    1991-01-01

    Random collisions between made-made objects in earth orbit will lead to a significant source of orbital debris, but there are a number of uncertainties in these models, and additional analysis and data are required to fully characterize the future environment. However, the nature of these uncertainties are such that while the future environment is uncertain, the fact that collisions will control the future environment is less uncertain. The data that already exist is sufficient to show that cascading collisions will control the future debris environment with no, or very minor increases in the current low-earth-orbit population. Two populations control this process: explosion fragments and expended rocket bodies and payloads. Practices are already changing to limit explosions in low earth orbit; it is necessary to begin limiting the number of expended rocket bodies and payloads in orbit.

  19. Computational Models Used to Assess US Tobacco Control Policies.

    PubMed

    Feirman, Shari P; Glasser, Allison M; Rose, Shyanika; Niaura, Ray; Abrams, David B; Teplitskaya, Lyubov; Villanti, Andrea C

    2017-11-01

    Simulation models can be used to evaluate existing and potential tobacco control interventions, including policies. The purpose of this systematic review was to synthesize evidence from computational models used to project population-level effects of tobacco control interventions. We provide recommendations to strengthen simulation models that evaluate tobacco control interventions. Studies were eligible for review if they employed a computational model to predict the expected effects of a non-clinical US-based tobacco control intervention. We searched five electronic databases on July 1, 2013 with no date restrictions and synthesized studies qualitatively. Six primary non-clinical intervention types were examined across the 40 studies: taxation, youth prevention, smoke-free policies, mass media campaigns, marketing/advertising restrictions, and product regulation. Simulation models demonstrated the independent and combined effects of these interventions on decreasing projected future smoking prevalence. Taxation effects were the most robust, as studies examining other interventions exhibited substantial heterogeneity with regard to the outcomes and specific policies examined across models. Models should project the impact of interventions on overall tobacco use, including nicotine delivery product use, to estimate preventable health and cost-saving outcomes. Model validation, transparency, more sophisticated models, and modeling policy interactions are also needed to inform policymakers to make decisions that will minimize harm and maximize health. In this systematic review, evidence from multiple studies demonstrated the independent effect of taxation on decreasing future smoking prevalence, and models for other tobacco control interventions showed that these strategies are expected to decrease smoking, benefit population health, and are reasonable to implement from a cost perspective. Our recommendations aim to help policymakers and researchers minimize harm and maximize overall population-level health benefits by considering the real-world context in which tobacco control interventions are implemented. © The Author 2017. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. The Impact of Migraine and the Effect of Migraine Treatment on Workplace Productivity in the United States and Suggestions for Future Research

    PubMed Central

    Burton, Wayne N.; Landy, Stephen H.; Downs, Kristen E.; Runken, M. Chris

    2009-01-01

    Evidence suggests that migraine is associated with decreased productivity. This article describes the results of a systematic literature review of peer-reviewed publications that measured the impact of migraine on workplace productivity in the United States and provides recommendations for future research. A MEDLINE search was conducted from January 1, 1990 to July 31, 2008. Articles were included if the results were from a prospective or retrospective study that reported work-specific productivity outcomes in adults with migraine in the United States. Twenty-six studies were included. Nine studies found that diagnosed and/or undiagnosed migraine had a negative impact on worker productivity. Although one migraine prophylactic study found a statistically significant improvement in worker productivity for topiramate-treated patients, another found an insignificant difference in lisinopril-treated patients. Fifteen studies compared the impact of triptan therapy with a control group. The control groups in these studies differed with regard to recall periods, time to follow-up, and types of questionnaires used. Almost all studies found that triptan therapy was associated with a statistically significant improvement in loss in worker productivity vs the control group. Health care professionals can reduce the impact of migraine on worker productivity with appropriate therapy. Researchers should collect presenteeism and absenteeism data, report results in units of time, use a validated instrument, carefully consider recall periods, and report worker productivity separately. In addition, patients with undiagnosed migraine should be included in disease burden studies. When evaluating effects of treatment on productivity, researchers should target well-controlled, double-blind studies and conduct productivity research for new treatments. PMID:19411440

  1. The impact of migraine and the effect of migraine treatment on workplace productivity in the United States and suggestions for future research.

    PubMed

    Burton, Wayne N; Landy, Stephen H; Downs, Kristen E; Runken, M Chris

    2009-05-01

    Evidence suggests that migraine is associated with decreased productivity. This article describes the results of a systematic literature review of peer-reviewed publications that measured the impact of migraine on workplace productivity in the United States and provides recommendations for future research. A MEDLINE search was conducted from January 1, 1990 to July 31, 2008. Articles were included if the results were from a prospective or retrospective study that reported work-specific productivity outcomes in adults with migraine in the United States. Twenty-six studies were included. Nine studies found that diagnosed and/or undiagnosed migraine had a negative impact on worker productivity. Although one migraine prophylactic study found a statistically significant improvement in worker productivity for topiramate-treated patients, another found an insignificant difference in lisinopril-treated patients. Fifteen studies compared the impact of triptan therapy with a control group. The control groups in these studies differed with regard to recall periods, time to follow-up, and types of questionnaires used. Almost all studies found that triptan therapy was associated with a statistically significant improvement in loss in worker productivity vs the control group. Health care professionals can reduce the impact of migraine on worker productivity with appropriate therapy. Researchers should collect presenteeism and absenteeism data, report results in units of time, use a validated instrument, carefully consider recall periods, and report worker productivity separately. In addition, patients with undiagnosed migraine should be included in disease burden studies. When evaluating effects of treatment on productivity, researchers should target well-controlled, double-blind studies and conduct productivity research for new treatments.

  2. Anxiety Disorders are Associated with Reduced Heart Rate Variability: A Meta-Analysis.

    PubMed

    Chalmers, John A; Quintana, Daniel S; Abbott, Maree J-Anne; Kemp, Andrew H

    2014-01-01

    Anxiety disorders increase risk of future cardiovascular disease (CVD) and mortality, even after controlling for confounds including smoking, lifestyle, and socioeconomic status, and irrespective of a history of medical disorders. While impaired vagal function, indicated by reductions in heart rate variability (HRV), may be one mechanism linking anxiety disorders to CVD, prior studies have reported inconsistent findings highlighting the need for meta-analysis. Studies comparing resting-state HRV recordings in patients with an anxiety disorder as a primary diagnosis and healthy controls were considered for meta-analysis. Meta-analyses were based on 36 articles, including 2086 patients with an anxiety disorder and 2294 controls. Overall, anxiety disorders were characterized by lower HRV [high frequency (HF): Hedges' g = -0.29. 95% CI: -0.41 to -0.17, p < 0.001; time domain: Hedges' g = -0.45, 95% CI: -0.57 to -0.33, p < 0.001] than controls. Panic disorder (n = 447), post-traumatic stress disorder (n = 192), generalized anxiety disorder (n = 68), and social anxiety disorder (n = 90), but not obsessive-compulsive disorder (n = 40), displayed reductions in HF HRV relative to controls (all ps < 0.001). Anxiety disorders are associated with reduced HRV, findings associated with a small-to-moderate effect size. Findings have important implications for future physical health and well-being of patients, highlighting a need for comprehensive cardiovascular risk reduction.

  3. Subsonic Aircraft Safety Icing Study

    NASA Technical Reports Server (NTRS)

    Jones, Sharon Monica; Reveley, Mary S.; Evans, Joni K.; Barrientos, Francesca A.

    2008-01-01

    NASA's Integrated Resilient Aircraft Control (IRAC) Project is one of four projects within the agency s Aviation Safety Program (AvSafe) in the Aeronautics Research Mission Directorate (ARMD). The IRAC Project, which was redesigned in the first half of 2007, conducts research to advance the state of the art in aircraft control design tools and techniques. A "Key Decision Point" was established for fiscal year 2007 with the following expected outcomes: document the most currently available statistical/prognostic data associated with icing for subsonic transport, summarize reports by subject matter experts in icing research on current knowledge of icing effects on control parameters and establish future requirements for icing research for subsonic transports including the appropriate alignment. This study contains: (1) statistical analyses of accident and incident data conducted by NASA researchers for this "Key Decision Point", (2) an examination of icing in other recent statistically based studies, (3) a summary of aviation safety priority lists that have been developed by various subject-matter experts, including the significance of aircraft icing research in these lists and (4) suggested future requirements for NASA icing research. The review of several studies by subject-matter experts was summarized into four high-priority icing research areas. Based on the Integrated Resilient Aircraft Control (IRAC) Project goals and objectives, the IRAC project was encouraged to conduct work in all of the high-priority icing research areas that were identified, with the exception of the developing of methods to sense and document actual icing conditions.

  4. Expanding the RpoS/σS-Network by RNA Sequencing and Identification of σS-Controlled Small RNAs in Salmonella

    PubMed Central

    Lévi-Meyrueis, Corinne; Monteil, Véronique; Sismeiro, Odile; Dillies, Marie-Agnès; Monot, Marc; Jagla, Bernd; Coppée, Jean-Yves; Dupuy, Bruno; Norel, Françoise

    2014-01-01

    The RpoS/σS sigma subunit of RNA polymerase (RNAP) controls a global adaptive response that allows many Gram-negative bacteria to survive starvation and various stresses. σS also contributes to biofilm formation and virulence of the food-borne pathogen Salmonella enterica serovar Typhimurium (S. Typhimurium). In this study, we used directional RNA-sequencing and complementary assays to explore the σS-dependent transcriptome of S. Typhimurium during late stationary phase in rich medium. This study confirms the large regulatory scope of σS and provides insights into the physiological functions of σS in Salmonella. Extensive regulation by σS of genes involved in metabolism and membrane composition, and down-regulation of the respiratory chain functions, were important features of the σS effects on gene transcription that might confer fitness advantages to bacterial cells and/or populations under starving conditions. As an example, we show that arginine catabolism confers a competitive fitness advantage in stationary phase. This study also provides a firm basis for future studies to address molecular mechanisms of indirect regulation of gene expression by σS. Importantly, the σS-controlled downstream network includes small RNAs that might endow σS with post-transcriptional regulatory functions. Of these, four (RyhB-1/RyhB-2, SdsR, SraL) were known to be controlled by σS and deletion of the sdsR locus had a competitive fitness cost in stationary phase. The σS-dependent control of seven additional sRNAs was confirmed in Northern experiments. These findings will inspire future studies to investigate molecular mechanisms and the physiological impact of post-transcriptional regulation by σS. PMID:24810289

  5. A money management-based substance use treatment increases valuation of future rewards.

    PubMed

    Black, Anne C; Rosen, Marc I

    2011-01-01

    A positive association between delay discounting and substance use has been documented; substance users tend to discount future rewards more than non-users. However, studies detailing the responsiveness of delay discounting to interventions are lacking, and few have examined how any behavioral intervention affects delay discounting and whether these effects moderate changes in substance abuse. This study assesses the effectiveness of a money management intervention, Advisor-Teller Money Manager (ATM), in reducing delay discounting over time and the relationship of these effects to changes in cocaine use. Ninety psychiatric patients with histories of cocaine and/or alcohol use were randomly assigned to 36-weeks of ATM treatment or to a minimal-attention control condition. Delay discounting and cocaine use were measured throughout the intervention with a 52-week follow up measure of cocaine use. Analyses were conducted of (a) the effect of ATM on slopes of delay discounting and cocaine abstinence and (b) the relationship between change in delay discounting and change in cocaine abstinence. The ATM intervention was associated with significantly less delay discounting and less cocaine use over time relative to controls. Increases in delay discounting were associated with decreased abstinence from cocaine. ATM treatment decreased delay discounting rates and these effects extended to cocaine use. Concrete conceptualizations of future events, as occur in financial planning, with higher perceived probability may account for higher valuation of future rewards in counseled patients. Copyright © 2010 Elsevier Ltd. All rights reserved.

  6. Parental Loss, Trusting Relationship with Current Caregivers and Psychosocial Adjustment among Children Affected by AIDS in China

    PubMed Central

    Zhao, Junfeng; Li, Xiaoming; Barnett, Douglas; Lin, Xiuyun; Fang, Xiaoyi; Zhao, Guoxiang; Naar-King, Sylvie; Stanton, Bonita

    2011-01-01

    Objective to examine the relationship between parental loss, trusting relationship with current caregivers, and psychosocial adjustment among children affected by AIDS in China. Methods Cross-sectional data were collected from 755 AIDS orphans (296 double orphans and 459 single orphans), 466 vulnerable children living with HIV-infected parents, and 404 comparison children in China. The trusting relationship with current caregivers was measured with a 15-item scale (Cronbach alpha=.84) modified from the Trusting Relationship Questionnaire (TRQ) developed by Mustillo and colleagues (2005). The psychosocial measures include rule compliance/acting out, anxiety/withdrawal, peer social skills, school interest, depressive symptoms, loneliness, self-esteem, future expectation, hopefulness about future, and perceived control over the future. Results Group mean comparisons using ANOVA suggested a significant association (p<.0001) between the trusting relationship with current caregivers and all the psychosocial measures except anxiety and depression. These associations remained significant in General Linear Model analysis, controlling for children's gender, age, family SES, orphan status (orphans, vulnerable children, and comparison children), and appropriate interaction terms among factor variables. Discussion The findings in the current study support the global literature on the importance of attachment relationship with caregivers in promoting children's psychosocial development. Future prevention intervention efforts to improve AIDS orphans' psychosocial well-being will need to take into consideration the quality of the child's attachment relationships with current caregivers and help their current caregivers to improve the quality of care for these children. Future study is needed to explore the possible reasons for the lack of association between a trusting relationship and some internalizing symptoms such as anxiety and depression among children affected by HIV/AIDS. PMID:21749241

  7. Improving the quality of randomized controlled trials in Chinese herbal medicine, part II: control group design.

    PubMed

    Bian, Zhao-Xiang; Moher, David; Dagenais, Simon; Li, You-Ping; Liu, Liang; Wu, Tai-Xiang; Miao, Jiang-Xia

    2006-03-01

    To discuss the types of control groups in randomized controlled trials (RCTs) of Chinese herbal medicine (CHM), and to provide suggestions for improving the design of control group in future clinical studies in this therapeutic area. A search of the Cochrane Library was conducted in July 2005 to identify RCTs of CHM, and 66 RCTs with CHM for type 2 diabetes mellitus were obtained as the basis for further analysis. Of 66 RCTs with CHM for type 2 diabetes mellitus, 61 (92.4%) trials had both a treatment group and a control group. Twenty-seven (40.9%) RCTs compared CHM plus conventional drug vs conventional drug, 24 (36.4%) compared CHM vs conventional drug, 5 (7.6%) compared CHM vs placebo, 3 (4.5%) compared CHM plus conventional drug vs conventional drug plus placebo, 3 (4.5%) compared CHM plus conventional drug vs other CHM, 1 (1.5%) compared CHM vs no treatment, 1 (1.5%) compared CHM plus placebo vs conventional drug plus placebo, 1 (1.5%) compared CHM vs CHM plus conventional drug vs conventional drug vs placebo, and 1 (1.5%) compared CHM vs conventional drug vs CHM plus conventional drug. A variety of control groups were used in RCTs of CHM for type 2 diabetes mellitus, including placebo, active, and no treatment control groups. Justification for selecting particular types of control groups were not provided in the trials reviewed in this study. Different control groups may be appropriate according to the study objectives, and several factors should be considered prior to selecting control groups in future RCTs of CHM. (1) Investigators of CHM who design clinical trials should understand the rationale for selecting different types of control groups; (2) Control groups for RCTs should be selected according to study objectives; (3) Active control groups should select interventions for comparisons that have the strongest evidence of efficacy and prescribe them as recommended; (4) Placebo control groups should select a placebo that mimics the physical characteristics of test intervention as closely as possible and is completely inert; (5) No treatment control groups should only be used when withholding treatment is ethical and objectives outcomes will not be subject to bias due to absent blinding; (6) Crossover control groups may be appropriate in chronic and stable conditions.

  8. Near East/South Asia Report, Afghanistan: Islam and Political Modernity

    DTIC Science & Technology

    1985-09-11

    Correspondence pertaining to matters other than procurement may be addressed to Joint Publications Research Service, 1000 North Glebe Road, Arlington...power of the clerics, the educated, meaning those who have studied the texts and control their interpretation? This leads to the paradox that the... control over civil society, the key to their future is their liaison with the corps of ulema, their only means of penetrating civil society other

  9. Nutrition and food technology for a Controlled Ecological Life Support System (CELSS)

    NASA Technical Reports Server (NTRS)

    Glaser, P. E.; Mabel, J. A.

    1981-01-01

    Food technology requirements and a nutritional strategy for a Controlled Ecological Life Support System (CELSS) to provide adequate food in an acceptable form in future space missions are discussed. The establishment of nutritional requirements, dietary goals, and a food service system to deliver acceptable foods in a safe and healthy form and the development of research goals and priorities were the main objectives of the study.

  10. Using mental visual imagery to improve autobiographical memory and episodic future thinking in relapsing-remitting multiple sclerosis patients: A randomised-controlled trial study.

    PubMed

    Ernst, Alexandra; Blanc, Frédéric; De Seze, Jérôme; Manning, Liliann

    2015-01-01

    The co-occurrence of autobiographical memory (AM) and episodic future thinking (EFT) impairment has been documented in relapsing-remitting multiple sclerosis (RR-MS) patients. On these bases, we aimed at probing the efficacy of a mental visual imagery (MVI)-based facilitation programme on AM and EFT functioning in the context of a randomised-controlled trial study in RR-MS patients. Using the Autobiographical Interview (AI), 40 patients presenting with an AM/EFT impairment were randomly assigned in three groups: (i) the experimental (n = 17), who followed the MVI programme, (ii) the verbal control (n = 10), who followed a sham verbal programme, and (iii) the stability groups (n = 13), who underwent the AM/EFT test twice, with no intervention in between. AI's second assessment scores showed a significant improvement of AM and EFT performance only for the experimental group, with a long-term robustness of treatment benefits. The control and stability groups' results ruled out nursing and test learning effects as explanations of AM/EFT improvement. These benefits were corroborated by the patients' comments, which indicated an effective MVI strategy transfer to daily life. Our results suggest that the MVI programme tackles a common cognitive process of scene construction present in AM and EFT.

  11. The date-delay framing effect in temporal discounting depends on substance abuse.

    PubMed

    Klapproth, Florian

    2012-07-01

    In the present study, individuals with substance use disorders (n=30) and non-addicted controls (n=30) were presented with a delay-discounting task with time being described either as dates or as temporal intervals. Three main results were obtained. First, in both groups reward size had a large impact on discounting future rewards, with discount rates becoming larger with smaller reward sizes. Second, participants discounted future rewards less strongly when their time of delivery was presented as a date instead of a temporal distance. Third, whereas discount rates of individuals with substance use disorders varied substantially with regard to the presentation of time in the task, the controls changed their choices depending on time presentation only slightly. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. Computer-Controlled Cylindrical Polishing Process for Development of Grazing Incidence Optics for Hard X-Ray Region

    NASA Technical Reports Server (NTRS)

    Khan, Gufran Sayeed; Gubarev, Mikhail; Speegle, Chet; Ramsey, Brian

    2010-01-01

    The presentation includes grazing incidence X-ray optics, motivation and challenges, mid spatial frequency generation in cylindrical polishing, design considerations for polishing lap, simulation studies and experimental results, future scope, and summary. Topics include current status of replication optics technology, cylindrical polishing process using large size polishing lap, non-conformance of polishin lap to the optics, development of software and polishing machine, deterministic prediction of polishing, polishing experiment under optimum conditions, and polishing experiment based on known error profile. Future plans include determination of non-uniformity in the polishing lap compliance, development of a polishing sequence based on a known error profile of the specimen, software for generating a mandrel polishing sequence, design an development of a flexible polishing lap, and computer controlled localized polishing process.

  13. Safety and efficacy of pharmacologic thromboprophylaxis following blunt head injury: a systematic review.

    PubMed

    Reeves, Fairleigh; Batty, Lachlan; Pitt, Veronica; Chau, Marisa; Pattuwage, Loyal; Gruen, Russell L

    2013-10-01

    Patients with blunt head injury are at high risk of venous thromboembolism. However, pharmacologic thromboprophylaxis (PTP) may cause progression of intracranial hemorrhage, and clinicians must often weigh up the risks and benefits. This review aimed to determine whether adding PTP to mechanical prophylaxis confers net benefit or harm and the optimal timing, dose, and agent for PTP in patients with blunt head injury. We searched MEDLINE, EMBASE, The Cochrane Library Central Register of Controlled Trials (CENTRAL), and www.clinicaltrials.gov on April 24, 2013, to identify controlled studies and ongoing trials that assessed the efficacy or safety of thromboprophylaxis interventions in the early management of head-injured patients. Studies were classified based on types of interventions and comparisons, and the quality of included studies was assessed using Cochrane risk-of-bias tool and the Newcastle-Ottawa Quality Assessment Scale. We intended to undertake a meta-analysis if studies were sufficiently similar. Sixteen studies met the inclusion criteria, including four randomized controlled trials. At least two randomized controlled trials were at high risk of bias owing to inadequate randomization and concealment of allocation, and observational studies were potentially confounded by substantial differences between comparison groups. Heterogeneity of included studies precluded meta-analysis. Results were mixed, with some studies supporting and others refuting addition of PTP to mechanical interventions. Little evidence was available about dose or choice of agent. The safety and efficacy of early PTP in patients without early progression of hemorrhage is unclear. There is currently insufficient evidence to guide thromboprophylaxis in patients with blunt head injury. Standardized definitions and outcome measurements would facilitate comparison of outcomes across future studies. Studies in mixed populations should report head-injured specific subgroup data. Future randomized controlled trials should investigate the efficacy and safety of early pharmacologic prophylaxis in addition to mechanical intervention. Systematic review, level IV.

  14. Effects of Trait Self-Control on Response Conflict About Healthy and Unhealthy Food.

    PubMed

    Gillebaart, Marleen; Schneider, Iris K; De Ridder, Denise T D

    2016-12-01

    Self-control leads to positive life outcomes, but it is poorly understood. While previous research has focused on self-control failure, self-control success remains unexplored. The current studies aim to shed more light on the mechanisms of self-control by focusing on the resolution of response conflict as a key component in self-control success. Trait self-control was measured, and participants reported on the magnitude of response conflict they experienced about healthy and unhealthy foods in Study 1 (N = 146; M age  = 33.03; 59 females, 83 males, 4 unknown). The response conflict process was assessed in Study 2 (N = 118; M age  = 21.45; 68 females, 41 males, 9 unknown). Outcomes showed that self-reported evaluative response conflict about food items was smaller for people high in trait self-control. Study 2 revealed that higher trait self-control predicted faster resolution of self-control conflict, and an earlier peak of the response conflict. Taken together, these results provide insight into what makes people with high trait self-control successful, namely, how they handle response conflict. Implications for self-control theories and future directions are discussed. © 2015 Wiley Periodicals, Inc.

  15. Efficacy and safety of damage control in experimental animal models of injury: protocol for a systematic review and meta-analysis

    PubMed Central

    2014-01-01

    Background Although abbreviated surgery with planned reoperation (damage control surgery) is now widely used to manage major trauma patients, the procedure and its component interventions have not been evaluated in randomized controlled trials (RCTs). While some have suggested the need for such trials, they are unlikely to be conducted because of patient safety concerns. As animal studies may overcome several of the limitations of existing observational damage control studies, the primary objective of this study is to evaluate the efficacy and safety of damage control versus definitive surgery in experimental animal models of injury. Methods/design We will search electronic databases (Medline, Embase, PubMed, Web of Science, Scopus, and the Cochrane Library), conference abstracts, personal files, and bibliographies of included articles. We will include RCTs and prospective cohort studies that utilized an animal model of injury and compared damage control surgery (or specific damage control interventions or adjuncts) to definitive surgery (or specific definitive surgical interventions). Two investigators will independently evaluate the internal and external/construct validity of individual studies. The primary outcome will be all-cause mortality. Secondary outcomes will include blood loss amounts; blood pressures and heart rates; urinary outputs; core body temperatures; arterial lactate, pH, and base deficit/excess values; prothrombin and partial thromboplastin times; international normalized ratios; and thromboelastography (TEG) results/activated clotting times. We will calculate summary relative risks (RRs) of mortality and mean differences (for continuous outcomes) using DerSimonian and Laird random effects models. Heterogeneity will be explored using subgroup meta-analysis and meta-regression. We will assess for publication bias using funnel plots and Begg’s and Egger’s tests. When evidence of publication bias exists, we will use the Duval and Tweedie trim and fill method to estimate the potential influence of this bias on pooled summary estimates. Discussion This study will evaluate the efficacy and safety of damage control in experimental animal models of injury. Study results will be used to guide future clinical evaluations of damage control surgery, determine which animal study outcomes may potentially be generalizable to the clinical setting, and to provide guidelines to strengthen the conduct and relevance of future pre-clinical studies. PMID:25416175

  16. The relationship between early ego strength and adolescent responses to the threat of nuclear war

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Andrekus, N.J.

