Series resonance inverter with triggered vacuum gaps

NASA Astrophysics Data System (ADS)

Damstra, Geert C.; Zhang, X.

1994-05-01

Series resonance inverters based on semi-conductor switching elements are well-known and have a wide range of application, mainly for lower voltages. For high voltage application many switching elements have to be put in series to obtain sufficient blocking voltage. Voltage grinding and multiple gate control elements are needed. There is much experience with the triggered vacuum gaps as high voltage/high current single shot elements, for example in reignition circuits for synthetic circuit breaker tests. These elements have a blocking voltage of 50 - 100 kV and are triggerable by a light fiber control device. A prototype inverter has been developed that generates 0.1 Hz, 30 kV AC voltages with a flat top for tests on cables and capacitors of many micro farads fed from a low voltage supply of about 600 V. Only two TVG elements are needed to switch the resonant circuit alternatively on the positive or negative supply. The resonant circuit itself consists of the capacitance of the testobject and a high quality inductor that determines the frequency and the peak current of the voltage reversing process.

Optical distributed sensors for feedback control: Characterization of photorefractive resonator

NASA Technical Reports Server (NTRS)

Indebetouw, Guy; Lindner, D. K.

1992-01-01

The aim of the project was to explore, define, and assess the possibilities of optical distributed sensing for feedback control. This type of sensor, which may have some impacts in the dynamic control of deformable structures and the monitoring of small displacements, can be divided into data acquisition, data processing, and control design. Analogue optical techniques, because they are noninvasive and afford massive parallelism may play a significant role in the acquisition and the preprocessing of the data for such a sensor. Assessing these possibilities was the aim of the first stage of this project. The scope of the proposed research was limited to: (1) the characterization of photorefractive resonators and the assessment of their possible use as a distributed optical processing element; and (2) the design of a control system utilizing signals from distributed sensors. The results include a numerical and experimental study of the resonator below threshold, an experimental study of the effect of the resonator's transverse confinement on its dynamics above threshold, a numerical study of the resonator above threshold using a modal expansion approach, and the experimental test of this model. A detailed account of each investigation, including methodology and analysis of the results are also included along with reprints of published and submitted papers.

Cushing's Syndrome

MedlinePlus

... resonance imaging (MRI) scan. These tests take a picture of your insides. Looking at these pictures, your doctor will be able to tell whether ... Safety Injury Rehabilitation Emotional Well-Being Mental Health Sex and Birth Control Sex and Sexuality Birth Control ...

A 25-kW Series-Resonant Power Converter

NASA Technical Reports Server (NTRS)

Frye, R. J.; Robson, R. R.

1986-01-01

Prototype exhibited efficiency of 93.9 percent. 25-kW resonant dc/dc power converter designed, developed, fabricated, and tested, using Westinghouse D7ST transistors as high-power switches. D7ST transistor characterized for use as switch in series-resonant converters, and refined base-drive circuit developed. Technical base includes advanced switching magnetic, and filter components, mathematical circuit models, control philosophies, and switch-drive strategies. Power-system benefits such as lower losses when used for high-voltage distribution, and reduced magnetics and filter mass realized.

Bidirectional power converter control electronics

NASA Technical Reports Server (NTRS)

Mildice, J. W.

1987-01-01

The object of this program was to design, build, test, and deliver a set of control electronics suitable for control of bidirectional resonant power processing equipment of the direct output type. The program is described, including the technical background, and results discussed. Even though the initial program tested only the logic outputs, the hardware was subsequently tested with high-power breadboard equipment, and in the testbed of NASA contract NAS3-24399. The completed equipment is now operating as part of the Space Station Power System Test Facility at NASA Lewis Research Center.

SPIN-COSY: Spin-Manipulating Polarized Deuterons and Protons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leonova, M. A.; Chao, A. W.; Krisch, A. D.

2009-08-04

We studied spin manipulation of 1.85 GeV/c polarized deuteron beam stored in COSY obtaining a spin-flip efficiency of 97{+-}1%. We first discovered experimentally and then explained theoretically interesting behavior of the deuteron tensor polarization. We, for the first time, studied systematically spin resonance strengths induced by rf dipoles and solenoids. We found huge disagreements between the strengths measured in controlled Froissart-Stora sweeps and the theoretical values calculated using the well-known formulae. These data instigated re-examination of these formulae. We tested Chao's proposed new matrix formalism for describing the spin dynamics due to a single spin resonance, which may be themore » first fundamental improvement of the Froissart-Stora equation in that it allows analytic calculation of the beam polarization's behavior inside a resonance. Our measurements of the deuteron's polarization near and inside the resonance agreed precisely with the Chao formalism's predicted oscillations. We tested Kondratenko's proposal to overcome depolarizing resonances by ramping through them with a crossing pattern, which should force the depolarizing contributions to cancel themselves. Our first test of this idea with 2.1 GeV/c protons was not conclusive but a later test with 1.85 GeV/c deuterons demonstrated a rather substantial reduction in the depolarization compared to the tune jump at the same rate.« less

Biotin-Streptavidin Binding Interactions of Dielectric Filled Silicon Bulk Acoustic Resonators for Smart Label-Free Biochemical Sensor Applications

PubMed Central

Heidari, Amir; Yoon, Yong-Jin; Park, Woo-Tae; Su, Pei-Chen; Miao, Jianmin; Lin, Julius Tsai Ming; Park, Mi Kyoung

2014-01-01

Sensor performance of a dielectric filled silicon bulk acoustic resonator type label-free biosensor is verified with biotin-streptavidin binding interactions as a model system. The mass sensor is a micromachined silicon square plate with a dielectric filled capacitive excitation mechanism. The resonance frequency of the biotin modified resonator decreased 315 ppm when exposed to streptavidin solution for 15 min with a concentration of 10−7 M, corresponding to an added mass of 3.43 ng on the resonator surface. An additional control is added by exposing a bovine serum albumin (BSA)-covered device to streptavidin in the absence of the attached biotin. No resonance frequency shift was observed in the control experiment, which confirms the specificity of the detection. The sensor-to-sensor variability is also measured to be 4.3%. Consequently, the developed sensor can be used to observe in biotin-streptavidin interaction without the use of labelling or molecular tags. In addition, biosensor can be used in a variety of different immunoassay tests. PMID:24608003

Power processor for a 20CM ion thruster

NASA Technical Reports Server (NTRS)

Biess, J. J.; Schoenfeld, A. D.; Cohen, E.

1973-01-01

A power processor breadboard for the JPL 20CM Ion Engine was designed, fabricated, and tested to determine compliance with the electrical specification. The power processor breadboard used the silicon-controlled rectifier (SCR) series resonant inverter as the basic power stage to process all the power to the ion engine. The breadboard power processor was integrated with the JPL 20CM ion engine and complete testing was performed. The integration tests were performed without any silicon-controlled rectifier failure. This demonstrated the ruggedness of the series resonant inverter in protecting the switching elements during arcing in the ion engine. A method of fault clearing the ion engine and returning back to normal operation without elaborate sequencing and timing control logic was evolved. In this method, the main vaporizer was turned off and the discharge current limit was reduced when an overload existed on the screen/accelerator supply. After the high voltage returned to normal, both the main vaporizer and the discharge were returned to normal.

Different Plasticity Patterns of Language Function in Children With Perinatal and Childhood Stroke

PubMed Central

Tomberg, Tiiu; Kepler, Joosep; Laugesaar, Rael; Kaldoja, Mari-Liis; Kepler, Kalle; Kolk, Anneli

2014-01-01

Plasticity of language function after brain damage can depend on maturation of the brain. Children with left-hemisphere perinatal (n = 7) or childhood stroke (n = 5) and 12 controls were investigated using functional magnetic resonance imaging. The verb generation and the sentence comprehension tasks were employed to activate the expressive and receptive language areas, respectively. Weighted laterality indices were calculated and correlated with results assessed by neuropsychological test battery. Compared to controls, children with childhood stroke showed significantly lower mean scores for the expressive (P < .05) and receptive (P = .05) language tests. On functional magnetic resonance imaging they showed left-side cortical activation, as did controls. Perinatal stroke patients showed atypical right-side or bilateral language lateralization during both tasks. Negative correlation for stroke patients was found between scores for expressive language tests and laterality index during the verb generation task. (Re)organization of language function differs in children with perinatal and childhood stroke and correlates with neurocognitive performance. PMID:23748202

Testing the quality of images for permanent magnet desktop MRI systems using specially designed phantoms.

PubMed

Qiu, Jianfeng; Wang, Guozhu; Min, Jiao; Wang, Xiaoyan; Wang, Pengcheng

2013-12-21

Our aim was to measure the performance of desktop magnetic resonance imaging (MRI) systems using specially designed phantoms, by testing imaging parameters and analysing the imaging quality. We designed multifunction phantoms with diameters of 18 and 60 mm for desktop MRI scanners in accordance with the American Association of Physicists in Medicine (AAPM) report no. 28. We scanned the phantoms with three permanent magnet 0.5 T desktop MRI systems, measured the MRI image parameters, and analysed imaging quality by comparing the data with the AAPM criteria and Chinese national standards. Image parameters included: resonance frequency, high contrast spatial resolution, low contrast object detectability, slice thickness, geometrical distortion, signal-to-noise ratio (SNR), and image uniformity. The image parameters of three desktop MRI machines could be measured using our specially designed phantoms, and most parameters were in line with MRI quality control criterion, including: resonance frequency, high contrast spatial resolution, low contrast object detectability, slice thickness, geometrical distortion, image uniformity and slice position accuracy. However, SNR was significantly lower than in some references. The imaging test and quality control are necessary for desktop MRI systems, and should be performed with the applicable phantom and corresponding standards.

Texture Analysis of T1-Weighted and Fluid-Attenuated Inversion Recovery Images Detects Abnormalities That Correlate With Cognitive Decline in Small Vessel Disease.

PubMed

Tozer, Daniel J; Zeestraten, Eva; Lawrence, Andrew J; Barrick, Thomas R; Markus, Hugh S

2018-06-04

Magnetic resonance imaging may be useful to assess disease severity in cerebral small vessel disease (SVD), identify those individuals who are most likely to progress to dementia, monitor disease progression, and act as surrogate markers to test new therapies. Texture analysis extracts information on the relationship between signal intensities of neighboring voxels. A potential advantage over techniques, such as diffusion tensor imaging, is that it can be used on clinically obtained magnetic resonance sequences. We determined whether texture parameters (TP) were abnormal in SVD, correlated with cognitive impairment, predicted cognitive decline, or conversion to dementia. In the prospective SCANS study (St George's Cognition and Neuroimaging in Stroke), we assessed TP in 121 individuals with symptomatic SVD at baseline, 99 of whom attended annual cognitive testing for 5 years. Conversion to dementia was recorded for all subjects during the 5-year period. Texture analysis was performed on fluid-attenuated inversion recovery and T1-weighted images. The TP obtained from the SVD cohort were cross-sectionally compared with 54 age-matched controls scanned on the same magnetic resonance imaging system. There were highly significant differences in several TP between SVD cases and controls. Within the SVD population, TP were highly correlated to other magnetic resonance imaging parameters (brain volume, white matter lesion volume, lacune count). TP correlated with executive function and global function at baseline and predicted conversion to dementia, after controlling for age, sex, premorbid intelligence quotient, and magnetic resonance parameters. TP, which can be obtained from routine clinical images, are abnormal in SVD, and the degree of abnormality correlates with executive dysfunction and global cognition at baseline and decline during 5 years. TP may be useful to assess disease severity in clinically collected data. This needs testing in data clinically acquired across multiple sites. © 2018 The Authors.

[Magnetic resonance spectroscopy in lenticular nucleus of Bipolar II disorder and its relation with cognitive function].

PubMed

Zhang, Haiyan; Wen, Shenglin; Wang, Jihui; Cheng, Minfeng; Wang, Hong

2015-03-10

To explore the magnetic resonance spectroscopy characteristics of lenticular nucleus in Bipolar II disorder and its relation with cognitive function. Thirty Bipolar II disorder patients in hospital from 2012 September to 2013 April and twenty healthy controls were evaluated with Multi-Voxel 1H-MRS scans on lenticular nucleus to assess the NAA, Cho, Cr and MI. All subjects were assessed for attention using the Stroop Test and executive function by Wisconsin card sorting test. NAA, Cho, Cr in right lenticular nucleus and Cr in left lenticular nucleus were lower than healthy controls (P < 0.05). The patients showed significant cognitive impairment in all aspects of Stroop Test and Wisconsin card sorting test (P < 0.05). NAA in right lenticular nucleus was positively correlated with correct number of Stroop-CW. Neural dysfunction in right lenticular nucleus of Bipolar II disorder may influence attention function. Cellular energy metabolism rate was reduced in bilateral lenticular nucleus.

Anomalous Thrust Production from an RF Test Device Measured on a Low-Thrust Torsion Pendulum

NASA Technical Reports Server (NTRS)

Brady, David; White, Harold G.; March, Paul; Lawrence, James T.; Davies, Frank J.

2014-01-01

This paper describes the eight-day August 2013 test campaign designed to investigate and demonstrate viability of using classical magnetoplasmadynamics to obtain a propulsive momentum transfer via the quantum vacuum virtual plasma. This paper will not address the physics of the quantum vacuum plasma thruster, but instead will describe the test integration, test operations, and the results obtained from the test campaign. Approximately 30-50 micro-Newtons of thrust were recorded from an electric propulsion test article consisting primarily of a radio frequency (RF) resonant cavity excited at approximately 935 megahertz. Testing was performed on a low-thrust torsion pendulum that is capable of detecting force at a single-digit micronewton level, within a stainless steel vacuum chamber with the door closed but at ambient atmospheric pressure. Several different test configurations were used, including two different test articles as well as a reversal of the test article orientation. In addition, the test article was replaced by an RF load to verify that the force was not being generated by effects not associated with the test article. The two test articles were designed by Cannae LLC of Doylestown, Pennsylvania. The torsion pendulum was designed, built, and operated by Eagleworks Laboratories at the NASA Johnson Space Center of Houston, Texas. Approximately six days of test integration were required, followed by two days of test operations, during which, technical issues were discovered and resolved. Integration of the two test articles and their supporting equipment was performed in an iterative fashion between the test bench and the vacuum chamber. In other words, the test article was tested on the bench, then moved to the chamber, then moved back as needed to resolve issues. Manual frequency control was required throughout the test. Thrust was observed on both test articles, even though one of the test articles was designed with the expectation that it would not produce thrust. Specifically, one test article contained internal physical modifications that were designed to produce thrust, while the other did not (with the latter being referred to as the "null" test article). Test data gathered includes torsion pendulum displacement measurements which are used to calculate generated force, still imagery in the visible spectrum to document the physical configuration, still imagery in the infrared spectrum to characterize the thermal environment, and video imagery. Post-test data includes static and animated graphics produced during RF resonant cavity characterization using the COMSOL Multiphysics® software application. Excerpts from all of the above are included and discussed in this paper. Lessons learned from test integration and operations include identification of the need to replace manual control of the resonant cavity target frequency with an automated frequency control capability. Future test plans include the development of an automatic frequency control circuit. Test results indicate that the RF resonant cavity thruster design, which is unique as an electric propulsion device, is producing a force that is not attributable to any classical electromagnetic phenomenon and therefore is potentially demonstrating an interaction with the quantum vacuum virtual plasma. Future test plans include independent verification and validation at other test facilities.

Resonance test system

DOEpatents

Musial, Walter [Boulder, CO; White, Darris [Superior, CO

2011-05-31

An apparatus (10) for applying at least one load to a specimen (12) according to one embodiment of the invention may comprise a mass (18). An actuator (20) mounted to the specimen (12) and operatively associated with the mass (18) moves the mass (18) along a linear displacement path (22) that is perpendicular to a longitudinal axis of the specimen (12). A control system (26) operatively associated with the actuator (20) operates the actuator (20) to reciprocate the mass (18) along the linear displacement path (22) at a reciprocating frequency, the reciprocating frequency being about equal to a resonance frequency of the specimen (12) in a test configuration.

Traumatic Brain Injury Diffusion Magnetic Resonance Imaging Research Roadmap Development Project

DTIC Science & Technology

2011-10-01

promising technology on the horizon is the Diffusion Tensor Imaging ( DTI ). Diffusion tensor imaging ( DTI ) is a magnetic resonance imaging (MRI)-based...in the brain. The potential for DTI to improve our understanding of TBI has not been fully explored and challenges associated with non-existent...processing tools, quality control standards, and a shared image repository. The recommendations will be disseminated and pilot tested. A DTI of TBI

Observation and Control of Hamiltonian Chaos in Wave-particle Interaction

NASA Astrophysics Data System (ADS)

Doveil, F.; Elskens, Y.; Ruzzon, A.

2010-11-01

Wave-particle interactions are central in plasma physics. The paradigm beam-plasma system can be advantageously replaced by a traveling wave tube (TWT) to allow their study in a much less noisy environment. This led to detailed analysis of the self-consistent interaction between unstable waves and an either cold or warm electron beam. More recently a test cold beam has been used to observe its interaction with externally excited wave(s). This allowed observing the main features of Hamiltonian chaos and testing a new method to efficiently channel chaotic transport in phase space. To simulate accurately and efficiently the particle dynamics in the TWT and other 1D particle-wave systems, a new symplectic, symmetric, second order numerical algorithm is developed, using particle position as the independent variable, with a fixed spatial step. This contribution reviews : presentation of the TWT and its connection to plasma physics, resonant interaction of a charged particle in electrostatic waves, observation of particle trapping and transition to chaos, test of control of chaos, and description of the simulation algorithm. The velocity distribution function of the electron beam is recorded with a trochoidal energy analyzer at the output of the TWT. An arbitrary waveform generator is used to launch a prescribed spectrum of waves along the 4m long helix of the TWT. The nonlinear synchronization of particles by a single wave, responsible for Landau damping, is observed. We explore the resonant velocity domain associated with a single wave as well as the transition to large scale chaos when the resonant domains of two waves and their secondary resonances overlap. This transition exhibits a devil's staircase behavior when increasing the excitation level in agreement with numerical simulation. A new strategy for control of chaos by building barriers of transport in phase space as well as its robustness is successfully tested. The underlying concepts extend far beyond the field of electron devices and plasma physics.

Executive dysfunctions in migraine with and without aura: what is the role of white matter lesions?

PubMed

Le Pira, Francesco; Reggio, Ester; Quattrocchi, Graziella; Sanfilippo, Cristina; Maci, Tiziana; Cavallaro, Tiziana; Zappia, Mario

2014-01-01

Executive dysfunctions and white matter lesions on magnetic resonance imaging have been reported in migraine. The aim of this study was to determine whether any correlation between these 2 variables exists. Forty-four subjects affected by migraine with or without aura were compared with 16 healthy subjects. A battery of neuropsychological tests assessing executive functions was administered to all subjects. Number and total volume of white matter lesions were assessed in the whole brain and in the frontal lobe. The performances of both groups of migraineurs, with and without aura, were significantly worse when compared with controls on Boston Scanning Test. Moreover, we found lower performances compared with controls respectively on Frontal Assessment Battery in patients with migraine with aura and on Controlled Oral Word Association Test in patients with migraine without aura. Nineteen patients (43.2%) and one control subject (6.2%) had white matter lesions. We did not find any significant correlation between white matter lesions load and neuropsychological performances. On the basis of our results, white matter lesions load on magnetic resonance imaging do not seem to contribute to neuropsychological performances deficit in migraineurs. © 2013 American Headache Society.

Passivation of pigment particles for thermal control coatings

NASA Technical Reports Server (NTRS)

Sancier, K. M.; Morrison, S. R.; Farley, E. P.

1975-01-01

The preparation of a matrix of 48 samples consisting of pigments and pigmented paints is described. The results obtained from testing these samples by electron spin resonance and by in situ spectral reflectance measurements in space simulation tests are presented. Conclusions and recommendations for further research are given.

Evaluation of the New B-REX Fatigue Testing System for Multi-Megawatt Wind Turbine Blades: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, D.; Musial, W.; Engberg, S.

2004-12-01

The National Renewable Energy Laboratory (NREL) recently developed a new hybrid fatigue testing system called the Blade Resonance Excitation (B-REX) test system. The new system uses 65% less energy to test large wind turbine blades in half the time of NREL's dual-axis forced-displacement test method with lower equipment and operating costs. The B-REX is a dual-axis test system that combines resonance excitation with forced hydraulic loading to reduce the total test time required while representing the operating strains on the critical inboard blade stations more accurately than a single-axis test system. The analysis and testing required to fully implement themore » B-REX was significant. To control unanticipated blade motion and vibrations caused by dynamic coupling between the flap, lead-lag, and torsional directions, we needed to incorporate additional test hardware and control software. We evaluated the B-REX test system under stable operating conditions using a combination of various sensors. We then compared our results with results from the same blade, tested previously using NREL's dual-axis forced-displacement test method. Experimental results indicate that strain levels produced by the B-REX system accurately replicated the forced-displacement method. This paper describes the challenges we encountered while developing the new blade fatigue test system and the experimental results that validate its accuracy.« less

Resonant mode controllers for launch vehicle applications

NASA Technical Reports Server (NTRS)

Schreiner, Ken E.; Roth, Mary Ellen

1992-01-01

Electro-mechanical actuator (EMA) systems are currently being investigated for the National Launch System (NLS) as a replacement for hydraulic actuators due to the large amount of manpower and support hardware required to maintain the hydraulic systems. EMA systems in weight sensitive applications, such as launch vehicles, have been limited to around 5 hp due to system size, controller efficiency, thermal management, and battery size. Presented here are design and test data for an EMA system that competes favorably in weight and is superior in maintainability to the hydraulic system. An EMA system uses dc power provided by a high energy density bipolar lithium thionyl chloride battery, with power conversion performed by low loss resonant topologies, and a high efficiency induction motor controlled with a high performance field oriented controller to drive a linear actuator.

Optimizing the feedback control of Galvo scanners for laser manufacturing systems

NASA Astrophysics Data System (ADS)

Mirtchev, Theodore; Weeks, Robert; Minko, Sergey

2010-06-01

This paper summarizes the factors that limit the performance of moving-magnet galvo scanners driven by closed-loop digital servo amplifiers: torsional resonances, drifts, nonlinearities, feedback noise and friction. Then it describes a detailed Simulink® simulator that takes into account these factors and can be used to automatically tune the controller for best results with given galvo type and trajectory patterns. It allows for rapid testing of different control schemes, for instance combined position/velocity PID loops and displays the corresponding output in terms of torque, angular position and feedback sensor signal. The tool is configurable and can either use a dynamical state-space model of galvo's open-loop response, or can import the experimentally measured frequency domain transfer function. Next a drive signal digital pre-filtering technique is discussed. By performing a real-time Fourier analysis of the raw command signal it can be pre-warped to minimize all harmonics around the torsional resonances while boosting other non-resonant high frequencies. The optimized waveform results in much smaller overshoot and better settling time. Similar performance gain cannot be extracted from the servo controller alone.

A 1-2 GHz pulsed and continuous wave electron paramagnetic resonance spectrometer

NASA Astrophysics Data System (ADS)

Quine, Richard W.; Rinard, George A.; Ghim, Barnard T.; Eaton, Sandra S.; Eaton, Gareth R.

1996-07-01

A microwave bridge has been constructed that performs three types of electron paramagnetic resonance experiments: continuous wave, pulsed saturation recovery, and pulsed electron spin echo. Switching between experiment types can be accomplished via front-panel switches without moving the sample. Design features and performance of the bridge and of a resonator used in testing the bridge are described. The bridge is constructed of coaxial components connected with semirigid cable. Particular attention has been paid to low-noise design of the preamplifier and stability of automatic frequency control circuits. The bridge incorporates a Smith chart display and phase adjustment meter for ease of tuning.

Longitudinal Evaluation of Muscle Composition Using Magnetic Resonance in 4 Boys With Duchenne Muscular Dystrophy: Case Series.

PubMed

Senesac, Claudia R; Lott, Donovan J; Forbes, Sean C; Mathur, Sunita; Arpan, Ishu; Senesac, Emily S; Walter, Glenn A; Vandenborne, Krista

2015-07-01

Duchenne muscular dystrophy (DMD), an inherited recessive X chromosome-linked disease, is the most severe childhood form of muscular dystrophy. Boys with DMD experience muscle loss, with infiltration of intramuscular fat into muscles. This case series describes the progression of DMD in boys using magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS). Magnetic resonance results are then compared with an established functional timed test. Four boys with DMD and 4 healthy age-matched controls were chosen from a larger cohort. Boys with DMD were assessed at 4 time points over 2 years, with controls assessed at baseline only. Progression of the disease was documented by assessing the plantar flexors using MRI and MRS techniques and by assessing ambulation using the 30-Foot Fast Walk Test. Transverse relaxation time (T2) values were elevated in all boys with DMD at baseline. The lipid ratio increased rapidly as the disease progressed in 2 boys. Discrete changes in T2 in the other 2 boys with DMD indicated a slower disease progression. Magnetic resonance imaging and MRS allowed monitoring of the disease over all time periods regardless of ambulation status. The magnetic resonance data were collected with 2 different magnets at 2 different field strengths (1.5 and 3.0 T). Although we corrected for this difference, care must be taken in interpreting data when different image collection systems are used. This was a case series of 4 boys with DMD taken from a larger cohort study. Magnetic resonance imaging and MRS are objective, noninvasive techniques for measuring muscle pathology and can be used to detect discrete changes in both people who are ambulatory and those who are nonambulatory. These techniques should be considered when monitoring DMD progression and assessing efficacy of therapeutic interventions. © 2015 American Physical Therapy Association.

Longitudinal Evaluation of Muscle Composition Using Magnetic Resonance in 4 Boys With Duchenne Muscular Dystrophy: Case Series

PubMed Central

Lott, Donovan J.; Forbes, Sean C.; Mathur, Sunita; Arpan, Ishu; Senesac, Emily S.; Walter, Glenn A.; Vandenborne, Krista

2015-01-01

Background Duchenne muscular dystrophy (DMD), an inherited recessive X chromosome-linked disease, is the most severe childhood form of muscular dystrophy. Boys with DMD experience muscle loss, with infiltration of intramuscular fat into muscles. Objectives This case series describes the progression of DMD in boys using magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS). Magnetic resonance results are then compared with an established functional timed test. Methods Four boys with DMD and 4 healthy age-matched controls were chosen from a larger cohort. Boys with DMD were assessed at 4 time points over 2 years, with controls assessed at baseline only. Progression of the disease was documented by assessing the plantar flexors using MRI and MRS techniques and by assessing ambulation using the 30-Foot Fast Walk Test. Results Transverse relaxation time (T2) values were elevated in all boys with DMD at baseline. The lipid ratio increased rapidly as the disease progressed in 2 boys. Discrete changes in T2 in the other 2 boys with DMD indicated a slower disease progression. Magnetic resonance imaging and MRS allowed monitoring of the disease over all time periods regardless of ambulation status. Limitations The magnetic resonance data were collected with 2 different magnets at 2 different field strengths (1.5 and 3.0 T). Although we corrected for this difference, care must be taken in interpreting data when different image collection systems are used. This was a case series of 4 boys with DMD taken from a larger cohort study. Conclusions Magnetic resonance imaging and MRS are objective, noninvasive techniques for measuring muscle pathology and can be used to detect discrete changes in both people who are ambulatory and those who are nonambulatory. These techniques should be considered when monitoring DMD progression and assessing efficacy of therapeutic interventions. PMID:25592189

Development and testing of cabin sidewall acoustic resonators for the reduction of cabin tone levels in propfan-powered aircraft

NASA Technical Reports Server (NTRS)

Kuntz, H. L.; Gatineau, R. J.; Prydz, R. A.; Balena, F. J.

1991-01-01

The use of Helmholtz resonators to increase the sidewall transmission loss (TL) in aircraft cabin sidewalls is evaluated. Development, construction, and test of an aircraft cabin acoustic enclosure, built in support of the Propfan Test Assessment (PTA) program, is described. Laboratory and flight test results are discussed. Resonators (448) were located between the enclosure trim panels and the fuselage shell. In addition, 152 resonators were placed between the enclosure and aircraft floors. The 600 resonators were each tuned to a propfan fundamental blade passage frequency (235 Hz). After flight testing on the PTA aircraft, noise reduction (NR) tests were performed with the enclosure in the Kelly Johnson Research and Development Center Acoustics Laboratory. Broadband and tonal excitations were used in the laboratory. Tonal excitation simulated the propfan flight test excitation. The resonators increase the NR of the cabin walls around the resonance frequency of the resonator array. Increases in NR of up to 11 dB were measured. The effects of flanking, sidewall absorption, cabin absorption, resonator loading of trim panels, and panel vibrations are presented. Resonator and sidewall panel design and test are discussed.

A novel method to optimize the mode spectrum of the dynamic resonant magnetic perturbation on the J-TEXT tokamak.

PubMed

Yi, B; Rao, B; Ding, Y H; Li, M; Xu, H Y; Zhang, M; Zhuang, G; Pan, Y

2014-11-01

The dynamic resonant magnetic perturbation (DRMP) system has been developed for the J-TEXT tokamak to study the interaction between the rotating perturbation magnetic field and the plasma. When the DRMP coils are energized by two phase sinusoidal currents with the same frequency, a 2/1 rotating resonant magnetic perturbation component will be generated. But at the same time, a small perturbation component rotating in the opposite direction is also produced because of the control error of the currents. This small component has bad influence on the experiment investigations. Actually, the mode spectrum of the generated DRMP can be optimized with an accurate control of phase difference between the two currents. In this paper, a new phase control method based on a novel all-digital phase-locked loop (ADPLL) is proposed. The proposed method features accurate phase control and flexible phase adjustment. Modeling and analysis of the proposed ADPLL is presented to guide the design of the parameters of the phase controller in order to obtain a better performance. Testing results verify the effectiveness of the ADPLL and validity of the method applying to the DRMP system.

A novel method to optimize the mode spectrum of the dynamic resonant magnetic perturbation on the J-TEXT tokamak

NASA Astrophysics Data System (ADS)

Yi, B.; Rao, B.; Ding, Y. H.; Li, M.; Xu, H. Y.; Zhang, M.; Zhuang, G.; Pan, Y.

2014-11-01

The dynamic resonant magnetic perturbation (DRMP) system has been developed for the J-TEXT tokamak to study the interaction between the rotating perturbation magnetic field and the plasma. When the DRMP coils are energized by two phase sinusoidal currents with the same frequency, a 2/1 rotating resonant magnetic perturbation component will be generated. But at the same time, a small perturbation component rotating in the opposite direction is also produced because of the control error of the currents. This small component has bad influence on the experiment investigations. Actually, the mode spectrum of the generated DRMP can be optimized with an accurate control of phase difference between the two currents. In this paper, a new phase control method based on a novel all-digital phase-locked loop (ADPLL) is proposed. The proposed method features accurate phase control and flexible phase adjustment. Modeling and analysis of the proposed ADPLL is presented to guide the design of the parameters of the phase controller in order to obtain a better performance. Testing results verify the effectiveness of the ADPLL and validity of the method applying to the DRMP system.

Vibration Control of Deployable Astromast Boom: Preliminary Experiments

NASA Technical Reports Server (NTRS)

Swaminadham, M.; Hamilton, David A.

1994-01-01

This paper deals with the dynamic characterization of a flexible aerospace solar boom. The modeling issues and sine dwell vibration testing to determine natural frequencies and mode shapes of a continuous-longer on deployable ASTROMAST lattice boom are discussed. The details of the proof-of-concept piezoelectric active vibration experiments on a simple cantilever beam to control its vibrations are presented. The control parameters like voltage to the controller crystal and its location are investigated, to determine the effectiveness of control element to suppress selected resonant vibrations of the test specimen. Details of this experiment and plans for its future adaptation to the prototype structure are also discussed.

Active vibration control for flexible rotor by optimal direct-output feedback control

NASA Technical Reports Server (NTRS)

Nonami, Kenzou; Dirusso, Eliseo; Fleming, David P.

1989-01-01

Experimental research tests were performed to actively control the rotor vibrations of a flexible rotor mounted on flexible bearing supports. The active control method used in the tests is called optimal direct-output feedback control. This method uses four electrodynamic actuators to apply control forces directly to the bearing housings in order to achieve effective vibration control of the rotor. The force actuators are controlled by an analog controller that accepts rotor displacement as input. The controller is programmed with experimentally determined feedback coefficients; the output is a control signal to the force actuators. The tests showed that this active control method reduced the rotor resonance peaks due to unbalance from approximately 250 micrometers down to approximately 25 micrometers (essentially runout level). The tests were conducted over a speed range from 0 to 10,000 rpm; the rotor system had nine critical speeds within this speed range. The method was effective in significantly reducing the rotor vibration for all of the vibration modes and critical speeds.

Active vibration control for flexible rotor by optimal direct-output feedback control

NASA Technical Reports Server (NTRS)

Nonami, K.; Dirusso, E.; Fleming, D. P.

1989-01-01

Experimental research tests were performed to actively control the rotor vibrations of a flexible rotor mounted on flexible bearing supports. The active control method used in the tests is called optimal direct-output feedback control. This method uses four electrodynamic actuators to apply control forces directly to the bearing housings in order to achieve effective vibration control of the rotor. The force actuators are controlled by an analog controller that accepts rotor displacement as input. The controller is programmed with experimentally determined feedback coefficients; the output is a control signal to the force actuators. The tests showed that this active control method reduced the rotor resonance peaks due to unbalance from approximately 250 microns down to approximately 25 microns (essentially runout level). The tests were conducted over a speed range from 0 to 10,000 rpm; the rotor system had nine critical speeds within this speed range. The method was effective in significantly reducing the rotor vibration for all of the vibration modes and critical speeds.

46 CFR 162.060-30 - Testing requirements for ballast water management system (BWMS) components.

Code of Federal Regulations, 2013 CFR

2013-10-01

... production configuration: (1) A resonance search vertically up and down, horizontally from side to side, and...) Components that may be installed in enclosed spaces that are environmentally controlled, including an engine...

46 CFR 162.060-30 - Testing requirements for ballast water management system (BWMS) components.

Code of Federal Regulations, 2014 CFR

2014-10-01

... production configuration: (1) A resonance search vertically up and down, horizontally from side to side, and...) Components that may be installed in enclosed spaces that are environmentally controlled, including an engine...

Magnetic resonance spectroscopy study of the glutamatergic system in adolescent males with high-functioning autistic disorder: a pilot study at 4T.

PubMed

Joshi, Gagan; Biederman, Joseph; Wozniak, Janet; Goldin, Rachel L; Crowley, Dave; Furtak, Stephannie; Lukas, Scott E; Gönenç, Atilla

2013-08-01

The pilot study aimed at examining the neural glutamatergic activity in autism. Seven adolescent males (mean age: 14 ± 1.8; age range: 12-17 years) with intact intellectual capacity (mean IQ: 108 ± 14.26; IQ range: 85-127) suffering from autistic disorder and an equal number of age- and sex-matched healthy controls underwent a two-dimensional magnetic resonance spectroscopy scan at 4T. Results indicated significantly high glutamate (Glu) levels in the anterior cingulate cortex of autistic disorder versus control subjects (paired t test p = 0.01) and a trend for lower Glu in the right medial temporal lobe, which was not statistically different between the groups (paired t test p = 0.06). These preliminary findings support the glutamatergic dysregulation hypothesis in autism and need to be replicated in a larger sample.

Design and testing of a 750MHz CW-EPR digital console for small animal imaging.

PubMed

Sato-Akaba, Hideo; Emoto, Miho C; Hirata, Hiroshi; Fujii, Hirotada G

2017-11-01

This paper describes the development of a digital console for three-dimensional (3D) continuous wave electron paramagnetic resonance (CW-EPR) imaging of a small animal to improve the signal-to-noise ratio and lower the cost of the EPR imaging system. A RF generation board, an RF acquisition board and a digital signal processing (DSP) & control board were built for the digital EPR detection. Direct sampling of the reflected RF signal from a resonator (approximately 750MHz), which contains the EPR signal, was carried out using a band-pass subsampling method. A direct automatic control system to reduce the reflection from the resonator was proposed and implemented in the digital EPR detection scheme. All DSP tasks were carried out in field programmable gate array ICs. In vivo 3D imaging of nitroxyl radicals in a mouse's head was successfully performed. Copyright © 2017 Elsevier Inc. All rights reserved.

Design and testing of a 750 MHz CW-EPR digital console for small animal imaging

NASA Astrophysics Data System (ADS)

Sato-Akaba, Hideo; Emoto, Miho C.; Hirata, Hiroshi; Fujii, Hirotada G.

2017-11-01

This paper describes the development of a digital console for three-dimensional (3D) continuous wave electron paramagnetic resonance (CW-EPR) imaging of a small animal to improve the signal-to-noise ratio and lower the cost of the EPR imaging system. A RF generation board, an RF acquisition board and a digital signal processing (DSP) & control board were built for the digital EPR detection. Direct sampling of the reflected RF signal from a resonator (approximately 750 MHz), which contains the EPR signal, was carried out using a band-pass subsampling method. A direct automatic control system to reduce the reflection from the resonator was proposed and implemented in the digital EPR detection scheme. All DSP tasks were carried out in field programmable gate array ICs. In vivo 3D imaging of nitroxyl radicals in a mouse's head was successfully performed.

Determination of mechanical properties of battery films from acoustic resonances

NASA Astrophysics Data System (ADS)

Dallon, Kathryn L.; Yao, Jing; Wheeler, Dean R.; Mazzeo, Brian A.

2018-04-01

Measuring the mechanical properties of lithium-ion battery films, such as thickness and elasticity, is important for predicting and improving homogeneity of the films and subsequent performance of the battery. Problems with film heterogeneity could be identified and addressed early on through accurate, non-destructive inspection of the electrode as it is being manufactured. This research investigates the use of acoustic measurements as an alternative means of non-destructive quality control that could be adapted for on-line use. Here we report on our efforts to distinguish among films with different mechanical properties using acoustic resonances. A clamped film is excited using a pulsed infrared laser to produce an acoustic resonance in a confined area, and a microphone measures the acoustic response. Because the resonance depends on properties such as thickness and density, the resonance frequency shifts with changes in these properties. As the thickness increases, the resonance frequency decreases. These results show that acoustic tests can demonstrate observable differences between films with different properties.

High precision single qubit tuning via thermo-magnetic field control

NASA Astrophysics Data System (ADS)

Broadway, David A.; Lillie, Scott E.; Dontschuk, Nikolai; Stacey, Alastair; Hall, Liam T.; Tetienne, Jean-Philippe; Hollenberg, Lloyd C. L.

2018-03-01

Precise control of the resonant frequency of a spin qubit is of fundamental importance to quantum sensing protocols. We demonstrate a control technique on a single nitrogen-vacancy (NV) centre in diamond where the applied magnetic field is modified by fine-tuning a permanent magnet's magnetisation via temperature control. Through this control mechanism, nanoscale cross-relaxation spectroscopy of both electron and nuclear spins in the vicinity of the NV centre is performed. We then show that through maintaining the magnet at a constant temperature, an order of magnitude improvement in the stability of the NV qubit frequency can be achieved. This improved stability is tested in the polarisation of a small ensemble of nearby 13C spins via resonant cross-relaxation, and the lifetime of this polarisation explored. The effectiveness and relative simplicity of this technique may find use in the realisation of portable spectroscopy and/or hyperpolarisation systems.

Electro-Mechanical Actuator. DC Resonant Link Controller

NASA Technical Reports Server (NTRS)

Schreiner, Kenneth E.

1996-01-01

This report summarizes the work performed on the 68 HP electro-mechanical actuator (EMA) system developed on NASA contract for the Electrical Actuation (ELA) Technology Bridging Program. The system was designed to demonstrate the capability of large, high power linear ELAs for applications such as Thrust Vector Control (TVC) on rocket engines. It consists of a motor controller, drive electronics and a linear actuator capable of up to 32,00 lbs loading at 7.4 inches/second. The drive electronics are based on the Resonant DC link concept and operate at a nominal frequency of 55 kHz. The induction motor is a specially designed high speed, low inertia motor capable of a 68 peak HP. The actuator was originally designed by MOOG Aerospace under an internal R & D program to meet Space Shuttle Main Engine (SSME) TVC requirements. The design was modified to meet this programs linear rate specification of 7.4 inches/second. The motor and driver were tested on a dynamometer at the Martin Marietta Space Systems facility. System frequency response, step response and force-velocity tests were conducted at the MOOG Aerospace facility. A complete description of the system and all test results can be found in the body of the report.

Neurocognitive dysfunction in children with β thalassemia major: psychometric, neurophysiologic and radiologic evaluation.

PubMed

Elalfy, M S; Aly, R H; Azzam, H; Aboelftouh, K; Shatla, R H; Tarif, M; Abdatty, M; Elsayed, R M

2017-12-01

To evaluate the impact of iron chelating drugs and serum ferritin on the neurocognitive functions of patients with β thalassemia major (β-TM), using psychometric, neurophysiologic and radiologic tests. Eighty children with β-TM were enrolled into the study and were compared to 40 healthy controls. All participants were evaluated by measuring serum ferritin, neurocognitive assessment by Benton Visual Retention Test, Wechsler Intelligence Scale for Children, Wisconsin Card Sort Test, P300 and magnetic resonance spectroscopy (MRS). WISC in our study showed that 40% of cases were borderline mental function as regards total IQ. Neurophysiologic tests were significantly impaired in patients compared to control group, with significant impairment in those receiving desferrioxamine (DFO). P300 amplitude was significantly lower in cases compared to controls (2.24 and 4.66 uv, respectively), recording the shortest amplitude in patients receiving DFO. Altered metabolic markers in the brain were detected by MRS in the form of reduced N-acetylaspartate to creatine ratio in 78.3% of our cases. There were significant correlations between psychometric tests and both neurophysiologic (P300) and radiologic (MRS) tests. β-TM is associated with neurocognitive impairment that can be assessed by psychometric, neurophysiologic and radiologic tests. The role of hemosiderosis and iron chelation therapy on cognitive functioning still need more research. β-TM: beta thalassemia major; DFO: Dysferal; DFP: Deferiprone; DFX: Deferasirox; WISC: Wechsler Intelligence Scale for Children; VIQ: verbal IQ; PIQ: performance IQ; TIQ: total IQ; BVRT: Benton Visual Retention Test; WCST: Wisconsin Card Sort Test; MRS: Magnetic resonant spectroscopy; NAA/Cr ratio: N-acetylaspartate to creatine ratio.

Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): A rapid test for enteric coating thickness and integrity of controlled release pellet formulations.

PubMed

Alfarsi, Anas; Dillon, Amy; McSweeney, Seán; Krüse, Jacob; Griffin, Brendan; Devine, Ken; Sherry, Patricia; Henken, Stephan; Fitzpatrick, Stephen; Fitzpatrick, Dara

2018-06-10

There are no rapid dissolution based tests for determining coating thickness, integrity and drug concentration in controlled release pellets either during production or post-production. The manufacture of pellets requires several coating steps depending on the formulation. The sub-coating and enteric coating steps typically take up to six hours each followed by additional drying steps. Post production regulatory dissolution testing also takes up to six hours to determine if the batch can be released for commercial sale. The thickness of the enteric coating is a key factor that determines the release rate of the drug in the gastro-intestinal tract. Also, the amount of drug per unit mass decreases with increasing thickness of the enteric coating. In this study, the coating process is tracked from start to finish on an hourly basis by taking samples of pellets during production and testing those using BARDS (Broadband Acoustic Resonance Dissolution Spectroscopy). BARDS offers a rapid approach to characterising enteric coatings with measurements based on reproducible changes in the compressibility of a solvent due to the evolution of air during dissolution. This is monitored acoustically via associated changes in the frequency of induced acoustic resonances. A steady state acoustic lag time is associated with the disintegration of the enteric coatings in basic solution. This lag time is pH dependent and is indicative of the rate at which the coating layer dissolves. BARDS represents a possible future surrogate test for conventional USP dissolution testing as its data correlates directly with the thickness of the enteric coating, its integrity and also with the drug loading as validated by HPLC. Copyright © 2018 Elsevier B.V. All rights reserved.

Progress Report for a New Cryogenic Sapphire Oscillator

NASA Technical Reports Server (NTRS)

Wang, Rabi T.; Dick, G. J.; Tjoelker, R. L.

2006-01-01

We present design progress and subsystem test results for a new short-term frequency standard, the Voltage Controlled Sapphire Oscillator (VCSO). Included are sapphire resonator and coupling design, cryocooler environmental sensitivity tests, Q measurement results, and turnover temperature results. A previous report presented history of the design related to resonator frequency and frequency compensation [1]. Performance goals are a frequency stability of 1x10(exp -14) (1 second less than or equal to (tau) less than or equal to 100 seconds) and two years or more continuous operation. Long-term operation and small size are facilitated by use of a small Stirling cryo-cooler (160W wall power) with an expected 5 year life.

Sound attenuations of axial fan blade tones using flow-driven tunable resonator arrays

NASA Astrophysics Data System (ADS)

Gorny, Lee James

Flow-excited, tunable quarter-wavelength resonators can be integrated into the shrouds of ducted subsonic axial fans. This study explores their effectiveness in reducing propagations of tonal noise by means of acoustic wave cancellation. Resonators are a non-intrusive method of generating a secondary sound field near the plane of a rotor. As they can be strategically tuned to reduce radiated noise at the blade passage frequency (BPF) and its harmonics, resonators can be useful for a variety of applications to quiet existing and future turbomachinery. Experiments have demonstrated that a single quarter wave resonator is effective in reducing unidirectional plane wave propagations for long wavelength ducted applications while an array is effective for shorter wavelength or un-ducted facilities where shrouded fans are used. Testing conducted at Center for Acoustics and Vibrations (CAV) at the Pennsylvania State University the Deutsches Zentrum fur Luft und Raumfahrt (DLR) in Berlin, Germany demonstrated that resonator arrays were effective in attenuating shorter wavelength plane-wave and higher order modal propagations of blade tone noise. A chiller fan enclosure, constructed in the CAV laboratory emulated an industrial chiller in its operation. Using this facility, resonators were observed to attenuate blade tone noise from a non-ideal ducted geometry. The approaches used in this study evolved from Helmholtz resonators to conventional quarter wave tubes, to mouth tunable resonators, and finally to back-wall tunable resonators. These developments in tuning allowed for independent control of a resonator's magnitude and phase of the secondary sound field produced by the resonators. It was demonstrated that the use of two tunable resonator chambers oriented axially on either side of the blade region enables a dipole-like secondary sound field to be passively generated and bi-directional attenuations of plane wave noise to be achieved. Tonal attenuations of 28 dB were attained and BPF tones were reduced to less than 5 dB from the broadband noise floor for each case discussed above. In parallel with experimental work, analytical models were developed to effectively model and predict optimal resonator configurations for a given fan in operation. Interactions between resonators and the driving pressure field from the rotor blades are modeled using transmission line (TL) theory. Blade tone acoustic pressure is obtained using a finite element method (FEM) propagation code. By combining of these two methods, a resonator configuration that achieves optimal attenuation can be numerically obtained. The use of resonators has been shown to significantly attenuate fan noise in the conditions explored in the considered experiments. Numerical modeling has shown consistency in the response of flow driven resonators and their. These results indicate a strong potential for active control of fan noise using resonators and an approach to applying this control is presented.

Sequentially evaporated thin film YBa2Cu3O(7-x) superconducting microwave ring resonator

NASA Technical Reports Server (NTRS)

Rohrer, Norman J.; To, Hing Y.; Valco, George J.; Bhasin, Kul B.; Chorey, Chris; Warner, Joseph D.

1990-01-01

There is great interest in the application of thin film high temperature superconductors in high frequency electronic circuits. A ring resonator provides a good test vehicle for assessing the microwave losses in the superconductor and for comparing films made by different techniques. Ring resonators made of YBa2Cu3O(7-x) have been investigated on LaAlO3 substrates. The superconducting thin films were deposited by sequential electron beam evaporation of Cu, Y, and BaF2 with a post anneal. Patterning of the superconducting film was done using negative photolithography. A ring resonator was also fabricated from a thin gold film as a control. Both resonators had a gold ground plane on the backside of the substrate. The ring resonators' reflection coefficients were measured as a function of frequency from 33 to 37 GHz at temperatures ranging from 20 K to 68 K. The resonator exhibited two resonances which were at 34.5 and 35.7 GHz at 68 K. The resonant frequencies increased with decreasing temperature. The magnitude of the reflection coefficients was in the calculation of the unloaded Q-values. The performance of the evaporated and gold resonator are compared with the performance of a laser ablated YBa2Cu3O(7-x) resonator. The causes of the double resonance are discussed.

Longitudinal Brain Magnetic Resonance Imaging CO2 Stress Testing in Individual Adolescent Sports-Related Concussion Patients: A Pilot Study.

PubMed

Mutch, W Alan C; Ellis, Michael J; Ryner, Lawrence N; Morissette, Marc P; Pries, Philip J; Dufault, Brenden; Essig, Marco; Mikulis, David J; Duffin, James; Fisher, Joseph A

2016-01-01

Advanced neuroimaging studies in concussion have been limited to detecting group differences between concussion patients and healthy controls. In this small pilot study, we used brain magnetic resonance imaging (MRI) CO2 stress testing to longitudinally assess cerebrovascular responsiveness (CVR) in individual sports-related concussion (SRC) patients. Six SRC patients (three males and three females; mean age = 15.7, range = 15-17 years) underwent longitudinal brain MRI CO2 stress testing using blood oxygen level-dependent (BOLD) MRI and model-based prospective end-tidal CO2 targeting under isoxic conditions. First-level and second-level comparisons were undertaken using statistical parametric mapping (SPM) to score the scans and compare them to an atlas of 24 healthy control subjects. All tests were well tolerated and without any serious adverse events. Anatomical MRI was normal in all study participants. The CO2 stimulus was consistent between the SRC patients and control subjects and within SRC patients across the longitudinal study. Individual SRC patients demonstrated both quantitative and qualitative patient-specific alterations in CVR (p < 0.005) that correlated strongly with clinical findings, and that persisted beyond clinical recovery. Standardized brain MRI CO2 stress testing is capable of providing a longitudinal assessment of CVR in individual SRC patients. Consequently, larger prospective studies are needed to examine the utility of brain MRI CO2 stress testing as a clinical tool to help guide the evaluation, classification, and longitudinal management of SRC patients.

Quantum interference control of an isolated resonance lifetime in the weak-field limit.

PubMed

García-Vela, A

2015-11-21

Resonance states play an important role in a large variety of physical and chemical processes. Thus, controlling the resonance behavior, and particularly a key property like the resonance lifetime, opens up the possibility of controlling those resonance mediated processes. While such a resonance control is possible by applying strong-field approaches, the development of flexible weak-field control schemes that do not alter significantly the system dynamics still remains a challenge. In this work, one such control scheme within the weak-field regime is proposed for the first time in order to modify the lifetime of an isolated resonance state. The basis of the scheme suggested is quantum interference between two pathways induced by laser fields, that pump wave packet amplitude to the target resonance under control. The simulations reported here show that the scheme allows for both enhancement and quenching of the resonance survival lifetime, being particularly flexible to achieve large lifetime enhancements. Control effects on the resonance lifetime take place only while the pulse is operating. In addition, the conditions required to generate the two interfering quantum pathways are found to be rather easy to meet for general systems, which makes the experimental implementation straightforward and implies the wide applicability of the control scheme.

Functional Magnetic Resonance Imaging with Concurrent Urodynamic Testing Identifies Brain Structures Involved in Micturition Cycle in Patients with Multiple Sclerosis.

PubMed

Khavari, Rose; Karmonik, Christof; Shy, Michael; Fletcher, Sophie; Boone, Timothy

2017-02-01

Neurogenic lower urinary tract dysfunction, which is common in patients with multiple sclerosis, has a significant impact on quality of life. In this study we sought to determine brain activity processes during the micturition cycle in female patients with multiple sclerosis and neurogenic lower urinary tract dysfunction. We report brain activity on functional magnetic resonance imaging and simultaneous urodynamic testing in 23 ambulatory female patients with multiple sclerosis. Individual functional magnetic resonance imaging activation maps at strong desire to void and at initiation of voiding were calculated and averaged at Montreal Neuroimaging Institute. Areas of significant activation were identified in these average maps. Subgroup analysis was performed in patients with elicitable neurogenic detrusor overactivity or detrusor-sphincter dyssynergia. Group analysis of all patients at strong desire to void yielded areas of activation in regions associated with executive function (frontal gyrus), emotional regulation (cingulate gyrus) and motor control (putamen, cerebellum and precuneus). Comparison of the average change in activation between previously reported healthy controls and patients with multiple sclerosis showed predominantly stronger, more focal activation in the former and lower, more diffused activation in the latter. Patients with multiple sclerosis who had demonstrable neurogenic detrusor overactivity and detrusor-sphincter dyssynergia showed a trend toward distinct brain activation at full urge and at initiation of voiding respectively. We successfully studied brain activation during the entire micturition cycle in female patients with neurogenic lower urinary tract dysfunction and multiple sclerosis using a concurrent functional magnetic resonance imaging/urodynamic testing platform. Understanding the central neural processes involved in specific parts of micturition in patients with neurogenic lower urinary tract dysfunction may identify areas of interest for future intervention. Copyright © 2017 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Design and Theoretical Analysis of a Resonant Sensor for Liquid Density Measurement

PubMed Central

Zheng, Dezhi; Shi, Jiying; Fan, Shangchun

2012-01-01

In order to increase the accuracy of on-line liquid density measurements, a sensor equipped with a tuning fork as the resonant sensitive component is designed in this paper. It is a quasi-digital sensor with simple structure and high precision. The sensor is based on resonance theory and composed of a sensitive unit and a closed-loop control unit, where the sensitive unit consists of the actuator, the resonant tuning fork and the detector and the closed-loop control unit comprises precondition circuit, digital signal processing and control unit, analog-to-digital converter and digital-to-analog converter. An approximate parameters model of the tuning fork is established and the impact of liquid density, position of the tuning fork, temperature and structural parameters on the natural frequency of the tuning fork are also analyzed. On this basis, a tuning fork liquid density measurement sensor is developed. In addition, experimental testing on the sensor has been carried out on standard calibration facilities under constant 20 °C, and the sensor coefficients are calibrated. The experimental results show that the repeatability error is about 0.03% and the accuracy is about 0.4 kg/m3. The results also confirm that the method to increase the accuracy of liquid density measurement is feasible. PMID:22969378

Design and theoretical analysis of a resonant sensor for liquid density measurement.

PubMed

Zheng, Dezhi; Shi, Jiying; Fan, Shangchun

2012-01-01

In order to increase the accuracy of on-line liquid density measurements, a sensor equipped with a tuning fork as the resonant sensitive component is designed in this paper. It is a quasi-digital sensor with simple structure and high precision. The sensor is based on resonance theory and composed of a sensitive unit and a closed-loop control unit, where the sensitive unit consists of the actuator, the resonant tuning fork and the detector and the closed-loop control unit comprises precondition circuit, digital signal processing and control unit, analog-to-digital converter and digital-to-analog converter. An approximate parameters model of the tuning fork is established and the impact of liquid density, position of the tuning fork, temperature and structural parameters on the natural frequency of the tuning fork are also analyzed. On this basis, a tuning fork liquid density measurement sensor is developed. In addition, experimental testing on the sensor has been carried out on standard calibration facilities under constant 20 °C, and the sensor coefficients are calibrated. The experimental results show that the repeatability error is about 0.03% and the accuracy is about 0.4 kg/m(3). The results also confirm that the method to increase the accuracy of liquid density measurement is feasible.

Development of a multikilowatt ion thruster power processor

NASA Technical Reports Server (NTRS)

Schoenfeld, A. D.; Goldin, D. S.; Biess, J. J.

1972-01-01

A feasibility study was made of the application of silicon-controlled, rectifier series, resonant inverter, power conditioning technology to electric propulsion power processing operating from a 200 to 400 Vdc solar array bus. A power system block diagram was generated to meet the electrical requirements of a 20 CM hollow cathode, mercury bombardment, ion engine. The SCR series resonant inverter was developed as a primary means of power switching and conversion, and the analog signal-to-discrete-time-interval converter control system was applied to achieve good regulation. A complete breadboard was designed, fabricated, and tested with a resistive load bank, and critical power processor areas relating to efficiency, weight, and part count were identified.

Electric prototype power processor for a 30cm ion thruster

NASA Technical Reports Server (NTRS)

Biess, J. J.; Inouye, L. Y.; Schoenfeld, A. D.

1977-01-01

An electrical prototype power processor unit was designed, fabricated and tested with a 30 cm mercury ion engine for primary space propulsion. The power processor unit used the thyristor series resonant inverter as the basic power stage for the high power beam and discharge supplies. A transistorized series resonant inverter processed the remaining power for the low power outputs. The power processor included a digital interface unit to process all input commands and internal telemetry signals so that electric propulsion systems could be operated with a central computer system. The electrical prototype unit included design improvement in the power components such as thyristors, transistors, filters and resonant capacitors, and power transformers and inductors in order to reduce component weight, to minimize losses, and to control the component temperature rise. A design analysis for the electrical prototype is also presented on the component weight, losses, part count and reliability estimate. The electrical prototype was tested in a thermal vacuum environment. Integration tests were performed with a 30 cm ion engine and demonstrated operational compatibility. Electromagnetic interference data was also recorded on the design to provide information for spacecraft integration.

Tuned Chamber Core Panel Acoustic Test Results

NASA Technical Reports Server (NTRS)

Schiller, Noah H.; Allen, Albert R.

2016-01-01

This report documents acoustic testing of tuned chamber core panels, which can be used to supplement the low-frequency performance of conventional acoustic treatment. The tuned chamber core concept incorporates low-frequency noise control directly within the primary structure and is applicable to sandwich constructions with a directional core, including corrugated-, truss-, and fluted-core designs. These types of sandwich structures have long, hollow channels (or chambers) in the core. By adding small holes through one of the facesheets, the hollow chambers can be utilized as an array of low-frequency acoustic resonators. These resonators can then be used to attenuate low-frequency noise (below 400 Hz) inside a vehicle compartment without increasing the weight or size of the structure. The results of this test program demonstrate that the tuned chamber core concept is effective when used in isolation or combined with acoustic foam treatments. Specifically, an array of acoustic resonators integrated within the core of the panels was shown to improve both the low-frequency absorption and transmission loss of the structure in targeted one-third octave bands.

Characterization of low loss microstrip resonators as a building block for circuit QED in a 3D waveguide

NASA Astrophysics Data System (ADS)

Zoepfl, D.; Muppalla, P. R.; Schneider, C. M. F.; Kasemann, S.; Partel, S.; Kirchmair, G.

2017-08-01

Here we present the microwave characterization of microstrip resonators, made from aluminum and niobium, inside a 3D microwave waveguide. In the low temperature, low power limit internal quality factors of up to one million were reached. We found a good agreement to models predicting conductive losses and losses to two level systems for increasing temperature. The setup presented here is appealing for testing materials and structures, as it is free of wire bonds and offers a well controlled microwave environment. In combination with transmon qubits, these resonators serve as a building block for a novel circuit QED architecture inside a rectangular waveguide.

[Magnetic resonance compatibility research for coronary mental stents].

PubMed

Wang, Ying; Liu, Li; Wang, Shuo; Shang, Ruyao; Wang, Chunren

2015-01-01

The objective of this article is to research magnetic resonance compatibility for coronary mental stents, and to evaluate the magnetic resonance compatibility based on laboratory testing results. Coronary stents magnetic resonance compatibility test includes magnetically induced displacement force test, magnetically induced torque test, radio frequency induced heating and evaluation of MR image. By magnetic displacement force and torque values, temperature, and image distortion values to determine metal coronary stent demagnetization effect. The methods can be applied to test magnetic resonance compatibility for coronary mental stents and evaluate its demagnetization effect.

Laboratory test and acoustic analysis of cabin treatment for propfan test assessment aircraft

NASA Technical Reports Server (NTRS)

Kuntz, H. L.; Gatineau, R. J.

1991-01-01

An aircraft cabin acoustic enclosure, built in support of the Propfan Test Assessment (PTA) program, is described. Helmholtz resonators were attached to the cabin trim panels to increase the sidewall transmission loss (TL). Resonators (448) were located between the trim panels and fuselage shell. In addition, 152 resonators were placed between the enclosure and aircraft floors. The 600 resonators were each tuned to a 235 Hz resonance frequency. After flight testing on the PTA aircraft, the enclosure was tested in the Kelly Johnson R and D Center Acoustics Lab. Laboratory noise reduction (NR) test results are discussed. The enclosure was placed in a Gulfstream 2 fuselage section. Broadband (138 dB overall SPL) and tonal (149 dB overall SPL) excitations were used in the lab. Tonal excitation simulated the propfan flight test excitation. The fundamental tone was stepped in 2 Hz intervals from 225 through 245 Hz. The resonators increase the NR of the cabin walls around the resonance frequency of the resonator array. The effects of flanking, sidewall absorption, cabin adsorption, resonator loading of trim panels, and panel vibrations are presented. Increases in NR of up to 11 dB were measured.

Amplitude tests of direct channel resonances: The dibaryon

NASA Astrophysics Data System (ADS)

Goldstein, G. R.; Moravosik, M. J.; Arash, F.

1985-02-01

A recently formulated polarization amplitude test for the existence of one-particle-exchange mechanisms is modified to deal with direct-channel resonances. The results are applied to proton-proton elastic scattering at and around 800 MeV to test the suggested existence of a dibaryon resonance. This test is sensitive to somewhat different circumstances and parameters than the methods used in the past to find dibaryon resonances. The evidence, on the basis of the SAID data set, is negative for a resonance in any singlet partial wave, but is tantalizingly subliminal for a 3F3 resonance.

Amplitude tests of direct channel resonances: the dibaryon

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldstein, G.R.; Moravcsik, M.J.; Arash, F.

A recently formulated polarization amplitude test for the existence of one-particle-exchange mechanisms is modified to deal with direct-channel resonances. The results are applied to proton-proton elastic scattering at and around 800 MeV to test the suggested existence of a dibaryon resonance. This test is sensitive to somewhat different circumstances and parameters than the methods used in the past to find dibaryon resonances. The evidence, on the basis of the SAID data set, is negative for a resonance in any singlet partial wave, but is tantalizingly subliminal for a /sup 3/F/sub 3/ resonance. 7 refs., 4 figs.

Adaptive-passive vibration control systems for industrial applications

NASA Astrophysics Data System (ADS)

Mayer, D.; Pfeiffer, T.; Vrbata, J.; Melz, T.

2015-04-01

Tuned vibration absorbers have become common for passive vibration reduction in many industrial applications. Lightly damped absorbers (also called neutralizers) can be used to suppress narrowband disturbances by tuning them to the excitation frequency. If the resonance is adapted in-operation, the performance of those devices can be significantly enhanced, or inertial mass can be decreased. However, the integration of actuators, sensors and control electronics into the system raises new design challenges. In this work, the development of adaptive-passive systems for vibration reduction at an industrial scale is presented. As an example, vibration reduction of a ship engine was studied in a full scale test. Simulations were used to study the feasibility and evaluate the system concept at an early stage. Several ways to adjust the resonance of the neutralizer were evaluated, including piezoelectric actuation and common mechatronic drives. Prototypes were implemented and tested. Since vibration absorbers suffer from high dynamic loads, reliability tests were used to assess the long-term behavior under operational conditions and to improve the components. It was proved that the adaptive systems are capable to withstand the mechanical loads in an industrial application. Also a control strategy had to be implemented in order to track the excitation frequency. The most mature concepts were integrated into the full scale test. An imbalance exciter was used to simulate the engine vibrations at a realistic level experimentally. The neutralizers were tested at varying excitation frequencies to evaluate the tracking capabilities of the control system. It was proved that a significant vibration reduction is possible.

Resonant power processors. II - Methods of control

NASA Technical Reports Server (NTRS)

Oruganti, R.; Lee, F. C.

1984-01-01

The nature of resonant converter control is discussed. Employing the state-portrait, different control methods for series resonant converter are identified and their performance evaluated based on their stability, response to control and load changes and range of operation. A new control method, optimal-trajectory control, is proposed which, by utilizing the state trajectories as control laws, continuously monitors the energy level of the resonant tank. The method is shown to have superior control properties especially under transient operation.

Inflight dynamics testing of the Apollo spacecraft

NASA Technical Reports Server (NTRS)

Peters, W. H.; Marchantel, B.

1972-01-01

Response of the Apollo command module, service and lunar module airframe while in a docked configuration in the flight environment was measured in a frequency band encompassing the first two bending modes. Transfer characteristics from thrust-application point to control-system sensor were examined. The frequency and the stability margins of the first two predominant structural resonances were verified by the test. This report describes the flight test that was performed and the postflight data analysis.

A comparison of theory and flight test of the BO 105/BMR in hover and forward flight

NASA Technical Reports Server (NTRS)

Mirick, Paul H.

1988-01-01

Four cases were selected for comparison with theoretical predictions using stability data obtained during the flight test of the Bearingless Main Rotor (BMR) on a Messerschmidt-Boelkow-Blohm BO 105 helicopter. The four cases selected form the flight test included two ground resonance cases and two air resonance cases. The BMR used four modified BO 105 blades attached to a bearingless hub. The hub consisted of dual fiberglass C-channel beams attached to the hub center at 0.0238R and attached to the blade root at 0.25R with blade pitch control provided by a torque tube. Analyses from Bell Helicopter Textron, Boeing Vertol, and Sikorsky Aircraft were compared with the data and the correlation ranged from very poor-to-poor to poor-to-fair.

Nondestructive evaluation of warm mix asphalt through resonant column testing.

DOT National Transportation Integrated Search

2014-02-01

Non-destructive testing has been used for decades to characterize engineering properties of hot-mix asphalt. Among such tests is the resonant column (RC) test, which is commonly used to characterize soil materials. The resonant column device at Penn ...

Experimental Evaluation of PV Inverter Anti-Islanding with Grid Support Functions in Multi-Inverter Island Scenarios

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoke, Anderson; Nelson, Austin; Miller, Brian

As PV and other DER systems are connected to the grid at increased penetration levels, island detection may become more challenging for two reasons: 1.) In islands containing many DERs, active inverter-based anti-islanding methods may have more difficulty detecting islands because each individual inverter's efforts to detect the island may be interfered with by the other inverters in the island. 2.) The increasing numbers of DERs are leading to new requirements that DERs ride through grid disturbances and even actively try to regulate grid voltage and frequency back towards nominal operating conditions. These new grid support requirements may directly ormore » indirectly interfere with anti-islanding controls. This report describes a series of tests designed to examine the impacts of both grid support functions and multi-inverter islands on anti-islanding effectiveness. Crucially, the multi-inverter anti-islanding tests described in this report examine scenarios with multiple inverters connected to multiple different points on the grid. While this so-called 'solar subdivision' scenario has been examined to some extent through simulation, this is the first known work to test it using hardware inverters. This was accomplished through the use of power hardware-in-the-loop (PHIL) simulation, which allows the hardware inverters to be connected to a real-time transient simulation of an electric power system that can be easily reconfigured to test various distribution circuit scenarios. The anti-islanding test design was a modified version of the unintentional islanding test in IEEE Standard 1547.1, which creates a balanced, resonant island with the intent of creating a highly challenging condition for island detection. Three common, commercially available single-phase PV inverters from three different manufacturers were tested. The first part of this work examined each inverter individually using a series of pure hardware resistive-inductive-capacitive (RLC) resonant load based anti-islanding tests to determine the worst-case configuration of grid support functions for each inverter. A grid support function is a function an inverter performs to help stabilize the grid or drive the grid back towards its nominal operating point. The four grid support functions examined here were voltage ride-through, frequency ride-through, Volt-VAr control, and frequency-Watt control. The worst-case grid support configuration was defined as the configuration that led to the maximum island duration (or run-on time, ROT) out of 50 tests of each inverter. For each of the three inverters, it was observed that maximum ROT increased when voltage and frequency ride-through were activated. No conclusive evidence was found that Volt-VAr control or frequency-Watt control increased maximum ROT. Over all single-inverter test cases, the maximum ROT was 711 ms, well below the two-second limit currently imposed by IEEE Standard 1547-2003. A subsequent series of 244 experiments tested all three inverters simultaneously in the same island. These tests again used a procedure based on the IEEE 1547.1 unintentional islanding test to create a difficult-to-detect island condition. For these tests, which used the two worst-case grid support function configurations from the single-inverter tests, the inverters were connected to a variety of island circuit topologies designed to represent the variety of multiple-inverter islands that may occur on real distribution circuits. The interconnecting circuits and the resonant island load itself were represented in the real-time PHIL model. PHIL techniques similar to those employed here have been previously used and validated for anti-islanding tests, and the PHIL resonant load model used in this test was successfully validated by comparing single-inverter PHIL tests to conventional tests using an RLC load bank.« less

Compact Radiative Control Structures for Millimeter Astronomy

NASA Technical Reports Server (NTRS)

Brown, Ari D.; Chuss, David T.; Chervenak, James A.; Henry, Ross M.; Moseley, s. Harvey; Wollack, Edward J.

2010-01-01

We have designed, fabricated, and tested compact radiative control structures, including antireflection coatings and resonant absorbers, for millimeter through submillimeter wave astronomy. The antireflection coatings consist of micromachined single crystal silicon dielectric sub-wavelength honeycombs. The effective dielectric constant of the structures is set by the honeycomb cell geometry. The resonant absorbers consist of pieces of solid single crystal silicon substrate and thin phosphorus implanted regions whose sheet resistance is tailored to maximize absorption by the structure. We present an implantation model that can be used to predict the ion energy and dose required for obtaining a target implant layer sheet resistance. A neutral density filter, a hybrid of a silicon dielectric honeycomb with an implanted region, has also been fabricated with this basic approach. These radiative control structures are scalable and compatible for use large focal plane detector arrays.

