WE-E-18A-07: MAGIC: Multi-Acquisition Gain Image Correction for Mobile X-Ray Systems with Intrinsic Localization Crosshairs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Y; Sharp, G

2014-06-15

Purpose: Gain calibration for X-ray imaging systems with movable flat panel detectors (FPD) and intrinsic crosshairs is a challenge due to the geometry dependence of the heel effect and crosshair artifact. This study aims to develop a gain correction method for such systems by implementing the multi-acquisition gain image correction (MAGIC) technique. Methods: Raw flat-field images containing crosshair shadows and heel effect were acquired in 4 different FPD positions with fixed exposure parameters. The crosshair region was automatically detected and substituted with interpolated values from nearby exposed regions, generating a conventional single-image gain-map for each FPD position. Large kernel-based correctionmore » was applied to these images to correct the heel effect. A mask filter was used to invalidate the original cross-hair regions previously filled with the interpolated values. A final, seamless gain-map was created from the processed images by either the sequential filling (SF) or selective averaging (SA) techniques developed in this study. Quantitative evaluation was performed based on detective quantum efficiency improvement factor (DQEIF) for gain-corrected images using the conventional and proposed techniques. Results: Qualitatively, the MAGIC technique was found to be more effective in eliminating crosshair artifacts compared to the conventional single-image method. The mean DQEIF over the range of frequencies from 0.5 to 3.5 mm-1 were 1.09±0.06, 2.46±0.32, and 3.34±0.36 in the crosshair-artifact region and 2.35±0.31, 2.33±0.31, and 3.09±0.34 in the normal region, for the conventional, MAGIC-SF, and MAGIC-SA techniques, respectively. Conclusion: The introduced MAGIC technique is appropriate for gain calibration of an imaging system associated with a moving FPD and an intrinsic crosshair. The technique showed advantages over a conventional single image-based technique by successfully reducing residual crosshair artifacts, and higher image quality with respect to DQE.« less

Photogrammetric application of viking orbital photography

USGS Publications Warehouse

Wu, S.S.C.; Elassal, A.A.; Jordan, R.; Schafer, F.J.

1982-01-01

Special techniques are described for the photogrammetric compilation of topographic maps and profiles from stereoscopic photographs taken by the two Viking Orbiter spacecraft. These techniques were developed because the extremely narrow field of view of the Viking cameras precludes compilation by conventional photogrammetric methods. The techniques adjust for internal consistency the Supplementary Experiment Data Record (SEDR-the record of spacecraft orientation when photographs were taken) and the computation of geometric orientation parameters of the stereo models. A series of contour maps of Mars is being compiled by these new methods using a wide variety of Viking Orbiter photographs, to provide the planetary research community with topographic information. ?? 1982.

Geodesy and cartography of the Martian satellites

NASA Technical Reports Server (NTRS)

Batson, R. M.; Edwards, Kathleen; Duxbury, T. C.

1992-01-01

The difficulties connected with conventional maps of Phobos and Deimos are largely overcome by producing maps in digital forms, i.e., by projecting Viking Orbiter images onto a global topographic model made from collections of radii derived by photogrammetry. The resulting digital mosaics are then formatted as arrays of body-centered latitudes, longitudes, radii, and brightness values of Viking Orbiter images. The Phobos mapping described was done with Viking Orbiter data. Significant new coverage was obtained by the Soviet Phobos mission. The mapping of Deimos is in progress, using the techniques developed for Phobos.

Optical constants of solid ammonia in the infrared

NASA Technical Reports Server (NTRS)

Robertson, C. W.; Downing, H. D.; Curnutte, B.; Williams, D.

1975-01-01

No direct measurements of the refractive index for solid ammonia could be obtained because of failures in attempts to map the reflection spectrum. Kramers-Kronig techniques were, therefore, used in the investigation. The subtractive Kramers-Kronig techniques employed are similar to those discussed by Ahrenkiel (1971). The subtractive method provides a more-rapid convergence than the conventional techniques when data are available over a limited spectral range.

Preservation of motor maps with increased motor evoked potential amplitude threshold in RMT determination.

PubMed

Lucente, Giuseppe; Lam, Steven; Schneider, Heike; Picht, Thomas

2018-02-01

Non-invasive pre-surgical mapping of eloquent brain areas with navigated transcranial magnetic stimulation (nTMS) is a useful technique linked to the improvement of surgical planning and patient outcomes. The stimulator output intensity and subsequent resting motor threshold determination (rMT) are based on the motor-evoked potential (MEP) elicited in the target muscle with an amplitude above a predetermined threshold of 50 μV. However, a subset of patients is unable to achieve complete relaxation in the target muscles, resulting in false positives that jeopardize mapping validity with conventional MEP determination protocols. Our aim is to explore the feasibility and reproducibility of a novel mapping approach that investigates how an increase of the MEP amplitude threshold to 300 and 500 μV affects subsequent motor maps. Seven healthy subjects underwent motor mapping with nTMS. RMT was calculated with the conventional methodology in conjunction with experimental 300- and 500-μV MEP amplitude thresholds. Motor mapping was performed with 105% of rMT stimulator intensity using the FDI as the target muscle. Motor mapping was possible in all patients with both the conventional and experimental setups. Motor area maps with a conventional 50-μV threshold showed poor correlation with 300-μV (α = 0.446, p < 0.001) maps, but showed excellent consistency with 500-μV motor area maps (α = 0.974, p < 0.001). MEP latencies were significantly less variable (23 ms for 50 μV vs. 23.7 ms for 300 μV vs. 23.7 ms for 500 μV, p < 0.001). A slight but significant increase of the electric field (EF) value was found (EF: 60.8 V/m vs. 64.8 V/m vs. 66 V/m p < 0.001). Our study demonstrates the feasibility of increasing the MEP detection threshold to 500 μV in rMT determination and motor area mapping with nTMS without losing precision.

Use of an Annular Silicon Drift Detector (SDD) Versus a Conventional SDD Makes Phase Mapping a Practical Solution for Rare Earth Mineral Characterization.

PubMed

Teng, Chaoyi; Demers, Hendrix; Brodusch, Nicolas; Waters, Kristian; Gauvin, Raynald

2018-06-04

A number of techniques for the characterization of rare earth minerals (REM) have been developed and are widely applied in the mining industry. However, most of them are limited to a global analysis due to their low spatial resolution. In this work, phase map analyses were performed on REM with an annular silicon drift detector (aSDD) attached to a field emission scanning electron microscope. The optimal conditions for the aSDD were explored, and the high-resolution phase maps generated at a low accelerating voltage identify phases at the micron scale. In comparisons between an annular and a conventional SDD, the aSDD performed at optimized conditions, making the phase map a practical solution for choosing an appropriate grinding size, judging the efficiency of different separation processes, and optimizing a REM beneficiation flowsheet.

Mapping of terrain by computer clustering techniques using multispectral scanner data and using color aerial film

NASA Technical Reports Server (NTRS)

Smedes, H. W.; Linnerud, H. J.; Woolaver, L. B.; Su, M. Y.; Jayroe, R. R.

1972-01-01

Two clustering techniques were used for terrain mapping by computer of test sites in Yellowstone National Park. One test was made with multispectral scanner data using a composite technique which consists of (1) a strictly sequential statistical clustering which is a sequential variance analysis, and (2) a generalized K-means clustering. In this composite technique, the output of (1) is a first approximation of the cluster centers. This is the input to (2) which consists of steps to improve the determination of cluster centers by iterative procedures. Another test was made using the three emulsion layers of color-infrared aerial film as a three-band spectrometer. Relative film densities were analyzed using a simple clustering technique in three-color space. Important advantages of the clustering technique over conventional supervised computer programs are (1) human intervention, preparation time, and manipulation of data are reduced, (2) the computer map, gives unbiased indication of where best to select the reference ground control data, (3) use of easy to obtain inexpensive film, and (4) the geometric distortions can be easily rectified by simple standard photogrammetric techniques.

Quantitative assessment of the T2 relaxation time of the gluteus muscles in children with Duchenne muscular dystrophy: a comparative study before and after steroid treatment.

PubMed

Kim, Hee Kyung; Laor, Tal; Horn, Paul S; Wong, Brenda

2010-01-01

To determine the feasibility of using T2 mapping as a quantitative method to longitudinally follow the disease activity in children with Duchenne muscular dystrophy (DMD) who are treated with steroids. ELEVEN BOYS WITH DMD (AGE RANGE: 5-14 years) underwent evaluation with the clinical functional score (CFS), and conventional pelvic MRI and T2 mapping before and during steroid therapy. The gluteus muscle inflammation and fatty infiltration were evaluated on conventional MRI. The histograms and mean T2 relaxation times were obtained from the T2 maps. The CFS, the conventional MRI findings and the T2 values were compared before and during steroid therapy. None of the patients showed interval change of their CFSs. On conventional MRI, none of the images showed muscle inflammation. During steroid treatment, two boys showed increased fatty infiltration on conventional MRI, and both had an increase of the mean T2 relaxation time (p < 0.05). The remaining nine boys had no increase in fatty infiltration. Of these, three showed an increased mean T2 relaxation time (p < 0.05), two showed no change and four showed a decreased mean T2 relaxation time (p < 0.05). T2 mapping is a feasible technique to evaluate the longitudinal muscle changes in those children who receive steroid therapy for DMD. The differences of the mean T2 relaxation time may reflect alterations in disease activity, and even when the conventional MRI and CFS remain stable.

Gradient-based multiresolution image fusion.

PubMed

Petrović, Valdimir S; Xydeas, Costas S

2004-02-01

A novel approach to multiresolution signal-level image fusion is presented for accurately transferring visual information from any number of input image signals, into a single fused image without loss of information or the introduction of distortion. The proposed system uses a "fuse-then-decompose" technique realized through a novel, fusion/decomposition system architecture. In particular, information fusion is performed on a multiresolution gradient map representation domain of image signal information. At each resolution, input images are represented as gradient maps and combined to produce new, fused gradient maps. Fused gradient map signals are processed, using gradient filters derived from high-pass quadrature mirror filters to yield a fused multiresolution pyramid representation. The fused output image is obtained by applying, on the fused pyramid, a reconstruction process that is analogous to that of conventional discrete wavelet transform. This new gradient fusion significantly reduces the amount of distortion artefacts and the loss of contrast information usually observed in fused images obtained from conventional multiresolution fusion schemes. This is because fusion in the gradient map domain significantly improves the reliability of the feature selection and information fusion processes. Fusion performance is evaluated through informal visual inspection and subjective psychometric preference tests, as well as objective fusion performance measurements. Results clearly demonstrate the superiority of this new approach when compared to conventional fusion systems.

[Technical notes on mastectomy performed as part of transsexualism F to M].

PubMed

Roffé, J-L

2012-08-01

Mastectomy in case of large breast should use a particular technique. The principle of mastectomy by periareolar flap or higher in MAP must be abandoned in favor of mastectomy by lower horizontal with the office of the WFP transformed by a tummy. Main technical note contains the plasty in MAP because the conventional mastectomy is well known. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

Automated strip-mine and reclamation mapping from ERTS

NASA Technical Reports Server (NTRS)

Rogers, R. H. (Principal Investigator); Reed, L. E.; Pettyjohn, W. A.

1974-01-01

The author has identified the following significant results. Computer processing techniques were applied to ERTS-1 computer-compatible tape (CCT) data acquired in August 1972 on the Ohio Power Company's coal mining operation in Muskingum County, Ohio. Processing results succeeded in automatically classifying, with an accuracy greater than 90%: (1) stripped earth and major sources of erosion; (2) partially reclaimed areas and minor sources of erosion; (3) water with sedimentation; (4) water without sedimentation; and (5) vegetation. Computer-generated tables listing the area in acres and square kilometers were produced for each target category. Processing results also included geometrically corrected map overlays, one for each target category, drawn on a transparent material by a pen under computer control. Each target category is assigned a distinctive color on the overlay to facilitate interpretation. The overlays, drawn at a scale of 1:250,000 when placed over an AMS map of the same area, immediately provided map locations for each target. These mapping products were generated at a tenth of the cost of conventional mapping techniques.

Tomographic diffractive microscopy with a wavefront sensor.

PubMed

Ruan, Y; Bon, P; Mudry, E; Maire, G; Chaumet, P C; Giovannini, H; Belkebir, K; Talneau, A; Wattellier, B; Monneret, S; Sentenac, A

2012-05-15

Tomographic diffractive microscopy is a recent imaging technique that reconstructs quantitatively the three-dimensional permittivity map of a sample with a resolution better than that of conventional wide-field microscopy. Its main drawbacks lie in the complexity of the setup and in the slowness of the image recording as both the amplitude and the phase of the field scattered by the sample need to be measured for hundreds of successive illumination angles. In this Letter, we show that, using a wavefront sensor, tomographic diffractive microscopy can be implemented easily on a conventional microscope. Moreover, the number of illuminations can be dramatically decreased if a constrained reconstruction algorithm is used to recover the sample map of permittivity.

A Probabilistic Feature Map-Based Localization System Using a Monocular Camera.

PubMed

Kim, Hyungjin; Lee, Donghwa; Oh, Taekjun; Choi, Hyun-Taek; Myung, Hyun

2015-08-31

Image-based localization is one of the most widely researched localization techniques in the robotics and computer vision communities. As enormous image data sets are provided through the Internet, many studies on estimating a location with a pre-built image-based 3D map have been conducted. Most research groups use numerous image data sets that contain sufficient features. In contrast, this paper focuses on image-based localization in the case of insufficient images and features. A more accurate localization method is proposed based on a probabilistic map using 3D-to-2D matching correspondences between a map and a query image. The probabilistic feature map is generated in advance by probabilistic modeling of the sensor system as well as the uncertainties of camera poses. Using the conventional PnP algorithm, an initial camera pose is estimated on the probabilistic feature map. The proposed algorithm is optimized from the initial pose by minimizing Mahalanobis distance errors between features from the query image and the map to improve accuracy. To verify that the localization accuracy is improved, the proposed algorithm is compared with the conventional algorithm in a simulation and realenvironments.

A Probabilistic Feature Map-Based Localization System Using a Monocular Camera

PubMed Central

Kim, Hyungjin; Lee, Donghwa; Oh, Taekjun; Choi, Hyun-Taek; Myung, Hyun

2015-01-01

Image-based localization is one of the most widely researched localization techniques in the robotics and computer vision communities. As enormous image data sets are provided through the Internet, many studies on estimating a location with a pre-built image-based 3D map have been conducted. Most research groups use numerous image data sets that contain sufficient features. In contrast, this paper focuses on image-based localization in the case of insufficient images and features. A more accurate localization method is proposed based on a probabilistic map using 3D-to-2D matching correspondences between a map and a query image. The probabilistic feature map is generated in advance by probabilistic modeling of the sensor system as well as the uncertainties of camera poses. Using the conventional PnP algorithm, an initial camera pose is estimated on the probabilistic feature map. The proposed algorithm is optimized from the initial pose by minimizing Mahalanobis distance errors between features from the query image and the map to improve accuracy. To verify that the localization accuracy is improved, the proposed algorithm is compared with the conventional algorithm in a simulation and realenvironments. PMID:26404284

Enhanced in vivo visualization of the microcirculation by topical application of fructose solution confirmed with correlation mapping optical coherence tomography

NASA Astrophysics Data System (ADS)

Enfield, Joey; McGrath, James; Daly, Susan M.; Leahy, Martin

2016-08-01

Changes within the microcirculation can provide an early indication of the onset of a plethora of ailments. Various techniques have thus been developed that enable the study of microcirculatory irregularities. Correlation mapping optical coherence tomography (cmOCT) is a recently proposed technique, which enables mapping of vasculature networks at the capillary level in a noninvasive and noncontact manner. This technique is an extension of conventional optical coherence tomography (OCT) and is therefore likewise limited in the penetration depth of ballistic photons in biological media. Optical clearing has previously been demonstrated to enhance the penetration depth and the imaging capabilities of OCT. In order to enhance the achievable maximum imaging depth, we propose the use of optical clearing in conjunction with the cmOCT technique. We demonstrate in vivo a 13% increase in OCT penetration depth by topical application of a high-concentration fructose solution, thereby enabling the visualization of vessel features at deeper depths within the tissue.

An Improved Map-Matching Technique Based on the Fréchet Distance Approach for Pedestrian Navigation Services

PubMed Central

Bang, Yoonsik; Kim, Jiyoung; Yu, Kiyun

2016-01-01

Wearable and smartphone technology innovations have propelled the growth of Pedestrian Navigation Services (PNS). PNS need a map-matching process to project a user’s locations onto maps. Many map-matching techniques have been developed for vehicle navigation services. These techniques are inappropriate for PNS because pedestrians move, stop, and turn in different ways compared to vehicles. In addition, the base map data for pedestrians are more complicated than for vehicles. This article proposes a new map-matching method for locating Global Positioning System (GPS) trajectories of pedestrians onto road network datasets. The theory underlying this approach is based on the Fréchet distance, one of the measures of geometric similarity between two curves. The Fréchet distance approach can provide reasonable matching results because two linear trajectories are parameterized with the time variable. Then we improved the method to be adaptive to the positional error of the GPS signal. We used an adaptation coefficient to adjust the search range for every input signal, based on the assumption of auto-correlation between consecutive GPS points. To reduce errors in matching, the reliability index was evaluated in real time for each match. To test the proposed map-matching method, we applied it to GPS trajectories of pedestrians and the road network data. We then assessed the performance by comparing the results with reference datasets. Our proposed method performed better with test data when compared to a conventional map-matching technique for vehicles. PMID:27782091

Phenotypic mutant library: potential for gene discovery

USDA-ARS?s Scientific Manuscript database

The rapid development of high throughput and affordable Next- Generation Sequencing (NGS) techniques has renewed interest in gene discovery using forward genetics. The conventional forward genetic approach starts with isolation of mutants with a phenotype of interest, mapping the mutation within a s...

Automatic mapping of strip mine operations from spacecraft data. [Ohio

NASA Technical Reports Server (NTRS)

Rogers, R. H. (Principal Investigator); Reed, L. E.; Pettyjohn, W. A.

1974-01-01

The author has identified the following significant results. Computer techniques were applied to process ERTS tapes acquired over coal mining operations in southeastern Ohio on 21 August 1972 and 3 September 1973. ERTS products obtained included geometrically-correct map overlays, at scales from 1:24,000 to 1:250,000, showing stripped earth, partially reclaimed earth, water, and natural vegetation. Computer-generated tables listing the area covered by each land-water category in square kilometers were also produced. By comparing these mapping products, the study demonstrates the capability of ERTS to monitor changes in the extent of stripping and reclamation. NASA C-130 photography acquired on 7 September 1973 when compared with the ERTS products generated from the 3 September 1973 tape established the categorization accuracy to be better than 90%. It is estimated that the stripping and reclamation maps and data were produced from the ERTS CCTs at a tenth of the cost of conventional techniques.