    Ego resiliency and ego control, measured when subjects were 3 or 4 years old, were related to expectation of war, concern for the future, and activism in response to the threat of nuclear war, measured when subjects were 18 years old. Data from 92 participants in a longitudinal study of ego and cognitive development conducted by Jeanne and Jack Block at the University of California, Berkeley were used to test hypotheses. Assessments with the California Child Q-set, composited across multiple independent observers, provide measures of ego resiliency and ego control. Adolescent interviews regarding the perception of likelihood of nuclear war,more » how this affects their future, and their antinuclear and general political activism were scaled and rated. Early ego resiliency and ego under control were hypothesized to account for the variance in adolescent nuclear responses and activism. The only significant longitudinal relationships were in the female sample, where ego under control was found to be a significant predictor of both general political activism (p<.01) and ideas of the future being affected by the nuclear threat (p<.05). Among males, the relationship between early ego resiliency and adolescent antinuclear activism approached significance (p<.10). Adolescent personality was significantly related to several measures of nuclear response. In girls, adolescent ego under control related to perception of likelihood of nuclear war (p<.05) and antinuclear activism (p<.05), and the interaction of ego resiliency and ego under control predicted general political activism (p<.0005). In boys, adolescent ego resiliency correlated with antinuclear activism (p<.05). These findings were discussed in terms of antecedent parenting styles, and conceptual links were drawn between children's ego resiliency and security of attachment, perspective taking, and moral development.« less

  17. Electrochemical biofilm control: a review.

    PubMed

    Sultana, Sujala T; Babauta, Jerome T; Beyenal, Haluk

    2015-01-01

    One of the methods of controlling biofilms that has widely been discussed in the literature is to apply a potential or electrical current to a metal surface on which the biofilm is growing. Although electrochemical biofilm control has been studied for decades, the literature is often conflicting, as is detailed in this review. The goals of this review are: (1) to present the current status of knowledge regarding electrochemical biofilm control; (2) to establish a basis for a fundamental definition of electrochemical biofilm control and requirements for studying it; (3) to discuss current proposed mechanisms; and (4) to introduce future directions in the field. It is expected that the review will provide researchers with guidelines on comparing datasets across the literature and generating comparable datasets. The authors believe that, with the correct design, electrochemical biofilm control has great potential for industrial use.

  18. Integrated control-structure design

    NASA Technical Reports Server (NTRS)

    Hunziker, K. Scott; Kraft, Raymond H.; Bossi, Joseph A.

    1991-01-01

    A new approach for the design and control of flexible space structures is described. The approach integrates the structure and controller design processes thereby providing extra opportunities for avoiding some of the disastrous effects of control-structures interaction and for discovering new, unexpected avenues of future structural design. A control formulation based on Boyd's implementation of Youla parameterization is employed. Control design parameters are coupled with structural design variables to produce a set of integrated-design variables which are selected through optimization-based methodology. A performance index reflecting spacecraft mission goals and constraints is formulated and optimized with respect to the integrated design variables. Initial studies have been concerned with achieving mission requirements with a lighter, more flexible space structure. Details of the formulation of the integrated-design approach are presented and results are given from a study involving the integrated redesign of a flexible geostationary platform.

  19. NATIONAL STORMWATER CALCULATOR: LOW IMPACT DEVELOPMENT STORMWATER CONTROL COST ESTIMATION PROGRAMMING & FUTURE ENHANCEMENTS

    EPA Science Inventory

    National Stormwater Calculator: Low Impact Development Stormwater Control Cost Estimation Programming & Future EnhancementsJason Berner1; Michael Tryby1; Scott Struck2, Dan Pankani2, Marion Deerhake3, Michelle Simon11. USEPA2. GeoSyntec, Inc.3. RTI, Inc.The National Stormwater Ca...

  20. Insect pathogens as biological control agents: back to the future

    USDA-ARS?s Scientific Manuscript database

    In the past 15 years a number of successes and setbacks have taken place regarding development and use of microbial control agents. In this Forum paper we present current information on development, use and future directions of entomopathogenic virus, bacteria, fungi and nematodes as components of i...

  1. Prevention and Control of Methicillin-Resistant Staphylococcus aureus in Acute Care Settings.

    PubMed

    Lee, Andie S; Huttner, Benedikt; Harbarth, Stephan

    2016-12-01

    Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of health care-associated infections worldwide. Controversies with regard to the effectiveness of various MRSA control strategies have contributed to varying approaches to the control of this pathogen in different settings. However, new evidence from large-scale studies has emerged, particularly with regards to MRSA screening and decolonization strategies, which will inform future control practices. The implementation as well as outcomes of control measures in the real world is not only influenced by scientific evidence but also depends on economic, administrative, governmental, and political influences. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Status, Vision, and Challenges of an Intelligent Distributed Engine Control Architecture

    NASA Technical Reports Server (NTRS)

    Behbahani, Alireza; Culley, Dennis; Garg, Sanjay; Millar, Richard; Smith, Bert; Wood, Jim; Mahoney, Tim; Quinn, Ronald; Carpenter, Sheldon; Mailander, Bill; hide

    2007-01-01

    A Distributed Engine Control Working Group (DECWG) consisting of the Department of Defense (DoD), the National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) and industry has been formed to examine the current and future requirements of propulsion engine systems. The scope of this study will include an assessment of the paradigm shift from centralized engine control architecture to an architecture based on distributed control utilizing open system standards. Included will be a description of the work begun in the 1990's, which continues today, followed by the identification of the remaining technical challenges which present barriers to on-engine distributed control.

  3. Positive psychological interventions for children: a comparison of gratitude and best possible selves approaches.

    PubMed

    Owens, Rhea L; Patterson, Meagan M

    2013-01-01

    Many studies have found benefits of positive psychological interventions, such as gratitude promotion or thinking about best possible selves, for adolescents and adults. Almost no research, however, has been conducted on the efficacy of such interventions for children. The authors' primary goal was to compare the outcomes of gratitude promotion and best possible selves interventions to a control condition, using a sample of elementary school-aged children (N = 62, ages 5-11 years). Children participated in once-weekly intervention sessions in which they were asked to draw a picture of something for which they were grateful that day (gratitude condition), a future version of themselves as happy and engaged (best possible selves condition), or something they had done that day (control condition). Analyses of the content of children's drawings indicated that children of this age were capable of articulating things for which they were grateful and positive future selves. Outcomes for the gratitude condition did not differ from the control condition; however, participants in the best possible selves condition showed greater gains in self-esteem than those in the gratitude or control conditions.

  4. Fundamental constructs in food parenting practices: a content map to guide future research.

    PubMed

    Vaughn, Amber E; Ward, Dianne S; Fisher, Jennifer O; Faith, Myles S; Hughes, Sheryl O; Kremers, Stef P J; Musher-Eizenman, Dara R; O'Connor, Teresia M; Patrick, Heather; Power, Thomas G

    2016-02-01

    Although research shows that "food parenting practices" can impact children's diet and eating habits, current understanding of the impact of specific practices has been limited by inconsistencies in terminology and definitions. This article represents a critical appraisal of food parenting practices, including clear terminology and definitions, by a working group of content experts. The result of this effort was the development of a content map for future research that presents 3 overarching, higher-order food parenting constructs--coercive control, structure, and autonomy support--as well as specific practice subconstructs. Coercive control includes restriction, pressure to eat, threats and bribes, and using food to control negative emotions. Structure includes rules and limits, limited/guided choices, monitoring, meal- and snacktime routines, modeling, food availability and accessibility, food preparation, and unstructured practices. Autonomy support includes nutrition education, child involvement, encouragement, praise, reasoning, and negotiation. Literature on each construct is reviewed, and directions for future research are offered. Clear terminology and definitions should facilitate cross-study comparisons and minimize conflicting findings resulting from previous discrepancies in construct operationalization. © The Author(s) 2016. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  5. Past and future cadmium emissions from municipal solid-waste incinerators in Japan for the assessment of cadmium control policy.

    PubMed

    Ono, Kyoko

    2013-11-15

    Cadmium (Cd) is a harmful pollutant emitted from municipal solid-waste incinerators (MSWIs). Cd stack emissions from MSWIs have been estimated between 1970 and 2030 in Japan. The aims of this study are to quantify emitted Cd by category and to analyze Cd control policies to reduce emissions. Emissions were estimated using a dynamic substance flow analysis (SFA) that took into account representative waste treatment flows and historical changes in emission factors. This work revealed that the emissions peaked in 1973 (11.1t) and were ten times those in 2010 (1.2 t). Emission from MSWIs was two-thirds of that from non-ferrous smelting in 2010. The main Cd emission source was pigment use in the 1970s, but after 2000 it had shifted to nickel-cadmium (Ni-Cd) batteries. Future emissions were estimated for 2030. Compared to the business-as-usual scenario, an intensive collection of used Ni-Cd batteries and a ban on any future use of Ni-Cd batteries will reduce emissions by 0.09 and 0.3 1t, respectively, in 2030. This approach enables us to identify the major Cd emission source from MSWIs, and to prioritize the possible Cd control policies. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. Advanced extravehicular protective systems for shuttle, space station, lunar base and Mars missions.

    NASA Technical Reports Server (NTRS)

    Heimlich, P. F.; Sutton, J. G.; Tepper, E. H.

    1972-01-01

    Advances in extravehicular life support system technology will directly influence future space mission reliability and maintainability considerations. To identify required new technology areas, an appraisal of advanced portable life support system and subsystem concepts was conducted. Emphasis was placed on thermal control and combined CO2 control/O2 supply subsystems for both primary and emergency systems. A description of study methodology, concept evaluation techniques, specification requirements, and selected subsystems and systems are presented. New technology recommendations encompassing thermal control, CO2 control and O2 supply subsystems are also contained herein.

  7. Mechanisms for an effect of acetylcysteine on renal function after exposure to radio-graphic contrast material: study protocol.

    PubMed

    Sandilands, Euan A; Cameron, Sharon; Paterson, Frances; Donaldson, Sam; Briody, Lesley; Crowe, Jane; Donnelly, Julie; Thompson, Adrian; Johnston, Neil R; Mackenzie, Ivor; Uren, Neal; Goddard, Jane; Webb, David J; Megson, Ian L; Bateman, Nicholas; Eddleston, Michael

    2012-02-03

    Contrast-induced nephropathy is a common complication of contrast administration in patients with chronic kidney disease and diabetes. Its pathophysiology is not well understood; similarly the role of intravenous or oral acetylcysteine is unclear. Randomized controlled trials to date have been conducted without detailed knowledge of the effect of acetylcysteine on renal function. We are conducting a detailed mechanistic study of acetylcysteine on normal and impaired kidneys, both with and without contrast. This information would guide the choice of dose, route, and appropriate outcome measure for future clinical trials in patients with chronic kidney disease. We designed a 4-part study. We have set up randomised controlled cross-over studies to assess the effect of intravenous (50 mg/kg/hr for 2 hrs before contrast exposure, then 20 mg/kg/hr for 5 hrs) or oral acetylcysteine (1200 mg twice daily for 2 days, starting the day before contrast exposure) on renal function in normal and diseased kidneys, and normal kidneys exposed to contrast. We have also set up a parallel-group randomized controlled trial to assess the effect of intravenous or oral acetylcysteine on patients with chronic kidney disease stage III undergoing elective coronary angiography. The primary outcome is change in renal blood flow; secondary outcomes include change in glomerular filtration rate, tubular function, urinary proteins, and oxidative balance. Contrast-induced nephropathy represents a significant source of hospital morbidity and mortality. Over the last ten years, acetylcysteine has been administered prior to contrast to reduce the risk of contrast-induced nephropathy. Randomized controlled trials, however, have not reliably demonstrated renoprotection; a recent large randomized controlled trial assessing a dose of oral acetylcysteine selected without mechanistic insight did not reduce the incidence of contrast-induced nephropathy. Our study should reveal the mechanism of effect of acetylcysteine on renal function and identify an appropriate route for future dose response studies and in time randomized controlled trials. Clinical Trials.gov: NCT00558142; EudraCT: 2006-003509-18.

  8. Analysis of regional natural flow for evaluation of flood risk according to RCP climate change scenarios

    NASA Astrophysics Data System (ADS)

    Lee, J. Y.; Chae, B. S.; Wi, S.; KIm, T. W.

    2017-12-01

    Various climate change scenarios expect the rainfall in South Korea to increase by 3-10% in the future. The future increased rainfall has significant effect on the frequency of flood in future as well. This study analyzed the probability of future flood to investigate the stability of existing and new installed hydraulic structures and the possibility of increasing flood damage in mid-sized watersheds in South Korea. To achieve this goal, we first clarified the relationship between flood quantiles acquired from the flood-frequency analysis (FFA) and design rainfall-runoff analysis (DRRA) in gauged watersheds. Then, after synthetically generating the regional natural flow data according to RCP climate change scenarios, we developed mathematical formulas to estimate future flood quantiles based on the regression between DRRA and FFA incorporated with regional natural flows in unguaged watersheds. Finally, we developed a flood risk map to investigate the change of flood risk in terms of the return period for the past, present, and future. The results identified that the future flood quantiles and risks would increase in accordance with the RCP climate change scenarios. Because the regional flood risk was identified to increase in future comparing with the present status, comprehensive flood control will be needed to cope with extreme floods in future.

  9. Affective bias and current, past and future adolescent depression: a familial high risk study.

    PubMed

    Kilford, Emma J; Foulkes, Lucy; Potter, Robert; Collishaw, Stephan; Thapar, Anita; Rice, Frances

    2015-03-15

    Affective bias is a common feature of depressive disorder. However, a lack of longitudinal studies means that the temporal relationship between affective bias and depression is not well understood. One group where studies of affective bias may be particularly warranted is the adolescent offspring of depressed parents, given observations of high rates of depression and a severe and impairing course of disorder in this group. A two wave panel design was used in which adolescent offspring of parents with recurrent depression completed a behavioural task assessing affective bias (The Affective Go/No Go Task) and a psychiatric interview. The affective processing of adolescents with current, prior and future depressive disorder was compared to that of adolescents free from disorder. Adolescents with current depression and those who developed depression at follow-up made more commission errors for sad than happy targets compared to adolescents free from disorder. There was no effect of prior depression on later affective processing. Small cell sizes meant we were unable to separately compare those with new onset and recurrent depressive disorder. Valence-specific errors in behavioural inhibition index future vulnerability to depression in adolescents already at increased risk and may represent a measure of affective control. Currently depressed adolescents show a similar pattern of affective bias or deficits in affective control. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  10. Affective bias and current, past and future adolescent depression: A familial high risk study

    PubMed Central

    Kilford, Emma J.; Foulkes, Lucy; Potter, Robert; Collishaw, Stephan; Thapar, Anita; Rice, Frances

    2015-01-01

    Background Affective bias is a common feature of depressive disorder. However, a lack of longitudinal studies means that the temporal relationship between affective bias and depression is not well understood. One group where studies of affective bias may be particularly warranted is the adolescent offspring of depressed parents, given observations of high rates of depression and a severe and impairing course of disorder in this group. Methods A two wave panel design was used in which adolescent offspring of parents with recurrent depression completed a behavioural task assessing affective bias (The Affective Go/No Go Task) and a psychiatric interview. The affective processing of adolescents with current, prior and future depressive disorder was compared to that of adolescents free from disorder. Results Adolescents with current depression and those who developed depression at follow-up made more commission errors for sad than happy targets compared to adolescents free from disorder. There was no effect of prior depression on later affective processing. Limitations Small cell sizes meant we were unable to separately compare those with new onset and recurrent depressive disorder. Conclusions Valence-specific errors in behavioural inhibition index future vulnerability to depression in adolescents already at increased risk and may represent a measure of affective control. Currently depressed adolescents show a similar pattern of affective bias or deficits in affective control. PMID:25527997

  11. Case Study: Lackland Air Force Base Commissary

    EPA Pesticide Factsheets

    DeCA chose to adopt a NH3/CO2 cascade system for two main reasons: (1) to control future capital and operating costs, and (2) to meet the energy and sustainability goals the U.S. Government has established for all public buildings.

  12. Measurement of scour-depth near bridge piers

    USGS Publications Warehouse

    Skinner, J.V.

    1986-01-01

    Because a free-running craft will be undesirably heavy and large, other methods of obtaining scour data are proposed. A tethered craft fitted with a controllable rudder and some methods of measuring scour at a point are presented for future study and development.

  13. Comparing U.S. Army suicide cases to a control sample: initial data and methodological lessons.

    PubMed

    Alexander, Cynthia L; Reger, Mark A; Smolenski, Derek J; Fullerton, Nicole R

    2014-10-01

    Identification of risk and protective factors for suicide is a priority for the United States military, especially in light of the recent steady increase in military suicide rates. The Department of Defense Suicide Event Report contains comprehensive data on suicides for active duty military personnel, but no analogous control data is available to permit identification of factors that differentially determine suicide risk. This proof-of-concept study was conducted to determine the feasibility of collecting such control data. The study employed a prospective case-control design in which control cases were randomly selected from a large Army installation at a rate of four control participants for every qualifying Army suicide. Although 111 Army suicides were confirmed during the study period, just 27 control soldiers completed the study. Despite the small control sample, preliminary analyses comparing suicide cases to controls identified several factors more frequently reported for suicide cases, including recent failed intimate relationships, outpatient mental health history, mood disorder diagnosis, substance abuse history, and prior self-injury. No deployment-related risk factors were found. These data are consistent with existing literature and form a foundation for larger control studies. Methodological lessons learned regarding study design and recruitment are discussed to inform future studies. Reprint & Copyright © 2014 Association of Military Surgeons of the U.S.

  14. A Mission-Adaptive Variable Camber Flap Control System to Optimize High Lift and Cruise Lift-to-Drag Ratios of Future N+3 Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Urnes, James, Sr.; Nguyen, Nhan; Ippolito, Corey; Totah, Joseph; Trinh, Khanh; Ting, Eric

    2013-01-01

    Boeing and NASA are conducting a joint study program to design a wing flap system that will provide mission-adaptive lift and drag performance for future transport aircraft having light-weight, flexible wings. This Variable Camber Continuous Trailing Edge Flap (VCCTEF) system offers a lighter-weight lift control system having two performance objectives: (1) an efficient high lift capability for take-off and landing, and (2) reduction in cruise drag through control of the twist shape of the flexible wing. This control system during cruise will command varying flap settings along the span of the wing in order to establish an optimum wing twist for the current gross weight and cruise flight condition, and continue to change the wing twist as the aircraft changes gross weight and cruise conditions for each mission segment. Design weight of the flap control system is being minimized through use of light-weight shape memory alloy (SMA) actuation augmented with electric actuators. The VCCTEF program is developing better lift and drag performance of flexible wing transports with the further benefits of lighter-weight actuation and less drag using the variable camber shape of the flap.

  15. RNAseq and Proteomics for Analysing Complex Oomycete Plant Interactions.

    PubMed

    Burra, Dharani D; Vetukuri, Ramesh R; Resjö, Svante; Grenville-Briggs, Laura J; Andreasson, Erik

    2016-01-01

    The oomycetes include some of the most devastating plant pathogens. In this review we discuss the latest results from oomycete and plant studies with emphasis on interaction studies. We focus on the outcomes of RNAseq and proteomics studies and some pitfalls of these approaches. Both pathogenic interactions and biological control are discussed. We underline the usefulness of studies at several levels of complexity from studies of one organism, up to two or more and within agricultural fields (managed settings) up to wild ecosystems. Finally we identify areas of future interest such as detailed interactome studies, dual RNAseq studies, peptide modification studies and population/meta omics with or without biological control agents.

  16. Study on the application of NASA energy management techniques for control of a terrestrial solar water heating system

    NASA Technical Reports Server (NTRS)

    Swanson, T. D.; Ollendorf, S.

    1979-01-01

    This paper addresses the potential for enhanced solar system performance through sophisticated control of the collector loop flow rate. Computer simulations utilizing the TRNSYS solar energy program were performed to study the relative effect on system performance of eight specific control algorithms. Six of these control algorithms are of the proportional type: two are concave exponentials, two are simple linear functions, and two are convex exponentials. These six functions are typical of what might be expected from future, more advanced, controllers. The other two algorithms are of the on/off type and are thus typical of existing control devices. Results of extensive computer simulations utilizing actual weather data indicate that proportional control does not significantly improve system performance. However, it is shown that thermal stratification in the liquid storage tank may significantly improve performance.

  17. Scrape-off-layer characterization and current-control of kink modes in HBT-EP

    NASA Astrophysics Data System (ADS)

    Brooks, John; Stewart, Ian; Levesque, Jeffrey; Mauel, Mike; Navratil, Gerald

    2017-10-01

    Scrape-off layer (SOL) currents and their paths through tokamaks are not well understood, but their control may prove crucial to the success of ITER and future fusion energy devices. We extend Columbia University's High Beta Tokamak-Extended Pulse (HBT-EP) experiment and active GPU feedback system to study the SOL and control MHD kink instabilities by actively controlling these currents. First, the radial plasma profiles and the edge structure of kink instabilities are measured with two triple probes. Second, we use active feedback control of a radially adjustable biased electrode to change the rotation and magnitude of slowly growing kink instabilities. By changing the phase between the probe's voltage and the edge instability with active feedback, we study its ability to influence and control plasma MHD structures. This work is in preparation for a planned 2018 multi-electrode SOL control upgrade. Supported by U.S. DOE Grant DE-FG02-86ER53222.

  18. Epidemiology and control of human schistosomiasis in Tanzania

    PubMed Central

    2012-01-01

    In Tanzania, the first cases of schistosomiasis were reported in the early 19th century. Since then, various studies have reported prevalences of up to 100% in some areas. However, for many years, there have been no sustainable control programmes and systematic data from observational and control studies are very limited in the public domain. To cover that gap, the present article reviews the epidemiology, malacology, morbidity, and the milestones the country has made in efforts to control schistosomiasis and discusses future control approaches. The available evidence indicates that, both urinary and intestinal schistosomiasis are still highly endemic in Tanzania and cause significant morbidity.Mass drug administration using praziquantel, currently used as a key intervention measure, has not been successful in decreasing prevalence of infection. There is therefore an urgent need to revise the current approach for the successful control of the disease. Clearly, these need to be integrated control measures. PMID:23192005

  19. Impact of climate change on irrigation management for olive orchards at southern Spain

    NASA Astrophysics Data System (ADS)

    Lorite, Ignacio; Gabaldón-Leal, Clara; Santos, Cristina; Belaj, Angjelina; de la Rosa, Raul; Leon, Lorenzo; Ruiz-Ramos, Margarita

    2017-04-01

    The irrigation management for olive orchards under future weather conditions requires the development of advanced tools for considering specific physiological and phenological components affected by the foreseen changes in climate and atmospheric [CO2]. In this study a new simulation model named AdaptaOlive has been considered to develop controlled deficit irrigation and full irrigation scheduling for the traditional olive orchards located in Andalusia region (southern Spain) under the projected climate generated by an ensemble of 11 climate models from the ENSEMBLES European project corresponding to the SRES A1B scenario. Irrigation requirements, irrigation water productivity (IWP) and net margin (NM) were evaluated for three periods (baseline, near future and far future) and three irrigation strategies (rainfed, RF, controlled deficit irrigation, CDI, and full irrigation, FI). For irrigation requirements, a very limited average increase for far future compared with baseline period was found (2.6 and 1.3%, for CDI and FI, respectively). Equally, when IWP was analyzed, significant increases were identified for both irrigation strategies (77.4 and 72.2%, for CDI and FI, respectively) due to the high simulated increase in yield. Finally, when net margin was analyzed, the irrigation water cost had a key significance. For low water costs FI provided higher net margin values than for CDI. However, for high water costs (expected in the future due to the foreseen reduction in rainfall and the increase of the competence for the available water resources), net margin is reduced significantly, generating a very elevated number of years with negative net margin. All the described results are affected by a high level of uncertainty as the projections from the ensemble of 11 climate models show large spread. Thus, for a representative location within Andalusia region as Baeza, a reduction of irrigation requirements under full irrigation strategy was found for the ensemble mean (equal to 0.5%). However, when the individual projections from the 11 climate models were considered the variation of irrigation requirements for far future compared with baseline period ranged from increases of 8.5% to reductions of 10.7%. This fact demonstrates the necessity to consider ensembles of climate models for identifying averaged impacts and the range of variability of these impacts, quantifying the uncertainty in the estimates related with water management in the future. The study concludes that the promotion of controlled deficit irrigation strategies is an excellent adaptation strategy. However, this strategy must be supported with the enhance of farmers' training by the implementation of local or regional irrigation advisory services.

  20. Episodic Future Thinking in Generalized Anxiety Disorder

    PubMed Central

    Wu, Jade Q.; Szpunar, Karl K.; Godovich, Sheina A.; Schacter, Daniel L.; Hofmann, Stefan G.

    2015-01-01

    Research on future-oriented cognition in generalized anxiety disorder (GAD) has primarily focused on worry, while less is known about the role of episodic future thinking (EFT), an imagery-based cognitive process. To characterize EFT in this disorder, we used the experimental recombination procedure, in which 21 GAD and 19 healthy participants simulated positive, neutral and negative novel future events either once or repeatedly, and rated their phenomenological experience of EFT. Results showed that healthy controls spontaneously generated more detailed EFT over repeated simulations. Both groups found EFT easier to generate after repeated simulations, except when GAD participants simulated positive events. They also perceived higher plausibility of negative—not positive or neutral—future events than did controls. These results demonstrate a negativity bias in GAD individuals’ episodic future cognition, and suggest their relative deficit in generating vivid EFT. We discuss implications for the theory and treatment of GAD. PMID:26398003

  1. Importance of relationship context in HIV transmission: results from a qualitative case-control study in Rakai, Uganda.

    PubMed

    Higgins, Jenny A; Mathur, Sanyukta; Eckel, Elizabeth; Kelley, Laura; Kelly, Laura; Nakyanjo, Neema; Sekamwa, Richard; Namatovu, Josephine; Ddaaki, William; Nakubulwa, Rosette; Namakula, Sylvia; Nalugoda, Fred; Santelli, John S

    2014-04-01

    We present results from life history interviews with 60 young adults from southern Uganda. Using a novel qualitative case-control design, we compared newly HIV-positive cases with HIV-negative controls matched on age, gender, marital status, and place of residence. Relationship context was the most salient theme differentiating cases from controls. Compared with HIV-negative respondents, recent seroconverters described relationships marked by poorer communication, greater suspicion and mistrust, and larger and more transitory sexual networks. Results highlight the importance of dyadic approaches to HIV and possibly of couple-based interventions. Using HIV-matched pairs allowed additional understanding of the factors influencing transmission. This hybrid methodological approach holds promise for future studies of sexual health.