Comparison between Alzheimer's disease and subcortical vascular dementia: attentional cortex study in functional magnetic resonance imaging.

PubMed

Li, C; Zheng, J; Wang, J; Gui, L

2011-01-01

Blood oxygen level dependent functional magnetic resonance imaging (fMRI) and the Stroop test were used to assess attentional cortex activation in patients with Alzheimer's disease, subcortical vascular dementia, and normal control subjects. Patients with Alzheimer's disease and subcortical vascular dementia demonstrated similar locations of cortical activation, including the bilateral middle and inferior frontal gyri, anterior cingulate and inferior parietal lobule in response to Stroop colour word stimuli. This activation was distinctly decreased in patients with dementia compared with normal control subjects. Different regions of the brain were activated in patients with Alzheimer's disease and subcortical vascular dementia compared with normal controls. fMRI is a useful tool for the study of dementia in humans and has some potential diagnostic value. Further studies with larger numbers of participants are required.

Effects of aging and tactile stochastic resonance on postural performance and postural control in a sensory conflict task.

PubMed

Dettmer, Marius; Pourmoghaddam, Amir; Lee, Beom-Chan; Layne, Charles S

2015-01-01

Postural control in certain situations depends on functioning of tactile or proprioceptive receptors and their respective dynamic integration. Loss of sensory functioning can lead to increased risk of falls in challenging postural tasks, especially in older adults. Stochastic resonance, a concept describing better function of systems with addition of optimal levels of noise, has shown to be beneficial for balance performance in certain populations and simple postural tasks. In this study, we tested the effects of aging and a tactile stochastic resonance stimulus (TSRS) on balance of adults in a sensory conflict task. Nineteen older (71-84 years of age) and younger participants (22-29 years of age) stood on a force plate for repeated trials of 20 s duration, while foot sole stimulation was either turned on or off, and the visual surrounding was sway-referenced. Balance performance was evaluated by computing an Equilibrium Score (ES) and anterior-posterior sway path length (APPlength). For postural control evaluation, strategy scores and approximate entropy (ApEn) were computed. Repeated-measures ANOVA, Wilcoxon signed-rank tests, and Mann-Whitney U-tests were conducted for statistical analysis. Our results showed that balance performance differed between older and younger adults as indicated by ES (p = 0.01) and APPlength (0.01), and addition of vibration only improved performance in the older group significantly (p = 0.012). Strategy scores differed between both age groups, whereas vibration only affected the older group (p = 0.025). Our results indicate that aging affects specific postural outcomes and that TSRS is beneficial for older adults in a visual sensory conflict task, but more research is needed to investigate the effectiveness in individuals with more severe balance problems, for example, due to neuropathy.

Commissioning of inline ECE system within waveguide based ECRH transmission systems on ASDEX upgrade

NASA Astrophysics Data System (ADS)

Bongers, W. A.; Kasparek, W.; Doelman, N.; van den Braber, R.; van den Brand, H.; Meo, F.; de Baar, M. R.; Amerongen, F. J.; Donné, A. J. H.; Elzendoorn, B. S. Q.; Erckmann, V.; Goede, A. P. H.; Giannone, L.; Grünwald, G.; Hollman, F.; Kaas, G.; Krijger, B.; Michel, G.; Lubyako, L.; Monaco, F.; Noke, F.; Petelin, M.; Plaum, B.; Purps, F.; ten Pierik, J. G. W.; Schüller, C.; Slob, J. W.; Stober, J. K.; Schütz, H.; Wagner, D.; Westerhof, E.; Ronden, D. M. S.

2012-09-01

A CW capable inline electron cyclotron emission (ECE) separation system for feedback control, featuring oversized corrugated waveguides, is commissioned on ASDEX upgrade (AUG). The system is based on a combination of a polarization independent, non-resonant, Mach-Zehnder diplexer equipped with dielectric plate beam splitters [2, 3] employed as corrugated oversized waveguide filter, and a resonant Fast Directional Switch, FADIS [4, 5, 6, 7] as ECE/ECCD separation system. This paper presents an overview of the system, the low power characterisation tests and first high power commissioning on AUG.

Dual-Actuator Active Vibration-Control System

NASA Technical Reports Server (NTRS)

Kascak, Albert F.; Kiraly, Louis J.; Montague, Gerald T.; Palazzolo, Alan B.; Manchala, Daniel

1994-01-01

Dual-actuator active vibration-control (DAAVC) system is developmental system of type described in "Active Vibration Dampers for Rotating Machinery" (LEW-15427). System features sensors and actuators positioned and oriented at bearings to measure and counteract vibrations of shaft along either of two axes perpendicular to axis of rotation. Effective in damping vibrations of helicopter-engine test stand, making it safer to operate engine at speeds near and above first resonance of engine/test-stand system. Opens new opportunities for engine designers to draw more power from engine, and concept applicable to other rotating machines.

Oral glutamine challenge and magnetic resonance spectroscopy in three patients with congenital portosystemic shunts.

PubMed

Ortiz, María; Córdoba, Juan; Alonso, Juli; Rovira, Alex; Quiroga, Sergi; Jacas, Carlos; Esteban, Rafael; Guardia, Jaume

2004-03-01

Congenital portosystemic shunts are rare abnormalities of liver vasculature that can cause neurological symptoms, probably secondarily to the effects of the metabolism of ammonia in the brain. Our aim was to investigate the relationship between capillary blood ammonia after oral glutamine challenge and magnetic resonance spectroscopy in three patients with congenital portosystemic shunts. Neuropsychological tests, oral glutamine challenge and magnetic resonance spectroscopy were performed at baseline and after 6 months of follow-up in three patients with congenital portosystemic shunts. The results were compared to those obtained in a group of six cirrhotic patients with prior episodes of hepatic encephalopathy and healthy controls. Patients with congenital portosystemic shunts exhibited abnormalities of neuropsychological tests, magnetic resonance spectroscopy and a response to the oral glutamine challenge similar to those observed in patients with cirrhosis. The intensity of the rise of brain glutamine was correlated to the area under the curve of ammonia after the oral glutamine challenge (R=0.72). Neurological manifestations of patients with congenital portosystemic shunts are mediated through similar mechanisms that are involved in the pathogenesis of hepatic encephalopathy. The area under the curve appears to be the better parameter that defines the response to the oral glutamine challenge.

Excitation power quantities in phase resonance testing of nonlinear systems with phase-locked-loop excitation

NASA Astrophysics Data System (ADS)

Peter, Simon; Leine, Remco I.

2017-11-01

Phase resonance testing is one method for the experimental extraction of nonlinear normal modes. This paper proposes a novel method for nonlinear phase resonance testing. Firstly, the issue of appropriate excitation is approached on the basis of excitation power considerations. Therefore, power quantities known from nonlinear systems theory in electrical engineering are transferred to nonlinear structural dynamics applications. A new power-based nonlinear mode indicator function is derived, which is generally applicable, reliable and easy to implement in experiments. Secondly, the tuning of the excitation phase is automated by the use of a Phase-Locked-Loop controller. This method provides a very user-friendly and fast way for obtaining the backbone curve. Furthermore, the method allows to exploit specific advantages of phase control such as the robustness for lightly damped systems and the stabilization of unstable branches of the frequency response. The reduced tuning time for the excitation makes the commonly used free-decay measurements for the extraction of backbone curves unnecessary. Instead, steady-state measurements for every point of the curve are obtained. In conjunction with the new mode indicator function, the correlation of every measured point with the associated nonlinear normal mode of the underlying conservative system can be evaluated. Moreover, it is shown that the analysis of the excitation power helps to locate sources of inaccuracies in the force appropriation process. The method is illustrated by a numerical example and its functionality in experiments is demonstrated on a benchmark beam structure.

System and method for regulating resonant inverters

DOEpatents

Stevanovic, Ljubisa Dragoljub [Clifton Park, NY; Zane, Regan Andrew [Superior, CO

2007-08-28

A technique is provided for direct digital phase control of resonant inverters based on sensing of one or more parameters of the resonant inverter. The resonant inverter control system includes a switching circuit for applying power signals to the resonant inverter and a sensor for sensing one or more parameters of the resonant inverter. The one or more parameters are representative of a phase angle. The resonant inverter control system also includes a comparator for comparing the one or more parameters to a reference value and a digital controller for determining timing of the one or more parameters and for regulating operation of the switching circuit based upon the timing of the one or more parameters.

Application of extremum seeking for time-varying systems to resonance control of RF cavities

DOE PAGES

Scheinker, Alexander

2016-09-13

A recently developed form of extremum seeking for time-varying systems is implemented in hardware for the resonance control of radio-frequency cavities without phase measurements. Normal conducting RF cavity resonance control is performed via a slug tuner, while superconducting TESLA-type cavity resonance control is performed via piezo actuators. The controller maintains resonance by minimizing reflected power by utilizing model-independent adaptive feedback. Unlike standard phase-measurement-based resonance control, the presented approach is not sensitive to arbitrary phase shifts of the RF signals due to temperature-dependent cable length or phasemeasurement hardware changes. The phase independence of this method removes common slowly varying drifts andmore » required periodic recalibration of phase-based methods. A general overview of the adaptive controller is presented along with the proof of principle experimental results at room temperature. Lastly, this method allows us to both maintain a cavity at a desired resonance frequency and also to dynamically modify its resonance frequency to track the unknown time-varying frequency of an RF source, thereby maintaining maximal cavity field strength, based only on power-level measurements.« less

Electromechanical actuation for thrust vector control applications

NASA Technical Reports Server (NTRS)

Roth, Mary Ellen

1990-01-01

The advanced launch system (ALS), is a launch vehicle that is designed to be cost-effective, highly reliable, and operationally efficient with a goal of reducing the cost per pound to orbit. An electromechanical actuation (EMA) system is being developed as an attractive alternative to the hydraulic systems. The controller will integrate 20 kHz resonant link power management and distribution (PMAD) technology and pulse population modulation (PPM) techniques to implement field-oriented vector control (FOVC) of a new advanced induction motor. The driver and the FOVC will be microprocessor controlled. For increased system reliability, a built-in test (BITE) capability will be included. This involves introducing testability into the design of a system such that testing is calibrated and exercised during the design, manufacturing, maintenance, and prelaunch activities. An actuator will be integrated with the motor controller for performance testing of the EMA thrust vector control (TVC) system. The EMA system and work proposed for the future are discussed.

A study of DC-DC converters with MCT's for arcjet power supplies

NASA Technical Reports Server (NTRS)

Stuart, Thomas A.

1994-01-01

Many arcjet DC power supplies use PWM full bridge converters with large arrays of parallel FET's. This report investigates an alternative supply using a variable frequency series resonant converter with small arrays of parallel MCT's (metal oxide semiconductor controlled thyristors). The reasons for this approach are to: increase reliability by reducing the number of switching devices; and decrease the surface mounting area of the switching arrays. The variable frequency series resonant approach is used because the relatively slow switching speed of the MCT precludes the use of PWM. The 10 kW converter operated satisfactorily with an efficiency of over 91 percent. Test results indicate this efficiency could be increased further by additional optimization of the series resonant inductor.

Analysis of an electrohydraulic aircraft control surface servo and comparison with test results

NASA Technical Reports Server (NTRS)

Edwards, J. W.

1972-01-01

An analysis of an electrohydraulic aircraft control-surface system is made in which the system is modeled as a lumped, two-mass, spring-coupled system controlled by a servo valve. Both linear and nonlinear models are developed, and the effects of hinge-moment loading are included. Transfer functions of the system and approximate literal factors of the transfer functions for several cases are presented. The damping action of dynamic pressure feedback is analyzed. Comparisons of the model responses with results from tests made on a highly resonant rudder control-surface servo indicate the adequacy of the model. The effects of variations in hinge-moment loading are illustrated.

Phonon-tunnelling dissipation in mechanical resonators

PubMed Central

Cole, Garrett D.; Wilson-Rae, Ignacio; Werbach, Katharina; Vanner, Michael R.; Aspelmeyer, Markus

2011-01-01

Microscale and nanoscale mechanical resonators have recently emerged as ubiquitous devices for use in advanced technological applications, for example, in mobile communications and inertial sensors, and as novel tools for fundamental scientific endeavours. Their performance is in many cases limited by the deleterious effects of mechanical damping. In this study, we report a significant advancement towards understanding and controlling support-induced losses in generic mechanical resonators. We begin by introducing an efficient numerical solver, based on the 'phonon-tunnelling' approach, capable of predicting the design-limited damping of high-quality mechanical resonators. Further, through careful device engineering, we isolate support-induced losses and perform a rigorous experimental test of the strong geometric dependence of this loss mechanism. Our results are in excellent agreement with the theory, demonstrating the predictive power of our approach. In combination with recent progress on complementary dissipation mechanisms, our phonon-tunnelling solver represents a major step towards accurate prediction of the mechanical quality factor. PMID:21407197

Viscoelastic coupling of nanoelectromechanical resonators.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simonson, Robert Joseph; Staton, Alan W.

2009-09-01

This report summarizes work to date on a new collaboration between Sandia National Laboratories and the California Institute of Technology (Caltech) to utilize nanoelectromechanical resonators designed at Caltech as platforms to measure the mechanical properties of polymeric materials at length scales on the order of 10-50 nm. Caltech has succeeded in reproducibly building cantilever resonators having major dimensions on the order of 2-5 microns. These devices are fabricated in pairs, with free ends separated by reproducible gaps having dimensions on the order of 10-50 nm. By controlled placement of materials that bridge the very small gap between resonators, the mechanicalmore » devices become coupled through the test material, and the transmission of energy between the devices can be monitored. This should allow for measurements of viscoelastic properties of polymeric materials at high frequency over short distances. Our work to date has been directed toward establishing this measurement capability at Sandia.« less

Sonic resonator control and method for determining component concentration in multiple component molten liquids

DOEpatents

Shen, Sin-Yan

1984-01-01

This invention teaches a control to be used in smelting aluminum by the electrolysis breakdown of alumina (A1.sub.2 O.sub.3) in a molten electrolyte heated to approximately 950.degree.-1000.degree. C. The invention provides a sonic resonator and control that can accurately detect the resonant frequency of the resonator in the molten electrolyte. The resonator preferably is made with tubular side wall 1/4 of the sonic wavelength, or is a quarter wave resonator. A wave generator inputs a signal having a range of frequencies that includes the resonant frequency, so that a peak resonant output at the resonant frequency can be detected on an oscilloscope or like detector. This instantaneous resonant frequency is then checked against an accurate data base correlating the resonant frequencies of the resonator in the electrolyte at specific alumina concentrations normally experienced throughout the electrolysis cycle. The electrolysis cycle can thus be controlled and recharged at any predetermined low alumina concentration greater than where the anode effect phase of the cycle normally might begin.

Control of Fan Blade Vibrations Using Piezoelectrics and Bi-Directional Telemetry

NASA Technical Reports Server (NTRS)

Provenza, Andrew J.; Morrison, Carlos R.

2011-01-01

A novel wireless device which transfers supply power through induction to rotating operational amplifiers and transmits low voltage AC signals to and from a rotating body by way of radio telemetry has been successfully demonstrated in the NASA Glenn Research Center (GRC) Dynamic Spin Test Facility. In the demonstration described herein, a rotating operational amplifier provides controllable AC power to a piezoelectric patch epoxied to the surface of a rotating Ti plate. The amplitude and phase of the sinusoidal voltage command signal, transmitted wirelessly to the amplifier, was tuned to completely suppress the 3rd bending resonant vibration of the plate. The plate's 3rd bending resonance was excited using rotating magnetic bearing excitation while it spun at slow speed in a vacuum chamber. A second patch on the opposite side of the plate was used as a sensor. This paper discusses the characteristics of this novel device, the details of a spin test, results from a preliminary demonstration, and future plans.

A One-Axis-Controlled Magnetic Bearing and Its Performance

NASA Astrophysics Data System (ADS)

Li, Lichuan; Shinshi, Tadahiko; Kuroki, Jiro; Shimokohbe, Akira

Magnetic bearings (MBs) are complex machines in which sensors and controllers must be used to stabilize the rotor. A standard MB requires active control of five motion axes, imposing significant complexity and high cost. In this paper we report a very simple MB and its experimental testing. In this MB, the rotor is stabilized by active control of only one motion axis. The other four motion axes are passively stabilized by permanent magnets and appropriate magnetic circuit design. In rotor radial translational motion, which is passively stabilized, a resonant frequency of 205Hz is achieved for a rotor mass of 11.5×10-3kg. This MB features virtually zero control current and zero rotor iron loss (hysteresis and eddy current losses). Although the rotational speed and accuracy are limited by the resonance of passively stabilized axes, the MB is still suitable for applications where cost is critical but performance is not, such as cooling fans and auxiliary support for aerodynamic bearings.

Analgesic effect of the electromagnetic resonant frequencies derived from the NMR spectrum of morphine.

PubMed

Verginadis, Ioannis I; Simos, Yannis V; Velalopoulou, Anastasia P; Vadalouca, Athina N; Kalfakakou, Vicky P; Karkabounas, Spyridon Ch; Evangelou, Angelos M

2012-12-01

Exposure to various types of electromagnetic fields (EMFs) affects pain specificity (nociception) and pain inhibition (analgesia). Previous study of ours has shown that exposure to the resonant spectra derived from biologically active substances' NMR may induce to live targets the same effects as the substances themselves. The purpose of this study is to investigate the potential analgesic effect of the resonant EMFs derived from the NMR spectrum of morphine. Twenty five Wistar rats were divided into five groups: control group; intraperitoneal administration of morphine 10 mg/kg body wt; exposure of rats to resonant EMFs of morphine; exposure of rats to randomly selected non resonant EMFs; and intraperitoneal administration of naloxone and simultaneous exposure of rats to the resonant EMFs of morphine. Tail Flick and Hot Plate tests were performed for estimation of the latency time. Results showed that rats exposed to NMR spectrum of morphine induced a significant increase in latency time at time points (p < 0.05), while exposure to the non resonant random EMFs exerted no effects. Additionally, naloxone administration inhibited the analgesic effects of the NMR spectrum of morphine. Our results indicate that exposure of rats to the resonant EMFs derived from the NMR spectrum of morphine may exert on animals similar analgesic effects to morphine itself.

Propellant injection strategy for suppressing acoustic combustion instability

NASA Astrophysics Data System (ADS)

Diao, Qina

Shear-coaxial injector elements are often used in liquid-propellant-rocket thrust chambers, where combustion instabilities remain a significant problem. A conventional solution to the combustion instability problem relies on passive control techniques that use empirically-developed hardware such as acoustic baffles and tuned cavities. In addition to adding weight and decreasing engine performance, these devices are designed using trial-and-error methods, which do not provide the capability to predict the overall system stability characteristics in advance. In this thesis, two novel control strategies that are based on propellant fluid dynamics were investigated for mitigating acoustic instability involving shear-coaxial injector elements. The new control strategies would use a set of controlled injectors allowing local adjustment of propellant flow patterns for each operating condition, particularly when instability could become a problem. One strategy relies on reducing the oxidizer-fuel density gradient by blending heavier methane with the main fuel, hydrogen. Another strategy utilizes modifying the equivalence ratio to affect the acoustic impedance through mixing and reaction rate changes. The potential effectiveness of these strategies was assessed by conducting unit-physics experiments. Two different model combustors, one simulating a single-element injector test and the other a double-element injector test, were designed and tested for flame-acoustic interaction. For these experiments, the Reynolds number of the central oxygen jet was kept between 4700 and 5500 making the injector flames sufficiently turbulent. A compression driver, mounted on one side of the combustor wall, provided controlled acoustic excitation to the injector flames, simulating the initial phase of flame-acoustic interaction. Acoustic excitation was applied either as band-limited white noise forcing between 100 Hz and 5000 Hz or as single-frequency, fixed-amplitude forcing at 1150 Hz which represented a frequency least amplified by any resonance. Effects of each control strategy on flame-acoustic interaction were assessed in terms of modifying the acoustic resonance characteristics subject to white-noise excitation and changes in flame brush thickness under single-frequency excitation. In the methane blending experiments, the methane mole fraction was varied between 0% and 63%. Under white noise excitation, up to 16% shift in a resonant frequency was observed but the acoustic pressure spectra remained qualitatively similar. For the fixed frequency forcing, the spatial extent of flame-acoustic interaction was substantially reduced. In the other experiments, the equivalence ratio of the control injector was varied between zero and infinity, causing up to 40% shift in a resonant frequency as well as changes in the acoustic pressure spectrum. These results open up the possibility of employing flow-based control to prevent combustion instabilities in liquid-fueled rockets.

Optimal Topology and Experimental Evaluation of Piezoelectric Materials for Actively Shunted General Electric Polymer Matrix Fiber Composite Blades

NASA Technical Reports Server (NTRS)

Choi, Benjamin B.; Duffy, Kirsten; Kauffman, Jeffrey L.; Kray, Nicholas

2012-01-01

NASA Glenn Research Center, in collaboration with GE Aviation, has begun the development of a smart adaptive structure system with piezoelectric (PE) transducers to improve composite fan blade damping at resonances. Traditional resonant damping approaches may not be realistic for rotating frame applications such as engine blades. The limited space in which the blades reside in the engine makes it impossible to accommodate the circuit size required to implement passive resonant damping. Thus, a novel digital shunt scheme has been developed to replace the conventional electric passive shunt circuits. The digital shunt dissipates strain energy through the load resistor on a power amplifier. General Electric (GE) designed and fabricated a variety of polymer matrix fiber composite (PMFC) test specimens. Investigating the optimal topology of PE sensors and actuators for each test specimen has revealed the best PE transducer location for each target mode. Also a variety of flexible patches, which can conform to the blade surface, have been tested to identify the best performing PE patch. The active damping control achieved significant performance at target modes. This work has been highlighted by successful spin testing up to 5000 rpm of subscale GEnx composite blades in Glenn s Dynamic Spin Rig.

US Coast Guard ASIST Probe Evaluation on a H-65 Dolphin

DTIC Science & Technology

2010-05-01

Turbomeca FADEC (Full Authority Digital Engine Controller) was used to adjust the rotor RPM to the desired value. Due to concerns of exciting resonance...inside the engine, the FADEC controller is designed to not allow continuous operation between 300 and 320 RPM so this rotor RPM range was not tested...the FADEC controller. All other personnel were located southwest of the aircraft to capture data and witness the event. US Coast Guard ASIST

Nine Years of Cooperation: The US-German Memorandum of Understanding (MoU) on Helicopter Aeromechanics 2003-2012

DTIC Science & Technology

2013-12-01

Hamers , Mario, Lantzsch, Robin, Wolfram, Jens: First Control System Evalua- tion of the Research Helicopter FHS, 33rd European Rotorcraft Forum, Kazan...62nd Annual Forum of the AHS, Phoenix, AZ, 2006 [65] Brenner, Hanno, Hamers , Mario: Preparatory Activities for CH-53 Flight Tests with a Slung...Wolfram, Jens, Hamers , Mario: Increasing Handling Qualities and Flight Control Performance using an Air Resonance Controller. 64th Annual Forum of

Enhanced control of dorsolateral prefrontal cortex neurophysiology with real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback training and working memory practice.

PubMed

Sherwood, Matthew S; Kane, Jessica H; Weisend, Michael P; Parker, Jason G

2016-01-01

Real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback can be used to train localized, conscious regulation of blood oxygen level-dependent (BOLD) signals. As a therapeutic technique, rt-fMRI neurofeedback reduces the symptoms of a variety of neurologic disorders. To date, few studies have investigated the use of self-regulation training using rt-fMRI neurofeedback to enhance cognitive performance. This work investigates the utility of rt-fMRI neurofeedback as a tool to enhance human cognition by training healthy individuals to consciously control activity in the left dorsolateral prefrontal cortex (DLPFC). A cohort of 18 healthy participants in the experimental group underwent rt-fMRI neurofeedback from the left DLPFC in five training sessions across two weeks while 7 participants in the control group underwent similar training outside the MRI and without rt-fMRI neurofeedback. Working memory (WM) performance was evaluated on two testing days separated by the five rt-fMRI neurofeedback sessions using two computerized tests. We investigated the ability to control the BOLD signal across training sessions and WM performance across the two testing days. The group with rt-fMRI neurofeedback demonstrated a significant increase in the ability to self-regulate the BOLD signal in the left DLPFC across sessions. WM performance showed differential improvement between testing days one and two across the groups with the highest increases observed in the rt-fMRI neurofeedback group. These results provide evidence that individuals can quickly gain the ability to consciously control the left DLPFC, and this training results in improvements of WM performance beyond that of training alone. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

Multiple-channel guided mode resonance Brewster filter with controllable spectral separation.

PubMed

Ma, Jianyong; Cao, Hongchao; Zhou, Changhe

2014-05-01

In this work, a single-layer, multiple-channel guided mode resonance (GMR) Brewster filter with controllable spectral separation is proposed using the plane waveguide method and rigorous coupled-wave analysis. Based on the normalized eigenvalue equation, the controllability of the spectral separation is analyzed when the fill ratio of the grating layer is changed while its effective index is identical to that of the substrate. The location and the separation between resonances can be specifically controlled by modifying the fill ratio of the grating layer. In contrast to the ordinary GMR filter, where the location of the resonances is material dependent, it is demonstrated that the spectral separation for the first and second resonances can be linearly controlled by altering the fill ratio of the grating layer. In addition, the maximal shift of the second resonance is up to 5% of the first resonant wavelength using the single-layer Brewster filter.

Resonant Frequency Control For the PIP-II Injector Test RFQ: Control Framework and Initial Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Edelen, A. L.; Biedron, S. G.; Milton, S. V.

For the PIP-II Injector Test (PI-Test) at Fermilab, a four-vane radio frequency quadrupole (RFQ) is designed to accelerate a 30-keV, 1-mA to 10-mA, H- beam to 2.1 MeV under both pulsed and continuous wave (CW) RF operation. The available headroom of the RF amplifiers limits the maximum allowable detuning to 3 kHz, and the detuning is controlled entirely via thermal regulation. Fine control over the detuning, minimal manual intervention, and fast trip recovery is desired. In addition, having active control over both the walls and vanes provides a wider tuning range. For this, we intend to use model predictive controlmore » (MPC). To facilitate these objectives, we developed a dedicated control framework that handles higher-level system decisions as well as executes control calculations. It is written in Python in a modular fashion for easy adjustments, readability, and portability. Here we describe the framework and present the first control results for the PI-Test RFQ under pulsed and CW operation.« less

Primer Stepper Motor Nomenclature, Definition, Performance and Recommended Test Methods

NASA Technical Reports Server (NTRS)

Starin, Scott; Shea, Cutter

2014-01-01

There has been an unfortunate lack of standardization of the terms and components of stepper motor performance, requirements definition, application of torque margin and implementation of test methods. This paper will address these inconsistencies and discuss in detail the implications of performance parameters, affects of load inertia, control electronics, operational resonances and recommended test methods. Additionally, this paper will recommend parameters for defining and specifying stepper motor actuators. A useful description of terms as well as consolidated equations and recommended requirements is included.

Testing procedures for carbon fiber reinforced plastic components

NASA Technical Reports Server (NTRS)

Gosse, H. J.; Kaitatzidi, M.; Roth, S.

1977-01-01

Tests for studying the basic material are considered and quality control investigations involving preimpregnated materials (prepreg) are discussed. Attention is given to the prepreg area weight, the fiber area weight of prepregs, the resin content, volatile components, the effective thickness, resin flow, the resistance to bending strain, tensile strength, and shear strength. A description of tests conducted during the manufacturing process is also presented, taking into account X-ray methods, approaches of neutron radiography, ultrasonic procedures, resonance methods and impedance studies.

Laboratory Simulation and Measurement of Instrument Drift in Quartz-Resonant Pressure Gauges

NASA Astrophysics Data System (ADS)

Sasagawa, G. S.; Zumberge, M. A.

2017-12-01

Marine geodesy uses ocean bottom pressure sensors to measure vertical deformation of the sea floor, including that due to volcanic inflation and subsidence, episodic tremor and slip, plate subduction, and deformation due to hydrocarbon extraction at offshore reservoirs. Instrumental drift is inherent in existing pressure sensors and introduce uncertainties in data interpretation. Different methods have been developed to control drift, using varying techniques and instrumentation. Laboratory measurements of sensor drift, under controlled conditions that simulate seafloor pressures and temperatures, would allow for evaluating pressure gauge drift and the efficacy of new drift control methods. We have constructed and operated a laboratory system to monitor the drift of 15 quartz resonant pressure gauges over a year. The temperature and pressure are maintained and controlled at approximately 5 °C and 1900 dbar. A deadweight tester was used to provide a reference signal at frequent intervals; the time series of reference pressure signals is a direct measure of each gauge's drift. Several other tests were conducted, including a) evaluation of a custom outgassing sensor used as proxy for instrument drift, b) determination of the oscillator drift in the pressure gauge signal conditioning electronics, and c) a test of ambient air pressure calibration, also known as the A-0-A method. First results will be presented.

Resonant nonlinear ultrasound spectroscopy

DOEpatents

Johnson, Paul A.; TenCate, James A.; Guyer, Robert A.; Van Den Abeele, Koen E. A.

2001-01-01

Components with defects are identified from the response to strains applied at acoustic and ultrasound frequencies. The relative resonance frequency shift .vertline..DELTA..function./.function..sub.0.vertline., is determined as a function of applied strain amplitude for an acceptable component, where .function..sub.0 is the frequency of the resonance peak at the lowest amplitude of applied strain and .DELTA..function. is the frequency shift of the resonance peak of a selected mode to determine a reference relationship. Then, the relative resonance frequency shift .vertline..DELTA..function./.function..sub.0 is determined as a function of applied strain for a component under test, where fo .function..sub.0 the frequency of the resonance peak at the lowest amplitude of applied strain and .DELTA..function. is the frequency shift of the resonance peak to determine a quality test relationship. The reference relationship is compared with the quality test relationship to determine the presence of defects in the component under test.

Quantification of aquifer properties with surface nuclear magnetic resonance in the Platte River valley, central Nebraska, using a novel inversion method

USGS Publications Warehouse

Irons, Trevor P.; Hobza, Christopher M.; Steele, Gregory V.; Abraham, Jared D.; Cannia, James C.; Woodward, Duane D.

2012-01-01

Surface nuclear magnetic resonance, a noninvasive geophysical method, measures a signal directly related to the amount of water in the subsurface. This allows for low-cost quantitative estimates of hydraulic parameters. In practice, however, additional factors influence the signal, complicating interpretation. The U.S. Geological Survey, in cooperation with the Central Platte Natural Resources District, evaluated whether hydraulic parameters derived from surface nuclear magnetic resonance data could provide valuable input into groundwater models used for evaluating water-management practices. Two calibration sites in Dawson County, Nebraska, were chosen based on previous detailed hydrogeologic and geophysical investigations. At both sites, surface nuclear magnetic resonance data were collected, and derived parameters were compared with results from four constant-discharge aquifer tests previously conducted at those same sites. Additionally, borehole electromagnetic-induction flowmeter data were analyzed as a less-expensive surrogate for traditional aquifer tests. Building on recent work, a novel surface nuclear magnetic resonance modeling and inversion method was developed that incorporates electrical conductivity and effects due to magnetic-field inhomogeneities, both of which can have a substantial impact on the data. After comparing surface nuclear magnetic resonance inversions at the two calibration sites, the nuclear magnetic-resonance-derived parameters were compared with previously performed aquifer tests in the Central Platte Natural Resources District. This comparison served as a blind test for the developed method. The nuclear magnetic-resonance-derived aquifer parameters were in agreement with results of aquifer tests where the environmental noise allowed data collection and the aquifer test zones overlapped with the surface nuclear magnetic resonance testing. In some cases, the previously performed aquifer tests were not designed fully to characterize the aquifer, and the surface nuclear magnetic resonance was able to provide missing data. In favorable locations, surface nuclear magnetic resonance is able to provide valuable noninvasive information about aquifer parameters and should be a useful tool for groundwater managers in Nebraska.

Low frequency cabin noise reduction based on the intrinsic structural tuning concept: The theory and the experimental results, phase 2. [jet aircraft noise

NASA Technical Reports Server (NTRS)

Sengupta, G.

1978-01-01

Low frequency cabin noise and sonically induced stresses in an aircraft fuselage may be reduced by intrinsic tuning of the various structural members such as the skin, stringers, and frames and then applying damping treatments on these members. The concept is also useful in identifying the key structural resonance mechanisms controlling the fuselage response to broadband random excitation and in developing suitable damping treatments for reducing the structural response in various frequency ranges. The mathematical proof of the concept and the results of some laboratory and field tests on a group of skin-stringer panels are described. In the so-called stiffness-controlled region, the noise transmission may actually be controlled by stiffener resonances, depending upon the relationship between the natural frequencies of the skin bay and the stiffeners. Therefore, cabin noise in the stiffness-controlled region may be effectively reduced by applying damping treatments on the stiffeners.

2003 NASA Seal/Secondary Air System Workshop. Volume 1

NASA Technical Reports Server (NTRS)

Steinetz, Bruce M. (Editor); Hendricks, Robert C. (Editor)

2004-01-01

The following reports were included in the 2003 NASA Seal/Secondary Air System Workshop:Low Emissions Alternative Power (LEAP); Overview of NASA Glenn Seal Developments; NASA Ultra Efficient Engine Technology Project Overview; Development of Higher Temperature Abradable Seals for Industrial Gas Turbines; High Misalignment Carbon Seals for the Fan Drive Gear System Technologies; Compliant Foil Seal Investigations; Test Rig for Evaluating Active Turbine Blade Tip Clearance Control Concepts; Controls Considerations for Turbine Active Clearance Control; Non-Contacting Finger Seal Developments and Design Considerations; Effect of Flow-Induced Radial Load on Brush Seal/Rotor Contact Mechanics; Seal Developments at Flowserve Corporation; Investigations of High Pressure Acoustic Waves in Resonators With Seal-Like Features; Numerical Investigations of High Pressure Acoustic Waves in Resonators; Feltmetal Seal Material Through-Flow; "Bimodal" Nuclear Thermal Rocket (BNTR) Propulsion for Future Human Mars Exploration Missions; High Temperature Propulsion System Structural Seals for Future Space Launch Vehicles; Advanced Control Surface Seal Development for Future Space Vehicles; High Temperature Metallic Seal Development for Aero Propulsion and Gas Turbine Applications; and BrazeFoil Honeycomb.

Experiments on reduction of propeller induced interior noise by active control of cylinder vibration

NASA Technical Reports Server (NTRS)

Fuller, C. R.; Jones, J. D.

1987-01-01

The feasibility of reducing interior noise caused by advanced turbo propellers by controlling the vibration of aircraft fuselages was investigated by performing experiments in an anechoic chamber with an aircraft model test rig and apparatus. It was found that active vibration control provides reasonable global attenuation of interior noise levels for the cases of resonant (at 576 Hz) and forced (at 708 Hz) system response. The controlling mechanism behind the effect is structural-acoustic coupling between the shell and the contained field, termed interface modal filtering.

Predictability, Force and (Anti-)Resonance in Complex Object Control.

PubMed

Maurice, Pauline; Hogan, Neville; Sternad, Dagmar

2018-04-18

Manipulation of complex objects as in tool use is ubiquitous and has given humans an evolutionary advantage. This study examined the strategies humans choose when manipulating an object with underactuated internal dynamics, such as a cup of coffee. The object's dynamics renders the temporal evolution complex, possibly even chaotic, and difficult to predict. A cart-and-pendulum model, loosely mimicking coffee sloshing in a cup, was implemented in a virtual environment with a haptic interface. Participants rhythmically manipulated the virtual cup containing a rolling ball; they could choose the oscillation frequency, while the amplitude was prescribed. Three hypotheses were tested: 1) humans decrease interaction forces between hand and object; 2) humans increase the predictability of the object dynamics; 3) humans exploit the resonances of the coupled object-hand system. Analysis revealed that humans chose either a high-frequency strategy with anti-phase cup-and-ball movements or a low-frequency strategy with in-phase cup-and-ball movements. Counter Hypothesis 1, they did not decrease interaction force; instead, they increased the predictability of the interaction dynamics, quantified by mutual information, supporting Hypothesis 2. To address Hypothesis 3, frequency analysis of the coupled hand-object system revealed two resonance frequencies separated by an anti-resonance frequency. The low-frequency strategy exploited one resonance, while the high-frequency strategy afforded more choice, consistent with the frequency response of the coupled system; both strategies avoided the anti-resonance. Hence, humans did not prioritize interaction force, but rather strategies that rendered interactions predictable. These findings highlight that physical interactions with complex objects pose control challenges not present in unconstrained movements.

A macroscopic non-destructive testing system based on the cantilever-sample contact resonance

NASA Astrophysics Data System (ADS)

Fu, Ji; Lin, Lizhi; Zhou, Xilong; Li, Yingwei; Li, Faxin

2012-12-01

Detecting the inside or buried defects in materials and structures is always a challenge in the field of nondestructive testing (NDT). In this paper, enlightened by the operation principle of the contact resonance force microscopy or atomic force acoustic microscopy (AFAM), we proposed a macroscopic NDT system based on contact resonance of the cantilever-sample surface to detect the local stiffness variations in materials or structures. We fabricated a piezoelectric unimorph with the dimension typically of 150 mm × 8 mm × 2 mm to act as a macroscopic cantilever, whose flexural mode vibration was driven by a wideband power amplifier together with a signal generator. The vibration signal of the macroscopic cantilever is detected by a high sensitive strain gauge bonded on the cantilever surface which is much more stable than the laser diode sensor in AFAM, thus making it very suitable for outdoor operations. Scanning is realized by a three-dimensional motorized stage with the Z axis for pressing force setting. The whole system is controlled by a LabVIEW-based homemade software. Like the AFAM, this NDT system can also work in two modes, i.e., the single-frequency mode and the resonance-tracking mode. In the latter mode, the contact stiffness at each pixel of the sample can be obtained by using the measured contact resonance frequency and a beam dynamics model. Testing results of this NDT system on a grid structure with an opaque panel show that in both modes the prefabricated defect beneath the panel can be detected and the grid structures can be clearly "seen," which indicates the validity of this NDT system. The sensitivity of this NDT system was also examined.

Transmission Loss and Absorption of Corrugated Core Sandwich Panels With Embedded Resonators

NASA Technical Reports Server (NTRS)

Allen, Albert R.; Schiller, Noah H.; Zalewski, Bart F.; Rosenthal, Bruce N.

2014-01-01

The effect of embedded resonators on the diffuse field sound transmission loss and absorption of composite corrugated core sandwich panels has been evaluated experimentally. Two 1.219 m × 2.438 m panels with embedded resonator arrangements targeting frequencies near 100 Hz were evaluated using non-standard processing of ASTM E90-09 acoustic transmission loss and ASTM C423-09a room absorption test measurements. Each panel is comprised of two composite face sheets sandwiching a corrugated core with a trapezoidal cross section. When inlet openings are introduced in one face sheet, the chambers within the core can be used as embedded acoustic resonators. Changes to the inlet and chamber partition locations allow this type of structure to be tuned for targeted spectrum passive noise control. Because the core chambers are aligned with the plane of the panel, the resonators can be tuned for low frequencies without compromising the sandwich panel construction, which is typically sized to meet static load requirements. Absorption and transmission loss performance improvements attributed to opening the inlets were apparent for some configurations and inconclusive for others.

Magnetic resonance spectroscopy of current hand amputees reveals evidence for neuronal-level changes in former sensorimotor cortex

PubMed Central

Choi, In-Young; Lee, Phil; Peng, Huiling; Kaufman, Christina L.; Frey, Scott H.

2017-01-01

Deafferentation is accompanied by large-scale functional reorganization of maps in the primary sensory and motor areas of the hemisphere contralateral to injury. Animal models of deafferentation suggest a variety of cellular-level changes including depression of neuronal metabolism and even neuronal death. Whether similar neuronal changes contribute to patterns of reorganization within the contralateral sensorimotor cortex of chronic human amputees is uncertain. We used functional MRI-guided proton magnetic resonance spectroscopy to test the hypothesis that unilateral deafferentation is associated with lower levels of N-acetylaspartate (NAA, a putative marker of neuronal integrity) in the sensorimotor hand territory located contralateral to the missing hand in chronic amputees (n = 19) compared with the analogous hand territory of age- and sex-matched healthy controls (n = 28). We also tested whether former amputees [i.e., recipients of replanted (n = 3) or transplanted (n = 2) hands] exhibit NAA levels that are indistinguishable from controls, possible evidence for reversal of the effects of deafferentation. As predicted, relative to controls, current amputees exhibited lower levels of NAA that were negatively and significantly correlated with the time after amputation. Contrary to our prediction, NAA levels in both replanted and transplanted patients fell within the range of the current amputees. We suggest that lower levels of NAA in current amputees reflects altered neuronal integrity consequent to chronic deafferentation. Thus local changes in NAA levels may provide a means of assessing neuroplastic changes in deafferented cortex. Results from former amputees suggest that these changes may not be readily reversible through reafferentation. NEW & NOTEWORTHY This study is the first to use functional magnetic resonance-guided magnetic resonance spectroscopy to examine neurochemical mechanisms underlying functional reorganization in the primary somatosensory and motor cortices consequent to upper extremity amputation and its potential reversal through hand replantation or transplantation. We provide evidence for selective alteration of cortical neuronal integrity associated with amputation-related deafferentation that may not be reversible. PMID:28179478

Observation of Hamiltonian chaos and its control in wave particle interaction

NASA Astrophysics Data System (ADS)

Doveil, F.; Macor, A.; Aïssi, A.

2007-12-01

Wave-particle interactions are central in plasma physics. They can be studied in a traveling wave tube (TWT) to avoid intrinsic plasma noise. This led to detailed experimental analysis of the self-consistent interaction between unstable waves and an either cold or warm beam. More recently a test cold electron beam has been used to observe its non-self-consistent interaction with externally excited wave(s). The velocity distribution function of the electron beam is recorded with a trochoidal energy analyzer at the output of the TWT. An arbitrary waveform generator is used to launch a prescribed spectrum of waves along the slow wave structure (a 4 m long helix) of the TWT. The nonlinear synchronization of particles by a single wave responsible for Landau damping is observed. The resonant velocity domain associated with a single wave is also observed, as well as the transition to large scale chaos when the resonant domains of two waves and their secondary resonances overlap. This transition exhibits a 'devil's staircase' behavior when increasing the excitation amplitude in agreement with numerical simulation. A new strategy for control of chaos by building barriers of transport which prevent electrons from escaping from a given velocity region as well as its robustness are successfully tested. The underlying concepts extend far beyond the field of electron devices and plasma physics.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scheinker, Alexander

A recently developed form of extremum seeking for time-varying systems is implemented in hardware for the resonance control of radio-frequency cavities without phase measurements. Normal conducting RF cavity resonance control is performed via a slug tuner, while superconducting TESLA-type cavity resonance control is performed via piezo actuators. The controller maintains resonance by minimizing reflected power by utilizing model-independent adaptive feedback. Unlike standard phase-measurement-based resonance control, the presented approach is not sensitive to arbitrary phase shifts of the RF signals due to temperature-dependent cable length or phasemeasurement hardware changes. The phase independence of this method removes common slowly varying drifts andmore » required periodic recalibration of phase-based methods. A general overview of the adaptive controller is presented along with the proof of principle experimental results at room temperature. Lastly, this method allows us to both maintain a cavity at a desired resonance frequency and also to dynamically modify its resonance frequency to track the unknown time-varying frequency of an RF source, thereby maintaining maximal cavity field strength, based only on power-level measurements.« less

PITCH-ANGLE SCATTERING: RESONANCE VERSUS NONRESONANCE, A BASIC TEST OF THE QUASILINEAR DIFFUSIVE RESULT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ragot, B. R.

2012-01-01

Due to the very broad range of the scales available for the development of turbulence in space and astrophysical plasmas, the energy at the resonant scales of wave-particle interaction often constitutes only a tiny fraction of the total magnetic turbulent energy. Despite the high efficiency of resonant wave-particle interaction, one may therefore question whether resonant interaction really is the determining interaction process between particles and turbulent fields. By evaluating and comparing resonant and nonresonant effects in the frame of a quasilinear calculation, the dominance of resonance is here put to the test. By doing so, a basic test of themore » classical resonant quasilinear diffusive result for the pitch-angle scattering of charged energetic particles is also performed.« less

High signal intensity on magnetic resonance imaging is a better predictor of neurobehavioral performances than blood manganese in asymptomatic welders.

PubMed

Chang, Yongmin; Kim, Yangho; Woo, Seung-Tae; Song, Hui-Jin; Kim, Suk Hwan; Lee, Hun; Kwon, Young Joo; Ahn, Joon-Ho; Park, Sin-Jae; Chung, In-Sung; Jeong, Kyoung Sook

2009-07-01

The aim of the study was to evaluate subclinical neurological effects in welders, using an extensive list of neurobehavioral batteries and determine if there is a link between pallidal index (PI) and subclinical neurobehavioral effects in the spectrum of manganese (Mn) symptomatology. A total of 43 asymptomatic male welders and 29 age- and sex-matched healthy control individuals completed questionnaires, and underwent blood examinations, brain magnetic resonance imaging (MRI) scans, and a wide range of neurobehavioral examinations. Digit symbol, auditory verbal learning test (delayed recall), complex figure test (copy and immediate recall), digit span, verbal fluency test, Stroop test, grooved pegboard, finger tapping, frequency dispersion and harmonic index of tremor, and maximum frequency of hand coordination showed differences between welders and control individuals. No differences were noted for simple reaction time, postural sway, smell test, and profile of mood states (POMS). Blood Mn levels were shown to be significantly associated with grooved pegboard (dominant hand) and complex figure test (copy) results. PI was significantly associated with digit symbol, digit span backward, Stroop Word and Stroop error index, and grooved pegboard (dominant hand) results. The present findings that there were significant correlations between several neurobehavioral deficits and PI as well as blood Mn suggest that they may be attributed to Mn exposure in welding fumes. The present study also shows that PI is a better predictor of neurobehavioral performance than blood Mn levels in asymptomatic welders.

A Feasibility Study to Determine Whether Clinical Contrast Enhanced Magnetic Resonance Imaging can Detect Increased Bladder Permeability in Patients with Interstitial Cystitis.

PubMed

Towner, Rheal A; Wisniewski, Amy B; Wu, Dee H; Van Gordon, Samuel B; Smith, Nataliya; North, Justin C; McElhaney, Rayburt; Aston, Christopher E; Shobeiri, S Abbas; Kropp, Bradley P; Greenwood-Van Meerveld, Beverley; Hurst, Robert E

2016-03-01

Interstitial cystitis/bladder pain syndrome is a bladder pain disorder associated with voiding symptomatology and other systemic chronic pain disorders. Currently diagnosing interstitial cystitis/bladder pain syndrome is complicated as patients present with a wide range of symptoms, physical examination findings and clinical test responses. One hypothesis is that interstitial cystitis symptoms arise from increased bladder permeability to urine solutes. This study establishes the feasibility of using contrast enhanced magnetic resonance imaging to quantify bladder permeability in patients with interstitial cystitis. Permeability alterations in bladder urothelium were assessed by intravesical administration of the magnetic resonance imaging contrast agent Gd-DTPA (Gd-diethylenetriaminepentaacetic acid) in a small cohort of patients. Magnetic resonance imaging signal intensity in patient and control bladders was compared regionally and for entire bladders. Quantitative assessment of magnetic resonance imaging signal intensity indicated a significant increase in signal intensity in anterior bladder regions compared to posterior regions in patients with interstitial cystitis (p <0.01) and significant increases in signal intensity in anterior bladder regions (p <0.001). Kurtosis (shape of probability distribution) and skewness (measure of probability distribution asymmetry) were associated with contrast enhancement in total bladders in patients with interstitial cystitis vs controls (p <0.05). Regarding symptomatology interstitial cystitis cases differed significantly from controls on the SF-36®, PUF (Pelvic Pain and Urgency/Frequency) and ICPI (Interstitial Cystitis Problem Index) questionnaires with no overlap in the score range in each group. ICSI (Interstitial Cystitis Symptom Index) differed significantly but with a slight overlap in the range of scores. Data suggest that contrast enhanced magnetic resonance imaging provides an objective, quantifiable measurement of bladder permeability that could be used to stratify bladder pain patients and monitor therapy. Copyright © 2016 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Attitude control compensator for flexible spacecraft

NASA Technical Reports Server (NTRS)

Goodzeit, Neil E. (Inventor); Linder, David M. (Inventor)

1991-01-01

An attitude control loop for a spacecraft uses a proportional-integral-derivative (PID) controller for control about an axis. The spacecraft body has at least a primary mechanical resonance. The attitude sensors are collocated, or both on the rigid portion of the spacecraft. The flexure attributable to the resonance may result in instability of the system. A compensator for the control loop has an amplitude response which includes a component which rolls off beginning at frequencies below the resonance, and which also includes a component having a notch at a notch frequency somewhat below the resonant frequency. The phase response of the compensator tends toward zero at low frequencies, and tends toward -180.degree. as frequency increases toward the notch frequency. At frequencies above the notch frequency, the phase decreases from +180.degree., becoming more negative, and tending toward -90.degree. at frequencies far above the resonance frequency. Near the resonance frequency, the compensator phase is near zero.

A numerical study of active structural acoustic control in a stiffened, double wall cylinder

NASA Technical Reports Server (NTRS)

Grosveld, Ferdinand W.; Coats, T. J.; Lester, H. C.; Silcox, R. J.

1994-01-01

It is demonstrated that active structural acoustic control of complex structural/acoustic coupling can be numerically modeled using finite element and boundary element techniques in conjunction with an optimization procedure to calculate control force amplitudes. Appreciable noise reduction is obtained when the structure is excited at a structural resonance of the outer shell or an acoustic resonance of the inner cavity. Adding ring stiffeners as a connection between the inner and outer shells provides an additional structural transmission path to the interior cavity and coupled the modal behavior of the inner and outer shells. For the case of excitation at the structural resonance of the unstiffened outer shell, adding the stiffeners raises the structural resonance frequencies. The effectiveness of the control forces is reduced due to the off resonance structural response. For excitation at an acoustic cavity resonance, the controller effectiveness is enhanced.

Brain metabolite alterations and cognitive dysfunction in early Huntington’s Disease

PubMed Central

Unschuld, Paul G.; Edden, Richard A. E.; Carass, Aaron; Liu, Xinyang; Shanahan, Megan; Wang, Xin; Oishi, Kenichi; Brandt, Jason; Bassett, Susan S.; Redgrave, Graham W.; Margolis, Russell L.; van Zijl, Peter C. M.; Barker, Peter B.; Ross, Christopher A.

2012-01-01

Background Huntington’s Disease (HD) is a neurodegenerative disorder characterized by early cognitive decline, which progresses at later stages to dementia and severe movement disorder. HD is caused by a cytosine-adenine-guanine triplet-repeat expansion mutation in the Huntingtin gene, allowing early diagnosis by genetic testing. This study aims to identify the relationship of N-acetylaspartate and other brain metabolites to cognitive function in HD-mutation carriers by using high field strength magnetic-resonance-spectroscopy at 7-Tesla. Methods Twelve individuals with the HD-mutation in premanifest or early stage of disease versus twelve healthy controls underwent 1H magnetic-resonance-spectroscopy (7.2ml voxel in the posterior cingulate cortex) at 7-Tesla, and also T1-weighted structural magnetic-resonance-imaging. All participants received standardized tests of cognitive functioning including the Montreal Cognitive Assessment and standardized quantified neurological examination within an hour before scanning. Results Individuals with the HD mutation had significantly lower posterior cingulate cortex N-acetylaspartate (−9.6%, p=0.02) and glutamate levels (−10.1%, p=0.02) than controls. By contrast, in this small group, measures of brain morphology including striatal and ventricle volumes did not differ significantly. Linear regression with Montreal Cognitive Assessment scores revealed significant correlations with N-acetylaspartate (r2=0.50, p=0.01) and glutamate (r2=0.64, p=0.002) in HD subjects. Conclusions Our data suggest a relationship between reduced N-acetylaspartate and glutamate levels in the posterior cingulate cortex with cognitive decline in early stages of HD. N-acetylaspartate and glutamate magnetic-resonance-spectroscopy signals of the posterior cingulate cortex region may serve as potential biomarkers of disease progression or treatment outcome in HD and other neurodegenerative disorders with early cognitive dysfunction, when structural brain changes are still minor. PMID:22649062

Neural Response After a Single ECT Session During Retrieval of Emotional Self-Referent Words in Depression: A Randomized, Sham-Controlled fMRI Study.

PubMed

Miskowiak, Kamilla W; Macoveanu, Julian; Jørgensen, Martin B; Støttrup, Mette M; Ott, Caroline V; Jensen, Hans M; Jørgensen, Anders; Harmer, J; Paulson, Olaf B; Kessing, Lars V; Siebner, Hartwig R

2018-03-01

Negative neurocognitive bias is a core feature of depression that is reversed by antidepressant drug treatment. However, it is unclear whether modulation of neurocognitive bias is a common mechanism of distinct biological treatments. This randomized controlled functional magnetic resonance imaging study explored the effects of a single electroconvulsive therapy session on self-referent emotional processing. Twenty-nine patients with treatment-resistant major depressive disorder were randomized to one active or sham electroconvulsive therapy session at the beginning of their electroconvulsive therapy course in a double-blind, between-groups design. The following day, patients were given a self-referential emotional word categorization test and a free recall test. This was followed by an incidental word recognition task during whole-brain functional magnetic resonance imaging at 3T. Mood was assessed at baseline, on the functional magnetic resonance imaging day, and after 6 electroconvulsive therapy sessions. Data were complete and analyzed for 25 patients (electroconvulsive therapy: n = 14, sham: n = 11). The functional magnetic resonance imaging data were analyzed using the FMRIB Software Library randomize algorithm, and the Threshold-Free Cluster Enhancement method was used to identify significant clusters (corrected at P < .05). A single electroconvulsive therapy session had no effect on hippocampal activity during retrieval of emotional words. However, electroconvulsive therapy reduced the retrieval-specific neural response for positive words in the left frontopolar cortex. This effect occurred in the absence of differences between groups in behavioral performance or mood symptoms. The observed effect of electroconvulsive therapy on prefrontal response may reflect early facilitation of memory for positive self-referent information, which could contribute to improvements in depressive symptoms including feelings of self-worth with repeated treatments.

Nonlinear bounce resonances between magnetosonic waves and equatorially mirroring electrons

NASA Astrophysics Data System (ADS)

Chen, Lunjin; Maldonado, Armando; Bortnik, Jacob; Thorne, Richard M.; Li, Jinxing; Dai, Lei; Zhan, Xiaoya

2015-08-01

Equatorially mirroring energetic electrons pose an interesting scientific problem, since they generally cannot resonate with any known plasma waves and hence cannot be scattered down to lower pitch angles. Observationally it is well known that the flux of these equatorial particles does not simply continue to build up indefinitely, and so a mechanism must necessarily exist that transports these particles from an equatorial pitch angle of 90° down to lower values. However, this mechanism has not been uniquely identified yet. Here we investigate the mechanism of bounce resonance with equatorial noise (or fast magnetosonic waves). A test particle simulation is used to examine the effects of monochromatic magnetosonic waves on the equatorially mirroring energetic electrons, with a special interest in characterizing the effectiveness of bounce resonances. Our analysis shows that bounce resonances can occur at the first three harmonics of the bounce frequency (nωb, n = 1, 2, and 3) and can effectively reduce the equatorial pitch angle to values where resonant scattering by whistler mode waves becomes possible. We demonstrate that the nature of bounce resonance is nonlinear, and we propose a nonlinear oscillation model for characterizing bounce resonances using two key parameters, effective wave amplitude à and normalized wave number k~z. The threshold for higher harmonic resonance is more strict, favoring higher à and k~z, and the change in equatorial pitch angle is strongly controlled by k~z. We also investigate the dependence of bounce resonance effects on various physical parameters, including wave amplitude, frequency, wave normal angle and initial phase, plasma density, and electron energy. It is found that the effect of bounce resonance is sensitive to the wave normal angle. We suggest that the bounce resonant interaction might lead to an observed pitch angle distribution with a minimum at 90°.

Correlation between quantitative whole-body muscle magnetic resonance imaging and clinical muscle weakness in Pompe disease.

PubMed

Horvath, Jeffrey J; Austin, Stephanie L; Case, Laura E; Greene, Karla B; Jones, Harrison N; Soher, Brian J; Kishnani, Priya S; Bashir, Mustafa R

2015-05-01

Previous examination of whole-body muscle involvement in Pompe disease has been limited to physical examination and/or qualitative magnetic resonance imaging (MRI). In this study we assess the feasibility of quantitative proton-density fat-fraction (PDFF) whole-body MRI in late-onset Pompe disease (LOPD) and compare the results with manual muscle testing. Seven LOPD patients and 11 disease-free controls underwent whole-body PDFF MRI. Quantitative MR muscle group assessments were compared with physical testing of muscle groups. The 95% upper limits of confidence intervals for muscle groups were 4.9-12.6% in controls and 6.8-76.4% in LOPD patients. LOPD patients showed severe and consistent tongue and axial muscle group involvement, with less marked involvement of peripheral musculature. MRI was more sensitive than physical examination for detection of abnormality in multiple muscle groups. This integrated, quantitative approach to muscle assessment provides more detailed data than physical examination and may have clinical utility for monitoring disease progression and treatment response. © 2014 Wiley Periodicals, Inc.

Active control of the lifetime of excited resonance states by means of laser pulses.

PubMed

García-Vela, A

2012-04-07

Quantum control of the lifetime of a system in an excited resonance state is investigated theoretically by creating coherent superpositions of overlapping resonances. This control scheme exploits the quantum interference occurring between the overlapping resonances, which can be controlled by varying the width of the laser pulse that creates the superposition state. The scheme is applied to a realistic model of the Br(2)(B)-Ne predissociation decay dynamics through a three-dimensional wave packet method. It is shown that extensive control of the system lifetime is achievable, both enhancing and damping it remarkably. An experimental realization of the control scheme is suggested.

The Dynamical Classification of Centaurs which Evolve into Comets

NASA Astrophysics Data System (ADS)

Wood, Jeremy R.; Horner, Jonathan; Hinse, Tobias; Marsden, Stephen; Swinburne University of Technology

2016-10-01

Centaurs are small Solar system bodies with semi-major axes between Jupiter and Neptune and perihelia beyond Jupiter. Centaurs can be further subclassified into two dynamical categories - random walk and resonance hopping. Random walk Centaurs have mean square semi-major axes (< a2 >) which vary in time according to a generalized diffusion equation where < a2 > ~t2H. H is the Hurst exponent with 0 < H < 1, and t is time. The behavior of < a2 > for resonance hopping Centaurs is not well described by generalized diffusion.The aim of this study is to determine which dynamical type of Centaur is most likely to evolve into each class of comet. 31,722 fictional massless test particles were integrated for 3 Myr in the 6-body problem (Sun, Jovian planets, test particle). Initially each test particle was a member of one of four groups. The semi-major axes of all test particles in a group were clustered within 0.27 au from a first order, interior Mean Motion resonance of Neptune. The resonances were centered at 18.94 au, 22.95 au, 24.82 au and 28.37 au.If the perihelion of a test particle reached < 4 au then the test particle was considered to be a comet and classified as either a random walk or resonance hopping Centaur. The results showed that over 4,000 test particles evolved into comets within 3 Myr. 59% of these test particles were random walk and 41% were resonance hopping. The behavior of the semi-major axis in time was usually well described by generalized diffusion for random walk Centaurs (ravg = 0.98) and poorly described for resonance hopping Centaurs (ravg = 0.52). The average Hurst exponent was 0.48 for random walk Centaurs and 0.20 for resonance hopping Centaurs. Random walk Centaurs were more likely to evolve into short period comets while resonance hopping Centaurs were more likely to evolve into long period comets. For each initial cluster, resonance hopping Centaurs took longer to evolve into comets than random walk Centaurs. Overall the population of random walk Centaurs averaged 143 kyr to evolve into comets, and the population of resonance hopping Centaurs averaged 164 kyr.

Improving labeling efficiency in automatic quality control of MRSI data.

PubMed

Pedrosa de Barros, Nuno; McKinley, Richard; Wiest, Roland; Slotboom, Johannes

2017-12-01

To improve the efficiency of the labeling task in automatic quality control of MR spectroscopy imaging data. 28'432 short and long echo time (TE) spectra (1.5 tesla; point resolved spectroscopy (PRESS); repetition time (TR)= 1,500 ms) from 18 different brain tumor patients were labeled by two experts as either accept or reject, depending on their quality. For each spectrum, 47 signal features were extracted. The data was then used to run several simulations and test an active learning approach using uncertainty sampling. The performance of the classifiers was evaluated as a function of the number of patients in the training set, number of spectra in the training set, and a parameter α used to control the level of classification uncertainty required for a new spectrum to be selected for labeling. The results showed that the proposed strategy allows reductions of up to 72.97% for short TE and 62.09% for long TE in the amount of data that needs to be labeled, without significant impact in classification accuracy. Further reductions are possible with significant but minimal impact in performance. Active learning using uncertainty sampling is an effective way to increase the labeling efficiency for training automatic quality control classifiers. Magn Reson Med 78:2399-2405, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Investigations of High Pressure Acoustic Waves in Resonators with Seal-like Features

NASA Technical Reports Server (NTRS)

Daniels, Christopher; Steinetz, Bruce; Finkbeiner, Joshua

2003-01-01

A conical resonator (having a dissonant acoustic design) was tested in four configurations: (1) baseline resonator with closed ends and no blockage, (2) closed resonator with internal blockage, (3) ventilated resonator with no blockage, and (4) ventilated resonator with an applied pressure differential. These tests were conducted to investigate the effects of blockage and ventilation holes on dynamic pressurization. Additionally, the investigation was to determine the ability of acoustic pressurization to impede flow through the resonator. In each of the configurations studied, the entire resonator was oscillated at the gas resonant frequency while dynamic pressure, static pressure, and temperature of the fluid were measured. In the final configuration, flow through the resonator was recorded for three oscillation conditions. Ambient condition air was used as the working fluid.

Resonance: The science behind the art of sonic drilling

NASA Astrophysics Data System (ADS)

Lucon, Peter Andrew

The research presented in this dissertation quantifies the system dynamics and the influence of control variables of a sonic drill system. The investigation began with an initial body of work funded by the Department of Energy under a Small Business Innovative Research Phase I Grant, grant number: DE-FG02-06ER84618, to investigate the feasibility of using sonic drills to drill micro well holes to depths of 1500 feet. The Department of Energy funding enabled feasibility testing using a 750 hp sonic drill owned by Jeffery Barrow, owner of Water Development Co. During the initial feasibility testing, data was measured and recorded at the sonic drill head while the sonic drill penetrated to a depth of 120 feet. To demonstrate feasibility, the system had to be well understood to show that testing of a larger sonic drill could simulate the results of drilling a micro well hole of 2.5 inch diameter. A first-order model of the system was developed that produced counter-intuitive findings that enabled the feasibility of using this method to drill deeper and produce micro-well holes to 1500 feet using sonic drills. Although funding was not continued, the project work continued. This continued work expanded on the sonic drill models by understanding the governing differential equation and solving the boundary value problem, finite difference methods, and finite element methods to determine the significance of the control variables that can affect the sonic drill. Using a design of experiment approach and commercially available software, the significance of the variables to the effectiveness of the drill system were determined. From the significant variables, as well as the real world testing, a control system schematic for a sonic drill was derived and is patent pending. The control system includes sensors, actuators, personal logic controllers, as well as a human machine interface. It was determined that the control system should control the resonant mode and the weight on the bit as the primary two control variables. The sonic drill can also be controlled using feedback from sensors mounted on the sonic drill head, which is the driver for the sonic drill located above ground

Optimal control design of turbo spin‐echo sequences with applications to parallel‐transmit systems

PubMed Central

Hoogduin, Hans; Hajnal, Joseph V.; van den Berg, Cornelis A. T.; Luijten, Peter R.; Malik, Shaihan J.

2016-01-01

Purpose The design of turbo spin‐echo sequences is modeled as a dynamic optimization problem which includes the case of inhomogeneous transmit radiofrequency fields. This problem is efficiently solved by optimal control techniques making it possible to design patient‐specific sequences online. Theory and Methods The extended phase graph formalism is employed to model the signal evolution. The design problem is cast as an optimal control problem and an efficient numerical procedure for its solution is given. The numerical and experimental tests address standard multiecho sequences and pTx configurations. Results Standard, analytically derived flip angle trains are recovered by the numerical optimal control approach. New sequences are designed where constraints on radiofrequency total and peak power are included. In the case of parallel transmit application, the method is able to calculate the optimal echo train for two‐dimensional and three‐dimensional turbo spin echo sequences in the order of 10 s with a single central processing unit (CPU) implementation. The image contrast is maintained through the whole field of view despite inhomogeneities of the radiofrequency fields. Conclusion The optimal control design sheds new light on the sequence design process and makes it possible to design sequences in an online, patient‐specific fashion. Magn Reson Med 77:361–373, 2017. © 2016 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine PMID:26800383

Feedback control of thermal lensing in a high optical power cavity.

PubMed

Fan, Y; Zhao, C; Degallaix, J; Ju, L; Blair, D G; Slagmolen, B J J; Hosken, D J; Brooks, A F; Veitch, P J; Munch, J

2008-10-01

This paper reports automatic compensation of strong thermal lensing in a suspended 80 m optical cavity with sapphire test mass mirrors. Variation of the transmitted beam spot size is used to obtain an error signal to control the heating power applied to the cylindrical surface of an intracavity compensation plate. The negative thermal lens created in the compensation plate compensates the positive thermal lens in the sapphire test mass, which was caused by the absorption of the high intracavity optical power. The results show that feedback control is feasible to compensate the strong thermal lensing expected to occur in advanced laser interferometric gravitational wave detectors. Compensation allows the cavity resonance to be maintained at the fundamental mode, but the long thermal time constant for thermal lensing control in fused silica could cause difficulties with the control of parametric instabilities.

Prototype Control System for Compensation of Superconducting Cavities Detuning Using Piezoelectric Actuators

NASA Astrophysics Data System (ADS)

Przygoda, K.; Piotrowski, A.; Jablonski, G.; Makowski, D.; Pozniak, T.; Napieralski, A.

2009-08-01

Pulsed operation of high gradient superconducting radio frequency (SCRF) cavities results in dynamic Lorentz force detuning (LFD) approaching or exceeding the bandwidth of the cavity of order of a few hundreds of Hz. The resulting modulation of the resonance frequency of the cavity is leading to a perturbation of the amplitude and phase of the accelerating field, which can be controlled only at the expense of RF power. Presently, at various labs, a piezoelectric fast tuner based on an active compensation scheme for the resonance frequency control of the cavity is under study. The tests already performed in the Free Electron Laser in Hamburg (FLASH), proved the possibility of Lorentz force detuning compensation by the means of the piezo element excited with the single period of sine wave prior to the RF pulse. The X-Ray Free Electron Laser (X-FEL) accelerator, which is now under development in Deutsche Elektronen-Synchrotron (DESY), will consists of around 800 cavities with a fast tuner fixture including the actuator/sensor configuration. Therefore, it is necessary to design a distributed control system which would be able to supervise around 25 RF stations, each one comprised of 32 cavities. The Advanced Telecomunications Computing Architecture (ATCA) was chosen to design, develop, and build a Low Level Radio Frequency (LLRF) controller for X-FEL. The prototype control system for Lorentz force detuning compensation was designed and developed. The control applications applied in the system were fitted to the main framework of interfaces and communication protocols proposed for the ATCA-based LLRF control system. The paper presents the general view of a designed control system and shows the first experimental results from the tests carried out in FLASH facility. Moreover, the possibilities for integration of the piezo control system to the ATCA standards are discussed.

Alterations in regional homogeneity of resting-state cerebral activity in patients with chronic prostatitis/chronic pelvic pain syndrome.

PubMed

Lin, Yusong; Bai, Yan; Liu, Peng; Yang, Xuejuan; Qin, Wei; Gu, Jianqin; Ding, Degang; Tian, Jie; Wang, Meiyun

2017-01-01

The purpose of this study was to explore the neural mechanism in Chronic prostatitis/Chronic pelvic pain syndrome (CP/CPPS) using resting-state functional magnetic resonance imaging. The functional magnetic resonance imaging was performed on 31 male CP/CPPS-patients and 31 age and education matched male healthy controls on a 3-T magnetic resonance imaging unit. A two-sample t-test was adopted to reveal the regional homogeneity between the patients and healthy controls. The mean regional homogeneity values in the alerted brain regions of patients were correlated with the clinical measurements by using Pearson's correlation analyses. The CP/CPPS-patients had significantly decreased regional homogeneity in the bilateral anterior cingulate cortices, insular cortices and right medial prefrontal cortex, while significantly increased regional homogeneity in the brainstem and right thalamus compared with the healthy controls. In the CP/CPPS-patients, the mean regional homogeneity value in the left anterior cingulate cortex, bilateral insular cortices and brainstem were respectively correlated with the National Institutes of Health Chronic Prostatitis Symptom Index total score and pain subscale. These brain regions are important in the pain modulation process. Therefore, an impaired pain modulatory system, either by decreased descending pain inhibition or enhanced pain facilitation, may explain the pain symptoms in CP/CPPS.

