Sample records for control group cont

  1. Influence of blood contamination during multimode adhesive application on the microtensile bond strength to dentin.

    PubMed

    Kucukyilmaz, E; Celik, E U; Akcay, M; Yasa, B

    2017-12-01

    The present study evaluated the effects of blood contamination performed at different steps of bonding on the microtensile bond strength (μTBS) of multimode adhesives to dentin when using the self-etch approach. Seventy-five molars were randomly assigned to three adhesive groups comprising 25 specimens each: two multimode adhesives [Single Bond Universal (SBU) and All-Bond Universal (ABU)] and a conventional one-step self-etch adhesive [Clearfil S3 Bond Plus (CSBP)]. Each group was subdivided as follows: (1) uncontaminated (control): bonding application/light curing as a positive control; (2) contamination-1 (cont-1): bonding application/light curing/blood contamination/dry as a negative control; (3) contamination-2 (cont-2): bonding application/light curing/blood contamination/rinse/dry; (4) contamination-3 (cont-3): bonding application/blood contamination/dry/bonding re-application/light curing; and (5) contamination-4 (cont-4): bonding application/blood contamination/rinse/dry/bonding re-application/light curing. Dentin specimens were prepared for μTBS testing after the composite resin application. Data were analyzed with two-way ANOVA and post-hoc tests (α = 0.05). μTBS values were similar in cont-3 groups, and ABU/cont-4 and corresponding control groups, but were significantly lower in the other groups than in their control groups (P < 0.05). Cont-1 groups showed the lowest μTBS values (P < 0.05). Neither decontamination method prevented the decrease in μTBS when contamination occurred after light curing. Drying the blood contaminants and reapplying the adhesive may regain the dentin adhesion when contamination occurs before light curing. Alternatively, rinsing and drying contaminants followed by adhesive re-application may be effective depending on adhesive type.

  2. Brain activity in adults who stutter: Similarities across speaking tasks and correlations with stuttering frequency and speaking rate

    PubMed Central

    Ingham, Roger J.; Grafton, Scott T.; Bothe, Anne K.; Ingham, Janis C.

    2012-01-01

    Many differences in brain activity have been reported between persons who stutter (PWS) and typically fluent controls during oral reading tasks. An earlier meta-analysis of imaging studies identified stutter-related regions, but recent studies report less agreement with those regions. A PET study on adult dextral PWS (n = 18) and matched fluent controls (CONT, n = 12) is reported that used both oral reading and monologue tasks. After correcting for speech rate differences between the groups the task-activation differences were surprisingly small. For both analyses only some regions previously considered stutter-related were more activated in the PWS group than in the CONT group, and these were also activated during eyes-closed rest (ECR). In the PWS group, stuttering frequency was correlated with cortico-striatal-thalamic circuit activity in both speaking tasks. The neuroimaging findings for the PWS group, relative to the CONT group, appear consistent with neuroanatomic abnormalities being increasingly reported among PWS. PMID:22564749

  3. Prevalence of overweight and obesity in children and adolescents with type 1 diabetes mellitus.

    PubMed

    Sandhu, Naminder; Witmans, Manisha B; Lemay, Jean-François; Crawford, Susan; Jadavji, Nadeem; Pacaud, Danièle

    2008-07-01

    Information about the prevalence of obesity in children with type 1 diabetes mellitus (DM1) is inconsistent and limited. The burden of the concurrent problems of obesity and DM1 can have notable medical, psychological, and social implications for both patients and their families. To determine prevalences of overweight and obesity in children with DM1 compared to a control population. In a cross-sectional study, we compared the prevalence of overweight/obesity in 390 children with DM1 (males 54%) and 565 controls (CONT; males 60%) aged 6 to 16 years. Overweight and obesity were defined as body mass indices between the 85th and 95th percentiles, and greater than the 95th percentile for age, respectively. Overall, 29.5% DM1 and 18.1% CONT (p < 0.001) were either obese or overweight. The prevalence of obesity alone did not differ (DM1 5.4% vs CONT 8.2%), but a greater rate of overweight was seen in the DM1 group (DM 24.1% vs CONT 10.0%, p < 0.001). Rate's of overweight were higher in the DM1 than CONT across all age groups and in both genders (males: DM1 20.1% vs CONT 8.9%, p < 0.001; females: DM1 28.7% vs CONT 11.5%, p < 0.001). Only females showed an increase in overall overweight/obesity rate (DM1 34.8% vs CONT 16.4%, p < 0.001) and this was most evident in older girls. Children with DM1 are more overweight, but not more obese, than their nondiabetic counterparts. Additional research is warranted to evaluate the characteristics of DM1 and its management that may influence weight gain.

  4. Repeated blood flow restriction induces muscle fiber hypertrophy.

    PubMed

    Sudo, Mizuki; Ando, Soichi; Kano, Yutaka

    2017-02-01

    We recently developed an animal model to investigate the effects of eccentric contraction (ECC) and blood flow restriction (BFR) on muscle tissue at the cellular level. This study clarified the effects of repeated BFR, ECC, and BFR combined with ECC (BFR+ECC) on muscle fiber hypertrophy. Male Wistar rats were assigned to 3 groups: BFR, ECC, and BFR+ECC. The contralateral leg in the BFR group served as a control (CONT). Muscle fiber cross-sectional area (CSA) of the tibialis anterior was determined after the respective treatments for 6 weeks. CSA was greater in the BFR+ECC group than in the CONT (P < 0.01) and ECC (P < 0.05) groups. CSA was greater in the BFR group than that in the CONT group (P < 0.05). These results suggest that repeated BFR alone as well as BFR+ECC induces muscle fiber hypertrophy at the cellular level. Muscle Nerve 55: 274-276, 2017. © 2016 Wiley Periodicals, Inc.

  5. Intermittent whole-body vibration attenuates a reduction in the number of the capillaries in unloaded rat skeletal muscle.

    PubMed

    Kaneguchi, Akinori; Ozawa, Junya; Kawamata, Seiichi; Kurose, Tomoyuki; Yamaoka, Kaoru

    2014-09-26

    Whole-body vibration has been suggested for the prevention of muscle mass loss and muscle wasting as an attractive measure for disuse atrophy. This study examined the effects of daily intermittent whole-body vibration and weight bearing during hindlimb suspension on capillary number and muscle atrophy in rat skeletal muscles. Sixty male Wistar rats were randomly divided into four groups: control (CONT), hindlimb suspension (HS), HS + weight bearing (WB), and HS + whole-body vibration (VIB) (n = 15 each). Hindlimb suspension was applied for 2 weeks in HS, HS + WB, and HS + VIB groups. During suspension, rats in HS + VIB group were placed daily on a vibrating whole-body vibration platform for 20 min. In HS + WB group, suspension was interrupted for 20 min/day, allowing weight bearing. Untreated rats were used as controls. Soleus muscle wet weights and muscle fiber cross-sectional areas (CSA) significantly decreased in HS, HS + WB, and HS + VIB groups compared with CONT group. Both muscle weights and CSA were significantly greater in HS + WB and HS + VIB groups compared with HS group. Capillary numbers (represented by capillary-to-muscle fiber ratio) were significantly smaller in all hindlimb suspension-treated groups compared with CONT group. However, a reduction in capillary number by unloading hindlimbs was partially prevented by whole-body vibration. These findings were supported by examining mRNA for angiogenic-related factors. Expression levels of a pro-angiogenic factor, vascular endothelial growth factor-A mRNA, were significantly lower in all hindlimb suspension-treated groups compared with CONT group. There were no differences among hindlimb suspension-treated groups. Expression levels of an anti-angiogenic factor, CD36 (receptor for thrombospondin-1) mRNA, were significantly higher in all hindlimb suspension-treated groups compared with CONT group. Among the hindlimb suspension-treated groups, expression of CD36 mRNA in HS + VIB group tended to be suppressed (less than half the HS group). Our results suggest that weight bearing with or without vibration is effective for disuse-derived disturbance by preventing muscle atrophy, and whole-body vibration exercise has an additional benefit of maintaining microcirculation of skeletal muscle.

  6. Altered biomechanical strategies and medio-lateral control of the knee represent incomplete recovery of individuals with injury during single leg hop.

    PubMed

    Roos, Paulien E; Button, Kate; Sparkes, Valerie; van Deursen, Robert W M

    2014-02-07

    Anterior cruciate ligament (ACL) injury can result in failure to return to pre-injury activity levels and future osteoarthritis predisposition. Single leg hop is used in late rehabilitation to evaluate recovery and inform treatment but biomechanical understanding of this activity is insufficient. This study investigated single leg hop for distance aiming to evaluate if ACL patients had recovered: (1) landing strategies and (2) medio-lateral knee control. We hypothesized that patients with reconstructive surgery (ACLR) would have more similar landing strategies and knee control to healthy controls than patients treated conservatively (ACLD). 16 ACLD and 23 ACLR subjects were compared to 20 healthy controls (CONT). Kinematic and ground reaction force data were collected while subjects hopped their maximum distance. The main output parameters were hop distance, peak knee flexor angles and extensor moments and Fluency (a measure introduced to represent medio-lateral knee control). Statistical differences between ACL and control groups were analyzed using a general linear model univariate analysis, with COM velocity prior to landing as covariate. Hop distance was the smallest for ACLD and largest for CONT (p<0.001; ACLD 57.1±14.1; ACLR 75.1±17.8; CONT 77.7±14.07% height). ACLR used a similar kinematic strategy to CONT, but had a reduced peak knee extensor moment (p<0.001; ACLD 0.32±0.14; ACLR 0.31±0.16; CONT 0.42±0.13 BW.height). Fluency was reduced in both ACLD and ACLR (p=0.006; ACLD 0.13±0.34; ACLR 0.14±0.34; CONT 0.17±0.41s). Clinical practice uses hopping distance to evaluate ACL patients' recovery. This study demonstrated that aspects such as movement strategies and knee control need to be evaluated. © 2013 Published by Elsevier Ltd.

  7. Effects of a charcoal powder-wood vinegar compound solution in piglets for raw pigeon pea seed meal.

    PubMed

    Mekbungwan, A; Yamauchi, K; Sakaida, T; Buwjoom, T

    2008-03-01

    Histological intestinal villus alterations were studied in piglets fed a raw pigeon pea meal (PM) diet including a powder mixture of amorphous charcoal carbon and wood vinegar compound solution (CWVC). Twenty-eight male castrated piglets were divided into seven dietary groups of four piglets each. The control group was fed raw PM supplemented to the basal diet (178 g/kg crude protein, 4.23 kcal/g gross energy) at 0 g/kg (CONT), 200 g/kg (PM200) and 400 g/kg (PM400). The treatment groups were fed CWVC in both PM200 and PM400 diet groups at levels of 10 g/kg and 30 g/kg (PM200 + CWVC10, PM200 + CWVC30, PM400 + CWVC10 and PM400 + CWVC30). With increasing dietary PM levels, daily feed intake tended to increase. In contrast, daily body-weight gain tended to decrease, significantly in the PM400 group (P < 0.05), resulting in a significant decrease of feed efficiency in PM groups (P < 0.05). Body-weight gain and feed efficiency were higher in the CWVC groups compared with the PM groups. The duodenum and ileum were longer (P < 0.05) in the PM400 group than in CONT, but were similar to CONT in CWVC groups. The liver was heavier (P < 0.05), whereas the weights of the heart, kidney and stomach were decreased in the CWVC groups than in other groups. Most values for the intestinal villus height, cell area and cell mitosis number were lower in PM groups than those in CONT (P < 0.05) for each intestinal segment; however, these values were higher in CWVC groups than in PM groups (P < 0.05). The epithelial cells on the duodenal villus surface of the PM200 group showed cell morphology almost similar to CONT. However, the PM400 group had a smooth villus surface due to the presence of flat cells. The epithelial cells of the CWVC groups were protuberated, resulting in a much rougher surface than CONT. The current growth performance and histological intestinal alterations in piglets fed PM and PM + CWVC diets demonstrate that the intestinal features might be atrophied by feeding PM, resulting in decreased growth performance. CWVC might prevent the harmful effects of PM dietary toxins on intestinal function, resulting in a normal growth performance.

  8. Effects of local vibration and pulsed electromagnetic field on bone fracture: A comparative study.

    PubMed

    Bilgin, Hakkı Murat; Çelik, Ferhat; Gem, Mehmet; Akpolat, Veysi; Yıldız, İsmail; Ekinci, Aysun; Özerdem, Mehmet Siraç; Tunik, Selçuk

    2017-07-01

    The effectiveness of various therapeutic methods on bone fracture has been demonstrated in several studies. In the present study, we tried to evaluate the effect of local low-magnitude, high-frequency vibration (LMHFV) on rat tibia fracture in comparison with pulsed electromagnetic fields (PEMF) during the healing process. Mid-diaphysis tibiae fractures were induced in 30 Sprague-Dawley rats. The rats were assigned into groups such as control (CONT), LMHFV (15 min/day, 7 days/week), and PEMF (3.5 h/day, 7 days/week) for a three-week treatment. Nothing was applied to control group. Radiographs, serum osteocalcin levels, and stereological bone analyses of the three groups were compared. The X-rays of tibiae were taken 21 days after the end of the healing process. PEMF and LMHFV groups had more callus formation when compared to CONT group; however, the difference was not statistically significant (P = 0.375). Serum osteocalcin levels were elevated in the experimental groups compared to CONT (P ≤ 0.001). Stereological tests also showed higher osteogenic results in experimental groups, especially in LMHFV group. The results of the present study suggest that application of direct local LMHFV on fracture has promoted bone formation, showing great potential in improving fracture outcome. Bioelectromagnetics. 38:339-348, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  9. Gait alterations in the UAE population with and without diabetic complications using both traditional and entropy measures.

    PubMed

    Khalaf, Kinda; Al-Angari, Haitham M; Khandoker, Ahsan H; Lee, Sungmun; Almahmeed, Wael; Al Safar, Habiba S; Jelinek, Herbert F

    2017-10-01

    Diabetic foot, one of the most common and debilitating manifestations of type 2 diabetes mellitus (T2DM), is the leading cause of worldwide non-traumatic lower extremity amputations. Diabetics who are at risk of ulceration are currently mainly identified by a thorough clinical examination of the feet, which typically does not show clear symptoms during the early stages of disease progression. In this study, we used a non-linear dynamics tool, gait entropy (GaitEN), in addition to traditional linear gait analysis methods, to investigate gait alterations amongst diabetic patients with combinations of three types of T2DM related complications: retinopathy, diabetic peripheral neuropathy (DPN) and nephropathy. Peak plantar pressure (PPP) was not significantly different in the group with DPN as compared to the control group (diabetics with no complications, CONT) in the forefoot region (DPN: mean±SD: 396±69.4kPa, CONT: 409±68.9kPa), although it was significantly lower in the heel region (DPN: mean±SD: 285±43.1.4kPa, CONT: 295±61.8kPa). On the other hand, gait entropy was significantly lower for the DPN compared to CONT group (DPN: 0.95±0.34, CONT: 1.03±0.28, p<0.05). The significant low entropy was maintained when neuropathy was combined with either retinopathy or nephropathy. For the group with all three complications (ALL-C), the entropy was higher than CONT (ALL-C: 1.07±0.26). This may indicate an intrinsic sensorimotor feedback mechanism for the DPN patients to regulate their gait. However, this feedback gets weaker as patients develop multiple complications. Further analysis with longer walking time and different speeds is needed to verify the entropy results. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Nandrolone decanoate determines cardiac remodelling and injury by an imbalance in cardiac inflammatory cytokines and ACE activity, blunting of the Bezold-Jarisch reflex, resulting in the development of hypertension.

    PubMed

    Franquni, João Vicente Maggioni; do Nascimento, Andrews Marques; de Lima, Eweliny Miranda; Brasil, Girlândia Alexandre; Heringer, Otávio Arruda; Cassaro, Karla Oliveira Dos Santos; da Cunha, Thony Vinicius Pita; Musso, Carlos; Silva Santos, Maria Carmen L F; Kalil, Ieda Carneiro; Endringer, Denise Coutinho; Boëchat, Giovanna Assis Pereirra; Bissoli, Nazaré Souza; de Andrade, Tadeu Uggere

    2013-03-01

    The aims of this study were to evaluate the effects of nandrolone (ND) on cardiac inflammatory cytokines, ACE activity, troponin I, and the sensitivity of the Bezold-Jarisch reflex (BJR). Male Wistar rats were administered either ND (20 mg/kg; DECA) or vehicle (control animals; CONT) for 4 weeks. BJR was analyzed by measuring the bradycardia and hypotension responses elicited by serotonin administration (2-32 μg/kg). Mean arterial pressure (MAP) was assessed and myocyte hypertrophy was determined by the heart weight/body weight ratio and by morphometric analysis. Matrix collagen deposition was assessed by histological analysis of the picrosirius red-stained samples. Mesenteric vascular reactivity was performed and central venous pressure (CVP) evaluated. Cardiac inflammatory cytokine levels and angiotensin-converting enzyme (ACE) activity were studied as well the biomarker of cardiac lesion, troponin I. DECA group showed enhancement of matrix type I collagen deposition (p < 0.01) and cardiac ACE activity (p < 0.01) compared with the CONT. Interleukin (IL)-10 was reduced (p < 0.01) and pro-inflammatory cytokines (TNF-α and IL-6; p < 0.01) were increased in the DECA group compared with CONT. Cardiac injury was observed in the DECA group shown by the reduction in cardiac troponin I (p < 0.01) compared with the CONT group. Animals in the DECA group also developed myocyte hypertrophy and reduction of BJR sensitivity. The MAP of animals treated with ND reached hypertensive levels (p < 0.01; compared with CONT). No changes in CVP and vascular reactivity were observed in both experimental groups. We conclude that high doses of ND elicit cardiotoxic effects with cardiac remodelling and injury. Cardiac changes reduce the BJR sensitivity. Together, these abnormalities contributed to the development of hypertension in animals in the DECA group. Copyright © 2012 Elsevier Inc. All rights reserved.

  11. The effects of physical exercise with music on cognitive function of elderly people: Mihama-Kiho project.

    PubMed

    Satoh, Masayuki; Ogawa, Jun-ichi; Tokita, Tomoko; Nakaguchi, Noriko; Nakao, Koji; Kida, Hirotaka; Tomimoto, Hidekazu

    2014-01-01

    Physical exercise has positive effects on cognitive function in elderly people. It is unknown, however, if combinations of non-pharmaceutical interventions can produce more benefits than single ones. This study aimed to identify if physical exercise combined with music improves cognitive function in normal elderly people more than exercise alone. We enrolled 119 subjects (age 65-84 years old). Forty subjects performed physical exercise (once a week for an hour with professional trainers) with musical accompaniment (ExM group), developed by YAMAHA Music Foundation; 40 subjects performed the same exercise without music (Ex group); 39 subjects were the control group (Cont group). Before and after the year-long intervention, each patient was assessed by neuropsychological batteries. MRIs were performed before and after intervention; the Voxel-based Specific Regional analysis system for Alzheimer's Disease (VSRAD) was used to assess medial temporal lobe atrophy. Analysis of variance (ANOVA) was significant only in visuospatial function. The multiple comparison (ExM vs. Ex, ExM vs. Cont, Ex vs. Cont) was significant between the ExM and Cont group. Intra-group analyses before and after intervention revealed significant improvement in visuospatial function in the ExM group, and significant improvements in other batteries in all three groups. The VSRAD score significantly worsened in the ExM and Ex groups. Physical exercise combined with music produced more positive effects on cognitive function in elderly people than exercise alone. We attributed this improvement to the multifaceted nature of combining physical exercise with music, which can act simultaneously as both cognitive and physical training. UMIN Clinical Trials Registry (UMIN-CTR) UMIN000012148.

  12. The Effects of Physical Exercise with Music on Cognitive Function of Elderly People: Mihama-Kiho Project

    PubMed Central

    Satoh, Masayuki; Ogawa, Jun-ichi; Tokita, Tomoko; Nakaguchi, Noriko; Nakao, Koji; Kida, Hirotaka; Tomimoto, Hidekazu

    2014-01-01

    Background Physical exercise has positive effects on cognitive function in elderly people. It is unknown, however, if combinations of non-pharmaceutical interventions can produce more benefits than single ones. This study aimed to identify if physical exercise combined with music improves cognitive function in normal elderly people more than exercise alone. Methods We enrolled 119 subjects (age 65–84 years old). Forty subjects performed physical exercise (once a week for an hour with professional trainers) with musical accompaniment (ExM group), developed by YAMAHA Music Foundation; 40 subjects performed the same exercise without music (Ex group); 39 subjects were the control group (Cont group). Before and after the year-long intervention, each patient was assessed by neuropsychological batteries. MRIs were performed before and after intervention; the Voxel-based Specific Regional analysis system for Alzheimer's Disease (VSRAD) was used to assess medial temporal lobe atrophy. Results Analysis of variance (ANOVA) was significant only in visuospatial function. The multiple comparison (ExM vs. Ex, ExM vs. Cont, Ex vs. Cont) was significant between the ExM and Cont group. Intra-group analyses before and after intervention revealed significant improvement in visuospatial function in the ExM group, and significant improvements in other batteries in all three groups. The VSRAD score significantly worsened in the ExM and Ex groups. Conclusions Physical exercise combined with music produced more positive effects on cognitive function in elderly people than exercise alone. We attributed this improvement to the multifaceted nature of combining physical exercise with music, which can act simultaneously as both cognitive and physical training. Trial Registration UMIN Clinical Trials Registry (UMIN-CTR) UMIN000012148 PMID:24769624

  13. Effect of Ganoderma lucidum (Reishi mushroom) or Olea europaea (olive) leaves on oxidative stability of rabbit meat fortified with n-3 fatty acids.

    PubMed

    Trebušak, Tina; Levart, Alenka; Salobir, Janez; Pirman, Tatjana

    2014-03-01

    The objective of the present study was to evaluate the effect of Ganoderma lucidum (Reishi mushroom) or Olea europaea (olive tree) leaves on oxidative stability of rabbit meat fortified with n-3 fatty acids. Forty-eight slovenska kunka (SIKA) rabbits were divided into four homogeneous groups. The control group (CONT-) received diet with 6% palm fat; other groups received diet with 6% linseed oil and were either unsupplemented (CONT+) or supplemented with 1% of G. lucidum (REISHI) or O. europaea leaves (OLIVE). Rabbits were slaughtered and fatty acid composition, concentration of vitamin E and malondialdehyde (MDA) in back muscle were analyzed. The results showed that linseed oil addition improved fatty acid composition by increasing polyunsaturated fatty acid (PUFA) proportion, decreasing proportion of saturated fatty acid (SFA) and reducing n-6/n-3 ratio in rabbit meat. Groups that were supplemented with linseed oil had lower content of α-tocopherol and higher content of γ-tocopherol, compared to the CONT- group. The addition of potential antioxidants did not effectively prevent oxidation of rabbit meat. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Levels of processing and the coding of position cues in motor short-term memory.

    PubMed

    Ho, L; Shea, J B

    1978-06-01

    The present study investigated the appropriateness of the levels-of-processing framework of memory for explaining retention of information in motor short-term memory. Subjects were given labels descriptive of the positions to be remembered by the experimenter (EL), were given no labels (NL), or provided their own labels (SL). A control group (CONT) was required to count backwards during the presentation of the criterion positions. The inclusion of a 30-sec filled retention interval as well as 0-sec and 30-sec unfilled retention intervals tested a prediction by Craik and Lockhart (1972), when attention is diverted from an item, information will be lost at a rate appropriate to its level of processing - that is, slower rates for deeper levels. Groups EL and SL had greater accuracy at recall for all three retention intervals than groups CONT and NL. In addition, there was no significant increase in error between 30-sec unfilled and 30-sec filled intervals for groups EL and SL, while there was a significant increase in error for groups CONT and NL. The data were interpreted in terms of Craik and Lockhart's (1972) levels-of-processing approach to memory.

  15. Continuous and interval training programs using deep water running improves functional fitness and blood pressure in the older adults.

    PubMed

    Reichert, Thaís; Kanitz, Ana Carolina; Delevatti, Rodrigo Sudatti; Bagatini, Natália Carvalho; Barroso, Bruna Machado; Kruel, Luiz Fernando Martins

    2016-02-01

    This study aimed to investigate the effects of two periodized training programs of deep water running on functional fitness and blood pressure in the older adults. Thirty-six individuals were divided into continuous group (CONT) and interval group (INT). Both groups were trained for 28 weeks (twice weekly). Measures were performed before the training period, after 12 weeks and training period. Two-way ANOVA and post hoc of Bonferroni were used (α = 0.05). There were no differences between groups in functional tests, with the exception of the flexibility of the upper limbs, in which the INT group showed the highest values. There was a significant improvement in both groups of foot up-and-go test (CONT 6.45 to 5.67; INT 6.59 to 5.78, in seconds), flexibility of lower limbs (CONT -4.76 to -0.61; INT 0.54 to 4.63, in centimeters), strength of upper (CONT 18.76 to 27.69; INT 18.66 to 26.58, in repetitions) and lower limbs (CONT 14.46 to 21.23; INT 14.40 to 21.58, in repetitions), and 6-min walk (CONT 567.50 to 591.16; INT 521.41 to 582.77, in meters). No differences were shown between groups for systolic blood pressure; however, diastolic blood pressure remained higher in CONT during all training. The blood pressure decreased significantly in both groups after the training (CONT 142 ± 16/88 ± 3 to 125 ± 14/77 ± 7 mmHg; INT 133 ± 15/75 ± 7 to 123 ± 17 and 69 ± 11 mmHg). Both programs of deep water running training promoted improvements of similar magnitude in all parameters of functional fitness, with the exception of flexibility of upper limbs, and decreased blood pressure in the older individuals.

  16. Lipolytic signaling in response to acute exercise is altered in female mice following ovariectomy

    PubMed Central

    Wohlers, Lindsay M.; Jackson, Kathryn C.; Spangenburg, Espen E.

    2011-01-01

    Impaired ovarian function alters lipid metabolism, ultimately resulting in increased visceral fat mass. Currently, we have a poor understanding of alterations in signaling events regulating lipolysis after ovarian function declines. The purpose of this study was to determine if cellular mechanisms regulating lipolysis are altered in mice after ovariectomy (OVX) and if OVX mice exhibit impaired lipolytic signaling when stimulated by acute exercise. SHAM and OVX mice were divided into two groups: control (SHAM cont; OVX cont) or acute treadmill exercise (SHAM ex; OVX ex). The omental/mesenteric (O/M) fat mass of all OVX mice was significantly greater than the SHAM mice. Serum glycerol and blood glucose levels were significantly elevated in OVX cont compared to SHAM cont. Treadmill exercise increased serum glycerol levels only in SHAM mice, with no exercise-induced change detected in OVX mice. NEFA levels were significantly elevated by acute exercise in the SHAM and OVX groups. In O/M fat from both OVX groups there were significant increases in cytosolic ATGL and PLIN2 in the fat cake fraction with concurrent reductions in PLIN1 in the fat cake compared to SHAM. Further, exercise induced significant increases in HSL Ser660 phosphorylation in SHAM mice, but not OVX mice. This suggests that reduced ovarian function has significant effects on critical lipolytic cell signaling mechanisms in O/M adipose tissue. PMID:21815195

  17. Effect of prenatal temperature conditioning of laying hen embryos: Hatching, live performance and response to heat and cold stress during laying period.

    PubMed

    Kamanli, S; Durmuş, I; Yalçın, S; Yıldırım, U; Meral, Ö

    2015-07-01

    This study was designed to determine the effect of prenatal temperature conditioning on hatching and live performance of laying chickens, and response to heat and cold stress during laying period. A total of 3600 eggs obtained from ATAK-S brown parent stock were incubated at control (37.5°C, CONT-Inc), cyclic low (36.5°C/6h/d from 10 to 18d of incubation, LOW-Inc) or high (38.5°C/6h/d from 10-18d of incubation, HIGH-Inc) incubation temperatures. Hatched chicks per incubation temperature were reared under standard rearing conditions up to 26wk. From 27 to 30wk, hens from each incubation temperature were divided into 3 environmentally controlled rooms and reared at control (20±2°C, CONT-Room), low (12±2°C, COLDS) or high (32±2°C, HEATS) temperatures. Hatching performance, body weight, egg production, and plasma triiodothyronine (T3) and thyroxine (T4) levels and oxidant and antioxidant activities were evaluated. The highest hatchability was for LOW-Inc chicks while HIGH-Inc chick had similar hatchability to CONT-Inc. There was no effect of incubation temperatures on plasma MDA, GSH-Px, activities and T4 concentrations on day of hatch. LOW- Inc chicks had higher SOD activities and T3 concentrations compared to the other groups. Although chick weight was similar among incubation temperature groups, CONT-Inc chicks were heavier than those cyclic incubation temperature groups until 12wk of age. Incubation temperature had no effect on sexual maturity age and weight and egg production of laying hens. From 27 to 30wk, regardless of incubation temperature, HEATS hens lost weight from day 0 to 10, had the highest cloacal temperatures and lowest feed consumption and egg production while COLDS hens had the lowest cloacal temperatures. At day 5, T4 level was higher in LOW-Inc hens at COLDS but it was higher in HIGH-Inc hens at HEATS compared to CONT-Inc. These data may suggest a modification in thyroid activity of hens that were conditioned during the incubation period. Moreover under COLDS condition, SOD production of LOW-Inc hens was higher than those of CONT- and HIGH-Inc hens indicating an induction in antioxidant enzyme activity. Nonetheless, prenatal temperature conditioning of laying hen embryos had no advantage on laying performance of hens under temperature stress conditions. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Clinical outcomes of ABO- and HLA-incompatible kidney transplantation: a nationwide cohort study.

    PubMed

    Ko, Eun Jeong; Yu, Ji Hyun; Yang, Chul Woo; Chung, Byung Ha

    2017-12-01

    This was a nationwide cohort study to investigate the impact of anti-A/B and donor-specific anti-HLA (HLA-DSA) antibodies on the clinical outcomes in kidney transplant recipients (KTRs). We classified a total of 1964 KTRs into four groups: transplants from ABO-incompatible donors (ABOi, n = 248); transplants in recipients with HLA-DSA (HLAi, n = 144); transplants from combined ABOi and HLAi donors (ABOi + HLAi, n = 31); and a control group for whom neither ABOi nor HLAi was applicable (CONT, n = 1541). We compared the incidence of biopsy-proven acute rejection (BPAR), allograft and patient survival rates. The incidence of BPAR was higher in the HLAi and ABOi + HLAi groups relative to the CONT group; in contrast, it was not higher in the ABOi group. Death-censored graft survival rates did not differ across the four groups. However, relative to the CONT group, patient survival rate was reduced in the ABOi and ABOi + HLAi groups, and with infection being the most common cause of death. Further, multivariable analysis revealed that desensitization therapy because of ABOi or HLAi was independent risk factors for patient mortality. HLAi was a more important risk factor for BPAR compared with ABOi. However, pretransplant desensitization therapy for either ABOi or HLAi significantly increased the risk of infection-related mortality. © 2017 Steunstichting ESOT.

  19. Proton Magnetic Resonance Spectroscopy Study on the Metabolism Changes of Cerebellum in Patients with Post-Stroke Depression.

    PubMed

    Zhang, Lei; Sui, Ru-Bo

    2017-01-01

    To study the metabolic changes of cerebellum by proton magnetic resonance Spectroscopy (1H-MRS) and discuss the relationships between the cerebellar changes and depression severity in patients with post-stroke depression. Data of demographic characteristics, individual history and life style of all subjects were collected. 40 patients with stroke and 20 controls were enrolled. All groups received T1WI, T2WI, DWI and 1H-MRS examination. The cerebral infarction volume and the distribution and severity of leukoaraiosis were evaluated. The ratios of NAA/Cr, Cho/Cr and Cho/NAA in the cerebellum were calculated. There were no statistical significant difference in the NAA/Cr, Cho/Cr and Cho/NAA ratios in bilateral cerebellum between CONT group and NORM group. The Cho/Cr and Cho/NAA ratios in the cerebellum contralateral to the stroke region were higher in PSD group than those in NORM and CONT groups, and the Cho/Cr and Cho/NAA ratios in the cerebellum ipsilateral to the stroke region were similar with those in NORM and CONT groups. However, there were no statistical significant difference in the NAA/Cr ratios in bilateral cerebellum among three groups. The result shows preliminarily that the cerebellum involves in the development of post-stroke depression. © 2017 The Author(s). Published by S. Karger AG, Basel.

  20. Effects of preoperative oral carbohydrate solution intake on thermoregulation.

    PubMed

    Ozer, Ayse B; Demirel, Ismail; Kavak, Burcin S; Gurbuz, Oguz; Unlu, Serap; Bayar, Mustafa K; Erhan, Ömer L

    2013-07-31

    We aimed to investigate the oral carbohydrate solution administered preoperatively on thermoregulation. The study included 40 female patients under general anesthesia. Patients were randomly divided into 2 groups: Group CONT (stopped oral implementation 8 h before the operation) and Group CHO (800ml oral carbohydrate fluid 8 h before the operation and 400ml oral carbohydrate fluid 2 h before the operation). Patients were monitored as standard and temperature probes were placed. Temperatures were recorded immediately before anesthetics induction, 5 min after the anesthetics induction, and in the post-anesthesia care unit (PACU) every 10 min. Mean skin temperature (Tsk), mean body temperature (Tb), and vasoconstriction threshold were estimated. In general, we observed a decrease in tympanic temperature and Tb following anesthetic administration in groups, and increase in Tsk, and an increase in all 3 of these levels in the recovery unit. Tympanic temperature was significantly higher at 25, 55, 65, and 95 min after induction in Group CONT compared to Group CHO (p<0.05). Tsk was found to be lower in Group CONT compared to Group CHO in almost all periods. In PACU, it was found that the tympanic temperature was higher in Group CONT compared to Group CHO at 60 min (p<0.05). Postoperative shivering score was found to be significantly higher in Group C (p<0.01). Vasoconstriction threshold was higher in Group CONT than Group CHO. Oral carbohydrate solution administered was established to have effects thought to be negative on tympanic temperature, vasoconstriction, and vasoconstriction threshold.

  1. Influence of cleaning methods on resin bonding to saliva-contaminated zirconia.

    PubMed

    Yoshida, Keiichi

    2018-02-08

    The aim of this study was to investigate the influence of different cleaning methods on the shear bond strengths of 2 resin cements to saliva-contaminated zirconia. After saliva contamination, alumina-blasted zirconia specimens were cleaned with 1 of 5 methods of water-rinsing (SA), K-etchant GEL phosphoric acid (PA), Ivoclean (IC), AD Gel (ADG), or additional alumina-blasting (AB). Alumina-blasted zirconia without saliva contamination was used as control group (Cont). Composite cylinders were bonded to the zirconia with 1 of 2 dual-cured resin cements. The bond strengths were measured by shear testing after 24 hours (TC0) and after thermal cycling at 4°C-60°C (TC10 000) and specimen surfaces were evaluated using X-ray photoelectron spectroscopy (XPS). Data were statistically analyzed using 3-way analysis of variance and Tukey test (α = 0.05). There were no significant differences in the bond strengths of 2 resin cements between the Cont ADG, and AB groups before and after TCs (P > .05). SA, PA, and IC groups did not exhibit durable resin bonding to zirconia. XPS showed that carbon and nitrogen increased in the SA group in comparison to the Cont group. The concentration of carbon in other 4 groups returned to the concentration range of the Cont group; however, nitrogen was not detected in the only AB group. Saliva contamination significantly reduced the bond strength of 2 resin cements to zirconia. Additional AB or cleaning with ADG resulted in effective cleaning of saliva contamination and preserved resin cement bond strength to zirconia. Saliva contamination occurs during clinical procedures for adjustment of zirconia ceramic restorations in the oral environment. AD Gel application is effective for removing saliva contaminants on the alumina-blasted zirconia surface beforehand by the dental laboratory instead of additional AB since AD Gel application and AB had a similar effect on the removal of organic components of saliva. © 2018 Wiley Periodicals, Inc.

  2. Effects of In Ovo feeding of dextrin-iodinated casein in broilers: I. Hatch weights and early growth performance.

    PubMed

    Abousaad, S; Lassiter, K; Piekarski, A; Chary, P; Striplin, K; Christensen, K; Bielke, L R; Hargis, B M; Dridi, S; Bottje, W G

    2017-05-01

    This study was conducted to determine the effect of in ovo feeding of dextrin (Dext) and iodinated casein (IC) on hatch and early growth in broilers. Three experiments were conducted at a commercial hatchery using a commercial Inovoject™ system with treatments occurring in conjunction with vaccination at transfer from incubator to hatcher units (18.5 to 19 d embryonic development). In all 3 experiments, approximately 15,000 eggs (2,500 eggs per group) were treated and transferred to a single hatcher unit. Treatments in Exp. 1 consisted of buffered saline solution alone (Control, Cont) or a dextrin solution (Dext, 18% maltodextrin, 10% potato starch dextrin) containing zero, 80, 240, 720, or 2,160 μg IC/mL. The results of this initial experiment indicated that broiler chicks at hatch that received 240 and 720 μg IC/mL in Dext were heavier (P < 0.05) compared to the other treatment groups; there were no differences in hatchability between groups. Based on these findings, subsequent studies used treatments of zero, 240, and 480 μg/mL IC in Dext or Cont. In Exp. 2, hatch weights in all treatment groups were higher (P < 0.05) compared to those receiving Cont. In Exp. 3, chicks given Dext alone or 240 and 480 μg/mL in saline weighed less at hatch compared to the other treatment groups. However, chicks provided Dext alone in Exp. 3 had less weight loss after a 24-hour holding period compared to the other groups. All treatment groups exhibited greater weight gain from one to 10 d compared to the Cont group. The results indicate that in ovo feeding of broiler embryos with Dext containing 240 and 480 μg IC/mL may have beneficial effects on broiler hatch weights and early growth rate. © 2016 Poultry Science Association Inc.

  3. Desflurane inhalation before ischemia increases ischemia-reperfusion-induced vascular leakage in isolated rabbit lungs.

    PubMed

    Oshima, Yoshiaki; Sakamoto, Seiji; Yamasaki, Kazumasa; Mochida, Shinsuke; Funaki, Kazumi; Moriyama, Naoki; Otsuki, Akihiro; Endo, Ryo; Nakasone, Masato; Takahashi, Shunsaku; Harada, Tomomi; Minami, Yukari; Inagaki, Yoshimi

    2016-01-01

    Isoflurane and sevoflurane protect lungs with ischemia-reperfusion (IR) injury. We examined the influence of desflurane on IR lung injury using isolated rabbit lungs perfused with a physiological salt solution. The isolated lungs were divided into three groups: IR, desflurane-treated ischemia-reperfusion (DES-IR), and ventilation/perfusion-continued control (Cont) groups (n = 6 per group). In the DES-IR group, inhalation of desflurane at 1 minimum alveolar concentration (MAC) was conducted in a stable 30-min phase. In the IR and DES-IR groups, ventilation/perfusion was stopped for 75 min after the stable phase. Subsequently, they were resumed. Each lung was placed on a balance, and weighed. Weight changes were measured serially throughout this experiment. The coefficient of filtration (K fc ) was determined immediately before ischemia and 60 min after reperfusion. Furthermore, bronchoalveolar lavage fluid (BALF) was collected from the right bronchus at the completion of the experiment. After the completion of the experiment, the left lung was dried, and the lung wet-to-dry weight ratio (W/D) was calculated. The K fc values at 60 min after perfusion were 0.40 ± 0.13 ml/min/mmHg/100 g in the DES-IR group, 0.26 ± 0.07 ml/min/mmHg/100 g in the IR group, and 0.22 ± 0.08 (mean ± SD) ml/mmHg/100 g in the Cont group. In the DES-IR group, the K fc at 60 min after the start of reperfusion was significantly higher than in the other groups. In the DES-IR group, W/D was significantly higher than in the Cont group. In the DES-IR group, the BALF concentrations of nitric oxide metabolites were significantly higher than in the other groups. In the DES-IR group, the total amount of vascular endothelial growth factor in BALF was significantly higher than in the Cont group. The pre-inhalation of desflurane at 1 MAC exacerbates pulmonary IR injury in isolated/perfused rabbit lungs.

  4. Memory for emotional images differs according to the presence of depressive symptoms in individuals at risk for dementia.

    PubMed

    Callahan, Brandy L; Laforce, Robert; Dugas, Michel; Hudon, Carol

    2017-04-01

    Studies of amnestic mild cognitive impairment (aMCI) and late-life depression (LLD) have examined the similarities and differences between these syndromes, but few have investigated how the cognitive profile of comorbid aMCI and subclinical depressive symptoms (aMCI/D+) may compare to that of aMCI or LLD. Memory biases for certain types of emotional information may distinguish these groups. A total of 35 aMCI, 23 aMCI/D+, 13 LLD, and 17 elderly controls (CONT) rated the valence (positive, negative, or neutral) of 30 pictures from the International Affective Picture System. Mean percent positive, negative, and neutral images recalled was compared within groups immediately and 30 minutes later. Overall memory performance was comparable in aMCI and aMCI/D+, and both recalled fewer items than CONT and LLD. Group differences emerged when valence ratings were considered: at immediate and delayed recall, positive and negative pictures were generally better-remembered than neutral pictures by CONT, aMCI, and LLD, but valence was not associated with recall in aMCI/D+. Follow-up analyses suggested that the perceived intensity of stimuli may explain the emotional enhancement effect in CONT, aMCI, and LLD. Results support previous research suggesting that the neuropsychological profile of aMCI/D+ is different from that of aMCI and LLD. Although depressed and non-depressed individuals with aMCI recall comparable quantities of information, the quality of the recalled information differs significantly. On theoretical grounds, this suggests the existence of distinct neurobiological or neurofunctional manifestations in both groups. Practically, these differences may guide the development of personalized emotion-focused encoding strategies in cognitive training programs.

  5. Effects of air-pulsed cryotherapy on neuromuscular recovery subsequent to exercise-induced muscle damage.

    PubMed

    Guilhem, Gaël; Hug, François; Couturier, Antoine; Regnault, Stéphanie; Bournat, Laure; Filliard, Jean-Robert; Dorel, Sylvain

    2013-08-01

    Localized cooling has been proposed as an effective strategy to limit the deleterious effects of exercise-induced muscle damage on neuromuscular function. However, the literature reports conflicting results. This randomized controlled trial aimed to determine the effects of a new treatment, localized air-pulsed cryotherapy (-30°C), on the recovery time-course of neuromuscular function following a strenuous eccentric exercise. Controlled laboratory study. A total of 24 participants were included in either a control group (CONT) or a cryotherapy group (CRYO). Immediately after 3 sets of 20 maximal isokinetic eccentric contractions of elbow flexors, and then 1, 2, and 3 days after exercise, the CRYO group received a cryotherapy treatment (3 × 4 minutes at -30°C separated by 1 minute). The day before and 1, 2, 3, 7, and 14 days after exercise, several parameters were quantified: maximal isometric torque and its associated maximal electromyographic activity recorded by a 64-channel electrode, delayed-onset muscle soreness (DOMS), biceps brachii transverse relaxation time (T2) measured using magnetic resonance imaging, creatine kinase activity, interleukin-6, and C-reactive protein. Maximal isometric torque decreased similarly for the CONT (-33% ± 4%) and CRYO groups (-31% ± 6%). No intergroup differences were found for DOMS, electromyographic activity, creatine kinase activity, and T2 level averaged across the whole biceps brachii. C-reactive protein significantly increased for CONT (+93% at 72 hours, P < .05) but not for CRYO. Spatial analysis showed that cryotherapy delayed the significant increase of T2 and the decrease of electromyographic activity level for CRYO compared with CONT (between day 1 and day 3) in the medio-distal part of the biceps brachii. Although some indicators of muscle damage after severe eccentric exercise were delayed (ie, local formation of edema and decrease of muscle activity) by repeated air-pulsed cryotherapy, we provide evidence that this cooling procedure failed to improve long-term recovery of muscle performance. Four applications of air-pulsed cryotherapy in the 3 days after a strenuous eccentric exercise are ineffective overall in promoting long-term muscle recovery. Further studies taking into account the amount of exercise-induced muscle damage would allow investigators to make stronger conclusions regarding the inefficiency of this recovery modality.

  6. Effects of dietary betaine on growth performance, fat deposition and serum lipids in broilers subjected to chronic heat stress.

    PubMed

    He, Shaojun; Zhao, Shujing; Dai, Sifa; Liu, Deyi; Bokhari, Shehla Gul

    2015-10-01

    We evaluated the effects of supplementing betaine on growth performance, fat deposition and lipid metabolism status in broilers kept under chronic heat stress. Five hundred and forty chicks were randomly divided into six groups and the two normal temperature groups were held at normal ambient temperature and fed the basal diet (CONT) and basal diet plus 0.1% betaine, respectively. Heat stressed (HS) broilers were held at 32 ± 1°C from days 22 to 42 and fed the basal diet containing variable levels of betaine. Broilers were examined at days 28, 35 and 42 for body weight, feed consumption, fat deposition and serum lipids. The CONT and betaine-supplemented groups showed higher (P < 0.01 or P < 0.05) feed consumption, body weight gain, and lower feed : gain ratio compared with the HS-CONT group. Meanwhile, heat stress increased abdominal, intermuscular and subcutaneous fat deposition, whereas the supplemental betaine significantly decreased those compared with the HS-CONT group. Additionally, betaine supplementation significantly decreased triglyceride, free fatty acids, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol compared with HS-CONT. Chronic HS reduces broiler production performance. However, betaine can reverse these negative effects partially and thus improve carcass composition by changing lipid metabolism. © 2015 Japanese Society of Animal Science.

  7. Neurophysiological study on the effect of various short durations of deep breathing: A randomized controlled trial.

    PubMed

    Cheng, Kok Suen; Han, Ray P S; Lee, Poh Foong

    2018-02-01

    The study aims to study the effects of short duration deep breathing on the EEG power with topography based on parallel group randomized controlled trial design which was lacking in prior reports. 50 participants were split into 4 groups: control (CONT), deep breathing (DB) for 5 (DB5), 7 (DB7), and 9 (DB9) minutes. EEG recordings were obtained during baseline, deep breathing session, after deep breathing, and a follow-up session after 7 days of consecutive practice. Frontal theta power of DB5 and DB9 was significantly larger than that of CONT after the deep breathing session (p = 0.027 and p = 0.006, respectively) and the profound finding showed that the theta topography obtained a central-focused distribution for DB7 and DB9. The result obtained was consistent with previous literature, albeit for certain deep breathing durations only, indicating a possible linkage between the deep breathing duration and the neurophysiology of the brain. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Microvascular oxygen partial pressure during hyperbaric oxygen in diabetic rat skeletal muscle.

    PubMed

    Yamakoshi, Kohei; Yagishita, Kazuyoshi; Tsuchimochi, Hirotsugu; Inagaki, Tadakatsu; Shirai, Mikiyasu; Poole, David C; Kano, Yutaka

    2015-12-15

    Hyperbaric oxygen (HBO) is a major therapeutic treatment for ischemic ulcerations that perforate skin and underlying muscle in diabetic patients. These lesions do not heal effectively, in part, because of the hypoxic microvascular O2 partial pressures (PmvO2 ) resulting from diabetes-induced cardiovascular dysfunction, which alters the dynamic balance between O2 delivery (Q̇o2) and utilization (V̇o2) rates. We tested the hypothesis that HBO in diabetic muscle would exacerbate the hyperoxic PmvO2 dynamics due, in part, to a reduction or slowing of the cardiovascular, sympathetic nervous, and respiratory system responses to acute HBO exposure. Adult male Wistar rats were divided randomly into diabetic (DIA: streptozotocin ip) and healthy (control) groups. A small animal hyperbaric chamber was pressurized with oxygen (100% O2) to 3.0 atmospheres absolute (ATA) at 0.2 ATA/min. Phosphorescence quenching techniques were used to measure PmvO2 in tibialis anterior muscle of anesthetized rats during HBO. Lumbar sympathetic nerve activity (LSNA), heart rate (HR), and respiratory rate (RR) were measured electrophysiologically. During the normobaric hyperoxia and HBO, DIA tibialis anterior PmvO2 increased faster (mean response time, CONT 78 ± 8, DIA 55 ± 8 s, P < 0.05) than CONT. Subsequently, PmvO2 remained elevated at similar levels in CONT and DIA muscles until normobaric normoxic recovery where the DIA PmvO2 retained its hyperoxic level longer than CONT. Sympathetic nervous system and cardiac and respiratory responses to HBO were slower in DIA vs. CONT. Specifically the mean response times for RR (CONT: 6 ± 1 s, DIA: 29 ± 4 s, P < 0.05), HR (CONT: 16 ± 1 s, DIA: 45 ± 5 s, P < 0.05), and LSNA (CONT: 140 ± 16 s, DIA: 247 ± 34 s, P < 0.05) were greater following HBO onset in DIA than CONT. HBO treatment increases tibialis anterior muscle PmvO2 more rapidly and for a longer duration in DIA than CONT, but not to a greater level. Whereas respiratory, cardiovascular, and LSNA responses to HBO are profoundly slowed in DIA, only the cardiovascular arm (via HR) may contribute to the muscle vascular incompetence and these faster PmvO2 kinetics. Copyright © 2015 the American Physiological Society.

  9. Effects of a Proteasome Inhibitor on Cardiomyocytes in a Pressure-Overload Hypertrophy Rat Model: An Animal Study.

    PubMed

    Kim, In-Sub; Jo, Won-Min

    2017-06-01

    The ubiquitin-proteasome system (UPS) is an important pathway of proteolysis in pathologic hypertrophic cardiomyocytes. We hypothesize that MG132, a proteasome inhibitor, might prevent hypertrophic cardiomyopathy (CMP) by blocking the UPS. Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and androgen receptor (AR) have been reported to be mediators of CMP and heart failure. This study drew upon pathophysiologic studies and the analysis of NF-κB and AR to assess the cardioprotective effects of MG132 in a left ventricular hypertrophy (LVH) rat model. We constructed a transverse aortic constriction (TAC)-induced LVH rat model with 3 groups: sham (TAC-sham, n=10), control (TAC-cont, n=10), and MG132 administration (TAC-MG132, n=10). MG-132 (0.1 mg/kg) was injected for 4 weeks in the TAC-MG132 group. Pathophysiologic evaluations were performed and the expression of AR and NF-κB was measured in the left ventricle. Fibrosis was prevalent in the pathologic examination of the TAC-cont model, and it was reduced in the TAC-MG132 group, although not significantly. Less expression of AR, but not NF-κB, was found in the TAC-MG132 group than in the TAC-cont group (p<0.05). MG-132 was found to suppress AR in the TAC-CMP model by blocking the UPS, which reduced fibrosis. However, NF-κB expression levels were not related to UPS function.

  10. Neurobehavioral Deficits in a Rat Model of Recurrent Neonatal Seizures Are Prevented by a Ketogenic Diet and Correlate with Hippocampal Zinc/Lipid Transporter Signals.

    PubMed

    Tian, Tian; Ni, Hong; Sun, Bao-liang

    2015-10-01

    The ketogenic diet (KD) has been shown to be effective as an antiepileptic therapy in adults, but it has not been extensively tested for its efficacy in neonatal seizure-induced brain damage. We have previously shown altered expression of zinc/lipid metabolism-related genes in hippocampus following penicillin-induced developmental model of epilepsy. In this study, we further investigated the effect of KD on the neurobehavioral and cognitive deficits, as well as if KD has any influence in the activity of zinc/lipid transporters such as zinc transporter 3 (ZnT-3), MT-3, ApoE, ApoJ (clusterin), and ACAT-1 activities in neonatal rats submitted to flurothyl-induced recurrent seizures. Postnatal day 9 (P9), 48 Sprague-Dawley rats were randomly assigned to two groups: flurothyl-induced recurrent seizure group (EXP) and control group (CONT). On P28, they were further randomly divided into the seizure group without ketogenic diet (EXP1), seizure plus ketogenic diet (EXP2), the control group without ketogenic diet (CONT1), and the control plus ketogenic diet (CONT2). Neurological behavioral parameters of brain damage (plane righting reflex, cliff avoidance reflex, and open field test) were observed from P35 to P49. Morris water maze test was performed during P51-P57. Then hippocampal mossy fiber sprouting and the protein levels of ZnT3, MT3, ApoE, CLU, and ACAT-1 were detected by Timm staining and Western blot analysis, respectively. Flurothyl-induced neurobehavioral toxicology and aberrant mossy fiber sprouting were blocked by KD. In parallel with these behavioral changes, rats treated with KD (EXP2) showed a significant down-regulated expression of ZnT-3, MT-3, ApoE, clusterin, and ACAT-1 in hippocampus when compared with the non-KD-treated EXP1 group. Our findings provide support for zinc/lipid transporter signals being potential targets for the treatment of neonatal seizure-induced brain damage by KD.

  11. c-Myc Alters Substrate Utilization and O-GlcNAc Protein Posttranslational Modifications without Altering Cardiac Function during Early Aortic Constriction

    PubMed Central

    Ledee, Dolena; Smith, Lincoln; Bruce, Margaret; Kajimoto, Masaki; Isern, Nancy; Portman, Michael A.; Olson, Aaron K.

    2015-01-01

    Hypertrophic stimuli cause transcription of the proto-oncogene c-Myc (Myc). Prior work showed that myocardial knockout of c-Myc (Myc) attenuated hypertrophy and decreased expression of metabolic genes after aortic constriction. Accordingly, we assessed the interplay between Myc, substrate oxidation and cardiac function during early pressure overload hypertrophy. Mice with cardiac specific, inducible Myc knockout (MycKO-TAC) and non-transgenic littermates (Cont-TAC) were subjected to transverse aortic constriction (TAC; n = 7/group). Additional groups underwent sham surgery (Cont-Sham and MycKO-Sham, n = 5 per group). After two weeks, function was measured in isolated working hearts along with substrate fractional contributions to the citric acid cycle by using perfusate with 13C labeled mixed fatty acids, lactate, ketone bodies and unlabeled glucose and insulin. Cardiac function was similar between groups after TAC although +dP/dT and -dP/dT trended towards improvement in MycKO-TAC versus Cont-TAC. In sham hearts, Myc knockout did not affect cardiac function or substrate preferences for the citric acid cycle. However, Myc knockout altered fractional contributions during TAC. The unlabeled fractional contribution increased in MycKO-TAC versus Cont-TAC, whereas ketone and free fatty acid fractional contributions decreased. Additionally, protein posttranslational modifications by O-GlcNAc were significantly greater in Cont-TAC versus both Cont-Sham and MycKO-TAC. In conclusion, Myc alters substrate preferences for the citric acid cycle during early pressure overload hypertrophy without negatively affecting cardiac function. Myc also affects protein posttranslational modifications by O-GlcNAc during hypertrophy, which may regulate Myc-induced metabolic changes. PMID:26266538

  12. Changes of Serum Calcium Concentration, Frequency of Ruminal Contraction and Feed Intake Soon after Parturition of Dairy Cows Fed Difructose Anhydride III.

    PubMed

    Wynn, S; Teramura, M; Sato, T; Hanada, M

    2015-01-01

    Requirements to control the large decrease in serum calcium (Ca) due to parturition and to increase the feed intake soon after parturition have been well accepted in dairy cows. This study was aimed to investigate the feed intake affected by serum Ca concentration with difructose anhydride (DFA) III supplement in dairy cows soon after parturition. Fourteen transition Holstein cows were divided into DFA and control (CONT) groups within 1 to 5 parity variations in each group. Measurement schedule for an individual cow was from 14 d before parturition to 7 d following parturition. The cows in DFA group were supplied 0.2 kg/head/d of DFA III feed containing 40 g of pure DFA III while the cows in CONT group received no DFA III. Other feeding procedures were the same for all cows in both groups. At parturition (d 0), serum Ca concentration sharply declined in both groups (p<0.05). Time interval for recovery from decreased serum Ca to its normal range (>9.0 mg/dL) tended to be faster in DFA group (12 h) than in the CONT group (48 h), but the differences were not significant. Active ruminal contraction was observed in DFA group at following parturition of d 1 (p<0.05), d 3 (p<0.05), and d 5 (p<0.01). Dry matter (DM) intake did not differ between the groups. However, positive correlations were observed between serum Ca concentration and ruminal contraction (p<0.001), and between ruminal contraction and DM intake (p<0.001) during following parturition. According to multiple regression analysis (R(2) = 0.824, p<0.001), the DM intake was positively affected by serum Ca concentration and ruminal contraction. These results suggest that feed intake soon after parturition in dairy cows can be increased by improvement of serum Ca concentration and active ruminal contraction, but DFA III supplementation in this study did not improve the lower serum Ca concentration due to parturition.

  13. Changes of Serum Calcium Concentration, Frequency of Ruminal Contraction and Feed Intake Soon after Parturition of Dairy Cows Fed Difructose Anhydride III

    PubMed Central

    Wynn, S.; Teramura, M.; Sato, T.; Hanada, M.

    2015-01-01

    Requirements to control the large decrease in serum calcium (Ca) due to parturition and to increase the feed intake soon after parturition have been well accepted in dairy cows. This study was aimed to investigate the feed intake affected by serum Ca concentration with difructose anhydride (DFA) III supplement in dairy cows soon after parturition. Fourteen transition Holstein cows were divided into DFA and control (CONT) groups within 1 to 5 parity variations in each group. Measurement schedule for an individual cow was from 14 d before parturition to 7 d following parturition. The cows in DFA group were supplied 0.2 kg/head/d of DFA III feed containing 40 g of pure DFA III while the cows in CONT group received no DFA III. Other feeding procedures were the same for all cows in both groups. At parturition (d 0), serum Ca concentration sharply declined in both groups (p<0.05). Time interval for recovery from decreased serum Ca to its normal range (>9.0 mg/dL) tended to be faster in DFA group (12 h) than in the CONT group (48 h), but the differences were not significant. Active ruminal contraction was observed in DFA group at following parturition of d 1 (p<0.05), d 3 (p<0.05), and d 5 (p<0.01). Dry matter (DM) intake did not differ between the groups. However, positive correlations were observed between serum Ca concentration and ruminal contraction (p<0.001), and between ruminal contraction and DM intake (p<0.001) during following parturition. According to multiple regression analysis (R2 = 0.824, p<0.001), the DM intake was positively affected by serum Ca concentration and ruminal contraction. These results suggest that feed intake soon after parturition in dairy cows can be increased by improvement of serum Ca concentration and active ruminal contraction, but DFA III supplementation in this study did not improve the lower serum Ca concentration due to parturition. PMID:25557676

  14. Effect of re-expansion after short-period lung collapse on pulmonary capillary permeability and pro-inflammatory cytokine gene expression in isolated rabbit lungs.

    PubMed

    Funakoshi, T; Ishibe, Y; Okazaki, N; Miura, K; Liu, R; Nagai, S; Minami, Y

    2004-04-01

    Re-expansion pulmonary oedema is a rare complication caused by rapid re-expansion of a chronically collapsed lung. Several cases of pulmonary oedema associated with one-lung ventilation (OLV) have been reported recently. Elevated levels of pro-inflammatory cytokines in pulmonary oedema fluid are suggested to play important roles in its development. Activation of cytokines after re-expansion of collapsed lung during OLV has not been thoroughly investigated. Here we investigated the effects of re-expansion of the collapsed lung on pulmonary oedema formation and pro-inflammatory cytokine expression. Lungs isolated from female white Japanese rabbits were perfused and divided into a basal (BAS) group (n=7, baseline measurement alone), a control (CONT) group (n=9, ventilated without lung collapse for 120 min) and an atelectasis (ATEL) group (n=9, lung collapsed for 55 min followed by re-expansion and ventilation for 65 min). Pulmonary vascular resistance (PVR) and the coefficient of filtration (Kfc) were measured at baseline and 60 and 120 min. At the end of perfusion, bronchoalveolar lavage fluid/plasma protein ratio (B/P), wet/dry lung weight ratio (W/D) and mRNA expressions of tumour necrosis factor (TNF)-alpha, interleukin (IL)-1beta and myeloperoxidase (MPO) were determined. TNF-alpha and IL-1beta mRNA were significantly up-regulated in lungs of the ATEL group compared with BAS and CONT, though no significant differences were noted in PVR, Kfc, B/P and W/D within and between groups. MPO increased at 120 min in CONT and ATEL groups. Pro-inflammatory cytokines were up-regulated upon re-expansion and ventilation after short-period lung collapse, though no changes were noted in pulmonary capillary permeability.

  15. Increased systolic blood pressure in rat offspring following a maternal low-protein diet is normalized by maternal dietary choline supplementation.

    PubMed

    Bai, S Y; Briggs, D I; Vickers, M H

    2012-10-01

    An adverse prenatal environment may induce long-term metabolic consequences, in particular hypertension and cardiovascular disease. A maternal low-protein (LP) diet is well known to result in increased blood pressure (BP) in offspring. Choline has been shown to have direct BP-reducing effects in humans and animals. It has been suggested that endogenous choline synthesis via phosphatidylcholine is constrained during maternal LP exposure. The present study investigates the effect of choline supplementation to mothers fed a LP diet during pregnancy on systolic BP (SBP) in offspring as measured by tail-cuff plethysmography. Wistar rats were assigned to one of three diets to be fed ad libitum throughout pregnancy: (1) control diet (CONT, 20% protein); (2) an LP diet (9% protein); and (3) LP supplemented with choline (LP + C). Dams were fed the CONT diet throughout lactation and offspring were fed the CONT diet from weaning for the remainder of the trial. At postnatal day 150, SBP and retroperitoneal fat mass was significantly increased in LP offspring compared with CONT animals and was normalized in LP + C offspring. Effects of LP + C reduction in SBP were similar in both males and females. Plasma choline and phosphatidylcholine concentrations were not different across treatment groups, but maternal choline supplementation resulted in a significant reduction in homocysteine concentrations in LP + C offspring compared with LP and CONT animals. The present trial shows for the first time that maternal supplementation with dietary choline during periods of LP exposure can normalize increased SBP and fat mass observed in offspring in later life.

  16. Evaluation of the presence of VEGF, BMP2 and CBFA1 proteins in autogenous bone graft: histometric and immunohistochemical analysis.

    PubMed

    Guskuma, Marcos Heidy; Hochuli-Vieira, Eduardo; Pereira, Flávia Priscila; Rangel-Garcia, Idelmo; Okamoto, Roberta; Okamoto, Tetuo; Filho, Osvaldo Magro

    2014-06-01

    The purpose of this study was to evaluate the expression of proteins that participate in the osteoinduction stage (VEGF, BMP2 and CBFA1) of the process of bone regeneration of defects created in rat calvariae and filled with autogenous bone block grafts. 10 adult male rats (Rattus norvegicus albinus, Wistar) were used, who received two bone defects measuring 5 mm each in the calvariae. The bone defects constituted two experimental groups (n = 10): Control Group (CONT) (defects filled with a coagulum); Graft Group (GR) (defects filled with autogenous bone removed from the contralateral defect). The animals were submitted to euthanasia at 7 and 30 days post-operatively. Quantitative analysis demonstrated significantly greater bone formation in Group GR, but the presence of the studied proteins was significantly greater in the CONT Group in both time intervals of observation. It was not possible in this study in cortical bone block groups to detect the osteoinductive proteins in a significant amount during the repair process. Copyright © 2013 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  17. Effects of supplemental lysine and methionine with zilpaterol hydrochloride on feedlot performance, carcass merit, and skeletal muscle fiber characteristics in finishing feedlot cattle.

    PubMed

    Hosford, A D; Hergenreder, J E; Kim, J K; Baggerman, J O; Ribeiro, F R B; Anderson, M J; Spivey, K S; Rounds, W; Johnson, B J

    2015-09-01

    Feeding zilpaterol hydrochloride (ZH) with ruminally protected AA was evaluated in a small-pen feeding trial. Crossbred steers ( = 180; initial BW = 366 kg) were blocked by weight and then randomly assigned to treatments (45 pens; 9 pens/treatment). Treatment groups consisted of no ZH and no AA (Cont-), ZH and no AA (Cont+), ZH and a ruminally protected lysine supplement (Lys), ZH and a ruminally protected methionine supplement (Met), and ZH and ruminally protected lysine and methionine (Lys+Met). Zilpaterol hydrochloride (8.3 mg/kg DM) was fed for the last 20 d of the finishing period with a 3-d withdrawal period. Lysine and Met were top dressed daily for the 134-d feeding trial to provide 12 or 4 g·hd·d, respectively, to the small intestine. Carcass characteristics, striploins, and prerigor muscle samples were collected following harvest at a commercial facility. Steaks from each steer were aged for 7, 14, 21, and 28 d, and Warner-Bratzler shear force (WBSF) was determined as an indicator of tenderness. Prerigor muscle samples were used for immunohistological analysis. Cattle treated with Met and Lys+Met had increased final BW ( < 0.3) and ADG ( < 0.05) compared to Cont- and Cont+. Supplementation of Lys, Met, and Lys+Met improved G:F ( < 0.05) compared to Cont- during the ZH feeding period (d 111 to 134) as well as the entire feeding period ( < 0.05). Zilpaterol hydrochloride increased carcass ADG ( < 0.05) when compared to non-ZH-fed steers. Methionine and Lys+Met treatments had heavier HCW ( < 0.02) than that of Cont-. Yield grade was decreased ( < 0.04) for Cont+ steers compared to steers treated with Lys, Lys+Met, and Cont-. Tenderness was reduced ( < 0.05) with ZH regardless of AA supplementation. Lysine, Met, Lys+Met, and Cont+ had less tender steaks ( < 0.05) throughout all aging groups compared to Cont-. Steaks from Lys-treated steers were less tender ( < 0.05) than those of Cont+ during the 7- and 14-d aging periods. Nuclei density was the greatest with Cont- cattle compared to all other treatments suggesting a dilution effect of the nuclei in the larger muscle fibers with ZH feeding. Supplementation of Met in conjunction with ZH feeding increased ADG and HCW although this may lead to decreased tenderness even after aging for 28 d. These findings indicated that steers fed ZH may require additional AA absorbed from the small intestine to maximize performance.

  18. The Monitoring of Technology Transfer to the USSR.

    DTIC Science & Technology

    1982-08-01

    nizational options for improving the present system for monitor- ing technology transfer. (Cont. on reverse side) DO ,FN 1473 EDITION OF INOV SS...imposition of military control in Poland , a further curtailment of the exchange activi- ties followed. In particular, three agreements (in existence in 1981...its own, P. Poland is also in a separate Country Group W. North Korea, Vietnam, Cambodia, and Cuba are in Country Group Z. Department of Commerce

  19. Mitigating Stress, Workload, and Fatigue on the Electronic Battlefield

    DTIC Science & Technology

    2007-03-28

    left up to graphic designers , marketers, and advertisers (Teague & Whitney, 2002). Such research relies on focus groups and samples of opinion as to...cont. • Previous Research on Menu Design – Color coding • Tullis, 1981; Yeh & Wickens 2001 – Grouping • Kahneman & Henick, 1977; Winzenz, 1972... research (Sheridan, 2002). The issue of control is a vital one since it is evident that we still design as though the machine system is to react

  20. The effect of zilpaterol hydrochloride supplementation on energy metabolism and nitrogen and carbon retention of steers fed at maintenance and fasting intake levels.

    PubMed

    Walter, L J; Cole, N A; Jennings, J S; Hutcheson, J P; Meyer, B E; Schmitz, A N; Reed, D D; Lawrence, T E

    2016-10-01

    An indirect calorimetry trial examined energy metabolism, apparent nutrient digestibility, C retention (CR), and N retention (NR) of cattle supplemented with zilpaterol hydrochloride (ZH). Beef steers ( = 20; 463 ± 14 kg) blocked ( = 5) by weight and source were individually fed and adapted to maintenance energy intake for 21 d before allotment to ZH (90 mg/steer∙d) or no β-adrenergic agonist treatment (control [CONT]) for 20 d (455 ± 14 kg at the start of treatment). Respiration chambers = 4 were used to quantify heat production (HP) during maintenance (d 12 to 16 of the ZH period) and fasting heat production (FHP; d 19 to 20 of ZH period; total 4 d of fast). Steers were harvested after a 6-d ZH withdrawal and carcasses were graded 24 h after harvest. Control cattle lost more BW ( < 0.01; 9 kg for CONT and 2 kg for ZH-treated) during maintenance whereas the BW loss of ZH-treated steers was greater ( < 0.01; 9 kg for ZH-treated and vs. 4 kg, for CONT) during FHP; no differences ( ≥ 0.76) were detected for G:F, ADG, and end BW. No differences in DMI, apparent nutrient digestibility, O consumption, or CH production ( ≥ 0.12) were detected; however, ZH-treated cattle had greater CO production during maintenance ( = 0.04; 23.6 L/kgBW for ZH-treated and 22.4 L/kg BW for CONT). Digestible energy and ME did not differ ( ≥ 0.19); however, urinary energy was greater ( = 0.05; 0.091 Mcal for CONT and 0.074 Mcal for ZH-treated) in CONT cattle. Steers treated with ZH tended to have greater HP ( = 0.09; 12.44 Mcal for ZH-treated and 11.69 Mcal for CONT), but the effect was reduced on a BW basis ( = 0.12; 0.126 Mcal/kg BW0.75 for ZH-treated and 0.120 Mcal/kg BW0.75 for CONT vs. 0.120 Mcal/kg BW). No treatment difference in FHP was observed ( ≥ 0.32) although CO production (L/steer) increased with ZH treatment ( = 0.04; 1,423 L/steer for ZH-treated and 1,338 L/steer for CONT). Control cattle excreted more ( = 0.05) N in urine (39.8 g/d for CONT and 32.4 g/d for ZH-treated); therefore, NR ( = 0.07; 22.14 g/d for ZH-treated and 14.12 g/d for CONT steers) tended to be greater for ZH-fed steers. Steers treated with ZH lost more C via CO ( = 0.04; 1,036.9 g/d for ZH-treated and 974.3 g/d for CONT) although total CR did not differ ( ≥ 0.23). Empty BW, HCW, and harvest yields (g/kg empty BW) were not different ( ≥ 0.13), whereas ZH increased dressed yield ( = 0.02; 62.12 % for ZH-treated and 60.65% for CONT) and LM area ( = 0.02; 77.81 cm for ZH-treated and vs. 70.90 cm for CONT). Separable carcass lean and actual skeletal muscle protein (SMP) were increased with ZH ( ≤ 0.04; 201.6 and 41.2 kg, respectively for ZH-treated and 196.0 and 38.4 kg, respectively for CONT). Results from this trial indicate that ZH treatment increased ( = 0.03) SMP and tended ( ≥ 0.07) to increase NR and modify HP during maintenance by increasing CO production.