  2. Importance of Relationship Context in HIV Transmission: Results From a Qualitative Case-Control Study in Rakai, Uganda

    PubMed Central

    Mathur, Sanyukta; Eckel, Elizabeth; Kelly, Laura; Nakyanjo, Neema; Sekamwa, Richard; Namatovu, Josephine; Ddaaki, William; Nakubulwa, Rosette; Namakula, Sylvia; Nalugoda, Fred; Santelli, John S.

    2014-01-01

    We present results from life history interviews with 60 young adults from southern Uganda. Using a novel qualitative case-control design, we compared newly HIV-positive cases with HIV-negative controls matched on age, gender, marital status, and place of residence. Relationship context was the most salient theme differentiating cases from controls. Compared with HIV-negative respondents, recent seroconverters described relationships marked by poorer communication, greater suspicion and mistrust, and larger and more transitory sexual networks. Results highlight the importance of dyadic approaches to HIV and possibly of couple-based interventions. Using HIV-matched pairs allowed additional understanding of the factors influencing transmission. This hybrid methodological approach holds promise for future studies of sexual health. PMID:24524490

  3. Control group design: enhancing rigor in research of mind-body therapies for depression.

    PubMed

    Kinser, Patricia Anne; Robins, Jo Lynne

    2013-01-01

    Although a growing body of research suggests that mind-body therapies may be appropriate to integrate into the treatment of depression, studies consistently lack methodological sophistication particularly in the area of control groups. In order to better understand the relationship between control group selection and methodological rigor, we provide a brief review of the literature on control group design in yoga and tai chi studies for depression, and we discuss challenges we have faced in the design of control groups for our recent clinical trials of these mind-body complementary therapies for women with depression. To address the multiple challenges of research about mind-body therapies, we suggest that researchers should consider 4 key questions: whether the study design matches the research question; whether the control group addresses performance, expectation, and detection bias; whether the control group is ethical, feasible, and attractive; and whether the control group is designed to adequately control for nonspecific intervention effects. Based on these questions, we provide specific recommendations about control group design with the goal of minimizing bias and maximizing validity in future research.

  4. Control Group Design: Enhancing Rigor in Research of Mind-Body Therapies for Depression

    PubMed Central

    Kinser, Patricia Anne; Robins, Jo Lynne

    2013-01-01

    Although a growing body of research suggests that mind-body therapies may be appropriate to integrate into the treatment of depression, studies consistently lack methodological sophistication particularly in the area of control groups. In order to better understand the relationship between control group selection and methodological rigor, we provide a brief review of the literature on control group design in yoga and tai chi studies for depression, and we discuss challenges we have faced in the design of control groups for our recent clinical trials of these mind-body complementary therapies for women with depression. To address the multiple challenges of research about mind-body therapies, we suggest that researchers should consider 4 key questions: whether the study design matches the research question; whether the control group addresses performance, expectation, and detection bias; whether the control group is ethical, feasible, and attractive; and whether the control group is designed to adequately control for nonspecific intervention effects. Based on these questions, we provide specific recommendations about control group design with the goal of minimizing bias and maximizing validity in future research. PMID:23662111

  5. Real-time quality assurance testing using photonic techniques: Application to iodine water system

    NASA Technical Reports Server (NTRS)

    Arendale, W. F.; Hatcher, Richard; Garlington, Yadilett; Harwell, Jack; Everett, Tracey

    1990-01-01

    A feasibility study of the use of inspection systems incorporating photonic sensors and multivariate analyses to provide an instrumentation system that in real-time assures quality and that the system in control has been conducted. A system is in control when the near future of the product quality is predictable. Off-line chemical analyses can be used for a chemical process when slow kinetics allows time to take a sample to the laboratory and the system provides a recovery mechanism that returns the system to statistical control without intervention of the operator. The objective for this study has been the implementation of do-it-right-the-first-time and just-in-time philosophies. The Environment Control and Life Support Systems (ECLSS) water reclamation system that adds iodine for biocidal control is an ideal candidate for the study and implementation of do-it-right-the-first-time technologies.

  6. Alcoholics' and nonalcoholics' attributions of control of future life events.

    PubMed

    Wright, M H; Obitz, F W

    1984-03-01

    Alcoholic and nonalcoholic subjects rated the degree of control that they and others possess over future life events. Alcoholics attributed less personal control over events to themselves than nonalcoholics did. Alcoholics also attributed less control to themselves than to others, whereas nonalcoholics attributed more control to themselves than to others. These differences prevailed despite the similar socioeconomic and demographic characteristics, recent life experiences and beliefs concerning the general controllability of events of both alcoholics and nonalcoholics. The attributions of alcoholics were consistent with others' notions of self-handicapping. The attributions of nonalcoholics were consistent with control motivation. Alcoholics who attributed less control to themselves than to others more frequently failed to complete treatment than did alcoholics who attributed more control to themselves.

  7. Alterations of the default mode network connectivity in obsessive-compulsive personality disorder: A pilot study.

    PubMed

    Coutinho, Joana; Goncalves, Oscar Filipe; Soares, José Miguel; Marques, Paulo; Sampaio, Adriana

    2016-10-30

    Obsessive-compulsive personality (OCPD) disorder is characterized by a pattern of excessive self-control, perfectionism and behavioral and cognitive rigidity. Despite the fact that OCPD is the most common personality disorder in the general population, published studies looking at the brain correlates of this disorder are practically nonexistent. The main goal of this study was to analyze the presence of brain alterations in OCPD when compared to healthy controls, specifically at the level of the Default Mode Network (DMN). The DMN is a well-established resting state network which was found to be associated with psychological processes that may play a key role in OCPD (e.g., self-awareness, episodic future thinking and mental simulation). Ten individuals diagnosed with OCPD and ten healthy controls underwent a clinical assessment interview and a resting-state functional magnetic resonance imaging (fMRI) acquisition. The results show that OCPD patients presented an increased functional connectivity in the precuneus (i.e., a posterior node of the DMN), known to be involved in the retrieval manipulation of past events in order to solve current problems and develop plans for the future. These results suggest that this key node of the DMN may play an important role in the pathophysiology of OCPD. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  8. Future orientation and smoking cessation: secondary analysis of data from a smoking cessation trial.

    PubMed

    Beenstock, Jane; Lindson-Hawley, Nicola; Aveyard, Paul; Adams, Jean

    2014-10-01

    To examine the association between future orientation (how individuals consider and value outcomes in the future) and smoking cessation at 4 weeks and 6 months post quit-date in individuals enrolled in a smoking cessation study. Cohort analysis of randomized controlled trial data. UK primary care. Adults aged ≥18 years smoking ≥15 cigarettes daily, prepared to quit in the next 2 weeks. Future orientation was measured prior to quitting and at 4 weeks post-quitting using the Consideration of Future Consequences Scale. Smoking cessation at 4 weeks and 6 months was confirmed biochemically. Those lost to follow-up were assumed to not be abstinent. Potential confounders adjusted for were: age, gender, educational attainment, nicotine dependence and longest previous period quit. A total of 697 participants provided data at baseline; 422 provided information on future orientation at 4 weeks. There was no evidence of an association between future orientation at baseline and abstinence at 4 weeks [adjusted odds ratio (aOR) = 1.05, 95% confidence intervals (CI) 0.80-1.38] or 6 months (aOR = 0.85, 95% CI = 0.60-1.20). There was no change in future orientation from baseline to 4 weeks and no evidence that the change differed between those who were and were not quit at 4 weeks (adjusted regression coefficient = -0.04, 95% CI = -0.16 to 0.08). In smokers who are prepared to quit in the next 2 weeks, the extent of future orientation is unlikely to be a strong predictor of quitting over 4 weeks or 6 months and any increase in future orientation following quitting is likely to be small. © 2014 Society for the Study of Addiction.

  9. Evaluation of the impacts of climate change on disease vectors through ecological niche modelling.

    PubMed

    Carvalho, B M; Rangel, E F; Vale, M M

    2017-08-01

    Vector-borne diseases are exceptionally sensitive to climate change. Predicting vector occurrence in specific regions is a challenge that disease control programs must meet in order to plan and execute control interventions and climate change adaptation measures. Recently, an increasing number of scientific articles have applied ecological niche modelling (ENM) to study medically important insects and ticks. With a myriad of available methods, it is challenging to interpret their results. Here we review the future projections of disease vectors produced by ENM, and assess their trends and limitations. Tropical regions are currently occupied by many vector species; but future projections indicate poleward expansions of suitable climates for their occurrence and, therefore, entomological surveillance must be continuously done in areas projected to become suitable. The most commonly applied methods were the maximum entropy algorithm, generalized linear models, the genetic algorithm for rule set prediction, and discriminant analysis. Lack of consideration of the full-known current distribution of the target species on models with future projections has led to questionable predictions. We conclude that there is no ideal 'gold standard' method to model vector distributions; researchers are encouraged to test different methods for the same data. Such practice is becoming common in the field of ENM, but still lags behind in studies of disease vectors.

  10. Assessing the combined effects of urbanisation and climate change on the river water quality in an integrated urban wastewater system in the UK.

    PubMed

    Astaraie-Imani, Maryam; Kapelan, Zoran; Fu, Guangtao; Butler, David

    2012-12-15

    Climate change and urbanisation are key factors affecting the future of water quality and quantity in urbanised catchments and are associated with significant uncertainty. The work reported in this paper is an evaluation of the combined and relative impacts of climate change and urbanisation on the receiving water quality in the context of an Integrated Urban Wastewater System (IUWS) in the UK. The impacts of intervening system operational control parameters are also investigated. Impact is determined by a detailed modelling study using both local and global sensitivity analysis methods together with correlation analysis. The results obtained from the case-study analysed clearly demonstrate that climate change combined with increasing urbanisation is likely to lead to worsening river water quality in terms of both frequency and magnitude of breaching threshold dissolved oxygen and ammonium concentrations. The results obtained also reveal the key climate change and urbanisation parameters that have the largest negative impact as well as the most responsive IUWS operational control parameters including major dependencies between all these parameters. This information can be further utilised to adapt future IUWS operation and/or design which, in turn, should make these systems more resilient to future climate and urbanisation changes. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Overgeneral past and future thinking in dysphoria: the role of emotional cues and cueing methodology.

    PubMed

    Anderson, Rachel J; Boland, Jennifer; Garner, Sarah R

    2016-01-01

    Overgeneral memory, where individuals exhibit difficulties in retrieving specific episodes from autobiographical memory, has been consistently linked with emotional disorders. However, the majority of this literature has relied upon a single methodology, in which participants respond to emotional cue words with explicit instructions to retrieve/simulate specific events. Through the use of sentence completion tasks the current studies explored whether overgenerality represents a habitual pattern of thinking that extends to how individuals naturally consider their personal past and future life story. In both studies, when compared with controls, dysphoric individuals evidenced overgeneral thinking style with respect to their personal past. However, overgeneral future thinking was only evident when the sentence stems included emotional words. These findings highlight the importance of investigating the overgenerality phenomenon using a variety of cueing techniques and results are discussed with reference to the previous literature exploring overgenerality and cognitive models of depression.

  12. Advanced spacecraft thermal control techniques

    NASA Technical Reports Server (NTRS)

    Fritz, C. H.

    1977-01-01

    The problems of rejecting large amounts of heat from spacecraft were studied. Shuttle Space Laboratory heat rejection uses 1 kW for pumps and fans for every 5 kW (thermal) heat rejection. This is rather inefficient, and for future programs more efficient methods were examined. Two advanced systems were studied and compared to the present pumped-loop system. The advanced concepts are the air-cooled semipassive system, which features rejection of a large percentage of the load through the outer skin, and the heat pipe system, which incorporates heat pipes for every thermal control function.

  13. Crew appliance study

    NASA Technical Reports Server (NTRS)

    Proctor, B. W.; Reysa, R. P.; Russell, D. J.

    1975-01-01

    Viable crew appliance concepts were identified by means of a thorough literature search. Studies were made of the food management, personal hygiene, housekeeping, and off-duty habitability functions to determine which concepts best satisfy the Space Shuttle Orbiter and Modular Space Station mission requirements. Models of selected appliance concepts not currently included in the generalized environmental-thermal control and life support systems computer program were developed and validated. Development plans of selected concepts were generated for future reference. A shuttle freezer conceptual design was developed and a test support activity was provided for regenerative environmental control life support subsystems.

  14. Interdisciplinary study of atmospheric processes and constituents of the mid-Atlantic coastal region.. [air pollution control studies in Virginia

    NASA Technical Reports Server (NTRS)

    Kindle, E. C.; Bandy, E. C.; Copeland, G.; Blais, R.; Levy, G.; Sonenshine, D.

    1975-01-01

    Past research projects for the year 1974-1975 are listed along with future research programs in the area of air pollution control, remote sensor analysis of smoke plumes, the biosphere component, and field experiments. A detailed budget analysis is presented. Attachments are included on the following topics: mapping forest vegetation with ERTS-1 MSS data and automatic data processing techniques, and use of LARS system for the quantitative determination of smoke plume lateral diffusion coefficients from ERTS images of Virginia.

  15. Attitudes towards smoking and tobacco control among pre-clinical medical students in Malaysia.

    PubMed

    Tee, G H; Hairi, N N; Hairi, F

    2012-08-01

    Physicians should play a leading role in combatting smoking; information on attitudes of future physicians towards tobacco control measures in a middle-income developing country is limited. Of 310 future physicians surveyed in a medical school in Malaysia, 50% disagreed that it was a doctor's duty to advise smokers to stop smoking; 76.8% agreed that physicians should not smoke before advising others not to smoke; and 75% agreed to the ideas of restricting the sale of cigarettes to minors, making all public places smoke-free and banning advertising of tobacco-related merchandise. Future physicians had positive attitudes towards tobacco regulations but had not grasped their responsibilities in tobacco control measures.

  16. Training the Future - Swamp Work Activities

    NASA Image and Video Library

    2017-07-19

    In the Swamp Works laboratory at NASA's Kennedy Space Center in Florida, student interns, from the left, Jeremiah House, Thomas Muller and Austin Langdon are joining agency scientists, contributing in the area of Exploration Research and Technology. House is studying computer/electrical engineering at John Brown University in Siloam Springs, Arkansas. Muller is pursuing a degree in computer engineering and control systems and Florida Tech. Langdon is an electrical engineering major at the University of Kentucky. The agency attracts its future workforce through the NASA Internship, Fellowships and Scholarships, or NIFS, Program.

  17. Preventing infections in nursing homes: A survey of infection control practices in southeast Michigan

    PubMed Central

    Mody, Lona; Langa, Kenneth M.; Saint, Sanjay; Bradley, Suzanne F.

    2012-01-01

    Background Studies on adherence to infection control policies in nursing homes (NHs) are limited. This pilot study explores the use of various infection control practices and the role of infection control practitioners in southeast Michigan NHs. Methods A 43-item self-administered questionnaire and explanatory cover letter were mailed to 105 licensed NHs in southeast Michigan. A second mailing was sent to the nonresponders 4 weeks later. Results Significant variability existed in adoption of various infection control measures with respect to time spent in infection control activities (50% of facilities having a full-time infection control practitioner), definitions used in monitoring infections, and immunization rates (influenza: range, 0%–100%; mean, 73.2%; pneumococcal: range, 0%–100%; mean, 38.5%). Conclusion Although strides have been made in infection control research in NHs, significant variations exist in implementation of infection control methods and guidelines. Future research should focus on identifying barriers to infection control in NHs. PMID:16216667

  18. Using memories to motivate future behaviour: an experimental exercise intervention.

    PubMed

    Biondolillo, Mathew J; Pillemer, David B

    2015-01-01

    This study tested a novel memory-based experimental intervention to increase exercise activity. Undergraduate students completed a two-part online survey ostensibly regarding college activity choices. At Time 1, they completed questionnaires that included assessments of exercise-related attitudes, motivation and self-reported behaviours. Next, they described a memory of a positive or negative experience that would increase their motivation to exercise; students in a control condition did not receive a memory prompt. Finally, they rated their intentions to exercise in the future. Eight days following Time 1, students received a Time 2 survey that included an assessment of their self-reported exercise during the prior week. Students in the positive memory condition reported higher levels of subsequent exercise than those in the control condition; students in the negative memory condition reported intermediate levels of exercise. Activating a positive motivational memory had a significant effect on students' self-reported exercise activity even after controlling for prior attitudes, motivation and exercise activity.

  19. Sleep disorders in adults with epilepsy: past, present, and future directions.

    PubMed

    Grigg-Damberger, Madeleine M; Ralls, Frank

    2014-11-01

    To summarize recent studies on the complex relationships between sleep disorders, sleep, and epilepsy. Insomnia in adults with epilepsy (AWE) warrants consideration of depression, anxiety, and suicidal ideation. Daytime sleepiness in AWE is more often due to undiagnosed sleep disorders. Sleep deprivation is an important provoker of seizures in juvenile myoclonic epilepsy. Abnormalities in frontal lobe executive function with difficulties making advantageous decisions may explain failure of juvenile myoclonic epilepsy patients to adhere to treatment recommendations and regulate their sleep habits. Sleep architecture in AWE is more likely to be abnormal if seizures are poorly controlled or occur during sleep. Obstructive sleep apnea is much more common in AWE who are man, older, heavier, or whose seizures are poorly controlled. Chronobiology and chronopharmacology of epilepsy is an emerging field worthy of future research and clinical applications. Identifying and treating unrecognized sleep disorders and understanding the impact of circadian rhythms on epilepsy can improve quality of life and seizure control in AWE.

  20. EVENT PREDICTION AND AFFECTIVE FORECASTING IN DEPRESSIVE COGNITION: USING EMOTION AS INFORMATION ABOUT THE FUTURE.

    PubMed

    Marroquín, Brett; Nolen-Hoeksema, Susan

    2015-02-01

    Depression is characterized by a bleak view of the future, but the mechanisms through which depressed mood is integrated into basic processes of future-oriented cognition are unclear. We hypothesized that dysphoric individuals' predictions of what will happen in the future ( likelihood estimation ) and how the future will feel ( affective forecasting ) are attributable to individual differences in incorporating present emotion as judgment-relevant information. Dysphoric individuals ( n = 77) made pessimistic likelihood estimates and blunted positive affective forecasts relative to controls ( n = 84). These differences were mediated by dysphoric individuals' tendencies to rely on negative emotion as information more than controls-and on positive emotion less-independent of anhedonia. These findings suggest that (1) blunted positive affective forecasting is a distinctive component of depressive future-oriented cognition, and (2) future-oriented cognitive processes are linked not just to current emotional state, but also to individual variation in using that emotion as information. This role of individual differences elucidates basic mechanisms in future-oriented cognition, and suggests routes for intervention on interrelated cognitive and affective processes in depression.

  1. Consumer preferences for health and nonhealth outcomes of health promotion: results from a discrete choice experiment.

    PubMed

    Alayli-Goebbels, Adrienne F G; Dellaert, Benedict G C; Knox, Stephanie A; Ament, André J H A; Lakerveld, Jeroen; Bot, Sandra D M; Nijpels, G; Severens, J L

    2013-01-01

    Health promotion (HP) interventions have outcomes that go beyond health. Such broader nonhealth outcomes are usually neglected in economic evaluation studies. To allow for their consideration, insights are needed into the types of nonhealth outcomes that HP interventions produce and their relative importance compared with health outcomes. This study explored consumer preferences for health and nonhealth outcomes of HP in the context of lifestyle behavior change. A discrete choice experiment was conducted among participants in a lifestyle intervention (n = 132) and controls (n = 141). Respondents made 16 binary choices between situations that can be experienced after lifestyle behavior change. The situations were described by 10 attributes: future health state value, start point of future health state, life expectancy, clothing size above ideal, days with sufficient relaxation, endurance, experienced control over lifestyle choices, lifestyle improvement of partner and/or children, monetary cost per month, and time cost per week. With the exception of "time cost per week" and "start point of future health state," all attributes significantly determined consumer choices. Thus, both health and nonhealth outcomes affected consumer choice. Marginal rates of substitution between the price attribute and the other attributes revealed that the attributes "endurance," "days with sufficient relaxation," and "future health state value" had the greatest impact on consumer choices. The "life expectancy" attribute had a relatively low impact and for increases of less than 3 years, respondents were not willing to trade. Health outcomes and nonhealth outcomes of lifestyle behavior change were both important to consumers in this study. Decision makers should respond to consumer preferences and consider nonhealth outcomes when deciding about HP interventions. Copyright © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  2. UK case control study of brain tumours in children, teenagers and young adults: a pilot study.

    PubMed

    Feltbower, Richard G; Fleming, Sarah J; Picton, Susan V; Alston, Robert D; Morgan, Diana; Achilles, Janice; McKinney, Patricia A; Birch, Jillian M

    2014-01-08

    Tumours of the central nervous system are the second most common group of childhood cancers in 0-14 year olds (24% of total cancers) and represent a major diagnostic group in 15-24 year olds. The pilot case-control study aimed to establish methodologies for a future comprehensive aetiological investigation among children and young adults. Eligible cases were newly diagnosed with an intracranial tumour of neuroepithelial tissue aged 0-24 years. The pilot recruited patients through Leeds and Manchester Principal Treatment Centres. Controls were drawn from general practice lists. Controls were frequency matched by age and gender. We interviewed 49 cases and 78 controls comprising 85% of the target sample size. Response rates were 52% for cases and 32% for controls. Completion of the questionnaire was successful, with a very small proportion of missing data being reported (5-10%). The age distribution of cases and controls was similar with around three-quarters of interviewed subjects aged 0-14. Half of cases and almost two-thirds of controls reported using a mobile phone with the majority starting between 10-14 years of age. Prevalence of breastfeeding was lower in cases than controls (Odds Ratio 0.4; 95% CI 0.2-1.2), whilst cases were more likely to be delivered by caesarean section (OR 1.6; 95% CI 0.6-4.4). Cases were significantly more likely to have a birthweight > 3.5 kg compared to controls. Cases were also more likely to come from a family with 3 or more siblings than controls (OR 3.0; 95% CI 0.7-13.6). The majority of participants (>80%) were in favour of taking either blood or saliva to aid molecular epidemiological research. Successful methods were established for identifying and recruiting a high proportion of case subjects, exploiting strong links with the clinical teams at the treatment centres. Control procedures proved more difficult to implement. However, working closely with national clinical and professional research networks will enable improved control identification and recruitment, with good prospects for collecting biological samples in the future.

  3. Odor tracking in sharks is reduced under future ocean acidification conditions.

    PubMed

    Dixson, Danielle L; Jennings, Ashley R; Atema, Jelle; Munday, Philip L

    2015-04-01

    Recent studies show that ocean acidification impairs sensory functions and alters the behavior of teleost fishes. If sharks and other elasmobranchs are similarly affected, this could have significant consequences for marine ecosystems globally. Here, we show that projected future CO2 levels impair odor tracking behavior of the smooth dogfish (Mustelus canis). Adult M. canis were held for 5 days in a current-day control (405 ± 26 μatm) and mid (741 ± 22 μatm) or high CO2 (1064 ± 17 μatm) treatments consistent with the projections for the year 2100 on a 'business as usual' scenario. Both control and mid CO2 -treated individuals maintained normal odor tracking behavior, whereas high CO2 -treated sharks significantly avoided the odor cues indicative of food. Control sharks spent >60% of their time in the water stream containing the food stimulus, but this value fell below 15% in high CO2 -treated sharks. In addition, sharks treated under mid and high CO2 conditions reduced attack behavior compared to the control individuals. Our findings show that shark feeding could be affected by changes in seawater chemistry projected for the end of this century. Understanding the effects of ocean acidification on critical behaviors, such as prey tracking in large predators, can help determine the potential impacts of future ocean acidification on ecosystem function. © 2014 John Wiley & Sons Ltd.

  4. Response to a comment on Cullen K "From Squires Quest! II: A serious video game intervention": Methodological issues

    USDA-ARS?s Scientific Manuscript database

    In response to comments about our article, "Meal-specific dietary changes from Squires Quest! II: a serious video game intervention," we concur that studies on video game interventions are important. A future study with a control group receiving no video game intervention and the collection of poten...

  5. Evaluating a New Online Course in the Epidemiology of Infectious Diseases by Studying Student Learning Styles

    ERIC Educational Resources Information Center

    Rogers, James W.; Cox, James R.

    2008-01-01

    At RMIT University, students may now elect to study infectious diseases through a course called Outbreak--The Detection and Control of Infectious Disease. Outbreak was designed to simulate in an online class the effective teamwork required to bring resolution to outbreak crises and enable frameworks for future prevention. The appropriateness of…

  6. Measurement Error Correction Formula for Cluster-Level Group Differences in Cluster Randomized and Observational Studies

    ERIC Educational Resources Information Center

    Cho, Sun-Joo; Preacher, Kristopher J.

    2016-01-01

    Multilevel modeling (MLM) is frequently used to detect cluster-level group differences in cluster randomized trial and observational studies. Group differences on the outcomes (posttest scores) are detected by controlling for the covariate (pretest scores) as a proxy variable for unobserved factors that predict future attributes. The pretest and…

  7. Lidar-Enhanced Wind Turbine Control: Past, Present, and Future: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scholbrock, Andrew; Fleming, Paul; Wright, Alan

    2016-07-01

    This paper will look at the development of lidar-enhanced controls and how they have been used for turbine load reduction with pitch actuation, as well as increased energy production with improved yaw control. Ongoing work will also be discussed to show that combining pitch and torque control using feedforward nonlinear model predictive control can lead to both reduced loads and increased energy production. Future work is also proposed on extending individual wind turbine controls to the wind plant level and determining how lidars can be used for control methods to further lower the cost of wind energy by minimizing wakemore » impacts in a wind farm.« less

  8. Child Effortful Control, Teacher-student Relationships, and Achievement in Academically At-risk Children: Additive and Interactive Effects

    PubMed Central

    Liew, Jeffrey; Chen, Qi; Hughes, Jan N.