Universal feature in optical control of a p -wave Feshbach resonance

NASA Astrophysics Data System (ADS)

Peng, Peng; Zhang, Ren; Huang, Lianghui; Li, Donghao; Meng, Zengming; Wang, Pengjun; Zhai, Hui; Zhang, Peng; Zhang, Jing

2018-01-01

We report the experimental results on the optical control of a p -wave Feshbach resonance by utilizing a laser-driven bound-to-bound transition to shift the energy of a closed-channel molecule state. The magnetic field location for the p -wave resonance as a function of laser detuning can be captured by a simple formula with essentially one parameter, which describes how sensitively the resonance depends on the laser detuning. The key result of this work is to demonstrate, both experimentally and theoretically, that the ratio between this parameter for the m =0 component of the resonance and that for the m =±1 component, to a large extent, is universal. We also show that this optical control can create intriguing situations where interesting few- and many-body physics can occur, such as a p -wave resonance overlapping with an s -wave resonance or the three components of a p -wave resonance being degenerate.

Experimental study on control performance of tuned liquid column dampers considering different excitation directions

NASA Astrophysics Data System (ADS)

Altunişik, Ahmet Can; Yetişken, Ali; Kahya, Volkan

2018-03-01

This paper gives experimental tests' results for the control performance of Tuned Liquid Column Dampers (TLCDs) installed on a prototype structure exposed to ground motions with different directions. The prototype structure designed in the laboratory consists of top and bottom plates with four columns. Finite element analyses and ambient vibration tests are first performed to extract the natural frequencies and mode shapes of the structure. Then, the damping ratio of the structure as well as the resonant frequency, head-loss coefficient, damping ratio, and water height-frequency diagram of the designed TLCD are obtained experimentally by the shaking table tests. To investigate the effect of TLCDs on the structural response, the prototype structure-TLCD coupled system is considered later, and its natural frequencies and related mode shapes are obtained numerically. The acceleration and displacement time-histories are obtained by the shaking table tests to evaluate its damping ratio. To consider different excitation directions, the measurements are repeated for the directions between 0° and 90° with 15° increment. It can be concluded from the study that TLCD causes to decrease the resonant frequency of the structure with increasing of the total mass. Damping ratio considerably increases with installing TLCD on the structure. This is more pronounced for the angles of 0°, 15°, 30° and 45°.

Whispering gallery mode resonators based on radiation-sensitive materials

NASA Technical Reports Server (NTRS)

Savchenkov, Anatoliy (Inventor); Maleki, Lutfollah (Inventor); Ilchenko, Vladimir (Inventor); Handley, Timothy A. (Inventor)

2005-01-01

Whispering gallery mode (WGM) optical resonators formed of radiation-sensitive materials to allow for permanent tuning of their resonance frequencies in a controlled manner. Two WGM resonators may be cascaded to form a composite filter to produce a second order filter function where at least one WGM resonator is formed a radiation-sensitive material to allow for proper control in the overlap of the two filter functions.

Wind Turbine Controller to Mitigate Structural Loads on a Floating Wind Turbine Platform

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fleming, Paul A.; Peiffer, Antoine; Schlipf, David

This paper summarizes the control design work that was performed to optimize the controller of a wind turbine on the WindFloat structure. The WindFloat is a semi-submersible floating platform designed to be a support structure for a multi-megawatt power-generating wind turbine. A controller developed for a bottom-fixed wind turbine configuration was modified for use when the turbine is mounted on the WindFloat platform. This results in an efficient platform heel resonance mitigation scheme. In addition several control modules, designed with a coupled linear model, were added to the fixed-bottom baseline controller. The approach was tested in a fully coupled nonlinearmore » aero-hydroelastic simulation tool in which wind and wave disturbances were modeled. This testing yielded significant improvements in platform global performance and tower-base-bending loading.« less

Anomalous acoustic dispersion in architected microlattice metamaterials

NASA Astrophysics Data System (ADS)

KröDel, Sebastian; Palermo, Antonio; Daraio, Chiara

The ability to control dispersion in acoustic metamaterials is crucial to realize acoustic filtering and rectification devices as well as perfect imaging using negative refractive index materials. Architected microlattice metamaterials immersed in fluid constitute a versatile platform for achieving such control. We investigate architected microlattice materials able to exploit locally resonant modes of their fundamental building blocks that couple with propagating acoustic waves. Using analytical, numerical and experimental methods we find that such lattice materials show a hybrid dispersion behavior governed by Biot's theory for long wavelengths and multiple scattering theory when wave frequency is close to the resonances of the building block. We identify the relevant geometric parameters to alter and control the group and phase velocities in this class of acoustic metamaterials. Furthermore, we fabricate small-scale acoustic metamaterial samples using high precision SLA additive manufacturing and test the resulting materials experimentally using a customized ultrasonic setup. This work paves the way for new acoustic devices based on microlattice metamaterials.

An in-plane nano-mechanics approach to achieve reversible resonance control of photonic crystal nanocavities.

PubMed

Chew, Xiongyeu; Zhou, Guangya; Yu, Hongbin; Chau, Fook Siong; Deng, Jie; Loke, Yee Chong; Tang, Xiaosong

2010-10-11

Control of photonic crystal resonances in conjunction with large spectral shifting is critical in achieving reconfigurable photonic crystal devices. We propose a simple approach to achieve nano-mechanical control of photonic crystal resonances within a compact integrated on-chip approach. Three different tip designs utilizing an in-plane nano-mechanical tuning approach are shown to achieve reversible and low-loss resonance control on a one-dimensional photonic crystal nanocavity. The proposed nano-mechanical approach driven by a sub-micron micro-electromechanical system integrated on low loss suspended feeding nanowire waveguide, achieved relatively large resonance spectral shifts of up to 18 nm at a driving voltage of 25 V. Such designs may potentially be used as tunable optical filters or switches.

High sensitivity real-time NVR monitor

NASA Technical Reports Server (NTRS)

Bowers, William D. (Inventor); Chuan, Raymond L. (Inventor)

1997-01-01

A real time non-volatile residue (NVR) monitor, which utilizes surface acoustic wave (SAW) resonators to detect molecular contamination in a given environment. The SAW resonators operate at a resonant frequency of approximately 200 MHz-2,000 MHz which enables the NVR monitor to detect molecular contamination on the order of 10.sup.-11 g-cm.sup.-2 to 10.sup.-13 g-cm.sup.2. The NVR monitor utilizes active temperature control of (SAW) resonators to achieve a stable resonant frequency. The temperature control system of the NVR monitor is able to directly heat and cool the SAW resonators utilizing a thermoelectric element to maintain the resonators at a present temperature independent of the environmental conditions. In order to enable the direct heating and cooling of the SAW resonators, the SAW resonators are operatively mounted to a heat sink. In one embodiment, the heat sink is located in between the SAW resonators and an electronic circuit board which contains at least a portion of the SAW control electronics. The electrical leads of the SAW resonators are connected through the heat sink to the circuit board via an electronic path which prevents inaccurate frequency measurement.

Faithful conversion of propagating quantum information to mechanical motion

NASA Astrophysics Data System (ADS)

Reed, A. P.; Mayer, K. H.; Teufel, J. D.; Burkhart, L. D.; Pfaff, W.; Reagor, M.; Sletten, L.; Ma, X.; Schoelkopf, R. J.; Knill, E.; Lehnert, K. W.

2017-12-01

The motion of micrometre-sized mechanical resonators can now be controlled and measured at the fundamental limits imposed by quantum mechanics. These resonators have been prepared in their motional ground state or in squeezed states, measured with quantum-limited precision, and even entangled with microwave fields. Such advances make it possible to process quantum information using the motion of a macroscopic object. In particular, recent experiments have combined mechanical resonators with superconducting quantum circuits to frequency-convert, store and amplify propagating microwave fields. But these systems have not been used to manipulate states that encode quantum bits (qubits), which are required for quantum communication and modular quantum computation. Here we demonstrate the conversion of propagating qubits encoded as superpositions of zero and one photons to the motion of a micromechanical resonator with a fidelity in excess of the classical bound. This ability is necessary for mechanical resonators to convert quantum information between the microwave and optical domains or to act as storage elements in a modular quantum information processor. Additionally, these results are an important step towards testing speculative notions that quantum theory may not be valid for sufficiently massive systems.

Radiation sensitivity of quartz crystal oscillators experiment for the Long Duration Exposure Facility (LDEF)

NASA Technical Reports Server (NTRS)

Ahearn, J. S.; Venables, J. D.

1992-01-01

Factors determining the radiation sensitivity of quartz crystal oscillators were studied on NASA's LDEF. Quartz materials were examined in the transmission electron microscope (TEM) and classified as to their sensitivity to radiation damage by establishing the rate of damage caused by the electron beam in the microscope. Two types of materials, i.e., swept premium Q quartz and natural quartz were chosen because clear differences were observed in their response to the electron beam in the TEM studies. Quartz resonators were then fabricated from them, tested for frequency stability over a greater than 6 mo. period and flown on the LDEF satellite. After retrieval (more than 7 yrs in space) the stability of the resonators was again determined. All of the space exposed resonators fabricated with swept premium Q material exhibited a frequency shift above that of the control resonators: none of the resonators fabricated from the natural quartz materials exhibited such a shift. The significant differences observed between the two types of materials in both the ground-based TEM studies and the space radiation induced frequency changes suggest that there may be a correlation between the two observations.

Injection-controlled laser resonator

DOEpatents

Chang, J.J.

1995-07-18

A new injection-controlled laser resonator incorporates self-filtering and self-imaging characteristics with an efficient injection scheme. A low-divergence laser signal is injected into the resonator, which enables the injection signal to be converted to the desired resonator modes before the main laser pulse starts. This injection technique and resonator design enable the laser cavity to improve the quality of the injection signal through self-filtering before the main laser pulse starts. The self-imaging property of the present resonator reduces the cavity induced diffraction effects and, in turn, improves the laser beam quality. 5 figs.

Injection-controlled laser resonator

DOEpatents

Chang, Jim J.

1995-07-18

A new injection-controlled laser resonator incorporates self-filtering and self-imaging characteristics with an efficient injection scheme. A low-divergence laser signal is injected into the resonator, which enables the injection signal to be converted to the desired resonator modes before the main laser pulse starts. This injection technique and resonator design enable the laser cavity to improve the quality of the injection signal through self-filtering before the main laser pulse starts. The self-imaging property of the present resonator reduces the cavity induced diffraction effects and, in turn, improves the laser beam quality.

Implementation of optimal trajectory control of series resonant converter

NASA Technical Reports Server (NTRS)

Oruganti, Ramesh; Yang, James J.; Lee, Fred C.

1987-01-01

Due to the presence of a high-frequency LC tank circuit, the dynamics of a resonant converter are unpredictable. There is often a large surge of tank energy during transients. Using state-plane analysis technique, an optimal trajectory control utilizing the desired solution trajectory as the control law was previously proposed for the series resonant converters. The method predicts the fastest response possible with minimum energy surge in the resonant tank. The principle of the control and its experimental implementation are described here. The dynamics of the converter are shown to be close to time-optimal.

Flexible body control of the airborne telescope SOFIA

NASA Astrophysics Data System (ADS)

Kaercher, Hans J.

2002-07-01

Airborne telescopes have, compared with earthbound or space telescopes, by far the most worse environment during operations. They must not only deal with aircraft vibrations, but also with large temperature differences and aero-acoustic loads including standing waves. System simulations are particularly useful for verifying the design performance in this environment. They should include the behavior of the overall opto-mechanical system, the environmental loads and the pointing control system itself. SOFIA - the "Stratospheric Observatory for Infrared Astronomy" - is a 2,7 m infrared telescope in an open cavity of a Boeing 747 aircraft. At present the telescope is under construction in the MAN premises in Augsburg. Simulations during the design phase of the telescope showed, that there are resonance effects in the telescope excited by the cavity acoustics. The excitations disturb the pointing behavior above the allowances. This paper describes, how the overall system was simulated, how the resonance modes will be compensated by "flexible body control", and how the pointing control system will be finally optimized during test flights in an pointing improvement phase.

Process compensated resonance testing modeling for damage evolution and uncertainty quantification

NASA Astrophysics Data System (ADS)

Biedermann, Eric; Heffernan, Julieanne; Mayes, Alexander; Gatewood, Garrett; Jauriqui, Leanne; Goodlet, Brent; Pollock, Tresa; Torbet, Chris; Aldrin, John C.; Mazdiyasni, Siamack

2017-02-01

Process Compensated Resonance Testing (PCRT) is a nondestructive evaluation (NDE) method based on the fundamentals of Resonant Ultrasound Spectroscopy (RUS). PCRT is used for material characterization, defect detection, process control and life monitoring of critical gas turbine engine and aircraft components. Forward modeling and model inversion for PCRT have the potential to greatly increase the method's material characterization capability while reducing its dependence on compiling a large population of physical resonance measurements. This paper presents progress on forward modeling studies for damage mechanisms and defects in common to structural materials for gas turbine engines. Finite element method (FEM) models of single crystal (SX) Ni-based superalloy Mar-M247 dog bones and Ti-6Al-4V cylindrical bars were created, and FEM modal analyses calculated the resonance frequencies for the samples in their baseline condition. Then the frequency effects of superalloy creep (high-temperature plastic deformation) and macroscopic texture (preferred crystallographic orientation of grains detrimental to fatigue properties) were evaluated. A PCRT sorting module for creep damage in Mar-M247 was trained with a virtual database made entirely of modeled design points. The sorting module demonstrated successful discrimination of design points with as little as 1% creep strain in the gauge section from a population of acceptable design points with a range of material and geometric variation. The resonance frequency effects of macro-scale texture in Ti-6Al-4V were quantified with forward models of cylinder samples. FEM-based model inversion was demonstrated for Mar-M247 bulk material properties and variations in crystallographic orientation. PCRT uncertainty quantification (UQ) was performed using Monte Carlo studies for Mar-M247 that quantified the overall uncertainty in resonance frequencies resulting from coupled variation in geometry, material properties, crystallographic orientation and creep damage. A model calibration process was also developed that evaluates inversion fitting to differences from a designated reference sample rather than absolute property values, yielding a reduction in fit error.

Development of an automatic frequency control system for an X-band (=9300 MHz) RF electron linear accelerator

NASA Astrophysics Data System (ADS)

Cha, Sungsu; Kim, Yujong; Lee, Byung Cheol; Park, Hyung Dal; Lee, Seung Hyun; Buaphad, Pikad

2017-05-01

KAERI is developing a 6 MeV X-band radio frequency (RF) electron linear accelerator for medical purposes. The proposed X-band accelerator consists of an e-gun, an accelerating structure, two solenoid magnets, two steering magnets, a magnetron, a modulator, and an automatic frequency control (AFC) system. The accelerating structure of the component consists of oxygen-free high-conductivity copper (OFHC). Therefore, the ambient temperature changes the volume, and the resonance frequency of the accelerating structure also changes. If the RF frequency of a 9300 MHz magnetron and the resonance frequency of the accelerating structure do not match, it can degrade the performance. That is, it will decrease the output power, lower the beam current, decrease the X-ray dose rate, increase the reflection power, and result in unstable operation of the accelerator. Accelerator operation should be possible at any time during all four seasons. To prevent humans from being exposed to radiation when it is operated, the accelerator should also be operable through remote monitoring and remote control. Therefore, the AFC system is designed to meet these requirements; it is configured based on the concept of a phase-locked loop (PLL) model, which includes an RF section, an intermediate frequency (IF) [1-3] section, and a local oscillator (LO) section. Some resonance frequency controllers use a DC motor, chain, and potentiometer to store the position and tune the frequency [4,5]. Our AFC system uses a step motor to tune the RF frequency of the magnetron. The maximum tuning turn number of our magnetron frequency tuning shaft is ten. Since the RF frequency of our magnetron is 9300±25 MHz, it gives 5 MHz (∵±25 MHz/10 turns → 50 MHz/10 turns =5 MHz/turn) frequency tuning per turn. The rotation angle of our step motor is 0.72° per step and the total step number per one rotation is 360°/0.72°=500 steps. Therefore, the tuning range per step is 10 kHz/step (=5 MHz per turn/500 steps per turn). The developed system is a more compact new resonance frequency control system. In addition, a frequency measuring part is included and it can measure the real-time resonance frequency from the magnetron. We have succeeded in the stable provisioning of RF power by recording the results of a 0.01% frequency deviation in the AFC during an RF test. Accordingly, in this paper, the detailed design, fabrication, and a high power test of the AFC system for the X-band linac are presented.

Anisotropic Mechanical Properties of Magnetically Aligned Fibrin Gels Measured by Magnetic Resonance Elastography

PubMed Central

Namani, Ravi; Wood, Matthew D.; Sakiyama-Elbert, Shelly E.; Bayly, Philip V.

2009-01-01

The anisotropic mechanical properties of magnetically aligned fibrin gels were measured by magnetic resonance elastography (MRE) and by a standard mechanical test: unconfined compression. Soft anisotropic biomaterials are notoriously difficult to characterize, especially in vivo. MRE is well-suited for efficient, non-invasive, and nondestructive assessment of shear modulus. Direction-dependent differences in shear modulus were found to be statistically significant for gels polymerized at magnetic fields of 11.7T and 4.7T compared to control gels. Mechanical anisotropy was greater in the gels polymerized at the higher magnetic field. These observations were consistent with results from unconfined compression tests. Analysis of confocal microscopy images of gels showed measurable alignment of fibrils in gels polymerized at 11.7T. This study provides direct, quantitative measurements of the anisotropy in mechanical properties that accompanies fibril alignment in fibrin gels. PMID:19656516

Alternate methods for high level pyrotechnic shock simulation

NASA Astrophysics Data System (ADS)

Gray, Phillip J., Sr.

Two effective methods to recreate a realistic pyrotechnic shock are presented. The first method employs a resonant beam and is used for SRS levels of 12,000 G or more. The test unit is at one end of the beam and a hammer strikes the opposite end causing a shock to be transmitted to the other end of the fixture. The second method is based on a standard shaker system with a resonant beam to amplify the input signal. The engineer defines the duration of the shock signal induced to the vibration amplifier using the GenRad 2514 controller. The shock signal is then input via the shaker to the resonant beam, which amplifies the signal to produce the desired response at the end of the fixture. The shock response spectrum stays within a +/-6 dB tolerance with levels as high as 3000 G peak. These methods are repeatable, reliable, cost-effective, and consistent with a real pyroevent.

Acoustic propagation in rigid ducts with blockage

NASA Technical Reports Server (NTRS)

El-Raheb, M.; Wagner, P.

1982-01-01

Acoustic levitation has been suggested for moving nonmagnetic material in furnaces for heat processing in space experiments. Basically, acoustic standing waves under resonant conditions are excited in the cavity of the furnace while the material blockage is located at a pressure node and thus at a maximum gradient. The position of the blockage is controlled by displacing the node as a result of frequency change. The present investigation is concerned with the effect of blockage on the longitudinal and transverse resonances of a cylindrical cavity, taking into account the results of a one-dimensional and three-dimensional (3-D) analysis. Based on a Green's function surface element method, 3-D analysis is tested experimentally and proved to be accurate over a wide range of geometric parameters and boundary shapes. The shift in resonance depends on the change in pressure gradient and duct shortening caused by the blockage.

Qubit entanglement between ring-resonator photon-pair sources on a silicon chip

PubMed Central

Silverstone, J. W.; Santagati, R.; Bonneau, D.; Strain, M. J.; Sorel, M.; O'Brien, J. L.; Thompson, M. G.

2015-01-01

Entanglement—one of the most delicate phenomena in nature—is an essential resource for quantum information applications. Scalable photonic quantum devices must generate and control qubit entanglement on-chip, where quantum information is naturally encoded in photon path. Here we report a silicon photonic chip that uses resonant-enhanced photon-pair sources, spectral demultiplexers and reconfigurable optics to generate a path-entangled two-qubit state and analyse its entanglement. We show that ring-resonator-based spontaneous four-wave mixing photon-pair sources can be made highly indistinguishable and that their spectral correlations are small. We use on-chip frequency demultiplexers and reconfigurable optics to perform both quantum state tomography and the strict Bell-CHSH test, both of which confirm a high level of on-chip entanglement. This work demonstrates the integration of high-performance components that will be essential for building quantum devices and systems to harness photonic entanglement on the large scale. PMID:26245267

Experimental Evaluation of Tuned Chamber Core Panels for Payload Fairing Noise Control

NASA Technical Reports Server (NTRS)

Schiller, Noah H.; Allen, Albert R.; Herlan, Jonathan W.; Rosenthal, Bruce N.

2015-01-01

Analytical models have been developed to predict the sound absorption and sound transmission loss of tuned chamber core panels. The panels are constructed of two facesheets sandwiching a corrugated core. When ports are introduced through one facesheet, the long chambers within the core can be used as an array of low-frequency acoustic resonators. To evaluate the accuracy of the analytical models, absorption and sound transmission loss tests were performed on flat panels. Measurements show that the acoustic resonators embedded in the panels improve both the absorption and transmission loss of the sandwich structure at frequencies near the natural frequency of the resonators. Analytical predictions for absorption closely match measured data. However, transmission loss predictions miss important features observed in the measurements. This suggests that higher-fidelity analytical or numerical models will be needed to supplement transmission loss predictions in the future.

Duct wall impedance control as an advanced concept for acoustic impression

NASA Technical Reports Server (NTRS)

Dean, P. D.; Tester, B. J.

1975-01-01

Models and tests on an acoustic duct liner system which has the property of controlled-variable acoustic impedance are described. This is achieved by a novel concept which uses the effect of steady air flow through a multi-layer, locally reacting, resonant-cavity absorber. The scope of this work was limited to a 'proof of concept.' The test of the concept was implemented by means of a small-scale, square-section flow duct facility designed specifically for acoustic measurements, with one side of the duct acoustically lined. The test liners were designed with the aid of previously established duct acoustic theory and a semi-empirical impedance model of the liner system. Over the limited range tested, the liner behaved primarily as predicted, exhibiting significant changes in resistance and reactance, thus providing the necessary concept validation.

Force Limited Vibration Test of HESSI Imager

NASA Technical Reports Server (NTRS)

Amato, Deborah; Pankow, David; Thomsen, Knud

2000-01-01

The High Energy Solar Spectroscopic Imager (HESSI) is a solar x-ray and gamma-ray observatory scheduled for launch in November 2000. Vibration testing of the HESSI imager flight unit was performed in August 1999. The HESSI imager consists of a composite metering tube, two aluminum trays mounted to the tube on titanium flexure mounts, and nine modulation grids mounted on each tray. The vibration tests were acceleration controlled and force limited, in order to prevent overtesting. The force limited strategy reduced the shaker force and notched the acceleration at resonances. The test set-up, test levels, and results are presented. The development of the force limits is also discussed. The imager successfully survived the vibration testing.

Evidence for early neurodegeneration in the cervical cord of patients with primary progressive multiple sclerosis

PubMed Central

Schneider, Torben; Solanky, Bhavana S.; Yiannakas, Marios C.; Altmann, Dan R.; Wheeler-Kingshott, Claudia A. M.; Peters, Amy L.; Day, Brian L.; Thompson, Alan J.; Ciccarelli, Olga

2015-01-01

Spinal neurodegeneration is an important determinant of disability progression in patients with primary progressive multiple sclerosis. Advanced imaging techniques, such as single-voxel 1H-magnetic resonance spectroscopy and q-space imaging, have increased pathological specificity for neurodegeneration, but are challenging to implement in the spinal cord and have yet to be applied in early primary progressive multiple sclerosis. By combining these imaging techniques with new clinical measures, which reflect spinal cord pathology more closely than conventional clinical tests, we explored the potential for spinal magnetic resonance spectroscopy and q-space imaging to detect early spinal neurodegeneration that may be responsible for clinical disability. Data from 21 patients with primary progressive multiple sclerosis within 6 years of disease onset, and 24 control subjects were analysed. Patients were clinically assessed on grip strength, vibration perception thresholds and postural stability, in addition to the Expanded Disability Status Scale, Nine Hole Peg Test, Timed 25-Foot Walk Test, Multiple Sclerosis Walking Scale-12, and Modified Ashworth Scale. All subjects underwent magnetic resonance spectroscopy and q-space imaging of the cervical cord and conventional brain and spinal magnetic resonance imaging at 3 T. Multivariate analyses and multiple regression models were used to assess the differences in imaging measures between groups and the relationship between magnetic resonance imaging measures and clinical scores, correcting for age, gender, spinal cord cross-sectional area, brain T2 lesion volume, and brain white matter and grey matter volume fractions. Although patients did not show significant cord atrophy when compared with healthy controls, they had significantly lower total N-acetyl-aspartate (mean 4.01 versus 5.31 mmol/l, P = 0.020) and glutamate-glutamine (mean 4.65 versus 5.93 mmol/l, P = 0.043) than controls. Patients showed an increase in q-space imaging-derived indices of perpendicular diffusivity in both the whole cord and major columns compared with controls (P < 0.05 for all indices). Lower total N-acetyl-aspartate was associated with higher disability, as assessed by the Expanded Disability Status Scale (coefficient = −0.41, 0.01 < P < 0.05), Modified Ashworth Scale (coefficient = −3.78, 0.01 < P < 0.05), vibration perception thresholds (coefficient = −4.37, P = 0.021) and postural sway (P < 0.001). Lower glutamate-glutamine predicted increased postural sway (P = 0.017). Increased perpendicular diffusivity in the whole cord and columns was associated with increased scores on the Modified Ashworth Scale, vibration perception thresholds and postural sway (P < 0.05 in all cases). These imaging findings indicate reduced structural integrity of neurons, demyelination, and abnormalities in the glutamatergic pathways in the cervical cord of early primary progressive multiple sclerosis, in the absence of extensive spinal cord atrophy. The observed relationship between imaging measures and disability suggests that early spinal neurodegeneration may underlie clinical impairment, and should be targeted in future clinical trials with neuroprotective agents to prevent the development of progressive disability. PMID:25863355

The contribution of hospital nursing leadership styles to 30-day patient mortality.

PubMed

Cummings, Greta G; Midodzi, William K; Wong, Carol A; Estabrooks, Carole A

2010-01-01

Nursing work environment characteristics, in particular nurse and physician staffing, have been linked to patient outcomes (adverse events and patient mortality). Researchers have stressed the need for nursing leadership to advance change in healthcare organizations to create safer practice environments for patients. The relationship between styles of nursing leadership in hospitals and patient outcomes has not been well examined. The purpose of this study was to examine the contribution of hospital nursing leadership styles to 30-day mortality after controlling for patient demographics, comorbidities, and hospital factors. Ninety acute care hospitals in Alberta, Canada, were categorized into five styles of nursing leadership: high resonant, moderately resonant, mixed, moderately dissonant, and high dissonant. In the secondary analysis, existing data from three sources (nurses, patients, and institutions) were used to test a hypothesis that the styles of nursing leadership at the hospital level contribute to patient mortality rates. Thirty-day mortality was 7.8% in the study sample of 21,570 medical patients; rates varied across hospital categories: high resonant (5.2%), moderately resonant (7.4%), mixed (8.1%), moderately dissonant (8.8%), and high dissonant (4.3%). After controlling for patient demographics, comorbidities, and institutional and hospital nursing characteristics, nursing leadership styles explained 5.1% of 72.2% of total variance in mortality across hospitals, and high-resonant leadership was related significantly to lower mortality. Hospital nursing leadership styles may contribute to 30-day mortality of patients. This relationship may be moderated by homogeneity of leadership styles, clarity of communication among leaders and healthcare providers, and work environment characteristics.

Powerful timing generator using mono-chip timers: An application to pulsed nuclear magnetic resonance

NASA Astrophysics Data System (ADS)

Saint-Jalmes, Hervé; Barjhoux, Yves

1982-01-01

We present a 10 line-7 MHz timing generator built on a single board around two LSI timer chips interfaced to a 16-bit microcomputer. Once programmed from the host computer, this device is able to generate elaborate logic sequences on its 10 output lines without further interventions from the CPU. Powerful architecture introduces new possibilities over conventional memory-based timing simulators and word generators. Loop control on a given sequence of events, loop nesting, and various logic combinations can easily be implemented through a software interface, using a symbolic command language. Typical applications of such a device range from development, emulation, and test of integrated circuits, circuit boards, and communication systems to pulse-controlled instrumentation (radar, ultrasonic systems). A particular application to a pulsed Nuclear Magnetic Resonance (NMR) spectrometer is presented, along with customization of the device for generating four-channel radio-frequency pulses and the necessary sequence for subsequent data acquisition.

Nonlinear Properties in Langasite Isomorphs for Advanced Frequency Control Devices and Clocks

DTIC Science & Technology

2006-11-01

or LGN), and langatate (La3Ga5.5Ta0.5O14 or LGT), have emerged as new materials to replace quartz in advanced frequency control devices and clocks...application and of angle Ψ. Fig. 1. Langatate boule (photo courtesy of the Univ. Central Florida) and typical resonators for testing. Table 1...langanite and y-cut langatate ,” IEEE Tr. Ultrason. Ferroelec. Freq. Contr., pp. 1678-1682, 2003. Kim, Y., “Amplitude-frequency effect of Y-cut langanite

Effects of specimen resonances on acoustic-ultrasonic testing

NASA Technical Reports Server (NTRS)

Williams, J. H., Jr.; Kahn, E. B.; Lee, S. S.

1983-01-01

The effects of specimen resonances on acoustic ultrasonic (AU) nondestructive testing were investigated. Selected resonant frequencies and the corresponding normal mode nodal patterns of the aluminum block are measured up to 75.64 kHz. Prominent peaks in the pencil lead fracture and sphere impact spectra from the two transducer locations corresponded exactly to resonant frequencies of the block. It is established that the resonant frequencies of the block dominated the spectral content of the output signal. The spectral content of the output signals is further influenced by the transducer location relative to the resonant frequency nodal lines. Implications of the results are discussed in relation to AU parameters and measurements.

Benchmark Testing of a New 56Fe Evaluation for Criticality Safety Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leal, Luiz C; Ivanov, E.

2015-01-01

The SAMMY code was used to evaluate resonance parameters of the 56Fe cross section in the resolved resonance energy range of 0–2 MeV using transmission data, capture, elastic, inelastic, and double differential elastic cross sections. The resonance analysis was performed with the code SAMMY that fits R-matrix resonance parameters using the generalized least-squares technique (Bayes’ theory). The evaluation yielded a set of resonance parameters that reproduced the experimental data very well, along with a resonance parameter covariance matrix for data uncertainty calculations. Benchmark tests were conducted to assess the evaluation performance in benchmark calculations.

Power flow control based solely on slow feedback loop for heart pump applications.

PubMed

Wang, Bob; Hu, Aiguo Patrick; Budgett, David

2012-06-01

This paper proposes a new control method for regulating power flow via transcutaneous energy transfer (TET) for implantable heart pumps. Previous work on power flow controller requires a fast feedback loop that needs additional switching devices and resonant capacitors to be added to the primary converter. The proposed power flow controller eliminates these additional components, and it relies solely on a slow feedback loop to directly drive the primary converter to meet the heart pump power demand and ensure zero voltage switching. A controlled change in switching frequency varies the resonant tank shorting period of a current-fed push-pull resonant converter, thus changing the magnitude of the primary resonant voltage, as well as the tuning between primary and secondary resonant tanks. The proposed controller has been implemented successfully using an analogue circuit and has reached an end-to-end power efficiency of 79.6% at 10 W with a switching frequency regulation range of 149.3 kHz to 182.2 kHz.

Simulation Analysis of Helicopter Ground Resonance Nonlinear Dynamics

NASA Astrophysics Data System (ADS)

Zhu, Yan; Lu, Yu-hui; Ling, Ai-min

2017-07-01

In order to accurately predict the dynamic instability of helicopter ground resonance, a modeling and simulation method of helicopter ground resonance considering nonlinear dynamic characteristics of components (rotor lead-lag damper, landing gear wheel and absorber) is presented. The numerical integral method is used to calculate the transient responses of the body and rotor, simulating some disturbance. To obtain quantitative instabilities, Fast Fourier Transform (FFT) is conducted to estimate the modal frequencies, and the mobile rectangular window method is employed in the predictions of the modal damping in terms of the response time history. Simulation results show that ground resonance simulation test can exactly lead up the blade lead-lag regressing mode frequency, and the modal damping obtained according to attenuation curves are close to the test results. The simulation test results are in accordance with the actual accident situation, and prove the correctness of the simulation method. This analysis method used for ground resonance simulation test can give out the results according with real helicopter engineering tests.

Control of slow-to-fast light and single-to-double optomechanically induced transparency in a compound resonator system: A theoretical approach

NASA Astrophysics Data System (ADS)

Ziauddin; Rahman, Mujeeb ur; Ahmad, Iftikhar; Qamar, Sajid

2017-10-01

The transmission characteristics of probe light field is investigated theoretically in a compound system of two coupled resonators. The proposed system consisted of two high-Q Fabry-Perot resonators in which one of the resonators is optomechanical. Optomechanically induced transparency (OMIT), having relatively large window, is noticed via strong coupling between the two resonators. We investigate tunable switching from single to double OMIT by increasing amplitude of the pump field. We notice that, control of slow and fast light can be obtained via the coupling strength between the two resonators.

Magnetic characteristics of a high-layer-number NiFe/FeMn multilayer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paterson, G. W., E-mail: gary.paterson@glasgow.ac.uk; Gonçalves, F. J. T.; McFadzean, S.

2015-11-28

We report the static and dynamic magnetic characteristics of a high-layer-number NiFe/FeMn multilayer test structure with potential applications in broadband absorber and filter devices. To allow fine control over the absorption linewidths and to understand the mechanisms governing the resonances in a tailored structure similar to that expected to be used in real world applications, the multilayer was intentionally designed to have layer thickness and interface roughness variations. Magnetometry measurements show that the sample has complex hysteresis loops with features consistent with single ferromagnetic film reversals. Characterisation by transmission electron microscopy allows us to correlate the magnetic properties with structuralmore » features, including the film widths and interface roughnesses. Analysis of resonance frequencies from broadband ferromagnetic resonance measurements as a function of field magnitude and orientation provide values of the local exchange bias, rotatable anisotropy, and uniaxial anisotropy fields for specific layers in the stack and explain the observed mode softening. The linewidths of the multilayer are adjustable around the bias field, approaching twice that seen at larger fields, allowing control over the bandwidth of devices formed from the structure.« less

Resonant vibration control of rotating beams

NASA Astrophysics Data System (ADS)

Svendsen, Martin Nymann; Krenk, Steen; Høgsberg, Jan

2011-04-01

Rotating structures, like e.g. wind turbine blades, may be prone to vibrations associated with particular modes of vibration. It is demonstrated, how this type of vibrations can be reduced by using a collocated sensor-actuator system, governed by a resonant controller. The theory is here demonstrated by an active strut, connecting two cross-sections of a rotating beam. The structure is modeled by beam elements in a rotating frame of reference following the beam. The geometric stiffness is derived in a compact form from an initial stress formulation in terms of section forces and moments. The stiffness, and thereby the natural frequencies, of the beam depend on the rotation speed and the controller is tuned to current rotation speed to match the resonance frequency of the selected mode. It is demonstrated that resonant control leads to introduction of the intended level of damping in the selected mode and, with good modal connectivity, only very limited modal spill-over is generated. The controller acts by resonance and therefore has only a moderate energy consumption, and successfully reduces modal vibrations at the resonance frequency.

Optically-controlled extinction ratio and Q-factor tunable silicon microring resonators based on optical forces

NASA Astrophysics Data System (ADS)

Long, Yun; Wang, Jian

2014-06-01

Tunability is a desirable property of microring resonators to facilitate superior performance. Using light to control light, we present an alternative simple approach to tuning the extinction ratio (ER) and Q-factor of silicon microring resonators based on optical forces. We design an opto-mechanical tunable silicon microring resonator consisting of an add-drop microring resonator and a control-light-carrying waveguide (``controlling'' waveguide). One of the two bus waveguides of the microring resonator is a deformable nanostring put in parallel with the ``controlling'' waveguide. The tuning mechanism relies on the optical force induced deflection of suspended nanostring, leading to the change of coupling coefficient of microring and resultant tuning of ER and Q-factor. Two possible geometries, i.e. double-clamped nanostring and cantilever nanostring, are studied in detail for comparison. The obtained results imply a favorable structure with the microring positioned at the end of the cantilever nanostring. It features a wide tuning range of ER from 5.6 to 39.9 dB and Q-factor from 309 to 639 as changing the control power from 0 to 1.4 mW.

Development and validation of a questionnaire evaluating patient anxiety during Magnetic Resonance Imaging: the Magnetic Resonance Imaging-Anxiety Questionnaire (MRI-AQ).

PubMed

Ahlander, Britt-Marie; Årestedt, Kristofer; Engvall, Jan; Maret, Eva; Ericsson, Elisabeth

2016-06-01

To develop and validate a new instrument measuring patient anxiety during Magnetic Resonance Imaging examinations, Magnetic Resonance Imaging- Anxiety Questionnaire. Questionnaires measuring patients' anxiety during Magnetic Resonance Imaging examinations have been the same as used in a wide range of conditions. To learn about patients' experience during examination and to evaluate interventions, a specific questionnaire measuring patient anxiety during Magnetic Resonance Imaging is needed. Psychometric cross-sectional study with test-retest design. A new questionnaire, Magnetic Resonance Imaging-Anxiety Questionnaire, was designed from patient expressions of anxiety in Magnetic Resonance Imaging-scanners. The sample was recruited between October 2012-October 2014. Factor structure was evaluated with exploratory factor analysis and internal consistency with Cronbach's alpha. Criterion-related validity, known-group validity and test-retest was calculated. Patients referred for Magnetic Resonance Imaging of either the spine or the heart, were invited to participate. The development and validation of Magnetic Resonance Imaging-Anxiety Questionnaire resulted in 15 items consisting of two factors. Cronbach's alpha was found to be high. Magnetic Resonance Imaging-Anxiety Questionnaire correlated higher with instruments measuring anxiety than with depression scales. Known-group validity demonstrated a higher level of anxiety for patients undergoing Magnetic Resonance Imaging scan of the heart than for those examining the spine. Test-retest reliability demonstrated acceptable level for the scale. Magnetic Resonance Imaging-Anxiety Questionnaire bridges a gap among existing questionnaires, making it a simple and useful tool for measuring patient anxiety during Magnetic Resonance Imaging examinations. © 2016 The Authors. Journal of Advanced Nursing Published by John Wiley & Sons Ltd.

Elastodynamic metasurface: Depolarization of mechanical waves and time effects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boutin, Claude, E-mail: claude.boutin@entpe.fr; Schwan, Logan; Dietz, Matthew S.

2015-02-14

We report the concept of microstructured surfaces with inner resonance in the field of elastodynamics, so-called elastodynamic metasurfaces. Such metasurfaces allow for wavefield manipulation of mechanical waves by tuning the boundary conditions at specific frequencies. In particular, they can be used to depolarize elastic waves without introducing heterogeneities in the medium itself; the physical means to do so in homogeneous elastic media used to remain, surprisingly, an open question while depolarization is commonplace in electromagnetism. The principle relies on the anisotropic behaviour of a subwavelength array of resonators: Their subwavelength configuration confines the Bragg interferences scattered by resonators into amore » boundary layer. The effective behaviour of the resonating array is expressed with homogenization as an unconventional impedance, the frequency-dependence, and anisotropy of which lead to depolarization and time effects. The concept of the elastodynamic metasurface is tested experimentally and results bear testament to its efficacy and robustness. Elastodynamic metasurfaces are easily realized and analytically predictable, opening new possibilities in tomography techniques, ultrasonics, geophysics, vibration control, materials and structure design.« less

Active control of helicopter air resonance in hover and forward flight

NASA Technical Reports Server (NTRS)

Takahashi, M. D.; Friedman, P. P.

1988-01-01

A coupled rotor/fuselage helicopter analysis is presented. The accuracy of the model is illustrated by comparing it with experimental data. The sensitivity of the open loop damping of the unstable resonance mode to such modeling effects as blade torsional flexibility, unsteady aerodynamics, forward flight, periodic terms, and trim solution is illustrated by numerous examples. Subsequently, the model is used in conjunction with linear optimal control theory to stabilize the air resonance mode. The influence of the modeling effects mentioned before on active resonance control is then investigated.

Electromagnetic compatibility (EMC) standard test chamber upgrade requirements for spacecraft design verification tests

NASA Technical Reports Server (NTRS)

Dyer, Edward F.

1992-01-01

In view of the serious performance deficiencies inherent in conventional modular and welded shielding EMC test enclosures, in which multipath reflections and resonant standing waves can damage flight hardware during RF susceptibility tests, NASA-Goddard has undertaken the modification of a 20 x 24 ft modular-shielded enclosure through installation of steel panels to which ferrite tiles will be mounted with epoxy. The internally reflected RF energy will thereby be absorbed, and exterior power-line noise will be reduced. Isolation of power-line filters and control of 60-Hz ground connections will also be undertaken in the course of upgrading.

Arthroscopic repair of traumatic isolated subscapularis tendon lesions (Lafosse Type III or IV): a prospective magnetic resonance imaging-controlled case series with 1 year of follow-up.

PubMed

Grueninger, Patrick; Nikolic, Nikola; Schneider, Joerg; Lattmann, Thomas; Platz, Andreas; Chmiel, Corinne; Meier, Christoph

2014-06-01

The purpose of this study was to prospectively assess the efficacy of arthroscopic repair of isolated high-grade subscapularis (SSC) tendon lesions by means of clinical follow-up combined with magnetic resonance imaging investigations. Between January 2008 and September 2010, 11 patients (9 men and 2 women; mean age, 45 ± 10 years) with Lafosse type III or IV traumatic isolated SSC tendon lesions underwent arthroscopic repair including tenodesis of the long head of the biceps tendon. All patients were preoperatively assessed by clinical examination (Constant-Murley score [CMS]) and contrast-enhanced magnetic resonance arthrography. At 1 year of follow-up, specific clinical SSC tests, the CMS, and the loss of external rotation were evaluated. A native magnetic resonance investigation was performed to assess the structural integrity of the repair. The SSC muscle was compared with its preoperative condition regarding fatty infiltration and size (cross-sectional area). Patient satisfaction was graded from 1 (poor) to 4 (excellent). The mean time interval from trauma to surgery was 3.7 months. A concomitant lesion of the biceps tendon was observed in 10 patients (91%). The mean CMS improved from 44 to 89 points (P < .001). The functional tests showed a significant increase in strength (P < .05) (belly-press test, 4.8 v 2.9; lift-off test, 4.8 v 2.9). The mean loss of external rotation at 0° of abduction was 10° compared with the contralateral side (P < .05). Patient satisfaction was high. Magnetic resonance imaging evaluation showed complete structural integrity of the tendon repair in all studies. The SSC showed a significant decrease in fatty infiltration and increase in the cross-sectional area. Arthroscopic repair of higher-grade isolated SSC lesions provides reliable tendon healing accompanied by excellent functional results 1 year after surgery. Level IV, prospective therapeutic case series. Copyright © 2014 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

Powering a wireless sensor node with a vibration-driven piezoelectric energy harvester

NASA Astrophysics Data System (ADS)

Reilly, Elizabeth K.; Burghardt, Fred; Fain, Romy; Wright, Paul

2011-12-01

This paper discusses the direct application of scavenged energy to power a wireless sensor platform. A trapezoidal piezoelectric harvester was designed for a specific machine tool application and tested for robustness and longevity as well as performance. The design focused on resonant performance and distributed strain concentrations at a given resonant frequency and acceleration. Critical issues of power coupling and conditioning between harvester and wireless platform were addressed. The wireless platform consisted of a sensor, controller, power conditioning circuitry, and a custom low power radio. The system transmitted a sensor sample once every 10 s in a scavenging environment of 0.25 g and 100 Hz for a system duty cycle of approximately 0.2%.

Characterization and snubbing of a bidirectional MCT in a resonant ac link converter

NASA Technical Reports Server (NTRS)

Lee, Tony; Elbuluk, Malik E.; Zinger, Donald S.

1993-01-01

The MOS-Controlled Thyristor (MCT) is emerging as a powerful switch that combines the better characteristics of existing power devices. A study of switching stresses on an MCT switch under zero voltage resonant switching is presented. The MCT is used as a bidirectional switch in an ac/ac pulse density modulated inverter for induction motor drive. Current and voltage spikes are observed and analyzed with variations in the timing of the switching. Different snubber circuit configurations are under investigation to minimize the effect of these transients. The results will be extended to study and test the MCT switching in a medium power (5 hp) induction motor drive.

Heralded quantum controlled-phase gates with dissipative dynamics in macroscopically distant resonators

NASA Astrophysics Data System (ADS)

Qin, Wei; Wang, Xin; Miranowicz, Adam; Zhong, Zhirong; Nori, Franco

2017-07-01

Heralded near-deterministic multiqubit controlled-phase gates with integrated error detection have recently been proposed by Borregaard et al. [Phys. Rev. Lett. 114, 110502 (2015), 10.1103/PhysRevLett.114.110502]. This protocol is based on a single four-level atom (a heralding quartit) and N three-level atoms (operational qutrits) coupled to a single-resonator mode acting as a cavity bus. Here we generalize this method for two distant resonators without the cavity bus between the heralding and operational atoms. Specifically, we analyze the two-qubit controlled-Z gate and its multiqubit-controlled generalization (i.e., a Toffoli-like gate) acting on the two-lowest levels of N qutrits inside one resonator, with their successful actions being heralded by an auxiliary microwave-driven quartit inside the other resonator. Moreover, we propose a circuit-quantum-electrodynamics realization of the protocol with flux and phase qudits in linearly coupled transmission-line resonators with dissipation. These methods offer a quadratic fidelity improvement compared to cavity-assisted deterministic gates.

Creating and testing regulatory focus messages to enhance medication adherence.

PubMed

O'Connor, Ashley; Ladebue, Amy; Peterson, Jamie; Davis, Ryan; Jung Grant, Susan; McCreight, Marina; Lambert-Kerzner, Anne

2018-01-01

Objectives Strategies were explored to improve patient adherence to cardioprotective medications by borrowing from a motivational framework used in psychology, regulatory focus theory. The current study is part of a larger randomized control trial and was aimed at understanding what written educational messages, based on patients' regulatory focus tendency, resonated with each individual as a potential reminder to take medications. This study was also aimed at understanding why messages resonated with the patients. Methods Twenty veterans were tested for regulatory fitand presented with messages dependent on focus tendency. In-person semi-structured interviews were conducted to collect feedback of messages. An iterative analysis drawing primarily on matrix and reflexive team analyses was conducted. Result Six promotion and six prevention messages emerged, such as "team up with your provider to create a combination of medications to prevent illness" and "Live your best life - Take your medications". Five themes related to types of health messages that spoke to patients' regulatory fit were discovered: relatability; empowerment and control; philosophy on life; relationship with provider and medications; and vocabulary effect on the impact of messages. Discussion Motivational messages based on regulatory fit may be useful in improving patient medication adherence, leading to improved cardiovascular outcomes.

Morphometric magnetic resonance imaging and genetic testing in cerebellar abiotrophy in Arabian horses

PubMed Central

2013-01-01

Background Cerebellar abiotrophy (CA) is a rare but significant disease in Arabian horses caused by progressive death of the Purkinje cells resulting in cerebellar ataxia characterized by a typical head tremor, jerky head movements and lack of menace response. The specific role of magnetic resonance imaging (MRI) to support clinical diagnosis has been discussed. However, as yet MR imaging has only been described in one equine CA case. The role of MR morphometry in this regard is currently unknown. Due to the hereditary nature of the disease, genetic testing can support the diagnosis of CA. Therefore, the objective of this study was to perform MR morphometric analysis and genetic testing in four CA-affected Arabian horses and one German Riding Pony with purebred Arabian bloodlines in the third generation. Results CA was diagnosed pathohistologically in the five affected horses (2 months - 3 years) supported by clinical signs, necropsy, and genetic testing which confirmed the TOE1:g.2171G>A SNP genotype A/A in all CA-affected horses. On MR images morphometric analysis of the relative cerebellar size and relative cerebellar cerebrospinal fluid (CSF) space were compared to control images of 15 unaffected horses. It was demonstrated that in MR morphometric analyses, CA affected horses displayed a relatively smaller cerebellum compared to the entire brain mass than control animals (P = 0.0088). The relative cerebellar CSF space was larger in affected horses (P = 0.0017). Using a cut off value of 11.0% for relative cerebellar CSF space, the parameter differentiated between CA-affected horses and controls with a sensitivity of 100% and a specificity of 93.3%. Conclusions In conclusion, morphometric MRI and genetic analysis could be helpful to support the diagnosis of CA in vivo. PMID:23702154

Analysis and Design of High-Order Parallel Resonant Converters

NASA Astrophysics Data System (ADS)

Batarseh, Issa Eid

1990-01-01

In this thesis, a special state variable transformation technique has been derived for the analysis of high order dc-to-dc resonant converters. Converters comprised of high order resonant tanks have the advantage of utilizing the parasitic elements by making them part of the resonant tank. A new set of state variables is defined in order to make use of two-dimensional state-plane diagrams in the analysis of high order converters. Such a method has been successfully used for the analysis of the conventional Parallel Resonant Converters (PRC). Consequently, two -dimensional state-plane diagrams are used to analyze the steady state response for third and fourth order PRC's when these converters are operated in the continuous conduction mode. Based on this analysis, a set of control characteristic curves for the LCC-, LLC- and LLCC-type PRC are presented from which various converter design parameters are obtained. Various design curves for component value selections and device ratings are given. This analysis of high order resonant converters shows that the addition of the reactive components to the resonant tank results in converters with better performance characteristics when compared with the conventional second order PRC. Complete design procedure along with design examples for 2nd, 3rd and 4th order converters are presented. Practical power supply units, normally used for computer applications, were built and tested by using the LCC-, LLC- and LLCC-type commutation schemes. In addition, computer simulation results are presented for these converters in order to verify the theoretical results.

Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke

PubMed Central

Mair, Grant; von Kummer, Rüdiger; Adami, Alessandro; White, Philip M.; Adams, Matthew E.; Yan, Bernard; Demchuk, Andrew M.; Farrall, Andrew J.; Sellar, Robin J.; Sakka, Eleni; Palmer, Jeb; Perry, David; Lindley, Richard I.; Sandercock, Peter A.G.

2017-01-01

Background and Purpose— Computed tomographic angiography and magnetic resonance angiography are used increasingly to assess arterial patency in patients with ischemic stroke. We determined which baseline angiography features predict response to intravenous thrombolytics in ischemic stroke using randomized controlled trial data. Methods— We analyzed angiograms from the IST-3 (Third International Stroke Trial), an international, multicenter, prospective, randomized controlled trial of intravenous alteplase. Readers, masked to clinical, treatment, and outcome data, assessed prerandomization computed tomographic angiography and magnetic resonance angiography for presence, extent, location, and completeness of obstruction and collaterals. We compared angiography findings to 6-month functional outcome (Oxford Handicap Scale) and tested for interactions with alteplase, using ordinal regression in adjusted analyses. We also meta-analyzed all available angiography data from other randomized controlled trials of intravenous thrombolytics. Results— In IST-3, 300 patients had prerandomization angiography (computed tomographic angiography=271 and magnetic resonance angiography=29). On multivariable analysis, more extensive angiographic obstruction and poor collaterals independently predicted poor outcome (P<0.01). We identified no significant interaction between angiography findings and alteplase effect on Oxford Handicap Scale (P≥0.075) in IST-3. In meta-analysis (5 trials of alteplase or desmoteplase, including IST-3, n=591), there was a significantly increased benefit of thrombolytics on outcome (odds ratio>1 indicates benefit) in patients with (odds ratio, 2.07; 95% confidence interval, 1.18–3.64; P=0.011) versus without (odds ratio, 0.88; 95% confidence interval, 0.58–1.35; P=0.566) arterial obstruction (P for interaction 0.017). Conclusions— Intravenous thrombolytics provide benefit to stroke patients with computed tomographic angiography or magnetic resonance angiography evidence of arterial obstruction, but the sample was underpowered to demonstrate significant treatment benefit or harm among patients with apparently patent arteries. Clinical Trial Registration— URL: http://www.isrctn.com. Unique identifier: ISRCTN25765518. PMID:28008093

Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke.

PubMed

Mair, Grant; von Kummer, Rüdiger; Adami, Alessandro; White, Philip M; Adams, Matthew E; Yan, Bernard; Demchuk, Andrew M; Farrall, Andrew J; Sellar, Robin J; Sakka, Eleni; Palmer, Jeb; Perry, David; Lindley, Richard I; Sandercock, Peter A G; Wardlaw, Joanna M

2017-02-01

Computed tomographic angiography and magnetic resonance angiography are used increasingly to assess arterial patency in patients with ischemic stroke. We determined which baseline angiography features predict response to intravenous thrombolytics in ischemic stroke using randomized controlled trial data. We analyzed angiograms from the IST-3 (Third International Stroke Trial), an international, multicenter, prospective, randomized controlled trial of intravenous alteplase. Readers, masked to clinical, treatment, and outcome data, assessed prerandomization computed tomographic angiography and magnetic resonance angiography for presence, extent, location, and completeness of obstruction and collaterals. We compared angiography findings to 6-month functional outcome (Oxford Handicap Scale) and tested for interactions with alteplase, using ordinal regression in adjusted analyses. We also meta-analyzed all available angiography data from other randomized controlled trials of intravenous thrombolytics. In IST-3, 300 patients had prerandomization angiography (computed tomographic angiography=271 and magnetic resonance angiography=29). On multivariable analysis, more extensive angiographic obstruction and poor collaterals independently predicted poor outcome (P<0.01). We identified no significant interaction between angiography findings and alteplase effect on Oxford Handicap Scale (P≥0.075) in IST-3. In meta-analysis (5 trials of alteplase or desmoteplase, including IST-3, n=591), there was a significantly increased benefit of thrombolytics on outcome (odds ratio>1 indicates benefit) in patients with (odds ratio, 2.07; 95% confidence interval, 1.18-3.64; P=0.011) versus without (odds ratio, 0.88; 95% confidence interval, 0.58-1.35; P=0.566) arterial obstruction (P for interaction 0.017). Intravenous thrombolytics provide benefit to stroke patients with computed tomographic angiography or magnetic resonance angiography evidence of arterial obstruction, but the sample was underpowered to demonstrate significant treatment benefit or harm among patients with apparently patent arteries. URL: http://www.isrctn.com. Unique identifier: ISRCTN25765518. © 2016 The Authors.

Method and apparatus for sensing a target characteristic by measuring both impedance and resonant frequency of a tank circuit

NASA Technical Reports Server (NTRS)

Laskowski, Edward L. (Inventor)

1995-01-01

An apparatus for sensing a target characteristic, such as relative distance between the apparatus and target, target thickness, target material, or lateral position between the apparatus and the target, includes a coil for directing an electro-magnetic field at the target. A voltage controlled oscillator energizes the coil at a resonant frequency which is functionally related to the target characteristic. The coil has an effective impedance value at resonance functionally related to the target characteristic. A frequency monitor measures the resonant frequency. An impedance monitor determines the impedance value when the drive frequency is at the resonant value. A PROM or controller determines the target characteristic in response to the measured resonant frequency and the determined impedance value. The PROM or controller provides a signal responsive to the determined target characteristic.

A closed-loop system for frequency tracking of piezoresistive cantilever sensors

NASA Astrophysics Data System (ADS)

Wasisto, Hutomo Suryo; Zhang, Qing; Merzsch, Stephan; Waag, Andreas; Peiner, Erwin

2013-05-01

A closed loop circuit capable of tracking resonant frequencies for MEMS-based piezoresistive cantilever resonators is developed in this work. The proposed closed-loop system is mainly based on a phase locked loop (PLL) circuit. In order to lock onto the resonant frequency of the resonator, an actuation signal generated from a voltage-controlled oscillator (VCO) is locked to the phase of the input reference signal of the cantilever sensor. In addition to the PLL component, an instrumentation amplifier and an active low pass filter (LPF) are connected to the system for gaining the amplitude and reducing the noise of the cantilever output signals. The LPF can transform a rectangular signal into a sinusoidal signal with voltage amplitudes ranging from 5 to 10 V which are sufficient for a piezoactuator input (i.e., maintaining a large output signal of the cantilever sensor). To demonstrate the functionality of the system, a self-sensing silicon cantilever resonator with a built-in piezoresistive Wheatstone bridge is fabricated and integrated with the circuit. A piezoactuator is utilized for actuating the cantilever into resonance. Implementation of this closed loop system is used to track the resonant frequency of a silicon cantilever-based sensor resonating at 9.4 kHz under a cross-sensitivity test of ambient temperature. The changes of the resonant frequency are interpreted using a frequency counter connected to the system. From the experimental results, the temperature sensitivity and coefficient of the employed sensor are 0.3 Hz/°C and 32.8 ppm/°C, respectively. The frequency stability of the system can reach up to 0.08 Hz. The development of this system will enable real-time nanoparticle monitoring systems and provide a miniaturization of the instrumentation modules for cantilever-based nanoparticle detectors.

Emission wavelength tuning of fluorescence by fine structural control of optical metamaterials with Fano resonance

PubMed Central

Moritake, Y.; Kanamori, Y.; Hane, K.

2016-01-01

We demonstrated fine emission wavelength tuning of quantum dot (QD) fluorescence by fine structural control of optical metamaterials with Fano resonance. An asymmetric-double-bar (ADB), which was composed of only two bars with slightly different bar lengths, was used to obtain Fano resonance in the optical region. By changing the short bar length of ADB structures with high dimensional accuracy in the order of 10 nm, resonant wavelengths of Fano resonance were controlled from 1296 to 1416 nm. Fluorescence of QDs embedded in a polymer layer on ADB metamaterials were modified due to coupling to Fano resonance and fine tuning from 1350 to 1376 nm was observed. Wavelength tuning of modified fluorescence was reproduced by analysis using absorption peaks of Fano resonance. Tuning range of modified fluorescence became narrow, which was interpreted by a simple Gaussian model and resulted from comparable FWHM in QD fluorescence and Fano resonant peaks. The results will help the design and fabrication of metamaterial devices with fluorophores such as light sources and biomarkers. PMID:27622503

Testing of qubit materials and fabrication using superconducting resonators

NASA Astrophysics Data System (ADS)

Kumar, Shwetank; Steffen, Matthias; Divincenzo, David; Keefe, George; Rothwell, Mary Beth; Farinelli, Matthew; Rozen, Jim; Milliken, Frank; Ketchen, Mark

2009-03-01

We will present the results of measurements made on superconducting resonators fabricated using different substrates and superconducting metals. Specifically, the quality factor of these resonators will be shown to be closely related to not only the purity of the substrates and metals used in the process but also to the details of the fabrication. We will demonstrate the change in quality factor of a bare resonator when subjected to the qubit process. Based on our measurements we propose that superconducting resonators may form a test bed for troubleshooting the fabrication process for minimizing the materials related dissipation in the qubits.

Acoustic plane waves normally incident on a clamped panel in a rectangular duct. [to explain noise reduction curves for reducing interior noise in aircraft

NASA Technical Reports Server (NTRS)

Unz, H.; Roskam, J.

1979-01-01

The theory of acoustic plane wave normally incident on a clamped panel in a rectangular duct is developed. The coupling theory between the elastic vibrations of the panel (plate) and the acoustic wave propagation in infinite space and in the rectangular duct is considered. The partial differential equation which governs the vibration of the panel (plate) is modified by adding to its stiffness (spring) forces and damping forces, and the fundamental resonance frequency and the attenuation factor are discussed. The noise reduction expression based on the theory is found to agree well with the corresponding experimental data of a sample aluminum panel in the mass controlled region, the damping controlled region, and the stiffness controlled region. All the frequency positions of the upward and downward resonance spikes in the sample experimental data are identified theoretically as resulting from four cross interacting major resonance phenomena: the cavity resonance, the acoustic resonance, the plate resonance, and the wooden back panel resonance.

A model for active control of helicopter air resonance in hover and forward flight

NASA Technical Reports Server (NTRS)

Takahashi, M. D.; Friedmann, P. P.

1988-01-01

A coupled rotor/fuselage helicopter analysis is presented. The accuracy of the model is verified by comparing it with the experimental data. The sensitivity of the open loop damping of the unstable air resonance mode to such modeling effects as blade torsional flexibility, unsteady aerodynamics, forward flight, periodic terms, and trim solution is illustrated by numerous examples. Subsequently, the model is used in conjunction with linear optimal control theory to stabilize the air resonance mode. The influence of the modeling effects mentioned before on active air resonance control is then investigated.

Diagnostic value of three-dimensional magnetic resonance imaging of inner ear after intratympanic gadolinium injection, and clinical application of magnetic resonance imaging scoring system in patients with delayed endolymphatic hydrops.

PubMed

Gu, X; Fang, Z-M; Liu, Y; Lin, S-L; Han, B; Zhang, R; Chen, X

2014-01-01

Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging of the inner ear after intratympanic injection of gadolinium, together with magnetic resonance imaging scoring of the perilymphatic space, were used to investigate the positive identification rate of hydrops and determine the technique's diagnostic value for delayed endolymphatic hydrops. Twenty-five patients with delayed endolymphatic hydrops underwent pure tone audiometry, bithermal caloric testing, vestibular-evoked myogenic potential testing and three-dimensional magnetic resonance imaging of the inner ear after bilateral intratympanic injection of gadolinium. The perilymphatic space of the scanned images was analysed to investigate the positive identification rate of endolymphatic hydrops. According to the magnetic resonance imaging scoring of the perilymphatic space and the diagnostic standard, 84 per cent of the patients examined had endolymphatic hydrops. In comparison, the positive identification rates for vestibular-evoked myogenic potential and bithermal caloric testing were 52 per cent and 72 per cent respectively. Three-dimensional magnetic resonance imaging after intratympanic injection of gadolinium is valuable in the diagnosis of delayed endolymphatic hydrops and its classification. The perilymphatic space scoring system improved the diagnostic accuracy of magnetic resonance imaging.

Study of the damping characteristics of general aviation aircraft panels and development of computer programs to calculate the effectiveness of interior noise control treatment, part 1

NASA Technical Reports Server (NTRS)

Navaneethan, R.; Hunt, J.; Quayle, B.

1982-01-01

Tests were carried out on 20 inch x 20 inch panels at different test conditions using free-free panels, clamped panels, and panels as installed in the KU-FRL acoustic test facility. Tests with free-free panels verified the basic equipment set-up and test procedure. They also provided a basis for comparison. The results indicate that the effect of installed panels is to increase the damping ratio at the same frequency. However, a direct comparison is not possible, as the fundamental frequency of a free-free panel differs from the resonance frequency of the panel when installed. The damping values of panels installed in the test facility are closer to the damping values obtained with fixed-fixed panels. Effects of damping tape, stiffeners, and bonded and riveted edged conditions were also investigated. Progress in the development of a simple interior noise level control program is reported.

Human cartilage repair with a photoreactive adhesive-hydrogel composite.

PubMed

Sharma, Blanka; Fermanian, Sara; Gibson, Matthew; Unterman, Shimon; Herzka, Daniel A; Cascio, Brett; Coburn, Jeannine; Hui, Alexander Y; Marcus, Norman; Gold, Garry E; Elisseeff, Jennifer H

2013-01-09

Surgical options for cartilage resurfacing may be significantly improved by advances and application of biomaterials that direct tissue repair. A poly(ethylene glycol) diacrylate (PEGDA) hydrogel was designed to support cartilage matrix production, with easy surgical application. A model in vitro system demonstrated deposition of cartilage-specific extracellular matrix in the hydrogel biomaterial and stimulation of adjacent cartilage tissue development by mesenchymal stem cells. For translation to the joint environment, a chondroitin sulfate adhesive was applied to covalently bond and adhere the hydrogel to cartilage and bone tissue in articular defects. After preclinical testing in a caprine model, a pilot clinical study was initiated where the biomaterials system was combined with standard microfracture surgery in 15 patients with focal cartilage defects on the medial femoral condyle. Control patients were treated with microfracture alone. Magnetic resonance imaging showed that treated patients achieved significantly higher levels of tissue fill compared to controls. Magnetic resonance spin-spin relaxation times (T(2)) showed decreasing water content and increased tissue organization over time. Treated patients had less pain compared with controls, whereas knee function [International Knee Documentation Committee (IKDC)] scores increased to similar levels between the groups over the 6 months evaluated. No major adverse events were observed over the study period. With further clinical testing, this practical biomaterials strategy has the potential to improve the treatment of articular cartilage defects.

Magnetic resonance imaging volume of the angular gyri predicts financial skill deficits in people with amnestic mild cognitive impairment.

PubMed

Griffith, H Randall; Stewart, Christopher C; Stoeckel, Luke E; Okonkwo, Ozioma C; den Hollander, Jan A; Martin, Roy C; Belue, Katherine; Copeland, Jacquelynn N; Harrell, Lindy E; Brockington, John C; Clark, David G; Marson, Daniel C

2010-02-01

To better understand how brain atrophy in amnestic mild cognitive impairment (MCI) as measured using magnetic resonance imaging (MRI) volumetrics could affect instrumental activities of daily living (IADLs) such as financial abilities. Controlled, matched-sample, cross-sectional analysis regressing MRI volumetrics with financial performance measures. University medical and research center. Thirty-eight people with MCI and 28 older adult controls. MRI volumetric measurement of the hippocampi, angular gyri, precunei, and medial frontal lobes. Participants also completed neuropsychological tests and the Financial Capacity Instrument (FCI). Correlations were performed between FCI scores and MRI volumes in the group with MCI. People with MCI performed significantly below controls on the FCI and had significantly smaller hippocampi. Among people with MCI, performance on the FCI was moderately correlated with angular gyri and precunei volumes. Regression models demonstrated that angular gyrus volumes were predictive of FCI scores. Tests of mediation showed that measures of arithmetic and possibly attention partially mediated the relationship between angular gyrus volume and FCI score. Impaired financial abilities in amnestic MCI correspond with volume of the angular gyri as mediated by arithmetic knowledge. The findings suggest that early neuropathology within the lateral parietal region in MCI leads to a breakdown of cognitive abilities that affect everyday financial skills. The findings have implications for diagnosis and clinical care of people with MCI and AD.

Evaluation of magnetic resonance imaging for the differentiation of inflammatory, neoplastic, and vascular intradural spinal cord diseases in the dog.

PubMed

Masciarelli, Amanda E; Griffin, John F; Fosgate, Geoffrey T; Hecht, Silke; Mankin, Joseph M; Holmes, Shannon P; Platt, Simon R; Kent, Marc; Pancotto, Theresa E; Chen, Annie V; Levine, Jonathan M

2017-07-01

Magnetic resonance imaging (MRI) is a common test for dogs with suspected intradural spinal cord lesions, however studies on diagnostic performance for this test are lacking. Objectives of this multi-institutional, retrospective, case-control study were to estimate sensitivity and specificity of MRI for (1) distinguishing between histopathologically confirmed intradural spinal cord disease versus degenerative myelopathy in dogs, (2) categorizing intradural spinal cord diseases as neoplastic, inflammatory, or vascular; and (3) determining tumor type within the etiologic category of neoplasia. Additional aims were to (1) determine whether knowledge of clinical data affects sensitivity and specificity of MRI diagnoses; and (2) report interrater agreement for MRI classification of intradural spinal lesions. Cases were recruited from participating hospital databases over a 7-year period. Three reviewers independently evaluated each MRI study prior to and after provision of clinical information. A total of 87 cases were sampled (17 degenerative myelopathy, 53 neoplasia, nine inflammatory, and eight vascular). Magnetic resonance imaging had excellent (>97.6%) sensitivity for diagnosis of intradural spinal cord lesions but specificity varied before and after provision of clinical data (68.6% vs. 82.4%, P = 0.023). Magnetic resonance imaging had good sensitivity (86.8%) and moderate specificity (64.7-72.5%) for diagnosing neoplasia. Sensitivity was lower for classifying inflammatory lesions but improved with provision of clinical data (48.1% vs. 81.5%, P = 0.015). Magnetic resonance imaging was insensitive for diagnosing vascular lesions (25.0%). Interrater agreement was very good for correctly diagnosing dogs with intradural lesions (ĸ = 0.882-0.833), and good (ĸ = 0.726-0.671) for diagnosing dogs with neoplasia. © 2017 American College of Veterinary Radiology.

Two-motor direct drive control for elevation axis of telescope

NASA Astrophysics Data System (ADS)

Tang, T.; Tan, Y.; Ren, G.

2014-07-01

Two-motor application has become a very attractive filed in important field which high performance is permitted to achieve of position, speed, and acceleration. In the elevation axis of telescope control system, two-motor direct drive is proposed to enhance the high performance of tracking control system. Although there are several dominant strengths such as low size of motors and high torsional structural dynamics, the synchronization control of two motors is a very difficult and important. In this paper, a multi-loop control technique base master-slave current control is used to synchronize two motors, including current control loop, speed control loop and position control loop. First, the direct drive function of two motors is modeled. Compared of single motor direct control system, the resonance frequency of two motor control systems is same; while the anti-resonance frequency of two motors control system is 1.414 times than those of sing motor system. Because of rigid coupling for direct drive, the speed of two motor of the system is same, and the synchronization of torque for motors is critical. The current master-slave control technique is effective to synchronize the torque, which the current loop of the master motors is tracked the other slave motor. The speed feedback into the input of current loop of the master motors. The experiments test the performance of the two motors drive system. The random tracking error is 0.0119" for the line trajectory of 0.01°/s.