Cartography of irregularly shaped satellites

NASA Technical Reports Server (NTRS)

Batson, R. M.; Edwards, Kathleen

1987-01-01

Irregularly shaped satellites, such as Phobos and Amalthea, do not lend themselves to mapping by conventional methods because mathematical projections of their surfaces fail to convey an accurate visual impression of the landforms, and because large and irregular scale changes make their features difficult to measure on maps. A digital mapping technique has therefore been developed by which maps are compiled from digital topographic and spacecraft image files. The digital file is geometrically transformed as desired for human viewing, either on video screens or on hard copy. Digital files of this kind consist of digital images superimposed on another digital file representing the three-dimensional form of a body.

Landsat for practical forest type mapping - A test case

NASA Technical Reports Server (NTRS)

Bryant, E.; Dodge, A. G., Jr.; Warren, S. D.

1980-01-01

Computer classified Landsat maps are compared with a recent conventional inventory of forest lands in northern Maine. Over the 196,000 hectare area mapped, estimates of the areas of softwood, mixed wood and hardwood forest obtained by a supervised classification of the Landsat data and a standard inventory based on aerial photointerpretation, probability proportional to prediction, field sampling and a standard forest measurement program are found to agree to within 5%. The cost of the Landsat maps is estimated to be $0.065/hectare. It is concluded that satellite techniques are worth developing for forest inventories, although they are not yet refined enough to be incorporated into current practical inventories.

Evaluation of aircraft microwave data for locating zones for well stimulation and enhanced gas recovery. [Arkansas Arkoma Basin

NASA Technical Reports Server (NTRS)

Macdonald, H.; Waite, W.; Elachi, C.; Babcock, R.; Konig, R.; Gattis, J.; Borengasser, M.; Tolman, D.

1980-01-01

Imaging radar was evaluated as an adjunct to conventional petroleum exploration techniques, especially linear mapping. Linear features were mapped from several remote sensor data sources including stereo photography, enhanced LANDSAT imagery, SLAR radar imagery, enhanced SAR radar imagery, and SAR radar/LANDSAT combinations. Linear feature maps were compared with surface joint data, subsurface and geophysical data, and gas production in the Arkansas part of the Arkoma basin. The best LANDSAT enhanced product for linear detection was found to be a winter scene, band 7, uniform distribution stretch. Of the individual SAR data products, the VH (cross polarized) SAR radar mosaic provides for detection of most linears; however, none of the SAR enhancements is significantly better than the others. Radar/LANDSAT merges may provide better linear detection than a single sensor mapping mode, but because of operator variability, the results are inconclusive. Radar/LANDSAT combinations appear promising as an optimum linear mapping technique, if the advantages and disadvantages of each remote sensor are considered.

Clitoral Epidermal Inclusion Cyst Resection With Intraoperative Sensory Nerve Mapping Technique.

PubMed

Wu, Cindy; Damitz, Lynn; Karrat, Kimberly M; Mintz, Alice; Zolnoun, Denniz

2016-01-01

Despite the ever increasing popularity of labial and clitoral surgeries, the best practices and long-term effects of reconstructive procedures in these regions remain unknown. This is particularly noteworthy because the presentation of nerve-related symptoms may be delayed up to a year. Despite the convention that these surgical procedures are low risk, little is known about the best practices that may reduce the postoperative complications as a result of these reconstructive surgeries. We describe a preoperative sensory mapping technique in the context of a symptomatic inclusion cyst in the clitoral region. This technique delineates anatomical and functional regions innervated by the dorsal clitoral nerve while minimizing the vascular watershed area in the midline. A prototypical case of a patient with a clitoral mass is discussed with clinical history and surgical approach. Prior to surgical excision, the dorsal clitoral nerve distribution was mapped in order to avoid a surgical incision in this sensual zone. In our practice, preoperative sensory mapping is a clinically useful planning tool that requires minimal instrumentation and no additional operating time. Sensory mapping allows identification of the functional zone innervated by the dorsal clitoral nerve, which can aid in minimizing damage to the area.

A multispectral study of an extratropical cyclone with Nimbus 3 medium resolution infrared radiometer data

NASA Technical Reports Server (NTRS)

Holub, R.; Shenk, W. E.

1973-01-01

Four registered channels (0.2 to 4, 6.5 to 7, 10 to 11, and 20 to 23 microns) of the Nimbus 3 Medium Resolution Infrared Radiometer (MRIR) were used to study 24-hr changes in the structure of an extratropical cyclone during a 6-day period in May 1969. Use of a stereographic-horizon map projection insured that the storm was mapped with a single perspective throughout the series and allowed the convenient preparation of 24-hr difference maps of the infrared radiation fields. Single-channel and multispectral analysis techniques were employed to establish the positions and vertical slopes of jetstreams, large cloud systems, and major features of middle and upper tropospheric circulation. Use of these techniques plus the difference maps and continuity of observation allowed the early detection of secondary cyclones developing within the circulation of the primary cyclone. An automated, multispectral cloud-type identification technique was developed, and comparisons that were made with conventional ship reports and with high-resolution visual data from the image dissector camera system showed good agreement.

Backwards compatible high dynamic range video compression

NASA Astrophysics Data System (ADS)

Dolzhenko, Vladimir; Chesnokov, Vyacheslav; Edirisinghe, Eran A.

2014-02-01

This paper presents a two layer CODEC architecture for high dynamic range video compression. The base layer contains the tone mapped video stream encoded with 8 bits per component which can be decoded using conventional equipment. The base layer content is optimized for rendering on low dynamic range displays. The enhancement layer contains the image difference, in perceptually uniform color space, between the result of inverse tone mapped base layer content and the original video stream. Prediction of the high dynamic range content reduces the redundancy in the transmitted data while still preserves highlights and out-of-gamut colors. Perceptually uniform colorspace enables using standard ratedistortion optimization algorithms. We present techniques for efficient implementation and encoding of non-uniform tone mapping operators with low overhead in terms of bitstream size and number of operations. The transform representation is based on human vision system model and suitable for global and local tone mapping operators. The compression techniques include predicting the transform parameters from previously decoded frames and from already decoded data for current frame. Different video compression techniques are compared: backwards compatible and non-backwards compatible using AVC and HEVC codecs.

Venus Quadrangle Geological Mapping: Use of Geoscience Data Visualization Systems in Mapping and Training

NASA Technical Reports Server (NTRS)

Head, James W.; Huffman, J. N.; Forsberg, A. S.; Hurwitz, D. M.; Basilevsky, A. T.; Ivanov, M. A.; Dickson, J. L.; Kumar, P. Senthil

2008-01-01

We are currently investigating new technological developments in computer visualization and analysis in order to assess their importance and utility in planetary geological analysis and mapping [1,2]. Last year we reported on the range of technologies available and on our application of these to various problems in planetary mapping [3]. In this contribution we focus on the application of these techniques and tools to Venus geological mapping at the 1:5M quadrangle scale. In our current Venus mapping projects we have utilized and tested the various platforms to understand their capabilities and assess their usefulness in defining units, establishing stratigraphic relationships, mapping structures, reaching consensus on interpretations and producing map products. We are specifically assessing how computer visualization display qualities (e.g., level of immersion, stereoscopic vs. monoscopic viewing, field of view, large vs. small display size, etc.) influence performance on scientific analysis and geological mapping. We have been exploring four different environments: 1) conventional desktops (DT), 2) semi-immersive Fishtank VR (FT) (i.e., a conventional desktop with head-tracked stereo and 6DOF input), 3) tiled wall displays (TW), and 4) fully immersive virtual reality (IVR) (e.g., "Cave Automatic Virtual Environment," or Cave system). Formal studies demonstrate that fully immersive Cave environments are superior to desktop systems for many tasks [e.g., 4].

Comparison of intraoral scanning and conventional impression techniques using 3-dimensional superimposition.

PubMed

Rhee, Ye-Kyu; Huh, Yoon-Hyuk; Cho, Lee-Ra; Park, Chan-Jin

2015-12-01

The aim of this study is to evaluate the appropriate impression technique by analyzing the superimposition of 3D digital model for evaluating accuracy of conventional impression technique and digital impression. Twenty-four patients who had no periodontitis or temporomandibular joint disease were selected for analysis. As a reference model, digital impressions with a digital impression system were performed. As a test models, for conventional impression dual-arch and full-arch, impression techniques utilizing addition type polyvinylsiloxane for fabrication of cast were applied. 3D laser scanner is used for scanning the cast. Each 3 pairs for 25 STL datasets were imported into the inspection software. The three-dimensional differences were illustrated in a color-coded map. For three-dimensional quantitative analysis, 4 specified contact locations(buccal and lingual cusps of second premolar and molar) were established. For twodimensional quantitative analysis, the sectioning from buccal cusp to lingual cusp of second premolar and molar were acquired depending on the tooth axis. In color-coded map, the biggest difference between intraoral scanning and dual-arch impression was seen (P<.05). In three-dimensional analysis, the biggest difference was seen between intraoral scanning and dual-arch impression and the smallest difference was seen between dual-arch and full-arch impression. The two- and three-dimensional deviations between intraoral scanner and dual-arch impression was bigger than full-arch and dual-arch impression (P<.05). The second premolar showed significantly bigger three-dimensional deviations than the second molar in the three-dimensional deviations (P>.05).

Comparison of intraoral scanning and conventional impression techniques using 3-dimensional superimposition

PubMed Central

Rhee, Ye-Kyu

2015-01-01

PURPOSE The aim of this study is to evaluate the appropriate impression technique by analyzing the superimposition of 3D digital model for evaluating accuracy of conventional impression technique and digital impression. MATERIALS AND METHODS Twenty-four patients who had no periodontitis or temporomandibular joint disease were selected for analysis. As a reference model, digital impressions with a digital impression system were performed. As a test models, for conventional impression dual-arch and full-arch, impression techniques utilizing addition type polyvinylsiloxane for fabrication of cast were applied. 3D laser scanner is used for scanning the cast. Each 3 pairs for 25 STL datasets were imported into the inspection software. The three-dimensional differences were illustrated in a color-coded map. For three-dimensional quantitative analysis, 4 specified contact locations(buccal and lingual cusps of second premolar and molar) were established. For twodimensional quantitative analysis, the sectioning from buccal cusp to lingual cusp of second premolar and molar were acquired depending on the tooth axis. RESULTS In color-coded map, the biggest difference between intraoral scanning and dual-arch impression was seen (P<.05). In three-dimensional analysis, the biggest difference was seen between intraoral scanning and dual-arch impression and the smallest difference was seen between dual-arch and full-arch impression. CONCLUSION The two- and three-dimensional deviations between intraoral scanner and dual-arch impression was bigger than full-arch and dual-arch impression (P<.05). The second premolar showed significantly bigger three-dimensional deviations than the second molar in the three-dimensional deviations (P>.05). PMID:26816576

Spatial and Global Sensory Suppression Mapping Encompassing the Central 10° Field in Anisometropic Amblyopia.

PubMed

Li, Jingjing; Li, Jinrong; Chen, Zidong; Liu, Jing; Yuan, Junpeng; Cai, Xiaoxiao; Deng, Daming; Yu, Minbin

2017-01-01

We investigate the efficacy of a novel dichoptic mapping paradigm in evaluating visual function of anisometropic amblyopes. Using standard clinical measures of visual function (visual acuity, stereo acuity, Bagolini lenses, and neutral density filters) and a novel quantitative mapping technique, 26 patients with anisometropic amblyopia (mean age = 19.15 ± 4.42 years) were assessed. Two additional psychophysical interocular suppression measurements were tested with dichoptic global motion coherence and binocular phase combination tasks. Luminance reduction was achieved by placing neutral density filters in front of the normal eye. Our study revealed that suppression changes across the central 10° visual field by mean luminance modulation in amblyopes as well as normal controls. Using simulation and an elimination of interocular suppression, we identified a novel method to effectively reflect the distribution of suppression in anisometropic amblyopia. Additionally, the new quantitative mapping technique was in good agreement with conventional clinical measures, such as interocular acuity difference (P < 0.001) and stereo acuity (P = 0.005). There was a good consistency between the results of interocular suppression with dichoptic mapping paradigm and the results of the other two psychophysical methods (suppression mapping versus binocular phase combination, P < 0.001; suppression mapping versus global motion coherence, P = 0.005). The dichoptic suppression mapping technique is an effective method to represent impaired visual function in patients with anisometropic amblyopia. It offers a potential in "micro-"antisuppression mapping tests and therapies for amblyopia.

Application of Satellite SAR Imagery in Mapping the Active Layer of Arctic Permafrost

NASA Technical Reports Server (NTRS)

Li, Shu-Sun; Romanovsky, V.; Lovick, Joe; Wang, Z.; Peterson, Rorik

2003-01-01

A method of mapping the active layer of Arctic permafrost using a combination of conventional synthetic aperture radar (SAR) backscatter and more sophisticated interferometric SAR (INSAR) techniques is proposed. The proposed research is based on the sensitivity of radar backscatter to the freeze and thaw status of the surface soil, and the sensitivity of INSAR techniques to centimeter- to sub-centimeter-level surface differential deformation. The former capability of SAR is investigated for deriving the timing and duration of the thaw period for surface soil of the active layer over permafrost. The latter is investigated for the feasibility of quantitative measurement of frost heaving and thaw settlement of the active layer during the freezing and thawing processes. The resulting knowledge contributes to remote sensing mapping of the active layer dynamics and Arctic land surface hydrology.

Covariance mapping of two-photon double core hole states in C 2 H 2 and C 2 H 6 produced by an x-ray free electron laser

DOE PAGES

Mucke, M; Zhaunerchyk, V; Frasinski, L J; ...

2015-07-01

Few-photon ionization and relaxation processes in acetylene (C 2H 2) and ethane (C 2H 6) were investigated at the linac coherent light source x-ray free electron laser (FEL) at SLAC, Stanford using a highly efficient multi-particle correlation spectroscopy technique based on a magnetic bottle. The analysis method of covariance mapping has been applied and enhanced, allowing us to identify electron pairs associated with double core hole (DCH) production and competing multiple ionization processes including Auger decay sequences. The experimental technique and the analysis procedure are discussed in the light of earlier investigations of DCH studies carried out at the samemore » FEL and at third generation synchrotron radiation sources. In particular, we demonstrate the capability of the covariance mapping technique to disentangle the formation of molecular DCH states which is barely feasible with conventional electron spectroscopy methods.« less

Validation of Innovative Exploration Technologies for Newberry Volcano: Drill Site Location Map 2010

DOE Data Explorer

Jaffe, Todd

2012-01-01

Newberry seeks to explore "blind" (no surface evidence) convective hydrothermal systems associated with a young silicic pluton on the flanks of Newberry Volcano. This project will employ a combination of innovative and conventional techniques to identify the location of subsurface geothermal fluids associated with the hot pluton. Newberry project drill site location map 2010. Once the exploration mythology is validated, it can be applied throughout the Cascade Range and elsewhere to locate and develop “blind” geothermal resources.

Interpretation of ERTS-MSS images of a Savanna area in eastern Colombia

NASA Technical Reports Server (NTRS)

Elberson, G. W. W.

1973-01-01

The application of ERTS-1 imagery for extrapolating existing soil maps into unmapped areas of the Llanos Orientales of Colombia, South America is discussed. Interpretations of ERTS-1 data were made according to conventional photointerpretation techniques. Most units delineated in the existing reconnaissance soil map at a scale of 1:250,000 could be recognized and delineated in the ERTS image. The methods of interpretation are described and the results obtained for specific areas are analyzed.

Secure positioning technique based on encrypted visible light map for smart indoor service

NASA Astrophysics Data System (ADS)

Lee, Yong Up; Jung, Gillyoung

2018-03-01

Indoor visible light (VL) positioning systems for smart indoor services are negatively affected by both cochannel interference from adjacent light sources and VL reception position irregularity in the three-dimensional (3-D) VL channel. A secure positioning methodology based on a two-dimensional (2-D) encrypted VL map is proposed, implemented in prototypes of the specific positioning system, and analyzed based on performance tests. The proposed positioning technique enhances the positioning performance by more than 21.7% compared to the conventional method in real VL positioning tests. Further, the pseudonoise code is found to be the optimal encryption key for secure VL positioning for this smart indoor service.

Improving acoustic beamforming maps in a reverberant environment by modifying the cross-correlation matrix

NASA Astrophysics Data System (ADS)

Fischer, J.; Doolan, C.

2017-12-01

A method to improve the quality of acoustic beamforming in reverberant environments is proposed in this paper. The processing is based on a filtering of the cross-correlation matrix of the microphone signals obtained using a microphone array. The main advantage of the proposed method is that it does not require information about the geometry of the reverberant environment and thus it can be applied to any configuration. The method is applied to the particular example of aeroacoustic testing in a hard-walled low-speed wind tunnel; however, the technique can be used in any reverberant environment. Two test cases demonstrate the technique. The first uses a speaker placed in the hard-walled working section with no wind tunnel flow. In the second test case, an airfoil is placed in a flow and acoustic beamforming maps are obtained. The acoustic maps have been improved, as the reflections observed in the conventional maps have been removed after application of the proposed method.

Performance analysis of a finite radon transform in OFDM system under different channel models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dawood, Sameer A.; Anuar, M. S.; Fayadh, Rashid A.