    2009-01-01

    The joint contributions of child effortful control (using inhibitory control and task accuracy as behavioral indices) and positive teacher-student relationships at first grade on reading and mathematics achievement at second grade were examined in 761 children who were predominantly from low-income and ethnic minority backgrounds and assessed to be academically at-risk at entry to first grade. Analyses accounted for clustering effects, covariates, baselines of effortful control measures, and prior levels of achievement. Even with such conservative statistical controls, interactive effects were found for task accuracy and positive teacher-student relationships on future achievement. Results suggest that task accuracy served as a protective factor so that children with high task accuracy performed well academically despite not having positive teacher-student relationships. Further, positive teacher-student relationships served as a compensatory factor so that children with low task accuracy performed just as well as those with high task accuracy if they were paired with a positive and supportive teacher. Importantly, results indicate that the influence of positive teacher-student relationships on future achievement was most pronounced for students with low effortful control on tasks that require fine motor skills, accuracy, and attention-related skills. Study results have implications for narrowing achievement disparities for academically at-risk children. PMID:20161421

  9. Child Effortful Control, Teacher-student Relationships, and Achievement in Academically At-risk Children: Additive and Interactive Effects.

    PubMed

    Liew, Jeffrey; Chen, Qi; Hughes, Jan N

    2010-01-01

    The joint contributions of child effortful control (using inhibitory control and task accuracy as behavioral indices) and positive teacher-student relationships at first grade on reading and mathematics achievement at second grade were examined in 761 children who were predominantly from low-income and ethnic minority backgrounds and assessed to be academically at-risk at entry to first grade. Analyses accounted for clustering effects, covariates, baselines of effortful control measures, and prior levels of achievement. Even with such conservative statistical controls, interactive effects were found for task accuracy and positive teacher-student relationships on future achievement. Results suggest that task accuracy served as a protective factor so that children with high task accuracy performed well academically despite not having positive teacher-student relationships. Further, positive teacher-student relationships served as a compensatory factor so that children with low task accuracy performed just as well as those with high task accuracy if they were paired with a positive and supportive teacher. Importantly, results indicate that the influence of positive teacher-student relationships on future achievement was most pronounced for students with low effortful control on tasks that require fine motor skills, accuracy, and attention-related skills. Study results have implications for narrowing achievement disparities for academically at-risk children.

  10. Seeing light at the end of the tunnel: Positive prospective mental imagery and optimism in depression.

    PubMed

    Ji, Julie L; Holmes, Emily A; Blackwell, Simon E

    2017-01-01

    Optimism is associated with positive outcomes across many health domains, from cardiovascular disease to depression. However, we know little about cognitive processes underlying optimism in psychopathology. The present study tested whether the ability to vividly imagine positive events in one's future was associated with dispositional optimism in a sample of depressed adults. Cross-sectional and longitudinal analyses were conducted, using baseline (all participants, N=150) and follow-up data (participants in the control condition only, N=63) from a clinical trial (Blackwell et al., 2015). Vividness of positive prospective imagery, assessed on a laboratory-administered task at baseline, was significantly associated with both current optimism levels at baseline and future (seven months later) optimism levels, including when controlling for potential confounds. Even when depressed, those individuals able to envision a brighter future were more optimistic, and regained optimism more quickly over time, than those less able to do so at baseline. Strategies to increase the vividness of positive prospective imagery may aid development of mental health interventions to boost optimism. Copyright © 2016 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  11. Delay of Gratification, Delay Discounting and their Associations with Age, Episodic Future Thinking, and Future Time Perspective.

    PubMed

    Göllner, Lars M; Ballhausen, Nicola; Kliegel, Matthias; Forstmeier, Simon

    2017-01-01

    The delay of gratification (DoG) in children is widely investigated with an experimental procedure originally called the "marshmallow test," whereas the studies on self-regulation (SR) in adolescents and adults usually use self-report questionnaires. Delay discounting (DD) measures simplify the DoG procedure and focus on monetary rewards. The aim of this study was to investigate age differences in DoG and DD from childhood to old age using a test that is suitable for both children and adults. Furthermore, investigations were conducted on the association between DoG/DD and two future orientation constructs [future time perspective (FTP) and episodic future thinking (EFT)] as well as age differences in these constructs. Participants from five age groups (9-14, 18-25, 35-55, 65-80, 80+) participated in the study ( N = 96). While we found no age difference for DoG, DD was the lowest [i.e., self-control (SC) was the highest] in young/middle adults; however, it was the highest (i.e., SC was the lowest) in children and old/oldest adults. Furthermore, we found significant age differences for DD and FTP. As predicted, there were strong correlations between DoG and FTP and between DD and FTP, but not between DoG/DD and EFT. These results indicate that age differences in SR vary across the measures used. Individuals who generally think and act in a future-oriented manner have a stronger ability to delay gratification.

  12. Interpersonal and cultural issues involving crews and ground personnel during Shuttle/Mir space missions.

    PubMed

    Kanas, N; Salnitskiy, V; Grund, E M; Gushin, V; Weiss, D S; Kozerenko, O; Sled, A; Marmar, C R

    2000-09-01

    Anecdotal reports from space and results from simulation studies on Earth suggest that interpersonal and cultural issues will have an impact on the interactions of crewmembers and mission control personnel during future long-duration space missions. To evaluate this impact we studied 5 astronauts, 8 cosmonauts, and 42 American and 16 Russian mission control personnel who participated in the Shuttle/Mir space program. Subjects completed questions from the Profile of Mood States, the Group Environment Scale, and the Work Environment Scale on a weekly basis during the missions. Subscale scores from these measures were analyzed using a two-way ANOVA to examine mean differences as a function of country (American vs. Russian), group (crewmember vs. ground personnel), and their interaction. Americans scored higher on measures of vigor and work pressure, and Russians scored higher on measures of managerial control, task orientation, physical comfort, self discovery, and leader support (which also showed a significant interaction effect). Mission control subjects scored higher than crewmembers on four measures of dysphoric emotions, but both groups scored significantly lower than published norms from other studies. There were significant interaction effects for subscales measuring leader support, expressiveness, and independence, with the American astronauts scoring the lowest of all comparison groups on all three subscales. In future long-duration space missions, countermeasures should focus on providing support for crewmembers from a culture in the minority, and crews should include more than one representative from this culture. Positive aspects of the interpersonal environment should be enhanced. The needs of mission control personnel should be addressed as well as those of crewmembers.

  13. Pilot cluster randomised controlled trial of flooring to reduce injuries from falls in wards for older people.

    PubMed

    Drahota, Amy Kim; Ward, Derek; Udell, Julie E; Soilemezi, Dia; Ogollah, Reuben; Higgins, Bernard; Dean, Taraneh P; Severs, Martin

    2013-09-01

    falls disproportionately affect older people, who are at increased risk of falls and injury. This pilot study investigates shock-absorbing flooring for fall-related injuries in wards for frail older people. we conducted a non-blinded cluster randomised trial in eight hospitals in England between April 2010 and August 2011. Each site allocated one bay as the 'study area', which was randomised via computer to intervention (8.3-mm thick Tarkett Omnisports EXCEL) or control (2-mm standard in situ flooring). Sites had an intervention period of 1 year. Anybody admitted to the study area was eligible. The primary outcome was the fall-related injury rate. Secondary outcomes were injury severity, fall rate and adverse events. during the intervention period, 226 participants were recruited to each group (219 and 223 were analysed in the intervention and control group, respectively). Of 35 falls (31 fallers) in the intervention group, 22.9% were injurious, compared with 42.4% of 33 falls (22 fallers) in the control group [injury incident rate ratio (IRR) = 0.58, 95% CI = 0.18-1.91]. There were no moderate or major injuries in the intervention group and six in the control group. The fall IRR was 1.07 (95% CI = 0.64-1.81). Staff at intervention sites raised concerns about pushing equipment, documenting one pulled back. future research should assess shock-absorbing flooring with better 'push/pull' properties and explore increased faller risk. We estimate a future trial will need 33,480-52,840 person bed-days per arm.

  14. Development and validation of a questionnaire assessing the perceived control in health care among older adults with care needs in the Netherlands.

    PubMed

    Claassens, L; Terwee, C B; Deeg, D J H; Broese van Groenou, M I; Widdershoven, G A M; Huisman, M

    2016-04-01

    In response to the increased emphasis placed on older people's self-reliance in many welfare societies, we aimed to develop and validate a measurement instrument, assessing perceived control in health care among older adults with care needs. The target group consists of older people who live (semi-)independently and use professional health care, with or without informal care. Phase I (development) of the study consisted of the construction of the instrument based on the input from a variety of stakeholders. Phase II (validation) entailed a quantitative study in a sample of 247 respondents selected from the Longitudinal Aging Study Amsterdam, to assess the instrument's construct validity (structural validity and hypotheses testing) and reliability (internal consistency). The questionnaire consists of 29 items, related to organizing professional care, communication with care professionals, health management in the home situation, planning (more) complex care in the future, and perceived support from the social network. Based on a factor analysis, we identified three subscales: (I.) 'perceived personal control in health care'; (II.) 'anticipated personal control regarding future health care'; and (III.) 'perceived support from the social network,' with internal consistencies varying from Cronbach's α = .71 to .90. Factor I was associated with mastery, self-efficacy, self-esteem (r = .31-.35) and factor III with social loneliness (r = -.42). Factor II correlated less strongly with mastery, self-efficacy, and self-esteem (r < .30). Our questionnaire revealed sufficient construct validity and internal consistency. The instrument provides a basis for further quantitative research regarding control, especially in relation to health care-related outcomes.

  15. Doppler Echocardiography Assessment of Aortic Stiffness in Female Adolescents with Anorexia Nervosa.

    PubMed

    Escudero, Carolina A; Potts, James E; Lam, Pei-Yoong; De Souza, Astrid M; Mugford, Gerald J; Sandor, George G S

    2018-03-17

    Anorexia nervosa (AN) is associated with abnormalities in biomarkers of cardiovascular risk. Arterial stiffness, as measured by pulse-wave velocity (PWV), is also a risk factor for cardiovascular disease. The aims of this study were to determine the stiffness of the aorta in female adolescents with AN and to determine if either the severity or the type of AN was associated with PWV. This was a retrospective case-control study. Adolescent patients with a clinical diagnosis of AN were included. Aortic diameter and pulse-wave transit time over a portion of the thoracic aorta were measured using Doppler echocardiography, and PWV was calculated. There were 94 female patients with AN and 60 adolescent female control subjects. There was no significant difference in age between patients with AN and control subjects (15.5 ± 1.7 vs 15.1 ± 2.6 years, P = .220). Body mass index (16.0 ± 2.4 vs 19.7 ± 2.7 kg/m 2 , P < .001) and body mass index percentile (9.4 ± 15.6 vs 45.5 ± 26.2, P < .001) were significantly lower for patients with AN than control subjects. PWV (443 ± 106 vs 383 ± 77 cm/sec, P < .001) was significantly higher in patients with AN than control subjects. Similar differences from control subjects were found in patients with AN with both lower and higher body mass index percentiles and also in patients with AN with the restrictive or the binge-purge subtype. Female adolescents with AN have increased aortic stiffness compared with control subjects. This study suggests that patients with AN may be at increased risk for future cardiovascular disease. Future studies are required to determine the reversibility of these changes with weight restoration. Copyright © 2018 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.

  16. The anticipated transition to adulthood: effects of culture and individual experience on Polish and Finnish adolescents' future orientations.

    PubMed

    Trempala, J; Malmberg, L E

    1998-05-01

    The purpose of this study was to describe the effect of a set of individual resources and cultural factors on adolescents' probability estimations of the occurrence of positive future events in three life domains: education, occupation, and family. The hypothesis was that the effects of culture and individual resources are interwoven in the formation process of future orientation. The sample consisted of 352 17-year-old Polish and Finnish girls and boys from vocational and upper secondary schools. The 78-item questionnaire developed by the authors was used to measure different aspects of future orientation (probability, valence, and extension of future events in three life domains) and individual resources (self-esteem, control beliefs, and social knowledge about normatively and the generation gap). Data analysis showed that culture separately affected individual resources and adolescents' expectations. However, the results broadly confirmed the thesis that the culture has a limited effect on adolescents' expectations of the occurrence of future events. Moreover, these data suggested that the influence of sociocultural differences on adolescents' probability estimations is indirect. In the context of the presented data, the authors discuss their model of future orientation.

  17. Implicit Depression and Hopelessness in Remitted Depressed Individuals

    PubMed Central

    Meites, Tiffany M.; Deveney, Christen M.; Steele, Katherine T.; Holmes, Avram J.; Pizzagalli, Diego A.

    2008-01-01

    Cognitive theories of depression posit that automatically activated cognitive schemas, including negative thoughts about the self and the future, predispose individuals to develop depressive disorders. However, prior research has largely examined these constructs using explicit tests in currently depressed individuals. Using the Implicit Association Test (IAT), the present study examined automatic associations between the self and mood state (“depression IAT”) and between the future and mood state (“hopelessness IAT”) before and after a negative mood induction in 19 remitted depressed individuals and 23 healthy controls. In the depression IAT, remitted depressed participants exhibited an overall lower tendency to associate themselves with happiness relative to the healthy controls before the mood induction. Control, but not remitted depressed, participants’ automatic associations between the self and happiness diminished following the mood induction. Contrary to our hypotheses, no significant findings emerged when considering the hopelessness IAT. Consistent with prior studies, no significant correlations emerged between implicit and explicit biases, suggesting that these measures probe different processes. Results extend prior IAT research by documenting the presence of a reduced tendency to associate the self with happiness in a sample at increased risk for depression. PMID:18692169

  18. 17 CFR 1.17 - Minimum financial requirements for futures commission merchants and introducing brokers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... internal risk management control system of the futures commission merchant; a description of how the... section; and (ii)(A) The readily marketable collateral is in the possession or control of the applicant or... accepted accounting principles. For the purposes of computing “net capital”, the term “liabilities”: (i...

  19. Evaluation of the effect of MnPASS lane design on mobility and safety : final report.

    DOT National Transportation Integrated Search

    2014-06-01

    Dynamically priced High Occupancy Toll (HOT) lanes have been recently added to the traffic operations arsenal in : an attempt to preserve infrastructure investment in the future by maintaining a control on demand. This study : focuses on the operatio...

  20. Running injuries in novice runners enrolled in different training interventions: a pilot randomized controlled trial.

    PubMed

    Baltich, J; Emery, C A; Whittaker, J L; Nigg, B M

    2017-11-01

    The purpose of this trial was to evaluate injury risk in novice runners participating in different strength training interventions. This was a pilot randomized controlled trial. Novice runners (n = 129, 18-60 years old, <2 years recent running experience) were block randomized to one of three groups: a "resistance" strength training group, a "functional" strength training group, or a stretching "control" group. The primary outcome was running related injury. The number of participants with complaints and the injury rate (IR = no. injuries/1000 running hours) were quantified for each intervention group. For the first 8 weeks, participants were instructed to complete their training intervention three to five times a week. The remaining 4 months was a maintenance period. NCT01900262. A total of 52 of the 129 (40%) novice runners experienced at least one running related injury: 21 in the functional strength training program, 16 in the resistance strength training program and 15 in the control stretching program. Injury rates did not differ between study groups [IR = 32.9 (95% CI 20.8, 49.3) in the functional group, IR = 31.6 (95% CI 18.4, 50.5) in the resistance group, and IR = 26.7 (95% CI 15.2, 43.2)] in the control group. Although this was a pilot assessment, home-based strength training did not appear to alter injury rates compared to stretching. Future studies should consider methods to minimize participant drop out to allow for the assessment of injury risk. Injury risk in novice runners based on this pilot study will inform the development of future larger studies investigating the impact of injury prevention interventions. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Single pilot scanning behavior in simulated instrument flight

    NASA Technical Reports Server (NTRS)

    Pennington, J. E.

    1979-01-01

    A simulation of tasks associated with single pilot general aviation flight under instrument flight rules was conducted as a baseline for future research studies on advanced flight controls and avionics. The tasks, ranging from simple climbs and turns to an instrument landing systems approach, were flown on a fixed base simulator. During the simulation the control inputs, state variables, and the pilots visual scan pattern including point of regard were measured and recorded.

  2. A Study on Predictive Analytics Application to Ship Machinery Maintenance

    DTIC Science & Technology

    2013-09-01

    Looking at the nature of the time series forecasting method , it would be better applied to offline analysis . The application for real- time online...other system attributes in future. Two techniques of statistical analysis , mainly time series models and cumulative sum control charts, are discussed in...statistical tool employed for the two techniques of statistical analysis . Both time series forecasting as well as CUSUM control charts are shown to be

  3. Methodological Issues in Research on Web-Based Behavioral Interventions

    PubMed Central

    Danaher, Brian G; Seeley, John R

    2013-01-01

    Background Web-based behavioral intervention research is rapidly growing. Purpose We review methodological issues shared across Web-based intervention research to help inform future research in this area. Methods We examine measures and their interpretation using exemplar studies and our research. Results We report on research designs used to evaluate Web-based interventions and recommend newer, blended designs. We review and critique methodological issues associated with recruitment, engagement, and social validity. Conclusions We suggest that there is value to viewing this burgeoning realm of research from the broader context of behavior change research. We conclude that many studies use blended research designs, that innovative mantling designs such as the Multiphase Optimization Strategy and Sequential Multiple Assignment Randomized Trial methods hold considerable promise and should be used more widely, and that Web-based controls should be used instead of usual care or no-treatment controls in public health research. We recommend topics for future research that address participant recruitment, engagement, and social validity. PMID:19806416

  4. Anaplastic lymphoma kinase inhibitors in brain metastases from ALK+ non-small cell lung cancer: hitting the target even in the CNS.

    PubMed

    Klempner, Samuel J; Ou, Sai-Hong Ignatius

    2015-06-01

    The paradigm shift occurring in non-small cell lung cancer (NSCLC) is encapsulated by the management of patients harboring oncogenic anaplastic lymphoma kinase (ALK) rearrangements. The unprecedented improvements in patient outcomes resulting from ALK-directed therapy have led to the appreciation of patterns of disease progression. Early studies have suggested that some tyrosine kinase inhibitors (TKIs), including ALK TKIs, inefficiently penetrated the blood brain barrier. With the increasing appreciation of the CNS as a sanctuary site in ALK TKI-treated patients, there is increasing focus and importance on the prevention and control of CNS metastases in ALK-rearranged NSCLC. The spectrum of CNS activity is variable among the currently available ALK TKI therapies and further studies are ongoing. In the following review we discuss the ability of current and future ALK inhibitors (ALK-i) to control and prevent CNS progression in patients with ALK-rearranged NSCLC. The potential implications for TKI sequencing and important future research directions are discussed.

  5. A dark past, a restrained present, and an apocalyptic future: time perspective, personality, and life satisfaction among anorexia nervosa patients

    PubMed Central

    Granjard, Alexandre; Lundblad, Suzanna; Archer, Trevor

    2017-01-01

    Background Despite reporting low levels of well-being, anorexia nervosa patients express temperament traits (e.g., extraversion and persistence) necessary for high levels of life satisfaction. Nevertheless, among individuals without eating disorders, a balanced organization of the flow of time, influences life satisfaction beyond temperamental dispositions. A balanced time perspective is defined as: high past positive, low past negative, high present hedonistic, low present fatalistic, and high future. We investigated differences in time perspective dimensions, personality traits, and life satisfaction between anorexia nervosa patients and matched controls. We also investigated if the personality traits and the outlook on time associated to positive levels of life satisfaction among controls also predicted anorexia patients’ life satisfaction. Additionally, we investigated if time perspective dimensions predicted life satisfaction beyond personality traits among both patients and controls. Method A total of 88 anorexia nervosa patients from a clinic in the West of Sweden and 111 gender-age matched controls from a university in the West of Sweden participated in the Study. All participants responded to the Zimbardo Time Perspective Inventory, the Ten Item Personality Inventory, and the Temporal Satisfaction with Life Scale. Results A t-test showed that patients scored higher in the past negative, the present fatalistic, and the future dimensions, lower in the past positive and the present hedonistic dimensions, higher in conscientiousness, extraversion, and agreeableness, and lower in life satisfaction. Regression analyses showed that life satisfaction was predicted by openness to experience and emotional stability for controls and by emotional stability among patients. When time dimensions were entered in the regression, emotional stability and the past negative and past positive time dimensions predicted life satisfaction among controls, but only the past positive and present hedonistic time dimensions predicted life satisfaction among patients. Conclusion Anorexia patients were less satisfied with life despite being more conscientious, social, and agreeable than controls. Moreover, compared to controls, patients had an unbalanced time perspective: a dark view of the past (i.e., high past negative), a restrained present (i.e., low present hedonistic) and an apocalyptic view of the future (i.e., high present fatalistic). It is plausible to suggest that, therapeutic interventions should focus on empowering patients to cultivate a sentimental and positive view of the past (i.e., high past positive) and the desire to experience pleasure without concern for future consequences (i.e., high present hedonistic) so that they can make self-directed and flexible choices for their own well-being. Such interventions might have effects on life satisfaction beyond the patients’ temperamental disposition. PMID:28929023

  6. Current and Future Developments in Air Traffic Control

    NASA Technical Reports Server (NTRS)

    Jackson, Joseph; Green, Steven M.

    1999-01-01

    Current and future energy demands, end uses, and cost used to characterize typical applications services in the industrial sector of the United States are examined. A review and evaluation of existing industrial energy data bases was undertaken to assess their potential for supporting SERI research market suitability analysis; (2) market development; (3) end use matching; (4) industrial application studies; and (5) identification of cost and performance goals for solar systems and typical information requirements for industrial energy end use. The focus was on fuels and electric energy used for heat and power purchased by the manufacturing subsector and listed by 2, 3, and 4 digit SIC, primary fuel. The effects of federal and state industrial energy conservation programs on future industrial sector demands were assessed.

  7. Advanced Curation Activities at NASA: Implications for Astrobiological Studies of Future Sample Collections

    NASA Technical Reports Server (NTRS)

    McCubbin, F. M.; Evans, C. A.; Fries, M. D.; Harrington, A. D.; Regberg, A. B.; Snead, C. J.; Zeigler, R. A.

    2017-01-01

    The Astromaterials Acquisition and Curation Office (henceforth referred to herein as NASA Curation Office) at NASA Johnson Space Center (JSC) is responsible for curating all of NASA's extraterrestrial samples. Under the governing document, NASA Policy Directive (NPD) 7100.10F JSC is charged with curation of all extraterrestrial material under NASA control, including future NASA missions. The Directive goes on to define Curation as including documentation, preservation, preparation, and distribution of samples for re-search, education, and public outreach. Here we briefly describe NASA's astromaterials collections and our ongoing efforts related to enhancing the utility of our current collections as well as our efforts to prepare for future sample return missions. We collectively refer to these efforts as advanced curation.

  8. Epidemiologic studies of electric and magnetic fields and cancer: Strategies for extending knowledge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Savitz, D.A.

    1993-12-01

    Epidemiologic research concerning electric and magnetic fields in relation to cancer has focused on the potential etiologic roles of residential exposure on childhood cancer and occupational exposure on adult leukemia and brain cancer. Future residential studies must concentrate on exposure assessment that is enhanced by developing models of historical exposure, assessment of the relation between magnetic fields and wire codes, and consideration of alternate exposure indices. Study design issues deserving attention include possible biases in random digit dialing control selection, consideration of the temporal course of exposure and disease, and acquisition of the necessary information to assess the potential valuemore » of ecologic studies. Highest priorities are comprehensive evaluation of exposure patterns and sources and examination of the sociology and geography of residential wire codes. Future occupational studies should also concentrate on improved exposure assessment with increased attention to nonutility worker populations and development of historical exposure indicators that are superior to job titles alone. Potential carcinogens in the workplace that could act as confounders need to be more carefully examined. The temporal relation between exposure and disease and possible effect modification by other workplace agents should be incorporated into future studies. The most pressing need is for measurement of exposure patterns in a variety of worker populations and performance of traditional epidemiologic evaluations of cancer occurrence. The principal source of bias toward the null is nondifferential misclassification of exposure with improvements expected to enhance any true etiologic association that is present. Biases away from the null might include biased control selection in residential studies and chemical carcinogens acting as confounders in occupational studies. 51 refs., 1 tab.« less

  9. Examination of value of the future and health beliefs to explain dietary and physical activity behaviors.

    PubMed

    Garza, Kimberly Bosworth; Harris, Carole V; Bolding, Mark S

    2013-01-01

    Studies have shown a negative association between value of the future (preference for long-term vs. short-term rewards) and harmful addictive behaviors; however, research in the area of preventive behaviors is limited and has shown conflicting results. The primary objectives were: (1) to examine the association among value of the future and diet and physical activity (PA) behaviors, and (2) to assess whether value of the future explained additional variance in behaviors after controlling for theory-based health beliefs related to coronary heart disease (CHD). An online survey was conducted in adults (N = 172) with no prior history of CHD. A delay discounting task was administered to measure value of the future. Questionnaire items were based on the Health Belief Model (HBM) and included CHD knowledge, perceived risk, perceived severity, perceived benefits of and barriers to behavior change, self-efficacy, cues to action, diet and PA behaviors and demographic variables. High value of the future was associated with younger age, lower BMI, more healthful diet, and increased PA. After controlling for HBM components and demographics, value of the future did not explain any additional variance in diet or PA behaviors. Significant predictors of healthful diet included female gender (P = .013), increased age (P = .029), greater than high school education (P = .023), greater diet-related self-efficacy (P = .021), and not having received a healthcare provider recommendation to improve diet (P = .018). Significant predictors of PA level included income between $20,000 and $69,999 (P = .014), greater exercise-related self-efficacy (P < .001) and not having received a healthcare provider recommendation to increase levels of PA (P = .015). Behaviors to prevent CHD may be associated with a person's outlook on the future; however, self-efficacy was a stronger predictor of behavior. These findings support recommendations for enhancement of diet- and PA-related self-efficacy and problem-solving to address myopia in terms of long-term health benefits. Copyright © 2013 Elsevier Inc. All rights reserved.

  10. The Complexity of Standing Postural Sway Associates with Future Falls in Community-Dwelling Older Adults: The MOBILIZE Boston Study.