14 CFR 29.663 - Ground resonance prevention means.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ground resonance prevention means. 29.663... Ground resonance prevention means. (a) The reliability of the means for preventing ground resonance must... or tests that malfunction or failure of a single means will not cause ground resonance. (b) The...

14 CFR 29.663 - Ground resonance prevention means.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground resonance prevention means. 29.663... Ground resonance prevention means. (a) The reliability of the means for preventing ground resonance must... or tests that malfunction or failure of a single means will not cause ground resonance. (b) The...

Acoustic evaluation of the Helmholtz resonator treatment in the NASA Lewis 8- by 6-foot supersonic wind tunnel

NASA Technical Reports Server (NTRS)

Heidelberg, Laurence J.; Gordon, Elliot B.

1989-01-01

The acoustic consequences of sealing the Helmholtz resonators of the NASA Lewis 8- by 6-Foot Supersonic Wind Tunnel (8x6 SWT) were experimentally evaluated. This resonator sealing was proposed in order to avoid entrapment of hydrogen during tests of advanced hydrogen-fueled engines. The resonators were designed to absorb energy in the 4- to 20-Hz range; thus, this investigation is primarily concerned with infrasound. Limited internal and external noise measurements were made at tunnel Mach numbers ranging from 0.5 to 2.0. Although the resonators were part of the acoustic treatment installed because of a community noise problem their sealing did not seem to indicate a reoccurrence of the problem would result. Two factors were key to this conclusion: (1) A large bulk treatment muffler downstream of the resonators was able to make up for much of the attenuation originally provided by the resonators, and (2) there was no noise source in the tunnel test section. The previous community noise problem occurred when a large ramjet was tested in an open-loop tunnel configuration. If a propulsion system producing high noise levels at frequencies of less than 10 Hz were tested, the conclusion on community noise would have to be reevaluated.

Development of advanced magnetic resonance sensor for industrial applications. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Los Santos, A.

1997-06-01

Southwest Research Institute (SwRI) and various subcontractors, in a cooperative agreement with the DOE, have developed and tested an advanced magnetic resonance (MR) sensor for several industrial applications and made various market surveys. The original goal of the program was to develop an advanced moisture sensor to allow more precise and rapid control of drying processes so that energy and/or product would not be wasted. Over the course of the program, it was shown that energy savings were achievable but in many processes the return in investment did not justify the cost of a magnetic resonance sensor. However, in manymore » processes, particularly chemical, petrochemical, paper and others, the return in investment can be very high as to easily justify the cost of a magnetic resonance sensor. In these industries, substantial improvements in product yield, quality, and efficiency in production can cause substantial energy savings and reductions in product wastage with substantial environmental effects. The initial applications selected for this program included measurement of corn gluten at three different points and corn germ at one point in an American Maize corn processing plant. During the initial phases (I and II) of this program, SwRI developed a prototype advanced moisture sensor utilizing NMR technology capable of accurately and reliably measuring moisture in industrial applications and tested the sensor in the laboratory under conditions simulating on-line products in the corn wet milling industry. The objective of Phase III was to test the prototype sensor in the plant environment to determine robustness, reliability and long term stability. Meeting these objectives would permit extended field testing to improve the statistical database used to calibrate the sensor and subject the sensor to true variations in operating conditions encountered in the process rather than those which could only be simulated in the laboratory.« less

Non-invasive assessment of pulsatile intracranial pressure with phase-contrast magnetic resonance imaging

PubMed Central

Lindstrøm, Erika Kristina; Vatnehol, Svein Are Sirirud; Mardal, Kent-André; Emblem, Kyrre Eeg; Eide, Per Kristian

2017-01-01

Invasive monitoring of pulsatile intracranial pressure can accurately predict shunt response in patients with idiopathic normal pressure hydrocephalus, but may potentially cause complications such as bleeding and infection. We tested how a proposed surrogate parameter for pulsatile intracranial pressure, the phase-contrast magnetic resonance imaging derived pulse pressure gradient, compared with its invasive counterpart. In 22 patients with suspected idiopathic normal pressure hydrocephalus, preceding invasive intracranial pressure monitoring, and any surgical shunt procedure, we calculated the pulse pressure gradient from phase-contrast magnetic resonance imaging derived cerebrospinal fluid flow velocities obtained at the upper cervical spinal canal using a simplified Navier-Stokes equation. Repeated measurements of the pulse pressure gradient were also undertaken in four healthy controls. Of 17 shunted patients, 16 responded, indicating high proportion of “true” normal pressure hydrocephalus in the patient cohort. However, there was no correlation between the magnetic resonance imaging derived pulse pressure gradient and pulsatile intracranial pressure (R = -.18, P = .43). Pulse pressure gradients were also similar in patients and healthy controls (P = .26), and did not differ between individuals with pulsatile intracranial pressure above or below established thresholds for shunt treatment (P = .97). Assessment of pulse pressure gradient at level C2 was therefore not found feasible to replace invasive monitoring of pulsatile intracranial pressure in selection of patients with idiopathic normal pressure hydrocephalus for surgical shunting. Unlike invasive, overnight monitoring, the pulse pressure gradient from magnetic resonance imaging comprises short-term pressure fluctuations only. Moreover, complexity of cervical cerebrospinal fluid flow and -pulsatility at the upper cervical spinal canal may render the pulse pressure gradient a poor surrogate marker for intracranial pressure pulsations. PMID:29190788

Non-invasive assessment of pulsatile intracranial pressure with phase-contrast magnetic resonance imaging.

PubMed

Ringstad, Geir; Lindstrøm, Erika Kristina; Vatnehol, Svein Are Sirirud; Mardal, Kent-André; Emblem, Kyrre Eeg; Eide, Per Kristian

2017-01-01

Invasive monitoring of pulsatile intracranial pressure can accurately predict shunt response in patients with idiopathic normal pressure hydrocephalus, but may potentially cause complications such as bleeding and infection. We tested how a proposed surrogate parameter for pulsatile intracranial pressure, the phase-contrast magnetic resonance imaging derived pulse pressure gradient, compared with its invasive counterpart. In 22 patients with suspected idiopathic normal pressure hydrocephalus, preceding invasive intracranial pressure monitoring, and any surgical shunt procedure, we calculated the pulse pressure gradient from phase-contrast magnetic resonance imaging derived cerebrospinal fluid flow velocities obtained at the upper cervical spinal canal using a simplified Navier-Stokes equation. Repeated measurements of the pulse pressure gradient were also undertaken in four healthy controls. Of 17 shunted patients, 16 responded, indicating high proportion of "true" normal pressure hydrocephalus in the patient cohort. However, there was no correlation between the magnetic resonance imaging derived pulse pressure gradient and pulsatile intracranial pressure (R = -.18, P = .43). Pulse pressure gradients were also similar in patients and healthy controls (P = .26), and did not differ between individuals with pulsatile intracranial pressure above or below established thresholds for shunt treatment (P = .97). Assessment of pulse pressure gradient at level C2 was therefore not found feasible to replace invasive monitoring of pulsatile intracranial pressure in selection of patients with idiopathic normal pressure hydrocephalus for surgical shunting. Unlike invasive, overnight monitoring, the pulse pressure gradient from magnetic resonance imaging comprises short-term pressure fluctuations only. Moreover, complexity of cervical cerebrospinal fluid flow and -pulsatility at the upper cervical spinal canal may render the pulse pressure gradient a poor surrogate marker for intracranial pressure pulsations.

Circuit weight training and cardiac morphology: a trial with magnetic resonance imaging.

PubMed

Camargo, M D; Stein, R; Ribeiro, J P; Schvartzman, P R; Rizzatti, M O; Schaan, B D

2008-02-01

Aerobic training (AT) and circuit weight training (CWT) improve peak oxygen uptake (VO(2)peak). During CWT the circulatory system is exposed to higher pressure, which could induce left ventricle morphological adaptations, possibly distinct from those derived from aerobic training. To compare the effects of aerobic training and CWT upon morphological and functional cardiac adaptations detected by magnetic resonance imaging. Twenty healthy sedentary individuals were randomly assigned to participate in a 12-week programme of aerobic training (n = 6), CWR (n = 7) or no intervention (n = 7, controls). Training programmes consisted of 36 sessions, 35 min each, 3 times per week, at 70% of maximal heart rate, and CWT included series of resistance exercises performed at 60% of 1 maximal repetition. Cardiopulmonary exercise testing and cardiac magnetic resonance imaging were performed before and after the intervention. There was a similar improvement in VO(2)peak following aerobic training (mean (SD) increment: 12 (4)%) and CWT (12 (4)%), while there was no change in the control group. Aerobic training (12 (6)%) and CWT (16 (5)%) improved strength in the lower limbs, and only CWT resulted in improvement of 13 (4)% in the strength of the upper limbs. However, there were no detectable changes in left ventricular mass, end-diastolic volume, stroke volume or ejection fraction. In previously sedentary individuals, short-term CWT and aerobic training induce similar improvement in functional capacity without any adaptation in cardiac morphology detectable by cardiac magnetic resonance imaging.

Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease.

PubMed

Rolinski, Michal; Griffanti, Ludovica; Piccini, Paola; Roussakis, Andreas A; Szewczyk-Krolikowski, Konrad; Menke, Ricarda A; Quinnell, Timothy; Zaiwalla, Zenobia; Klein, Johannes C; Mackay, Clare E; Hu, Michele T M

2016-08-01

SEE POSTUMA DOI101093/AWW131 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: Resting state functional magnetic resonance imaging dysfunction within the basal ganglia network is a feature of early Parkinson's disease and may be a diagnostic biomarker of basal ganglia dysfunction. Currently, it is unclear whether these changes are present in so-called idiopathic rapid eye movement sleep behaviour disorder, a condition associated with a high rate of future conversion to Parkinson's disease. In this study, we explore the utility of resting state functional magnetic resonance imaging to detect basal ganglia network dysfunction in rapid eye movement sleep behaviour disorder. We compare these data to a set of healthy control subjects, and to a set of patients with established early Parkinson's disease. Furthermore, we explore the relationship between resting state functional magnetic resonance imaging basal ganglia network dysfunction and loss of dopaminergic neurons assessed with dopamine transporter single photon emission computerized tomography, and perform morphometric analyses to assess grey matter loss. Twenty-six patients with polysomnographically-established rapid eye movement sleep behaviour disorder, 48 patients with Parkinson's disease and 23 healthy control subjects were included in this study. Resting state networks were isolated from task-free functional magnetic resonance imaging data using dual regression with a template derived from a separate cohort of 80 elderly healthy control participants. Resting state functional magnetic resonance imaging parameter estimates were extracted from the study subjects in the basal ganglia network. In addition, eight patients with rapid eye movement sleep behaviour disorder, 10 with Parkinson's disease and 10 control subjects received (123)I-ioflupane single photon emission computerized tomography. We tested for reduction of basal ganglia network connectivity, and for loss of tracer uptake in rapid eye movement sleep behaviour disorder and Parkinson's disease relative to each other and to controls. Connectivity measures of basal ganglia network dysfunction differentiated both rapid eye movement sleep behaviour disorder and Parkinson's disease from controls with high sensitivity (96%) and specificity (74% for rapid eye movement sleep behaviour disorder, 78% for Parkinson's disease), indicating its potential as an indicator of early basal ganglia dysfunction. Rapid eye movement sleep behaviour disorder was indistinguishable from Parkinson's disease on resting state functional magnetic resonance imaging despite obvious differences on dopamine transported single photon emission computerized tomography. Basal ganglia connectivity is a promising biomarker for the detection of early basal ganglia network dysfunction, and may help to identify patients at risk of developing Parkinson's disease in the future. Future risk stratification using a polymodal approach could combine basal ganglia network connectivity with clinical and other imaging measures, with important implications for future neuroprotective trials in rapid eye movement sleep behaviour disorder. © The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain.

Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson’s disease

PubMed Central

Rolinski, Michal; Griffanti, Ludovica; Piccini, Paola; Roussakis, Andreas A.; Szewczyk-Krolikowski, Konrad; Menke, Ricarda A.; Quinnell, Timothy; Zaiwalla, Zenobia; Klein, Johannes C.; Mackay, Clare E.

2016-01-01

Abstract See Postuma (doi:10.1093/aww131) for a scientific commentary on this article. Resting state functional magnetic resonance imaging dysfunction within the basal ganglia network is a feature of early Parkinson’s disease and may be a diagnostic biomarker of basal ganglia dysfunction. Currently, it is unclear whether these changes are present in so-called idiopathic rapid eye movement sleep behaviour disorder, a condition associated with a high rate of future conversion to Parkinson’s disease. In this study, we explore the utility of resting state functional magnetic resonance imaging to detect basal ganglia network dysfunction in rapid eye movement sleep behaviour disorder. We compare these data to a set of healthy control subjects, and to a set of patients with established early Parkinson’s disease. Furthermore, we explore the relationship between resting state functional magnetic resonance imaging basal ganglia network dysfunction and loss of dopaminergic neurons assessed with dopamine transporter single photon emission computerized tomography, and perform morphometric analyses to assess grey matter loss. Twenty-six patients with polysomnographically-established rapid eye movement sleep behaviour disorder, 48 patients with Parkinson’s disease and 23 healthy control subjects were included in this study. Resting state networks were isolated from task-free functional magnetic resonance imaging data using dual regression with a template derived from a separate cohort of 80 elderly healthy control participants. Resting state functional magnetic resonance imaging parameter estimates were extracted from the study subjects in the basal ganglia network. In addition, eight patients with rapid eye movement sleep behaviour disorder, 10 with Parkinson’s disease and 10 control subjects received 123I-ioflupane single photon emission computerized tomography. We tested for reduction of basal ganglia network connectivity, and for loss of tracer uptake in rapid eye movement sleep behaviour disorder and Parkinson’s disease relative to each other and to controls. Connectivity measures of basal ganglia network dysfunction differentiated both rapid eye movement sleep behaviour disorder and Parkinson’s disease from controls with high sensitivity (96%) and specificity (74% for rapid eye movement sleep behaviour disorder, 78% for Parkinson’s disease), indicating its potential as an indicator of early basal ganglia dysfunction. Rapid eye movement sleep behaviour disorder was indistinguishable from Parkinson’s disease on resting state functional magnetic resonance imaging despite obvious differences on dopamine transported single photon emission computerized tomography. Basal ganglia connectivity is a promising biomarker for the detection of early basal ganglia network dysfunction, and may help to identify patients at risk of developing Parkinson’s disease in the future. Future risk stratification using a polymodal approach could combine basal ganglia network connectivity with clinical and other imaging measures, with important implications for future neuroprotective trials in rapid eye movement sleep behaviour disorder. PMID:27297241

Reward abnormalities among women with full and subthreshold bulimia nervosa: a functional magnetic resonance imaging study.

PubMed

Bohon, Cara; Stice, Eric

2011-11-01

To test the hypothesis that women with full and subthreshold bulimia nervosa show abnormal neural activation in response to food intake and anticipated food intake relative to healthy control women. Females with and without full/subthreshold bulimia nervosa recruited from the community (N = 26) underwent functional magnetic resonance imaging (fMRI) during receipt and anticipated receipt of chocolate milkshake and a tasteless control solution. Women with bulimia nervosa showed trends for less activation than healthy controls in the right anterior insula in response to anticipated receipt of chocolate milkshake (vs. tasteless solution) and in the left middle frontal gyrus, right posterior insula, right precentral gyrus, and right mid dorsal insula in response to consumptions of milkshake (vs. tasteless solution). Bulimia nervosa may be related to potential hypofunctioning of the brain reward system, which may lead these individuals to binge eat to compensate for this reward deficit, though the hypo-responsivity might be a result of a history of binge eating highly palatable foods. Copyright © 2010 Wiley Periodicals, Inc.

Reward Abnormalities Among Women with Full and Subthreshold Bulimia Nervosa: A Functional Magnetic Resonance Imaging Study

PubMed Central

Bohon, Cara; Stice, Eric

2010-01-01

Objective To test the hypothesis that women with full and subthreshold bulimia nervosa show abnormal neural activation in response to food intake and anticipated food intake relative to healthy control women. Method Females with and without full/subthreshold bulimia nervosa recruited from the community (N = 26) underwent functional magnetic resonance imaging (fMRI) during receipt and anticipated receipt of chocolate milkshake and a tasteless control solution. Results Women with bulimia nervosa showed trends for less activation than healthy controls in the right anterior insula in response to anticipated receipt of chocolate milkshake (versus tasteless solution) and in the left middle frontal gyrus, right posterior insula, right precentral gyrus, and right mid dorsal insula in response to consumptions of milkshake (versus tasteless solution). Discussion Bulimia nervosa may be related to potential hypo-functioning of the brain reward system, which may lead these individuals to binge eat to compensate for this reward deficit, though the hypo-responsivity might be a result of a history of binge eating highly palatable foods. PMID:21997421

TlCaBaCuO high Tc superconducting microstrip ring resonators designed for 12 GHz

NASA Technical Reports Server (NTRS)

Subramanyam, G.; Kapoor, V. J.; Chorey, C. M.; Bhasin, K. B.

1993-01-01

Microwave properties of sputtered Tl-Ca-Ba-Cu-O thin films were investigated by designing, fabricating, and testing microstrip ring resonators. Ring resonators designed for 12 GHz fundamental resonance frequency, were fabricated and tested. From the unloaded Q values for the resonators, the surface resistance was calculated by separating the conductor losses from the total losses. The penetration depth was obtained from the temperature dependence of resonance frequency, assuming that the shift in resonance frequency is mainly due to the temperature dependence of penetration depth. The effective surface resistance at 12 GHz and 77 K was determined to be between 1.5 and 2.75 mOmega, almost an order lower than Cu at the same temperature and frequency. The effective penetration depth at 0 K is approximately 7000 A.

Resonance controlled transport in phase space

NASA Astrophysics Data System (ADS)

Leoncini, Xavier; Vasiliev, Alexei; Artemyev, Anton

2018-02-01

We consider the mechanism of controlling particle transport in phase space by means of resonances in an adiabatic setting. Using a model problem describing nonlinear wave-particle interaction, we show that captures into resonances can be used to control transport in momentum space as well as in physical space. We design the model system to provide creation of a narrow peak in the distribution function, thus producing effective cooling of a sub-ensemble of the particles.

A silicon micromachined resonant pressure sensor

NASA Astrophysics Data System (ADS)

Tang, Zhangyang; Fan, Shangchun; Cai, Chenguang

2009-09-01

This paper describes the design, fabrication and test of a silicon micromachined resonant pressure sensor. A square membrane and a doubly clamped resonant beam constitute a compound structure. The former senses the pressure directly, while the latter changes its resonant frequency according to deformation of the membrane. The final output relation between the resonant frequency and the applied pressure is deducted according to the structure mechanical properties. Sensors are fabricated by micromachining technology, and then sealed in vaccum. These sensors are tested by open-loop and close-loop system designed on purpose. The experiment results demonstrate that the sensor has a sensitivity of 49.8Hz/kPa and repeatability of 0.08%.

Recent progress of TAMA300

NASA Astrophysics Data System (ADS)

Arai, K.; TAMA Collaboration

2008-07-01

Current effort of the TAMA project is focused on establishment of the interferometer operation with a new vibration isolation system, called 'Seismic Attenuation System' (SAS). The SAS employs a multiple stage structure to realize soft spring for all of directions, as well as utilizes active control systems to stabilize mechanical resonances in the low frequency region below 1 Hz. The SASs were installed for four test masses, resulting in improvement of cavity length fluctuation below 150 Hz. We describe the structure of the SAS and its local active control system, and the status of the interferometer.

Right Dorsolateral Frontal Lobe N-Acetyl Aspartate and Myoinositol Concentration Estimation in Type 2 Diabetes with Magnetic Resonance Spectroscopy.

PubMed

Nagothu, Rajani Santhakumari; Reddy, Yogananda Indla; Rajagopalan, Archana; Varma, Ravi

2015-07-01

Chronic hyperglycaemia in type 2 diabetes, effects the central nervous system by altering the concentrations of brain metabolites like N-acetyl aspartate (NAA) and myoinositol (mI), which are indicators of neuronal integrity and glial cell damage respectively. Dorsolateral frontal lobe is associated with aspects of cognition especially right frontal lobe is involved in episodic memory retrieval, ninety percent of the diabetic cases are type 2 in nature globally and yoga is very effective in stabilizing the brain metabolites by bringing the blood glucose levels to near or within the physiological range in type 2 diabetes. The aim of the study was to observe the effects of yogasana and pranayama on glycosilated haemoglobin (HbA1c) levels and right dorsolateral frontal cortical NAA and mI concentration in type 2 diabetic subjects. It's a case control study. Sixty eight type 2 diabetic subjects of both the sex, aged between 35-65 years are included in the study, subjects are divided in to test and control group 34 each. Test group subjects did the yogasana and pranayama for a period of 6 months, 6 days in a week, 45-60 minutes daily under the supervision of a qualified yoga teacher. Control group subjects are not on any specific exercise regimen. Both the group subjects are taking oral hypoglycaemic agents. HbA1c levels are measured using the Bio-Rad D-10™ haemoglobin A1c program and Magnetic Resonance Spectroscopy (MRS) is used in assessing the metabolite concentrations. Analysis of data was done by using unpaired t-test. P-value for HbA1c level is <0.001, which is highly significant statistically. P-value for NAA was < 0.02 and for myoinositol was < 0.01, which are statistically significant. HbA1c levels in control and test group subjects are 7.7 ± 1.84 and 6.02 ± 0.46 respectively. NAA concentrations in the right dorsolateral frontal lobe of control and test group are 1.44 ± 0.15 and 1.54 ± 0.19 respectively. The mI concentrations in the right dorsolateral frontal lobe of control and test group are 0.61 ± 0.22 and 0.47 ± 0.24 respectively. Yogasana and pranayama minimized the neuronal and glial cellular damage in test group, which is evident by minimal changes in right dorsolateral frontal lobe NAA and mI levels in type 2 diabetic subjects.

Investigation of aeroelastic stability phenomena of a helicopter by in-flight shake test

NASA Technical Reports Server (NTRS)

Miao, W. L.; Edwards, T.; Brandt, D. E.

1976-01-01

The analytical capability of the helicopter stability program is discussed. The parameters which are found to be critical to the air resonance characteristics of the soft in-plane hingeless rotor systems are detailed. A summary of two model test programs, a 1/13.8 Froude-scaled BO-105 model and a 1.67 meter (5.5 foot) diameter Froude-scaled YUH-61A model, are presented with emphasis on the selection of the final parameters which were incorporated in the full scale YUH-61A helicopter. Model test data for this configuration are shown. The actual test results of the YUH-61A air resonance in-flight shake test stability are presented. Included are a concise description of the test setup, which employs the Grumman Automated Telemetry System (ATS), the test technique for recording in-flight stability, and the test procedure used to demonstrate favorable stability characteristics with no in-plane damping augmentation (lag damper removed). The data illustrating the stability trend of air resonance with forward speed and the stability trend of ground resonance for percent airborne are presented.

Overview of Imaging Tests

MedlinePlus

... Overview of Imaging Tests Angiography Computed Tomography (CT) Magnetic Resonance Imaging (MRI) Plain X-Rays Radionuclide Scanning ... and radionuclide scanning Sound waves, as in ultrasonography Magnetic fields, as in magnetic resonance imaging (MRI) Substances ...

Resonant ultrasound spectroscopy and non-destructive testing

NASA Astrophysics Data System (ADS)

Migliori, A.; Darling, T. W.

The use of mechanical resonances to test properties of materials is perhaps older than the industrial revolution. Early documented cases of British railroad engineers tapping the wheels of a train and using the sound to detect cracks perhaps mark the first real use of resonances to test the integrity of high-performance alloys. Attempts were made in the following years to understand the resonances of solids mathematically, based on the shape and composition. But Nobel Laureate Lord Rayleigh best summarized the state of affairs in 1894, stating 'the problem has, for the most part, resisted attack'. More recently, modern computers and electronics have enabled Anderson and co-workers with their work on minerals, and our work at Los Alamos on new materials and manufactured components to advance the use of resonances to a precision non-destructive testing tool that makes anisotropic modulus measurements, defect detection and geometry error detection routine. The result is that resonances can achieve the highest absolute accuracy for any dynamic modulus measurement technique, can be used on the smallest samples, and can also enable detection of errors in certain classes of precision manufactured components faster and more accurately than any other technique.

Evidence for early neurodegeneration in the cervical cord of patients with primary progressive multiple sclerosis.

PubMed

Abdel-Aziz, Khaled; Schneider, Torben; Solanky, Bhavana S; Yiannakas, Marios C; Altmann, Dan R; Wheeler-Kingshott, Claudia A M; Peters, Amy L; Day, Brian L; Thompson, Alan J; Ciccarelli, Olga

2015-06-01

Spinal neurodegeneration is an important determinant of disability progression in patients with primary progressive multiple sclerosis. Advanced imaging techniques, such as single-voxel (1)H-magnetic resonance spectroscopy and q-space imaging, have increased pathological specificity for neurodegeneration, but are challenging to implement in the spinal cord and have yet to be applied in early primary progressive multiple sclerosis. By combining these imaging techniques with new clinical measures, which reflect spinal cord pathology more closely than conventional clinical tests, we explored the potential for spinal magnetic resonance spectroscopy and q-space imaging to detect early spinal neurodegeneration that may be responsible for clinical disability. Data from 21 patients with primary progressive multiple sclerosis within 6 years of disease onset, and 24 control subjects were analysed. Patients were clinically assessed on grip strength, vibration perception thresholds and postural stability, in addition to the Expanded Disability Status Scale, Nine Hole Peg Test, Timed 25-Foot Walk Test, Multiple Sclerosis Walking Scale-12, and Modified Ashworth Scale. All subjects underwent magnetic resonance spectroscopy and q-space imaging of the cervical cord and conventional brain and spinal magnetic resonance imaging at 3 T. Multivariate analyses and multiple regression models were used to assess the differences in imaging measures between groups and the relationship between magnetic resonance imaging measures and clinical scores, correcting for age, gender, spinal cord cross-sectional area, brain T2 lesion volume, and brain white matter and grey matter volume fractions. Although patients did not show significant cord atrophy when compared with healthy controls, they had significantly lower total N-acetyl-aspartate (mean 4.01 versus 5.31 mmol/l, P = 0.020) and glutamate-glutamine (mean 4.65 versus 5.93 mmol/l, P = 0.043) than controls. Patients showed an increase in q-space imaging-derived indices of perpendicular diffusivity in both the whole cord and major columns compared with controls (P < 0.05 for all indices). Lower total N-acetyl-aspartate was associated with higher disability, as assessed by the Expanded Disability Status Scale (coefficient = -0.41, 0.01 < P < 0.05), Modified Ashworth Scale (coefficient = -3.78, 0.01 < P < 0.05), vibration perception thresholds (coefficient = -4.37, P = 0.021) and postural sway (P < 0.001). Lower glutamate-glutamine predicted increased postural sway (P = 0.017). Increased perpendicular diffusivity in the whole cord and columns was associated with increased scores on the Modified Ashworth Scale, vibration perception thresholds and postural sway (P < 0.05 in all cases). These imaging findings indicate reduced structural integrity of neurons, demyelination, and abnormalities in the glutamatergic pathways in the cervical cord of early primary progressive multiple sclerosis, in the absence of extensive spinal cord atrophy. The observed relationship between imaging measures and disability suggests that early spinal neurodegeneration may underlie clinical impairment, and should be targeted in future clinical trials with neuroprotective agents to prevent the development of progressive disability. © The Author (2015). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Xiaoyong, E-mail: zhangxy@buaa.edu.cn, E-mail: yanxiaojun@buaa.edu.cn; Yan, Xiaojun, E-mail: zhangxy@buaa.edu.cn, E-mail: yanxiaojun@buaa.edu.cn; Collaborative Innovation Center of Advanced Aero-Engine, Beijing 100191

This note presents a component-level frequency tunable isolator for vibration-sensitive chips. The isolator employed 8 U-shaped shape memory alloy (SMA) beams to support an isolation island (used for mounting chips). Due to the temperature-induced Young’s modulus variation of SMA, the system stiffness of the isolator can be controlled through heating the SMA beams. In such a way, the natural frequency of the isolator can be tuned. A prototype was fabricated to evaluate the concept. The test results show that the natural frequency of the isolator can be tuned in the range of 64 Hz–97 Hz by applying different heating strategies.more » Moreover, resonant vibration can be suppressed significantly (the transmissibility decreases about 65% near the resonant frequency) using a real-time tuning method.« less

Cross-Talk in Superconducting Transmon Quantum Computing Architecture

NASA Astrophysics Data System (ADS)

Abraham, David; Chow, Jerry; Corcoles, Antonio; Rothwell, Mary; Keefe, George; Gambetta, Jay; Steffen, Matthias; IBM Quantum Computing Team

2013-03-01

Superconducting transmon quantum computing test structures often exhibit significant undesired cross-talk. For experiments with only a handful of qubits this cross-talk can be quantified and understood, and therefore corrected. As quantum computing circuits become more complex, and thereby contain increasing numbers of qubits and resonators, it becomes more vital that the inadvertent coupling between these elements is minimized. The task of accurately controlling each single qubit to the level of precision required throughout the realization of a quantum algorithm is difficult by itself, but coupled with the need of nulling out leakage signals from neighboring qubits or resonators would quickly become impossible. We discuss an approach to solve this critical problem. We acknowledge support from IARPA under contract W911NF-10-1-0324.

Optical micro resonance based sensor schemes for detection and identification of nano particles and biological agents in situ

NASA Astrophysics Data System (ADS)

Saetchnikov, Vladimir A.; Tcherniavskaia, Elina A.; Schweiger, Gustav; Ostendorf, Andreas

2010-05-01

A novel emerging technique for the label-free analysis of nano particles including biomolecules using optical micro cavity resonance is being developed. Various schemes based on a mechanically fixed microspheres as well as microspheres melted by laser on the tip of a standard single mode fiber have been investigated to make further development for microbial application. Water solutions of ethanol, HCl, glucose, vitamin C and biotin have been used to test refractive index changes by monitoring the magnitude of the whispering gallery modes spectral shift. Particular efforts were made for effective fixing of the micro spheres in the water flow, an optimal geometry for micro resonance observation and material of microsphere the most appropriate for microbial application. Optical resonance in free micro spheres from PMMA fixed in micro channels produced by photolithography has been observed under the laser power of less then 1 microwatt. Resonance shifts of C reactive protein water solutions as well as albumin solutions in pure water and with HCl modelling blood have been investigated. Introducing controlled amount of glass gel nano particles into sensor microsphere surrounding were accompanied by both correlative resonance shift (400 nm in diameter) and total reconstruct of resonance spectra (57 nm in diameter). Developed schemes have been demonstrated to be a promising technology platform for sensitive, lab-on-chip type sensor of diagnostic tools for different biological molecules, e.g. proteins, oligonucleotides, oligosaccharides, lipids, small molecules, viral particles, cells as well as in different experimental contexts e.g. proteomics, genomics, drug discovery, and membrane studies.

Results of the mission profile life test. [for J-series mercury ion engines

NASA Technical Reports Server (NTRS)

Bechtel, R. T.; Trump, G. E.; James, E. L.

1982-01-01

Seven J series 30-cm diameter thrusters have been tested in segments of up to 5,070 hr, for 14,541 hr in the Mission Profile Life Test facility. Test results have indicated the basic thruster design to be consistent with the lifetime goal of 15,000 hr at 2-A beam. The only areas of concern identified which appear to require additional verification testing involve contamination of mercury propellant isolators, which may be due to facility constituents, and the ability of specially covered surfaces to contain sputtered material and prevent flake formation. The ability of the SCR, series resonant inverter power processor to operate the J series thruster and autonomous computer control of the thruster/processor system were demonstrated.

Self-other resonance, its control and prosocial inclinations: Brain-behavior relationships.

PubMed

Christov-Moore, Leonardo; Iacoboni, Marco

2016-04-01

Humans seem to place a positive reward value on prosocial behavior. Evidence suggests that this prosocial inclination is driven by our reflexive tendency to share in the observed sensations, emotions and behavior of others, or "self-other resonance". In this study, we examine how neural correlates of self-other resonance relate to prosocial decision-making. Subjects performed two tasks while undergoing fMRI: observation of a human hand pierced by a needle, and observation and imitation of emotional facial expressions. Outside the scanner, subjects played the Dictator Game with players of low or high income (represented by neutral-expression headshots). Subjects' offers in the Dictator Game were correlated with activity in neural systems associated with self-other resonance and anticorrelated with activity in systems implicated in the control of pain, affect, and imitation. Functional connectivity between areas involved in self-other resonance and top-down control was negatively correlated with subjects' offers. This study suggests that the interaction between self-other resonance and top-down control processes are an important component of prosocial inclinations towards others, even when biological stimuli associated with self-other resonance are limited. These findings support a view of prosocial decision-making grounded in embodied cognition. © 2016 Wiley Periodicals, Inc.

Load-cell based characterization system for a "Violin-Mode" shadow-sensor in advanced LIGO suspensions

NASA Astrophysics Data System (ADS)

Lockerbie, N. A.; Tokmakov, K. V.

2016-07-01

The background to this work was a prototype shadow sensor, which was designed for retro-fitting to an advanced LIGO (Laser Interferometer Gravitational wave Observatory) test-mass/mirror suspension, in which 40 kg test-mass/mirrors are each suspended by four approximately 600 mm long by 0.4 mm diameter fused-silica suspension fibres. The shadow sensor comprised a LED source of Near InfraRed (NIR) radiation and a rectangular silicon photodiode detector, which, together, were to bracket the fibre under test. The aim was to detect transverse Violin-Mode resonances in the suspension fibres. Part of the testing procedure involved tensioning a silica fibre sample and translating it transversely through the illuminating NIR beam, so as to measure the DC responsivity of the detection system to fibre displacement. However, an equally important part of the procedure, reported here, was to keep the fibre under test stationary within the beam, whilst trying to detect low-level AC Violin-Mode resonances excited on the fibre, in order to confirm the primary function of the sensor. Therefore, a tensioning system, incorporating a load-cell readout, was built into the test fibre's holder. The fibre then was excited by a signal generator, audio power amplifier, and distant loudspeaker, and clear resonances were detected. A theory for the expected fundamental resonant frequency as a function of fibre tension was developed and is reported here, and this theory was found to match closely with the detected resonant frequencies as they varied with tension. Consequently, the resonances seen were identified as being proper Violin-Mode fundamental resonances of the fibre, and the operation of the Violin-Mode detection system was validated.

Load-cell based characterization system for a "Violin-Mode" shadow-sensor in advanced LIGO suspensions.

PubMed

Lockerbie, N A; Tokmakov, K V

2016-07-01

The background to this work was a prototype shadow sensor, which was designed for retro-fitting to an advanced LIGO (Laser Interferometer Gravitational wave Observatory) test-mass/mirror suspension, in which 40 kg test-mass/mirrors are each suspended by four approximately 600 mm long by 0.4 mm diameter fused-silica suspension fibres. The shadow sensor comprised a LED source of Near InfraRed (NIR) radiation and a rectangular silicon photodiode detector, which, together, were to bracket the fibre under test. The aim was to detect transverse Violin-Mode resonances in the suspension fibres. Part of the testing procedure involved tensioning a silica fibre sample and translating it transversely through the illuminating NIR beam, so as to measure the DC responsivity of the detection system to fibre displacement. However, an equally important part of the procedure, reported here, was to keep the fibre under test stationary within the beam, whilst trying to detect low-level AC Violin-Mode resonances excited on the fibre, in order to confirm the primary function of the sensor. Therefore, a tensioning system, incorporating a load-cell readout, was built into the test fibre's holder. The fibre then was excited by a signal generator, audio power amplifier, and distant loudspeaker, and clear resonances were detected. A theory for the expected fundamental resonant frequency as a function of fibre tension was developed and is reported here, and this theory was found to match closely with the detected resonant frequencies as they varied with tension. Consequently, the resonances seen were identified as being proper Violin-Mode fundamental resonances of the fibre, and the operation of the Violin-Mode detection system was validated.

Load-cell based characterization system for a “Violin-Mode” shadow-sensor in advanced LIGO suspensions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lockerbie, N. A.; Tokmakov, K. V.

The background to this work was a prototype shadow sensor, which was designed for retro-fitting to an advanced LIGO (Laser Interferometer Gravitational wave Observatory) test-mass/mirror suspension, in which 40 kg test-mass/mirrors are each suspended by four approximately 600 mm long by 0.4 mm diameter fused-silica suspension fibres. The shadow sensor comprised a LED source of Near InfraRed (NIR) radiation and a rectangular silicon photodiode detector, which, together, were to bracket the fibre under test. The aim was to detect transverse Violin-Mode resonances in the suspension fibres. Part of the testing procedure involved tensioning a silica fibre sample and translating itmore » transversely through the illuminating NIR beam, so as to measure the DC responsivity of the detection system to fibre displacement. However, an equally important part of the procedure, reported here, was to keep the fibre under test stationary within the beam, whilst trying to detect low-level AC Violin-Mode resonances excited on the fibre, in order to confirm the primary function of the sensor. Therefore, a tensioning system, incorporating a load-cell readout, was built into the test fibre’s holder. The fibre then was excited by a signal generator, audio power amplifier, and distant loudspeaker, and clear resonances were detected. A theory for the expected fundamental resonant frequency as a function of fibre tension was developed and is reported here, and this theory was found to match closely with the detected resonant frequencies as they varied with tension. Consequently, the resonances seen were identified as being proper Violin-Mode fundamental resonances of the fibre, and the operation of the Violin-Mode detection system was validated.« less

Experimental demonstration of two methods for controlling the group delay in a system with photonic-crystal resonators coupled to a waveguide.

PubMed

Huo, Yijie; Sandhu, Sunil; Pan, Jun; Stuhrmann, Norbert; Povinelli, Michelle L; Kahn, Joseph M; Harris, James S; Fejer, Martin M; Fan, Shanhui

2011-04-15

We measure the group delay in an on-chip photonic-crystal device with two resonators side coupled to a waveguide. We demonstrate that such a group delay can be controlled by tuning either the propagation phase of the waveguide or the frequency of the resonators.

Analytical model for atomic resonant attosecond transient absorption

NASA Astrophysics Data System (ADS)

Cariker, C.; Kjellson, T.; Lindroth, E.; Argenti, L.

2017-04-01

Recent advancements in ultrafast laser technology have made it possible to probe electron dynamics in highly excited atomic states that autoionize on a femtosecond timescale, thus giving insight into the dynamics of Auger decay and its interference with the continuum. These experiments provide a stringent test for time-resolved analytical models of autoionization. Here we present a finite-pulse, multi-photon perturbative model which is used in conjunction with ab-initio structure calculations to predict the attosecond transient absorption spectrum (ATAS) of an atom above the ionization threshold. We apply this model to compute the ATAS of argon in the vicinity of the 3s-1 4 p resonance as a function of the time delay between an extreme ultraviolet (XUV) and an infrared (IR) pulse, as well as of the angle between their polarization. We show that by modulating the parameters of the IR pulse it is possible to control the dipolar coupling between neighboring states and hence the lineshape of the 3s-1 4 p resonance. NSF Grant No. 1607588.

Catheter-based flexible microcoil RF detectors for internal magnetic resonance imaging

NASA Astrophysics Data System (ADS)

Ahmad, M. M.; Syms, R. R. A.; Young, I. R.; Mathew, B.; Casperz, W.; Taylor-Robinson, S. D.; Wadsworth, C. A.; Gedroyc, W. M. W.

2009-07-01

Flexible catheter probes for magnetic resonance imaging (MRI) of the bile duct are demonstrated. The probes consist of a cytology brush modified to accept a resonant RF detector based on a spiral microcoil and hybrid integrated capacitors, and are designed for insertion into the duct via a non-magnetic endoscope during endoscopic retrograde cholangiopancreatography (ERCP). The coil must be narrow enough (<3 mm) to pass through the biopsy channel of the endoscope and sufficiently flexible to turn through 90° to enter the duct. Coils are fabricated as multi-turn electroplated conductors on a flexible base, and two designs formed on SU-8 and polyimide substrates are compared. It is shown that careful control of thermal load is used to obtain useable mechanical properties from SU-8, and that polyimide/SU-8 composites offer improved mechanical reliability. Good electrical performance is demonstrated and sub-millimetre resolution is obtained in 1H MRI experiments at 1.5 T magnetic field strength using test phantoms and in vitro liver tissue.

Morphological hippocampal markers for automated detection of Alzheimer's disease and mild cognitive impairment converters in magnetic resonance images.

PubMed

Ferrarini, Luca; Frisoni, Giovanni B; Pievani, Michela; Reiber, Johan H C; Ganzola, Rossana; Milles, Julien

2009-01-01

In this study, we investigated the use of hippocampal shape-based markers for automatic detection of Alzheimer's disease (AD) and mild cognitive impairment converters (MCI-c). Three-dimensional T1-weighted magnetic resonance images of 50 AD subjects, 50 age-matched controls, 15 MCI-c, and 15 MCI-non-converters (MCI-nc) were taken. Manual delineations of both hippocampi were obtained from normalized images. Fully automatic shape modeling was used to generate comparable meshes for both structures. Repeated permutation tests, run over a randomly sub-sampled training set (25 controls and 25 ADs), highlighted shape-based markers, mostly located in the CA1 sector, which consistently discriminated ADs and controls. Support vector machines (SVMs) were trained, using markers from either one or both hippocampi, to automatically classify control and AD subjects. Leave-1-out cross-validations over the remaining 25 ADs and 25 controls resulted in an optimal accuracy of 90% (sensitivity 92%), for markers in the left hippocampus. The same morphological markers were used to train SVMs for MCI-c versus MCI-nc classification: markers in the right hippocampus reached an accuracy (and sensitivity) of 80%. Due to the pattern recognition framework, our results statistically represent the expected performances of clinical set-ups, and compare favorably to analyses based on hippocampal volumes.

Mitigation of Subsynchronous Resonance with Fractional-order PI based UPFC controller

NASA Astrophysics Data System (ADS)

Raju, D. Koteswara; Umre, Bhimrao S.; Junghare, Anjali S.; Babu, B. Chitti

2017-02-01

Due to incorporation of series capacitor compensation in transmission line for stability improvement, subsynchronous oscillations are generated at turbine-generator shaft. These oscillations can damage the shaft system if these are not well suppressed. In order to damp out these oscillations, usually power system network should have sufficient damping and the increase of network damping is obtained by the injection of subsynchronous component of voltage and current into the line, which are extracted from the measured signal of the system. However, the effectiveness of damp out of these subsynchronous oscillations is possibly by incorporating UPFC in the transmission line network is of high interest and it should be further investigated. This research article proposes the mitigation of subsynchronous resonance (SSR) using fractional-order PI (FOPI) based unified power flow controller (UPFC). The robustness of the proposed controller is tested for 25%, 55% and 70% series compensation with a symmetrical fault (L-L-L fault). Further, Eigenvalue analysis and Fast Fourier Transform (FFT) analysis against operating point variations and uncertainties in the system are also examined. The IEEE first benchmark model is adopted for this study and the superiority of the FOPI based UPFC controller over PI based UPFC controller is discussed by comparing the results with various performance indices.

Microplasma generating array

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hopwood, Jeffrey A.; Wu, Chen; Hoskinson, Alan R.

A microplasma generator includes first and second conductive resonators disposed on a first surface of a dielectric substrate. The first and second conductive resonators are arranged in line with one another with a gap defined between a first end of each resonator. A ground plane is disposed on a second surface of the dielectric substrate and a second end of each of the first and second resonators is coupled to the ground plane. A power input connector is coupled to the first resonator at a first predetermined distance from the second end chosen as a function of the impedance ofmore » the first conductive resonator. A microplasma generating array includes a number of resonators in a dielectric material substrate with one end of each resonator coupled to ground. A micro-plasma is generated at the non-grounded end of each resonator. The substrate includes a ground electrode and the microplasmas are generated between the non-grounded end of the resonator and the ground electrode. The coupling of each resonator to ground may be made through controlled switches in order to turn each resonator off or on and therefore control where and when a microplasma will be created in the array.« less

Correlation between blink reflex abnormalities and magnetic resonance imaging findings in patients with multiple sclerosis.

PubMed

Degirmenci, Eylem; Erdogan, Cagdas; Bir, Levent Sinan

2013-09-01

This study investigates the correlation between brain magnetic resonance imaging findings and blink reflex abnormalities in patients with relapsing remitting multiple sclerosis. Twenty-six patients and 17 healthy subjects were included in this study. Blink reflex test (BRT) results were obtained using right and left stimulations; thus, 52 BRT results were recorded for the patient group, and 34 BRT results were recorded for the control group. The magnetic resonance imaging (MRI) findings were classified based on the existence of brainstem lesions (hyperintense lesion on T2 weighted (W) and fast fluid-attenuated inversion recovery MRI or contrast-enhancing lesion on T1W MRI). Correlation analysis was performed for the BRT and MRI findings. The percentage of individuals with abnormal BRT results (including R1 latency, ipsilateral R2 latency, and contralateral R2 latency) was significantly higher in the patient group as compared to the control group (p values: 0.015, 0.001, and 0.002, respectively). Correlation analysis revealed significant correlations between contralateral R2 latency abnormalities and brainstem lesions (p value: 0.011). Our results showed significant correlation correlations between contralateral R2 latency abnormalities and brainstem lesions and these results may be explained the effects of multiple demyelinating lesions of the brain stem of patients with relapsing remitting multiple sclerosis.

Classification of sodium MRI data of cartilage using machine learning.

PubMed

Madelin, Guillaume; Poidevin, Frederick; Makrymallis, Antonios; Regatte, Ravinder R

2015-11-01

To assess the possible utility of machine learning for classifying subjects with and subjects without osteoarthritis using sodium magnetic resonance imaging data. Theory: Support vector machine, k-nearest neighbors, naïve Bayes, discriminant analysis, linear regression, logistic regression, neural networks, decision tree, and tree bagging were tested. Sodium magnetic resonance imaging with and without fluid suppression by inversion recovery was acquired on the knee cartilage of 19 controls and 28 osteoarthritis patients. Sodium concentrations were measured in regions of interests in the knee for both acquisitions. Mean (MEAN) and standard deviation (STD) of these concentrations were measured in each regions of interest, and the minimum, maximum, and mean of these two measurements were calculated over all regions of interests for each subject. The resulting 12 variables per subject were used as predictors for classification. Either Min [STD] alone, or in combination with Mean [MEAN] or Min [MEAN], all from fluid suppressed data, were the best predictors with an accuracy >74%, mainly with linear logistic regression and linear support vector machine. Other good classifiers include discriminant analysis, linear regression, and naïve Bayes. Machine learning is a promising technique for classifying osteoarthritis patients and controls from sodium magnetic resonance imaging data. © 2014 Wiley Periodicals, Inc.

Dental materials and magnetic resonance imaging.

PubMed

Hubálková, Hana; Hora, Karel; Seidl, Zdenek; Krásenský, Jan

2002-09-01

The objective of this investigation was to evaluate the reaction of selected dental materials in the magnetic field of a magnetic resonance imaging device to determine a possible health risk. The following dental materials were tested in vitro during magnetic resonance imaging: 15 dental alloys, four dental implants, one surgical splint and two wires for fixation of maxillofacial fractures. Possible artefacts (corresponding with magnetic properties), heating and force effects were tested. Results concerning movement and heating were in agreement with the literature. The artefacts seen were significant: for the surgical splint, a spherical artefact with a diameter of 55 mm; for the wires, up to 22 mm; and for the dental blade implant, an artefact of 28 x 20 mm. The results of our tests of selected dental appliances indicate that their presence in the human organism is safe for patients undergoing magnetic resonance imaging procedures. The presence of artefacts can substantially influence the magnetic resonance imaging results.

Oven controlled N++ [1 0 0] length-extensional mode silicon resonator with frequency stability of 1 ppm over industrial temperature range

NASA Astrophysics Data System (ADS)

You, Weilong; Pei, Binbin; Sun, Ke; Zhang, Lei; Yang, Heng; Li, Xinxin

2017-10-01

This paper presents an oven controlled N++ [1 0 0] length-extensional mode silicon resonator, with a lookup-table based control algorithm. The temperature coefficient of resonant frequency (TCF) of the N++ doped resonator is nonlinear, and there is a turnover temperature point at which the TCF is equal to zero. The resonator is maintained at the turnover point by Joule heating; this temperature is a little higher than the upper limit of the industrial temperature range. It is demonstrated that the control algorithm based on the thermoresistor on the substrate and the lookup table for heating voltage versus chip temperature is sufficiently accurate to achieve a frequency stability of  ±0.5 ppm over the industrial temperature range. Because only two leads are required for electrical heating and piezoresistive sensing, the power required for heating of this resonator can be potentially lower than that of the oscillators with closed-loop oven control algorithm. It is also shown that the phase noise can be suppressed at the turnover temperature because of the very low value of the TCF, which justifies the usage of the heating voltage as the excitation voltage of the Wheatstone half-bridge.

A microwave resonance dew-point hygrometer

NASA Astrophysics Data System (ADS)

Underwood, R. J.; Cuccaro, R.; Bell, S.; Gavioso, R. M.; Madonna Ripa, D.; Stevens, M.; de Podesta, M.

2012-08-01

We report the first measurements of a quasi-spherical microwave resonator used as a dew-point hygrometer. In conventional dew-point hygrometers, the condensation of water from humid gas flowing over a mirror is detected optically, and the mirror surface is then temperature-controlled to yield a stable condensed layer. In our experiments we flowed moist air from a humidity generator through a quasi-spherical resonator and detected the onset of condensation by measuring the frequency ratio of selected microwave modes. We verified the basic operation of the device over the dew-point range 9.5-13.5 °C by comparison with calibrated chilled-mirror hygrometers. These tests indicate that the microwave method may allow a quantitative estimation of the volume and thickness of the water layer which is condensed on the inner surface of the resonator. The experiments reported here are preliminary due to the limited time available for the work, but show the potential of the method for detecting not only water but a variety of other liquid or solid condensates. The robust all-metal construction should make the device appropriate for use in industrial applications over a wide range of temperatures and pressures.

Design and performance test of a MEMS vibratory gyroscope with a novel AGC force rebalance control

NASA Astrophysics Data System (ADS)

Sung, Woon-Tahk; Sung, Sangkyung; Lee, Jang Gyu; Kang, Taesam

2007-10-01

In this paper, the development and performance test results of a laterally oscillating MEMS gyroscope using a novel force rebalance control strategy are presented. The micromachined structure and electrodes are fabricated using the deep reactive ion etching (DRIE) and anodic wafer bonding process. The high quality factor required for the resonance-based sensor is achieved using a vacuum-sealed device package. A systematic design approach of the force rebalance control is applied via a modified automatic gain control (AGC) method. The rebalance control design takes advantages of a novel AGC loop modification, which allows the approximation of the system's dynamics into a simple linear form. Using the proposed modification of AGC and the rebalance strategy that maintains a biased oscillation, a number of performance improvements including bandwidth extension and widened operating range were observed to be achieved. Finally, the experimental results of the gyroscope's practical application verify the feasibility and performance of the developed sensor.

The anode power supply for the ECRH system on the J-TEXT tokamak

NASA Astrophysics Data System (ADS)

Donghui, XIA; Fangtai, CUI; Changhai, LIU; Zhenxiong, YU; Yikun, JIN; Zhijiang, WANG; J-TEXT, Team1

2018-01-01

The electron cyclotron resonance heating (ECRH) system with a 60 GHz/200 kW/0.5 s gyrotron donated by the Culham Science Center is being developed on the J-TEXT tokamak for plasma heating, current drive and MHD studies. Simultaneously, an anode power supply (APS) has been rebuilt and tested for the output power control of the gyrotron, of which the input voltage is derived from an 80 kV negative cathode power supply. The control strategy by controlling the grid voltage of the tetrode TH5186 is applied to obtain an accurate anode climbing voltage, of which the output voltage can be obtained from 0-30 kV with respect to the cathode power supply. The characteristics of the APS, including control, protection, modulation, and output waveform, were tested with a 100 kV/60 A negative cathode power supply, a dummy load and the ECRH control system. The results indicate that the APS can meet the requirements of the ECRH system on J-TEXT.

Resonant Column Tests and Nonlinear Elasticity in Simulated Rocks

NASA Astrophysics Data System (ADS)

Sebastian, Resmi; Sitharam, T. G.

2018-01-01

Rocks are generally regarded as linearly elastic even though the manifestations of nonlinearity are prominent. The variations of elastic constants with varying strain levels and stress conditions, disagreement between static and dynamic moduli, etc., are some of the examples of nonlinear elasticity in rocks. The grain-to-grain contact, presence of pores and joints along with other compliant features induce the nonlinear behavior in rocks. The nonlinear elastic behavior of rocks is demonstrated through resonant column tests and numerical simulations in this paper. Resonant column tests on intact and jointed gypsum samples across varying strain levels have been performed in laboratory and using numerical simulations. The paper shows the application of resonant column apparatus to obtain the wave velocities of stiff samples at various strain levels under long wavelength condition, after performing checks and incorporating corrections to the obtained resonant frequencies. The numerical simulation and validation of the resonant column tests using distinct element method are presented. The stiffness reductions of testing samples under torsional and flexural vibrations with increasing strain levels have been analyzed. The nonlinear elastic behavior of rocks is reflected in the results, which is enhanced by the presence of joints. The significance of joint orientation and influence of joint spacing during wave propagation have also been assessed and presented using the numerical simulations. It has been found that rock joints also exhibit nonlinear behavior within the elastic limit.

Comparative histomorphometry and resonance frequency analysis of implants with moderately rough surfaces in a loaded animal model.

PubMed

Al-Nawas, B; Groetz, K A; Goetz, H; Duschner, H; Wagner, W

2008-01-01

Test of favourable conditions for osseointegration with respect to optimum bone-implant contact (BIC) in a loaded animal model. The varied parameters were surface roughness and surface topography of commercially available dental implants. Thirty-two implants of six types of macro and microstructure were included in the study (total 196). The different types were: minimally rough control: Branemark machined Mk III; oxidized surface: TiUnite MkIII and MkIV; ZL Ticer; blasted and etched surface: Straumann SLA; rough control: titanium plasma sprayed (TPS). Sixteen beagle dogs were implanted with the whole set of the above implants. After a healing period of 8 weeks, implants were loaded for 3 months. For the evaluation of the BIC areas, adequately sectioned biopsies were visualized by subsurface scans with confocal laser scanning microscopy (CLSM). The primary statistical analysis testing BIC of the moderately rough implants (mean 56.1+/-13.0%) vs. the minimally rough and the rough controls (mean 53.9+/-11.2%) does not reveal a significant difference (P=0.57). Mean values of 50-70% BIC were found for all implant types. Moderately rough oxidized implants show a median BIC, which is 8% higher than their minimally rough turned counterpart. The intraindividual difference between the TPS and the blasted and etched counterparts revealed no significant difference. The turned and the oxidized implants show median values of the resonance frequency [implant stability quotients (ISQ)] over 60; the nonself-tapping blasted and etched and TPS implants show median values below 60. In conclusion, the benefit of rough surfaces relative to minimally rough ones in this loaded animal model was confirmed histologically. The comparison of different surface treatment modalities revealed no significant differences between the modern moderately rough surfaces. Resonance frequency analysis seems to be influenced in a major part by the transducer used, thus prohibiting the comparison of different implant systems.

Experience of diffusion tensor imaging and 1H spectroscopy for outcome prediction in severe traumatic brain injury: Preliminary results.

PubMed

Tollard, Eléonore; Galanaud, Damien; Perlbarg, Vincent; Sanchez-Pena, Paola; Le Fur, Yann; Abdennour, Lamine; Cozzone, Patrick; Lehericy, Stéphane; Chiras, Jacques; Puybasset, Louis

2009-04-01

The objective of the study is to test whether multimodal magnetic resonance imaging can provide a reliable outcome prediction of the clinical status, focusing on consciousness at 1 year after severe traumatic brain injury (TBI). Single center prospective cohort with consecutive inclusions. Critical Care Neurosurgical Unit of a university hospital. Forty-three TBI patients not responding to simple orders after sedation cessation and 15 healthy controls. A multimodal magnetic resonance imaging combining morphologic sequences, diffusion tensor imaging (DTI), and H proton magnetic resonance spectroscopy (MRS) was performed 24 +/- 11 days after severe TBI. The ability of DTI and MRS to predict 1-year outcome was assessed by linear discriminant analysis (LDA). Robustness of the classification was tested using a bootstrap procedure. Fractional anisotropy (FA) was computed as the mean of values at discrete brain sites in the infratentorial and supratentorial regions. The N-acetyl aspartate/creatine (NAA/Cr) ratio was measured in the thalamus, lenticular nucleus, insular cortex, occipital periventricular white matter, and pons. After 1 year, 19 (44%) patients had unfavorable outcomes (death, persistent vegetative state, or minimally conscious state) and 24 (56%) favorable outcomes (normal consciousness with or without functional impairments). Analysis of variance was performed to compare FA and NAA/Cr in the two outcome groups and controls. FA and MRS findings showed highly significant differences between the outcome groups, with significant variables by LDA being supratentorial FA, NAA/Cr (pons), NAA/Cr (thalamus), NAA/Cr (insula), and infratentorial FA. LDA of combined FA and MRS data clearly separated the unfavorable outcome, favorable outcome, and control groups, with no overlap. Unfavorable outcome was predicted with up to 86% sensitivity and 97% specificity; these values were better than those obtained with DTI or MRS alone. FA and NAA/Cr hold potential as quantitative outcome-prediction tools at the subacute phase of TBI.

Can Internal Conversion BE Controlled by Mode-Specific Vibrational Excitation in Polyatomic Molecules

NASA Astrophysics Data System (ADS)

Portnov, Alexander; Epshtein, Michael; Bar, Ilana

2017-06-01

Nonadiabatic processes, dominated by dynamic passage of reactive fluxes through conical intersections (CIs) are considered to be appealing means for manipulating reaction paths. One approach that is considered to be effective in controlling the course of dissociation processes is the selective excitation of vibrational modes containing a considerable component of motion. Here, we have chosen to study the predissociation of the model test molecule, methylamine and its deuterated isotopologues, excited to well-characterized quantum states on the first excited electronic state, S_{1}, by following the N-H(D) bond fission dynamics through sensitive H(D) photofragment probing. The branching ratios between slow and fast H(D) photofragments, the internal energies of their counter radical photofragments and the anisotropy parameters for fast H photofragments, confirm correlated anomalies for predissociation initiated from specific rovibronic states, reflecting the existence of a dynamic resonance in each molecule. This resonance strongly depends on the energy of the initially excited rovibronic states, the evolving vibrational mode on the repulsive S_{1} part during N-H(D) bond elongation, and the manipulated passage through the CI that leads to radicals excited with C-N-H(D) bending and preferential perpendicular bond breaking, relative to the photolyzing laser polarization, in molecules containing the NH_{2} group. The indicated resonance plays an important role in the bifurcation dynamics at the CI and can be foreseen to exist in other photoinitiated processes and to control their outcome.

Resonant AC power system proof-of-concept test program

NASA Technical Reports Server (NTRS)

Wappes, Loran J.

1986-01-01

Proof-of-concept testing was performed on a 20-kHz, resonant power system breadboard from 1981 through 1985. The testing began with the evaluation of a single, 1.0-kW resonant inverter and progressed to the testing of breadboard systems with higher power levels and more capability. The final breadboard configuration tested was a 25.0-kW breadboard with six inverters providing power to three user-interface modules over a 50-meter, 20-kHz bus. The breadboard demonstrated the ability to synchronize multiple resonant inverters to power a common bus. Single-phase and three-phase 20-kHz power distribution was demonstrated. Simple conversion of 20-kHz to dc and variable-frequency ac was demonstrated as was bidirectional power flow between 20-kHz and dc. Steady state measurements of efficiency, power-factor tolerance, and conducted emissions and conducted susceptibility were made. In addition, transient responses were recorded for such conditions as start up, shut down, load changes. The results showed the 20-kHz resonant system to be a desirable technology for a spacecraft power management and distribution system with multiple users and a utility-type bus.

Flutist produces four resonances with a single bottle

NASA Astrophysics Data System (ADS)

Ruiz, Michael J.; Boysen, Erika

2017-03-01

In a dramatic physics demonstration, a professional flutist produces four resonances with a 12 ounce Boylan soda bottle solely through her breath control. The 22 cm bottle acts like a Helmholtz resonator for the lowest pitch. The three higher pitches fall near the 3rd, 5th, and 7th harmonics for a 22 cm closed pipe. A video of this remarkable feat is provided (Ruiz 2016 YouTube: Four Resonances with a 12-ounce Soda Bottle (https://youtu.be/ibtVrp2NF_k)). The video also reveals that a flutist can bend resonance pitches by as much as 10% through control of air speed.

The positive effects of high-frequency right dorsolateral prefrontal cortex repetitive transcranial magnetic stimulation on memory, correlated with increases in brain metabolites detected by proton magnetic resonance spectroscopy in recently detoxified alcohol-dependent patients.

PubMed

Qiao, Jun; Jin, Guixing; Lei, Licun; Wang, Lan; Du, Yaqiang; Wang, Xueyi

2016-01-01

To explore the effect of right dorsolateral prefrontal cortex (DLPFC) repetitive transcranial magnetic stimulation (rTMS) on memory, and its correlation with levels of hippocampal brain metabolites detected by proton magnetic resonance spectroscopy ( 1 H-MRS) in recently detoxified alcohol-dependent patients. In this randomized, double-blind sham-controlled trial, alcohol-dependent patients were enrolled and randomized into two groups: the experimental group (rTMS, 10 Hz, on right DLPFC, 20 sessions) and the control group (sham stimulation). Memory function was assessed using Hopkins Verbal Learning Test-Revised (HVLT-R) and Brief Visuospatial Memory Test-Revised (BVMT-R) before and after treatment. 1 H-MRS was used to detect the levels of N -acetyl aspartic acid (NAA), choline (Cho), and creatine (Cr) in bilateral hippocampi before and after treatment. Thirty-eight patients (18 in the experimental group and 20 in the control group) were included in the analyses. The experimental group showed significantly greater changes in HVLT-R, BVMT-R, NAA/Cr, and Cho/Cr after rTMS from baseline than the control group. The percentage change in BVMT-R and HVLT-R correlated with the percentage change in NAA/Cr and Cho/Cr in the right brain. High-frequency right DLPFC rTMS was associated with improvement in memory dysfunction, which is correlated with levels of hippocampal brain metabolites detected by 1 H-MRS in recently detoxified alcohol-dependent patients.

A Fourier analysis for a fast simulation algorithm. [for switching converters

NASA Technical Reports Server (NTRS)

King, Roger J.

1988-01-01

This paper presents a derivation of compact expressions for the Fourier series analysis of the steady-state solution of a typical switching converter. The modeling procedure for the simulation and the steady-state solution is described, and some desirable traits for its matrix exponential subroutine are discussed. The Fourier analysis algorithm was tested on a phase-controlled parallel-loaded resonant converter, providing an experimental confirmation.

Dynamics Control Approaches to Improve Vibratory Environment of the Helicopter Aircrew

NASA Astrophysics Data System (ADS)

Wickramasinghe, Viresh Kanchana

Although helicopter has become a versatile mode of aerial transportation, high vibration levels leads to poor ride quality for its passengers and aircrew. Undesired vibration transmitted through the helicopter seats have been known to cause fatigue and discomfort to the aircrew in the short-term as well as neck strain and back pain injuries due to long-term exposure. This research study investigated the use of novel active as well as passive methodologies integrated in helicopter seats to mitigate the aircrew exposure to high vibration levels. Due to significantly less certification effort required to modify the helicopter seat structure, application of novel technologies to the seat is more practical compared to flight critical components such as the main rotor to reduce aircrew vibration. In particular, this research effort developed a novel adaptive seat mount approach based on active vibration control technology. This novel design that incorporated two stacked piezoelectric actuators as active struts increases the bending stiffness to avoid the low frequency resonance while generating forces to counteract higher harmonic vibration peaks. A real-time controller implemented using a feed-forward algorithm based on adaptive notches counteracted the forced vibration peaks while a robust feedback control algorithm suppressed the resonance modes. The effectiveness of the adaptive seat mount system was demonstrated through extensive closed-loop control tests on a full-scale helicopter seat using representative helicopter floor vibration profiles. Test results concluded that the proposed adaptive seat mount approach based on active control technology is a viable solution for the helicopter seat vibration control application. In addition, a unique flight test using a Bell-412 helicopter demonstrated that the aircrew is exposed to high levels of vibration during flight and that the whole body vibration spectrum varied substantially depending on operating conditions as well as the aircrew configurations. This investigation also demonstrated the suitability of integrating novel energy absorbing cushion materials to the seat as a low cost solution to improve aircrew vibration suppression. Therefore, it was recommended to pursue certification of novel seat cushion materials as a near-term solution to mitigate undesirable occupational health hazards in helicopter aircrew due to vibration exposure.

Near-infrared resonance-mediated chirp control of a coherently generated broadband deep-ultraviolet spectrum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rybak, Leonid; Chuntonov, Lev; Gandman, Andrey

2011-09-15

We investigate the use of shaped near-infrared (NIR) femtosecond pulses to control the generation of coherent broadband deep-ultraviolet (DUV) radiation in an atomic resonance-mediated (2+1) three-photon excitation to a broad far-from-resonance continuum. Previously, we have shown control over the total emitted DUV yield. Here, we experimentally demonstrate phase control over the spectral characteristics (central frequency and bandwidth) of the emitted broadband DUV radiation. It is achieved by tuning the linear chirp applied to the exciting NIR femtosecond pulse. The study is conducted with Na vapor.

Center Frequency Stabilization in Planar Dual-Mode Resonators during Mode-Splitting Control

NASA Astrophysics Data System (ADS)

Naji, Adham; Soliman, Mina H.

2017-03-01

Shape symmetry in dual-mode planar electromagnetic resonators results in their ability to host two degenerate resonant modes. As the designer enforces a controllable break in the symmetry, the degeneracy is removed and the two modes couple, exchanging energy and elevating the resonator into its desirable second-order resonance operation. The amount of coupling is controlled by the degree of asymmetry introduced. However, this mode coupling (or splitting) usually comes at a price. The centre frequency of the perturbed resonator is inadvertently drifted from its original value prior to coupling. Maintaining centre frequency stability during mode splitting is a nontrivial geometric design problem. In this paper, we analyse the problem and propose a novel method to compensate for this frequency drift, based on field analysis and perturbation theory, and we validate the solution through a practical design example and measurements. The analytical method used works accurately within the perturbational limit. It may also be used as a starting point for further numerical optimization algorithms, reducing the required computational time during design, when larger perturbations are made to the resonator. In addition to enabling the novel design example presented, it is hoped that the findings will inspire akin designs for other resonator shapes, in different disciplines and applications.

Transmission loss of double wall panels containing Helmholtz resonators

NASA Technical Reports Server (NTRS)

Prydz, R. A.; Kuntz, H. L.; Morrow, D. L.; Wirt, L. S.

1988-01-01

Data and an analysis are presented on the use of Helholtz resonators in double wall panels (i.e., aircraft sidewalls). Several wall materials and resonator configurations were tested, and the resonators were found to substantially increase the transmission loss of the double wall system at the tuning frequency.

Transmission loss of double wall panels containing Helmholtz resonators

NASA Astrophysics Data System (ADS)

Prydz, R. A.; Kuntz, H. L.; Morrow, D. L.; Wirt, L. S.

Data and an analysis are presented on the use of Helholtz resonators in double wall panels (i.e., aircraft sidewalls). Several wall materials and resonator configurations were tested, and the resonators were found to substantially increase the transmission loss of the double wall system at the tuning frequency.

Clinical outcomes after magnetic resonance angiography (MRA) versus computed tomographic angiography (CTA) for pulmonary embolism evaluation.

PubMed

Repplinger, Michael D; Nagle, Scott K; Harringa, John B; Broman, Aimee T; Lindholm, Christopher R; François, Christopher J; Grist, Thomas M; Reeder, Scott B; Schiebler, Mark L

2018-05-10

To compare patient outcomes following magnetic resonance angiography (MRA) versus computed tomographic angiography (CTA) ordered for suspected pulmonary embolism (PE). In this IRB-approved, single-center, retrospective, case-control study, we reviewed the medical records of all patients evaluated for PE with MRA during a 5-year period along with age- and sex-matched controls evaluated with CTA. Only the first instance of PE evaluation during the study period was included. After application of our exclusion criteria to both study arms, the analysis included 1173 subjects. The primary endpoint was major adverse PE-related event (MAPE), which we defined as major bleeding, venous thromboembolism, or death during the 6 months following the index imaging test (MRA or CTA), obtained through medical record review. Logistic regression, chi-square test for independence, and Fisher's exact test were used with a p < 0.05 threshold. The overall 6-month MAPE rate following MRA (5.4%) was lower than following CTA (13.6%, p < 0.01). Amongst outpatients, the MAPE rate was lower for MRA (3.7%) than for CTA (8.0%, p = 0.01). Accounting for age, sex, referral source, BMI, and Wells' score, patients were less likely to suffer MAPE than those who underwent CTA, with an odds ratio of 0.44 [0.24, 0.80]. Technical success rate did not differ significantly between MRA (92.6%) and CTA (90.5%) groups (p = 0.41). Within the inherent limitations of a retrospective case-controlled analysis, we observed that the rate of MAPE was lower (more favorable) for patients following pulmonary MRA for the primary evaluation of suspected PE than following CTA.