  1. Catalogue of Tenebrionidae (Coleoptera) of North America.

    PubMed

    Bousquet, Yves; Thomas, Donald B; Bouchard, Patrice; Smith, Aaron D; Aalbu, Rolf L; Johnston, M Andrew; Steiner, Warren E

    2017-01-01

    This catalogue includes all valid family-group (8 subfamilies, 52 tribes, 14 subtribes), genus-group (349 genera, 86 subgenera), and species-group names (2825 species, 215 subspecies) of darkling beetles (Coleoptera: Tenebrionidae) known to occur in North America and their available synonyms. Data on extant, subfossil and fossil taxa are given. For each name the author and year and page number of the description are provided, with additional information (e.g., type species for genus-group names, author of synonymies for invalid taxa) depending on the taxon rank. Several new nomenclatural acts are included. One new genus, Lepidocnemeplatia Bousquet and Bouchard, is described. Spelaebiosis Bousquet and Bouchard [for Ardoinia Özdikmen, 2004], Blapstinus marcuzzii Aalbu [for Blapstinus kulzeri Marcuzzi, 1977], and Hymenorus campbelli Bouchard [for Hymenorus oculatus Doyen and Poinar, 1994] are proposed as new replacement names. Supporting evidence is provided for the conservation of usage of Tarpela micans (Fabricius, 1798) nomen protectum over Tarpela vittata (Olivier, 1793) nomen oblitum . The generic names Psilomera Motschulsky, 1870 [= Stenomorpha Solier, 1836], Steneleodes Blaisdell, 1909 [= Xysta Eschscholtz, 1829], Ooconibius Casey, 1895 and Euconibius Casey, 1895 [= Conibius LeConte, 1851] are new synonyms (valid names in square brackets). The following 127 new synonymies of species-group names, listed in their original combination, are proposed (valid names, in their current combination, placed in square brackets): Bothrasida mucorea Wilke, 1922 [= Pelecyphorus guanajuatensis (Champion, 1884)]; Parasida zacualpanicola Wilke, 1922 [= Pelecyphorus asidoides Solier, 1836]; Stenosides kulzeri Pallister, 1954, Stenosides bisinuatus Pallister, 1954, and Parasida trisinuata Pallister, 1954 [= Pelecyphorus dispar (Champion, 1892)]; Asida favosa Champion, 1884 and Asida similata Champion, 1884 [= Pelecyphorus fallax (Champion, 1884)]; Ologlyptus bicarinatus Champion, 1884 [= Pelecyphorus indutus (Champion, 1884)]; Parasida laciniata Casey, 1912 and Parasida cristata Pallister, 1954 [= Pelecyphorus liratus (LeConte, 1854)]; Parasida esperanzae Wilke, 1922 and Parasida mixtecae Wilke, 1922 [= Pelecyphorus longipennis (Champion, 1884)]; Parasida tolucana Casey, 1912 [= Pelecyphorus scutellaris (Champion, 1884)]; Parasida purpusi Wilke, 1922 [= Pelecyphorus tristis (Champion, 1884)]; Astrotus nosodermoides Champion, 1892 [= Pelecyphorus erosus (Champion, 1892)]; Astrotus seticornis var. humeralis Champion, 1884 [= Pelecyphorus seticornis (Champion, 1884)]; Pactostoma breviuscula Casey, 1912, Pactostoma exoleta Casey, 1912, Pactostoma luteotecta Casey, 1912, Pactostoma monticola Casey, 1912, Pactostoma obtecta Casey, 1912, and Pactostoma sigillata Casey, 1912 [= Pelecyphorus anastomosis (Say, 1824)]; Ologlyptus canus Champion, 1884 and Ologlyptus sinuaticollis Champion, 1884 [= Pelecyphorus graciliformis (Solier, 1836)]; Gonasida elata reducta Casey, 1912, Gonasida elata prolixa Casey, 1912, and Gonasida aucta Casey, 1912 [= Philolithus elatus compar (Casey, 1912)]; Gonasida alaticollis Casey, 1912 [= Philolithus elatus difformis (LeConte, 1854)]; Gonasida gravida Casey, 1912 [= Philolithus elatus elatus (LeConte, 1853)]; Pelecyphorus aegrotus limbatus Casey, 1912 [= Philolithus aegrotus aegrotus (LeConte, 1861)]; Pelecyphorus corporalis Casey, 1912, Pelecyphorus reptans Casey, 1912, Pelecyphorus socer Casey, 1912, Pelecyphorus abscissus Casey, 1912, Pelecyphorus fumosus Casey, 1912, Pelecyphorus parvus Casey, 1912, Pelecyphorus morbillosus pacatus Casey, 1912, Pelecyphorus morbillosus sobrius Casey, 1912, Pelecyphorus piceus Casey, 1912, Pelecyphorus piceus crudelis Casey, 1912, Pelecyphorus snowi Casey, 1912, and Pelecyphorus subtenuis Casey, 1912 [= Philolithus morbillosus (LeConte, 1858)]; Bothrasida sanctae-agnae Wilke, 1922 [= Stenomorpha funesta (Champion, 1884)]; Asida flaccida Horn, 1896 [= Stenomorpha embaphionides (Horn, 1894)]; Asida angustula Casey, 1890, Stethasida stricta Casey, 1912, Stethasida muricatula languida Casey, 1912, Stethasida pertinax Casey, 1912, Stethasida socors Casey, 1912, Stethasida angustula inepta Casey, 1912, Stethasida tenax Casey, 1912, and Stethasida vegrandis Casey, 1912 [= Stenomorpha muricatula (LeConte, 1851)]; Stethasida obsoleta expansa Casey, 1912, Stethasida obsoleta opacella Casey, 1912, Stethasida brevipes Casey, 1912, Stethasida torpida Casey, 1912, Stethasida convergens Casey, 1912, Stethasida discreta Casey, 1912, Stethasida longula Casey, 1912, Stethasida adumbrata Casey, 1912, Stethasida occulta Casey, 1912, Stethasida tarsalis Casey, 1912, Stethasida unica Casey, 1912, and Pelecyphorus laevigatus Papp, 1961 [= Stenomorpha obsoleta (LeConte, 1851)]; Trichiasida eremica Wilke, 1922 [= Stenomorpha difficilis (Champion, 1884)]; Trichiasida lineatopilosa Casey, 1912 [= Stenomorpha hirsuta (LeConte, 1851)]; Trichiasida tenella Casey, 1912 [= Stenomorpha hispidula (LeConte, 1851)]; Trichiasida duplex Casey, 1912 [= Stenomorpha villosa (Champion, 1884)]; Alaudes squamosa Blaisdell, 1919, Alaudes testacea Blaisdell, 1919, and Alaudes fallax Fall, 1928 [= Alaudes singularis Horn, 1870]; Edrotes barrowsi Dajoz, 1999 [= Edrotes ventricosus LeConte, 1851]; Nyctoporis tetrica Casey, 1907 and Nyctoporis maura Casey, 1907 [= Nyctoporis aequicollis Eschscholtz, 1831]; Nyctoporis pullata Casey, 1907 [= Nyctoporis sponsa Casey, 1907]; Eleodes tibialis forma oblonga Blaisdell, 1909 [= Eleodes tibialis Blaisdell, 1909]; Eleodes ( manni var.) variolosa Blaisdell, 1917 [= Eleodes constrictus LeConte, 1858]; Eleodes cordata forma sublaevis Blaisdell, 1909, Eleodes cordata forma intermedia Blaisdell, 1909, Eleodes cordata forma oblonga Blaisdell, 1909, Eleodes cordata forma elongata Blaisdell, 1909, and Eleodes ( cordata var.) adulterina Blaisdell, 1917 [= Eleodes cordata Eschscholtz, 1829]; Eleodes hornii var. monticula Blaisdell, 1918 and Eleodes manni sierra Blaisdell, 1925 [= Eleodes fuchsii Blaisdell, 1909]; Eleodes parvicollis var. squalida Blaisdell, 1918 [= Eleodes parvicollis Eschscholtz, 1829]; Eleodes reflexicollis Mannerheim, 1843 and Eleodes parvicollis forma farallonica Blaisdell, 1909 [= Eleodes planata Eschscholtz, 1829]; Eleodes indentata Blaisdell, 1935 [= Eleodes rotundipennis LeConte, 1857]; Eleodes intricata Mannerheim, 1843 [= Eleodes scabrosa Eschscholtz, 1829]; Eleodes horni fenyesi Blaisdell, 1925 [= Eleodes tenebrosa Horn, 1870]; Eleodes cordata var. horrida Blaisdell, 1918 [= Eleodes tuberculata Eschscholtz, 1829]; Eleodes oblonga Blaisdell, 1933 [= Eleodes versatilis Blaisdell, 1921]; Eleodes dentipes marinae Blaisdell, 1921 [= Eleodes dentipes Eschscholtz, 1829]; Eleodes carbonaria forma glabra Blaisdell, 1909 [= Eleodes carbonaria carbonaria (Say, 1824)]; Eleodes granosa forma fortis Blaisdell, 1909 [= Eleodes granosa LeConte, 1866]; Eleodes pilosa forma ordinata Blaisdell, 1909 [= Eleodes pilosa Horn, 1870]; Trogloderus costatus pappi Kulzer, 1960 [= Trogloderus tuberculatus Blaisdell, 1909]; Trogloderus costatus mayhewi Papp, 1961 [= Trogloderus vandykei La Rivers, 1946]; Bolitophagus cristatus Gosse, 1840 [= Bolitotherus cornutus (Fabricius, 1801)]; Eleates explanatus Casey, 1890 [= Eleates depressus (Randall, 1838)]; Blapstinus sonorae Casey, 1890 [= Blapstinus brevicollis LeConte, 1851]; Blapstinus falli Blaisdell, 1929 [= Blapstinus castaneus Casey, 1890]; Blapstinus brunneus Casey, 1890 and Blapstinus coronadensis Blaisdell, 1892 [= Blapstinus histricus Casey, 1890]; Blapstinus hesperius Casey, 1890 [= Blapstinus intermixtus Casey, 1890]; Blapstinus cinerascens Fall, 1929 [= Blapstinus lecontei Mulsant and Rey, 1859]; Blapstinus niger Casey, 1890 and Blapstinus cribricollis Casey, 1890 [= Blapstinus pimalis Casey, 1885]; Blapstinus arenarius Casey, 1890 [= Blapstinus pratensis LeConte, 1859]; Blapstinus gregalis Casey, 1890 [= Blapstinus substriatus Champion, 1885]; Blapstinus hydropicus Casey, 1890 [= Blapstinus sulcatus LeConte, 1851]; Blapstinus hospes Casey, 1890 [= Blapstinus vestitus LeConte, 1859]; Notibius reflexus Horn, 1894 [= Conibius opacus (LeConte, 1866)]; Notibius affinis Champion, 1885 [= Conibius rugipes (Champion, 1885)]; Conibius parallelus LeConte, 1851 [= Conibius seriatus LeConte, 1851]; Nocibiotes rubripes Casey, 1895 [= Nocibiotes caudatus Casey, 1895]; Nocibiotes gracilis Casey, 1895 and Nocibiotes acutus Casey, 1895 [= Nocibiotes granulatus (LeConte, 1851)]; Conibius alternatus Casey, 1890 [= Tonibius sulcatus (LeConte, 1851)]; Pedinus suturalis Say, 1824 [= Alaetrinus minimus (Palisot de Beauvois, 1817)]; Menedrio longipennis Motschulsky, 1872 [= Tenebrio obscurus Fabricius, 1792]; Hymenophorus megops Hatch, 1965 and Telesicles magnus Hatch, 1965 [= Hymenorus sinuatus Fall, 1931]; Andrimus concolor Casey, 1891 and Andrimus convergens Casey, 1891 [= Andrimus murrayi (LeConte, 1866)]; Mycetochara marshalli Campbell, 1978 [= Mycetochara perplexata Marshall, 1970]; Phaleria globosa LeConte, 1857 [= Phaleria picta Mannerheim, 1843]. The following subspecies of Trogloderus costatus LeConte, 1879 are given species rank: Trogloderus nevadus La Rivers, 1943, Trogloderus tuberculatus Blaisdell, 1909, and Trogloderus vandykei La Rivers, 1946. The following taxa, previously thought to be junior synonyms, are considered valid: Amphidora Eschscholtz, 1829; Xysta Eschscholtz, 1829; Helops confluens (Casey, 1924). Two new combinations are proposed: Stenomorpha spinimana (Champion, 1892) and Stenomorpha tenebrosa (Champion, 1892) [from the genus Parasida Casey, 1912]. The type species [placed in square brackets] of the following 12 genus-group taxa are designated for the first time: Lagriola Kirsch, 1874 [ Lagriola operosa Kirsch, 1874]; Locrodes Casey, 1907 [ Emmenastus piceus Casey, 1890]; Falacer Laporte, 1840 [ Acanthopus cupreus Laporte, 1840 (= Helops contractus Palisot de Beauvois, 1812)]; Blapylis Horn, 1870 [ Eleodes cordata Eschscholtz, 1829]; Discogenia LeConte, 1866 [ Eleodes scabricula LeConte, 1858]; Metablapylis Blaisdell, 1909 [ Eleodes nigrina LeConte, 1858]; Steneleodes Blaisdell, 1909 [ Eleodes longicollis LeConte, 1851]; Scaptes Champion, 1886 [ Scaptes squamulatus Champion, 1886 (= Asida tropica Kirsch, 1866)]; Aspidius Mulsant and Rey, 1859 [ Blaps punctata Fabricius, 1792]; Cryptozoon Schaufuss, 1882 [ Cryptozoon civile Schaufuss, 1882]; Halophalerus Crotch, 1874 [ Phaleria rotundata LeConte, 1851]; Dignamptus LeConte, 1878 [ Dignamptus stenochinus LeConte, 1878]. Two species previously known from South America [ Nilio lebasi J. Thomson and Platydema erotyloides Chevrolat] are reported for the first time from North America.

  2. Catalogue of Tenebrionidae (Coleoptera) of North America

    PubMed Central

    Bousquet, Yves; Thomas, Donald B.; Bouchard, Patrice; Smith, Aaron D.; Aalbu, Rolf L.; Johnston, M. Andrew; Jr., Warren E. Steiner

    2018-01-01

    Abstract This catalogue includes all valid family-group (8 subfamilies, 52 tribes, 14 subtribes), genus-group (349 genera, 86 subgenera), and species-group names (2825 species, 215 subspecies) of darkling beetles (Coleoptera: Tenebrionidae) known to occur in North America1 and their available synonyms. Data on extant, subfossil and fossil taxa are given. For each name the author and year and page number of the description are provided, with additional information (e.g., type species for genus-group names, author of synonymies for invalid taxa) depending on the taxon rank. Several new nomenclatural acts are included. One new genus, Lepidocnemeplatia Bousquet and Bouchard, is described. Spelaebiosis Bousquet and Bouchard [for Ardoinia Özdikmen, 2004], Blapstinus marcuzzii Aalbu [for Blapstinus kulzeri Marcuzzi, 1977], and Hymenorus campbelli Bouchard [for Hymenorus oculatus Doyen and Poinar, 1994] are proposed as new replacement names. Supporting evidence is provided for the conservation of usage of Tarpela micans (Fabricius, 1798) nomen protectum over Tarpela vittata (Olivier, 1793) nomen oblitum. The generic names Psilomera Motschulsky, 1870 [= Stenomorpha Solier, 1836], Steneleodes Blaisdell, 1909 [= Xysta Eschscholtz, 1829], Ooconibius Casey, 1895 and Euconibius Casey, 1895 [= Conibius LeConte, 1851] are new synonyms (valid names in square brackets). The following 127 new synonymies of species-group names, listed in their original combination, are proposed (valid names, in their current combination, placed in square brackets): Bothrasida mucorea Wilke, 1922 [= Pelecyphorus guanajuatensis (Champion, 1884)]; Parasida zacualpanicola Wilke, 1922 [= Pelecyphorus asidoides Solier, 1836]; Stenosides kulzeri Pallister, 1954, Stenosides bisinuatus Pallister, 1954, and Parasida trisinuata Pallister, 1954 [= Pelecyphorus dispar (Champion, 1892)]; Asida favosa Champion, 1884 and Asida similata Champion, 1884 [= Pelecyphorus fallax (Champion, 1884)]; Ologlyptus bicarinatus Champion, 1884 [= Pelecyphorus indutus (Champion, 1884)]; Parasida laciniata Casey, 1912 and Parasida cristata Pallister, 1954 [= Pelecyphorus liratus (LeConte, 1854)]; Parasida esperanzae Wilke, 1922 and Parasida mixtecae Wilke, 1922 [= Pelecyphorus longipennis (Champion, 1884)]; Parasida tolucana Casey, 1912 [= Pelecyphorus scutellaris (Champion, 1884)]; Parasida purpusi Wilke, 1922 [= Pelecyphorus tristis (Champion, 1884)]; Astrotus nosodermoides Champion, 1892 [= Pelecyphorus erosus (Champion, 1892)]; Astrotus seticornis var. humeralis Champion, 1884 [= Pelecyphorus seticornis (Champion, 1884)]; Pactostoma breviuscula Casey, 1912, Pactostoma exoleta Casey, 1912, Pactostoma luteotecta Casey, 1912, Pactostoma monticola Casey, 1912, Pactostoma obtecta Casey, 1912, and Pactostoma sigillata Casey, 1912 [=Pelecyphorus anastomosis (Say, 1824)]; Ologlyptus canus Champion, 1884 and Ologlyptus sinuaticollis Champion, 1884 [= Pelecyphorus graciliformis (Solier, 1836)]; Gonasida elata reducta Casey, 1912, Gonasida elata prolixa Casey, 1912, and Gonasida aucta Casey, 1912 [= Philolithus elatus compar (Casey, 1912)]; Gonasida alaticollis Casey, 1912 [= Philolithus elatus difformis (LeConte, 1854)]; Gonasida gravida Casey, 1912 [= Philolithus elatus elatus (LeConte, 1853)]; Pelecyphorus aegrotus limbatus Casey, 1912 [= Philolithus aegrotus aegrotus (LeConte, 1861)]; Pelecyphorus corporalis Casey, 1912, Pelecyphorus reptans Casey, 1912, Pelecyphorus socer Casey, 1912, Pelecyphorus abscissus Casey, 1912, Pelecyphorus fumosus Casey, 1912, Pelecyphorus parvus Casey, 1912, Pelecyphorus morbillosus pacatus Casey, 1912, Pelecyphorus morbillosus sobrius Casey, 1912, Pelecyphorus piceus Casey, 1912, Pelecyphorus piceus crudelis Casey, 1912, Pelecyphorus snowi Casey, 1912, and Pelecyphorus subtenuis Casey, 1912 [= Philolithus morbillosus (LeConte, 1858)]; Bothrasida sanctae-agnae Wilke, 1922 [= Stenomorpha funesta (Champion, 1884)]; Asida flaccida Horn, 1896 [= Stenomorpha embaphionides (Horn, 1894)]; Asida angustula Casey, 1890, Stethasida stricta Casey, 1912, Stethasida muricatula languida Casey, 1912, Stethasida pertinax Casey, 1912, Stethasida socors Casey, 1912, Stethasida angustula inepta Casey, 1912, Stethasida tenax Casey, 1912, and Stethasida vegrandis Casey, 1912 [= Stenomorpha muricatula (LeConte, 1851)]; Stethasida obsoleta expansa Casey, 1912, Stethasida obsoleta opacella Casey, 1912, Stethasida brevipes Casey, 1912, Stethasida torpida Casey, 1912, Stethasida convergens Casey, 1912, Stethasida discreta Casey, 1912, Stethasida longula Casey, 1912, Stethasida adumbrata Casey, 1912, Stethasida occulta Casey, 1912, Stethasida tarsalis Casey, 1912, Stethasida unica Casey, 1912, and Pelecyphorus laevigatus Papp, 1961 [= Stenomorpha obsoleta (LeConte, 1851)]; Trichiasida eremica Wilke, 1922 [= Stenomorpha difficilis (Champion, 1884)]; Trichiasida lineatopilosa Casey, 1912 [= Stenomorpha hirsuta (LeConte, 1851)]; Trichiasida tenella Casey, 1912 [= Stenomorpha hispidula (LeConte, 1851)]; Trichiasida duplex Casey, 1912 [= Stenomorpha villosa (Champion, 1884)]; Alaudes squamosa Blaisdell, 1919, Alaudes testacea Blaisdell, 1919, and Alaudes fallax Fall, 1928 [= Alaudes singularis Horn, 1870]; Edrotes barrowsi Dajoz, 1999 [=Edrotes ventricosus LeConte, 1851]; Nyctoporis tetrica Casey, 1907 and Nyctoporis maura Casey, 1907 [= Nyctoporis aequicollis Eschscholtz, 1831]; Nyctoporis pullata Casey, 1907 [= Nyctoporis sponsa Casey, 1907]; Eleodes tibialis forma oblonga Blaisdell, 1909 [= Eleodes tibialis Blaisdell, 1909]; Eleodes (manni var.) variolosa Blaisdell, 1917 [= Eleodes constrictus LeConte, 1858]; Eleodes cordata forma sublaevis Blaisdell, 1909, Eleodes cordata forma intermedia Blaisdell, 1909, Eleodes cordata forma oblonga Blaisdell, 1909, Eleodes cordata forma elongata Blaisdell, 1909, and Eleodes (cordata var.) adulterina Blaisdell, 1917 [= Eleodes cordata Eschscholtz, 1829]; Eleodes hornii var. monticula Blaisdell, 1918 and Eleodes manni sierra Blaisdell, 1925 [= Eleodes fuchsii Blaisdell, 1909]; Eleodes parvicollis var. squalida Blaisdell, 1918 [= Eleodes parvicollis Eschscholtz, 1829]; Eleodes reflexicollis Mannerheim, 1843 and Eleodes parvicollis forma farallonica Blaisdell, 1909 [= Eleodes planata Eschscholtz, 1829]; Eleodes indentata Blaisdell, 1935 [= Eleodes rotundipennis LeConte, 1857]; Eleodes intricata Mannerheim, 1843 [= Eleodes scabrosa Eschscholtz, 1829]; Eleodes horni fenyesi Blaisdell, 1925 [= Eleodes tenebrosa Horn, 1870]; Eleodes cordata var. horrida Blaisdell, 1918 [= Eleodes tuberculata Eschscholtz, 1829]; Eleodes oblonga Blaisdell, 1933 [= Eleodes versatilis Blaisdell, 1921]; Eleodes dentipes marinae Blaisdell, 1921 [= Eleodes dentipes Eschscholtz, 1829]; Eleodes carbonaria forma glabra Blaisdell, 1909 [= Eleodes carbonaria carbonaria (Say, 1824)]; Eleodes granosa forma fortis Blaisdell, 1909 [= Eleodes granosa LeConte, 1866]; Eleodes pilosa forma ordinata Blaisdell, 1909 [= Eleodes pilosa Horn, 1870]; Trogloderus costatus pappi Kulzer, 1960 [= Trogloderus tuberculatus Blaisdell, 1909]; Trogloderus costatus mayhewi Papp, 1961 [= Trogloderus vandykei La Rivers, 1946]; Bolitophagus cristatus Gosse, 1840 [= Bolitotherus cornutus (Fabricius, 1801)]; Eleates explanatus Casey, 1890 [= Eleates depressus (Randall, 1838)]; Blapstinus sonorae Casey, 1890 [= Blapstinus brevicollis LeConte, 1851]; Blapstinus falli Blaisdell, 1929 [= Blapstinus castaneus Casey, 1890]; Blapstinus brunneus Casey, 1890 and Blapstinus coronadensis Blaisdell, 1892 [=Blapstinus histricus Casey, 1890]; Blapstinus hesperius Casey, 1890 [=Blapstinus intermixtus Casey, 1890]; Blapstinus cinerascens Fall, 1929 [= Blapstinus lecontei Mulsant and Rey, 1859]; Blapstinus niger Casey, 1890 and Blapstinus cribricollis Casey, 1890 [= Blapstinus pimalis Casey, 1885]; Blapstinus arenarius Casey, 1890 [= Blapstinus pratensis LeConte, 1859]; Blapstinus gregalis Casey, 1890 [= Blapstinus substriatus Champion, 1885]; Blapstinus hydropicus Casey, 1890 [= Blapstinus sulcatus LeConte, 1851]; Blapstinus hospes Casey, 1890 [= Blapstinus vestitus LeConte, 1859]; Notibius reflexus Horn, 1894 [= Conibius opacus (LeConte, 1866)]; Notibius affinis Champion, 1885 [=Conibius rugipes (Champion, 1885)]; Conibius parallelus LeConte, 1851 [= Conibius seriatus LeConte, 1851]; Nocibiotes rubripes Casey, 1895 [=Nocibiotes caudatus Casey, 1895]; Nocibiotes gracilis Casey, 1895 and Nocibiotes acutus Casey, 1895 [=Nocibiotes granulatus (LeConte, 1851)]; Conibius alternatus Casey, 1890 [= Tonibius sulcatus (LeConte, 1851)]; Pedinus suturalis Say, 1824 [= Alaetrinus minimus (Palisot de Beauvois, 1817)]; Menedrio longipennis Motschulsky, 1872 [= Tenebrio obscurus Fabricius, 1792]; Hymenophorus megops Hatch, 1965 and Telesicles magnus Hatch, 1965 [= Hymenorus sinuatus Fall, 1931]; Andrimus concolor Casey, 1891 and Andrimus convergens Casey, 1891 [= Andrimus murrayi (LeConte, 1866)]; Mycetochara marshalli Campbell, 1978 [= Mycetochara perplexata Marshall, 1970]; Phaleria globosa LeConte, 1857 [= Phaleria picta Mannerheim, 1843]. The following subspecies of Trogloderus costatus LeConte, 1879 are given species rank: Trogloderus nevadus La Rivers, 1943, Trogloderus tuberculatus Blaisdell, 1909, and Trogloderus vandykei La Rivers, 1946. The following taxa, previously thought to be junior synonyms, are considered valid: Amphidora Eschscholtz, 1829; Xysta Eschscholtz, 1829; Helops confluens (Casey, 1924). Two new combinations are proposed: Stenomorpha spinimana (Champion, 1892) and Stenomorpha tenebrosa (Champion, 1892) [from the genus Parasida Casey, 1912]. The type species [placed in square brackets] of the following 12 genus-group taxa are designated for the first time: Lagriola Kirsch, 1874 [Lagriola operosa Kirsch, 1874]; Locrodes Casey, 1907 [Emmenastus piceus Casey, 1890]; Falacer Laporte, 1840 [Acanthopus cupreus Laporte, 1840 (= Helops contractus Palisot de Beauvois, 1812)]; Blapylis Horn, 1870 [Eleodes cordata Eschscholtz, 1829]; Discogenia LeConte, 1866 [Eleodes scabricula LeConte, 1858]; Metablapylis Blaisdell, 1909 [Eleodes nigrina LeConte, 1858]; Steneleodes Blaisdell, 1909 [Eleodes longicollis LeConte, 1851]; Scaptes Champion, 1886 [Scaptes squamulatus Champion, 1886 (= Asida tropica Kirsch, 1866)]; Aspidius Mulsant and Rey, 1859 [Blaps punctata Fabricius, 1792]; Cryptozoon Schaufuss, 1882 [Cryptozoon civile Schaufuss, 1882]; Halophalerus Crotch, 1874 [Phaleria rotundata LeConte, 1851]; Dignamptus LeConte, 1878 [Dignamptus stenochinus LeConte, 1878]. Two species previously known from South America [Nilio lebasi J. Thomson and Platydema erotyloides Chevrolat] are reported for the first time from North America. PMID:29416389

  3. Improved Social Interaction, Recognition and Working Memory with Cannabidiol Treatment in a Prenatal Infection (poly I:C) Rat Model

    PubMed Central

    Osborne, Ashleigh L; Solowij, Nadia; Babic, Ilijana; Huang, Xu-Feng; Weston-Green, Katrina

    2017-01-01

    Neuropsychiatric disorders such as schizophrenia are associated with cognitive impairment, including learning, memory and attention deficits. Antipsychotic drugs are limited in their efficacy to improve cognition; therefore, new therapeutic agents are required. Cannabidiol (CBD), the non-intoxicating component of cannabis, has anti-inflammatory, neuroprotective and antipsychotic-like properties; however, its ability to improve the cognitive deficits of schizophrenia remains unclear. Using a prenatal infection model, we examined the effect of chronic CBD treatment on cognition and social interaction. Time-mated pregnant Sprague-Dawley rats (n=16) were administered polyinosinic-polycytidilic acid (poly I:C) (POLY; 4 mg/kg) or saline (CONT) at gestation day 15. Male offspring (PN56) were injected twice daily with 10 mg/kg CBD (CONT+CBD, POLY+CBD; n=12 per group) or vehicle (VEH; CONT+VEH, POLY+VEH; n=12 per group) for 3 weeks. Body weight, food and water intake was measured weekly. The Novel Object Recognition and rewarded T-maze alternation tests assessed recognition and working memory, respectively, and the social interaction test assessed sociability. POLY+VEH offspring exhibited impaired recognition and working memory, and reduced social interaction compared to CONT+VEH offspring (p<0.01). CBD treatment significantly improved recognition, working memory and social interaction deficits in the poly I:C model (p<0.01 vs POLY+VEH), did not affect total body weight gain, food or water intake, and had no effect in control animals (all p>0.05). In conclusion, chronic CBD administration can attenuate the social interaction and cognitive deficits induced by prenatal poly I:C infection. These novel findings present interesting implications for potential use of CBD in treating the cognitive deficits and social withdrawal of schizophrenia. PMID:28230072

  4. Improved Social Interaction, Recognition and Working Memory with Cannabidiol Treatment in a Prenatal Infection (poly I:C) Rat Model.

    PubMed

    Osborne, Ashleigh L; Solowij, Nadia; Babic, Ilijana; Huang, Xu-Feng; Weston-Green, Katrina

    2017-06-01

    Neuropsychiatric disorders such as schizophrenia are associated with cognitive impairment, including learning, memory and attention deficits. Antipsychotic drugs are limited in their efficacy to improve cognition; therefore, new therapeutic agents are required. Cannabidiol (CBD), the non-intoxicating component of cannabis, has anti-inflammatory, neuroprotective and antipsychotic-like properties; however, its ability to improve the cognitive deficits of schizophrenia remains unclear. Using a prenatal infection model, we examined the effect of chronic CBD treatment on cognition and social interaction. Time-mated pregnant Sprague-Dawley rats (n=16) were administered polyinosinic-polycytidilic acid (poly I:C) (POLY; 4 mg/kg) or saline (CONT) at gestation day 15. Male offspring (PN56) were injected twice daily with 10 mg/kg CBD (CONT+CBD, POLY+CBD; n=12 per group) or vehicle (VEH; CONT+VEH, POLY+VEH; n=12 per group) for 3 weeks. Body weight, food and water intake was measured weekly. The Novel Object Recognition and rewarded T-maze alternation tests assessed recognition and working memory, respectively, and the social interaction test assessed sociability. POLY+VEH offspring exhibited impaired recognition and working memory, and reduced social interaction compared to CONT+VEH offspring (p<0.01). CBD treatment significantly improved recognition, working memory and social interaction deficits in the poly I:C model (p<0.01 vs POLY+VEH), did not affect total body weight gain, food or water intake, and had no effect in control animals (all p>0.05). In conclusion, chronic CBD administration can attenuate the social interaction and cognitive deficits induced by prenatal poly I:C infection. These novel findings present interesting implications for potential use of CBD in treating the cognitive deficits and social withdrawal of schizophrenia.

  5. Does repeated and heavy exercise impair blood rheology in carriers of sickle cell trait?

    PubMed

    Tripette, Julien; Hardy-Dessources, Marie-Dominique; Sara, Fagnété; Montout-Hedreville, Mona; Saint-Martin, Christian; Hue, Olivier; Connes, Philippe

    2007-11-01

    To determine if the time courses of hemorheologic parameters are different between carriers of sickle cell trait (SCT) and subjects with normal hemoglobin in response to exercise. Observational and comparative study. Testing was conducted in a laboratory of exercise physiology. Nine carriers of sickle cell trait (SCT group) and 7 subjects with normal hemoglobin (CONT group) performed an exercise protocol of the repetition of 3 successive maximal ramp exercise tests. Blood was sampled at rest (TR), at the end of each of the 3 tests (T1, T2, T3), and during the immediate (T2h) and late (T24h, T48h) recovery periods. Blood and plasma viscosity (etab and etap, respectively), hematocrit (Hct), and red blood cell (RBC) rigidity (Tk and k indexes) were determined. In both groups, etab significantly increased in response to exercise but the SCT group had significantly higher etab at T3 and T2h. etab then returned to baseline value at T2h in the CONT group and at T24h in the SCT group. Tk and k were not changed by exercise but significantly increased above baseline value in both groups at T24h and T48h. The increase in Tk and k during late recovery was higher in the SCT group than in the CONT group, indicating that SCT carriers had significantly higher RBC rigidity than the CONT group at that time. The hemorheologic changes induced by exercise in the SCT carriers could trigger microcirculatory disorders during the recovery.

  6. Continuous Exercise but Not High Intensity Interval Training Improves Fat Distribution in Overweight Adults

    PubMed Central

    Keating, Shelley E.; Machan, Elizabeth A.; O'Connor, Helen T.; Gerofi, James A.; Sainsbury, Amanda; Caterson, Ian D.; Johnson, Nathan A.

    2014-01-01

    Objective. The purpose of this study was to assess the effect of high intensity interval training (HIIT) versus continuous aerobic exercise training (CONT) or placebo (PLA) on body composition by randomized controlled design. Methods. Work capacity and body composition (dual-energy X-ray absorptiometry) were measured before and after 12 weeks of intervention in 38 previously inactive overweight adults. Results. There was a significant group × time interaction for change in work capacity (P < 0.001), which increased significantly in CONT (23.8 ± 3.0%) and HIIT (22.3 ± 3.5%) but not PLA (3.1 ± 5.0%). There was a near-significant main effect for percentage trunk fat, with trunk fat reducing in CONT by 3.1 ± 1.6% and in PLA by 1.1 ± 0.4%, but not in HIIT (increase of 0.7 ± 1.0%) (P = 0.07). There was a significant reduction in android fat percentage in CONT (2.7 ± 1.3%) and PLA (1.4 ± 0.8%) but not HIIT (increase of 0.8 ± 0.7%) (P = 0.04). Conclusion. These data suggest that HIIT may be advocated as a time-efficient strategy for eliciting comparable fitness benefits to traditional continuous exercise in inactive, overweight adults. However, in this population HIIT does not confer the same benefit to body fat levels as continuous exercise training. PMID:24669314

  7. [Lack of protection against gentamicin ototoxicity by auditory conditioning with noise].

    PubMed

    Strose, Alex; Hyppolito, Miguel Ângelo; Colombari, Gleice Cristina; Rossato, Maria; Oliveira, Jose Antônio Aparecido de

    2014-01-01

    Auditory conditioning consists of the pre-exposure to low levels of a potential harmful agent to protect against a subsequent harmful exposure. To confirm if conditioning with an agent different from that used to cause the trauma can also be effective. This was an experimental study with 17 guinea pigs, divided into three groups: an ototoxic control group (Cont) that received intramuscular administration of gentamicin 160 mg/kg/day for ten consecutive days, but no sound exposure; a sound control group (Sound) that was exposed to 85 dB broadband noise centered at 4 kHz, 30 min each day for ten consecutive days, but received no ototoxic medications; and an experimental group (Expt) that received sound exposure identical to the Sound group and after each noise presentation, received gentamicin similarly to Cont group. The animals were evaluated by distortion product otoacoustic emissions (DPOAEs), brainstem auditory evoked potentials (BAEPs), and scanning electron microscopy. The animals that were conditioned with noise did not show any protective effect compared with the ones that received only the ototoxic gentamicin administration. This lack of protection was observed functionally and morphologically. Conditioning with 85 dB broadband noises, 30 min a day for ten consecutive days does not protect against an ototoxic gentamicin administration of 160 mg/kg/day for ten consecutive days in the guinea pig. Copyright © 2014 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  8. Effects of Different Maturation Systems on Bovine Oocyte Quality, Plasma Membrane Phospholipid Composition and Resistance to Vitrification and Warming.

    PubMed

    Sprícigo, José F W; Diógenes, Mateus N; Leme, Ligiane O; Guimarães, Ana L; Muterlle, Carolle V; Silva, Bianca Damiani Marques; Solà-Oriol, David; Pivato, Ivo; Silva, Luciano Paulino; Dode, Margot A N

    2015-01-01

    The objective of this study was to evaluate the effects of different maturation systems on oocyte resistance after vitrification and on the phospholipid profile of the oocyte plasma membrane (PM). Four different maturation systems were tested: 1) in vitro maturation using immature oocytes aspirated from slaughterhouse ovaries (CONT; n = 136); 2) in vitro maturation using immature oocytes obtained by ovum pick-up (OPU) from unstimulated heifers (IMA; n = 433); 3) in vitro maturation using immature oocytes obtained by OPU from stimulated heifers (FSH; n = 444); and 4) in vivo maturation using oocytes obtained from heifers stimulated 24 hours prior by an injection of GnRH (MII; n = 658). A sample of matured oocytes from each fresh group was analyzed by matrix associated laser desorption-ionization (MALDI-TOF) to determine their PM composition. Then, half of the matured oocytes from each group were vitrified/warmed (CONT VIT, IMA VIT, FSH VIT and MII VIT), while the other half were used as fresh controls. Afterwards, the eight groups underwent IVF and IVC, and blastocyst development was assessed at D2, D7 and D8. A chi-square test was used to compare embryo development between the groups. Corresponding phospholipid ion intensity was expressed in arbitrary units, and following principal components analyses (PCA) the data were distributed on a 3D graph. Oocytes obtained from superstimulated animals showed a greater rate of developmental (P<0.05) at D7 (MII = 62.4±17.5% and FSH = 58.8±16.1%) compared to those obtained from unstimulated animals (CONT = 37.9±8.5% and IMA = 50.6±14.4%). However, the maturation system did not affect the resistance of oocytes to vitrification because the blastocyst rate at D7 was similar (P>0.05) for all groups (CONT VIT = 2.8±3.5%, IMA VIT = 2.9±4.0%, FSH VIT = 4.3±7.2% and MII VIT = 3.6±7.2%). MALDI-TOF revealed that oocytes from all maturation groups had similar phospholipid contents, except for 760.6 ([PC (34:1) + H]+), which was more highly expressed in MII compared to FSH (P<0.05). The results suggest that although maturation systems improve embryonic development, they do not change the PM composition nor the resistance of bovine oocytes to vitrification.

  9. Effects of Different Maturation Systems on Bovine Oocyte Quality, Plasma Membrane Phospholipid Composition and Resistance to Vitrification and Warming

    PubMed Central

    Sprícigo, José F. W.; Diógenes, Mateus N.; Leme, Ligiane O.; Guimarães, Ana L.; Muterlle, Carolle V.; Silva, Bianca Damiani Marques; Solà-Oriol, David; Pivato, Ivo; Silva, Luciano Paulino; Dode, Margot A. N.

    2015-01-01

    The objective of this study was to evaluate the effects of different maturation systems on oocyte resistance after vitrification and on the phospholipid profile of the oocyte plasma membrane (PM). Four different maturation systems were tested: 1) in vitro maturation using immature oocytes aspirated from slaughterhouse ovaries (CONT; n = 136); 2) in vitro maturation using immature oocytes obtained by ovum pick-up (OPU) from unstimulated heifers (IMA; n = 433); 3) in vitro maturation using immature oocytes obtained by OPU from stimulated heifers (FSH; n = 444); and 4) in vivo maturation using oocytes obtained from heifers stimulated 24 hours prior by an injection of GnRH (MII; n = 658). A sample of matured oocytes from each fresh group was analyzed by matrix associated laser desorption-ionization (MALDI-TOF) to determine their PM composition. Then, half of the matured oocytes from each group were vitrified/warmed (CONT VIT, IMA VIT, FSH VIT and MII VIT), while the other half were used as fresh controls. Afterwards, the eight groups underwent IVF and IVC, and blastocyst development was assessed at D2, D7 and D8. A chi-square test was used to compare embryo development between the groups. Corresponding phospholipid ion intensity was expressed in arbitrary units, and following principal components analyses (PCA) the data were distributed on a 3D graph. Oocytes obtained from superstimulated animals showed a greater rate of developmental (P<0.05) at D7 (MII = 62.4±17.5% and FSH = 58.8±16.1%) compared to those obtained from unstimulated animals (CONT = 37.9±8.5% and IMA = 50.6±14.4%). However, the maturation system did not affect the resistance of oocytes to vitrification because the blastocyst rate at D7 was similar (P>0.05) for all groups (CONT VIT = 2.8±3.5%, IMA VIT = 2.9±4.0%, FSH VIT = 4.3±7.2% and MII VIT = 3.6±7.2%). MALDI-TOF revealed that oocytes from all maturation groups had similar phospholipid contents, except for 760.6 ([PC (34:1) + H]+), which was more highly expressed in MII compared to FSH (P<0.05). The results suggest that although maturation systems improve embryonic development, they do not change the PM composition nor the resistance of bovine oocytes to vitrification. PMID:26107169

  10. Effect of ensiled mulberry leaves and sun-dried mulberry fruit pomace on finishing steer growth performance, blood biochemical parameters, and carcass characteristics.

    PubMed

    Zhou, Zhenming; Zhou, Bo; Ren, Liping; Meng, Qingxiang

    2014-01-01

    Fifty-one Simmental crossbred steers (357.0 ± 16.5 kg) were used to compare a standard total mix ration (TMR) with variants on animal performance, ruminal fermentation, blood biochemical parameters, and carcass characteristics. Corn grain and cotton seed meal were partially replaced by ensiled mulberry leaves (EML) or sun-dried mulberry fruit pomace (SMFP). Experimental diets had similar amounts of crude protein (CP), acid detergent fiber (ADF), and metabolizable energy (ME). Animals were divided into three groups: control group (CONT), 8% EML group, and 6.3% SMFP group. Performance, including average daily weight gain (ADG), and dry matter intake (DMI), was measured. Blood and rumen samples were collected at the end of the experiment (16 weeks). There were no differences in final body weight (P = 0.743), ADG (P = 0.425), DMI (P = 0.642), or ADG/DMI (P = 0.236) between the groups. There were no differences (P = 0.2024) in rumen pH values; ammonia N was lower (P = 0.0076) in SMFP than in the EML and CONT groups. There were differences in the concentrations of total and individual volatile fatty acids, while no differences were determined in blood biochemical parameters (i.e., plasma glucose, urea concentrations, triglycerides, total protein, insulin, IgG, alanine transaminase, and aspartate aminotransferase, P ≥ 0.098). No differences were observed in carcass characteristics (P ≥ 0.513), tenderness (P = 0.844), adipose and lean color values (P ≥ 0.149), and chemical composition (P ≥ 0.400); however, intramuscular fat was lower in the EML and SMFP groups compared to the CONT animals (P = 0.034). In conclusion, diets supplemented with these two mulberry products in an isocaloric and isonitrogenous manner have similar effects to corn grain and cotton seed meals on steer performance, blood biochemical parameters and carcass characteristics, with the exception of ruminal VFA concentrations and lower intramuscular fat content.

  11. Impact of video game genre on surgical skills development: a feasibility study.

    PubMed

    de Araujo, Thiago Bozzi; Silveira, Filipe Rodrigues; Souza, Dante Lucas Santos; Strey, Yuri Thomé Machado; Flores, Cecilia Dias; Webster, Ronaldo Scholze

    2016-03-01

    The playing of video games (VGs) was previously shown to improve surgical skills. This is the first randomized, controlled study to assess the impact of VG genre on the development of basic surgical skills. Twenty first-year, surgically inexperienced medical students attended a practical course on surgical knots, suturing, and skin-flap technique. Later, they were randomized into four groups: control and/or nongaming (ContG), first-person-shooter game (ShotG), racing game (RaceG), and surgery game (SurgG). All participants had 3 wk of Nintendo Wii training. Surgical and VG performances were assessed by two independent, blinded surgeons who evaluated basal performance (time 0) and performance after 1 wk (time 1) and 3 wk (time 2) of training. The training time of RaceG was longer than that of ShotG and SurgG (P = 0.045). Compared to SurgG and RaceG, VG scores for ShotG improved less between times 0 and 1 (P = 0.010) but more between times 1 and 2 (P = 0.004). Improvement in mean surgical performance scores versus time differed in each VG group (P = 0.011). At time 2, surgical performance scores were significantly higher in ShotG (P = 0.002) and SurgG (P = 0.022) than in ContG. The surgical performance scores of RaceG were not significantly different from the score achieved by ContG (P = 0.279). Different VG genres may differentially impact the development of surgical skills by medical students. More complex games seem to improve performance even if played less. Although further studies are needed, surgery-related VGs with sufficient complexity and playability could be a feasible adjuvant to improving surgical skills. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Effect of dietary sodium on fluid/electrolyte regulation during bed rest

    NASA Technical Reports Server (NTRS)

    Williams, W. Jon; Schneider, Suzanne M.; Gretebeck, Randall J.; Lane, Helen W.; Stuart, Charles A.; Whitson, Peggy A.

    2003-01-01

    BACKGROUND: A negative fluid balance during bed rest (BR) is accompanied by decreased plasma volume (PV) which contributes to cardiovascular deconditioning. HYPOTHESIS: We hypothesized that increasing dietary sodium while controlling fluid intake would increase plasma osmolality (POSM), stimulate fluid conserving hormones, and reduce fluid/electrolyte (F/E) losses during BR; conversely, decreasing dietary sodium would decrease POSM, suppress fluid conserving hormones, and increase F/E losses. METHODS: We controlled fluid intake (30 ml x kg(-1) x d(-1)) in 17 men who consumed either a 4.0 +/- 0.06 g x d(-1) (174 mmol x d(-1)) (CONT; n = 6), 1.0 +/- 0.02 g x d(-1) (43 mmol x d(-1)) (LS; n = 6), or 10.0 +/- 0.04 g x d(-1) (430 mmol x d(-1)) (HS; n = 5) sodium diet before, during, and after 21 d of 6 degrees head-down BR. PV, total body water, urine volume and osmolality, POSM, and F/E controlling hormone concentrations were measured. RESULTS: In HS subjects, plasma renin activity (-92%), plasma/urinary aldosterone (-59%; -64%), and PV (-15.0%; 6.0 ml x kg(-1); p < 0.05) decreased while plasma atrial natriuretic peptide (+34%) and urine antidiuretic hormone (+24%) increased during BR (p < 0.05) compared with CONT. In LS, plasma renin activity (+166%), plasma aldosterone (+167%), plasma antidiuretic hormone (+19%), and urinary aldosterone (+335%) increased with no change in PV compared with CONT (p < 0.05). Total body water did not change in any of the subjects. CONCLUSIONS: Contrary to our hypothesis, increasing dietary sodium while controlling fluid intake during BR resulted in a greater loss of PV compared with the CONT subjects. Reducing dietary sodium while controlling fluid intake did not alter the PV response during BR compared with CONT subjects.

  13. Acute effects of high-intensity interval training and moderate-intensity continuous training sessions on cardiorespiratory parameters in healthy young men.

    PubMed

    Schaun, Gustavo Zaccaria; Alberton, Cristine Lima; Ribeiro, Diego Oliveira; Pinto, Stephanie Santana

    2017-07-01

    The aim of the present study was to compare the energy expenditure (EE) during and after two treadmill protocols, high-intensity interval training (HIIT) and moderate continuous training (CONT), in young adult men. The sample was comprised by 26 physically active men aged between 18 and 35 years engaged in aerobic training programs. They were divided into two groups: HIIT (n = 14) which performed eight 20 s bouts at 130% of the velocity associated with the maximal oxygen consumption on a treadmill with 10 s of passive rest, or CONT (n = 12) which performed 30 min running on a treadmill at a submaximal velocity equivalent to 90-95% of the heart rate associated with the anaerobic threshold. Data related to oxygen consumption ([Formula: see text]) and EE were measured during the protocols and the excess post-exercise oxygen consumption (EPOC) was calculated for both sessions. No difference was found between groups for mean [Formula: see text] (HIIT: 2.84 ± 0.46 L min -1 ; CONT: 2.72 ± 0.43 L min -1 ) and EE per minute (HIIT: 14.36 ± 2.34 kcal min -1 ; CONT: 13.21 ± 2.08 kcal min -1 ) during protocols. Regarding total EE during session, CONT resulted in higher values compared to HIIT (390.45 ± 65.15; 55.20 ± 9.33 kcal, respectively). However, post-exercise EE and EPOC values were higher after HIIT (69.31 ± 10.88; 26.27 ± 2.28 kcal, respectively) compared to CONT (55.99 ± 10.20; 13.43 ± 10.45 kcal, respectively). These data suggest that supramaximal HIIT has a higher impact on EE and EPOC in the early phase of recovery when compared to CONT.

  14. Reduction in heat-induced gastrointestinal hyperpermeability in rats by bovine colostrum and goat milk powders.

    PubMed

    Prosser, C; Stelwagen, K; Cummins, R; Guerin, P; Gill, N; Milne, C

    2004-02-01

    Male Sprague-Dawley rats were assigned to one of three dietary groups [standard diet (Cont; n = 8), standard diet plus bovine colostrum powder (BColost 1.7 g/kg; n = 8), or goat milk powder (GMilk 1.7 g/kg; n = 8)] to determine the ability of these supplements to reduce gastrointestinal hyperpermeability induced by heat. Raising core body temperature of rats to 41.5 degrees C increased transfer of (51)Cr-EDTA from gut into blood 34-fold relative to the ambient temperature value (P < 0.05) in the Cont group of rats, indicative of increased gastrointestinal permeability. Significantly less (P < 0.01) (51)Cr-EDTA was transferred into the blood of rats in either the BColost (27% of Cont) or GMilk group (10% of Cont) after heating, showing that prior supplementation with either bovine colostrum or goat milk powder significantly reduced the impact of heat stress on gastrointestinal permeability. The changes in the BColost group were not significantly different than those of the GMilk group. The potential mechanism of the protective effect of bovine colostrum and goat milk powders may involve modulation of tight junction permeability, because both powders were able to maintain transepithelial resistance in Madin Darby canine kidney cells challenged with EGTA compared with cells maintained in media only. The results show that bovine colostrum powder can partially alleviate the effects of hyperthermia on gastrointestinal permeability in the intact animal. Moreover, goat milk powder was equally as effective as bovine colostrum powder, and both may be of benefit in other situations where gastrointestinal barrier function is compromised.

  15. Exogenous melatonin administration modifies cutaneous vasoconstrictor response to whole body skin cooling in humans.

    PubMed

    Aoki, Ken; Zhao, Kun; Yamazaki, Fumio; Sone, Ryoko; Alvarez, Guy E; Kosiba, Wojciech A; Johnson, John M

    2008-03-01

    Humans and other diurnal species experience a fall in internal temperature (T(int)) at night, accompanied by increased melatonin and altered thermoregulatory control of skin blood flow (SkBF). Also, exogenous melatonin induces a fall in T(int), an increase in distal skin temperatures and altered control of the cutaneous active vasodilator system, suggesting an effect of melatonin on the control of SkBF. To test whether exogenous melatonin also affects the more tonically active vasoconstrictor system in glabrous and nonglabrous skin during cooling, healthy males (n = 9) underwent afternoon sessions of whole body skin temperature (T(sk)) cooling (water-perfused suits) after oral melatonin (Mel; 3 mg) or placebo (Cont). Cutaneous vascular conductance (CVC) was calculated from SkBF (laser Doppler flowmetry) and non-invasive blood pressure. Baseline T(int) was lower in Mel than in Cont (P < 0.01). During progressive reduction of T(sk) from 35 degrees C to 32 degrees C, forearm CVC was first significantly reduced at T(sk) of 34.33 +/- 0.01 degrees C (P < 0.05) in Cont. In contrast, CVC in Mel was not significantly reduced until T(sk) reached 33.33 +/- 0.01 degrees C (P < 0.01). The decrease in forearm CVC in Mel was significantly less than in Cont at T(sk) of 32.66 +/- 0.01 degrees C and lower (P < 0.05). In Mel, palmar CVC was significantly higher than in Cont above T(sk) of 33.33 +/- 0.01 degrees C, but not below. Thus exogenous melatonin blunts reflex vasoconstriction in nonglabrous skin and shifts vasoconstrictor system control to lower T(int). It provokes vasodilation in glabrous skin but does not suppress the sensitivity to falling T(sk). These findings suggest that by affecting the vasoconstrictor system, melatonin has a causal role in the nocturnal changes in body temperature and its control.

  16. Effect of Ensiled Mulberry Leaves and Sun-Dried Mulberry Fruit Pomace on Finishing Steer Growth Performance, Blood Biochemical Parameters, and Carcass Characteristics

    PubMed Central

    Zhou, Zhenming; Zhou, Bo; Ren, Liping; Meng, Qingxiang

    2014-01-01

    Fifty-one Simmental crossbred steers (357.0±16.5 kg) were used to compare a standard total mix ration (TMR) with variants on animal performance, ruminal fermentation, blood biochemical parameters, and carcass characteristics. Corn grain and cotton seed meal were partially replaced by ensiled mulberry leaves (EML) or sun-dried mulberry fruit pomace (SMFP). Experimental diets had similar amounts of crude protein (CP), acid detergent fiber (ADF), and metabolizable energy (ME). Animals were divided into three groups: control group (CONT), 8% EML group, and 6.3% SMFP group. Performance, including average daily weight gain (ADG), and dry matter intake (DMI), was measured. Blood and rumen samples were collected at the end of the experiment (16 weeks). There were no differences in final body weight (P = 0.743), ADG (P = 0.425), DMI (P = 0.642), or ADG/DMI (P = 0.236) between the groups. There were no differences (P = 0.2024) in rumen pH values; ammonia N was lower (P = 0.0076) in SMFP than in the EML and CONT groups. There were differences in the concentrations of total and individual volatile fatty acids, while no differences were determined in blood biochemical parameters (i.e., plasma glucose, urea concentrations, triglycerides, total protein, insulin, IgG, alanine transaminase, and aspartate aminotransferase, P ≥ 0.098). No differences were observed in carcass characteristics (P ≥ 0.513), tenderness (P = 0.844), adipose and lean color values (P ≥ 0.149), and chemical composition (P ≥ 0.400); however, intramuscular fat was lower in the EML and SMFP groups compared to the CONT animals (P = 0.034). In conclusion, diets supplemented with these two mulberry products in an isocaloric and isonitrogenous manner have similar effects to corn grain and cotton seed meals on steer performance, blood biochemical parameters and carcass characteristics, with the exception of ruminal VFA concentrations and lower intramuscular fat content. PMID:24427304

  17. Programming and supervision of resistance training leads to positive effects on strength and body composition: results from two randomised trials of community fitness programmes.

    PubMed

    Mann, Steven; Jimenez, Alfonso; Steele, James; Domone, Sarah; Wade, Matthew; Beedie, Chris

    2018-03-27

    Many sedentary adults have high body fat along with low fitness, strength, and lean body mass (LBM) which are associated with poor health independently of body mass. Physical activity can aid in prevention, management, and treatment of numerous chronic conditions. The potential efficacy of resistance training (RT) in modifying risk factors for cardiovascular and metabolic disease is clear. However, RT is under researched in public health. We report community-based studies of RT in sedentary (Study 1), and overweight and pre-diabetic (Study 2) populations. Study 1 - A semi randomised trial design (48-weeks): Participants choosing either a fitness centre approach, and randomised to structured-exercise (STRUC, n = 107), or free/unstructured gym use (FREE, n = 110), or not, and randomised to physical-activity-counselling (PAC, n = 71) or a measurement only comparator (CONT, n = 76). Study 2 - A randomised wait list controlled trial (12-weeks): Patients were randomly assigned to; traditional-supervised-exercise (STRUC, n = 30), physical-activity-counselling (PAC, n = 23), either combined (COMB, n = 39), or a wait-list comparator (CONT, n = 54). Outcomes for both were BF mass (kg), LBM (kg), BF percentage (%), and strength. Study 1: One-way ANCOVA revealed significant between group effects for BF% and LBM, but not for BF mass or strength. Post hoc paired comparisons revealed significantly greater change in LBM for the STRUC group compared with the CONT group. Within group changes using 95%CIs revealed significant changes only in the STRUC group for both BF% (- 4.1 to - 0.9%) and LBM (0.1 to 4.5 kg), and in FREE (8.2 to 28.5 kg) and STRUC (5.9 to 26.0 kg) for strength. Study 2: One-way ANCOVA did not reveal significant between group effects for strength, BF%, BF mass, or LBM. For strength, 95%CIs revealed significant within group changes for the STRUC (2.4 to 14.1 kg) and COMB (3.7 to 15.0 kg) groups. Strength increased in both studies across all RT treatments compared to controls, yet significant improvements in both strength and body-composition occurred only in programmed and/or supervised RT. As general increases in physical activity have limited impact upon body-composition, public health practitioners should structure interventions to include progressive RT. Study 1: ISRCTN13024854 , retrospectively registered 20/02/2018. Study 2: ISRCTN13509468 , retrospectively registered 20/02/2018).

  18. Predicting depressed patients with suicidal ideation from ECG recordings.

    PubMed

    Khandoker, A H; Luthra, V; Abouallaban, Y; Saha, S; Ahmed, K I; Mostafa, R; Chowdhury, N; Jelinek, H F

    2017-05-01

    Globally suicidal behavior is the third most common cause of death among patients with major depressive disorder (MDD). This study presents multi-lag tone-entropy (T-E) analysis of heart rate variability (HRV) as a screening tool for identifying MDD patients with suicidal ideation. Sixty-one ECG recordings (10 min) were acquired and analyzed from control subjects (29 CONT), 16 MDD subjects with (MDDSI+) and 16 without suicidal ideation (MDDSI-). After ECG preprocessing, tone and entropy values were calculated for multiple lags (m: 1-10). The MDDSI+ group was found to have a higher mean tone value compared to that of the MDDSI- group for lags 1-8, whereas the mean entropy value was lower in MDDSI+ than that in CONT group at all lags (1-10). Leave-one-out cross-validation tests, using a classification and regression tree (CART), obtained 94.83 % accuracy in predicting MDDSI+ subjects by using a combination of tone and entropy values at all lags and including demographic factors (age, BMI and waist circumference) compared to results with time and frequency domain HRV analysis. The results of this pilot study demonstrate the usefulness of multi-lag T-E analysis in identifying MDD patients with suicidal ideation and highlight the change in autonomic nervous system modulation of the heart rate associated with depression and suicidal ideation.

  19. Aerobic interval training reduces vascular resistances during submaximal exercise in obese metabolic syndrome individuals.

    PubMed

    Mora-Rodriguez, Ricardo; Fernandez-Elias, V E; Morales-Palomo, F; Pallares, J G; Ramirez-Jimenez, M; Ortega, J F

    2017-10-01

    The aim of this study was to determine the effects of high-intensity aerobic interval training (AIT) on exercise hemodynamics in metabolic syndrome (MetS) volunteers. Thirty-eight, MetS participants were randomly assigned to a training (TRAIN) or to a non-training control (CONT) group. TRAIN consisted of stationary interval cycling alternating bouts at 70-90% of maximal heart rate during 45 min day -1 for 6 months. CONT maintained baseline physical activity and no changes in cardiovascular function or MetS factors were detected. In contrast, TRAIN increased cardiorespiratory fitness (14% in VO 2PEAK ; 95% CI 9-18%) and improved metabolic syndrome (-42% in Z score; 95% CI 83-1%). After TRAIN, the workload that elicited a VO 2 of 1500 ml min -1 increased 15% (95% CI 5-25%; P < 0.001). After TRAIN when subjects pedaled at an identical submaximal rate of oxygen consumption, cardiac output increased by 8% (95% CI 4-11%; P < 0.01) and stroke volume by 10% (95% CI, 6-14%; P < 0.005) being above the CONT group values at that time point. TRAIN reduced submaximal exercise heart rate (109 ± 15-106 ± 13 beats min -1 ; P < 0.05), diastolic blood pressure (83 ± 8-75 ± 8 mmHg; P < 0.001) and systemic vascular resistances (P < 0.01) below CONT values. Double product was reduced only after TRAIN (18.2 ± 3.2-17.4 ± 2.4 bt min -1  mmHg 10 -3 ; P < 0.05). The data suggest that intense aerobic interval training improves hemodynamics during submaximal exercise in MetS patients. Specifically, it reduces diastolic blood pressure, systemic vascular resistances, and the double product. The reduction in double product, suggests decreased myocardial oxygen demands which could prevent the occurrence of adverse cardiovascular events during exercise in this population. CLINICALTRIALS. NCT03019796.

  20. Distribution characteristics of the fish assemblages to varying environmental conditions in artificial reefs of the Jeju Island, Korea.

    PubMed

    Noh, Junsung; Ryu, Jongseong; Lee, Dowon; Khim, Jong Seong

    2017-05-15

    Artificial reefs (ARs) have long been practiced to manage and enhance fisheries resources worldwide. Here, we aimed to identify relevant indicator species for the specific environmental conditions of ARs by comparing fish diversity against control sites (Conts). We used a combination of non-metric multidimensional scaling and indicator value analysis to identify the indicator species of the specific AR environments. More individuals and species of fish were present in ARs compared to Conts. Water temperature over the seasons was the most important environmental factor associated with the trophic group composition of fish. In particular, macrocarnivores and benthic invertivores/cleaners closely reflected habitat conditions in a consistent manner. Some dominant fish species were detected at all sites, while the indicator species were more predominant under certain environmental conditions. Altogether, ARs should be monitored at regular intervals to optimize management of their health by detecting the community representativeness via indicator species. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Novel dynamic peak and distribution plantar pressure measures on diabetic patients during walking.

    PubMed

    Al-Angari, Haitham M; Khandoker, Ahsan H; Lee, Sungmun; Almahmeed, Wael; Al Safar, Habiba S; Jelinek, Herbert F; Khalaf, Kinda

    2017-01-01

    Diabetic peripheral neuropathy (DPN) is a common complication leading to foot ulceration and amputation. Several kinematic, kinetic and plantar pressure measures have been proposed for DPN detection, however findings have been inconsistent. In this work, we present new shape features that capture variations in the plantar pressure using shape and entropy measures to the study of patients with retinopathy, DPN and nephropathy, and a control diabetic group with no complications. The change in the peak plantar pressure (PPP) position with each step for both feet was represented as a convex polygon, asymmetry index, area of the convex polygon, 2nd wavelet moment (WM2) and sample entropy (SamEn). WM2 and the SamEn were more sensitive in capturing variations due to presence of complications than the area and asymmetry measures. WM2 of the left heel (median: 1st IQ, 3rd IQ): 8.27 (4.6,14.8) and left forefoot: 9.2 (2.4,16) were significantly lower for the DPN group compared to the control (CONT) group (heel 11.9 (5.0,16.4); forefoot: 10.3 (4.4,21.3), p < 0.05). SamEn for the DPN group was significantly lower in the right foot compared to the left foot (1.3 (1.26, 1.37) and 1.33 (1.26,1.4), p < 0.01) compared to CONT (right foot: 1.37 (1.24,1.45) and left foot: 1.34 (1.25,1.42), P < 0.05). These new shape and regularity features have shown promising results in detecting diabetic peripheral neuropathy and warrant further investigation. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Uterine insemination with a standard AI dose in a sow pool system.

    PubMed

    Peltoniemi, O A T; Alm, K; Andersson, M

    2009-06-01

    The effect of uterine AI with a standard dose of spermatozoa on fertility of the sow was studied in a field trial. The trial involved a sow pool system with 440 sows using AI as the primary method of breeding. Sows were twice a day checked for oestrus symptoms by back pressure test in front of a boar on days 3-6 after weaning. When in standing heat, sows were randomly allocated into either a uterine insemination group (UTER, n = 157) or standard AI group (CONT, n = 169) and bred accordingly using 3 billion spermatozoa in 80 ml of extender. In both treatment groups, insemination was repeated once if the sow was still receptive 24 h later. Using pregnancy (farrowed or not) and live-born litter size as the outcome variables, a logistic and linear regression approach, respectively, was taken to study the effect of the following factors: treatment (UTER vs CONT), AI operator, breed, satellite herd preceding weaning, parity, weaning-to-oestrus interval and length of lactation. Overall, live-born litter size was 11.3 +/- 2.9, repeat breeding rate 4.2% and farrowing rate 91.2%. In the UTER group, 93.6% of inseminated sows farrowed, whereas farrowing rate for the CONT group was 88.8% (p = 0.13). Intrauterine insemination with a standard AI dose did not result in a significant improvement in the live-born litter size (11.5 +/- 2.8 for the UTER and 11.1 +/- 3.0 for the CONT sows, respectively, p = 0.13). However, the preceding satellite herd had a highly significant effect on the live-born litter size (12.4 +/- 2.6; 11.1 +/- 2.9; 10.8 +/- 2.9 and 10.9 +/- 2.9 for the four satellite herds, p < 0.01). We conclude that uterine insemination did not have a significant effect on live-born litter size and farrowing rate and we also conclude that satellite herd appears to have a major effect on fertility in a sow pool system.

  3. Circulating angiotensin-converting enzyme 2 activity in patients with chronic kidney disease without previous history of cardiovascular disease.

    PubMed

    Anguiano, Lidia; Riera, Marta; Pascual, Julio; Valdivielso, José Manuel; Barrios, Clara; Betriu, Angels; Mojal, Sergi; Fernández, Elvira; Soler, María José

    2015-07-01

    Patients with cardiovascular (CV) disease have an increased circulating angiotensin-converting enzyme 2 (ACE2) activity, but there is little information about changes in ACE2 in chronic kidney disease (CKD) patients without history of CV disease. We examined circulating ACE2 activity in CKD patients at stages 3-5 (CKD3-5) and in dialysis (CKD5D) without any history of CV disease. Circulating ACE2 activity was measured in human ethylenediamine-tetraacetic acid (EDTA)-plasma samples from the NEFRONA study (n = 2572): control group (CONT) (n = 568), CKD3-5 (n = 1458) and CKD5D (n = 546). Different clinical and analytical variables such as gender; age; history of diabetes mellitus (DM), dyslipidemia and hypertension; glycaemic, renal, lipid and anaemia profiles; vitamin D analogues treatment and antihypertensive treatments (angiotensin-converting enzyme inhibitor and angiotensin receptor blockade) were analysed. Circulating ACE2 and ACE activities were measured using modified fluorimetric assay for EDTA-plasma samples, where zinc chloride was added to recover enzymatic activity. In CKD3-5 and CKD5D, significant decrease in circulating ACE2 activity was observed when compared with CONT, but no differences were found between CKD3-5 and CKD5 when performing paired case-control studies. By multivariate linear regression analysis, male gender and advanced age were identified as independent predictors of ACE2 activity in all groups. Diabetes was identified as independent predictor of ACE2 activity in CKD3-5. Significant increase in the activity of circulating ACE was found in CKD3-5 and CKD5D when compared with CONT and in CKD5D when compared with CKD3-5. By multiple regression analysis, female gender and younger age were identified as independent predictors of ACE activity in CONT and CKD3-5. Diabetes was also identified as an independent predictor of ACE activity in CKD3-5 patients. Circulating ACE2 and ACE activities can be measured in human EDTA-plasma samples with zinc added to recover enzymatic activity. In a CKD population without previous history of CV disease, ACE2 activity from human EDTA-plasma samples directly correlated with the classical CV risk factors namely older age, diabetes and male gender. Our data suggest that circulating ACE2 is altered in CKD patients at risk for CV event. © The Author 2015. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

  4. Mental health among young adult survivors of childhood cancer and their siblings including posttraumatic growth.

    PubMed

    Kamibeppu, Kiyoko; Sato, Iori; Honda, Misato; Ozono, Shuichi; Sakamoto, Naoko; Iwai, Tsuyako; Okamura, Jun; Asami, Keiko; Maeda, Naoko; Inada, Hiroko; Kakee, Naoko; Horibe, Keizo; Ishida, Yasushi

    2010-12-01

    Few studies have addressed the mental health status of young adult childhood cancer survivors (CCSs) and their siblings (SIBs). This paper focuses on depression, anxiety, posttraumatic stress symptoms (PTSS), and posttraumatic growth (PTG) among Japanese CCSs and their SIBs. Adolescent and young adult CCSs (n=185), in remission for more than 1 year, their SIBs (n=72), and general controls (CONTs) (n=1,000) completed anonymous self-report questionnaires for depression, anxiety, PTSS, and PTG. The physicians in charge also completed an anonymous disease/treatment data sheet. CCSs were approximately 8 years old at diagnosis and approximately 23 years old at the time of the survey. Their diagnoses included leukemia (57%), lymphoma (12%), and solid tumors (30%). Thirty-eight percent underwent surgery and 25% received stem cell transplantation. No significant differences were found between CCSs and CONTs in terms of depression and anxiety. CCSs had significantly more PTSS and had remarkably greater PTG compared to CONTs. Although no significant differences were found between SIBs and CONTs regarding depression, anxiety, or PTSS, female SIBs exhibited greater PTG compared to female CONTs. To empower CCSs, they should be evaluated periodically regarding PTSS and PTG and should be provided appropriate care and feedback. The fact that the mental health status of young adult SIBs was similar to CONTs at 15 years after their siblings' diagnoses may help reassure parents who worry about mental health among the siblings of an affected child during and after his/her treatment.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ledee, Dolena R.; Smith, Lincoln; Kajimoto, Masaki

    Pressure overload cardiac hypertrophy alters substrate metabolism. Prior work showed that myocardial inactivation of c-Myc (Myc) attenuated hypertrophy and decreased expression of glycolytic genes after aortic constriction. Accordingly, we hypothesize that Myc regulates substrate preferences for the citric acid cycle during pressure overload hypertrophy from transverse aortic constriction (TAC) and that these metabolic changes impact cardiac function and growth. To test this hypothesis, we subjected FVB mice with cardiac specific, inducible Myc inactivation (MycKO-TAC) and non-transgenic littermates (Cont-TAC) to transverse aortic constriction (n=7/group). A separate group underwent sham surgery (Sham, n=5). After two weeks, function was measured in isolated workingmore » hearts along with substrate fractional contributions to the citric acid cycle by using perfusate with 13C labeled mixed fatty acids, lactate, ketones and unlabeled glucose and insulin. Western blots were used to evaluate metabolic enzymes. Cardiac function was similar between groups after TAC although +dP/dT and -dP/dT trended towards improvement in MycKO-TAC versus Cont-TAC. Compared to Sham, Cont-TAC had increased free fatty acid fractional contribution with a concurrent decrease in unlabeled (presumably glucose) contribution. Myc inactivation (MycKO-TAC) inhibited these metabolic changes. Hypertrophy in general increased protein levels of PKM2; however this change was not linked to Myc status. Protein post-translation modification by O-GlcNAc was significantly greater in Cont-TAC versus both Sham and MycKO-TAC. In conclusion, Myc regulates substrate utilization during early pressure overload hypertrophy. Our results show that the metabolic switch during hypertrophy is not necessary to maintain cardiac function, but it may be important mechanism to promote cardiomyocyte growth. Myc also regulates protein O-GlcNAcylation during hypertrophy.« less

  6. c-Myc alters substrate utilization and O-GlcNAc protein posttranslational modifications without altering cardiac function during early aortic constriction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ledee, Dolena; Smith, Lincoln; Bruce, Margaret

    Pressure overload cardiac hypertrophy alters substrate metabolism. Prior work showed that myocardial inactivation of c-Myc (Myc) attenuated hypertrophy and decreased expression of metabolic genes after aortic constriction. Accordingly, we hypothesize that Myc regulates substrate preferences for the citric acid cycle during pressure overload hypertrophy from transverse aortic constriction (TAC) and that these metabolic changes impact cardiac function and growth. To test this hypothesis, we subjected mice with cardiac specific, inducible Myc inactivation (MycKO-TAC) and non-transgenic littermates (Cont-TAC) to transverse aortic constriction (TAC; n=7/group). A separate group underwent sham surgery (Sham, n=5). After two weeks, function was measured in isolated workingmore » hearts along with substrate fractional contributions to the citric acid cycle by using perfusate with 13C labeled mixed fatty acids, lactate, ketone bodies and unlabeled glucose and insulin. Cardiac function was similar between groups after TAC although +dP/dT and -dP/dT trended towards improvement in MycKO-TAC versus Cont-TAC. Compared to Sham, Cont-TAC had increased free fatty acid fractional contribution with a concurrent decrease in unlabeled (predominately glucose) contribution. The changes in free fatty acid and unlabeled fractional contributions were abrogated by Myc inactivation during TAC (MycKO-TAC). Additionally, protein posttranslational modification by O-GlcNAc was significantly greater in Cont-TAC versus both Sham and MycKO-TAC. Lastly, Myc alters substrate preferences for the citric acid cycle during early pressure overload hypertrophy without negatively affecting cardiac function. Myc also affects protein posttranslational modifications by O-GlcNAc during hypertrophy.« less

  7. c-Myc alters substrate utilization and O-GlcNAc protein posttranslational modifications without altering cardiac function during early aortic constriction

    DOE PAGES

    Ledee, Dolena; Smith, Lincoln; Bruce, Margaret; ...