    PubMed

    Zhou, Junhong; Habtemariam, Daniel; Iloputaife, Ikechukwu; Lipsitz, Lewis A; Manor, Brad

    2017-06-07

    Standing postural control is complex, meaning that it is dependent upon numerous inputs interacting across multiple temporal-spatial scales. Diminished physiologic complexity of postural sway has been linked to reduced ability to adapt to stressors. We hypothesized that older adults with lower postural sway complexity would experience more falls in the future. 738 adults aged ≥70 years completed the Short Physical Performance Battery test (SPPB) test and assessments of single and dual-task standing postural control. Postural sway complexity was quantified using multiscale entropy. Falls were subsequently tracked for 48 months. Negative binomial regression demonstrated that older adults with lower postural sway complexity in both single and dual-task conditions had higher future fall rate (incident rate ratio (IRR) = 0.98, p = 0.02, 95% Confidence Limits (CL) = 0.96-0.99). Notably, participants in the lowest quintile of complexity during dual-task standing suffered 48% more falls during the four-year follow-up as compared to those in the highest quintile (IRR = 1.48, p = 0.01, 95% CL = 1.09-1.99). Conversely, traditional postural sway metrics or SPPB performance did not associate with future falls. As compared to traditional metrics, the degree of multi-scale complexity contained within standing postural sway-particularly during dual task conditions- appears to be a better predictor of future falls in older adults.

  11. Design and implementation of robust decentralized control laws for the ACES structure at Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Collins, Emmanuel G., Jr.; Phillips, Douglas; Hyland, David C.

    1990-01-01

    An experiment was conducted to design controllers that would provide substantial reduction of line-of-sight control errors. The satisfaction of this objective required the controllers to attenuate the beam vibration significantly. Particular emphasis was placed on controller simplicity (i.e., reduced-order and decentralized controller architectures). Complexity reduction in control law implementation is of paramount interest due to stringent limitations on throughput of even state-of-the-art space qualified processors. The results of this experiment successfully demonstrate active vibrator control for a flexible structure. The testbed is the ACES structure at the NASA Marshall Space Flight Center. The ACES structure is dynamically traceable to future space systems and especially allows the study of line-of-sight control issues.

  12. US Navy SHF SATCOM: Past, present and future

    NASA Astrophysics Data System (ADS)

    Bushnell, Christopher J.

    1994-06-01

    This thesis discusses the Navy's Super High Frequency Satellite Communications (SHF SATCOM) capabilities prior to Desert Shield/Desert Storm, and the requirements for future systems that were generated due to Navy SATCOM shortcomings during the Gulf War. The four-phased evolutionary approach the Navy has designed (based on post-war requirements) to provide itself with a medium for SHF SATCOM into the 21st Century, as well as the Defense Satellite Communications Systems (DSCS), are examined in detail. Decreasing defense budgets have begun to have a significant impact on future military satellite communication (MILSATCOM) systems. A cost comparison between utilization of DSCS III satellites and the INMARSAT commercial SATCOM system is presented. Recommended improvements to current MILSATCOM procedures and training practices are proposed that could improve operational C4I capabilities. Finally, this study determines that future SATCOM architectures should include a mixture of commercial systems and MILSATCOM systems to provide both cost savings and command and control protection.

  13. Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease.

    PubMed

    Rolinski, Michal; Griffanti, Ludovica; Piccini, Paola; Roussakis, Andreas A; Szewczyk-Krolikowski, Konrad; Menke, Ricarda A; Quinnell, Timothy; Zaiwalla, Zenobia; Klein, Johannes C; Mackay, Clare E; Hu, Michele T M

    2016-08-01

    SEE POSTUMA DOI101093/AWW131 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: Resting state functional magnetic resonance imaging dysfunction within the basal ganglia network is a feature of early Parkinson's disease and may be a diagnostic biomarker of basal ganglia dysfunction. Currently, it is unclear whether these changes are present in so-called idiopathic rapid eye movement sleep behaviour disorder, a condition associated with a high rate of future conversion to Parkinson's disease. In this study, we explore the utility of resting state functional magnetic resonance imaging to detect basal ganglia network dysfunction in rapid eye movement sleep behaviour disorder. We compare these data to a set of healthy control subjects, and to a set of patients with established early Parkinson's disease. Furthermore, we explore the relationship between resting state functional magnetic resonance imaging basal ganglia network dysfunction and loss of dopaminergic neurons assessed with dopamine transporter single photon emission computerized tomography, and perform morphometric analyses to assess grey matter loss. Twenty-six patients with polysomnographically-established rapid eye movement sleep behaviour disorder, 48 patients with Parkinson's disease and 23 healthy control subjects were included in this study. Resting state networks were isolated from task-free functional magnetic resonance imaging data using dual regression with a template derived from a separate cohort of 80 elderly healthy control participants. Resting state functional magnetic resonance imaging parameter estimates were extracted from the study subjects in the basal ganglia network. In addition, eight patients with rapid eye movement sleep behaviour disorder, 10 with Parkinson's disease and 10 control subjects received (123)I-ioflupane single photon emission computerized tomography. We tested for reduction of basal ganglia network connectivity, and for loss of tracer uptake in rapid eye movement sleep behaviour disorder and Parkinson's disease relative to each other and to controls. Connectivity measures of basal ganglia network dysfunction differentiated both rapid eye movement sleep behaviour disorder and Parkinson's disease from controls with high sensitivity (96%) and specificity (74% for rapid eye movement sleep behaviour disorder, 78% for Parkinson's disease), indicating its potential as an indicator of early basal ganglia dysfunction. Rapid eye movement sleep behaviour disorder was indistinguishable from Parkinson's disease on resting state functional magnetic resonance imaging despite obvious differences on dopamine transported single photon emission computerized tomography. Basal ganglia connectivity is a promising biomarker for the detection of early basal ganglia network dysfunction, and may help to identify patients at risk of developing Parkinson's disease in the future. Future risk stratification using a polymodal approach could combine basal ganglia network connectivity with clinical and other imaging measures, with important implications for future neuroprotective trials in rapid eye movement sleep behaviour disorder. © The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain.

  14. Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson’s disease

    PubMed Central

    Rolinski, Michal; Griffanti, Ludovica; Piccini, Paola; Roussakis, Andreas A.; Szewczyk-Krolikowski, Konrad; Menke, Ricarda A.; Quinnell, Timothy; Zaiwalla, Zenobia; Klein, Johannes C.; Mackay, Clare E.

    2016-01-01

    Abstract See Postuma (doi:10.1093/aww131) for a scientific commentary on this article. Resting state functional magnetic resonance imaging dysfunction within the basal ganglia network is a feature of early Parkinson’s disease and may be a diagnostic biomarker of basal ganglia dysfunction. Currently, it is unclear whether these changes are present in so-called idiopathic rapid eye movement sleep behaviour disorder, a condition associated with a high rate of future conversion to Parkinson’s disease. In this study, we explore the utility of resting state functional magnetic resonance imaging to detect basal ganglia network dysfunction in rapid eye movement sleep behaviour disorder. We compare these data to a set of healthy control subjects, and to a set of patients with established early Parkinson’s disease. Furthermore, we explore the relationship between resting state functional magnetic resonance imaging basal ganglia network dysfunction and loss of dopaminergic neurons assessed with dopamine transporter single photon emission computerized tomography, and perform morphometric analyses to assess grey matter loss. Twenty-six patients with polysomnographically-established rapid eye movement sleep behaviour disorder, 48 patients with Parkinson’s disease and 23 healthy control subjects were included in this study. Resting state networks were isolated from task-free functional magnetic resonance imaging data using dual regression with a template derived from a separate cohort of 80 elderly healthy control participants. Resting state functional magnetic resonance imaging parameter estimates were extracted from the study subjects in the basal ganglia network. In addition, eight patients with rapid eye movement sleep behaviour disorder, 10 with Parkinson’s disease and 10 control subjects received 123I-ioflupane single photon emission computerized tomography. We tested for reduction of basal ganglia network connectivity, and for loss of tracer uptake in rapid eye movement sleep behaviour disorder and Parkinson’s disease relative to each other and to controls. Connectivity measures of basal ganglia network dysfunction differentiated both rapid eye movement sleep behaviour disorder and Parkinson’s disease from controls with high sensitivity (96%) and specificity (74% for rapid eye movement sleep behaviour disorder, 78% for Parkinson’s disease), indicating its potential as an indicator of early basal ganglia dysfunction. Rapid eye movement sleep behaviour disorder was indistinguishable from Parkinson’s disease on resting state functional magnetic resonance imaging despite obvious differences on dopamine transported single photon emission computerized tomography. Basal ganglia connectivity is a promising biomarker for the detection of early basal ganglia network dysfunction, and may help to identify patients at risk of developing Parkinson’s disease in the future. Future risk stratification using a polymodal approach could combine basal ganglia network connectivity with clinical and other imaging measures, with important implications for future neuroprotective trials in rapid eye movement sleep behaviour disorder. PMID:27297241

  15. Conflict Probe Concepts Analysis in Support of Free Flight

    NASA Technical Reports Server (NTRS)

    Warren, Anthony W.; Schwab, Robert W.; Geels, Timothy J.; Shakarian, Arek

    1997-01-01

    This study develops an operational concept and requirements for en route Free Flight using a simulation of the Cleveland Air Route Traffic Control Center, and develops requirements for an automated conflict probe for use in the Air Traffic Control (ATC) Centers. In this paper, we present the results of simulation studies and summarize implementation concepts and infrastructure requirements to transition from the current air traffic control system to mature Free Right. The transition path to Free Flight envisioned in this paper assumes an orderly development of communications, navigation, and surveillance (CNS) technologies based on results from our simulation studies. The main purpose of this study is to provide an overall context and methodology for evaluating airborne and ground-based requirements for cooperative development of the future ATC system.

  16. Piloting a psycho-social intervention for incarcerated women with trauma histories: lessons learned and future recommendations.

    PubMed

    Liebman, Rachel E; Burnette, Mandi L; Raimondi, Christina; Nichols-Hadeed, Corey; Merle, Patricia; Cerulli, Catherine

    2014-08-01

    Trauma and related mental health disorders are common among incarcerated women, but empirically sound mental health interventions are lacking in prisons. Implementing such interventions is fraught with legal and logistical barriers. These barriers can be particularly detrimental for trauma-specific interventions given the unique needs of trauma survivors, yet there is little documentation of these issues or how to address them. This study describes a pilot study of an 8-week, strengths-based, trauma-focused intervention for 26 incarcerated women. Women reported considerable mental health problems and trauma. The study highlights the importance of adapting stringent research methodologies for prison-based trauma interventions. For instance, women with trauma were reluctant to participate in an intervention advertised as trauma-based. Moreover, a randomized wait list control design was unfeasible because women wanted the support of their friends when discussing trauma and could not control their schedules 9 weeks in advance. Ultimately, this work may inform future efforts to implement effective trauma-based interventions behind prison walls. © The Author(s) 2013.

  17. Survey of decentralized control methods. [for large scale dynamic systems

    NASA Technical Reports Server (NTRS)

    Athans, M.

    1975-01-01

    An overview is presented of the types of problems that are being considered by control theorists in the area of dynamic large scale systems with emphasis on decentralized control strategies. Approaches that deal directly with decentralized decision making for large scale systems are discussed. It is shown that future advances in decentralized system theory are intimately connected with advances in the stochastic control problem with nonclassical information pattern. The basic assumptions and mathematical tools associated with the latter are summarized, and recommendations concerning future research are presented.

  18. Mapping out past and future minds: The perceived trajectory of rationality versus emotionality over time.

    PubMed

    O'Brien, Ed

    2015-06-01

    Who do we see when envisioning our "past self" and "future self"? Extant research finds a motivation to perceive improvement over time, such that past selves are seen as worse versions, and future selves as better versions, of current selves. However, the broader components comprising "worse" or "better" beyond domain-specific achievement (e.g., "Last year I failed at dieting, but next year I'll succeed") are less well understood. Are there more general qualities ascribed to the person we recall versus imagine being? Six studies suggest so, extending the 2-dimensional mind perception framework to the self: Past selves seem to possess highly emotional but not very rational minds, whereas future selves seem to possess highly rational but not very emotional minds (Studies 1a, 1b, 1c). Consistent with motivated improvement, this asymmetry does not emerge in evaluating others and applies uniquely to self-judgment (Study 2). Thus, our pervasive belief in changing for the "better" specifically means becoming more rational types of people. This observation has asymmetric consequences. Participants who brought to mind future selves sought intellectual enrichment (Study 3) and performed better on a self-control task (Study 4); however, participants who brought to mind past selves sought emotional enrichment and performed better on the same task when allegedly measuring enjoyment. These findings build a bridge between mind perception and intertemporal dynamics, raising novel implications for the present. Thinking about the future may not uniformly "improve" decisions and behaviors; rather, it mostly facilitates rational-related pursuits, whereas thinking about the past may enhance feeling-related experiences. (c) 2015 APA, all rights reserved).

  19. Alternative futures of proactive tools for a citizen's own wellbeing.

    PubMed

    Meristö, Tarja; Tuohimaa, Hanna; Leppimäki, Sami; Laitinen, Jukka

    2009-01-01

    The aim of this paper is to create the basis for a vision of an empowered citizen who can control his/her life, especially in relation to health and personal wellbeing with the use of new ICT-tools. The methods used in the study are based on futures studies, especially on scenario methodology. Alternative future paths, i.e. scenarios are constructed using the scenario filter model that we have developed, with market, technology and society perspectives. Scenarios not resulting in the vision are described in what if - analysis as well. The scenarios are combined with Viherä's model on citizen's skills, access and motivation to use new ICT-tools. The concept COPER is targeted to different user groups with an adaptable user interface and its development is user centered. We will consider the effects and the appropriate elements of COPER in every scenario, as well as the possibilities and challenges nursing will confront. As a result we will gain information of the characteristic of COPER that advance the vision. For the future development of COPER the alternative scenarios give the basis for flexibility planning, too.

  20. Distinguishing between unipolar depression and bipolar depression: current and future clinical and neuroimaging perspectives.

    PubMed

    Cardoso de Almeida, Jorge Renner; Phillips, Mary Louise

    2013-01-15

    Differentiating bipolar disorder (BD) from recurrent unipolar depression (UD) is a major clinical challenge. Main reasons for this include the higher prevalence of depressive relative to hypo/manic symptoms during the course of BD illness and the high prevalence of subthreshold manic symptoms in both BD and UD depression. Identifying objective markers of BD might help improve accuracy in differentiating between BD and UD depression, to ultimately optimize clinical and functional outcome for all depressed individuals. Yet, only eight neuroimaging studies to date have directly compared UD and BD depressed individuals. Findings from these studies suggest more widespread abnormalities in white matter connectivity and white matter hyperintensities in BD than UD depression, habenula volume reductions in BD but not UD depression, and differential patterns of functional abnormalities in emotion regulation and attentional control neural circuitry in the two depression types. These findings suggest different pathophysiologic processes, especially in emotion regulation, reward, and attentional control neural circuitry in BD versus UD depression. This review thereby serves as a call to action to highlight the pressing need for more neuroimaging studies, using larger samples sizes, comparing BD and UD depressed individuals. These future studies should also include dimensional approaches, studies of at-risk individuals, and more novel neuroimaging approaches, such as connectivity analysis and machine learning. Ultimately, these approaches might provide biomarkers to identify individuals at future risk for BD versus UD and biological targets for more personalized treatment and new treatment developments for BD and UD depression. Copyright © 2013 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  1. Examining the relationship between religiosity and self-control as predictors of prison deviance.

    PubMed

    Kerley, Kent R; Copes, Heith; Tewksbury, Richard; Dabney, Dean A

    2011-12-01

    The relationship between religiosity and crime has been the subject of much empirical debate and testing over the past 40 years. Some investigators have argued that observed relationships between religion and crime may be spurious because of self-control, arousal, or social control factors. The present study offers the first investigation of religiosity, self-control, and deviant behavior in the prison context. We use survey data from a sample of 208 recently paroled male inmates to test the impact of religiosity and self-control on prison deviance. The results indicate that two of the three measures of religiosity may be spurious predictors of prison deviance after accounting for self-control. Participation in religious services is the only measure of religiosity to significantly reduce the incidence of prison deviance when controlling for demographic factors, criminal history, and self-control. We conclude with implications for future studies of religiosity, self-control, and deviance in the prison context.

  2. Examining the Relationship Between Religiosity and Self-Control as Predictors of Prison Deviance.

    PubMed

    Kerley, Kent R; Copes, Heith; Tewksbury, Richard; Dabney, Dean A

    2010-11-29

    The relationship between religiosity and crime has been the subject of much empirical debate and testing over the past 40 years. Some investigators have argued that observed relationships between religion and crime may be spurious because of self-control, arousal, or social control factors. The present study offers the first investigation of religiosity, self-control, and deviant behavior in the prison context. We use survey data from a sample of 208 recently paroled male inmates to test the impact of religiosity and self-control on prison deviance. The results indicate that two of the three measures of religiosity may be spurious predictors of prison deviance after accounting fovr self-control. Participation in religious services is the only measure of religiosity to significantly reduce the incidence of prison deviance when controlling for demographic factors, criminal history, and self-control. We conclude with implications for future studies of religiosity, self-control, and deviance in the prison context.

  3. Anxious or Depressed and Still Happy?

    PubMed Central

    Spinhoven, Philip; Elzinga, Bernet M.; Giltay, Erik; Penninx, Brenda W. J. H.

    2015-01-01

    This study aimed to examine cross-sectionally to what extent persons with higher symptom levels or a current or past emotional disorder report to be less happy than controls and to assess prospectively whether time-lagged measurements of extraversion and neuroticism predict future happiness independent of time-lagged measurements of emotional disorders or symptom severity. A sample of 2142 adults aged 18–65, consisting of healthy controls and persons with current or past emotional disorder according to DSM-IV criteria completed self-ratings for happiness and emotional well-being and symptom severity. Lagged measurements of personality, symptom severity and presence of anxiety and depressive disorder at T0 (year 0), T2 (year 2) and T4 (year 4) were used to predict happiness and emotional well-being at T6 (year 6) controlling for demographics. In particular persons with more depressive symptoms, major depressive disorder, social anxiety disorder and comorbid emotional disorders reported lower levels of happiness and emotional well-being. Depression symptom severity and to a lesser extent depressive disorder predicted future happiness and emotional well-being at T6. Extraversion and to a lesser extent neuroticism also consistently forecasted future happiness and emotional well-being independent of concurrent lagged measurements of emotional disorders and symptoms. A study limitation is that we only measured happiness and emotional well-being at T6 and our measures were confined to hedonistic well-being and did not include psychological and social well-being. In sum, consistent with the two continua model of emotional well-being and mental illness, a ‘happy’ personality characterized by high extraversion and to a lesser extent low neuroticism forecasts future happiness and emotional well-being independent of concurrently measured emotional disorders or symptom severity levels. Boosting positive emotionality may be an important treatment goal for persons personally inclined to lower levels of happiness. PMID:26461261

  4. How Important Is ‘Accuracy’ of Surrogate Decision-Making for Research Participation?

    PubMed Central

    Kim, Scott Y. H.; Kim, H. Myra; Ryan, Kerry A.; Appelbaum, Paul S.; Knopman, David S.; Damschroder, Laura; De Vries, Raymond

    2013-01-01

    Background There is a longstanding concern about the accuracy of surrogate consent in representing the health care and research preferences of those who lose their ability to decide for themselves. We sought informed, deliberative views of the older general public (≥50 years old) regarding their willingness to participate in dementia research and to grant leeway to future surrogates to choose an option contrary to their stated wishes. Methodology/Principal Findings 503 persons aged 50+ recruited by random digit dialing were randomly assigned to one of three groups: deliberation, education, or control. The deliberation group attended an all-day education/peer deliberation session; the education group received written information only. Participants were surveyed at baseline, after the deliberation session (or equivalent time), and one month after the session, regarding their willingness to participate in dementia research and to give leeway to surrogates, regarding studies of varying risk-benefit profiles (a lumbar puncture study, a drug randomized controlled trial, a vaccine randomized controlled trial, and an early phase gene transfer trial). At baseline, 48% (gene transfer scenario) to 92% (drug RCT) were willing to participate in future dementia research. A majority of respondents (57–71% depending on scenario) were willing to give leeway to future surrogate decision-makers. Democratic deliberation increased willingness to participate in all scenarios, to grant leeway in 3 of 4 scenarios (lumbar puncture, vaccine, and gene transfer), and to enroll loved ones in research in all scenarios. On average, respondents were more willing to volunteer themselves for research than to enroll their loved ones. Conclusions/Significance Most people were willing to grant leeway to their surrogates, and this willingness was either sustained or increased after democratic deliberation, suggesting that the attitude toward leeway is a reliable opinion. Eliciting a person’s current preferences about future research participation should also involve eliciting his or her leeway preferences. PMID:23382969

  5. Physical Activity Outcomes of Nurse-Delivered Lifestyle Interventions.

    PubMed

    Richards, Elizabeth A; Cai, Yun

    2016-02-01

    Promotion of physical activity has been a public health priority for decades. Over two million home healthcare nurses are at the front line to deliver effective health education and health promotion interventions in the United States. The purpose of this systematic review is to examine the effectiveness of nurse-delivered lifestyle physical interventions on physical activity outcomes conducted in home settings. Computerized database and ancestry search strategies located distinct intervention trials between 1990 and 2015. A total of eight quantitative studies were reviewed. Four of the eight studies were randomized control trials and four studies used an uncontrolled pretest-posttest design. The eight studies represented a total of 1,221 participants with mean ages from 43 to 81. Study sample sizes ranged from 16 to 504. Seven of the eight studies demonstrated modest effect of nurse-delivered home-based interventions on physical activity behaviors. Home-based physical activity promotion was most often incorporated into secondary prevention of postacute diseases, chronic disease management, or disease prevention/health promotion. Findings indicate that nurse-delivered home-based physical activity promotion show overall effectiveness in general adult populations. Possible effective intervention domains were also discussed in this review to guide future home-based health promotion. More large randomized controlled trials with longer study/follow-up periods and studies with cost-effectiveness data are warranted in future research.

  6. Design challenges in transdiagnostic psychotherapy research: Comparing Transdiagnostic Behavior Therapy (TBT) to existing evidence-based psychotherapy in veterans with affective disorders.

    PubMed

    Gros, Daniel F

    2015-07-01

    To address the limitations of disorder-specific approaches, newer transdiagnostic approaches to psychotherapy have been developed to provide a single treatment that is capable of addressing several, related disorders. However, the recruitment of multiple diagnoses presents many challenges to the traditional design of psychotherapy randomized controlled trials (RCTs). The goal of the manuscript is to present the challenges and rationale for designing a RCT for transdiagnostic treatment to inform and aid in the development of future investigations. A recently funded and ongoing RCT for Transdiagnostic Behavior Therapy (TBT) is used as an example to discuss the related design challenges. The TBT study involves the recruitment of 96 veteran participants with any of the following eight principal diagnoses: posttraumatic stress disorder, panic disorder, social anxiety disorder, obsessive compulsive disorder, generalized anxiety disorder, specific phobia, major depressive disorder, or persistent depressive disorder. Within the TBT study, participants will complete a semi-structured diagnostic interview and a series of transdiagnostic self-report measures to determine eligibility and assess baseline symptomatology. Qualifying participants will be randomized to TBT or control psychotherapy. Additional assessments will be completed at post-treatment and 6-month follow-up. Due to the transdiagnostic nature of the sample, adjustments to the recruitment and randomization procedures, selection of measures, selection of control psychotherapy, and analysis plan were required. These adjustments have implications to future trials on transdiagnostic psychotherapy protocols as well as future research in line with the transdiagnostic focus of the National Institute of Mental Health's Research Domain Criteria (RDoC) funding strategy. Published by Elsevier Inc.

  7. Advanced control technology and its potential for future transport aircraft

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The topics covered include fly by wire, digital control, control configured vehicles, applications to advanced flight vehicles, advanced propulsion control systems, and active control technology for transport aircraft.

  8. Early food for future health: a randomized controlled trial evaluating the effect of an eHealth intervention aiming to promote healthy food habits from early childhood.

    PubMed

    Helle, Christine; Hillesund, Elisabet Rudjord; Omholt, Mona Linge; Øverby, Nina Cecilie

    2017-09-20

    Childhood overweight and obesity is a global public health challenge. Primary prevention initiatives targeting parents have been called for to encourage a positive feeding environment and healthy eating habits that may lay a good foundation for future health. At the same time, there is a need for interventions which combine accessibility and scalability with cost effectiveness. Today's parents are extensive Internet-users, but only a few randomized controlled trials have investigated the use of Internet to promote healthy eating habits in early childhood. In Early Food for Future Health we have developed and will evaluate an Internet-based tool for parents of children between 6 and 12 months, aiming to increase knowledge about infant nutrition and foster protective feeding behavior. During springtime 2016, parents of children aged between 3 and 5 months were recruited through Norwegian child health centres and announcements on Facebook. After completing the baseline questionnaire, 718 parents were individually randomized to intervention- or control group. The intervention group received monthly emails with links to an age-appropriate web-site when their child was between 6 and 12 months. The control group received ordinary care from the child health centres. The data-collection is ongoing. All participants will be followed up at ages 12 and possibly 24 and 48 months, with questionnaires relating to eating behaviour and feeding practices, food variety and diet quality. Providing guidance and counseling to parents of infants is an important task for health authorities and the public child health services. Early Food for Future health is an intervention focusing on promoting early healthy food-habits which may prevent childhood overweight and obesity. If proven to be effective, Early Food for Future Health can be used by parents and public health nurses for supplementary guidance on feeding practices and diet. This study has the potential to provide greater insight and understanding regarding early parental feeding practices, child eating behavior and the development and efficacy of Internet-based public health interventions. ISRCTN13601567 .

  9. A qualitative study of community perception and acceptance of biological larviciding for malaria mosquito control in rural Burkina Faso.