Multi-task functional MRI in multiple sclerosis patients without clinical disability.

PubMed

Colorado, René A; Shukla, Karan; Zhou, Yuxiang; Wolinsky, Jerry S; Narayana, Ponnada A

2012-01-02

While the majority of individuals with multiple sclerosis (MS) develop significant clinical disability, a subset experiences a disease course with minimal impairment even in the presence of significant apparent tissue damage on magnetic resonance imaging (MRI). Functional magnetic resonance imaging (fMRI) in MS patients with low disability suggests that increased use of the cognitive control system may limit the clinical manifestation of the disease. The current fMRI studies tested the hypothesis that nondisabled MS patients show increased recruitment of cognitive control regions while performing sensory, motor and cognitive tasks. Twenty two patients with relapsing-remitting MS and an Expanded Disability Status Scale (EDSS) score of ≤1.5 and 23 matched healthy controls were recruited. Subjects underwent fMRI while observing flashing checkerboards, performing right or left hand movements, or executing the 2-back working memory task. Compared to control subjects, patients demonstrated increased activation of the right dorsolateral prefrontal cortex and anterior cingulate cortex during the performance of the working memory task. This pattern of functional recruitment also was observed during the performance of non-dominant hand movements. These results support the mounting evidence of increased functional recruitment of cognitive control regions in the working memory system of MS patients with low disability and provide new evidence for the role of increased cognitive control recruitment in the motor system. Copyright © 2011 Elsevier Inc. All rights reserved.

Bi-Frequency Modulated Quasi-Resonant Converters: Theory and Applications

NASA Astrophysics Data System (ADS)

Zhang, Yuefeng

1995-01-01

To avoid the variable frequency operation of quasi -resonant converters, many soft-switching PWM converters have been proposed, all of them require an auxiliary switch, which will increase the cost and complexity of the power supply system. In this thesis, a new kind of technique for quasi -resonant converters has been proposed, which is called the bi-frequency modulation technique. By operating the quasi-resonant converters at two switching frequencies, this technique enables quasi-resonant converters to achieve the soft-switching, at fixed switching frequencies, without an auxiliary switch. The steady-state analysis of four commonly used quasi-resonant converters, namely, ZVS buck, ZCS buck, ZVS boost, and ZCS boost converter has been presented. Using the concepts of equivalent sources, equivalent sinks, and resonant tank, the large signal models of these four quasi -resonant converters were developed. Based on these models, the steady-state control characteristics of BFM ZVS buck, BFM ZCS buck, BFM ZVS boost, and BFM ZCS boost converter have been derived. The functional block and design consideration of the bi-frequency controller were presented, and one of the implementations of the bi-frequency controller was given. A complete design example has been presented. Both computer simulations and experimental results have verified that the bi-frequency modulated quasi-resonant converters can achieve soft-switching, at fixed switching frequencies, without an auxiliary switch. One of the application of bi-frequency modulation technique is for EMI reduction. The basic principle of using BFM technique for EMI reduction was introduced. Based on the spectral analysis, the EMI performances of the PWM, variable-frequency, and bi-frequency modulated control signals was evaluated, and the BFM control signals show the lowest EMI emission. The bi-frequency modulated technique has also been applied to the power factor correction. A BFM zero -current switching boost converter has been designed for the power factor correction, and the simulation results show that the power factor has been improved.

CFAVC scheme for high frequency series resonant inverter-fed domestic induction heating system

NASA Astrophysics Data System (ADS)

Nagarajan, Booma; Reddy Sathi, Rama

2016-01-01

This article presents the investigations on the constant frequency asymmetric voltage cancellation control in the AC-AC resonant converter-fed domestic induction heating system. Conventional fixed frequency control techniques used in the high frequency converters lead to non-zero voltage switching operation and reduced output power. The proposed control technique produces higher output power than the conventional fixed-frequency control strategies. In this control technique, zero-voltage-switching operation is maintained during different duty cycle operation for reduction in the switching losses. Complete analysis of the induction heating power supply system with asymmetric voltage cancellation control is discussed in this article. Simulation and experimental study on constant frequency asymmetric voltage cancellation (CFAVC)-controlled full bridge series resonant inverter is performed. Time domain simulation results for the open and closed loop of the system are obtained using MATLAB simulation tool. The simulation results prove the control of voltage and power in a wide range. PID controller-based closed loop control system achieves the voltage regulation of the proposed system for the step change in load. Hardware implementation of the system under CFAVC control is done using the embedded controller. The simulation and experimental results validate the performance of the CFAVC control technique for series resonant-based induction cooking system.

Impact of depth and location of the wells on vibrational resonance in a triple-well system

NASA Astrophysics Data System (ADS)

Chen, Zhijuan; Ning, Lijuan

2018-04-01

The effect of depth and location of a triple-well potential on vibrational resonance is investigated in a quintic oscillator driven by a low-frequency force and a high-frequency force. The values of low-frequency ω and amplitude g of the high-frequency force at which vibrational resonance occurs are derived both numerically and theoretically. It is found that: as ω varies, at most one resonance takes place and the response amplitude at resonance depends on the depth and the location of the potential wells. When g is altered, the depth and location of wells can control the number of resonances, resulting in two, three and four resonances. The system parameters can be adjusted by controlling the depth and position of the wells to achieve optimum vibrational resonance. Furthermore, the changes induced by these two quantities in the tristable system are found to be richer than those induced in bistable systems.

A theory for predicting boundary impedance and resonance frequencies of slotted-wall wind tunnels, including plenum effects

NASA Technical Reports Server (NTRS)

Barger, R. L.

1981-01-01

Wave-induced resonance associated with the geometry of wind-tunnel test sections can occur. A theory that uses acoustic impedance concepts to predict resonance modes in a two dimensional, slotted wall wind tunnel with a plenum chamber is described. The equation derived is consistent with known results for limiting conditions. The computed resonance modes compare well with appropriate experimental data. When the theory is applied to perforated wall test sections, it predicts the experimentally observed closely spaced modes that occur when the wavelength is not long compared with he plenum depth.

Control of Resonances and Optical Properties of Plasmonic-Patch Metamaterials

DTIC Science & Technology

2012-08-01

entitled "Control of resonances and optical properties of plasmonic-patch metamaterials", under Award No. FA2386-11-1-4707 The stated research goals...their photonic properties when nonlinear amplifying dye molecules are imbedded in the structures. We will particularly focus on three...metamaterial structures. 4. Measurement of plasmon resonance and florescence properties in the dye-doped metamaterials with and without the

Adaptive model-predictive controller for magnetic resonance guided focused ultrasound therapy.

PubMed

de Bever, Joshua; Todd, Nick; Payne, Allison; Christensen, Douglas A; Roemer, Robert B

2014-11-01

Minimising treatment time and protecting healthy tissues are conflicting goals that play major roles in making magnetic resonance image-guided focused ultrasound (MRgFUS) therapies clinically practical. We have developed and tested in vivo an adaptive model-predictive controller (AMPC) that reduces treatment time, ensures safety and efficacy, and provides flexibility in treatment set-up. The controller realises time savings by modelling the heated treatment cell's future temperatures and thermal dose accumulation in order to anticipate the optimal time to switch to the next cell. Selected tissues are safeguarded by a configurable temperature constraint. Simulations quantified the time savings realised by each controller feature as well as the trade-offs between competing safety and treatment time parameters. In vivo experiments in rabbit thighs established the controller's effectiveness and reliability. In all in vivo experiments the target thermal dose of at least 240 CEM43 was delivered everywhere in the treatment volume. The controller's temperature safety limit reliably activated and constrained all protected tissues to <9 CEM43. Simulations demonstrated the path independence of the controller, and that a path which successively proceeds to the hottest untreated neighbouring cell leads to significant time savings, e.g. when compared to a concentric spiral path. Use of the AMPC produced a compounding time-saving effect; reducing the treatment cells' heating times concurrently reduced heating of normal tissues, which eliminated cooling periods. Adaptive model-predictive control can automatically deliver safe, effective MRgFUS treatments while significantly reducing treatment times.

Non-linear resonant coupling of tsunami edge waves using stochastic earthquake source models

USGS Publications Warehouse

Geist, Eric L.

2016-01-01

Non-linear resonant coupling of edge waves can occur with tsunamis generated by large-magnitude subduction zone earthquakes. Earthquake rupture zones that straddle beneath the coastline of continental margins are particularly efficient at generating tsunami edge waves. Using a stochastic model for earthquake slip, it is shown that a wide range of edge-wave modes and wavenumbers can be excited, depending on the variability of slip. If two modes are present that satisfy resonance conditions, then a third mode can gradually increase in amplitude over time, even if the earthquake did not originally excite that edge-wave mode. These three edge waves form a resonant triad that can cause unexpected variations in tsunami amplitude long after the first arrival. An M ∼ 9, 1100 km-long continental subduction zone earthquake is considered as a test case. For the least-variable slip examined involving a Gaussian random variable, the dominant resonant triad includes a high-amplitude fundamental mode wave with wavenumber associated with the along-strike dimension of rupture. The two other waves that make up this triad include subharmonic waves, one of fundamental mode and the other of mode 2 or 3. For the most variable slip examined involving a Cauchy-distributed random variable, the dominant triads involve higher wavenumbers and modes because subevents, rather than the overall rupture dimension, control the excitation of edge waves. Calculation of the resonant period for energy transfer determines which cases resonant coupling may be instrumentally observed. For low-mode triads, the maximum transfer of energy occurs approximately 20–30 wave periods after the first arrival and thus may be observed prior to the tsunami coda being completely attenuated. Therefore, under certain circumstances the necessary ingredients for resonant coupling of tsunami edge waves exist, indicating that resonant triads may be observable and implicated in late, large-amplitude tsunami arrivals.

Multi-ion, multi-event test of ion cyclotron resonance heating

NASA Technical Reports Server (NTRS)

Persoon, Ann M.

1993-01-01

The multi-ion, multi-event study of ion cyclotron resonance heating has been funded to study ion energization through ion cyclotron resonance with low frequency broadband electromagnetic turbulence. The modeling algorithm for the ion cyclotron resonance heating (ICRH) of oxygen ions was presented in Crew et al. (1990). Crew and his co-authors developed a two-parameter representation of selected oxygen conic distributions and modelled the conic formation in terms of resonance heating. The first year of this study seeks to extend the work of Crew and his co-authors by testing the applicability of the ICRH mechanism to helium ion conic distributions, using data obtained from the Energetic Ion Composition Spectrometer and the Plasma Wave Instrument on Dynamics Explorer 1.

Control of critical coupling in a coiled coaxial cable resonator.

PubMed

Huang, Jie; Wei, Tao; Wang, Tao; Fan, Jun; Xiao, Hai

2014-05-01

This paper reports a coiled coaxial cable resonator fabricated by cutting a slot in a spring-like coiled coaxial cable to produce a periodic perturbation. Electromagnetic coupling between two neighboring slots was observed. By manipulating the number of slots, critical coupling of the coiled coaxial cable resonator can be well controlled. An ultrahigh signal-to-noise ratio (over 50 dB) at the resonant frequency band was experimentally achieved from a coiled coaxial cable resonator with 38 turns. A theoretic model is developed to understand the device physics. The proposed device can be potentially used as a high quality and flexibly designed band-stop filter or a sensor in structural health monitoring.

Note: A component-level frequency tunable isolator for vibration-sensitive chips using SMA beams.

PubMed

Zhang, Xiaoyong; Ding, Xin; Wu, Di; Qi, Junlei; Wang, Ruixin; Lu, Siwei; Yan, Xiaojun

2016-06-01

This note presents a component-level frequency tunable isolator for vibration-sensitive chips. The isolator employed 8 U-shaped shape memory alloy (SMA) beams to support an isolation island (used for mounting chips). Due to the temperature-induced Young's modulus variation of SMA, the system stiffness of the isolator can be controlled through heating the SMA beams. In such a way, the natural frequency of the isolator can be tuned. A prototype was fabricated to evaluate the concept. The test results show that the natural frequency of the isolator can be tuned in the range of 64 Hz-97 Hz by applying different heating strategies. Moreover, resonant vibration can be suppressed significantly (the transmissibility decreases about 65% near the resonant frequency) using a real-time tuning method.

Safety of MRI with metallic middle ear implants.

PubMed

Tohme, Souheil M; Karkas, Alexandre A; Romanos, Bassam H

2003-01-01

Investigation of the effects of magnetic resonance fields on commonly used metallic middle ear implants. Nine middle ear prostheses (seven containing stainless steel and two made of pure gold used as control) were tested in vitro and one stainless steel stapedectomy prosthesis was tested on a cadaveric temporal bone. Each metallic prosthesis was placed in an empty Petri dish and introduced into a 1.5-tesla (T) magnetic resonance imaging (MRI) unit. Most of the prostheses were then placed in a water-filled Petri dish and reintroduced into the MRI unit. Eventual in vitro displacement was assessed visually by two means. In situ testing was done by implanting a piston in a cadaveric temporal bone and performing MR sequences ; any possible displacement was then assessed by CT scan and under microscopic vision. None of the prostheses was displaced in the empty Petri dish. However, while in the water-filled Petri dish, three of these moved with the flux. The implanted piston in the temporal bone did not move. The displacement of three of the prostheses in water is not relevant in real clinical situations. MRI can thus be considered safe in usual clinical settings, as far as our studied implants are concerned.

Simulation of a Hydraulic Pump Control Valve

NASA Technical Reports Server (NTRS)

Molen, G. Vander; Akers, A.

1987-01-01

This paper describes the mode of operation of a control valve assembly that is used with a hydraulic pump. The operating system of the valve is modelled in a simplified form, and an analogy for hydraulic resonance of the pressure sensing system is presented. For the control valve investigated, air entrainment, length and diameter of the resonator neck, and valve mass produced the greatest shift in resonant frequency. Experimental work was conducted on the hydraulic system so that the resonance levels and frequencies could be measured and the accuracy of the theory verified. The results obtained make it possible to evaluate what changes to any of the variables considered would be most effective in driving the second harmonic frequency above the operating range.

Demo of Active Resonators on the Active Noise Control Fan

NASA Image and Video Library

1998-10-01

NASA has been involved in several projects to reduce aircraft engine noise. In the 1990s Active Noise Control was investigated as a potential method to reduce aircraft engine noise. A description and demonstration of Active Resonators on the Active Noise Control Fan is shown in this video.

Optical Phased Array Using Guided Resonance with Backside Reflectors

NASA Technical Reports Server (NTRS)

Horie, Yu (Inventor); Arbabi, Amir (Inventor); Faraon, Andrei (Inventor)

2016-01-01

Methods and systems for controlling the phase of electromagnetic waves are disclosed. A device can consist of a guided resonance grating layer, a spacer, and a reflector. A plurality of devices, arranged in a grid pattern, can control the phase of reflected electromagnetic phase, through refractive index control. Carrier injection, temperature control, and optical beams can be applied to control the refractive index.

Optical phased array using guided resonance with backside reflectors

DOEpatents

Horie, Yu; Arbabi, Amir; Faraon, Andrei

2016-11-01

Methods and systems for controlling the phase of electromagnetic waves are disclosed. A device can consist of a guided resonance grating layer, a spacer, and a reflector. A plurality of devices, arranged in a grid pattern, can control the phase of reflected electromagnetic phase, through refractive index control. Carrier injection, temperature control, and optical beams can be applied to control the refractive index.

Optical phased array using guided resonance with backside reflectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Horie, Yu; Arbabi, Amir; Faraon, Andrei

2018-03-13

Methods and systems for controlling the phase of electromagnetic waves are disclosed. A device can consist of a guided resonance grating layer, a spacer, and a reflector. A plurality of devices, arranged in a grid pattern, can control the phase of reflected electromagnetic phase, through refractive index control. Carrier injection, temperature control, and optical beams can be applied to control the refractive index.

Optical Phased Array Using Guided Resonance with Backside Reflectors

NASA Technical Reports Server (NTRS)

Horie, Yu (Inventor); Arbabi, Amir (Inventor); Faraon, Andrei (Inventor)

2018-01-01

Methods and systems for controlling the phase of electromagnetic waves are disclosed. A device can consist of a guided resonance grating layer, a spacer, and a reflector. A plurality of devices, arranged in a grid pattern, can control the phase of reflected electromagnetic phase, through refractive index control. Carrier injection, temperature control, and optical beams can be applied to control the refractive index.

Experimental and theoretical sound transmission. [reduction of interior noise in aircraft

NASA Technical Reports Server (NTRS)

Roskam, J.; Muirhead, V. U.; Smith, H. W.; Durenberger, D. W.

1978-01-01

The capabilities of the Kansas University- Flight Research Center for investigating panel sound transmission as a step toward the reduction of interior noise in general aviation aircraft were discussed. Data obtained on panels with holes, on honeycomb panels, and on various panel treatments at normal incidence were documented. The design of equipment for panel transmission loss tests at nonnormal (slanted) sound incidence was described. A comprehensive theory-based prediction method was developed and shows good agreement with experimental observations of the stiffness controlled, the region, the resonance controlled region, and the mass-law region of panel vibration.

Secular dynamics of an exterior test particle: the inverse Kozai and other eccentricity-inclination resonances

NASA Astrophysics Data System (ADS)

Vinson, Benjamin R.; Chiang, Eugene

2018-03-01

The behaviour of an interior test particle in the secular three-body problem has been studied extensively. A well-known feature is the Lidov-Kozai resonance in which the test particle's argument of periastron librates about ±90° and large oscillations in eccentricity and inclination are possible. Less explored is the inverse problem: the dynamics of an exterior test particle and an interior perturber. We survey numerically the inverse secular problem, expanding the potential to hexadecapolar order and correcting an error in the published expansion. Four secular resonances are uncovered that persist in full N-body treatments (in what follows, ϖ and Ω are the longitudes of periapse and of ascending node, ω is the argument of periapse, and subscripts 1 and 2 refer to the inner perturber and the outer test particle): (i) an orbit-flipping quadrupole resonance requiring a non-zero perturber eccentricity e1, in which Ω2 - ϖ1 librates about ±90°; (ii) a hexadecapolar resonance (the `inverse Kozai' resonance) for perturbers that are circular or nearly so and inclined by I ≃ 63°/117°, in which ω2 librates about ±90° and which can vary the particle eccentricity by Δe2 ≃ 0.2 and lead to orbit crossing; (iii) an octopole `apse-aligned' resonance at I ≃ 46°/107° wherein ϖ2 - ϖ1 librates about 0° and Δe2 grows with e1; and (iv) an octopole resonance at I ≃ 73°/134° wherein ϖ2 + ϖ1 - 2Ω2 librates about 0° and Δe2 can be as large as 0.3 for small but non-zero e1. Qualitatively, the more eccentric the perturber, the more the particle's eccentricity and inclination vary; also, more polar orbits are more chaotic. Our solutions to the inverse problem have potential application to the Kuiper belt and debris discs, circumbinary planets, and hierarchical stellar systems.

Dewar Testing of Coaxial Resonators at MSU

DOE Office of Scientific and Technical Information (OSTI.GOV)

Popielarski, J; Facco, A; Hodek, M

2012-07-01

Michigan State University is currently testing prototype and production cavities for two accelerator projects. 80.5 MHz {beta} = 0.085 quarter wave resonators (QWR) are being produced as part of a cryomodule for ReA3. 322 MHz {beta} = 0.53 half wave resonators (HWR) are being prototyped for a driver linac for the Facility for Rare Isotope Beams. This paper will discuss test results and how different cavity preparations effect cavity performs. Also various diagnostics methods have been developed, such as second sound quench location determination, and temperature mapping to determine hot spots from defects and multipacting location.

Design and application of a new control system for tokamak ECRH power supply

NASA Astrophysics Data System (ADS)

Hao, Xu; Zhang, Jian; Huang, Yiyun

2016-03-01

The biggest challenge of designing and building tokamak electron cyclotron resonance heating (ECRH) pulse step modulation (PSM) power supply is satisfying its required output voltage rising time to be less than 100 µs while suppressing the voltage overshoot to be no more than 1%. To fulfill the two requirements, a new control strategy with startup time in microsecond range is proposed in this paper, and a new control system to realize the control strategy is introduced. The control system was built and tested on 60 kV/50 A ECRH power supply. The experimental results indicate that the control system can restrain the overshoot effectively, increase response speed, and obviously improve the dynamic characteristics of the PSM power supply system. Thus, the proposed control system helps the PSM power supply to meet the design specifications.

Screening for cognitive impairment in older individuals. Validation study of a computer-based test.

PubMed

Green, R C; Green, J; Harrison, J M; Kutner, M H

1994-08-01

This study examined the validity of a computer-based cognitive test that was recently designed to screen the elderly for cognitive impairment. Criterion-related validity was examined by comparing test scores of impaired patients and normal control subjects. Construct-related validity was computed through correlations between computer-based subtests and related conventional neuropsychological subtests. University center for memory disorders. Fifty-two patients with mild cognitive impairment by strict clinical criteria and 50 unimpaired, age- and education-matched control subjects. Control subjects were rigorously screened by neurological, neuropsychological, imaging, and electrophysiological criteria to identify and exclude individuals with occult abnormalities. Using a cut-off total score of 126, this computer-based instrument had a sensitivity of 0.83 and a specificity of 0.96. Using a prevalence estimate of 10%, predictive values, positive and negative, were 0.70 and 0.96, respectively. Computer-based subtests correlated significantly with conventional neuropsychological tests measuring similar cognitive domains. Thirteen (17.8%) of 73 volunteers with normal medical histories were excluded from the control group, with unsuspected abnormalities on standard neuropsychological tests, electroencephalograms, or magnetic resonance imaging scans. Computer-based testing is a valid screening methodology for the detection of mild cognitive impairment in the elderly, although this particular test has important limitations. Broader applications of computer-based testing will require extensive population-based validation. Future studies should recognize that normal control subjects without a history of disease who are typically used in validation studies may have a high incidence of unsuspected abnormalities on neurodiagnostic studies.

200 MW S-band traveling wave resonant ring development at IHEP

NASA Astrophysics Data System (ADS)

Zhou, Zu-Sheng; Chi, Yun-Long; Git, Meng-Ping; Pei, Guo-Xi

2010-03-01

The resonant-ring is a traveling wave circuit, which is used to produce high peak power with comparatively smaller stored energy. The application to be considered is its use as a high power simulator mainly for testing the klystron ceramic output window, as well as for high power microwave transmission devices. This paper describes the principle of a resonant ring and introduces the structure and property of the newly constructed traveling wave resonant ring at IHEP. Our goal is to produce a 200 MW class resonant ring at 2.856 GHz with a pulse length of 2 μs and repetition rate of 25 Hz. The installation, commissioning and testing of the ring have been completed and a peak power of 200 MW at 3 μs has been achieved. The conditioning results show that all the parameters of the resonant ring reach the design goals.

Epitaxial Garnets and Hexagonal Ferrites.

DTIC Science & Technology

1980-02-28

shaped LPE garnet samples with 31.5um film thickness. We were informed that initial evalu- ation showed acceptably low insertion loss and that the material...frequencies above 25 GHz. c. Furnish up to eight (8) liquid phase epitaxy yttrium iron garnet films to RADC/EEA for testing and evaluation. These tasks...a "Method for Controlling Resonance Frequency of Yttrium Iron Garnet Films ." A patent, "Epitaxial Growth of M-type Hexagonal Ferrite Films on Spinel

The Design and Testing of a High-Temperature Graphite Dilatometer

DTIC Science & Technology

1992-06-24

characterization of its CTE is of little significance. Practical candidates are silica (fused quartz glass), Zerodur -type glass ceramics (5 x 10- 8 C-1 ), and...titanium silicates (< 5 x IO17 *C-1 ). Partially crystallized glasses, such as Zerodur , are limited to about 6006C. Silica can be subjected to almost...electronics, solid-state lasers , optical propagation and communications; cw and pulsed chemical laser development, optical resonators, beam control

Immune function and brain abnormalities in patients with systemic lupus erythematosus without overt neuropsychiatric manifestations.

PubMed

Kozora, E; Filley, C M; Zhang, L; Brown, M S; Miller, D E; Arciniegas, D B; Pelzman, J L; West, S G

2012-04-01

This study examined the relationship between immune, cognitive and neuroimaging assessments in subjects with systemic lupus erythematosus (SLE) without histories of overt neuropsychiatric (NP) disorders. In total, 84 subjects with nonNPSLE and 37 healthy controls completed neuropsychological testing from the American College of Rheumatology SLE battery. Serum autoantibody and cytokine measures, volumetric magnetic resonance imaging, and magnetic resonance spectroscopy data were collected on a subset of subjects. NonNPSLE subjects had lower scores on measures of visual/complex attention, visuomotor speed and verbal memory compared with controls. No clinically significant differences between nonNPSLE patients and controls were found on serum measures of lupus anticoagulant, anticardiolipin antibodies, beta 2-glycoproteins, or pro-inflammatory cytokines (interleukin (IL)-1, IL-6, interferon alpha (IFN-alpha), and interferon gamma (IFN-gamma)). Higher scores on a global cognitive impairment index and a memory impairment index were correlated with lower IFN-alpha. Few associations between immune functions and neuroimaging parameters were found. Results indicated that nonNPSLE patients demonstrated cognitive impairment but not immune differences compared with controls. In these subjects, who were relatively young and with mild disease, no relationship between cognitive dysfunction, immune parameters, or previously documented neuroimaging abnormalities were noted. Immune measures acquired from cerebrospinal fluid instead of serum may yield stronger associations.

Impulse oscillometry and obesity in children.

PubMed

Assumpção, Maíra S de; Ribeiro, José D; Wamosy, Renata M G; Figueiredo, Fernanda C X S de; Parazzi, Paloma L F; Schivinski, Camila I S

2017-09-08

To compare impulse oscillometry system parameters of normal-weight children with overweight and obese children. All participants were submitted to the evaluation of lung function (spirometry and impulse oscillometry) following the American Thoracic Society standards. The evaluation of respiratory mechanics was performed using the Jaeger™ MasterScreen™ Impulse Oscillometry System (Erich Jaeger, Germany), three tests were recorded, with acquisition for at least 20s. The study included 81 children (30 in the control group, 21 in the overweight group, and 30 the in obesity group), matched for age and sex. Regarding spirometry data, obesity group showed higher numerical values in relation to the control group; however, there were no significant differences among the three groups. For impulse oscillometry parameters, there was a difference between control group and obesity group for respiratory impedance (p=0.036), resistance at 5hertz (p=0.026), resonant frequency (p=0.029), and reactance area (p=0.014). For the parameters expressed in percentage of predicted, there were differences in resistance at 5 hertz, resonant frequency, and reactance area between control group and obesity group. Obese children showed increased oscillometry parameters values representative of airway obstruction, compared to normal-weight children. Changes in some oscillometry parameters can already be observed in overweight school-aged children. Copyright © 2017 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

Functional magnetic resonance imaging of working memory and response inhibition in children with mild traumatic brain injury.

PubMed

Krivitzky, Lauren S; Roebuck-Spencer, Tresa M; Roth, Robert M; Blackstone, Kaitlin; Johnson, Chad P; Gioia, Gerard

2011-11-01

The current pilot study examined functional magnetic resonance imaging (fMRI) activation in children with mild traumatic brain injury (mTBI) during tasks of working memory and inhibitory control, both of which are vulnerable to impairment following mTBI. Thirteen children with symptomatic mTBI and a group of controls completed a version of the Tasks of Executive Control (TEC) during fMRI scanning. Both groups showed greater prefrontal activation in response to increased working memory load. Activation patterns did not differ between groups on the working memory aspects of the task, but children with mTBI showed greater activation in the posterior cerebellum with the addition of a demand for inhibitory control. Children with mTBI showed greater impairment on symptom report and "real world" measures of executive functioning, but not on traditional "paper and pencil" tasks. Likewise, cognitive testing did not correlate significantly with imaging results, whereas increased report of post-concussive symptoms were correlated with increased cerebellar activation. Overall, results provide some evidence for the utility of symptom report as an indicator of recovery and the hypothesis that children with mTBI may experience disrupted neural circuitry during recovery. Limitations of the study included a small sample size, wide age range, and lack of in-scanner accuracy data.

Overvoltage protection system for wireless power transfer systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chambon, Paul H.; Jones, Perry T.; Miller, John M.

A wireless power transfer overvoltage protection system is provided. The system includes a resonant receiving circuit. The resonant receiving circuit includes an inductor, a resonant capacitor and a first switching device. The first switching device is connected the ends of the inductor. The first switching device has a first state in which the ends of the inductor are electrically coupled to each other through the first switching device, and a second state in which the inductor and resonant capacitor are capable of resonating. The system further includes a control module configured to control the first switching device to switching betweenmore » the first state and the second state when the resonant receiving circuit is charging a load and a preset condition is satisfied and otherwise, the first switching device is maintained in the first state.« less

Real-Time Functional Magnetic Resonance Imaging Amygdala Neurofeedback Changes Positive Information Processing in Major Depressive Disorder.

PubMed

Young, Kymberly D; Misaki, Masaya; Harmer, Catherine J; Victor, Teresa; Zotev, Vadim; Phillips, Raquel; Siegle, Greg J; Drevets, Wayne C; Bodurka, Jerzy

2017-10-15

In participants with major depressive disorder who are trained to upregulate their amygdalar hemodynamic responses during positive autobiographical memory recall with real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) training, depressive symptoms diminish. This study tested whether amygdalar rtfMRI-nf also changes emotional processing of positive and negative stimuli in a variety of behavioral and imaging tasks. Patients with major depressive disorder completed two rtfMRI-nf sessions (18 received amygdalar rtfMRI-nf, 16 received control parietal rtfMRI-nf). One week before and following rtfMRI-nf training, participants performed tasks measuring responses to emotionally valenced stimuli including a backward-masking task, which measures the amygdalar hemodynamic response to emotional faces presented for traditionally subliminal duration and followed by a mask, and the Emotional Test Battery in which reaction times and performance accuracy are measured during tasks involving emotional faces and words. During the backward-masking task, amygdalar responses increased while viewing masked happy faces but decreased to masked sad faces in the experimental versus control group following rtfMRI-nf. During the Emotional Test Battery, reaction times decreased to identification of positive faces and during self-identification with positive words and vigilance scores increased to positive faces and decreased to negative faces during the faces dot-probe task in the experimental versus control group following rtfMRI-nf. rtfMRI-nf training to increase the amygdalar hemodynamic response to positive memories was associated with changes in amygdalar responses to happy and sad faces and improved processing of positive stimuli during performance of the Emotional Test Battery. These results may suggest that amygdalar rtfMRI-nf training alters responses to emotional stimuli in a manner similar to antidepressant pharmacotherapy. Copyright © 2017 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

A functional magnetic resonance imaging study of working memory abnormalities in schizophrenia.

PubMed

Johnson, Matthew R; Morris, Nicholas A; Astur, Robert S; Calhoun, Vince D; Mathalon, Daniel H; Kiehl, Kent A; Pearlson, Godfrey D

2006-07-01

Previous neuroimaging studies of working memory (WM) in schizophrenia, typically focusing on dorsolateral prefrontal cortex, yield conflicting results, possibly because of varied choice of tasks and analysis techniques. We examined neural function changes at several WM loads to derive a more complete picture of WM dysfunction in schizophrenia. We used a version of the Sternberg Item Recognition Paradigm to test WM function at five distinct loads. Eighteen schizophrenia patients and 18 matched healthy controls were scanned with functional magnetic resonance imaging at 3 Tesla. Patterns of both overactivation and underactivation in patients were observed depending on WM load. Patients' activation was generally less responsive to load changes than control subjects', and different patterns of between-group differences were observed for memory encoding and retrieval. In the specific case of successful retrieval, patients recruited additional neural circuits unused by control subjects. Behavioral effects were generally consistent with these imaging results. Differential findings of overactivation and underactivation may be attributable to patients' decreased ability to focus and allocate neural resources at task-appropriate levels. Additionally, differences between encoding and retrieval suggest that WM dysfunction may be manifested differently during the distinct phases of encoding, maintenance, and retrieval.

Bandwidth-limited control and ringdown suppression in high-Q resonators.

PubMed

Borneman, Troy W; Cory, David G

2012-12-01

We describe how the transient behavior of a tuned and matched resonator circuit and a ringdown suppression pulse may be integrated into an optimal control theory (OCT) pulse-design algorithm to derive control sequences with limited ringdown that perform a desired quantum operation in the presence of resonator distortions of the ideal waveform. Inclusion of ringdown suppression in numerical pulse optimizations significantly reduces spectrometer deadtime when using high quality factor (high-Q) resonators, leading to increased signal-to-noise ratio (SNR) and sensitivity of inductive measurements. To demonstrate the method, we experimentally measure the free-induction decay of an inhomogeneously broadened solid-state free radical spin system at high Q. The measurement is enabled by using a numerically optimized bandwidth-limited OCT pulse, including ringdown suppression, robust to variations in static and microwave field strengths. We also discuss the applications of pulse design in high-Q resonators to universal control of anisotropic-hyperfine coupled electron-nuclear spin systems via electron-only modulation even when the bandwidth of the resonator is significantly smaller than the hyperfine coupling strength. These results demonstrate how limitations imposed by linear response theory may be vastly exceeded when using a sufficiently accurate system model to optimize pulses of high complexity. Copyright © 2012 Elsevier Inc. All rights reserved.

Preoperative Magnetic Resonance Imaging in Patients With Stage I Invasive Ductal Breast Cancer: A Prospective Randomized Study.

PubMed

Brück, N; Koskivuo, I; Boström, P; Saunavaara, J; Aaltonen, R; Parkkola, R

2018-03-01

Preoperative magnetic resonance imaging has become an important complementary imaging technique in patients with breast cancer, providing additional information for preoperative local staging. Magnetic resonance imaging is recommended selectively in lobular breast cancer and in patients with dense breast tissue in the case when mammography and ultrasound fail to fully evaluate the lesion, but the routine use of magnetic resonance imaging in all patients with invasive ductal carcinoma is controversial. The purpose of this randomized study was to investigate the diagnostic value of preoperative magnetic resonance imaging and its impact on short-term surgical outcome in newly diagnosed unifocal stage I invasive ductal carcinoma. A total of 100 patients were randomized to either receive preoperative breast magnetic resonance imaging or to be scheduled directly to operation without magnetic resonance imaging on a 1:1 basis. There were 50 patients in both study arms. In 14 patients (28%), breast magnetic resonance imaging detected an additional finding and seven of them were found to be malignant. Six additional cancer foci were found in the ipsilateral breast and one in the contralateral breast. Magnetic resonance imaging findings caused a change in planned surgical management in 10 patients (20%). Mastectomy was performed in six patients (12%) in the magnetic resonance imaging group and in two patients (4%) in the control group ( p = 0.140). The breast reoperation rate was 14% in the magnetic resonance imaging group and 24% in the control group ( p = 0.202). The mean interval between referral and first surgical procedure was 34 days in the magnetic resonance imaging group and 21 days in the control group ( p < 0.001). Preoperative magnetic resonance imaging may be beneficial for some patients with early-stage invasive ductal carcinoma, but its routine use is not recommended without specific indications.

Can Lactobacillus acidophilus improve minimal hepatic encephalopathy? A neurometabolite study using magnetic resonance spectroscopy.

PubMed

Ziada, Dina H; Soliman, Hanan H; El Yamany, Saher A; Hamisa, Manal F; Hasan, Azza M

2013-09-01

Minimal hepatic encephalopathy (MHE) is diagnosed when hepatic patients perform worse on psychometric tests compared to healthy controls. This study aimed to evaluate probiotics as alternative therapy in MHE. This is an open-label randomised controlled trial, performed in the Department of Tropical Medicine and Infectious Diseases, Tanta University Hospitals, from March 2010 to January 2012. A total of 90 patients with MHE were allocated by simple randomisation to three parallel equal groups. Group A received lactulose, group B a probiotic (Lactobacillus acidophilus) and group C served as the control. After informed consent, patients were tested for gut micrecology, fasting blood ammonia, liver functions and magnetic resonance spectroscopy (MRS) examination to study brain metabolites, mainly choline (Cho), myo-inositol (mI), glutamine+glutamate (Glx) and creatinin (Cre). Patients who developed overt encephalopathy were excluded from analysis. The whole battery of investigations was repeated in the same order after 4weeks. The probiotic was better tolerated than lactulose. The relative risk reduction (RRR) of developing overt encephalopathy was 60% in the case of lactulose and 80% in the case of probiotic, with a number needed to treat (NNT) of 2.4 and 2.3, respectively. The differential but not total microecology count was significantly shifted towards saccharolytic rather than proteolytic bacteria. The mI/Cre and (Cho+mI)/Glx ratios were significantly increased and the Glx/Cre ratio was significantly reduced after 1month-follow-up in the probiotic group compared to the lactulose group and in both treatment groups compared to the control group. Both probiotic and lactulose therapy can improve blood ammonia and psychometric tests in MHE and reduce the risk of developing overt encephalopathy. MRS showed more improvement in the levels of brain neurometabolites in the probiotic group. Copyright © 2013 Arab Journal of Gastroenterology. Published by Elsevier Ltd. All rights reserved.

Sensitive spin detection using an on-chip SQUID-waveguide resonator

NASA Astrophysics Data System (ADS)

Yue, G.; Chen, L.; Barreda, J.; Bevara, V.; Hu, L.; Wu, L.; Wang, Z.; Andrei, P.; Bertaina, S.; Chiorescu, I.

2017-11-01

Precise detection of spin resonance is of paramount importance to achieve coherent spin control in quantum computing. We present a setup for spin resonance measurements, which uses a dc-SQUID flux detector coupled to an antenna from a coplanar waveguide. The SQUID and the waveguide are fabricated from a 20 nm Nb thin film, allowing high magnetic field operation with the field applied parallel to the chip. We observe a resonance signal between the first and third excited states of Gd spins S = 7/2 in a CaWO4 crystal, relevant for state control in multi-level systems.

Tunable multiwalled nanotube resonator

DOEpatents

Jensen, Kenneth J; Girit, Caglar O; Mickelson, William E; Zettl, Alexander K; Grossman, Jeffrey C

2013-11-05

A tunable nanoscale resonator has potential applications in precise mass, force, position, and frequency measurement. One embodiment of this device consists of a specially prepared multiwalled carbon nanotube (MWNT) suspended between a metal electrode and a mobile, piezoelectrically controlled contact. By harnessing a unique telescoping ability of MWNTs, one may controllably slide an inner nanotube core from its outer nanotube casing, effectively changing its length and thereby changing the tuning of its resonance frequency. Resonant energy transfer may be used with a nanoresonator to detect molecules at a specific target oscillation frequency, without the use of a chemical label, to provide label-free chemical species detection.

Tunable multiwalled nanotube resonator

DOEpatents

Zettl, Alex K [Kensington, CA; Jensen, Kenneth J [Berkeley, CA; Girit, Caglar [Albany, CA; Mickelson, William E [San Francisco, CA; Grossman, Jeffrey C [Berkeley, CA

2011-03-29

A tunable nanoscale resonator has potential applications in precise mass, force, position, and frequency measurement. One embodiment of this device consists of a specially prepared multiwalled carbon nanotube (MWNT) suspended between a metal electrode and a mobile, piezoelectrically controlled contact. By harnessing a unique telescoping ability of MWNTs, one may controllably slide an inner nanotube core from its outer nanotube casing, effectively changing its length and thereby changing the tuning of its resonance frequency. Resonant energy transfer may be used with a nanoresonator to detect molecules at a specific target oscillation frequency, without the use of a chemical label, to provide label-free chemical species detection.

Magnetic Resonance Spectroscopy for Evaluating Portal-Systemic Encephalopathy in Patients with Chronic Hepatic Schistosomiasis Japonicum.

PubMed

Li, Ying; Mei, Lihong; Qiang, Jinwei; Ju, Shuai; Zhao, Shuhui

2016-12-01

Portal-systemic encephalopathy (PSE) is classified as type B hepatic encephalopathy. Portal-systemic shunting rather than liver dysfunction is the main cause of PSE in chronic hepatic schistosomiasis japonicum (HSJ) patients. Owing to lack of detectable evidence of intrinsic liver disease, chronic HSJ patients with PSE are frequently clinically undetected or misdiagnosed, especially chronic HSJ patients with covert PSE (subclinical encephalopathy). In this study, we investigated whether magnetic resonance spectroscopy (MRS) could be a useful tool for diagnosing PSE in chronic HSJ patients. Magnetic resonance (MR) T1-weighted imaging, diffusion-weighted imaging, and MRS were performed in 41 chronic HSJ patients with suspected PSE and in 21 age-matched controls. The T1 signal intensity index (T1SI) and apparent diffusion coefficient (ADC) value were obtained in the Globus pallidus. Liver function was also investigated via serum ammonia and liver function tests. Higher T1SI and ADC values, increased lactate and glutamine levels, and decreased myo-inositol were found in the bilateral Globus pallidus in chronic HSJ patients with PSE. No significantly abnormal serum ammonia or liver function tests were observed in chronic HSJ patients with PSE. On the basis of these findings, we propose a diagnostic procedure for PSE in chronic HSJ patients. This study reveals that MRS can be useful for diagnosing PSE in chronic HSJ patients.

Liquid Motion Experiment Flight Test Results

NASA Technical Reports Server (NTRS)

Chato David J.; Dalton, Penni J.; Dodge, Franklin T.; Green, Steve

1998-01-01

The Liquid Motion Experiment (LME), designed to study the effects of liquid motion in rotating tanks, was flown on STS 84. LME was essentially a spin table that created a realistic nutation motion of scale-model tanks containing liquid. TWo spherical and two cylindrical transparent tanks were tested simultaneously, and three sets of such tanks were employed to vary liquid viscosity, fill level, and propellant management device (PMD) design. All the tanks were approximately 4.5 inches diameter. The primary test measurements were the radial and tangential torques exerted on the tanks by the liquid. Resonant frequencies and damping of the liquid oscillations were determined by sine sweep tests. For a given tank shape, the resonant frequency depended on fill level. For the cylindrical tanks, the resonances had somewhat different frequencies for the tangential axis (0.55 to 0.75 times spin rate) and the radial axis (0.73 to 0.78 times spin rate), and the tangential axis resonance agreed more closely with available analytical models. For the spherical tanks, the resonant frequencies were between 0.74 to 0.77 times the spin rate and were the same for the tangential and radial axes. The damping coefficients varied from about I% to 3% of critical, depending on tank shape, fill level, and liquid viscosity. 'Me viscous energy dissipation rates of the liquid oscillations were determined from sine dwell tests. The LME energy dissipation rates varied from 0.3 to 0.5 times the estimates obtained from scaling previous ground tests and spacecraft flight data. The PNDs sometimes enhanced the resonances and energy dissipation rates and sometimes decreased them, which points out the need to understand better the effects of PMD on liquid motion as a function of PMD and tank design.

Split Hopkinson resonant bar test for sonic-frequency acoustic velocity and attenuation measurements of small, isotropic geological samples.

PubMed

Nakagawa, Seiji

2011-04-01

Mechanical properties (seismic velocities and attenuation) of geological materials are often frequency dependent, which necessitates measurements of the properties at frequencies relevant to a problem at hand. Conventional acoustic resonant bar tests allow measuring seismic properties of rocks and sediments at sonic frequencies (several kilohertz) that are close to the frequencies employed for geophysical exploration of oil and gas resources. However, the tests require a long, slender sample, which is often difficult to obtain from the deep subsurface or from weak and fractured geological formations. In this paper, an alternative measurement technique to conventional resonant bar tests is presented. This technique uses only a small, jacketed rock or sediment core sample mediating a pair of long, metal extension bars with attached seismic source and receiver-the same geometry as the split Hopkinson pressure bar test for large-strain, dynamic impact experiments. Because of the length and mass added to the sample, the resonance frequency of the entire system can be lowered significantly, compared to the sample alone. The experiment can be conducted under elevated confining pressures up to tens of MPa and temperatures above 100 [ordinal indicator, masculine]C, and concurrently with x-ray CT imaging. The described split Hopkinson resonant bar test is applied in two steps. First, extension and torsion-mode resonance frequencies and attenuation of the entire system are measured. Next, numerical inversions for the complex Young's and shear moduli of the sample are performed. One particularly important step is the correction of the inverted Young's moduli for the effect of sample-rod interfaces. Examples of the application are given for homogeneous, isotropic polymer samples, and a natural rock sample. © 2011 American Institute of Physics

Dynamic frequency tuning of electric and magnetic metamaterial response

DOEpatents

O'Hara, John F; Averitt, Richard; Padilla, Willie; Chen, Hou-Tong

2014-09-16

A geometrically modifiable resonator is comprised of a resonator disposed on a substrate, and a means for geometrically modifying the resonator. The geometrically modifiable resonator can achieve active optical and/or electronic control of the frequency response in metamaterials and/or frequency selective surfaces, potentially with sub-picosecond response times. Additionally, the methods taught here can be applied to discrete geometrically modifiable circuit components such as inductors and capacitors. Principally, controlled conductivity regions, using either reversible photodoping or voltage induced depletion activation, are used to modify the geometries of circuit components, thus allowing frequency tuning of resonators without otherwise affecting the bulk substrate electrical properties. The concept is valid over any frequency range in which metamaterials are designed to operate.

Multilayered metal-insulator nanocavities: toward tunable multi-resonance nano-devices for integrated optics

NASA Astrophysics Data System (ADS)

Song, Junyeob; Zhou, Wei

2017-02-01

Plasmonic nanocavities can control light flows and enhance light-mater interactions at subwavelength scale, and thus can potentially be used as nanoscale components in integrated optics systems either for passive optical coupling, or for active optical modulation and emission. In this work, we investigated a new type of multilayered metal-insulator optical nanocavities that can support multiple localized plasmon resonances with ultra-small mode volumes. The total number of resonance peaks and their resonance wavelengths can be freely and accurately controlled by simple geometric design rules. Multi-resonance plasmonic nanocavities can serve as a nanoscale wavelength-multiplexed optical components in integrated optics systems, such as optical couplers, light emitters, nanolasers, optical sensors, and optical modulators.

Toward wideband steerable acoustic metasurfaces with arrays of active electroacoustic resonators

NASA Astrophysics Data System (ADS)

Lissek, Hervé; Rivet, Etienne; Laurence, Thomas; Fleury, Romain

2018-03-01

We introduce an active concept for achieving acoustic metasurfaces with steerable reflection properties, effective over a wide frequency band. The proposed active acoustic metasurface consists of a surface array of subwavelength loudspeaker diaphragms, each with programmable individual active acoustic impedances allowing for local control over the different reflection phases over the metasurface. The active control framework used for controlling the reflection phase over the metasurface is derived from the Active Electroacoustic Resonator concept. Each unit-cell simply consists of a current-driven electrodynamic loudspeaker in a closed box, whose acoustic impedance at the diaphragm is judiciously adjusted by connecting an active electrical control circuit. The control is known to achieve a wide variety of acoustic impedances on a single loudspeaker diaphragm used as an acoustic resonator, with the possibility to shift its resonance frequency by more than one octave. This paper presents a methodology for designing such active metasurface elements. An experimental validation of the achieved individual reflection coefficients is presented, and full wave simulations present a few examples of achievable reflection properties, with a focus on the bandwidth of operation of the proposed control concept.

A 10kW series resonant converter design, transistor characterization, and base-drive optimization

NASA Technical Reports Server (NTRS)

Robson, R.; Hancock, D.

1981-01-01

Transistors are characterized for use as switches in resonant circuit applications. A base drive circuit to provide the optimal base drive to these transistors under resonant circuit conditions is developed and then used in the design, fabrication and testing of a breadboard, spaceborne type 10 kW series resonant converter.

Convergence and divergence of neuroanatomic correlates and executive task performance in healthy controls and psychiatric participants.

PubMed

Ming-Tak Chung, Dennis; Jerram, Matthew W; Lee, Jonathan K; Katz, Harvey; Gansler, David A

2013-12-30

The associations between brain matter volume in the cerebral cortex and set shifting and attentional control as operationalized by the Wisconsin Card Sort Test (WCST) and Condition Three of the Delis-Kaplan version of the Color Word Interference Test (CWIT) were investigated in 15 healthy controls and 16 heterogeneously diagnosed psychiatric patients with self-control problems using voxel based morphometry. Both groups underwent standardized magnetic resonance imaging and neuropsychological assessment. WCST and CWIT variables, and a composite, were regressed across the whole brain. Although CWIT performance levels were the same in both groups, neuroanatomic correlates for the psychiatric participants invoked the left hemisphere language system, but the bilateral dorsal attention system in the healthy controls. On its own, no neuroanatomic correlates were observed for the WCST. But when part of a composite with CWIT, neuroanatomic correlates in the dorsal attention system emerged for the psychiatric participants. Psychometric combinations of manifest executive task variables may best represent higher level latent neuro-cognitive control systems. Factor analytic studies of neuropsychological test performances suggest the constructs being measured are the same across psychiatric and non-diagnosed participants, however, imaging modalities indicate the relevant neural architecture can vary by group. © 2013 Elsevier Ireland Ltd. All rights reserved.

LABCOM resonator Phase 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keres, L.J.

1990-11-01

The purpose of this project was to develop quartz crystal resonator designs, production processes, and test capabilities for 5-MHz, 6.2-MHz, and 10-MHz resonators for Tactical Miniature Crystal Oscillator (TMXO) applications. GE Neutron Devices (GEND) established and demonstrated the capability to produce and test quartz crystal resonators for use in the TMXO developed by the US Army ERADCOM (now LABCOM). The goals in this project were based on the ERADCOM statement of work. The scope of work indicated that the resonator production facilities for this project would not be completely independent, but that they would be supported in part by equipmentmore » and processes in place at GEND used in US Department of Energy (DOE) work. In addition, provisions for production test equipment or or eventual technology transfer costs to a commercial supplier were clearly excluded from the scope of work. The demonstrated technical capability of the deep-etched blank design is feasible and practical. It can be manufactured in quantity with reasonable yield, and its performance is readily predictable. The ceramic flatpack is a very strong package with excellent hermeticity. The four-point mount supports the crystal to reasonable shock levels and does not perturb the resonator's natural frequency-temperature behavior. The package can be sealed with excellent yields. The high-temperature, high-vacuum processing developed for the TMXO resonator, including bonding the piezoid to its mount with conductive polyimide adhesive, is consistent with precision resonator fabrication. 1 fig., 6 tabs.« less

Single-Mode WGM Resonators Fabricated by Diamond Turning

NASA Technical Reports Server (NTRS)

Grudinin, Ivan; Maleki, Lute; Savchenkov, Anatoliy; Matsko, Andrewy; Strekalov, Dmitry; Iltchenko, Vladimir

2008-01-01

A diamond turning process has made possible a significant advance in the art of whispering-gallery-mode (WGM) optical resonators. By use of this process, it is possible to fashion crystalline materials into WGM resonators that have ultrahigh resonance quality factors (high Q values), are compact (ranging in size from millimeters down to tens of microns), and support single electromagnetic modes. This development combines and extends the developments reported in "Few- Mode Whispering-Gallery-Mode Resonators" (NPO-41256), NASA Tech Briefs, Vol. 30, No. 1 (January 2006), page 16a and "Fabrication of Submillimeter Axisymmetric Optical Components" (NPO-42056), NASA Tech Briefs, Vol. 31, No. 5 (May 2007), page 10a. To recapitulate from the first cited prior article: A WGM resonator of this special type consists of a rod, made of a suitable transparent material, from which protrudes a thin circumferential belt of the same material. The belt is integral with the rest of the rod and acts as a circumferential waveguide. If the depth and width of the belt are made appropriately small, then the belt acts as though it were the core of a single-mode optical fiber: the belt and the rod material adjacent to it support a single, circumferentially propagating mode or family of modes. To recapitulate from the second cited prior article: A major step in the fabrication of a WGM resonator of this special type is diamond turning or computer numerically controlled machining of a rod of a suitable transparent crystalline material on an ultrahigh-precision lathe. During the rotation of a spindle in which the rod is mounted, a diamond tool is used to cut the rod. A computer program is used to control stepping motors that move the diamond tool, thereby controlling the shape cut by the tool. Because the shape can be controlled via software, it is possible to choose a shape designed to optimize a resonator spectrum, including, if desired, to limit the resonator to supporting a single mode. After diamond turning, a resonator can be polished to increase its Q. By virtue of its largely automated, computer-controlled nature, the process is suitable for mass production of nominally identical single-mode WGM resonators. In a demonstration of the capabilities afforded by this development, a number of WGM resonators of various designs were fabricated side by side on the surface of a single CaF2 rod (see figure).

Effects of gadolinium-based MRI contrast agents on liver tissue.

PubMed

Mercantepe, Tolga; Tümkaya, Levent; Çeliker, Fatma Beyazal; Topal Suzan, Zehra; Çinar, Seda; Akyildiz, Kerimali; Mercantepe, Filiz; Yilmaz, Adnan

2018-04-01

MRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. To compare the effects on liver tissue of gadolinium-based MRI contrast agents in the light of biochemical and histopathological evaluation. Institutional Review Board (IRB)-approved controlled longitudinal study. In all, 32 male Sprague-Dawley rats were divided into a healthy control group subjected to no procedure (Group 1), a sham group (Group 2), a gadodiamide group (Group 3), and a gadoteric acid group (Group 4). Not applicable. Liver tissues removed at the end of the fifth week and evaluated pathologically (scored Knodell's histological activity index [HAI] method by two histopathologists) immunohistochemical (caspase-3 and biochemical tests (AST, ALT, TAS, TOS, and OSI method by Erel et al) were obtained. Differences between groups were analyzed using the nonparametric Kruskal-Wallis test followed by the Tamhane test, and one-way analysis of variance (ANOVA) followed by Turkey's HSD test. An increase was observed in histological activity scores in sections from rats administered gadodiamide and gadoteric acid, and in caspase-3, AST and ALT values (P < 0.05). In contrast, we determined no change in TOS (P = 0.568 and P = 0.094, respectively), TAS (P = 0.151 and P = 0.055, respectively), or OSI (P = 0.949 and P = 0.494, respectively) values. These data suggest that gadodiamide and gadoteric acid trigger hepatocellular necrosis and apoptosis by causing damage in hepatocytes, although no change occurs in total antioxidant and antioxidant capacity. 1 Technical Efficacy: Stage 4 J. Magn. Reson. Imaging 2018. © 2018 International Society for Magnetic Resonance in Medicine.

Vertebrobasilar system computed tomographic angiography in central vertigo

PubMed Central

Paşaoğlu, Lale

2017-01-01

Abstract The incidence of vertigo in the population is 20% to 30% and one-fourth of the cases are related to central causes. The aim of this study was to evaluate computed tomography angiography (CTA) findings of the vertebrobasilar system in central vertigo without stroke. CTA and magnetic resonance images of patients with vertigo were retrospectively evaluated. One hundred twenty-nine patients suspected of having central vertigo according to history, physical examination, and otological and neurological tests without signs of infarction on diffusion-weighted magnetic resonance imaging were included in the study. The control group included 120 patients with similar vascular disease risk factors but without vertigo. Vertebral and basilar artery diameters, hypoplasias, exit-site variations of vertebral artery, vertebrobasilar tortuosity, and stenosis of ≥50% detected on CTA were recorded for all patients. Independent-samples t test was used in variables with normal distribution, and Mann–Whitney U test in non-normal distribution. The difference of categorical variable distribution according to groups was analyzed with χ2 and/or Fisher exact test. Vertebral artery hypoplasia and ≥50% stenosis were seen more often in the vertigo group (P = 0.000, <0.001). Overall 78 (60.5%) vertigo patients had ≥50% stenosis, 54 (69.2%) had stenosis at V1 segment, 9 (11.5%) at V2 segment, 2 (2.5%) at V3 segment, and 13 (16.6%) at V4 segment. Both vertigo and control groups had similar basilar artery hypoplasia and ≥50% stenosis rates (P = 0.800, >0.05). CTA may be helpful to clarify the association between abnormal CTA findings of vertebral arteries and central vertigo. This article reveals the opportunity to diagnose posterior circulation abnormalities causing central vertigo with a feasible method such as CTA. PMID:28328808

Vertebrobasilar system computed tomographic angiography in central vertigo.

PubMed

Paşaoğlu, Lale

2017-03-01

The incidence of vertigo in the population is 20% to 30% and one-fourth of the cases are related to central causes. The aim of this study was to evaluate computed tomography angiography (CTA) findings of the vertebrobasilar system in central vertigo without stroke.CTA and magnetic resonance images of patients with vertigo were retrospectively evaluated. One hundred twenty-nine patients suspected of having central vertigo according to history, physical examination, and otological and neurological tests without signs of infarction on diffusion-weighted magnetic resonance imaging were included in the study. The control group included 120 patients with similar vascular disease risk factors but without vertigo. Vertebral and basilar artery diameters, hypoplasias, exit-site variations of vertebral artery, vertebrobasilar tortuosity, and stenosis of ≥50% detected on CTA were recorded for all patients. Independent-samples t test was used in variables with normal distribution, and Mann-Whitney U test in non-normal distribution. The difference of categorical variable distribution according to groups was analyzed with χ and/or Fisher exact test.Vertebral artery hypoplasia and ≥50% stenosis were seen more often in the vertigo group (P = 0.000, <0.001). Overall 78 (60.5%) vertigo patients had ≥50% stenosis, 54 (69.2%) had stenosis at V1 segment, 9 (11.5%) at V2 segment, 2 (2.5%) at V3 segment, and 13 (16.6%) at V4 segment. Both vertigo and control groups had similar basilar artery hypoplasia and ≥50% stenosis rates (P = 0.800, >0.05).CTA may be helpful to clarify the association between abnormal CTA findings of vertebral arteries and central vertigo.This article reveals the opportunity to diagnose posterior circulation abnormalities causing central vertigo with a feasible method such as CTA.

Resonance fluorescence revival in a voltage-controlled semiconductor quantum dot

NASA Astrophysics Data System (ADS)

Reigue, Antoine; Lemaître, Aristide; Gomez Carbonell, Carmen; Ulysse, Christian; Merghem, Kamel; Guilet, Stéphane; Hostein, Richard; Voliotis, Valia

2018-02-01

We demonstrate systematic resonance fluorescence recovery with near-unity emission efficiency in single quantum dots embedded in a charge-tunable device in a wave-guiding geometry. The quantum dot charge state is controlled by a gate voltage, through carrier tunneling from a close-lying Fermi sea, stabilizing the resonantly photocreated electron-hole pair. The electric field cancels out the charging/discharging mechanisms from nearby traps toward the quantum dots, responsible for the usually observed inhibition of the resonant fluorescence. Fourier transform spectroscopy as a function of the applied voltage shows a strong increase in the coherence time though not reaching the radiative limit. These charge controlled quantum dots can act as quasi-perfect deterministic single-photon emitters, with one laser pulse converted into one emitted single photon.

Rock Magnetic and Ferromagnetic Resonance Tests of Biogenic Magnetite in ALH84001

NASA Technical Reports Server (NTRS)

Kirschvink, J. L.; Kim, S.; Weiss, B. P.; Shannon, D. M.; Kobayashi, A. K.

2002-01-01

Three separate rock magnetic and ferromagnetic resonance tests support the hypothesis that between 25 and 50% of the fine-grained magnetite in the Martian meteorite ALH84001 was formed via biological processes. Additional information is contained in the original extended abstract.

Body Composition and Ectopic Lipid Changes With Biochemical Control of Acromegaly.

PubMed

Bredella, Miriam A; Schorr, Melanie; Dichtel, Laura E; Gerweck, Anu V; Young, Brian J; Woodmansee, Whitney W; Swearingen, Brooke; Miller, Karen K

2017-11-01

Acromegaly is characterized by growth hormone (GH) and insulinlike growth factor-1 (IGF-1) hypersecretion, and GH and IGF-1 play important roles in regulating body composition and glucose homeostasis. The purpose of our study was to investigate body composition including ectopic lipids, measures of glucose homeostasis, and gonadal steroids in patients with active acromegaly compared with age-, body mass index (BMI)-, and sex-matched controls and to determine changes in these parameters after biochemical control of acromegaly. Cross-sectional study of 20 patients with active acromegaly and 20 healthy matched controls. Prospective study of 16 patients before and after biochemical control of acromegaly. Body composition including ectopic lipids by magnetic resonance imaging/proton magnetic resonance spectroscopy; measures of glucose homeostasis by an oral glucose tolerance test; gonadal steroids. Patients with active acromegaly had lower mean intrahepatic lipid (IHL) and higher mean fasting insulin and insulin area under the curve (AUC) values than controls. Men with acromegaly had lower mean total testosterone, sex hormone-binding globulin, and estradiol values than male controls. After therapy, homeostasis model assessment of insulin resistance, fasting insulin level, and insulin AUC decreased despite an increase in IHL and abdominal and thigh adipose tissues and a decrease in muscle mass. Patients with acromegaly were characterized by insulin resistance and hyperinsulinemia but lower IHL compared with age-, BMI-, and sex-matched healthy controls. Biochemical control of acromegaly improved insulin resistance but led to a less favorable anthropometric phenotype with increased IHL and abdominal adiposity and decreased muscle mass. Copyright © 2017 Endocrine Society

Spine abnormalities depicted by magnetic resonance imaging in adolescent rowers.

PubMed

Maurer, Marvin; Soder, Ricardo Bernardi; Baldisserotto, Matteo

2011-02-01

Most lesions of the spine of athletes, which often are detected incidentally, do not cause important symptoms or make the athletes discontinue their physical activities. To better understand the significance of these lesions, new imaging studies have been conducted with asymptomatic athletes in several sports, aiming to detect potentially deleterious and disabling abnormalities. To compare the magnetic resonance imaging (MRI) lumbar spine findings in a group of asymptomatic adolescent rowers and in a control group of adolescents matched according to age and sex who do not practice any regular physical activity. Cohort study (prevalence); Level of evidence, 3. Our study evaluated 44 asymptomatic adolescent boys distributed in 2 groups of 22 rowers and 22 control subjects. All the examinations were performed using a 0.35-T open-field MRI unit and evaluated by 2 experienced radiologists blinded to the study groups. Each MRI scan was analyzed for the presence of disc degeneration/desiccation, herniated or bulging disc, pars interarticularis stress reaction, and spondylolysis. The Student t test and the Fisher exact test were used for statistical analyses. Nine rowers (40.9%) had at least 1 abnormality detected by MRI in the lumbar spine, whereas only 2 participants (9.1%) in the control group had at least 1 MRI abnormality (P = .03). Seven disc changes (31.8%) and 6 pars abnormalities (27.3%) were found in the group of elite rowers. In the control group, 3 disc changes (13.6%) and no pars abnormalities were found in the MR scans. The comparison between groups showed statistically significant differences in stress reaction of the pars articularis. Disc disease and pars interarticularis stress reaction are prevalent abnormalities of the lumbar spine of high-performance rowers.

Active Control of Fan Noise-Feasibility Study. Volume 2: Canceling Noise Source-Design of an Acoustic Plate Radiator Using Piezoceramic Actuators

NASA Technical Reports Server (NTRS)

Pla, F. G.; Rajiyah, H.

1995-01-01

The feasibility of using acoustic plate radiators powered by piezoceramic thin sheets as canceling sources for active control of aircraft engine fan noise is demonstrated. Analytical and numerical models of actuated beams and plates are developed and validated. An optimization study is performed to identify the optimum combination of design parameters that maximizes the plate volume velocity for a given resonance frequency. Fifteen plates with various plate and actuator sizes, thicknesses, and bonding layers were fabricated and tested using results from the optimization study. A maximum equivalent piston displacement of 0.39 mm was achieved with the optimized plate samples tested with only one actuator powered, corresponding to a plate deflection at the center of over 1 millimeter. This is very close to the deflection required for a full size engine application and represents a 160-fold improvement over previous work. Experimental results further show that performance is limited by the critical stress of the piezoceramic actuator and bonding layer rather than by the maximum moment available from the actuator. Design enhancements are described in detail that will lead to a flight-worthy acoustic plate radiator by minimizing actuator tensile stresses and reducing nonlinear effects. Finally, several adaptive tuning methods designed to increase the bandwidth of acoustic plate radiators are analyzed including passive, active, and semi-active approaches. The back chamber pressurization and volume variation methods are investigated experimentally and shown to be simple and effective ways to obtain substantial control over the resonance frequency of a plate radiator. This study shows that piezoceramic-based plate radiators can be a viable acoustic source for active control of aircraft engine fan noise.

Tunable Optical Filters Having Electro-optic Whispering-gallery-mode Resonators

NASA Technical Reports Server (NTRS)

Savchenkov, Anatoliy (Inventor); Ilchenko, Vladimir (Inventor); Matsko, Andrey B. (Inventor); Maleki, Lutfollah (Inventor)

2006-01-01

Tunable optical filters using whispering-gallery-mode (WGM) optical resonators are described. The WGM optical resonator in a filter exhibits an electro-optical effect and hence is tunable by applying a control electrical signal.

Quantum state transfer and controlled-phase gate on one-dimensional superconducting resonators assisted by a quantum bus.

PubMed

Hua, Ming; Tao, Ming-Jie; Deng, Fu-Guo

2016-02-24

We propose a quantum processor for the scalable quantum computation on microwave photons in distant one-dimensional superconducting resonators. It is composed of a common resonator R acting as a quantum bus and some distant resonators rj coupled to the bus in different positions assisted by superconducting quantum interferometer devices (SQUID), different from previous processors. R is coupled to one transmon qutrit, and the coupling strengths between rj and R can be fully tuned by the external flux through the SQUID. To show the processor can be used to achieve universal quantum computation effectively, we present a scheme to complete the high-fidelity quantum state transfer between two distant microwave-photon resonators and another one for the high-fidelity controlled-phase gate on them. By using the technique for catching and releasing the microwave photons from resonators, our processor may play an important role in quantum communication as well.

Single-photon routing with whispering-gallery resonators

NASA Astrophysics Data System (ADS)

Huang, Jin-Song; Zhang, Jia-Hao; Wei, L. F.

2018-04-01

Quantum routing of single photons in a system with two waveguides coupled to two whispering-gallery resonators (WGRs) are investigated theoretically. Using a real-space full quantum theory, photonic scattering amplitudes along four ports of the waveguide network are analytically obtained. It is shown that, by adjusting the geometric and physical parameters of the two-WGR configuration, the quantum routing properties of single photons along the present waveguide network can be controlled effectively. The routing capability from input waveguide to another one can significantly exceed 0.5 near the resonance point of scattering spectra, which can be achieved with only one resonator. By properly designing the distance between two WGRs and the waveguide-WGR coupling strengths, the transfer rate between the waveguides can also reach certain sufficiently high values even in the non-resonance regime. Moreover, Fano-like resonances in the scattering spectra are designable. The proposed system may provide a potential application in controlling single-photon quantum routing.

Integrated unaligned resonant modulator tuning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zortman, William A.; Lentine, Anthony L.

Methods and systems for tuning a resonant modulator are disclosed. One method includes receiving a carrier signal modulated by the resonant modulator with a stream of data having an approximately equal number of high and low bits, determining an average power of the modulated carrier signal, comparing the average power to a predetermined threshold, and operating a tuning device coupled to the resonant modulator based on the comparison of the average power and the predetermined threshold. One system includes an input structure, a plurality of processing elements, and a digital control element. The input structure is configured to receive, frommore » the resonant modulator, a modulated carrier signal. The plurality of processing elements are configured to determine an average power of the modulated carrier signal. The digital control element is configured to operate a tuning device coupled to the resonant modulator based on the average power of the modulated carrier signal.« less

A Randomized Case-Series Study Comparing the Stability of Implant with Two Different Surfaces Placed in Fresh Extraction Sockets and Immediately Loaded

PubMed Central

Vanden Bogaerde, Leonardo; Sennerby, Lars

2016-01-01

Background. Hydrophilic and moderately rough implant surfaces have been proposed to enhance the osseointegration response. Aim. The aim of this study was to compare early changes of stability for two implants with identical macrodesign but with different surface topographies. Materials and Methods. In 11 patients, a total of 22 implants (11 bimodal (minimally rough, control) and 11 proactive (moderately rough and hydrophilic, test), Neoss Ltd., Harrogate, UK) were immediately placed into fresh extraction sockets and immediately loaded. The peak insertion torque (IT) was measured in Ncm at placement. Resonance Frequency Analysis (RFA) measurements were made at baseline and 2, 4, 6, and 12 weeks after surgery. Results. The two implant types showed similar IT and RFA values at placement (NS). A dip of RFA values after 2 weeks followed by an increase was observed, where the test implant showed a less pronounced decrease and a more rapid recovery than the control implant. The test implants were significantly more stable than the control ones after 12 weeks. Conclusions. The results from the present study indicated that the hydrophilic and rougher test implant was more resistant to immediate loading and showed a significantly higher stability than the smoother control implant after 12 weeks. PMID:27042180

An Automatic Occlusion Device for Remote Control of Tumor Tissue Ischemia

PubMed Central

El-Dahdah, Hamid; Wang, Bei; He, Guanglong; Xu, Ronald X.