In this paper, a class of discrete Radon transforms namely Finite Radon Transform (FRAT) was proposed as a modulation technique in the realization of Orthogonal Frequency Division Multiplexing (OFDM). The proposed FRAT operates as a data mapper in the OFDM transceiver instead of the conventional phase shift mapping and quadrature amplitude mapping that are usually used with the standard OFDM based on Fast Fourier Transform (FFT), by the way that ensure increasing the orthogonality of the system. The Fourier domain approach was found here to be the more suitable way for obtaining the forward and inverse FRAT. This structure resultedmore » in a more suitable realization of conventional FFT- OFDM. It was shown that this application increases the orthogonality significantly in this case due to the use of Inverse Fast Fourier Transform (IFFT) twice, namely, in the data mapping and in the sub-carrier modulation also due to the use of an efficient algorithm in determining the FRAT coefficients called the optimal ordering method. The proposed approach was tested and compared with conventional OFDM, for additive white Gaussian noise (AWGN) channel, flat fading channel, and multi-path frequency selective fading channel. The obtained results showed that the proposed system has improved the bit error rate (BER) performance by reducing inter-symbol interference (ISI) and inter-carrier interference (ICI), comparing with conventional OFDM system.« less

Performance analysis of a finite radon transform in OFDM system under different channel models

NASA Astrophysics Data System (ADS)

Dawood, Sameer A.; Malek, F.; Anuar, M. S.; Fayadh, Rashid A.; Abdullah, Farrah Salwani

2015-05-01

In this paper, a class of discrete Radon transforms namely Finite Radon Transform (FRAT) was proposed as a modulation technique in the realization of Orthogonal Frequency Division Multiplexing (OFDM). The proposed FRAT operates as a data mapper in the OFDM transceiver instead of the conventional phase shift mapping and quadrature amplitude mapping that are usually used with the standard OFDM based on Fast Fourier Transform (FFT), by the way that ensure increasing the orthogonality of the system. The Fourier domain approach was found here to be the more suitable way for obtaining the forward and inverse FRAT. This structure resulted in a more suitable realization of conventional FFT- OFDM. It was shown that this application increases the orthogonality significantly in this case due to the use of Inverse Fast Fourier Transform (IFFT) twice, namely, in the data mapping and in the sub-carrier modulation also due to the use of an efficient algorithm in determining the FRAT coefficients called the optimal ordering method. The proposed approach was tested and compared with conventional OFDM, for additive white Gaussian noise (AWGN) channel, flat fading channel, and multi-path frequency selective fading channel. The obtained results showed that the proposed system has improved the bit error rate (BER) performance by reducing inter-symbol interference (ISI) and inter-carrier interference (ICI), comparing with conventional OFDM system.

Fluorescence spectroscopy using indocyanine green for lymph node mapping

NASA Astrophysics Data System (ADS)

Haj-Hosseini, Neda; Behm, Pascal; Shabo, Ivan; Wârdell, Karin

2014-02-01

The principles of cancer treatment has for years been radical resection of the primary tumor. In the oncologic surgeries where the affected cancer site is close to the lymphatic system, it is as important to detect the draining lymph nodes for metastasis (lymph node mapping). As a replacement for conventional radioactive labeling, indocyanine green (ICG) has shown successful results in lymph node mapping; however, most of the ICG fluorescence detection techniques developed are based on camera imaging. In this work, fluorescence spectroscopy using a fiber-optical probe was evaluated on a tissue-like ICG phantom with ICG concentrations of 6-64 μM and on breast tissue from five patients. Fiber-optical based spectroscopy was able to detect ICG fluorescence at low intensities; therefore, it is expected to increase the detection threshold of the conventional imaging systems when used intraoperatively. The probe allows spectral characterization of the fluorescence and navigation in the tissue as opposed to camera imaging which is limited to the view on the surface of the tissue.

Mass Spectrometric and Synchrotron Radiation based techniques for the identification and distribution of painting materials in samples from paints of Josep Maria Sert

PubMed Central

2012-01-01

Background Establishing the distribution of materials in paintings and that of their degradation products by imaging techniques is fundamental to understand the painting technique and can improve our knowledge on the conservation status of the painting. The combined use of chromatographic-mass spectrometric techniques, such as GC/MS or Py/GC/MS, and the chemical mapping of functional groups by imaging SR FTIR in transmission mode on thin sections and SR XRD line scans will be presented as a suitable approach to have a detailed characterisation of the materials in a paint sample, assuring their localisation in the sample build-up. This analytical approach has been used to study samples from Catalan paintings by Josep Maria Sert y Badía (20th century), a muralist achieving international recognition whose canvases adorned international buildings. Results The pigments used by the painter as well as the organic materials used as binders and varnishes could be identified by means of conventional techniques. The distribution of these materials by means of Synchrotron Radiation based techniques allowed to establish the mixtures used by the painter depending on the purpose. Conclusions Results show the suitability of the combined use of SR μFTIR and SR μXRD mapping and conventional techniques to unequivocally identify all the materials present in the sample and their localization in the sample build-up. This kind of approach becomes indispensable to solve the challenge of micro heterogeneous samples. The complementary interpretation of the data obtained with all the different techniques allowed the characterization of both organic and inorganic materials in the samples layer by layer as well as to establish the painting techniques used by Sert in the works-of-art under study. PMID:22616949

Evaluation of EREP techniques for geological mapping. [southern Pyrenees and Ebro basin in Spain

NASA Technical Reports Server (NTRS)

Vandermeermohr, H. E. C.; Srivastava, G. S. (Principal Investigator)

1975-01-01

The author has identified the following significant results. Skylab photographs may be successfully utilized for preparing a reconnaissance geological map in the areas where no maps or semi-detailed maps exist. Large coverage of area and regional perspective from Skylab photographs can help better coordination in regional mapping. It is possible to delineate major structural trends and other features like mega-lineaments, geofractures, and faults, which have evaded their detection by conventional methods. The photointerpretability is better in areas dominated by sedimentary rocks. Rock units of smaller extent and having poor geomorphic expressions are difficult to map. Demarcation of quaternary river alluvium can be made with better precision and ease with the Skylab photographs. Stereoscopic viewing greatly helps in interpretation of area structures. Skylab photographs are not good for preparing geological maps larger than 1:270,000 scale.

Improving IMRT delivery efficiency with reweighted L1-minimization for inverse planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Hojin; Becker, Stephen; Lee, Rena

2013-07-15

Purpose: This study presents an improved technique to further simplify the fluence-map in intensity modulated radiation therapy (IMRT) inverse planning, thereby reducing plan complexity and improving delivery efficiency, while maintaining the plan quality.Methods: First-order total-variation (TV) minimization (min.) based on L1-norm has been proposed to reduce the complexity of fluence-map in IMRT by generating sparse fluence-map variations. However, with stronger dose sparing to the critical structures, the inevitable increase in the fluence-map complexity can lead to inefficient dose delivery. Theoretically, L0-min. is the ideal solution for the sparse signal recovery problem, yet practically intractable due to its nonconvexity of themore » objective function. As an alternative, the authors use the iteratively reweighted L1-min. technique to incorporate the benefits of the L0-norm into the tractability of L1-min. The weight multiplied to each element is inversely related to the magnitude of the corresponding element, which is iteratively updated by the reweighting process. The proposed penalizing process combined with TV min. further improves sparsity in the fluence-map variations, hence ultimately enhancing the delivery efficiency. To validate the proposed method, this work compares three treatment plans obtained from quadratic min. (generally used in clinic IMRT), conventional TV min., and our proposed reweighted TV min. techniques, implemented by a large-scale L1-solver (template for first-order conic solver), for five patient clinical data. Criteria such as conformation number (CN), modulation index (MI), and estimated treatment time are employed to assess the relationship between the plan quality and delivery efficiency.Results: The proposed method yields simpler fluence-maps than the quadratic and conventional TV based techniques. To attain a given CN and dose sparing to the critical organs for 5 clinical cases, the proposed method reduces the number of segments by 10-15 and 30-35, relative to TV min. and quadratic min. based plans, while MIs decreases by about 20%-30% and 40%-60% over the plans by two existing techniques, respectively. With such conditions, the total treatment time of the plans obtained from our proposed method can be reduced by 12-30 s and 30-80 s mainly due to greatly shorter multileaf collimator (MLC) traveling time in IMRT step-and-shoot delivery.Conclusions: The reweighted L1-minimization technique provides a promising solution to simplify the fluence-map variations in IMRT inverse planning. It improves the delivery efficiency by reducing the entire segments and treatment time, while maintaining the plan quality in terms of target conformity and critical structure sparing.« less

Non-coincident Inter-instrument Comparisons of Ozone Measurements Using Quasi-conservative Coordinates

NASA Technical Reports Server (NTRS)

Lait, L. R.; Newman, P. A.; Schoeberl, M. R.; McGee, T.; Twigg, T.; Browell, E.; Bevilacqua, R.; Andersen, S. B.; DeBacker, H.; Benesova, A.

2004-01-01

Ozone measurements from ozonesondes, AROTAL, DIAL, and POAM III instruments during the SOLVE-2/VINTERSOL period are composited in a time-varying, flow-following quasi-conservative (PV-6) coordinate space; the resulting composites from each instrument are mapped onto the other instruments locations and times. The mapped data are then used to intercompare data from the different instruments. Overall, the four data sets are found to be in good agreement. AROTAL shows somewhat lower values below 16 km, and DIAL has a positive bias at the upper limits of its altitude range. These intercomparisons are consistent with those obtained from more conventional near-coincident profiles, where available. Although the PV-theta mapping technique entails larger uncertainties of individual profile differences compared to direct near-coincident comparisons, the ability to include much larger numbers of comparisons can make this technique advantageous.

A Concept-Mapping Strategy for Assessing Conceptual Change in a Student-Directed, Research-Based Geoscience Course

NASA Astrophysics Data System (ADS)

Rebich, S.

2003-12-01

The concept mapping technique has been proposed as a method for examining the evolving nature of students' conceptualizations of scientific concepts, and promises insight into a dimension of learning different from the one accessible through more conventional classroom testing techniques. The theory behind concept mapping is based on an assumption that knowledge acquisition is accomplished through "linking" of new information to an existing knowledge framework, and that meaningful (as opposed to arbitrary or verbatim) links allow for deeper understanding and conceptual change. Reflecting this theory, concept maps are constructed as a network of related concepts connected by labeled links that illustrate the relationship between the concepts. Two concepts connected by one such link make up a "proposition", the basic element of the concept map structure. In this paper, we examine the results of a pre- and post-test assessment program for an upper-division undergraduate geography course entitled "Mock Environmental Summit," which was part of a research project on assessment. Concept mapping was identified as a potentially powerful assessment tool for this course, as more conventional tools such as multiple-choice tests did not seem to provide a reliable indication of the learning students were experiencing as a result of the student-directed research, presentations, and discussions that make up a substantial portion of the course. The assessment program began at the beginning of the course with a one-hour training session during which students were introduced to the theory behind concept mapping, provided with instructions and guidance for constructing a concept map using the CMap software developed and maintained by the Institute for Human and Machine Cognition at the University of West Florida, and asked to collaboratively construct a concept map on a topic not related to the one to be assessed. This training session was followed by a 45-minute "pre-test" on the topic of global climate change, for which students were provided with a list of questions to guide their thoughts during the concept map construction. Following the pre-test, students were not exposed to further concept mapping until the end of the course, when they were asked to complete a "post-test" consisting of exactly the same task. In addition to a summary of our results, this paper presents an overview of available digital concept-mapping tools, proposed scoring techniques, and design principles to keep in mind when designing a concept-mapping assessment program. We also discuss our experience with concept map assessment, the insights it provided into the evolution in student understanding of global climate change that resulted from the course, and our ideas about the potential role of concept mapping in an overall assessment program for interdisciplinary and/or student-directed curricula.

SU-E-T-269: Differential Hazard Analysis For Conventional And New Linac Acceptance Testing Procedures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harry, T; Yaddanapudi, S; Mutic, S

Purpose: New techniques and materials have recently been developed to expedite the conventional Linac Acceptance Testing Procedure (ATP). The new ATP method uses the Electronic Portal Imaging Device (EPID) for data collection and is presented separately. This new procedure is meant to be more efficient then conventional methods. While not clinically implemented yet, a prospective risk assessment is warranted for any new techniques. The purpose of this work is to investigate the risks and establish the pros and cons between the conventional approach and the new ATP method. Methods: ATP tests that were modified and performed with the EPID weremore » analyzed. Five domain experts (Medical Physicists) comprised the core analysis team. Ranking scales were adopted from previous publications related to TG 100. The number of failure pathways for each ATP test procedure were compared as well as the number of risk priority numbers (RPN’s) greater than 100 were compared. Results: There were fewer failure pathways with the new ATP compared to the conventional, 262 and 556, respectively. There were fewer RPN’s > 100 in the new ATP compared to the conventional, 41 and 115. Failure pathways and RPN’s > 100 for individual ATP tests on average were 2 and 3.5 times higher in the conventional ATP compared to the new, respectively. The pixel sensitivity map of the EPID was identified as a key hazard to the new ATP procedure with an RPN of 288 for verifying beam parameters. Conclusion: The significant decrease in failure pathways and RPN’s >100 for the new ATP mitigates the possibilities of a catastrophic error occurring. The Pixel Sensitivity Map determining the response and inherent characteristics of the EPID is crucial as all data and hence results are dependent on that process. Grant from Varian Medical Systems Inc.« less

Influence of bicortical techniques in internal connection placed in premaxillary area by 3D finite element analysis.

PubMed

Verri, Fellippo Ramos; Cruz, Ronaldo Silva; Lemos, Cleidiel Aparecido Araújo; de Souza Batista, Victor Eduardo; Almeida, Daniel Augusto Faria; Verri, Ana Caroline Gonçales; Pellizzer, Eduardo Piza

2017-02-01

The aim of study was to evaluate the stress distribution in implant-supported prostheses and peri-implant bone using internal hexagon (IH) implants in the premaxillary area, varying surgical techniques (conventional, bicortical and bicortical in association with nasal floor elevation), and loading directions (0°, 30° and 60°) by three-dimensional (3D) finite element analysis. Three models were designed with Invesalius, Rhinoceros 3D and Solidworks software. Each model contained a bone block of the premaxillary area including an implant (IH, Ø4 × 10 mm) supporting a metal-ceramic crown. 178 N was applied in different inclinations (0°, 30°, 60°). The results were analyzed by von Mises, maximum principal stress, microstrain and displacement maps including ANOVA statistical test for some situations. Von Mises maps of implant, screws and abutment showed increase of stress concentration as increased loading inclination. Bicortical techniques showed reduction in implant apical area and in the head of fixation screws. Bicortical techniques showed slight increase stress in cortical bone in the maximum principal stress and microstrain maps under 60° loading. No differences in bone tissue regarding surgical techniques were observed. As conclusion, non-axial loads increased stress concentration in all maps. Bicortical techniques showed lower stress for implant and screw; however, there was slightly higher stress on cortical bone only under loads of higher inclinations (60°).

Two-dimensional Shear Wave Elastography on Conventional Ultrasound Scanners with Time Aligned Sequential Tracking (TAST) and Comb-push Ultrasound Shear Elastography (CUSE)

PubMed Central

Song, Pengfei; Macdonald, Michael C.; Behler, Russell H.; Lanning, Justin D.; Wang, Michael H.; Urban, Matthew W.; Manduca, Armando; Zhao, Heng; Callstrom, Matthew R.; Alizad, Azra; Greenleaf, James F.; Chen, Shigao

2014-01-01

Two-dimensional (2D) shear wave elastography presents 2D quantitative shear elasticity maps of tissue, which are clinically useful for both focal lesion detection and diffuse disease diagnosis. Realization of 2D shear wave elastography on conventional ultrasound scanners, however, is challenging due to the low tracking pulse-repetition-frequency (PRF) of these systems. While some clinical and research platforms support software beamforming and plane wave imaging with high PRF, the majority of current clinical ultrasound systems do not have the software beamforming capability, which presents a critical challenge for translating the 2D shear wave elastography technique from laboratory to clinical scanners. To address this challenge, this paper presents a Time Aligned Sequential Tracking (TAST) method for shear wave tracking on conventional ultrasound scanners. TAST takes advantage of the parallel beamforming capability of conventional systems and realizes high PRF shear wave tracking by sequentially firing tracking vectors and aligning shear wave data in the temporal direction. The Comb-push Ultrasound Shear Elastography (CUSE) technique was used to simultaneously produce multiple shear wave sources within the field-of-view (FOV) to enhance shear wave signal-to-noise-ratio (SNR) and facilitate robust reconstructions of 2D elasticity maps. TAST and CUSE were realized on a conventional ultrasound scanner (the General Electric LOGIQ E9). A phantom study showed that the shear wave speed measurements from the LOGIQ E9 were in good agreement to the values measured from other 2D shear wave imaging technologies. An inclusion phantom study showed that the LOGIQ E9 had comparable performance to the Aixplorer (Supersonic Imagine) in terms of bias and precision in measuring different sized inclusions. Finally, in vivo case analysis of a breast with a malignant mass, and a liver from a healthy subject demonstrated the feasibility of using the LOGIQ E9 for in vivo 2D shear wave elastography. These promising results indicate that the proposed technique can enable the implementation of 2D shear wave elastography on conventional ultrasound scanners and potentially facilitate wider clinical applications with shear wave elastography. PMID:25643079

Organic–Inorganic Eu3+/Tb3+ codoped hybrid films for temperature mapping in integrated circuits

PubMed Central

Brites, Carlos D. S.; Lima, Patrícia P.; Silva, Nuno J. O.; Millán, Angel; Amaral, Vitor S.; Palacio, Fernando; Carlos, Luís D.

2013-01-01

The continuous decrease on the geometric size of electronic devices and integrated circuits generates higher local power densities and localized heating problems that cannot be characterized by conventional thermographic techniques. Here, a self-referencing intensity-based molecular thermometer involving a di-ureasil organic-inorganic hybrid thin film co-doped with Eu3+ and Tb3+ tris (β-diketonate) chelates is used to obtain the temperature map of a FR4 printed wiring board with spatio-temporal resolutions of 0.42 μm/4.8 ms. PMID:24790938

Mapping soil features from multispectral scanner data

NASA Technical Reports Server (NTRS)

Kristof, S. J.; Zachary, A. L.

1974-01-01

In being able to identify quickly gross variations in soil features, the computer-aided classification of multispectral scanner data can be an effective aid to soil surveying. Variations in soil tone are easily seen as well as variations in features related to soil tone, e.g., drainage patterns and organic matter content. Changes in surface texture also affect the reflectance properties of soils. Inasmuch as conventional soil classes are based on both surface and subsurface soil characteristics, the technique described here can be expected only to augment and not replace traditional soil mapping.