    PubMed

    Dambach, Peter; Jorge, Margarida Mendes; Traoré, Issouf; Phalkey, Revati; Sawadogo, Hélène; Zabré, Pascal; Kagoné, Moubassira; Sié, Ali; Sauerborn, Rainer; Becker, Norbert; Beiersmann, Claudia

    2018-03-23

    Vector and malaria parasite's rising resistance against pyrethroid-impregnated bed nets and antimalarial drugs highlight the need for additional control measures. Larviciding against malaria vectors is experiencing a renaissance with the availability of environmentally friendly and target species-specific larvicides. In this study, we analyse the perception and acceptability of spraying surface water collections with the biological larvicide Bacillus thuringiensis israelensis in a single health district in Burkina Faso. A total of 12 focus group discussions and 12 key informant interviews were performed in 10 rural villages provided with coverage of various larvicide treatments (all breeding sites treated, the most productive breeding sites treated, and untreated control). Respondents' knowledge about the major risk factors for malaria transmission was generally good. Most interviewees stated they performed personal protective measures against vector mosquitoes including the use of bed nets and sometimes mosquito coils and traditional repellents. The acceptance of larviciding in and around the villages was high and the majority of respondents reported a relief in mosquito nuisance and malarial episodes. There was high interest in the project and demand for future continuation. This study showed that larviciding interventions received positive resonance from the population. People showed a willingness to be involved and financially support the program. The positive environment with high acceptance for larviciding programs would facilitate routine implementation. An essential factor for the future success of such programs would be inclusion in regional or national malaria control guidelines.

  10. Structure-based feeding strategies: A key component of child nutrition.

    PubMed

    Taylor, Maija B; Emley, Elizabeth; Pratt, Mercedes; Musher-Eizenman, Dara R

    2017-07-01

    This study examined the relationship between structure, autonomy promotion, and control feeding strategies and parent-reported child diet. Participants (N = 497) were parents of children ages 2.5 to 7.5 recruited from Amazon Mechanical Turk. This sample was a Caucasian (79%), educated sample (61% college graduates) with most reports from mothers (76%). Online survey including measures of parent feeding strategies and child dietary intake. Use of structure-based feeding strategies explained 21% of the variance in child consumption of added sugar, 12% of the variance in child intake of added sugar from sugar-sweetened beverages, and 16% of the variance in child consumption of fruits and vegetables. Higher unhealthy food availability and permissive feeding uniquely predicted higher child added sugar intake and child consumption of added sugar from sugar-sweetened beverages. Greater healthy food availability uniquely predicted higher child fruit and vegetable intake. and Future Directions: In Caucasian educated families, structure-based feeding strategies appear to be a relatively stronger correlate of parent-reported child intake of added sugar and fruits and vegetables as compared to autonomy promotion and control feeding strategies. Longitudinal research may be needed in order to reveal the relationships between autonomy promotion and control feeding strategies with child diet. If future studies have similar findings to this study's results, researchers may want to focus more heavily on investigating the impact of teaching parents stimulus-control techniques and feeding-related assertiveness skills on child dietary intake. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Role of resilient personality on lower achieving first grade students' current and future achievement

    PubMed Central

    Kwok, Oi-man; Hughes, Jan N.; Luo, Wen

    2007-01-01

    This study investigated a measurement model of personality resilience and the contribution of personality resilience to lower achieving first grade students' academic achievement. Participants were 445 ethnically diverse children who at entrance to first grade scored below their school district median on a test of literacy. Participants were administered an individual achievement test in first grade and 1 year later. Confirmatory factor analysis confirmed a second-order latent construct of resilient personality defined by teacher-rated conscientiousness, agreeableness, and ego-resiliency that was distinct from measures of externalizing behaviors and IQ. Using latent structural equation modeling and controlling for baseline economic adversity, IQ, and externalizing symptoms, resilient personality predicted children's concurrent and future achievement (controlling also for baseline achievement in the prospective analyses). Model fit was invariant across gender. PMID:18084626

  12. Issues for Future Nuclear Arms Control

    NASA Astrophysics Data System (ADS)

    Davis, Jay

    2011-04-01

    Ratification of the New START treaty may open the door to a path of progressive negotiations that could lead to systematic reduction of the numbers of deployed and reserve nuclear weapons. Those negotiations will require more than merely resolving technical, operational and policy questions. Their success will also demand adding successively larger numbers of partners and the building of trust among parties who have not been involved in such agreements before. At some point, questions of conventional arms limitations and larger confidence building steps will inevitably arise. Jay Davis, who last year chaired an APS/POPA study of technology issues for future nuclear arms control agreements, will outline the path, opportunities, and obstacles that lie ahead. Davis was an UNSCOM inspector in Iraq after the First Gulf War and the first director of the Defense Threat Reduction Agency.

  13. Space Weather Effects on Aircraft Navigation

    NASA Astrophysics Data System (ADS)

    Stanley, J. C.; Cade, W. B.

    2012-12-01

    Many aircraft today use satellites for GPS navigation, arrival and departure to and from airspaces, and for "shooting" non-precision and precision Instrument Approaches into airports. Also in development is an Air Traffic Control system based on satellite technology that seeks to modernize current air traffic control and improve safety, eventually phasing out radar (though not yet in the very near future). Due to the general, commercial, and military aviation fields all becoming more and more reliant on satellite and GPS technologies, the effects of space weather events on these systems is of paramount concern to militaries, airlines, private pilots, and other aviation operators. In this study we analyze data from airlines and other resources regarding effects on satellite and GPS systems, which is crucial to the conduct of safe flight operations now and improving systems for future and continued use.

  14. A spacecraft integrated power/attitude control system

    NASA Technical Reports Server (NTRS)

    Keckler, C. R.; Jacobs, K. L.

    1974-01-01

    A study to determine the viability and application of a system capable of performing the dual function of power storage/generation and attitude control has been conducted. Results from the study indicate that an integrated power/attitude control system (IPACS) can satisfy future mission requirements while providing significant savings in weight, volume, and cost over conventional systems. A failure-mode configuration of an IPACS was applied to a shuttle-launched RAM free-flyer and simulated using make-do hardware linked to a hybrid computer. Data from the simulation runs indicate that control interactions resulting from heavy power demands have minimal effect on system control effectiveness. The system was shown to be capable of meeting the stringent pointing requirements of 1 arc-second while operating under the influence of an orbital disturbance environment and during periods of momentum variations imposed by energy transfer requirements.

  15. Workflows and individual differences during visually guided routine tasks in a road traffic management control room.

    PubMed

    Starke, Sandra D; Baber, Chris; Cooke, Neil J; Howes, Andrew

    2017-05-01

    Road traffic control rooms rely on human operators to monitor and interact with information presented on multiple displays. Past studies have found inconsistent use of available visual information sources in such settings across different domains. In this study, we aimed to broaden the understanding of observer behaviour in control rooms by analysing a case study in road traffic control. We conducted a field study in a live road traffic control room where five operators responded to incidents while wearing a mobile eye tracker. Using qualitative and quantitative approaches, we investigated the operators' workflow using ergonomics methods and quantified visual information sampling. We found that individuals showed differing preferences for viewing modalities and weighting of task components, with a strong coupling between eye and head movement. For the quantitative analysis of the eye tracking data, we propose a number of metrics which may prove useful to compare visual sampling behaviour across domains in future. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. Space Station Freedom ECLSS: A step toward autonomous regenerative life support systems

    NASA Technical Reports Server (NTRS)

    Dewberry, Brandon S.

    1990-01-01

    The Environmental Control and Life Support System (ECLSS) is a Freedom Station distributed system with inherent applicability to extensive automation primarily due to its comparatively long control system latencies. These allow longer contemplation times in which to form a more intelligent control strategy and to prevent and diagnose faults. The regenerative nature of the Space Station Freedom ECLSS will contribute closed loop complexities never before encountered in life support systems. A study to determine ECLSS automation approaches has been completed. The ECLSS baseline software and system processes could be augmented with more advanced fault management and regenerative control systems for a more autonomous evolutionary system, as well as serving as a firm foundation for future regenerative life support systems. Emerging advanced software technology and tools can be successfully applied to fault management, but a fully automated life support system will require research and development of regenerative control systems and models. The baseline Environmental Control and Life Support System utilizes ground tests in development of batch chemical and microbial control processes. Long duration regenerative life support systems will require more active chemical and microbial feedback control systems which, in turn, will require advancements in regenerative life support models and tools. These models can be verified using ground and on orbit life support test and operational data, and used in the engineering analysis of proposed intelligent instrumentation feedback and flexible process control technologies for future autonomous regenerative life support systems, including the evolutionary Space Station Freedom ECLSS.

  17. Prospect for future South-Korea arms control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Y.

    1992-04-22

    This study deals with the Hot issues of the first five Prime Ministers (PM) meetings, which encompassed 15 months of negotiations and have resulted in the completion of the Agreement on South-North Reconciliation/Non-aggression and Cooperation after 46 years of division. After the signing of the agreement, detailed worker level progress has culminated in North Korea signing the nuclear safety treaty of the International Atomic Energy Agency (IAEA) and Acceptance of International Inspection of Nuclear Facilities South-North civil economic progress is on the way and at the 6th meeting, a head of state meeting was discussed. Taking all this into consideration,more » it is safe to say that an affirmative direction is being taken towards South-North relations. In this arena, a critical element for better South-North relations is arms control. If meetings on arms control between South-North make good progress, the solution for the Korean peninsula's reunification, as well as detente, will be achieved more quickly. Therefore, arms control on the Korean peninsula should be considered as an important point for improvement of the future South-North Korean relationship. The important fact that we should remember is that arms control is a common issue. Arms control should be solved by South-North Korea because a phased arms control can develop prior to conditions for reunification.« less

  18. Helicopter aeroelastic stability and response - Current topics and future trends

    NASA Technical Reports Server (NTRS)

    Friedmann, Peretz P.

    1990-01-01

    This paper presents several current topics in rotary wing aeroelasticity and concludes by attempting to anticipate future trends and developments. These topics are: (1) the role of geometric nonlinearities; (2) structural modeling, and aeroelastic analysis of composite rotor blades; (3) aeroelastic stability and response in forward flight; (4) modeling of coupled rotor/fuselage aeromechanical problems and their active control; and (5) the coupled rotor-fuselage vibration problem and its alleviation by higher harmonic control. Selected results illustrating the fundamental aspects of these topics are presented. Future developments are briefly discussed.

  19. Economics of infection control surveillance technology: cost-effective or just cost?

    PubMed

    Furuno, Jon P; Schweizer, Marin L; McGregor, Jessina C; Perencevich, Eli N

    2008-04-01

    Previous studies have suggested that informatics tools, such as automated alert and decision support systems, may increase the efficiency and quality of infection control surveillance. However, little is known about the cost-effectiveness of these tools. We focus on 2 types of economic analyses that have utility in assessing infection control interventions (cost-effectiveness analysis and business-case analysis) and review the available literature on the economics of computerized infection control surveillance systems. Previous studies on the effectiveness of computerized infection control surveillance have been limited to assessments of whether these tools increase the sensitivity and specificity of surveillance over traditional methods. Furthermore, we identified only 2 studies that assessed the costs associated with computerized infection control surveillance. Thus, it remains unknown whether computerized infection control surveillance systems are cost-effective and whether use of these systems improves patient outcomes. The existing data are insufficient to allow for a summary conclusion on the cost-effectiveness of infection control surveillance technology. All future studies of computerized infection control surveillance systems should aim to collect outcomes and economic data to inform decision making and assist hospitals with completing business-cases analyses.

  20. Accounting for control mislabeling in case-control biomarker studies.

    PubMed

    Rantalainen, Mattias; Holmes, Chris C

    2011-12-02

    In biomarker discovery studies, uncertainty associated with case and control labels is often overlooked. By omitting to take into account label uncertainty, model parameters and the predictive risk can become biased, sometimes severely. The most common situation is when the control set contains an unknown number of undiagnosed, or future, cases. This has a marked impact in situations where the model needs to be well-calibrated, e.g., when the prediction performance of a biomarker panel is evaluated. Failing to account for class label uncertainty may lead to underestimation of classification performance and bias in parameter estimates. This can further impact on meta-analysis for combining evidence from multiple studies. Using a simulation study, we outline how conventional statistical models can be modified to address class label uncertainty leading to well-calibrated prediction performance estimates and reduced bias in meta-analysis. We focus on the problem of mislabeled control subjects in case-control studies, i.e., when some of the control subjects are undiagnosed cases, although the procedures we report are generic. The uncertainty in control status is a particular situation common in biomarker discovery studies in the context of genomic and molecular epidemiology, where control subjects are commonly sampled from the general population with an established expected disease incidence rate.

  1. Future prospects for space life sciences from a NASA perspective

    NASA Technical Reports Server (NTRS)

    White, Ronald J.; Lujan, Barbara F.

    1989-01-01

    Plans for future NASA research programs in the life sciences are reviewed. Consideration is given to international cooperation in space life science research, the NASA approach to funding life science research, and research opportunities using the Space Shuttle, the Space Station, and Biological Satellites. Several specific programs are described, including the Centrifuge Project to provide a controlled acceleration environment for microgravity studies, the Rhesus Project to conduct biomedical research using rhesus monkeys, and the LifeSat international biosatellite project. Also, the Space Biology Initiative to design and develop life sciences laboratory facilities for the Space Shuttle and the Space Station and the Extended Duration Crew Operations program to study crew adaptation needs are discussed.

  2. Imagining the Future in Children with Severe Traumatic Brain Injury.

    PubMed

    Lah, Suncica; Gott, Chloe; Epps, Adrienne; Parry, Louise

    2018-06-12

    Imagining future events is thought to rely on recombination and integration of past episodic memory traces into future events. Future and past events contain episodic and nonepisodic details. Children with severe traumatic brain injury (TBI) were found to have impaired recall of past episodic (but not semantic) event details. Here, we examined whether severe TBI impairs construction of future events. Children with severe TBI (n = 15) and healthy controls (NC; n = 33) 1) completed tests of anterograde (narrative and relational) memory and executive skills, 2) recalled past events and generated future events, and 3) rated events' phenomenological qualities. Events were scored for episodic (internal) and semantic (external) details. The groups did not differ in generating details of future events, although children with TBI recalled significantly fewer past internal (but not external) events' details relative to NCs. Moreover, the number of past internal details relative to future internal details was significantly higher in the NC group, but not in the TBI groups. Significant correlations between past and future were found for 1) internal details in both groups and 2) external details in the NC group. The TBI group rated their events as being less significant than did the NC group. The groups did not differ on ratings of visual intensity and rehearsal. Our study has shown that children who have sustained severe TBI had impoverished recall of past, but not generation of future, events. This unexpected dissociation between past and future event construction requires further research.

  3. Post Cold War Nuclear Weapons Policy

    DTIC Science & Technology

    2012-03-20

    are unknown.”14 This instability threatens the success and future of the NPT. According to scholar Joseph F. Pilat , While the vision of a nuclear...for the Study of Weapons of Mass Destruction, April 2007. 15 Joseph F. Pilat , “Nonproliferation, Arms Control and Disarmament, and ExtendedDeterrence

  4. Counteracting Obstacles with Optimistic Predictions

    ERIC Educational Resources Information Center

    Zhang, Ying; Fishbach, Ayelet

    2010-01-01

    This research tested for counteractive optimism: a self-control strategy of generating optimistic predictions of future goal attainment in order to overcome anticipated obstacles in goal pursuit. In support of the counteractive optimism model, participants in 5 studies predicted better performance, more time invested in goal activities, and lower…

  5. Policies and Programs for Prevention and Control of Diabetes in Iran: A Document Analysis.

    PubMed

    Faraji, Obeidollah; Etemad, Koorosh; Akbari Sari, Ali; Ravaghi, Hamid

    2015-04-19

    Trend analysis in 2005 to 2011 showed high growth in diabetes prevalence in Iran. Considering the high prevalence of diabetes in the country and likely to increase its prevalence in the future, the analysis of diabetes-related policies and programs is very important and effective in the prevention and control of diabetes. Therefore, the aim of the study was an analysis of policies and programs related to prevention and control of diabetes in Iran in 2014. This study was a policy analysis using deductive thematic content analysis of key documents. The health policy triangle framework was used in the data analysis. PubMed and ScienceDirect databases were searched to find relevant studies and documents. Also, hand searching was conducted among references of the identified studies. MAXQDA 10 software was used to organize and analyze data. The main reasons to take into consideration diabetes in Iran can be World Health Organization (WHO) report in 1989, and high prevalence of diabetes in the country. The major challenges in implementing the diabetes program include difficulty in referral levels of the program, lack of coordination between the private sector and the public sector and the limitations of reporting system in the specialized levels of the program. Besides strengthening referral system, the government should allocate more funds to the program and more importance to the educational programs for the public. Also, Non-Governmental Organizations (NGOs) and the private sector should involve in the formulation and implementation of the prevention and control programs of diabetes in the future.

  6. Medial Temporal Lobe Damage Causes Deficits in Episodic Memory and Episodic Future Thinking Not Attributable to Deficits in Narrative Construction

    PubMed Central

    Race, Elizabeth; Keane, Margaret M.; Verfaellie, Mieke

    2015-01-01

    The medial temporal lobe (MTL) makes critical contributions to episodic memory, but its contributions to episodic future thinking remain a matter of debate. By one view, imagining future events relies on MTL mechanisms that also support memory for past events. Alternatively, it has recently been suggested that future thinking is independent of MTL-mediated processes and can be supported by regions outside the MTL. The current study investigated the nature and necessity of MTL involvement in imagining the future and tested the novel hypothesis that the MTL contributes to future thinking by supporting online binding processes related to narrative construction. Human amnesic patients with well-characterized MTL damage and healthy controls constructed narratives about (a) future events, (b) past events, and (c) visually-presented pictures. While all three tasks place similar demands on narrative construction, only the past and future conditions require memory/future thinking to mentally generate relevant narrative information. Patients produced impoverished descriptions of both past and future events but were unimpaired at producing detailed picture narratives. In addition, future-thinking performance positively correlated with episodic memory performance but did not correlate with picture narrative performance. Finally, future-thinking impairments were present when MTL lesions were restricted to the hippocampus and did not depend on the presence of neural damage outside the MTL. These results indicate that the ability to generate and maintain a detailed narrative is preserved in amnesia and suggest that a common MTL mechanism supports both episodic memory and episodic future thinking. PMID:21753003

  7. Medial temporal lobe damage causes deficits in episodic memory and episodic future thinking not attributable to deficits in narrative construction.

    PubMed

    Race, Elizabeth; Keane, Margaret M; Verfaellie, Mieke

    2011-07-13

    The medial temporal lobe (MTL) makes critical contributions to episodic memory, but its contributions to episodic future thinking remain a matter of debate. By one view, imagining future events relies on MTL mechanisms that also support memory for past events. Alternatively, it has recently been suggested that future thinking is independent of MTL-mediated processes and can be supported by regions outside the MTL. The current study investigated the nature and necessity of MTL involvement in imagining the future and tested the novel hypothesis that the MTL contributes to future thinking by supporting online binding processes related to narrative construction. Human amnesic patients with well characterized MTL damage and healthy controls constructed narratives about (1) future events, (2) past events, and (3) visually presented pictures. While all three tasks place similar demands on narrative construction, only the past and future conditions require memory/future thinking to mentally generate relevant narrative information. Patients produced impoverished descriptions of both past and future events but were unimpaired at producing detailed picture narratives. In addition, future-thinking performance positively correlated with episodic memory performance but did not correlate with picture narrative performance. Finally, future-thinking impairments were present when MTL lesions were restricted to the hippocampus and did not depend on the presence of neural damage outside the MTL. These results indicate that the ability to generate and maintain a detailed narrative is preserved in amnesia and suggest that a common MTL mechanism supports both episodic memory and episodic future thinking.

  8. A Tale of Smoking Cessation Promotion: The Utilization of a Children's Book to Increase Screening and Counseling in the Pediatric Clinic.

    PubMed

    Thomas, Katharine E H; Kisely, Steve; Urrego, Fernando

    2017-10-01

    The rate at which pediatricians promote smoking cessation in clinical settings is low. The literature demonstrates that interventions paired with tangible health promotion materials may significantly increase screening rates to the pediatric office. The aim of this study was to investigate whether the addition of a children's book in the pediatric clinic could result in an increase in the rate in which pediatricians screened for secondhand smoke exposure (SHSe) and counseled caregivers to stop smoking. This randomized controlled study was performed at 7 pediatric clinics. Seven pediatric clinic sites were randomly assigned to either an intervention or control group. Pediatricians in the intervention group were given children's books about SHSe to distribute to their patients while the control group did not receive any materials. At baseline, there was no difference between the control group and intervention group in rates at which pediatricians screened for SHSe ( P = .8728) and counseled caregivers to stop smoking ( P = .29). After the intervention, screening for SHSe and counseling caregivers to stop smoking were statistically significantly greater in the intervention group, when compared to controls ( P < .01 and P < .001, respectively). The use of a health promotion children's book in the pediatric setting can increase the rate at which pediatricians screen for SHSe and counsel caregivers to stop smoking. Future research should examine the effect of the storybook on various parameters of smoking cessation and future smoking behaviors.

  9. Anxiety Disorders are Associated with Reduced Heart Rate Variability: A Meta-Analysis

    PubMed Central

    Chalmers, John A.; Quintana, Daniel S.; Abbott, Maree J.-Anne; Kemp, Andrew H.

    2014-01-01

    Background: Anxiety disorders increase risk of future cardiovascular disease (CVD) and mortality, even after controlling for confounds including smoking, lifestyle, and socioeconomic status, and irrespective of a history of medical disorders. While impaired vagal function, indicated by reductions in heart rate variability (HRV), may be one mechanism linking anxiety disorders to CVD, prior studies have reported inconsistent findings highlighting the need for meta-analysis. Method: Studies comparing resting-state HRV recordings in patients with an anxiety disorder as a primary diagnosis and healthy controls were considered for meta-analysis. Results: Meta-analyses were based on 36 articles, including 2086 patients with an anxiety disorder and 2294 controls. Overall, anxiety disorders were characterized by lower HRV [high frequency (HF): Hedges’ g = −0.29. 95% CI: −0.41 to −0.17, p < 0.001; time domain: Hedges’ g = −0.45, 95% CI: −0.57 to −0.33, p < 0.001] than controls. Panic disorder (n = 447), post-traumatic stress disorder (n = 192), generalized anxiety disorder (n = 68), and social anxiety disorder (n = 90), but not obsessive–compulsive disorder (n = 40), displayed reductions in HF HRV relative to controls (all ps < 0.001). Conclusion: Anxiety disorders are associated with reduced HRV, findings associated with a small-to-moderate effect size. Findings have important implications for future physical health and well-being of patients, highlighting a need for comprehensive cardiovascular risk reduction. PMID:25071612

  10. Prediction of future risk of insulin resistance and metabolic syndrome based on Korean boy's metabolite profiling.

    PubMed

    Lee, AeJin; Jang, Han Byul; Ra, Moonjin; Choi, Youngshim; Lee, Hye-Ja; Park, Ju Yeon; Kang, Jae Heon; Park, Kyung-Hee; Park, Sang Ick; Song, Jihyun

    2015-01-01

    Childhood obesity is strongly related to future insulin resistance and metabolic syndrome. Thus, identifying early biomarkers of obesity-related diseases based on metabolic profiling is useful to control future metabolic disorders. We compared metabolic profiles between obese and normal-weight children and investigated specific biomarkers of future insulin resistance and metabolic syndrome. In all, 186 plasma metabolites were analysed at baseline and after 2 years in 109 Korean boys (age 10.5±0.4 years) from the Korean Child Obesity Cohort Study using the AbsoluteIDQ™ p180 Kit. We observed that levels of 41 metabolites at baseline and 40 metabolites at follow-up were significantly altered in obese children (p<0.05). Obese children showed significantly higher levels of branched-chain amino acids (BCAAs) and several acylcarnitines and lower levels of acyl-alkyl phosphatidylcholines. Also, baseline BCAAs were significantly positively correlated with both homeostasis model assessment for insulin resistance (HOMA-IR) and continuous metabolic risk score at the 2-year follow-up. In logistic regression analyses with adjustments for degree of obesity at baseline, baseline BCAA concentration, greater than the median value, was identified as a predictor of future risk of insulin resistance and metabolic syndrome. High BCAA concentration could be "early" biomarkers for predicting future metabolic diseases. Copyright © 2014 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.

  11. Adaptation of a modern medium helicopter (Sikorsky S-76) to higher harmonic control

    NASA Technical Reports Server (NTRS)

    Oleary, J. J.; Kottapalli, S. B. R.; Davis, M. W.

    1985-01-01

    Sikorsky Aircraft has performed analytical studies, design analyses, and risk reduction tests have been performed for Higher Harmonic Control (HHC) on the S-76. The S-76 is an 8 to 10,000 lb helicopter which cruises at 145 kts. Flight test hardware has been assembled, main servo frequency response tested and upgraded, aircraft control system shake tested and verified, open loop controllers designed and fabricated, closed loop controllers defined and evaluated, and rotors turning ground and flight tests planned for the near future. Open loop analysis shows that about 2 deg of higher harmonic feathering at the blade 75% radius will be required to eliminate 4P vibration in the cockpit.

  12. How Schools Can Control the Increasing Cost of Energy.

    ERIC Educational Resources Information Center

    Levy, Hans F.

    In a nontechnical way, this small book outlines the present use of energy in schools, what forms of energy will be available in the foreseeable future, how energy is presently wasted in educational facilities, and how energy can be conserved now and in the future. The school administrator can control the energy consumption in his schools and this…

  13. Integrating nuclear weapons stockpile management and nuclear arms control to enable significant stockpile reductions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sanders, Lani Miyoshi; DeLand, Sharon M.; Pregenzer, Arian L.