    2015-08-12

    Pressure overload cardiac hypertrophy alters substrate metabolism. Prior work showed that myocardial inactivation of c-Myc (Myc) attenuated hypertrophy and decreased expression of metabolic genes after aortic constriction. Accordingly, we hypothesize that Myc regulates substrate preferences for the citric acid cycle during pressure overload hypertrophy from transverse aortic constriction (TAC) and that these metabolic changes impact cardiac function and growth. To test this hypothesis, we subjected mice with cardiac specific, inducible Myc inactivation (MycKO-TAC) and non-transgenic littermates (Cont-TAC) to transverse aortic constriction (TAC; n=7/group). A separate group underwent sham surgery (Sham, n=5). After two weeks, function was measured in isolated workingmore » hearts along with substrate fractional contributions to the citric acid cycle by using perfusate with 13C labeled mixed fatty acids, lactate, ketone bodies and unlabeled glucose and insulin. Cardiac function was similar between groups after TAC although +dP/dT and -dP/dT trended towards improvement in MycKO-TAC versus Cont-TAC. Compared to Sham, Cont-TAC had increased free fatty acid fractional contribution with a concurrent decrease in unlabeled (predominately glucose) contribution. The changes in free fatty acid and unlabeled fractional contributions were abrogated by Myc inactivation during TAC (MycKO-TAC). Additionally, protein posttranslational modification by O-GlcNAc was significantly greater in Cont-TAC versus both Sham and MycKO-TAC. Lastly, Myc alters substrate preferences for the citric acid cycle during early pressure overload hypertrophy without negatively affecting cardiac function. Myc also affects protein posttranslational modifications by O-GlcNAc during hypertrophy.« less

  8. UV irradiation improves the bond strength of resin cement to fiber posts.

    PubMed

    Zhong, Bo; Zhang, Yong; Zhou, Jianfeng; Chen, Li; Li, Deli; Tan, Jianguo

    2011-01-01

    The purpose is to evaluate the effect of UV irradiation on the bond strength between epoxy-based glass fiber posts and resin cement. Twelve epoxy-based glass fiber posts were randomly divided into three groups. Group 1 (Cont.): No surface treatment. Group 2 (Low-UV): UV irradiation was conducted from a distance of 10 cm for 10 min. Group 3 (High-UV): UV irradiation was conducted from a distance of 1 cm for 3 min. A resin cement (CLEARFIL SA LUTING) was used for the post cementation to form resin slabs which contained fiber posts in the center. Microtensile bond strengths were tested and the mean bond strengths (MPa) were 18.81 for Cont. group, 23.65 for Low-UV group, 34.75 for High-UV group. UV irradiation had a significant effect on the bond strength (p<0.05). UV irradiation demonstrates its capability to improve the bond strength between epoxy-based glass fiber posts and resin cement.

  9. Acute severe male hypo-testosteronemia affects central motor command in humans.

    PubMed

    Felici, Francesco; Bazzucchi, Ilenia; Sgrò, Paolo; Quinzi, Federico; Conti, Alessandra; Aversa, Antonio; Gizzi, Leonardo; Mezzullo, Marco; Romanelli, Francesco; Pasquali, Renato; Lenzi, Andrea; Di Luigi, Luigi

    2016-06-01

    To indirectly evaluate the effect of androgens on neuromuscular system in humans we analyzed if an induced short-term hypogonadal state (serum total testosterone-TT<2.3ng/ml) may affect central drive to skeletal muscle and/or muscle neuro-mechanical performance. We compared voluntary and electrically evoked muscle sEMG signals from biceps brachii in nine hypogonadal male volunteers (Hypo) and in ten healthy controls (Cont). Serum TT and dihydrotestosterone (DHT) were assayed. With respect to Hypo, Cont exhibited significantly higher median frequency content (MDF) at any angular velocity; normalized MDF [95.9% (SD=23.3) vs 73.8% (SD=9.3)]; muscle fiber conduction velocity (CV) from lowest to highest angular velocities; initial MDF at fatigue test [91.78Hz (SD=22.03) vs 70.94Hz (SD=11.06)] as well as was the normalized slope [-0.64 (SD=0.14 vs -0.5 (SD=0.11)]. In the non-fatigued state, Hypo showed a slower single twitches time to peak (TTP). In Cont, half relaxation time (HRT) decreased after fatigue while increased in Hypo (p<0.05 between groups). A significant correlation between both TT and dihydrotestosterone with MDF and CV was found during voluntary contractions only. A brief exposure to very low serum TT concentration in males seem to determine a reduced excitability of the NM system which, in turn, would favor a predominant recruitment of slow twitch MUs. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Vitamin D receptor levels in colorectal cancer. Possible role of BsmI polymorphism.

    PubMed

    Parisi, Eva; Reñé, Josep Maria; Cardús, Anna; Valcheva, Petya; Piñol-Felis, Carme; Valdivielso, José Manuel; Fernández, Elvira

    2008-07-01

    A high expression of vitamin D receptor (VDR) in colorectal cancer (CRC) tumoral tissue has been related to a good prognosis and it has been proposed that it could be a good biological marker of CRC progression. Nevertheless, there are no previous studies that compare the VDR expression in tumoral towards normal tissue of the same CRC patient in relation to VDR BsmI genotype. We collected normal and tumoral tissue samples, as well as blood samples, from CRC patients (n=170) and controls (n=122). VDR genotyping was performed and BsmI homozygous patients were selected (CRC=50, Cont=32). VDR mRNA and protein levels were analyzed. We also measured 25-Hydroxyvitamin D serum levels. We found no differences in the polymorphism distribution in tumoral versus normal tissue (control: BB=15.7%, bb=41.3%, Bb=43%; CRC: BB=14.2%, bb=41.9%, Bb=43.9%). Furthermore, VDR levels decreased in colonic cancer tissue (mean: 3.03) versus normal mucosa (11.62) from the same patient (p<0.001), but this decrease was similar in both genotypes. There were differences in 25-Hydroxyvitamin D(3) levels between the CRC and the control group (CRC=8.65 ng/ml, Cont=18.15 ng/ml). In conclusion, we found a decrease in VDR levels in tumoral compared with normal mucosa from the same patient. This difference is independent of the BsmI polymorphism.

  11. Induced molt using cassava meal. 2. Effects on eggshell quality, ultrastructure, and pore density in late-phase laying hens.

    PubMed

    Gongruttananun, N

    2018-03-01

    This experiment was conducted to investigate the effect of a non-fasting induced molt using cassava meal on the eggshell quality, ultrastructure, and porosity in late-phase (74 wk old) H&N Brown laying hens. Hens were randomly assigned to 3 treatments of 90 birds each: 1) Controls with no induced molt (CONT); 2) molted by full feeding with cassava meal for 3 wk (FP3); and 3) molted by full feeding with cassava meal for 4 wk (FP4). Following the treatments, groups 2 and 3 were fed a pullet developer diet for 3 weeks. During the molt period, the birds were exposed to an 8L:16D photoperiod and had access to drinking water at all times. Thereafter, all hens were fed a layer diet (17% CP) and exposed to a 16L:8D photoperiod until the end of the study. Compared to the CONT treatment, significant reductions (P < 0.05) in shell weight, thickness, and breaking strength were identified on the sixth d of feeding the molt diet. Significant (P < 0.05) improvements in these parameters were observed for the FP3 and FP4 treatments during the post-molt period, with the greater degree in the FP4 treatment. In addition, scanning electron microscopy revealed a smaller size of mammillary knobs accompanied by a higher density of mammillae in eggs taken from the molted treatments. Evidence of type B mammillae was detected in an egg produced by the CONT hens, whereas confluent and cuffing mammillae were observed in an egg taken from the FP4 birds. Reduced pore densities were found in the molted treatments in some periods of the post-molt production as compared to the CONT treatment. It was concluded that feeding the cassava molt diet for 4 wk could be an effective non-fasting molt method for improving eggshell quality, ultrastructure, and porosity in post-molt laying hens.

  12. Cont-Bouchaud Percolation Model Including Tobin Tax

    NASA Astrophysics Data System (ADS)

    Ehrenstein, Gudrun

    The Tobin tax is an often discussed method to tame speculation and get a source of income. The discussion is especially heated when the financial markets are in crisis. In this article we refer to the foreign exchange markets. The Tobin tax should be a small international tax affecting all currency transactions and thus consequently reducing destabilizing speculations. In this way this tax should take over a control function. By including the Tobin tax in the microscopic model of Cont and Bouchaud one finds that this tax could be the right method to control foreign exchange operations and to get a good source of income.

  13. Does haptic steering guidance instigate speeding? A driving simulator study into causes and remedies.

    PubMed

    Melman, T; de Winter, J C F; Abbink, D A

    2017-01-01

    An important issue in road traffic safety is that drivers show adverse behavioral adaptation (BA) to driver assistance systems. Haptic steering guidance is an upcoming assistance system which facilitates lane-keeping performance while keeping drivers in the loop, and which may be particularly prone to BA. Thus far, experiments on haptic steering guidance have measured driver performance while the vehicle speed was kept constant. The aim of the present driving simulator study was to examine whether haptic steering guidance causes BA in the form of speeding, and to evaluate two types of haptic steering guidance designed not to suffer from BA. Twenty-four participants drove a 1.8m wide car for 13.9km on a curved road, with cones demarcating a single 2.2m narrow lane. Participants completed four conditions in a counterbalanced design: no guidance (Manual), continuous haptic guidance (Cont), continuous guidance that linearly reduced feedback gains from full guidance at 125km/h towards manual control at 130km/h and above (ContRF), and haptic guidance provided only when the predicted lateral position was outside a lateral bandwidth (Band). Participants were familiarized with each condition prior to the experimental runs and were instructed to drive as they normally would while minimizing the number of cone hits. Compared to Manual, the Cont condition yielded a significantly higher driving speed (on average by 7km/h), whereas ContRF and Band did not. All three guidance conditions yielded better lane-keeping performance than Manual, whereas Cont and ContRF yielded lower self-reported workload than Manual. In conclusion, continuous steering guidance entices drivers to increase their speed, thereby diminishing its potential safety benefits. It is possible to prevent BA while retaining safety benefits by making a design adjustment either in lateral (Band) or in longitudinal (ContRF) direction. Copyright © 2016. Published by Elsevier Ltd.

  14. Effect of Gallic Acid on Dementia Type of Alzheimer Disease in Rats: Electrophysiological and Histological Studies.

    PubMed

    Hajipour, Somayeh; Sarkaki, Alireza; Farbood, Yaghoob; Eidi, Akram; Mortazavi, Pejman; Valizadeh, Zohreh

    2016-04-01

    To study the effect of gallic acid (GA) on hippocampal long-term potentiation (LTP) and histological changes in animal model of Alzheimer disease (AD) induced by beta-amyloid (Aβ). Sixty-four adult male Wistar rats (300±20 g) were divided into 8 groups: 1) Control (Cont); 2) AD; 3) Sham; 4-7) AD+GA (50, 100, and 200 mg/kg for 10 days, orally) or vehicle, 8) Cont+GA100, Aβ (1μg/μL in each site) was infused into hippocampus bilaterally. Changes of amplitude and slope of LTP induced in hippocampal dentate gyrus (DG) were evaluated by high frequency stimulation (HFS) of perforant path (PP). Data showed that LTP amplitude and area under curve significantly impaired in AD rats (P<0.001), while significantly improved in AD rats treated with GA (P<0.05, P<0.01). Current findings suggest that GA reduces neural damage and brain amyloid neuropathology and improves cognitive function via free radicals scavenging and inhibiting oligomerization of Aβ but with no effect on healthy rats.

  15. From CONT to VGOS: the Evolution of the CONT Campaigns

    NASA Astrophysics Data System (ADS)

    Thomas, Cynthia C.; Behrend, Dirk; MacMillan, Daniel S.

    2016-12-01

    Continuous VLBI campaigns (CONT) started in 1994 with the goal of demonstrating state-of-the-art VLBI over a continuous period of time. The first CONT was followed by campaigns in 1995 and 1996. After a six year hiatus, CONT campaigns were organized approximately every three years from 2002 through 2014. In this paper we primarily focus on the cornerstones of each CONT campaign. Specifically, we review the developments in networks, scheduling techniques, recording media, correlation, and other resources used. A timeline of the history of the CONTs and the goals for future campaigns will be presented. The CONTs used a significant amount of IVS resources to produce a large volume of high quality data and demonstrated the advantages of continuous observing which will soon be realized with VGOS.

  16. Cold-water immersion decreases cerebral oxygenation but improves recovery after intermittent-sprint exercise in the heat.

    PubMed

    Minett, G M; Duffield, R; Billaut, F; Cannon, J; Portus, M R; Marino, F E

    2014-08-01

    This study examined the effects of post-exercise cooling on recovery of neuromuscular, physiological, and cerebral hemodynamic responses after intermittent-sprint exercise in the heat. Nine participants underwent three post-exercise recovery trials, including a control (CONT), mixed-method cooling (MIX), and cold-water immersion (10 °C; CWI). Voluntary force and activation were assessed simultaneously with cerebral oxygenation (near-infrared spectroscopy) pre- and post-exercise, post-intervention, and 1-h and 24-h post-exercise. Measures of heart rate, core temperature, skin temperature, muscle damage, and inflammation were also collected. Both cooling interventions reduced heart rate, core, and skin temperature post-intervention (P < 0.05). CWI hastened the recovery of voluntary force by 12.7 ± 11.7% (mean ± SD) and 16.3 ± 10.5% 1-h post-exercise compared to MIX and CONT, respectively (P < 0.01). Voluntary force remained elevated by 16.1 ± 20.5% 24-h post-exercise after CWI compared to CONT (P < 0.05). Central activation was increased post-intervention and 1-h post-exercise with CWI compared to CONT (P < 0.05), without differences between conditions 24-h post-exercise (P > 0.05). CWI reduced cerebral oxygenation compared to MIX and CONT post-intervention (P < 0.01). Furthermore, cooling interventions reduced cortisol 1-h post-exercise (P < 0.01), although only CWI blunted creatine kinase 24-h post-exercise compared to CONT (P < 0.05). Accordingly, improvements in neuromuscular recovery after post-exercise cooling appear to be disassociated with cerebral oxygenation, rather reflecting reductions in thermoregulatory demands to sustain force production. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. New Curculionoidea (Coleoptera) records for Quebec, Canada

    PubMed Central

    de Tonnancour, Pierre; Anderson, Robert S.; Bouchard, Patrice; Chantal, Claude; Dumont, Stéphane; Vigneault, Robert

    2017-01-01

    Abstract The following species of Curculionoidea are newly recorded from the Canadian province of Quebec: Coelocephalapion emaciipes (Fall, 1898); Ischnopterapion virens (Herbst, 1797); Omphalapion hookerorum (Kirby, 1808); Perapion punctinasum (J.B. Smith, 1884) (all Brentidae); Anthonomus robustulus LeConte, 1876; Pseudanthonomus helvolus (Boheman, 1843); Bagous magister LeConte, 1876; Bagous tanneri O’Brien, 1979; Buchananius striatus (LeConte, 1876); Ceutorhynchus bolteri Dietz, 1896; Ceutorhynchus pallidactylus (Marsham, 1802); Ceutorhynchus pauxillus Dietz, 1896; Conotrachelus buchanani Schoof, 1942; Conotrachelus pusillus LeConte, 1878; Conotrachelus recessus (Casey, 1910); Curculio rubidus (Gyllenhal, 1835); Cylindrocopturus longulus (LeConte, 1876); Hadroplontus litura (Fabricius, 1775); Hypera rumicis (Linnaeus, 1758); Lixus terminalis LeConte, 1876; Myosides seriehispidus Roelofs, 1873; Phloeotribus dentifrons (Blackman, 1921); Plocamus echidna (LeConte, 1876); Scolytus muticus Say, 1824; Sirocalodes sericans (LeConte, 1876); Smicronyx sculpticollis Casey, 1892 (all Curculionidae). Among these, Buchananius striatus, Conotrachelus buchanani, Conotrachelus pusillus, and Curculio rubidus (all Curculionidae) are also recorded from Canada for the first time. The latter is also newly reported from Ontario. Collecting data are provided for Lixus punctinasus LeConte, 1876, previously reported to occur in Canada without any further information, and for Choragus sayi LeConte, 1876 (Anthribidae) and Rhyssomatus aequalis Horn, 1873 (Curculionidae), both previously recorded from Quebec, also without further details. PMID:28769721

  18. Acute Oral Toxicity (LD(50)) of CHF1 in Rats.

    DTIC Science & Technology

    1982-04-01

    had moderate hydronephrosis . Another animal in group 6 and one in group 4 had gray streaks in the cortical parenchyma which were probably incidental...considered to be a post mortem change. *Number of rats affected/number of rats in the group. 21 APPENDIX A-2 (cont.) Unilateral hydronephrosis was observed in

  19. Peripheral artery bypass - leg

    MedlinePlus

    ... nih.gov/pubmed/23473760 . Society for Vascular Surgery Lower Extremity Guidelines Writing Group; Conte MS, Pomposelli FB, et ... practice guidelines for atherosclerotic occlusive disease of the ... management of asymptomatic disease and claudication. J Vasc ...

  20. Should drivers be operating within an automation-free bandwidth? Evaluating haptic steering support systems with different levels of authority.

    PubMed

    Petermeijer, Sebastiaan M; Abbink, David A; de Winter, Joost C F

    2015-02-01

    The aim of this study was to compare continuous versus bandwidth haptic steering guidance in terms of lane-keeping behavior, aftereffects, and satisfaction. An important human factors question is whether operators should be supported continuously or only when tolerance limits are exceeded. We aimed to clarify this issue for haptic steering guidance by investigating costs and benefits of both approaches in a driving simulator. Thirty-two participants drove five trials, each with a different level of haptic support: no guidance (Manual); guidance outside a 0.5-m bandwidth (Band1); a hysteresis version of Band1, which guided back to the lane center once triggered (Band2); continuous guidance (Cont); and Cont with double feedback gain (ContS). Participants performed a reaction time task while driving. Toward the end of each trial, the guidance was unexpectedly disabled to investigate aftereffects. All four guidance systems prevented large lateral errors (>0.7 m). Cont and especially ContS yielded smaller lateral errors and higher time to line crossing than Manual, Band1, and Band2. Cont and ContS yielded short-lasting aftereffects, whereas Band1 and Band2 did not. Cont yielded higher self-reported satisfaction and faster reaction times than Band1. Continuous and bandwidth guidance both prevent large driver errors. Continuous guidance yields improved performance and satisfaction over bandwidth guidance at the cost of aftereffects and variability in driver torque (indicating human-automation conflicts). The presented results are useful for designers of haptic guidance systems and support critical thinking about the costs and benefits of automation support systems.

  1. BIOAVAILABILITY OF MERCURY IN SEDIMENTS FROM A FLOOD CONTROL RESERVOIR TO HYALELLA AZTECA

    EPA Science Inventory

    In the last three years, mercury contamination in North Mississippi flood control reservoirs has become a growing concern. Previous data indicate that three flood control reservoirs have similar total mercury sediment concentrations and that fish collected from one reservoir cont...

  2. New Curculionoidea (Coleoptera) records for Canada

    PubMed Central

    Douglas, Hume; Bouchard, Patrice; Anderson, Robert S.; de Tonnancour, Pierre; Vigneault, Robert; Webster, Reginald P.

    2013-01-01

    Abstract The following species of Curculionoidea are recorded from Canada for the first time, in ten cases also representing new records at the generic level: Ischnopterapion (Ischnopterapion) loti (Kirby, 1808); Stenopterapion meliloti (Kirby, 1808) (both Brentidae); Atrichonotus taeniatulus (Berg, 1881); Barinus cribricollis (LeConte, 1876); Caulophilus dubius (Horn, 1873); Cionus scrophulariae (Linnaeus, 1758); Cryptorhynchus tristis LeConte, 1876; Cylindrocopturus furnissi Buchanan, 1940; Cylindrocopturus quercus (Say, 1832); Desmoglyptus crenatus (LeConte, 1876); Pnigodes setosus LeConte, 1876; Pseudopentarthrum parvicollis (Casey, 1892); Sibariops confinis (LeConte, 1876); Sibariops confusus (Boheman, 1836); Smicronyx griseus LeConte, 1876; Smicronyx lineolatus Casey, 1892; Euwallacea validus (Eichhoff, 1875); Hylocurus rudis (LeConte, 1876); Lymantor alaskanus Wood, 1978; Phloeotribus scabricollis (Hopkins, 1916); Scolytus oregoni Blackman, 1934; Xyleborus celsus Eichhoff, 1868; Xyleborus ferrugineus (Fabricius, 1801); Xylosandrus crassiusculus (Motschulsky, 1866) (all Curculionidae). In addition the following species were recorded for the first time from these provinces and territories: Yukon – Dendroctonus simplex LeConte, 1868; Phloetribus piceae Swaine, 1911 (both Curculionidae); Northwest Territories – Loborhynchapion cyanitinctum (Fall, 1927) (Brentidae); Nunavut – Dendroctonus simplex LeConte, 1868 (Curculionidae); Alberta – Anthonomus tectus LeConte, 1876; Promecotarsus densus Casey, 1892; Dendroctonus ponderosae Hopkins, 1902; Hylastes macer LeConte, 1868; Rhyncolus knowltoni (Thatcher, 1940); Scolytus schevyrewi Semenov Tjan-Shansky, 1902 (all Curculionidae); Saskatchewan – Phloeotribus liminaris (Harris, 1852); Rhyncolus knowltoni (Thatcher, 1940); Scolytus schevyrewi Semenov Tjan-Shansky, 1902 (all Curculionidae); Manitoba – Cosmobaris scolopacea Germar, 1819; Listronotus maculicollis (Kirby, 1837); Listronotus punctiger LeConte, 1876; Scolytus schevyrewi Semenov Tjan-Shansky, 1902; Tyloderma foveolatum (Say, 1832); (all Curculionidae); Ontario – Trichapion nigrum (Herbst, 1797); Nanophyes marmoratus marmoratus (Goeze, 1777) (both Brentidae); Asperosoma echinatum (Fall, 1917); Micracis suturalis LeConte, 1868; Orchestes alni (Linnaeus, 1758); Phloeosinus pini Swaine, 1915; Scolytus schevyrewi Semenov Tjan-Shansky, 1902; Xyleborinus attenuatus (Blandford, 1894) (all Curculionidae); Quebec – Trigonorhinus alternatus (Say, 1826); Trigonorhinus tomentosus tomentosus (Say, 1826) (both Anthribidae); Trichapion nigrum (Herbst, 1797); Trichapion porcatum (Boheman, 1839); Nanophyes marmoratus marmoratus (Goeze, 1777) (all Brentidae); Lissorhoptrus oryzophilus Kuschel, 1952 (Brachyceridae); Acalles carinatus LeConte, 1876; Ampeloglypter ampelopsis (Riley, 1869); Anthonomus rufipes LeConte, 1876; Anthonomus suturalis LeConte, 1824; Ceutorhynchus hamiltoni Dietz, 1896; Curculio pardalis (Chittenden, 1908); Cyrtepistomus castaneus (Roelofs, 1873); Larinus planus (Fabricius, 1792); Mecinus janthinus (Germar, 1821); Microhyus setiger LeConte, 1876; Microplontus campestris (Gyllenhal, 1837); Orchestes alni (Linnaeus, 1758); Otiorhynchus ligustici (Linnaeus, 1758); Rhinusa neta (Germar, 1821); Trichobaris trinotata (Say, 1832); Tychius liljebladi Blatchley, 1916; Xyleborinus attenuatus (Blandford, 1894); Xyleborus affinis Eichhoff, 1868 (all Curculionidae); Sphenophorus incongruus Chittenden, 1905 (Dryophthoridae); New Brunswick – Euparius paganus Gyllenhal, 1833; Allandrus populi Pierce, 1930; Gonotropis dorsalis (Thunberg, 1796); Euxenus punctatus LeConte, 1876 (all Anthribidae); Loborhynchapion cyanitinctum (Fall, 1927) (Brentidae); Pseudanthonomus seriesetosus Dietz, 1891; Curculio sulcatulus (Casey, 1897); Lignyodes bischoffi (Blatchley, 1916); Lignyodes horridulus (Casey, 1892); Dietzella zimmermanni (Gyllenhal, 1837); Parenthis vestitus Dietz, 1896; Pelenomus squamosus LeConte, 1876; Psomus armatus Dietz, 1891; Rhyncolus macrops Buchanan, 1946; Magdalis inconspicua Horn, 1873; Magdalis salicis Horn, 1873 (all Curculionidae); Nova Scotia – Dryocoetes autographus (Ratzeburg, 1837); Ips perroti Swaine, 1915; Xyleborinus attenuatus (Blandford, 1894) (all Curculionidae); Prince Edward Island – Dryocoetes caryi Hopkins, 1915 (Curculionidae); Newfoundland – Scolytus piceae (Swaine, 1910) (Curculionidae). Published records of Dendroctonus simplex LeConte, 1868 from Northwest Territories should be reassigned to Nunavut, leaving no documented record for NWT. Collection data are provided for eight provincial and national records published without further information previously. PMID:23794927

  3. C-Myc Induced Compensated Cardiac Hypertrophy Increases Free Fatty Acid Utilization for the Citric Acid Cycle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olson, Aaron; Ledee, Dolena; Iwamoto, Kate

    The protooncogene C-Myc (Myc) regulates cardiac hypertrophy. Myc promotes compensated cardiac function, suggesting that the operative mechanisms differ from those leading to heart failure. Myc regulation of substrate metabolism is a reasonable target, as Myc alters metabolism in other tissues. We hypothesize that Myc-induced shifts in substrate utilization signal and promote compensated hypertrophy. We used cardiac specific Myc-inducible C57/BL6 male mice between 4-6 months old that develop hypertrophy with tamoxifen (tam). Isolated working hearts and 13Carbon (13C )-NMR were used to measure function and fractional contributions (Fc) to the citric acid cycle by using perfusate containing 13C-labeled free fatty acids,more » acetoacetate, lactate, unlabeled glucose and insulin. Studies were performed at pre-hypertrophy (3-days tam, 3dMyc), established hypertrophy (7-days tam, 7dMyc) or vehicle control (cont). Non-transgenic siblings (NTG) received 7-days tam or vehicle to assess drug effect. Hypertrophy was confirmed by echocardiograms and heart weights. Western blots were performed on key metabolic enzymes. Hypertrophy occurred in 7dMyc only. Cardiac function did not differ between groups. Tam alone did not affect substrate contribution in NTG. Substrate utilization was not significantly altered in 3dMyc versus cont. The free fatty acid FC was significantly greater in 7dMyc vs cont with decreased unlabeled Fc, which is predominately exogenous glucose. Free fatty acid flux to the citric acid cycle increased while lactate flux was diminished in 7dMyc compared to cont. Total protein levels of a panel of key metabolic enzymes were unchanged; however total protein O-GlcNAcylation was increased in 7dMyc. Substrate utilization changes did not precede hypertrophy; therefore they are not the primary signal for cardiac growth in this model. Free fatty acid utilization and oxidation increase at established hypertrophy. Understanding the mechanisms whereby this change maintained compensated function could provide useful information for developing metabolic therapies to treat heart failure. The molecular signaling for this metabolic change may occur through O-GlcNAcylation.« less

  4. Influence of de/remineralization of enamel on the tensile bond strength of etch-and-rinse and self-etching adhesives.

    PubMed

    Farias de Lacerda, Ana Julia; Ferreira Zanatta, Rayssa; Crispim, Bruna; Borges, Alessandra Bühler; Gomes Torres, Carlos Rocha; Tay, Franklin R; Pucci, Cesar Rogério

    2016-10-01

    To evaluate the bonding behavior of resin composite and different adhesives applied to demineralized or remineralized enamel. Bovine tooth crowns were polished to prepare a 5 mm2 enamel bonding area, and divided into five groups (n= 48) according to the surface treatment: CONT (sound enamel control), DEM (demineralized with acid to create white spot lesions), REMS (DEM remineralized with artificial saliva), REMF (DEM remineralized with sodium fluoride) and INF (DEM infiltrated with Icon resin infiltrant). The surface-treated teeth were divided into two subgroups (n= 24) according to adhesive type: ER (etch-and-rinse; Single Bond Universal) and SE (self-etching; Clearfill S3 Bond), and further subdivided into two categories (n= 12) according to aging process: Thermo (thermocycling) and NA (no aging). Composite blocks were made over bonded enamel and sectioned for microtensile bond strength (MTBS) testing. Data were analyzed with three-way ANOVA and post-hoc Tukey's test (α= 0.05). Significant differences were observed for enamel surface treatment (P< 0.0001), adhesive type (P< 0.0001) and aging (P< 0.0001). CONT and INF groups had higher MTBS than the other groups; Single Bond Universal had higher MTBS than Clearfil S3 Bond; thermo-aging resulted in lower MTBS irrespective of adhesive type and surface treatment condition. The predominant failure mode was mixed for all groups. Enamel surface infiltrated with Icon does not interfere with adhesive resin bonding procedures. Treatment of enamel surface containing white spot lesions or cavities with cavosurface margins in partially-demineralized enamel can benefit from infiltration with a low viscosity resin infiltrant prior to adhesive bonding of resin composites.

  5. Long-term betacarotene-supplementation enhances serum insulin concentrations without effect on the onset of puberty in the female goat.

    PubMed

    Meza-Herrera, Cesar A; Hernández-Valenzuela, Luis C; González-Bulnes, Antonio; Tena-Sempere, Manuel; Abad-Zavaleta, Jose; Salinas-Gonzalez, Homero; Mellado, Miguel; Veliz-Deras, Francisco

    2011-11-01

    The effect of betacarotene (BC) supplementation on the onset of puberty and serum insulin levels in goats was evaluated in the study. In June, prepuberal goats (n=17; 3 months old; 7/8 Saanen-Alpine; 26° NL) were randomly assigned to one of two groups: 1/ betacarotene group supplemented daily with 50 mg of BC (n=9; live weight [LW]: 17.3±1.0 kg; body condition score [BCS]: 3.34±0.12) or 2/ control group (CONT; n=8; LW:16.1±1.0 kg; BCS=3.17±0.12). From June to November, an intermittent blood sampling was performed twice per week in both groups to evaluate serum progesterone (P(4)), while monthly samples were intended for insulin (INS) determination. Initial mean LW (16.7±1.0 kg) and BCS (3.31±0.12) were similar (p>0.05) in both groups. Mean serum insulin (1.37 vs. 1.18±0.09 ng/ml), age of puberty (215.7 vs. 226.5±6.6 days) and the percentage of goats reaching puberty (44.4 vs. 25.0±17.0%) did not differ (p>0.05) between BC and CONT group, respectively. However, increase in serum insulin during the second half of the experiment was observed in BC group (p<0.05) which was positively correlated with LW (r=0.95; p<0.05). In addition, as LW (r=-0.89) and serum insulin (r=-0.76) levels increased, the natural photoperiod decreased, revealing negative correlations (p<0.05) between the respective variables. In this study, BC supplementation did not promote precocious puberty and did not affect the percentage of goats reaching activation of the hypothalamic-hypophyseal-gonadal axis during the establishment of puberty. Nonetheless, BC supplementation positively affected the release pattern of insulin suggesting a potential role of BC as pancreas-activating molecule.

  6. Effectiveness of urban stormwater control measures in a 100-acre test site

    EPA Science Inventory

    Kansas City, Missouri chose a test area (100 acres) and a control area (80 acres) to test the effectiveness of urban stormwater control (SCM) deployment in conjunction with the USEPA, University of Alabama, University of Missouri-Kansas City and TetraTech. Both the test and cont...

  7. Primary Attraction of Ips latidens (LeConte) and Hylastes Gracilis LeConte (Coleoptera: Scolytidae) to High-Girdled Lodgepole Pine, Pinus Contorta var. Latifolia Engelmann

    Treesearch

    D.R. Miller; J.L. Madden; J.H. Borden

    1986-01-01

    In the absence of secondary attraction, 2 species of Scolytidae, Ips latidens (LeConte) and Hylastes gracilis LeConte, showed significant preference while in flight for high-girdled over non-girdled lodgepole pines, Pinus contorta var. latifolia Engelmann. In contrast, beetles in 2 genera...

  8. An Evaluation Method for Suppression of Pathogenic Fusarium oxysporum by Soil Microorganisms Using the Dilution Plate Technique.

    PubMed

    Mitsuboshi, Masahiro; Kioka, Yuuzou; Noguchi, Katsunori; Asakawa, Susumu

    2017-01-01

    Volume 31, No. 3, Page 307-313, 2016Page 310, Legend for Fig. 4 IncorrectFig. 4. Growth degree of Fusarium oxysporum f. sp. spinaciae for organic fertilizers at each dilution based on an estimation of the ellipse area (A) and extension length (B) of the colony. Cont, compound inorganic fertilizer; SBM, steamed bone meal; CDC, cow dung compost; MI, microbial inoculant. Values show mean of medians of degrees with SE (n=3). The ellipse area and extension length for control plates were 4,475 mm 2 and 36.5 mm, respectively. CorrectFig. 4. Growth degree of Fusarium oxysporum f. sp. spinaciae for organic fertilizers at each dilution based on an estimation of the ellipse area (A) and extension length (B) of the colony. Cont, compound inorganic fertilizer; SBM, steamed bone meal; CDC, cow dung compost; MI, microbial inoculant. Values show mean of growth degrees with SE (n=3). The ellipse area and extension length for control plates were 4,475 mm 2 and 36.5 mm, respectively. Page 311, Legend for Fig. 5 IncorrectFig. 5. Growth degree of Fusarium oxysporum f. sp. spinaciae for soil applied with organic fertilizers at each dilution based on an estimation of the ellipse area (A) and extension length (B) of the colony. Cont, compound inorganic fertilizer; SBM, steamed bone meal; CDC, cow dung compost; MI, microbial inoculant. Values show the mean of medians of degrees with SE (n=3). The ellipse area and extension length for control plates were 5,473 mm 2 and 40.5 mm, respectively. CorrectFig. 5. Growth degree of Fusarium oxysporum f. sp. spinaciae for soil applied with organic fertilizers at each dilution based on an estimation of the ellipse area (A) and extension length (B) of the colony. Cont, compound inorganic fertilizer; SBM, steamed bone meal; CDC, cow dung compost; MI, microbial inoculant. Values show the mean of growth degrees with SE (n=3). The ellipse area and extension length for control plates were 5,473 mm 2 and 40.5 mm, respectively. Page 312, Legend for Fig. 7 IncorrectFig. 7. Growth degree of Fusarium oxysporum f. sp. spinaciae at each dilution based on an estimation of the ellipse area (A) and extension length (B) of the colony. Cont, compound inorganic fertilizer; SBM, steamed bone meal; CDC, cow dung compost; MI2, microbial inoculant applied with 2,000 kg ha -1 ; MI10, microbial inoculant applied with 10,000 kg ha -1 . Values show the mean of medians of degrees with SE (n=3). The ellipse area and extension length for control plates were 3,404 mm 2 and 29.7 mm, respectively. CorrectFig. 7. Growth degree of Fusarium oxysporum f. sp. spinaciae at each dilution based on an estimation of the ellipse area (A) and extension length (B) of the colony. Cont, compound inorganic fertilizer; SBM, steamed bone meal; CDC, cow dung compost; MI2, microbial inoculant applied with 2,000 kg ha -1 ; MI10, microbial inoculant applied with 10,000 kg ha -1 . Values show the mean of growth degrees with SE (n=3). The ellipse area and extension length for control plates were 3,404 mm 2 and 29.7 mm, respectively. The authors would like to apologize for these corrections and any inconvenience caused.

  9. The effect of dietary supplementation with the natural carotenoids curcumin and lutein on pigmentation, oxidative stability and quality of meat from broiler chickens affected by a coccidiosis challenge.

    PubMed

    Rajput, N; Ali, S; Naeem, M; Khan, M A; Wang, T

    2014-01-01

    1. An experiment was performed to evaluate the effectiveness of the antioxidants curcumin (CRM) and lutein (LTN) on the quality of meat from coccidiosis-infected broilers. A total of 200 one-day-old Arbor Acre chicks were randomly assigned to a treatment group with 5 replicates. The treatments included a basal diet without carotenoid supplementation (control), with 300 mg/kg CRM, with 300 mg/kg LTN or with a combination (C + L) of 150 mg/kg CRM and 150 mg/kg LTN. All chickens were challenged with Eimeria maxima at 21 d old. 2. The results revealed that the coccidiosis reduced redness of meat, while supplementation with carotenoids improved the fresh meat's redness (a*) and yellowness (b*) and contributed to colour stability maintenance after storage (1 month at -18°C and 3 d at 4°C). 3. Coccidiosis did not produce lipid and protein oxidation in fresh meat, but after storage for one month, the malondialdehyde levels and carbonyl contents were lower in the CRM and C + L birds and the sulfhydryl contents were higher in C + L birds. 4. The sodium dodecyl sulphate-polyacrylamide gel electrophoresis banding pattern showed equivalent myosin chain fragmentations in all treatment groups, whereas lower intensity actin bands were observed in the control group (CONT). Moreover, myofibril protein denaturation (differential scanning calorimetry) profiles showed a reduction in the CONT myosin and actin peaks. Coccidiosis reduced the meat's water holding capacity in non-supplemented chicken meat and was improved by natural carotenoid. 5. These results emphasise that coccidiosis did not decrease the eating quality of fresh meat, that natural carotenoids are efficient antioxidants and that CRM (300 mg/kg) fed individually or combined with LTN was the most effective supplemented antioxidant compound.

  10. Anxiety among individuals with visual vertigo and vestibulopathy.

    PubMed

    Zur, Oz; Schoen, Gila; Dickstein, Ruth; Feldman, Jacob; Berner, Yitshal; Dannenbaum, Elizabeth; Fung, Joyce

    2015-01-01

    Visual vertigo (VV) is a type of dizziness triggered by visual stimuli. Despite a high incidence, its relationship with anxiety is not well-defined or understood. This study evaluated anxiety levels in subjects with VV compared to vestibulopathic subjects without VV and healthy individuals. A cross-sectional study to evaluate anxiety among individuals with VV was conducted twice. The first study included 72 participants (66 to 83 years of age) from senior residential centers. The second included 31 participants from a vestibular rehabilitation program (age range 35-82 years). Study 1 also used the Activities-Specific Balance Confidence (ABC) scale and study 2 the Dizziness Handicap Inventory (DHI). Subjects were classified as VV positive (27 in study 1, 10 in study 2) or vestibulopathic without VV (30 in study 1, 11 in study 2) based on Head Impulse or Dynamic Visual Acuity Tests and the Dizziness Questionnaire. The remaining were age-matched healthy controls. The outcome of each study demonstrated significantly higher anxiety levels (p = 0.0001) in the VV group compared to the other groups. The results of the ABC test demonstrated that subjects in the VV group had significantly lower self-confidence (p = 0.001) than those in the Vest and Cont groups and performed fewer balance-related activities of daily life. DHI results showed that VV group expressed higher (p < 0.001) mean scores for self-perceived feelings of dizziness and imbalance (54%), compared to the Vest (9%) and Cont groups (1%). Anxiety related to VV requires special attention when assessing and managing vestibulopathy, regardless of patient age. Anxiety is a characteristic of subjects with visual vertigo (VV) and vestibulopathy. Anxiety in subjects with VV is not related to age. VV should be considered when subjects with anxiety complain of imbalance. Anxiety and vestibulopathy are often interrelated and should be considered in diagnostic evaluations.

  11. The embryological development of primary visual centres in the turtle Emys orbicularis.

    PubMed Central

    Hergueta, S; Lemire, M; Pieau, C; Ward, R; Repérant, J

    1993-01-01

    The development of the primary visual centres was studied in a series of embryos of the turtle, Emys orbicularis, incubated at 25 degrees C. The differentiation of both visual and nonvisual diencephalic and mesencephalic structures takes place entirely within the 2nd quarter of the period of incubation; this finding appears to be consistent with previous descriptions of the embryology of 2 other chelonian species, Lepidochelys and Chelydra. Two successive waves of migration, each dividing into internal and external sheaves, are involved in the formation of the structures of the diencephalon and mesencephalon. The primary visual centres, which comprise 2 hypothalamic, 5 thalamic and 5 pretectal zones of retinal projections, together with the 2 superficial layers of the tectum and a single tegmental projection zone, all have their origin in the external sheaf of the 1st wave of migration. The finding that the adult nucleus geniculatus lateralis dorsalis, pars ventralis arises from one of the migrations of the dorsal thalamus is discussed in the context of the debate over the possible homologues of the mammalian geniculostriate visual pathway. Images Fig. 1 (cont.) Fig. 1 Fig. 2 (cont.) Fig. 2 Fig. 3 (cont.) Fig. 3 Fig. 4 (cont.) Fig. 4 Fig. 5 (cont.) Fig. 5 Fig. 6 (cont.) Fig. 6 Fig. 7 Fig. 8 (cont.) Fig. 8 Fig. 9 (cont.) Fig. 9 Fig. 10 (cont.) Fig. 10 Fig. 11 Fig. 12 Fig. 13 Fig. 14 PMID:8300423

  12. Repeat Effort Performance is Reduced 24 h following Acute Dehydration in Mixed Martial Arts Athletes.

    PubMed

    Barley, Oliver R; Iredale, Fiona; Chapman, Dale W; Hopper, Amanda; Abbiss, Chris

    2017-09-11

    This study sought to determine the influence of acute dehydration on physical performance and physiology in Mixed Martial Arts (MMA). MMA athletes (n=14; age: 23±4 years), completed in a randomised counterbalanced order a dehydration protocol, (DHY: 3 h cycling at 60 W in 40°C to induce 5% dehydration) or thermoneutral control (25°C: CONT) exercise, followed by ad libitum fluid/food intake. Performance testing (a repeat sled push test, medicine ball chest throw and vertical jump) was completed 3 and 24 h following the intervention, while urine and blood samples were collected before, 20 min, 3 and 24 h following the intervention. Body mass was reduced (4.8±0.8%) following DHY (p<0.001) and remained lower than CONT at 3 and 24 h post (p=0.003 and p=0.024, respectively). Compared to CONT average sled push times were slower 3 and 24 h following DHY (19±15%; p=0.001; g=1.229 and 14±15%; p=0.012; g=0.671, respectively). When compared to the CONT hand grip was weaker 3 h following DHY (53±8 and 51±8 kg; p=0.044, g=0.243 respectively) and medicine ball chest throw distances were shorter 24 h following DHY (474±52 and 449±44 cm; p=0.016, g=0.253 respectively). No significant differences were observed in vertical jump (p=0.467). Urine specific gravity was higher than CONT 20 min (p=0.035) and 24 h (p=0.035) following DHY. Acute dehydration of 4.8% body mass results in reduced physical performance 3 and 24 h following. There is need for caution when athletes use dehydration for weight loss 24 h prior to competition.

  13. Hybridization between a native and introduced predator of Adelgidae: An unintended result of classical biological control

    Treesearch

    N.P. Havill; Gina Davis; David Mausel; Joanne Klein; Richard McDonald; Cera Jones; Melissa Fischer; Scott Salom; Adelgisa Caccone

    2012-01-01

    Hybridization between introduced biological control agents and native species has the potential to impact native biodiversity and pest control efforts. This study reports progress towards predicting the outcome of hybridization between two beetle species, the introduced Laricobius nigrinus Fender and the native L. rubidus LeConte...

  14. New Staphylinidae (Coleoptera) records with new collection data from New Brunswick, Canada: Paederinae

    PubMed Central

    Webster, Reginald P.; DeMerchant, Ian

    2012-01-01

    Abstract We report 17 species of Paederinae new for New Brunswick, Canada. Ten of these species, Lathrobium othioides LeConte, Lathrobium amplipenne Casey, Lathrobium armatum Say, Lathrobium confusum LeConte, Lathrobium debile LeConte, Achenomorphus corticinus (Gravenhorst), Rugilus rufipes Germar, Homaeotarsus bicolor (Gravenhorst), Homaeotharsus cribratus (LeConte), and Homaeotarsus pallipes (Gravenhorst) are newly recorded for the Maritime provinces. This brings the total number of Paederinae recorded from New Brunswick to 36 species. Additional records are presented for the recently reported Lathrobium simile LeConte and Lathrobium washingtoni Casey. Collection and habitat data are presented for all species. PMID:22577324

  15. Fatty acid patterns of dog erythrocyte membranes after feeding of a fish-oil based DHA-rich supplement with a base diet low in n-3 fatty acids versus a diet containing added n-3 fatty acids.

    PubMed

    Stoeckel, Katja; Nielsen, Leif Højvang; Fuhrmann, Herbert; Bachmann, Lisa

    2011-10-24

    In dogs, increasing the tissue n-3 fatty acid (FA) content is associated with potential benefit in some medical conditions, e.g. atopic dermatitis, cancer or heart disease. Therefore effectively and conveniently increasing tissue n-3 FA levels in dogs is of interest. Incorporation of dietary n-3 FA into cell membranes may be studied by FA analysis of erythrocyte membranes (EM), because of the correlation of its FA composition with the FA composition of other cells. Aim of the study was to determine whether an n-3 FA additive added to a control diet is as effective in increasing EM n-3 FA content as feeding an n-3 FA enriched diet. Furthermore the time course of the incorporation of dietary n-3 FA into canine EM was investigated. Thirty dogs were randomly divided into three dietary groups with ten dogs per group. CONT got a dry dog food diet which did not contain EPA or DHA. FO got a dry dog food diet with a high EPA and DHA content. ADD got the CONT diet combined with an n-3 FA additive rich in DHA and EPA. After a feeding period of 12 weeks the additive was discontinued in ADD and these dogs were fed CONT diet for another four weeks to observe washout effects. Erythrocyte lipids were extracted from venous blood samples and their FA composition was determined by gas chromatography. The Mann-Whitney-U-test was used to detect significant differences between the different groups and time points. After one week the proportions of n-3 FA, DHA and EPA were already significantly increased in ADD and FO, apparently reaching a plateau within eight weeks. In our study DHA and not EPA was preferably incorporated into the EM. After discontinuing the administration of the additive in ADD, the n-3 FA values declined slowly without reaching baseline levels within four weeks. In dogs, an increase of dietary n-3 FA content leads to a rapid inclusion of n-3 FA into EM, regardless of whether the n-3 FA are offered as an enriched diet or as a normal diet supplemented with an n-3 FA additive.

  16. Fatty acid patterns of dog erythrocyte membranes after feeding of a fish-oil based DHA-rich supplement with a base diet low in n-3 fatty acids versus a diet containing added n-3 fatty acids

    PubMed Central

    2011-01-01

    Background In dogs, increasing the tissue n-3 fatty acid (FA) content is associated with potential benefit in some medical conditions, e.g. atopic dermatitis, cancer or heart disease. Therefore effectively and conveniently increasing tissue n-3 FA levels in dogs is of interest. Incorporation of dietary n-3 FA into cell membranes may be studied by FA analysis of erythrocyte membranes (EM), because of the correlation of its FA composition with the FA composition of other cells. Aim of the study was to determine whether an n-3 FA additive added to a control diet is as effective in increasing EM n-3 FA content as feeding an n-3 FA enriched diet. Furthermore the time course of the incorporation of dietary n-3 FA into canine EM was investigated. Methods Thirty dogs were randomly divided into three dietary groups with ten dogs per group. CONT got a dry dog food diet which did not contain EPA or DHA. FO got a dry dog food diet with a high EPA and DHA content. ADD got the CONT diet combined with an n-3 FA additive rich in DHA and EPA. After a feeding period of 12 weeks the additive was discontinued in ADD and these dogs were fed CONT diet for another four weeks to observe washout effects. Erythrocyte lipids were extracted from venous blood samples and their FA composition was determined by gas chromatography. The Mann-Whitney-U-test was used to detect significant differences between the different groups and time points. Results After one week the proportions of n-3 FA, DHA and EPA were already significantly increased in ADD and FO, apparently reaching a plateau within eight weeks. In our study DHA and not EPA was preferably incorporated into the EM. After discontinuing the administration of the additive in ADD, the n-3 FA values declined slowly without reaching baseline levels within four weeks. Conclusions In dogs, an increase of dietary n-3 FA content leads to a rapid inclusion of n-3 FA into EM, regardless of whether the n-3 FA are offered as an enriched diet or as a normal diet supplemented with an n-3 FA additive. PMID:22024384

  17. Acute Moderate Exercise Does Not Further Alter the Autonomic Nervous System Activity in Patients with Sickle Cell Anemia

    PubMed Central

    Waltz, Xavier; Sinnapah, Stéphane; Lemonne, Nathalie; Etienne-Julan, Maryse; Soter, Valérie; Hue, Olivier; Hardy-Dessources, Marie-Dominique; Barthélémy, Jean-Claude; Connes, Philippe

    2014-01-01

    A decreased global autonomic nervous system (ANS) activity and increased sympathetic activation in patients with sickle cell anemia (SCA) seem to worsen the clinical severity and could play a role in the pathophysiology of the disease, notably by triggering vaso-occlusive crises. Because exercise challenges the ANS activity in the general population, we sought to determine whether a short (<15 min) and progressive moderate exercise session conducted until the first ventilatory threshold had an effect on the ANS activity of a group of SCA patients and a group of healthy individuals (CONT group). Temporal and spectral analyses of the nocturnal heart rate variability were performed before and on the 3 nights following the exercise session. Standard deviation of all normal RR intervals (SDNN), total power, low frequencies (LF) and high frequencies powers (HF) were lower but LF/HF was higher in SCA patients than in the CONT group. Moderate exercise did not modify ANS activity in both groups. In addition, no adverse clinical events occurred during the entire protocol. These results imply that this kind of short and moderate exercise is not detrimental for SCA patients. PMID:24740295

  18. Distributed Decision Making Environment.

    DTIC Science & Technology

    1982-12-01

    Findeisen , F. N. Bailey, M. Brdys, K. Malinowski, P. Tatjewoki and A. Wozniak, Control and Coordination in Hierarchical Systems, New York, NY: Wiley...1977. [99] W. Findeisen et al., "On-line hierarchical control for steady-state systems," IEEE Trans. Automat. Conts., vol. AC-23, no. 2, pp. 189-209

  19. Bacteriophage application restores ethanol fermentation characteristics disrupted by Lactobacillus fermentum

    USDA-ARS?s Scientific Manuscript database

    Background: Contamination of corn mash by lactic acid bacteria (LAB) reduces ethanol yields and the overall efficiency of the ethanol fermentation process, and the industry relies heavily on antibiotics for contamination control. There is a need to develop alternative methods for the control of cont...

  20. A proposed contents astronomy for basic education

    NASA Astrophysics Data System (ADS)

    Albrecht, E.; Voelzke, M. R.

    2014-08-01

    A Astronomia é um tema que sempre exerceu fascínio sobre as pessoas de um modo geral. Conhecer e estudar o que há nos “céus”, além de nossos olhos, continua sendo instigador e de grande interesse. Baseado nestas justificativas desenvolveu-se uma pesquisa de Doutorado, na qual, o objetivo principal foi investigar sobre a presença dos conteúdos de Astronomia nas Propostas Curriculares da região Sul do Brasil, a saber, os estados de Paraná, Rio Grande do Sul e Santa Catarina e, posterior comparação com os Parâmetros Curriculares Nacionais (PCN) que trazem propostas de conteúdos para toda a Educação Básica brasileira. Tal investigação pautou-se na abordagem de caráter qualitativo e utilizouse para tal da Análise de Conteúdos (Bardin, 2011), que possibilitou a construção de quatro categorias, nas quais os conteúdos astronômicos foram agrupados: Terra, Sistema Solar, Via Láctea e Universo. Após a leitura, coleta de dados, construção de categorias, observou-se a dicotomia na apresentação destes conteúdos. As propostas curriculares analisadas foram as de Geografia, Ciências e Física dos estados do Paraná (2008), Rio Grande do Sul (2009) e de Santa Catarina (1998), responsáveis pelo trabalho com Astronomia nestes estados. No Ensino Fundamental, a proposta curricular do estado do Paraná apresenta conteúdos ligados à Astronomia desde o sexto ano até o nono ano, como conteúdo do primeiro bimestre, o que também é apresentado na proposta curricular do estado do Rio Grande do Sul, porém, este, não divide os conteúdos por bimestre e nem por ano, mas por ciclos, sexto e sétimo anos como primeiro ciclo e oitavo e nono anos como segundo ciclo, deixando livre para o professor estruturar sua sequência de conteúdos. A proposta curricular de Santa Catarina não apresenta estes conteúdos de maneira explícita, não divide dos conteúdos nem por ano, nem por série, traz uma sequência de conteúdos para serem trabalhados ao longo dos quatro anos, nos quais, aparecem timidamente alguns conteúdos de Astronomia. Para o Ensino Médio, as propostas curriculares do Paraná e de Santa Catarina parecem que se repetem, apresentando apenas o conteúdo Gravitação Universal, na primeira série do Ensino Médio, já a proposta curricular do Rio Grande do Sul, traz uma sequência que é proposta nos PCN (Brasil, 1998; 1999; 2002), na qual aparece o tema em questão, porém, em todos os anos, em todas as propostas, não há um detalhamento do que, de como trabalhar os conteúdos. O detalhamento facilita a prática pedagógica, pois, conteúdos simples como as Estações do Ano, Fases da Lua, sequer são citados nas propostas curriculares pesquisadas. Outro aspecto observado é que os conteúdos de um modo geral não trazem uma sequência e não primam por partir do entorno do aluno, daquilo que ele conhece para estruturar novos conceitos. Tais aspectos dificultam o fazer pedagógico, pois, por ser uma região com características culturais semelhantes, era esperado que as propostas fossem mais próximas, o! que facilitaria em muito, por exemplo, transferências dentro de um mesmo estado ou interestaduais. Pautando-se no que foi observado, na falta de especificidade dos conteúdos, clareza, sequência dos conteúdos e propostas de trabalho é proposto uma sequência de conteúdos de Astronomia, com materiais e recursos, pois, como apontado por Langhi e Nardi (2009), é necessário fornecer além da informação, do conteúdo, o como fazer. Tal proposta não visa estabelecer-se como regra, mas como suporte ao professor para facilitar sua prática pedagógica e tornar o trabalho com Astronomia presente nas escolas brasileiras. Bardin, L. Análise de conteúdo. Tradução Luís Antero Reto, Augusto Pinheiro. São Paulo: Edições 70, 2011. 279 p. Langhi, R; Nardi, R. Ensino da astronomia no Brasil: educação formal, informal, não-formal e divulgação científica. Revista Brasileira de Ensino de Física, v. 31, n. 4, p. 4402-1 a 4402-11, 2009.

  1. Utilization of nitrogen in cows consuming wet distillers grains with solubles in alfalfa and corn silage-based dairy rations.

    PubMed

    Gehman, A M; Kononoff, P J

    2010-07-01

    The objectives of this experiment were to determine the effects of forage type on nutrient digestibility, purine derivative excretion, nitrogen utilization, and milk production in dairy cattle consuming rations containing high levels of wet distillers grains with solubles (WDGS). Primiparous (n=8) and multiparous (n=20) Holstein cows were used in a replicated 4 x 4 Latin square. Animals were fed 1 of 4 treatments during each 21-d period: 1) CONT-CS, 0% WDGS and high corn silage; 2) CONT-AS, 0% WDGS and high alfalfa silage; 3) WDGS-CS, 25% WDGS and high corn silage; and 4) WDGS-AS, 25% WDGS and high alfalfa silage (dry matter basis). Intake and milk data were collected daily and averaged for d 15 to 21 of each period. Dry matter intake was lower for CONT-CS than for CONT-AS, WDGS-CS, and WDGS-AS (22.5, 24.6, 24.6, and 24.8 kg/d, respectively). Digestibility of dry matter, organic matter, neutral detergent fiber, and N were not affected by treatment, averaging 59.6, 62.3, 40.1, and 58.6%, respectively. Excretion of urinary purine derivatives was greatest for WDGS-AS, followed by WDGS-CS, and then CONT-CS and CONT-AS. Thus, by calculation, estimated microbial protein flow was highest for WDGS-AS (2,189.9 g/d) followed by WDGS-CS (1,996.2 g/d), CONT-AS (1,640.0 g/d), and CONT-CS (1,627.0 g/d). Mass of fecal N was not different among treatments (averaging 287.1+/-14.8 g/d), but urinary and manure N were reduced for rations with WDGS compared with those not including WDGS. Observed 4% fat-corrected milk was greatest for WDGS-AS, followed by WDGS-CS, and then CONT-CS and CONT-AS (30.7, 29.7, 28.3, and 27.2 kg/d, respectively). Milk protein yield was greatest for WDGS-AS (1.00 kg/d), followed by WDGS-CS, and then CONT-AS and CONT-CS (0.96, 0.91, 0.86 kg/d, respectively). This research demonstrated that rations can be balanced for dairy cattle to include up to 25% WDGS and result in increased microbial protein synthesis, milk production, and milk protein yield. Copyright (c) 2010 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  2. Development of kairomone based control programs for cocoa pod borer

    USDA-ARS?s Scientific Manuscript database

    The Cocoa Pod Borer moth presents a unique opportunity to develop host volatile attractants for control strategies for the following reasons. First, knowing what volatiles are critical for host finding by females will allow for development of mass trapping and/or attract and kill strategies to cont...

  3. Continuing Treatment with Salvia miltiorrhiza Injection Attenuates Myocardial Fibrosis in Chronic Iron-Overloaded Mice

    PubMed Central

    Zhang, Ying; Wang, Hao; Cui, Lijing; Zhang, Yuanyuan; Liu, Yang; Chu, Xi; Liu, Zhenyi; Zhang, Jianping; Chu, Li

    2015-01-01

    Iron overload cardiomyopathy results from iron accumulation in the myocardium that is closely linked to iron-mediated myocardial fibrosis. Salvia miltiorrhiza (SM, also known as Danshen), a traditional Chinese medicinal herb, has been widely used for hundreds of years to treat cardiovascular diseases. Here, we investigated the effect and potential mechanism of SM on myocardial fibrosis induced by chronic iron overload (CIO) in mice. Kunming male mice (8 weeks old) were randomized to six groups of 10 animals each: control (CONT), CIO, low-dose SM (L-SM), high-dose SM (H-SM), verapamil (VRP) and deferoxamine (DFO) groups. Normal saline was injected in the CONT group. Mice in the other five groups were treated with iron dextran at 50 mg/kg per day intraperitoneally for 7 weeks, and those in the latter four groups also received corresponding daily treatments, including 3 g/kg or 6 g/kg of SM, 100 mg/kg of VRP, or 100 mg/kg of DFO. The iron deposition was estimated histologically using Prussian blue staining. Myocardial fibrosis was determined by Masson’s trichrome staining and hydroxyproline (Hyp) quantitative assay. Superoxide dismutase (SOD) activity, malondialdehyde (MDA) content and protein expression levels of type I collagen (COL I), type I collagen (COL III), transforming growth factor-β1 (TGF-β1) and matrix metalloproteinase-9 (MMP-9) were analyzed to investigate the mechanisms underlying the effects of SM against iron-overloaded fibrosis. Treatment of chronic iron-overloaded mice with SM dose-dependently reduced iron deposition levels, fibrotic area percentage, Hyp content, expression levels of COL I and COL III, as well as upregulated the expression of TGF- β1 and MMP-9 proteins in the heart. Moreover, SM treatment decreased MDA content and increased SOD activity. In conclusion, SM exerted activities against cardiac fibrosis induced by CIO, which may be attributed to its inhibition of iron deposition, as well as collagen metabolism and oxidative stress. PMID:25850001

  4. Gene expression of porcine blastocysts from gilts fed organic or inorganic selenium and pyridoxine.

    PubMed

    Dalto, B D; Tsoi, S; Audet, I; Dyck, M K; Foxcroft, G R; Matte, J J

    2015-01-01

    In this study, we determined how maternal dietary supplementation with pyridoxine combined with different sources of selenium (Se) affected global gene expression of porcine expanded blastocysts (PEB) during pregnancy. Eighteen gilts were randomly assigned to one of the three experimental diets (n=6 per treatment): i) basal diet without supplemental Se or pyridoxine (CONT); ii) CONT+0.3 mg/kg of Na-selenite and 10 mg/kg of HCl-pyridoxine (MSeB610); and iii) CONT+0.3 mg/kg of Se-enriched yeast and 10 mg/kg of HCl-pyridoxine (OSeB610). All gilts were inseminated at their fifth post-pubertal estrus and killed 5 days later for embryo harvesting. A porcine embryo-specific microarray was used to detect differentially gene expression between MSeB610 vs CONT, OSeB610 vs CONT, and OSeB610 vs MSeB610. CONT gilts had lower whole blood Se and erythrocyte pyridoxal-5-P concentrations than supplemented gilts (P<0.05). No treatment effect was observed on blood plasma Se-glutathione peroxidase activity (P=0.57). There were 10, 247, and 96 differentially expressed genes for MSeB610 vs CONT, OSeB610 vs CONT, and OSeB610 vs MSeB610 respectively. No specific biological process was associated with MSeB610 vs CONT. However, for OSeB610 vs CONT, upregulated genes were related with global protein synthesis but not to selenoproteins. The stimulation of some genes related with monooxygenase and thioredoxin families was confirmed by quantitative real-time RT-PCR. In conclusion, OSeB610 affects PEB metabolism more markedly than MSeB610. Neither Se sources with pyridoxine influenced the Se-glutathione peroxidase metabolic pathway in the PEB, but OSeB610 selectively stimulated genes involved with antioxidant defense. © 2015 Society for Reproduction and Fertility.

  5. Effects of Warm-Up and Fatigue on Knee Joint Position Sense and Jump Performance.

    PubMed

    Romero-Franco, N; Jiménez-Reyes, P

    2017-01-01

    The purpose of this study was to evaluate the effects of a warm-up and fatigue protocol on the vertical jump and knee joint position sense of sprinters. Thirty-two sprinters were randomly allocated to either a control group (CONT) or a plyometric group (PLYO) that performed a warm-up, followed by a high-intensity plyometric protocol. Absolute (AAE), relative (RAE), and variable (VAE) angular errors and vertical jump were evaluated before and after the warm-up, as well as after the plyometric protocol and again 5 min later. After the warm-up, athletes improved RAE and jump performance. After the plyometric protocol, scores on the RAE, VAE, and the vertical jump performance worsened compared to the control group and to the values obtained after the warm-up. Five minutes later, RAE and vertical jump continued to be impaired. AAE did not show significant differences. The vertical jump is improved after the warm-up, although it is deteriorated after high-intensity plyometry. Regarding knee proprioception, the lack of impairments in the AAE make unclear the effects of the plyometric exercises on knee proprioception.

  6. Lipopolysaccharide-induced overproduction of nitric oxide and overexpression of iNOS and interleukin-1β proteins in zinc-deficient rats.

    PubMed

    Miyazaki, Takashi; Takenaka, Tsuneo; Inoue, Tsutomu; Sato, Makiko; Miyajima, Yuka; Nodera, Makoto; Hanyu, Mayuko; Ohno, Yoichi; Shibazaki, Satomi; Suzuki, Hiromichi

    2012-03-01

    Zinc deficiency leads to decreased cellular immune responses. The overproduction of nitrogen species derived from inducible nitric oxide synthase (iNOS), its enzyme, and interleukine-1 beta (IL-1β), and inflammatory cytokine have been implicated in immune responses. The goal of this study was to investigate the effects of lipopolysaccharide (LPS)-induced changes in NO metabolites, iNOS, and IL-1β protein expression in the lungs of zinc-deficient rats. Male Sprague-Dawley rats (body weight, 100 g) were divided into two groups and were fed either a zinc-deficient diet (ZnD) or a zinc-containing diet (Cont). After 4 weeks on these diets, rats received a 10-mg/kg dose of LPS injected via the tail vein and were then maintained for an additional 72 h. To determine total NO concentrations in the blood, serum zinc concentration, iNOS protein expression, IL-1β, and iNOS immunohistochemistry, blood and lung samples were obtained at pre-LPS injection, 5, 24, and 72 h after injection. Total NO levels were significantly increased at 5, at 24, and at 72 h after LPS injection compared with pre-LPS injection level in ZnD group; significant changes in total NO levels was elevated at 5 h from at pre-LPS level but not significant changes from basal level at 24 and 72 h in the control group. Based on western blot analyses and immunohistochemistry, clear bands indicating iNOS and IL-1β protein expression and iNOS antibody-stained inflammatory cells were detected at 5 and 24 h in the ZnD group and 5 h in the Cont group, not observed at 24 and 72 h in the control group. These results suggest that zinc deficiency induces overexpression of iNOS and IL-1β proteins from inflammatory cells around the alveolar blood vessels, resulting in overproduction of total NO and persisted inflammatory response in the zinc-deficient rat lung. Taken together, overexpression of LPS-induced iNOS, overproduction of iNOS-derived NO, and overexpression of IL-1β may induce nitrosative and oxidative stresses in the lung, and these stresses may be involved low immunity of zinc deficiency states.

  7. Department of the Navy Justification of Estimates for Fiscal Year 1984 Submitted to Congress January 1983. Operation & Maintenance, Navy. Book 2. Budget Activity 7: Central Supply & Maintenance.

    DTIC Science & Technology

    1983-01-01

    Sidewinder TD Mods 2/1,291 3/1,762 4/5,540 Cost $130 $252 $573 Snarrow TD Mods 5/2,045 2/186 6/564 Cost $556 $110 $419 Shrike TD Mods -/- 4/2,930 3/2,307 Cost...574 $713 Standard Arm TO/Mods 1/87 ?/351 ?/296 Cost $72 $180 $158 Phoenix TD /Mods 4/889 4/554 3/642 Cost $219 $120 $?67 7 29 Activity Group: Air...Launched Weapons Rework (cont’d) III. Performance Criteria and Evaluation FY 1982 FY 1983 FY 1984 (cont’d) Harpoon TD /Mods 6/396 16/2,512 14/1,195

  8. Wildlife and Tamarix

    USDA-ARS?s Scientific Manuscript database

    In this chapter, we present a synthesis of published literature and preliminary reports on the use of Tamarix by wildlife in riparian systems. We discuss how several groups of wildlife; specifically herpetofauna, birds, and mammals utilize or avoid Tamarix and discuss the impacts of methods for cont...

  9. Assessment Report of US-Japan-Europe Collaborative Research on Probe Data International Probe Data Work Group Phase 2.

    DOT National Transportation Integrated Search

    2016-01-01

    The United States Department of Transportation (USDOT), the Road Bureau of Ministry of Land, Infrastructure, Transport, and Tourism (MLIT) of Japan, and the European Unions European Commission Directorate General for Communications Networks, Conte...

  10. Evaluation of the in-field efficacy of oregano essential oil administration on the control of neonatal diarrhea syndrome in calves.

    PubMed

    Katsoulos, Panagiotis D; Karatzia, Maria A; Dovas, Chrysostomos I; Filioussis, George; Papadopoulos, Elias; Kiossis, Evangelos; Arsenopoulos, Konstantinos; Papadopoulos, Theologos; Boscos, Constantin; Karatzias, Harilaos

    2017-12-01

    The objective of this study was to evaluate under field conditions, whether daily administration of oregano essential oil is effective in preventing and/or diminishing the severity of neonatal diarrhea syndrome in calves aged less than 15days. Ninety-one newborn calves from three dairy farms were assigned into two groups; "Eco" group (n=46) calves were drenched with Greek oregano (Origanum vulgare ssp. Hirtum) essential oil (ECODIAR® liquid 5%) at the dose of 12.5mg/kg body weight once per day until the age of 10days. "Conts" group (n=45) calves were left untreated and served as controls. All animals were monitored daily for the incidence of diarrhea until the age of 15days and their fecal score was recorded. Fecal samples were collected on days 3, 6 and 10 for microbiological and parasitological evaluation. Average fecal score throughout the experiment, incidence of diarrhea, duration and severity of diarrhea episodes were significantly lower in Eco group compared to the controls. Daily administration of oregano essential oil in calves for the first 10days of their life effectively diminishes the severity of naturally acquired diarrhea under field conditions and, under certain hygiene practices, possess a preventive effect against neonatal diarrhea syndrome. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Effects of gastrointestinal parasites on parasite burden, rectal temperature, and antibody titer responses to vaccination and infectious bovine rhinotracheitis virus challenge.

    PubMed

    Schutz, J S; Carroll, J A; Gasbarre, L C; Shelton, T A; Nordstrom, S T; Hutcheson, J P; Van Campen, H; Engle, T E

    2012-06-01

    Thirty-three colostrum-deprived Holstein bull calves (initial BW of 131 ± 4 kg) were used to determine the effect of timing of anthelmintic administration relative to vaccination on antibody titer response to vaccine component antigens. When calves were at least 3 mo of age, they were sorted randomly into individual pens and assigned to 1 of 3 treatment groups, treatments consisted of 1) dewormed 2 wk before vaccination (DPV), 2) dewormed at the time of vaccination (DV), or 3) control, vaccinated but not dewormed (CONT). All calves were inoculated with infective larvae of brown stomach worms (Ostertagia ostertagi) and intestinal worms (Cooperia spp.) on d 1, 7, 10, 14, and 18 for a total dose of 235,710 infective larvae per calf. Calves (DPV and DV) were dewormed on d 21 or 35 with a 10% fenbendazole suspension at 5 mg/kg of BW. On d 35, all calves were vaccinated with a modified-live virus respiratory vaccine containing IBRV (infectious bovine rhinotracheitis virus), BVDV-1 (bovine viral diarrhea virus genotype 1), BVDV-2 (BVDV genotype 2), PI-3 (parainfluenza-3), and BRSV (bovine respiratory syncytial virus). During the 103-d experiment, weekly fecal egg counts, blood, and rectal temperatures were collected and health status was recorded daily. Blood samples were obtained weekly to determine serum neutralizing (SN) antibody titers to IBRV, BVDV-1, BVDV-2, and PI-3 and cytokine levels for IL-4, IL-6, TNF-α (tumor necrosis factor-α), and IFN-γ (interferon-gamma). There was a tendency (P < 0.09) for CONT calves to have greater IL-4 concentrations. By design, control calves had greater (P < 0.01) fecal egg counts during the experiment. All calves developed antibody titers to IBRV, BVDV-1, BVDV-2, and PI-3 by d 15 postvaccination. On d 88, all calves were challenged with IBRV and blood samples were obtained on d 88, 89, 90, 93, 95, 98, 99, and 103. All calves had increased rectal temperatures during the final 7 d of the IBRV challenge. However, the CONT group had greater (P < 0.01) rectal temperatures on each sampling day except d 90 compared with the DPV and DV treatments. Therefore, deworming before or at vaccination reduced parasite burden and decreased rectal temperature increase after an IBRV challenge. Deworming strategy had no effect on antibody response to vaccination or IBRV challenge.