2015-01-01

We developed an automatic occlusion device for remote control of tumor tissue ischemia. The device consists of a flexible cannula encasing a shape memory alloy wire with its distal end connected to surgical suture. Regional tissue occlusion was tested on both the benchtop and the animal models. In the benchtop test, the occlusion device introduced quantitative and reproducible changes of blood flow in a tissue simulating phantom embedding a vessel simulator. In the animal test, the device generated a cyclic pattern of reversible ischemia in the right hinder leg tissue of a black male C57BL/6 mouse. We also developed a multimodal detector that integrates near infrared spectroscopy and electron paramagnetic resonance spectroscopy for continuous monitoring of tumor tissue oxygenation, blood content, and oxygen tension changes. The multimodal detector was tested on a cancer xenograft nude mouse undergoing reversible tumor ischemia. The automatic occlusion device and the multi-modal detector can be potentially integrated for closed-loop feedback control of tumor tissue ischemia. Such an integrated occlusion device may be used in multiple clinical applications such as regional hypoperfusion control in tumor resection surgeries and thermal ablation processes. In addition, the proposed occlusion device can also be used as a research tool to understand tumor oxygen transport and hemodynamic characteristics. PMID:20082532

Modular high-voltage bias generator powered by dual-looped self-adaptive wireless power transmission.

PubMed

Xie, Kai; Huang, An-Feng; Li, Xiao-Ping; Guo, Shi-Zhong; Zhang, Han-Lu

2015-04-01

We proposed a modular high-voltage (HV) bias generator powered by a novel transmitter-sharing inductive coupled wireless power transmission technology, aimed to extend the generator's flexibility and configurability. To solve the problems caused through an uncertain number of modules, a dual-looped self-adaptive control method is proposed that is capable of tracking resonance frequency while maintaining a relatively stable induction voltage for each HV module. The method combines a phase-locked loop and a current feedback loop, which ensures an accurate resonance state and a relatively constant boost ratio for each module, simplifying the architecture of the boost stage and improving the total efficiency. The prototype was built and tested. The input voltage drop of each module is less than 14% if the module number varies from 3 to 10; resonance tracking is completed within 60 ms. The efficiency of the coupling structure reaches up to 95%, whereas the total efficiency approaches 73% for a rated output. Furthermore, this technology can be used in various multi-load wireless power supply applications.

Structural biomechanics determine spectral purity of bush-cricket calls.

PubMed

Chivers, Benedict D; Jonsson, Thorin; Soulsbury, Carl D; Montealegre-Z, Fernando

2017-11-01

Bush-crickets (Orthoptera: Tettigoniidae) generate sound using tegminal stridulation. Signalling effectiveness is affected by the widely varying acoustic parameters of temporal pattern, frequency and spectral purity (tonality). During stridulation, frequency multiplication occurs as a scraper on one wing scrapes across a file of sclerotized teeth on the other. The frequency with which these tooth-scraper interactions occur, along with radiating wing cell resonant properties, dictates both frequency and tonality in the call. Bush-cricket species produce calls ranging from resonant, tonal calls through to non-resonant, broadband signals. The differences are believed to result from differences in file tooth arrangement and wing radiators, but a systematic test of the structural causes of broadband or tonal calls is lacking. Using phylogenetically controlled structural equation models, we show that parameters of file tooth density and file length are the best-fitting predictors of tonality across 40 bush-cricket species. Features of file morphology constrain the production of spectrally pure signals, but systematic distribution of teeth alone does not explain pure-tone sound production in this family. © 2017 The Authors.

Structural biomechanics determine spectral purity of bush-cricket calls

PubMed Central

2017-01-01

Bush-crickets (Orthoptera: Tettigoniidae) generate sound using tegminal stridulation. Signalling effectiveness is affected by the widely varying acoustic parameters of temporal pattern, frequency and spectral purity (tonality). During stridulation, frequency multiplication occurs as a scraper on one wing scrapes across a file of sclerotized teeth on the other. The frequency with which these tooth–scraper interactions occur, along with radiating wing cell resonant properties, dictates both frequency and tonality in the call. Bush-cricket species produce calls ranging from resonant, tonal calls through to non-resonant, broadband signals. The differences are believed to result from differences in file tooth arrangement and wing radiators, but a systematic test of the structural causes of broadband or tonal calls is lacking. Using phylogenetically controlled structural equation models, we show that parameters of file tooth density and file length are the best-fitting predictors of tonality across 40 bush-cricket species. Features of file morphology constrain the production of spectrally pure signals, but systematic distribution of teeth alone does not explain pure-tone sound production in this family. PMID:29187608

Adaptive synchronized switch damping on an inductor: a self-tuning switching law

NASA Astrophysics Data System (ADS)

Kelley, Christopher R.; Kauffman, Jeffrey L.

2017-03-01

Synchronized switch damping (SSD) techniques exploit low-power switching between passive circuits connected to piezoelectric material to reduce structural vibration. In the classical implementation of SSD, the piezoelectric material remains in an open circuit for the majority of the vibration cycle and switches briefly to a shunt circuit at every displacement extremum. Recent research indicates that this switch timing is only optimal for excitation exactly at resonance and points to more general optimal switch criteria based on the phase of the displacement and the system parameters. This work proposes a self-tuning approach that implements the more general optimal switch timing for synchronized switch damping on an inductor (SSDI) without needing any knowledge of the system parameters. The law involves a gradient-based search optimization that is robust to noise and uncertainties in the system. Testing of a physical implementation confirms this law successfully adapts to the frequency and parameters of the system. Overall, the adaptive SSDI controller provides better off-resonance steady-state vibration reduction than classical SSDI while matching performance at resonance.

Modeling and Simulation of a Parametrically Resonant Micromirror With Duty-Cycled Excitation.

PubMed

Shahid, Wajiha; Qiu, Zhen; Duan, Xiyu; Li, Haijun; Wang, Thomas D; Oldham, Kenn R

2014-12-01

High frequency large scanning angle electrostatically actuated microelectromechanical systems (MEMS) mirrors are used in a variety of applications involving fast optical scanning. A 1-D parametrically resonant torsional micromirror for use in biomedical imaging is analyzed here with respect to operation by duty-cycled square waves. Duty-cycled square wave excitation can have significant advantages for practical mirror regulation and/or control. The mirror's nonlinear dynamics under such excitation is analyzed in a Hill's equation form. This form is used to predict stability regions (the voltage-frequency relationship) of parametric resonance behavior over large scanning angles using iterative approximations for nonlinear capacitance behavior of the mirror. Numerical simulations are also performed to obtain the mirror's frequency response over several voltages for various duty cycles. Frequency sweeps, stability results, and duty cycle trends from both analytical and simulation methods are compared with experimental results. Both analytical models and simulations show good agreement with experimental results over the range of duty cycled excitations tested. This paper discusses the implications of changing amplitude and phase with duty cycle for robust open-loop operation and future closed-loop operating strategies.

Nanonewton thrust measurement of photon pressure propulsion using semiconductor laser

NASA Astrophysics Data System (ADS)

Iwami, K.; Akazawa, Taku; Ohtsuka, Tomohiro; Nishida, Hiroyuki; Umeda, Norihiro

2011-09-01

To evaluate the thrust produced by photon pressure emitted from a 100 W class continuous-wave semiconductor laser, a torsion-balance precise thrust stand is designed and tested. Photon emission propulsion using semiconductor light sources attract interests as a possible candidate for deep-space propellant-less propulsion and attitude control system. However, the thrust produced by photon emission as large as several ten nanonewtons requires precise thrust stand. A resonant method is adopted to enhance the sensitivity of the biflier torsional-spring thrust stand. The torsional spring constant and the resonant of the stand is 1.245 × 10-3 Nm/rad and 0.118 Hz, respectively. The experimental results showed good agreement with the theoretical estimation. The thrust efficiency for photon propulsion was also defined. A maximum thrust of 499 nN was produced by the laser with 208 W input power (75 W of optical output) corresponding to a thrust efficiency of 36.7%. The minimum detectable thrust of the stand was estimated to be 2.62 nN under oscillation at a frequency close to resonance.

Aberration compensation in a Skew parametric-resonance ionization cooling channel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sy, Amy V.; Derbenev, Yaroslav S.; Morozov, Vasiliy

Skew Parametric-resonance Ionization Cooling (Skew PIC) represents a novel method for focusing of highly divergent particle beams, as in the final 6D cooling stage of a high-luminosity muon collider. In the muon collider concept, the resultant equilibrium transverse emittances from cooling with Skew PIC are an order of magnitude smaller than in conventional ionization cooling. The concept makes use of coupling of the transverse dynamic behavior, and the linear dynamics are well-behaved with good agreement between analytic solutions and simulation results. Compared to the uncoupled system, coupling of the transverse dynamic behavior purports to reduce the number of multipoles requiredmore » for aberration compensation while also avoiding unwanted resonances. Aberration compensation is more complicated in the coupled case, especially in the high-luminosity muon collider application where equilibrium angular spreads in the cooling channel are on the order of 200 mrad. We present recent progress on aberration compensation for control of highly divergent muon beams in the coupled correlated optics channel, and a simple cooling model to test the transverse acceptance of the channel.« less

The design of a small linear-resonant, split Stirling cryogenic refrigerator compressor

NASA Technical Reports Server (NTRS)

Ackermann, R. A.

1985-01-01

The development of a small linear-resonant compressor for use in a 1/4-watt, 78K, split Stirling cryogenic refrigerator is discussed. The compressor contains the following special features: (1) a permanent-magnet linear motor; (2) resonant dynamics; (3) dynamic balancing; and (4) a close-clearance seal between the compressor piston and cylinder. This paper describes the design of the compressor, and presents component test data and system test data for the compressor driving a 1/4-watt expander.

Screech tones from free and ducted supersonic jets

NASA Technical Reports Server (NTRS)

Tam, C. K. W.; Ahuja, K. K.; Jones, R. R., III

1994-01-01

It is well known that screech tones from supersonic jets are generated by a feedback loop. The loop consists of three main components. They are the downstream propagating instability wave, the shock cell structure in the jet plume, and the feedback acoustic waves immediately outside the jet. Evidence will be presented to show that the screech frequency is largely controlled by the characteristics of the feedback acoustic waves. The feedback loop is driven by the instability wave of the jet. Thus the tone intensity and its occurrence are dictated by the characteristics of the instability wave. In this paper the dependence of the instability wave spectrum on the azimuthal mode number (axisymmetric or helical/flapping mode, etc.), the jet-to-ambient gas temperature ratio, and the jet Mach number are studied. The results of this study provide an explanation for the observed screech tone mode switch phenomenon (changing from axisymmetric to helical mode as Mach number increases) and the often-cited experimental observation that tone intensity reduces with increase in jet temperature. For ducted supersonic jets screech tones can also be generated by feedback loops formed by the coupling of normal duct modes to instability waves of the jet. The screech frequencies are dictated by the frequencies of the duct modes. Super resonance, resonance involving very large pressure oscillations, can occur when the feedback loop is powered by the most amplified instability wave. It is proposed that the observed large amplitude pressure fluctuations and tone in the test cells of Arnold Engineering Development Center were generated by super resonance. Estimated super-resonance frequency for a Mach 1.3 axisymmetric jet tested in the facility agrees well with measurement.

Performance of a High-Fidelity 4kW-Class Engineering Model PPU and Integration with HiVHAc System

NASA Technical Reports Server (NTRS)

Pinero, Luis R.; Kamhawi, Hani; Shilo, Vlad

2016-01-01

The High Voltage Hall Accelerator (HiVHAc) propulsion system consists of a thruster, power processing unit (PPU), and propellant feed system. An engineering model PPU was developed by Colorado Power Electronics, Inc. funded by NASA's Small Business Innovative Research Program. This PPU uses an innovative 3-phase resonant converter to deliver 4 kW of discharge power over a wide range of input and output voltage conditions. The PPU includes a digital control interface unit that automatically controls the PPU and a xenon flow control module (XFCM). It interfaces with a control computer to receive highlevel commands and relay telemetry through a MIL-STD-1553B interface. The EM PPU was thoroughly tested at GRC for functionality and performance at temperature limits and demonstrated total efficiencies a high as 95 percent. Integrated testing of the unit was performed with the HiVHAc thruster and the XFCM to demonstrate closed-loop control of discharge current with anode flow. Initiation of the main discharge and power throttling were also successfully demonstrated and discharge oscillations were characterized.

Proceedings of the 2nd Experimental Chaos Conference

NASA Astrophysics Data System (ADS)

Ditto, William; Pecora, Lou; Shlesinger, Michael; Spano, Mark; Vohra, Sandeep

1995-02-01

The Table of Contents for the full book PDF is as follows: * Introduction * Spatiotemporal Phenomena * Experimental Studies of Chaotic Mixing * Using Random Maps in the Analysis of Experimental Fluid Flows * Transition to Spatiotemporal Chaos in a Reaction-Diffusion System * Ion-Dynamical Chaos in Plasmas * Optics * Chaos in a Synchronously Driven Optical Resonator * Chaos, Patterns and Defects in Stimulated Scattering Phenomena * Test of the Normal Form for a Subcritical Bifurcation * Observation of Bifurcations and Chaos in a Driven Fiber Optic Coil * Applications -- Communications * Robustness and Signal Recovery in a Synchronized Chaotic System * Synchronizing Nonautonomous Chaotic Circuits * Synchronization of Pulse-Coupled Chaotic Oscillators * Ocean Transmission Effects on Chaotic Signals * Controlling Symbolic Dynamics for Communication * Applications -- Control * Analysis of Nonlinear Actuators Using Chaotic Waveforms * Controlling Chaos in a Quasiperiodic Electronic System * Control of Chaos in a CO2 Laser * General Research * Video-Based Analysis of Bifurcation Phenomena in Radio-Frequency-Excited Inert Gas Plasmas * Transition from Soliton to Chaotic Motion During the Impact of a Nonlinear Structure * Sonoluminescence in a Single Bubble: Periodic, Quasiperiodic and Chaotic Light Source * Quantum Chaos Experiments Using Microwave Cavities * Experiments on Quantum Chaos With and Without Time Reversibility * When Small Noise Imposed on Deterministic Dynamics Becomes Important * Biology * Chaos Control for Cardiac Arrhythmias * Irregularities in Spike Trains of Cat Retinal Ganglion Cells * Broad-Band Synchronization in Monkey Neocortex * Applicability of Correlation Dimension Calculations to Blood Pressure Signal in Rats * Tests for Deterministic Chaos in Noisy Time Series * The Crayfish Mechanoreceptor Cell: A Biological Example of Stochastic Resonance * Chemistry * Chaos During Heterogeneous Chemical Reactions * Stabilizing and Tracking Unstable Periodic Orbits and Stationary States in Chemical Systems * Recursive Proportional-Feedback and Its Use to Control Chaos in an Electrochemical System * Temperature Patterns on Catalytic Surfaces * Meteorology/Oceanography * Nonlinear Evolution of Water Waves: Hilbert's View * Fractal Properties of Isoconcentration Surfaces in a Smoke Plume * Fractal Dimensions of Remotely Sensed Atmospheric Signals * Are Ocean Surface Waves Chaotic? * Dynamical Attractor Reconstruction for a Marine Stratocumulus Cloud

Detection and quantification of creep strain using process compensated resonance testing (PCRT) sorting modules trained with modeled resonance spectra

NASA Astrophysics Data System (ADS)

Heffernan, Julieanne; Biedermann, Eric; Mayes, Alexander; Livings, Richard; Jauriqui, Leanne; Goodlet, Brent; Aldrin, John C.; Mazdiyasni, Siamack

2018-04-01

Process Compensated Resonant Testing (PCRT) is a full-body nondestructive testing (NDT) method that measures the resonance frequencies of a part and correlates them to the part's material and/or damage state. PCRT testing is used in the automotive, aerospace, and power generation industries via automated PASS/FAIL inspections to distinguish parts with nominal process variation from those with the defect(s) of interest. Traditional PCRT tests are created through the statistical analysis of populations of "good" and "bad" parts. However, gathering a statistically significant number of parts can be costly and time-consuming, and the availability of defective parts may be limited. This work uses virtual databases of good and bad parts to create two targeted PCRT inspections for single crystal (SX) nickel-based superalloy turbine blades. Using finite element (FE) models, populations were modeled to include variations in geometric dimensions, material properties, crystallographic orientation, and creep damage. Model results were verified by comparing the frequency variation in the modeled populations with the measured frequency variations of several physical blade populations. Additionally, creep modeling results were verified through the experimental evaluation of coupon geometries. A virtual database of resonance spectra was created from the model data. The virtual database was used to create PCRT inspections to detect crystallographic defects and creep strain. Quantification of creep strain values using the PCRT inspection results was also demonstrated.

Development of low cost and accurate homemade sensor system based on Surface Plasmon Resonance (SPR)

NASA Astrophysics Data System (ADS)

Laksono, F. D.; Supardianningsih; Arifin, M.; Abraha, K.

2018-04-01

In this paper, we developed homemade and computerized sensor system based on Surface Plasmon Resonance (SPR). The developed systems consist of mechanical system instrument, laser power sensor, and user interface. The mechanical system development that uses anti-backlash gear design was successfully able to enhance the angular resolution angle of incidence laser up to 0.01°. In this system, the laser detector acquisition system and stepper motor controller utilizing Arduino Uno which is easy to program, flexible, and low cost, was used. Furthermore, we employed LabView’s user interface as the virtual instrument for facilitating the sample measurement and for transforming the data recording directly into the digital form. The test results using gold-deposited half-cylinder prism showed the Total Internal Reflection (TIR) angle of 41,34°± 0,01° and SPR angle of 44,20°± 0,01°, respectively. The result demonstrated that the developed system managed to reduce the measurement duration and data recording errors caused by human error. Also, the test results also concluded that the system’s measurement is repeatable and accurate.

Design and Verification of a Digital Controller for a 2-Piece Hemispherical Resonator Gyroscope.

PubMed

Lee, Jungshin; Yun, Sung Wook; Rhim, Jaewook

2016-04-20

A Hemispherical Resonator Gyro (HRG) is the Coriolis Vibratory Gyro (CVG) that measures rotation angle or angular velocity using Coriolis force acting the vibrating mass. A HRG can be used as a rate gyro or integrating gyro without structural modification by simply changing the control scheme. In this paper, differential control algorithms are designed for a 2-piece HRG. To design a precision controller, the electromechanical modelling and signal processing must be pre-performed accurately. Therefore, the equations of motion for the HRG resonator with switched harmonic excitations are derived with the Duhamel Integral method. Electromechanical modeling of the resonator, electric module and charge amplifier is performed by considering the mode shape of a thin hemispherical shell. Further, signal processing and control algorithms are designed. The multi-flexing scheme of sensing, driving cycles and x, y-axis switching cycles is appropriate for high precision and low maneuverability systems. The differential control scheme is easily capable of rejecting the common mode errors of x, y-axis signals and changing the rate integrating mode on basis of these studies. In the rate gyro mode the controller is composed of Phase-Locked Loop (PLL), amplitude, quadrature and rate control loop. All controllers are designed on basis of a digital PI controller. The signal processing and control algorithms are verified through Matlab/Simulink simulations. Finally, a FPGA and DSP board with these algorithms is verified through experiments.

Non-resonant Nanoscale Extreme Light Confinement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Subramania, Ganapathi Subramanian; Huber, Dale L.

2014-09-01

A wide spectrum of photonics activities Sandia is engaged in such as solid state lighting, photovoltaics, infrared imaging and sensing, quantum sources, rely on nanoscale or ultrasubwavelength light-matter interactions (LMI). The fundamental understanding in confining electromagnetic power and enhancing electric fields into ever smaller volumes is key to creating next generation devices for these programs. The prevailing view is that a resonant interaction (e.g. in microcavities or surface-plasmon polaritions) is necessary to achieve the necessary light confinement for absorption or emission enhancement. Here we propose new paradigm that is non-resonant and therefore broadband and can achieve light confinement and fieldmore » enhancement in extremely small areas [~(λ/500)^2 ]. The proposal is based on a theoretical work[1] performed at Sandia. The paradigm structure consists of a periodic arrangement of connected small and large rectangular slits etched into a metal film named double-groove (DG) structure. The degree of electric field enhancement and power confinement can be controlled by the geometry of the structure. The key operational principle is attributed to quasistatic response of the metal electrons to the incoming electromagnetic field that enables non-resonant broadband behavior. For this exploratory LDRD we have fabricated some test double groove structures to enable verification of quasistatic electronic response in the mid IR through IR optical spectroscopy. We have addressed some processing challenges in DG structure fabrication to enable future design of complex sensor and detector geometries that can utilize its non-resonant field enhancement capabilities.].« less

Digital Platform for Wafer-Level MEMS Testing and Characterization Using Electrical Response

PubMed Central

Brito, Nuno; Ferreira, Carlos; Alves, Filipe; Cabral, Jorge; Gaspar, João; Monteiro, João; Rocha, Luís

2016-01-01

The uniqueness of microelectromechanical system (MEMS) devices, with their multiphysics characteristics, presents some limitations to the borrowed test methods from traditional integrated circuits (IC) manufacturing. Although some improvements have been performed, this specific area still lags behind when compared to the design and manufacturing competencies developed over the last decades by the IC industry. A complete digital solution for fast testing and characterization of inertial sensors with built-in actuation mechanisms is presented in this paper, with a fast, full-wafer test as a leading ambition. The full electrical approach and flexibility of modern hardware design technologies allow a fast adaptation for other physical domains with minimum effort. The digital system encloses a processor and the tailored signal acquisition, processing, control, and actuation hardware control modules, capable of the structure position and response analysis when subjected to controlled actuation signals in real time. The hardware performance, together with the simplicity of the sequential programming on a processor, results in a flexible and powerful tool to evaluate the newest and fastest control algorithms. The system enables measurement of resonant frequency (Fr), quality factor (Q), and pull-in voltage (Vpi) within 1.5 s with repeatability better than 5 ppt (parts per thousand). A full-wafer with 420 devices under test (DUTs) has been evaluated detecting the faulty devices and providing important design specification feedback to the designers. PMID:27657087

Digital Platform for Wafer-Level MEMS Testing and Characterization Using Electrical Response.

PubMed

Brito, Nuno; Ferreira, Carlos; Alves, Filipe; Cabral, Jorge; Gaspar, João; Monteiro, João; Rocha, Luís

2016-09-21

The uniqueness of microelectromechanical system (MEMS) devices, with their multiphysics characteristics, presents some limitations to the borrowed test methods from traditional integrated circuits (IC) manufacturing. Although some improvements have been performed, this specific area still lags behind when compared to the design and manufacturing competencies developed over the last decades by the IC industry. A complete digital solution for fast testing and characterization of inertial sensors with built-in actuation mechanisms is presented in this paper, with a fast, full-wafer test as a leading ambition. The full electrical approach and flexibility of modern hardware design technologies allow a fast adaptation for other physical domains with minimum effort. The digital system encloses a processor and the tailored signal acquisition, processing, control, and actuation hardware control modules, capable of the structure position and response analysis when subjected to controlled actuation signals in real time. The hardware performance, together with the simplicity of the sequential programming on a processor, results in a flexible and powerful tool to evaluate the newest and fastest control algorithms. The system enables measurement of resonant frequency (Fr), quality factor (Q), and pull-in voltage (Vpi) within 1.5 s with repeatability better than 5 ppt (parts per thousand). A full-wafer with 420 devices under test (DUTs) has been evaluated detecting the faulty devices and providing important design specification feedback to the designers.

Investigation of space stable thermal control coating properties

NASA Technical Reports Server (NTRS)

Mookherji, T.

1971-01-01

A capability to study the nuclear magnetic resonance of spacecraft thermal control coating has been built utilizing an electromagnet and V-series and Wl-series electronics. The electronics associated with the electromagnet had to be modified to make it compatible with the resonance measuring system. Resonance measurements have been performed on ZnO, Zn2TiO4 and FEP Teflon. The failure to observe resonance in ZnO and Zn2TiO4 has been theoretically explained. The linewidth and second moment measurements on ultraviolet irradiated FEP Teflon showed that there was no measurable degradation of the material due to short term irradiation.

Control of integrated micro-resonator wavelength via balanced homodyne locking.

PubMed

Cox, Jonathan A; Lentine, Anthony L; Trotter, Douglas C; Starbuck, Andrew L

2014-05-05

We describe and experimentally demonstrate a method for active control of resonant modulators and filters in an integrated photonics platform. Variations in resonance frequency due to manufacturing processes and thermal fluctuations are corrected by way of balanced homodyne locking. The method is compact, insensitive to intensity fluctuations, minimally disturbs the micro-resonator, and does not require an arbitrary reference to lock. We demonstrate long-term stable locking of an integrated filter to a laser swept over 1.25 THz. In addition, we show locking of a modulator with low bit error rate while the chip temperature is varied from 5 to 60° C.

Self-Other Resonance, Its Control and Prosocial Inclinations: Brain-Behavior Relationships

PubMed Central

Christov-Moore, Leonardo; Iacoboni, Marco

2016-01-01

Humans seem to place a positive reward value on prosocial behavior. Evidence suggests that this prosocial inclination is driven by our reflexive tendency to share in the observed sensations, emotions and behavior of others, or “self-other resonance”. In this study, we examine how neural correlates of self-other resonance relate to prosocial decision-making. Subjects performed two tasks while undergoing fMRI: Observation of a human hand pierced by a needle, and observation and imitation of emotional facial expressions. Outside the scanner, subjects played the Dictator Game with players of low or high income (represented by neutral-expression headshots). Subjects’ offers in the Dictator Game were correlated with activity in neural systems associated with self-other resonance and anticorrelated with activity in systems implicated in the control of pain, affect and imitation. Activity in these latter systems was specifically correlated with subjects’ diminished sharing towards players of high incomes. Functional connectivity between areas involved in self-other resonance and top-down control was negatively correlated with subjects’ offers. This study suggests that the interaction between self-other resonance and top-down control processes are an important component of prosocial inclinations towards others, even when biological stimuli associated with self-other resonance are limited. These findings support a view of prosocial decision-making that is grounded in embodied cognition. PMID:26954937

Active Tuning of Spontaneous Emission by Mie-Resonant Dielectric Metasurfaces.

PubMed

Bohn, Justus; Bucher, Tobias; Chong, Katie E; Komar, Andrei; Choi, Duk-Yong; Neshev, Dragomir N; Kivshar, Yuri S; Pertsch, Thomas; Staude, Isabelle

2018-06-13

Mie-resonant dielectric metasurfaces offer comprehensive opportunities for the manipulation of light fields with high efficiency. Additionally, various strategies for the dynamic tuning of the optical response of such metasurfaces were demonstrated, making them important candidates for reconfigurable optical devices. However, dynamic control of the light-emission properties of active Mie-resonant dielectric metasurfaces by an external control parameter has not been demonstrated so far. Here, we experimentally demonstrate the dynamic tuning of spontaneous emission from a Mie-resonant dielectric metasurface that is situated on a fluorescent substrate and embedded into a liquid crystal cell. By switching the liquid crystal from the nematic state to the isotropic state via control of the cell temperature, we induce a shift of the spectral position of the metasurface resonances. This results in a change of the local photonic density of states, which, in turn, governs the enhancement of spontaneous emission from the substrate. Specifically, we observe spectral tuning of both the electric and magnetic dipole resonances, resulting in a 2-fold increase of the emission intensity at λ ≈ 900 nm. Our results demonstrate a viable strategy to realize flat tunable light sources based on dielectric metasurfaces.

Linear frequency tuning in an LC-resonant system using a C-V response controllable MEMS varactor

NASA Astrophysics Data System (ADS)

Han, Chang-Hoon; Yoon, Yong-Hoon; Ko, Seung-Deok; Seo, Min-Ho; Yoon, Jun-Bo

2017-12-01

This paper proposes a device level solution to achieve linear frequency tuning with respect to a tuning voltage ( V tune ) sweep in an inductor ( L)-capacitor ( C) resonant system. Since the linearity of the resonant frequency vs. tuning voltage ( f- V) relationship in an LC-resonant system is closely related to the C- V response characteristic of the varactor, we propose a C- V response tunable varactor to realize the linear frequency tuning. The proposed varactor was fabricated using microelectromechanical system (MEMS) surface micromachining. The fabricated MEMS varactor has the ability to dynamically change the C- V response characteristic according to a curve control voltage ( V curve- control ). When V curve- control was increased from zero to 9 V, the C- V response curve was changed from a linear to a concave form (i.e., the capacitance decreased quickly in the low tuning voltage region and slowly in the high tuning voltage region). This change in the C- V response characteristic resulted in a change in the f- V relationship, and we successfully demonstrated almost perfectly linear frequency tuning in the LC-resonant system, with a linearity factor of 99.95%.

Post-fabrication voltage controlled resonance tuning of nanoscale plasmonic antennas.

PubMed

Lumdee, Chatdanai; Toroghi, Seyfollah; Kik, Pieter G

2012-07-24

Voltage controlled wavelength tuning of the localized surface plasmon resonance of gold nanoparticles on an aluminum film is demonstrated in single particle microscopy and spectroscopy measurements. Anodization of the Al film after nanoparticle deposition forms an aluminum oxide spacer layer between the gold particles and the Al film, modifying the particle-substrate interaction. Darkfield microscopy reveals ring-shaped scattering images from individual Au nanoparticles, indicative of plasmon resonances with a dipole moment normal to the substrate. Single particle scattering spectra show narrow plasmon resonances that can be tuned from ~580 to ~550 nm as the anodization voltage increases to 12 V. All observed experimental trends could be reproduced in numerical simulations. The presented approach could be used as a general postfabrication resonance optimization step of plasmonic nanoantennas and devices.

The Effect of Postmastectomy Radiation Therapy on Breast Implants: Material Analysis on Silicone and Polyurethane Prosthesis.

PubMed

Lo Torto, Federico; Relucenti, Michela; Familiari, Giuseppe; Vaia, Nicola; Casella, Donato; Matassa, Roberto; Miglietta, Selenia; Marinozzi, Franco; Bini, Fabiano; Fratoddi, Ilaria; Sciubba, Fabio; Cassese, Raffaele; Tombolini, Vincenzo; Ribuffo, Diego

2018-05-17

The pathogenic mechanism underlying capsular contracture is still unknown. It is certainly a multifactorial process, resulting from human body reaction, biofilm activation, bacteremic seeding, or silicone exposure. The scope of the present article is to investigate the effect of hypofractionated radiotherapy protocol (2.66 Gy × 16 sessions) both on silicone and polyurethane breast implants. Silicone implants and polyurethane underwent irradiation according to a hypofractionated radiotherapy protocol for the treatment of breast cancer. After irradiation implant shells underwent mechanical, chemical, and microstructural evaluation by means of tensile testing, infrared spectra in attenuated total reflectance mode, nuclear magnetic resonance, and field emission scanning electron microscopy. At superficial analysis, irradiated silicone samples show several visible secondary and tertiary blebs. Polyurethane implants showed an open cell structure, which closely resembles a sponge. Morphological observation of struts from treated polyurethane sample shows a more compact structure, with significantly shorter and thicker struts compared with untreated sample. The infrared spectra in attenuated total reflectance mode spectra of irradiated and control samples were compared either for silicon and polyurethane samples. In the case of silicone-based membranes, treated and control specimens showed similar bands, with little differences in the treated one. Nuclear magnetic resonance spectra on the fraction soluble in CDCl3 support these observations. Tensile tests on silicone samples showed a softer behavior of the treated ones. Tensile tests on Polyurethane samples showed no significant differences. Polyurethane implants seem to be more resistant to radiotherapy damage, whereas silicone prosthesis showed more structural, mechanical, and chemical modifications.

Fluid Sloshing Characteristics in Spacecraft Propellant Tanks with Diaphragms

NASA Technical Reports Server (NTRS)

Green, Steve; Burkey, Russell; Viana, Flavia; Sudermann, James

2007-01-01

All spacecraft are launched from the Earth as payloads on a launch vehicle. During portions of the launch profile, the spacecraft could be subjected to nearly purely translational oscillatory lateral motions as the launch vehicle control system guides the rocket along its flight path. All partially-filled liquids tanks, even those with diaphragms, exhibit sloshing behavior under these conditions and some tanks can place large loads on their support structures if the sloshing is in resonance with the control system oscillation frequency. The objectives of this project were to conduct experiments using a full-scale model of a flight tank to 1) determine whether launch vehicle vibrations can cause the diaphragm to achieve a repeatable configuration, regardless of initial condition, and 2) identify the slosh characteristics of the propellant tank under flight-like lateral motions for different diaphragm shapes and vibration levels. The test results show that 1) the diaphragm shape is not affected by launch vibrations, and 2) the resonance-like behavior of the fluid and diaphragm is strongly affected by the nonlinear stiffness and damping provided by the diaphragm.

Phase collapse and revival of a 1-mode Bose-Einstein condensate induced by an off-resonant optical probe field and superselection rules

NASA Astrophysics Data System (ADS)

Arruda, L. G. E.; Prataviera, G. A.; de Oliveira, M. C.

2018-02-01

Phase collapse and revival for Bose-Einstein condensates are nonlinear phenomena appearing due to atomic collisions. While it has been observed in a general setting involving many modes, for one-mode condensates its occurrence is forbidden by the particle number superselection rule (SSR), which arises because there is no phase reference available. We consider a single mode atomic Bose-Einstein condensate interacting with an off-resonant optical probe field. We show that the condensate phase revival time is dependent on the atom-light interaction, allowing optical control on the atomic collapse and revival dynamics. Incoherent effects over the condensate phase are included by considering a continuous photo-detection over the probe field. We consider conditioned and unconditioned photo-counting events and verify that no extra control upon the condensate is achieved by the probe photo-detection, while further inference of the atomic system statistics is allowed leading to a useful test of the SSR on particle number and its imposition on the kind of physical condensate state.

[Follow-up of resting-state brain function with magnetic resonance imaging in patients with type 2 diabetes mellitus].

PubMed

Qi, N; Cui, Y; Liu, J C; Yu, M; Teng, G J

2017-10-24

Objective: To investigate the changes of resting brain function with time in patients with type 2 diabetes mellitus (T2DM) by using regional homogeneity (ReHo) with resting-state functional magnetic resonance imaging (rs-fMRI). Methods: Multidimensional cognitive function tests and rs-fMRI scans were performed in 21 T2DM patients and 12 healthy controls in 2012 and 2015 respectively.The differences in clinical variables and the ReHo values before and after were measured by paired sample t test, and the correlation between the change of ReHo value and the change of clinical variables was measured by Pearson correlation analysis based on voxel. Results: The delayed score (14±6) of the T2DM patients in 2015 was significantly lower than that in 2012 (18±6) ( t =-2.88, P =0.009); while the value of ReHo in the bilateral occipital lobe and right middle frontal gyrus was significantly lower than that in 2012 ( P <0.01, Alphasim correction). And the decreased ReHo value in the left occipital lobe was significantly correlated with the change of complex figure test (CFT) delay score and the trail making test-B (TMT-B)( r =0.52, -0.46, both P <0.05). No significant change in cognitive function tests in the healthy control group was found between the two years, ReHo value in right cuneus decreased significantly ( P <0.01, Alphasim correction), but it increased significantly in superior frontal gyrus ( P <0.01, Alphasim correction) in 2015.No significant correlation between the changes of the ReHo values in the right cuneus and right superior frontal gyrus and the changes of cognitive function scores was found in the healthy controls. Conclusions: The visual memory is significantly declined in T2DM patients within 3 years.The reduced neural activity areas in T2DM patients are in the bilateral occipitai lobes and the right middle frontal lobe. Decreased neural activity in the left occipital area is related to visual impairment, information processing speed and attention drops.

Metasurface Mirrors for External Control of Mie Resonances.

PubMed

van de Groep, Jorik; Brongersma, Mark L

2018-06-13

The ability to control and structurally tune the optical resonances of semiconductor nanostructures has far-reaching implications for a wide range of optical applications, including photodetectors, (bio)sensors, and photovoltaics. Such control is commonly obtained by tailoring the nanostructure's geometry, material, or dielectric environment. Here, we combine insights from the field of coherent optics and metasurface mirrors to effectively turn Mie resonances on and off with high spatial control and in a polarization-dependent fashion. We illustrate this in an integrated device by manipulating the photocurrent spectra of a single-nanowire photodetector placed on a metasurface mirror. This approach can be generalized to control spectral, angle-dependent, absorption, and scattering properties of semiconductor nanostructures with an engineered metasurface and without a need to alter their geometric or materials properties.

System for controlled acoustic rotation of objects

NASA Technical Reports Server (NTRS)

Barmatz, M. B. (Inventor)

1983-01-01

A system is described for use with acoustically levitated objects, which enables close control of rotation of the object. One system includes transducers that propagate acoustic waves along the three dimensions (X, Y, Z) of a chamber of rectangular cross section. Each transducers generates one wave which is resonant to a corresponding chamber dimension to acoustically levitate an object, and additional higher frequency resonant wavelengths for controlling rotation of the object. The three chamber dimensions and the corresponding three levitation modes (resonant wavelengths) are all different, to avoid degeneracy, or interference, of waves with one another, that could have an effect on object rotation. Only the higher frequencies, with pairs of them having the same wavelength, are utilized to control rotation, so that rotation is controlled independently of levitation and about any arbitrarily chosen axis.

Status of the PHOENIX electron cyclotron resonance charge breeder at ISOLDE, CERN.

PubMed

Barton, Charles; Cederkall, Joakim; Delahaye, Pierre; Kester, Oliver; Lamy, Thierry; Marie-Jeanne, Mélanie

2008-02-01

We report here on the last progresses made with the PHOENIX electron cyclotron resonance charge breeder test bench at ISOLDE. Recently, an experiment was performed to test the trapping of (61)Fe daughter nuclides from the decay of (61)Mn nuclides. Preliminary results are given.

Posterior Insular Molecular Changes in Myofascial Pain

PubMed Central

Gerstner, G.E.; Gracely, R.H.; Deebajah, A.; Ichesco, E.; Quintero, A.; Clauw, D.J.; Sundgren, P.C.

2012-01-01

Temporomandibular disorders (TMD) include craniocervical pain conditions with unclear etiologies. Central changes are suspected; however, few neuroimaging studies of TMD exist. Single-voxel proton magnetic resonance spectroscopy (1H-MRS) was used before and after pressure-pain testing to assess glutamate (Glu), glutamine (Gln), N-acetylaspartate (NAA), and choline (Cho) levels in the right and left posterior insulae of 11 individuals with myofascial TMD and 11 matched control individuals. Glu levels were significantly lower in all individuals after pain testing. Among those with TMD, left-insular Gln levels were related to reported pain, left posterior insular NAA and Cho levels were significantly higher at baseline than in control individuals, and NAA levels were significantly correlated with pain-symptom duration, suggesting adaptive changes. The results suggest that significant central cellular and molecular changes can occur in individuals with TMD. PMID:22451533

Isotopic Resonance Hypothesis: Experimental Verification by Escherichia coli Growth Measurements

NASA Astrophysics Data System (ADS)

Xie, Xueshu; Zubarev, Roman A.

2015-03-01

Isotopic composition of reactants affects the rates of chemical and biochemical reactions. As a rule, enrichment of heavy stable isotopes leads to progressively slower reactions. But the recent isotopic resonance hypothesis suggests that the dependence of the reaction rate upon the enrichment degree is not monotonous. Instead, at some ``resonance'' isotopic compositions, the kinetics increases, while at ``off-resonance'' compositions the same reactions progress slower. To test the predictions of this hypothesis for the elements C, H, N and O, we designed a precise (standard error +/-0.05%) experiment that measures the parameters of bacterial growth in minimal media with varying isotopic composition. A number of predicted resonance conditions were tested, with significant enhancements in kinetics discovered at these conditions. The combined statistics extremely strongly supports the validity of the isotopic resonance phenomenon (p << 10-15). This phenomenon has numerous implications for the origin of life studies and astrobiology, and possible applications in agriculture, biotechnology, medicine, chemistry and other areas.

Drag Reduction Devices for Aircraft (Latest Citations from the Aerospace Database)

NASA Technical Reports Server (NTRS)

1996-01-01

The bibliography contains citations concerning the modeling, application, testing, and development of drag reduction devices for aircraft. Slots, flaps, fences, large-eddy breakup (LEBU) devices, vortex generators and turbines, Helmholtz resonators, and winglets are among the devices discussed. Contour shaping to ensure laminar flow, control boundary layer transition, or minimize turbulence is also covered. Applications include the wings, nacelles, fuselage, empennage, and externals of aircraft designed for high-lift, subsonic, or supersonic operation. The design, testing, and development of directional grooves, commonly called riblets, are covered in a separate bibliography.(Contains 50-250 citations and includes a subject term index and title list.)

Structural Correlates of Reading the Mind in the Eyes in Autism Spectrum Disorder.

PubMed

Sato, Wataru; Uono, Shota; Kochiyama, Takanori; Yoshimura, Sayaka; Sawada, Reiko; Kubota, Yasutaka; Sakihama, Morimitsu; Toichi, Motomi

2017-01-01

Behavioral studies have shown that individuals with autism spectrum disorder (ASD) have impaired ability to read the mind in the eyes. Although this impairment is central to their social malfunctioning, its structural neural correlates remain unclear. To investigate this issue, we assessed Reading the Mind in the Eyes Test, revised version (Eyes Test) and acquired structural magnetic resonance images in adults with high-functioning ASD ( n = 19) and age-, sex- and intelligence quotient-matched typically developing (TD) controls ( n = 19). On the behavioral level, the Eyes Test scores were lower in the ASD group than in the control group. On the neural level, an interaction between group and Eyes Test score was found in the left temporoparietal junction (TPJ). A positive association between the Eyes Test score and gray matter volume of this region was evident in the control group, but not in the ASD group. This finding suggests that the failure to develop appropriate structural neural representations in the TPJ may underlie the impaired ability of individuals with ASD to read the mind in the eyes. These behavioral and neural findings provide support for the theories that impairments in processing eyes and the ability to infer others' mental states are the core symptoms of ASD, and that atypical features in the social brain network underlie such impairments.

Power processor for a 30cm ion thruster

NASA Technical Reports Server (NTRS)

Biess, J. J.; Inouye, L. Y.

1974-01-01

A thermal vacuum power processor for the NASA Lewis 30cm Mercury Ion Engine was designed, fabricated and tested to determine compliance with electrical specifications. The power processor breadboard used the silicon controlled rectifier (SCR) series resonant inverter as the basic power stage to process all the power to an ion engine. The power processor includes a digital interface unit to process all input commands and internal telemetry signals so that operation is compatible with a central computer system. The breadboard was tested in a thermal vacuum environment. Integration tests were performed with the ion engine and demonstrate operational compatibility and reliable operation without any component failures. Electromagnetic interference data were also recorded on the design to provide information on the interaction with total spacecraft.

Controlling Nanoantenna Polarizability through Backaction via a Single Cavity Mode

NASA Astrophysics Data System (ADS)

Ruesink, Freek; Doeleman, Hugo M.; Verhagen, Ewold; Koenderink, A. Femius

2018-05-01

The polarizability α determines the absorption, extinction, and scattering by small particles. Beyond being purely set by scatterer size and material, in fact polarizability can be affected by backaction: the influence of the photonic environment on the scatterer. As such, controlling the strength of backaction provides a tool to tailor the (radiative) properties of nanoparticles. Here, we control the backaction between broadband scatterers and a single mode of a high-quality cavity. We demonstrate that backaction from a microtoroid ring resonator significantly alters the polarizability of an array of nanorods: the polarizability is renormalized as fields scattered from—and returning to—the nanorods via the ring resonator depolarize the rods. Moreover, we show that it is possible to control the strength of the backaction by exploiting the diffractive properties of the array. This perturbation of a strong scatterer by a nearby cavity has important implications for hybrid plasmonic-photonic resonators and the understanding of coupled optical resonators in general.

What's the appeal? Testing public service advertisements to raise awareness about gynecologic cancer.

PubMed

Cooper, Crystale Purvis; Gelb, Cynthia A; Chu, Jennifer

2014-06-01

In 2013, the Centers for Disease Control and Prevention's (CDC) Inside Knowledge: Get the Facts About Gynecologic Cancer campaign tested creative concepts for English- and Spanish-language video advertisements (for use on television and the Internet) with women aged 35-64 years. Sixteen English and nine Spanish focus groups were conducted in four U.S. cities. CDC used animatics (a series of photographs edited together with a sound track) to simulate produced advertisements, without having to incur the high cost of filming and production. Advertisement concepts consistently resonating with participants featured cancer survivors, were straightforward, included information about cancer symptoms, displayed Inside Knowledge educational materials, and featured diverse women. In the general population focus groups, a primacy testing order effect was observed in which the concept tested first tended to be the most favorably received. Varying the order in which concepts were tested and considering testing order when interpreting results was critical.

Development and assessment of a fiber-optic liquid level sensor with long-period fiber grating and Shewhart control charts

NASA Astrophysics Data System (ADS)

Wang, Jian-Neng; Jan, Chen-Han; Tang, Jaw-Luen; Wu, Wei-Te; Chen, Der-Cheng; Chen, Chien-Hsing; Syu, Jial-Yan; Luo, Ching-Ying

2011-12-01

This paper presents the development and assessment of a liquid level sensor using long-period fiber grating (LPFG) technology and Shewhart control charts. The 22-mm LPFGs were fabricated with the point-by-point CO2 laser engraving method. This sensor was designed in such a way that it could be moved up and down with a position controller. The experimental section covered LPFG position sensing test, liquid level detection capacity and reliability measurements, and sensing resolution evaluation. LPFG position sensing test was studied and confirmed by the resonance wavelength shifts which were significantly generated when 75% of the LPFG was immersed in water. There were ten groups of different liquid level capacity testing and each group underwent ten repeated measurements. Based on Shewhart control charts including an X-bar chart, s chart, and R chart, the results showed all measurands within the upper and lower control limits. This sensor was reliable and the liquid level could be measured at least 1000 mm. The transmission loss versus the percent of immersion of the LPFG sensor for water and green tea was used to study the sensing resolution. The findings show the LPFG-based liquid sensor had at least 1000-mm level measurement capacity and about 2-mm resolution.

Description of a 2.3 kW power transformer for space applications

NASA Technical Reports Server (NTRS)

Hansen, I.

1979-01-01

The principle features and special testing of a high voltage high power transformer designed and developed for space application are described. The transformer is operated in a series resonant inverter supplying beam power to a 30 cm mercury ion thruster. Electrical requirements include operation of 2.3 kW continuous power output, primary currents to 35 amps rms, and frequencies up to 20 kHz. High efficiency was obtained through detailed considerations of the tradeoffs available in core materials, wire selection, coil configurations and thermal control. A number of novel heat removal techniques are discussed which control the winding temperature using only the available conductive cooling.

Dynamic characterization of high damping viscoelastic materials from vibration test data

NASA Astrophysics Data System (ADS)

Martinez-Agirre, Manex; Elejabarrieta, María Jesús

2011-08-01

The numerical analysis and design of structural systems involving viscoelastic damping materials require knowledge of material properties and proper mathematical models. A new inverse method for the dynamic characterization of high damping and strong frequency-dependent viscoelastic materials from vibration test data measured by forced vibration tests with resonance is presented. Classical material parameter extraction methods are reviewed; their accuracy for characterizing high damping materials is discussed; and the bases of the new analysis method are detailed. The proposed inverse method minimizes the residue between the experimental and theoretical dynamic response at certain discrete frequencies selected by the user in order to identify the parameters of the material constitutive model. Thus, the material properties are identified in the whole bandwidth under study and not just at resonances. Moreover, the use of control frequencies makes the method insensitive to experimental noise and the efficiency is notably enhanced. Therefore, the number of tests required is drastically reduced and the overall process is carried out faster and more accurately. The effectiveness of the proposed method is demonstrated with the characterization of a CLD (constrained layer damping) cantilever beam. First, the elastic properties of the constraining layers are identified from the dynamic response of a metallic cantilever beam. Then, the viscoelastic properties of the core, represented by a four-parameter fractional derivative model, are identified from the dynamic response of a CLD cantilever beam.

Active tuning of high-Q dielectric metasurfaces

DOE PAGES

Parry, Matthew; Komar, Andrei; Hopkins, Ben; ...

2017-08-02

Here, we demonstrate the active tuning of all-dielectric metasurfaces exhibiting high-quality factor (high-Q) resonances. The active control is provided by embedding the asymmetric silicon meta-atoms with liquid crystals, which allows the relative index of refraction to be controlled through heating. It is found that high quality factor resonances (Q = 270 ± 30) can be tuned over more than three resonance widths. Our results demonstrate the feasibility of using all-dielectric metasurfaces to construct tunable narrow-band filters.

A proposed method for electronic feedback compensation of damping in ferromagnetic resonance

DOE PAGES

Zohar, S.; Sterbinsky, G. E.

2017-07-10

Here, we propose an experimental technique for extending feedback compensation of dissipative radiation used in nuclear magnetic resonance (NMR) to encompass ferromagnetic resonance (FMR). This method uses a balanced microwave power detector whose output is phase shifted π/2, amplified, and fed back to drive precession. Using classical control theory, we predict an electronically controllable narrowing of field swept FMR line-widths. This technique is predicted to compensate other sources of spin dissipation in addition to radiative loss.

Time-delayed feedback control of coherence resonance chimeras

NASA Astrophysics Data System (ADS)

Zakharova, Anna; Semenova, Nadezhda; Anishchenko, Vadim; Schöll, Eckehard

2017-11-01

Using the model of a FitzHugh-Nagumo system in the excitable regime, we investigate the influence of time-delayed feedback on noise-induced chimera states in a network with nonlocal coupling, i.e., coherence resonance chimeras. It is shown that time-delayed feedback allows for the control of the range of parameter values where these chimera states occur. Moreover, for the feedback delay close to the intrinsic period of the system, we find a novel regime which we call period-two coherence resonance chimera.

Zero energy-storage ballast for compact fluorescent lamps

DOEpatents

Schultz, W.N.; Thomas, R.J.

1999-08-31

A CFL ballast includes complementary-type switching devices connected in series with their gates connected together at a control node. The switching devices supply a resonant tank circuit which is tuned to a frequency near, but slightly lower than, the resonant frequency of a resonant control circuit. As a result, the tank circuit restarts oscillations immediately following each zero crossing of the bus voltage. Such rapid restarts avoid undesirable flickering while maintaining the operational advantages and high efficacy of the CFL ballast. 4 figs.

Zero energy-storage ballast for compact fluorescent lamps

DOEpatents

Schultz, William Newell; Thomas, Robert James

1999-01-01

A CFL ballast includes complementary-type switching devices connected in series with their gates connected together at a control node. The switching devices supply a resonant tank circuit which is tuned to a frequency near, but slightly lower than, the resonant frequency of a resonant control circuit. As a result, the tank circuit restarts oscillations immediately following each zero crossing of the bus voltage. Such rapid restarts avoid undesirable flickering while maintaining the operational advantages and high efficacy of the CFL ballast.

A proposed method for electronic feedback compensation of damping in ferromagnetic resonance

NASA Astrophysics Data System (ADS)

Zohar, S.; Sterbinsky, G. E.

2017-12-01

We propose an experimental technique for extending feedback compensation of dissipative radiation used in nuclear magnetic resonance (NMR) to encompass ferromagnetic resonance (FMR). This method uses a balanced microwave power detector whose output is phase shifted π / 2 , amplified, and fed back to drive precession. Using classical control theory, we predict an electronically controllable narrowing of field swept FMR line-widths. This technique is predicted to compensate other sources of spin dissipation in addition to radiative loss.

Tunable cavity resonator including a plurality of MEMS beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peroulis, Dimitrios; Fruehling, Adam; Small, Joshua Azariah

A tunable cavity resonator includes a substrate, a cap structure, and a tuning assembly. The cap structure extends from the substrate, and at least one of the substrate and the cap structure defines a resonator cavity. The tuning assembly is positioned at least partially within the resonator cavity. The tuning assembly includes a plurality of fixed-fixed MEMS beams configured for controllable movement relative to the substrate between an activated position and a deactivated position in order to tune a resonant frequency of the tunable cavity resonator.

Measurement of optical Feshbach resonances in an ideal gas.

PubMed

Blatt, S; Nicholson, T L; Bloom, B J; Williams, J R; Thomsen, J W; Julienne, P S; Ye, J

2011-08-12

Using a narrow intercombination line in alkaline earth atoms to mitigate large inelastic losses, we explore the optical Feshbach resonance effect in an ultracold gas of bosonic (88)Sr. A systematic measurement of three resonances allows precise determinations of the optical Feshbach resonance strength and scaling law, in agreement with coupled-channel theory. Resonant enhancement of the complex scattering length leads to thermalization mediated by elastic and inelastic collisions in an otherwise ideal gas. Optical Feshbach resonance could be used to control atomic interactions with high spatial and temporal resolution.

Machine-Specific Magnetic Resonance Imaging Quality Control Procedures for Stereotactic Radiosurgery Treatment Planning

PubMed Central

Taghizadeh, Somayeh; Yang, Claus Chunli; R. Kanakamedala, Madhava; Morris, Bart; Vijayakumar, Srinivasan

2017-01-01

Purpose Magnetic resonance (MR) images are necessary for accurate contouring of intracranial targets, determination of gross target volume and evaluation of organs at risk during stereotactic radiosurgery (SRS) treatment planning procedures. Many centers use magnetic resonance imaging (MRI) simulators or regular diagnostic MRI machines for SRS treatment planning; while both types of machine require two stages of quality control (QC), both machine- and patient-specific, before use for SRS, no accepted guidelines for such QC currently exist. This article describes appropriate machine-specific QC procedures for SRS applications. Methods and materials We describe the adaptation of American College of Radiology (ACR)-recommended QC tests using an ACR MRI phantom for SRS treatment planning. In addition, commercial Quasar MRID3D and Quasar GRID3D phantoms were used to evaluate the effects of static magnetic field (B0) inhomogeneity, gradient nonlinearity, and a Leksell G frame (SRS frame) and its accessories on geometrical distortion in MR images. Results QC procedures found in-plane distortions (Maximum = 3.5 mm, Mean = 0.91 mm, Standard deviation = 0.67 mm, >2.5 mm (%) = 2) in X-direction (Maximum = 2.51 mm, Mean = 0.52 mm, Standard deviation = 0.39 mm, > 2.5 mm (%) = 0) and in Y-direction (Maximum = 13. 1 mm , Mean = 2.38 mm, Standard deviation = 2.45 mm, > 2.5 mm (%) = 34) in Z-direction and < 1 mm distortion at a head-sized region of interest. MR images acquired using a Leksell G frame and localization devices showed a mean absolute deviation of 2.3 mm from isocenter. The results of modified ACR tests were all within recommended limits, and baseline measurements have been defined for regular weekly QC tests. Conclusions With appropriate QC procedures in place, it is possible to routinely obtain clinically useful MR images suitable for SRS treatment planning purposes. MRI examination for SRS planning can benefit from the improved localization and planning possible with the superior image quality and soft tissue contrast achieved under optimal conditions. PMID:29487771

Machine-Specific Magnetic Resonance Imaging Quality Control Procedures for Stereotactic Radiosurgery Treatment Planning.

PubMed

Fatemi, Ali; Taghizadeh, Somayeh; Yang, Claus Chunli; R Kanakamedala, Madhava; Morris, Bart; Vijayakumar, Srinivasan

2017-12-18

Purpose Magnetic resonance (MR) images are necessary for accurate contouring of intracranial targets, determination of gross target volume and evaluation of organs at risk during stereotactic radiosurgery (SRS) treatment planning procedures. Many centers use magnetic resonance imaging (MRI) simulators or regular diagnostic MRI machines for SRS treatment planning; while both types of machine require two stages of quality control (QC), both machine- and patient-specific, before use for SRS, no accepted guidelines for such QC currently exist. This article describes appropriate machine-specific QC procedures for SRS applications. Methods and materials We describe the adaptation of American College of Radiology (ACR)-recommended QC tests using an ACR MRI phantom for SRS treatment planning. In addition, commercial Quasar MRID 3D and Quasar GRID 3D phantoms were used to evaluate the effects of static magnetic field (B 0 ) inhomogeneity, gradient nonlinearity, and a Leksell G frame (SRS frame) and its accessories on geometrical distortion in MR images. Results QC procedures found in-plane distortions (Maximum = 3.5 mm, Mean = 0.91 mm, Standard deviation = 0.67 mm, >2.5 mm (%) = 2) in X-direction (Maximum = 2.51 mm, Mean = 0.52 mm, Standard deviation = 0.39 mm, > 2.5 mm (%) = 0) and in Y-direction (Maximum = 13. 1 mm , Mean = 2.38 mm, Standard deviation = 2.45 mm, > 2.5 mm (%) = 34) in Z-direction and < 1 mm distortion at a head-sized region of interest. MR images acquired using a Leksell G frame and localization devices showed a mean absolute deviation of 2.3 mm from isocenter. The results of modified ACR tests were all within recommended limits, and baseline measurements have been defined for regular weekly QC tests. Conclusions With appropriate QC procedures in place, it is possible to routinely obtain clinically useful MR images suitable for SRS treatment planning purposes. MRI examination for SRS planning can benefit from the improved localization and planning possible with the superior image quality and soft tissue contrast achieved under optimal conditions.

Method for digital measurement of phase-frequency characteristics for a fixed-length ultrasonic spectrometer

NASA Astrophysics Data System (ADS)

Astashev, M. E.; Belosludtsev, K. N.; Kharakoz, D. P.

2014-05-01

One of the most accurate methods for measuring the compressibility of liquids is resonance measurement of sound velocity in a fixed-length interferometer. This method combines high sensitivity, accuracy, and small sample volume of the test liquid. The measuring principle is to study the resonance properties of a composite resonator that contains a test liquid sample. Ealier, the phase-locked loop (PLL) scheme was used for this. In this paper, we propose an alternative measurement scheme based on digital analysis of harmonic signals, describe the implementation of this scheme using commercially available data acquisition modules, and give examples of test measurements with accuracy evaluations of the results.

Theory of electrically controlled resonant tunneling spin devices

NASA Technical Reports Server (NTRS)

Ting, David Z. -Y.; Cartoixa, Xavier

2004-01-01

We report device concepts that exploit spin-orbit coupling for creating spin polarized current sources using nonmagnetic semiconductor resonant tunneling heterostructures, without external magnetic fields. The resonant interband tunneling psin filter exploits large valence band spin-orbit interaction to provide strong spin selectivity.

Method and apparatus for resonant frequency waveform modulation

DOEpatents

Taubman, Matthew S [Richland, WA

2011-06-07

A resonant modulator device and process are described that provide enhanced resonant frequency waveforms to electrical devices including, e.g., laser devices. Faster, larger, and more complex modulation waveforms are obtained than can be obtained by use of conventional current controllers alone.

Practical applications of nondestructive materials characterization

NASA Astrophysics Data System (ADS)

Green, Robert E., Jr.

1992-10-01

Nondestructive evaluation (NDE) techniques are reviewed for applications to the industrial production of materials including microstructural, physical, and chemical analyses. NDE techniques addressed include: (1) double-pulse holographic interferometry for sealed-package leak testing; (2) process controls for noncontact metals fabrication; (3) ultrasonic detections of oxygen contamination in titanium welds; and (4) scanning acoustic microscopy for the evaluation of solder bonds. The use of embedded sensors and emerging NDE concepts provides the means for controlling the manufacturing and quality of quartz crystal resonators, nickel single-crystal turbine blades, and integrated circuits. Advances in sensor technology and artificial intelligence algorithms and the use of embedded sensors combine to make NDE technology highly effective in controlling industrial materials manufacturing and the quality of the products.

Piezoelectric thin films and their applications for electronics

NASA Astrophysics Data System (ADS)

Yoshino, Yukio

2009-03-01

ZnO and AlN piezoelectric thin films have been studied for applications in bulk acoustic wave (BAW) resonator. This article introduces methods of forming ZnO and AlN piezoelectric thin films by radio frequency sputtering and applications of BAW resonators considering the relationship between the crystallinity of piezoelectric thin films and the characteristics of the BAW resonators. Using ZnO thin films, BAW resonators were fabricated for a contour mode at 3.58 MHz and thickness modes from 200 MHz to 5 GHz. The ZnO thin films were combined with various materials, substrates, and thin films to minimize the temperature coefficient of frequency (TCF). The minimum TCF of BAW resonators was approximately 2 ppm/°C in the range -20 to 80 °C. The electromechanical coupling coefficient (k2) in a 1.9 GHz BAW resonator was 6.9%. Using AlN thin films, 5-20 GHz BAW resonators with an ultrathin membrane were realized. The membrane thickness of a 20 GHz BAW resonator was about 200 nm, k2 was 6.1%, and the quality factor (Q) was about 280. Q decreased with increasing resonant frequency. The value of k2 is almost the same for 5-20 GHz resonators. This result could be obtained by improving the thickness uniformity, by controlling internal stress of thin films, and by controlling the crystallinity of AlN piezoelectric thin film.

Tunable resonant and non-resonant interactions between a phase qubit and LC resonator

NASA Astrophysics Data System (ADS)

Allman, Michael Shane; Whittaker, Jed D.; Castellanos-Beltran, Manuel; Cicak, Katarina; da Silva, Fabio; Defeo, Michael; Lecocq, Florent; Sirois, Adam; Teufel, John; Aumentado, Jose; Simmonds, Raymond W.

2014-03-01

We use a flux-biased radio frequency superconducting quantum interference device (rf SQUID) with an embedded flux-biased direct current (dc) SQUID to generate strong resonant and non-resonant tunable interactions between a phase qubit and a lumped-element resonator. The rf-SQUID creates a tunable magnetic susceptibility between the qubit and resonator providing resonant coupling rates from zero to near the ultra-strong coupling regime. By modulating the magnetic susceptibility, non-resonant parametric coupling achieves rates > 100 MHz . Nonlinearity of the magnetic susceptibility also leads to parametric coupling at subharmonics of the qubit-resonator detuning. Controllable coupling is generically important for constructing coupled-mode systems ubiquitous in physics, useful for both, quantum information architectures and quantum simulators. This work supported by NIST and NSA grant EAO140639.

Storage and on-demand release of microwaves using superconducting resonators with tunable coupling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pierre, Mathieu, E-mail: mathieu.pierre@lncmi.cnrs.fr; Svensson, Ida-Maria; Raman Sathyamoorthy, Sankar

2014-06-09

We present a system which allows to tune the coupling between a superconducting resonator and a transmission line. This storage resonator is addressed through a second, coupling resonator, which is frequency-tunable and controlled by a magnetic flux applied to a superconducting quantum interference device. We experimentally demonstrate that the lifetime of the storage resonator can be tuned by more than three orders of magnitude. A field can be stored for 18 μs when the coupling resonator is tuned off resonance and it can be released in 14 ns when the coupling resonator is tuned on resonance. The device allows capture, storage, andmore » on-demand release of microwaves at a tunable rate.« less

Juicy lemons for measuring basic empathic resonance.

PubMed

Hagenmuller, Florence; Rössler, Wulf; Wittwer, Amrei; Haker, Helene

2014-10-30

Watch or even think of someone biting into a juicy lemon and your saliva will flow. This is a phenomenon of resonance, best described by the Perception-Action Model, where a physiological state in a person is activated through observation of this state in another. Within a broad framework of empathy, including manifold abilities depending on the Perception-Action link, resonance has been proposed as one physiological substrate for empathy. Using 49 healthy subjects, we developed a standardized salivation paradigm to assess empathic resonance at the autonomic level. Our results showed that this physiological resonance correlated positively with self-reported empathic concern. The salivation test, delivered an objective and continuous measure, was simple to implement in terms of setup and instruction, and could not easily be unintentionally biased or intentionally manipulated by participants. Therefore, these advantages make such a test a useful tool for assessing empathy-related abilities in psychiatric populations. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Electromagnon Resonance at Room Temperature with Gigantic Magnetochromism

NASA Astrophysics Data System (ADS)

Shishikura, H.; Tokunaga, Y.; Takahashi, Y.; Masuda, R.; Taguchi, Y.; Kaneko, Y.; Tokura, Y.

2018-04-01

The elementary excitation characteristic of magnetoelectric (ME) multiferroics is a magnon endowed with electric activity, which is referred to as an electromagnon. The electromagnon resonance mediated by the bilinear exchange coupling potentially exhibits strong terahertz light-matter interaction with optical properties different from the conventional magnon excitation. Here we report the robust electromagnon resonance on helimagnetic Y -type hexaferrites in a wide temperature range including room temperature. Furthermore, the efficient magnetic field controls of the electromagnon are demonstrated on the flexible spin structure of these compounds, leading to the generation or annihilation of the resonance as well as the large resonance energy shift. These terahertz characteristics of the electromagnon exemplify the versatile magneto-optical functionality driven by the ME coupling in multiferroics, paving a way for possible terahertz applications as well as terahertz control of a magnetic state of matter.

It's like being in another world--patients' lived experience of magnetic resonance imaging.

PubMed

Törnqvist, Erna; Månsson, Asa; Larsson, Elna-Marie; Hallström, Inger

2006-08-01

The aim of this study was to illuminate patients' lived experience during magnetic resonance imaging. Magnetic resonance imaging has increased in importance since the early 1980s and is today a common useful diagnostic tool. Although magnetic resonance imaging are non-invasive and considered painless, many patients experience anxiety, sometimes so strong that the scan has to be terminated. The study had an inductive design and a hermeneutic phenomenological methodology was used. The essential theme of going through magnetic resonance imaging was a feeling of being in another world. The strange environment and isolation inside the scanner made the participants' experiences unusual, with varying degrees of difficulty dealing with it. Being in the other world caused a threat to the participants' self-control. There was a relation between threat to self-control, effort and need for support in the sense that the magnitude of threat to self-control had an impact on the effort it took to handle the situation and on the need for support, and conversely that the support received could affect the effort and threat to self-control. The study shows that the information received and the interaction between patients and staff have a significant influence on patients' lived experiences. The individual experience of threat to self-control requires the need for support to be individualized and care need to be adjusted for each patient.

Fan noise control using Herschel-Quincke resonators on a production turbofan engine

NASA Astrophysics Data System (ADS)

Burdisso, Ricardo A.; Gerhold, Carl H.

2002-05-01

The Herschel-Quincke (HQ) resonator concept is an innovative technique that consists of installing circumferential arrays of HQ waveguides around the inlet of a turbofan engine. An HQ waveguide is essentially a hollow side tube that travels along (but not necessarily parallel to) the engine axis and attaches to the inlet at each of the two ends of the tube. To investigate the potential of the concept, the approach was tested on a full-scale production Honeywell TFE731-60 engine. An HQ-inlet system containing two arrays was designed to attenuate the blade passage frequency (BPF) tone at approach condition, i.e., 60% engine power. However, the system was tested over the full range of engine power settings. The effects of each array both individually and together were evaluated as compared to the hard-wall case. Both far-field and induct data were recorded during the tests. The results show good attenuation of both the BPF tone and broadband components. Furthermore, reduction of ``buzz-saw'' tones, i.e., additional tones radiated from the inlet when the fan-tip speed goes supersonic, was observed with the HQ system. Some fan distortion effects and increase in noise was observed at higher engine speeds. [Work supported by NASA Langley Research Center.

High-resolution surface plasmon resonance biosensing system for glucose concentration detecting

NASA Astrophysics Data System (ADS)

Huang, Xian; Li, Dachao; Yu, Haixia; Huang, Fuxiang; Hu, Xiaotang; Xu, Kexin

2007-02-01

Glucose is one of the most important substances widely contained in organism and food, thus people pay much attention in researching and improving the way for the detection of glucose. Traditional ways, although precise and reliable when in high concentration and large amount of sample, have unconvincing performance in detecting mixture and solution with low concentration and micro-volume. As far as the ideal way is concerned, it should not only specifically detect the glucose and exclude other components in solution, but also meet the need of micro-sample (approximately 5μL) and low concentration. We introduced D-galactose/D-glucose Binding Protein (GGBP) - a kind of protein which has the ability to absorb the glucose specifically, to construct a novel surface plasmon resonance measuring system. By immobilizing GGBP onto the surface of the SPR sensor, we develop a new detecting system for glucose testing in mixed solution. The experimental result indicates that compared with 0.1g/L before immobilization of GGBP, the detecting limit or the resolution of glucose testing rises to 1mg/L after the immobilization, the system succeeds in distinguishing glucose from other components in mixture, which reveals a bright future to apply SPR in the minimally invasive diabetes testing and food quality control.

Measuring the Characteristic Topography of Brain Stiffness with Magnetic Resonance Elastography

PubMed Central

Murphy, Matthew C.; Huston, John; Jack, Clifford R.; Glaser, Kevin J.; Senjem, Matthew L.; Chen, Jun; Manduca, Armando; Felmlee, Joel P.; Ehman, Richard L.

2013-01-01

Purpose To develop a reliable magnetic resonance elastography (MRE)-based method for measuring regional brain stiffness. Methods First, simulation studies were used to demonstrate how stiffness measurements can be biased by changes in brain morphometry, such as those due to atrophy. Adaptive postprocessing methods were created that significantly reduce the spatial extent of edge artifacts and eliminate atrophy-related bias. Second, a pipeline for regional brain stiffness measurement was developed and evaluated for test-retest reliability in 10 healthy control subjects. Results This technique indicates high test-retest repeatability with a typical coefficient of variation of less than 1% for global brain stiffness and less than 2% for the lobes of the brain and the cerebellum. Furthermore, this study reveals that the brain possesses a characteristic topography of mechanical properties, and also that lobar stiffness measurements tend to correlate with one another within an individual. Conclusion The methods presented in this work are resistant to noise- and edge-related biases that are common in the field of brain MRE, demonstrate high test-retest reliability, and provide independent regional stiffness measurements. This pipeline will allow future investigations to measure changes to the brain’s mechanical properties and how they relate to the characteristic topographies that are typical of many neurologic diseases. PMID:24312570

Delayed Hippocampal Effects From a Single Exposure of Prepubertal Guinea Pigs to sub-lethal dose of Chlorpyrifos: A Magnetic Resonance Imaging and Spectroscopy Study

PubMed Central

Mullins, Roger J.; Xu, Su; Pereira, Edna F.R.; Mamczarz, Jacek; Albuquerque, Edson X.; Gullapalli, Rao P.