Comparing the efficiency of digital and conventional soil mapping to predict soil types in a semi-arid region in Iran

NASA Astrophysics Data System (ADS)

Zeraatpisheh, Mojtaba; Ayoubi, Shamsollah; Jafari, Azam; Finke, Peter

2017-05-01

The efficiency of different digital and conventional soil mapping approaches to produce categorical maps of soil types is determined by cost, sample size, accuracy and the selected taxonomic level. The efficiency of digital and conventional soil mapping approaches was examined in the semi-arid region of Borujen, central Iran. This research aimed to (i) compare two digital soil mapping approaches including Multinomial logistic regression and random forest, with the conventional soil mapping approach at four soil taxonomic levels (order, suborder, great group and subgroup levels), (ii) validate the predicted soil maps by the same validation data set to determine the best method for producing the soil maps, and (iii) select the best soil taxonomic level by different approaches at three sample sizes (100, 80, and 60 point observations), in two scenarios with and without a geomorphology map as a spatial covariate. In most predicted maps, using both digital soil mapping approaches, the best results were obtained using the combination of terrain attributes and the geomorphology map, although differences between the scenarios with and without the geomorphology map were not significant. Employing the geomorphology map increased map purity and the Kappa index, and led to a decrease in the 'noisiness' of soil maps. Multinomial logistic regression had better performance at higher taxonomic levels (order and suborder levels); however, random forest showed better performance at lower taxonomic levels (great group and subgroup levels). Multinomial logistic regression was less sensitive than random forest to a decrease in the number of training observations. The conventional soil mapping method produced a map with larger minimum polygon size because of traditional cartographic criteria used to make the geological map 1:100,000 (on which the conventional soil mapping map was largely based). Likewise, conventional soil mapping map had also a larger average polygon size that resulted in a lower level of detail. Multinomial logistic regression at the order level (map purity of 0.80), random forest at the suborder (map purity of 0.72) and great group level (map purity of 0.60), and conventional soil mapping at the subgroup level (map purity of 0.48) produced the most accurate maps in the study area. The multinomial logistic regression method was identified as the most effective approach based on a combined index of map purity, map information content, and map production cost. The combined index also showed that smaller sample size led to a preference for the order level, while a larger sample size led to a preference for the great group level.

Satellite-aided survey sampling and implementation in low- and middle-income contexts: a low-cost/low-tech alternative.

PubMed

Haenssgen, Marco J

2015-01-01

The increasing availability of online maps, satellite imagery, and digital technology can ease common constraints of survey sampling in low- and middle-income countries. However, existing approaches require specialised software and user skills, professional GPS equipment, and/or commercial data sources; they tend to neglect spatial sampling considerations when using satellite maps; and they continue to face implementation challenges analogous to conventional survey implementation methods. This paper presents an alternative way of utilising satellite maps and digital aides that aims to address these challenges. The case studies of two rural household surveys in Rajasthan (India) and Gansu (China) compare conventional survey sampling and implementation techniques with the use of online map services such as Google, Bing, and HERE maps. Modern yet basic digital technology can be integrated into the processes of preparing, implementing, and monitoring a rural household survey. Satellite-aided systematic random sampling enhanced the spatial representativeness of the village samples and entailed savings of approximately £4000 compared to conventional household listing, while reducing the duration of the main survey by at least 25 %. This low-cost/low-tech satellite-aided survey sampling approach can be useful for student researchers and resource-constrained research projects operating in low- and middle-income contexts with high survey implementation costs. While achieving transparent and efficient survey implementation at low costs, researchers aiming to adopt a similar process should be aware of the locational, technical, and logistical requirements as well as the methodological challenges of this strategy.

Diffuse ultrasound monitoring of stress and damage development on a 15-ton concrete beam.

PubMed

Zhang, Yuxiang; Planès, Thomas; Larose, Eric; Obermann, Anne; Rospars, Claude; Moreau, Gautier

2016-04-01

This paper describes the use of an ultrasonic imaging technique (Locadiff) for the Non-Destructive Testing & Evaluation of a concrete structure. By combining coda wave interferometry and a sensitivity kernel for diffuse waves, Locadiff can monitor the elastic and structural properties of a heterogeneous material with a high sensitivity, and can map changes of these properties over time when a perturbation occurs in the bulk of the material. The applicability of the technique to life-size concrete structures is demonstrated through the monitoring of a 15-ton reinforced concrete beam subject to a four-point bending test causing cracking. The experimental results show that Locadiff achieved to (1) detect and locate the cracking zones in the core of the concrete beam at an early stage by mapping the changes in the concrete's micro-structure; (2) monitor the internal stress level in both temporal and spatial domains by mapping the variation in velocity caused by the acousto-elastic effect. The mechanical behavior of the concrete structure is also studied using conventional techniques such as acoustic emission, vibrating wire extensometers, and digital image correlation. The performances of the Locadiff technique in the detection of early stage cracking are assessed and discussed.

Mapping experiment with space station

NASA Technical Reports Server (NTRS)

Wu, S. S. C.

1986-01-01

Mapping of the Earth from space stations can be approached in two areas. One is to collect gravity data for defining topographic datum using Earth's gravity field in terms of spherical harmonics. The other is to search and explore techniques of mapping topography using either optical or radar images with or without reference to ground central points. Without ground control points, an integrated camera system can be designed. With ground control points, the position of the space station (camera station) can be precisely determined at any instant. Therefore, terrestrial topography can be precisely mapped either by conventional photogrammetric methods or by current digital technology of image correlation. For the mapping experiment, it is proposed to establish four ground points either in North America or Africa (including the Sahara desert). If this experiment should be successfully accomplished, it may also be applied to the defense charting systems.

Inversion group (IG) fitting: A new T1 mapping method for modified look-locker inversion recovery (MOLLI) that allows arbitrary inversion groupings and rest periods (including no rest period).

PubMed

Sussman, Marshall S; Yang, Issac Y; Fok, Kai-Ho; Wintersperger, Bernd J

2016-06-01

The Modified Look-Locker Inversion Recovery (MOLLI) technique is used for T1 mapping in the heart. However, a drawback of this technique is that it requires lengthy rest periods in between inversion groupings to allow for complete magnetization recovery. In this work, a new MOLLI fitting algorithm (inversion group [IG] fitting) is presented that allows for arbitrary combinations of inversion groupings and rest periods (including no rest period). Conventional MOLLI algorithms use a three parameter fitting model. In IG fitting, the number of parameters is two plus the number of inversion groupings. This increased number of parameters permits any inversion grouping/rest period combination. Validation was performed through simulation, phantom, and in vivo experiments. IG fitting provided T1 values with less than 1% discrepancy across a range of inversion grouping/rest period combinations. By comparison, conventional three parameter fits exhibited up to 30% discrepancy for some combinations. The one drawback with IG fitting was a loss of precision-approximately 30% worse than the three parameter fits. IG fitting permits arbitrary inversion grouping/rest period combinations (including no rest period). The cost of the algorithm is a loss of precision relative to conventional three parameter fits. Magn Reson Med 75:2332-2340, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

Friction force microscopy: a simple technique for identifying graphene on rough substrates and mapping the orientation of graphene grains on copper

NASA Astrophysics Data System (ADS)

Marsden, A. J.; Phillips, M.; Wilson, N. R.

2013-06-01

At a single atom thick, it is challenging to distinguish graphene from its substrate using conventional techniques. In this paper we show that friction force microscopy (FFM) is a simple and quick technique for identifying graphene on a range of samples, from growth substrates to rough insulators. We show that FFM is particularly effective for characterizing graphene grown on copper where it can correlate the graphene growth to the three-dimensional surface topography. Atomic lattice stick-slip friction is readily resolved and enables the crystallographic orientation of the graphene to be mapped nondestructively, reproducibly and at high resolution. We expect FFM to be similarly effective for studying graphene growth on other metal/locally crystalline substrates, including SiC, and for studying growth of other two-dimensional materials such as molybdenum disulfide and hexagonal boron nitride.

Applied photo interpretation for airbrush cartography

NASA Technical Reports Server (NTRS)

Inge, J. L.; Bridges, P. M.

1976-01-01

Lunar and planetary exploration has required the development of new techniques of cartographic portrayal. Conventional photo-interpretive methods employing size, shape, shadow, tone, pattern, and texture are applied to computer-processed satellite television images. Comparative judgements are affected by illumination, resolution, variations in surface coloration, and transmission or processing artifacts. The portrayal of tonal densities in a relief illustration is performed using a unique airbrush technique derived from hill-shading of contour maps. The control of tone and line quality is essential because the mid-gray to dark tone densities must be finalized prior to the addition of highlights to the drawing. This is done with an electric eraser until the drawing is completed. The drawing density is controlled with a reflectance-reading densitometer to meet certain density guidelines. The versatility of planetary photo-interpretive methods for airbrushed map portrayals is demonstrated by the application of these techniques to the synthesis of nonrelief data.

USGS Map-on-Demand Printing

USGS Publications Warehouse

,

1999-01-01

Currently, the U.S. Geological Survey (USGS) uses conventional lithographic printing techniques to produce paper copies of most of its mapping products. This practice is not economical for those products that are in low demand. With the advent of newer technologies, high-speed, large-format printers have been coupled with innovative computer software to turn digital map data into a printed map. It is now possible to store and retrieve data from vast geospatial data bases and print a map on an as-needed basis; that is, print on demand, thereby eliminating the need to warehouse an inventory of paper maps for which there is low demand. Using print-on-demand technology, the USGS is implementing map-on-demand (MOD) printing for certain infrequently requested maps. By providing MOD, the USGS can offer an alternative to traditional, large-volume printing and can improve its responsiveness to customers by giving them greater access to USGS scientific data in a format that otherwise might not be available.

Rationale and design of the NO-PARTY trial: near-zero fluoroscopic exposure during catheter ablation of supraventricular arrhythmias in young patients.

PubMed

Casella, Michela; Dello Russo, Antonio; Pelargonio, Gemma; Bongiorni, Maria Grazia; Del Greco, Maurizio; Piacenti, Marcello; Andreassi, Maria Grazia; Santangeli, Pasquale; Bartoletti, Stefano; Moltrasio, Massimo; Fassini, Gaetano; Marini, Massimiliano; Di Cori, Andrea; Di Biase, Luigi; Fiorentini, Cesare; Zecchi, Paolo; Natale, Andrea; Picano, Eugenio; Tondo, Claudio

2012-10-01

Radiofrequency catheter ablation is the mainstay of therapy for supraventricular tachyarrhythmias. Conventional radiofrequency catheter ablation requires the use of fluoroscopy, thus exposing patients to ionising radiation. The feasibility and safety of non-fluoroscopic radiofrequency catheter ablation has been recently reported in a wide range of supraventricular tachyarrhythmias using the EnSite NavX™ mapping system. The NO-PARTY is a multi-centre, randomised controlled trial designed to test the hypothesis that catheter ablation of supraventricular tachyarrhythmias guided by the EnSite NavX™ mapping system results in a clinically significant reduction in exposure to ionising radiation compared with conventional catheter ablation. The study will randomise 210 patients undergoing catheter ablation of supraventricular tachyarrhythmias to either a conventional ablation technique or one guided by the EnSite NavX™ mapping system. The primary end-point is the reduction of the radiation dose to the patient. Secondary end-points include procedural success, reduction of the radiation dose to the operator, and a cost-effectiveness analysis. In a subgroup of patients, we will also evaluate the radiobiological effectiveness of dose reduction by assessing acute chromosomal DNA damage in peripheral blood lymphocytes. NO-PARTY will determine whether radiofrequency catheter ablation of supraventricular tachyarrhythmias guided by the EnSite NavX™ mapping system is a suitable and cost-effective approach to achieve a clinically significant reduction in ionising radiation exposure for both patient and operator.

Characterization of Electronic Materials HgZnSe and HgZnTe Using Innovative and Conventional Techniques

NASA Technical Reports Server (NTRS)

Tanton, George; Kesmodel, Roy; Burden, Judy; Su, Ching-Hua; Cobb, Sharon D.; Lehoczky, S. L.

2000-01-01

HgZnSe and HgZnTe are electronic materials of interest for potential IR detector and focal plane array applications due to their improved strength and compositional stability over HgCdTe, but they are difficult to grow on Earth and to fully characterize. Conventional contact methods of characterization, such as Hall and van der Paw, although adequate for many situations are typically labor intensive and not entirely suitable where only very small samples are available. To adequately characterize and compare properties of electronic materials grown in low earth orbit with those grown on Earth, innovative techniques are needed that complement existing methods. This paper describes the implementation and test results of a unique non-contact method of characterizing uniformity, mobility, and carrier concentration together with results from conventional methods applied to HgZnSe and HgZnTe. The innovative method has advantages over conventional contact methods since it circumvents problems of possible contamination from alloying electrical contacts to a sample and also has the capability to map a sample. Non- destructive mapping, the determination of the carrier concentration and mobility at each place on a sample, provides a means to quantitatively compare, at high spatial resolution, effects of microgravity on electronic properties and uniformity of electronic materials grown in low-Earth orbit with Earth grown materials. The mapping technique described here uses a 1mm diameter polarized beam of radiation to probe the sample. Activation of a magnetic field, in which the sample is placed, causes the plane of polarization of the probe beam to rotate. This Faraday rotation is a function of the free carrier concentration and the band parameters of the material. Maps of carrier concentration, mobility, and transmission generated from measurements of the Faraday rotation angles over the temperature range from 300K to 77K will be presented. New information on band parameters, obtained by combining results from conventional Hall measurements of the free carrier concentration with Faraday rotation measurements, will also be presented. One example of how this type of information was derived is illustrated in the following figure which shows Faraday rotation vs wavelength modeled for Hg(l-x)ZnxSe at a temperature of 300K and x=0.07. The plasma contribution, total Faraday rotation, and interband contribution to the Faraday rotation, are designated in the Figure as del(p), FR tot, and del(i) respectively. Experimentally measured values of FR tot, each indicated by + , agree acceptably well with the model at the probe wavelength of 10.6 microns. The model shows that at the probe wavelength, practically all the rotation is due to the plasma component, which can be expressed as delta(sub p)= 2pi(e(sup 3))NBL/c(sup 2)nm*(sup 2) omega(sup 2). In this equation, delta(sub p) is the rotation angle due to the free carrier plasma, N is the free carrier concentration, B the magnetic field strength, L the thickness of the sample, n the index of refraction, omega the probe radiation frequency, c the speed of light, e the electron charge, and m* the effective mass. A measurement of N by conventional techniques, combined with a measurement of the Faraday rotation angle allows m* to be accurately determined since it is an inverse square function.

Specifications for updating USGS land use and land cover maps

USGS Publications Warehouse

Milazzo, Valerie A.

1983-01-01

To meet the increasing demands for up-to-date land use and land cover information, a primary goal of the U.S. Geological Survey's (USGS) national land use and land cover mapping program is to provide for periodic updating of maps and data in a timely and uniform manner. The technical specifications for updating existing USGS land use and land cover maps that are presented here cover both the interpretive aspects of detecting and identifying land use and land cover changes and the cartographic aspects of mapping and presenting the change data in conventional map format. They provide the map compiler with the procedures and techniques necessary to then use these change data to update existing land use and land cover maps in a manner that is both standardized and repeatable. Included are specifications for the acquisition of remotely sensed source materials, selection of compilation map bases, handling of data base corrections, editing and quality control operations, generation of map update products for USGS open file, and the reproduction and distribution of open file materials. These specifications are planned to become part of the National Mapping Division's Technical Instructions.

Parallel mapping of optical near-field interactions by molecular motor-driven quantum dots.

PubMed

Groß, Heiko; Heil, Hannah S; Ehrig, Jens; Schwarz, Friedrich W; Hecht, Bert; Diez, Stefan

2018-04-30

In the vicinity of metallic nanostructures, absorption and emission rates of optical emitters can be modulated by several orders of magnitude 1,2 . Control of such near-field light-matter interaction is essential for applications in biosensing 3 , light harvesting 4 and quantum communication 5,6 and requires precise mapping of optical near-field interactions, for which single-emitter probes are promising candidates 7-11 . However, currently available techniques are limited in terms of throughput, resolution and/or non-invasiveness. Here, we present an approach for the parallel mapping of optical near-field interactions with a resolution of <5 nm using surface-bound motor proteins to transport microtubules carrying single emitters (quantum dots). The deterministic motion of the quantum dots allows for the interpolation of their tracked positions, resulting in an increased spatial resolution and a suppression of localization artefacts. We apply this method to map the near-field distribution of nanoslits engraved into gold layers and find an excellent agreement with finite-difference time-domain simulations. Our technique can be readily applied to a variety of surfaces for scalable, nanometre-resolved and artefact-free near-field mapping using conventional wide-field microscopes.

Improved 3D seismic attribute mapping by CRS stacking instead of NMO stacking: Application to a geothermal reservoir in the Polish Basin

NASA Astrophysics Data System (ADS)

Pussak, Marcin; Bauer, Klaus; Stiller, Manfred; Bujakowski, Wieslaw

2014-04-01

Within a seismic reflection processing work flow, the common-reflection-surface (CRS) stack can be applied as an alternative for the conventional normal moveout (NMO) or the dip moveout (DMO) stack. The advantages of the CRS stack include (1) data-driven automatic determination of stacking operator parameters, (2) imaging of arbitrarily curved geological boundaries, and (3) significant increase in signal-to-noise (S/N) ratio by stacking far more traces than used in a conventional stack. In this paper we applied both NMO and CRS stackings to process a sparse 3D seismic data set acquired within a geothermal exploration study in the Polish Basin. The stacked images show clear enhancements in quality achieved by the CRS stack in comparison with the conventional stack. While this was expected from previous studies, we also found remarkable improvements in the quality of seismic attributes when the CRS stack was applied instead of the conventional stack. For the major geothermal target reservoir (Lower Jurassic horizon Ja1), we present a comparison between both stacking methods for a number of common attributes, including root-mean-square (RMS) amplitudes, instantaneous frequencies, coherency, and spectral decomposition attributes derived from the continuous wavelet transform. The attribute maps appear noisy and highly fluctuating after the conventional stack, and are clearly structured after the CRS stack. A seismic facies analysis was finally carried out for the Ja1 horizon using the attributes derived from the CRS stack by using self-organizing map clustering techniques. A corridor parallel to a fault system was identified, which is characterized by decreased RMS amplitudes and decreased instantaneous frequencies. In our interpretation, this region represents a fractured, fluid-bearing compartment within the sandstone reservoir, which indicates favorable conditions for geothermal exploitation.

Multielement mapping of alpha-SiC by scanning Auger microscopy

NASA Technical Reports Server (NTRS)

Browning, Ray; Smialek, James L.; Jacobson, Nathan S.

1987-01-01

Fine second-phase particles, numerous in sintered alpha-SiC, were analyzed by scanning Auger microscopy and conventional techniques. The Auger analysis utilized computer-controlled data acquisition, multielement correlation diagrams, and a high spatial resolution of 100 nm. This procedure enabled construction of false color maps and the detection of fine compositional details within these particles. Carbon, silicon oxide, and boron-rich particles (qualitatively as BN or B4C) predominated. The BN particles, sometimes having a carbon core, are believed to result from reaction between B4C additives and nitrogen sintering atmospheres.