  12. Effects of prenatal alcohol exposure in a prospective sample of young adults: Mental health, substance use, and difficulties with the legal system.

    PubMed

    Lynch, Mary Ellen; Kable, Julie A; Coles, Claire D

    2017-11-01

    Few studies have focused on the transition to adulthood in adults with prenatal alcohol exposure (PAE). In this study, we examine the occurrence of problem behavior at this transition, including mental health problems, substance use, and difficulties with the legal system. The sample is prospective and provides an opportunity to examine effects of a wide range of prenatal exposure. Adults with PAE were expected to show more problem behavior; the impact of level of exposure was examined as well. The sample was drawn from a predominantly low-income, African-American population. Mothers of the alcohol-exposed participants (n=123) and those in the non-exposed SES-Control group (CONT) (n=59) were recruited at a prenatal visit when information on alcohol and drug use during pregnancy was collected. A disability contrast group (n=54) was recruited at adolescence. The adults with PAE were assigned to three groups varying in physical and cognitive effects of exposure. This report is based on the adults' responses to interviews or questionnaires on problem behavior and laboratory tests related to substance use. Adults with PAE showed more problem behavior in all three areas than adults from the CONT group. For mental health problems, the exposed group showing cognitive, but not physical effects, had the highest scores; their scores were similar, however, to those of the disability contrast group on several scales. Results for outcomes on substance use and legal difficulties were less consistent, but, when significant effects occurred, the group that was exposed, but neither physically nor cognitively affected, was more likely to show negative outcomes. Males in this group were most involved in these behaviors. Effects of PAE continue into early adulthood and affect mental health problems, substance use, and interactions with the legal system. Adults who are exposed, but less physically affected, seem to be the most involved in problem behavior. More research is necessary to examine environmental effects in conjunction with PAE on these outcomes and to provide a basis for developing potential interventions. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Effects of low-intensity bench press training with restricted arm muscle blood flow on chest muscle hypertrophy: a pilot study.

    PubMed

    Yasuda, Tomohiro; Fujita, Satoshi; Ogasawara, Riki; Sato, Yoshiaki; Abe, Takashi

    2010-09-01

    Single-joint resistance training with blood flow restriction (BFR) results in significant increases in arm or leg muscle size and single-joint strength. However, the effect of multijoint BFR training on both blood flow restricted limb and non-restricted trunk muscles remain poorly understood. To examine the impact of BFR bench press training on hypertrophic response to non-restricted (chest) and restricted (upper-arm) muscles and multi-joint strength, 10 young men were randomly divided into either BFR training (BFR-T) or non-BFR training (CON-T) groups. They performed 30% of one repetition maximal (1-RM) bench press exercise (four sets, total 75 reps) twice daily, 6 days week(-1) for 2 weeks. During the exercise session, subjects in the BFR-T group placed elastic cuffs proximally on both arms, with incremental increases in external compression starting at 100 mmHg and ending at 160 mmHg. Before and after the training, triceps brachii and pectoralis major muscle thickness (MTH), bench press 1-RM and serum anabolic hormones were measured. Two weeks of training led to a significant increase (P<0.05) in 1-RM bench press strength in BFR-T (6%) but not in CON-T (-2%). Triceps and pectoralis major MTH increased 8% and 16% (P<0.01), respectively, in BFR-T, but not in CON-T (-1% and 2%, respectively). There were no changes in baseline concentrations of anabolic hormones in either group. These results suggest that BFR bench press training leads to significant increases in muscle size for upper arm and chest muscles and 1-RM strength.

  14. Direct control of western pine beetle (Dendroctonus brevicomis LeConte): review and assessment

    Treesearch

    Richard H. Smith

    1990-01-01

    Nearly 70 years of research and application are reviewed and assessed. Results of direct control projects can be characterized as generally effective, temporary, quite variable, and unpredictable in reducing subsequent tree mortality. Some causes of this characterization are variable and difficult stand conditions and logistics, lack of good beetle population...

  15. GEOMORPHIC CONTROLS ON MEADOW ECOSYSTEMS – INSIGHTS INTO LOCAL PROCESSES USING NEAR-SURFACE SEISMIC TECHNIQUES AND GROUND PENETRATING RADAR

    EPA Science Inventory

    Geomorphic controls on riparian meadows in the Central Great Basin of Nevada are an important aspect in determining the formation of and planning the management of these systems. The current hypothesis is that both alluvial fan sediment and faulted bedrock steps interact to cont...

  16. Pre-release biological control agent recommendations for swallow-wort (Vincetoxicum spp.) informed by demographic matrix models

    USDA-ARS?s Scientific Manuscript database

    Weed biological control workers have advocated for the advance assessment of agent efficacy in order to minimize the release of host-specific but ineffective agents. One method involves demographic matrix modeling of target weed populations in order to identify plant life stage transitions that cont...

  17. Adipose tissue redistribution caused by an early consumption of a high sucrose diet in a rat model.

    PubMed

    Castellanos Jankiewicz, Ashley Kate; Rodríguez Peredo, Sofía Montserrat; Cardoso Saldaña, Guillermo; Díaz Díaz, Eulises; Tejero Barrera, María Elizabeth; del Bosque Plata, Laura; Carbó Zabala, Roxana

    2015-06-01

    Obesity is a major public health problem worldwide. The quantity and site of accumulation of adipose tissue is of great importance for the physiopathology of this disease. The aim of this study was to assess the effect of a high carbohydrate diet on adipose tissue distribution. Male Wistar rats, control (CONT) and high sucrose diet (HSD; 30% sucrose in their drinking water), were monitored during 24 weeks and total energy and macronutrient intake were estimated by measuring daily average consumption. A bioelectrical impedance procedure was performed at 22 weeks of treatment to assess body compartments and systolic arterial blood pressure was measured. Serum was obtained and retroperitoneal adipose tissue was collected and weighed. HSD ingested less pellets and beverage, consuming less lipids and proteins than CONT, but the same amount of carbohydrates. Retroperitoneal adipose tissue was more abundant in HSD. Both groups were normoglycemic; triglycerides, adiponectin and leptin levels were higher, while total cholesterol and HDL-cholesterol were lower in HSD; insulin, HOMA index and systolic blood pressure had a tendency of being higher in HSD. This model presents dyslipidemia and a strong tendency for insulin resistance and hypertension. Even though there was no difference in body compartments between groups, retroperitoneal adipose tissue was significantly increased in HSD. This suggests that a rearrangement of adipose tissue distribution towards the abdominal cavity takes place as a result of chronic high sucrose consumption, which contributes to a higher risk of suffering from metabolic and chronic degenerative diseases. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  18. Effects of long-term administration of omeprazole on bone mineral density and the mechanical properties of the bone.

    PubMed

    Yanagihara, Gabriela Rezende; de Paiva, Aline Goulart; Neto, Maurílio Pacheco; Torres, Larissa Helena; Shimano, Antônio Carlos; Louzada, Mário Jefferson Quirino; Annoni, Raquel; de Oliveira Penoni, Álvaro César

    2015-01-01

    Epidemiological studies have shown a relationship between long-term use of proton pump inhibitors and bone metabolism. However, this relationship has not yet become established. The aim of the present study was to analyze the mechanical properties and bone mineral density (BMD) of rats that were subjected to long-term omeprazole use. Fifty Wistar rats weighing between 200 and 240 g were divided equally into five groups: OMP300 (omeprazole intake at a dose of 300 μmoL/kg/day); OMP200 (200 μmoL/kg/day); OMP40 (40 μmoL/kg/day); OMP10 (10 μmoL/kg/day); and Cont (control group; intake of dilution vehicle). The solutions were administered for 90 consecutive days. After the rats had been sacrificed, their BMD, the mechanical properties of the dissected femurs and their serum Ca++ levels were analyzed. The BMD of the OMP300 group was lower than that of the controls (p = 0.006). There was no difference on comparing the OMP200, OMP40 and OMP10 groups with the controls. The maximum strength and rigidity of the femur did not differ in the experimental groups in comparison with the controls. The OMP300 group had a statistically lower serum Ca++ concentration than that of the controls (p = 0.049), but the other groups did not show any difference in relation to the controls. Daily intake of 300 μmoL/kg/day of omeprazole decreased the BMD of the femur, but without changes to the rigidity and strength of the femur in adult rats.

  19. EOP and scale from continuous VLBI observing: CONT campaigns to future VGOS networks

    NASA Astrophysics Data System (ADS)

    MacMillan, D. S.

    2017-07-01

    Continuous (CONT) VLBI campaigns have been carried out about every 3 years since 2002. The basic idea of these campaigns is to acquire state-of-the-art VLBI data over a continuous time period of about 2 weeks to demonstrate the highest accuracy of which the current VLBI system is capable. In addition, these campaigns support scientific studies such as investigations of high-resolution Earth rotation, reference frame stability, and daily to sub-daily site motions. The size of the CONT networks and the observing data rate have increased steadily since 1994. Performance of these networks based on reference frame scale precision and polar motion/LOD comparison with global navigation satellite system (GNSS) earth orientation parameters (EOP) has been substantially better than the weekly operational R1 and R4 series. The precisions of CONT EOP and scale have improved by more than a factor of two since 2002. Polar motion precision based on the WRMS difference between VLBI and GNSS for the most recent CONT campaigns is at the 30 μas level, which is comparable to that of GNSS. The CONT campaigns are a natural precursor to the planned future VLBI observing networks, which are expected to observe continuously. We compare the performance of the most recent CONT campaigns in 2011 and 2014 with the expected performance of the future VLBI global observing system network using simulations. These simulations indicate that the expected future precision of scale and EOP will be at least 3 times better than the current CONT precision.

  20. Transport index limits for shipments of radioactive material in passenger-carrying aircraft.

    DOT National Transportation Integrated Search

    1982-06-01

    To limit radiation exposure in passenger-carrying aircraft the Department of Transportation requires operators of such aircraft to exercise special control over packages of radioactive material bearing a "radioactive yellow" label. The degree of cont...

  1. Research in Energetic Compounds.

    DTIC Science & Technology

    1980-03-01

    SECURITY CLASSIFICATION OF THIS PAGE(When Data Entered) ,2 ABSTRACT (cont’d.) chloroperbenzoic acid gave 3-nitrooxetane. Fluoronitromalonate esters were...tetrahydropyranyl ethers. Base hydrolysis of the ester groups followed by acid hydrolysis of the tetrahydropyranyl groups gave 2-fluo- ro-2-nitroethanol...of 3-allyloxyoxetane.3 Treatment of allyl alcohol with 0.25 equivalunt of t-butyl h-pochlorite and a catalytic amount of p-toluenesulfonic acid was

  2. The Present Status of the Field of Digital Computer Based Industrial Control Systems and the Work of the International Purdue Workshop in Helping to Promote this Field

    DTIC Science & Technology

    1978-09-01

    Strategy for a Class of Static Systems", IEEE Trans, on Auto. Cont., AC-17, 7-15 (1972). 14. Findeisen , W., and Lefkowitz, I., "Design and Applications...of Multilayer Control", Proc. Fourth IFAC Congress, Warsaw, 1969. 15. Findeisen , W., Multilevel Control Systems, Panstwowe Wydawnictwo Naukowe

  3. Coping with Pain in the Motivational Context of Values: Comparison between an Acceptance-Based and a Cognitive Control-Based Protocol

    ERIC Educational Resources Information Center

    Paez-Blarrina, Marisa; Luciano, Carmen; Gutierrez-Martinez, Olga; Valdivia, Sonsoles; Rodriguez-Valverde, Miguel; Ortega, Jose

    2008-01-01

    This study compares the effect of an acceptance-based protocol (ACT) and a cognitive control-based (CONT) protocol on three measures of pain coping: tolerance, self-report, and believability. Specific methodological controls were employed to further isolate the role of the value of participating in a pain task, compared to previous investigations…

  4. Utility accommodation policy of the Iowa State Highway Commission.

    DOT National Transportation Integrated Search

    1973-02-01

    This policy covers. initial placement, adjustment, relocation and : replacement of utility facilities in, on., above or below all highway : right of way over which the Iowa State Highway Corninission exe:tcii:les : cont.rol of access. It embodies the...

  5. First establishment of the planthopper Megamelus scutellaris Berg 1883 (Hemiptera: Delphacidae) released for biological control of water hyacinth in California

    USDA-ARS?s Scientific Manuscript database

    Water hyacinth (Eichhornia crassipes (Martius) Solms-Laubach) is a non-native, invasive floating aquatic weed in the Sacramento San Joaquin Delta and associated river watersheds of northern California. Prior efforts to control water hyacinth biologically in this region have not led to sustained cont...

  6. Effect of sub-anesthetic xylazine and ketamine ('ketamine stun') administered to calves immediately prior to castration.

    PubMed

    Coetzee, Johann F; Gehring, Ronette; Tarus-Sang, Jepkoech; Anderson, David E

    2010-11-01

    To describe the pharmacokinetics, cortisol response and behavioral changes associated with administration of sub-anesthetic xylazine and ketamine prior to castration. Prospective, randomized experiment. Twenty-two male beef calves (260-310 kg). Calves were randomly assigned to receive the following treatment immediately prior to surgical or simulated castration; 1) uncastrated, placebo-treated control (CONT) (n=4),2) Castrated, placebo treated control (CAST) (n=6), 3) castrated with intravenous xylazine (X) (0.05 mg kg(-1)) (n=6), and 4) castrated with IV xylazine (X) (0.05 mg kg(-1) ) combined with ketamine (K) (0.1 mg kg(-1)) (n=6). Blood samples collected over 10 hours post-castration were analyzed by LC-MS-MS for drug concentrations and chemiluminescent immunoassay for cortisol determination. Drug concentrations during the first 60 minutes post-castration fit a one-compartment open model with first-order elimination. The harmonic mean elimination half-lives (± pseudo SD) for X, X with K and K were 12.9 ± 1.2, 11.2 ± 3.1 and 10.6 ± 2.8 minutes, respectively. The proportion of the total area under the effect curve (AUEC) for cortisol during this period was significantly lower in the X group (13 ± 3%; p=0.006) and the X+K group (14 ± 2%; p=0.016) compared with the CAST calves (21 ± 2%). However, after 300 minutes the AUEC in the X group was higher than CAST. Significantly more calves demonstrated attitude that was unchanged from pre-manipulation behavior in the CONT (p=0.021) and X+K treated calves (p=0.0051) compared with the CAST calves. Behavioral changes and lower serum cortisol concentrations during the first 60 minutes post-castration were associated with quantifiable xylazine and ketamine concentrations. Low doses of xylazine and ketamine administered immediately prior to castration may offer a safe, efficacious and cost-effective systemically administered alternative or adjunct to local anesthesia. © 2010 The Authors. Veterinary Anaesthesia and Analgesia © 2010 Association of Veterinary Anaesthetists and the American College of Veterinary Anesthesiologists.

  7. Eucommia leaf extract (ELE) prevents OVX-induced osteoporosis and obesity in rats.

    PubMed

    Zhang, Wenping; Fujikawa, Takahiko; Mizuno, Kaito; Ishida, Torao; Ooi, Kazuya; Hirata, Tetsuya; Wada, Atsunori

    2012-01-01

    The cortex of Eucommia ulmoides Oliver is widely used to treat kidney deficiency in traditional Chinese medicine. Its leaves have recently been reported to have anti-obesity properties in metabolic syndrome-like rat models. Due to a sharp decline in estrogen production, obesity, together with osteoporosis, are common problems in postmenopausal women. In this study, we examined the potential effect of Eucommia leaf extract (ELE) in preventing osteoporosis and obesity induced by ovariectomy (OVX). Forty-six female Wistar rats were divided into six groups: Sham-Cont, OVX-Cont, and four OVX groups administered estradiol and different concentrations of ELE 1.25%, ELE 2.5%, and ELE 5%. Treatments were administered after ovariectomy at six weeks of age and continued for 12 weeks. OVX induced a significant decrease in the bone mineral density (BMD) of the lumbar, femora, and tibiae, together with a marked increase in body mass index (BMI). The administration of 5% ELE led to a significant increase in tibial and femoral BMD, as well as significantly increased bone-strength parameters when compared with OVX-Cont rats. According to the suppressed Dpd and increased osteocalcin concentrations in ELE 5% rats, we suggest that varying proportions of bone formation and bone absorption contributed to the enhanced BMD in the femora and tibiae. In addition, significant decreases in body weight, BMI and fat tissue in 5% ELE rats were also observed. These results suggest that ELE may have curative properties for BMD and BMI in OVX rats, and could provide an alternative therapy for the prevention of both postmenopausal osteoporosis and obesity.

  8. Effects of tributylborane-activated adhesive and two silane agents on bonding computer-aided design and manufacturing (CAD/CAM) resin composite.

    PubMed

    Shinohara, Ayano; Taira, Yohsuke; Sawase, Takashi

    2017-10-01

    The present study was conducted to evaluate the effects of an experimental adhesive agent [methyl methacrylate-tributylborane liquid (MT)] and two adhesive agents containing silane on the bonding between a resin composite block of a computer-aided design and manufacturing (CAD/CAM) system and a light-curing resin composite veneering material. The surfaces of CAD/CAM resin composite specimens were ground with silicon-carbide paper, treated with phosphoric acid, and then primed with either one of the two silane agents [Scotchbond Universal Adhesive (SC) and GC Ceramic Primer II (GC)], no adhesive control (Cont), or one of three combinations (MT/SC, MT/GC, and MT/Cont). A light-curing resin composite was veneered on the primed CAD/CAM resin composite surface. The veneered specimens were subjected to thermocycling between 4 and 60 °C for 10,000 cycles, and the shear bond strengths were determined. All data were analyzed using analysis of variance and a post hoc Tukey-Kramer HSD test (α = 0.05, n = 8). MT/SC (38.7 MPa) exhibited the highest mean bond strengths, followed by MT/GC (30.4 MPa), SC (27.9 MPa), and MT/Cont (25.7 MPa), while Cont (12.9 MPa) and GC (12.3 MPa) resulted in the lowest bond strengths. The use of MT in conjunction with a silane agent significantly improved the bond strength. Surface treatment with appropriate adhesive agents was confirmed as a prerequisite for veneering CAD/CAM resin composite restorations.

  9. Guide to metropolitan transportation planning under ISTEA : how the pieces fit together

    DOT National Transportation Integrated Search

    1977-01-01

    An overview of the Maine Facility--a two-lane rural highway test site--is presented, and past experimentation conducted at the facility is summarized. Experiments briefly described include Speed Control in Rural School Zones, Evaluation of Speed Cont...

  10. Attenuation of Cyclosporine-Induced Sperm Impairment and Embryotoxicity by Crataegus monogyna Fruit Aqueous Extract

    PubMed Central

    Zahra, Armand; Gholamreza, Najafi; Farokhi, Farah; Shalizar Jalali, Ali

    2013-01-01

    Objective: Cyclosporine (Cs), a cyclic undecapeptide with potent immuno suppressive activity, causes several adverse effects including reproductive toxicity. This study aims to examine the ability of Crataegus monogyna aqueous fruit extract as an antioxidant to protect against Cs-induced reproductive toxicity. Materials and Methods: In this experimental study, 32 adult male Wistar rats were divided into four groups of eight animals each. Rats in two groups received 40 mg/kg/day Cs for 45 days by oral gavage. In addition, one of the two groups received Crataegus monogyna aqueous extract at a dose of 20 mg/kg/day orally four hours after Cs administration. The remaining two groups consisted of a vehicle treated control (Cont) group and a Crataegus monogyna control (Cr) group. Differences between groups were assessed by analysis of variance (ANOVA) using the SPSS software package for Windows. Results: Cs treatment caused a signiifcant decrease in sperm count and viability with an increase in DNA damage and protamine deifciency of the sperm cells. We observed signiifcant decreases in fertilization rate and embryonic development, in addition to an increased rate of embryo arrest in Cs-treated rats. Crataegus monogyna co-administration attenuated all Cs-induced negative changes in the above-mentioned parameters. Conclusion: Supplementation with Crataegus monogyna a queous fruit extract could be useful against reproductive toxicity during Cs treatment in a rat model PMID:24027659

  11. Short-term effects of chlorpyrifos and other pesticides on earthworm numbers

    USDA-ARS?s Scientific Manuscript database

    Chlorpyrifos is generally used on grasses grown for seed to control billbugs (Sphenophorus venatus confluens) and cutworms (various species), and on other crops for crane fly larvae (Tipula sp.), garden symphyllans (Scutigerella immaculate), and wireworms (Agriotes sp.). The indirect impact of cont...

  12. Western Pine Beetle

    Treesearch

    Clarence J. Jr. DeMars; Bruce H. Roettgering

    1982-01-01

    The western pine beetle, Dendroctonus brevicomis LeConte, can aggressively attack and kill ponderosa and Coulter pine trees of all ages and vigor classes that are 6 inches (15 cm) or larger in diameter, including apparently healthy trees. Group killing of trees is common in dense, overstocked stands of pure, even-aged, young sawtimber (fig. 1), but also occurs among...

  13. Detonation Characteristics of Mixtures of HMX and Emulsion Explosives

    DTIC Science & Technology

    1989-04-01

    and an aqueous emulsion explo- sive have been determined. The emulsion explosive consisted of amonium - nitrate , sodium- nitrate and water in the...1989 D Cb ID A Final Report C14 Approved for public release; distribution unlimited. AIR FORCE WEAPONS LABORATORY Air Force Systems Command Kirtland...TERMS (ContInue on nvwn Nf ocosury and idsŘ by block number) FIELD GROUP SUB-GROUP Explosives; Ammonium Nitrate ;- 19 01Emulsion Explosives; ( 07 04

  14. Energy expenditure and EPOC between water-based high-intensity interval training and moderate-intensity continuous training sessions in healthy women.

    PubMed

    Schaun, Gustavo Zaccaria; Pinto, Stephanie Santana; Praia, Aline Borges de Carvalho; Alberton, Cristine Lima

    2018-02-05

    The present study compared the energy expenditure (EE) during and after two water aerobics protocols, high-intensity interval training (HIIT) and moderate continuous training (CONT). A crossover randomized design was employed comprising 11 healthy young women. HIIT consisted of eight 20s bouts at 130% of the cadence associated with the maximal oxygen consumption (measured in the aquatic environment) with 10s passive rest. CONT corresponded to 30 min at a heart rate equivalent to 90-95% of the second ventilatory threshold. EE was measured during and 30 min before and after the protocols and excess post-exercise oxygen consumption (EPOC) was calculated. Total EE during session was higher in CONT (227.62 ± 31.69 kcal) compared to HIIT (39.91 ± 4.24 kcal), while EE per minute was greater in HIIT (9.98 ± 1.06 kcal) than in CONT (7.58 ± 1.07 kcal). Post-exercise EE (64.48 ± 3.50 vs. 63.65 ± 10.39 kcal) and EPOC (22.53 ± 4.98 vs.22.10 ± 8.00 kcal) were not different between HIIT and CONT, respectively. Additionally, oxygen uptake had already returned to baseline fifteen minutes post-exercise. These suggest that a water aerobics CONT session results in post-exercise EE and EPOC comparable to HIIT despite the latter supramaximal nature. Still, CONT results in higher total EE.

  15. The influence of evaluation protocol on time spent exercising at a high level of oxygen uptake during continuous cycling.

    PubMed

    Merry, K L; Glaister, M; Howatson, G; Van Someren, K

    2015-10-01

    This study evaluated the effects of protocol variation on the time spent exercising at ≥95% V̇O2max during cycle ergometer trials performed at the exercise intensity associated with V̇O2max (iV̇O2max). Nine male triathletes (age: 32±10 years; body mass: 73.3±6.1 kg; stature: 1.79±0.07 m; V̇O2max: 3.58±0.45 L.min(-1)) performed four exercise tests. During tests 1 and 2, participants performed a maximal incremental cycle ergometer test using different stage durations (1 min and 3 min) for the determination of iV̇O2max (1 min) and iV̇O2max (3 min). During tests 3 and 4, participants performed a continuous bout of exhaustive cycling at iV̇O2max (1 min) (CONT1) and iV̇O2max (3 min) (CONT3). iV̇O2max (1 min) was significantly greater (P<0.001) than iV̇O2max (3 min) (340±31 W vs. 299±44 W). Time to exhaustion (TTE) measured during CONT3 was significantly longer (P<0.001) than CONT1 (529±140 s vs. 214±65 s). Time spent at V̇O2max was significantly longer (P=0.036) during CONT3 than CONT1 (146±158 s vs. 11±20 s), and time spent at ≥95% V̇O2max was significantly longer (P=0.005) during CONT3 than CONT1 (326±211 s vs. 57±51 s). These results show that when exercising continuously at iV̇O2max, time spent at ≥95% V̇O2max is influenced by the initial measurement of iV̇O2max.

  16. Reducing production of fumonisin mycotoxins in Fusarium verticillioides by RNA interference

    USDA-ARS?s Scientific Manuscript database

    The fungus Fusarium verticillioides (Fv) is a maize pathogen that can produce fumonisin mycotoxins in ears under certain environmental conditions. Because fumonisins pose health risks to humans and livestock, control strategies with minimal risk to the environment are needed to reduce fumonisin cont...

  17. IMPLEMENTATION OF NATURAL ATTENUATION AT A JP-4 JET FUEL RELEASE AFTER ACTIVE REMEDIATION

    EPA Science Inventory

    After eighteen months of active remediation at a JP-4 jet-fuel spill, a residual of unremediated hydrocarbon remained. Further site characterization was conducted to evaluate the contribution of natural attenuation to control exposure to hazards associated with the residual cont...

  18. Impact of long-term high-intensity interval and moderate-intensity continuous training on subclinical inflammation in overweight/obese adults.

    PubMed

    Gerosa-Neto, José; Antunes, Barbara M M; Campos, Eduardo Z; Rodrigues, Jhennyfer; Ferrari, Gustavo D; Rosa Neto, José C; Bueno, Carlos R; Lira, Fábio S

    2016-12-01

    Obesity is a risk factor able to trigger several inflammatory alterations and the imbalance between pro- and anti-inflammatory cytokine productions. Physical exercise is an important strategy for reduction of inflammatory established process. The aim of this study was to evaluate the effect of 16 weeks of three exercise training programs in the inflammatory profile and insulin resistance in overweight/obesity. Thirty two men and women (46.4±10.1 years; 162.0±9.1 cm; 82.0±13.6 kg) were divided into three groups for training on a treadmill: continuous at 70% maximum heart rate (HRmax) 5 times a week (CONT); 1×4 min (1-bout) and 4×4 min (high intensity interval training, HIIT) at 90% HRmax 3 times a week. Interleukin (IL) 6 and IL-10, tumor necrosis factor-alpha (TNF-α), insulin and adiponectin levels were analyzed by enzyme-linked immunosorbent assay, and homeostasis model assessment insulin resistance was calculated. After 16 weeks of training blood concentrations of IL-6 decreased in the HIIT group ( P =0.035), TNF-α decreased in the CONT ( P =0.037) and increased in HIIT ( P =0.001) and adiponectin decreased in the three training models. There was a trend towards decreased body weight and body mass index (BMI) after HIIT only ( P =0.059 and P =0.060, respectively). Despite the decrease of adiponectin and the increase of TNF-α in HIIT group, insulin sensitivity showed a trend for improvement ( P =0.08). HIIT program decreased IL-6 at rest and although not significant was the only who tended to decrease total body weight and BMI. Taken together, our data suggest that both HIIT as well as CONT exercises training program promotes changes in inflammatory profile in overweight/obesity, but dissimilar response is seen in TNF-α levels.

  19. Verbal learning in the context of background music: no influence of vocals and instrumentals on verbal learning

    PubMed Central

    2014-01-01

    Background Whether listening to background music enhances verbal learning performance is still a matter of dispute. In this study we investigated the influence of vocal and instrumental background music on verbal learning. Methods 226 subjects were randomly assigned to one of five groups (one control group and 4 experimental groups). All participants were exposed to a verbal learning task. One group served as control group while the 4 further groups served as experimental groups. The control group learned without background music while the 4 experimental groups were exposed to vocal or instrumental musical pieces during learning with different subjective intensity and valence. Thus, we employed 4 music listening conditions (vocal music with high intensity: VOC_HIGH, vocal music with low intensity: VOC_LOW, instrumental music with high intensity: INST_HIGH, instrumental music with low intensity: INST_LOW) and one control condition (CONT) during which the subjects learned the word lists. Since it turned out that the high and low intensity groups did not differ in terms of the rated intensity during the main experiment these groups were lumped together. Thus, we worked with 3 groups: one control group and two groups, which were exposed to background music (vocal and instrumental) during verbal learning. As dependent variable, the number of learned words was used. Here we measured immediate recall during five learning sessions (recall 1 – recall 5) and delayed recall for 15 minutes (recall 6) and 14 days (recall 7) after the last learning session. Results Verbal learning improved during the first 5 recall sessions without any strong difference between the control and experimental groups. Also the delayed recalls were similar for the three groups. There was only a trend for attenuated verbal learning for the group passively listened to vocals. This learning attenuation diminished during the following learning sessions. Conclusions The exposure to vocal or instrumental background music during encoding did not influence verbal learning. We suggest that the participants are easily able to cope with this background stimulation by ignoring this information channel in order to focus on the verbal learning task. PMID:24670048

  20. Diet improvement for western corn rootworm (Coleoptera: Chrysomelidae) larvae

    USDA-ARS?s Scientific Manuscript database

    The western corn rootworm (WCR), Diabrotica virgifera virgifera LeConte, is the most serious insect pest of corn (Zea mays L.) in the United States and parts of Europe, and arguably the world’s most expensive pest to control. Several diet formulations are currently used by industry and researchers t...

  1. Integrated Component Fluidic Servovalves and Position Control Systems

    DTIC Science & Technology

    1983-04-01

    35807 ATTN DRSMI- RG , WILLIAM GRIFFITHATTN DRSMI-TGC, J. C. DUNAWAY ATTN DRCPM-TOE, FRED J. CHEPLEN REDSTONE ARSENAL, AL 35898 77 hyJ DISTRIBUT10N (Cont...ARMY TANK AUTOMOTIVE COMMAND ARMOR & COOP DIV, DRDTA-RKT COMMANDER BLDG 215 NAVAL SHIP ENGINEERING CESTER ATTN K. WHITMORE PHILADELPHIA DIVISION WARREN

  2. Establishment of effective control factors to achieve federal enforcement consistency with the Highway Beautification Act : [research summary].

    DOT National Transportation Integrated Search

    2017-10-01

    One of the pleasures of driving in Florida is enjoying a beautiful and diverse landscape. The quality of this view is critical to a states image for visitors and those considering relocation as well as to residents enjoyment. To ensure the cont...

  3. BOOK REVIEW OF "ASSESSMENT AND CONTROL OF NONPOINT SOURCE POLLUTION OF AQUATIC ECOSYSTEMS: A PRACTICAL APPROACH"

    EPA Science Inventory

    This book is geared to environmental specialists and planners, heavy on the technical side. It goes beyond tranditional nonpoint source (NPS) approaches which typically only look at stormwater as athe sole NPS pollution driver. There is some overreaching material beyond the conte...

  4. Nonlinear Control Theory for Missile Autopilot Design.

    DTIC Science & Technology

    1987-04-24

    minimum-time controller which includes constraints on both controls and angle-of-attack is developed and an example is given. -12- - - -~ *% PO PmCF E- A...constructed. In this case, some ideas from robotics on minimum-time trajectory planning under path constraints (see, e.g., Rajan (1985), Sahar and...Auto Cont., Vol. AC-29, No. 4, p. 361. Rajan, V.T. (1985), "Minimum-Time Trajectory Planning ", Proc IEEE Kobotics and Automation Conf., St. Louis. Reed

  5. Tunable Optical Sources.

    DTIC Science & Technology

    1980-11-01

    finite aperture size 5. A. E. Siegman , "Unstable optical resonators for laser of the YAG rod, applications," Proc. IEEE 53, 217-287 (1965); "Unstable...Pumped LiNbO3 Tunable Source Radial Birefringent Element Computer Controlled Laser Attenuator Slab Configuration Laser Source 20. ABSTRACT (Continue on...have invented and demonstrated a computer controlled laser attenu- ator. .... Cont inued DD Il 7 1473 EDITION OF I NOV 01 IS OBSOLETE UNCLASSIFIEDAN

  6. Evaluation of Data Elements for Training Information Feedback System in Context of Post-CGSC Assignments

    DTIC Science & Technology

    1980-08-01

    Appendix B. 12 ------------- ---. _ _ _ _ ______i_____mi__i_ LEGEND Percent of Time Spend Criticalit Aplicability *** on Job Commnent*** t--etc...Communications Officer G-2 Performs communications-electronics (CE) staff functions 6-3 Directs and controls operations of mobile communications...support unit FORM B Cont’d _ _ _ _ -W -l G-4 Establishes and controls mobile area signal center G-5 Manages communications-electronics facilities and

  7. Betacarotene supplementation increases ovulation rate without an increment in LH secretion in cyclic goats.

    PubMed

    Meza-Herrera, Cesar A; Vargas-Beltran, Fermin; Vergara-Hernandez, Hector P; Macias-Cruz, Ulises; Avendaño-Reyes, Leonel; Rodriguez-Martinez, Rafael; Arellano-Rodriguez, Gerardo; Veliz-Deras, Francisco G

    2013-03-01

    This study aimed to evaluate the effects of betacarotene (BC) supplementation on ovulation rate (OR) and luteinizing hormone (LH) secretion in adult goats during the breeding season. Additionally, total ovarian activity (TOA) comprising the total number of ultrasonographically detectable antral follicles (AF) and corpora lutea (OR) was also assessed. In early October, adult goats [n=22, 3.5 years of age, 7/8 Sannen-Alpine; 26°N, 103°W at 1117m.a.s.l.] were randomly assigned to: (i) BC group (BCG), orally supplemented with 50mg of BC/goat/day [n=10; live weight (LW)=45.9±2.0kg, body condition score (BCS; range: 0-emaciated to 5-obese)=3.0±0.1], and (ii) control group (CONT) [n=12; LW=46.2±2.0kg, BCS=3.0±0.1]. All animals received a basal diet of alfalfa hay, corn silage and corn grain, with free access to water and mineral salts. The whole experimental period spanned 34 days before and 17 days after ovulation. On day 23 of the experiment, estrus was synchronized with progestin-releasing intravaginal sponges; 36h prior to estrus, an intensive blood sampling (every 15min for 6h) was performed to determine mean LH concentrations, pulsatility (LH-PULSE) and area under the curve (LH-AUC) for serial LH concentrations. Afterwards, by the end of the luteal phase (i.e., 17 days after the onset of estrus), an ultrasonographic scanning was performed to evaluate OR and TOA [AF+OR]. The average LW and BCS did not differ (p>0.05) during the experimental period. BC-supplemented goats showed an increase in OR (3.4±0.2 versus 2.8±0.2; p<0.05) and exhibited lower (p<0.05) serum LH concentrations, LH-AUC and LH-PULSE compared to CONT. A positive correlation was recorded between OR and LW (r(2)=0.42, p<0.05) and BCS (r(2)=0.47, p<0.05). In addition, AF (5.0±0.6 versus 3.4±0.6) and TOA (8.4±0.6 versus 6.2±0.6) were greater (p<0.05) in the BC-supplemented group than CONT. Supplementation with BC enhanced ovarian follicular development and ovulation rate in adult female goats under decreased photoperiods through LHRH-independant pathways or direct effects of BC on ovarian function. Copyright © 2013 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

  8. Developmental Programming: Reproductive Endocrinopathies in the Adult Female Sheep After Prenatal Testosterone Treatment Are Reflected in Altered Ontogeny of GnRH Afferents

    PubMed Central

    Hershey, John; Mytinger, Andrea; Foster, Douglas L.; Padmanabhan, Vasantha

    2011-01-01

    The GnRH system represents a useful model of long-term neural plasticity. An unexplored facet of this plasticity relates to the ontogeny of GnRH neural afferents during critical periods when the hypothalamic-pituitary-gonadal axis is highly susceptible to perturbation by sex steroids. Sheep treated with testosterone (T) in utero exhibit profound reproductive neuroendocrine dysfunctions during their lifespan. The current study tested the hypothesis that these changes are associated with alterations in the normal ontogeny of GnRH afferents and glial associations. Adult pregnant sheep (n = 50) were treated with vehicle [control (CONT)] or T daily from gestational day (GD)30 to GD90. CONT and T fetuses (n = 4–6/treatment per age group) were removed by cesarean section on GD90 and GD140 and the brains frozen at −80°C. Brains were also collected from CONT and T females at 20–23 wk (prepubertal), 10 months (normal onset of puberty and oligo-anovulation), and 21 months (oligo-anovulation in T females). Tissue was analyzed for GnRH immunoreactivity (ir), total GnRH afferents (Synapsin-I ir), glutamate [vesicular glutamate transporter-2 (VGLUT2)-ir], and γ-aminobutyric acid [GABA, vesicular GABA transporter (VGAT)-ir] afferents and glial associations (glial fibrillary acidic protein-ir) with GnRH neurons using optical sectioning techniques. The results revealed that: 1) GnRH soma size was slightly reduced by T, 2) the total (Synapsin-I) GnRH afferents onto both somas and dendrites increased significantly with age and was reduced by T, 3) numbers of both VGAT and VGLUT inputs increased significantly with age and were also reduced by T, and 4) glial associations with GnRH neurons were reduced (<10%) by T. Together, these findings reveal a previously unknown developmental plasticity in the GnRH system of the sheep. The altered developmental trajectory of GnRH afferents after T reinforces the notion that prenatal programming plays an important role in the normal development of the reproductive neuroendocrine axis. PMID:21933866

  9. Construction and validation of the Self-care Assessment Instrument for patients with type 2 diabetes mellitus.

    PubMed

    Mendonça, Simonize Cunha Barreto de; Zanetti, Maria Lúcia; Sawada, Namie Okino; Barreto, Ikaro Daniel de Carvalho; Andrade, Joseilze Santos de; Otero, Liudmila Miyar

    2017-06-05

    to construct and validate the contents of the Self-care Assessment instrument for patients with type 2 diabetes mellitus. methodological study, based on Orem's General Theory of Nursing. The empirical categories and the items of the instrument were elucidated through a focus group. The content validation process was performed by seven specialists and the semantic analysis by 14 patients. The Content Validity Indices of the items, ≥0.78, and of the scale, ≥0.90, were considered excellent. the instrument contains 131 items in six dimensions corresponding to the health deviation self-care requisites. Regarding the maintenance, a Content Validity Index of 0.98 was obtained for the full set of items, and, regarding the relevance, Content Validity Indices ≥0.80 were obtained for the majority of the assessed psychometric criteria. the instrument showed evidence of content validity. construir e validar o conteúdo do instrumento Avaliação do Autocuidado para pacientes com diabetes mellitus tipo 2. estudo metodológico, fundamentado na Teoria Geral de Enfermagem de Orem. As categorias empíricas e os itens do instrumento foram elucidados por meio de grupo focal. O processo de validação de conteúdo foi realizado por sete especialistas e a análise semântica por 14 pacientes. Foram considerados como excelente Índice de Validade de Conteúdo dos itens ≥ 0,78 e da escala ≥ 0,90. o instrumento contém seis dimensões correspondentes aos requisitos de autocuidado para o desvio da saúde, desmembradas em 131 itens. Quanto à permanência, obteve-se para o conjunto total de itens Índice de Validade de Conteúdo de 0,98, e quanto à adequação Índice de Validade de Conteúdo ≥ 0,80 para maioria dos critérios psicométricos avaliados. o instrumento mostrou evidências de validade de conteúdo. construir y validar el contenido del instrumento Evaluación del Autocuidado para pacientes con diabetes mellitus tipo 2. estudio metodológico, fundamentado en la Teoría General de Enfermería de Orem. Las categorías empíricas y los ítems del instrumento fueron elucidados por medio de grupo focal. El proceso de validación de contenido fue realizado por siete especialistas y el análisis semántico por 14 pacientes. Fueron considerados como excelente el Índice de Validez de Contenido de los ítems ≥ 0,78 y la escala ≥ 0,90. el instrumento contiene seis dimensiones correspondientes a los requisitos de autocuidado para los agravios a la salud, desmembradas en 131 ítems. En cuanto a la permanencia, se obtuvo 0,98, para el conjunto total de ítems del Índice de Validez de Contenido y en la adecuación del Índice de Validez de Contenido ≥ 0,80, para la mayoría de los criterios psicométricos evaluados. el instrumento mostró evidencias de validez de contenido.

  10. Spatiotemporal Dynamics of Speech Sound Perception in Chronic Developmental Stuttering

    ERIC Educational Resources Information Center

    Liotti, Mario; Ingham, Janis C.; Takai, Osamu; Paskos, Delia Kothmann; Perez, Ricardo; Ingham, Roger J.

    2010-01-01

    High-density ERPs were recorded in eight adults with persistent developmental stuttering (PERS) and eight matched normally fluent (CONT) control volunteers while participants either repeatedly uttered the vowel "ah" or listened to their own previously recorded vocalizations. The fronto-central N1 auditory wave was reduced in response to spoken…

  11. Laboratory Investigation of Rill Erosion on Compost Blankets under Concentrated Flow Conditions

    EPA Science Inventory

    A flume study was conducted using a soil, yard waste compost, and an erosion control compost to investigate the response to concentrated flow and determine if the shear stress model could be used to describe the response. Yard waste compost (YWC) and the bare Cecil soil (CS) cont...

  12. The effect of western corn rootworm (Coleoptera: Chrysomelidae) and water deficit on maize performance under controlled conditions

    USDA-ARS?s Scientific Manuscript database

    A series of greenhouse experiments using three infestation levels of the western corn rootworm, Diabrotica virgifera virgifera LeConte, under well-watered, moderately dry, and very dry soil moisture levels were conducted to quantify the interaction of western corn rootworm and soil water deficit on ...

  13. VLBI and GPS-based Time-Transfer Using CONT08 Data

    NASA Technical Reports Server (NTRS)

    Rieck, Carsten; Haas, Ruediger; Jaldehag, Kenneth; Jahansson, Jan

    2010-01-01

    One important prerequisite for geodetic Very Long Baseline Interferometry (VLBI) is the use of frequency standards with excellent short term stability. This makes VLBI stations, which are often co-located with Global Navigation Satellite System (GNSS) receiving stations, interesting for studies of time- and frequency-transfer techniques. We present an assessment of VLBI time-transfer based on the data of the two week long consecutive IVS CONT08 VLBI campaign by using GPS Carrier Phase (GPSCP). CONT08 was a 15 day long campaign in August 2008 that involved eleven VLBI stations on five continents. For CONT08 we estimated the worst case VLBI frequency link stability between the stations of Onsala and Wettzell to 1e-15 at one day. Comparisons with GPSCP confirm the VLBI results. We also identify time-transfer related challenges of the VLBI technique as used today.

  14. CONT14: Preparation and Prospects

    NASA Astrophysics Data System (ADS)

    Behrend, Dirk; Thomas, Cynthia; Himwich, Ed; MacMillan, Dan

    2014-12-01

    In May 2014, a network of seventeen stations at sixteen sites will observe the next continuous VLBI campaign named CONT14. From May 6 through May 20, ten northern hemisphere and seven southern hemisphere stations will record S/X VLBI data for fifteen continuous UT days at a rate of 512 Mbps. This campaign is the continuation of similar campaigns loosely organized every three years. We discuss the preparation work such as allocation of station, media, and correlator resources and the observational procedure that will ensure that the best possible S/X VLBI data set be recorded. With a network size of seventeen stations, CONT14 is a precursor of continuous VGOS-type observing but with the S/X system. In the next several years, continuous VGOS observing on the broadband system will become a reality. With this in mind, we provide an outlook on future prospects of CONT campaigns.

  15. Dietary Alpha-Lipoic Acid Alters Piglet Neurodevelopment.

    PubMed

    Mudd, Austin T; Waworuntu, Rosaline V; Berg, Brian M; Dilger, Ryan N

    2016-01-01

    Alpha-lipoic acid (a-LA) is an antioxidant shown to ameliorate age-associated impairments of brain and cardiovascular function. Human milk is known to have high antioxidant capacity; however, the role of antioxidants in the developing brain is largely uncharacterized. This exploratory study aimed to examine the dose-response effects of a-LA on piglet growth and neurodevelopment. Beginning at 2 days of age, 31 male pigs received 1 of 3 diets: control (CONT) (0 mg a-LA/100 g), low a-LA (LOW) (120 mg a-LA/100 g), or high a-LA (HIGH) (240 mg a-LA/100 g). From 14 to 28 days of age, pigs were subjected to spatial T-maze assessment, and macrostructural and microstructural neuroimaging procedures were performed at 31 days of age. No differences due to diet were observed for bodyweight gain or intestinal weight and length. Spatial T-maze assessment did not reveal learning differences due to diet in proportion of correct choices or latency to choice measures. Diffusion tensor imaging revealed decreased (P = 0.01) fractional anisotropy (FA) in the internal capsule of HIGH-fed pigs compared with both the CONT (P < 0.01)- and LOW (P = 0.03)-fed pigs, which were not different from one another. Analysis of axial diffusivity (AD) within the internal capsule revealed a main effect of diet (P < 0.01) in which HIGH-fed piglets exhibited smaller (P < 0.01) rates of diffusion compared with CONT piglets, but HIGH-fed piglets were not different (P = 0.12) than LOW-fed piglets. Tract-based spatial statistics, a comparison of FA values along white matter tracts, revealed 1,650 voxels where CONT piglets exhibited higher (P < 0.05) values compared with HIGH-fed piglets. The lack of differences in intestinal and bodyweight measures among piglets indicate a-LA supplementation does not impact overall growth, regardless of concentration. Additionally, no observed differences between CONT- and LOW-fed piglets in behavior and neuroimaging measures indicate a low concentration of a-LA does not affect normal brain development. Supplementation of a-LA at a high concentration appeared to alter white matter maturation in the internal capsule, which may indicate delayed neurodevelopment in these piglets.

  16. Mating success, longevity, and fertility of Diabrotica virgifera virgifera LeConte (Chrysomelidae: Coleoptera) in relation to body size and Cry3Bb1 resistant and susceptible genotypes

    USDA-ARS?s Scientific Manuscript database

    Insect resistance to population control methodologies is a widespread problem, with the development of effective resistance management programs often dependent on detailed knowledge regarding the biology of individual species and changes in that biology associated with resistance evolution. This stu...

  17. Natural enemies of adelgids in North America: Their prospect for biological control of Adelges tsugae (Homoptera: Adelgidae)

    Treesearch

    Michael E. Montgomery; Suzanne M. Lyon

    1995-01-01

    On eastern hemlock, we found two resident beetles preying on Adelges tsugae Annand. One is a coccinellid native to Europe, Scymnus suturalis Thunberg, that also feeds on Pineus sp. that attack pines. The other is a native derodontid beetle, Laricobius rubidus LeConte. The seasonal life history...

  18. Transcriptome changes in apple peel tissues during CO2 injury symptom development under controlled atmosphere storage regimens

    USDA-ARS?s Scientific Manuscript database

    Apple (Malus × domestica Borkh.) is one of the most widely cultivated tree crops, and fruit storability is vital to the profitability of the apple fruit industry. Fruit of many apple cultivars can be stored for an extended period due to the introduction of advanced storage technologies such as cont...

  19. Response of maize hybrids with and without rootworm-and drought-tolerance to rootworm infestation under well-watered and drought conditions

    USDA-ARS?s Scientific Manuscript database

    Anecdotal data have suggested that the effect of the western corn rootworm, Diabrotica virgifera virgifera LeConte, is greater under drought and the effect of drought is greater under rootworm infestations, but few experiments have controlled both moisture and rootworm levels. Field studies were con...

  20. The arbuscular mycorrhizal fungus, Glomus irregulare, controls the mycotoxin production of Fusarium sambucinum in the pathogenesis of potato

    USDA-ARS?s Scientific Manuscript database

    Trichothecenes are an important family of mycotoxins produced by several species of the genus Fusarium. These fungi cause serious disease on infected plants and postharvest storage of crops and the toxins can cause health problems for humans and animals. Unfortunately, there are few methods for cont...

  1. Effects of dietary carbohydrates on rumen epithelial metabolism of nonlactating heifers.

    PubMed

    Argov-Argaman, N; Eshel, O; Moallem, U; Lehrer, H; Uni, Z; Arieli, A

    2012-07-01

    Ruminal wall metabolism was studied in nonlactating heifers by altering the carbohydrate (CHO) digestion site between rumen and intestine. The CHO digestion site was estimated from in situ and total-tract digestibility of control (CONT) diets and diets supplemented with corn (CRN), barley (BARL), or soy hulls (SOYH). Ruminal epithelial metabolism regulating gene expression, morphology, and nutrient delivery was assessed from a combination of rumen volatile fatty acid (VFA) concentration, biopsies for papilla morphology, and expression of putative metabolic regulatory genes encoding enzymes that facilitate VFA utilization. Digestible dry matter and CHO intake were 25 and 45% higher, respectively, in the supplemented diets than in CONT diets. Fiber supplementation increased the intestinal and decreased ruminal CHO digestion. Ruminal nonfiber CHO digestibility was 10% lower in CRN than with the high rumen-degradable supplement. The CONT heifers had lowest total ruminal VFA and highest acetate concentration relative to the other treatments. Total VFA concentration in BARL and CRN diets tended to be higher than in SOYH. The SOYH diet tended to reduce papilla dimension relative to CRN and BARL. The CRN diet tended to increase papilla surface area relative to BARL and SOYH. Gene expression of propionyl-coenzyme A carboxylase was higher in CRN and BARL than in SOYH diets, and tended to be higher in CRN than in BARL and SOYH diets. Lactate dehydrogenase and butyryl coenzyme A synthase gene transcripts tended to be higher in CONT than in the supplemented treatments. Thus, rumen epithelial expression of genes involved in VFA metabolism and ruminal wall-structure development are influenced by other regulatory mechanism that is not directly affected by local signals. The in situ methods used are a useful tool for differentiating ruminal from extraruminal nutrient supply. Copyright © 2012 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  2. New state distribution and host records of North American Buprestidae (Coleoptera)

    Treesearch

    Jason A. Hansen; Toby R. Petrice; Robert A. Haack

    2011-01-01

    The following new state records are reported for buprestid species in the eastern United States: Agrilus egeniformis Champlain and Knull and Polyceta elata LeConte from Georgia, Agrilus defectus LeConte and Agrilus vittaticollis (Randall) from Minnesota and Agrilus...

  3. Heavy Lift Helicopter Flight Control System. Volume III. Automatic Flight Control System Development and Feasibility Demonstration

    DTIC Science & Technology

    1977-09-01

    vdI1 SCCLRITY CLASSIFICATIOlN OF THIS PAGE(When DMae ffnifod) Block 20 (Cont): ------ AFCS control laws are examined. Associated documents are: Volume I...both the HII gain and LO gain outputs. Both were traced to defective components. In the former, the HII gain output amplifier AR4 was replaced and in...the latter, a relay in the relay module was defective . 613 S. . ......-. . . 6.2.2.4 ExcessivC Time Lag During the BARO altitude hold evaluation, the

  4. Chemosterilants to control bark beetles...tepa shows promise in preliminary test

    Treesearch

    Robert L. Lyon; Patrick J. Shea

    1967-01-01

    In a preliminary study, two chemosterilants-tepa and hempa-were tested for their effects on the fertility of adult bark beetles (Ips confusus [LeConte). Hempa was Ineffective. Tepa proved 97 percent effective in reducing egg hatch, when applied at 10 µg./10 mg. body weight to both parents. The possibility of using a chemosterilant and the...

  5. Evidence of field-evolved resistance to bifenthrin in western corn rootworm (Diabrotica virgifera virgifera LeConte) populations in western Nebraska and Kansas

    USDA-ARS?s Scientific Manuscript database

    Pyrethroid insecticides are widely used to control larvae or adult western corn rootworm, a key pest of corn in the United States. In response to reports of reduced efficacy of pyrethroids in WCR management programs in southwestern areas of Nebraska and Kansas the present research was designed to es...

  6. Brood production by Xylosandrus germanus (Coleoptera: Curculionidae) and growth of its fungal symbiont on artificial diet based on sawdust of different species

    USDA-ARS?s Scientific Manuscript database

    The ambrosia beetle Xylosandrus germanus (Blanford) (Coleoptera: Curculionidae) is among the most important exotic pests of orchards and nurseries in the US. It attacks a wide range of hosts and is difficult to control using conventional insecticides. As part of our studies on the biology and cont...

  7. Development and characterization of MIR604 resistance in a western corn rootworm population (Coleoptera: Chrysomelidae)

    USDA-ARS?s Scientific Manuscript database

    mCry3A is one of only four proteins licensed for commercial use in Diabrotica control. Utilizing a colony of western corn rootworm, Diabrotica virgifera virgifera LeConte, selected for resistance to mCry3A, we evaluated how mCry3A resistance was inherited and whether fitness costs were associated wi...

  8. War-Fighting in the Early 21st Century: A Remote-Controlled, Robotic, Robust, Size-Reduced, Virtual-Reality Paradigm

    DTIC Science & Technology

    2006-11-27

    clever, but I see that there was nothing in it, after all” – said to Sherlock Holmes – “I begin to think that I make a mistake in explaining... Sherlock Holmes 94 The Criticism from software cont. • Software complexity and performance is improving – Especially in the key area of pattern

  9. 2008 Munitions Executive Summit

    DTIC Science & Technology

    2008-02-21

    7:00pm Hosted Reception 2008 Munitions Executive Summit February 20, 2008 – AGENDA (cont.) 8:00am Administrative Remarks 8:05am PEO Keynote Address...MES Awards Tuesday, February 19 5pm Reception /Pre-registration Sponsored by ATK Ammunition Systems Group and Kaman Aerospace’s Fuzing...15pm Adjourn 5:15pm - 7pm Hosted Reception Sponsored by DSE, Inc. and General Dynamics-OTS Munitions executive suMMit 2008 agenda & prograM

  10. Effect of bioglass on artificially induced enamel lesion around orthodontic brackets: OCT study

    NASA Astrophysics Data System (ADS)

    Bakhsh, Turki; Al-batati, Mohammed; Mukhtar, Mona; Al-Najjar, Mohammed; Bakhsh, Saud; Bakhsh, Abdulsalam; Bakry, Ahmad; Mandurah, Mona; Abbassy, Mona

    2018-02-01

    Background and Objective: White spot lesions (WSLs) are commonly seen after completing orthodontic treatment. Different approaches have been suggested to avoid such a complication. Recently, 45S5 bioglass (BG) was introduced as remineralizing agent. Therefore, the objective of this in-vitro study was to assess the effect of BG in remineralizing WSLs using Optical coherence tomography (OCT). Methods: Fifteen human premolar teeth were sectioned and bonded to orthodontic brackets with Transbond XT primer followed by Transbond PLUS color change adhesive (3M Unitek, USA) on their smooth surfaces according to the manufacturer's instructions. Then, all specimens were varnished excluding the area of interest (AOI) around the bonded restoration, immersed in demineralizing solution and imaged by cross-polarization OCT (CONT group), and the maximum pixel value (MPV) of the AOI were calculated. Then, they were subjected to remineralizing solutions and BG application followed by OCT imaging (REM group). Results: Mann-Whitney test showed the MPV of the AOI in REM was greatly increased and was significantly different from CONT (p<0.05). Conclusion: CP-OCT is a useful diagnostic tool that can be used to detect surface changes in enamel by MPV technique. The BG has a great potential to remineralize enamel defects, however further investigation is required.

  11. Folly Beach, South Carolina. Survey Report on Beach Erosion Control and Hurricane Protection.

    DTIC Science & Technology

    1980-03-28

    ADAlI1 709 CORPS OF ENGINEERS CHARLESTON SC CHARLESTON DISTRICT F/G 13/2 MAR DFOLLY BEACH, SOUTH CAROLINA SURVEY REPORT ON BEACH EROSION CONT--ETCU...Army Corps of Engineers Charleston District P.O. Box 919, Charleston, S.C. 29402 _____________ S. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM...ELEMENT. PROJECT, TASK AREA & WORK UNIT NUMBERS U.S. Army Corps of Engineers Charleston District P.O. Box 919, Charleston, S.C. 29402 1t. CONTROLLING

  12. An Appraisal of a Number of Power Assessment Procedures being Proposed for Use in Chinook-Lycoming T55 Engine

    DTIC Science & Technology

    1989-02-01

    WHICH WILL NOT BE ADDED TO THE DISTIS DATA UNLESS SPECIFICA.LLY REQUESTED. 16. ABSTRACT (CONT.) control ( FADEC ) to the T55-Lll engine. This latter...the Power Assurance Test (PAT) proposed in conjunction with the retrofitting of a full authority digital engine control ( FADEC ) to the T55-Lll engine...Research Laboratory, P.Q. Bcx 4331, felbourne, Victoria, 3001, A..sLralia CONTENTS Page NOMENCLATURE 1.0 INTRODUCTION ........................ 1 2.0 FADEC

  13. Multi-technique comparison of troposphere zenith delays and gradients during CONT08

    NASA Astrophysics Data System (ADS)

    Teke, Kamil; Böhm, Johannes; Nilsson, Tobias; Schuh, Harald; Steigenberger, Peter; Dach, Rolf; Heinkelmann, Robert; Willis, Pascal; Haas, Rüdiger; García-Espada, Susana; Hobiger, Thomas; Ichikawa, Ryuichi; Shimizu, Shingo

    2011-07-01

    CONT08 was a 15 days campaign of continuous Very Long Baseline Interferometry (VLBI) sessions during the second half of August 2008 carried out by the International VLBI Service for Geodesy and Astrometry (IVS). In this study, VLBI estimates of troposphere zenith total delays (ZTD) and gradients during CONT08 were compared with those derived from observations with the Global Positioning System (GPS), Doppler Orbitography and Radiopositioning Integrated by Satellite (DORIS), and water vapor radiometers (WVR) co-located with the VLBI radio telescopes. Similar geophysical models were used for the analysis of the space geodetic data, whereas the parameterization for the least-squares adjustment of the space geodetic techniques was optimized for each technique. In addition to space geodetic techniques and WVR, ZTD and gradients from numerical weather models (NWM) were used from the European Centre for Medium-Range Weather Forecasts (ECMWF) (all sites), the Japan Meteorological Agency (JMA) and Cloud Resolving Storm Simulator (CReSS) (Tsukuba), and the High Resolution Limited Area Model (HIRLAM) (European sites). Biases, standard deviations, and correlation coefficients were computed between the troposphere estimates of the various techniques for all eleven CONT08 co-located sites. ZTD from space geodetic techniques generally agree at the sub-centimetre level during CONT08, and—as expected—the best agreement is found for intra-technique comparisons: between the Vienna VLBI Software and the combined IVS solutions as well as between the Center for Orbit Determination (CODE) solution and an IGS PPP time series; both intra-technique comparisons are with standard deviations of about 3-6 mm. The best inter space geodetic technique agreement of ZTD during CONT08 is found between the combined IVS and the IGS solutions with a mean standard deviation of about 6 mm over all sites, whereas the agreement with numerical weather models is between 6 and 20 mm. The standard deviations are generally larger at low latitude sites because of higher humidity, and the latter is also the reason why the standard deviations are larger at northern hemisphere stations during CONT08 in comparison to CONT02 which was observed in October 2002. The assessment of the troposphere gradients from the different techniques is not as clear because of different time intervals, different estimation properties, or different observables. However, the best inter-technique agreement is found between the IVS combined gradients and the GPS solutions with standard deviations between 0.2 and 0.7 mm.

  14. No Effect of a Whey Growth Factor Extract during Resistance Training on Strength, Body Composition, or Hypertrophic Gene Expression in Resistance-Trained Young Men.

    PubMed

    Dale, Michael J; Coates, Alison M; Howe, Peter R C; Tomkinson, Grant R; Haren, Matthew T; Brown, Andrew; Caldow, Marissa; Cameron-Smith, David; Buckley, Jonathan D

    2017-06-01

    Growth factors can be isolated from bovine milk to form a whey growth factor extract (WGFE). This study examined whether WGFE promoted activation of the AKT/mTOR pathway enabling increased lean tissue mass and strength in resistance trained men. Forty six men with >6 months of resistance training (RT) experience performed 12 weeks of RT. Participants consumed 20 g/day of whey protein and were randomised to receive either 1.6 g WGFE/day (WGFE; n = 22) or 1.6 g cellulose/day (control, CONT; n = 24). The primary outcome was leg press one-repetition maximum (LP1-RM) which was assessed at baseline, 6 and 12 weeks. At baseline and 12 weeks body composition was assessed by dual energy x-ray absorptiometry, and muscle protein synthesis and gene expression were assessed (vastus lateralis biopsy) in a sub-sample (WGFE n = 10, CONT n = 10) pre- and 3 hr post-training. RT increased LP1-RM (+34.9%) and lean tissue mass (+2.3%; p < 0.05) with no difference between treatments (p > 0.48, treatment x time). Post-exercise P70 s6k phosphorylation increased acutely, FOXO3a phosphorylation was unaltered. There were no differences in kinase signalling or gene expression between treatments. Compared with CONT, WGFE did not result in greater increases in lean tissue mass or strength in experienced resistance trained men.

  15. Effects of supplementing zinc or chromium to finishing steers fed ractopamine hydrochloride on growth performance, carcass characteristics, and meat quality.

    PubMed

    Edenburn, B M; Kneeskern, S G; Bohrer, B M; Rounds, W; Boler, D D; Dilger, A C; Felix, T L

    2016-02-01

    Objectives were to determine the effects of feeding ractopamine hydrochloride (RAC) with zinc (Zn) and chromium (Cr) on feedlot growth performance, carcass characteristics, and meat quality. Steers ( = 179; initial BW = 533 ± 94 kg) were blocked by BW and allotted to 30 pens, and pens were randomly assigned 1 of 5 treatments: (1) control (CONT), (2) RAC only (RO), (3) RAC + Zn (RZ), (4) RAC + Cr (RC), or (5) RAC + Zn + Cr (RZC). Trace minerals were fed from d 0 to 63 to target 1 g of Zn/steer·d (KemTRACE Zn; Kemin Industries, Inc., Des Moines, IA) and 3 mg Cr/steer·d (KemTRACE Chromium; Kemin Industries, Inc.) for Zn and Cr treatments, respectively. Dry-rolled corn, 0.605 kg/steer, was removed from the diet and 400 mg RAC, per 0.605 kg of ground corn carrier, was top dressed per steer immediately following feed delivery to pens fed RAC. There were no effects ( ≥ 0.45) of trace mineral supplementation on DMI, ADG, or G:F before RAC feeding. There were also no treatment effects ( ≥ 0.46) over all 63 d of the trial on DMI, ADG, or G:F. Despite the lack of differences in live performance, steers fed RO and RC averaged 0.10 kg/d greater ( = 0.10) carcass ADG than steers fed RZC and CONT, while steers fed RZ were intermediate and not different. Steers fed RO had the greatest ( = 0.09) carcass G:F, while steers fed CONT had the least carcass G:F, 0.0875 and 0.0774, respectively. Steers fed RO and RC averaged 5.5 kg heavier ( = 0.09) HCW than steers fed RZC and CONT, while steers fed RZ were intermediate and not different. There were no treatment effects ( ≥ 0.32) on LM area, 12th rib fat, marbling score, KPH, carcass yield, or USDA yield grade and distribution. However, carcasses from steers fed RC had the greatest ( = 0.10) percentage grading USDA Select. There were no treatment effects ( ≥ 0.20) on shear force, intramuscular fat, pH, a*, and b*. Steaks from steers fed RO and RC had 11.4% greater ( = 0.08) cook loss than steaks from steers fed CONT and RZC, whereas steaks from steers fed RZ were intermediate and not different. Also, steaks from steers fed RC had 2.11 units greater ( = 0.03) L* values (i.e., were lighter) than steaks from steers fed RZ; steaks from steers fed CONT, RO, and RZC were intermediate. In feedlot steers, the addition of both Cr and Zn supplementation did not improve growth performance or meat quality when fed in combination with 28 d of RAC supplementation; however, RAC, fed alone or in combination with Cr, did increase HCW.

  16. Pharmacokinetics and effect of intravenous nalbuphine in weaned Holstein calves after surgical castration.

    PubMed

    Coetzee, J F; Lechtenberg, K F; Stock, M L; Kukanich, B

    2014-04-01

    The objective of this study was to investigate the pharmacokinetics and effect of nalbuphine administered intravenously to calves immediately prior to surgical castration. Ten healthy calves were randomly assigned to two treatments (n = 5): (i) 0.9% sodium chloride (CONT) placebo, (ii) nalbuphine hydrochloride (NAL) (0.4 mg/kg). Blood samples collected over 10 h postcastration were analyzed for nalbuphine and cortisol concentrations. Additionally, heart rate, respiratory rate, rectal temperature, and step count was compared between groups using a random-effects mixed model. Changes in behavior and attitude were assessed using a six-point ordinal scoring system and compared using chi-square analysis. Plasma NAL concentrations were only detectable for 3 h postadministration (T½ = 0.68 h; Range: 0.53-0.79 h). There was no effect of NAL treatment prior to castration on cortisol concentrations (P = 0.99), heart rate (P = 0.73), respiratory rate (P = 0.59), rectal temperature (P = 0.22), and step count (P = 0.08) but fewer calves showed signs of head shaking, kicking, and tail flicking in the NAL group compared with the CONT group (P = 0.036). Therefore, we conclude that a single intravenous injection of nalbuphine at 0.4 mg/kg reduced some pain-related behaviors but did not significantly eliminate the physiological signs of distress in calves after surgical castration. © 2013 John Wiley & Sons Ltd.

  17. Assessment of readiness to change in patients with osteoarthritis. development and application of a new questionnaire.

    PubMed

    Heuts, Peter H T G; de Bie, Rob A; Dijkstra, Arie; Aretz, Karin; Vlaeyen, Johan W S; Schouten, Hubert J A; Hopman-Rock, Marijke; van Weel, Chris; van Schayck, Constant P

    2005-05-01

    To develop a self-report measure for assessment of the stage of change in patients with osteoarthritis, in order to identify patients who would benefit from a self-management programme. According to the 'stages of change' model a questionnaire was developed with three groups of items corresponding to the precontemplation stage (Pre), the contemplation (Cont) and the action (Act) stage. Internal consistency and factor structure of this questionnaire were investigated by assessing Cronbach's alphas and by performing factor analysis. The questionnaire was offered to 273 patients who entered a randomized clinical trial on self-management in a general health care setting. Factor analysis revealed that most items corresponded to the a priori described groups, while some items were not loading on the presumed factor. In each subgroup some items were deleted, resulting in a 15-item questionnaire. After this item reduction Cronbach's alphas were 0.72 (Pre), 0.76 (Cont) and 0.79 (Act) and all factor loadings were satisfactory (above 0.35). Classification revealed some differences between parts of the total group, for example in the proportion of patients in the preparation stage (recruited by general practitioner = 33.6%; advertisement = 49.2%). The Stages of Change Questionnaire in Osteoarthritis, a 15-item questionnaire to assess the 'stage of change' of a patient with osteoarthritis showed good internal consistency and adequate factor structure. These findings warrant further studies on validity and applicability in a clinical context.

  18. Review of the Eustrophinae (Coleoptera, Tetratomidae) of America north of Mexico

    PubMed Central

    Pollock, Darren A.

    2012-01-01

    Abstract The Nearctic fauna (north of Mexico) of Eustrophinae is reviewed, and consists of the following five genera and 12 species: Pseudoholostrophus (Pseudoholostrophus) impressicollis (LeConte), Pseudoholostrophus (Holostrophinus) discolor (Horn), Holostrophus bifasciatus (Say), Eustrophus tomentosus Say, Eustrophopsis confinis (LeConte), Eustrophopsis bicolor (Fabricius), Eustrophopsis brunneimarginatus (Dury), Eustrophopsis indistinctus (LeConte), Eustrophopsis arizonensis (Horn), Eustrophopsis ornatus (Van Dyke), Eustrophopsis crowdyi sp. n., and Synstrophus repandus (Horn). A lectotype is designated for Eustrophus brunneimarginatus Dury. A key is given to separate genera and species, supplemented with illustrations of relevant features, including aedeagi of all Nearctic species of Eustrophopsis. Detailed distribution (including Mexican records) and natural history data are provided. PMID:22611332

  19. New Generation Strategic Submarine Study

    DTIC Science & Technology

    1977-01-01

    Ship Propulsion System . 111-22 III- A -6 Simplified Functional Diagram - Steam-Feed Flow System . 111-23 III- A -7...16 Aa Tabte XIZ- A -3 System (Element) Functional Analysis ResuZts--Engineering p Plant Subsystem SYSTEM (ELEMENT) FUNCTION Ll A . Ship Propulsion 1...FUNCTION A . Ship Propulsion (cont’d) 9. SSTG Throttle Valves * Provide frequency control of the ship’s service turbine generators, startup and

  20. Logic Programming in LISP.

    DTIC Science & Technology

    1981-01-01

    THIS PAGZ(Whan Doee Es tMord) Item 20 (Cont’d) ------ work in the area of artificial intelligence and those used in general program development into a...Controlling Gfile) IS. SECURITY CLASS. (of tis report) Same .,/ UNCLASSIFIED 13d. DECLASSIFICATION/ DOWN GRADING ..- ". .--- /A!CHEDULEI t I IS...logic programming with LISP for implementing intelligent data base query systems. Continued developments will allow for enhancements to be made to the

  1. Survey of Microcleaning Methods for Application to Army Coal-Fired Plants

    DTIC Science & Technology

    1989-02-01

    Authority (TVA) has successfully reduced its cost of controlling SOX by combining postcombustion flue gas desulfurization equipment with precombustion coal...effective way of meeting the new standards for SOl Several options are available, in- cluding flue gas desulfurization , fluidized bed combustors, and...are available, including flue gas desulfurization , fluidized bed combustors, and precombustion cleaning. This report (Cont’d.) 20 DISTRIBUTION

  2. Senegal: Background and U.S. Relations

    DTIC Science & Technology

    2012-04-11

    Politique et Révolution Passive. ‘Sopi’ or not ‘Sopi’?” Politique Africaine, December 2004. 12 See, for example, Abdou Latif Coulibaly, Contes et ...regional presence of violent extremist groups. Al Qaeda in the Islamic Maghreb (AQIM), an criminal- terrorist network with ties to Al Qaeda and roots...FTF_2010_Implementation_Plan_Senegal.pdf. 27 U.N. Development Program and Government of Senegal, Changement Climatique, Sécurité Alimentaire et Développement Humain

  3. Installation Restoration Program. Phase 2. Confirmation/Quantification. Stage 1

    DTIC Science & Technology

    1986-03-28

    Comftin,,,on Fvvem in.eea),a n dftl by bloe * numri ~A Problem Confirmation Study was conducted at Burlington Air National Guard BasE in Vermont. The...cont’d) 3. Characteristics(cont’d)- Biological Agent ( ) Volatile (4f Toxic (). Reactive ( ) 4. Toxicity: TLVs IDLHs 5. Special Hazards 6. Acute

  4. The Use of Monoterpenes as Kairomones by Ips latidens (LeConte) (Coleoptera: Scolytidae)

    Treesearch

    D.R. Miller; J.H. Borden

    1990-01-01

    The responses of Ips lutidens (LeConte) to multiple-funnel traps baited with various monoterpenes were determined in stands of lodgepole pine in British Columbia. ß-Phellandrene was attractive to I. lutidens in the absence of the pheromone ipsenol ß-Phellandrene increased the attraction of I. lutidens to...