2013-01-01

This study was designed to test the hypothesis that in vivo Magnetic Resonance Imaging (MRI) and Spectroscopy (MRS) can detect in adulthood the neurotoxic effects of a single exposure of prepubertal guinea pigs to the organophosphorus pesticide chlorpyrifos. Twelve female guinea pigs were given either a single dose of chlorpyrifos (0.6xLD50 or 300 mg/kg, sc) or peanut oil (vehicle; 0.5 ml/kg, sc) at 35–40 days of age. One year after the exposure, the animals were tested in the Morris water maze. Three days after the end of the behavioral testing, the metabolic and structural integrity of the brain of the animals was examined by means of MRI/MRS. In the Morris water maze, the chlorpyrifos-exposed guinea pigs showed significant memory deficit. Although no significant anatomical differences were found between the chlorpyrifos-exposed guinea pigs and the control animals by in vivo MRI, the chlorpyrifos-exposed animals showed significant decreases in hippocampal myo-inositol concentration using MRS. The present results indicate that a single sub-lethal exposure of prepubertal guinea pigs to the organophosphorus pesticide chlorpyrifos can lead to long-term memory deficits that are accompanied by significant reductions in the levels of hippocampal myo-inositol. PMID:23411083

Diagnosis of toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome by using a new serologic method.

PubMed Central

Suzuki, Y; Israelski, D M; Dannemann, B R; Stepick-Biek, P; Thulliez, P; Remington, J S

1988-01-01

The present study was performed to develop a serological method for diagnosing toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome (AIDS). The trophozoite form of Toxoplasma gondii, fixed with either Formalin or acetone, was used in a modification of an agglutination method previously shown to differentiate between the acute and the chronic (latent) stages of infection with toxoplasma in immunologically normal persons. By using these antigens in separate tests and evaluating the data for statistical significance, 70% of patients with AIDS with biopsy-proven toxoplasmic encephalitis were distinguished from control, ambulatory patients with AIDS with toxoplasma antibodies but without signs or symptoms of central nervous system involvement. In a separate study, the agglutination tests identified from controls 84% of patients with AIDS with two or more brain lesions detected by computed-tomographic or magnetic-resonance-imaging scans and suspected of having toxoplasmic encephalitis. Thus, these agglutination tests should prove valuable for the noninvasive diagnosis of toxoplasmic encephalitis in patients with AIDS. PMID:3230132

The effects of receiving room dimensions and absorption in the measurement of impact insulation class (IIC) rating

NASA Astrophysics Data System (ADS)

Su, Rose Mary; Tocci, Gregory

2005-09-01

The measurement of the Impact Insulation Class (IIC) rating of any floor/ceiling construction requires the use of a certified laboratory space. In a recent investigation into the IIC rating of a new floor system, several tests were conducted in a certified laboratory. In many tests, the IIC rating was controlled by the 100-Hz 1/3-octave frequency band, despite changes in the floor/ceiling construction. The base floor/ceiling construction included a wood structural floor on open-web wood joists and a GWB ceiling below. This paper will investigate the possibility that room resonances influenced the IIC ratings of the several floor systems tested. These data will be compared with IIC data collected for the same floor construction with the GWB ceiling removed. The removal of the GWB ceiling increased the receiver room volume and exposed the glass fiber insulation to the receiver room, thus eliminating the control of the 100-Hz 1/3-octave band over the IIC rating.

Development of compact rapid charging power supply for capacitive energy storage in pulsed power drivers.

PubMed

Sharma, Surender Kumar; Shyam, Anurag

2015-02-01

High energy capacitor bank is used for primary electrical energy storage in pulsed power drivers. The capacitors used in these pulsed power drivers have low inductance, low internal resistance, and less dc life, so it has to be charged rapidly and immediately discharged into the load. A series resonant converter based 45 kV compact power supply is designed and developed for rapid charging of the capacitor bank with constant charging current up to 150 mA. It is short circuit proof, and zero current switching technique is used to commute the semiconductor switch. A high frequency resonant inverter switching at 10 kHz makes the overall size small and reduces the switching losses. The output current of the power supply is limited by constant on-time and variable frequency switching control technique. The power supply is tested by charging the 45 kV/1.67 μF and 15 kV/356 μF capacitor banks. It has charged the capacitor bank up to rated voltage with maximum charging current of 150 mA and the average charging rate of 3.4 kJ/s. The output current of the power supply is limited by reducing the switching frequency at 5 kHz, 3.3 kHz, and 1.7 kHz and tested with 45 kV/1.67 μF capacitor bank. The protection circuit is included in the power supply for over current, under voltage, and over temperature. The design details and the experimental testing results of the power supply for resonant current, output current, and voltage traces of the power supply with capacitive, resistive, and short circuited load are presented and discussed.

Testing the Foundations of Relativity Using Cryogenic Optical Resonators

NASA Astrophysics Data System (ADS)

Müller, H.; Braxmaier, C.; Herrmann, S.; Pradl, O.; Lämmerzahl, C.; Mlynek, J.; Schiller, S.; Peters, A.

We present a new generation of experiments using cryogenic optical resonators(COREs) to test the foundations of relativity. The experiments test the isotropy of the speed of light (Michelson-Morley experiment), the independece of the speed of light from the velocity of the laboratory (Kennedy-Thorndike experiments), and the gravitational redshift for clocks based on an electronic transition. Compared with the best previous results, our tests have already yielded improvements up to a factor of three. Future versions promise significant improvements.

Atomic resolution ultrafast scanning tunneling microscope with scan rate breaking the resonant frequency of a quartz tuning fork resonator.

PubMed

Li, Quanfeng; Lu, Qingyou

2011-05-01

We present an ultra-fast scanning tunneling microscope with atomic resolution at 26 kHz scan rate which surpasses the resonant frequency of the quartz tuning fork resonator used as the fast scan actuator. The main improvements employed in achieving this new record are (1) fully low voltage design (2) independent scan control and data acquisition, where the tuning fork (carrying a tip) is blindly driven to scan by a function generator with the scan voltage and tunneling current (I(T)) being measured as image data (this is unlike the traditional point-by-point move and measure method where data acquisition and scan control are switched many times).

Controllable surface-plasmon resonance in engineered nanometer epitaxial silicide particles embedded in silicon

NASA Technical Reports Server (NTRS)

Fathauer, R. W.; Ksendzov, A.; Iannelli, J. M.; George, T.

1991-01-01

Epitaxial CoSi2 particles in a single-crystal silicon matrix are grown by molecular-beam epitaxy using a technique that allows nanometer control over particle size in three dimensions. These composite layers exhibit resonant absorption predicted by effective-medium theory. Selection of the height and diameter of disklike particles through a choice of growth conditions allows tailoring of the depolarization factor and hence of the surface-plasmon resonance energy. Resonant absorption from 0.49 to 1.04 eV (2.5 to 1.2 micron) is demonstrated and shown to agree well with values predicted by the Garnett (1904, 1906) theory using the bulk dielectric constants for CoSi2 and Si.

Migraine classification using magnetic resonance imaging resting-state functional connectivity data.

PubMed

Chong, Catherine D; Gaw, Nathan; Fu, Yinlin; Li, Jing; Wu, Teresa; Schwedt, Todd J

2017-08-01

Background This study used machine-learning techniques to develop discriminative brain-connectivity biomarkers from resting-state functional magnetic resonance neuroimaging ( rs-fMRI) data that distinguish between individual migraine patients and healthy controls. Methods This study included 58 migraine patients (mean age = 36.3 years; SD = 11.5) and 50 healthy controls (mean age = 35.9 years; SD = 11.0). The functional connections of 33 seeded pain-related regions were used as input for a brain classification algorithm that tested the accuracy of determining whether an individual brain MRI belongs to someone with migraine or to a healthy control. Results The best classification accuracy using a 10-fold cross-validation method was 86.1%. Resting functional connectivity of the right middle temporal, posterior insula, middle cingulate, left ventromedial prefrontal and bilateral amygdala regions best discriminated the migraine brain from that of a healthy control. Migraineurs with longer disease durations were classified more accurately (>14 years; 96.7% accuracy) compared to migraineurs with shorter disease durations (≤14 years; 82.1% accuracy). Conclusions Classification of migraine using rs-fMRI provides insights into pain circuits that are altered in migraine and could potentially contribute to the development of a new, noninvasive migraine biomarker. Migraineurs with longer disease burden were classified more accurately than migraineurs with shorter disease burden, potentially indicating that disease duration leads to reorganization of brain circuitry.

3C-SiC microdisk mechanical resonators with multimode resonances at radio frequencies

NASA Astrophysics Data System (ADS)

Lee, Jaesung; Zamani, Hamidrera; Rajgopal, Srihari; Zorman, Christian A.; X-L Feng, Philip

2017-07-01

We report on the design, modeling, fabrication and measurement of single-crystal 3C-silicon carbide (SiC) microdisk mechanical resonators with multimode resonances operating at radio frequencies (RF). These microdisk resonators (center-clamped on a vertical stem pedestal) offer multiple flexural-mode resonances with frequencies dependent on both disk and anchor dimensions. The resonators are made using a novel fabrication method comprised of focused ion beam nanomachining and hydroflouic : nitric : acetic (HNA) acid etching. Resonance peaks (in the frequency spectrum) are detected through laser-interferometry measurements. Resonators with different dimensions are tested, and multimode resonances, mode splitting, energy dissipation (in the form of quality factor measurement) are investigated. Further, we demonstrate a feedback oscillator based on a passive 3C-SiC resonator. This investigation provides important guidelines for microdisk resonator development, ranging from an analytical prediction of frequency scaling law to fabrication, suggesting RF microdisk resonators can be good candidates for future sensing applications in harsh environments.

Codimension-Two Bifurcation, Chaos and Control in a Discrete-Time Information Diffusion Model

NASA Astrophysics Data System (ADS)

Ren, Jingli; Yu, Liping

2016-12-01

In this paper, we present a discrete model to illustrate how two pieces of information interact with online social networks and investigate the dynamics of discrete-time information diffusion model in three types: reverse type, intervention type and mutualistic type. It is found that the model has orbits with period 2, 4, 6, 8, 12, 16, 20, 30, quasiperiodic orbit, and undergoes heteroclinic bifurcation near 1:2 point, a homoclinic structure near 1:3 resonance point and an invariant cycle bifurcated by period 4 orbit near 1:4 resonance point. Moreover, in order to regulate information diffusion process and information security, we give two control strategies, the hybrid control method and the feedback controller of polynomial functions, to control chaos, flip bifurcation, 1:2, 1:3 and 1:4 resonances, respectively, in the two-dimensional discrete system.

Design and Verification of a Digital Controller for a 2-Piece Hemispherical Resonator Gyroscope

PubMed Central

Lee, Jungshin; Yun, Sung Wook; Rhim, Jaewook

2016-01-01

A Hemispherical Resonator Gyro (HRG) is the Coriolis Vibratory Gyro (CVG) that measures rotation angle or angular velocity using Coriolis force acting the vibrating mass. A HRG can be used as a rate gyro or integrating gyro without structural modification by simply changing the control scheme. In this paper, differential control algorithms are designed for a 2-piece HRG. To design a precision controller, the electromechanical modelling and signal processing must be pre-performed accurately. Therefore, the equations of motion for the HRG resonator with switched harmonic excitations are derived with the Duhamel Integral method. Electromechanical modeling of the resonator, electric module and charge amplifier is performed by considering the mode shape of a thin hemispherical shell. Further, signal processing and control algorithms are designed. The multi-flexing scheme of sensing, driving cycles and x, y-axis switching cycles is appropriate for high precision and low maneuverability systems. The differential control scheme is easily capable of rejecting the common mode errors of x, y-axis signals and changing the rate integrating mode on basis of these studies. In the rate gyro mode the controller is composed of Phase-Locked Loop (PLL), amplitude, quadrature and rate control loop. All controllers are designed on basis of a digital PI controller. The signal processing and control algorithms are verified through Matlab/Simulink simulations. Finally, a FPGA and DSP board with these algorithms is verified through experiments. PMID:27104539

Secular resonances between bodies on close orbits II: prograde and retrograde orbits for irregular satellites

NASA Astrophysics Data System (ADS)

Li, Daohai; Christou, Apostolos A.

2017-09-01

In extending the analysis of the four secular resonances between close orbits in Li and Christou (Celest Mech Dyn Astron 125:133-160, 2016) (Paper I), we generalise the semianalytical model so that it applies to both prograde and retrograde orbits with a one-to-one map between the resonances in the two regimes. We propose the general form of the critical angle to be a linear combination of apsidal and nodal differences between the two orbits b_1 Δ π + b_2 Δ Ω, forming a collection of secular resonances in which the ones studied in Paper I are among the strongest. Test of the model in the orbital vicinity of massive satellites with physical and orbital parameters similar to those of the irregular satellites Himalia at Jupiter and Phoebe at Saturn shows that {>}20 and {>}40% of phase space is affected by these resonances, respectively. The survivability of the resonances is confirmed using numerical integration of the full Newtonian equations of motion. We observe that the lowest order resonances with b_1+|b_2|≤ 3 persist, while even higher-order resonances, up to b_1+|b_2|≥ 7, survive. Depending on the mass, between 10 and 60% of the integrated test particles are captured in these secular resonances, in agreement with the phase space analysis in the semianalytical model.

Controlled dipole-dipole interactions between K Rydberg atoms in a laser-chopped effusive beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kutteruf, M. R.; Jones, R. R.

2010-12-15

We explore pulsed-field control of resonant dipole-dipole interactions between K Rydberg atoms. A laser-based atomic beam chopper is used to reduce the relative velocities of Rydberg atoms excited from an effusive thermal source. Resonant energy transfer (RET) between pairs of atoms is controlled via Stark tuning of the relevant Rydberg energy levels. Resonance line shapes in the electric field dependence of the RET probability are used to determine the effective temperature of the sample. We demonstrate that the relative atom velocities can be reduced to the point where the duration of the electric-field tuning pulses, and not the motion ofmore » neighboring atoms, defines the interaction time for each pair within the ensemble. Coherent, transform-limited broadening of the resonance line shape is observed as the tuning pulse duration is reduced below the natural time scale for collisions.« less

Design and Analyses of a MEMS Based Resonant Magnetometer

PubMed Central

Ren, Dahai; Wu, Lingqi; Yan, Meizhi; Cui, Mingyang; You, Zheng; Hu, Muzhi

2009-01-01

A novel design of a MEMS torsional resonant magnetometer based on Lorentz force is presented and fabricated. The magnetometer consists of a silicon resonator, torsional beam, excitation coil, capacitance plates and glass substrate. Working in a resonant condition, the sensor’s vibration amplitude is converted into the sensing capacitance change, which reflects the outside magnetic flux-density. Based on the simulation, the key structure parameters are optimized and the air damping effect is estimated. The test results of the prototype are in accordance with the simulation results of the designed model. The resolution of the magnetometer can reach 30 nT. The test results indicate its sensitivity of more than 400 mV/μT when operating in a 10 Pa vacuum environment. PMID:22399981

The effects of physical activity on functional MRI activation associated with cognitive control in children: a randomized controlled intervention

PubMed Central

Chaddock-Heyman, Laura; Erickson, Kirk I.; Voss, Michelle W.; Knecht, Anya M.; Pontifex, Matthew B.; Castelli, Darla M.; Hillman, Charles H.; Kramer, Arthur F.

2013-01-01

This study used functional magnetic resonance imaging (fMRI) to examine the influence of a 9-month physical activity program on task-evoked brain activation during childhood. The results demonstrated that 8- to 9-year-old children who participated in 60+ min of physical activity, 5 days per week, for 9 months, showed decreases in fMRI brain activation in the right anterior prefrontal cortex coupled with within-group improvements in performance on a task of attentional and interference control. Children assigned to a wait-list control group did not show changes in brain function. Furthermore, at post-test, children in the physical activity group showed similar anterior frontal brain patterns and incongruent accuracy rates to a group of college-aged young adults. Children in the wait-list control group still differed from the young adults in terms of anterior prefrontal activation and performance at post-test. There were no significant changes in fMRI activation in the anterior cingulate cortex (ACC) for either group. These results suggest that physical activity during childhood may enhance specific elements of prefrontal cortex function involved in cognitive control. PMID:23487583

Engineering non-linear resonator mode interactions in circuit QED by continuous driving: Manipulation of a photonic quantum memory

NASA Astrophysics Data System (ADS)

Reagor, Matthew; Pfaff, Wolfgang; Heeres, Reinier; Ofek, Nissim; Chou, Kevin; Blumoff, Jacob; Leghtas, Zaki; Touzard, Steven; Sliwa, Katrina; Holland, Eric; Albert, Victor V.; Frunzio, Luigi; Devoret, Michel H.; Jiang, Liang; Schoelkopf, Robert J.

2015-03-01

Recent advances in circuit QED have shown great potential for using microwave resonators as quantum memories. In particular, it is possible to encode the state of a quantum bit in non-classical photonic states inside a high-Q linear resonator. An outstanding challenge is to perform controlled operations on such a photonic state. We demonstrate experimentally how a continuous drive on a transmon qubit coupled to a high-Q storage resonator can be used to induce non-linear dynamics of the resonator. Tailoring the drive properties allows us to cancel or enhance non-linearities in the system such that we can manipulate the state stored in the cavity. This approach can be used to either counteract undesirable evolution due to the bare Hamiltonian of the system or, ultimately, to perform logical operations on the state encoded in the cavity field. Our method provides a promising pathway towards performing universal control for quantum states stored in high-coherence resonators in the circuit QED platform.

Application of Probabilistic Methods to Assess Risk Due to Resonance in the Design of J-2X Rocket Engine Turbine Blades

NASA Technical Reports Server (NTRS)

Brown, Andrew M.; DeHaye, Michael; DeLessio, Steven

2011-01-01

The LOX-Hydrogen J-2X Rocket Engine, which is proposed for use as an upper-stage engine for numerous earth-to-orbit and heavy lift launch vehicle architectures, is presently in the design phase and will move shortly to the initial development test phase. Analysis of the design has revealed numerous potential resonance issues with hardware in the turbomachinery turbine-side flow-path. The analysis of the fuel pump turbine blades requires particular care because resonant failure of the blades, which are rotating in excess of 30,000 revolutions/minutes (RPM), could be catastrophic for the engine and the entire launch vehicle. This paper describes a series of probabilistic analyses performed to assess the risk of failure of the turbine blades due to resonant vibration during past and present test series. Some significant results are that the probability of failure during a single complete engine hot-fire test is low (1%) because of the small likelihood of resonance, but that the probability increases to around 30% for a more focused turbomachinery-only test because all speeds will be ramped through and there is a greater likelihood of dwelling at more speeds. These risk calculations have been invaluable for use by program management in deciding if risk-reduction methods such as dampers are necessary immediately or if the test can be performed before the risk-reduction hardware is ready.

Diminished neural and cognitive responses to facial expressions of disgust in patients with psoriasis: a functional magnetic resonance imaging study.

PubMed

Kleyn, C Elise; McKie, Shane; Ross, Andrew R; Montaldi, Daniela; Gregory, Lloyd J; Elliott, Rebecca; Isaacs, Clare L; Anderson, Ian M; Richards, Helen L; Deakin, J F William; Fortune, Donal G; Griffiths, Christopher E M

2009-11-01

Psoriasis produces significant psychosocial disability; however, little is understood about the neurocognitive mechanisms that mediate the adverse consequences of the social stigma associated with visible skin lesions, such as disgusted facial expressions of others. Both the feeling of disgust and the observation of disgust in others are known to activate the insula cortex. We investigated whether the social impact of psoriasis is associated with altered cognitive processing of disgust using (i) a covert recognition of faces task conducted using functional magnetic resonance imaging (fMRI) and (ii) the facial expression recognition task (FERT), a decision-making task, conducted outside the scanner to assess the ability to recognize overtly different intensities of disgust. Thirteen right-handed male patients with psoriasis and 13 age-matched male controls were included. In the fMRI study, psoriasis patients had significantly (P<0.005) smaller signal responses to disgusted faces in the bilateral insular cortex compared with healthy controls. These data were corroborated by FERT, in that patients were less able than controls to identify all intensities of disgust tested. We hypothesize that patients with psoriasis, in this case male patients, develop a coping mechanism to protect them from stressful emotional responses by blocking the processing of disgusted facial expressions.

Childhood temporal lobe epilepsy: correlation between electroencephalography and magnetic resonance spectroscopy: a case-control study.

PubMed

Azab, Seham Fa; Sherief, Laila M; Saleh, Safaa H; Elshafeiy, Mona M; Siam, Ahmed G; Elsaeed, Wafaa F; Arafa, Mohamed A; Bendary, Eman A; Sherbiny, Hanan S; Elbehedy, Rabab M; Aziz, Khalid A

2015-04-18

The diagnosis of epilepsy should be made as early as possible to give a child the best chance for treatment success and also to decrease complications such as learning difficulties and social and behavioral problems. In this study, we aimed to assess the ability of magnetic resonance spectroscopy (MRS) in detecting the lateralization side in patients with Temporal lobe epilepsy (TLE) in correlation with EEG and MRI findings. This was a case-control study including 40 patients diagnosed (clinically and by EEG) as having temporal lobe epilepsy aged 8 to 14 years (mean, 10.4 years) and 20 healthy children with comparable age and gender as the control group. All patients were subjected to clinical examination, interictal electroencephalography and magnetic resonance imaging (MRI). Proton magnetic resonance spectroscopic examination (MRS) was performed to the patients and the controls. According to the findings of electroencephalography, our patients were classified to three groups: Group 1 included 20 patients with unitemporal (lateralized) epileptic focus, group 2 included 12 patients with bitemporal (non-lateralized) epileptic focus and group 3 included 8 patients with normal electroencephalography. Magnetic resonance spectroscopy could lateralize the epileptic focus in 19 patients in group 1, nine patients in group2 and five patients in group 3 with overall lateralization of (82.5%), while electroencephalography was able to lateralize the focus in (50%) of patients and magnetic resonance imaging detected lateralization of mesial temporal sclerosis in (57.5%) of patients. Magnetic resonance spectroscopy is a promising tool in evaluating patients with epilepsy and offers increased sensitivity to detect temporal pathology that is not obvious on structural MRI imaging.

Alcohol consumption during adolescence is associated with reduced grey matter volumes.

PubMed

Heikkinen, Noora; Niskanen, Eini; Könönen, Mervi; Tolmunen, Tommi; Kekkonen, Virve; Kivimäki, Petri; Tanila, Heikki; Laukkanen, Eila; Vanninen, Ritva

2017-04-01

Cognitive impairment has been associated with excessive alcohol use, but its neural basis is poorly understood. Chronic excessive alcohol use in adolescence may lead to neuronal loss and volumetric changes in the brain. Our objective was to compare the grey matter volumes of heavy- and light-drinking adolescents. This was a longitudinal study: heavy-drinking adolescents without an alcohol use disorder and their light-drinking controls were followed-up for 10 years using questionnaires at three time-points. Magnetic resonance imaging was conducted at the last time-point. The area near Kuopio University Hospital, Finland. The 62 participants were aged 22-28 years and included 35 alcohol users and 27 controls who had been followed-up for approximately 10 years. Alcohol use was measured by the Alcohol Use Disorders Identification Test (AUDIT)-C at three time-points during 10 years. Participants were selected based on their AUDIT-C score. Magnetic resonance imaging was conducted at the last time-point. Grey matter volume was determined and compared between heavy- and light-drinking groups using voxel-based morphometry on three-dimensional T1-weighted magnetic resonance images using predefined regions of interest and a threshold of P < 0.05, with small volume correction applied on cluster level. Grey matter volumes were significantly smaller among heavy-drinking participants in the bilateral anterior cingulate cortex, right orbitofrontal and frontopolar cortex, right superior temporal gyrus and right insular cortex compared to the control group (P < 0.05, family-wise error-corrected cluster level). Excessive alcohol use during adolescence appears to be associated with an abnormal development of the brain grey matter. Moreover, the structural changes detected in the insula of alcohol users may reflect a reduced sensitivity to alcohol's negative subjective effects. © 2016 Society for the Study of Addiction.

Investigation of Cortical Glutamate–Glutamine and γ-Aminobutyric Acid in Obsessive–Compulsive Disorder by Proton Magnetic Resonance Spectroscopy

PubMed Central

Simpson, Helen B; Shungu, Dikoma C; Bender, James; Mao, Xiangling; Xu, Xiaoyan; Slifstein, Mark; Kegeles, Lawrence S

2012-01-01

Glutamatergic abnormalities in corticostriatal brain circuits are thought to underlie obsessive–compulsive disorder (OCD). Whether these abnormalities exist in adults with OCD is not clear. We used proton magnetic resonance spectroscopy (1H MRS) to test our hypothesis that unmedicated adults with OCD have reduced glutamate plus glutamine (Glx) levels in the medial prefrontal cortex (MPFC) compared with healthy controls. Levels of γ-aminobutyric acid (GABA) were also explored. Twenty-four unmedicated adults with OCD and 22 matched healthy control subjects underwent 1H MRS scans at 3.0 T. Resonances of both Glx and GABA were obtained using the standard J-editing technique and assessed as ratios relative to voxel tissue water (W) in the MPFC (the region of interest) and the dorsolateral prefrontal cortex (DLPFC) to explore the regional specificity of any finding. In the MPFC, Glx/W did not differ by diagnostic group (p=0.98) or sex (p=0.57). However, GABA/W was decreased in OCD (2.16±0.46 × 10−3) compared with healthy controls (2.43±0.45 × 10−3, p=0.045); moreover, age of OCD onset was inversely correlated with MPFC GABA/W (r=−0.50, p=0.015). MPFC GABA/W was higher in females than in males. In the DLPFC, there were no main effects of diagnosis or gender on Glx/W or GABA/W. These data indicate that unmedicated adults with OCD do not have Glx abnormalities in a MPFC voxel that includes the pregenual anterior cingulate cortex. However, they may have decreased MPFC GABA levels. How GABA abnormalities might contribute to corticostriatal dysfunction in OCD deserves further study. PMID:22850733

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dorogush, E S; Afonenko, A A

The distributed resonator model is used to show the presence of several resonance responses on the modulation characteristic of optically injection-locked Fabry–Perot lasers. The positions of the resonance peaks on the modulation characteristic are determined by the resonator length and frequency detuning of optical injection. It is shown that an appropriate choice of the resonator length and injection locking conditions allows one to obtain efficient modulation in two ranges near 40 – 60 GHz or to increase the direct modulation bandwidth up to 50 GHz. (control of laser radiation parameters)

Coherently-enabled environmental control of optics and energy transfer pathways of hybrid quantum dot-metallic nanoparticle systems.

PubMed

Hatef, Ali; Sadeghi, Seyed M; Fortin-Deschênes, Simon; Boulais, Etienne; Meunier, Michel

2013-03-11

It is well-known that optical properties of semiconductor quantum dots can be controlled using optical cavities or near fields of localized surface plasmon resonances (LSPRs) of metallic nanoparticles. In this paper we study the optics, energy transfer pathways, and exciton states of quantum dots when they are influenced by the near fields associated with plasmonic meta-resonances. Such resonances are formed via coherent coupling of excitons and LSPRs when the quantum dots are close to metallic nanorods and driven by a laser beam. Our results suggest an unprecedented sensitivity to the refractive index of the environment, causing significant spectral changes in the Förster resonance energy transfer from the quantum dots to the nanorods and in exciton transition energies. We demonstrate that when a quantum dot-metallic nanorod system is close to its plasmonic meta-resonance, we can adjust the refractive index to: (i) control the frequency range where the energy transfer from the quantum dot to the metallic nanorod is inhibited, (ii) manipulate the exciton transition energy shift of the quantum dot, and (iii) disengage the quantum dot from the metallic nanoparticle and laser field. Our results show that near meta-resonances the spectral forms of energy transfer and exciton energy shifts are strongly correlated to each other.

Experimental and analytical study of secondary path variations in active engine mounts

NASA Astrophysics Data System (ADS)

Hausberg, Fabian; Scheiblegger, Christian; Pfeffer, Peter; Plöchl, Manfred; Hecker, Simon; Rupp, Markus

2015-03-01

Active engine mounts (AEMs) provide an effective solution to further improve the acoustic and vibrational comfort of passenger cars. Typically, adaptive feedforward control algorithms, e.g., the filtered-x-least-mean-squares (FxLMS) algorithm, are applied to cancel disturbing engine vibrations. These algorithms require an accurate estimate of the AEM active dynamic characteristics, also known as the secondary path, in order to guarantee control performance and stability. This paper focuses on the experimental and theoretical study of secondary path variations in AEMs. The impact of three major influences, namely nonlinearity, change of preload and component temperature, on the AEM active dynamic characteristics is experimentally analyzed. The obtained test results are theoretically investigated with a linear AEM model which incorporates an appropriate description for elastomeric components. A special experimental set-up extends the model validation of the active dynamic characteristics to higher frequencies up to 400 Hz. The theoretical and experimental results show that significant secondary path variations are merely observed in the frequency range of the AEM actuator's resonance frequency. These variations mainly result from the change of the component temperature. As the stability of the algorithm is primarily affected by the actuator's resonance frequency, the findings of this paper facilitate the design of AEMs with simpler adaptive feedforward algorithms. From a practical point of view it may further be concluded that algorithmic countermeasures against instability are only necessary in the frequency range of the AEM actuator's resonance frequency.

A theory for optical wavelength control in short pulse free electron laser oscillators

NASA Astrophysics Data System (ADS)

Wilkenson, Wade F.

1993-06-01

The future safety of the U.S. Navy warship depends on the development of a directed energy self-defense system to keep pace with the ever-improving technology of anti-ship missiles. Two candidates are reviewed. The free electron laser (FEL) has the most advantages, but a chemical laser proposed by TRW is ready for installation on existing ships. Initial testing of issues related to directed energy use at sea can be conducted with the chemical laser. When the technology of the FEL matures, it can replace the chemical laser to provide the best possible defense in the shortest period of time. Continuous tunability is a key advantage of the FEL over the conventional laser. But since the output wavelength is dependent on electron energy, it is subject to random fluctuations originating from the beam source. At the Stanford University Superconducting (SCA) Free Electron Laser (FEL) Facility, the effects are minimized through negative feedback by changing the input electron energy proportional to the observed wavelength drift. The process is simulated by modifying a short pulse FEL numerical program to allow the resonant wavelength to vary over many passes. The physical effects behind optical wavelength control are explained. A theory for the preferential nature of the FEL to follow the resonant wavelength from longer to shorter wavelengths is presented. Finally, the response of the FEL to a rapidly changing resonant wavelength is displayed as a transfer function for the system.

Vibratory noise to the fingertip enhances balance improvement associated with light touch.

PubMed

Magalhães, Fernando Henrique; Kohn, André Fabio

2011-03-01

Light touch of a fingertip on an external stable surface greatly improves the postural stability of standing subjects. The hypothesis of the present work was that a vibrating surface could increase the effectiveness of fingertip signaling to the central nervous system (e.g., by a stochastic resonance mechanism) and hence improve postural stability beyond that achieved by light touch. Subjects stood quietly over a force plate while touching with their right index fingertip a surface that could be either quiescent or randomly vibrated at two low-level noise intensities. The vibratory noise of the contact surface caused a significant decrease in postural sway, as assessed by center of pressure measures in both time and frequency domains. Complementary experiments were designed to test whether postural control improvements were associated with a stochastic resonance mechanism or whether attentional mechanisms could be contributing. A full curve relating body sway parameters and different levels of vibratory noise resulted in a U-like function, suggesting that the improvement in sway relied on a stochastic resonance mechanism. Additionally, no decrease in postural sway was observed when the vibrating contact surface was attached to the subject's body, suggesting that no attentional mechanisms were involved. These results indicate that sensory cues obtained from the fingertip need not necessarily be associated with static contact surfaces to cause improvement in postural stability. A low-level noisy vibration applied to the contact surface could lead to a better performance of the postural control system.

Identification of prefrontal cortex (BA10) activation while performing Stroop test using diffuse optical tomography

NASA Astrophysics Data System (ADS)

Khadka, Sabin; Chityala, Srujan R.; Tian, Fenghua; Liu, Hanli

2011-03-01

Stroop test is commonly used as a behavior-testing tool for psychological examinations that are related to attention and cognitive control of the human brain. Studies have shown activations in Broadmann area 10 (BA10) of prefrontal cortex (PFC) during attention and cognitive process. The use of diffuse optical tomography (DOT) for human brain mapping is becoming more prevalent. In this study we expect to find neural correlates between the performed cognitive tasks and hemodynamic signals detected by a DOT system. Our initial observation showed activation of oxy-hemoglobin concentration in BA 10, which is consistent with some results seen by positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). Our study demonstrates the possibility of combining DOT with Stroop test to quantitatively investigate cognitive functions of the human brain at the prefrontal cortex.

Huygens’ Metasurfaces Enabled by Magnetic Dipole Resonance Tuning in Split Dielectric Nanoresonators

DOE PAGES

Liu, Sheng; Vaskin, Aleksandr; Campione, Salvatore; ...

2017-06-07

Dielectric metasurfaces that exploit the different Mie resonances of nanoscale dielectric resonators are a powerful platform for manipulating electromagnetic fields and can provide novel optical behavior. Here in this work, we experimentally demonstrate independent tuning of the magnetic dipole resonances relative to the electric dipole resonances of split dielectric resonators (SDRs). By increasing the split dimension, we observe a blue shift of the magnetic dipole resonance toward the electric dipole resonance. Therefore, SDRs provide the ability to directly control the interaction between the two dipole resonances within the same resonator. For example, we achieve the first Kerker condition by spectrallymore » overlapping the electric and magnetic dipole resonances and observe significantly suppressed backward scattering. Moreover, we show that a single SDR can be used as an optical nanoantenna that provides strong unidirectional emission from an electric dipole source.« less

Optical control of resonant light transmission for an atom-cavity system

NASA Astrophysics Data System (ADS)

Sharma, Arijit; Ray, Tridib; Sawant, Rahul V.; Sheikholeslami, G.; Rangwala, S. A.; Budker, D.

2015-04-01

We demonstrate the manipulation of transmitted light through an optical Fabry-Pérot cavity, built around a spectroscopy cell containing enriched rubidium vapor. Light resonant with the 87RbD2 (F =2 ,F =1 ) ↔F' manifold is controlled by the transverse intersection of the cavity mode by another resonant light beam. The cavity transmission can be suppressed or enhanced depending on the coupling of atomic states due to the intersecting beams. The extreme manifestation of the cavity-mode control is the precipitous destruction (negative logic switching) or buildup (positive logic switching) of the transmitted light intensity on intersection of the transverse control beam with the cavity mode. Both the steady-state and transient responses are experimentally investigated. The mechanism behind the change in cavity transmission is discussed in brief.

Ability of Magnetic Resonance Elastography to Assess Taut Bands

PubMed Central

Chen, Qingshan; Basford, Jeffery; An, Kai-Nan

2008-01-01

Background Myofascial taut bands are central to diagnosis of myofascial pain. Despite their importance, we still lack either a laboratory test or imaging technique capable of objectively confirming either their nature or location. This study explores the ability of magnetic resonance elastography to localize and investigate the mechanical properties of myofascial taut bands on the basis of their effects on shear wave propagation. Methods This study was conducted in three phases. The first involved the imaging of taut bands in gel phantoms, the second a finite element modeling of the phantom experiment, and the third a preliminary evaluation involving eight human subjects-four of whom had, and four of whom did not have myofascial pain. Experiments were performed with a 1.5 Tesla magnetic resonance imaging scanner. Shear wave propagation was imaged and shear stiffness was reconstructed using matched filtering stiffness inversion algorithms. Findings The gel phantom imaging and finite element calculation experiments supported our hypothesis that taut bands can be imaged based on its outstanding shear stiffness. The preliminary human study showed a statistically significant 50-100% (p=0.01) increase of shear stiffness in the taut band regions of the involved subjects relative to that of the controls or in nearby uninvolved muscle. Interpretation This study suggests that magnetic resonance elastography may have a potential for objectively characterizing myofascial taut bands that have been up to now detectable only by the clinician's fingers. PMID:18206282

Impairment of visuospatial/visuoconstructional skills in multiple sclerosis patients: the correlation with regional lesion load and subcortical atrophy.

PubMed

Marasescu, R; Cerezo Garcia, M; Aladro Benito, Y

2016-04-01

About 20% to 26% of patients with multiple sclerosis (MS) show alterations in visuospatial/visuoconstructive (VS-VC) skills even though temporo-parieto-occipital impairment is a frequent finding in magnetic resonance imaging. No studies have specifically analysed the relationship between these functions and lesion volume (LV) in these specific brain areas. To evaluate the relationship between VS-VC impairment and magnetic resonance imaging temporo-parieto-occipital LV with subcortical atrophy in patients with MS. Of 100 MS patients undergoing a routine neuropsychological evaluation, 21 were selected because they displayed VS-VC impairments in the following tests: Incomplete picture, Block design (WAIS-III), and Rey-Osterrieth complex figure test. We also selected 13 MS patients without cognitive impairment (control group). Regional LV was measured in FLAIR and T1-weighted images using a semiautomated method; subcortical atrophy was measured by bicaudate ratio and third ventricle width. Partial correlations (controlling for age and years of school) and linear regression analysis were employed to analyse correlations between magnetic resonance imaging parameters and cognitive performance. All measures of LV and brain atrophy were significantly higher in patients with cognitive impairment. Regional LV, bicaudate ratio, and third ventricle width are significantly and inversely correlated with cognitive performance; the strongest correlation was between third ventricle width and VC performance (Block design: P=.001; Rey-Osterrieth complex figure: P<.000). In the multivariate analysis, third ventricle width only had a significant effect on performance of VC tasks (Block design: P=.000; Rey-Osterrieth complex figure: P=.000), and regional FLAIR VL was linked to the VS task (Incomplete picture; P=.002). Measures of subcortical atrophy explain the variations in performance on visuocostructive tasks, and regional FLAIR VL measures are linked to VS tasks. Copyright © 2015 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.

Experimental study of the influence of different resonators on thermoacoustic conversion performance of a thermoacoustic-Stirling heat engine.

PubMed

Luo, E C; Ling, H; Dai, W; Yu, G Y

2006-12-22

In this paper, an experimental study of the effect of the resonator shape on the performance of a traveling-wave thermoacoustic engine is presented. Two different resonators were tested in the thermoacoustic-Stirling heat. One resonator is an iso-diameter one, and the other is a tapered one. To have a reasonable comparison reference, we keep the same traveling-wave loop, the same resonant frequency and the same operating pressure. The experiment showed that the resonator shape has significant influence on the global performance of the thermoacoustic-Stirling heat engine. The tapered resonator gives much better performance than the iso-diameter resonator. The tapered resonator system achieved a maximum pressure ratio of about 1.3, a maximum net acoustical power output of about 450 W and a highest thermoacoustic efficiency of about 25%.

Optical sensors based on photonic crystal: a new route

NASA Astrophysics Data System (ADS)

Romano, S.; Torino, S.; Coppola, G.; Cabrini, S.; Mocella, V.

2017-05-01

The realization of miniaturized devices able to accumulate a higher number of information in a smallest volume is a challenge of the technological development. This trend increases the request of high sensitivity and selectivity sensors which can be integrated in microsystems. In this landscape, optical sensors based on photonic crystal technology can be an appealing solution. Here, a new refractive index sensor device, based on the bound states in the continuum (BIC) resonance shift excited in a photonic crystal membrane, is presented. A microfluidic cell was used to control the injection of fluids with different refractive indices over the photonic crystal surface. The shift of very high Q-factor resonances excited into the photonic crystal open cavity was monitored as a function of the refractive index n of the test liquid. The excellent stability we found and the minimal, loss-free optical equipment requirement, provide a new route for achieving high performance in sensing applications.

Determination of Elastic Moduli of Fiber-Resin Composites Using an Impulse Excitation Technique

NASA Technical Reports Server (NTRS)

Viens, Michael J.; Johnson, Jeffrey J.

1996-01-01

The elastic moduli of graphite/epoxy and graphite/cyanate ester composite specimens with various laminate lay-ups was determined using an impulse excitation/acoustic resonance technique and compared to those determined using traditional strain gauge and extensometer techniques. The stiffness results were also compared to those predicted from laminate theory using uniaxial properties. The specimen stiffnesses interrogated ranged from 12 to 30 Msi. The impulse excitation technique was found to be a relatively quick and accurate method for determining elastic moduli with minimal specimen preparation and no requirement for mechanical loading frames. The results of this investigation showed good correlation between the elastic modulus determined using the impulse excitation technique, strain gauge and extensometer techniques, and modulus predicted from laminate theory. The flexural stiffness determined using the impulse excitation was in good agreement with that predicted from laminate theory. The impulse excitation/acoustic resonance interrogation technique has potential as a quality control test.

Towards endometriosis diagnosis by gadofosveset-trisodium enhanced magnetic resonance imaging.

PubMed

Schreinemacher, Marc H; Backes, Walter H; Slenter, Jos M; Xanthoulea, Sofia; Delvoux, Bert; van Winden, Larissa; Beets-Tan, Regina G; Evers, Johannes L H; Dunselman, Gerard A J; Romano, Andrea

2012-01-01

Endometriosis is defined as the presence of endometrial tissue outside the uterus. It affects 10-15% of women during reproductive age and has a big personal and social impact due to chronic pelvic pain, subfertility, loss of work-hours and medical costs. Such conditions are exacerbated by the fact that the correct diagnosis is made as late as 8-11 years after symptom presentation. This is due to the lack of a reliable non-invasive diagnostic test and the fact that the reference diagnostic standard is laparoscopy (invasive, expensive and not without risks). High-molecular weight gadofosveset-trisodium is used as contrast agent in Magnetic Resonance Imaging (MRI). Since it extravasates from hyperpermeable vessels more easily than from mature blood vessels, this contrast agent detects angiogenesis efficiently. Endometriosis has high angiogenic activity. Therefore, we have tested the possibility to detect endometriosis non-invasively using Dynamic Contrast-Enhanced MRI (DCE-MRI) and gadofosveset-trisodium as a contrast agent in a mouse model. Endometriotic lesions were surgically induced in nine mice by autologous transplantation. Three weeks after lesion induction, mice were scanned by DCE-MRI. Dynamic image analysis showed that the rates of uptake (inwash), persistence and outwash of the contrast agent were different between endometriosis and control tissues (large blood vessels and back muscle). Due to the extensive angiogenesis in induced lesions, the contrast agent persisted longer in endometriotic than control tissues, thus enhancing the MRI signal intensity. DCE-MRI was repeated five weeks after lesion induction, and contrast enhancement was similar to that observed three weeks after endometriosis induction. The endothelial-cell marker CD31 and the pericyte marker α-smooth-muscle-actin (mature vessels) were detected with immunohistochemistry and confirmed that endometriotic lesions had significantly higher prevalence of new vessels (CD31 only positive) than the uterus and control tissues. The diagnostic value of gadofosveset-trisodium to detect endometriosis should be tested in human settings.

Chemically etched ultrahigh-Q wedge-resonator on a silicon chip

NASA Astrophysics Data System (ADS)

Lee, Hansuek; Chen, Tong; Li, Jiang; Yang, Ki Youl; Jeon, Seokmin; Painter, Oskar; Vahala, Kerry J.

2012-06-01

Ultrahigh-Q optical resonators are being studied across a wide range of fields, including quantum information, nonlinear optics, cavity optomechanics and telecommunications. Here, we demonstrate a new resonator with a record Q-factor of 875 million for on-chip devices. The fabrication of our device avoids the requirement for a specialized processing step, which in microtoroid resonators has made it difficult to control their size and achieve millimetre- and centimetre-scale diameters. Attaining these sizes is important in applications such as microcombs and potentially also in rotation sensing. As an application of size control, stimulated Brillouin lasers incorporating our device are demonstrated. The resonators not only set a new benchmark for the Q-factor on a chip, but also provide, for the first time, full compatibility of this important device class with conventional semiconductor processing. This feature will greatly expand the range of possible `system on a chip' functions enabled by ultrahigh-Q devices.

Squeezed cooling of mechanical motion beyond the resolved-sideband limit

NASA Astrophysics Data System (ADS)

Yang, Cheng; Zhang, Lin; Zhang, Weiping

2018-04-01

Cavity optomechanics provides a unique platform for controlling micromechanical systems by means of optical fields that cross the classical-quantum boundary to achieve solid foundations for quantum technologies. Currently, optomechanical resonators have become promising candidates for the development of precisely controlled nano-motors, ultrasensitive sensors and robust quantum information processors. For all these applications, a crucial requirement is to cool the mechanical resonators down to their quantum ground states. In this paper, we present a novel cooling scheme to further cool a micromechanical resonator via the noise squeezing effect. One quadrature in such a resonator can be squeezed to induce enhanced fluctuations in the other, “heated” quadrature, which can then be used to cool the mechanical motion via conventional optomechanical coupling. Our theoretical analysis and numerical calculations demonstrate that this squeeze-and-cool mechanism offers a quick technique for deeply cooling a macroscopic mechanical resonator to an unprecedented temperature region below the zero-point fluctuations.

Modal Analysis with the Mobile Modal Testing Unit

NASA Technical Reports Server (NTRS)

Wilder, Andrew J.

2013-01-01

Recently, National Aeronautics and Space Administration's (NASA's) White Sands Test Facility (WSTF) has tested rocket engines with high pulse frequencies. This has resulted in the use of some of WSTF's existing thrust stands, which were designed for static loading, in tests with large dynamic forces. In order to ensure that the thrust stands can withstand the dynamic loading of high pulse frequency engines while still accurately reporting the test data, their vibrational modes must be characterized. If it is found that they have vibrational modes with frequencies near the pulsing frequency of the test, then they must be modified to withstand the dynamic forces from the pulsing rocket engines. To make this determination the Mobile Modal Testing Unit (MMTU), a system capable of determining the resonant frequencies and mode shapes of a structure, was used on the test stands at WSTF. Once the resonant frequency has been determined for a test stand, it can be compared to the pulse frequency of a test engine to determine whether or not that stand can avoid resonance and reliably test that engine. After analysis of test stand 406 at White Sands Test Facility, it was determined that natural frequencies for the structure are located around 75, 125, and 240 Hz, and thus should be avoided during testing.

Empathy in schizophrenia: impaired resonance.

PubMed

Haker, Helene; Rössler, Wulf

2009-09-01

Resonance is the phenomenon of one person unconsciously mirroring the motor actions as basis of emotional expressions of another person. This shared representation serves as a basis for sharing physiological and emotional states of others and is an important component of empathy. Contagious laughing and contagious yawning are examples of resonance. In the interpersonal contact with individuals with schizophrenia we can often experience impaired empathic resonance. The aim of this study is to determine differences in empathic resonance-in terms of contagion by yawning and laughing-in individuals with schizophrenia and healthy controls in the context of psychopathology and social functioning. We presented video sequences of yawning, laughing or neutral faces to 43 schizophrenia outpatients and 45 sex- and age-matched healthy controls. Participants were video-taped during the stimulation and rated regarding contagion by yawning and laughing. In addition, we assessed self-rated empathic abilities (Interpersonal Reactivity Index), psychopathology (Positive and Negative Syndrome Scale in the schizophrenia group resp. Schizotypal Personality Questionnaire in the control group), social dysfunction (Social Dysfunction Index) and executive functions (Stroop, Fluency). Individuals with schizophrenia showed lower contagion rates for yawning and laughing. Self-rated empathic concern showed no group difference and did not correlate with contagion. Low rate of contagion by laughing correlated with the schizophrenia negative syndrome and with social dysfunction. We conclude that impaired resonance is a handicap for individuals with schizophrenia in social life. Blunted observable resonance does not necessarily reflect reduced subjective empathic concern.

Hippocampal and Parahippocampal Volumes in Schizophrenia: A Structural MRI Study

PubMed Central

Sim, Kang; DeWitt, Iain; Ditman, Tali; Zalesak, Martin; Greenhouse, Ian; Goff, Donald; Weiss, Anthony P; Heckers, Stephan

2006-01-01

Smaller medial temporal lobe volume is a frequent finding in studies of patients with schizophrenia, but the relative contributions of the hippocampus and three surrounding cortical regions (entorhinal cortex, perirhinal cortex, and parahippocampal cortex) are poorly understood. We tested the hypothesis that the volumes of medial temporal lobe regions are selectively changed in schizophrenia. We studied 19 male patients with schizophrenia and 19 age-matched male control subjects. Hippocampal and cortical volumes were estimated using a three-dimensional morphometric protocol for the analysis of high-resolution structural magnetic resonance images, and repeated measures ANOVA was used to test for region-specific differences. Patients had smaller overall medial temporal lobe volumes compared to controls. The volume difference was not specific for either region or hemisphere. The finding of smaller medial temporal lobe volumes in the absence of regional specificity has important implications for studying the functional role of the hippocampus and surrounding cortical regions in schizophrenia. PMID:16319377

Evaluation of Enhanced Attention to Local Detail in Anorexia Nervosa Using the Embedded Figures Test; an fMRI Study

PubMed Central

Giampietro, Vincent; Van den Eynde, Frederique; Davies, Helen; Lounes, Naima; Andrew, Christopher; Dalton, Jeffrey; Simmons, Andrew; Williams, Steven C.R.; Baron-Cohen, Simon; Tchanturia, Kate

2013-01-01

The behavioural literature in anorexia nervosa and autism spectrum disorders has indicated an overlap in cognitive profiles. One such domain is the enhancement of local processing over global processing. While functional imaging studies of autism spectrum disorder have revealed differential neural patterns compared to controls in response to tests of local versus global processing, no studies have explored such effects in anorexia nervosa. This study uses functional magnetic resonance imaging in conjunction with the embedded figures test, to explore the neural correlates of this enhanced attention to detail in the largest anorexia nervosa cohort to date. On the embedded figures tests participants are required to indicate which of two complex figures contains a simple geometrical shape. The findings indicate that whilst healthy controls showed greater accuracy on the task than people with anorexia nervosa, different brain regions were recruited. Healthy controls showed greater activation in the precuneus whilst people with anorexia nervosa showed greater activation in the fusiform gyrus. This suggests that different cognitive strategies were used to perform the task, i.e. healthy controls demonstrated greater emphasis on visuospatial searching and people with anorexia nervosa employed a more object recognition-based approach. This is in accordance with previous findings in autism spectrum disorder using a similar methodology and has implications for therapies addressing the appropriate adjustment of cognitive strategies in anorexia nervosa. PMID:23691129

Evaluation of enhanced attention to local detail in anorexia nervosa using the embedded figures test; an FMRI study.

PubMed

Fonville, Leon; Lao-Kaim, Nick P; Giampietro, Vincent; Van den Eynde, Frederique; Davies, Helen; Lounes, Naima; Andrew, Christopher; Dalton, Jeffrey; Simmons, Andrew; Williams, Steven C R; Baron-Cohen, Simon; Tchanturia, Kate

2013-01-01

The behavioural literature in anorexia nervosa and autism spectrum disorders has indicated an overlap in cognitive profiles. One such domain is the enhancement of local processing over global processing. While functional imaging studies of autism spectrum disorder have revealed differential neural patterns compared to controls in response to tests of local versus global processing, no studies have explored such effects in anorexia nervosa. This study uses functional magnetic resonance imaging in conjunction with the embedded figures test, to explore the neural correlates of this enhanced attention to detail in the largest anorexia nervosa cohort to date. On the embedded figures tests participants are required to indicate which of two complex figures contains a simple geometrical shape. The findings indicate that whilst healthy controls showed greater accuracy on the task than people with anorexia nervosa, different brain regions were recruited. Healthy controls showed greater activation in the precuneus whilst people with anorexia nervosa showed greater activation in the fusiform gyrus. This suggests that different cognitive strategies were used to perform the task, i.e. healthy controls demonstrated greater emphasis on visuospatial searching and people with anorexia nervosa employed a more object recognition-based approach. This is in accordance with previous findings in autism spectrum disorder using a similar methodology and has implications for therapies addressing the appropriate adjustment of cognitive strategies in anorexia nervosa.

Diagnostic value of T1 and T2 * relaxation times and off-resonance saturation effects in the evaluation of Achilles tendinopathy by MRI at 3T.

PubMed

Grosse, Ulrich; Syha, Roland; Hein, Tobias; Gatidis, Sergios; Grözinger, Gerd; Schabel, Christoph; Martirosian, Petros; Schick, Fritz; Springer, Fabian

2015-04-01

To evaluate and compare the diagnostic value of T1 , T2 * relaxation times and off-resonance saturation ratios (OSR) in healthy controls and patients with different clinical and morphological stages of Achilles tendinopathy. Forty-two healthy Achilles tendons and 34 tendons of 17 patients with symptomatic and asymptomatic tendinopathy were investigated clinically with conventional magnetic resonance imaging (MRI) sequences on a 3T whole-body MR scanner and a dynamic ultrasound examination. In addition, T1 and T2 * relaxation times were assessed using an ultrashort echo time (UTE) imaging sequence with flip angle and echo time variation. For the calculation of OSR values a Gaussian off-resonance saturation pulse (frequency offset: 750-5000 Hz) was used. The diagnostic value of the derived MR values was assessed and compared using receiver operating characteristic (ROC) curves. ROC curves demonstrate the highest overall test performance for OSR values at 2000 Hz off-resonance in differentiating slightly (OSR-2000 [AUC: 0.930] > T2 * [AUC: 0.884] > T1 [AUC: 0.737]) and more severe pathologically altered tendon areas (OSR-2000 [AUC: 0.964] > T2 * [AUC: 0.917] > T1 [AUC: 0.819]) from healthy ones. OSR values at a frequency offset of 2000 Hz demonstrated a better sensitivity and specificity for detecting mild and severe stages of tendinopathy compared to T2 * and particularly when compared to T1 relaxation times. © 2014 Wiley Periodicals, Inc.

Fabrication of vertical nanowire resonators for aerosol exposure assessment

NASA Astrophysics Data System (ADS)

Merzsch, Stephan; Wasisto, Hutomo Suryo; Stranz, Andrej; Hinze, Peter; Weimann, Thomas; Peiner, Erwin; Waag, Andreas

2013-05-01

Vertical silicon nanowire (SiNW) resonators are designed and fabricated in order to assess exposure to aerosol nanoparticles (NPs). To realize SiNW arrays, nanolithography and inductively coupled plasma (ICP) deep reactive ion etching (DRIE) at cryogenic temperature are utilized in a top-down fabrication of SiNW arrays which have high aspect ratios (i.e., up to 34). For nanolithography process, a resist film thickness of 350 nm is applied in a vacuum contact mode to serve as a mask. A pattern including various diameters and distances for creating pillars is used (i.e., 400 nm up to 5 μm). In dry etching process, the etch rate is set high of 1.5 μm/min to avoid underetching. The etch profiles of Si wires can be controlled aiming to have either perpendicularly, negatively or positively profiled sidewalls by adjusting the etching parameters (e.g., temperature and oxygen content). Moreover, to further miniaturize the wire, multiple sacrificial thermal oxidations and subsequent oxide stripping are used yielding SiNW arrays of 650 nm in diameter and 40 μm in length. In the resonant frequency test, a piezoelectric shear actuator is integrated with the SiNWs inside a scanning electron microscope (SEM) chamber. The observation of the SiNW deflections are performed and viewed from the topside of the SiNWs to reduce the measurement redundancy. Having a high deflection of ~10 μm during its resonant frequency of 452 kHz and a low mass of 31 pg, the proposed SiNW is potential for assisting the development of a portable aerosol resonant sensor.

Voltage-controlled spin selection in a magnetic resonant tunneling diode.

PubMed

Slobodskyy, A; Gould, C; Slobodskyy, T; Becker, C R; Schmidt, G; Molenkamp, L W

2003-06-20

We have fabricated all II-VI semiconductor resonant tunneling diodes based on the (Zn,Mn,Be)Se material system, containing dilute magnetic material in the quantum well, and studied their current-voltage characteristics. When subjected to an external magnetic field the resulting spin splitting of the levels in the quantum well leads to a splitting of the transmission resonance into two separate peaks. This is interpreted as evidence of tunneling transport through spin polarized levels, and could be the first step towards a voltage controlled spin filter.

Magnetic-field-mediated coupling and control in hybrid atomic-nanomechanical systems

NASA Astrophysics Data System (ADS)

Tretiakov, A.; LeBlanc, L. J.

2016-10-01

Magnetically coupled hybrid quantum systems enable robust quantum state control through Landau-Zener transitions. Here, we show that an ultracold atomic sample magnetically coupled to a nanomechanical resonator can be used to cool the resonator's mechanical motion, to measure the mechanical temperature, and to enable entanglement of more than one of these mesoscopic objects. We calculate the expected coupling for both permanent-magnet and current-conducting nanostring resonators and describe how this hybridization is attainable using recently developed fabrication techniques, including SiN nanostrings and atom chips.

Optical filter having coupled whispering-gallery-mode resonators

NASA Technical Reports Server (NTRS)

Savchenkov, Anatoliy (Inventor); Ilchenko, Vladimir (Inventor); Maleki, Lutfollah (Inventor); Handley, Timothy A. (Inventor)

2006-01-01

Optical filters having at least two coupled whispering-gallery-mode (WGM) optical resonators to produce a second order or higher order filter function with a desired spectral profile. At least one of the coupled WGM optical resonators may be tunable by a control signal to adjust the filtering function.

Smart Sensing and Dynamic Fitting for Enhanced Comfort and Performance of Prosthetics

DTIC Science & Technology

2017-10-01

studying microstrip resonators for bio- impedance measurement. For actuation, we have 1) improved and de -bugged the prosthetic interface control ...studying microstrip resonators for bio‐impedance measurement. For actuation, we have 1) improved and de -bugged the prosthetic interface control ...shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number

Resonant interaction of the electron beam with a synchronous wave in controlled magnetrons for high-current superconducting accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kazakevich, G.; Johnson, R.; Lebedev, V.

A simplified analytical model of the resonant interaction of the beam of Larmor electrons drifting in the crossed constant fields of a magnetron with a synchronous wave providing a phase grouping of the drifting charge was developed to optimize the parameters of an rf resonant injected signal driving the magnetrons for management of phase and power of rf sources with a rate required for superconducting high-current accelerators. The model, which considers the impact of the rf resonant signal injected into the magnetron on the operation of the injection-locked tube, substantiates the recently developed method of fast power control of magnetronsmore » in the range up to 10 dB at the highest generation efficiency, with low noise, precise stability of the carrier frequency, and the possibility of wideband phase control. Experiments with continuous wave 2.45 GHz, 1 kW microwave oven magnetrons have verified the correspondence of the behavior of these tubes to the analytical model. A proof of the principle of the novel method of power control in magnetrons, based on the developed model, was demonstrated in the experiments. The method is attractive for high-current superconducting rf accelerators. This study also discusses vector methods of power control with the rates required for superconducting accelerators, the impact of the rf resonant signal injected into the magnetron on the rate of phase control of the injection-locked tubes, and a conceptual scheme of the magnetron transmitter with highest efficiency for high-current accelerators.« less

Resonant interaction of the electron beam with a synchronous wave in controlled magnetrons for high-current superconducting accelerators

DOE PAGES

Kazakevich, G.; Johnson, R.; Lebedev, V.; ...

2018-06-14

A simplified analytical model of the resonant interaction of the beam of Larmor electrons drifting in the crossed constant fields of a magnetron with a synchronous wave providing a phase grouping of the drifting charge was developed to optimize the parameters of an rf resonant injected signal driving the magnetrons for management of phase and power of rf sources with a rate required for superconducting high-current accelerators. The model, which considers the impact of the rf resonant signal injected into the magnetron on the operation of the injection-locked tube, substantiates the recently developed method of fast power control of magnetronsmore » in the range up to 10 dB at the highest generation efficiency, with low noise, precise stability of the carrier frequency, and the possibility of wideband phase control. Experiments with continuous wave 2.45 GHz, 1 kW microwave oven magnetrons have verified the correspondence of the behavior of these tubes to the analytical model. A proof of the principle of the novel method of power control in magnetrons, based on the developed model, was demonstrated in the experiments. The method is attractive for high-current superconducting rf accelerators. This study also discusses vector methods of power control with the rates required for superconducting accelerators, the impact of the rf resonant signal injected into the magnetron on the rate of phase control of the injection-locked tubes, and a conceptual scheme of the magnetron transmitter with highest efficiency for high-current accelerators.« less

Electric-optic resonant phase modulator

NASA Technical Reports Server (NTRS)

Chen, Chien-Chung (Inventor); Robinson, Deborah L. (Inventor); Hemmati, Hamid (Inventor)

1994-01-01

An electro-optic resonant cavity is used to achieve phase modulation with lower driving voltages. Laser damage thresholds are inherently higher than with previously used integrated optics due to the utilization of bulk optics. Phase modulation is achieved at higher speeds with lower driving voltages than previously obtained with non-resonant electro-optic phase modulators. The instant scheme uses a data locking dither approach as opposed to the conventional sinusoidal locking schemes. In accordance with a disclosed embodiment, a resonant cavity modulator has been designed to operate at a data rate in excess of 100 Mbps. By carefully choosing the cavity finesse and its dimension, it is possible to control the pulse switching time to within 4 ns and to limit the required switching voltage to within 10 V. Experimentally, the resonant cavity can be maintained on resonance with respect to the input laser signal by monitoring the fluctuation of output intensity as the cavity is switched. This cavity locking scheme can be applied by using only the random data sequence, and without the need of additional dithering of the cavity. Compared to waveguide modulators, the resonant cavity has a comparable modulating voltage requirement. Because of its bulk geometry, resonant cavity modulator has the potential of accommodating higher throughput power. Furthermore, mode matching into a bulk device is easier and typically can be achieved with higher efficiency. On the other hand, unlike waveguide modulators which are essentially traveling wave devices, the resonant cavity modulator requires that the cavity be maintained in resonance with respect to the incoming laser signal. An additional control loop is incorporated into the modulator to maintain the cavity on resonance.

Ultraviolet resonance Raman spectroscopy for the detection of cocaine in oral fluid

NASA Astrophysics Data System (ADS)

D'Elia, Valentina; Montalvo, Gemma; Ruiz, Carmen García; Ermolenkov, Vladimir V.; Ahmed, Yasmine; Lednev, Igor K.

2018-01-01

Detecting and quantifying cocaine in oral fluid is of significant importance for practical forensics. Up to date, mainly destructive methods or biochemical tests have been used, while spectroscopic methods were only applied to pretreated samples. In this work, the possibility of using resonance Raman spectroscopy to detect cocaine in oral fluid without pretreating samples was tested. It was found that ultraviolet resonance Raman spectroscopy with 239-nm excitation allows for the detection of cocaine in oral fluid at 10 μg/mL level. Further method development will be needed for reaching the practically useful levels of cocaine detection.

Calibration, Monitoring, and Control of Complex Detector Systems

NASA Astrophysics Data System (ADS)

Breidenbach, M.

1981-04-01

LEP Detectors will probably be complex devices having tens of subsystems; some subsystems having perhaps tens of thousands of channels. Reasonable design goals for such a detector will include economic use of money and people, rapid and reliable calibration and monitoring of the detector, and simple control and operation of the device. The synchronous operation of an e+e- storage ring, coupled with its relatively low interaction rate, allow the design of simple circuits for time and charge measurements. These circuits, and more importantly, the basic detector channels, can usually be tested and calibrated by signal injection into the detector. Present detectors utilize semi-autonomous controllers which collect such calibration data and calculate statistics as well as control sparse data scans. Straightforward improvements in programming technology should move the entire calibration into these local controllers, so that calibration and testing time will be a constant independent of the number of channels in a system. Considerable programming effort may be saved by emphasizing the similarities of the subsystems, so that the subsystems can be described by a reasonable database and general purpose calibration and test routines can be used. Monitoring of the apparatus will probably continue to be of two classes: "passive" histogramming of channel occupancies and other more complex combinations of the data; and "active" injection of test patterns and calibration signals during a run. The relative importance of active monitoring will increase for the low data rates expected off resonances at high s. Experience at SPEAR and PEP is used to illustrate these approaches.

The diagnostic test accuracy of magnetic resonance imaging, magnetic resonance arthrography and computer tomography in the detection of chondral lesions of the hip.

PubMed

Smith, Toby O; Simpson, Michael; Ejindu, Vivian; Hing, Caroline B

2013-04-01

The purpose of this study was to assess the diagnostic test accuracy of magnetic resonance imaging (MRI), magnetic resonance arthrography (MRA) and multidetector arrays in CT arthrography (MDCT) for assessing chondral lesions in the hip joint. A review of the published and unpublished literature databases was performed to identify all studies reporting the diagnostic test accuracy (sensitivity/specificity) of MRI, MRA or MDCT for the assessment of adults with chondral (cartilage) lesions of the hip with surgical comparison (arthroscopic or open) as the reference test. All included studies were reviewed using the quality assessment of diagnostic accuracy studies appraisal tool. Pooled sensitivity, specificity, likelihood ratios and diagnostic odds ratios were calculated with 95 % confidence intervals using a random-effects meta-analysis for MRI, MRA and MDCT imaging. Eighteen studies satisfied the eligibility criteria. These included 648 hips from 637 patients. MRI indicated a pooled sensitivity of 0.59 (95 % CI: 0.49-0.70) and specificity of 0.94 (95 % CI: 0.90-0.97), and MRA sensitivity and specificity values were 0.62 (95 % CI: 0.57-0.66) and 0.86 (95 % CI: 0.83-0.89), respectively. The diagnostic test accuracy for the detection of hip joint cartilage lesions is currently superior for MRI compared with MRA. There were insufficient data to perform meta-analysis for MDCT or CTA protocols. Based on the current limited diagnostic test accuracy of the use of magnetic resonance or CT, arthroscopy remains the most accurate method of assessing chondral lesions in the hip joint.

Magnetic resonance imaging reveals altered distribution of hepatic fat in children with type 1 diabetes compared to controls.

PubMed

Regnell, Simon E; Peterson, Pernilla; Trinh, Lena; Broberg, Per; Leander, Peter; Lernmark, Åke; Månsson, Sven; Elding Larsson, Helena

2015-08-01

Children with type 1 diabetes have been identified as a risk group for non-alcoholic fatty liver disease (NAFLD). The aim was to compare total hepatic fat fraction and fat distribution across Couinaud segments in children with type 1 diabetes and controls and the relation of hepatic fat to plasma and anthropometric parameters. Hepatic fat fraction and fat distribution across Couinaud segments were measured with magnetic resonance imaging (MRI) in 22 children with type 1 diabetes and 32 controls. Blood tests and anthropometric data were collected. No children had NAFLD. Children with type 1 diabetes had a slightly lower hepatic fat fraction (median 1.3%) than controls (median 1.8%), and their fat had a different segmental distribution. The fat fraction of segment V was the most representative of the liver as a whole. An incidental finding was that diabetes patients treated with multiple daily injections of insulin (MDI) had a fat distribution more similar to controls than patients with continuous subcutaneous insulin infusion (CSII). In children with type 1 diabetes, NAFLD may be less common than recent studies have suggested. Children with type 1 diabetes may have a lower fat fraction and a different fat distribution in the liver than controls. Diabetes treatment with MDI or CSII may affect liver fat, but this needs to be confirmed in a larger sample of patients. The heterogeneity of hepatic fat infiltration may affect results when liver biopsy is used for diagnosing fatty liver. Copyright © 2015 Elsevier Inc. All rights reserved.

Generation of tunable double Fano resonances by plasmon hybridization in graphene–metal metamaterial

NASA Astrophysics Data System (ADS)

Yan, Zhendong; Qian, Lina; Zhan, Peng; Wang, Zhenlin

2018-07-01

We proposed the excitation of double Fano resonances by the destructive interference between the narrow electric symmetric/antisymmetric resonant modes formed by plasmon hybridization and a broad magnetic dipole resonance in a novel hybrid metamaterial composed of periodically patterned stacked graphene–ribbon pairs and gold split-ring resonators. The double Fano transparency windows in this hybrid metamaterial can be actively controlled by tuning the Fermi energy of graphene through the use of electric gating and its electronic mobility. Our designed dual Fano resonances exhibit a large group index associated with the resonance response in the transparency windows, suggesting promising applications in nanophotonics, such as a slow light device.

Reliability of Task-Based fMRI for Preoperative Planning: A Test-Retest Study in Brain Tumor Patients and Healthy Controls

PubMed Central

Morrison, Melanie A.; Churchill, Nathan W.; Cusimano, Michael D.; Schweizer, Tom A.; Das, Sunit; Graham, Simon J.