Usage of multivariate geostatistics in interpolation processes for meteorological precipitation maps

NASA Astrophysics Data System (ADS)

Gundogdu, Ismail Bulent

2017-01-01

Long-term meteorological data are very important both for the evaluation of meteorological events and for the analysis of their effects on the environment. Prediction maps which are constructed by different interpolation techniques often provide explanatory information. Conventional techniques, such as surface spline fitting, global and local polynomial models, and inverse distance weighting may not be adequate. Multivariate geostatistical methods can be more significant, especially when studying secondary variables, because secondary variables might directly affect the precision of prediction. In this study, the mean annual and mean monthly precipitations from 1984 to 2014 for 268 meteorological stations in Turkey have been used to construct country-wide maps. Besides linear regression, the inverse square distance and ordinary co-Kriging (OCK) have been used and compared to each other. Also elevation, slope, and aspect data for each station have been taken into account as secondary variables, whose use has reduced errors by up to a factor of three. OCK gave the smallest errors (1.002 cm) when aspect was included.

Satellite SAR interferometric techniques applied to emergency mapping

NASA Astrophysics Data System (ADS)

Stefanova Vassileva, Magdalena; Riccardi, Paolo; Lecci, Daniele; Giulio Tonolo, Fabio; Boccardo Boccardo, Piero; Chiesa, Giuliana; Angeluccetti, Irene

2017-04-01

This paper aim to investigate the capabilities of the currently available SAR interferometric algorithms in the field of emergency mapping. Several tests have been performed exploiting the Copernicus Sentinel-1 data using the COTS software ENVI/SARscape 5.3. Emergency Mapping can be defined as "creation of maps, geo-information products and spatial analyses dedicated to providing situational awareness emergency management and immediate crisis information for response by means of extraction of reference (pre-event) and crisis (post-event) geographic information/data from satellite or aerial imagery". The conventional differential SAR interferometric technique (DInSAR) and the two currently available multi-temporal SAR interferometric approaches, i.e. Permanent Scatterer Interferometry (PSI) and Small BAseline Subset (SBAS), have been applied to provide crisis information useful for the emergency management activities. Depending on the considered Emergency Management phase, it may be distinguished between rapid mapping, i.e. fast provision of geospatial data regarding the area affected for the immediate emergency response, and monitoring mapping, i.e. detection of phenomena for risk prevention and mitigation activities. In order to evaluate the potential and limitations of the aforementioned SAR interferometric approaches for the specific rapid and monitoring mapping application, five main factors have been taken into account: crisis information extracted, input data required, processing time and expected accuracy. The results highlight that DInSAR has the capacity to delineate areas affected by large and sudden deformations and fulfills most of the immediate response requirements. The main limiting factor of interferometry is the availability of suitable SAR acquisition immediately after the event (e.g. Sentinel-1 mission characterized by 6-day revisiting time may not always satisfy the immediate emergency request). PSI and SBAS techniques are suitable to produce monitoring maps for risk prevention and mitigation purposes. Nevertheless, multi-temporal techniques require large SAR temporal datasets, i.e. 20 and more images. Being the Sentinel-1 missions operational only since April 2014, multi-mission SAR datasets should be therefore exploited to carry out historical analysis.

A Background Noise Reduction Technique Using Adaptive Noise Cancellation for Microphone Arrays

NASA Technical Reports Server (NTRS)

Spalt, Taylor B.; Fuller, Christopher R.; Brooks, Thomas F.; Humphreys, William M., Jr.; Brooks, Thomas F.

2011-01-01

Background noise in wind tunnel environments poses a challenge to acoustic measurements due to possible low or negative Signal to Noise Ratios (SNRs) present in the testing environment. This paper overviews the application of time domain Adaptive Noise Cancellation (ANC) to microphone array signals with an intended application of background noise reduction in wind tunnels. An experiment was conducted to simulate background noise from a wind tunnel circuit measured by an out-of-flow microphone array in the tunnel test section. A reference microphone was used to acquire a background noise signal which interfered with the desired primary noise source signal at the array. The technique s efficacy was investigated using frequency spectra from the array microphones, array beamforming of the point source region, and subsequent deconvolution using the Deconvolution Approach for the Mapping of Acoustic Sources (DAMAS) algorithm. Comparisons were made with the conventional techniques for improving SNR of spectral and Cross-Spectral Matrix subtraction. The method was seen to recover the primary signal level in SNRs as low as -29 dB and outperform the conventional methods. A second processing approach using the center array microphone as the noise reference was investigated for more general applicability of the ANC technique. It outperformed the conventional methods at the -29 dB SNR but yielded less accurate results when coherence over the array dropped. This approach could possibly improve conventional testing methodology but must be investigated further under more realistic testing conditions.

Microearthquake Studies at the Salton Sea Geothermal Field

DOE Data Explorer

Templeton, Dennise

2013-10-01

The objective of this project is to detect and locate microearthquakes to aid in the characterization of reservoir fracture networks. Accurate identification and mapping of the large numbers of microearthquakes induced in EGS is one technique that provides diagnostic information when determining the location, orientation and length of underground crack systems for use in reservoir development and management applications. Conventional earthquake location techniques often are employed to locate microearthquakes. However, these techniques require labor-intensive picking of individual seismic phase onsets across a network of sensors. For this project we adapt the Matched Field Processing (MFP) technique to the elastic propagation problem in geothermal reservoirs to identify more and smaller events than traditional methods alone.

Imaging of conductivity distributions using audio-frequency electromagnetic data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Ki Ha; Morrison, H.F.

1990-10-01

The objective of this study has been to develop mathematical methods for mapping conductivity distributions between boreholes using low frequency electromagnetic (em) data. In relation to this objective this paper presents two recent developments in high-resolution crosshole em imaging techniques. These are (1) audio-frequency diffusion tomography, and (2) a transform method in which low frequency data is first transformed into a wave-like field. The idea in the second approach is that we can then treat the transformed field using conventional techniques designed for wave field analysis.

Pressure-Sensitive Paint Measurements on Surfaces with Non-Uniform Temperature

NASA Technical Reports Server (NTRS)

Bencic, Timothy J.

1999-01-01

Pressure-sensitive paint (PSP) has become a useful tool to augment conventional pressure taps in measuring the surface pressure distribution of aerodynamic components in wind tunnel testing. While the PSP offers the advantage of a non-intrusive global mapping of the surface pressure, one prominent drawback to the accuracy of this technique is the inherent temperature sensitivity of the coating's luminescent intensity. A typical aerodynamic surface PSP test has relied on the coated surface to be both spatially and temporally isothermal, along with conventional instrumentation for an in situ calibration to generate the highest accuracy pressure mappings. In some tests however, spatial and temporal thermal gradients are generated by the nature of the test as in a blowing jet impinging on a surface. In these cases, the temperature variations on the painted surface must be accounted for in order to yield high accuracy and reliable data. A new temperature correction technique was developed at NASA Lewis to collapse a "family" of PSP calibration curves to a single intensity ratio versus pressure curve. This correction allows a streamlined procedure to be followed whether or not temperature information is used in the data reduction of the PSP. This paper explores the use of conventional instrumentation such as thermocouples and pressure taps along with temperature-sensitive paint (TSP) to correct for the thermal gradients that exist in aeropropulsion PSP tests. Temperature corrected PSP measurements for both a supersonic mixer ejector and jet cavity interaction tests are presented.

Patch-Based Super-Resolution of MR Spectroscopic Images: Application to Multiple Sclerosis

PubMed Central

Jain, Saurabh; Sima, Diana M.; Sanaei Nezhad, Faezeh; Hangel, Gilbert; Bogner, Wolfgang; Williams, Stephen; Van Huffel, Sabine; Maes, Frederik; Smeets, Dirk

2017-01-01

Purpose: Magnetic resonance spectroscopic imaging (MRSI) provides complementary information to conventional magnetic resonance imaging. Acquiring high resolution MRSI is time consuming and requires complex reconstruction techniques. Methods: In this paper, a patch-based super-resolution method is presented to increase the spatial resolution of metabolite maps computed from MRSI. The proposed method uses high resolution anatomical MR images (T1-weighted and Fluid-attenuated inversion recovery) to regularize the super-resolution process. The accuracy of the method is validated against conventional interpolation techniques using a phantom, as well as simulated and in vivo acquired human brain images of multiple sclerosis subjects. Results: The method preserves tissue contrast and structural information, and matches well with the trend of acquired high resolution MRSI. Conclusions: These results suggest that the method has potential for clinically relevant neuroimaging applications. PMID:28197066

On the derivation of coseismic displacement fields using differential radar interferometry: The Landers earthquake

NASA Technical Reports Server (NTRS)

Zebker, Howard A.; Rosen, Paul A.; Goldstein, Richard M.; Gabriel, Andrew; Werner, Charles L.

1994-01-01

We present a map of the coseimic displacement field resulting from the Landers, California, June 28, 1992, earthquake derived using data acquired from an orbiting high-resolution radar system. We achieve results more accurate than previous space studies and similar in accuracy to those obtained by conventional field survey techniques. Data from the ERS 1 synthetic aperture radar instrument acquired in April, July, and August 1992 are used to generate a high-resolution, wide area map of the displacements. The data represent the motion in the direction of the radar line of sight to centimeter level precision of each 30-m resolution element in a 113 km by 90 km image. Our coseismic displacement contour map gives a lobed pattern consistent with theoretical models of the displacement field from the earthquake. Fine structure observed as displacement tiling in regions several kilometers from the fault appears to be the result of local surface fracturing. Comparison of these data with Global Positioning System and electronic distance measurement survey data yield a correlation of 0.96; thus the radar measurements are a means to extend the point measurements acquired by traditional techniques to an area map format. The technique we use is (1) more automatic, (2) more precise, and (3) better validated than previous similar applications of differential radar interferometry. Since we require only remotely sensed satellite data with no additioanl requirements for ancillary information. the technique is well suited for global seismic monitoring and analysis.

Mapping in vitro local material properties of intact and disrupted virions at high resolution using multi-harmonic atomic force microscopy.

PubMed

Cartagena, Alexander; Hernando-Pérez, Mercedes; Carrascosa, José L; de Pablo, Pedro J; Raman, Arvind

2013-06-07

Understanding the relationships between viral material properties (stiffness, strength, charge density, adhesion, hydration, viscosity, etc.), structure (protein sub-units, genome, surface receptors, appendages), and functions (self-assembly, stability, disassembly, infection) is of significant importance in physical virology and nanomedicine. Conventional Atomic Force Microscopy (AFM) methods have measured a single physical property such as the stiffness of the entire virus from nano-indentation at a few points which severely limits the study of structure-property-function relationships. We present an in vitro dynamic AFM technique operating in the intermittent contact regime which synthesizes anharmonic Lorentz-force excited AFM cantilevers to map quantitatively at nanometer resolution the local electro-mechanical force gradient, adhesion, and hydration layer viscosity within individual φ29 virions. Furthermore, the changes in material properties over the entire φ29 virion provoked by the local disruption of its shell are studied, providing evidence of bacteriophage depressurization. The technique significantly generalizes recent multi-harmonic theory (A. Raman, et al., Nat. Nanotechnol., 2011, 6, 809-814) and enables high-resolution in vitro quantitative mapping of multiple material properties within weakly bonded viruses and nanoparticles with complex structure that otherwise cannot be observed using standard AFM techniques.

Language mapping in children using resting-state functional connectivity: comparison with a task-based approach

NASA Astrophysics Data System (ADS)

Gallagher, Anne; Tremblay, Julie; Vannasing, Phetsamone

2016-12-01

Patients with brain tumor or refractory epilepsy may be candidates for neurosurgery. Presurgical evaluation often includes language investigation to prevent or reduce the risk of postsurgical language deficits. Current techniques involve significant limitations with pediatric populations. Recently, near-infrared spectroscopy (NIRS) has been shown to be a valuable neuroimaging technique for language localization in children. However, it typically requires the child to perform a task (task-based NIRS), which may constitute a significant limitation. Resting-state functional connectivity NIRS (fcNIRS) is an approach that can be used to identify language networks at rest. This study aims to assess the utility of fcNIRS in children by comparing fcNIRS to more conventional task-based NIRS for language mapping in 33 healthy participants: 25 children (ages 3 to 16) and 8 adults. Data were acquired at rest and during a language task. Results show very good concordance between both approaches for language localization (Dice similarity coefficient=0.81±0.13) and hemispheric language dominance (kappa=0.86, p<0.006). The fcNIRS technique may be a valuable tool for language mapping in clinical populations, including children and patients with cognitive and behavioral impairments.

HiC-spector: a matrix library for spectral and reproducibility analysis of Hi-C contact maps.

PubMed

Yan, Koon-Kiu; Yardimci, Galip Gürkan; Yan, Chengfei; Noble, William S; Gerstein, Mark

2017-07-15

Genome-wide proximity ligation based assays like Hi-C have opened a window to the 3D organization of the genome. In so doing, they present data structures that are different from conventional 1D signal tracks. To exploit the 2D nature of Hi-C contact maps, matrix techniques like spectral analysis are particularly useful. Here, we present HiC-spector, a collection of matrix-related functions for analyzing Hi-C contact maps. In particular, we introduce a novel reproducibility metric for quantifying the similarity between contact maps based on spectral decomposition. The metric successfully separates contact maps mapped from Hi-C data coming from biological replicates, pseudo-replicates and different cell types. Source code in Julia and Python, and detailed documentation is available at https://github.com/gersteinlab/HiC-spector . koonkiu.yan@gmail.com or mark@gersteinlab.org. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

Seismic hazard assessment of Syria using seismicity, DEM, slope, active tectonic and GIS

NASA Astrophysics Data System (ADS)

Ahmad, Raed; Adris, Ahmad; Singh, Ramesh

2016-07-01

In the present work, we discuss the use of an integrated remote sensing and Geographical Information System (GIS) techniques for evaluation of seismic hazard areas in Syria. The present study is the first time effort to create seismic hazard map with the help of GIS. In the proposed approach, we have used Aster satellite data, digital elevation data (30 m resolution), earthquake data, and active tectonic maps. Many important factors for evaluation of seismic hazard were identified and corresponding thematic data layers (past earthquake epicenters, active faults, digital elevation model, and slope) were generated. A numerical rating scheme has been developed for spatial data analysis using GIS to identify ranking of parameters to be included in the evaluation of seismic hazard. The resulting earthquake potential map delineates the area into different relative susceptibility classes: high, moderate, low and very low. The potential earthquake map was validated by correlating the obtained different classes with the local probability that produced using conventional analysis of observed earthquakes. Using earthquake data of Syria and the peak ground acceleration (PGA) data is introduced to the model to develop final seismic hazard map based on Gutenberg-Richter (a and b values) parameters and using the concepts of local probability and recurrence time. The application of the proposed technique in Syrian region indicates that this method provides good estimate of seismic hazard map compared to those developed from traditional techniques (Deterministic (DSHA) and probabilistic seismic hazard (PSHA). For the first time we have used numerous parameters using remote sensing and GIS in preparation of seismic hazard map which is found to be very realistic.

76 FR 7810 - Notice of Proposed Change to Section I of the South Dakota and North Dakota State Technical Guides

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-11

... must be made to the NRCS State Technical Guides concerning State wetland mapping conventions. The two States are proposing to issue joint State wetland mapping conventions. The joint State wetland mapping conventions will be used as part of the technical documents to conduct wetland determinations on agriculture...

Evaluation of MRI sequences for quantitative T1 brain mapping

NASA Astrophysics Data System (ADS)

Tsialios, P.; Thrippleton, M.; Glatz, A.; Pernet, C.

2017-11-01

T1 mapping constitutes a quantitative MRI technique finding significant application in brain imaging. It allows evaluation of contrast uptake, blood perfusion, volume, providing a more specific biomarker of disease progression compared to conventional T1-weighted images. While there are many techniques for T1-mapping there is a wide range of reported T1-values in tissues, raising the issue of protocols reproducibility and standardization. The gold standard for obtaining T1-maps is based on acquiring IR-SE sequence. Widely used alternative sequences are IR-SE-EPI, VFA (DESPOT), DESPOT-HIFI and MP2RAGE that speed up scanning and fitting procedures. A custom MRI phantom was used to assess the reproducibility and accuracy of the different methods. All scans were performed using a 3T Siemens Prisma scanner. The acquired data processed using two different codes. The main difference was observed for VFA (DESPOT) which grossly overestimated T1 relaxation time by 214 ms [126 270] compared to the IR-SE sequence. MP2RAGE and DESPOT-HIFI sequences gave slightly shorter time than IR-SE (~20 to 30ms) and can be considered as alternative and time-efficient methods for acquiring accurate T1 maps of the human brain, while IR-SE-EPI gave identical result, at a cost of a lower image quality.

On the design of wave digital filters with low sensitivity properties.

NASA Technical Reports Server (NTRS)

Renner, K.; Gupta, S. C.

1973-01-01

The wave digital filter patterned after doubly terminated maximum available power (MAP) networks by means of the Richard's transformation has been shown to have low-coefficient-sensitivity properties. This paper examines the exact nature of the relationship between the wave-digital-filter structure and the MAP networks and how the sensitivity property arises, which permits implementation of the digital structure with a lower coefficient word length than that possible with the conventional structures. The proper design procedure is specified and the nature of the unique complementary outputs is discussed. Finally, an example is considered which illustrates the design, the conversion techniques, and the low sensitivity properties.

The Use of AIS Data for Identifying and Mapping Calcareous Soils in Western Nebraska

NASA Technical Reports Server (NTRS)

Samson, S. A.

1985-01-01

The identification of calcareous soils, through unique spectral responses of the vegetation to the chemical nature of calcareous soils, can improve the accuracy of delineating the boundaries of soil mapping units over conventional field techniques. The objective of this experiment is to evaluate the use of the Airborne Imaging Spectrometer (AIS) in the identification and delineation of calcareous soils in the western Sandhills of Nebraska. Based upon statistical differences found in separating the spectral curves below 1.3 microns, calcareous and non-calcareous soils may be identified by differences in species of vegetation. Additional work is needed to identify biogeochemical differences between the two soils.

Optogenetic mapping of brain circuitry

NASA Astrophysics Data System (ADS)

Augustine, George J.; Berglund, Ken; Gill, Harin; Hoffmann, Carolin; Katarya, Malvika; Kim, Jinsook; Kudolo, John; Lee, Li M.; Lee, Molly; Lo, Daniel; Nakajima, Ryuichi; Park, Min Yoon; Tan, Gregory; Tang, Yanxia; Teo, Peggy; Tsuda, Sachiko; Wen, Lei; Yoon, Su-In

2012-10-01

Studies of the brain promise to be revolutionized by new experimental strategies that harness the combined power of optical techniques and genetics. We have mapped the circuitry of the mouse brain by using both optogenetic actuators that control neuronal activity and optogenetic sensors that detect neuronal activity. Using the light-activated cation channel, channelrhodopsin-2, to locally photostimulate neurons allows high-speed mapping of local and long-range circuitry. For example, with this approach we have mapped local circuits in the cerebral cortex, cerebellum and many other brain regions. Using the fluorescent sensor for chloride ions, Clomeleon, allows imaging of the spatial and temporal dimensions of inhibitory circuits in the brain. This approach allows imaging of both conventional "phasic" synaptic inhibition as well as unconventional "tonic" inhibition. The combined use of light to both control and monitor neural activity creates unprecedented opportunities to explore brain function, screen pharmaceutical agents, and potentially to use light to ameliorate psychiatric and neurological disorders.