  5. (S)-(+)-Ipsdienol: Interspecific Inhibition of Ips latidens (LeConte) by Ips pini (Say) (Coleoptera: Scolytidae)

    Treesearch

    Daniel R. Miller; John H. Borden

    1992-01-01

    In south-central British Columbia, the attraction of Ips latidens (LeConte) to its pheromone, ipsenol, was inhibited by (S)-(+)-ipsdienol, a pheromone for I. pini (Say). (R)-(-)-Ipsdienol had no effect on I. latidens. (S)-(+)-lpsdienol probably plays a role in interspecific communication between the two species...

  6. Fish passage research: S.O. Conte Anadromous Fish Research Laboratory

    USGS Publications Warehouse

    Garebedian, Steve

    2008-01-01

    The Leetown Science Center’s S.O. Conte Anadromous Fish Research Laboratory conducts basic and applied scientific studies of fish passage and migration to define underlying principles and relationships of fish behavior and hydraulics, and to develop integrated, predictive research that can be applied to a wide range of fish passage problems.

  7. Bem vindo - Portal Brasileiro de Dados Abertos

    Science.gov Websites

    Pular para o conteúdo Portal do Governo Brasileiro Ir para o conteúdo 1 Ir para o menu 2 Ir para a busca 3 Ir para o rodapé 4 dados.gov.br Portal Brasileiro de Dados Abertos Enviar feed twitter CÃ

  8. Home - Fundação Nacional de Saúde

    Science.gov Websites

    Pular para o conteúdo Portal do Governo Brasileiro Atualize sua Barra de Governo Ir para o conteúdo 1 Ir para o menu 2 Ir para a busca 3 Ir para o rodapé 4 Acessibilidade Acessibilidade Alto

  9. Larvae of the genus Eleodes (Coleoptera, Tenebrionidae): matrix-based descriptions, cladistic analysis, and key to late instars

    PubMed Central

    Smith, Aaron D.; Dornburg, Rebecca; Wheeler, Quentin D.

    2014-01-01

    Abstract Darkling beetle larvae (Coleoptera, Tenebrionidae) are collectively referred to as false wireworms. Larvae from several species in the genus Eleodes are considered to be agricultural pests, though relatively little work has been done to associate larvae with adults of the same species and only a handful of species have been characterized in their larval state. Morphological characters from late instar larvae were examined and coded to produce a matrix in the server-based content management system mx. The resulting morphology matrix was used to produce larval species descriptions, reconstruct a phylogeny, and build a key to the species included in the matrix. Larvae are described for the first time for the following 12 species: Eleodes anthracinus Blaisdell, Eleodes carbonarius (Say), Eleodes caudiferus LeConte, Eleodes extricatus (Say), Eleodes goryi Solier, Eleodes hispilabris (Say), Eleodes nigropilosus LeConte, Eleodes pilosus Horn, Eleodes subnitens LeConte, Eleodes tenuipes Casey, Eleodes tribulus Thomas, and Eleodes wheeleri Aalbu, Smith & Triplehorn. The larval stage of Eleodes armatus LeConte is redescribed with additional characters to differentiate it from the newly described congeneric larvae. PMID:25009429

  10. Intermittent-sprint performance and muscle glycogen after 30 h of sleep deprivation.

    PubMed

    Skein, Melissa; Duffield, Rob; Edge, Johann; Short, Michael J; Mündel, Toby

    2011-07-01

    The aim of this study was to determine the effects of 30 h of sleep deprivation on consecutive-day intermittent-sprint performance and muscle glycogen content. Ten male, team-sport athletes performed a single-day "baseline" session and two consecutive-day experimental trials separated either by a normal night's sleep (CONT1 and CONT2) or no sleep (SDEP1 and SDEP2). Each session included a 30-min graded exercise run and 50-min intermittent-sprint exercise protocol, including a 15-m maximal sprint every minute and self-paced exercise bouts of varying intensities. Muscle biopsies were extracted before and after exercise during the baseline session and before exercise on day 2 during experimental trials. Voluntary force and activation of the right quadriceps, nude mass, HR, core temperature, capillary blood lactate and glucose, RPE, and a modified POMS were recorded before, after, and during the exercise protocols. Mean sprint times were slower on SDEP2 (2.78±0.17 s) compared with SDEP1 (2.70±0.16 s) and CONT2 (2.74±0.15 s, P<0.05). Distance covered during self-paced exercise was reduced during SDEP2 during the initial 10 min compared with SDEP1 and during the final 10 min compared with CONT2 (P<0.05). Muscle glycogen concentration was lower before exercise on SDEP2 (209±60 mmol·kg dry weight) compared with CONT2 (274±54 mmol·kg dry weight, P=0.05). Voluntary force and activation were reduced on day 2 of both conditions; however, both were lower in SDEP2 compared with CONT2 (P<0.05). Sleep loss did not affect RPE but negatively affected POMS ratings (P<0.05). Sleep loss and associated reductions in muscle glycogen and perceptual stress reduced sprint performance and slowed pacing strategies during intermittent-sprint exercise for male team-sport athletes.

  11. Ultra-rapid earth rotation determination with VLBI during CONT11 and CONT14

    NASA Astrophysics Data System (ADS)

    Haas, Rüdiger; Hobiger, Thomas; Kurihara, Shinobu; Hara, Tetsuya

    2015-08-01

    In 2007 the Geospatial Information Authority of Japan (GSI) and the Onsala Space Observatory (OSO) started a collaboration project aiming at determining the earth rotation angle, usually expressed as UT1-UTC, in near real-time. In the beginning of this project dedicated one hour long one-baseline experiments were observed periodically using the VLBI stations Onsala (Sweden) and Tsukuba (Japan). The strategy is that the observed VLBI data are sent in real-time via the international optical fibre backbone to the correlator at Tsukuba where the data are correlated with a software correlator and analyzed in near-real time with the c5++ VLBI data analysis software, thus producing UT1-UTC results with very low latency. The latency between the observation at the stations and the determination of UT1-UTC is on the order of a few minutes, thus we can talk about an ultra-rapid determination of UT1-UTC. An offline version of this strategy was adopted in 2009 for the regular VLBI intensive series INT-2, organized by the International VLBI Service for Geodesy and Astrometry (IVS), that involves Wettzell (Germany) and Tsukuba. Since March 2010 the INT-2 is using real-time e-transfer, too, and since June 2010 also automated analysis. Starting in 2009 the ultra-rapid approach was applied to regular 24 hour long IVS VLBI-sessions that involve Tsukuba and Onsala, so that ultra-rapid UT1-UTC results can be produced already during ongoing VLBI-sessions. This strategy was successfully operated during the 15 days long continuous VLBI campaigns CONT11 and CONT14. In this presentation we give an overview of the ultra-rapid concept, present the results derived during CONT11 and CONT14, and compare these ultra-rapid results to results derived from post-processing

  12. Ultra-rapid earth rotation determination with VLBI during CONT11 and CONT14

    NASA Astrophysics Data System (ADS)

    Haas, Rüdiger; Hobiger, Thomas; Kurihara, Shinobu; Hara, Tetsuya

    2016-04-01

    In 2007 the Geospatial Information Authority of Japan (GSI) and the Onsala Space Observatory (OSO) started a collaboration project aiming at determining the earth rotation angle, usually expressed as UT1-UTC, in near real-time. In the beginning of this project dedicated one hour long one-baseline experiments were observed periodically using the VLBI stations Onsala (Sweden) and Tsukuba (Japan). The strategy is that the observed VLBI data are sent in real-time via the international optical fibre backbone to the correlator at Tsukuba where the data are correlated with a software correlator and analyzed in near-real time with the c5++ VLBI data analysis software, thus producing UT1-UTC results with very low latency. The latency between the observation at the stations and the determination of UT1-UTC is on the order of a few minutes, thus we can talk about an ultra-rapid determination of UT1-UTC. An offline version of this strategy was adopted in 2009 for the regular VLBI intensive series INT-2, organized by the International VLBI Service for Geodesy and Astrometry (IVS), that involves Wettzell (Germany) and Tsukuba. Since March 2010 the INT-2 is using real-time e-transfer, too, and since June 2010 also automated analysis. Starting in 2009 the ultra-rapid approach was applied to regular 24 hour long IVS VLBI-sessions that involve Tsukuba and Onsala, so that ultra-rapid UT1-UTC results can be produced already during ongoing VLBI-sessions. This strategy was successfully operated during the 15 days long continuous VLBI campaigns CONT11 and CONT14. In this presentation we give an overview of the ultra-rapid concept, present the results derived during CONT11 and CONT14, and compare these ultra-rapid results to results derived from post-processing.

  13. Fatigue Exacerbation by Interval or Continuous Exercise in Chronic Fatigue Syndrome.

    PubMed

    Sandler, Carolina X; Lloyd, Andrew R; Barry, Benjamin K

    2016-10-01

    The objective of this study is to determine whether the typical exacerbation of symptoms in patients with chronic fatigue syndrome (CFS) after a bout of exercise differs between high-intensity interval training (HIIT) or continuous (CONT) aerobic exercise of the same duration and mechanical work. Participants with specialist-diagnosed CFS performed two 20-min bouts of cycling in a randomized crossover study. The bouts were either moderate-intensity continuous (70% age-predicted HR maximum) or high-intensity interval exercise, separated by at least 2 wk. Self-report questionnaires capturing fatigue, the related symptoms, and actigraphy were collected across 2 d before and 4 d after the exercise. Comparisons between exercise bouts were made using paired sample t-tests. Fourteen moderately affected participants who were unable to work, but not bed bound, completed the study (nine female, 32 ± 10 yr, 67 ± 11 kg). Mechanical work was matched successfully between the exercise bouts (HIIT, 83,037, vs CONT, 83,348 J, P = 0.84). Mean HR (HIIT, 76% ± 5%, vs CONT, 73% ± 6% age-predicted HR maximum, P < 0.05) and RPE (6-20) in the legs (HIIT, 15.4 ± 1.4, vs CONT, 13.2 ± 1.2, P < 0.001) were higher for the interval compared with continuous exercise. Mean fatigue scores (0-10) were similar before each exercise challenge (HIIT, 4.5 ± 1.8, vs CONT, 4.1 ± 1.7, P = 0.43). Participants reported an increase in fatigue scores after both challenges (mean difference: HIIT, 1.0 ± 1.3, P < 0.01; CONT, 1.5 ± 0.7, P < 0.001), but these exacerbations in fatigue were not statistically or clinically different (P = 0.20). High-intensity interval exercise did not exacerbate fatigue any more than continuous exercise of comparable workload. This finding supports evaluation of HIIT in graded exercise therapy interventions for patients with CFS.

  14. Life History and Biology of Ips latidens (LeConte) (Coleoptera: Scolytidae)\\t

    Treesearch

    D.R. Miller; J.H. Borden

    1985-01-01

    The life history and biology of Ips latidens (LeConte) were investigated using bark-sandwich and whole-log rearing methods. In contrast with other Ips spp., some females initiated galleries under conditions of female-biased sex ratios, and sometimes 2 or more males were present in a gallery. In general, however, I....

  15. Polymorphism in Languria taedata LeConte, its occurrence in coastal Louisiana Spartina marshes, and clarification of some Motschulsky languriine types (Coleoptera: Erotylidae: Languriinae)

    USDA-ARS?s Scientific Manuscript database

    We clarify the diagnosis and geographic distribution of the widespread, variable eastern coastal species Languria taedata LeConte, 1854, in North America. After examining types and the range of variation and geographical distribution of the species, we propose synonymy of L. erythrocephalus Blatchle...

  16. Ground Controlled Approach Controller Training System (GCA-CTS) System Documentation.

    DTIC Science & Technology

    1980-06-01

    064010 OVER 72 Al NAVTRAEQUIPCEN 77-C-0162-3 TABLE 8. GCA-CTS PHRASES (CONT) Number Phrase of Identi- Number Repeats fier Phrase 90) 4 170040 THIS WILL...radians/second)( Becomes 0.0 degrees/second. 121 F-. 0 .,- NAVTRAEQUIPCE.: 77-C-nfi2-3 ?.1-t Ac7uires Vi5: al Contac- "’ith Runwav. If the current...variables: ITMP : temporary for source of speech output Files created/changed: None Files referenced: None Notes: None 388 I I4; r I’, Al ൐a7 190

  17. Influence of atmospheric pressure low-temperature plasma treatment on the shear bond strength between zirconia and resin cement.

    PubMed

    Ito, Yuki; Okawa, Takahisa; Fukumoto, Takahiro; Tsurumi, Akiko; Tatsuta, Mitsuhiro; Fujii, Takamasa; Tanaka, Junko; Tanaka, Masahiro

    2016-10-01

    Zirconia exhibits excellent strength and high biocompatibility in technological applications and it is has therefore been investigated for clinical applications and research. Before setting prostheses, a crown prosthesis inner surface is sandblasted with alumina to remove contaminants and form small cavities. This alumina sandblasting causes stress-induced phase transition of zirconia. Atmospheric-pressure low-temperature plasma has been applied in the dental industry, particularly for adhesives, as a surface treatment to activate the surface energy and remove contaminants. The purpose of this study was to examine the influence of atmospheric-pressure low-temperature plasma treatment on the shear bond strength between zirconia and adhesive resin cement. The surface treatment method was classified into three groups: untreated (Cont group), alumina sandblast treatment (Sb group), and atmospheric-pressure low-temperature plasma treatment (Ps group). Adhesive resin cement was applied to stainless steel and bonded to zirconia. Shear adhesion tests were performed after complete hardening of the cement. Multiple comparisons were performed using a one-way analysis of variance and the Bonferroni method. X-ray diffractometry was used to examine the change in zirconia crystal structure. Statistically significant differences were noted between the control and Sb groups and between the control and Ps groups. In contrast, no statistically significant differences were noted for the Ps and Sb bond strength. Atmospheric-pressure low-temperature plasma treatment did not affect the zirconia crystal structure. Atmospheric-pressure low-temperature plasma treatment improves the bonding strength of adhesive resin cement as effectively as alumina sandblasting, and does not alter the zirconia crystal structure. Copyright © 2016 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

  18. Anticipatory responses of catecholamines on muscle force production.

    PubMed

    French, Duncan N; Kraemer, William J; Volek, Jeff S; Spiering, Barry A; Judelson, Daniel A; Hoffman, Jay R; Maresh, Carl M

    2007-01-01

    Few data exist on the temporal relationship between catecholamines and muscle force production in vivo. The purpose of this study was to examine the influence of preexercise arousal on sympathoadrenal neurohormones on muscular force expression during resistance exercise. Ten resistance-trained men completed two experimental conditions separated by 7 days: 1) acute heavy resistance exercise protocol (AHREP; 6 x 10 repetitions parallel squats, 80% 1 repetition maximum) and 2) control (Cont; rest). Peak force (F(peak)) was recorded during a maximal isometric squat preceding each set and mean force (F(mean)) was measured during each set. Serial venous blood samples were collected before the AHREP and immediately preceding each set. Blood collection times were matched during Cont. Preexercise epinephrine (Epi), norepinephrine (NE), and dopamine (DA) increased (P or= 0.05) in muscular performance (F(peak), F(mean)) during AHREP and that five subjects (F(reducers)) had significant reductions in F(peak) and F(mean). Integrated area under the curve for Epi, NE, and F(peak) were greater (P < 0.02) for F(maintainers) than F(reducers). In conclusion, an anticipatory rise in catecholamines existed, which may be essential for optimal force production at the onset of exercise.

  19. Single and combined effects of beetroot juice and caffeine supplementation on cycling time trial performance.

    PubMed

    Lane, Stephen C; Hawley, John A; Desbrow, Ben; Jones, Andrew M; Blackwell, James R; Ross, Megan L; Zemski, Adam J; Burke, Louise M

    2014-09-01

    Both caffeine and beetroot juice have ergogenic effects on endurance cycling performance. We investigated whether there is an additive effect of these supplements on the performance of a cycling time trial (TT) simulating the 2012 London Olympic Games course. Twelve male and 12 female competitive cyclists each completed 4 experimental trials in a double-blind Latin square design. Trials were undertaken with a caffeinated gum (CAFF) (3 mg·kg(-1) body mass (BM), 40 min prior to the TT), concentrated beetroot juice supplementation (BJ) (8.4 mmol of nitrate (NO3(-)), 2 h prior to the TT), caffeine plus beetroot juice (CAFF+BJ), or a control (CONT). Subjects completed the TT (females: 29.35 km; males: 43.83 km) on a laboratory cycle ergometer under conditions of best practice nutrition: following a carbohydrate-rich pre-event meal, with the ingestion of a carbohydrate-electrolyte drink and regular oral carbohydrate contact during the TT. Compared with CONT, power output was significantly enhanced after CAFF+BJ and CAFF (3.0% and 3.9%, respectively, p < 0.01). There was no effect of BJ supplementation when used alone (-0.4%, p = 0.6 compared with CONT) or when combined with caffeine (-0.9%, p = 0.4 compared with CAFF). We conclude that caffeine (3 mg·kg(-1) BM) administered in the form of a caffeinated gum increased cycling TT performance lasting ∼50-60 min by ∼3%-4% in both males and females. Beetroot juice supplementation was not ergogenic under the conditions of this study.

  20. Swimming Pool Survey, Offutt AFB, Nebraska.

    DTIC Science & Technology

    1987-12-01

    8217. ’ -- , ,.R% ,, . . . ..- ’. .’ . Item #19 cont’d least daily to determine organic loading. (7) Quaternary ammonium algicides should be avoided; (8) Replace...combined with nitrogenous organic compounds from sweat, urine, or quaternary ammonium algicides . Choramines are less effective disinfectants, smell like... algicides should be avoided. Effective algal control is possible by maintaining from 1-2 mg/L free available chlorine and p+i between 7.4 and 7.8. H

  1. Sinterable Powders from Laser Driven Reactions

    DTIC Science & Technology

    1982-03-01

    using several shaping techniques. The Si powders were densified to precisely controlled levels designed to yield high density reaction bonded silicon...nitride (RBSN). -Nitriding kinetics were rapid at low temperatures because of the small particle sizes. Characteristic dimensions of RBSN micro ...b. Dispersion Test 90 c. Contact Angle Measurements 94 vi TABLE OF C014E1TS (cont.) PAGE 2. Results of Dispersion Test 94 a. Screening Tests 94 b

  2. Integrated Analysis Techniques for Command, Control, and Communications Systems. Volume 2. Applications

    DTIC Science & Technology

    1987-11-01

    video , blinking, or other visual cont rasts to high1- light events under cons’deration, and thereby reduce effective search tie). *By "bottleneck," we...CONFIDENCE [4.0] P EDIT/SEND I- PEDo 0.5]4I -P F O ( . 5 ) p _.LDIT SLNO :. R2402 "i Figure A-I. ADS-2 Report Sequence , p 119 -- NI%-.%., V’’- 4

  3. Verbenone interrupts attraction to host volatiles and reduces attack on Pinus tabuliformis (Pinaceae) by Dendroctonus valens (Coleoptera: Scolytidae) in the People's Republic of China

    Treesearch

    Jianghua Sun; Nancy Gillette; Zhengwan Miao; Zhongning Zhang Le Kang; Donald R. Owen; John D Stein

    2003-01-01

    The introduced red turpentine beetle, Dendroctonus valens LeConte, is one of the most economically important forest pests in the People's Republic of China, having killed more than 6 million pines in recent years. There is an urgent need to develop effective behavioral chemicals to monitor and control D. valens in the People...

  4. Effects of Streptomycin Administration on Increases in Skeletal Muscle Fiber Permeability and Size Following Eccentric Muscle Contractions.

    PubMed

    Hayao, Keishi; Tamaki, Hiroyuki; Nakagawa, Kouki; Tamakoshi, Keigo; Takahashi, Hideaki; Yotani, Kengo; Ogita, Futoshi; Yamamoto, Noriaki; Onishi, Hideaki

    2018-06-01

    The purpose of this study was to investigate the preventive effect of streptomycin (Str) administration on changes in membrane permeability and the histomorphological characteristics of damaged muscle fibers following eccentric contraction (ECC ). Eighteen 7-week-old male Fischer 344 rats were randomly assigned to three groups: control (Cont), ECC, and ECC with Str (ECC + Str). The tibialis anterior (TA) muscles in both ECC groups were stimulated electrically and exhibited ECC. Evans blue dye (EBD), a marker of muscle fiber damage associated with increased membrane permeability, was injected 24 hr before TA muscle sampling. The number of EBD-positive fibers, muscle fiber cross-sectional area (CSA), and roundness were determined via histomorphological analysis. The ECC intervention resulted in an increased fraction of EBD-positive fibers, a larger CSA, and decreased roundness. The fraction of EBD-positive fibers was 79% lower in the ECC + Str group than in the ECC group. However, there was no difference in the CSA and roundness of the EBD-positive fibers between the two ECC groups. These results suggest that Str administration can reduce the number of myofibers that increase membrane permeability following ECC, but does not ameliorate the extent of fiber swelling in extant EBD-positive fibers. Anat Rec, 301:1096-1102, 2018. © 2018 Wiley Periodicals, Inc. © 2018 Wiley Periodicals, Inc.

  5. Lycium Barbarum (Wolfberry) Reduces Secondary Degeneration and Oxidative Stress, and Inhibits JNK Pathway in Retina after Partial Optic Nerve Transection

    PubMed Central

    Li, Hongying; Liang, Yuxiang; Chiu, Kin; Yuan, Qiuju; Lin, Bin; Chang, Raymond Chuen-Chung; So, Kwok-Fai

    2013-01-01

    Our group has shown that the polysaccharides extracted from Lycium barbarum (LBP) are neuroprotective for retinal ganglion cells (RGCs) in different animal models. Protecting RGCs from secondary degeneration is a promising direction for therapy in glaucoma management. The complete optic nerve transection (CONT) model can be used to study primary degeneration of RGCs, while the partial optic nerve transection (PONT) model can be used to study secondary degeneration of RGCs because primary degeneration of RGCs and secondary degeneration can be separated in location in the same retina in this model; in other situations, these types of degeneration can be difficult to distinguish. In order to examine which kind of degeneration LBP could delay, both CONT and PONT models were used in this study. Rats were fed with LBP or vehicle daily from 7 days before surgery until sacrifice at different time-points and the surviving numbers of RGCs were evaluated. The expression of several proteins related to inflammation, oxidative stress, and the c-jun N-terminal kinase (JNK) pathways were detected with Western-blot analysis. LBP did not delay primary degeneration of RGCs after either CONT or PONT, but it did delay secondary degeneration of RGCs after PONT. We found that LBP appeared to exert these protective effects by inhibiting oxidative stress and the JNK/c-jun pathway and by transiently increasing production of insulin-like growth factor-1 (IGF-1). This study suggests that LBP can delay secondary degeneration of RGCs and this effect may be linked to inhibition of oxidative stress and the JNK/c-jun pathway in the retina. PMID:23894366

  6. Historical Winter Status of Three Upland Ammodramus Sparrows in South Carolina

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McNair, D.B.; Post, W.

    2000-10-01

    The wintering status of three upland sparrows were compared based upon collections. LeConte's sparrow was previously abundant during incursion years, but was less common on the coast. LeConte's and Henslow's were much more abundant 75-115 years ago. The later may result from breeding range reductions and habitat loss. The study demonstrates the usefulness of historical data.

  7. Nonhost angiosperm volatiles and verbenone protect individual ponderosa pines from attack by western pine beetle and red turpentine beetle (Coleoptera: Curculionidae, Scolytinae)

    Treesearch

    Christopher J. Fettig; Christopher P. Dabney; Stepehen R. McKelvey; Dezene P.W. Huber

    2008-01-01

    Nonhost angiosperm volatiles (NAV) and verbenone were tested for their ability to protect individual ponderosa pines, Pinus ponderosa Dougl. ex. Laws., from attack by western pine beetle (WPB), Dendroctonus brevicomis LeConte, and red turpentine beetle (RTB), Dendroctonus valens LeConte (Coleoptera: Curculionidae, Scolytinae). A combination of (

  8. Red Turpentine Beetle, Dendroctonus valens LeConte (Coleoptera: Scolytidae), Response to Host Semiochemicals in China

    Treesearch

    Jianghua Sun; Zhengwan Miao; Zhen Zhang; Zhongning Zhan; Nancy Gillette

    2004-01-01

    The response of the introduced red turpentine beetle, Dendroctonus valens LeConte, to host semiochemicals in Shanxi Province, China, was distinctly different from that reported in previous studies conducted in the western part of the native range of D. valens in the central Sierra Nevada, CA. This Þnding suggests either that...

  9. Drosophila contactin, a homolog of vertebrate contactin, is required for septate junction organization and paracellular barrier function.

    PubMed

    Faivre-Sarrailh, Catherine; Banerjee, Swati; Li, Jingjun; Hortsch, Michael; Laval, Monique; Bhat, Manzoor A

    2004-10-01

    Septate junctions (SJs) in epithelial and neuronal cells play an important role in the formation and maintenance of charge and size selective barriers. They form the basis for the ensheathment of nerve fibers in Drosophila and for the attachment of myelin loops to axonal surface in vertebrates. The cell-adhesion molecules NRX IV/Caspr/Paranodin (NCP1), contactin and Neurofascin-155 (NF-155) are all present at the vertebrate axo-glial SJs. Mutational analyses have shown that vertebrate NCP1 and its Drosophila homolog, Neurexin IV (NRX IV) are required for the formation of SJs. In this study, we report the genetic, molecular and biochemical characterization of the Drosophila homolog of vertebrate contactin, CONT. Ultrastructural and dye-exclusion analyses of Cont mutant embryos show that CONT is required for organization of SJs and paracellular barrier function. We show that CONT, Neuroglian (NRG) (Drosophila homolog of NF-155) and NRX IV are interdependent for their SJ localization and these proteins form a tripartite complex. Hence, our data provide evidence that the organization of SJs is dependent on the interactions between these highly conserved cell-adhesion molecules.

  10. Le Conte's sparrows breeding in Conservation Reserve Program fields: precipitation and patterns of population change

    USGS Publications Warehouse

    Igl, Lawrence D.; Johnson, Douglas H.

    1999-01-01

    The climate of the North American Great Plains is highly dynamic, with great year-to-year variability in precipitation and periodic, often extreme, wet and dry cycles (Bragg 1995). Drought is a major force of ecological disturbance on the Great Plains and has played a key role in directing the evolution of the grassland biota of this region (Knopf and Samson 1997). Although grassland birds may differ in their responses to enviromenental variations (Rotenberry and Wiens 1991), climatic variability and concomitant unpredictability of resources strongly influence populations of grassland birds across space and time (Wiens 1974, 1986; Cody 1985). Not surprisingly, breeding bird populations on the Great Plains are highly dynamic, exhibiting considerable annual variation in composition, abundance, and distribution (Johnson and Grier 1988, George et al. 1992, Zimmerman 1992, Igl and Johnson 1997). Recently, interest in grassland birds has increased with the recognition that many species are declining both continentally (Droege and Sauer 1994) and globally (Goriup 1988). Identification of the specific factors associated with grassland bird declines in North America, however, remains largely enigmatic (Herkert 1997), and it is complicated by the considerable annual fluctuations in grassland bird distribution and abundance (Igl and Johnson 1997). Although there is evidence that land-use changes on the breeding grounds may have contributed to grassland bird declines (e.g., Igl and Johnson 1997), there also is an indication that long-term drought conditions may have influenced recent population changes of some breeding birds on the Great Plains (Droege and Sauer 1989, Peterjohn and Sauer 1993, Bethke and Nudds 1995, Igl and Johnson 1997). Le Conte's Sparrow (Ammodramus leconteii) is a secretive grassland bird that breeds in central and southern Canada and the northcentral United States (Murray 1969). It winters primarily in the southern United States (Peterson 1980, 1990). Like populations of many grassland breeding birds in North America (Fretwell 1986, Igl and Johnson 1997), Le Conte's Sparrow populations exhibit numerical highs and lows depending on local moisture conditions (Peabody 1901, Stewart 1975, Knapton 1979, Zimmer 1979, Madden 1996). This observation, however, is based largely on anecdotal evidence or short-term observations. Long-term studies of Le Conte's Sparrow populations are limited. Le Conte's Sparrow is poorly represented on the North American Breeding Bird Survey (BBS) because of small sample sizes, poor coverage in the northern portion of its breeding range, and the species' furtive behavior (Sauer et al. 1995). Moreover, dramatic fluctuations in Le Conte's Sparrow abundance tend to obscure the species' long-term population trends on the BBS (Sauer et al. 1995). In this paper we examine long-term population changes of Le Conte's Sparrows breeding in perennial grassland fields enrolled in the Conservation Reserve Program (CRP) on the northern Great Plains. We discuss patterns of population change of Le Conte's Sparrows associated with changes in precipitation and moisture conditions.

  11. Comparaison des strategies discursives d'etayage dans un conte et un recit d'experiences oraux (Comparison of Scaffolding Discourse Strategies in an Oral Story and Personal Narrative).

    ERIC Educational Resources Information Center

    Rosat, Marie-Claude

    1998-01-01

    This study compared different strategies (questions, comments, reformulations, and repetitions) used by an adult in dialogue with 17 language impaired and 24 control preschool children. Two types of co-production (a tale and a personal account) were analyzed. The stability of the distribution of the various strategies in both situations is seen as…

  12. Reciprocal Relationships Between the Immune and Central Nervous System

    DTIC Science & Technology

    1990-05-01

    grovth factor B2, corticoster ", oids, IFN-y, conditioned taste aversion, schedule-cont rolled I Ibehavior, prostaglandin ., cPA yr s P oq/c.1oý w 19...on conditioned taste ’- & aversion, but they both inhibit the reductions in social exploration and scheddle-controlled behavior of rats injected...secreted by the pituitary gland. These findings probably at least partially explain why elderly persons cannot develop adequate fevers and are at risk

  13. Performance Testing of Twist Drills on AISI 4140 Alloy Steel

    DTIC Science & Technology

    1979-07-01

    AISI 4140 Annealed, RPM: 110, Feed Rate: 0.005 Ipr 2^ vi 1 LIST OF FIGURES (cont.) Figure Page 20. Maximum Height of Built-up Edge at Various...period. This investigation was conducted using only one kind of work material, AISI 4140 steel, annealed. The drill used for this investigation was a...HSS (M7), 0.5 inch diameter regular point, taper shank. AISI 4140 steel, annealed, belongs to a group of high strength materials relatively hard to

  14. An Evaluation of Reed Bed Technology to Dewater Army Wastewater Treatment Plant Sludge

    DTIC Science & Technology

    1993-09-01

    speculated that the plants produced "root exudations" that were active against pathogens, and that the plants specifically showed an affinity for cadmium , zinc...Schwenksville, PA Topton Sewage Treatment Topton. PA Wabash WWTP Wabash . IN Wallingford Fire District #lWastewater Treatment Plant Wallingford. VT...Navy Group 06/88 Tom Severance Security 207-963-5534 Winter Harbour. ME Wabash WWTP. IN 09/91 Vincent J. Bauco 219-563-2941 20 Table 4 (Cont’d

  15. Drug Development of the Antimalarial Agent Artemisinin: Total Synthesis, Analog Synthesis, and Structure-Activity Relationship Studies

    DTIC Science & Technology

    1990-08-15

    16. SUPPLEMENTARY NOTATION 17 COSATi CODES FiELD 07 06 CROUP 03 01 SUB-GROUP IB SUBJECT TERMS (Cont/nu* on rtvtnt if ntctiwy *ne identity b ...number of requisite substituents resulted in the synthesis of ring cleaved analogs and partial structures of artemisinin: (+)-C/D, (+)-A/ B /C, (+)-A/C...in the preparation of the unstable aldehyde 2, and in commendable fashion others have employed an enol ether photo-oxygenation as entry to that

  16. The Annual Department of Defense Procurement Research Symposium (5th), held 17-19 Nov 76, Monterey, California.

    DTIC Science & Technology

    1976-11-01

    Federal Procurement Policy Mr. Fred Bunke - Assistant Commissioner for Procurement, General Services Administration 5:00 - 6:00 p.m. No host cocktail party...Research Specialist General Services Administration -3- 71 Symposium Agenda 8:30 - 10:15 a.m. Concurrent Session II (cont’d.) WORKING GROUP E... Services Administration . From 1950 - 1960, Mr. Bunke held various supply and procurement billets at sea and ashore as a Navy Supply Corps Officer. From

  17. Kinetic modelling of methane production during bio-electrolysis from anaerobic co-digestion of sewage sludge and food waste.

    PubMed

    Prajapati, Kalp Bhusan; Singh, Rajesh

    2018-05-10

    In present study batch tests were performed to investigate the enhancement in methane production under bio-electrolysis anaerobic co-digestion of sewage sludge and food waste. The bio-electrolysis reactor system (B-EL) yield more methane 148.5 ml/g COD in comparison to reactor system without bio-electrolysis (B-CONT) 125.1 ml/g COD. Whereas bio-electrolysis reactor system (C-EL) Iron Scraps amended yield lesser methane (51.2 ml/g COD) in comparison to control bio-electrolysis reactor system without Iron scraps (C-CONT - 114.4 ml/g COD). Richard and Exponential model were best fitted for cumulative methane production and biogas production rates respectively as revealed modelling study. The best model fit for the different reactors was compared by Akaike's Information Criterion (AIC) and Bayesian Information Criterion (BIC). The bioelectrolysis process seems to be an emerging technology with lesser the loss in cellulase specific activity with increasing temperature from 50 to 80 °C. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Tributyltin contributes in reducing the vascular reactivity to phenylephrine in isolated aortic rings from female rats.

    PubMed

    Rodrigues, Samya Mere L; Ximenes, Carolina F; de Batista, Priscila R; Simões, Fabiana V; Coser, Pedro Henrique P; Sena, Gabriela C; Podratz, Priscila L; de Souza, Leticia N G; Vassallo, Dalton V; Graceli, Jones B; Stefanon, Ivanita

    2014-03-21

    Organotin compounds such as tributyltin (TBT) are used as antifouling paints by shipping companies. TBT inhibits the aromatase responsible for the transformation of testosterone into estrogen. Our hypothesis is that TBT modulates the vascular reactivity of female rats. Female Wistar rats were treated daily (Control; CONT) or TBT (100 ng/kg) for 15 days. Rings from thoracic aortas were incubated with phenylephrine (PHE, 10(-10)-10(-4) M) in the presence and absence of endothelium, and in the presence of N(G)-Nitro-L-Arginine Methyl Ester (L-NAME), tetraethylammonium (TEA) and apocynin. TBT decreased plasma levels of estrogen and the vascular response to PHE. In the TBT group, the vascular reactivity was increased in the absence of endothelium, L-NAME and TEA. The decrease in PHE reactivity during incubation with apocynin was more evident in the TBT group. The sensitivity to acetylcholine (ACh) and sodium nitroprusside (SNP) was reduced in the TBT group. TBT increased collagen, reduced α1-smooth muscle actin. Female rats treated with TBT for 15 days showed morphology alteration of the aorta and decreased their vascular reactivity, probably due to mechanisms dependent on nitric oxide (NO) bioavailability, K(+) channels and an increase in oxidative stress. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  19. Hydrogel-embedded nanocrystalline hydroxyapatite granules (elastic blocks) based on a cross-linked polyvinylpyrrolidone as bone grafting substitute in a rat tibia model.

    PubMed

    Dau, Michael; Ganz, Cornelia; Zaage, Franziska; Frerich, Bernhard; Gerber, Thomas

    2017-01-01

    The aim of this study was to examine the in vivo characteristics and levels of integration and degradation of a ready-to-use bone grafting block with elastic properties (elastic block) for the use in surgery. Thirty-six male Wistar rats underwent surgical creation of a well-defined bone defect in the tibia. All created defects - one per animal - were filled with an unsintered nanocrystalline hydroxyapatite embedded either with a non-cross-linked hydrogel carrier (CONT, n=18) or a cross-linked hydrogel carrier (elastic block [EB], n=18) based on polyvinylpyrrolidone (PVP) and silica sol, respectively. The animals were killed after 12 (n=12), 21 (n=12) and 63 days (n=12). The bone formation and defect healing were quantified by histomorphometric measurements made in paraffin sections. Additionally, immunohistochemical (tartrate-resistant acid phosphatase [TRAP] and alkaline phosphatase [aP]), antibody-based examinations (CD68) and energy-dispersive x-ray scattering measurements of silica atom concentration were carried out. A larger remaining bone defect area overall was observed in EB after 12 days and 21 days. After 63 days, similar areas of remaining bone defects were found. The amount of the remaining carrier material in EB overall was higher at all times. In CONT no residual carrier material was found at 12 days and later. CD68 analyses showed significantly lower level of CD68-positive marked cells after 21 days in CONT, and nonsignificant differences at 12 and 63 days, respectively. Additionally, a significantly higher level of aP-positive marked cells was observed in CONT after 12 days. Later on, the levels of aP-positive marked cells were slightly higher in EB (21 and 63 days). Furthermore, no significant differences regarding the level of TRAP-positive marked cells in each group were observed. The bone substitute (EB) with the cross-linked PVP-based hydrogel carrier leads at the beginning to a higher amount of remaining carrier material and remaining bone substitute. This delayed degradation is supposed to be the reason for the observed lower level of bone remodeling and is caused by the irradiation changes (cross links) in the structure in PVP.

  20. Hydrogel-embedded nanocrystalline hydroxyapatite granules (elastic blocks) based on a cross-linked polyvinylpyrrolidone as bone grafting substitute in a rat tibia model

    PubMed Central

    Dau, Michael; Ganz, Cornelia; Zaage, Franziska; Frerich, Bernhard; Gerber, Thomas

    2017-01-01

    Purpose The aim of this study was to examine the in vivo characteristics and levels of integration and degradation of a ready-to-use bone grafting block with elastic properties (elastic block) for the use in surgery. Materials and methods Thirty-six male Wistar rats underwent surgical creation of a well-defined bone defect in the tibia. All created defects – one per animal – were filled with an unsintered nanocrystalline hydroxyapatite embedded either with a non-cross-linked hydrogel carrier (CONT, n=18) or a cross-linked hydrogel carrier (elastic block [EB], n=18) based on polyvinylpyrrolidone (PVP) and silica sol, respectively. The animals were killed after 12 (n=12), 21 (n=12) and 63 days (n=12). The bone formation and defect healing were quantified by histomorphometric measurements made in paraffin sections. Additionally, immunohistochemical (tartrate-resistant acid phosphatase [TRAP] and alkaline phosphatase [aP]), antibody-based examinations (CD68) and energy-dispersive x-ray scattering measurements of silica atom concentration were carried out. Results A larger remaining bone defect area overall was observed in EB after 12 days and 21 days. After 63 days, similar areas of remaining bone defects were found. The amount of the remaining carrier material in EB overall was higher at all times. In CONT no residual carrier material was found at 12 days and later. CD68 analyses showed significantly lower level of CD68-positive marked cells after 21 days in CONT, and nonsignificant differences at 12 and 63 days, respectively. Additionally, a significantly higher level of aP-positive marked cells was observed in CONT after 12 days. Later on, the levels of aP-positive marked cells were slightly higher in EB (21 and 63 days). Furthermore, no significant differences regarding the level of TRAP-positive marked cells in each group were observed. Conclusion The bone substitute (EB) with the cross-linked PVP-based hydrogel carrier leads at the beginning to a higher amount of remaining carrier material and remaining bone substitute. This delayed degradation is supposed to be the reason for the observed lower level of bone remodeling and is caused by the irradiation changes (cross links) in the structure in PVP. PMID:29066890

  1. Neural complexity in patients with poststroke depression: A resting EEG study.

    PubMed

    Zhang, Ying; Wang, Chunfang; Sun, Changcheng; Zhang, Xi; Wang, Yongjun; Qi, Hongzhi; He, Feng; Zhao, Xin; Wan, Baikun; Du, Jingang; Ming, Dong

    2015-12-01

    Poststroke depression (PSD) is one of the most common emotional disorders affecting post-stroke patients. However, the neurophysiological mechanism remains elusive. This study was aimed to study the relationship between complexity of neural electrical activity and PSD. Resting state eye-closed electroencephalogram (EEG) signals of 16 electrodes were recorded in 21 ischemic poststroke depression (PSD) patients, 22 ischemic poststroke non-depression (PSND) patients and 15 healthy controls (CONT). Lempel-Ziv Complexity (LZC) was used to evaluate changes in EEG complexity in PSD patients. Statistical analysis was performed to explore difference among different groups and electrodes. Correlation between the severity of depression (HDRS) and EEG complexity was determined with pearson correlation coefficients. Receiver operating characteristic (ROC) and binary logistic regression analysis were conducted to estimate the discriminating ability of LZC for PSD in specificity, sensitivity and accuracy. PSD patients showed lower neural complexity compared with PSND and CONT subjects in the whole brain regions. There was no significant difference among different brain regions, and no interactions between group and electrodes. None of the LZC significantly correlated with overall depression severity or differentiated symptom severity of 7 items in PSD patients, but in stroke patients, significant correlation was found between HDRS and LZC in the whole brain regions, especially in frontal and temporal. LZC parameters used for PSD recognition possessed more than 85% in specificity, sensitivity and accuracy, suggesting the feasibility of LZC to serve as screening indicators for PSD. Increased slow wave rhythms were found in PSD patients and clearly correlation was confirmed between neuronal complexity and spectral power of the four EEG rhythms. Lesion location of stroke patients in the study distributed in different brain regions, and most of the PSD patients were mild or moderate in depressive severity. Compared with conventional spectral analysis, complexity of neural activity using LZC was more sensitive and stationary in the measurement of abnormal brain activity in PSD patients and may offer a potential approach to facilitate clinical screening of this disease. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  2. Proliferative capability of parietal and zymogen cells.

    PubMed Central

    Chen, K Y; Withers, H R

    1975-01-01

    Six to eight week old male mice of C3Hf/Bu strain were killed and studied at various times from 30 minutes to 30 days after tritiated thymidine (3H-TdR) injection. Labelling of parietal and zymogen cells was observed in autoradiographic histological specimens. There were 590 +/- 22 gastric glands per circumference at the body of the stomach. Parietal cells were counted as 16-2 (14-0-18-4) per gland or 9600 per circumference. There were 11-4 (9-4-13-7) zymogen cells per gland or 6700 per circumference. Two labelled immature parietal cells per circumference were seen 30 minutes after 3H-TdR injection, equivalent to a ratio of 1:5000; more mature labelled parietal cells were seen at later times up to 30 days. There was evidence for proliferation during maturation and downward migration of cells toward the body and the lower part of the gastric gland. Our data support earlier evidence that immature parietal cells constantly supply mature parietal cells through migration from a proliferative zone. Whether the parietal cells are derived from the same stem cell compartment as surface epithelium cells is unclear at the present time. An average of 2-6 zymogen cells per circumference, or 1:2500, was found to be labelled. While most zymogen cells were not proliferating, cells entered the proliferating cycle at random. Based on the findings reported in this paper and the radiation responses of both parietal and zymogen cells, it is postulated that they form part of a slow renewal system. Images Fig. 1 (cont.) Fig. 1 (cont.) Fig. 1 (cont.) Fig. 1 Fig. 2 (cont.) Fig. 2 (cont.) Fig. 2 PMID:1213947

  3. Characterization of fibroblasts from hypertrophied right ventricle of pulmonary hypertensive rats.

    PubMed

    Imoto, Keisuke; Okada, Muneyoshi; Yamawaki, Hideyuki

    2018-06-02

    Pulmonary arterial hypertension (PAH), which is characterized by an elevation of pulmonary arterial resistance, leads to a lethal right heart failure. It is an urgent issue to clarify the pathogenesis of PAH-induced right heart failure. The present study aimed to elucidate the characteristics of cardiac fibroblasts (CFs) isolated from hypertrophied right ventricles of monocrotaline (MCT)-induced PAH model rats. CFs were isolated from the right ventricles of MCT-injected rats (MCT-CFs) and saline-injected control rats (CONT-CFs). Expression of α-smooth muscle actin and collagen type I in MCT-CFs was lower than that in CONT-CFs. On the other hand, proliferation, migration, and matrix metalloproteinase (MMP)-9 production were significantly enhanced in MCT-CFs. In MCT-CFs, phosphorylation of extracellular signal-regulated kinase (ERK) 1/2, c-Jun N-terminal kinase (JNK), and Ca 2+ /calmodulin-dependent protein kinase (CaMK) II was significantly enhanced. In addition to mRNA expression of Orai1, a Ca 2+ release-activated Ca 2+ channel, and stromal interaction molecules (STIM) 1, an endoplasmic reticulum Ca 2+ sensor, the associated store-operated Ca 2+ entry (SOCE) was significantly higher in MCT-CFs than CONT-CFs. Pharmacological inhibition of ERK1/2 pathway prevented the enhanced proliferation of MCT-CFs. The enhanced migration of MCT-CFs was prevented by a pharmacological inhibition of ERK1/2, JNK, CaMKII, or SOCE pathway. The enhanced MMP-9 production in MCT-CFs was prevented by a pharmacological inhibition of ERK1/2, CaMKII, or SOCE pathway but not JNK. The present results suggested that MCT-CFs exhibit proliferative and migratory phenotypes perhaps through multiple signaling pathways. This study for the first time determined the characteristics of CFs isolated from hypertrophied right ventricles of MCT-induced PAH model rats.

  4. Reevaluation of Chalcophora angulicollis (LeConte) and Chalcophora virginiensis (Drury) with a review and key to the North American species of Chalcophora DeJean (Coleoptera: Buprestidae)

    Treesearch

    Crystal A. Maier; Michael A. Ivie

    2013-01-01

    Chalcophora angulicollis (LeConte) and Chalcophora virginiensis (Drury) are shown to be valid allopatric species in the western and eastern forests of North America, respectively. The historic uncertainty regarding their status is reviewed, and new characters of the aedeagus, penultimate maxillary palpomere, and elytral serrations are utilized for their identification...

  5. The complete mitochondrial genome of the desert darkling beetle Asbolus verrucosus (Coleoptera, Tenebrionidae).

    PubMed

    Rider, Stanley Dean

    2016-07-01

    The complete mitochondrial genome of the desert darkling beetle Asbolus verrucosus (LeConte, 1851) was sequenced using paired-end technology to an average depth of 42,111× and assembled using De Bruijn graph-based methods. The genome is 15,828 bp in length and conforms to the basal arthropod mitochondrial gene composition with the same gene orders and orientations as other darkling beetle mitochondria. This arrangement includes a control region, 22 tRNA genes, 2 rRNA genes and 13 protein-coding genes. The main coding strand is probably replicated as the lagging strand (GC skew of -0.36 and AT skew of +0.19). Phylogenomics analyses are consistent with taxonomic classifications and indicate that Tenebrio molitor is the closest relative that has a completely sequenced mitochondrial genome available for analysis. This is the first fully assembled mitogenome sequence for a darkling beetle in the subfamily Pimeliinae and will be useful for population studies on members of this ecologically important group of beetles.

  6. Cattle with increased severity of bovine respiratory disease complex exhibit decreased capacity to protect against histone cytotoxicity.

    PubMed

    Matera, J A; Wilson, B K; Hernandez Gifford, J A; Step, D L; Krehbiel, C R; Gifford, C A

    2015-04-01

    Bovine respiratory disease complex (BRDC) is the leading cause of morbidity and mortality in feedlot cattle. Significant inflammation and lesions are often observed in lungs of infected cattle. During acute inflammatory responses, histones contribute to mortality in rodents and humans and serum proteins can protect against histone-induced cytotoxicity. We hypothesized that cattle experiencing chronic or fatal cases of BRDC have reduced ability to protect against cytotoxic effects of histones. Serum samples were collected from 66 bull calves at the time of normal feedlot processing procedures. Animals were retrospectively assigned to groups consisting of calves never treated for BRDC (control [CONT]; n = 10), calves treated with antimicrobials once for BRDC (1T; n = 16), calves treated twice for BRDC (2T; n = 13), calves treated 3 times for BRDC (3T; n = 14), or calves treated 4 times for BRDC (4T; n = 13). Samples were also collected each time animals received antimicrobial treatment; animals within a group were further sorted by calves that recovered and calves that died to test histone cytotoxicity. Bovine kidney cells were cultured in duplicate in 96-well plates and exposed to 0 or 50 μg/mL of total histones for 18 h with 1% serum from each animal. Cell viability was assessed by the addition of resazurin for 6 h followed by fluorescent quantification. Fluorescent values from serum alone were subtracted from values obtained for histone treatment for each animal. Serum from CONT, 1T, and 2T at initial processing all exhibited a similar (P > 0.10) response to histone treatment with fluorescent values of -312 ± 557, -1,059 ± 441, and -975 ± 489, respectively. However, 3T and 4T demonstrated an impaired capacity (P < 0.05) to protect against histones (-2,778 ± 471 and -3,026 ± 489) at initial processing when compared to the other groups. When sorted by mortality within group, calves that were treated twice and recovered (-847 ± 331) demonstrated a greater (P < 0.05) protective capacity than calves that were treated twice and died (-2,264 ± 412), indicating that calves that contract BRDC and ultimately die might have reduced protective capacity against histone cytotoxicity. Results suggest that calves that require multiple treatments for BRDC have reduced ability to protect against cytotoxicity of histones. Understanding the primary mechanism responsible for protecting against histone cytotoxicity could lead to improved identification of animals susceptible to severe cases of BRDC, improved focus and use of available resources, or better treatments for severe cases of BRDC

  7. A Western Corn Rootworm Cadherin-like Protein is not Involved in the Binding and Toxicity of Cry34/35Ab1 and Cry3Aa Bacillus Thuringiensis Proteins

    USDA-ARS?s Scientific Manuscript database

    The western corn rootworm (WCR) Diabrotica virgifera virgifera LeConte is an important insect pest of corn. Bacillus thuringiensis (Bt) insecticidal proteins Cry3Aa (as mCry3A) and Cry34Ab1/Cry35Ab1 have been expressed in transgenic corn and are used to control the insect in the U.S. To date, there ...

  8. Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism.

    PubMed

    Kaseda, Ryohei; Tsuchida, Yohei; Yang, Hai-Chun; Yancey, Patricia G; Zhong, Jianyong; Tao, Huan; Bian, Aihua; Fogo, Agnes B; Linton, Mac Rae F; Fazio, Sergio; Ikizler, Talat Alp; Kon, Valentina

    2018-01-27

    Our aim was to evaluate lipid trafficking and inflammatory response of macrophages exposed to lipoproteins from subjects with moderate to severe chronic kidney disease (CKD), and to investigate the potential benefits of activating cellular cholesterol transporters via liver X receptor (LXR) agonism. LDL and HDL were isolated by sequential density gradient ultracentrifugation of plasma from patients with stage 3-4 CKD and individuals without kidney disease (HDL CKD and HDL Cont , respectively). Uptake of LDL, cholesterol efflux to HDL, and cellular inflammatory responses were assessed in human THP-1 cells. HDL effects on inflammatory markers (MCP-1, TNF-α, IL-1β), Toll-like receptors-2 (TLR-2) and - 4 (TLR-4), ATP-binding cassette class A transporter (ABCA1), NF-κB, extracellular signal regulated protein kinases 1/2 (ERK1/2) were assessed by RT-PCR and western blot before and after in vitro treatment with an LXR agonist. There was no difference in macrophage uptake of LDL isolated from CKD versus controls. By contrast, HD CKD was significantly less effective than HDL Cont in accepting cholesterol from cholesterol-enriched macrophages (median 20.8% [IQR 16.1-23.7] vs control (26.5% [IQR 19.6-28.5]; p = 0.008). LXR agonist upregulated ABCA1 expression and increased cholesterol efflux to HDL of both normal and CKD subjects, although the latter continued to show lower efflux capacity. HDL CKD increased macrophage cytokine response (TNF-α, MCP-1, IL-1β, and NF-κB) versus HDL Cont . The heightened cytokine response to HDL CKD was further amplified in cells treated with LXR agonist. The LXR-augmentation of inflammation was associated with increased TLR-2 and TLR-4 and ERK1/2. Moderate to severe impairment in kidney function promotes foam cell formation that reflects impairment in cholesterol acceptor function of HDL CKD . Activation of cellular cholesterol transporters by LXR agonism improves but does not normalize efflux to HDL CKD . However, LXR agonism actually increases the pro-inflammatory effects of HDL CKD through activation of TLRs and ERK1/2 pathways.

  9. Mississippi River Headwaters Lakes in Minnesota, Low Flow Review

    DTIC Science & Technology

    1990-10-01

    CONTENTS Item Page OBJECTIVES OF LOW FLOW REVIEW 1 AUTHORITY FOR THIS LOW FLOW REVIEW 1 PROJECT AUTHORIZATION 1 AUTHORIZED PROJECT PURPOSES 2 WATER...OF CONTENTS (CONT) Item Page CONSUMPTIVE WATER USES 26 CORPS OF ENGINEERS WATER SUPPLY POLICIES 27 INTRODUCTION 27 EMERGENCY WATER SUPPLY 27 PLANNING...EFFECTS OF EMERGENCY 45 SUPPLEMENTAL FLOWS ii TABLE OF CONTENTS (CONT) Item Page LOW FLOW PLANNING BY OTHERS 46 LONG-RANGE WATER USE PLANNING FOR THE TWIN

  10. Progress in the Global Standardization of Gravity: An Analysis of the Woollard and Rose International Gravity Values,

    DTIC Science & Technology

    1980-12-01

    graviineters by the Air Force 1281st Geodetic Snuadron (’ halen , unpublished) at most of the same sites in 1965 are shown relative to the IGS!1 71 values...cont.) United States (cont.) Woollard and gnma IGSN 71 Diff GW 77A Woods Hole BM 980.3271 .312 49* -14.61 MI CI! I( VAN Detroit WA 116 "K" Willow Run

  11. Selection for Cry3Bb1 resistance in a genetically diverse population of nondiapausing western corn rootworm (Coleoptera: Chrysomelidae).

    PubMed

    Oswald, Kenneth J; French, B Wade; Nielson, Chad; Bagley, Mark

    2011-06-01

    Five short-diapause laboratory lines of western corn rootworm, Diabrotica virgifera virgifera LeConte (Coleoptera: Chrysomelidae), were selected for resistance to MON863, a variety of corn genetically modified with the Bacillus thuringiensis Berliner (Bt) transgene that expresses the Cry3Bb1 delta-endotoxin. Three of the selected lines were developed by incremental increase in the duration of exposure to MON863 over 11 generations (moderate selected lines). Two selected lines were developed from a control group by constant exposure to MON863 for at least 14 d posthatch over seven generations (intense selected lines). At the end of the experiment, survivorship, as measured by adult emergence, was approximately 4 times higher in each of the selected lines reared on MON863 compared with control lines. Estimates of realized heritabilities (h2) were 0.16 and 0.15 for the moderate and intense selected lines, respectively, and are consistent with h2 estimates reported previously from a variety of pest insects. These lines provide data necessary for evaluating the potential for Bt resistance within diabroticite beetles and will be useful for developing improved insect resistance management strategies.

  12. Effectiveness of intrauterine treatment with cephapirin in dairy cows with purulent vaginal discharge.

    PubMed

    Tison, N; Bouchard, E; DesCôteaux, L; Lefebvre, R C

    2017-02-01

    The objective of this study was to assess the efficacy of cephapirin intrauterine treatment preceding a timed artificial insemination protocol in lactating dairy cows with purulent vaginal discharges (PVDs). Holstein dairy cows (n = 1247) from 18 herds were enrolled in a controlled randomized clinical trial. At 34 days in milk (DIM; ±7 days), cows had a genital examination (transrectal palpation, vaginoscopy, and uterine bacteriology). They were randomly assigned to either the control group (CONT, no treatment) or the treatment group (CEPH) consisting of 1 intrauterine infusion of 500-mg cephapirin benzathine (RCL) (Metricure, Merck Animal Health, Montreal, Canada) regardless of the uterine health status. All cows were systematically enrolled in a presynch-ovsynch protocol for the first insemination. A second genital examination was made 2 weeks later. Cows that received any systemic or local antibiotics 10 days prior sampling to the end of the synchronization protocol were excluded from the study. Reproductive data of cows were collected for at least 300 DIM, entered in a databank, and validated (health record management software, DSAHR). Pregnancy diagnosis was done by transrectal palpation at the routinely scheduled veterinarian visits. On the basis of the highest sum of sensibility and specificity for pregnancy status at 120 DIM, the optimal cutoff for vaginal discharge score was determined as the presence of cloudy discharge with or without purulent material (PVD+, score 2). With a prevalence of 21.6% at 34 DIM, PVD+ was detrimental to the first-service conception rate (FSCR; PVD+: 26 ± 5%; PVD-: 40 ± 3%; P = 0.02). The negative effect of PVD+ was indicated by a hazard ratio of 0.72 (chi-square = 8.58; P < 0.01; 95% confidence interval = 0.56-0.91). Treatment with cephapirin was associated with a significant improvement of the FSCR in PVD+ cows (PVD+ CEPH: 36 ± 5%, PVD+ CONT: 23 ± 5%; P < 0.05), although it did not produce a considerable clinical cure based on the second examination. Thus, a longer period of time following treatment may be needed to properly assess the efficacy of intrauterine treatment in PVD+ cows. In conclusion, cephapirin intrauterine treatment in PVD+ cows at 34 DIM considerably improves reproductive performance compared with untreated PVD+ cows. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Aspects of Industrial Water Treatment.

    DTIC Science & Technology

    1978-02-01

    Biochemical oxygen demand, Nitrate (as I) Cyanide, total 5- d (DOD 5 ) Nitr$te (a N) Cyanide amenable to i Chealc€l oxygen deuma! (COD)) chlorination...for Industrial ProcessWaters * o s .o. . o , ,,. . . , s o , , , , 26 Is CON~TfNTS (Cont’dI TAMLE (Cont’ d ) 10 Limiting Concentration Ranges...the United States are graphically presented in Figures I and 2. D . Z C O’ M ITUMMS OJT WATM U 1. Untreated feedwater can cause numerous problems in

  14. Structural Modeling and Response of Command, Control and Communication Shelter Systems for Event DICE THROW.

    DTIC Science & Technology

    1980-03-01

    Construction ... ........... ... 71 7 FkAEC"IWAG FitAZbL~ai-am naJ" LIST OF ILLUSTRATIONS (CONT’D) Figure Page 2.26 Grid Point System for AN/TRC-145...systems consists of a basic shelter structure whose side walls are of sandwich construction with internal stiffeners. Channel extrusions along each...free edge of the shelter provide additional strength and stiffening. The shelters contain electronic equipment racks of open framework construction using

  15. Feasibility Study on CNC Multioperation Grinding of Jet Engine Components Using Force Sensing Adaptive Control.

    DTIC Science & Technology

    1982-09-30

    OF TI4IS PIAGE(,,aW Date Eateed) cont. block 20: .... differential wheelwear and thereby prevent form errors. Wheel sharpness can also be monitored to...80 5. NOMENCLATURE V = Work surface speed (m/s) w Nw = Work speed (RPM) Vs = Wheel surface speed (m/sec) Ns = Wheel ...speed (RPM) Vt = Traverse speed (m/sec) 0 = Work diameter (mm)W D = Wheel diameter (mm) z= Dress lead (um/rev) c = 2*diamond depth-of-dress (um) d

  16. The effect of prophylaxis method on microtensile bond strength of indirect restorations to dentin.

    PubMed

    Soares, C J; Pereira, J C; Souza, S J B; Menezes, M S; Armstrong, S R

    2012-01-01

    The aim of this study was to evaluate the effect of different materials used for dentin prophylaxis on the microtensile bond strengths (μTBS) of adhesively cemented indirect composite restorations. Sixty bovine incisors had the buccal surface ground with wet #600-grit silicon carbide abrasive paper to obtain a flat exposed superficial dentin and were submitted to different prophylaxis protocols, as follows: 3% hydrogen peroxide (HydP); 0.12% chlorhexidine (Chlo); sodium bicarbonate jet (SodB); 50-μm aluminum oxide air abrasion (AirA); pumice paste (PumP), and control group-water spray (Cont). After prophylaxis protocols a resin composite block (3.0 mm × 5.0 mm × 5.0 mm) was adhesively cemented using dual resin cement (Rely X ARC). After 24 hours of water storage, specimens were serially sectioned perpendicular to the bonded interface into 1-mm-thick slices. Each specimen was trimmed with a diamond bur to an hourglass shape with a cross-sectional area of approximately 1.0 mm(2) at the bonded area. Specimens were tested (μTBS) at 0.5 mm/min using a universal testing machine. Scanning electron microscopy was used to examine the effects of prophylaxis techniques on dentin. Bond strength data (MPa) were analyzed by one-way analysis of variance and failure mode by Fisher test (α=0.05). μTBS data, means (SD), were (different superscripted letters indicate statistically significant differences): AirA, 25.2 (7.2)(a); PumP, 24.1 (7.8)(a); Chlo, 21.5 (5.6)(a); Cont, 20.6 (8.1)(a); HydP(,) 15.5 (7.6)(b); and SodB(,) 11.5 (4.4)(c). The use of aluminum oxide air abrasion, pumice paste, and chlorhexidine before acid etching did not significantly affect μTBS to dentin; however, the use of hydrogen peroxide and sodium bicarbonate jet significantly reduced μTBS.

  17. Energy intake and diet selection during buffet consumption in women classified by the 6-n-propylthiouracil bitter taste phenotype.

    PubMed

    Shafaie, Yasmine; Koelliker, Yvonne; Hoffman, Daniel J; Tepper, Beverly J

    2013-12-01

    Exposure to a variety of energy-dense foods promotes increased energy intake and adiposity. Taste blindness to the bitterness of 6-n-propylthiouracil (PROP) has been associated with increased adiposity in women and might be linked to an increased energy intake and greater selection of dietary fat. We investigated whether PROP nontaster (NT) women would consume more fat and energy in a buffet setting than medium taster (MT) or supertaster (ST) women. Seventy-five non-diet-restrained, lean, young women [mean ± SEM BMI (in kg/m²): 21.5 ± 0.6; age: 26.1 ± 1.3 y) ate lunch and dinner in the laboratory for 3 consecutive days under the following 2 conditions: ad libitum control meals (CONTs) or high-variety buffet meals (BUFFs). A standard breakfast was consumed each day of the study (4 - d washout between conditions). NTs and MTs consumed more energy and fat (as the percentage of energy) from BUFFs than did STs (P < 0.01), which contributed to higher daily energy intakes in these 2 groups of women during BUFFs (2149 ± 49 kcal/d for NTs and 2209 ± 48 kcal/d for MTs compared with 1933 ± 50 kcal/d for STs; P < 0.01). Together, NTs and MTs consumed an extra 246 kcal/d during BUFFs than during CONTs. In addition, compared with STs, NTs and MTs consumed more added fats and sweets (servings/d; P < 0.003) and more energy from snacks (P < 0.01) across all study days. NT and MT women consume more daily energy than do ST women when eating in a buffet setting, which is a common type of dietary exposure. This increase in energy intake over time could contribute to a positive energy balance and increased adiposity previously reported in these women.

  18. Intermittent cardiac overload results in adaptive hypertrophy and provides protection against left ventricular acute pressure overload insult.

    PubMed

    Moreira-Gonçalves, Daniel; Henriques-Coelho, Tiago; Fonseca, Hélder; Ferreira, Rita; Padrão, Ana Isabel; Santa, Cátia; Vieira, Sara; Silva, Ana Filipa; Amado, Francisco; Leite-Moreira, Adelino; Duarte, José Alberto

    2015-09-01

    The present study aimed to test whether a chronic intermittent workload could induce an adaptive cardiac phenotype Chronic intermittent workload induced features of adaptive hypertrophy This was paralleled by protection against acute pressure overload insult The heart may adapt favourably to balanced demands, regardless of the nature of the stimuli. The present study aimed to test whether submitting the healthy heart to intermittent and tolerable amounts of workload, independently of its nature, could result in an adaptive cardiac phenotype. Male Wistar rats were subjected to treadmill running (Ex) (n = 20), intermittent cardiac overload with dobutamine (ITO) (2 mg kg(-1) , s.c.; n = 20) or placebo administration (Cont) (n = 20) for 5 days week(-1) for 8 weeks. Animals were then killed for histological and biochemical analysis or subjected to left ventricular haemodynamic evaluation under baseline conditions, in response to isovolumetric contractions and to sustained LV acute pressure overload (35% increase in peak systolic pressure maintained for 2 h). Baseline cardiac function was enhanced only in Ex, whereas the response to isovolumetric heartbeats was improved in both ITO and Ex. By contrast to the Cont group, in which rats developed diastolic dysfunction with sustained acute pressure overload, ITO and Ex showed increased tolerance to this stress test. Both ITO and Ex developed cardiomyocyte hypertrophy without fibrosis, no overexpression of osteopontin-1 or β-myosin heavy chain, and increased expression of sarcoplasmic reticulum Ca(2+) protein. Regarding hypertrophic pathways, ITO and Ex showed activation of the protein kinase B/mammalian target of rapamycin pathway but not calcineurin. Mitochondrial complex IV and V activities were also increased in ITO and Ex. Chronic submission to controlled intermittent cardiac overload, independently of its nature, results in an adaptive cardiac phenotype. Features of the cardiac overload, such as the duration and magnitude of the stimuli, may play a role in the development of an adaptive or maladaptive phenotype. © 2015 The Authors. The Journal of Physiology © 2015 The Physiological Society.

  19. Ecological Assessment of the Effects of Army Training Activities on a Desert Ecosystem. National Training Center, Fort Irwin, California

    DTIC Science & Technology

    1985-06-01

    predators .) Several bird species ( black - throated sparrows , LeConte’s...7.3 7.7 12.5 33 28 23 24 39 Black - throated Sparrow - Amphispiza bilineata 5.0 0.3 6.7 7.7 4.5 16 1 21 24 14 Brewer’s Sparrow - Spizella breweri 6.5 0...identified as sensitive indicators of disturbances. The absence of black - throated sparrows and LeConte’s thrashers * indicate severely degraded habitats.

  20. Revision of the new world species of Hylurgops LeConte, 1876 with the description of a new genus in the Hylastini (Coleoptera: Scolytinae) and comments on some Palearctic species

    Treesearch

    Javier E. Mercado-Velez; Jose F. Negron

    2014-01-01

    The New World species of the genus Hylurgops LeConte are revised and Hylurgops subcostulatus Mannerheim is transferred to the new genus Pachysquamus. A revised key to the tribe Hylastini which can be used for the world fauna is presented to include Pachysquamus. Our studies suggest that the Nearctic species H. knausi Swaine is a valid taxon, distinguishable from the...

  1. A Model for Grain Misalignment in Cylindrical Port Motors.

    DTIC Science & Technology

    1984-04-01

    Prof. Gary A. Flandro 1 Merrill Eng. Bldg. or MEB 3008 Salt Lake City, UT 84112 Talley Industries Attn: Michael Fling P. O. Box 849 Mesa, AZ 85201...Attn: Mr. Charles W. Beckman/MS 24 Edwards AFB, CA 93523 I- - ! DISTRIBUTION LIST (CONT) No. Copies Hercules, Inc. Attn: Gary D. Berg P. 0. Box 98...DISTRIBUTION LIST (CONT) No. Copies SEA, Incorporated Attn: Mr. Gary R. Nickerson 1 1560 Brookhollow Drive Santa Ana, CA 92705 Commander Ogden ALC/MANPA Attn

  2. In vivo Ca2+ buffering capacity and microvascular oxygen pressures following muscle contractions in diabetic rat skeletal muscles: fiber-type specific effects.

    PubMed

    Eshima, Hiroaki; Poole, David C; Kano, Yutaka

    2015-07-15

    In Type 1 diabetes, skeletal muscle resting intracellular Ca(2+) concentration ([Ca(2+)]i) homeostasis is impaired following muscle contractions. It is unclear to what degree this behavior is contingent upon fiber type and muscle oxygenation conditions. We tested the hypotheses that: 1) the rise in resting [Ca(2+)]i evident in diabetic rat slow-twitch (type I) muscle would be exacerbated in fast-twitch (type II) muscle following contraction; and 2) these elevated [Ca(2+)]i levels would relate to derangement of microvascular partial pressure of oxygen (PmvO2 ) rather than sarcoplasmic reticulum dysfunction per se. Adult male Wistar rats were divided randomly into diabetic (DIA: streptozotocin ip) and healthy (CONT) groups. Four weeks later extensor digitorum longus (EDL, predominately type II fibers) and soleus (SOL, predominately type I fibers) muscle contractions were elicited by continuous electrical stimulation (120 s, 100 Hz). Ca(2+) imaging was achieved using fura 2-AM in vivo (i.e., circulation intact). DIA increased fatigability in EDL (P < 0.05) but not SOL. In recovery, SOL [Ca(2+)]i either returned to its resting baseline within 150 s (CONT 1.00 ± 0.02 at 600 s) or was not elevated in recovery at all (DIA 1.03 ± 0.02 at 600 s, P > 0.05). In recovery, EDL CONT [Ca(2+)]i also decreased to values not different from baseline (1.06 ± 0.01, P > 0.05) at 600 s. In marked contrast, EDL DIA [Ca(2+)]i remained elevated for the entire recovery period (i.e., 1.23 ± 0.03 at 600 s, P < 0.05). The inability of [Ca(2+)]i to return to baseline in EDL DIA was not associated with any reduction of SR Ca(2+)-ATPase (SERCA) 1 or SERCA2 protein levels (both increased 30-40%, P < 0.05). However, Pmv(O2) recovery kinetics were markedly slowed in EDL such that mean Pmv(O2) was substantially depressed (CONT 27.9 ± 2.0 vs. DIA 18.4 ± 2.0 Torr, P < 0.05), and this behavior was associated with the elevated [Ca(2+)]i. In contrast, this was not the case for SOL (P > 0.05) in that neither [Ca(2+)]i nor Pmv(O2) were deranged in recovery with DIA. In conclusion, recovery of [Ca(2+)]i homeostasis is impaired in diabetic rat fast-twitch but not slow-twitch muscle in concert with reduced Pmv(O2) pressures. Copyright © 2015 the American Physiological Society.