2016-01-01

Background Functional magnetic resonance imaging (fMRI) continues to develop as a clinical tool for patients with brain cancer, offering data that may directly influence surgical decisions. Unfortunately, routine integration of preoperative fMRI has been limited by concerns about reliability. Many pertinent studies have been undertaken involving healthy controls, but work involving brain tumor patients has been limited. To develop fMRI fully as a clinical tool, it will be critical to examine these reliability issues among patients with brain tumors. The present work is the first to extensively characterize differences in activation map quality between brain tumor patients and healthy controls, including the effects of tumor grade and the chosen behavioral testing paradigm on reliability outcomes. Method Test-retest data were collected for a group of low-grade (n = 6) and high-grade glioma (n = 6) patients, and for matched healthy controls (n = 12), who performed motor and language tasks during a single fMRI session. Reliability was characterized by the spatial overlap and displacement of brain activity clusters, BOLD signal stability, and the laterality index. Significance testing was performed to assess differences in reliability between the patients and controls, and low-grade and high-grade patients; as well as between different fMRI testing paradigms. Results There were few significant differences in fMRI reliability measures between patients and controls. Reliability was significantly lower when comparing high-grade tumor patients to controls, or to low-grade tumor patients. The motor task produced more reliable activation patterns than the language tasks, as did the rhyming task in comparison to the phonemic fluency task. Conclusion In low-grade glioma patients, fMRI data are as reliable as healthy control subjects. For high-grade glioma patients, further investigation is required to determine the underlying causes of reduced reliability. To maximize reliability outcomes, testing paradigms should be carefully selected to generate robust activation patterns. PMID:26894279

Controlling the gain contribution of background emitters in few-quantum-dot microlasers

NASA Astrophysics Data System (ADS)

Gericke, F.; Segnon, M.; von Helversen, M.; Hopfmann, C.; Heindel, T.; Schneider, C.; Höfling, S.; Kamp, M.; Musiał, A.; Porte, X.; Gies, C.; Reitzenstein, S.

2018-02-01

We provide experimental and theoretical insight into single-emitter lasing effects in a quantum dot (QD)-microlaser under controlled variation of background gain provided by off-resonant discrete gain centers. For that purpose, we apply an advanced two-color excitation concept where the background gain contribution of off-resonant QDs can be continuously tuned by precisely balancing the relative excitation power of two lasers emitting at different wavelengths. In this way, by selectively exciting a single resonant QD and off-resonant QDs, we identify distinct single-QD signatures in the lasing characteristics and distinguish between gain contributions of a single resonant emitter and a countable number of off-resonant background emitters to the optical output of the microlaser. Our work addresses the important question whether single-QD lasing is feasible in experimentally accessible systems and shows that, for the investigated microlaser, the single-QD gain needs to be supported by the background gain contribution of off-resonant QDs to reach the transition to lasing. Interestingly, while a single QD cannot drive the investigated micropillar into lasing, its relative contribution to the emission can be as high as 70% and it dominates the statistics of emitted photons in the intermediate excitation regime below threshold.

Dynamic control modification techniques in teleoperation of a flexible manipulator. M.S. Thesis

NASA Technical Reports Server (NTRS)

Magee, David Patrick

1991-01-01

The objective of this research is to reduce the end-point vibration of a large, teleoperated manipulator while preserving the usefulness of the system motion. A master arm is designed to measure desired joint angles as the user specifies a desired tip motion. The desired joint angles from the master arm are the inputs to an adaptive PD control algorithm that positions the end-point of the manipulator. As the user moves the tip of the master, the robot will vibrate at its natural frequencies which makes it difficult to position the end-point. To eliminate the tip vibration during teleoperated motions, an input shaping method is presented. The input shaping method transforms each sample of the desired input into a new set of impulses that do not excite the system resonances. The method is explained using the equation of motion for a simple, second-order system. The impulse response of such a system is derived and the constraint equations for vibrationless motion are presented. To evaluate the robustness of the method, a different residual vibration equation from Singer's is derived that more accurately represents the input shaping technique. The input shaping method is shown to actually increase the residual vibration in certain situations when the system parameters are not accurately specified. Finally, the implementation of the input shaping method to a system with varying parameters is shown to induce a vibration into the system. To eliminate this vibration, a modified command shaping technique is developed. The ability of the modified command shaping method to reduce vibration at the system resonances is tested by varying input perturbations to trajectories in a range of possible user inputs. By comparing the frequency responses of the transverse acceleration at the end-point of the manipulator, the modified method is compared to the original PD routine. The control scheme that produces the smaller magnitude of resonant vibration at the first natural frequency is considered the more effective control method.

Amide proton transfer magnetic resonance imaging of Alzheimer's disease at 3.0 Tesla: a preliminary study.

PubMed

Wang, Rui; Li, Sa-Ying; Chen, Min; Zhou, Jin-Yuan; Peng, Dan-Tao; Zhang, Chen; Dai, Yong-Ming

2015-03-05

Amide proton transfer (APT) imaging has recently emerged as an important contrast mechanism for magnetic resonance imaging (MRI) in the field of molecular and cellular imaging. The aim of this study was to evaluate the feasibility of APT imaging to detect cerebral abnormality in patients with Alzheimer's disease (AD) at 3.0 Tesla. Twenty AD patients (9 men and 11 women; age range, 67-83 years) and 20 age-matched normal controls (11 men and 9 women; age range, 63-82 years) underwent APT and traditional MRI examination on a 3.0 Tesla MRI system. The magnetic resonance ratio asymmetry (MTR asym ) values at 3.5 ppm of bilateral hippocampi (Hc), temporal white matter regions, occipital white matter regions, and cerebral peduncles were measured on oblique axial APT images. MTR asym (3.5 ppm) values of the cerebral structures between AD patients and control subjects were compared with independent samples t-test. Controlling for age, partial correlation analysis was used to investigate the associations between mini-mental state examination (MMSE) and the various MRI measures among AD patients. Compared with normal controls, MTR asym (3.5 ppm) values of bilateral Hc were significantly increased in AD patients (right 1.24% ± 0.21% vs. 0.83% ± 0.19%, left 1.18% ± 0.18% vs. 0.80%± 0.17%, t = 3.039, 3.328, P = 0.004, 0.002, respectively). MTR asym (3.5 ppm) values of bilateral Hc were significantly negatively correlated with MMSE (right r = -0.559, P = 0.013; left r = -0.461, P = 0.047). Increased MTR asym (3.5 ppm) values of bilateral Hc in AD patients and its strong correlations with MMSE suggest that APT imaging could potentially provide imaging biomarkers for the noninvasive molecular diagnosis of AD.

Right and Left Ventricular Function and Mass in Male Elite Master Athletes: A Controlled Contrast-Enhanced Cardiovascular Magnetic Resonance Study.

PubMed

Bohm, Philipp; Schneider, Günther; Linneweber, Lutz; Rentzsch, Axel; Krämer, Nadine; Abdul-Khaliq, Hashim; Kindermann, Wilfried; Meyer, Tim; Scharhag, Jürgen

2016-05-17

It is under debate whether the cumulative effects of intensive endurance exercise induce chronic cardiac damage, mainly involving the right heart. The aim of this study was to examine the cardiac structure and function in long-term elite master endurance athletes with special focus on the right ventricle by contrast-enhanced cardiovascular magnetic resonance. Thirty-three healthy white competitive elite male master endurance athletes (age range, 30-60 years) with a training history of 29±8 years, and 33 white control subjects pair-matched for age, height, and weight underwent cardiopulmonary exercise testing, echocardiography including tissue-Doppler imaging and speckle tracking, and cardiovascular magnetic resonance. Indexed left ventricular mass and right ventricular mass (left ventricular mass/body surface area, 96±13 and 62±10 g/m(2); P<0.001; right ventricular mass/body surface area, 36±7 and 24±5 g/m(2); P<0.001) and indexed left ventricular end-diastolic volume and right ventricular end-diastolic volume (left ventricular end-diastolic volume/body surface area, 104±13 and 69±18 mL/m(2); P<0.001; right ventricular end-diastolic volume/body surface area, 110±22 and 66±16 mL/m(2); P<0.001) were significantly increased in athletes in comparison with control subjects. Right ventricular ejection fraction did not differ between athletes and control subjects (52±8 and 54±6%; P=0.26). Pathological late enhancement was detected in 1 athlete. No correlations were found for left ventricular and right ventricular volumes and ejection fraction with N-terminal pro-brain natriuretic peptide, and high-sensitive troponin was negative in all subjects. Based on our results, chronic right ventricular damage in elite endurance master athletes with lifelong high training volumes seems to be unlikely. Thus, the hypothesis of an exercise-induced arrhythmogenic right ventricular cardiomyopathy has to be questioned. © 2016 American Heart Association, Inc.

Modeling and Simulation of a Parametrically Resonant Micromirror With Duty-Cycled Excitation

PubMed Central

Shahid, Wajiha; Qiu, Zhen; Duan, Xiyu; Li, Haijun; Wang, Thomas D.; Oldham, Kenn R.

2014-01-01

High frequency large scanning angle electrostatically actuated microelectromechanical systems (MEMS) mirrors are used in a variety of applications involving fast optical scanning. A 1-D parametrically resonant torsional micromirror for use in biomedical imaging is analyzed here with respect to operation by duty-cycled square waves. Duty-cycled square wave excitation can have significant advantages for practical mirror regulation and/or control. The mirror’s nonlinear dynamics under such excitation is analyzed in a Hill’s equation form. This form is used to predict stability regions (the voltage-frequency relationship) of parametric resonance behavior over large scanning angles using iterative approximations for nonlinear capacitance behavior of the mirror. Numerical simulations are also performed to obtain the mirror’s frequency response over several voltages for various duty cycles. Frequency sweeps, stability results, and duty cycle trends from both analytical and simulation methods are compared with experimental results. Both analytical models and simulations show good agreement with experimental results over the range of duty cycled excitations tested. This paper discusses the implications of changing amplitude and phase with duty cycle for robust open-loop operation and future closed-loop operating strategies. PMID:25506188

Analysis of 3-D Tongue Motion From Tagged and Cine Magnetic Resonance Images

PubMed Central

Woo, Jonghye; Lee, Junghoon; Murano, Emi Z.; Stone, Maureen; Prince, Jerry L.

2016-01-01

Purpose Measuring tongue deformation and internal muscle motion during speech has been a challenging task because the tongue deforms in 3 dimensions, contains interdigitated muscles, and is largely hidden within the vocal tract. In this article, a new method is proposed to analyze tagged and cine magnetic resonance images of the tongue during speech in order to estimate 3-dimensional tissue displacement and deformation over time. Method The method involves computing 2-dimensional motion components using a standard tag-processing method called harmonic phase, constructing superresolution tongue volumes using cine magnetic resonance images, segmenting the tongue region using a random-walker algorithm, and estimating 3-dimensional tongue motion using an incompressible deformation estimation algorithm. Results Evaluation of the method is presented with a control group and a group of people who had received a glossectomy carrying out a speech task. A 2-step principal-components analysis is then used to reveal the unique motion patterns of the subjects. Azimuth motion angles and motion on the mirrored hemi-tongues are analyzed. Conclusion Tests of the method with a various collection of subjects show its capability of capturing patient motion patterns and indicate its potential value in future speech studies. PMID:27295428

Design and fabrication of prototype system for early warning of impending bearing failure

NASA Technical Reports Server (NTRS)

Meacher, J.; Chen, H. M.

1974-01-01

A test program was conducted with the objective of developing a method and equipment for on-line monitoring of installed ball bearings to detect deterioration or impending failure of the bearings. The program was directed at the spin-axis bearings of a control moment gyro. The bearings were tested at speeds of 6000 and 8000 rpm, thrust loads from 50 to 1000 pounds, with a wide range of lubrication conditions, with and without a simulated fatigue spall implanted in the inner race ball track. It was concluded that a bearing monitor system based on detection and analysis of modulations of a fault indicating bearing resonance frequency can provide a low threshold of sensitivity.

Low-frequency noise reduction of lightweight airframe structures

NASA Technical Reports Server (NTRS)

Getline, G. L.

1976-01-01

The results of an experimental study to determine the noise attenuation characteristics of aircraft type fuselage structural panels were presented. Of particular interest was noise attenuation at low frequencies, below the fundamental resonances of the panels. All panels were flightweight structures for transport type aircraft in the 34,050 to 45,400 kg (75,000 to 100,000 pounds) gross weight range. Test data include the results of vibration and acoustic transmission loss tests on seven types of isotropic and orthotropically stiffened, flat and curved panels. The results show that stiffness controlled acoustically integrated structures can provide very high noise reductions at low frequencies without significantly affecting their high frequency noise reduction capabilities.

Separating hyperfine from spin-orbit interactions in organic semiconductors by multi-octave magnetic resonance using coplanar waveguide microresonators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joshi, G.; Miller, R.; Ogden, L.

2016-09-05

Separating the influence of hyperfine from spin-orbit interactions in spin-dependent carrier recombination and dissociation processes necessitates magnetic resonance spectroscopy over a wide range of frequencies. We have designed compact and versatile coplanar waveguide resonators for continuous-wave electrically detected magnetic resonance and tested these on organic light-emitting diodes. By exploiting both the fundamental and higher-harmonic modes of the resonators, we cover almost five octaves in resonance frequency within a single setup. The measurements with a common π-conjugated polymer as the active material reveal small but non-negligible effects of spin-orbit interactions, which give rise to a broadening of the magnetic resonance spectrummore » with increasing frequency.« less

Strongly Coupled Nanotube Electromechanical Resonators.

PubMed

Deng, Guang-Wei; Zhu, Dong; Wang, Xin-He; Zou, Chang-Ling; Wang, Jiang-Tao; Li, Hai-Ou; Cao, Gang; Liu, Di; Li, Yan; Xiao, Ming; Guo, Guang-Can; Jiang, Kai-Li; Dai, Xing-Can; Guo, Guo-Ping

2016-09-14

Coupling an electromechanical resonator with carbon-nanotube quantum dots is a significant method to control both the electronic charge and the spin quantum states. By exploiting a novel microtransfer technique, we fabricate two separate strongly coupled and electrically tunable mechanical resonators for the first time. The frequency of the two resonators can be individually tuned by the bottom gates, and in each resonator, the electron transport through the quantum dot can be strongly affected by the phonon mode and vice versa. Furthermore, the conductance of either resonator can be nonlocally modulated by the other resonator through phonon-phonon interaction between the two resonators. Strong coupling is observed between the phonon modes of the two resonators, where the coupling strength larger than 200 kHz can be reached. This strongly coupled nanotube electromechanical resonator array provides an experimental platform for future studies of the coherent electron-phonon interaction, the phonon-mediated long-distance electron interaction, and entanglement state generation.

Development of in-series piezoelectric bimorph bending beam actuators for active flow control applications

NASA Astrophysics Data System (ADS)

Chan, Wilfred K.; Clingman, Dan J.; Amitay, Michael

2016-04-01

Piezoelectric materials have long been used for active flow control purposes in aerospace applications to increase the effectiveness of aerodynamic surfaces on aircraft, wind turbines, and more. Piezoelectric actuators are an appropriate choice due to their low mass, small dimensions, simplistic design, and frequency response. This investigation involves the development of piezoceramic-based actuators with two bimorphs placed in series. Here, the main desired characteristic was the achievable displacement amplitude at specific driving voltages and frequencies. A parametric study was performed, in which actuators with varying dimensions were fabricated and tested. These devices were actuated with a sinusoidal waveform, resulting in an oscillating platform on which to mount active flow control devices, such as dynamic vortex generators. The main quantification method consisted of driving these devices with different voltages and frequencies to determine their free displacement, blocking force, and frequency response. It was found that resonance frequency increased with shorter and thicker actuators, while free displacement increased with longer and thinner actuators. Integration of the devices into active flow control test modules is noted. In addition to physical testing, a quasi-static analytical model was developed and compared with experimental data, which showed close correlation for both free displacement and blocking force.

Magnetic resonance conditional paramagnetic choke for suppression of imaging artifacts during magnetic resonance imaging.

PubMed

Wu, Kevin J; Gregory, T Stan; Boland, Brian L; Zhao, Wujun; Cheng, Rui; Mao, Leidong; Tse, Zion Tsz Ho

2018-06-01

Higher risk patient populations require continuous physiological monitoring and, in some cases, connected life-support systems, during magnetic resonance imaging examinations. While recently there has been a shift toward wireless technology, some of the magnetic resonance imaging devices are still connected to the outside using cabling that could interfere with the magnetic resonance imaging's radio frequency during scanning, resulting in excessive heating. We developed a passive method for radio frequency suppression on cabling that may assist in making some of these devices magnetic resonance imaging compatible. A barrel-shaped strongly paramagnetic choke was developed to suppress induced radio frequency signals which are overlaid onto physiological monitoring leads during magnetic resonance imaging. It utilized a choke placed along the signal lines, with a gadolinium solution core. The choke's magnetic susceptibility was modeled, for a given geometric design, at increasing chelate concentration levels, and measured using a vibrating sample magnetometer. Radio frequency noise suppression versus frequency was quantified with network-analyzer measurements and tested using cabling placed in the magnetic resonance imaging scanner. Temperature-elevation and image-quality reduction due to the device were measured using American Society for Testing and Materials phantoms. Prototype chokes with gadolinium solution cores exhibited increasing magnetic susceptibility, and insertion loss (S21) also showed higher attenuation as gadolinium concentration increased. Image artifacts extending <4 mm from the choke were observed during magnetic resonance imaging, which agreed well with the predicted ∼3 mm artifact from the electrochemical machining simulation. An accompanying temperature increase of <1 °C was observed in the magnetic resonance imaging phantom trial. An effective paramagnetic choke for radio frequency suppression during magnetic resonance imaging was developed and its performance demonstrated.

[Functional connectivity of temporal parietal junction in online game addicts:a resting-state functional magnetic resonance imaging study].

PubMed

Yuan, Ji; Qian, Ruobing; Lin, Bin; Fu, Xianming; Wei, Xiangpin; Weng, Chuanbo; Niu, Chaoshi; Wang, Yehan

2014-02-11

To explore the functions of temporal parietal junction (TPJ) as parts of attention networks in the pathogenesis of online game addiction using resting-state functional magnetic resonance imaging (fMRI). A total of 17 online game addicts (OGA) were recruited as OGA group and 17 healthy controls during the same period were recruited as CON group. The neuropsychological tests were performed for all of them to compare the inter-group differences in the results of Internet Addiction Test (IAT) and attention functions. All fMRI data were preprocessed after resting-state fMRI scanning. Then left and right TPJ were selected as regions of interest (ROIs) to calculate the linear correlation between TPJ and entire brain to compare the inter-group differences. Obvious differences existed between OGA group (71 ± 5 scores) and CON group (19 ± 7 scores) in the IAT results and attention function (P < 0.05). Compared with the controls, right TPJ in online game addicts showed decreased functional connectivity with bilateral ventromedial prefrontal cortex (VMPFC), bilateral hippocampal gyrus and bilateral amygdaloid nucleus, but increased functional connectivity with right cuneus.However, left TPJ demonstrated decreased functional connectivity with bilateral superior frontal gyrus and bilateral middle frontal gyrus, but increased functional connectivity with bilateral cuneus (P < 0.05). Altered functional connectivity of TPJ reflected its dysfunction in online game addicts.It suggests that TPJ is an important component of attention networks participating in the generation of online game addiction.

Brain Lesions

MedlinePlus

... seen on a brain-imaging test, such as magnetic resonance imaging (MRI) or computerized tomography (CT). On ... A cohort study. PLOS One. 2013;8:e71467. Magnetic resonance imaging (MRI). National Multiple Sclerosis Society. http:// ...

Neuro magnetic resonance spectroscopy using wavelet decomposition and statistical testing identifies biochemical changes in people with spinal cord injury and pain.

PubMed

Stanwell, Peter; Siddall, Philip; Keshava, Nirmal; Cocuzzo, Daniel; Ramadan, Saadallah; Lin, Alexander; Herbert, David; Craig, Ashley; Tran, Yvonne; Middleton, James; Gautam, Shiva; Cousins, Michael; Mountford, Carolyn

2010-11-01

Spinal cord injury (SCI) can be accompanied by chronic pain, the mechanisms for which are poorly understood. Here we report that magnetic resonance spectroscopy measurements from the brain, collected at 3T, and processed using wavelet-based feature extraction and classification algorithms, can identify biochemical changes that distinguish control subjects from subjects with SCI as well as subdividing the SCI group into those with and without chronic pain. The results from control subjects (n=10) were compared to those with SCI (n=10). The SCI cohort was made up of subjects with chronic neuropathic pain (n=5) and those without chronic pain (n=5). The wavelet-based decomposition of frequency domain MRS signals employs statistical significance testing to identify features best suited to discriminate different classes. Moreover, the features benefit from careful attention to the post-processing of the spectroscopy data prior to the comparison of the three cohorts. The spectroscopy data, from the thalamus, best distinguished control subjects without SCI from those with SCI with a sensitivity and specificity of 0.9 (Percentage of Correct Classification). The spectroscopy data obtained from the prefrontal cortex and anterior cingulate cortex both distinguished between SCI subjects with chronic neuropathic pain and those without pain with a sensitivity and specificity of 1.0. In this study, where two underlying mechanisms co-exist (i.e. SCI and pain), the thalamic changes appear to be linked more strongly to SCI, while the anterior cingulate cortex and prefrontal cortex changes appear to be specifically linked to the presence of pain. Copyright 2010 Elsevier Inc. All rights reserved.

Development of III-Nitride Based THz Inter-Subband Lasers

DTIC Science & Technology

2009-09-30

tested both resonant tunneling diodes and quantum well infrared photodetectors in order to investigate quantum transport in III-Nitrides. Based on the...and tested both resonant tunneling diodes and quantum well infrared photodetectors in order to investigate quantum transport in III- Nitrides. Based...strain on bandstructure and piezo-as well as spontaneous- electric fields. Interband photoluminescence and intersubband absorption measurements were

Study to eliminate ground resonance using active controls

NASA Technical Reports Server (NTRS)

Straub, F. K.

1984-01-01

The effectiveness of active control blade feathering in increasing rotor body damping and the possibility to eliminate ground resonance instabilities were investigated. An analytical model representing rotor flapping and lead-lag degrees of freedom and body pitch, roll, longitudinal and lateral motion is developed. Active control blade feathering is implemented as state variable feedback through a conventional swashplate. The influence of various feedback states, feedback gain, and weighting between the cyclic controls is studied through stability and response analyses. It is shown that blade cyclic inplane motion, roll rate and roll acceleration feedback can add considerable damping to the system and eliminate ground resonance instabilities, which the feedback phase is also a powerful parameter, if chosen properly, it maximizes augmentation of the inherent regressing lag mode damping. It is shown that rotor configuration parameters, like blade root hinge offset, flapping stiffness, and precone considerably influence the control effectiveness. It is found that active control is particularly powerful for hingeless and bearingless rotor systems.

A Multi-Mode Blade Damping Control using Shunted Piezoelectric Transducers with Active Feedback Structure

NASA Technical Reports Server (NTRS)

Choi, Benjamin; Morrison, Carlos; Min, James

2009-01-01

The Structural Dynamics and. Mechanics branch (RXS) is developing smart adaptive structures to improve fan blade damping at resonances using piezoelectric (PE) transducers. In this presentation, only one shunted PE transducer was used to demonstrate active control of multi-mode blade resonance damping on a titanium alloy (Ti-6A1-4V) flat plate model, regardless of bending, torsion, and 2-stripe modes. This work would have a significant impact on the conventional passive shunt damping world because the standard feedback control design tools can now be used to design and implement electric shunt for vibration control. In other words, the passive shunt circuit components using massive inductors and. resistors for multi-mode resonance control can be replaced with digital codes. Furthermore, this active approach with multi patches can simultaneously control several modes in the engine operating range. Dr. Benjamin Choi presented the analytical and experimental results from this work at the Propulsion-Safety and. Affordable Readiness (P-SAR) Conference in March, 2009.

Control of Love waves by resonant metasurfaces.

PubMed

Palermo, Antonio; Marzani, Alessandro

2018-05-08

Metasurfaces of mechanical resonators have been successfully used to control in-plane polarized surface waves for filtering, waveguiding and lensing applications across different length scales. In this work, we extend the concept of metasurfaces to anti-plane surface waves existing in semi-infinite layered media, generally known as Love waves. By means of an effective medium approach, we derive an original closed-form dispersion relation for the metasurface. This relation reveals the possibility to control the Love waves dispersive properties by varying the resonators mechanical parameters. We exploit this capability to manipulate the metasurface refractive index and design two gradient index (GRIN) metalenses, i.e. a Luneburg lens and a Maxwell lens. We confirm the performance of the designed lenses using full 3D finite element simulations. Our work demonstrates the possibility of realizing wave control devices for anti-plane waves.

New Methods for Rotation Sensing by Using a Two-Coupler Fiber-Optic Ring Resonator

NASA Astrophysics Data System (ADS)

Seraji, Faramarz E.

1993-04-01

This paper presents a theoretical analysis of new methods for rotation sensing by using a two-coupler type fiber-optic ring resonator. It is shown that in the proposed methods a resonance spike can be generated whose amplitude gives a direct measure of the rotation rates. The approaches are simple and have a major advantage of not using a closed-loop to control the operating points for resonance.

Exact Tuning of High-Q Optical Microresonators by Use of UV

NASA Technical Reports Server (NTRS)

Savchankov, Anaotliy; Maleki, Lute; Iltchenko, Vladimir; Handley, Timothy

2006-01-01

In one of several alternative approaches to the design and fabrication of a "whispering-gallery" optical microresonator of high resonance quality (high Q), the index of refraction of the resonator material and, hence, the resonance frequencies. In this approach, a microresonator structure is prepared by forming it from an ultraviolet-sensitive material. Then the structure is subjected to controlled exposure to UV light while its resonance frequencies are monitored.

Feedback control of acoustic musical instruments: collocated control using physical analogs.

PubMed

Berdahl, Edgar; Smith, Julius O; Niemeyer, Günter

2012-01-01

Traditionally, the average professional musician has owned numerous acoustic musical instruments, many of them having distinctive acoustic qualities. However, a modern musician could prefer to have a single musical instrument whose acoustics are programmable by feedback control, where acoustic variables are estimated from sensor measurements in real time and then fed back in order to influence the controlled variables. In this paper, theory is presented that describes stable feedback control of an acoustic musical instrument. The presentation should be accessible to members of the musical acoustics community who may have limited or no experience with feedback control. First, the only control strategy guaranteed to be stable subject to any musical instrument mobility is described: the sensors and actuators must be collocated, and the controller must emulate a physical analog system. Next, the most fundamental feedback controllers and the corresponding physical analog systems are presented. The effects that these controllers have on acoustic musical instruments are described. Finally, practical design challenges are discussed. A proof explains why changing the resonance frequency of a musical resonance requires much more control power than changing the decay time of the resonance. © 2012 Acoustical Society of America.

The diagnostic accuracy of 1.5T magnetic resonance imaging for detecting root avulsions in traumatic adult brachial plexus injuries.

PubMed

Wade, Ryckie G; Itte, Vinay; Rankine, James J; Ridgway, John P; Bourke, Grainne

2018-03-01

Identification of root avulsions is of critical importance in traumatic brachial plexus injuries because it alters the reconstruction and prognosis. Pre-operative magnetic resonance imaging is gaining popularity, but there is limited and conflicting data on its diagnostic accuracy for root avulsion. This cohort study describes consecutive patients requiring brachial plexus exploration following trauma between 2008 and 2016. The index test was magnetic resonance imaging at 1.5 Tesla and the reference test was operative exploration of the supraclavicular plexus. Complete data from 29 males was available. The diagnostic accuracy of magnetic resonance imaging for root avulsion(s) of C5-T1 was 79%. The diagnostic accuracy of a pseudomeningocoele as a surrogate marker of root avulsion(s) of C5-T1 was 68%. We conclude that pseudomeningocoles were not a reliable sign of root avulsion and magnetic resonance imaging has modest diagnostic accuracy for root avulsions in the context of adult traumatic brachial plexus injuries. III.

Mechanical vibration testing of a tibia in vivo and finite element analysis of the shank resonant properties

NASA Astrophysics Data System (ADS)

Maslov, Leonid B.

2003-10-01

Recent clinical studies clearly indicate that the resonant frequencies can be used to assess the healing state of a fractured long bone. Although these studies clearly show a certain relation between the resonant frequencies and the stiffness of the bone, the nature of this relation has not yet studied very well. The attempt of considering the locomotion system of a human shank in complex is firstly presented in this paper. The finite element model of the soft and hard tissues composed of the human shank is developed and the vibration numerical analysis is performed. The values of the resonant frequencies for the isolated tibia and for the complex biomechanical system formed by tibia, fibula, achilles tendon and principal shank muscles are obtained during finite element analysis. The obtained result can be used as theoretical fundament to developing low-frequency resonant methods for testing and diagnostics of the physiological conditions of soft and hard tissue during medical treatment and rehabilitation time period after surgery operation.

Micromechanical Signal Processors

NASA Astrophysics Data System (ADS)

Nguyen, Clark Tu-Cuong

Completely monolithic high-Q micromechanical signal processors constructed of polycrystalline silicon and integrated with CMOS electronics are described. The signal processors implemented include an oscillator, a bandpass filter, and a mixer + filter--all of which are components commonly required for up- and down-conversion in communication transmitters and receivers, and all of which take full advantage of the high Q of micromechanical resonators. Each signal processor is designed, fabricated, then studied with particular attention to the performance consequences associated with miniaturization of the high-Q element. The fabrication technology which realizes these components merges planar integrated circuit CMOS technologies with those of polysilicon surface micromachining. The technologies are merged in a modular fashion, where the CMOS is processed in the first module, the microstructures in a following separate module, and at no point in the process sequence are steps from each module intermixed. Although the advantages of such modularity include flexibility in accommodating new module technologies, the developed process constrained the CMOS metallization to a high temperature refractory metal (tungsten metallization with TiSi _2 contact barriers) and constrained the micromachining process to long-term temperatures below 835^circC. Rapid-thermal annealing (RTA) was used to relieve residual stress in the mechanical structures. To reduce the complexity involved with developing this merged process, capacitively transduced resonators are utilized. High-Q single resonator and spring-coupled micromechanical resonator filters are also investigated, with particular attention to noise performance, bandwidth control, and termination design. The noise in micromechanical filters is found to be fairly high due to poor electromechanical coupling on the micro-scale with present-day technologies. Solutions to this high series resistance problem are suggested, including smaller electrode-to-resonator gaps to increase the coupling capacitance. Active Q-control techniques are demonstrated which control the bandwidth of micromechanical filters and simulate filter terminations with little passband distortion. Noise analysis shows that these active techniques are relatively quiet when compared with other resistive techniques. Modulation techniques are investigated whereby a single resonator or a filter constructed from several such resonators can provide both a mixing and a filtering function, or a filtering and amplitude modulation function. These techniques center around the placement of a carrier signal on the micromechanical resonator. Finally, micro oven stabilization is investigated in an attempt to null the temperature coefficient of a polysilicon micromechanical resonator. Here, surface micromachining procedures are utilized to fabricate a polysilicon resonator on a microplatform--two levels of suspension--equipped with heater and temperature sensing resistors, which are then imbedded in a feedback loop to control the platform (and resonator) temperature. (Abstract shortened by UMI.).

Manganese-enhanced magnetic resonance imaging detects mossy fiber sprouting in the pilocarpine model of epilepsy

PubMed Central

Malheiros, Jackeline M.; Polli, Roberson S.; Paiva, Fernando F.; Longo, Beatriz M.; Mello, Luiz E.; Silva, Afonso C.; Tannús, Alberto; Covolan, Luciene

2012-01-01

Summary Purpose Mossy fiber sprouting (MFS) is a frequent finding following status epilepticus (SE). The present study aimed to test the feasibility of using manganese-enhanced magnetic resonance imaging (MEMRI) to detect MFS in the chronic phase of the well-established pilocarpine (Pilo) rat model of temporal lobe epilepsy (TLE). Methods To modulate MFS, cycloheximide (CHX), a protein synthesis inhibitor, was co-administered with Pilo in a sub-group of animals. In vivo MEMRI was performed 3 months after induction of SE and compared to the neo-Timm histological labeling of zinc mossy fiber terminals in the dentate gyrus (DG). Key findings Chronically epileptic rats displaying MFS as detected by neo-Timm histology had a hyperintense MEMRI signal in the DG, while chronically epileptic animals that did not display MFS had minimal MEMRI signal enhancement compared to non-epileptic control animals. A strong correlation (r = 0.81, P<0.001) was found between MEMRI signal enhancement and MFS. Significance This study shows that MEMRI is an attractive non-invasive method to detect mossy fiber sprouting in vivo and can be used as an evaluation tool in testing therapeutic approaches to manage chronic epilepsy. PMID:22642664

Hybrid Active/Passive Jet Engine Noise Suppression System

NASA Technical Reports Server (NTRS)

Parente, C. A.; Arcas, N.; Walker, B. E.; Hersh, A. S.; Rice, E. J.

1999-01-01

A novel adaptive segmented liner concept has been developed that employs active control elements to modify the in-duct sound field to enhance the tone-suppressing performance of passive liner elements. This could potentially allow engine designs that inherently produce more tone noise but less broadband noise, or could allow passive liner designs to more optimally address high frequency broadband noise. A proof-of-concept validation program was undertaken, consisting of the development of an adaptive segmented liner that would maximize attenuation of two radial modes in a circular or annular duct. The liner consisted of a leading active segment with dual annuli of axially spaced active Helmholtz resonators, followed by an optimized passive liner and then an array of sensing microphones. Three successively complex versions of the adaptive liner were constructed and their performances tested relative to the performance of optimized uniform passive and segmented passive liners. The salient results of the tests were: The adaptive segmented liner performed well in a high flow speed model fan inlet environment, was successfully scaled to a high sound frequency and successfully attenuated three radial modes using sensor and active resonator arrays that were designed for a two mode, lower frequency environment.

Nuclear magnetic resonance imaging of water content in the subsurface

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Hendricks; T. Yao; A. Kearns

1999-01-21

Previous theoretical and experimental studies indicated that surface nuclear magnetic resonance (NMR) has the potential to provide cost-effective water content measurements in the subsurface and is a technology ripe for exploitation in practice. The objectives of this investigation are (a) to test the technique under a wide range of hydrogeological conditions and (b) to generalize existing NMR theories in order to correctly model NMR response from conductive ground and to assess properties of the inverse problem. Twenty-four sites with different hydrogeologic settings were selected in New Mexico and Colorado for testing. The greatest limitation of surface NMR technology appears tomore » be the lack of understanding in which manner the NMR signal is influenced by soil-water factors such as pore size distribution, surface-to-volume ratio, paramagnetic ions dissolved in the ground water, and the presence of ferromagnetic minerals. Although the theoretical basis is found to be sound, several advances need to be made to make surface NMR a viable technology for hydrological investigations. There is a research need to investigate, under controlled laboratory conditions, how the complex factors of soil-water systems affect NMR relaxation times.« less

Coherent signal amplification in bistable nanomechanical oscillators by stochastic resonance

NASA Astrophysics Data System (ADS)

Badzey, Robert L.; Mohanty, Pritiraj

2005-10-01

Stochastic resonance is a counterintuitive concept: the addition of noise to a noisy system induces coherent amplification of its response. First suggested as a mechanism for the cyclic recurrence of ice ages, stochastic resonance has been seen in a wide variety of macroscopic physical systems: bistable ring lasers, superconducting quantum interference devices (SQUIDs), magnetoelastic ribbons and neurophysiological systems such as the receptors in crickets and crayfish. Although fundamentally important as a mechanism of coherent signal amplification, stochastic resonance has yet to be observed in nanoscale systems. Here we report the observation of stochastic resonance in bistable nanomechanical silicon oscillators. Our nanomechanical systems consist of beams that are clamped at each end and driven into transverse oscillation with the use of a radiofrequency source. Modulation of the source induces controllable switching of the beams between two stable, distinct states. We observe that the addition of white noise causes a marked amplification of the signal strength. Stochastic resonance in nanomechanical systems could have a function in the realization of controllable high-speed nanomechanical memory cells, and paves the way for exploring macroscopic quantum coherence and tunnelling.

Graphene-induced modulation effects on magnetic plasmon in multilayer metal-dielectric-metal metamaterial

NASA Astrophysics Data System (ADS)

Li, Daimin; Wang, Wei; Zhang, Hong; Zhu, Yuhang; Zhang, Song; Zhang, Zhiyi; Zhang, Xinpeng; Yi, Juemin; Wei, Wei

2018-03-01

Motivated by the increasing interest in active control of the optical response in magnetic metamaterials, we theoretically demonstrate that monolayer graphene, even only a single atom thick, can provide an efficient modulation on the magnetic plasmon (MP) resonance, including over 10 meV resonance shift and over 25% modulation of resonance absorption intensity. We show that the resonance shift is distinctly different from the graphene-induced change in electrically excited surface plasmon resonances in plasmonic systems. Our analysis based on the equivalent nanocircuit method reveals that the MP resonance shift is governed by both the real and imaginary parts of graphene permittivity. Importantly, we find that an additional dissipation channel relevant to the graphene-induced resistance governs the MP absorption and that even the dissipation channel of interband transition is blocked. The interplay between both channels results in a pronounced modification of MP absorption intensities. The findings will offer a promising way to realize the dynamic control of the magnetic response, which holds great potential applications in graphene-based active metamaterials.

Magnetic resonance imaging and magnetic resonance spectroscopy for detection of early Alzheimer's disease.

PubMed

Westman, Eric; Wahlund, Lars-Olof; Foy, Catherine; Poppe, Michaela; Cooper, Allison; Murphy, Declan; Spenger, Christian; Lovestone, Simon; Simmons, Andrew

2011-01-01

Alzheimer's disease is the most common form of neurodegenerative disorder and early detection is of great importance if new therapies are to be effectively administered. We have investigated whether the discrimination between early Alzheimer's disease (AD) and elderly healthy control subjects can be improved by adding magnetic resonance spectroscopy (MRS) measures to magnetic resonance imaging (MRI) measures. In this study 30 AD patients and 36 control subjects were included. High resolution T1-weighted axial magnetic resonance images were obtained from each subject. Automated regional volume segmentation and cortical thickness measures were determined for the images. 1H MRS was acquired from the hippocampus and LCModel was used for metabolic quantification. Altogether, this yielded 58 different volumetric, cortical thickness and metabolite ratio variables which were used for multivariate analysis to distinguish between subjects with AD and Healthy controls. Combining MRI and MRS measures resulted in a sensitivity of 97% and a specificity of 94% compared to using MRI or MRS measures alone (sensitivity: 87%, 76%, specificity: 86%, 83% respectively). Adding the MRS measures to the MRI measures more than doubled the positive likelihood ratio from 6 to 17. Adding MRS measures to a multivariate analysis of MRI measures resulted in significantly better classification than using MRI measures alone. The method shows strong potential for discriminating between Alzheimer's disease and controls.

Phase control of the transient resonance of the automatic ball balancer

NASA Astrophysics Data System (ADS)

Michalczyk, Jerzy; Pakuła, Sebastian

2016-05-01

Hazards related to undesired increases of vibration amplitudes in transient resonance of vibroinsulated rotor systems with automatic ball balancer (ABB) are discussed in the paper. The application of the phase control method with taking into account the limited drive power is proposed for these amplitudes reduction. The high efficiency of this approach is indicated.

Implementation of quantum logic gates via Stark-tuned Förster resonance in Rydberg atoms

NASA Astrophysics Data System (ADS)

Huang, Xi-Rong; Hu, Chang-Sheng; Shen, Li-Tuo; Yang, Zhen-Biao; Wu, Huai-Zhi

2018-02-01

We present a scheme for implementation of controlled-Z and controlled-NOT gates via rapid adiabatic passage and Stark-tuned Förster resonance. By sweeping the Förster resonance once without passing through it and adiabatically tuning the angle-dependent Rydberg-Rydberg interaction of the dipolar nature, the system can be effectively described by a two-level system with the adiabatic theorem. The single adiabatic passage leads to a gate fidelity as high as 0.999 and a greatly reduced gate operation time. We investigate the scheme by considering an actual atomic level configuration with rubidium atoms, where the fidelity of the controlled-Z gate is still higher than 0.99 under the influence of the Zeeman effect.

Quasi-monolithic tunable optical resonator

NASA Technical Reports Server (NTRS)

Arbore, Mark (Inventor); Tapos, Francisc (Inventor)

2003-01-01

An optical resonator has a piezoelectric element attached to a quasi-monolithic structure. The quasi-monolithic structure defines an optical path. Mirrors attached to the structure deflect light along the optical path. The piezoelectric element controllably strains the quasi-monolithic structure to change a length of the optical path by about 1 micron. A first feedback loop coupled to the piezoelectric element provides fine control over the cavity length. The resonator may include a thermally actuated spacer attached to the cavity and a mirror attached to the spacer. The thermally actuated spacer adjusts the cavity length by up to about 20 microns. A second feedback loop coupled to the sensor and heater provides a coarse control over the cavity length. An alternative embodiment provides a quasi-monolithic optical parametric oscillator (OPO). This embodiment includes a non-linear optical element within the resonator cavity along the optical path. Such an OPO configuration is broadly tunable and capable of mode-hop free operation for periods of 24 hours or more.

Dynamically controlled electromagnetically induced transparency in terahertz graphene metamaterial for modulation and slow light applications

NASA Astrophysics Data System (ADS)

He, Xunjun; Yao, Yuan; Yang, Xingyu; Lu, Guangjun; Yang, Wenlong; Yang, Yuqiang; Wu, Fengmin; Yu, Zhigang; Jiang, Jiuxing

2018-03-01

By patterning two graphene resonators on a SiO2/Si substrate, a dynamically controlled electromagnetically induced transparency (EIT) in the terahertz graphene metamaterial was numerically studied through tuning the structural parameter and Fermi energy of graphene. The calculated surface current distributions demonstrate that the distinct EIT window in the graphene metamaterial results from the near-field coupling of two graphene resonators. Moreover, the EIT window can be actively controlled by tuning Fermi energy combined states of two resonators. When the Fermi energy combined state of two resonators changes from (0.21 and 0.16 eV) to (0.4 and 0.11 eV), the amplitude modulation depth of the EIT peak is 97.8% at 0.45 THz, and the corresponding enhanced factor of group delay with 6 times is obtained. This study offers an alternative tuning method to existing optical, thermal, and relative distance tuning, delivering a promising potential for designing active and miniaturized THz devices.

System and component design and test of a 10 hp, 18,000 rpm AC dynamometer utilizing a high frequency AC voltage link, part 1

NASA Technical Reports Server (NTRS)

Lipo, Thomas A.; Alan, Irfan

1991-01-01

Hard and soft switching test results conducted with one of the samples of first generation MOS-controlled thyristor (MCTs) and similar test results with several different samples of second generation MCT's are reported. A simple chopper circuit is used to investigate the basic switching characteristics of MCT under hard switching and various types of resonant circuits are used to determine soft switching characteristics of MCT under both zero voltage and zero current switching. Next, operation principles of a pulse density modulated converter (PDMC) for three phase (3F) to 3F two-step power conversion via parallel resonant high frequency (HF) AC link are reviewed. The details for the selection of power switches and other power components required for the construction of the power circuit for the second generation 3F to 3F converter system are discussed. The problems encountered in the first generation system are considered. Design and performance of the first generation 3F to 3F power converter system and field oriented induction moter drive based upon a 3 kVA, 20 kHz parallel resonant HF AC link are described. Low harmonic current at the input and output, unity power factor operation of input, and bidirectional flow capability of the system are shown via both computer and experimental results. The work completed on the construction and testing of the second generation converter and field oriented induction motor drive based upon specifications for a 10 hp squirrel cage dynamometer and a 20 kHz parallel resonant HF AC link is discussed. The induction machine is designed to deliver 10 hp or 7.46 kW when operated as an AC-dynamo with power fed back to the source through the converter. Results presented reveal that the proposed power level requires additional energy storage elements to overcome difficulties with a peak link voltage variation problem that limits reaching to the desired power level. The power level test of the second generation converter after the addition of extra energy storage elements to the HF link are described. The importance of the source voltage level to achieve a better current regulation for the source side PDMC is also briefly discussed. The power levels achieved in the motoring mode of operation show that the proposed power levels achieved in the generating mode of operation can also be easily achieved provided that no mechanical speed limitation were present to drive the induction machine at the proposed power level.

Acromion Index in Korean Population and Its Relationship with Rotator Cuff Tears.

PubMed

Kum, Dong Ho; Kim, Jun Ho; Park, Keun Min; Lee, Eun Su; Park, Yong Bok; Yoo, Jae Chul

2017-06-01

Among the many causes of rotator cuff tears, scapular morphology is associated with the accelerating degenerative process of the rotator cuff. Acromion index (AI) was previously introduced and compared in two populations. We enrolled 100 Korean patients diagnosed with full-thickness rotator cuff tears by magnetic resonance imaging and intraoperative arthroscopic findings between January and December 2013. Another 100 Korean patients with an intact rotator cuff tendon identified on magnetic resonance imaging and other shoulder diseases, such as frozen shoulder and instability, were enrolled as controls. We retrospectively compared these 100 rotator cuff tear patients (mean age, 63 years) and 100 controls (mean age, 51 years) in this study. Two independent orthopedic surgeons assessed the AI on radiographs. We performed an interobserver reliability test of the AI assessment, and then compared the AI between two groups. The measurement of the AI showed excellent reliability (intraclass correlation coefficient, 0.82). The mean AI in the rotator cuff tear group was 0.68 and it was significantly different between groups ( p <0.001, 95% confidence interval). The AI was not related to tear size. Our study showed that the AI was an effective predictive factor for rotator cuff tears in a Korean population.

Fatigue Testing of Wing Beam by the Resonance Method

NASA Technical Reports Server (NTRS)

Bleakney, William M

1938-01-01

Preliminary fatigue tests on two aluminum-alloy wing-beam specimens subjected to reversed axial loading are described. The motion used consists in incorporating one or two reciprocating motors in a resonance system of which the specimen is the spring element. A description is given of the reciprocating motors, and of the method of assembling and adjusting the vibrating system. The results indicate that the method is well adapted to fatigue tests of not only uniform wing beams but also wing beams with asymmetrical local reinforcements.

Study on Dynamic Alignment Technology of COIL Resonator

NASA Astrophysics Data System (ADS)

Xiong, M. D.; Zou, X. J.; Guo, J. H.; Jia, S. N.; Zhang2, Z. B.

2006-10-01

The performance of great power chemical oxygen-iodine laser (COIL) beam is decided mostly by resonator mirror maladjustment and environment vibration. To improve the performance of light beam, an auto-alignment device is used in COIL resonator, the device can keep COIL resonator collimating by adjusting the optical components of resonator. So the coupling model of COIL resonator is present. The multivariable self study fuzzy uncoupling arithmetic and six-dimensional micro drive technology are used to design a six-input-three-output uncoupling controller, resulting in the realization of the high precision dynamic alignment. The experiments indicate that the collimating range of this system is 8 mrad, precision is 5 urad and frequency response is 20Hz, which meet the demand of resonator alignment system.

Lossless crossing of a resonance stopband during tune modulation by synchrotron oscillations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, G. M.; Shaftan, T.; Smaluk, V.

Modern high performance circular accelerators require sophisticated corrections of nonlinear lattices. The beam betatron tune footprint may cross many resonances, reducing dynamic aperture and causing particle loss. But, if particles cross a resonance reasonably fast, the beam deterioration may be minimized. This paper describes the experiments with the beam passing through a half-integer resonance stopband via tune modulation by exciting synchrotron oscillations. This is the first time that beam dynamics have been kept under precise control while the beam crosses a half-integer resonance. These results convincingly demonstrate that particles can cross the half-integer resonance without being lost if the passagemore » is reasonably fast and the resonance stopband is sufficiently narrow.« less

Lossless crossing of a resonance stopband during tune modulation by synchrotron oscillations

DOE PAGES

Wang, G. M.; Shaftan, T.; Smaluk, V.; ...

2017-09-14

Modern high performance circular accelerators require sophisticated corrections of nonlinear lattices. The beam betatron tune footprint may cross many resonances, reducing dynamic aperture and causing particle loss. But, if particles cross a resonance reasonably fast, the beam deterioration may be minimized. This paper describes the experiments with the beam passing through a half-integer resonance stopband via tune modulation by exciting synchrotron oscillations. This is the first time that beam dynamics have been kept under precise control while the beam crosses a half-integer resonance. These results convincingly demonstrate that particles can cross the half-integer resonance without being lost if the passagemore » is reasonably fast and the resonance stopband is sufficiently narrow.« less

Adaptive Augmenting Control Flight Characterization Experiment on an F/A-18

NASA Technical Reports Server (NTRS)

VanZwieten, Tannen S.; Orr, Jeb S.; Wall, John H.; Gilligan, Eric T.

2014-01-01

This paper summarizes the Adaptive Augmenting Control (AAC) flight characterization experiments performed using an F/A-18 (TN 853). AAC was designed and developed specifically for launch vehicles, and is currently part of the baseline autopilot design for NASA's Space Launch System (SLS). The scope covered here includes a brief overview of the algorithm (covered in more detail elsewhere), motivation and benefits of flight testing, top-level SLS flight test objectives, applicability of the F/A-18 as a platform for testing a launch vehicle control design, test cases designed to fully vet the AAC algorithm, flight test results, and conclusions regarding the functionality of AAC. The AAC algorithm developed at Marshall Space Flight Center is a forward loop gain multiplicative adaptive algorithm that modifies the total attitude control system gain in response to sensed model errors or undesirable parasitic mode resonances. The AAC algorithm provides the capability to improve or decrease performance by balancing attitude tracking with the mitigation of parasitic dynamics, such as control-structure interaction or servo-actuator limit cycles. In the case of the latter, if unmodeled or mismodeled parasitic dynamics are present that would otherwise result in a closed-loop instability or near instability, the adaptive controller decreases the total loop gain to reduce the interaction between these dynamics and the controller. This is in contrast to traditional adaptive control logic, which focuses on improving performance by increasing gain. The computationally simple AAC attitude control algorithm has stability properties that are reconcilable in the context of classical frequency-domain criteria (i.e., gain and phase margin). The algorithm assumes that the baseline attitude control design is well-tuned for a nominal trajectory and is designed to adapt only when necessary. Furthermore, the adaptation is attracted to the nominal design and adapts only on an as-needed basis (see Figure 1). The MSFC algorithm design was formulated during the Constellation Program and reached a high maturity level during SLS through simulation-based development and internal and external analytical review. The AAC algorithm design has three summary-level objectives: (1) "Do no harm;" return to baseline control design when not needed, (2) Increase performance; respond to error in ability of vehicle to track command, and (3) Regain stability; respond to undesirable control-structure interaction or other parasitic dynamics. AAC has been successfully implemented as part of the Space Launch System baseline design, including extensive testing in high-fidelity 6-DOF simulations the details of which are described in [1]. The Dryden Flight Research Center's F/A-18 Full-Scale Advanced Systems Testbed (FAST) platform is used to conduct an algorithm flight characterization experiment intended to fully vet the aforementioned design objectives. FAST was specifically designed with this type of test program in mind. The onboard flight control system has full-authority experiment control of ten aerodynamic effectors and two throttles. It has production and research sensor inputs and pilot engage/disengage and real-time configuration of up to eight different experiments on a single flight. It has failure detection and automatic reversion to fail-safe mode. The F/A-18 aircraft has an experiment envelope cleared for full-authority control and maneuvering and exhibits characteristics for robust recovery from unusual attitudes and configurations aided by the presence of a qualified test pilot. The F/A-18 aircraft has relatively high mass and inertia with exceptional performance; the F/A-18 also has a large thrust-to-weight ratio, owing to its military heritage. This enables the simulation of a portion of the ascent trajectory with a high degree of dynamic similarity to a launch vehicle, and the research flight control system can simulate unstable longitudinal dynamics. Parasitic dynamics such as slosh and bending modes, as well as atmospheric disturbances, are being produced by the airframe via modification of bending filters and the use of secondary control surfaces, including leading and trailing edge flaps, symmetric ailerons, and symmetric rudders. The platform also has the ability to inject signals in flight to simulate structural mode resonances or other challenging dynamics. This platform also offers more test maneuvers and longer maneuver times than a single rocket or missile test, which provides ample opportunity to fully and repeatedly exercise all aspects of the algorithm. Prior to testing on an F/A-18, AAC was the only component of the SLS autopilot design that had not been flight tested. The testing described in this paper raises the Technology Readiness Level (TRL) early in the SLS Program and is able to demonstrate its capabilities and robustness in a flight environment.

Optical notch filter with tunable bandwidth based on guided-mode resonant polarization-sensitive spectral feature.

PubMed

Qian, Linyong; Zhang, Dawei; Dai, Bo; Wang, Qi; Huang, Yuanshen; Zhuang, Songlin

2015-07-13

A novel bandwidth-tunable notch filter is proposed based on the guided-mode resonance effect. The notch is created due to the superposition spectra response of two guided-mode resonant filters. The compact, bandwidth tuning capability is realized by taking advantage the effect of spectra-to-polarization sensitivity in one-dimensional classical guided-mode resonance filter, and using a liquid crystal polarization rotator for precise and simple polarization control. The operation principle and the design of the device are presented, and we demonstrate it experimentally. The central wavelength is fixed at 766.4 nm with a relatively symmetric profile. The full width at half maximum bandwidth could be tuned from 8.6 nm to 18.2 nm by controlling the applied voltage in electrically-driving polarization rotator.

Circularly polarized microwaves for magnetic resonance study in the GHz range: Application to nitrogen-vacancy in diamonds

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mrózek, M., E-mail: mariusz.mrozek@uj.edu.pl; Rudnicki, D. S.; Gawlik, W.

2015-07-06

The ability to create time-dependent magnetic fields of controlled polarization is essential for many experiments with magnetic resonance. We describe a microstrip circuit that allows us to generate strong magnetic field at microwave frequencies with arbitrary adjusted polarization. The circuit performance is demonstrated by applying it to an optically detected magnetic resonance and Rabi nutation experiments in nitrogen-vacancy color centers in diamond. Thanks to high efficiency of the proposed microstrip circuit and degree of circular polarization of 85%; it is possible to address the specific spin states of a diamond sample using a low power microwave generator. The circuit maymore » be applied to a wide range of magnetic resonance experiments with a well-controlled polarization of microwaves.« less

A process to control light in a micro resonator through a coupling modulation by surface acoustic waves

NASA Astrophysics Data System (ADS)

Fan, Guofang; Li, Yuan; Hu, Chunguang; Lei, Lihua; Guo, Yanchuan

2016-08-01

A novel process to control light through the coupling modulation by surface acoustic wave (SAW) is presented in an optical micro resonator. An optical waveguide modulator of a racetrack resonator on silicon-on-insulator (SOI) technology is took as an example to explore the mechanism. A finite-difference time-domain (FDTD) is developed to simulate the acousto-optical (AO) modulator using the mechanism. An analytical method is presented to verify our proposal. The results show that the process can work well as an optical modulator by SAW.

Nanosecond-pulse-controlled higher-order sideband comb in a GaAs optomechanical disk resonator in the non-perturbative regime

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiong, Hao, E-mail: haoxiong1217@gmail.com; Si, Liu-Gang, E-mail: siliugang@gmail.com; Lü, Xin-You

2014-10-15

We propose an interesting scheme for tunable high-order sideband comb generation by utilizing ultrastrong optomechanical interaction in a GaAs optomechanical disk resonator beyond the perturbative approximation. We analyze the nonlinear nature of the optomechanical interaction, and give a full description of the non-perturbative effects. It is shown, within the non-perturbative regime, that high-order sideband comb with large intensities can be realized and controlled in a GaAs optomechanical disk resonator with experimentally achievable system parameters, and the non-perturbative regime leads to rich and nontrivial behavior.

Chiral symmetry constraints on resonant amplitudes

NASA Astrophysics Data System (ADS)

Bruns, Peter C.; Mai, Maxim

2018-03-01

We discuss the impact of chiral symmetry constraints on the quark-mass dependence of meson resonance pole positions, which are encoded in non-perturbative parametrizations of meson scattering amplitudes. Model-independent conditions on such parametrizations are derived, which are shown to guarantee the correct functional form of the leading quark-mass corrections to the resonance pole positions. Some model amplitudes for ππ scattering, widely used for the determination of ρ and σ resonance properties from results of lattice simulations, are tested explicitly with respect to these conditions.

33 CFR 159.103 - Vibration test.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., with liquid retention components, if any, filled with water to one-half of their volume, must be... the resonant frequency of the device (or at 55 cycles per second if there is no resonant frequency...

33 CFR 159.103 - Vibration test.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., with liquid retention components, if any, filled with water to one-half of their volume, must be... the resonant frequency of the device (or at 55 cycles per second if there is no resonant frequency...

33 CFR 159.103 - Vibration test.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., with liquid retention components, if any, filled with water to one-half of their volume, must be... the resonant frequency of the device (or at 55 cycles per second if there is no resonant frequency...

33 CFR 159.103 - Vibration test.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., with liquid retention components, if any, filled with water to one-half of their volume, must be... the resonant frequency of the device (or at 55 cycles per second if there is no resonant frequency...

Test Methodology Development for Experimental Structural Assessment of ASC Planar Spring Material for Long-Term Durability

NASA Technical Reports Server (NTRS)

Yun, Gunjin; Abdullah, A. B. M.; Binienda, Wieslaw; Krause, David L.; Kalluri, Sreeramesh

2014-01-01

A vibration-based testing methodology has been developed that will assess fatigue behavior of the metallic material of construction for the Advanced Stirling Convertor displacer (planar) spring component. To minimize the testing duration, the test setup is designed for base-excitation of a multiplespecimen arrangement, driven in a high-frequency resonant mode; this allows completion of fatigue testing in an accelerated period. A high performance electro-dynamic exciter (shaker) is used to generate harmonic oscillation of cantilever beam specimens, which are clasped on the shaker armature with specially-designed clamp fixtures. The shaker operates in closed-loop control with dynamic specimen response feedback provided by a scanning laser vibrometer. A test coordinator function synchronizes the shaker controller and the laser vibrometer to complete the closed-loop scheme. The test coordinator also monitors structural health of the test specimens throughout the test period, recognizing any change in specimen dynamic behavior. As this may be due to fatigue crack initiation, the test coordinator terminates test progression and then acquires test data in an orderly manner. Design of the specimen and fixture geometry was completed by finite element analysis such that peak stress does not occur at the clamping fixture attachment points. Experimental stress evaluation was conducted to verify the specimen stress predictions. A successful application of the experimental methodology was demonstrated by validation tests with carbon steel specimens subjected to fully-reversed bending stress; high-cycle fatigue failures were induced in such specimens using higher-than-prototypical stresses

Development of Low $$\\beta $$ Single-Spoke Resonators for the Front End of the Proton Improvement Plan-II at Fermilab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Awida, Mohamed H.; Passarelli, Donato; Berrutti, Paolo

A total of ten jacketed single-spoke resonators type 1 (SSR1) have been fabricated for Fermilab' injection experiment (PIP2IT). PIP2IT is a test bed for Fermilab's future accelerator named proton improvement plan II that is currently under development. SSR1 cavities operate at 325 MHz to accelerate a proton beam at a relative (to speed of light) velocity (β = 0.22). In this study, we present Fermilab's experience in developing those spoke resonators starting from the design and analysis phase, to fabrication and extensive testing to qualify cavities for cryomodule assembly.

Fabrication and Testing of Microfluidic Optomechanical Oscillators

PubMed Central

Han, Kewen; Kim, Kyu Hyun; Kim, Junhwan; Lee, Wonsuk; Liu, Jing; Fan, Xudong; Carmon, Tal; Bahl, Gaurav

2014-01-01

Cavity optomechanics experiments that parametrically couple the phonon modes and photon modes have been investigated in various optical systems including microresonators. However, because of the increased acoustic radiative losses during direct liquid immersion of optomechanical devices, almost all published optomechanical experiments have been performed in solid phase. This paper discusses a recently introduced hollow microfluidic optomechanical resonator. Detailed methodology is provided to fabricate these ultra-high-Q microfluidic resonators, perform optomechanical testing, and measure radiation pressure-driven breathing mode and SBS-driven whispering gallery mode parametric vibrations. By confining liquids inside the capillary resonator, high mechanical- and optical- quality factors are simultaneously maintained. PMID:24962013

Development of Low $$\\beta $$ Single-Spoke Resonators for the Front End of the Proton Improvement Plan-II at Fermilab

DOE PAGES

Awida, Mohamed H.; Passarelli, Donato; Berrutti, Paolo; ...

2017-08-18

A total of ten jacketed single-spoke resonators type 1 (SSR1) have been fabricated for Fermilab' injection experiment (PIP2IT). PIP2IT is a test bed for Fermilab's future accelerator named proton improvement plan II that is currently under development. SSR1 cavities operate at 325 MHz to accelerate a proton beam at a relative (to speed of light) velocity (β = 0.22). In this study, we present Fermilab's experience in developing those spoke resonators starting from the design and analysis phase, to fabrication and extensive testing to qualify cavities for cryomodule assembly.

Resonant scattering of energetic electrons in the plasmasphere by monotonic whistler-mode waves artificially generated by ionospheric modification

NASA Astrophysics Data System (ADS)

Chang, S. S.; Ni, B. B.; Bortnik, J.; Zhou, C.; Zhao, Z. Y.; Li, J. X.; Gu, X. D.

2014-05-01

Modulated high-frequency (HF) heating of the ionosphere provides a feasible means of artificially generating extremely low-frequency (ELF)/very low-frequency (VLF) whistler waves, which can leak into the inner magnetosphere and contribute to resonant interactions with high-energy electrons in the plasmasphere. By ray tracing the magnetospheric propagation of ELF/VLF emissions artificially generated at low-invariant latitudes, we evaluate the relativistic electron resonant energies along the ray paths and show that propagating artificial ELF/VLF waves can resonate with electrons from ~ 100 keV to ~ 10 MeV. We further implement test particle simulations to investigate the effects of resonant scattering of energetic electrons due to triggered monotonic/single-frequency ELF/VLF waves. The results indicate that within the period of a resonance timescale, changes in electron pitch angle and kinetic energy are stochastic, and the overall effect is cumulative, that is, the changes averaged over all test electrons increase monotonically with time. The localized rates of wave-induced pitch-angle scattering and momentum diffusion in the plasmasphere are analyzed in detail for artificially generated ELF/VLF whistlers with an observable in situ amplitude of ~ 10 pT. While the local momentum diffusion of relativistic electrons is small, with a rate of < 10-7 s-1, the local pitch-angle scattering can be intense near the loss cone with a rate of ~ 10-4 s-1. Our investigation further supports the feasibility of artificial triggering of ELF/VLF whistler waves for removal of high-energy electrons at lower L shells within the plasmasphere. Moreover, our test particle simulation results show quantitatively good agreement with quasi-linear diffusion coefficients, confirming the applicability of both methods to evaluate the resonant diffusion effect of artificial generated ELF/VLF whistlers.

SS-HORSE method for studying resonances

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blokhintsev, L. D.; Mazur, A. I.; Mazur, I. A., E-mail: 008043@pnu.edu.ru

A new method for analyzing resonance states based on the Harmonic-Oscillator Representation of Scattering Equations (HORSE) formalism and analytic properties of partial-wave scattering amplitudes is proposed. The method is tested by applying it to the model problem of neutral-particle scattering and can be used to study resonance states on the basis of microscopic calculations performed within various versions of the shell model.

Scary symptoms? Functional magnetic resonance imaging evidence for symptom interpretation bias in pathological health anxiety.

PubMed

Yan, Zhimin; Witthöft, Michael; Bailer, Josef; Diener, Carsten; Mier, Daniela

2017-08-12

Patients with pathological health anxiety (PHA) tend to automatically interpret bodily sensations as sign of a severe illness. To elucidate the neural correlates of this cognitive bias, we applied an functional magnetic resonance imaging adaption of a body-symptom implicit association test with symptom words in patients with PHA (n = 32) in comparison to patients with depression (n = 29) and healthy participants (n = 35). On the behavioral level, patients with PHA did not significantly differ from the control groups. However, on the neural-level patients with PHA in comparison to the control groups showed hyperactivation independent of condition in bilateral amygdala, right parietal lobe, and left nucleus accumbens. Moreover, patients with PHA, again in comparison to the control groups, showed hyperactivation in bilateral posterior parietal cortex and left dorsolateral prefrontal cortex during incongruent (i.e., harmless) versus congruent (i.e., dangerous) categorizations of body symptoms. Thus, body-symptom cues seem to trigger hyperactivity in salience and emotion processing brain regions in PHA. In addition, hyperactivity in brain regions involved in cognitive control and conflict resolution during incongruent categorization emphasizes enhanced neural effort to cope with negative implicit associations to body-symptom-related information in PHA. These results suggest increased neural responding in key structures for the processing of both emotional and cognitive aspects of body-symptom information in PHA, reflecting potential neural correlates of a negative somatic symptom interpretation bias.

Activation of prefrontal cortex and anterior thalamus in alcoholic subjects on exposure to alcohol-specific cues.

PubMed

George, M S; Anton, R F; Bloomer, C; Teneback, C; Drobes, D J; Lorberbaum, J P; Nahas, Z; Vincent, D J

2001-04-01

Functional imaging studies have recently demonstrated that specific brain regions become active in cocaine addicts when they are exposed to cocaine stimuli. To test whether there are regional brain activity differences during alcohol cue exposure between alcoholic subjects and social drinkers, we designed a functional magnetic resonance imaging (fMRI) protocol involving alcohol-specific cues. Ten non-treatment-seeking adult alcoholic subjects (2 women) (mean [SD] age, 29.9 [9.9] years) as well as 10 healthy social drinking controls of similar age (2 women) (mean [SD] age, 29.4 [8.9] years) were recruited, screened, and scanned. In the 1.5-T magnetic resonance imaging scanner, subjects were serially rated for alcohol craving before and after a sip of alcohol, and after a 9-minute randomized presentation of pictures of alcoholic beverages, control nonalcoholic beverages, and 2 different visual control tasks. During picture presentation, changes in regional brain activity were measured with the blood oxygen level-dependent technique. Alcoholic subjects, compared with the social drinking subjects, reported higher overall craving ratings for alcohol. After a sip of alcohol, while viewing alcohol cues compared with viewing other beverage cues, only the alcoholic subjects had increased activity in the left dorsolateral prefrontal cortex and the anterior thalamus. The social drinkers exhibited specific activation only while viewing the control beverage pictures. When exposed to alcohol cues, alcoholic subjects have increased brain activity in the prefrontal cortex and anterior thalamus-brain regions associated with emotion regulation, attention, and appetitive behavior.

FREQUENCY CONTROL OF RF HEATING OF GASEOUS PLASMA

DOEpatents

Herold, E.W.

1962-09-01

This invention relates to the heating of gaseous plasma by radiofrequency ion-cyclotron resonance heating. The cyclotron resonance frequencies are varied and this invention provides means for automatically controlling the frequency of the radiofrequency to maximize the rate of heating. To this end, a servo-loop is provided to sense the direction of plasma heating with frequency and a control signal is derived to set the center frequency of the radiofrequency energy employed to heat the plasma. (AEC)

Active Vibration Reduction of Titanium Alloy Fan Blades (FAN1) Using Piezoelectric Materials

NASA Technical Reports Server (NTRS)

Choi, Benjamin; Kauffman, Jeffrey; Duffy, Kirsten; Provenza, Andrew; Morrison, Carlos

2010-01-01

The NASA Glenn Research Center is developing smart adaptive structures to improve fan blade damping at resonances using piezoelectric (PE) transducers. In this paper, a digital resonant control technique emulating passive shunt circuits is used to demonstrate vibration reduction of FAN1 Ti real fan blade at the several target modes. Single-mode control and multi-mode control using one piezoelectric material are demonstrated. Also a conceptual study of how to implement this digital control system into the rotating fan blade is discussed.

Integrated narrowband optical filter based on embedded subwavelength resonant grating structures

DOEpatents

Grann, Eric B.; Sitter, Jr., David N.

2000-01-01

A resonant grating structure in a waveguide and methods of tuning the performance of the grating structure are described. An apparatus includes a waveguide; and a subwavelength resonant grating structure embedded in the waveguide. The systems and methods provide advantages including narrowband filtering capabilities, minimal sideband reflections, spatial control, high packing density, and tunability.

Description of A 2.3 kW power transformer for space applications

NASA Technical Reports Server (NTRS)

Hansen, I.

1979-01-01

The paper describes the principal features and special testing of a high-frequency high-power low-specific-weight (0.57 kg/kW) 2.3-kW electronic power transformer developed for space applications. The transformer is operated in a series resonant inverter supplying beam power to a 30-cm mercury ion thruster. High efficiency (above 98.5%) is obtained through careful detailed design. A number of unique heat removal techniques are discussed which control the winding temperature using only the available conductive cooling.

[Post-partum posterior reversible encephalopathy syndrome].

PubMed

Aaen, Anne Albers; Jeppesen, Jørgen; Obaid, Hayder; Bülow, Hans Henrik

2015-11-23

Posterior reversible encephalopathy syndrome (PRES) is a complex clinical condition with vasogenic subcortical oedema caused by hypertension. Oedema is often seen on magnetic resonance imaging. The wide clinical spectrum ranges from headaches to vision loss and even death. Early diagnosis and treatment is important for the reversibility of the condition. In this case report we emphasize the importance of blood pressure control in a post-partum woman, who had a rather complicated pregnancy. The symptoms of PRES were not recognized immediately because of failure to use and acknowledge a blood pressure test.

Semiconductor technology program. Progress briefs

NASA Technical Reports Server (NTRS)

Bullis, W. M. (Editor)

1979-01-01

The current status of NBS work on measurement technology for semiconductor materials, process control, and devices is reported. Results of both in-house and contract research are covered. Highlighted activities include modeling of diffusion processes, analysis of model spreading resistance data, and studies of resonance ionization spectroscopy, resistivity-dopant density relationships in p-type silicon, deep level measurements, photoresist sensitometry, random fault measurements, power MOSFET thermal characteristics, power transistor switching characteristics, and gross leak testing. New and selected on-going projects are described. Compilations of recent publications and publications in press are included.