Self-organizing neural networks--an alternative way of cluster analysis in clinical chemistry.

PubMed

Reibnegger, G; Wachter, H

1996-04-15

Supervised learning schemes have been employed by several workers for training neural networks designed to solve clinical problems. We demonstrate that unsupervised techniques can also produce interesting and meaningful results. Using a data set on the chemical composition of milk from 22 different mammals, we demonstrate that self-organizing feature maps (Kohonen networks) as well as a modified version of error backpropagation technique yield results mimicking conventional cluster analysis. Both techniques are able to project a potentially multi-dimensional input vector onto a two-dimensional space whereby neighborhood relationships remain conserved. Thus, these techniques can be used for reducing dimensionality of complicated data sets and for enhancing comprehensibility of features hidden in the data matrix.

Landslide inventory maps: New tools for an old problem

NASA Astrophysics Data System (ADS)

Guzzetti, Fausto; Mondini, Alessandro Cesare; Cardinali, Mauro; Fiorucci, Federica; Santangelo, Michele; Chang, Kang-Tsung

2012-04-01

Landslides are present in all continents, and play an important role in the evolution of landscapes. They also represent a serious hazard in many areas of the world. Despite their importance, we estimate that landslide maps cover less than 1% of the slopes in the landmasses, and systematic information on the type, abundance, and distribution of landslides is lacking. Preparing landslide maps is important to document the extent of landslide phenomena in a region, to investigate the distribution, types, pattern, recurrence and statistics of slope failures, to determine landslide susceptibility, hazard, vulnerability and risk, and to study the evolution of landscapes dominated by mass-wasting processes. Conventional methods for the production of landslide maps rely chiefly on the visual interpretation of stereoscopic aerial photography, aided by field surveys. These methods are time consuming and resource intensive. New and emerging techniques based on satellite, airborne, and terrestrial remote sensing technologies, promise to facilitate the production of landslide maps, reducing the time and resources required for their compilation and systematic update. In this work, we first outline the principles for landslide mapping, and we review the conventional methods for the preparation of landslide maps, including geomorphological, event, seasonal, and multi-temporal inventories. Next, we examine recent and new technologies for landslide mapping, considering (i) the exploitation of very-high resolution digital elevation models to analyze surface morphology, (ii) the visual interpretation and semi-automatic analysis of different types of satellite images, including panchromatic, multispectral, and synthetic aperture radar images, and (iii) tools that facilitate landslide field mapping. Next, we discuss the advantages and the limitations of the new remote sensing data and technology for the production of geomorphological, event, seasonal, and multi-temporal inventory maps. We conclude by arguing that the new tools will help to improve the quality of landslide maps, with positive effects on all derivative products and analyses, including erosion studies and landscape modeling, susceptibility and hazard assessments, and risk evaluations.

Evaluation of hot forming effects mapping for CAE analyses

NASA Astrophysics Data System (ADS)

Knoerr, L.; Faath, T.; Dykeman, J.; Malcolm, S.

2016-08-01

Hot forming has grown significantly in the manufacturing of structural components within the vehicle Body-In-White construction. The superior strength of press hardened steels not only guarantee high resistance to deformation, it also brings a significant weight saving compared to conventional cold formed products. However, the benefit of achieving ultrahigh strength with hot stamping, comes with a reduction in ductility of the press hardened part. This will require advanced material modeling to capture the predicted performances accurately. A technique to optically measure and map the thinning distribution after hot stamping has shown to improve numerical analysis for fracture prediction. The proposed method to determine the forming effects and mapping to CAE models can be integrated into the Vehicle Development Process to shorten the time to production.

Simulating and mapping spatial complexity using multi-scale techniques

USGS Publications Warehouse

De Cola, L.

1994-01-01

A central problem in spatial analysis is the mapping of data for complex spatial fields using relatively simple data structures, such as those of a conventional GIS. This complexity can be measured using such indices as multi-scale variance, which reflects spatial autocorrelation, and multi-fractal dimension, which characterizes the values of fields. These indices are computed for three spatial processes: Gaussian noise, a simple mathematical function, and data for a random walk. Fractal analysis is then used to produce a vegetation map of the central region of California based on a satellite image. This analysis suggests that real world data lie on a continuum between the simple and the random, and that a major GIS challenge is the scientific representation and understanding of rapidly changing multi-scale fields. -Author

EXPERIMENTS IN LITHOGRAPHY FROM REMOTE SENSOR IMAGERY.

USGS Publications Warehouse

Kidwell, R. H.; McSweeney, J.; Warren, A.; Zang, E.; Vickers, E.

1983-01-01

Imagery from remote sensing systems such as the Landsat multispectral scanner and return beam vidicon, as well as synthetic aperture radar and conventional optical camera systems, contains information at resolutions far in excess of that which can be reproduced by the lithographic printing process. The data often require special handling to produce both standard and special map products. Some conclusions have been drawn regarding processing techniques, procedures for production, and printing limitations.

ATOMIC RESOLUTION CRYO ELECTRON MICROSCOPY OF MACROMOLECULAR COMPLEXES

PubMed Central

ZHOU, Z. HONG

2013-01-01

Single-particle cryo electron microscopy (cryoEM) is a technique for determining three-dimensional (3D) structures from projection images of molecular complexes preserved in their “native,” noncrystalline state. Recently, atomic or near-atomic resolution structures of several viruses and protein assemblies have been determined by single-particle cryoEM, allowing ab initio atomic model building by following the amino acid side chains or nucleic acid bases identifiable in their cryoEM density maps. In particular, these cryoEM structures have revealed extended arms contributing to molecular interactions that are otherwise not resolved by the conventional structural method of X-ray crystallography at similar resolutions. High-resolution cryoEM requires careful consideration of a number of factors, including proper sample preparation to ensure structural homogeneity, optimal configuration of electron imaging conditions to record high-resolution cryoEM images, accurate determination of image parameters to correct image distortions, efficient refinement and computation to reconstruct a 3D density map, and finally appropriate choice of modeling tools to construct atomic models for functional interpretation. This progress illustrates the power of cryoEM and ushers it into the arsenal of structural biology, alongside conventional techniques of X-ray crystallography and NMR, as a major tool (and sometimes the preferred one) for the studies of molecular interactions in supramolecular assemblies or machines. PMID:21501817

The use of various X-ray fluorescence analysis modalities for the investigation of historical paintings: The case study on the Late Gothic panel painting

NASA Astrophysics Data System (ADS)

Bártová, H.; Trojek, T.; Čechák, T.; Šefců, R.; Chlumská, Š.

2017-10-01

The presence of heavy chemical elements in old pigments is possible to identify in historical paintings using X-ray fluorescence analysis (XRF). This is a non-destructive analytical method frequently used in examination of objects that require in situ analysis, where it is necessary to avoid damaging the object by taking samples. Different modalities are available, such as microanalysis, scanning selected areas, or depth profiling techniques. Surface scanning is particularly profitable since 2D element distribution maps are much more understandable than the results of individual analyses. Information on the layered structure of the painting can be also obtained by handheld portable systems. Results presented in our paper combine 2D element distribution maps obtained by scanning analysis, and depth profiling using conventional XRF. The latter is very suitable for objects of art, as it can be evaluated from data measured with portable XRF device. Depth profiling by conventional XRF is based on the differences in X-ray absorption in paint layers. The XRF technique was applied for analysis of panel paintings of the Master of the St George Altarpiece who was active in Prague in the 1470s and 1480s. The results were evaluated by taking micro-samples and performing a material analysis.

Photocurrent mapping of near-field optical antenna resonances

NASA Astrophysics Data System (ADS)

Barnard, Edward S.; Pala, Ragip A.; Brongersma, Mark L.

2011-09-01

An increasing number of photonics applications make use of nanoscale optical antennas that exhibit a strong, resonant interaction with photons of a specific frequency. The resonant properties of such antennas are conventionally characterized by far-field light-scattering techniques. However, many applications require quantitative knowledge of the near-field behaviour, and existing local field measurement techniques provide only relative, rather than absolute, data. Here, we demonstrate a photodetector platform that uses a silicon-on-insulator substrate to spectrally and spatially map the absolute values of enhanced fields near any type of optical antenna by transducing local electric fields into photocurrent. We are able to quantify the resonant optical and materials properties of nanoscale (~50 nm) and wavelength-scale (~1 µm) metallic antennas as well as high-refractive-index semiconductor antennas. The data agree well with light-scattering measurements, full-field simulations and intuitive resonator models.

Photogrammetry of the three-dimensional shape and texture of a nanoscale particle using scanning electron microscopy and free software.

PubMed

Gontard, Lionel C; Schierholz, Roland; Yu, Shicheng; Cintas, Jesús; Dunin-Borkowski, Rafal E

2016-10-01

We apply photogrammetry in a scanning electron microscope (SEM) to study the three-dimensional shape and surface texture of a nanoscale LiTi2(PO4)3 particle. We highlight the fact that the technique can be applied non-invasively in any SEM using free software (freeware) and does not require special sample preparation. Three-dimensional information is obtained in the form of a surface mesh, with the texture of the sample stored as a separate two-dimensional image (referred to as a UV Map). The mesh can be used to measure parameters such as surface area, volume, moment of inertia and center of mass, while the UV map can be used to study the surface texture using conventional image processing techniques. We also illustrate the use of 3D printing to visualize the reconstructed model. Copyright © 2016 Elsevier B.V. All rights reserved.

Tomographic phase microscopy and its biological applications

NASA Astrophysics Data System (ADS)

Choi, Wonshik

2012-12-01

Conventional interferometric microscopy techniques such as digital holographic microscopy and quantitative phase microscopy are often classified as 3D imaging techniques because a recorded complex field image can be numerically propagated to a different depth. In a strict sense, however, a single complex field image contains only 2D information on a specimen. The measured 2D image is only a subset of the 3D structure. For the 3D mapping of an object, multiple independent 2D images are to be taken, for example at multiple incident angles or wavelengths, and then combined by the so-called optical diffraction tomography (ODT). In this Letter, tomographic phase microscopy (TPM) is reviewed that experimentally realizes the concept of the ODT for the 3D mapping of biological cells in their native state, and some of its interesting biological and biomedical applications are introduced. [Figure not available: see fulltext.

Recent advancements in nanoelectrodes and nanopipettes used in combined scanning electrochemical microscopy techniques.

PubMed

Kranz, Christine

2014-01-21

In recent years, major developments in scanning electrochemical microscopy (SECM) have significantly broadened the application range of this electroanalytical technique from high-resolution electrochemical imaging via nanoscale probes to large scale mapping using arrays of microelectrodes. A major driving force in advancing the SECM methodology is based on developing more sophisticated probes beyond conventional micro-disc electrodes usually based on noble metals or carbon microwires. This critical review focuses on the design and development of advanced electrochemical probes particularly enabling combinations of SECM with other analytical measurement techniques to provide information beyond exclusively measuring electrochemical sample properties. Consequently, this critical review will focus on recent progress and new developments towards multifunctional imaging.

VLBI Analysis with the Multi-Technique Software GEOSAT

NASA Technical Reports Server (NTRS)

Kierulf, Halfdan Pascal; Andersen, Per-Helge; Boeckmann, Sarah; Kristiansen, Oddgeir

2010-01-01

GEOSAT is a multi-technique geodetic analysis software developed at Forsvarets Forsknings Institutt (Norwegian defense research establishment). The Norwegian Mapping Authority has now installed the software and has, together with Forsvarets Forsknings Institutt, adapted the software to deliver datum-free normal equation systems in SINEX format. The goal is to be accepted as an IVS Associate Analysis Center and to provide contributions to the IVS EOP combination on a routine basis. GEOSAT is based on an upper diagonal factorized Kalman filter which allows estimation of time variable parameters like the troposphere and clocks as stochastic parameters. The tropospheric delays in various directions are mapped to tropospheric zenith delay using ray-tracing. Meteorological data from ECMWF with a resolution of six hours is used to perform the ray-tracing which depends both on elevation and azimuth. Other models are following the IERS and IVS conventions. The Norwegian Mapping Authority has submitted test SINEX files produced with GEOSAT to IVS. The results have been compared with the existing IVS combined products. In this paper the outcome of these comparisons is presented.

In vivo inflammation mapping of periodontal disease based on diffuse reflectance spectral imaging: a clinical study

NASA Astrophysics Data System (ADS)

Prasanth, Chandra Sekhar; Betsy, Joseph; Jayanthi, Jayaraj L.; Nisha, Unni G.; Prasantila, Janam; Subhash, Narayanan

2013-02-01

Since conventional techniques using periodontal probes have inherent drawbacks in the diagnosis of different grades of gingival inflammation, development of noninvasive screening devices becomes significant. Diffuse reflectance (DR) spectra recorded with white light illumination is utilized to detect periodontal inflammation from the oxygenated hemoglobin absorption ratio R620/R575. A multispectral imaging system is utilized to record narrow-band DR images at 575 and 620 nm from the anterior sextant of the gingivia of 15 healthy volunteers and 25 patients (N=40). An experienced periodontist assesses the level of gingival inflammation at each site through periodontal probing and assigns diagnosis as healthy, mild, moderate, or severe inflammation. The DR image ratio R620/R575 computed for each pixel (8-μm resolution) from the monochrome images is pseudo-color-mapped to identify gingival inflammation sites. The DR image ratio values at each site are compared with clinical diagnosis to estimate the specificity and sensitivity of the DR imaging technique in inflammation mapping. The high diagnostic accuracy is utilized to detect underlying inflammation in six patients with a previous history of periodontitis.

Communicating and visualizing data quality through Web Map Services

NASA Astrophysics Data System (ADS)

Roberts, Charles; Blower, Jon; Maso, Joan; Diaz, Daniel; Griffiths, Guy; Lewis, Jane

2014-05-01

The sharing and visualization of environmental data through OGC Web Map Services is becoming increasingly common. However, information about the quality of data is rarely presented. (In this presentation we consider mostly data uncertainty as a measure of quality, although we acknowledge that many other quality measures are relevant to the geoscience community.) In the context of the GeoViQua project (http://www.geoviqua.org) we have developed conventions and tools for using WMS to deliver data quality information. The "WMS-Q" convention describes how the WMS specification can be used to publish quality information at the level of datasets, variables and individual pixels (samples). WMS-Q requires no extensions to the WMS 1.3.0 specification, being entirely backward-compatible. (An earlier version of WMS-Q was published as OGC Engineering Report 12-160.) To complement the WMS-Q convention, we have also developed extensions to the OGC Symbology Encoding (SE) specification, enabling uncertain geoscience data to be portrayed using a variety of visualization techniques. These include contours, stippling, blackening, whitening, opacity, bivariate colour maps, confidence interval triangles and glyphs. There may also be more extensive applications of these methods beyond the visual representation of uncertainty. In this presentation we will briefly describe the scope of the WMS-Q and "extended SE" specifications and then demonstrate the innovations using open-source software based upon ncWMS (http://ncwms.sf.net). We apply the tools to a variety of datasets including Earth Observation data from the European Space Agency's Climate Change Initiative. The software allows uncertain raster data to be shared through Web Map Services, giving the user fine control over data visualization.

Synthetic Biology: Mapping the Scientific Landscape

PubMed Central

Oldham, Paul; Hall, Stephen; Burton, Geoff

2012-01-01

This article uses data from Thomson Reuters Web of Science to map and analyse the scientific landscape for synthetic biology. The article draws on recent advances in data visualisation and analytics with the aim of informing upcoming international policy debates on the governance of synthetic biology by the Subsidiary Body on Scientific, Technical and Technological Advice (SBSTTA) of the United Nations Convention on Biological Diversity. We use mapping techniques to identify how synthetic biology can best be understood and the range of institutions, researchers and funding agencies involved. Debates under the Convention are likely to focus on a possible moratorium on the field release of synthetic organisms, cells or genomes. Based on the empirical evidence we propose that guidance could be provided to funding agencies to respect the letter and spirit of the Convention on Biological Diversity in making research investments. Building on the recommendations of the United States Presidential Commission for the Study of Bioethical Issues we demonstrate that it is possible to promote independent and transparent monitoring of developments in synthetic biology using modern information tools. In particular, public and policy understanding and engagement with synthetic biology can be enhanced through the use of online interactive tools. As a step forward in this process we make existing data on the scientific literature on synthetic biology available in an online interactive workbook so that researchers, policy makers and civil society can explore the data and draw conclusions for themselves. PMID:22539946

Anatomo-clinical overlapping maps (AnaCOM): a new method to create anatomo-functional maps from neuropsychological tests and structural MRI scan of subjects with brain lesions

NASA Astrophysics Data System (ADS)

Kinkingnehun, Serge R. J.; du Boisgueheneuc, Foucaud; Golmard, Jean-Louis; Zhang, Sandy X.; Levy, Richard; Dubois, Bruno

2004-04-01

We have developed a new technique to analyze correlations between brain anatomy and its neurological functions. The technique is based on the anatomic MRI of patients with brain lesions who are administered neuropsychological tests. Brain lesions of the MRI scans are first manually segmented. The MRI volumes are then normalized to a reference map, using the segmented area as a mask. After normalization, the brain lesions of the MRI are segmented again in order to redefine the border of the lesions in the context of the normalized brain. Once the MRI is segmented, the patient's score on the neuropsychological test is assigned to each voxel in the lesioned area, while the rest of the voxels of the image are set to 0. Subsequently, the individual patient's MRI images are superimposed, and each voxel is reassigned the average score of the patients who have a lesion at that voxel. A threshold is applied to remove regions having less than three overlaps. This process leads to an anatomo-functional map that links brain areas to functional loss. Other maps can be created to aid in analyzing the functional maps, such as one that indicates the 95% confidence interval of the averaged scores for each area. This anatomo-clinical overlapping map (AnaCOM) method was used to obtain functional maps from patients with lesions in the superior frontal gyrus. By finding particular subregions more responsible for a particular deficit, this method can generate new hypotheses to be tested by conventional group methods.

Cross-correlation analysis of pulse wave propagation in arteries: in vitro validation and in vivo feasibility.