    2010-11-01

    In his 2009 Prague speech and the 2010 Nuclear Posture Review, President Barack Obama committed the United States to take concrete steps toward nuclear disarmament while maintaining a safe, secure, and effective nuclear deterrent. There is an inherent tension between these two goals that is best addressed through improved integration of nuclear weapons objectives with nuclear arms control objectives. This article reviews historical examples of the interaction between the two sets of objectives, develops a framework for analyzing opportunities for future integration, and suggests specific ideas that could benefit the nuclear weapons enterprise as it undergoes transformation and that couldmore » make the future enterprise compatible with a variety of arms control futures.« less

  14. Design of clinical trials of antidepressants: should a placebo control arm be included?

    PubMed

    Fritze, J; Möller, H J

    2001-01-01

    There is no doubt that available antidepressants are efficacious and effective. Nevertheless, more effective drugs with improved tolerability are needed. With this need in mind, some protagonists claim that future antidepressants should be proved superior to, or at least as effective as, established antidepressants, making placebo control methodologically dispensable in clinical trials. Moreover, the use of placebo control is criticised as unethical because it might result in effective treatment being withheld. There are, however, a number of methodological reasons why placebo control is indispensable for the proof of efficacy of antidepressants. Comparing investigational antidepressants only with standard antidepressants and not placebo yields ambiguous results that are difficult to interpret, be it in superiority or equivalence testing, and this method of assessment requires larger sample sizes than those required with the use of placebo control. Experimental methodology not adhering to the optimal study design is ethically questionable. Restricting the testing of investigational antidepressants only to superiority over standard antidepressants is an obstacle to therapeutic progress in terms of tolerability and the detection of innovative mechanisms of action from which certain subgroups of future patients might benefit. The use of a methodology that requires larger samples for testing of superiority or equivalence is also ethically questionable. In view of the high placebo response rates in trials of antidepressants, placebo treatment does not mean withholding effective treatment. Accepting the necessity of the clinical evaluation of new, potentially ineffective antidepressants implicitly means accepting placebo control as ethically justified. Three- or multi-arm comparisons including placebo and an active reference represent the optimal study design.

  15. Testing an alternate informed consent process.

    PubMed

    Yates, Bernice C; Dodendorf, Diane; Lane, Judy; LaFramboise, Louise; Pozehl, Bunny; Duncan, Kathleen; Knodel, Kendra

    2009-01-01

    One of the main problems in conducting clinical trials is low participation rate due to potential participants' misunderstanding of the rationale for the clinical trial or perceptions of loss of control over treatment decisions. The objective of this study was to test an alternate informed consent process in cardiac rehabilitation participants that involved the use of a multimedia flip chart to describe a future randomized clinical trial and then asked, hypothetically, if they would participate in the future trial. An attractive and inviting visual presentation of the study was created in the form of a 23-page flip chart that included 24 color photographs displaying information about the purpose of the study, similarities and differences between the two treatment groups, and the data collection process. We tested the flip chart in 35 cardiac rehabilitation participants. Participants were asked if they would participate in this future study on two occasions: immediately after the description of the flip chart and 24 hours later, after reading through the informed consent document. Participants were also asked their perceptions of the flip chart and consent process. Of the 35 participants surveyed, 19 (54%) indicated that they would participate in the future study. No participant changed his or her decision 24 hours later after reading the full consent form. The participation rate improved 145% over that of an earlier feasibility study where the recruitment rate was 22%. Most participants stated that the flip chart was helpful and informative and that the photographs were effective in communicating the purpose of the study. Participation rates could be enhanced in future clinical trials by using a visual presentation to explain and describe the study as part of the informed consent process. More research is needed to test alternate methods of obtaining informed consent.

  16. Can paramedics use FRAX (the WHO Fracture Risk Assessment Tool) to help GPs improve future fracture risk in patients who fall? Protocol for a randomised controlled feasibility study.

    PubMed

    Clarke, Shane; Bradley, Rachel; Simmonds, Bethany; Salisbury, Chris; Benger, Jonathan; Marques, Elsa; Greenwood, Rosemary; Shepstone, Lee; Robinson, Maria; Appleby-Fleming, John; Gooberman-Hill, Rachael

    2014-09-03

    Currently identification, and therefore, management of patients at risk of osteoporotic fracture in the UK is suboptimal. As the majority of patients who fracture have fallen, it follows that people who fall can usefully be targeted in any programme that aims to reduce osteoporotic fracture. Targeting vulnerable patients who are likely to benefit from intervention may help shift the management of fracture prevention into primary care, away from emergency departments. Paramedics who attend to patients who have fallen may be well placed to assess future fracture risk, using the Fracture Risk Assessment Tool (FRAX) and communicate that information directly to general practitioners (GPs). This feasibility study takes the form of a pragmatic, randomised controlled trial aimed at exploring and refining issues of study design, recruitment, retention, sample size and acceptability preceding a large-scale study with fracture as the end point. Patients (aged >50) who fall, call an ambulance, are attended by a study paramedic and give verbal consent will be asked FRAX and fall questions. Patients who subsequently formally consent to participation will be randomised to control (usual care) or intervention groups. Intervention will constitute transmission of calculated future fracture risk to the patients' GP with suitable, evidence-based recommendations for investigation or treatment. 3 months after the index fall, data (proportion of patients in each group undergoing investigation or starting new treatment, quality of life and health economic) will be collected and analysed using descriptive statistics. A nested qualitative study will explore issues of acceptability and study design with patients, paramedics and GPs. This protocol was approved by NRES Committee South Central Oxford C in October 2012. Research Ethics Committee ref.12/SC/0604. The study findings will be disseminated through peer-reviewed journals, conference presentations and local public events. A publication plan and authorship criteria have been preagreed. 36245726. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  17. Predictive control of hollow-fiber bioreactors for the production of monoclonal antibodies.

    PubMed

    Dowd, J E; Weber, I; Rodriguez, B; Piret, J M; Kwok, K E

    1999-05-20

    The selection of medium feed rates for perfusion bioreactors represents a challenge for process optimization, particularly in bioreactors that are sampled infrequently. When the present and immediate future of a bioprocess can be adequately described, predictive control can minimize deviations from set points in a manner that can maximize process consistency. Predictive control of perfusion hollow-fiber bioreactors was investigated in a series of hybridoma cell cultures that compared operator control to computer estimation of feed rates. Adaptive software routines were developed to estimate the current and predict the future glucose uptake and lactate production of the bioprocess at each sampling interval. The current and future glucose uptake rates were used to select the perfusion feed rate in a designed response to deviations from the set point values. The routines presented a graphical user interface through which the operator was able to view the up-to-date culture performance and assess the model description of the immediate future culture performance. In addition, fewer samples were taken in the computer-estimated cultures, reducing labor and analytical expense. The use of these predictive controller routines and the graphical user interface decreased the glucose and lactate concentration variances up to sevenfold, and antibody yields increased by 10% to 43%. Copyright 1999 John Wiley & Sons, Inc.

  18. Psycho-educational strategies to promote fluid adherence in adult hemodialysis patients: a review of intervention studies.

    PubMed

    Welch, Janet L; Thomas-Hawkins, Charlotte

    2005-07-01

    We reviewed psycho-educational intervention studies that were designed to reduce interdialytic weight gain (IDWG) in adult hemodialysis patients. Our goals were to critique research methods, describe the effectiveness of tested interventions, and make recommendations for future research. Medline, PsychInfo, and the Cumulative Index to Nursing and Applied Health (CINAHL) databases were searched to identify empirical work. Each study was evaluated in terms of sample, design, theoretical framework, intervention delivery, and outcome. Nine studies were reviewed. Self-monitoring appears to be a promising strategy to be considered to reduce IDWG. Theory was not usually used to guide interventions, designs generally had control groups, interventions were delivered individually, more than one intervention was delivered at a time, the duration of the intervention varied greatly, there was no long-term follow-up, IDWG was the only outcome, and IDWG was operationalized in different ways. Theoretical models and methodological rigor are needed to guide future research. Specific recommendations on design, measurement, and conceptual issues are offered to enhance the effectiveness of future research.

  19. Large space structures controls research and development at Marshall Space Flight Center: Status and future plans

    NASA Technical Reports Server (NTRS)

    Buchanan, H. J.

    1983-01-01

    Work performed in Large Space Structures Controls research and development program at Marshall Space Flight Center is described. Studies to develop a multilevel control approach which supports a modular or building block approach to the buildup of space platforms are discussed. A concept has been developed and tested in three-axis computer simulation utilizing a five-body model of a basic space platform module. Analytical efforts have continued to focus on extension of the basic theory and subsequent application. Consideration is also given to specifications to evaluate several algorithms for controlling the shape of Large Space Structures.

  20. Active vibration control activities at the LaRC - Present and future

    NASA Technical Reports Server (NTRS)

    Newsom, J. R.

    1990-01-01

    The NASA Controls-Structures-Interaction (CSI) program is presented with a description of the ground testing element objectives and approach. The goal of the CSI program is to develop and validate the technology required to design, verify and operate space systems in which the structure and the controls interact beneficially to meet the needs of future NASA missions. The operational Mini-Mast ground testbed and some sample active vibration control experimental results are discussed along with a description of the CSI Evolutionary Model testbed presently under development. Initial results indicate that embedded sensors and actuators are effective in controlling a large truss/reflector structure.

  1. Job design and job stress in office workers.

    PubMed

    Carayon, P

    1993-05-01

    A model to look at various job components that affect individual well-being and health was developed drawing from the job design and job stress literature. Briefly stated, the model proposes job control to be a primary causal determinant of the stress outcomes. The effects of perceived demands, job content, and career/future concerns were hypothesized to influence the stress outcomes only to the extent of their influence on job control. This was tested in a population of government office employees in various clerical, professional, and managerial jobs all of which involve the use of computers. Results indicated that job control was not a crucial determinant of the stress outcomes, that job demands and career/future concerns were consistent determinants of the stress outcomes, and that job content, demands, and career/future concerns did not influence the stress outcomes through job control as described by the proposed model. The differentiation of job control levels to define specific relationships with stress outcomes and other job elements was shown to be useful because different levels of job control were associated with different stress outcomes and job elements.

  2. Design of a symmetry controller for cycling induced by electrical stimulation: preliminary results on post-acute stroke patients.

    PubMed

    Ambrosini, Emilia; Ferrante, Simona; Schauer, Thomas; Ferrigno, Giancarlo; Molteni, Franco; Pedrocchi, Alessandra

    2010-08-01

    This study deals with the design of a controller for cycling induced by functional electrical stimulation. The controller will be exploitable in the rehabilitation of hemiparetic patients who need to recover motor symmetry. It uses the pulse width as the control variable in the stimulation of the two legs in order to nullify the unbalance between the torques produced at the two crank arms. It was validated by means of isokinetic trials performed both by healthy subjects and stroke patients. The results showed that the controller was able to reach, and then maintain, a symmetrical pedaling. In the future, the controller will be validated on a larger number of stroke patients.

  3. An aeroelastician's perspective of wind tunnel and flight experiences with active control of structural response and stability

    NASA Technical Reports Server (NTRS)

    Hanson, P. W.

    1984-01-01

    Active controls technology is assessed based on a review of most of the wind-tunnel and flight tests and actual applications of active control concepts since the late sixties. The distinction is made between so-called ""rigid-body'' active control functions and those that involve significant modification of structural elastic response or stability. Both areas are reviewed although the focus is on the latter area. The basic goals and major results of the various studies or applications are summarized, and the anticipated use of active controls on current and near-future research and demonstration aircraft is discussed. Some of the ""holes'' remaining in the feasbility/benefits demonstration of active controls technology are examined.

  4. Audiological Rehabilitation for Facilitating Hearing Aid Use: A Review.

    PubMed

    Aazh, Hashir; Moore, Brian C J

    2017-03-01

    This article reviews and critically analyzes the design of studies on the effect of audiological rehabilitation (AR) programs on hearing aid (HA) outcomes, in order to guide future research. The design of this study was a narrative review. Studies were included in the review if they were randomized controlled trials that investigated the effects of AR on HA use and outcome between 2000 and 2016. Seven articles that met the inclusion criteria were included in the review. Most used educational rather than counseling approaches. Although educational AR programs seem to be useful in enhancing the use of communication strategies, there is limited evidence for their effect on HA use and self-perceived hearing handicap. More research is needed in this field. Future studies should (1) investigate the efficacy of AR interventions based on counseling and empathetic listening as opposed to or in addition to educational interventions, (2) use stricter criteria to include only a subpopulation of patients who do not get on well with their HAs, (3) measure the amount of HA use via data-logging and self-report questionnaires, and (4) use a matching comparison intervention for patients in the control group. American Academy of Audiology

  5. Pressure control and analysis report: Hydrogen Thermal Test Article (HTTA)

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Tasks accomplished during the HTTA Program study period included: (1) performance of a literature review to provide system guidelines; (2) development of analytical procedures needed to predict system performance; (3) design and analysis of the HTTA pressurization system considering (a) future utilization of results in the design of a spacecraft maneuvering system propellant package, (b) ease of control and operation, (c) system safety, and (d) hardware cost; and (4) making conclusions and recommendations for systems design.

  6. Recalling Experiences of Teen Dating Violence: An Examination of Its Relationship to Family Violence and Locus of Control amongst African Americans and How These Variables Impact Relationships in Adulthood

    ERIC Educational Resources Information Center

    McCain, Stephanie D.

    2015-01-01

    The purpose of this study was two-fold: 1) to identify the relationship between witnessing violence at home and the effects it has on teen dating violence and future experiences with violence; and 2) to assess how perceived locus of control may reduce or exacerbate the relationship between each of the risk factors and perpetration of dating…

  7. New High: A Future-Oriented Study of American Drug Policy

    DTIC Science & Technology

    2017-12-01

    firearms  Space travel  Quantum computing  Embodied intelligence augmentation  Xenotransplantation  Artificial intelligence  CRISPR  3D printing...498 Office of National Drug Control Policy, National Drug Control Strategy, 32. 499 Amy Webb, “ Crispr Makes It Clear: The U.S...Needs a Biology Strategy, and Fast,” Wired, May 11, 2017, www.wired.com/2017/05/ crispr -makes-clear-US-needs-biology-strategy-fast/. 500 Ibid. 501

  8. Terminal Area Procedures for Paired Runways

    NASA Technical Reports Server (NTRS)

    Lozito, Sandy

    2011-01-01

    Parallel Runway operations have been found to increase capacity within the National Airspace (NAS) however, poor visibility conditions reduce this capacity [1]. Much research has been conducted to examine the concepts and procedures related to parallel runways however, there has been no investigation of the procedures associated with the strategic and tactical pairing of aircraft for these operations. This study developed and examined the pilot and controller procedures and information requirements for creating aircraft pairs for parallel runway operations. The goal was to achieve aircraft pairing with a temporal separation of 15s(+/- 10s error) at a coupling point that is about 12 nmi from the runway threshold. Two variables were explored for the pilot participants: Two levels of flight deck automation (current-day flight deck automation, and a prototype future automation) as well as two flight deck displays that assisted in pilot conformance monitoring. The controllers were also provided with automation to help create and maintain aircraft pairs. Data showed that the operations in this study were found to be acceptable and safe. Workload when using the pairing procedures and tools was generally low for both controllers and pilots, and situation awareness (SA) was typically moderate to high. There were some differences based upon the display and automation conditions for the pilots. Future research should consider the refinement of the concepts and tools for pilot and controller displays and automation for parallel runway concepts.

  9. Advances in clinical NK cell studies: Donor selection, manufacturing and quality control

    PubMed Central

    Koehl, U.; Kalberer, C.; Spanholtz, J.; Lee, D. A.; Miller, J. S.; Cooley, S.; Lowdell, M.; Uharek, L.; Klingemann, H.; Curti, A.; Leung, W.; Alici, E.

    2016-01-01

    ABSTRACT Natural killer (NK) cells are increasingly used in clinical studies in order to treat patients with various malignancies. The following review summarizes platform lectures and 2013–2015 consortium meetings on manufacturing and clinical use of NK cells in Europe and United States. A broad overview of recent pre-clinical and clinical results in NK cell therapies is provided based on unstimulated, cytokine-activated, as well as genetically engineered NK cells using chimeric antigen receptors (CAR). Differences in donor selection, manufacturing and quality control of NK cells for cancer immunotherapies are described and basic recommendations are outlined for harmonization in future NK cell studies. PMID:27141397

  10. Correlates of meal skipping in young adults: a systematic review.

    PubMed

    Pendergast, Felicity J; Livingstone, Katherine M; Worsley, Anthony; McNaughton, Sarah A

    2016-12-01

    Meal skipping rates may be highest during young adulthood, a period of transition and development. Although these dietary behaviours may increase future risk of chronic disease, limited research has investigated correlates of meal skipping in young adults. A systematic literature search was conducted to identify studies that investigated correlates of meal skipping behaviours in young adults (aged 18-30 years). EBSCO host, MEDLINE Complete, Global Health, Scopus, EMBASE, Web of Science and Informit platforms were searched for eligible articles. Correlates were defined as any factor that was either associated with meal skipping or was self-reported by the participant to have an influence on meal skipping. Randomised controlled trials, prospective cohort studies, case-control studies, nested case-control studies, cross-sectional studies, and longitudinal studies were eligible for inclusion. Three-hundred and thirty-one articles were identified, 141 full-text articles assessed for eligibility, resulting in 35 included studies. Multiple methodological and reporting weaknesses were apparent in the reviewed studies with 28 of the 35 studies scoring a negative rating in the risk of bias assessment. Meal skipping (any meal), defined as the skipping of any meal throughout the day, was reported in 12 studies with prevalence ranging between 5 and 83%. The remaining 25 studies identified specific meals and their skipping rates, with breakfast the most frequently skipped meal 14-88% compared to lunch 8-57% and dinner 4-57%. Lack of time was consistently reported as an important correlate of meal skipping, compared with correlates such as cost and weight control, while sex was the most commonly reported associated correlate. Breakfast skipping was more common among men while lunch or dinner skipping being more common among women. This review is the first to examine potential correlates of meal skipping in young adults. Future research would benefit from stronger design and reporting strategies, using a standardised approach for measuring and defining meal skipping.

  11. The Potential of Technology-Based Psychological Interventions for Anorexia and Bulimia Nervosa: A Systematic Review and Recommendations for Future Research

    PubMed Central

    Bürger, Carolina; Schmidt, Luise; Herbst, Nirmal; Voderholzer, Ulrich

    2015-01-01

    Background Previous studies have shown an unmet need in the treatment of eating disorders. In the last decade, interest in technology-based interventions (TBIs) (including computer- and Internet-based interventions [CBIs] or mobile interventions) for providing evidence-based therapies to individuals with different mental disorders has increased. Objective The aim of this review was to systematically evaluate the potential of TBIs in the field of eating disorders, namely for anorexia nervosa (AN) and bulimia nervosa (BN), for both prevention and treatment, and also for carers of eating disorder patients. Methods A systematic literature search was conducted using Medline and PsycINFO. Bibliographies of retrieved articles were also reviewed without date or study type restrictions. Results Forty studies resulting in 45 publications reporting outcomes fulfilled the inclusion criteria: 22 randomized controlled trials, 2 controlled studies, and 16 uncontrolled studies. In total, 3646 patients were included. Overall, the studies provided evidence for the efficacy of guided CBIs, especially for BN patients and for compliant patients. Furthermore, videoconferencing also appeared to be a promising approach. Evaluation results of Internet-based prevention of eating disorders and Internet-based programs for carers of eating disorder patients were also encouraging. Finally, there was preliminary evidence for the efficacy of mobile interventions. Conclusions TBIs may be an additional way of delivering evidence-based treatments to eating disorder patients and their use is likely to increase in the near future. TBIs may also be considered for the prevention of eating disorders and to support carers of eating disorder patients. Areas of future research and important issues such as guidance, therapeutic alliance, and dissemination are discussed. PMID:25840591

  12. The potential of technology-based psychological interventions for anorexia and bulimia nervosa: a systematic review and recommendations for future research.

    PubMed

    Schlegl, Sandra; Bürger, Carolina; Schmidt, Luise; Herbst, Nirmal; Voderholzer, Ulrich

    2015-03-31

    Previous studies have shown an unmet need in the treatment of eating disorders. In the last decade, interest in technology-based interventions (TBIs) (including computer- and Internet-based interventions [CBIs] or mobile interventions) for providing evidence-based therapies to individuals with different mental disorders has increased. The aim of this review was to systematically evaluate the potential of TBIs in the field of eating disorders, namely for anorexia nervosa (AN) and bulimia nervosa (BN), for both prevention and treatment, and also for carers of eating disorder patients. A systematic literature search was conducted using Medline and PsycINFO. Bibliographies of retrieved articles were also reviewed without date or study type restrictions. Forty studies resulting in 45 publications reporting outcomes fulfilled the inclusion criteria: 22 randomized controlled trials, 2 controlled studies, and 16 uncontrolled studies. In total, 3646 patients were included. Overall, the studies provided evidence for the efficacy of guided CBIs, especially for BN patients and for compliant patients. Furthermore, videoconferencing also appeared to be a promising approach. Evaluation results of Internet-based prevention of eating disorders and Internet-based programs for carers of eating disorder patients were also encouraging. Finally, there was preliminary evidence for the efficacy of mobile interventions. TBIs may be an additional way of delivering evidence-based treatments to eating disorder patients and their use is likely to increase in the near future. TBIs may also be considered for the prevention of eating disorders and to support carers of eating disorder patients. Areas of future research and important issues such as guidance, therapeutic alliance, and dissemination are discussed.

  13. Mood instability and impulsivity as trait predictors of suicidal thoughts.

    PubMed

    Peters, Evyn M; Balbuena, Lloyd; Marwaha, Steven; Baetz, Marilyn; Bowen, Rudy

    2016-12-01

    Impulsivity, the tendency to act quickly without adequate planning or concern for consequences, is a commonly cited risk factor for suicidal thoughts and behaviour. There are many definitions of impulsivity and how it relates to suicidality is not well understood. Mood instability, which describes frequent fluctuations of mood over time, is a concept related to impulsivity that may help explain this relationship. The purpose of this study was to determine whether impulsivity could predict suicidal thoughts after controlling for mood instability. This study utilized longitudinal data from the 2000 Adult Psychiatric Morbidity Survey (N = 2,406). There was a time interval of 18 months between the two waves of the study. Trait impulsivity and mood instability were measured with the Structured Clinical Interview for DSM-IV Axis II Personality Disorders. Logistic regression analyses were used to evaluate baseline impulsivity and mood instability as predictors of future suicidal thoughts. Impulsivity significantly predicted the presence of suicidal thoughts, but this effect became non-significant with mood instability included in the same model. Impulsivity may be a redundant concept when predicting future suicidal thoughts if mood instability is considered. The significance is that research and therapy focusing on mood instability along with impulsivity may be useful in treating the suicidal patient. Mood instability and impulsivity both predict future suicidal thoughts. Impulsivity does not predict suicidal thoughts after controlling for mood instability. Assessing and treating mood instability could be important aspects of suicide prevention and risk management. © 2015 The British Psychological Society.

  14. The role of automatic control in future interplanetary spaceflight

    NASA Technical Reports Server (NTRS)

    Scull, J. R.; Moore, J. W.

    1976-01-01

    The paper reviews the guidance and automatic control techniques used in previous U.S. and Soviet lunar and planetary exploration spacecraft, and examines the objectives and requirements of potential future interplanetary missions from the viewpoint of their further demands on automatic control technology. These missions include the Venus orbital imaging radar mission, the Pioneer Mars penetrator mission, the Mars surface sample return mission, Pioneer Saturn/Uranus/Titan probe missions, the Mariner Jupiter orbiter with daughter satellite, and comet and asteroid missions.

  15. A survey of experiments and experimental facilities for active control of flexible structures

    NASA Technical Reports Server (NTRS)

    Sparks, Dean W., Jr.; Horner, Garnett C.; Juang, Jer-Nan; Klose, Gerhard

    1989-01-01

    A brief survey of large space structure control related experiments and facilities was presented. This survey covered experiments performed before and up to 1982, and those of the present period (1982-...). Finally, the future planned experiments and facilities in support of the control-structure interaction (CSI) program were reported. It was stated that new, improved ground test facilities are needed to verify the new CSI design techniques that will allow future space structures to perform planned NASA missions.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bunch, Kyle J.; Williams, Laura S.; Jones, Anthony M.

    The 2010 ratification of the New START Treaty has been widely regarded as a noteworthy national security achievement for both the Obama administration and the Medvedev-Putin regime, but deeper cuts are envisioned under future arms control regimes. Future verification needs will include monitoring the storage of warhead components and fissile materials and verifying dismantlement of warheads, pits, secondaries, and other materials. From both the diplomatic and technical perspectives, verification under future arms control regimes will pose new challenges. Since acceptable verification technology must protect sensitive design information and attributes, non-nuclear non-sensitive signatures may provide a significant verification tool without themore » use of additional information barriers. The use of electromagnetic signatures to monitor nuclear material storage containers is a promising technology with the potential to fulfill these challenging requirements. Research performed at Pacific Northwest National Laboratory (PNNL) has demonstrated that low frequency electromagnetic signatures of sealed metallic containers can be used to confirm the presence of specific components on a “yes/no” basis without revealing classified information. Arms control inspectors might use this technique to verify the presence or absence of monitored items, including both nuclear and non-nuclear materials. Although additional research is needed to study signature aspects such as uniqueness and investigate container-specific scenarios, the technique potentially offers a rapid and cost-effective tool to verify reduction and dismantlement of U.S. and Russian nuclear weapons.« less

  17. Analogue Simulation of human and psychosocial factors for MoonMars bases

    NASA Astrophysics Data System (ADS)

    Davidová, Lucie; Foing, Bernard

    2017-04-01

    Several courageous plans regarding future human space exploration have been proposed. Both main future targets, ESA's Moon village, as well as journey to Mars represent huge challenge for humans. Appropriate research on psychological aspects of humans in extreme conditions is needed. Analogue simulations represent valuable source of information that help us to understand how to provide an adequate support to astronauts in specific conditions of isolation and limited resources. The psychosocial investigation was designed to builds on combination of several methods based on subjective as well as objective assessments, namely observation, sociomapping, content analysis of interviews etc. Research on several simulations provided lessons learned and various insights. The attention was paid particularly to the interpersonal interactions among crew members, intragroup as well as intergroup communication, cooperation, and performance. This comprehensive approach enables early detection of hidden structures and potential insufficiencies of an astronaut team. The sociomapping of interpersonal communication as well as analysis of interviews with participants revealed insufficiencies especially in communication between the analogue astronauts and mission control. Another important finding was gain by investigation of the relationship between the astronaut crew and mission control. Astronauts low trust to mission control can have a great negative impact to the performance and well-being of astronauts. The findings of the psychosocial studies are very important for designing astronaut training and planning future mission.