  3. Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury

    PubMed Central

    Kim, Eun Nim; Lim, Ji Hee; Kim, Min Young; Ban, Tae Hyun; Jang, In-Ae; Yoon, Hye Eun; Park, Cheol Whee; Chang, Yoon Sik

    2018-01-01

    Background. Two important issues in the aging kidney are mitochondrial dysfunction and oxidative stress. An Nrf2 activator, resveratrol, is known to have various effects. Resveratrol may prevent inflammation and oxidative stress by activating Nrf2 and SIRT1 signaling. We examined whether resveratrol could potentially ameliorate the cellular condition, such as renal injury due to cellular oxidative stress and mitochondrial dysfunction caused by aging. Methods. Male 18-month-old C57BL/6 mice were used. Resveratrol (40 mg/kg) was administered to aged mice for 6 months. We compared histological changes, oxidative stress, and aging-related protein expression in the kidney between the resveratrol-treated group (RSV) and the control group (cont). We performed experiments using small-interfering RNAs (siRNAs) for Nrf2 and SIRT1 in cultured HK2 cells. Results. Resveratrol improved renal function, proteinuria, histological changes and inflammation in aging mice. Also, expression of Nrf2-HO-1-NOQ-1 signaling and SIRT1-AMPK-PGC-1α signaling was increased in the RSV group. Transfection with Nrf2 and SIRT1 siRNA prevented resveratrol-induced anti-oxidative effect in HK2 cells in media treated with H2O2. Conclusions. Activation of the Nrf2 and SIRT1 signaling pathways ameliorated oxidative stress and mitochondrial dysfunction. Pharmacological targeting of Nrf2 signaling molecules may reduce the pathologic changes of aging in the kidney. PMID:29326403

  4. Transfer of 45Ca and 36Cl at the blood-nerve barrier of the sciatic nerve in rats fed low or high calcium diets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wadhwani, K.C.; Murphy, V.A.; Rapoport, S.I.

    1991-04-01

    Unidirectional fluxes of 45Ca, 36Cl, and of (3H)mannitol from blood into the sciatic nerve and cerebral cortex were determined from 5- and 15-min uptakes of these tracers after an intravenous (i.v.) bolus injection in awake rats. Rats were fed diets for 8 wk, that had either a low (0.01% wt/wt), normal (0.67%), or high (3%) Ca content. Plasma (Ca) was 32% less and 11% more in rats fed low (LOCA) and high Ca diets (HICA), respectively, than in rats fed a normal Ca diet (CONT). The mean permeability-surface area product (PA) of 45Ca at the blood-nerve barrier was about eightfoldmore » higher than at the blood-brain barrier in the same animals and did not differ significantly between groups (greater than 0.05). Mean PA ratios of 45Ca/36Cl for the blood-nerve and blood-brain barriers in CONT rats, 0.52 {plus minus} 0.04 and 0.40 {plus minus} 0.02, respectively, were not significantly different from corresponding ratios in LOCA and HICA groups, and corresponded to the aqueous limiting diffusion ratio (0.45). The authors results show no evidence for concentration-dependent transport of Ca over a plasma (Ca) range of 0.8-1.4 mmol/liter at the blood-nerve barrier of the rat peripheral nerve, and suggest that Ca and Cl exchange slowly between nerve and blood via paracellular pathways.« less

  5. Populações estelares em galáxias HII

    NASA Astrophysics Data System (ADS)

    Westera, P.; Cuisinier, F.; Telles, E.; Kehrig, C.

    2003-08-01

    Analisamos o conteúdo estelar de 74 galáxias HII a partir do contínuo observado nos espectros ópticos dessas galáxias, utilizando métodos de síntese de população estelar. Descobrimos que todas as galáxias para as quais encontramos soluções contêm uma população estelar velha que domina a massa estelar, e numa maioria dessas também encontramos evidência de uma população de idade intermediaria além da geração jovem que está se formando agora. Concluímos que a formação estelar dessas galáxias se realiza em surtos individuais, Esses surtos são interrompidos por longos períodos de inatividade, com os primeiros consumindo a maior parte do gás. Sugerimos, portanto, que as galáxias HII sejam galáxias anãs normais flagradas em um período de surto.

  6. Cardiopulmonary reflex, cardiac cytokines, and nandrolone decanoate: response to resistance training in rats.

    PubMed

    Lima, Ewelyne Miranda; Nascimento, Andrews Marques; Brasil, Girlandia Alexandre; Kalil, Ieda Carneiro; Lenz, Dominik; Endringer, Denise Coutinho; Andrade, Tadeu Uggere; Bissoli, Nazaré Souza

    2015-11-01

    This study evaluated the effects of nandrolone associated with resistance training (RT) on cardiac cytokines, angiotensin-converting enzyme activity (ACEA), and the sensitivity of the Bezold-Jarisch reflex (BJR). Male Wistar rats were divided into 3 groups: CONT (received vehicle, no training); EXERC (RT: after one week of water adaptation, rats were exercised by jumping into water twice a week for 4 weeks), and ND+EXERC (received nandrolone decanoate 10 mg/kg, twice/week, i.m, associated with RT). The BJR was analysed by measuring bradycardic and hypotensive responses elicited by serotonin administration. Myocyte hypertrophy and matrix collagen deposition were determined by morphometric analysis of H&E and picrosirius red-stained samples, respectively. TNF-α and ACEA were also studied. RT promoted physiological myocyte hyrpertrophy but did not cause changes in the other parameters. The association of ND with RT increased myocyte hypertrophy, deposition of matrix type I collagen, TNF-α and ACEA; decreased IL-10, and impairment in the BJR were observed in ND+EXERC compared with CONT and EXERC. ND is associated with alterations in cardiac structure and function as a result of the development of pathological cardiac hypertrophy (cardiac cytokine imbalance, elevation of ACEA) and cardiac injury, even when combined with resistance training.

  7. Modeling water flow and nitrate dynamics in a plastic mulch vegetable cultivation system using HYDRUS-2D

    NASA Astrophysics Data System (ADS)

    Filipović, Vilim; Romić, Davor; Romić, Marija; Matijević, Lana; Mallmann, Fábio J. K.; Robinson, David A.

    2016-04-01

    Growing vegetables commercially requires intensive management and involves high irrigation demands and input of agrochemicals. Plastic mulch application in combination with drip irrigation is a common agricultural management technique practiced due to variety of benefits to the crop, mostly vegetable biomass production. However, the use of these techniques can result in various impacts on water and nutrient distribution in underlying soil and consequently affect nutrient leaching towards groundwater resources. The aim of this work is to estimate the effect of plastic mulch cover in combination with drip irrigation on water and nitrate dynamics in soil using HYDRUS-2D model. The field site was located in Croatian costal karst area on a Gleysol (WRB). The experiment was designed according to the split-plot design in three repetitions and was divided into plots with plastic mulch cover (MULCH) and control plots with bare soil (CONT). Each of these plots received applications of three levels of nitrogen fertilizer: 70, 140, and 210 kg per ha. All plots were equipped with drip irrigation and cropped with bell pepper (Capsicum annuum L. cv. Bianca F1). Lysimeters were installed at 90 cm depth in all plots and were used for monitoring the water and nitrate outflow. HYDRUS-2D was used for modeling the water and nitrogen outflow in the MULCH and CONT plots, implementing the proper boundary conditions. HYDRUS-2D simulated results showed good fitting to the field site observed data in both cumulative water and nitrate outflow, with high level of agreement. Water flow simulations produced model efficiency of 0.84 for CONT and 0.56 for MULCH plots, while nitrate simulations showed model efficiency ranging from 0.67 to 0.83 and from 0.70 to 0.93, respectively. Additional simulations were performed with the absence of the lysimeter, revealing faster transport of nitrates below drip line in the CONT plots, mostly because of the increased surface area subjected to precipitation/irrigation due the absence of soil cover. Contrary, in the MULCH plots most of the nitrate applied was still left in the upper soil layer at the end of simulations. Numerical modeling revealed a large influence of plastic mulch cover on water and nutrient outflow and distribution in soil. Results suggest that under this management practice the nitrogen amounts applied via fertigation can be lowered and optimized (higher application frequencies) to reduce possible negative influence of the nitrogen based fertilizer such as leaching of nitrates to groundwater. Keywords: Plastic mulch cover; Vegetable cultivation; Water flow; Nitrate dynamics; HYDRUS-2D

  8. Effect of in ovo feeding of dextrin-iodinated casein in broilers: II. Hatch window and growth performance.

    PubMed

    Abousaad, S; Lassiter, K; Piekarski, A; Chary, P; Striplin, K; Christensen, K; Bielke, L R; Hargis, B M; Dridi, S; Bottje, W G

    2017-05-01

    Studies were conducted using a commercial InovojectTM system to determine effects of in ovo feeding of dextrin and iodinated casein (IC) on hatch and posthatch growth in broilers. At ∼18.5 d embryonic development, eggs were treated with 0, 240, or 480 μg IC/mL in saline (Cont, IC240, and IC480) or dextrin (Dext, DextIC240 and DextIC480). The Dext solution consisted of 18% maltodextrin and 10% potato starch dextrin; saline was the vehicle used by the company for in ovo vaccination. The volume for all in ovo treatments was 50 μL/injection. Eggs in Experiment 1 were transferred to a commercial hatcher unit whereas eggs in Experiments 2 and 3 were transferred to a research hatcher unit to assess effects of treatments on timing of hatch. At hatch, chicks were randomly selected and placed in floor pens and grown to 6 wk. In Experiment 1, there were no differences in hatch weights, but broilers provided Dext IC240 in ovo were heavier (P < 0.05) at 6 wk compared to other treatments with the exception of the Dext IC240 group. In Experiment 2, hatch weights were heavier (P < 0.05) in chicks receiving IC240 and DexIC480 treatments compared to Controls. At 6 wk, broilers in all treatments were heavier (P < 0.05) than Cont with the exception of IC480. In Experiment 3, hatch was stimulated by IC240 (in saline), but was delayed by Dext IC240. Serum analysis of β-hydroxybutyrate (μM/mL), as an indicator of ketone accumulation from fat metabolism of chicks held in chick boxes for 24 h posthatch (to simulate delay in placement after hatch), indicated that chicks in the IC240 group (that hatched earlier) had higher blood ketones compared to chicks that received Dext or DextIC240 in ovo (that hatched later). We conclude dextrin and iodinated casein (240 μg/mL) provided in ovo (∼18.5 d of embryonic development) has the potential to improve chick quality and posthatch body weight by delaying or narrowing hatch window. © 2016 Poultry Science Association Inc.

  9. New Staphylinidae (Coleoptera) records with new collection data from New Brunswick, Canada: Oxyporinae

    PubMed Central

    Webster, Reginald P.; DeMerchant, Ian

    2012-01-01

    Abstract Five species of Oxyporinae: Oxyporus occipitalis Fauvel, Oxyporus quinquemaculatus LeConte, Oxyporus major Gravenhorst, Oxyporus rufipennis LeConte, and Oxyporus stygicus Say, are newly recorded from New Brunswick, bringing the number of Oxyporinae known from the province to eight. The first documented records from New Brunswick are provided for Oxyporus kiteleyi reported by Majka et al. (2011). Oxyporus occipitalis and Oxyporus major are newly reported for the Maritime provinces of Canada. Collection and habitat data are presented for all these species. PMID:22577323

  10. Economic Impact Forecast System (EIFS) II: User’s Manual. Updated Edition.

    DTIC Science & Technology

    1984-05-01

    vermillion, in utica ny bea 18167 viga, in bOO bea 36011 cayuga. ny texarkana tx boa 36023 cortland, ny texarkana bea 36033 franklin, ny b119 bea...f1 48343 morris, tx 167 *.1• ’ texarkana tx boa (cont) tulsa ok boa (cont) 48387 red river, tx 40117 pawn*@, ok 48449 titus, tx 40119 payne, ok 40131...smsa texarkana ar smsa s7920 smsa texarkana tx smsa 29043 christian, ma texarkana sinsa 29077 green&, ma s8360 smsa 05081 little river, ar springfield

  11. A Study of the Magnetic and Metallurgical Properties of Sm(Co,Fe,Cu,Zr) z Alloys with z = 8.5.

    DTIC Science & Technology

    1981-01-28

    CY NAME A DORESS0it dIIG.’t from, Cont~rolling Of4’lc%) !5. SECURITY CLASS. fof this report) 3 Unclassi fled LEVEL SCHEDULE 16. DISTRIBUTION STATE14ENT... SECURITY CLASSIFICATION OF THIS PAGE(~Whe Does Entered) 16993. 1 -MS F20. AB3TBACT CO,)TINUEl Jcommerical laboratories in Japan reported that by adding...properties, before the sub- microscopic structure studies that seem to be needed for a true understanding make any sense . Similarly, it was necessary tc

  12. Corrosion-Control (CC) Program SIMA (Shore Intermediate Maintenance Activity) Pilot CC (Corrosion-Control) Shop Service Test and Technical Support. Volume 1. Final Report. Sections 1 to 8.

    DTIC Science & Technology

    1985-11-30

    fri 11 41 CC -j L ii La u 6: Kl9 L : 1 V)VI Go L...COPELAND) were conducted and 211 items were inspected. Of those degraded items, 64 required rework . Lessons learned from the inspections are proving...8217,," " "-" " ".’...’ " "-’,’-’** .* ". " -.- ".’’-"-*"-.-- " "- -" "- .. ’ ."’. . . ". ".".".. .. . . ." "’ "" .""""-"","" * r DISTRIBUTION (Cont’d) NO. OF COPES Commanding Officer, USS

  13. Effects of supportive telephone counseling in the metabolic control of elderly people with diabetes mellitus.

    PubMed

    Becker, Tânia Alves Canata; Teixeira, Carla Regina de Souza; Zanetti, Maria Lúcia; Pace, Ana Emília; Almeida, Fábio Araújo; Torquato, Maria Teresa da Costa Gonçalves

    2017-01-01

    the purpose of this study was to evaluate the efficacy of telephone-based support for the metabolic control of elderly patients with diabetes mellitus. a pragmatic study was conducted in two groups, called G1 (n=36) and G2 (n=27), at a health unit from the countryside of São Paulo state. Patients in G1 group received telephone support over four months, through 16 telephone contacts with educational material; for the G2 group the educational material was mailed. significant differences were found. The G1 group showed a reduction of the parameters of fasting glucose, as well as systolic and diastolic blood pressure. In G2 group a modest reduction was noted in some parameters, with no significant difference. telephone support was effective to deliver patient education to the diabetic elderly, leading to the reduction of fasting blood glucose. This, combined with other strategies, can contribute to reduce glycated hemoglobin (NCT 01972412). avaliar a efetividade do suporte telefônico no controle metabólico de idosos com diabetes mellitus. estudo pragmático com 63 participantes, alocados em dois grupos, denominados G1(n=36) e G2(n=27), em uma unidade de saúde do interior paulista. O suporte telefônico foi oferecido, durante quatro meses, para o G1, por meio de 16 ligações telefônicas com conteúdo educativo, e, para o G2, foram enviadas correspondências por via postal. no G1 houve significância estatística na redução dos parâmetros das variáveis glicemia de jejum, pressão arterial sistólica e diastólica. No G2, houve redução discreta de algumas variáveis, mas sem significância estatística. o suporte telefônico foi considerado uma estratégia educativa efetiva para idosos com diabetes mellitus e favoreceu a redução da glicemia de jejum e, em conjunto com outras estratégias, pode agregar valor na redução da hemoglobina glicada (NCT 01972412).

  14. Effects of clay after an aflatoxin challenge on aflatoxin clearance, milk production, and metabolism of Holstein cows.

    PubMed

    Sulzberger, S A; Melnichenko, S; Cardoso, F C

    2017-03-01

    Oral supplementation of clay to dairy cattle has been reported to reduce toxicity of aflatoxin (AF) in contaminated feed. The objective of this study was to determine the effects of 3 concentrations of dietary clay supplementation in response to an AF challenge. Ten multiparous rumen-cannulated Holstein cows [body weight (mean ± SD) = 669 ± 20 kg and 146 ± 69 d in milk], were assigned to 1 of 5 treatments in a randomized replicated 5 × 5 Latin square design balanced to measure carryover effects. Periods (21 d) were divided in an adaptation phase (d 1 to 14) and a measurement phase (d 15 to 21). From d 15 to 17, cows received an AF challenge. The challenge consisted of 100 μg of aflatoxin B 1 (AFB 1 )/kg of dietary dry matter intake (DMI). The material was fitted into 10-mL gelatin capsules and administered into the rumen through a rumen-cannula based on the average DMI obtained on d 12 to 14. Treatments were no clay plus an AF challenge (POS); 3 different concentrations of clay (0.5, 1, or 2% of dietary DMI) plus an AF challenge; and a control consisting of no clay and no AF challenge (C). Statistical analysis was performed using the MIXED procedure of SAS (SAS Institute Inc., Cary, NC). Two contrasts, CONT1 (POS vs. C) and CONT2 (POS vs. the average of 0.5, 1, and 2% clay), were compared along with the linear and quadratic treatment effects (POS, 0.5%, 1%, 2%). Cows supplemented with clay had lower AF excretion in milk as aflatoxin M 1 (AFM 1 ; 0.5% = 20.83 μg/d, 1% = 22.82 μg/d, and 2% = 16.51 μg/d) and AF transfer from rumen fluid to milk (AFM 1; 0.5% = 1.01%, 1% = 0.98%, and 2% = 0.74%) compared with cows in POS (AFM 1 = 27.81 μg/d and AF transfer = 1.37%, CONT2). Similarly, concentrations of AFM 1 in milk (0.5% = 0.35 μg/kg, 1% = 0.30 μg/kg, 2% = 0.25 μg/kg), AFB 1 in feces (0.5% = 1.79 μg/g, 1% = 1.52 μg/kg, 2% = 1.48 μg/kg), and AFB 1 in rumen fluid (0.5% = 0.05 μg/kg, 1% = 0.02 μg/kg, 2% = 0.02 μg/kg) were reduced in cows fed clay compared with POS (0.43 μg/kg, 2.78 μg/kg, and 0.10 μg/kg, respectively, CONT2). Cows supplemented with clay tended to have lower 3.5% fat-corrected milk [0.5% = 38.2 kg, 1% = 39.3 kg, 2% = 38.4 kg, standard error of the mean (SEM) = 1.8] than cows in POS (41.3 kg; SEM = 1.8; CONT2). Plasma superoxide dismutase (SOD) concentration tended to be lower for cows fed clay in the diet (0.5% = 2.16 U/mL, 1% = 1.90 U/mL, 2% = 2.3 U/mL; SEM = 0.3) than for cows in POS (2.72 U/mL; CONT2). Additionally, when cows were exposed to AF without clay in the diet, plasma concentrations of aspartate aminotransferase (AST) decreased from 84.23 (C) to 79.17 (POS) and glutamate dehydrogenase (GLDH) decreased from 91.02 (C) to 75.81 (POS). In conclusion, oral supplementation of clay reduced the transfer of AF from the rumen to milk and feces. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  15. Modified lingguizhugan decoction incorporated with dietary restriction and exercise ameliorates hyperglycemia, hyperlipidemia and hypertension in a rat model of the metabolic syndrome.

    PubMed

    Yao, Limei; Wei, Jingjing; Shi, Si; Guo, Kunbin; Wang, Xiangyu; Wang, Qi; Chen, Dingsheng; Li, Weirong

    2017-02-28

    Modified Lingguizhugan Decoction (MLD) came from famous Chinese medicine Linggui Zhugan Decoction. The MLD is used for the treatment of metabolic syndrome in the clinical setting. Our study focuses on the comprehensive treatment of MLD incorporated with dietary restriction and exercise in a rat model of the metabolic syndrome (MS). Rats were divided into five groups: control group (Cont), high-fat diet group (HFD), high-fat diet incorporated with dietary restriction group (HFD-DR), exercise incorporated with dietary restriction group (HFD-DR-Ex) and MLD incorporated with dietary restriction and exercise group (HFD-DR-Ex-MLD). Treatments were conducted for 1 week after feeding high-fat diet for 12 weeks. The effects of treatments on high fat diet-induced obesity, hyperglycemia, hyperlipidemia, hypertension, hepatic injury and insulin resistance in rats of MS were examined. In addition, the tumor necrosis factor-α (TNF-α), leptin and protein kinase B (PKB) in rats serum and liver were also examined by enzyme-linked immunosorbent assay (ELISA). After a week's intervention by dietary restriction, dietary restriction incorporated with exercise or MLD, compared with HFD rats, the relative weight of liver and fat, levels of triglyceride, total cholesterol, low-density lipoprotein, free fatty acid, aspartate aminotransferase, glutamic-pyruvic transaminase and alkaline phosphatase, insulin, were significantly decreased (p < 0.05 or 0.01). This treatment also inhibited abnormal increases of TNF-α, leptin and PKB in serum and liver. MLD incorporated with dietary restriction and exercise treatment exhibit effects in alleviating high-fat diet-induced obesity, hyperglycemia, hyperlipidemia, hypertension, hepatic injury and insulin resistance, which are possibly due to the down-regulation of TNF-α, leptin and PKB.

  16. ContEst16S: an algorithm that identifies contaminated prokaryotic genomes using 16S RNA gene sequences.

    PubMed

    Lee, Imchang; Chalita, Mauricio; Ha, Sung-Min; Na, Seong-In; Yoon, Seok-Hwan; Chun, Jongsik

    2017-06-01

    Thanks to the recent advancement of DNA sequencing technology, the cost and time of prokaryotic genome sequencing have been dramatically decreased. It has repeatedly been reported that genome sequencing using high-throughput next-generation sequencing is prone to contaminations due to its high depth of sequencing coverage. Although a few bioinformatics tools are available to detect potential contaminations, these have inherited limitations as they only use protein-coding genes. Here we introduce a new algorithm, called ContEst16S, to detect potential contaminations using 16S rRNA genes from genome assemblies. We screened 69 745 prokaryotic genomes from the NCBI Assembly Database using ContEst16S and found that 594 were contaminated by bacteria, human and plants. Of the predicted contaminated genomes, 8 % were not predicted by the existing protein-coding gene-based tool, implying that both methods can be complementary in the detection of contaminations. A web-based service of the algorithm is available at www.ezbiocloud.net/tools/contest16s.

  17. Energy substrate utilization with and without exogenous carbohydrate intake in boys and men exercising in the heat.

    PubMed

    Leites, Gabriela T; Cunha, Giovani S; Chu, Lisa; Meyer, Flavia; Timmons, Brian W

    2016-11-01

    Little is known about energy yield during exercise in the heat in boys compared with men. To investigate substrate utilization with and without exogenous carbohydrate (CHO exo ) intake, seven boys [11.2 ± 0.2 (SE) yr] and nine men (24.0 ± 1.1 yr) cycled (4 × 20-min bouts) at a fixed metabolic heat production (Ḣ p ) per unit body mass (6 W/kg) in a climate chamber (38°C and 50% relative humidity), on two occasions. Participants consumed a 13 C-enriched 8% CHO beverage (CARB) or placebo beverage (CONT) in a double-blinded, counterbalanced manner. Substrate utilization was calculated for the last 60 min of exercise. CHO exo oxidation rate (2.0 ± 0.3 vs. 2.5 ± 0.2 mg·kg fat-free mass -1 ·min -1 , P = 0.02) and CHO exo oxidation efficiency (12.8 ± 0.6 vs. 16.0 ± 0.9%, P = 0.01) were lower in boys compared with men exercising in the heat. Total carbohydrate (CHO total ), endogenous CHO (CHO endo ), and total fat (Fat total ) remained stable in boys and men (P > 0.05) during CARB, whereas CHO total oxidation rate decreased (P < 0.001) and Fat total oxidation rate increased over time similarly in boys and men during CONT (P < 0.001). The relative contribution of CHO exo to total energy yield increased over time in both groups (P < 0.001). In conclusion, endogenous substrate metabolism and the relative contribution of fuels to total energy yield were not different between groups. The ingestion of a CHO beverage during exercise in the heat may be as beneficial for boys as men to spare endogenous substrate. Copyright © 2016 the American Physiological Society.

  18. Cognitive and physiological dissociations in response to emotional pictures in patients with anorexia.

    PubMed

    Nandrino, Jean-Louis; Berna, Guillaume; Hot, Pascal; Dodin, Vincent; Latrée, Julie; Decharles, Sandra; Sequeira, Henrique

    2012-01-01

    Recent studies suggest that patients with anorexia may express dissociated cognitive and physiological reactivities to emotional stimuli. The present research aimed to compare subjective and autonomic responses to pleasant, unpleasant and neutral scenes during a categorization task and an activation rating task in anorexic (AN), alexithymic (AL), depressed (DEP) and control participants (CONT). The participants first categorized pictures according to their emotional valence, followed by a rating of their activation level, concomitant with the recording of skin conductance responses (SCRs). Main findings showed that the AN patients presented major difficulty in categorizing pictures, particularly neutral ones. Contrary to the AL participants, this difficulty did not induce significant increases of SCR amplitude in the AN patients. In the second task, the AN patients rated the intensity of activation of unpleasant pictures higher than the AL participants and that of pleasant ones higher than the AL and CONT participants. In addition, no significant linear correlation was observed between the intensity of activation ratings and SCR amplitude in the AN, AL or DEP participants contrarily to what was observed for control participants. This lack of relation suggests a non-specific disconnection between physiological and cognitive self-reported responses to emotional stimuli. Our results highlight a specific form of emotional processing in the AN patients distinct from that observed in alexithymia or depression and characterized by a dissociation between cognitive and physiological responses. This kind of disconnection could be associated with emotional regulation processes and may benefit the AN patients by lowering the psychological stress response. Copyright © 2011 Elsevier Inc. All rights reserved.

  19. A Model for Determining Task Set Schedulability in the Presence of System Effects

    DTIC Science & Technology

    1992-12-01

    A-34 A.20.100ps data (cont) .............................................. A- 35 A.21.100ps data (cont...Specification Item [ Range User Tasks 0 to 99 System Tasks no limit Simulation Time (in ps) 0 to 2,100,000,000 (0 to 35 minutes) Synchronization Events...3.800* 32 363.4 57 332.3 82 310.1 8 3.800* 33 352.6 58 332.5 83 307.9 9 3.800* 34 359.3 59 330.1 84 314.3 10 3.800* 35 353.3 60 324.8 85 304.6 11 3.800

  20. Image analysis to evaluate the browning degree of banana (Musa spp.) peel.

    PubMed

    Cho, Jeong-Seok; Lee, Hyeon-Jeong; Park, Jung-Hoon; Sung, Jun-Hyung; Choi, Ji-Young; Moon, Kwang-Deog

    2016-03-01

    Image analysis was applied to examine banana peel browning. The banana samples were divided into 3 treatment groups: no treatment and normal packaging (Cont); CO2 gas exchange packaging (CO); normal packaging with an ethylene generator (ET). We confirmed that the browning of banana peels developed more quickly in the CO group than the other groups based on sensory test and enzyme assay. The G (green) and CIE L(∗), a(∗), and b(∗) values obtained from the image analysis sharply increased or decreased in the CO group. And these colour values showed high correlation coefficients (>0.9) with the sensory test results. CIE L(∗)a(∗)b(∗) values using a colorimeter also showed high correlation coefficients but comparatively lower than those of image analysis. Based on this analysis, browning of the banana occurred more quickly for CO2 gas exchange packaging, and image analysis can be used to evaluate the browning of banana peels. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Evaluating glacier movement fluctuations using remote sensing: A case study of the Baird, Patterson, LeConte, and Shakes glaciers in central Southeastern Alaska

    NASA Astrophysics Data System (ADS)

    Davidson, Robert Howard

    Global Land Survey (GLS) data encompassing Landsat Multispectral Scanner (MSS), Landsat 5's Thematic Mapper (TM), and Landsat 7's Enhanced Thematic Mapper Plus (ETM+) were used to determine the terminus locations of Baird, Patterson, LeConte, and Shakes Glaciers in Alaska in the time period 1975-2010. The sequences of the terminuses locations were investigated to determine the movement rates of these glaciers with respect to specific physical and environmental conditions. GLS data from 1975, 1990, 2000, 2005, and 2010 in false-color composite images enhancing ice-snow differentiation and Iterative Self-Organizing (ISO) Data Cluster Unsupervised Classifications were used to 1) quantify the movement rates of Baird, Patterson, LeConte, and Shakes Glaciers; 2) analyze the movement rates for glaciers with similar terminal terrain conditions and; 3) analyze the movement rates for glaciers with dissimilar terminal terrain conditions. From the established sequence of terminus locations, movement distances were quantified between the glacier locations. Movement distances were then compared to see if any correlation existed between glaciers with similar or dissimilar terminal terrain conditions. The Global Land Ice Measurement from Space (GLIMS) data was used as a starting point from which glacier movement was measured for Baird, Patterson, and LeConte Glaciers only as the Shakes Glacier is currently not included in the GLIMS database. The National Oceanographic and Atmospheric Administration (NOAA) temperature data collected at the Petersburg, Alaska, meteorological station (from January 1, 1973 to December 31, 2009) were used to help in the understanding of the climatic condition in this area and potential impact on glaciers terminus. Results show that glaciers with similar terminal terrain conditions (Patterson and Shakes Glaciers) and glaciers with dissimilar terminal terrain conditions (Baird, Patterson, and LeConte Glaciers) did not exhibit similar movement rates. Glacier movement rates were greatest for glaciers whose terminuses were in fresh water (Patterson and Shakes Glaciers), less for those with terminuses in salt water (LeConte Glacier), and least for glaciers with terminuses on dry land (Baird Glacier).Based upon these findings, the presence of water, especially fresh water, at the terminal end of the Patterson and Shakes Glaciers had a greater effect on glacier movement than slope. Possible explanations for this effect might include a heat sink effect or tidal motions that hasten glacier disintegration in the ablation zone. In a heat sink scenario, the water bodies in which the Patterson and Shakes Glaciers terminus are located could act as a thermal energy transfer medium that increases glacier melting and subsequent retreat. On the other hand, tidal motions could act as horizontal and vertical push/pull forces, which increase the fracturing rate, calving, and subsequent retreat of glaciers terminus that are is salt water like the LeConte Glacier. Over the length of the study period, 1975 through 2010, there has been a 0.85°C increase in annual air temperatures that, although may seem low, may prove important when determining glacial mass balance rates. Further studies are necessary to test these hypotheses to determine if a heat sink effect and tidal motions significantly affected the movement rates for the glaciers in this study area. An additional significant result of this study was the creation of shapefiles delineating the positions of the Shakes Glaciers that are being submitted to the Global Land Ice Measurements from Space (GLIMS) program for inclusion in their master worldwide glacier database.

  2. Motor Timing Deficits in Sequential Movements in Parkinson Disease Are Related to Action Planning: A Motor Imagery Study

    PubMed Central

    Avanzino, Laura; Pelosin, Elisa; Martino, Davide; Abbruzzese, Giovanni

    2013-01-01

    Timing of sequential movements is altered in Parkinson disease (PD). Whether timing deficits in internally generated sequential movements in PD depends also on difficulties in motor planning, rather than merely on a defective ability to materially perform the planned movement is still undefined. To unveil this issue, we adopted a modified version of an established test for motor timing, i.e. the synchronization–continuation paradigm, by introducing a motor imagery task. Motor imagery is thought to involve mainly processes of movement preparation, with reduced involvement of end-stage movement execution-related processes. Fourteen patients with PD and twelve matched healthy volunteers were asked to tap in synchrony with a metronome cue (SYNC) and then, when the tone stopped, to keep tapping, trying to maintain the same rhythm (CONT-EXE) or to imagine tapping at the same rhythm, rather than actually performing it (CONT-MI). We tested both a sub-second and a supra-second inter-stimulus interval between the cues. Performance was recorded using a sensor-engineered glove and analyzed measuring the temporal error and the interval reproduction accuracy index. PD patients were less accurate than healthy subjects in the supra-second time reproduction task when performing both continuation tasks (CONT-MI and CONT-EXE), whereas no difference was detected in the synchronization task and on all tasks involving a sub-second interval. Our findings suggest that PD patients exhibit a selective deficit in motor timing for sequential movements that are separated by a supra-second interval and that this deficit may be explained by a defect of motor planning. Further, we propose that difficulties in motor planning are of a sufficient degree of severity in PD to affect also the motor performance in the supra-second time reproduction task. PMID:24086534

  3. A Utilização da Astronomia como Tema Interdisciplinar e Aplicações de Objetos de Aprendizagem

    NASA Astrophysics Data System (ADS)

    da Silva, L. A.; Voelzke, M. R.

    2008-09-01

    Este trabalho visa analisar a possibilidade de relacionar conteúdos aplicados no ensino fundamental e médio de forma interdisciplinar por intermédio da astronomia, com a intervenção de objetos de aprendizagem que possam integrar as disciplinas e a utilização de recursos tecnológicos. Em uma pesquisa prévia com 20 professores de uma escola estadual situada na cidade de Guarulhos foi observado que apenas 25% dos professores utilizam algum recurso tecnológico para o desenvolvimento de conteúdos pertinentes à sua disciplina, tais como sites e softwares educativos, sendo que a maioria absoluta continua ensinando apenas com livros didáticos. A maior parte dos professores apresenta dificuldades em trabalhar sua disciplina de forma interdisciplinar, ou seja, 75% dos professores preferem aplicar os conteúdos seguindo uma hierarquia linear de tópicos, evitando a discussão de temas que de alguma forma estão relacionados. A astronomia pode vir à fascinar o ser humano e despertar sua curiosidade promovendo um maior interesse no aprendizado, podendo favorecer análises interdisciplinares de forma lógica e objetiva, desta forma colocar a astronomia como tema motivador interdisciplinar, pode ser relevante no que se refere ao distanciamento da fragmentação dos conteúdos. No Estado de São Paulo, a implantação da proposta curricular no ensino fundamental e médio mostra claramente a inserção da astronomia na maior parte das séries, principalmente na 6ª série em que todo o bimestre se fala de astronomia.

  4. Pulmonary gas exchange efficiency during exercise breathing normoxic and hypoxic gas in adults born very preterm with low diffusion capacity.

    PubMed

    Duke, Joseph W; Elliott, Jonathan E; Laurie, Steven S; Beasley, Kara M; Mangum, Tyler S; Hawn, Jerold A; Gladstone, Igor M; Lovering, Andrew T

    2014-09-01

    Adults with a history of very preterm birth (<32 wk gestational age; PRET) have reduced lung function and significantly lower lung diffusion capacity for carbon monoxide (DLCO) relative to individuals born at term (CONT). Low DLCO may predispose PRET to diffusion limitation during exercise, particularly while breathing hypoxic gas because of a reduced O2 driving gradient and pulmonary capillary transit time. We hypothesized that PRET would have significantly worse pulmonary gas exchange efficiency [i.e., increased alveolar-to-arterial Po2 difference (AaDO2)] during exercise breathing room air or hypoxic gas (FiO2 = 0.12) compared with CONT. To test this hypothesis, we compared the AaDO2 in PRET (n = 13) with a clinically mild reduction in DLCO (72 ± 7% of predicted) and CONT (n = 14) with normal DLCO (105 ± 10% of predicted) pre- and during exercise breathing room air and hypoxic gas. Measurements of temperature-corrected arterial blood gases, and direct measure of O2 saturation (SaO2), were made prior to and during exercise at 25, 50, and 75% of peak oxygen consumption (V̇o2peak) while breathing room air and hypoxic gas. In addition to DLCO, pulmonary function and exercise capacity were significantly less in PRET. Despite PRET having low DLCO, no differences were observed in the AaDO2 or SaO2 pre- or during exercise breathing room air or hypoxic gas compared with CONT. Although our findings were unexpected, we conclude that reduced pulmonary function and low DLCO resulting from very preterm birth does not cause a measureable reduction in pulmonary gas exchange efficiency. Copyright © 2014 the American Physiological Society.

  5. The Role of Affect in Cross-Cultural Competence

    DTIC Science & Technology

    2012-04-26

    4.56 2.58 .70 .89 Food Affect (pre) 1.00 5.00 3.10 .70 .91 Food Affect (post) 1.00 5.00 3.22 1.00 .95 Food Safety (pre) 1.57 5.00 3.35 .82 Food ...controlled for  Looked at affect in terms of food affect and food safety Hypotheses and Results (cont.) • Hypothesis 2a*: Disgust sensitivity will be...05 • Food Safety , r(96)=-.13, n.s. • Disgust Sensitivity, r(96)=-.16, n.s. • Contamination, r(96)=-.24, p<.05 • Core Disgust, r(96)=-.20, p=.05

  6. Environmental Considerations and Sustainability of Base Camps in Contingency Operations

    DTIC Science & Technology

    2011-05-12

    for failing to comply with a collection of information if it does not display a currently valid OMB control number. 1. REPORT DATE 12 MAY 2011 2 ...Seaottlllll-leo~ prDJtOnonli!X bliSo CIIIJI!N. 2 . Tho """v dlltt n ot havo on ...... stnt•gy to ellblllloh, ....aoln . oAd tnnllill011 14on...Major ObJecUve 2 ·10 ŕnstltutlonollzeContJngenct B1S1ng" lnlegroted Un II. Bua and lnstablion P1 otecbon (IU IB P) IC DT Army Enttg:f Stcuuty

  7. Long-term simulations of water and isoproturon dynamics in a heterogeneous soil receiving different urban waste composts

    NASA Astrophysics Data System (ADS)

    Filipović, Vilim; Coquet, Yves; Pot, Valérie; Romić, Davor; Benoit, Pierre; Houot, Sabine

    2016-04-01

    Implementing various compost amendments and tillage practices has a large influence on soil structure and can create heterogeneities at the plot/field scale. While tillage affects soil physical properties, compost application influences also chemical properties like pesticide sorption and degradation. A long-term field experiment called "QualiAgro" (https://www6.inra.fr/qualiagro_eng/), conducted since 1998 aims at characterizing the agronomic value of urban waste composts and their environmental impacts. A modeling study was carried out using HYDRUS-2D for the 2004-2010 period to confront the effects of two different compost types combined with the presence of heterogeneities due to tillage in terms of water and isoproturon dynamics in soil. A municipal solid waste compost (MSW) and a co-compost of sewage sludge and green wastes (SGW) have been applied to experimental plots and compared to a control plot without any compost addition (CONT). Two wick lysimeters, 5 TDR probes, and 7 tensiometers were installed per plot to monitor water and isoproturon dynamics. In the ploughed layer, four zones with differing soil structure were identified: compacted clods (Δ), non-compacted soil (Γ), interfurrows (IF), and the plough pan (PP). These different soil structural zones were implemented into HYDRUS-2D according to field observation and using measured soil hydraulic properties. Lysimeter data showed (2004 -2010 period) that the CONT plot had the largest cumulative water outflow (1388 mm) compared to the MSW plot (962 mm) and SGW plot (979 mm). HYDRUS-2D was able to describe cumulative water outflow after calibration of soil hydraulic properties, for the whole 2004-2010 period with a model efficiency value of 0.99 for all three plots. Isoproturon leaching showed had the largest cumulative value in the CONT plot (21.31 μg) while similar cumulated isoproturon leachings were measured in the SGW (0.663 μg) and MSW (0.245 μg) plots. The model was able to simulate isoproturon leaching patterns except for the large preferential flow events that were observed in the MSW and CONT plots. The timing of these preferential flow events could be reproduced by the model but not their magnitude. Additional simulations were carried out, assuming temporal variation of the IPU degradation rate to explain the leaching events observed at the end of the monitoring period (2010). Modeling results indicate that spatial and temporal variations in pesticide degradation rate due to tillage and compost application play a major role in the dynamics of isoproturon leaching. Both types of compost were found to reduce isoproturon leaching on the long-term (6 years) duration of the field experiment. Keywords: Compost amendment; Soil heterogeneity; Conventional tillage; Water flow; Isoproturon; HYDRUS-2D

  8. New Staphylinidae (Coleoptera) records with new collection data from New Brunswick, Canada: Scaphidiinae, Piestinae, Osorinae, and Oxytelinae

    PubMed Central

    Webster, Reginald P.; Sweeney, Jon D.; DeMerchant, Ian

    2012-01-01

    Abstract Nine species of Scaphidiinae are newly reported for New Brunswick, Canada, bringing the total number of species known from the province to 12. Scaphium castanipes Kirby, Baeocera inexspectata Löbl and Stephen, Baeocera securiforma (Cornell), Scaphisoma repandum Casey, and Toxidium gammaroides LeConte are reported for the first time from the Maritime provinces. Siagonum punctatum LeConte and Siagonum stacesmithi Hatch, and the subfamily Piestinae are reported for the first time from New Brunswick. The subfamily Osoriinae is reported for the first time from New Brunswick and the Maritime provinces based on the collection of three species: Clavilispinus prolixus (LeConte), Thoracophorus costalis (Erichson), and a Lispinodes species. The Lispinodes species is also newly recorded for Canada. Six species of Oxytelinae are newly recorded from New Brunswick, bringing the total number of species of this subfamily known to the province to 20. Apocellus sphaericollis (Say) and Platystethus americanus Erichson are new to the Maritime provinces. Additional locality and bionomic data are presented for Mitosynum vockerothi Campbell, and the male genitalia are illustrated for the first time. Collection and bionomic data are presented for all included species. PMID:22577322

  9. [Theory of mind in Asperger syndrome].

    PubMed

    Duverger, H; Da Fonseca, D; Bailly, D; Deruelle, C

    2007-09-01

    Theory of mind deficit can be used to explain social and communication impairments that define the autism spectrum disorder. Theory of mind is the ability to attribute mental states to self and others in order to understand and predict behavior. It involves the distinction between the real world and mental representations of the world. Several studies established that high functioning autistic individuals and individuals with Asperger syndrome (ASP) tend to be as proficient as controls in understanding first order false belief tasks. In contrast, they still lag behind their typical peers in understanding second order false belief tasks or more advanced tasks of theory of mind (e.g., Baron-Cohen, 1993). Most of these studies focus on the adult population and it seems particularly interesting to investigate whether children with ASP would present the same pattern of strengths and deficits as adults. In our research, children with ASP were tested in an advanced task of theory of mind based on a visual presentation of comic strips and in a more traditional assessment of false belief understanding: the Smarties test. Two experimental groups participated in this study: a group of 16 high functioning children and adolescents with autism or with Asperger syndrome (ASP) and a group of 16 typically developing children matched on gender and age (CONT). The task was designed to assess the ability of children with ASP to infer the mental state of others. Stimuli were 26 different comic strips depicting a short story. Each comic strip was composed of three pictures and was shown on the upper half of the screen. Then three pictures numbered 1 to 3 showing possible outcomes of the scenario were superimposed on the bottom half of the screen. Only one of these three pictures represented a plausible conclusion to the scenario. This experiment contained two conditions: A Character intention (CI) condition and a Physical causality (PC) condition. The comic strips in the CI condition involved one character whose intentions had to be inferred by the subject in order to choose the correct picture. Comic strips in PC condition only required to understand physical causalities. Subjects were asked to watch the comic strip attentively and then they were required to make a choice between the three story endings by pressing the corresponding keyboard button. Both answers and response times were recorded. Additionally, all participants were enrolled in the classical false belief (Smarties) task. Comic strips: An ANOVA [2 groups (CONT/ASP) x 2 conditions (CI/PC)] was performed on the number of correct responses. Neither the Group nor the Condition factor was significant (p>0.05). In contrast, the interaction Group x Condition reached significance level [F(1-30)=4.3, p<0.05)]. Further analysis revealed that performance of the ASP group was significantly higher in the CP (M=10.8, SD=2.5) than in the CI (M=9.8, SD=2) condition [t (1-14)=2.9, p<0.001)], whereas there was no condition difference in the control group (p>0.05). False belief: all ASP participants succeeded in the task. Our data clearly demonstrated that children and adolescents with Asperger syndrome or high functioning autism exhibited an impairment in understanding the intention of others. In the comic strip task, children with ASP have more difficulties in the character's intention condition than in the physical causality condition. This impairment is not imputable to a deficit in taking into account the context (Weack Central Coherence theory) since they performed as well as controls in the physical causality condition which also required the processing of the whole scene. In contrast, all children with ASP succeeded at the false belief task. These contradictory findings suggest that, although testing theory of mind, the two tasks do not tap similar mechanisms. It is possible that the use of verbal material in the false belief task improved performance of the ASP children who are known to present particular strengths in this domain. Another possible explanation that needs further testing would be that the level of complexity differs between the two tasks.

  10. [Experimental study of acute brain swelling under acute intracranial hypertension (author's transl)].

    PubMed

    Shigemori, M; Watanabe, M; Kuramoto, S

    1976-12-01

    There are many problems about the cause, pathophysiology and treatment of acute brain swelling under intracranial hypertension frequently encountered in the neurosurgical clinics. Generally, rapid increase of the cerebral vasoparesis caused by unknown etiology is thought to be the main cause of acute brain swelling under intracranial hypertension. Moreover, disturbance of the cerebral venous circulatory system is discussed recently by many authors. But, research from the point of systemic respiration and hemodynamics is necessary for resolving these problems. This experiment was designed to study the effects of respiration and hemodynamics on the cerebral vasoparesis. Using 22 adult dogs, acute intracranial hypertension was produced by epidural balloon inflation sustained at the level of 300 - 400 mmH2O. Simultaneously with measurement of intracranial pressure at the epidural space, superior sagittal sinus pressure, respirogram, systemic blood pressure (femoral artery), central venous pressure, common carotid blood flow, EKG and bipolar lead EEG were monitored continuously. The experimental group was divided by the respiratory loading into 5 groups as follows: control (6 cases), 10% CO2 hypercapnia (4 cases), 10% O2 hypoxia (4 cases), stenosis of airway (5 cases), 100% O2-controled respiration (3 cases). 1) Cerebral vasoparesis under acute intracranial hypertension took place earlier and showed more rapid progression in groups of stenosis of airway, hypercapnia and hypoxia than control group of spontaneous respiration in room air. No occurrence of cerebral vasoparesis was found out in a group of 100% O2 controlled respiration. It is proved that increased airway resistance or asphyxia, hypercapnia and hypoxia have strictly reference to the occurrence and progression of cerebral vasoparesis and for the prevention of cerebral vasoparesis, correct 100% O2 cont rolled respiration is effective. 2) From the hemodynamic change, the progression of rapid increase of cerebral blood volume with increase of blood volume in the superior sagitta sinus during cerebral vasoparesis under intracranial hypertension is presumed. It is suggested from the superior sagittal sinus pressure in various experimental groups that the site, reactivity and disturbed degree of the cerebral venous system are changed by the difference of respiratory or ventrilatory state and the cerebral venous circulatory disturbance has also reference to the occurrence of acute brain swelling. 3) During cerebral vasopareris under acute intracranial hypertension, remarkable supression of respiration, increased central venous pressure and increased common carotid blood flow were observed. It is concluded that the reaction of systemic hemodynamics following respiratory change effects on cerebral circulation markedly and they are being important factors to occurrence of acute brain swelling.

  11. Modulation of CYP1A2 and CYP3A6 catalytic activities by serum from rabbits with a turpentine-induced inflammatory reaction and interleukin 6.

    PubMed

    Kourylko, Oksana; Fradette, Caroline; Arcand, Mathieu; du Souich, Patrick

    2006-01-01

    Inflammatory reactions reduce the activity of cytochrome P450 isoforms. The aim of the study was to determine the mechanisms underlying the decrease in CYP1A2 and CYP3A6 catalytic activities produced by serum from rabbits with a turpentine-induced inflammatory reaction (S(TIIR)) and interleukin 6 (IL-6). S(TIIR) and IL-6 were incubated with cultured primary hepatocytes from control rabbits (H(CONT)), and from rabbits with a turpentine-induced inflammatory reaction (H(TIIR)) in the absence or presence of pyrrolidine dithiocarbamate (PDTC), an antioxidant and inhibitor of nuclear factor kappaB transcription; 2'-amino-3'-methoxyflavone (PD98059), an inhibitor of extracellular signal-related kinase (Erk1/2); 4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole (SB203580), an inhibitor of p38MAPK; Nomega-nitro-L-arginine methyl ester, an inhibitor of nitric-oxide synthase 2 (NOS2); the combination of PDTC, PD98059, and SB203580; and genistein, an inhibitor of Janus-associated protein tyrosine kinase (JAK). After 4 and 24 h of incubation of H(CONT) with S(TIIR) and IL-6, CYP1A2 activity was reduced without changes in expression; the reduction in activity was partially prevented by the inhibition of JAK, Erk1/2, and NOS2. In H(CONT), S(TIIR) and IL-6 did not affect CYP3A6 activity; however, PDTC reduced CYP3A6 activity by 40 and 80% after 4 and 24 h of incubation. In H(TIIR), S(TIIR) and IL-6 reduced both CYP1A2 and CYP3A6 activities; this decrease is partially prevented by inhibitors of protein tyrosine kinases, Erk1/2, and NOS2. In H(TIIR), SB203580 increased CYP3A6 activity in a dose-dependent manner without changes in protein expression. These results show that the signal transduction pathways mediating the decrease in CYP1A2 and 3A6 activity, produced by S(TIIR) and IL-6, involve JAK, Erk1/2, and NOS2.

  12. Differential Effects of Intermittent versus Continuous Haloperidol Treatment throughout Adolescence on Haloperidol Sensitization and Social Behavior in Adulthood

    PubMed Central

    Gao, Jun; Li, Ming

    2014-01-01

    Animal work on the behavioral effects of antipsychotic treatment suggests that different dosing regimens could affect drug sensitivity differently, with an intermittent treatment regimen tending to cause a sensitization effect, while a continuous treatment causing a tolerance. In this study, we explored how haloperidol (HAL) sensitization induced throughout adolescence and tested in adulthood was differentially impacted by these two dosing regimens in the conditioned avoidance response (CAR) test. We also examined how these two dosing regiments affected social interaction and social memory in adulthood. Male adolescent Sprague-Dawley rats were treated with HAL via either osmotic minipump (HAL-0.25 CONT; 0.25 mg/kg/day, n = 14) or daily injection (HAL-0.05 INT; 0.05 mg/kg/injection/day, sc, n = 14), or sterile water (n = 14) from postnatal days (PND) 44 to 71. HAL sensitization was assessed in a challenge test in which all rats were injected with HAL (0.025 and 0.05 mg/kg, sc) on PND 80 and PND 82. Two days later, half of the rats from each group (n = 7/group) were assayed in two 4-trial social interaction tests in which a subject rat was given four 5-min social encounters with a familiar or novel juvenile rat (PND 35–40) at 10 min intervals. Another half were tested in a quinpirole-induced hyperlocomotion assay to assess the potential HAL-induced change in D2-mediated function. Results show that only the intermittent dosing group under the HAL 0.05 mg/kg challenge showed a robust sensitization effect as rats in this group made significantly fewer avoidance responses than those in the vehicle and HAL-0.25 CONT groups. Adolescent HAL treatment did not affect social behavior and social memory, as rats from all 3 groups exhibited a similar level of social interaction and showed a similar level of sensitivity to the change of social stimuli. Similarly, adolescent HAL treatment also did not produce a long-lasting change in D2 function, as all 3 groups exhibited a similar level of increase in motor activity under quinpirole challenge. These findings suggest that HAL sensitization is a dosing-specific phenomenon. It is more likely to be seen under an intermittent dosing regimen than under a continuous dosing one. The findings that the intermittent HAL treatment did not impair social functioning and did not alter D2 function suggest a dissociation between drug-induced alterations in drug sensitivity and those in social function and neuroreceptors. PMID:24942467

  13. Early potential effects of resveratrol supplementation on skeletal muscle adaptation involved in exercise-induced weight loss in obese mice.

    PubMed

    Sun, Jingyu; Zhang, Chen; Kim, MinJeong; Su, Yajuan; Qin, Lili; Dong, Jingmei; Zhou, Yunhe; Ding, Shuzhe

    2018-04-01

    Exercise and resveratrol supplementation exhibit anti-obesity functions in the long term but have not been fully investigated yet in terms of their early potential effectiveness. Mice fed with high-fat diet were categorized into control (Cont), exercise (Ex), resveratrol supplementation (Res), and exercise combined with resveratrol supplementation (Ex + Res) groups. In the four-week period of weight loss, exercise combined with resveratrol supplementation exerted no additional effects on body weight loss but significantly improved whole-body glucose and lipid homeostasis. The combined treatment significantly decreased intrahepatic lipid content but did not affect intramyocellular lipid content. Moreover, the treatment significantly increased the contents of mtDNA and cytochrome c, the expression levels of peroxisome proliferator-activated receptor gamma coactivator-1 alpha and its downstream transcription factors, and the activities of ATPase and citrate synthase. However, exercise, resveratrol, and their combination did not promote myofiber specification toward slow-twitch type. The effects of exercise combined with resveratrol supplementation on weight loss could be partly due to enhanced mitochondrial biogenesis and not to fiber-type shift in skeletal muscle tissues. [BMB Reports 2018; 51(4): 200-205].

  14. Installation Restoration Program. Ohio Air National Guard, Toledo Express Airport, Swanton, Ohio. Quality Assurance Project Plan, Project Health and Safety Plan

    DTIC Science & Technology

    1990-04-01

    j Client’s I.D. I Cont. I Cont. Deec . I Comments • Sample Condition 4,4~ , 4 I I a I * a a I By Tm : ReevdB:- ie By: Tm:RevdB: TieUI M ___ _. _ a...tLa* 0 0 0 0 -T 0 0 N1 f4" V-t %D C9 -t t Cri’,O~~t In! CAlr In- I n-. I - ul 0 0 w 0 w-w V al IL) ., 0-4 0w~ S -4 bO 1 r- -4 u w u GD 0. &, -4 M to 4

  15. New Staphylinidae (Coleoptera) records with new collection data from New Brunswick, Canada: Omaliinae, Micropeplinae, Phloeocharinae, Olisthaerinae, and Habrocerinae

    PubMed Central

    Webster, Reginald P.; Sweeney, Jon D.; DeMerchant, Ian

    2012-01-01

    Abstract Eleven species of Omaliinae are newly recorded from New Brunswick, bringing the total number of species known from the province to 32 described species. Supporting data are presented for the New Brunswick record of Geodromicus strictus (Fauvel) reported by Majka et al. (2011). Micropeplus browni Campbell, Micropeplus laticollis Mäklin (Micropeplinae), Charyhyphus picipennis (LeConte) (Phloeocharinae), Olisthaerus substriatus (Paykull) (Olisthaerinae), Habrocerus capillaricornis (Gravenhorst), Habrocerus magnus LeConte, and Habrocerus schwarzi Horn (Habrocerinae) are also newly recorded for New Brunswick. These are the first records of the latter four subfamilies from New Brunswick. Collection and bionomic data are presented for each species and discussed. PMID:22577316

  16. Review of the species of Paratenetus Spinola inhabiting America, north of Mexico (Coleoptera, Tenebrionidae)

    PubMed Central

    Bousquet, Yves; Bouchard, Patrice

    2014-01-01

    Abstract The North American (north of Mexico) species of the tenebrionid genus Paratenetus Spinola are reviewed and a key is presented for their identification. Five species are recognized, P. gibbipennis Motschulsky, P. fuscus LeConte, P. punctatus Spinola and two sp. n., P. exutus [type locality: Tabusintac, Nova Scotia] and P. texanus [type locality: Port Isabel, Cameron County, Texas]. Two syn. n. are proposed: P. cribratus Motschulsky, 1868 with P. gibbipennis Motschulsky, 1868 and P. crinitus Fall, 1907 with P. fuscus LeConte, 1850. A lectotype is selected for Paratenetus punctatus Spinola. A type species is designated for Storthephora Mäklin, 1875 (Storthephora denticollis Mäklin, 1875). PMID:25009423

  17. New Coleoptera records from New Brunswick, Canada: Cerambycidae.

    PubMed

    Webster, Reginald P; Sweeney, Jon D; Demerchant, Ian; Silk, Peter J; Mayo, Peter

    2012-01-01

    Five species of Cerambycidae, Acmaeops discoideus (Haldeman), Anelaphus villosus (Fabricius), Phymatodes species (CNC sp. n. #1), Sarosesthes fulminans (Fabricius), and Urgleptus signatus (LeConte) are newly recorded for New Brunswick, Canada. All but Acmaeops villosus are new to the Maritime provinces. Phymatodes testaceus (Linnaeus) is removed from the faunal list of the province as a result of mislabeled specimens, records of Phymatodes maculicollis LeConte are presented confirming the presence of this species in New Brunswick, and the first recent records ofNeospondylis upiformis (Mannerheim) are presented. Additional records are given for the recently recorded Phymatodes aereus (Newman), indicating a wider distribution in the province. Collection data, habitat data, and distribution maps are presented for each species.

  18. Department of the Air Force Justification of Estimates for Fiscal Year 1986 Submitted to Congress February 1985. Aircraft Procurement, Air Force

    DTIC Science & Technology

    1985-02-01

    air-to-grurod cruise missile planned for use c-i the bomber force. IAs one of the zany i,,eapons iu the manned tmorer’s arsenal, t.L AO’ stresses the...29.4 78.4 SPX Cuminication Replacent 8.9 - - tIL OIR PRO•XUJfIN C&X4 ES 1413.3 1877.4 2683.7 3382.3 i ," / Justification for the various line items is...COntROL SYSTEMS DJE TO THE STRESS CORROSION CRACKING TiAT DEVELOPS. THI$ MODIFICATION REPLACES ThE MAGNESIUM COMPONENTS IN THE FLIGHT CONTROL SYSTEM WITH

  19. Development of a Low Cost Molded Plastic Missile/RPV Control Surface Actuator

    DTIC Science & Technology

    1975-10-01

    Glass Fiber 3 2.1.2.2 Nylon/30% Glaso Fiber 7 2.2 Phase I Testing Of Polyimide/Glass 8 j/ Burst Testsl 11tig 2.2.2atgu TechShatset S.2. Phse Cliner oldng...Dimensional and Hard- 23 a >~ ness Change Results19 2.2.4.2.3 Weight Changes 23 2.2.5 Phase II Environmental Testing 27 II I -ii TALIO ONET TABLE OF...CONTENTS (CONT’D) SECTION PAGE 2.3 Phase I Analysis and Design 27 2.3.1 Sizing and Optimizing AR 27 2.3.2 Valve Sizing 36 2.3.3 Pistons Side Load and Rocker

  20. Accessing the inaccessible: making (successful) field observations at tidewater glacier termini

    NASA Astrophysics Data System (ADS)

    Kienholz, C.; Amundson, J. M.; Jackson, R. H.; Motyka, R. J.; Nash, J. D.; Sutherland, D.

    2017-12-01

    Glaciers terminating in ocean water (tidewater glaciers) show complex dynamic behavior driven predominantly by processes at the ice-ocean interface (sedimentation, erosion, iceberg calving, submarine melting). A quantitative understanding of these processes is required, for example, to better assess tidewater glaciers' fate in our rapidly warming environment. Lacking observations close to glacier termini, due to unpredictable risks from calving, hamper this understanding. In an effort to remedy this lack of knowledge, we initiated a large field-based effort at LeConte Glacier, southeast Alaska, in 2016. LeConte Glacier is a regional analog for many tidewater glaciers, but better accessible and observable and thus an ideal target for our multi-disciplinary effort. Our ongoing campaigns comprise measurements from novel autonomous vessels (temperature, salinity and current) in the immediate proximity of the glacier terminus and additional surveys (including multibeam bathymetry) from boats and moorings in the proglacial fjord. These measurements are complemented by iceberg and glacier velocity measurements from time lapse cameras and a portable radar interferometer situated above LeConte Bay. GPS-based velocity observations and melt measurements are conducted on the glacier. These measurements provide necessary input for process-based understanding and numerical modeling of the glacier and fjord systems. In the presentation, we discuss promising initial results and lessons learned from the campaign.

  1. A new species of Deltaspis Audinet-Serville (Coleoptera: Cerambycidae: Cerambycinae) from Mexico.

    PubMed

    Eya, Bryan K

    2017-03-27

    As currently defined, the genus Deltaspis Audinet-Serville, 1834, contains 16 species ranging in distribution from the southwestern United States to eastern Mexico. However, the generic distinction between Deltaspis and its closely allied genera, such as Crossidius LeConte, 1851 and Muscidora Thomson, 1864, is in need of clarification. According to Audinet-Serville, Deltaspis is so named due to its distinctive triangular scutellum (i.e., Δετα, delta, ασπιζ écusson), which is actually a commonly shared character of all these genera. Members of the tribe Trachyderini Dupont (1836), which includes the above genera, also have mandibles with an emarginate-truncate apex with the edge chisel-like or bifid. This modification of mouthpart appears to be for consumption of pollen and/or petals from composite flowers visited by the adult beetles (Krenn et al., 2005; Beierl & Barchet-Beierl, 1999). Other genera from this tribe with this modification of mandibles from North America, and mostly from Mexico, include: Chemsakiella Monné, 2006, Giesbertia Chemsak & Linsley, 1984, Hoegea Bates, 1885, Neocrossidius Chemsak, 1959, Paroxoplus Chemsak, 1959, Plionoma Casey, 1912, Schizax LeConte, 1873, and Tylosis LeConte, 1850. The remainder of Trachyderini genera have unmodified or simple mandibles with apex acute.

  2. Evaluation of autonomous recording units for detecting 3 species of secretive marsh birds

    USGS Publications Warehouse

    Sidie-Slettehahl, Anna M.; Jensen, Kent C.; Johnson, Rex R.; Arnold, Todd W.; Austin, Jane; Stafford, Joshua D.

    2015-01-01

    Population status and habitat use of yellow rails (Coturnicops noveboracensis), Nelson's sparrows (Ammodramus nelsoni), and Le Conte's sparrows (A. leconteii) are poorly known, so standardized surveys of these species are needed to inform conservation planning and management. A protocol for monitoring secretive marsh birds exists; however, these species regularly call at night and may be missed during early morning surveys. We tested the effectiveness of autonomous recording units (hereafter, recording units) to survey these species by analyzing recorded vocalizations using bioacoustics software. We deployed 22 recording units at 54 sites in northern Minnesota and eastern North Dakota, USA, and conducted traditional broadcast surveys during May–June, 2010 and 2011. We compared detection probabilities between recording units and standard monitoring protocols using robust-design occupancy models. On average, recording units detected 0.59 (SE = 0.11) fewer Le Conte's sparrows, 0.76 (SE = 0.15) fewer Nelson's sparrows, and 1.01 (SE = 0.14) fewer yellow rails per survey than were detected using the standard protocol. Detection probabilities using the standard protocol averaged 0.95 (yellow rail; 95% CI = 0.86–0.98), 0.93 (Le Conte's sparrow; 95% CI = 0.78–0.98), and 0.89 (Nelson's sparrow; 95% CI = 0.56–0.98), but averaged 0.71 (yellow rail; 95% CI = 0.56–0.83), 0.61 (Le Conte's sparrow; 95% CI = 0.42–0.78), and 0.51 (Nelson's sparrow; 95% CI = 0.19–0.82) using recording units. Reduced detection by recording units was likely due to the ability of human listeners to identify birds calling at greater distances. Recording units may be effective for surveying nocturnal secretive marsh birds if investigators correct for differential detectability. Reduced detectability may be outweighed by the increased spatial and temporal coverage feasible with recording units.

  3. Intermittent and continuous high-intensity exercise training induce similar acute but different chronic muscle adaptations.

    PubMed

    Cochran, Andrew J R; Percival, Michael E; Tricarico, Steven; Little, Jonathan P; Cermak, Naomi; Gillen, Jenna B; Tarnopolsky, Mark A; Gibala, Martin J

    2014-05-01

    High-intensity interval training (HIIT) performed in an 'all-out' manner (e.g. repeated Wingate tests) is a time-efficient strategy to induce skeletal muscle remodelling towards a more oxidative phenotype. A fundamental question that remains unclear, however, is whether the intermittent or 'pulsed' nature of the stimulus is critical to the adaptive response. In study 1, we examined whether the activation of signalling cascades linked to mitochondrial biogenesis was dependent on the manner in which an acute high-intensity exercise stimulus was applied. Subjects performed either four 30 s Wingate tests interspersed with 4 min of rest (INT) or a bout of continuous exercise (CONT) that was matched for total work (67 ± 7 kJ) and which required ∼4 min to complete as fast as possible. Both protocols elicited similar increases in markers of adenosine monophosphate-activated protein kinase (AMPK) and p38 mitogen-activated protein kinase activation, as well as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) mRNA expression (main effects for time, P ≤ 0.05). In study 2, we determined whether 6 weeks of the CONT protocol (3 days per week) would increase skeletal muscle mitochondrial content to a similar extent to what we have previously reported after 6 weeks of INT. Despite similar acute signalling responses to the CONT and INT protocols, training with CONT did not increase the maximal activity or protein content of a range of mitochondrial markers. However, peak oxygen uptake was higher after CONT training (from 45.7 ± 5.4 to 48.3 ± 6.5 ml kg(-1) min(-1); P < 0.05) and 250 kJ time trial performance was improved (from 26:32 ± 4:48 to 23:55 ± 4:16 min:s; P < 0.001) in our recreationally active participants. We conclude that the intermittent nature of the stimulus is important for maximizing skeletal muscle adaptations to low-volume, all-out HIIT. Despite the lack of skeletal muscle mitochondrial adaptations, our data show that a training programme based on a brief bout of high-intensity exercise, which lasted <10 min per session including warm-up, and performed three times per week for 6 weeks, improved peak oxygen uptake in young healthy subjects. © 2014 The Authors. Experimental Physiology © 2014 The Physiological Society.

  4. Larvae and pupae of two North American darkling beetles (Coleoptera, Tenebrionidae, Stenochiinae), Glyptotus cribratus LeConte and Cibdelis blaschkei Mannerheim, with notes on ecological and behavioural similarities.

    PubMed

    Steiner, Warren E

    2014-01-01

    THIS STUDY DESCRIBES AND ILLUSTRATES THE LARVAE AND PUPAE OF TWO NORTH AMERICAN DARKLING BEETLES (COLEOPTERA: Tenebrionidae) in the subfamily Stenochiinae, Glyptotus cribratus LeConte from the southeastern United States, and Cibdelis blaschkei Mannerheim from California. Both species inhabit forested regions where adults and larvae occur in soft rotten dry wood of dead branches on living trees or in sections recently fallen from them. Species identity was confirmed by rearing of adults and pupae and the discovery of both in pupal cells with associated exuvia. Specimen label data and notes on habitats are provided. Antipredator defense structures and behaviour are noted for larvae and pupae of both species.

  5. New Coleoptera records from New Brunswick, Canada: Cerambycidae

    PubMed Central

    Webster, Reginald P.; Sweeney, Jon D.; DeMerchant, Ian; Silk, Peter J.; Mayo, Peter

    2012-01-01

    Abstract Five species of Cerambycidae, Acmaeops discoideus (Haldeman), Anelaphus villosus (Fabricius), Phymatodes species (CNC sp. n. #1), Sarosesthes fulminans (Fabricius), and Urgleptus signatus (LeConte) are newly recorded for New Brunswick, Canada. All but Acmaeops villosus are new to the Maritime provinces. Phymatodes testaceus (Linnaeus) is removed from the faunal list of the province as a result of mislabeled specimens, records of Phymatodes maculicollis LeConte are presented confirming the presence of this species in New Brunswick, and the first recent records ofNeospondylis upiformis (Mannerheim) are presented. Additional records are given for the recently recorded Phymatodes aereus (Newman), indicating a wider distribution in the province. Collection data, habitat data, and distribution maps are presented for each species. PMID:22539899

  6. Large scale clear-water local pier scour experiments

    USGS Publications Warehouse

    Sheppard, D.M.; Odeh, M.; Glasser, T.

    2004-01-01

    Local clear-water scour tests were performed with three different diameter circular piles (0. 114, 0.305, and 0.914 m), three different uniform cohesionless sediment diameters (0.22, 0.80, and 2.90 mm) and a range of water depths and flow velocities. The tests were performed in the 6.1 m wide, 6.4 m deep, and 38.4 m long flume at the United States Geological Survey Conte Research Center in Turners Falls, Mass. These tests extend local scour data obtained in controlled experiments to prototype size piles and ratios of pile diameter to sediment diameter to 4,155. Supply water for this flow through flume was supplied by a hydroelectric power plant reservoir and the concentration of suspended fine sediment (wash load) could not be controlled. Equilibrium scour depths were found to depend on the wash load concentration. ?? ASCE.

  7. Hippocampus lesions induced deficits in social and spatial recognition in Octodon degus.

    PubMed

    Uekita, Tomoko; Okanoya, Kazuo

    2011-06-01

    Previous studies of rodents reported that the hippocampus plays an important role in social behavior as well as spatial behavior. However, there are inconsistencies between reports of the effects of hippocampal lesions on social behavior. The present study sought to clarify the aspects of social behavior in which the hippocampus plays a role in the degu, Octodon degus, a social rodent. We examined the effects of hippocampal lesions on social behavior in the degu using familiar and novel partners. When placed in a familiar environment with a familiar partner after surgery, sham operation control (S.Cont) degus exhibited affinitive behavior longer compared with hippocampal lesioned (HPC) degus. In a novel environment, S.Cont degus exhibited longer aggressive behavior toward novel partners, and longer affinitive behavior with familiar partners compared with HPC degus. HPC degus did not show evidence of differentiation in social behavior, regardless of partner's novelty. The results of an anxiety test confirmed that these findings could not be attributed to changes in emotional state. We conducted an object-recognition test with the same subjects. HPC degus showed an impairment in spatial recognition but not object recognition. Taken together, these results suggest that the degu hippocampus plays an important role not only in spatial recognition but also social recognition. The changes in social behavior resulting from hippocampal lesions were interpreted as due to an impairment of social recognition rather than an impairment in novelty detection. Copyright © 2011 Elsevier B.V. All rights reserved.

  8. Two-Component Structure of the Radio Source 0014+813 from VLBI Observations within the CONT14 Program

    NASA Astrophysics Data System (ADS)

    Titov, O. A.; Lopez, Yu. R.

    2018-03-01

    We consider a method of reconstructing the structure delay of extended radio sources without constructing their radio images. The residuals derived after the adjustment of geodetic VLBI observations are used for this purpose. We show that the simplest model of a radio source consisting of two point components can be represented by four parameters (the angular separation of the components, the mutual orientation relative to the poleward direction, the flux-density ratio, and the spectral index difference) that are determined for each baseline of a multi-baseline VLBI network. The efficiency of this approach is demonstrated by estimating the coordinates of the radio source 0014+813 observed during the two-week CONT14 program organized by the International VLBI Service (IVS) in May 2014. Large systematic deviations have been detected in the residuals of the observations for the radio source 0014+813. The averaged characteristics of the radio structure of 0014+813 at a frequency of 8.4 GHz can be calculated from these deviations. Our modeling using four parameters has confirmed that the source consists of two components at an angular separation of 0.5 mas in the north-south direction. Using the structure delay when adjusting the CONT14 observations leads to a correction of the average declination estimate for the radio source 0014+813 by 0.070 mas.

  9. Mood and selective attention in the cold: the effect of interval versus continuous exercise.

    PubMed

    Muller, Matthew D; Muller, Sarah M; Kim, Chul-Ho; Ryan, Edward J; Gunstad, John; Glickman, Ellen L

    2011-07-01

    Both mood and cognitive function are altered in cold environments. Body warming through exercise may improve Stroop interference score and lessen total negative mood. The purpose of this study was to determine the effect of equal caloric bouts of interval (INT) and continuous (CONT) exercise on mood and selective attention in the cold. Eleven young men underwent two experimental trials in 5°C air. Both trials consisted of 90 min acute cold exposure (ACE), 30 min exercise (INT vs. CONT), and 60 min recovery (REC). The Profile of Mood States (POMS) and Stroop Color Word Test (SCWT) were administered at four time points. Mean body temperature decreased during ACE, increased during exercise, and decreased during REC. Repeated measures analysis of variance revealed a main effect for time for several of the POMS sub scores. In particular, negative mood was significantly decreased after exercise relative to ACE and then significantly increased during REC. Further, CONT appears to be more effective than INT at decreasing negative mood. Components of the SCWT supported both the arousal and distraction theories for simple perception, but no significant effects were shown for the interference score. In the cold, exercise decreases negative mood but does not appear to affect selective attention. Further mechanistic studies could determine the best mode and intensity of exercise for improving cognitive function in the cold.