PubMed

Nauleau, Pierre; Apostolakis, Iason; McGarry, Matthew; Konofagou, Elisa

2018-05-29

The stiffness of the arteries is known to be an indicator of the progression of various cardiovascular diseases. Clinically, the pulse wave velocity (PWV) is used as a surrogate for arterial stiffness. Pulse wave imaging (PWI) is a non-invasive, ultrasound-based imaging technique capable of mapping the motion of the vessel walls, allowing the local assessment of arterial properties. Conventionally, a distinctive feature of the displacement wave (e.g. the 50% upstroke) is tracked across the map to estimate the PWV. However, the presence of reflections, such as those generated at the carotid bifurcation, can bias the PWV estimation. In this paper, we propose a two-step cross-correlation based method to characterize arteries using the information available in the PWI spatio-temporal map. First, the area under the cross-correlation curve is proposed as an index for locating the regions of different properties. Second, a local peak of the cross-correlation function is tracked to obtain a less biased estimate of the PWV. Three series of experiments were conducted in phantoms to evaluate the capabilities of the proposed method compared with the conventional method. In the ideal case of a homogeneous phantom, the two methods performed similarly and correctly estimated the PWV. In the presence of reflections, the proposed method provided a more accurate estimate than conventional processing: e.g. for the soft phantom, biases of  -0.27 and -0.71 m · s -1 were observed. In a third series of experiments, the correlation-based method was able to locate two regions of different properties with an error smaller than 1 mm. It also provided more accurate PWV estimates than conventional processing (biases:  -0.12 versus -0.26 m · s -1 ). Finally, the in vivo feasibility of the proposed method was demonstrated in eleven healthy subjects. The results indicate that the correlation-based method might be less precise in vivo but more accurate than the conventional method.

Searching for anomalous methane in shallow groundwater near shale gas wells

NASA Astrophysics Data System (ADS)

Li, Zhenhui; You, Cheng; Gonzales, Matthew; Wendt, Anna K.; Wu, Fei; Brantley, Susan L.

2016-12-01

Since the 1800s, natural gas has been extracted from wells drilled into conventional reservoirs. Today, gas is also extracted from shale using high-volume hydraulic fracturing (HVHF). These wells sometimes leak methane and must be re-sealed with cement. Some researchers argue that methane concentrations, C, increase in groundwater near shale-gas wells and that ;fracked; wells leak more than conventional wells. We developed techniques to mine datasets of groundwater chemistry in Pennsylvania townships where contamination had been reported. Values of C measured in shallow private water wells were discovered to increase with proximity to faults and to conventional, but not shale-gas, wells in the entire area. However, in small subareas, C increased with proximity to some shale-gas wells. Data mining was used to map a few hotspots where C significantly correlates with distance to faults and gas wells. Near the hotspots, 3 out of 132 shale-gas wells ( 2%) and 4 out of 15 conventional wells (27%) intersect faults at depths where they are reported to be uncased or uncemented. These results demonstrate that even though these data techniques do not establish causation, they can elucidate the controls on natural methane emission along faults and may have implications for gas well construction.

Searching for anomalous methane in shallow groundwater near shale gas wells.

PubMed

Li, Zhenhui; You, Cheng; Gonzales, Matthew; Wendt, Anna K; Wu, Fei; Brantley, Susan L

2016-12-01

Since the 1800s, natural gas has been extracted from wells drilled into conventional reservoirs. Today, gas is also extracted from shale using high-volume hydraulic fracturing (HVHF). These wells sometimes leak methane and must be re-sealed with cement. Some researchers argue that methane concentrations, C, increase in groundwater near shale-gas wells and that "fracked" wells leak more than conventional wells. We developed techniques to mine datasets of groundwater chemistry in Pennsylvania townships where contamination had been reported. Values of C measured in shallow private water wells were discovered to increase with proximity to faults and to conventional, but not shale-gas, wells in the entire area. However, in small subareas, C increased with proximity to some shale-gas wells. Data mining was used to map a few hotspots where C significantly correlates with distance to faults and gas wells. Near the hotspots, 3 out of 132 shale-gas wells (~2%) and 4 out of 15 conventional wells (27%) intersect faults at depths where they are reported to be uncased or uncemented. These results demonstrate that even though these data techniques do not establish causation, they can elucidate the controls on natural methane emission along faults and may have implications for gas well construction. Copyright © 2016 Elsevier B.V. All rights reserved.

Land-based lidar mapping: a new surveying technique to shed light on rapid topographic change

USGS Publications Warehouse

Collins, Brian D.; Kayen, Robert

2006-01-01

The rate of natural change in such dynamic environments as rivers and coastlines can sometimes overwhelm the monitoring capacity of conventional surveying methods. In response to this limitation, U.S. Geological Survey (USGS) scientists are pioneering new applications of light detection and ranging (lidar), a laser-based scanning technology that promises to greatly increase our ability to track rapid topographic changes and manage their impact on affected communities.

Case studies on the geological application of LANDSAT imagery in Brazil. [Sao Domingos Range, Pocos de Caldas, and Araguaia and Tocantins Rivers

NASA Technical Reports Server (NTRS)

Demendonca, F. (Principal Investigator); Correa, A. C.; Liu, C. C.

1975-01-01

The author has identified the following significant results. Sao Domingos Range, Pocos de Caldas, and Araguaia and Tocantins Rivers in Brazil were selected as test sites for LANDSAT imagery. The satellite images were analyzed using conventional photointerpretation techniques, and the results indicate the application of small scale image data in regional structural data analysis, geological mapping, and mineral exploration.

Non-destructive testing for the structures and civil infrastructures characterization

NASA Astrophysics Data System (ADS)

Capozzoli, L.; Rizzo, E.

2012-04-01

This work evaluates the ability of non-conventional NDT techniques such as GPR, geoelectrical method and conventional ones such as infrared thermography (IRT) and sonic test for the characterization of building structures in laboratory and in-situ. Moreover, the integration of the different techniques were evaluated in order to reduce the degree of uncertainties associated. The presence of electromagnetic, resistivity or thermal anomalies in the behavior may be related to the presence of defects, crack, decay or moisture. The research was conducted in two phases: the first phase was performed in laboratory and the second one mainly in the field work. The laboratory experiments proceeded to calibrate the geophysical techniques GPR and geoelectrical method on building structures. A multi-layer structure was reconstructed in laboratory, in order to simulate a back-bridge: asphalt, reinforced concrete, sand and gravel layers. In the deep sandy layer, PVC, aluminum and steel pipes were introduced. This structure has also been brought to crack in a predetermined area and hidden internal fractures were investigated. GPR has allowed to characterize the panel in a non-invasive mode; radar maps were developed using various algorithms during post-process about 2D maps and 3D models with aerial acquisition of 400 MHz, 900MHz, 1500MHz, 2000MHz. Geoelectrical testing was performed with a network of 25 electrodes spaced at mutual distance of 5 cm. Two different configurations were used dipole-dipole and pole-dipole approaches. In the second phase, we proceeded to the analysis of pre-tensioned concrete in order to detect the possible presence of criticality in the structure. For this purpose by GPR 2GHz antenna, a '70 years precast bridge characterized by a high state of decay was studied; then were also analyzed a pillar and a beam of recent production directly into the processing plant. Moreover, results obtained using GPR were compared with those obtained through the use of infrared thermography and sonic testing. Finally, we investigated a radiant floor by GPR (900 MHz to 2000 MHz antennas) and long-wave infrared camera. Non-destructive diagnostic techniques allow to investigate a building structure in reinforced concrete or masonry without altering the characteristics of the element investigated. For this reason, geo-electrical and electromagnetic surveys of masonry are a suitable non-destructive tool for the diagnosis of a deteriorated concrete structure. Moreover, the integration of different NDT techniques (conventional and no-conventional) is a very powerful to maximize the capabilities and to compensate for the limitations of each method.

Fast Lesion Mapping during HIFU Treatment Using Harmonic Motion Imaging guided Focused Ultrasound (HMIgFUS) In Vitro and In Vivo

PubMed Central

Han, Yang; Wang, Shutao; Payen, Thomas; Konofagou, Elisa

2017-01-01

The successful clinical application of High Intensity Focused Ultrasound (HIFU) ablation depends on reliable monitoring of the lesion formation. Harmonic Motion Imaging guided Focused Ultrasound (HMIgFUS) is an ultrasound-based elasticity imaging technique, which monitors HIFU ablation based on the stiffness change of the tissue instead of the echo intensity change in conventional B-mode monitoring, rendering it potentially more sensitive to lesion development. Our group has shown that predicting the lesion location based on the radiation force-excited region is feasible during HMIgFUS. In this study, the feasibility of a fast lesion mapping method is explored to directly monitor the lesion map during HIFU. The HMI lesion map was generated by subtracting the reference HMI image from the present HMI peak-to-peak displacement map to be streamed on the computer display. The dimensions of the HMIgFUS lesions were compared against gross pathology. Excellent agreement was found between the lesion depth (r2 = 0.81, slope = 0.90), width (r2 = 0.85, slope = 1.12) and area (r2 = 0.58, slope = 0.75). In vivo feasibility was assessed in a mouse with a pancreatic tumor. These findings demonstrate that HMIgFUS can successfully map thermal lesion and monitor lesion development in real time in vitro and in vivo. The HMIgFUS technique may therefore constitute a novel clinical tool for HIFU treatment monitoring. PMID:28323638

Particle displacement tracking applied to air flows

NASA Technical Reports Server (NTRS)

Wernet, Mark P.

1991-01-01

Electronic Particle Image Velocimeter (PIV) techniques offer many advantages over conventional photographic PIV methods such as fast turn around times and simplified data reduction. A new all electronic PIV technique was developed which can measure high speed gas velocities. The Particle Displacement Tracking (PDT) technique employs a single cw laser, small seed particles (1 micron), and a single intensified, gated CCD array frame camera to provide a simple and fast method of obtaining two-dimensional velocity vector maps with unambiguous direction determination. Use of a single CCD camera eliminates registration difficulties encountered when multiple cameras are used to obtain velocity magnitude and direction information. An 80386 PC equipped with a large memory buffer frame-grabber board provides all of the data acquisition and data reduction operations. No array processors of other numerical processing hardware are required. Full video resolution (640x480 pixel) is maintained in the acquired images, providing high resolution video frames of the recorded particle images. The time between data acquisition to display of the velocity vector map is less than 40 sec. The new electronic PDT technique is demonstrated on an air nozzle flow with velocities less than 150 m/s.

Four-Dimensional Ultrafast Electron Microscopy: Insights into an Emerging Technique.

PubMed

Adhikari, Aniruddha; Eliason, Jeffrey K; Sun, Jingya; Bose, Riya; Flannigan, David J; Mohammed, Omar F

2017-01-11

Four-dimensional ultrafast electron microscopy (4D-UEM) is a novel analytical technique that aims to fulfill the long-held dream of researchers to investigate materials at extremely short spatial and temporal resolutions by integrating the excellent spatial resolution of electron microscopes with the temporal resolution of ultrafast femtosecond laser-based spectroscopy. The ingenious use of pulsed photoelectrons to probe surfaces and volumes of materials enables time-resolved snapshots of the dynamics to be captured in a way hitherto impossible by other conventional techniques. The flexibility of 4D-UEM lies in the fact that it can be used in both the scanning (S-UEM) and transmission (UEM) modes depending upon the type of electron microscope involved. While UEM can be employed to monitor elementary structural changes and phase transitions in samples using real-space mapping, diffraction, electron energy-loss spectroscopy, and tomography, S-UEM is well suited to map ultrafast dynamical events on materials surfaces in space and time. This review provides an overview of the unique features that distinguish these techniques and also illustrates the applications of both S-UEM and UEM to a multitude of problems relevant to materials science and chemistry.

High Resolution Stratigraphic Mapping in Complex Terrain: A Comparison of Traditional Remote Sensing Techniques with Unmanned Aerial Vehicle - Structure from Motion Photogrammetry

NASA Astrophysics Data System (ADS)

Nesbit, P. R.; Hugenholtz, C.; Durkin, P.; Hubbard, S. M.; Kucharczyk, M.; Barchyn, T.

2016-12-01

Remote sensing and digital mapping have started to revolutionize geologic mapping in recent years as a result of their realized potential to provide high resolution 3D models of outcrops to assist with interpretation, visualization, and obtaining accurate measurements of inaccessible areas. However, in stratigraphic mapping applications in complex terrain, it is difficult to acquire information with sufficient detail at a wide spatial coverage with conventional techniques. We demonstrate the potential of a UAV and Structure from Motion (SfM) photogrammetric approach for improving 3D stratigraphic mapping applications within a complex badland topography. Our case study is performed in Dinosaur Provincial Park (Alberta, Canada), mapping late Cretaceous fluvial meander belt deposits of the Dinosaur Park formation amidst a succession of steeply sloping hills and abundant drainages - creating a challenge for stratigraphic mapping. The UAV-SfM dataset (2 cm spatial resolution) is compared directly with a combined satellite and aerial LiDAR dataset (30 cm spatial resolution) to reveal advantages and limitations of each dataset before presenting a unique workflow that utilizes the dense point cloud from the UAV-SfM dataset for analysis. The UAV-SfM dense point cloud minimizes distortion, preserves 3D structure, and records an RGB attribute - adding potential value in future studies. The proposed UAV-SfM workflow allows for high spatial resolution remote sensing of stratigraphy in complex topographic environments. This extended capability can add value to field observations and has the potential to be integrated with subsurface petroleum models.

Simultaneous topography and tomography of latent fingerprints using full-field swept-source optical coherence tomography

NASA Astrophysics Data System (ADS)

Dubey, Satish Kumar; Singh Mehta, Dalip; Anand, Arun; Shakher, Chandra

2008-01-01

We demonstrate simultaneous topography and tomography of latent fingerprints using full-field swept-source optical coherence tomography (OCT). The swept-source OCT system comprises a superluminescent diode (SLD) as broad-band light source, an acousto-optic tunable filter (AOTF) as frequency tuning device, and a compact, nearly common-path interferometer. Both the amplitude and the phase map of the interference fringe signal are reconstructed. Optical sectioning of the latent fingerprint sample is obtained by selective Fourier filtering and the topography is retrieved from the phase map. Interferometry, selective filtering, low coherence and hence better resolution are some of the advantages of the proposed system over the conventional fingerprint detection techniques. The present technique is non-invasive in nature and does not require any physical or chemical processing. Therefore, the quality of the sample does not alter and hence the same fingerprint can be used for other types of forensic test. Exploitation of low-coherence interferometry for fingerprint detection itself provides an edge over other existing techniques as fingerprints can even be lifted from low-reflecting surfaces. The proposed system is very economical and compact.

New Ground Truth Capability from InSAR Time Series Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buckley, S; Vincent, P; Yang, D

2005-07-13

We demonstrate that next-generation interferometric synthetic aperture radar (InSAR) processing techniques applied to existing data provide rich InSAR ground truth content for exploitation in seismic source identification. InSAR time series analyses utilize tens of interferograms and can be implemented in different ways. In one such approach, conventional InSAR displacement maps are inverted in a final post-processing step. Alternatively, computationally intensive data reduction can be performed with specialized InSAR processing algorithms. The typical final result of these approaches is a synthesized set of cumulative displacement maps. Examples from our recent work demonstrate that these InSAR processing techniques can provide appealing newmore » ground truth capabilities. We construct movies showing the areal and temporal evolution of deformation associated with previous nuclear tests. In other analyses, we extract time histories of centimeter-scale surface displacement associated with tunneling. The potential exists to identify millimeter per year surface movements when sufficient data exists for InSAR techniques to isolate and remove phase signatures associated with digital elevation model errors and the atmosphere.« less

Automatic transfer function generation for volume rendering of high-resolution x-ray 3D digital mammography images

NASA Astrophysics Data System (ADS)

Alyassin, Abdal M.

2002-05-01

3D Digital mammography (3DDM) is a new technology that provides high resolution X-ray breast tomographic data. Like any other tomographic medical imaging modalities, viewing a stack of tomographic images may require time especially if the images are of large matrix size. In addition, it may cause difficulty to conceptually construct 3D breast structures. Therefore, there is a need to readily visualize the data in 3D. However, one of the issues that hinder the usage of volume rendering (VR) is finding an automatic way to generate transfer functions that efficiently map the important diagnostic information in the data. We have developed a method that randomly samples the volume. Based on the mean and the standard deviation of these samples, the technique determines the lower limit and upper limit of a piecewise linear ramp transfer function. We have volume rendered several 3DDM data using this technique and compared visually the outcome with the result from a conventional automatic technique. The transfer function generated through the proposed technique provided superior VR images over the conventional technique. Furthermore, the improvement in the reproducibility of the transfer function correlated with the number of samples taken from the volume at the expense of the processing time.

Seismic migration in generalized coordinates

NASA Astrophysics Data System (ADS)

Arias, C.; Duque, L. F.

2017-06-01

Reverse time migration (RTM) is a technique widely used nowadays to obtain images of the earth’s sub-surface, using artificially produced seismic waves. This technique has been developed for zones with flat surface and when applied to zones with rugged topography some corrections must be introduced in order to adapt it. This can produce defects in the final image called artifacts. We introduce a simple mathematical map that transforms a scenario with rugged topography into a flat one. The three steps of the RTM can be applied in a way similar to the conventional ones just by changing the Laplacian in the acoustic wave equation for a generalized one. We present a test of this technique using the Canadian foothills SEG velocity model.

White matter tractography by means of Turboprop diffusion tensor imaging.

PubMed

Arfanakis, Konstantinos; Gui, Minzhi; Lazar, Mariana

2005-12-01

White matter fiber-tractography by means of diffusion tensor imaging (DTI) is a noninvasive technique that provides estimates of the structural connectivity of the brain. However, conventional fiber-tracking methods using DTI are based on echo-planar image acquisitions (EPI), which suffer from image distortions and artifacts due to magnetic susceptibility variations and eddy currents. Thus, a large percentage of white matter fiber bundles that are mapped using EPI-based DTI data are distorted, and/or terminated early, while others are completely undetected. This severely limits the potential of fiber-tracking techniques. In contrast, Turboprop imaging is a multiple-shot gradient and spin-echo (GRASE) technique that provides images with significantly fewer susceptibility and eddy current-related artifacts than EPI. The purpose of this work was to evaluate the performance of fiber-tractography techniques when using data obtained with Turboprop-DTI. All fiber pathways that were mapped were found to be in agreement with the anatomy. There were no visible distortions in any of the traced fiber bundles, even when these were located in the vicinity of significant magnetic field inhomogeneities. Additionally, the Turboprop-DTI data used in this research were acquired in less than 19 min of scan time. Thus, Turboprop appears to be a promising DTI data acquisition technique for tracing white matter fibers.