  18. The benefits from complying with the framework convention on tobacco control: a SimSmoke analysis of 15 European nations.

    PubMed

    Levy, David T; Huang, An-Tsun; Currie, Laura M; Clancy, Luke

    2014-12-01

    This article compares the predicted impact of tobacco tax increases alone and as part of a comprehensive tobacco control strategy on smoking prevalence and smoking-attributable deaths (SADs) across 15 European countries. Country-specific population, smoking prevalence and policy data with modified parameter values have been applied to the previously validated SimSmoke model for 10 high-income and 5 middle-income European nations. The impact of past and potential future policies is modelled. Models generally validated well across the 15 countries, and showed the impact of past policies. Without stronger future policies, 44 million lives would be lost due to smoking across the 15 study countries between 2011 and 2040, but effective policies could avert 7.7 million of those premature deaths. Results suggest that past policies have been effective in reducing smoking rates, but there is also a strong potential for future policies consistent with the Framework Convention on Tobacco Control. When specific taxes are increased to 70% of retail price, strong smoke-free air laws, youth access laws and marketing restrictions are enforced, stronger health warnings are implemented, and cessation treatment and media campaigns are supported, smoking prevalence and SADs will fall substantially in European countries. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine © The Author 2013; all rights reserved.

  19. Temporal discounting of monetary rewards in children and adolescents with ADHD and autism spectrum disorders.

    PubMed

    Demurie, Ellen; Roeyers, Herbert; Baeyens, Dieter; Sonuga-Barke, Edmund

    2012-11-01

    It has been difficult to differentiate attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in terms of some aspects of their cognitive profile. While both show deficits in executive functions, it has been suggested that they may differ in their response to monetary reward. For instance, children with ADHD prefer small immediate over large delayed rewards more than typically developing controls. One explanation for this is that they discount the value of rewards to a higher degree as they are moved into the future. The current study investigated whether children with ADHD can be differentiated from those with ASD in terms of reward discounting. Thirty-nine children (8-16 y) with ADHD, 34 children with ASD and 46 typically developing controls performed a hypothetical monetary temporal discounting task. Participants were instructed to make repeated choices between small variable rewards (0, 5, 10, 20, 30€) delivered immediately and large rewards delivered after a variable delay. Children with ADHD but not ASD discounted future rewards at a higher rate than typically developing controls. These data confirm steeper discounting of future rewards in ADHD and add to a small but growing literature showing that the psychological profile of ADHD can be distinguished from that of ASD in terms of disrupted motivational processes. © 2012 Blackwell Publishing Ltd.

  20. No smoke without fire: The impact of future friends on adolescent smoking behaviour.

    PubMed

    Mercken, L; Candel, M; van Osch, L; de Vries, H

    2011-02-01

    This study examined the impact of future friends and the contribution of different social influence and selection processes in predicting adolescents' smoking behaviour by extending the theory of planned behaviour (TPB). We investigated the impact of previous smoking, direct pressure from friends, descriptive norms of present and future friends, smoking-based selection of future friends, and distinguished between reciprocal and desired friends. A longitudinal design with three measurements was used. METHODSL: The sample consisted of 1,475 Dutch high school students (mean age = 12.7 years) that participated as a control group in the European Smoking prevention Framework Approach study at three measurements. Structural equation modelling revealed that adolescent smoking was influenced by intention, previous smoking, descriptive norms of parents and siblings, and that desired as well as reciprocal friends were selected based on similar smoking behaviour. Future friends indirectly influenced adolescent smoking through intention, as did attitude, subjective norms of parents and siblings, previous smoking, and descriptive norms of reciprocal friends and siblings. The present results suggest that descriptive norms and selection of friends need to be considered as major factors explaining smoking behaviour among adolescents besides the TPB components. These insights contribute to the further refinement of smoking prevention strategies. ©2010 The British Psychological Society.

  1. The Internet and the Independence of Individuals with Disabilities.

    ERIC Educational Resources Information Center

    Grimaldi, Caroline; Goette, Tanya

    1999-01-01

    This study examined the role of the Internet and its usage on the level of perceived independence among people with physical disabilities. Discusses independence, perceived control, psychological self-reliance, adaptive technology, hypotheses tested, and future directions. A copy of one of the questionnaires used is appended. (Author/LRW)

  2. Pilot interaction with automated airborne decision making systems

    NASA Technical Reports Server (NTRS)

    Rouse, W. B.

    1981-01-01

    The role of the pilot and crew for future aircraft is discussed. Fifteen formal experimental studies and the development of a variety of models of human behavior based on queueing history, pattern recognition methods, control theory, fuzzy set theory, and artificial intelligence concepts are presented. L.F.M.

  3. EVALUATION AND INTERPRETATION OF NEURODEVELOPMENTAL ENDPOINTS FOR HUMAN HEALTH RISK ASSESSMENT -- POSITIVE CONTROL STUDIES, NORMAL VARIABILITY AND STATISTICAL ISSUES.

    EPA Science Inventory

    ILSI Research Foundation/Risk Science Institute convened an expert working group to assess the lessons learned from the implementation of the EPA Developmental Neurotoxicity (DNT) Guideline and provide guidance for future use. The group prepared manuscripts in five areas: public ...

  4. The Human Performance Envelope: Past Research, Present Activities and Future Directions

    NASA Technical Reports Server (NTRS)

    Edwards, Tamsyn

    2017-01-01

    Air traffic controllers (ATCOs) must maintain a consistently high level of human performance in order to maintain flight safety and efficiency. In current control environments, performance-influencing factors such as workload, fatigue and situation awareness can co-occur, and interact, to effect performance. However, multifactor influences and the association with performance are under-researched. This study utilized a high fidelity human in the loop enroute air traffic control simulation to investigate the relationship between workload, situation awareness and ATCO performance. The study aimed to replicate and extend Edwards, Sharples, Wilson and Kirwans (2012) previous study and confirm multifactor interactions with a participant sample of ex-controllers. The study also aimed to extend Edwards et als previous research by comparing multifactor relationships across 4 automation conditions. Results suggest that workload and SA may interact to produce a cumulative impact on controller performance, although the effect of the interaction on performance may be dependent on the context and amount of automation present. Findings have implications for human-automation teaming in air traffic control, and the potential prediction and support of ATCO performance.

  5. Contemporary Australian outcomes in childhood and adolescent type 1 diabetes: 10 years post the Diabetes Control and Complications Trial.

    PubMed

    Ambler, Geoffrey R; Fairchild, Jan; Craig, Maria E; Cameron, Fergus J

    2006-01-01

    The reporting of the results of the Diabetes Control and Complications Trial in 1993 has led to a major reappraisal of management practices and outcomes in type 1 diabetes in children and adolescents. A considerable body of outcome data has been generated from Australia in this post-Diabetes Control and Complications Trial era relating to incidence, metabolic control, growth, hypoglycaemia, microvascular and macrovascular complications, cognition, behaviour and quality of life. These data are important in planning future management strategies and resource allocation and as a basis for future research.

  6. NOx emissions in China: historical trends and future perspectives

    NASA Astrophysics Data System (ADS)

    Zhao, B.; Wang, S. X.; Liu, H.; Xu, J. Y.; Fu, K.; Klimont, Z.; Hao, J. M.; He, K. B.; Cofala, J.; Amann, M.

    2013-10-01

    Nitrogen oxides (NOx) are key pollutants for the improvement of ambient air quality. Within this study we estimated the historical NOx emissions in China for the period 1995-2010, and calculated future NOx emissions every five years until 2030 under six emission scenarios. Driven by the fast growth of energy consumption, we estimate the NOx emissions in China increased rapidly from 11.0 Mt in 1995 to 26.1 Mt in 2010. Power plants, industry and transportation were major sources of NOx emissions, accounting for 28.4%, 34.0%, and 25.4% of the total NOx emissions in 2010, respectively. Two energy scenarios, a business as usual scenario (BAU) and an alternative policy scenario (PC), were developed to project future energy consumption. In 2030, total energy consumption is projected to increase by 64% and 27% from 2010 level respectively. Three sets of end-of-pipe pollution control measures, including baseline, progressive, and stringent control case, were developed for each energy scenario, thereby constituting six emission scenarios. By 2030, the total NOx emissions are projected to increase (compared to 2010) by 36% in the baseline while policy cases result in reduction up to 61% in the most ambitious case with stringent control measures. More than a third of the reduction achieved by 2030 between least and most ambitious scenario comes from power sector, and more than half is distributed equally between industry and transportation sectors. Selective catalytic reduction dominates the NOx emission reductions in power plants, while life style changes, control measures for industrial boilers and cement production are major contributors to reductions in industry. Timely enforcement of legislation on heavy-duty vehicles would contribute significantly to NOx emission reductions. About 30% of the NOx emission reduction in 2020 and 40% of the NOx emission reduction in 2030 could be treated as the ancillary benefit of energy conservation. Sensitivity analysis was conducted to explore the impact of key factors on future emissions.

  7. Microbial control in Asia: a bellwether for the future?

    PubMed

    Gelernter, Wendy D

    2007-07-01

    Advances and barriers faced by microbial control efforts in Asia offer instructive insights for microbial control in general. The papers in this series, which are based on plenary lectures given at the Society for Invertebrate Pathology 2006 meeting in Wuhan, China, explore the history and current status of microbial control in China, Japan, and Southeast Asia, and in doing so, bring to light the following key assumptions that deserve further examination; (1) the adoption rate of microbial control is well documented; (2) microbial control agents can compete directly with conventional insecticides; (3) microbial control agents are relatively easy and inexpensive to produce and develop; (4) patents will promote innovation and investor interest in microbial control. Alternative viewpoints are presented that can hopefully aid in future efforts to develop more safe and effective microbial control agents.

  8. Methodological standards and interpretation of video-electroencephalography in adult control rodents. A TASK1-WG1 report of the AES/ILAE Translational Task Force of the ILAE.

    PubMed

    Kadam, Shilpa D; D'Ambrosio, Raimondo; Duveau, Venceslas; Roucard, Corinne; Garcia-Cairasco, Norberto; Ikeda, Akio; de Curtis, Marco; Galanopoulou, Aristea S; Kelly, Kevin M

    2017-11-01

    In vivo electrophysiological recordings are widely used in neuroscience research, and video-electroencephalography (vEEG) has become a mainstay of preclinical neuroscience research, including studies of epilepsy and cognition. Studies utilizing vEEG typically involve comparison of measurements obtained from different experimental groups, or from the same experimental group at different times, in which one set of measurements serves as "control" and the others as "test" of the variables of interest. Thus, controls provide mainly a reference measurement for the experimental test. Control rodents represent an undiagnosed population, and cannot be assumed to be "normal" in the sense of being "healthy." Certain physiological EEG patterns seen in humans are also seen in control rodents. However, interpretation of rodent vEEG studies relies on documented differences in frequency, morphology, type, location, behavioral state dependence, reactivity, and functional or structural correlates of specific EEG patterns and features between control and test groups. This paper will focus on the vEEG of standard laboratory rodent strains with the aim of developing a small set of practical guidelines that can assist researchers in the design, reporting, and interpretation of future vEEG studies. To this end, we will: (1) discuss advantages and pitfalls of common vEEG techniques in rodents and propose a set of recommended practices and (2) present EEG patterns and associated behaviors recorded from adult rats of a variety of strains. We will describe the defining features of selected vEEG patterns (brain-generated or artifactual) and note similarities to vEEG patterns seen in adult humans. We will note similarities to normal variants or pathological human EEG patterns and defer their interpretation to a future report focusing on rodent seizure patterns. Wiley Periodicals, Inc. © 2017 International League Against Epilepsy.

  9. Influence of stimulants on electrodermal studies in Fragile X syndrome.

    PubMed

    Hagerman, Randi J; Miller, Lucy J; McGrath-Clarke, Jude; Riley, Karen; Goldson, Edward; Harris, Susan W; Simon, Jody; Church, Kelly; Bonnell, Julie; Ognibene, Todd C; McIntosh, Daniel N

    2002-05-01

    Attention Deficit Hyperactivity Disorder (ADHD) is seen in the majority of children with Fragile X Syndrome (FraX). Previous work has documented an enhanced sweat response to stimuli in children with FraX compared to controls utilizing electrodermal response (EDR) measures. The present study assesses the EDRs both on and off stimulants in 19 children with ADHD and FraX compared to 17 age- and IQ-matched control patients with ADHD and developmental delays. Although the baseline EDRs were comparable between FraX patients and controls, the patients with FraX had a significant decrease in EDR amplitude and number of peaks when treated with stimulants compared to controls. This suggests that patients with FraX are more responsive to the enhancement of inhibitory systems that occur with stimulant use for ADHD. The use of a quantifiable measure, such as EDR, is recommended in future studies of treatment efficacy. Copyright 2002 Wiley-Liss, Inc.

  10. Are Common Skin Diseases among Norwegian Dermatological Outpatients Associated with Psychological Problems Compared with Controls? An Observational Study.

    PubMed

    Balieva, Flora; Lien, Lars; Kupfer, Jörg; Halvorsen, Jon Anders; Dalgard, Florence

    2016-02-01

    Dermatological disease has been shown to be associated with psychological comorbidity. The aim of this observational study is to describe the distribution of skin disease and the prevalence of depression, anxiety and stress among Norwegian dermatological outpatients. Thirteen percent of outpatients had clinical anxiety compared with 3.7% of healthy controls, and 5.8% had clinical depression compared with 0.9% of controls. Adjusted odds ratio for clinical anxiety was 4.53 in patients compared with controls, and for clinical depression 6.25, which is much higher than previously described in a larger European study. Patients with tumours had less depression. Chronic inflammatory skin conditions had an especially high impact on patient's psychological wellbeing and should not be undervalued relative to, for instance, skin cancer in health strategies. These results argue strongly for including skin disease prevention and treatment in future health strategies.

  11. A case control study of senile cataract in a hospital based population.

    PubMed

    Badrinath, S S; Sharma, T; Biswas, J; Srinivas, V

    1996-12-01

    A case-control study (244 cases and 264 controls) was done during 1986-89 on a hospital based population to evaluate the risk factors associated with the etiology of senile cataract. Patient with age between 40-60 years, visual acuity of 6/9 or less, and presence of lenticular opacity of senile origin were included as cases. Age matched individuals with absence of lenticular opacity made up the controls. Multivariate logistic regression analysis revealed that higher systolic BP and number of meals were significantly (P < or = 0.05) associated with presence of senile cataract; whereas higher weight, education and income, and utilization of cooking water had a significant protective effect against senile cataract. The present study helps the clinician to understand the possible risk factors associated with the development of senile cataract and could be helpful in designing a intervention strategy in future.

  12. Social class, sense of control, and social explanation.

    PubMed

    Kraus, Michael W; Piff, Paul K; Keltner, Dacher

    2009-12-01

    Lower social class is associated with diminished resources and perceived subordinate rank. On the basis of this analysis, the authors predicted that social class would be closely associated with a reduced sense of personal control and that this association would explain why lower class individuals favor contextual over dispositional explanations of social events. Across 4 studies, lower social class individuals, as measured by subjective socioeconomic status (SES), endorsed contextual explanations of economic trends, broad social outcomes, and emotion. Across studies, the sense of control mediated the relation between subjective SES and contextual explanations, and this association was independent of objective SES, ethnicity, political ideology, and self-serving biases. Finally, experimentally inducing a higher sense of control attenuated the tendency for lower subjective SES individuals to make more contextual explanations (Study 4). Implications for future research on social class as well as theoretical distinctions between objective SES and subjective SES are discussed.

  13. Controllability in Multi-Stage Laser Ion Acceleration

    NASA Astrophysics Data System (ADS)

    Kawata, S.; Kamiyama, D.; Ohtake, Y.; Barada, D.; Ma, Y. Y.; Kong, Q.; Wang, P. X.; Gu, Y. J.; Li, X. F.; Yu, Q.

    2015-11-01

    The present paper shows a concept for a future laser ion accelerator, which should have an ion source, ion collimators, ion beam bunchers and ion post acceleration devices. Based on the laser ion accelerator components, the ion particle energy and the ion energy spectrum are controlled, and a future compact laser ion accelerator would be designed for ion cancer therapy or for ion material treatment. In this study each component is designed to control the ion beam quality. The energy efficiency from the laser to ions is improved by using a solid target with a fine sub-wavelength structure or a near-critical density gas plasma. The ion beam collimation is performed by holes behind the solid target or a multi-layered solid target. The control of the ion energy spectrum and the ion particle energy, and the ion beam bunching are successfully realized by a multi-stage laser-target interaction. A combination of each component provides a high controllability of the ion beam quality to meet variable requirements in various purposes in the laser ion accelerator. The work was partly supported by MEXT, JSPS, ASHULA project/ ILE, Osaka University, CORE (Center for Optical Research and Education, Utsunomiya University, Japan), Fudan University and CDI (Creative Dept. for Innovation) in CCRD, Utsunomiya University.

  14. Impact of melanoma genetic test reporting on perceived control over melanoma prevention.

    PubMed

    Aspinwall, Lisa G; Stump, Tammy K; Taber, Jennifer M; Kohlmann, Wendy; Leaf, Samantha L; Leachman, Sancy A

    2015-10-01

    To determine whether receiving melanoma genetic test results undermines perceived control over melanoma prevention, control-related beliefs were examined among 60 adults from melanoma-prone families receiving CDKN2A/p16 test results (27 unaffected noncarriers, 15 unaffected carriers, 18 affected carriers; response rate at 2 years = 64.9 % of eligible respondents). Multilevel modeling of perceived control ratings over a 2-year period revealed significant variation in individual trajectories: most participants showed increases (45 %) or no change (38.3 %), while 16.7 % showed decreases. At the group level, noncarriers reported sustained increases through the 2-year follow-up (ps < .05); unaffected carriers reported significant short-term increases (ps < .05); and affected carriers reported no change. Participants in all groups continued to rate photoprotection as highly effective in reducing melanoma risk and reported decreased beliefs that carrying the p16 mutation would inevitably lead to the development of melanoma. Qualitative responses immediately following counseling and test reporting corroborated these findings, as 93 % indicated it was possible to either prevent (64.9 %) or decrease the likelihood (28.1 %) of future melanomas. Thus, genetic test reporting does not generally undermine perceived control over melanoma prevention, though variability in response to positive results warrants future study.

  15. Post-intervention effects on screen behaviours and mediating effect of parental regulation: the HEalth In Adolescents study – a multi-component school-based randomized controlled trial

    PubMed Central

    2014-01-01

    Background To improve effectiveness of future screen behaviour interventions, one needs to know whether an intervention works via the proposed mediating mechanisms and whether the intervention is equally effective among subgroups. Parental regulation is identified as a consistent correlate of screen behaviours, but prospective evidence as well as the mediation role of parental regulation is largely lacking. This study investigated post-intervention main effects on screen behaviours in the HEIA-intervention – a Norwegian school-based multiple-behaviour study, as well as mediation effects of parental regulation by adolescents’ and parents’ report. In addition, moderating effects of gender and weight status on the intervention and mediating effects were explored. Methods Participating schools were randomized to control (n = 25) or intervention (n = 12) condition. Adolescents (n = 908 Control; 510 Intervention) self-reported their weekday and weekend TV-viewing and computer/game-use. Change in adolescents’ behaviours was targeted through school and parents. Adolescents, mothers (n = 591 Control; 244 Interventions) and fathers (n = 469 Control; 199 Intervention) reported parental regulation of the screen behaviours post-intervention (at 20 month). The product-of-coefficient test using linear regression analysis was conducted to examine main and mediating effects. Results There was no intervention effect on the screen behaviours in the total sample. Gender moderated effect on weekend computer/game-use, while weight status moderated the effect on weekday TV-viewing and computer/game-use. Stratified analyses showed a small favourable intervention effect on weekday TV-viewing among the normal weight. Parental regulation did not mediate change in the screen behaviours. However, stronger parental regulation was associated with less TV-viewing and computer/game-use with effects being conditional on adolescents’ versus parental reports. Parental regulation of the screen behaviours, primarily by the parental report, was associated with change in the respective behaviours. Conclusion Multiple behaviour intervention may not affect all equally well, and the effect may differ by weight status and gender. In future interventions parents should be encouraged to regulate their adolescents’ TV-viewing and computer/game-use on both weekdays and weekends as parental regulation was identified as a determinant of these screen behaviours. However, future intervention studies may need to search for more effective intervention strategies targeting parental regulation. Trial registration Current Controlled Trials ISRCTN98552879 PMID:24568125

  16. Electric machine differential for vehicle traction control and stability control

    NASA Astrophysics Data System (ADS)

    Kuruppu, Sandun Shivantha

    Evolving requirements in energy efficiency and tightening regulations for reliable electric drivetrains drive the advancement of the hybrid electric (HEV) and full electric vehicle (EV) technology. Different configurations of EV and HEV architectures are evaluated for their performance. The future technology is trending towards utilizing distinctive properties in electric machines to not only to improve efficiency but also to realize advanced road adhesion controls and vehicle stability controls. Electric machine differential (EMD) is such a concept under current investigation for applications in the near future. Reliability of a power train is critical. Therefore, sophisticated fault detection schemes are essential in guaranteeing reliable operation of a complex system such as an EMD. The research presented here emphasize on implementation of a 4kW electric machine differential, a novel single open phase fault diagnostic scheme, an implementation of a real time slip optimization algorithm and an electric machine differential based yaw stability improvement study. The proposed d-q current signature based SPO fault diagnostic algorithm detects the fault within one electrical cycle. The EMD based extremum seeking slip optimization algorithm reduces stopping distance by 30% compared to hydraulic braking based ABS.

  17. An airline study of advanced technology requirements for advanced high speed commercial transport engines. 1: Engine design study assessment

    NASA Technical Reports Server (NTRS)

    Sallee, G. P.

    1973-01-01

    The advanced technology requirements for an advanced high speed commercial tranport engine are presented. The results of the phase 1 study effort cover the following areas: (1) statement of an airline's major objectives for future transport engines, (2) airline's method of evaluating engine proposals, (3) description of an optimum engine for a long range subsonic commercial transport including installation and critical design features, (4) discussion of engine performance problems and experience with performance degradation, (5) trends in engine and pod prices with increasing technology and objectives for the future, (6) discussion of the research objectives for composites, reversers, advanced components, engine control systems, and devices to reduce the impact of engine stall, and (7) discussion of the airline objectives for noise and pollution reduction.

  18. Mars: Past, Present, and Future. Results from the MSATT Program, part 1

    NASA Technical Reports Server (NTRS)

    Haberle, R. M. (Editor)

    1993-01-01

    This volume contains papers that were accepted for presentation at the workshop on Mars: Past, Present, and Future -- Results from the MSATT Program. Topics include, but are not limited to: Martian impact craters; thermal emission measurements of Hawaiian palagonitic soils with implications for Mars; thermal studies of the Martian surface; Martian atmospheric composition studies; temporal and spatial mapping of Mars' atmospheric dust opacity and surface albedo; studies of atmospheric dust from Viking IR thermal mapper data; the distribution of Martian ground ice at other epochs; numerical simulation of thermally induced near-surface flows over Martian terrain; the pH of Mars; the mineralogic evolution of the Martian surface through time; geologic controls of erosion and sedimentation on Mars; and dielectric properties of Mars' surface: proposed measurement on a Mars Lander.

  19. Analysis of GMO Plum Plant Culture in System Operations Failure

    NASA Technical Reports Server (NTRS)

    Mercado, Dianne

    2017-01-01

    GMO plum trees are being evaluated at the Kennedy Space Center as a possible candidate for future space crops. Previously conducted horticultural testing compared the performance of several plum genotypes in controlled environment chambers, resulting in a down-selection to the NASA-11 genotype. Precursory studies determined the water use requirements to sustain the plants as well as the feasibility of grafting non-GMO plum scions onto GMO plum rootstocks of NASA-5, NASA-10, and NASA-11 genotypes. This study follows the growth and horticultural progress of plum trees and in-vitro cultures from August 2017 to November 2017, and provides supplemental support for future GMO plum studies. The presence of Hurricane Irma in early September 2017 resulted in the plants undergoing material deterioration from major changes to their overall horticultural progress.

  20. Investigations on colour dependent photo induced microactuation effect of FSMA and proposing suitable mechanisms to control the effect

    NASA Astrophysics Data System (ADS)

    Bagchi, A.; Sarkar, S.; Mukhopadhyay, P. K.

    2018-02-01

    Three different coloured focused laser beams were used to study the photo induced microactuation effect found in some ferromagnetic shape memory alloys. Besides trying to uncover the basic causes of this unique and as yet unexplained effect, these studies are to help find other conditions to further characterize the effect for practical use. In this study some mechanisms have been proposed to control the amplitude of actuation of the sample. Control of the actuation of the FSMA sample both linearly with the help of a continuously variable neutral density filter as well periodically with the help of a linear polarizer was achieved. Statistical analysis of the experimental data was also done by applying ANOVA studies on the data to conclusively provide evidence in support of the relationship between the actuation of the sample and the various controlling factors. This study is expected to pave the way to implement this property of the sample in fabricating and operating useful micro-mechanical systems in the near future.

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