  10. About Stressful Situations

    MedlinePlus

    ... Coping Skills (cont.) 2. Commit to a Positive Attitude A positive attitude helps stop you from being dragged down by unhappy feelings. A positive attitude also boosts the problem solving that a stressful ...

  11. Larvae and pupae of two North American darkling beetles (Coleoptera, Tenebrionidae, Stenochiinae), Glyptotus cribratus LeConte and Cibdelis blaschkei Mannerheim, with notes on ecological and behavioural similarities

    PubMed Central

    Steiner, Warren E.

    2014-01-01

    Abstract This study describes and illustrates the larvae and pupae of two North American darkling beetles (Coleoptera: Tenebrionidae) in the subfamily Stenochiinae, Glyptotus cribratus LeConte from the southeastern United States, and Cibdelis blaschkei Mannerheim from California. Both species inhabit forested regions where adults and larvae occur in soft rotten dry wood of dead branches on living trees or in sections recently fallen from them. Species identity was confirmed by rearing of adults and pupae and the discovery of both in pupal cells with associated exuvia. Specimen label data and notes on habitats are provided. Antipredator defense structures and behaviour are noted for larvae and pupae of both species. PMID:25009432

  12. Effect of diversified crop rotations on groundwater levels and crop water productivity in the North China Plain

    NASA Astrophysics Data System (ADS)

    Yang, Xiaolin; Chen, Yuanquan; Pacenka, Steven; Gao, Wangsheng; Ma, Li; Wang, Guangya; Yan, Peng; Sui, Peng; Steenhuis, Tammo S.

    2015-03-01

    Water shortage is the major bottleneck that limits sustainable yield of agriculture in the North China Plain. Due to the over-exploitation of groundwater for irrigating the winter wheat-summer maize double cropping systems, a groundwater crisis is becoming increasingly serious. To help identify more efficient and sustainable utilization of the limited water resources, the water consumption and water use efficiency of five irrigated cropping systems were calculated and the effect of cropping systems on groundwater table changes was estimated based on a long term field experiment from 2003 to 2013 in the North China Plain interpreted using a soil-water-balance model. The five cropping systems included sweet potato → cotton → sweet potato → winter wheat-summer maize (SpCSpWS, 4-year cycle), ryegrass-cotton → peanuts → winter wheat-summer maize (RCPWS, 3-year cycle), peanuts → winter wheat-summer maize (PWS, 2-year cycle), winter wheat-summer maize (WS, 1-year cycle), and continuous cotton (Cont C). The five cropping systems had a wide range of annual average actual evapotranspiration (ETa): Cont C (533 mm/year) < SpCSpWS (556 mm/year) < PWS (615 mm/year) < RCPWS (650 mm/year) < WS rotation (734 mm/year). The sequence of the simulated annual average groundwater decline due to the five cropping systems was WS (1.1 m/year) > RCPWS (0.7 m/year) > PWS (0.6 m/year) > SPCSPWS and Cont C (0.4 m/year). The annual average economic output water use efficiency (WUEe) increased in the order SpCSpWS (11.6 yuan ¥ m-3) > RCPWS (9.0 ¥ m-3) > PWS (7.3 ¥ m-3) > WS (6.8 ¥ m-3) > Cont C (5.6 ¥ m-3) from 2003 to 2013. Results strongly suggest that diversifying crop rotations could play a critically important role in mitigating the over-exploitation of the groundwater, while ensuring the food security or boosting the income of farmers in the North China Plain.

  13. The advertisement and aggressive calls of Rhinella abei (Baldissera, Caramaschi, and Haddad, 2004) (Anura: Bufonidae) from Campo Largo, Paraná, Brazil.

    PubMed

    Batista, Vinicius Guerra; Ramalho, Werther Pereira; Amaral, Diogo Ferreira Do; Maciel, Natan Medeiros; Bastos, Rogério Pereira

    2016-05-04

    Rhinella abei is a medium-sized species (snout-to-vent length 57.0-76.4 mm in males; 60.4-83.9 mm in females-Baldissera et al. 2004) of the Rhinella crucifer species group, distributed in the Brazilian Atlantic Rainforest, from the State of Paraná to northern Rio Grande do Sul (Frost 2016). It is recorded in forested areas (Conte & Rossa-Feres 2007), or while breeding along forest edges and open habitats. Information on advertisement calls of species in the R. crucifer group is available for R. casconi, R. crucifer, R. inopina and R. ornata (Andrade et al. 2015; Heyer et al. 1990; Oliveira et al. 2014; Roberto et al. 2014). Here we describe the advertisement and aggressive calls of R. abei recorded in the municipality of Campo Largo (25.507472° S, 49.376632° W, datum "WGS84"), southeast State of Paraná, Brazil.

  14. The subtribes and genera of the tribe Listroderini (Coleoptera, Curculionidae, Cyclominae): Phylogenetic analysis with systematic and biogeographical accounts

    PubMed Central

    Morrone, Juan J.

    2013-01-01

    Abstract The phylogenetic relationships of the genera of Listroderini LeConte, 1876 are analyzed based on 58 morphological characters. The genera are grouped in four clades, which are given subtribal status: Macrostyphlina new subtribe (Adioristidius, Amathynetoides, Andesianellus, Macrostyphlus, Nacodius and Puranius), Palaechthina Brinck, 1948 (Anorthorhinus, Gunodes, Haversiella, Inaccodes, Listronotus, Neopachytychius, Palaechthus, Palaechtodes, Steriphus and Tristanodes), Falklandiina new subtribe (Falklandiellus, Falklandiopsis, Falklandius, Gromilus, Lanteriella, Liparogetus, Nestrius and Telurus), and Listroderina (Acroriellus, Acrorius, Acrostomus, Antarctobius, Germainiellus, Hyperoides, Lamiarhinus, Listroderes, Methypora, Philippius, Rupanius and Trachodema). The subtribes are characterized and keys to identify them and their genera are provided. Listroderini have four main biogeographical patterns: Andean (Macrostyphlina), Andean-New Zealand (Falklandiina), Andean-Neotropical-Australian (Listroderina) and Andean-Neotropical-Australian-New Zealand-Nearctic-Tristan da Cunha-Gough islands (Palaechthina). Geographical paralogy, particularly evident in the Subantarctic subregion of the Andean region, suggests that Listroderini are an ancient Gondwanic group, in which several extinction events might have obscured relationships among the areas. PMID:23794805

  15. Framework for the Intelligent Transportation System (ITS) Evaluation : ITS Integration Activities

    DOT National Transportation Integrated Search

    2006-08-01

    Intelligent Transportation Systems (ITS) represent a significant opportunity to improve the efficiency and safety of the surface transportation system. ITS includes technologies to support information processing, communications, surveillance and cont...

  16. Effects of pitfall trap preservative on collections of carabid beetles (Coleoptera: Carabidae)

    USGS Publications Warehouse

    McCravy, K.W.; Willand, J.E.

    2007-01-01

    Effects of six pitfall trap preservatives (5% acetic acid solution, distilled water, 70% ethanol, 50% ethylene glycol solution, 50% propylene glycol solution, and 10% saline solution) on collections of carabid beetles (Coleoptera: Carabidae) were studied in a west-central Illinois deciduous forest from May to October 2005. A total of 819 carabids, representing 33 species and 19 genera, were collected. Saline produced significantly fewer captures than did acetic acid, ethanol, ethylene glycol, and propylene glycol, while distilled water produced significantly fewer captures than did acetic acid. Significant associations between numbers of captures and treatment were seen in four species: Amphasia interstitialis (Say), Calathus opaculus LeConte, Chlaenius nemoralis Say, and Cyclotrachelus sodalis (LeConte). Results of this study suggest that type of preservative used can have substantial effects on abundance and species composition of carabids collected in pitfall traps.

  17. Dronedarone administration prevents body weight gain and increases tolerance of the heart to ischemic stress: a possible involvement of thyroid hormone receptor alpha1.

    PubMed

    Pantos, Constantinos; Mourouzis, Iordanis; Malliopoulou, Vassiliki; Paizis, Ioannis; Tzeis, Stylianos; Moraitis, Panagiotis; Sfakianoudis, Konstantinos; Varonos, Dennis D; Cokkinos, Dennis V

    2005-01-01

    Hypothyroid heart displays a phenotype of cardioprotection against ischemia and this study investigated whether administration of dronedarone, an amiodarone-like compound that has been shown to preferentially antagonize thyroid hormone binding to thyroid hormone receptor alpha1 (TRalpha1), results in a similar effect. Dronedarone was given in Wistar rats (90 mg/kg, once daily (od) for 2 weeks) (DRON), while untreated animals served as controls (CONT). Hypothyroidism (HYPO) was induced by propylthiouracil administration. Isolated rat hearts were perfused in Langendorff mode and subjected to 20 minutes of zero-flow global ischemia (I) followed by 45 minutes of reperfusion (R). 3,5,3' Triiodothyronine remained unchanged while body weight and food intake were reduced. alpha-Myosin heavy chain (alpha-MHC) decreased in DRON while beta-myosin heavy chain (beta-MHC) and sarcoplasmic reticulum Ca2+ adenosine triphosphatase (ATPase) expression (SERCA) was similar to CONT. In HYPO, alpha-MHC and SERCA were decreased while beta-MHC was increased. Myocardial glycogen content was increased in both DRON and HYPO. In DRON, resting heart rate and contractility were reduced and ischemic contracture was significantly suppressed while postischemic left ventricular end-diastolic pressure and lactate dehydrogenase release (IU/L min) after I/R were significantly decreased. In conclusion, dronedarone treatment results in cardioprotection by selectively mimicking hypothyroidism. This is accompanied by a reduction in body weight because of the suppression of food intake. TRs might prove novel pharmacologic targets for the treatment of cardiovascular illnesses.

  18. The Microcode for the Control Processor of the ARO (Array Oriented Processor) Array Processor.

    DTIC Science & Technology

    1983-08-01

    oiNi .TADDR=DBASE+MODE" 4CONT ŕWAfT’ FOR MEM, MORE", MOV) ,DRO BSX "S IGN EXT, MORE" SADD D FLDSEI,(6,3),IMN TADT)R=5+ 1 JMP I NDE-’XEI) "JU> IP ’ T1...JDTV1: YIP DIVI; TDIV2: Y,’ IP DIV2; JASHII: JMP ASHI; 4 JASH2: JMP AS112; JXOR1: YIP XDRI; JXOR2: YIP XOR2; JSOB: JMP SOB; JBPL: JMP BPL; JBMI: YIP BMI;0...JBHI: JMP BHill JBLOS: J! IP BLOS; JBVC: YIP BVC; JBWS: JMP BVS; JBCC: JMP BCC; JBCS: YIP BCS; JEMT: YIP EMT; JTRAP: YIP TRAPQ; JCLR6: YIP CLR6; JCOII

  19. GROUNDWATER AND SOIL REMEDIATION USING ELECTRICAL FIELD

    EPA Science Inventory

    Enhancements of contaminants removal and degradation in low permeability soils by electrical fields are achieved by the processes of electrical heating, electrokinetics, and electrochemical reactions. Electrical heating increases soil temperature resulting in the increase of cont...

  20. Houston North Freeway Contraflow Lane Demonstration.

    DOT National Transportation Integrated Search

    1982-12-01

    On August 28, 1979, the Metropolitan Transit Authority (METRO) of Harris County in Texas, in cooperation with the Texas State Department of Highways and Public Transportation and the Urban Mass Transportation Administration, began operation of a cont...

  1. Field evaluation of a portable gyratory compactor : final report.

    DOT National Transportation Integrated Search

    2002-06-01

    Application of quality management concepts to asphalt paving evolved because recipe specifications frequently proved inadequate for ensuring pavement performance. Quality management of asphalt concrete is founded on the premise that the producer cont...

  2. Relationship between the prognostic value of ventilatory efficiency and age in patients with heart failure.

    PubMed

    Kato, Yuko; Suzuki, Shinya; Uejima, Tokuhisa; Semba, Hiroaki; Nagayama, Osamu; Hayama, Etsuko; Arita, Takuto; Yagi, Naoharu; Kano, Hiroto; Matsuno, Shunsuke; Otsuka, Takayuki; Oikawa, Yuji; Kunihara, Takashi; Yajima, Junji; Yamashita, Takeshi

    2018-05-01

    Background Ventilatory efficiency decreases with age. This study aimed to investigate the prognostic significance and cut-off value of the minute ventilation/carbon dioxide production (VE/VCO 2 ) slope according to age in patients with heart failure. Methods and results We analysed 1501 patients with heart failure from our observational cohort who performed maximal symptom-limited cardiopulmonary exercise testing and separated them into three age groups (≤55 years, 56-70 years and ≥71 years) in total and according to the three ejection fraction categories defined by European Society of Cardiology guidelines. The endpoint was set as heart failure events, hospitalisation for heart failure or death from heart failure. The VE/VCO 2 slope increased with age. During the median follow-up period of 4 years, 141 heart failure (9%) events occurred. In total, univariate Cox analyses showed that the VE/VCO 2 slope (cont.) was significantly related to heart failure events, while on multivariate analysis, the prognostic significance of the VE/VCO 2 slope (cont.) was poor, accompanied by a significant interaction with age ( P < 0.0001). The cut-off value of the VE/VCO 2 slope increased with the increase in age in not only the total but also the sub-ejection fraction categories. Multivariate analyses with a stepwise method adjusted for estimated glomerular filtration rate, peak oxygen consumption, atrial fibrillation and brain natriuretic peptide, showed that the predictive value of the binary VE/VCO 2 slope separated by the cut-off value varied according to age. There was a tendency for the prognostic significance to increase with age irrespective of ejection fraction. Conclusion The prognostic significance and cut-off value of the VE/VCO 2 slope may increase with advancing age.

  3. PROJECT HOPE (HEALTH OPPORTUNITIES FOR PEOPLE EVERYWHERE)

    EPA Science Inventory

    Project HOPE's (Health Opportunities for People Everywhere) missionis to achieve sustainable advances in health care around the world by implementing health education programs, conducting health policy research, and providing humanitarian assistance in areas of need; thereby cont...

  4. Financial physics

    NASA Astrophysics Data System (ADS)

    Feigenbaum, James

    2003-10-01

    In this introduction to the burgeoning field of econophysics, we review the application of self-organized criticality to economics, the Cont-Bouchaud percolation model, multiple-strategy agent-based models of financial markets, the minority game, and log-periodic precursors to financial crashes.

  5. Containerization policy : considering increased load weight for certain circumstances of freight in Wisconsin.

    DOT National Transportation Integrated Search

    2009-06-01

    Many businesses in Wisconsin export their goods throughout the world. An efficient way of doing business internationally is : through containerized shipments. This research discovered that Wisconsins weight laws for transporting international cont...

  6. Berkeley Lab 2nd Grader Outreach

    ScienceCinema

    Scoggins, Jackie; Louie, Virginia

    2017-12-11

    The Berkeley Lab IT Department sponsored a community outreach program aimed at teaching young children about computers and networks. Second graders from LeConte Elementary School joined Lab IT Staff for a day of in-depth exercises and fun.

  7. Review of the Nearctic genus Lacconotus LeConte (Coleoptera, Mycteridae, Eurypinae)

    PubMed Central

    Pollock, Darren; Majka, Christopher G.

    2012-01-01

    Abstract Lacconotus LeConte, the sole Nearctic representative of the eurypine Mycteridae, is revised, based on morphological features of adults. The following syn. n. is proposed: Lacconotus pallidus Van Dyke, 1928 = Lacconotus pinicola Horn, 1879. The former is a light-colored form with a southern California distribution. A subgen. n., Alcconotus, is described for Lacconotus pinicola, producing the following comb. n.: Lacconotus (Alcconotus) pinicola (Horn). A lectotype is designated for Lacconotus pinicola. A key separating the two subgenera and species is provided, as are photographs and illustrations of salient structures of adults, and maps showing collection localities. Lacconotus punctatus is newly recorded in Alabama, Arkansas, Massachusetts, Oklahoma, Texas, and Wisconsin; Lacconotus pinicola is newly recorded in Arizona and Utah in the USA, and Baja California Norte in Mexico. Phenology information shows a north-to-south gradation in occurrence time. PMID:22303123

  8. Three pioneers of comparative psychology in America, 1843-1890: Lewis H. Morgan, John Bascom, and Joseph LeConte.

    PubMed

    Johnston, Timothy D

    2003-02-01

    Scientific comparative psychology in America dates from the mid-1890s, but there is a body of earlier literature on the topic, written during a period of theistic debates over Darwinian evolution. The anthropologist Lewis H. Morgan rejected instinct as an explanation of animal behavior in 1843 and defended the mental similarities between animals and humans, although he was not an evolutionist. John Bascom's textbook Comparative Psychology (1878) is the earliest American work to use that title, and its theistic approach anticipates some arguments found in much later evolutionary works. Beginning in 1860, the geologist Joseph LeConte, who is well known for defending the compatibility of evolution and religion, wrote several articles in which he outlined a comparative evolutionary approach to psychological problems. However, these writers did not establish a coherent research tradition and were ignored by the "New Psychologists" of the 1880s.

  9. An annotated catalogue of the type material of Elateroidea Leach, 1815 (Coleoptera) deposited in the Coleoptera collection of the Museum of Zoology of the University of São Paulo, Brazil.

    PubMed

    Ferreira, Vinicius De Souza

    2015-03-25

    The Museum of Zoology of the University of São Paulo (MZSP) houses one of the most important Coleoptera collections of Brazil and Neotropical Region with nearly 900,000 adult mounted material and about 1,500,000 specimens to be mounted. The superfamily Elateroidea Leach, 1815 (including Cantharoidea) comprises about 24,077 described species in 17 families. The MZSP owns type material of Brachypsectridae LeConte & Horn, 1883, Cantharidae, 1856 (1815), Cerophytidae Latreille, 1834, Elateridae Leach 1815, Eucnemidae Eschscholtz, 1829, Lampyridae Rafinesque, 1815, Lycidae Laporte, 1836, Phengodidae LeConte, 1861 and Rhinorhipidae Lawrence, 1988. This catalogue includes type material of 166 species distributed in 69 genera. Among 1,223 type specimens, are 86 holotypes, 1,133 paratypes, 2 allotypes, 1 lectotype and 1 paralectotype.

  10. Laboratory evaluation of 100% fly ash cementitious systems containing Ekkomaxx.

    DOT National Transportation Integrated Search

    2013-09-01

    Long-lasting, durable concrete is a must have for DOTs in todays construction : and economic climate. Many entities are turning to alternative concrete : mixtures, such as ternary mixtures, lower w/cm ratios, lower cementitious : materials cont...

  11. Early Geologic Education in California--Berkeley and Stanford Show the Way.

    ERIC Educational Resources Information Center

    Norris, Robert M.

    1981-01-01

    Traces the early history of geological education in California universities, with emphasis upon programs at Berkeley and Stanford. Among the pioneers in the field were Joseph LeConte, Andrew C. Lawson, and John C. Branner. (WB)

  12. BACULOVIRUS REPLICATION ALTERS HORMONE-REGULATED HOST DEVELOPMENT.

    EPA Science Inventory

    The baculovirus Lymantria dispar nuclear polyhedrosis virus interferes with insect larval development by altering the host's hormonal system. The level of haemolymph ecdysteroids, the insect moulting hormone, was found to be higher in virus-infected larvae than in uninfected cont...

  13. MEMBRANE TECHNOLOGIES FOR REMEDIATING CONTAMINATED SOILS: A CRITICAL REVIEW

    EPA Science Inventory

    Regulatory compliance requires the cleanup of soils contaminated with toxic organic and metallic compounds. Several chemical and thermal detoxification technologies have been tested on soils excavated from contaminated sites. Soil washing with aqueous solutions transfers the cont...

  14. Development and validation of educational technology for venous ulcer care.

    PubMed

    Benevides, Jéssica Lima; Coutinho, Janaina Fonseca Victor; Pascoal, Liliane Chagas; Joventino, Emanuella Silva; Martins, Mariana Cavalcante; Gubert, Fabiane do Amaral; Alves, Allana Mirella

    2016-04-01

    To develop and validate an educational technology venous ulcers care. Methodological study conducted in five steps: Situational diagnosis; literature review; development of texts, illustrations and layout; apparent and content validity by the Content Validity Index, assessment of Flesch Readability Index; and pilot testing. The developed technology was a type of booklet entitled Booklet for Venous Ulcers Care, consisting of seven topics: Diet and food intake, walking and light exercise, resting with elevated leg, bandage care, compression therapy, family support, and keeping healthy habits. The apparent validity revealed minimal agreement of 85.7% in the clarity and comprehensibility. The total content validity index was 0.97, the Flesch Readability Index was 75%, corresponding to the reading "fairly easy". The pilot test showed that 100% of people with venous ulcers evaluated the text and the illustrations as understandable, as appropriate. The educational technology proved to be valid for the appearance and content with potential for use in clinical practice. Construir e validar uma tecnologia educativa para cuidados com úlcera venosa. Estudo metodológico realizado em cinco fases: diagnóstico situacional; revisão da literatura; desenvolvimento de textos, ilustrações e diagramação; validade de aparência e de conteúdo pelo Índice de Validade de Conteúdo, avaliação do Índice de Legibilidade de Flesch; e teste piloto. A tecnologia desenvolvida foi do tipo cartilha intitulada Cartilha para cuidados com úlcera venosa, constituída de sete tópicos: Alimentação, Caminhadas e exercícios leves, Repouso com a perna elevada, Cuidados com o curativo, Terapia compressiva, Apoio familiar, e manter hábitos saudáveis. A validade aparente revelou concordância mínima de 85,7% na clareza e compreensibilidade. O Índice de Validade de Conteúdo total foi de 0,97, o Índice de legibilidade de Flesch foi de 75%, o que correspondeu à leitura "razoavelmente fácil". O teste piloto revelou que 100% das pessoas com úlcera venosa avaliaram o texto como compreensivo e as ilustrações, como adequadas. A tecnologia educativa mostrou-se válida quanto à aparência e ao conteúdo, com potencial de utilização na prática clínica.

  15. Espectroscopia infravermelha de núcleos ativos de galáxias: resultados adicionais

    NASA Astrophysics Data System (ADS)

    Rodríguez Ardila, A.; Viegas, S.; Pastoria, M. G.

    2003-08-01

    Apresentamos resultados parciais de um levantamento espectroscópico na região do infravermelho próximo (NIR) realizado em 30 núcleos ativos de galáxias (AGN), incluindo vários objetos selecionados do catálogo PG com z de até 0.55. O objetivo é estudar a natureza do contínuo observado e as condições físicas do gas emissor. Todas as fontes de tipo 1 apresentam uma mudança na inclinação do contínuo na região de 1.2mm, associada ao término da contribuição do contínuo emitido pelo AGN e ao início da contribuição do contínuo emitido pela poeira quente atribuída ao tórus que rodeia a fonte central. O índice espectral associado à segunda contribuição varia apreciavelmente de objeto para objeto. Este resultado é comparado com distribuições espectrais de energia preditas por modelos de toroides para testar a validez do modelo unificado. A partir das linhas de FeII observado nos espectros deriva-se, pela primeira vez nessa região espectral, um template empírico de FeII para estudar a intensidade e a origem dessa emissão. A intensidade do FeII é estudada em conjunto com aquela da região visível e comparada às predições de modelos teóricos que incluem fluorescência de Lya, excitação colisional e auto-fluorescência como mecanismos dominantes de exitação. Encontra-se que os dois primeiros processos dominam na formação do espectro de FeII observado. Indicadores de avermelhamento, entre eles Brg/Pab, Pab/Pag, Pab/Pad e [FeII] 1.257/1.644 mm são utilizados para mapear a distribuição de poeira nas regiões emissoras de linhas. Encontra-se valores de extinção Av~3 associados ao último indicador e valores significativamente menores (Av~1.5) para os restantes, o que sugere que o [FeII] se forma em uma região separada da maior parte do gás emissor de linhas estreitas.

  16. Effect of egg storage duration and brooding temperatures on chick growth, intestine morphology and nutrient transporters.

    PubMed

    Yalcin, S; Gursel, I; Bilgen, G; Horuluoglu, B H; Gucluer, G; Izzetoglu, G T

    2017-10-01

    The effects of egg storage duration (ESD) and brooding temperature (BT) on BW, intestine development and nutrient transporters of broiler chicks were investigated. A total of 396 chicks obtained from eggs stored at 18°C for 3 days (ESD3-18°C) or at 14°C for 14 days (ESD14-14°C) before incubation were exposed to three BTs. Temperatures were initially set at 32°C, 34°C and 30°C for control (BT-Cont), high (BT-High) and low (BT-Low) BTs, respectively. Brooding temperatures were decreased by 2°C each at days 2, 7, 14 and 21. Body weight was measured at the day of hatch, 2, 7, 14, 21, 28 and 42. Cloacal temperatures of broilers were recorded from 1 to 14 days. Intestinal morphology and gene expression levels of H+-dependent peptide transporter (PepT1) and Na-dependent glucose (SGLT1) were evaluated on the day of hatch and 14. Cloacal temperatures of chicks were affected by BTs from days 1 to 8, being the lowest for BT-Low chicks. BT-High resulted in the heaviest BWs at 7 days, especially for ESD14-14°C chicks. This result was consistent with longer villus and larger villus area of ESD14-14°C chicks at BT-High conditions. From 14 days to slaughter age, BT had no effect on broiler weight. ESD3-18°C chicks were heavier than ESD14-14°C chicks up to 28 days. The PepT1 and SGLT1 expression levels were significantly higher in ESD3-18°C chicks than ESD14-14°C on the day of hatch. There was significant egg storage by BT interaction for PepT1 and SGLT1 transporters at day 14. ESD14-14°C chicks had significantly higher expression of PepT1 and SGLT1 at BT-Low than those at BT-Cont. ESD14-14°C chicks upregulated PepT1 gene expression 1.15 and 1.57-fold at BT-High and BT-Low, respectively, compared with BT-Cont, whereas PepT1 expression was downregulated 0.67 and 0.62-fold in ESD3-18°C chicks at BT-High and BT-Low. These results indicated that pre-incubation egg storage conditions and BTs affected intestine morphology and PepT1 and SGLT1 nutrient transporters expression in broiler chicks.

  17. 75 FR 13294 - National Boating Safety Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ... the strategic planning process and any new issues or factors that could impact, or contribute to, the...) Recreational Boating Safety Strategic Planning Subcommittee meeting. Saturday, April 17, 2010: (12) Recreational Boating Safety Strategic Planning Subcommittee meeting (Cont.). (13) Prevention through People...

  18. Some characteristics of optokinetic eye-movement patterns : a comparative study.

    DOT National Transportation Integrated Search

    1970-07-01

    Long-associated with transportation ('railroad nystagmus'), optokinetic (OPK) nystagmus is an eye-movement reaction which occurs when a series of moving objects crosses the visual field or when an observer moves past a series of objects. Similar cont...

  19. Effects of climate change on croplands

    EPA Science Inventory

    This talk will describe likely changes in temperature and precipitation expected in the northwestern US with global climate change, and their potential impacts on Oregon croplands. The focus will be on the effects of temperature and carbon dioxide on crop productivity, weed cont...

  20. Technical memo : project 0-6132 (task 6).

    DOT National Transportation Integrated Search

    2010-04-01

    The attached memo presents construction information on the test sections placed by Madden Construction on US 59 on March 26th 2010. The memo includes details of the mix design, shows photographs of the construction sequence, lab test data on the Cont...

  1. The Private Military Industry: Economic Analysis, Uses & Considerations

    DTIC Science & Technology

    2007-03-01

    Intelligence US (cont.) Flour International SAIC Pacific Architects and Engineers Ibis Tek MVM Ibis Tek Samson Int’l Parsons ICI, Oregon New...Vinnell Meyer and Associates Prasons Parsons Worldwide Security MVM Protective Operation Corporate Training Raytheon New Bridge Strategies

  2. INORGANIC CHEMICAL CHARACTERIZATION OF WATER TREATMENT PLANT RESIDUALS

    EPA Science Inventory

    The study obtained field data on the inorganic contaminants and constituents in residuals produced by Water Treatment Plants (WTPs). Eight WTPs were studied based on treatment technology, contamination or suspected contamination of raw water, and efficiency in the removal of cont...

  3. Comparison of roadway roughness derived from LIDAR and SFM 3D point clouds.

    DOT National Transportation Integrated Search

    2015-10-01

    This report describes a short-term study undertaken to investigate the potential for using dense three-dimensional (3D) point : clouds generated from light detection and ranging (LIDAR) and photogrammetry to assess roadway roughness. Spatially : cont...

  4. Disk Operating System User's Guide

    DOT National Transportation Integrated Search

    1972-05-01

    This document serves the purpose of bringing together in one place most of the information a user needs to use the DDP-516 Disk Operating System, (DOS). DOS is a core resident, one user, console-oriented operating system which allows the user to cont...

  5. Glass Fiber Reinforced Polymer Dowel Bar Evaluation

    DOT National Transportation Integrated Search

    2012-09-01

    Glass Fiber Reinforced Polymer (GFRP) dowel bars were installed on one new construction project and two dowel bar : retrofit projects to evaluate the performance of this type of dowel bar in comparison to steel dowel bars installed on the same : cont...

  6. Under-reporting bipolar disorder in large-scale epidemiologic studies.

    PubMed

    Karam, Elie G; Sampson, Nancy; Itani, Lynn; Andrade, Laura Helena; Borges, Guilherme; Chiu, Wai Tat; Florescu, Silvia; Horiguchi, Itsuko; Zarkov, Zahari; Akiskal, Hagop

    2014-04-01

    To investigate if the prevalence of bipolar disorder in epidemiologic studies is an underestimate, as suggested by clinical studies. We analyzed data from 8 countries that participated in the World Mental Health Survey Initiative (n=47,552). We identified 6.8% and 18.9% of the sample who we think were screened out inappropriately (SCI) from the euphoric and irritable bipolar sections respectively. We compared them to those who were allowed to continue the section (CONT, 2.6% of the sample for euphoric; 1.0% for irritable) and to the reference group (REF, 69.5% of the sample). The SCI group had consistently higher rates of major depression (29.1% vs. 6.4%), earlier age of onset (24.3y vs. 32.4y), more suicide attempts (13.3% vs. 5.9%), and more episodes (4.2 vs. 2.7) than the REF for the euphoric group. Similar findings exist for the irritable group. Also, comorbidity with anxiety, disruptive behavior disorders and substance use were much higher than the REF. As with all epidemiologic studies, recall bias cannot be ruled out. The findings above suggest that a number of the SCI subjects belong to the bipolar group. A revision of instruments used in epidemiologic research will probably prove what clinical studies have been showing that bipolar disorder is more common than has been reported. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. INFLUENCE OF TOBACCO, ALCOHOL AND DIABETES ON THE COLLAGEN OF CREMASTER MUSCLE IN PATIENTS WITH INGUINAL HERNIAS.

    PubMed

    Módena, Sérgio Ferreira; Caldeira, Eduardo José; Peres, Marco Antonio O; Andreollo, Nelson Adami

    2016-01-01

    New findings point out that the mechanism of formation of the hernias can be related to the collagenous tissues, under activity of aggressive agents such as the tobacco, alcohol and diabetes. To analyze the collagen present in the cremaster muscle in patients with inguinal hernias, focusing the effect of tobacco, alcohol, and diabetes. Fifteen patients with inguinal hernia divided in three groups were studied: group I (n=5) was control; group II (n=5) were smokers and/or drinkers; and group III (n=5) had diabetes mellitus. All subjects were underwent to surgical repair of the inguinal hernias obeying the same pre, intra and postoperative conditions. During surgery, samples of the cremaster muscle were collected for analysis in polarized light microscopy, collagen morphometry and protein. The area occupied by the connective tissue was higher in groups II and III (p<0.05). The collagen tissue occupied the majority of the samples analyzed in comparison to the area occupied by muscle cells. The content of total protein was higher in groups II and III compared to the control group (p<0.05). The tobacco, alcohol and diabetes cause a remodel the cremaster muscle, leading to a loss of support or structural change in this region, which may enhance the occurrences and damage related to inguinal hernias. Estudos recentes sinalizam que o mecanismo de formação das hérnias pode estar relacionado aos tecidos colagenosos, sob a ação de agentes agressores como o tabaco, o álcool e o diabete. Avaliar o colágeno presente no músculo cremaster em pacientes com hérnias inguinais enfocando o efeito do tabaco, álcool e diabete. Foram estudados 15 pacientes com hérnias inguinais divididos em: grupo I (n=5) controles; grupo II (n=5) indivíduos fumantes e/ou etilistas; e grupo III (n=5) indivíduos que apresentavam diabete melito. Todos foram submetidos à correção cirúrgica das hérnias inguinais obedecendo às mesmas condições pré, intra e pós-operatórias. Durante o procedimento cirúrgico, amostras do músculo cremaster foram coletadas para análises em microscopia de luz polarizada, morfometria do colágeno e de proteínas. A área ocupada por tecido conjuntivo foi maior nos grupos II e III (p<0,05). O tecido colágeno ocupou a maior parte das amostras analisadas, em comparação à área ocupada pelas células musculares. O conteúdo de proteínas totais foi maior nos grupos II e III, quando comparado com o grupo controle (p<0,05). O tabaco, o álcool e o diabete ocasionam remodelação no músculo cremaster, levando à perda de suporte ou alteração estrutural nesta região, podendo intensificar as ocorrências e os danos relacionados às hérnias inguinais.

  8. AN ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) TESTING OF FOUR MERCURY EMISSION SAMPLING SYSTEMS

    EPA Science Inventory

    CEMs - Tekran Instrument Corp. Series 3300 and Thermo Electron's Mercury Freedom System Continuous Emission Monitors (CEMs) for mercury are designed to determine total and/or chemically speciated vapor-phase mercury in combustion emissions. Performance for mercury CEMs are cont...

  9. The role of the states in a federal climate program : issues and options

    DOT National Transportation Integrated Search

    2009-11-01

    This paper provides an overview of some of the key isuses regarding statefederal roles in a federal climate program and identifies four possible mechanisms that have been suggested for allowing states to set more stringent reduction targets. *Cont...

  10. Methanol as an Automotive Fuel : With Special Emphasis on Methanol-Gasoline Blends

    DOT National Transportation Integrated Search

    1977-04-01

    This report reviews the available information on methanol as related to its potential use as an automotive fuel. Information gaps critical to assessment and future decisions are delineated and suggestions made for necessary R&D efforts. In this conte...

  11. Solar production of industrial process steam ranging in temperature from 300/sup 0/F to 550/sup 0/F (Phase I). Volume 3. Appendices (cont). Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1979-06-30

    The following appendices are included: (1) instruments, (2) electrical specifications, (3) protective coverings, (4) welding requirements, (5) engineering specifications, and (6) administrative. (MOW)

  12. Quantification of Soil Redoximorphic Features by Standardized Color Identification

    USDA-ARS?s Scientific Manuscript database

    Photography has been a welcome tool in assisting to document and convey qualitative soil information. Greater availability of digital cameras with increased information storage capabilities has promoted novel uses of this technology in investigations of water movement patterns, organic matter conte...

  13. Variation for seed phytosterols in sunflower germplasm

    USDA-ARS?s Scientific Manuscript database

    Sunflower (Helianthus annuus L.) seeds and oils are rich sources of phytosterols, which are important compounds for human nutrition. There is limited information on variability for seed phytosterols in sunflower germplasm. The objective of the present research was to evaluate kernel phytosterol cont...

  14. Methods for assessing infestations of sunflower stem weevil (Coleoptera: Curculionidae) in sunflower stems

    USDA-ARS?s Scientific Manuscript database

    The sunflower stem weevil, Cylindrocopturus adspersus LeConte (Coleoptera: Curculionidae), reduces sunflower, Helianthus annuus L. (Asteraceae), yields by spreading pathogens, damaging vascular tissues, and promoting lodging of sunflower plants. To assess weevil populations for host plant resistanc...

  15. North Dakota Sunflower Insect Pest Survey, 2006-2008

    USDA-ARS?s Scientific Manuscript database

    The major insect pest species that cause economic losses to sunflower producers in North Dakota are banded sunflower moth (Cochylis hospes Walsingham), red sunflower seed weevil (Smicronyx fulvus Le Conte), and sunflower midge (Contarinia schulzi Gagne). New emerging insect pests include lygus bugs ...

  16. 2009 Sunflower Insect Pest Problems and Insecticide Update

    USDA-ARS?s Scientific Manuscript database

    Sunflowers (Helianthus annuus L.) are native to North America and a number of insect pests cause economic losses to sunflower production. Head-infesting insects include the red sunflower seed weevil, Smicronyx fulvus LeConte, banded sunflower moth, Cochylis hospes Walsingham, sunflower moth, Homoeos...

  17. Impacts of changes in ship design on transportation infrastructure and operations

    DOT National Transportation Integrated Search

    1998-02-01

    This report presented the input received by the U.S. Department of Transportation at four regional meetings addressing the question of how the growth in worldwide containerized trade and the expected growth in volumes of freight handled by major cont...

  18. Walker's Eleodes (Coleoptera: Tenebrionidae)

    USDA-ARS?s Scientific Manuscript database

    The type specimens of five species of Eleodes described by Francis Walker were studied in order to establish their true identity. The synonymy of Eleodes convexicollis Walker and Eleodes conjunctus Walker with E. obscurus (Say); that of Eleodes latiusculus Walker with E. humeralis LeConte; and that ...

  19. 75 FR 6398 - Ocean Transportation Intermediary License Applicants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... Forwarder Transportation Intermediary Applicants Best Way Logistics Corp., 901 SW. 98th Terrace, Pembroke..., Officers, Alessandro E. Bernardini, Sales Manager, (Qualifying Individual), Glenda Valdez, President... Intermediary Applicants (Cont'd): Vortex Worldwide Logistics Corp., 10125 NW. 116th Way, 10, Miami, FL 33178...

  20. A review of stormwater management in karst

    USDA-ARS?s Scientific Manuscript database

    Stormwater management can be a challenge in any environment, but it is especially difficult in karst terrain. The characteristic dissolution of bedrock creates depressions in topography as well as voids in the subsurface, resulting in problems such as collapse sinkhole development, groundwater cont...

  1. Aviation Behavioral Technology Program: Cockpit Human Factors Research Plan

    DOT National Transportation Integrated Search

    1985-01-15

    The safety, reliability, and efficiency of the National Airspace System depend upon the men and women who operate and use it. Aviation human factors research is the study of how these people function in the performance of their jobs as pilots, cont...

  2. Development of a short course in transportation planning for electronic delivery to DOTD.

    DOT National Transportation Integrated Search

    2000-12-01

    This report describes the preparation, delivery, and evaluation of a short course developed for delivery through compressed video to remote sites. The course covered basics of travel demand models and involved approximately 28 hours of classroom cont...

  3. System integration case study : FAST-TRAC : preliminary IV deliverable : #2-systems integration case study

    DOT National Transportation Integrated Search

    1999-02-12

    This report focuses on the system integration aspect of the Transportation Information Management System (TIMS), a component of the FAST-TRAC project. The TIMS functions as the center of a communications network which integrates advanced traffic cont...

  4. Leaf anthracnose, a new disease of swallow-worts from Russia

    USDA-ARS?s Scientific Manuscript database

    Black swallow-wort Vincetoxicum nigrum (L.) Moench (synonym=Cynanchum louiseae Kartesz & Gandhi) and pale swallow-wort Vincetoxicum rossicum (Kleopow) Borhidi (synonym=Cynanchum rossicum (Kleopow) Borhidi) are invasive plants belonging to the family Apocynaceae and are the targets of biological cont...

  5. TRIIODOTHYRONINE INCREASES MYOCARDIAL FUNCTION AND PYRUVATE ENTRY INTO THE CITRIC ACID CYCLE AFTER REPERFUSION IN A MODEL OF INFANT CARDIOPULMONARY BYPASS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olson, Aaron; Bouchard, Bertrand; Ning, Xue-Han

    We utilized a translational model of infant CPB to test the hypothesis that T3 modulates pyruvate entry into the citric acid cycle (CAC) thereby providing the energy support for improved cardiac function after ischemia-reperfusion. Methods and Results: Neonatal piglets received intracoronary [2-13Carbon(13C)]-pyruvate for 40 minutes (8 mM) during control aerobic conditions (Cont) or immediately after reperfusion (IR) from global hypothermic ischemia. A third group (IR-Tr) received T3 (1.2 ug/kg) during reperfusion. We assessed absolute CAC intermediate levels (aCAC) and flux parameters into the CAC through oxidative pyruvate decarboxylation (PDC ) and anaplerotic carboxylation (PC; ) using 13C-labeled pyruvate and isotopomermore » analysis by gas and liquid chromatography-mass spectrometry and 13C NMR. Neither IR nor IR-Tr modified aCAC. However, compared to IR, T3 (group IR-Tr) increased cardiac power and oxygen consumption after CPB while elevating both PDC and PC (~ four-fold). T3 inhibited IR induced reductions in CAC intermediate molar percent enrichment (MPE) and oxaloacetate(citrate)/malate MPE ratio; an index of aspartate entry into the CAC. Conclusions: T3 markedly enhances PC and PDC thereby providing substrate for elevated cardiac function and work after reperfusion. The increases in pyruvate flux occur with preservation of the CAC intermediate pool. Additionally, T3 inhibition of reductions in CAC intermediate MPEs indicates that T3 reduces the reliance on amino acids (AA) for anaplerosis after reperfusion. Thus, AA should be more available for other functions such as protein synthesis.« less

  6. Dietary flax seed oil and/or Vitamin E improve sperm parameters of cloned goats following freezing-thawing.

    PubMed

    Kargar, Rohollah; Forouzanfar, Mohsen; Ghalamkari, Gholamreza; Nasr Esfahani, Mohammad Hossein

    2017-02-01

    Semen cryopreservation is affected by individual differences and use of clones animal from the same source is the main tool to eliminate genetic variation. Among many nutrients that are necessary for fertility, essential fatty acids and antioxidants are vital for production of healthy sperm by improving sperm membrane integrity and protecting sperm from oxidative stress. The goal of the current study was to investigate whether a flax seed oil or/and Vitamin E dietary supplementation could improve semen quality of cloned bucks following semen cryopreservation. Accordingly, eight adult cloned Bakhtiari bucks were divided randomly into four groups. Bucks were offered a base diet of hay and concentrate. The concentrate was enriched with flax seed oil, 30 gr/kg body weight/day (OIL), Vitamin E (VIT), 3 gr/kg body weight/day, or combined flax seed oil and the vitamin E (OIL-VIT). The concentrate with no supplements was considered as control group (CONT). Both flax seed oil and Vitamin E supplements were added to the total diet. The bucks were fed with their corresponding diets for a total of 9 weeks while sperm collection was carried out within 10-14 weeks. Ejaculates were diluted with Andromed ® and were frozen in liquid nitrogen. Sperm parameters and reactive oxygen species (ROS) contents were evaluated following freezing/thawing. According to the results of our study, dietary supplementation with flax seed oil, or/and Vitamin E can improve sperm motility, vitality and number of sperm with intact plasma membrane following freezing-thawing. But the degree of improvement in these parameters was significantly higher when Flax seed oil and vitamin E were co-supplemented. Copyright © 2016. Published by Elsevier Inc.

  7. Time of planting and choice of maize hybrids in controlling WCR (Diabrotica virgifera virgifera Le Conte) in Serbia and Montenegro.

    PubMed

    Baca, F; Videnovic, Z; Erski, P; Stankovic, R; Dobrikovic, Danica

    2003-01-01

    Effects of the length of growing season of maize hybrids (FAO maturity groups 400, 500, 600 and 700) and planting dates on the maize crop, as an attractive supplemental feeding for western corn rootworm (WCR) beetles and larval survival, were observed in two locations of South Banat, during a three-year (1997-1999) and a two-year period (2001 and 2002). The feeding attraction of the maize crop for WCR beetles and survival of larvae were evaluated in dependency of the variable "plant lodging". The following results were obtained: First location: A. Plant lodging over time of planting and applied insecticides. 1. Early planting: 44.2%, 77.6%, and 76.7% for FAO 400, 500 and 600, respectively. 2. Late planting: 4.7%, 14.9%, and 7.9% for FAO 400, 500 and 600, respectively. B. Plant lodging over time of planting and cropping practices: 1. Early planting without insecticide application 72.2%, and with insecticide application 7.3%. The efficacy of application of insecticide carbofurane (Furadan 350 FS, dosage 4.0 liter/ha) in larval control was 89.9%. 2. Late planting without insecticide application, plant lodging was 47.7%, and with insecticide application 8.1%. The efficacy of application of insecticide carbofurane (Furadan 350 FS, dosage 4.0 l/ha-1) in larval control was 83.0%. Early planting resulted in greater survival of larvae; hence plant lodging was 10 times greater in early than in late planting. The percentage of lodged plants indicates that the maize crop in late planting was more attractive to imagoes. Therefore, more lodged plants were observed in the treatment where late planting preceded. Second location: Plant lodging as dependent on "treatments" 1. Regular plantings: 90.7% in untreated control and 76.2% in insecticide treated variant. The efficacy of insecticide application in control of high larval population was 16.0%. 2. Replanting date: 12.2% in untreated and 4.4% in treated variant. The efficacy of insecticide in control of low larval population increased from 16.0 to 63.9%. To successfully decrease the size and intensity of attacks of the Diabrotica v. virgifera population under conditions of applying insecticides or not, it is necessary to use maize hybrids of the earliest possible maturity group and to plant the seed on the earliest date possible in the first year of growing maize, if maize is to be followed by maize in the next year.

  8. Influence of elevation on bark beetle (Coleoptera: Curculionidae, Scolytinae) community structure and flight periodicity in ponderosa pine forests of Arizona.

    PubMed

    Williams, Kelly K; McMillin, Joel D; DeGomez, Tom E; Clancy, Karen M; Miller, Andy

    2008-02-01

    We examined abundance and flight periodicity of five Ips and six Dendroctonus species (Coleoptera: Curculionidae, Scolytinae) among three different elevation bands in ponderosa pine (Pinus ponderosa Douglas ex. Lawson) forests of northcentral Arizona. Bark beetle populations were monitored at 10 sites in each of three elevation bands (low: 1,600-1,736 m; middle: 2,058-2,230 m; high: 2,505-2,651 m) for 3 yr (2004-2006) using pheromone-baited Lindgren funnel traps. Trap contents were collected weekly from March to December. We also studied temperature differences among the elevation bands and what role this may play in beetle flight behavior. Bark beetles, regardless of species, showed no consistent elevational trend in abundance among the three bands. The higher abundances of Ips lecontei Swaine, I. calligraphus ponderosae Swaine, Dendroctonus frontalis Zimmerman, and D. brevicomis LeConte at low and middle elevations offset the greater abundance of I. knausi Swaine, D. adjunctus Blandford, D. approximatus Dietz, and D. valens LeConte at high elevations. I. pini (Say) and I. latidens LeConte were found in similar numbers across the three bands. Flight periodicity of several species varied among elevation bands. In general, the flight period shortened as elevation increased; flight initiated later and terminated earlier in the year. The timing, number, and magnitude of peaks in flight activity also varied among the elevation bands. These results suggest that abundance and flight seasonality of several bark beetles are related to elevation and the associated temperature differences. The implications of these results are discussed in relation to bark beetle management and population dynamics.

  9. Cold water immersion recovery following intermittent-sprint exercise in the heat.

    PubMed

    Pointon, Monique; Duffield, Rob; Cannon, Jack; Marino, Frank E

    2012-07-01

    This study examined the effects of cold water immersion (CWI) on recovery of neuromuscular function following simulated team-sport exercise in the heat. Ten male team-sport athletes performed two sessions of a 2 × 30-min intermittent-sprint exercise (ISE) in 32°C and 52% humidity, followed by a 20-min CWI intervention or passive recovery (CONT) in a randomized, crossover design. The ISE involved a 15-m sprint every minute separated by bouts of hard running, jogging and walking. Voluntary and evoked neuromuscular function, ratings of perceived muscle soreness (MS) and blood markers for muscle damage were measured pre- and post-exercise, immediately post-recovery, 2-h and 24-h post-recovery. Measures of core temperature (Tcore), heart rate (HR), capillary blood and perceptions of exertion, thermal strain and thirst were also recorded at the aforementioned time points. Post-exercise maximal voluntary contraction (MVC) and activation (VA) were reduced in both conditions and remained below pre-exercise values for the 24-h recovery (P < 0.05). Increased blood markers of muscle damage were observed post-exercise in both conditions and remained elevated for the 24-h recovery period (P < 0.05). Comparative to CONT, the post-recovery rate of reduction in Tcore, HR and MS was enhanced with CWI whilst increasing MVC and VA (P < 0.05). In contrast, 24-h post-recovery MVC and activation were significantly higher in CONT compared to CWI (P = 0.05). Following exercise in the heat, CWI accelerated the reduction in thermal and cardiovascular load, and improved MVC alongside increased central activation immediately and 2-h post-recovery. However, despite improved acute recovery CWI resulted in an attenuated MVC 24-h post-recovery.

  10. Application of the MAFFT sequence alignment program to large data—reexamination of the usefulness of chained guide trees

    PubMed Central

    Yamada, Kazunori D.; Tomii, Kentaro; Katoh, Kazutaka

    2016-01-01

    Motivation: Large multiple sequence alignments (MSAs), consisting of thousands of sequences, are becoming more and more common, due to advances in sequencing technologies. The MAFFT MSA program has several options for building large MSAs, but their performances have not been sufficiently assessed yet, because realistic benchmarking of large MSAs has been difficult. Recently, such assessments have been made possible through the HomFam and ContTest benchmark protein datasets. Along with the development of these datasets, an interesting theory was proposed: chained guide trees increase the accuracy of MSAs of structurally conserved regions. This theory challenges the basis of progressive alignment methods and needs to be examined by being compared with other known methods including computationally intensive ones. Results: We used HomFam, ContTest and OXFam (an extended version of OXBench) to evaluate several methods enabled in MAFFT: (1) a progressive method with approximate guide trees, (2) a progressive method with chained guide trees, (3) a combination of an iterative refinement method and a progressive method and (4) a less approximate progressive method that uses a rigorous guide tree and consistency score. Other programs, Clustal Omega and UPP, available for large MSAs, were also included into the comparison. The effect of method 2 (chained guide trees) was positive in ContTest but negative in HomFam and OXFam. Methods 3 and 4 increased the benchmark scores more consistently than method 2 for the three datasets, suggesting that they are safer to use. Availability and Implementation: http://mafft.cbrc.jp/alignment/software/ Contact: katoh@ifrec.osaka-u.ac.jp Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27378296

  11. Glutamate supply positively affects serum cholesterol concentrations without increases in total protein and urea around the onset of puberty in goats.

    PubMed

    Meza-Herrera, C A; Calderón-Leyva, G; Soto-Sanchez, M J; Serradilla, J M; García-Martinez, A; Mellado, M; Veliz-Deras, F G

    2014-06-30

    Different neurotransmitter and neuromodulatory systems regulate synthesis and secretion of GnRH. Whereas the endocrine and neural systems are activated in response to the metabolic status and the circulating levels of specific blood metabolites, glutamate receptors have been reported at hepatic level. This study evaluated the possible effect of glutamate supplementation upon changes in serum concentrations across time for total protein (TP), urea (UR) and cholesterol (CL) around the onset of puberty in goats. Prepuberal female goats (n=18) were randomly assigned to: (1) excitatory amino acids group, GLUT, n=10; 16.52±1.04kg live weight (LW), 3.4±0.12 body condition score (BCS) receiving an i.v. infusion of 7mgkg(-1) LW of l-glutamate, and (2) Control group, CONT, n=8; 16.1±1.04kg LW, 3.1±0.12 BCS. General averages for LW (23.2±0.72kg), BCS (3.37±0.10 units), serum TP (65.28±2.46mgdL(-1)), UR (23.42±0.95mgdL(-1)), CL (77.89±1.10mgdL(-1)) as well as the serum levels for TP and UR across time did not differ (P>0.05) between treatments. However, while GLUT positively affected (P<0.05) both the onset (207±9 vs. 225±12 d) and the percentage (70 vs. 25%) of females showing puberty, a treatment×time interaction effect (P<0.05) was observed in the GLUT group, with increases in serum cholesterol, coincident with the onset of puberty. Therefore, in peripuberal glutamate supplemented goats, serum cholesterol profile could act as a metabolic modulator for the establishment of puberty, denoting also a potential role of glutamate as modulator of lipid metabolism. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. 75 FR 80515 - National Boating Safety Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-22

    ... 15, 2011, from 9 a.m. to 12 p.m., and the Recreational Boating Safety Strategic Planning Subcommittee... Boating Safety Strategic Planning Subcommittee meeting to discuss current status of the strategic planning... Boating Safety Strategic Planning Subcommittee meeting (Cont.). (7) Receipt and discussion of the...

  13. Toll facilities in the United States : bridges, roads, tunnels, ferries

    DOT National Transportation Integrated Search

    1995-02-01

    This report contains selected information on toll facilities in the United States. The information is based on a survey of facilities in operation, financed, or under construction as of January 1, 1995, and is presented in four tables. Table T-1 cont...

  14. 50 CFR 32.48 - New Hampshire.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... the shoreline of Great Bay. D. Sport Fishing. [Reserved] Silvio O. Conte National Fish and Wildlife...'s or OHV's). B. Upland Game Hunting. We allow hunting of coyote, fox, raccoon, woodchuck, red.... Sport Fishing. [Reserved] Umbagog National Wildlife Refuge A. Migratory Game Bird Hunting. We allow...

  15. 50 CFR 32.48 - New Hampshire.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the shoreline of Great Bay. D. Sport Fishing. [Reserved] Silvio O. Conte National Fish and Wildlife...'s or OHV's). B. Upland Game Hunting. We allow hunting of coyote, fox, raccoon, woodchuck, red.... Sport Fishing. [Reserved] Umbagog National Wildlife Refuge A. Migratory Game Bird Hunting. We allow...

  16. 50 CFR 32.48 - New Hampshire.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... the shoreline of Great Bay. D. Sport Fishing. [Reserved] Silvio O. Conte National Fish and Wildlife...'s or OHV's). B. Upland Game Hunting. We allow hunting of coyote, fox, raccoon, woodchuck, red.... Sport Fishing. [Reserved] Umbagog National Wildlife Refuge A. Migratory Game Bird Hunting. We allow...

  17. Representative Elementary Area Determinations through Digital Photography, Image Analysis, and Soil Color

    USDA-ARS?s Scientific Manuscript database

    Photography has been a welcome tool in assisting to document and convey qualitative soil information. Greater availability of digital cameras with increased information storage capabilities has promoted novel uses of this technology in investigations of water movement patterns, organic matter conte...

  18. CHARACTERIZING AND PROVIDING ADEQUATE PROTECTION FOR SUSCEPTIBLE SUBPOPULATIONS: SUSCEPTIBLE POPULATIONS: SUSCEPTIBILITY ASSOCIATED WITH THE AGED

    EPA Science Inventory

    SUMMARY: An important Agency mandate is to identify subpopulations particularly susceptible to adverse effects associated with exposure to environmental contaminants. For example, a critical public health question is the extent to which exposure to environmental contaminants cont...

  19. Feral biofuel crop effects in constructed wet prairie and oak savannah communities

    EPA Science Inventory

    We examined the potential effects of feral biofuel crop escapes on constructed plant communities growing in outdoor mesocosms. Mesocosms containing wet prairie or oak savannah communities were exposed to two temperature levels (ambient and elevated) and two moisture levels (cont...

  20. Phenotypic changes in laboratory-reared colonies of the maize herbivore, Diabrotica virgifera virgifera

    USDA-ARS?s Scientific Manuscript database

    The North American and European maize pest Diabrotica virgifera virgifera LeConte (Coleoptera: Chrysomelidae) was used to assess whether environmental conditions of the natal field, subsequent laboratory rearing, or genetic population characteristics affect phenotypic traits of fitness, activity, or...

  1. Utilizing micro simulation to evaluate the safety and efficiency of the expressway system.

    DOT National Transportation Integrated Search

    2016-08-01

    Expressways play a vital role in serving mega-cities, and the safety of expressways : is extremely important. In order to explore the crash mechanisms of expressways, : previous studies have mainly utilized average daily traffic (ADT) as a major cont...

  2. Contributions of pyrogenic materials on the accumulation of soil organic matter

    USDA-ARS?s Scientific Manuscript database

    Soil amendment of charcoal co-product (HHVdb as high as coal) from thermochemical waste biomass-to-energy conversion (slow/fast pyrolysis and gasification) has received considerable interests for both contaminated and agricultural lands. Biochar amendment not only increases soil organic carbon cont...

  3. Part-time Labor, Work Rules, and Transit Costs

    DOT National Transportation Integrated Search

    1981-01-01

    This report examines two major issues: (1)the impact of labor union work rules : on bus transit operating costs and (2)the magnitude of cost savings that can be : expected from the use of part-time drivers. These issues are examined within : the cont...

  4. 78 FR 22517 - Endangered Species; File No. 16549

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-16

    ... the S.O. Conte Anadromous Fish Research Center, U.S. Geological Survey; Box 796, 1 Migratory Way... take shortnose sturgeon (Acipenser brevirostrum) for purposes of scientific research. ADDRESSES: The... a scientific research permit to take shortnose sturgeon had been submitted by the above-named...

  5. Latent carcinogenicity of early-life exposure to dichloroacetic acid in mice

    EPA Science Inventory

    AbstractEnvironmental exposures occurring early in life may have an important influence on cancer risk later in life. Here we investigated carryover effects of young-adult exposure to dichloroacetic acid (DCA), a small molecule analog of pyruvate and low-level environmental cont...

  6. Estimating wheat growth with radar vegetation indices

    USDA-ARS?s Scientific Manuscript database

    In this study, we computed the Radar Vegetation Index (RVI) using observations made with a ground based multi-frequency polarimetric scatterometer system over an entire wheat growth period. The temporal variations of the backscattering coefficients for L-, C-, and X-band, RVI, vegetation water conte...

  7. Immune responses of poultry to newcastle disease virus

    USDA-ARS?s Scientific Manuscript database

    Newcastle disease (ND) remains a constant threat to poultry producers worldwide, in spite of the availability and global employment of ND vaccinations since the 1950s. Strains of Newcastle disease virus (NDV) belong to the order Mononegavirales, family Paramyxoviridae, and genus Avulavirus, are cont...

  8. Exercise, Sports and Tourette Syndrome

    MedlinePlus

    ... Tourette Brain Bank Español ¿Qué es el síndrome de Tourette? Síndrome de Tourette: preguntas frecuentes Viviendo con Tourette Educación Artículos Médicos Listas de médicos y terapeutas Contáctenos Contact Us About Tourette ...

  9. Department of the Navy Justification of Estimates for Fiscal Years 1988 and 1989 Submitted to Congress January 1987. Operation & Maintenance, Navy. Book 1. Budget Activity 1. Strategic Forces Budget Activity 2. General Purpose Forces Budget Activity 4. Airlift and Sealift.

    DTIC Science & Technology

    1987-01-01

    166 174 170 167 Config Change Rqsts 45 54 53 52 Config Audits 20 26 26 25 Manual Change Rqsts 516 500 489 477 Work Years 91 90 90 90 7) Noise Reduction... manual methods. 771 ’ 1 1-50 3442f/7 Activity Group: Space Systems Operations (cont’d) AMOUNT C. Other Program Growth in FY 1989 (878) 1) Space...P+WS htp ~ h Na vy lr,(j Ma? itf’ to a nri rt. r 1’r f 1, Pri y t, i lu, iwe, a t ion, t a t H % ;, i rndi t 04 l I r k 4, PMfi , . j(I l j ,’Ř

  10. Comparative assessment of four Steinernematidae and three Heterorhabditidae species for infectivity of larval Diabrotica virgifera virgifera

    USDA-ARS?s Scientific Manuscript database

    Larval Diabrotica virgifera virgifera LeConte were exposed to seven different entomopathogenic nematode species to test their potential infectivity in a laboratory setting. Known D. virgifera infecting nematode species Heterorhabditis bacteriophora Poinar, H. megidis Poinar, Jackson & Klein, Steiner...

  11. Reconstructing daily clear-sky land surface temperature for cloudy regions from MODIS data

    USDA-ARS?s Scientific Manuscript database

    Land surface temperature (LST) is a critical parameter in environmental studies and resource management. The MODIS LST data product has been widely used in various studies, such as drought monitoring, evapotranspiration mapping, soil moisture estimation and forest fire detection. However, cloud cont...

  12. U.S. EPA, Pesticide Product Label, , 05/08/1989

    EPA Pesticide Factsheets

    2011-04-21

    ... "'hare po •• 1bl •. ... ":" •• S 5?:-!:e":" n .. a=~. ;a:: .. r~~a .~~ ~. r, c~a:-g .. ra. ... Cont.et :rour !tate 'aatlelde or I:nel ron.ent.l Con:ro~ A9an:::T or Ha ...

  13. Comparison of two reference methods for detemining cotton fiber moisture

    USDA-ARS?s Scientific Manuscript database

    Moisture is an important quality and processing property for the cotton industry. The standard reference method for determining the moisture content in cotton fiber is the ASTM oven method (gravimetric weight loss). Several concerns have expressed on its ability to measure the actual moisture cont...

  14. REMOVING ORGANIC CONTAMINANTS OF REGULATORY INTEREST WITH MEMBRANE PROCESSES: USEPA'S SCREENING STUDIES

    EPA Science Inventory

    The 1996 amendments to the Safe Drinking Water Act require the US Environmental Protection Agency (USEPA) to establish a list of unregulated microbiological and chemical contaminants to aid in priority-setting for the Agency's drinking water program. This list, known as the Cont...

  15. DEVELOPMENT OF A MODEL THAT CONTAINS BOTH MULTIPOLE MOMENTS AND GAUSSIANS FOR THE CALCULATION OF MOLECULAR ELECTROSTATIC POTENTIALS

    EPA Science Inventory

    The electrostatic interaction is a critical component of intermolecular interactions in biological processes. Rapid methods for the computation and characterization of the molecular electrostatic potential (MEP) that segment the molecular charge distribution and replace this cont...

  16. ULTRAPETALA trxG genes interact with KANADI transcription factor genes to regulate Aradopsis Gynoecium patterning

    USDA-ARS?s Scientific Manuscript database

    Organ formation relies upon precise patterns of gene expression that are under tight spatial and temporal regulation. Transcription patterns are specified by several cellular processes during development, including chromatin remodeling, but little is known about how chromatin remodeling factors cont...

  17. Non-constant thermal regimes enhance overwintering success and accelerate diapause development for Smicronyx fulvus (Coleoptera: Curculionidae)

    USDA-ARS?s Scientific Manuscript database

    Recent populations of the red sunflower seed weevil, Smicronyx fulvus LeConte (Coleoptera: Curculionidae) have been inconsistent or declining, particularly in North Dakota. Consequently, field and laboratory research on weevil biology, including development of resistant germplasm, have been limited....

  18. How C2 Goes Wrong (Briefing Chart)

    DTIC Science & Technology

    2014-06-01

    Guardian/Pix/pictures/2012/12/19/1355903591995/Hillsborough-disaster-010.jpg Cases (3): Disaster/Emergency Response (Cont.) Columbine High School ...r337173_1529332.jpg http://bossip.files.wordpress.com/2012/11/ massacre -e1352384704110.jpeg?w=625&h=389 The Punchline “What we’ve got here, is

  19. Ipsenol: An Aggregation Pheromone for Ips latidens (LeConte) (Coleoptera: Scolytidae)

    Treesearch

    Daniel R. Miller; John H. Borden; G.G.S. King; Keith N. Slessor

    1991-01-01

    Ipsenol was identified from the frass of male, but not female, Ips latidens from British Columbia, feeding in phloem tissue of lodgepole pine, Pinus contorta var. latifolia. The responses of I. latidens to sources of ipsenol and cis-verbenol were determined with multiple-...

  20. Abstracts in Journal of Animal Science

    USDA-ARS?s Scientific Manuscript database

    Journal of Animal Science (JAS) is the leading international journal for animal science research. The American Society of Animal Science publishes JAS to support its mission, “To discover, disseminate, and apply knowledge for sustainable use of animals for food and other human needs.” Thus, JAS cont...

  1. 100 years of the cullars rotation (c. 1911).

    USDA-ARS?s Scientific Manuscript database

    Alabama’s “Cullars Rotation” experiment (circa 1911) was placed on the National Register of Historical Places as the oldest, continuous, soil fertility experiment in the South in 2003. Along with its nearby predecessor on the National Register, “The Old Rotation” (circa 1896), these experiments cont...

  2. Monogalactosyldiacylglycerols as host recognition cues for western corn rootworm larvae (Coleoptera: Chrysomelidae)

    USDA-ARS?s Scientific Manuscript database

    Monogalactosyldiacylglycerol (MGDG) was identified as a host recognition cue for larvae of the western corn rootworm Diabrotica virgifera virgifera LeConte. An active glycolipid fraction obtained from an extract of germinating maize roots was isolated with thin layer chromatography using a bioassay-...

  3. Madison County energy conservation study : 2012-2013 survey of roadside vegetation.

    DOT National Transportation Integrated Search

    2014-02-01

    The current clear zone mowing frequency for I-10 in Madison County (FDOT Maintenance District 2) is 7 times per year. To conserve energy and reduce expenses associated with mowing, a pilot study was implemented in 2009, and continued in 2010-11 (Cont...

  4. Evaluation of several types of curing and protective materials for concrete : interim report part III : performance.

    DOT National Transportation Integrated Search

    1973-01-01

    Various curing and/or protective coatings were evaluated under three conditions: (1) accelerated laboratory freezing and thawing of specimens in 2 percent sodium chloride solution, (2) exposure in an outdoor area of slabs which were subjected to cont...

  5. Monte Carlo Simulation of Microscopic Stock Market Models

    NASA Astrophysics Data System (ADS)

    Stauffer, Dietrich

    Computer simulations with random numbers, that is, Monte Carlo methods, have been considerably applied in recent years to model the fluctuations of stock market or currency exchange rates. Here we concentrate on the percolation model of Cont and Bouchaud, to simulate, not to predict, the market behavior.

  6. Imagens do céu ontem e hoje - um multimídia interativo de astronomia e uma nova exposição no MAST

    NASA Astrophysics Data System (ADS)

    Caretta, C. A.; Lima, F. P.; Requeijo, F.; Vieira, G. G.; Alves, F.; Valente, M. E. A.; de Almeida, R.; de Garcia, G. C.; Quixadá, A. C.

    2003-08-01

    "Imagens do Céu Ontem e Hoje" é o título de uma nova exposição que está sendo inaugurada no Museu de Astronomia e Ciências Afins (MCT), que inclui experimentos interativos, maquetes, réplicas e 8 terminais de computador com um multimídia interativo sobre Astronomia para consulta dos visitantes. O multimídia apresenta um conteúdo bastante extenso, que engloba quase todos os temas em Astronomia, consistindo numa fonte de divulgação e pesquisa para um público que vai das crianças até estudantes universitários. O conteúdo está distribuído em mais de 500 páginas de texto divididas em 4 módulos: "O Universo", "Espectroscopia", "Telescópios" e "Observando o Céu". Cada módulo é subdividido em 5 seções, em média, cada uma iniciada por uma animação que ilustra os temas a serem abordados na seção. Ao final da animação, uma lista de temas é apresentada sob o título "Saiba Mais". Para exemplificar, o módulo "O Universo" contém as seguintes seções: "O Universo visto pelo homem", "Conhecendo o Sistema Solar", "Indo além do Sistema Solar", "Nossa Galáxia, a Via-Láctea" e "Indo mais além, a imensidão do Universo". A seção "Conhecendo o Sistema Solar", por sua vez, tem os seguintes temas: "A origem do Sistema Solar", "O Sol", "Os planetas", "Satélites, asteróides, cometas e outros bichos..." e "O Sistema Solar em números". Cada texto é repleto de imagens, quadros, desenhos, esquemas, etc, além de passatempos ao final de cada seção, incluindo jogos interativos, quadrinhos e curiosidades, que auxiliam o aprendizado de forma divertida. Apresentamos neste trabalho as idéias gerais que permearam a produção da exposição, e uma viagem pelo multimídia para exemplificar sua estrutura e conteúdo. O multimídia será posteriormente disponibilizado para o público externo pela página eletrônica do MAst e/ou por intermédio de uma publicação comercial.

  7. Temporal Geophysical Investigations of the FT-2-Plume at the Wurtsmith Air Force Base, Oscoda, Michigan

    EPA Science Inventory

    The decommissioned Wurtsmith Air Force Base former Fire Training Cell (FT-02) facility has been the focus of several geophysical investigations. After several decades of fire training exercises, significant amounts of hydrocarbons and some solvents seeped into the subsurface cont...

  8. TEMPORAL GEOPHYSICAL INVESTIGATIONS OF THE FT-2-PLUME AT THE WURTSMITH AIR FORCE BASE, OSCODA, MICHIGAN

    EPA Science Inventory

    The decommissioned Wurtsmith Air Force Base former Fire Training Cell (FT-02) facility has been the focus of several geophysical investigations. After several decades of fire training exercises, significant amounts of hydrocarbons and some solvents seeped into the Subsurface cont...

  9. Synthetic feeding stimulants enhance insecticide activity against western corn rootworm larvae, Diabrotica virgifera virgifera (Coleoptera: Chrysomelidae)

    USDA-ARS?s Scientific Manuscript database

    In behavioral bioassays, the addition of a synthetic feeding stimulant blend improved the efficacy of the insecticide thiamethoxam against neonate western corn rootworm, Diabrotica virgifera virgifera LeConte, larvae. In 4-h bioassays, the concentration of thiamethoxam required for 50% mortality (LC...

  10. Hydraulic Diagnostic Monitoring System.

    DTIC Science & Technology

    1981-03-02

    devices were utilized. In one pneumatic circuit, a temperature-compensated pressure switch performed as predicted over a broad tempera- ture range. In...installation ...... ................. 41 9 NADC 81073-60 ILLUSTRATIONS (Cont) Fig. No. Page 28 Temperature-compensated pressure switch .... ................. .42...29 Plot of pressure vs temperature for nitrogen .... ................ .. 43 30 Temperature-compensated pressure switch : diagrammatic circuit

  11. Haplotype analysis of global chili thrips (Schirtothrips dorsalis) populations using the metazoan barcode

    USDA-ARS?s Scientific Manuscript database

    Scirtothirps dorsalis is a globally invasive polyphagous crop pest infesting several major field and ornamental crops. Established in Florida since 2005, it had spread to Texas within one year. Establishing a putative source locality of the US population would help stakeholders target effective cont...

  12. Haplotype analysis of global chilli thrips (Scirtothrips dorsalis) populations using the metazoan barcode

    USDA-ARS?s Scientific Manuscript database

    Scirtothirps dorsalis is a globally invasive polyphagous crop pest infesting several major field and ornamental crops. Established in Florida since 2005, it had spread to Texas within one year. Establishing a putative source locality of the US population would help stakeholders target effective cont...

  13. Trap lure blend of pine volatiles and bark beetle pheromones for Monochamus spp. (Coleoptera: Cerambycidae) in pine forests of Canada and the United States.

    Treesearch

    Dan Miller; Kevin J. Dodds; Andy Eglitis; Chris Fettig; Richard W. Hofstetter; David W. Langor; Albert (Bud) Mayfield; A. Steven Munson; Therese M. Poland; Kenneth F. Raffa

    2013-01-01

    In 2007-2008, we examined the flight responses of Monochamus titillator (F.) complex [M. titillator, Monochamus carolinensis (Olivier), and any possible hybrids], Momonchamus scutellatus (Say), Monochamus clamator (LeConte), Monochamus obtusus Casey, and Monochamus...

  14. Badger (Taxidea taxus) disturbances increase soil heterogeneity in a degraded shrub-steppe ecosystem

    USDA-ARS?s Scientific Manuscript database

    In the western United States, overgrazing, weed invasion and wildfire have resulted in the conversion of shrub-steppe to annual grasslands, with substantial effects on ecosystem function. In these landscapes, badgers disturb large areas of soil while foraging for prey. Mounds created by badgers cont...

  15. Stridulatory mechanisms and sound production in Conotrachelus (Coleoptera: Curculionidae)

    Treesearch

    Lester P. Gibson

    1967-01-01

    The elytral stridulitra and the plectra on the sixth abdominal tergite are described and illustrated for both sexes of Conotrachelus naso LeConte, C. posticatus Boheman, and C. carinifer Casey, as is the stridulitrum of the male C. nenuphar (Herbst); the female of C. nenuphar has no...

  16. A Random Forest Approach to Predict the Spatial Distribution of Sediment Pollution in an Estuarine System

    EPA Science Inventory

    Modeling the magnitude and distribution of sediment-bound pollutants in estuaries is often limited by incomplete knowledge of the site and inadequate sample density. To address these modeling limitations, a decision-support tool framework was conceived that predicts sediment cont...

  17. Continuous nutrient administration decreases insulin sensitivity in neonatal pigs

    USDA-ARS?s Scientific Manuscript database

    We previously showed that chronic TPN compared to intermittent feeding of a formula results in hepatic insulin resistance and steatosis in neonatal pigs. We hypothesized that the route of feeding (IV vs enteral) rather than the nature of the diet (elemental vs polymeric) or the feeding regimen (cont...

  18. Genome sequence of the first coleopteran iflavirus isolated from western corn rootworm, Diabrotica virgifera virgifera LeConte

    USDA-ARS?s Scientific Manuscript database

    Western corn rootworm (WCR), Diabrotica virgifera virgifera, adults were collected from cornfields in the United States (Iowa, Arizona, Pennsylvania), and Europe (Hungary, Croatia, Austria). Total RNA was extracted from ~100 individuals from different locations, and putative viral RNA was isolated f...

  19. Relationships between Private Domestic Wells and Underground Storage Tanks: Evaluation of Mapping and Plume Transport Tool Implementations

    EPA Science Inventory

    Well water from private domestic wells (hereafter private wells) is often not tested as private owners are exempt from sampling requirements of the Safe Drinking Water Act. Numerous incidents of contamination of water in private wells have been reported, however. Potential cont...

  20. Chronic stress is associated with indicators of diet quality in habitual breakfast skippers

    USDA-ARS?s Scientific Manuscript database

    Background. Previous studies suggest that eating breakfast is associated with better diet quality, but reasons underlying this relationship are not clear. Objective. Our objective was to assess diet quality of women with established breakfast habits and determine if stress or cognitive function cont...

  1. Automation Applications in an Advance Air Traffic Management System : Volume IIB : Functional Analysis of Air Traffic Management (Cont'd)

    DOT National Transportation Integrated Search

    1974-08-01

    Volume 2 contains the analysis and description of air traffic management activities at three levels of detail - functions, subfunctions, and tasks. A total of 265 tasks are identified and described, and the flow of information inputs and outputs amon...

  2. Response of different white fir geographic provenances to Trichosporium symbioticum inoculation in California

    Treesearch

    William J. Otrosina; Stanley J. Zarnoch

    2012-01-01

    We inoculated the fir engraver (Scolytus ventralis LeConte) associated fungus Trichosporium symbioticum Wright onto 56 white fir (Abies concolor (Gordon & Glend.) Lindl. ex Hildebr.) trees planted in a common garden study near Camino, California, that represented five geographic provenances of this species....

  3. Residual efficacy of deltamethrin and ß-cyfluthrin against Trogoderma variabile and Trogoderma inclusum (Coleoptera: Dermestidae)

    USDA-ARS?s Scientific Manuscript database

    Trogroderma variabile Ballion, warehouse beetle, and Trogoderma inclusum LeConte, larger cabinet beetle, are dermestid pests of stored products. A series of laboratory bioassays were conducted to evaluate residual toxicity of the pyrethroids ß-cyfluthrin and deltamethrin, applied on a concrete surf...

  4. THE TOXOSTOMA THRASHERS OF CALIFORNIA: SPECIES AT RISK?

    Treesearch

    WILLIAM F. LAUDENSLAYER; A. SIDNEY ENGLAND; SAM FITTON; LARRY SASLAW

    1992-01-01

    Four of the 10 described species of Toxostoma thrasher breed in California-California thrasher (T. redivivum), Bendire's thrasher (T. bendirei), Crissal thrasher (T. crissale), and Le Conte's thrasher (T. fecontei). Urbanization, agricultural development, fire management, and livestock grazing are among the land uses that affect large tracts of the habitats...

  5. Vertical displacement of Ips Latidens and Ips Pini

    Treesearch

    Daniel R. Miller

    2000-01-01

    The effect of semiochemical interruptants was examined for Ips latidens (LeConte) and Ips pini (Say) using artificial trees (tall-traps) consisting of an array of seven Lindgren multiple-funnel traps suspended vertically on a rope ladder. S-(+)- Ipsdienol reduced the numbers of I. latidens captured in (±)-ipsenol...

  6. Field assessment of hybridization between Laricobius nigrinus and L. rubidus, predators of Adelgidae

    Treesearch

    Melissa J. Fischer; Nathan P. Havill; Carlyle C. Brewster; Gina A. Davis; Scott M. Salom; Loke T. Kok

    2015-01-01

    Two adelgid predators, Laricobius nigrinus Fender and Laricobius rubidus LeConte, were recently discovered to produce hybrid progeny in the eastern United States. L. rubidus is native to eastern North America where it feeds on pine bark adelgid (Pineus strobi Hartig) and L. nigrinus...

  7. 77 FR 21750 - Endangered Species; File Nos. 16549 and 17095

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... hereby given that the S.O. Conte Anadromous Fish Research Center, U.S. Geological Survey; Box 796, 1... Atlantic sturgeon (Acipenser oxyrinchus oxyrinchus) for purposes of scientific research. DATES: Written... authorization for a scientific research permit for takes of shortnose sturgeon in the wild and captivity. The...

  8. Automated Applications in an Advanced Air Traffic Management System : Volume 2B. Functional Analysis of Air Traffic Management (Cont'd.)

    DOT National Transportation Integrated Search

    1974-08-01

    Volume 2 contains the analysis and description of air traffic management activities at three levels of detail - functions, subfunctions, and tasks. A total of 265 tasks are identified and described, and the flow of information inputs and outputs amon...

  9. KTU-GEOD IVS Analysis Center Annual Report 2012

    NASA Technical Reports Server (NTRS)

    Kayikci, Emine Tanir; Teke, Kamil

    2013-01-01

    This report summarizes the activities of the KTU-GEOD IVS Analysis Center (AC) in 2012 and outlines planned activities for 2013. The analysis of the EUROPE sessions is one of our specific interests, and the combination of different AC solutions for continuous VLBI campaigns, e.g. CONT11, will be investigated.

  10. Novel deboning method of chilled broiler carcasses (prior to evisceration) and its effect on meat quality

    USDA-ARS?s Scientific Manuscript database

    During traditional poultry processing, the two main sources of contamination of the broiler carcasses are (1) microorganisms on the exterior of the carcasses, that results in skin surface contamination and (2) microorganisms from the gastrointestinal contents of the carcass and subsequent cross cont...

  11. Screening for corn rootworm (Coleoptera: Chrysomelidae) resistance to transgenic Bt corn in North Dakota

    USDA-ARS?s Scientific Manuscript database

    Western (WCR), Diabrotica virgifera virgifera LeConte, and northern corn rootworms (NCR), D. barberi Smith & Lawrence, are major economic pests of corn in much of the U.S. Corn Belt. Western corn rootworm resistance to transgenic corn expressing Bt (Bacillus thuringiensis) endotoxins has been confi...

  12. Quercetin, kaempferol, myricetin, and fatty acid content among several Hibiscus sabdariffa accession calyces based on maturity in a greenhouse

    USDA-ARS?s Scientific Manuscript database

    Flavonols including quercetin, kaempferol, myricetin, and fatty acids in plants have many useful health attributes including antioxidants, cholesterol lowering, and cancer prevention. Six accessions of roselle, Hibiscus sabdariffa calyces were evaluated for quercetin, kaempferol, and myricetin conte...

  13. Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs

    USDA-ARS?s Scientific Manuscript database

    We previously showed that parenteral nutrition (PN) compared with formula feeding results in hepatic insulin resistance and steatosis in neonatal pigs. The current aim was to test whether the route of feeding (intravenous [IV] vs enteral) rather than other feeding modalities (diet, pattern) had cont...

  14. Use of robotics for nondestructive inspection of steel highway bridges and structures : final report.

    DOT National Transportation Integrated Search

    2005-01-01

    This report presents the results of a project to finalize and apply a crawling robotic system for the remote visual inspection of high-mast light poles. The first part of the project focused on finalizing the prototype crawler robot hardware and cont...

  15. MITIGATION OF HARMFUL ALGAL BLOOMS IN THE UNITED STATES USING CLAY: RESEARCH PROGRESS AND FUTURE PERSPECTIVES

    EPA Science Inventory

    Throughout the United States, red tides and harmful algal blooms (HABs) pose a serious and recurrent threat to marine ecosystems, fisheries, human health, and coastal aesthetics. Here we report results from a research program investigating the use of clay dispersal for bloom cont...

  16. Dynamic precision phenotyping reveals mechanism of crop tolerance to root herbivory

    USDA-ARS?s Scientific Manuscript database

    The western corn rootworm, Diabrotica virgifera virgifera (LeConte) is a major pest of maize, Zea mays L. Over the years, this pest has repeatedly shown its resilience and adaptability not only to traditional crop management strategies including chemical pesticides and crop rotation, but also to de...

  17. Automation Applications in an Advanced Air Traffic Management System : Volume 2C. Functional Analysis of Air Traffic Management (Cont.'d)

    DOT National Transportation Integrated Search

    1974-08-01

    Volume 2 contains the analysis and description of air traffic management activities at three levels of detail - functions, subfunctions, and tasks. A total of 265 tasks are identified and described, and the flow of information inputs and outputs amon...

  18. Exposure to lateral collision in signalized intersections with protected left turn under different traffic control strategies.

    PubMed

    Midenet, Sophie; Saunier, Nicolas; Boillot, Florence

    2011-11-01

    This paper proposes an original definition of the exposure to lateral collision in signalized intersections and discusses the results of a real world experiment. This exposure is defined as the duration of situations where the stream that is given the right-of-way goes through the conflict zone while road users are waiting in the cross-traffic approach. This measure, obtained from video sensors, makes it possible to compare different operating conditions such as different traffic signal strategies. The data from a real world experiment is used, where the adaptive real-time strategy CRONOS (ContRol Of Networks by Optimization of Switchovers) and a time-plan strategy with vehicle-actuated ranges alternately controlled an isolated intersection near Paris. Hourly samples with similar traffic volumes are compared and the exposure to lateral collision is different in various areas of the intersection and various traffic conditions for the two strategies. The total exposure under peak hour traffic conditions drops by roughly 5 min/h with the CRONOS strategy compared to the time-plan strategy, which occurs mostly on entry streams. The results are analyzed through the decomposition of cycles in phase sequences and recommendations are made for traffic control strategies. Copyright © 2011 Elsevier Ltd. All rights reserved.

  19. Susceptibility of Nebraska Western Corn Rootworm (Coleoptera: Chrysomelidae) Populations to Bt Corn Events

    USDA-ARS?s Scientific Manuscript database

    Transgenic plants have been widely adopted by growers to manage the western corn rootworm, Diabrotica virgifera virgifera LeConte, in field corn. Because of reduced efficacy in some Nebraska fields after repeated use of Cry3Bb1 expressing hybrids, single plant bioassays were conducted in 2012 and 20...

  20. TMDLS FOR NPS POLLUTION IN LONG CREEK AND OTHER URBAN STREAMS IN MAINE USING STRESSOR IDENTIFICATIO

    EPA Science Inventory

    A. EPA's stressor identification methodology will be applied to a considerable amount of data already collected by ME DEP for the Long Creek stream assessment project funded by EPA New England. (Susan Cormier, EPA-ORD Cinn., has agreed to participate and provide some cont...

  1. Toxic and behavioral effects of free fatty acids on western corn rootworm (Coleoptera: Chrysomelidae) larvae

    USDA-ARS?s Scientific Manuscript database

    Feeding behavior, feeding intensity and staying behavior of neonate western corn rootworm (Diabrotica virgifera virgifera LeConte) larvae were evaluated in response to synthetic feeding stimulant blends. All of the treatments contained a 3-sugar blend (glucose:fructose:sucrose, 30:4:4 mg per ml) an...

  2. Verbenone: Dose-Dependent Interruption of Pheromone-Based Attraction of Three Sympatric Species of Pine Bark Beetles (Coleoptera: Scolytidae)

    Treesearch

    Daniel R. Miller; John H. Borden; B. Staffan Lindgren

    1995-01-01

    Verbenone significantly reduced catches of Ips latidens (LeConte), I. pini (Say), and Dendroctonus ponderosae Hopkins in multiple-funnel traps, baited with aggregation pheromones, in stands of lodgepole pine in southern British Columbia. Interruption of attraction was dose dependent for all three species. There...

  3. Defense Technical Information Center Thesaurus

    DTIC Science & Technology

    2000-10-01

    acquisition radar 4 + Indicates existence of further generic levels of the term DTIC Thesaurus Actuators Acridines Actinide series (cont.) Activated sintering...BT Heterocyclic compounds+ Uranium+ BT Sintering Acrilan Actinide series compounds Activated sludge process use Acrylonitrile polymers RT Actinide...Waste treatment+ Protactinium compounds Acronyms Thorium compounds+ Activation use Abbreviations Transuranium compounds+ UF Energizing Uranium compounds

  4. Evaluation of multiple funnel traps and stand characteristics for estimating western pine beetle-caused tree mortality

    Treesearch

    C.J. Hayes; C.J. Fettig; L.D. Merrill

    2009-01-01

    The western pine beetle, Dendroctonus brevicomis LeConte (Coleoptera: Curculionidae: Scolytinae), is a major cause of ponderosa pine, Pinus ponderosa Dougl. ex Laws., mortality in much of western North America. This study was designed to quantify relationships between western pine beetle trap catches [including those of its...

  5. Use of vegetated drainage ditches and low-grade weirs for aquaculture effluent mitigation: II. Suspended sediment

    USDA-ARS?s Scientific Manuscript database

    Total suspended solids are a priority pollutant under the Clean Water Act and a point of concern for aquaculture facilities. The use of ubiquitous vegetated ditches on the aquaculture landscape may serve as an environmentally and economically sustainable practice for reducing suspended sediment cont...

  6. Intelligent Transportation Systems/Commercial Vehicle Operations Project Plan For Commercial Vehicle Information Systems And Networks Electronic Data Interchange Standards Development And Deployment

    DOT National Transportation Integrated Search

    1996-12-02

    THE PURPOSE OF THIS DOCUMENT IS TO PROVIDE INFORMATION ON THE PLANNING FOR THE DEVELOPMENT AND DEPLOYMENT OF EDI STANDARDS FOR COMMERCIAL VEHICLE INFORMATION SYSTEMS AND NETWORKS (CVISN). THE STATUS, PRIORITIES, AND SCHEDULES FOR THIS EFFORT ARE CONT...

  7. PILOT-SCALE INCINERATION TESTING OF FLUFF AND SOIL FROM THE M.W. MANUFACTURING SUPERFUND SITE

    EPA Science Inventory

    A series of six tests was performed on wastes (fluff and contaminated soil) from the M.W. Manufacturing Superfund Site to determine the efficacy of incineration as the proposed remediation technology. he fluff, which is the insulation from scrap wire, and the soil wastes are cont...

  8. Protandry of western corn rootworm (Coleoptera: Chrysomelidae) beetle emergence partially due to earlier egg hatch of males

    USDA-ARS?s Scientific Manuscript database

    The western corn rootworm, Diabrotica virgifera virgifera LeConte, exhibits protandry. The contribution of pre-hatch development to protandry in western corn rootworm was previously investigated with a small set of data from one population. To verify the contribution of pre-hatch development to prot...

  9. U.S. EPA, Pesticide Product Label, ROCKLAND KLEEN-KOW CONCENTRATE DAIRY & LIVESTOCK SPRAY CONT. CIODRIN &, 12/17/1968

    EPA Pesticide Factsheets

    2011-04-14

    ... "~-' ;c-+:cns 1 .... ._""- .. u,-_ u~c ~ack~~Lbers or ~ace ru~~e~~ ~ce ~l;es, ~'lX 1 :uart "~r 4 ~a!lQ~s . ) .". trJt1on. :_1~:; ~a': ~e ~~e:;el !~e~ cr ...

  10. PLACE-BASED GREEN BUILDING: INTEGRATING LOCAL ENVIRONMENTAL AND PLANNING ANALYSIS INTO GREEN BUILDING GUIDELINES

    EPA Science Inventory

    This project will develop a model for place-based green building guidelines based on an analysis of local environmental, social, and land use conditions. The ultimate goal of this project is to develop a methodology and model for placing green buildings within their local cont...

  11. Prediction of contamination potential of groundwater arsenic in Cambodia, Laos, and Thailand using artificial neural network

    USDA-ARS?s Scientific Manuscript database

    The arsenic (As) contamination of groundwater has increasingly been recognized as a major global issue of concern. As groundwater resources are one of most important freshwater sources for water supplies in Southeast Asian countries, it is important to investigate the spatial distribution of As cont...

  12. Attraction of Pissodes affinis and P. fasciatus (Coleoptera: Curculionidae) to pityol and a-pinene in a Coastal Stand of Western White Pine and Douglas-fir

    Treesearch

    Daniel R. Miller; Don Heppner

    1999-01-01

    Lindgren multiple-funnel traps, baited with (-)-a-pinene and (±)-pityol, captured significant numbers of the weevils, Pissodes affinis Randall and P. fasciatus LeConte, in a coastal stand of Douglas-fir and western white pine.

  13. Resistance in Cultivated Sunflower Germplasm to the Red Sunflower Seed Weevil (Coleoptera: Curculionidae) in the Northern Great Plains

    USDA-ARS?s Scientific Manuscript database

    A 6-year field study evaluated 52 sunflower, Helianthus annuus L., accessions, 20 breeding lines, and 9 interspecific crosses for resistance to infestation by naturally occurring populations of the red sunflower seed weevil, Smicronyx fulvus LeConte (Coleoptera: Curculionidae). Germplasm with potent...

  14. Efficacy of verbenone for protecting ponderosa pine stands from western pine beetle (Coleoptera: Curculionidae, Scolytinae) attack in California

    Treesearch

    C.J. Fettig; S.R. McKelvey; R.R. Borys; C.P Dabney; S.M. Hamud; L.J. Nelson; S.J. Seybold

    2009-01-01

    The western pine beetle, Dendroctonus brevicomis LeConte (Coleoptera: Curculionidae: Scolytinae), is a major cause of ponderosa pine, Pinus ponderosa Dougl. ex Laws., mortality in much of western North America. Currently, techniques for managing D. brevicomis infestations are limited. Verbenone (4,6,6-...

  15. Meteorological Instrumentation Support for an Adverse Weather Test Facility

    DTIC Science & Technology

    1991-05-01

    pressure sensor 12 8 Sling psychrometer 12 9 Relative humidity graph 13 10 Relative humidity graph 13 FIGURES (cont) Page 11 Cooled mirror dewpoint...80 -80 -50 -50 -32 .32 WET BULB DRY BULB Figure 8. Sling psychrometer 12 40 -. w 0 ARYBULAI TEMPERATURE Figure 1. Relative humidity graph 3013 L

  16. Influence of weed species and time of glyphosate application on Rhizoctonia root rot of barley

    USDA-ARS?s Scientific Manuscript database

    Rhizoctonia solani AG-8 causes root disease in wheat, barley, canola and other small grains in the dryland inland Pacific Northwest. The pathogen survives between crops on roots of volunteers and grassy weeds. Destroying this green bridge with herbicides such as glyphosate is a common tactic to cont...

  17. First report of root rot caused by Phytopythium helicoides on pistachio rootstock in California

    USDA-ARS?s Scientific Manuscript database

    We examined pathogenicity of Phytopythium helicoides on UCB-1 rootstock to investigate its role in root disease and collapse observed on potted pistachio plants. Approximately 25 potted 2-year-old pistachio rootstock trees in a Kern County, CA, research plot maintained outdoors and irrigated to cont...

  18. Seasonal abundance, arrival and emergence patterns of predaceous hister beetles (Coleoptera: Histeridae) associated with Ips engraver beetles (Coleoptera: Scolytidae) in Louisiana

    Treesearch

    William P. Shepherd; Richard A. Goyer

    2003-01-01

    The most common predaceious hister beetles (Coleoptera: Histeridae) found associated with Ips engraver beetles (Coleoptera: Scolytidae) in southern Louisiana were Platysoma attenuata LeConte, P. cylindrica (Paykull), P. parallelum (Say), and Plegaderus transversus (Say). The seasonal abundance of...

  19. Polyploidy in the common tree toad Hyla versicolor Le Conte.

    PubMed

    Wasserman, A O

    1970-01-23

    A karyotype of the first known naturally occurring anuran polyploid in North America is described. Hyla versicolor, the common tree toad, is tetraploid (2n-->4n=48). Individual chromosmes representing, each set of four of the Hyla versicolor karyotype correspond closely with those of the diploid (2n = 24) Hyla andersonii karyotype.

  20. Electrophysiological and behavioral responses of Dendroctonus valens to non-host volatiles

    Treesearch

    Long-wa Zhang; Nancy E. Gillette; Jiang-hua Sun

    2007-01-01

    Non-host volatiles (NHVs) that are often reported as being disruptive to coniferophagous bark beetles were tested for both electrophysiological and behavioral effects on the red turpentine beetle, Dendroctonus valens LeConte (Coleoptera: Curculionidae: Scolytinae), which was accidentally introduced into China in the mid-1980's. All NHVs tested...

  1. Temperature and Concentration Profiles in Hydrogen-Nitrous Oxide Flames.

    DTIC Science & Technology

    1986-07-01

    SECumvY CLASSIFICATION CF TIS PAGOE(hn Date. 3.,OCO 20. Abstract (Cont’d): est for flame modeler UNCLASSIFIED * SECURITY CL ASSIrIC ATION Or THIS P...Commander Naval Surface Weapons Center Commander ATTN: R. Bernecker, R-13 US Army Tank Automotive G.B. Wilmot , R-16 Command Silver Spring, MD 20902

  2. Lasting effects of soil health improvements with management changes in cotton-based cropping systems in a sandy soil

    USDA-ARS?s Scientific Manuscript database

    The soil microbial component is essential for sustainable agricultural systems and soil health. This study evaluated the lasting impacts of 5 years of soil health improvements from alternative cropping systems compared to intensively tilled continuous cotton (Cont. Ctn) in a low organic matter sandy...

  3. Development of a Dynamic Energy Budget Modeling Approach to Investigate the Effects of Temperature and Resource Limitation on Mercury Bioaccumulation in Fundulus Heteroclitus

    EPA Science Inventory

    Dynamic energy budget (DEB) theory provides a generalizable and broadly applicable framework to connect sublethal toxic effects on individuals to changes in population persistence and growth. To explore this approach, we are conducting growth and bioaccumulation studies that cont...

  4. A core set of microsatellite markers for Western Corn Rootworm (Coleoptera: Chrysomelidae) population genetics studies

    EPA Science Inventory

    Interest in the ecological and population genetics of the western corn rootworm, Diabrotica virgifera virgifera LeConte, has grown rapidly in the last few years in North America and Europe. This interest is a result of a number of converging issues related to increasing difficult...

  5. Implementing Outpatient Surgery Programs in Military Hospitals Can Reduce DoD’s Health Care Costs

    DTIC Science & Technology

    1985-05-24

    up to 1/2 palmar fascia , with single digit involvement, with or without Z-plasty or other local tissue rearrangement 26122 5830/5833 Fasciectomy...procedure codea codeb Musculoskeletal System Cont. Fasciotomy -iliotibial (tenotomy), open 27305 5831 - plantar and/or toe, subcutaneous 28008 5830/5833

  6. The eastern larch beetle in Alaska.

    Treesearch

    Richard A. Werner

    1986-01-01

    The eastern larch beetle (Dendroctonus simplex LeConte) exists throughout the range of tamarack (Larix laricina (Du Roi) K. Koch) in interior Alaska where it has a 1-year life cycle. Beetles overwinter as adults in the bark of the trunk below snowline in infested trees. Tamarack trees that are slow growing because of repeated...

  7. Synthesis and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against Aedes aegypti

    USDA-ARS?s Scientific Manuscript database

    Aedes aegypti is a major mosquito vector for the transmission of serious diseases, especially dengue and yellow fever. More than one billion people in developing countries are at risk. The widespread and continual use of pesticides can lead to resistant mosquitoes. In order to maintain mosquito cont...

  8. INTRODUCTING A THERMAL DISSIPATION PROBE SYSTEM FOR MEASURING BI-DIRECTIONAL ROOT WATER FLUX

    EPA Science Inventory

    The interest in measuring the direction and magnitude of root sapflow has accelerated in the past few years because of interest in the redistribution of water in the soil by roots. Plant roots have been shown to redistribute water between areas of soil with differing water conte...

  9. Stress Analysis of Pallet Lever Shaft

    DTIC Science & Technology

    1976-03-01

    ductile, plastic failure. 34 ^Ki’ ■^ ’- l^f. REFERENCES 1. L. Farace , "Runaway Escapement Redesign M125A1 Modular Booster", Tech... Farace 1 Attn: MDC 1 Attn: MDC-A, Mr. F. Shinaly 1 Attn: MDM 1 Attn: MDS 1 Attn: MDS-S 1 Attn: FI 1 Attn: MT Frankford Arsenal (Cont) 1

  10. MEASUREMENTS OF CAPILLARY PRESSURE-SATURATION RELATIONSHIPS AND DNAPL DISTRIBUTION IN SILICA SANDS USING LIGHT TRANSMISSION VISUALIZATION

    EPA Science Inventory

    This study is a part of an ongoing research project that aims at assessing the environmental benefits of partial DNAPL removal. The laboratory part of the research project is to examine the functional relationship between DNAPL (modeled by PCE) architecture, mass removal and cont...

  11. ABSORPTION OF CO2 IN HIGH ACRYLONITRILE CONTENT COPOLYMERS: DEPENDENCE ON ACRYLONITRILE CONTENT. (R829555)

    EPA Science Inventory

    In continuation of our goal to determine the ability of CO2 to plasticize acrylonitrile (AN) copolymers and facilitate melt processing at temperatures below the onset of thermal degradation, a systematic study has been performed to determine the influence of AN cont...

  12. Genomic patterns of nucleotide diversity in divergent populations of U.S. weedy rice

    USDA-ARS?s Scientific Manuscript database

    Weedy rice is a significant problem in cultivated rice fields throughout the world, and is an emerging threat in regions where it was previously absent. Prior research has classified weedy rice as the same species as Asian cultivated rice (Oryza sativa L.). This close genetic relationship makes cont...

  13. A Review of Australian Investigations on Aeronautical Fatigue during the Period April 1981 to March 1983.

    DTIC Science & Technology

    1983-03-01

    13. Jeffery, G.B. Plane stress and plane strain in bipolar co-ordinates. Royal Society of London, Phil . Trans. Series A, Vol. 221, 1921, pp 265-293...Commerce Central Library .../cont. DISTRIBUTfION (CONTD.) Statutory &State Authorities and Industry Ccuimonwealth Aircraft Corporation, Mr R.C. Beckett

  14. Response of western pine beetle, Dendroctonus brevicomis LeConte (Coleoptera: Curculionidae), to different release rates of nonhost angiosperm volatiles and verbenone

    Treesearch

    C.J. Fettig; S.R. McKelvey; C.P. Dabney; R.R. Borys; D.P.W. Huber

    2009-01-01

    A blend of eight nonhost angiosperm volatiles (benzyl alcohol, benzaldehyde, guaiacol, nonanal, salicylaldehyde, (E)-2-hexenal, (E)-2-hexen-1-ol and (Z)-2-hexen-1-ol) without [NAV] and with [NAVV] (–)-verbenone (4,6,6-trimethylbicyclo[3...

  15. Fire Protection of Large Air Force Hangars

    DTIC Science & Technology

    1975-10-01

    Aqueous Film - Forming Foam ( AFFF ) in an environment...determining further the effectiveness of 3-percent aqueous film forming foam ( AFFF ); b) determining the effectiveness of AFFF systems at high ceiling...Id SUPPLEMENTARY NOTES 19. KEY WORDS fCont/nu» on reverse side If necessary and Identify by block number) Aqueous Film Forming Foam

  16. 4-allylanisole as an inhibitor of bark beetle (Coleoptera: Scolytidae) aggregation

    Treesearch

    Jane L. Hayes; Brian L. Strom

    1994-01-01

    To assess the extent of inhibitory activity of the host compound 4-allylanisole, we conducted field studies with three scolytid species.These species are geographically widespread and economically important.Trials were completed with Dendroctonus brevicomis LeConte (California), D. ponderosae Hopkins (Oregon), and Ips pini (Say) (Wisconsin) by using multiple-funnel...

  17. EVALUATION OF THREE CLEANING METHODS FOR REMOVING ASBESTOS FROM CARPET. DETERMINATION OF AIRBORNE ASBESTOS CONCENTRATIONS ASSOCIATED WITH EACH METHOD

    EPA Science Inventory

    This study was conducted to compare the effectiveness of three cleaning methods to remove asbestos from contaminated carpet and to determine the airborne asbestos concentrations associated with the use of each method. The carpet on which the methods were tested was naturally cont...

  18. Field-based assessment of resistance to Bt Corn by Western Corn Rootworm (Coleoptera: Chrysomelidae)

    USDA-ARS?s Scientific Manuscript database

    Western corn rootworm, Diabrotica virgifera virgifera LeConte, is a serious pest of corn and is managed with Bt corn that produce insecticidal toxins derived from the bacterium Bacillus thuringiensis (Bt). Beginning in 2009, severe injury to Bt corn producing Cry3Bb1 was observed in some cornfields ...

  19. Dendroctonus brevicomis responses in behavioral assays: Implication to development of a semiochemical-based tool for tree protection

    Treesearch

    Christopher J. Fettig; Stephen R. McKelvey; Christopher P. Dabney; Dezene P.W. Huber

    2012-01-01

    Currently, techniques for managing western pine beetle, Dendroctonus brevicomis LeConte (Coleoptera: Curculionidae, Scolytinae), infestations are limited to tree removals (thinning) that reduce stand density and presumably host susceptibility, and/or the use of insecticides to protect individual trees. There continues to be significant interest in...

  20. Enhancement of healing in osteochondral defects by collagen sponge implants.

    PubMed

    Speer, D P; Chvapil, M; Volz, R G; Holmes, M D

    1979-10-01

    Implants of porous, highly cross-linked collagen sponge (CS) were tested for their capacity to enhance the healing of osteochondral defects in rabbits. Comparison was made to the healing of similar defects with polyvinyl alcohol sponge (PVAS) implants and with no implants (CONT). Evaluation was carried out up to 44 weeks following implantation and included observation of host cellular response, biodegradability of implant, gross appearance of restored joint surface, collagenous architecture of repair tissue, and properties of the junctions of implants and host articular cartilage, subchondral bone, and medullary bone. Collagen sponge proved most effective in promoting healing of osteochondral defects with fibrous and fibrocartilaginous tissue over restored subchondral bone. Collagen sponge showed many desirable properties as a potential material for biologic resurfacing of damaged joints. These properties included porosity, biodegradability, biocompatability, ability to mechanically protect cells and matrix while directing cell ingrowth, and an available chemical technology for modifying its biomechanical and biological properties. Comparative analysis of results of healing of CS, PVAS, and CONT osteochondral defects suggest rational design criteria for implant materials to improve their effectiveness in restoration of articular surfaces.

  1. Silvio O. Conte National Fish and Wildlife Refuge: Draft comprehensive conservation plan and environmental impact statement

    USGS Publications Warehouse

    ,; Donovan, Elizabeth; Gascoigne, William; Cullinane Thomas, Catherine

    2015-01-01

    The Connecticut River is treasured by all for its majesty and significance in supporting life along its winding 410-mile passage through urban and rural communities in New Hampshire, Vermont, Massachusetts, and Connecticut. Working with our partners, we are inspired to protect and enhance the natural and cultural richness throughout the watershed, especially on lands and waters entrusted to our agency as the Silvio O. Conte National Fish and Wildlife Refuge. Together with our partners, we design, support, and implement strategic conservation actions across the watershed, and communicate conservation needs and successes through extensive outreach and education programs. On refuge lands, we offer visitor programs and activities that promote an appreciation of the Connecticut River watershed as an intact, interconnected, and healthy ecosystem. Visitors respond to this greater awareness by becoming active stewards of the watershed’s natural and cultural resources. Our actions exemplify the Service’s vital role in conserving the Connecticut River watershed and the refuge’s important contribution to the mission of the National Wildlife Refuge System.

  2. Trends in Social Science: The Impact of Computational and Simulative Models

    NASA Astrophysics Data System (ADS)

    Conte, Rosaria; Paolucci, Mario; Cecconi, Federico

    This paper discusses current progress in the computational social sciences. Specifically, it examines the following questions: Are the computational social sciences exhibiting positive or negative developments? What are the roles of agent-based models and simulation (ABM), network analysis, and other "computational" methods within this dynamic? (Conte, The necessity of intelligent agents in social simulation, Advances in Complex Systems, 3(01n04), 19-38, 2000; Conte 2010; Macy, Annual Review of Sociology, 143-166, 2002). Are there objective indicators of scientific growth that can be applied to different scientific areas, allowing for comparison among them? In this paper, some answers to these questions are presented and discussed. In particular, comparisons among different disciplines in the social and computational sciences are shown, taking into account their respective growth trends in the number of publication citations over the last few decades (culled from Google Scholar). After a short discussion of the methodology adopted, results of keyword-based queries are presented, unveiling some unexpected local impacts of simulation on the takeoff of traditionally poorly productive disciplines.

  3. The Hydraenidae of Cuba (Insecta: Coleoptera) II: Morphology of preimaginal stages of six species and notes on their biology.

    PubMed

    Deler-Hernández, Albert; Delgado, Juan A

    2017-03-06

    Preimaginal stages of the six species of Hydraenidae presently known from Cuba were obtained by rearing adults in the laboratory. Eggs of Hydraena perkinsi Spangler, 1980, H. decui Spangler, 1980 and H. franklyni Deler-Hernández & Delgado, 2012 are described and illustrated for the first time. The first instar larva of Gymnochthebius fossatus (LeConte, 1855) is redescribed, adding some new remarkable morphological characters including what could be the first abdominal egg-burster reported for this family. All larval instars of H. perkinsi, H. guadelupensis Orchymont, 1923 and Ochthebius attritus LeConte, 1878 are described and illustrated for the first time, with a special emphasis on their chaetotaxy. The second instar larva of G. fossatus along with first and third instar larvae of H. decui and H. franklyni are also studied for the first time. The pupal morphology and vestiture of a species belonging to the genus Hydraena are described for the first time, based on the pupa of H. perkinsi. Biological notes for several preimaginal stages of the studied species are also given.

  4. Exposure to hot and cold environmental conditions does not affect the decision making ability of soccer referees following an intermittent sprint protocol.

    PubMed

    Taylor, Lee; Fitch, Natalie; Castle, Paul; Watkins, Samuel; Aldous, Jeffrey; Sculthorpe, Nicholas; Midgely, Adrian; Brewer, John; Mauger, Alexis

    2014-01-01

    Soccer referees enforce the laws of the game and the decisions they make can directly affect match results. Fixtures within European competitions take place in climatic conditions that are often challenging (e.g., Moscow ~ -5°C, Madrid ~30°C). Effects of these temperatures on player performance are well-documented; however, little is known how this environmental stress may impair cognitive performance of soccer referees and if so, whether exercise exasperates this. The present study aims to investigate the effect of cold [COLD; -5°C, 40% relative humidity (RH)], hot (HOT; 30°C, 40% RH) and temperate (CONT; 18°C, 40% RH) conditions on decision making during soccer specific exercise. On separate occasions within each condition, 13 physically active males; either semi-professional referees or semi-professional soccer players completed three 90 min intermittent treadmill protocols that simulated match play, interspersed with 4 computer delivered cognitive tests to measure vigilance and dual task capacity. Core and skin temperature, heart rate, rating of perceived exertion (RPE) and thermal sensation (TS) were recorded throughout the protocol. There was no significant difference between conditions for decision making in either the dual task (interaction effects: FALSE p = 0.46; MISSED p = 0.72; TRACKING p = 0.22) or vigilance assessments (interaction effects: FALSE p = 0.31; HIT p = 0.15; MISSED p = 0.17) despite significant differences in measured physiological variables (skin temperature: HOT vs. CONT 95% CI = 2.6 to 3.9, p < 0.001; HOT vs. COLD 95% CI = 6.6 to 9.0, p < 0.001; CONT vs. COLD 95% CI = 3.4 to 5.7, p < 0.01). It is hypothesized that the lack of difference observed in decision making ability between conditions was due to the exercise protocol used, as it may not have elicited an appropriate and valid soccer specific internal load to alter cognitive functioning.

  5. Validation of the adherence questionnaire for Brazilian chronic kidney disease patients under hemodialysis.

    PubMed

    Lins, Silvia Maria de Sá Basilio; Leite, Josete Luzia; Godoy, Simone de; Fuly, Patrícia Dos Santos Claro; Araújo, Silvia Teresa Carvalho de; Silva, Ítalo Rodolfo

    2017-01-01

    To validate the evaluation questionnaire on adherence of chronic kidney disease (CKD) patients under hemodialysis. We verified the following psychometric properties of the instrument: reliability (stability and internal consistency) and validity (face, content, and construct). The intraclass correlation coefficient reached a value of 0.98 for the adherence questions and 0.91 for the perception questions. Regarding the kappa of the 14 questions examined, 12 had a value > 0.8, whereas the Cronbach's alpha had a value of 0.57. Experts ensured the face and content validity of the instrument, giving it an overall content validity index of 0.96. Construct validity, analyzed by Mann-Whitney test, was achieved as all domains showed a significant association with p<0.01. We verified, by the presented results, that the instrument has been validated for use in Brazil. Validar o questionário de avaliação sobre a adesão do portador de doença renal crônica em hemodiálise. Foram verificadas as seguintes propriedades psicométricas do instrumento: confiabilidade (estabilidade e consistência interna) e validade (de face, de conteúdo e de construto). O coeficiente de correlação intraclasse atingiu valor de 0,98 para as questões de adesão e 0,91 para as questões de percepção. Quanto ao kappa das 14 questões analisadas, 12 obtiveram um valor > 0,8. Já o alfa de Cronbach obteve valor de 0,57. Os especialistas asseguraram a validade de face e de conteúdo do instrumento, conferindo-lhe um índice de validade de conteúdo global de 0,96. A validade de construto, analisada por meio do teste de Mann-Whitney, foi alcançada na medida em que todos os domínios apresentaram uma associação significativa com p < 0,01. Verifica-se, pelos resultados apresentados, que o instrumento foi validado para uso no Brasil.

  6. Temperate Performance Benefits after Heat, but Not Combined Heat and Hypoxic Training.

    PubMed

    McCleave, Erin L; Slattery, Katie M; Duffield, Rob; Saunders, Philo U; Sharma, Avish P; Crowcroft, Stephen J; Coutts, Aaron J

    2017-03-01

    Independent heat and hypoxic exposure can enhance temperate endurance performance in trained athletes, although their combined effects remain unknown. This study examined whether the addition of heat interval training during "live high, train low" (LHTL) hypoxic exposure would result in enhanced performance and physiological adaptations as compared with heat or temperate training. Twenty-six well-trained runners completed 3 wk of interval training assigned to one of three conditions: 1) LHTL hypoxic exposure plus heat training (H + H; 3000 m for 13 h·d, train at 33°C, 60% relative humidity [RH]), 2) heat training with no hypoxic exposure (HOT, live at <600 m and train at 33°C, 60% RH), or 3) temperate training with no hypoxic exposure (CONT; live at <600 m and train at 14°C, 55% RH). Performance 3-km time-trials (3-km TT), running economy, hemoglobin mass, and plasma volume were assessed using magnitude-based inferences statistical approach before (Baseline), after (Post), and 3 wk (3wkP) after exposure. Compared with Baseline, 3-km TT performance was likely increased in HOT at 3wkP (-3.3% ± 1.3%; mean ± 90% confidence interval), with no performance improvement in either H + H or CONT. Hemoglobin mass increased by 3.8% ± 1.8% at Post in H + H only. Plasma volume in HOT was possibly elevated above H + H and CONT at Post but not at 3wkP. Correlations between changes in 3-km TT performance and physiological adaptations were unclear. Incorporating heat-based training into a 3-wk training block can improve temperate performance at 3 wk after exposure, with athlete psychology, physiology, and environmental dose all important considerations. Despite hematological adaptations, the addition of LHTL to heat interval training has no greater 3-km TT performance benefit than temperate training alone.

  7. An annotated list of aquatic insects of Fort Sill, Oklahoma, excluding diptera with notes on several new state records

    USGS Publications Warehouse

    Zuellig, R.E.; Kondratieff, B.C.; Schmidt, J.P.; Durfee, R.S.; Ruiter, D.E.; Prather, I.E.

    2006-01-01

    Qualitative collections of aquatic insects were made at Fort Sill, Lawton, Oklahoma, between 2002 and 2004. Ephemeroptera, Plecoptera, Trichoptera, Odonata, Coleoptera, aquatic Heteroptera, Neuroptera, and Megaloptera were targeted. Additional records are included from a survey that took place in 1999. More than 11,000 specimens from more than 290 collections were examined. Based on the current understanding of aquatic insect systematics, 276 taxa distributed over 8 orders, 46 families, and 141 genera were identified. Twenty-three of the 276 taxa, Plauditus texanus Wiersema, Tricorythodes allectus (Needham), Palmacorixa nana walleyi Hungerford, Climacia chapini Partin and Gurney, Oxyethira forcipata Mosely, Oxyethira janella Denning, Triaenodes helo Milne, Ylodes frontalis (Banks), Acilius fraternus Harris, Coptotomus loticus Hilsenhoff, Coptotomus venustus (Say), Desmopachria dispersa Crotch, Graphoderus liberus (Say), Hydrovatus pustulatus (Melsheimer), Hygrotus acaroides (LeConte), Liodessus flavicollis (LeConte), Uvarus texanus (Sharp), Gyrinus woodruffi Fall, Haliplus fasciatus Aube, Haliplus lewisii Crotch, Haliplus tortilipenis Brigham & Sanderson, Chaetarthria bicolor Sharp, Epimetopus costatus complex, and Hydrochus simplex LeConte are reported from Oklahoma for the first time. The three most diverse orders included Coleoptera (86 species), Odonata (67 species) and Trichoptera (59 species), and the remaining taxa were distributed among Heteroptera, (30 species), Ephemeroptera (21 species), Plecoptera (6 species), Megaloptera (4 species), and Neuroptera (3 species). Based on previous published records, many of the species collected during this study were expected to be found at Fort Sill; however, 276 taxa of aquatic insects identified from such a small geographic area is noteworthy, especially when considering local climatic conditions and the relatively small size of Fort Sill (38,300 ha). Despite agricultural practices in Oklahoma, the dust bowl days, and the development of water-based recreation at Fort Sill, a high percentage of the total known aquatic insect fauna of Oklahoma can be found in a small geographic area. ?? 2006 Kansas Entomological Society.

  8. Cold water immersion recovery after simulated collision sport exercise.

    PubMed

    Pointon, Monique; Duffield, Rob

    2012-02-01

    This investigation examined the effects of cold water immersion (CWI) recovery after simulated collision sport exercise. Ten male rugby athletes performed three sessions consisting of a 2 × 30-min intermittent-sprint exercise (ISE) protocol with either tackling (T) or no tackling (CONT), followed by a 20-min CWI intervention (TCWI) or passive recovery (TPASS and CONT) in a randomized order. The ISE consisted of a 15-m sprint every minute separated by self-paced bouts of hard running, jogging, and walking for the remainder of the minute. Every sixth rotation, participants performed 5 × 10-m runs, receiving a shoulder-led tackle to the lower body on each effort. Sprint time and distance covered during ISE were recorded, with voluntary (maximal voluntary contraction; MVC) and evoked neuromuscular function (voluntary activation; VA), electromyogram (root mean square (RMS)), ratings of perceived muscle soreness (MS), capillary and venous blood markers for metabolites and muscle damage, respectively measured before and after exercise, immediately after recovery, and 2 and 24 h after recovery. Total distance covered during exercise was significantly greater in CONT (P = 0.01), without differences between TPASS and TCWI (P > 0.05). TCWI resulted in increased MVC, VA, and RMS immediately after recovery (P < 0.05). M-wave amplitude and peak twitch were significantly increased after recovery and 2 h after recovery, respectively, in TCWI (P < 0.05). Although TCWI had no effect on the elevation in blood markers for muscle damage (P > 0.05), lactate was significantly reduced after recovery compared with TPASS (P = 0.04). CWI also resulted in reduced MS 2 h after recovery compared with TPASS (P < 0.05). The introduction of body contact reduces exercise performance, whereas the use of CWI results in a faster recovery of MVC, VA, and RMS and improves muscle contractile properties and perceptions of soreness after collision-based exercise.

  9. Novel All-Extremity High-Intensity Interval Training Improves Aerobic Fitness, Cardiac Function and Insulin Resistance in Healthy Older Adults

    PubMed Central

    Hwang, Chueh-Lung; Yoo, Jeung-Ki; Kim, Han-Kyul; Hwang, Moon-Hyon; Handberg, Eileen M.; Petersen, John W.; Christou, Demetra D.

    2016-01-01

    Aging is associated with decreased aerobic fitness and cardiac remodeling leading to increased risk for cardiovascular disease. High-intensity interval training (HIIT) on the treadmill has been reported to be more effective in ameliorating these risk factors compared with moderate-intensity continuous training (MICT) in patients with cardiometabolic disease. In older adults, however, weight-bearing activities are frequently limited due to musculoskeletal and balance problems. The purpose of this study was to examine the feasibility and safety of non-weight-bearing all-extremity HIIT in older adults. In addition, we tested the hypothesis that all-extremity HIIT will be more effective in improving aerobic fitness, cardiac function, and metabolic risk factors compared with all-extremity MICT. Fifty-one healthy sedentary older adults (age: 65±1 years) were randomized to HIIT (n=17), MICT (n=18) or non-exercise control (CONT; n=16). HIIT (4×4 minutes 90% of peak heart rate; HRpeak) and isocaloric MICT (70% of HRpeak) were performed on a non-weight-bearing all-extremity ergometer, 4x/week for 8 weeks under supervision. All-extremity HIIT was feasible in older adults and resulted in no adverse events. Aerobic fitness (peak oxygen consumption; VO2peak) and ejection fraction (echocardiography) improved by 11% (P<0.0001) and 4% (P=0.001) respectively in HIIT, while no changes were observed in MICT and CONT (P≥0.1). Greater improvements in ejection fraction were associated with greater improvements in VO2peak (r=0.57; P<0.0001). Insulin resistance (homeostatic model assessment) decreased only in HIIT by 26% (P=0.016). Diastolic function, body composition, glucose and lipids were unaffected (P≥0.1). In conclusion, all-extremity HIIT is feasible and safe in older adults. HIIT, but not MICT, improved aerobic fitness, ejection fraction, and insulin resistance. PMID:27346646

  10. Novel all-extremity high-intensity interval training improves aerobic fitness, cardiac function and insulin resistance in healthy older adults.

    PubMed

    Hwang, Chueh-Lung; Yoo, Jeung-Ki; Kim, Han-Kyul; Hwang, Moon-Hyon; Handberg, Eileen M; Petersen, John W; Christou, Demetra D

    2016-09-01

    Aging is associated with decreased aerobic fitness and cardiac remodeling leading to increased risk for cardiovascular disease. High-intensity interval training (HIIT) on the treadmill has been reported to be more effective in ameliorating these risk factors compared with moderate-intensity continuous training (MICT) in patients with cardiometabolic disease. In older adults, however, weight-bearing activities are frequently limited due to musculoskeletal and balance problems. The purpose of this study was to examine the feasibility and safety of non-weight-bearing all-extremity HIIT in older adults. In addition, we tested the hypothesis that all-extremity HIIT will be more effective in improving aerobic fitness, cardiac function, and metabolic risk factors compared with all-extremity MICT. Fifty-one healthy sedentary older adults (age: 65±1years) were randomized to HIIT (n=17), MICT (n=18) or non-exercise control (CONT; n=16). HIIT (4×4min 90% of peak heart rate; HRpeak) and isocaloric MICT (70% of HRpeak) were performed on a non-weight-bearing all-extremity ergometer, 4×/week for 8weeks under supervision. All-extremity HIIT was feasible in older adults and resulted in no adverse events. Aerobic fitness (peak oxygen consumption; VO2peak) and ejection fraction (echocardiography) improved by 11% (P<0.0001) and 4% (P=0.001), respectively in HIIT, while no changes were observed in MICT and CONT (P≥0.1). Greater improvements in ejection fraction were associated with greater improvements in VO2peak (r=0.57; P<0.0001). Insulin resistance (homeostatic model assessment) decreased only in HIIT by 26% (P=0.016). Diastolic function, body composition, glucose and lipids were unaffected (P≥0.1). In conclusion, all-extremity HIIT is feasible and safe in older adults. HIIT, but not MICT, improved aerobic fitness, ejection fraction, and insulin resistance. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Frozen Cropland Soil in Northeast China as Source of N2O and CO2 Emissions

    PubMed Central

    Qiao, Yunfa; Han, Xiaozeng; Brancher Franco, Roberta

    2014-01-01

    Agricultural soils are important sources of atmospheric N2O and CO2. However, in boreal agro-ecosystems the contribution of the winter season to annual emissions of these gases has rarely been determined. In this study, soil N2O and CO2 fluxes were measured for 6 years in a corn-soybean-wheat rotation in northeast China to quantify the contribution of wintertime N2O and CO2 fluxes to annual emissions. The treatments were chemical fertilizer (NPK), chemical fertilizer plus composted pig manure (NPKOM), and control (Cont.). Mean soil N2O fluxes among all three treatments in the winter (November–March), when soil temperatures are below −7°C for extended periods, were 0.89–3.01 µg N m−2 h−1, and in between the growing season and winter (October and April), when freeze-thaw events occur, 1.73–5.48 µg N m−2 h−1. The cumulative N2O emissions were on average 0.27–1.39, 0.03–0.08 and 0.03–0.11 kg N2O–N ha−1 during the growing season, October and April, and winter, respectively. The average contributions of winter N2O efflux to annual emissions were 6.3–12.1%. In all three seasons, the highest N2O emissions occurred in NPKOM, while NPK and Cont. emissions were similar. Cumulative CO2 emissions were 2.73–4.94, 0.13–0.20 and 0.07–0.11 Mg CO2-C ha−1 during growing season, October and April, and winter, respectively. The contribution of winter CO2 to total annual emissions was 2.0–2.4%. Our results indicate that in boreal agricultural systems in northeast China, CO2 and N2O emissions continue throughout the winter. PMID:25536036

  12. The effects of short work vs. longer work periods within intermittent exercise on V̇o2p kinetics, muscle deoxygenation, and energy system contribution.

    PubMed

    McCrudden, Michael C; Keir, Daniel A; Belfry, Glen R

    2017-06-01

    We examined the effects of inserting 3-s recovery periods during high-intensity cycling exercise at 25-s and 10-s intervals on pulmonary oxygen uptake (V̇o 2p ), muscle deoxygenation [deoxyhemoglobin (HHb)], their associated kinetics (τ), and energy system contributions. Eleven men (24 ± 3 yr) completed two trials of three cycling protocols: an 8-min continuous protocol (CONT) and two 8-min intermittent exercise protocols with work-to-rest periods of 25 s to 3 s (25INT) and 10 s to 3 s (10INT). Each protocol began with a step-transition from a 20-W baseline to a power output (PO) of 60% between lactate threshold and maximal V̇o 2p (Δ60). This PO was maintained for 8 min in CONT, whereas 3-s periods of 20-W cycling were inserted every 10 s and 25 s after the transition to Δ60 in 10INT and 25INT, respectively. Breath-by-breath gas exchange measured by mass spectrometry and turbine and vastus lateralis [HHb] measured by near-infrared spectroscopy were recorded throughout. Arterialized-capillary lactate concentration ([Lac - ]) was obtained before and 2 min postexercise. The τV̇o 2p was lowest ( P < 0.05) for 10INT (24 ± 4 s) and 25INT (23 ± 5 s) compared with CONT (28 ± 4 s), whereas HHb kinetics did not differ ( P > 0.05) between conditions. Postexercise [Lac - ] was lowest ( P < 0.05) for 10INT (7.0 ± 1.7 mM), was higher for 25INT (10.3 ± 1.9 mM), and was greatest in CONT (14.3 ± 3.1 mM). Inserting 3-s recovery periods during heavy-intensity exercise speeded V̇o 2p kinetics and reduced overall V̇o 2p , suggesting an increased reliance on PCr-derived phosphorylation during the work period of INT compared with an identical PO performed continuously. NEW & NOTEWORTHY We report novel observations on the effects of differing heavy-intensity work durations between 3-s recovery periods on pulmonary oxygen uptake (V̇o 2p ) kinetics, muscle deoxygenation, and energy system contributions. Relative to continuous exercise, V̇o 2p kinetics are faster in intermittent exercise, and increased frequency of 3-s recovery periods improves microvascular O 2 delivery and reduces V̇o 2p and arterialized-capillary lactate concentration. The metabolic burden of identical intensity work is altered when performed intermittently vs. continuously. Copyright © 2017 the American Physiological Society.

  13. Emergence, seasonality, and hybridization of Laricobius nigrinus (Coleoptera: Derodontidae), an introduced predator of hemlock woolly adelgid (Hemiptera: Adelgidae), in the Tennessee Appalachians

    Treesearch

    Gregory J. Wiggins; Jerome F. Grant; Rusty Rhea; Albert (Bud) Mayfield; Abdul Hakeem; Paris L. Lambdin; A. B. Lamb Galloway

    2016-01-01

    From 2010 through 2013, adult emergence and seasonality of Laricobius nigrinus Fender, an introduced predatoryspecies native to western North America, as well as hybridization with the native species Laricobius rubidus(LeConte), were evaluated using emergence traps and beat-sheet sampling in areas of...

  14. Geographic variation in bacterial communities associated with the red turpentine beetle (Coleoptera: Curculionidae)

    Treesearch

    Aaron S. Adams; Sandye M. Adams; Cameron R. Currie; Nancy E. Gillette; Kenneth F. Raffa

    2010-01-01

    Bacterial communities are known to play important roles in insect life histories, yet their consistency or variation across populations is poorly understood. Bacteria associated with the bark beetle Dendroctonus valens LeConte from eight populations, ranging from Wisconsin to Oregon, were evaluated and compared. We used the culture-independent technique of denaturing...

  15. Red turpentine beetle: Innocuous native becomes invasive tree killer in China

    Treesearch

    Jianghua Sun; Min Lu; Nancy E. Gillette; Michael J. Wingfield

    2012-01-01

    The red turpentine beetle (RTB), Dendroctonus valens LeConte (Coleoptera: Curculionidae: Scolytinae), is a secondary pest of pines in its native range in North and Central America. Outbreaks and tree mortality attributed to RTB alone are rare in its native range. RTB was introduced into China in the early 1980s and spread rapidly from Shanxi...

  16. Consumption of pizza in the United States, What We Eat in America, NHANES 2007-2010

    USDA-ARS?s Scientific Manuscript database

    Pizza is recognized as a high consumption food and a contributor of nutrients of public significance in the American diet including fat, calcium, and sodium. This research presents results on pizza consumption among U.S. children (2-19 years) and adults (20 years and over) and details nutrient cont...

  17. Carbon Dioxide Addition to Microbial Fuel Cell Cathodes Maintains Sustainable Catholyte pH and Improves Anolyte pH, Alkalinity, and Conductivity

    USDA-ARS?s Scientific Manuscript database

    Bioelectrochemical system (BES) pH imbalances develop due to anodic proton-generating oxidation reactions and cathodic hydroxide-ion-generating reduction reactions. Until now, workers added unsustainable buffers to reduce the pH difference between the anode and cathode because the pH imbalance cont...

  18. Weight of evidence evaluation of a network of adverse outcome pathways linking activation of the nicotinic acetylcholine receptor in honey bees to colony death

    EPA Science Inventory

    Ongoing honey bee colony losses are of significant international concern because of the essential role these insects play in pollinating many high nutrient crops, such as fruits, vegetables, and nuts. Both chemical and non-chemical stressors have been implicated as possible cont...

  19. Fir Engraver (FIDL)

    Treesearch

    George T. Ferrell

    1986-01-01

    The fir engraver, Scolytus ventralis LeConte, belongs to the family of insects called bark beetles, which live between the bark and wood of host trees. A wide-ranging, native beetle, the fir engraver attacks most species of fir in the Western United States. Epidemics can cause severe tree mortality. From 1977 to 1978, for example, the fir engraver killed an estimated 1...

  20. Sensing the Moisture Content of Dry Cherries - A Rapid and Nondestructive Method

    USDA-ARS?s Scientific Manuscript database

    Impedance (Z), and phase angle (') of a parallel-plate capacitor with a single cherry fruit between the plates was measured using a CI meter (Chari’s Impedance meter), at 1 and 9 MHz . Capacitance C, was derived from Z and ', and using the C, ', and Z values of a set of cherries whose moisture cont...

  1. Neutrophil (PMN) surface contact with keratocytes following corneal epithelial abrasion in the mouse: a novel role for ICAM-1

    USDA-ARS?s Scientific Manuscript database

    Corneal epithelial abrasion is associated with an inflammatory response that involves PMN recruitment from the limbal vessels into the corneal stroma. Previously, in the injured mouse cornea, we showed that migrating PMNs not only make contact with collagen, but they also make extensive surface cont...

  2. Effects on eastern larch beetle of its natural attractant and synthetic pheromones in Alaska.

    Treesearch

    Richard A. Werner; Malcom M. Furniss; Thomas. Ward

    1981-01-01

    Traps baited with Seudenol + a-pinene caught 87 percent more eastern larch beetles, Dendroctonus simplex LeConte, than did tamarack logs infested with females. Male beetles responded to the synthetic attractant in greater numbers than females. Male beetles were not attracted to frontalin, a principal attractant of the closely related Douglas-fir...

  3. Isolation of transcripts from Diabrotica virgifera virgifera LeConte responsive to the Bacillus thuringiensis toxin Cry3Bb1

    EPA Science Inventory

    Crystal proteins derived from Bacillus thuringiensis (Bt) have been widely used as a method of insect pest management for several decades. In recent years, a transgenic corn expressing the Cry3Bb1 toxin has been successfully used for protection against corn rootworm larvae (Genus...

  4. EFFECTS OF CO2 AND TEMPERATURE ON FINE ROOT PRODUCTION AND MORTALITY IN DOUGLAS FIR

    EPA Science Inventory

    Little is known about the effects of global climate change on the production and mortality of fine roots. We conducted a 4-year study to determine the effects of elevated CO2 and temperature on Douglas fir fine ( 2 mm in diameter) roots. The study was conducted in sun-lit cont...

  5. A new artificial diet for western corn rootworm larvae is compatible with and detects resistance to all current Bt toxins

    USDA-ARS?s Scientific Manuscript database

    Insect resistance to transgenic crops expressing one or more genes from Bacillus thuringiensis Berliner (Bt) is a growing concern for farmers, regulatory agencies, the seed industry, and researchers alike. Western corn rootworm (Diabrotica virgifera virgifera LeConte) is a pest of corn (Zea mays L.)...

  6. Anthropometry of a Fit Test Sample used in Evaluating the Current and Improved MCU-2/P Masks

    DTIC Science & Technology

    1989-03-01

    METHOD Forty-two head and face measurements were taken on each subject after he/she had completed MSA’s series of fit tests. Of these, 15 were measured...BREADTH Using spreading calipers, the hori- zontal distance between the fronto- temporale landmarks. 25 MEASUREMENT DESCRIPTIONS (cont’d) 13. NASAL

  7. Pinyon Needle Scale (FIDL)

    Treesearch

    William F. McCambridge

    1994-01-01

    The pinyon needle scale (Matsucoccus acalyptus Herbert) is a native sap-sucking insect found in the Southwest. Feeding by scales weakens trees by killing needles older than 1 year. Sometimes small trees are killed by repeated feeding and large trees weakened to such an extent that they fall victims to attack by the bark beetle Ips confusus (LeConte). Scale infestations...

  8. The Impact of Accelerating Information Technology on War and Peace

    DTIC Science & Technology

    2008-12-01

    first I thought that you had done something clever, but I see that there was nothing in it, after all” – said to Sherlock Holmes “I begin to think that...I make a mistake in explaining.” – Sherlock Holmes The Criticism from software cont. Software complexity and performance is improving Especially in

  9. Acetophenone superior to verbenone for reducing attraction of western pine beetle Dendroctonus brevicomis to its aggregation pheromone

    Treesearch

    Nadir Erbilgin; Nancy E. Gillette; Donald R. Owen; Sylvia R. Mori; Andrew S. Nelson; Fabian C.C. Uzoh; David L. Wood

    2008-01-01

    The western pine beetle Dendroctonus brevicomis LeConte (Coleoptera: Scolytidae) is one of the most damaging insect pests of ponderosa pines Pinus ponderosa Douglas ex P. & C. Lawson in Western U.S.A. We compared the effect of verbenone, a well known bark beetle anti-aggregation pheromone, with that...

  10. Effect of high pressure on peanut allergens in the presence of polyphenol oxidase and caffeic acid

    USDA-ARS?s Scientific Manuscript database

    High pressure (HP) enhances enzymatic reactions. Because polyphenol oxidase (PPO) is an enzyme, and reduces IgE binding of peanut allergens in presence of caffeic acid (CA), we postulated that a further reduction in IgE binding can be achieved, using HP together with PPO and CA. Peanut extracts cont...

  11. Below-ground effects of enhanced tropospheric ozone and drought in a beech/spruce forest (Fagus sylvatica L. / Picea abies [L.] Karst)

    EPA Science Inventory

    The effects of experimentally elevated O3 on soil respiration rates, standing fine-root biomass, fine-root production and δ13C signature of newly produced fine roots were investigated in an adult European beech/Norway spruce forest in Germany during two subsequent years with cont...

  12. Susceptibility of Trogoderma granarium Everts and Trogoderma inclusum LeConte (Coleoptera: Dermestidae) to residual contact insecticides

    USDA-ARS?s Scientific Manuscript database

    Two pyrethroid insecticides were evaluated on concrete arenas for their efficacy against Trogoderma granarium and T. inclusum larvae. Ten larvae of either species were exposed to treated arenas for 1, 2, 3, and 7 d then transferred into 175 ml cups with diet for 30 d to evaluate delayed mortality. I...

  13. 6. DETAIL VIEW OF BRIDGE DATEPLATE WHICH READS '1930, WHITE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. DETAIL VIEW OF BRIDGE DATEPLATE WHICH READS '1930, WHITE RIVER BRIDGE, ARKANSAS HIGHWAY COMMISSION, DWIGHT BLACKWOOD, CHAIRMAN, JUSTIN MATTHEWS, J. LAN WILLIAMS, J.S. PARKS, SAM J. WILSON, COMMISSIONERS, C.S. CHRISTIAN, STATE HIGHWAY ENGINEER, IRA HEDRICK, INC., CONSULTING ENGINEERS, PARHAM CONT. CO., CONTRACTOR' - Augusta Bridge, Spanning White River at Highway 64, Augusta, Woodruff County, AR

  14. Pallidus beetle, Delphastus pallidus LeConte (Insecta: Coleoptera: Coccinellidae), a native predatory beetle of whitefly species in Florida

    USDA-ARS?s Scientific Manuscript database

    Beetles in the genus Delphastus Casey are small whitefly-specific predatory ladybird beetles belonging to the coccinellid tribe Serangiini. They feed on all immature stages of whitefly and are reared and sold commercially all over the world for this purpose. They are compatible with the application ...

  15. Selected Logistics Models and Techniques.

    DTIC Science & Technology

    1984-09-01

    TI - 59 Programmable Calculator LCC...Program 27 TI - 59 Programmable Calculator LCC Model 30 Unmanned Spacecraft Cost Model 31 iv I: TABLE OF CONTENTS (CONT’D) (Subject Index) LOGISTICS...34"" - % - "° > - " ° .° - " .’ > -% > ]*° - LOGISTICS ANALYSIS MODEL/TECHNIQUE DATA MODEL/TECHNIQUE NAME: TI - 59 Programmable Calculator LCC Model TYPE MODEL: Cost Estimating DEVELOPED BY:

  16. Effect of transgenic corn hybrids and a soil insecticide on corn rootworm (Coleoptera: Chrysomelidae) beetle emergence in North Dakota

    USDA-ARS?s Scientific Manuscript database

    Northern, Diabrotica barberi Smith & Lawrence, and western corn rootworms, D. virgifera virgifera LeConte, are economic pests of corn, Zea mays L. (Poaceae) in North Dakota. Many area corn growers rely on transgenic Bt (Bacillus thuringiensis) corn hybrids to manage corn rootworms. Our objective was...

  17. Larval mortality and development for rotation-resistant and rotation-susceptible populations of the western corn rootworm on Bt corn

    USDA-ARS?s Scientific Manuscript database

    The western corn rootworm, Diabrotica virgifera virgifera LeConte, is one of the most economically important insect pests threatening the production of corn, Zea mays (L.), in the United States. Throughout its history, this insect has displayed considerable adaptability by overcoming a variety of pe...

  18. Commercial Maritime Information: A Critical Appraisal.

    DTIC Science & Technology

    1981-01-01

    Robert W. Mason, Chief, Information and Analysis Staff vi Liaison Representative (Cont’d) Department of Transportation James L. Duda, Acting Chief...Christensen, Program Manager, Market Analysis , Office of Market Development John M. Pisani, Alternate, Program Manager, Office of Ports and...Intermodal Development Military Traffic Management Command David Goodman, Chief, Management Analysis Division, Comptroller/Directorate John C. Kuypers, LTC

  19. Responses of Dendroctonus brevicomis (Coleoptera: Curculionidae) in behavioral assays: Implications to development of a semiochemical-based tool for tree protection

    Treesearch

    Christopher J. Fettig; Stephen R. McKelvey; Christopher P. Dabney; Dezene P.W. Huber

    2012-01-01

    Currently, techniques for managing western pine beetle, Dendroctonus brevicomis LeConte (Coleoptera: Curculionidae, Scolytinae), infestations are limited to tree removals (thinning) that reduce stand density and presumably host susceptibility, and/or the use of insecticides to protect individual trees. There continues to be significant interest in...

  20. Translation, adaptation and validation the contents of the Diabetes Medical Management Plan for the Brazilian context.

    PubMed

    Torres, Heloísa de Carvalho; Chaves, Fernanda Figueredo; Silva, Daniel Dutra Romualdo da; Bosco, Adriana Aparecida; Gabriel, Beatriz Diniz; Reis, Ilka Afonso; Rodrigues, Júlia Santos Nunes; Pagano, Adriana Silvina

    2016-08-08

    to translate, adapt and validate the contents of the Diabetes Medical Management Plan for the Brazilian context. This protocol was developed by the American Diabetes Association and guides the procedure of educators for the care of children and adolescents with diabetes in schools. this methodological study was conducted in four stages: initial translation, synthesis of initial translation, back translation and content validation by an expert committee, composed of 94 specialists (29 applied linguists and 65 health professionals), for evaluation of the translated version through an online questionnaire. The concordance level of the judges was calculated based on the Content Validity Index. Data were exported into the R program for statistical analysis. the evaluation of the instrument showed good concordance between the judges of the Health and Applied Linguistics areas, with a mean content validity index of 0.9 and 0.89, respectively, and slight variability of the index between groups (difference of less than 0.01). The items in the translated version, evaluated as unsatisfactory by the judges, were reformulated based on the considerations of the professionals of each group. a Brazilian version of Diabetes Medical Management Plan was constructed, called the Plano de Manejo do Diabetes na Escola. traduzir, adaptar e validar o conteúdo do Diabetes Medical Management Plan para o contexto brasileiro, protocolo elaborado pela Associação Americana de Diabetes, que orienta a conduta dos educadores para o cuidado das crianças e adolescentes com diabetes mellitus nas escolas. trata-se de estudo metodológico, realizado em quatro etapas: tradução inicial, síntese da tradução inicial, retrotradução e validação de conteúdo por um Comitê de Juízes, composto por 94 especialistas (29 linguistas aplicados e 65 profissionais da área da Saúde), para avaliação da versão traduzida por meio de um questionário online. O nível de concordância dos juízes foi calculado com base no Índice de Validade de Conteúdo. Os dados coletados foram exportados para análise estatística no ambiente R. a avaliação do instrumento apresentou boa concordância entre os juízes das áreas da Saúde e Linguística Aplicada, com Índice de Validade de Conteúdo médio de 0,9 e 0,89, respectivamente, e pequena variabilidade do índice entre grupos (diferença inferior a 0,01). Os itens da versão traduzida, avaliados como insatisfatórios pelos juízes, foram reformulados com base nas ponderações dos profissionais de cada grupo. construiu-se uma versão brasileira do Diabetes Medical Management Plan, denominado Plano de Manejo do Diabetes na Escola. traducir, adaptar y validar el contenido del Diabetes Medical Management Plan para el contexto brasileño, protocolo elaborado por la Asociación de Diabetes Americana, que orienta la conducta de los educadores para el cuidado de niños y adolescentes con diabetes mellitus en las escuelas. se trata de estudio metodológico, realizado en cuatro etapas: traducción inicial, síntesis de la traducción inicial, retrotraducción y validación de contenido por un Comité de Jueces, compuesto por 94 especialistas (29 lingüistas aplicados y 65 profesionales del área de la Salud), para evaluación de la versión traducida por medio de un cuestionario online. El nivel de concordancia de los jueces fue calculado con base en el Índice de Validez de Contenido. Los datos recolectados fueron exportados para ser analizados estadísticamente en el ambiente R. la evaluación del instrumento presentó buena concordancia entre los jueces de las áreas de Salud y Lingüística Aplicada, con Índice de Validez de Contenido promedio de 0,9 y 0,89, respectivamente, y pequeña variabilidad del índice entre grupos (diferencia inferior a 0,01). Los ítems de la versión traducida, evaluados como insatisfactorios por los jueces, fueron reformulados con base en las sugestiones de los profesionales de cada grupo. se construyó una versión brasileña del Diabetes Medical Management Plan, denominado Plan de Administración de la Diabetes en la Escuela.

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