Complementary and conventional medicine: a concept map

PubMed Central

Baldwin, Carol M; Kroesen, Kendall; Trochim, William M; Bell, Iris R

2004-01-01

Background Despite the substantive literature from survey research that has accumulated on complementary and alternative medicine (CAM) in the United States and elsewhere, very little research has been done to assess conceptual domains that CAM and conventional providers would emphasize in CAM survey studies. The objective of this study is to describe and interpret the results of concept mapping with conventional and CAM practitioners from a variety of backgrounds on the topic of CAM. Methods Concept mapping, including free sorts, ratings, and multidimensional scaling was used to organize conceptual domains relevant to CAM into a visual "cluster map." The panel consisted of CAM providers, conventional providers, and university faculty, and was convened to help formulate conceptual domains to guide the development of a CAM survey for use with United States military veterans. Results Eight conceptual clusters were identified: 1) Self-assessment, Self-care, and Quality of Life; 2) Health Status, Health Behaviors; 3) Self-assessment of Health; 4) Practical/Economic/ Environmental Concerns; 5) Needs Assessment; 6) CAM vs. Conventional Medicine; 7) Knowledge of CAM; and 8) Experience with CAM. The clusters suggest panelists saw interactions between CAM and conventional medicine as a critical component of the current medical landscape. Conclusions Concept mapping provided insight into how CAM and conventional providers view the domain of health care, and was shown to be a useful tool in the formulation of CAM-related conceptual domains. PMID:15018623

Remote sensing and geographic information system for appraisal of salt-affected soils in India.

PubMed

Singh, Gurbachan; Bundela, D S; Sethi, Madhurama; Lal, Khajanchi; Kamra, S K

2010-01-01

Quantification of the nature, extent, and spatial distribution of salt-affected soils (SAS) for India and the world is essential for planning and implementing reclamation programs in a timely and cost-effective manner for sustained crop production. The national extent of SAS for India over the last four decades was assessed by conventional and remote sensing approaches using diverse methodologies and class definitions and ranged from 6.0 to 26.1 million hectares (Mha) and 1.2 to 10.1 Mha, respectively. In 1966, an area of 6 Mha under SAS was first reported using the former approach. Three national estimates, obtained using remote sensing, were reconciled using a geographic information system, resulting in an acceptable extent of 6.73 Mha. Moderately and severely salt-encrusted lands having large contiguous area have been correctly mapped, but slightly salt-encrusted land having smaller affected areas within croplands has not been accurately mapped. Recent satellite sensors (e.g., Resourcesat-1, Cartosat-2, IKONOS-II, and RISAT-2), along with improved image processing techniques integrated with terrain and other spatial data using a geographic information system, are enabling mapping at large scale. Significant variations in salt encrustation at the surface caused by soil moisture, waterlogging conditions, salt-tolerant crops, and dynamics of subsurface salts present constraints in appraisal, delineation, and mapping efforts. The article provides an overview of development, identification, characterization, and delineation of SAS, past and current national scenarios of SAS using conventional and remote sensing approaches, reconciliation of national estimates, issues of SAS mapping, and future scope.

The use of remote sensing in solving Florida's geological and coastal engineering problems

NASA Technical Reports Server (NTRS)

Brooks, H. K.; Ruth, B. E.; Wang, Y. H.; Ferguson, R. L.

1977-01-01

LANDSAT imagery and NASA high altitude color infrared (CIR) photography were used to select suitable sites for sanitary landfill in Volusia County, Florida and to develop techniques for preventing sand deposits in the Clearwater inlet. Activities described include the acquisition of imagery, its analysis by the IMAGE 100 system, conventional photointerpretation, evaluation of existing data sources (vegetation, soil, and ground water maps), site investigations for ground truth, and preparation of displays for reports.

Diagnosis of Familial Wolf-Hirschhorn Syndrome due to a Paternal Cryptic Chromosomal Rearrangement by Conventional and Molecular Cytogenetic Techniques

PubMed Central

Venegas-Vega, Carlos A.; Zepeda, Luis M.; Garduño-Zarazúa, Luz M.; Berumen, Jaime; Kofman, Susana; Cervantes, Alicia

2013-01-01

The use of conventional cytogenetic techniques in combination with fluorescent in situ hybridization (FISH) and single-nucleotide polymorphism (SNP) microarrays is necessary for the identification of cryptic rearrangements in the diagnosis of chromosomal syndromes. We report two siblings, a boy of 9 years and 9 months of age and his 7-years- and 5-month-old sister, with the classic Wolf-Hirschhorn syndrome (WHS) phenotype. Using high-resolution GTG- and NOR-banding karyotypes, as well as FISH analysis, we characterized a pure 4p deletion in both sibs and a balanced rearrangement in their father, consisting in an insertion of 4p material within a nucleolar organizing region of chromosome 15. Copy number variant (CNV) analysis using SNP arrays showed that both siblings have a similar size of 4p deletion (~6.5 Mb). Our results strongly support the need for conventional cytogenetic and FISH analysis, as well as high-density microarray mapping for the optimal characterization of the genetic imbalance in patients with WHS; parents must always be studied for recognizing cryptic balanced chromosomal rearrangements for an adequate genetic counseling. PMID:23484094

Pixel-by-pixel absolute phase retrieval using three phase-shifted fringe patterns without markers

NASA Astrophysics Data System (ADS)

Jiang, Chufan; Li, Beiwen; Zhang, Song

2017-04-01

This paper presents a method that can recover absolute phase pixel by pixel without embedding markers on three phase-shifted fringe patterns, acquiring additional images, or introducing additional hardware component(s). The proposed three-dimensional (3D) absolute shape measurement technique includes the following major steps: (1) segment the measured object into different regions using rough priori knowledge of surface geometry; (2) artificially create phase maps at different z planes using geometric constraints of structured light system; (3) unwrap the phase pixel by pixel for each region by properly referring to the artificially created phase map; and (4) merge unwrapped phases from all regions into a complete absolute phase map for 3D reconstruction. We demonstrate that conventional three-step phase-shifted fringe patterns can be used to create absolute phase map pixel by pixel even for large depth range objects. We have successfully implemented our proposed computational framework to achieve absolute 3D shape measurement at 40 Hz.

A study of atmospheric effects on pattern recognition devices. [Sacramento Valley, California

NASA Technical Reports Server (NTRS)

Thomson, F. J. (Principal Investigator); Sadowski, F. G.

1975-01-01

The author has identified the following significant results. ERTS-1 imagery can be applied in the broadscale assessment of forest resources as a supplement to aerial photography and field survey. There was no application to inventory of crop and pasture diseases mainly because of poor quality and low resolution, and unreliability of image acquisition. Inventory of soil erosion was satisfactory in humid eastern New South Wales, but not in semi-arid areas. Patterns of snow cover, areas of water in natural and artificial water bodies, extent of bushfires, and location of coastal mobile sand bodies were readily apparent. ERTS-1 imagery was judged to be a valuable addition to conventional techniques of regional small scale geological mapping. ERTS data was successfully used to map flooding and flood progression. The imagery was found suitable for mapping at 1:1,000,000 scale both on the mainland and in Antarctica, but did not meet accuracy specifications for 1:250,000 mapping.

Fast IR laser mapping ellipsometry for the study of functional organic thin films.

PubMed

Furchner, Andreas; Sun, Guoguang; Ketelsen, Helge; Rappich, Jörg; Hinrichs, Karsten

2015-03-21

Fast infrared mapping with sub-millimeter lateral resolution as well as time-resolved infrared studies of kinetic processes of functional organic thin films require a new generation of infrared ellipsometers. We present a novel laboratory-based infrared (IR) laser mapping ellipsometer, in which a laser is coupled to a variable-angle rotating analyzer ellipsometer. Compared to conventional Fourier-transform infrared (FT-IR) ellipsometers, the IR laser ellipsometer provides ten- to hundredfold shorter measurement times down to 80 ms per measured spot, as well as about tenfold increased lateral resolution of 120 μm, thus enabling mapping of small sample areas with thin-film sensitivity. The ellipsometer, equipped with a HeNe laser emitting at about 2949 cm(-1), was applied for the optical characterization of inhomogeneous poly(3-hexylthiophene) [P3HT] and poly(N-isopropylacrylamide) [PNIPAAm] organic thin films used for opto-electronics and bioapplications. With the constant development of tunable IR laser sources, laser-based infrared ellipsometry is a promising technique for fast in-depth mapping characterization of thin films and blends.

Improved approach for electric vehicle rapid charging station placement and sizing using Google maps and binary lightning search algorithm

PubMed Central

Shareef, Hussain; Mohamed, Azah

2017-01-01

The electric vehicle (EV) is considered a premium solution to global warming and various types of pollution. Nonetheless, a key concern is the recharging of EV batteries. Therefore, this study proposes a novel approach that considers the costs of transportation loss, buildup, and substation energy loss and that incorporates harmonic power loss into optimal rapid charging station (RCS) planning. A novel optimization technique, called binary lightning search algorithm (BLSA), is proposed to solve the optimization problem. BLSA is also applied to a conventional RCS planning method. A comprehensive analysis is conducted to assess the performance of the two RCS planning methods by using the IEEE 34-bus test system as the power grid. The comparative studies show that the proposed BLSA is better than other optimization techniques. The daily total cost in RCS planning of the proposed method, including harmonic power loss, decreases by 10% compared with that of the conventional method. PMID:29220396

Improved approach for electric vehicle rapid charging station placement and sizing using Google maps and binary lightning search algorithm.

PubMed

Islam, Md Mainul; Shareef, Hussain; Mohamed, Azah

2017-01-01

The electric vehicle (EV) is considered a premium solution to global warming and various types of pollution. Nonetheless, a key concern is the recharging of EV batteries. Therefore, this study proposes a novel approach that considers the costs of transportation loss, buildup, and substation energy loss and that incorporates harmonic power loss into optimal rapid charging station (RCS) planning. A novel optimization technique, called binary lightning search algorithm (BLSA), is proposed to solve the optimization problem. BLSA is also applied to a conventional RCS planning method. A comprehensive analysis is conducted to assess the performance of the two RCS planning methods by using the IEEE 34-bus test system as the power grid. The comparative studies show that the proposed BLSA is better than other optimization techniques. The daily total cost in RCS planning of the proposed method, including harmonic power loss, decreases by 10% compared with that of the conventional method.

Rapid Prototyping Technique for the Fabrication of Millifluidic Devices for Polymer Formulations

NASA Astrophysics Data System (ADS)

Cabral, Joao; Harrison, Christopher; Eric, Amis; Karim, Alamgir

2003-03-01

We describe a rapid prototyping technique for the fabrication of 600 micron deep fluidic channels in a solvent-resistant polymeric matrix. Using a conventional illumination source, a laser-jet printed mask, and a commercially available thioelene-based adhesive, we demonstrate the fabrication of fluidic channels which are impervious to a wide range of solvents. The fabrication of channels with this depth by conventional lithography would be both challenging and time-consuming. We demonstrate two lithography methods: one which fabricates channels sealed between glass plates (closed face) and one which fabricates structures on a single plate (open-faced). Furthermore, we demonstrate that this technology can be used to fabricate channels with a depth which varies linearly with distance. The latter is completely compatible with silicone replication technniques. Additionally, we demonstrate that siloxane-based elastomer molds of these channels can be readily made for aqueous applications. Applications to on-line phase mapping of polymer solutions (PEO-Water-Salt) and off line phase separation studies will be discussed.

Mapping power-law rheology of living cells using multi-frequency force modulation atomic force microscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Takahashi, Ryosuke; Okajima, Takaharu, E-mail: okajima@ist.hokudai.ac.jp

We present multi-frequency force modulation atomic force microscopy (AFM) for mapping the complex shear modulus G* of living cells as a function of frequency over the range of 50–500 Hz in the same measurement time as the single-frequency force modulation measurement. The AFM technique enables us to reconstruct image maps of rheological parameters, which exhibit a frequency-dependent power-law behavior with respect to G{sup *}. These quantitative rheological measurements reveal a large spatial variation in G* in this frequency range for single cells. Moreover, we find that the reconstructed images of the power-law rheological parameters are much different from those obtained inmore » force-curve or single-frequency force modulation measurements. This indicates that the former provide information about intracellular mechanical structures of the cells that are usually not resolved with the conventional force measurement methods.« less

The role of rotors in atrial fibrillation

PubMed Central

Swarup, Vijay; Narayan, Sanjiv M.

2015-01-01

Despite significant advances in our understanding of atrial fibrillation (AF) mechanisms in the last 15 years, ablation outcomes remain suboptimal. A potential reason is that many ablation techniques focus on anatomic, rather than patient-specific functional targets for ablation. Panoramic contact mapping, incorporating phase analysis, repolarization and conduction dynamics, and oscillations in AF rate, overcomes many prior difficulties with mapping AF. This approach provides evidence that the mechanisms sustaining human AF are deterministic, largely due to stable electrical rotors and focal sources in either atrium. Ablation of such sources (Focal Impulse and Rotor Modulation: FIRM ablation) has been shown to improve ablation outcome compared with conventional ablation alone; independent laboratories directly targeting stable rotors have shown similar results. Clinical trials examining the role of stand-alone FIRM ablation are in progress. Looking forward, translating insights from patient-specific mapping to evidence-based guidelines and clinical practice is the next challenge in improving patient outcomes in AF management. PMID:25713729

Facilitated assignment of large protein NMR signals with covariance sequential spectra using spectral derivatives.

PubMed

Harden, Bradley J; Nichols, Scott R; Frueh, Dominique P

2014-09-24

Nuclear magnetic resonance (NMR) studies of larger proteins are hampered by difficulties in assigning NMR resonances. Human intervention is typically required to identify NMR signals in 3D spectra, and subsequent procedures depend on the accuracy of this so-called peak picking. We present a method that provides sequential connectivities through correlation maps constructed with covariance NMR, bypassing the need for preliminary peak picking. We introduce two novel techniques to minimize false correlations and merge the information from all original 3D spectra. First, we take spectral derivatives prior to performing covariance to emphasize coincident peak maxima. Second, we multiply covariance maps calculated with different 3D spectra to destroy erroneous sequential correlations. The maps are easy to use and can readily be generated from conventional triple-resonance experiments. Advantages of the method are demonstrated on a 37 kDa nonribosomal peptide synthetase domain subject to spectral overlap.

Coniferous forest classification and inventory using Landsat and digital terrain data

NASA Technical Reports Server (NTRS)

Franklin, J.; Logan, T. L.; Woodcock, C. E.; Strahler, A. H.

1986-01-01

Machine-processing techniques were used in a Forest Classification and Inventory System (FOCIS) procedure to extract and process tonal, textural, and terrain information from registered Landsat multispectral and digital terrain data. Using FOCIS as a basis for stratified sampling, the softwood timber volumes of the Klamath National Forest and Eldorado National Forest were estimated within standard errors of 4.8 and 4.0 percent, respectively. The accuracy of these large-area inventories is comparable to the accuracy yielded by use of conventional timber inventory methods, but, because of automation, the FOCIS inventories are more rapid (9-12 months compared to 2-3 years for conventional manual photointerpretation, map compilation and drafting, field sampling, and data processing) and are less costly.

Human factors analysis for a 2D enroute moving map application

NASA Astrophysics Data System (ADS)

Pschierer, Christian; Wipplinger, Patrick; Schiefele, Jens; Cromer, Scot; Laurin, John; Haffner, Skip

2005-05-01

The paper describes flight trials performed in Centennial, CO with a Piper Cheyenne from Marinvent. Six pilots flew the Cheyenne in twelve enroute segments between Denver Centennial and Colorado Springs. Two different settings (paper chart, enroute moving map) were evaluated with randomized settings. The flight trial goal was to evaluate the objective performance of pilots compared among the different settings. As dependent variables, positional accuracy and situational awareness probe (SAP) were measured. Analysis was conducted by an ANOVA test. In parallel, all pilots answered subjective Cooper-Harper, NASA TLX, situation awareness rating technique (SART), Display Readability Rating and debriefing questionnaires. The tested enroute moving map application has Jeppesen chart compliant symbologies for high-enroute and low-enroute. It has a briefing mode were all information found on today"s enroute paper chart together with a loaded flight plan are displayed in a north-up orientation. The execution mode displays a loaded flight plan routing together with only pertinent flight route relevant information in either a track up or north up orientation. Depiction of an own ship symbol is possible in both modes. All text and symbols are deconflicted. Additional information can be obtained by clicking on symbols. Terrain and obstacle data can be displayed for enhanced situation awareness. The result shows that pilots flying the 2D enroute moving map display perform no worse than pilots with conventional systems. Flight technical error and workload are equivalent or lower, situational awareness is higher than on conventional paper charts.

Holographic quantitative imaging of sample hidden by turbid medium or occluding objects

NASA Astrophysics Data System (ADS)

Bianco, V.; Miccio, L.; Merola, F.; Memmolo, P.; Gennari, O.; Paturzo, Melania; Netti, P. A.; Ferraro, P.

2015-03-01

Digital Holography (DH) numerical procedures have been developed to allow imaging through turbid media. A fluid is considered turbid when dispersed particles provoke strong light scattering, thus destroying the image formation by any standard optical system. Here we show that sharp amplitude imaging and phase-contrast mapping of object hidden behind turbid medium and/or occluding objects are possible in harsh noise conditions and with a large field-of view by Multi-Look DH microscopy. In particular, it will be shown that both amplitude imaging and phase-contrast mapping of cells hidden behind a flow of Red Blood Cells can be obtained. This allows, in a noninvasive way, the quantitative evaluation of living processes in Lab on Chip platforms where conventional microscopy techniques fail. The combination of this technique with endoscopic imaging can pave the way for the holographic blood vessel inspection, e.g. to look for settled cholesterol plaques as well as blood clots for a rapid diagnostics of blood diseases.

Surface pressure field mapping using luminescent coatings

NASA Technical Reports Server (NTRS)

Mclachlan, B. G.; Kavandi, J. L.; Callis, J. B.; Gouterman, M.; Green, E.; Khalil, G.; Burns, D.

1993-01-01

In recent experiments we demonstrated the feasibility of using the oxygen dependence of luminescent molecules for surface pressure measurement in aerodynamic testing. This technique is based on the observation that for many luminescent molecules the light emitted increases as the oxygen partial pressure, and thus the air pressure, the molecules see decreases. In practice the surface to be observed is coated with an oxygen permeable polymer containing a luminescent molecule and illuminated with ultraviolet radiation. The airflow induced surface pressure field is seen as a luminescence intensity distribution which can be measured using quantitative video techniques. Computer processing converts the video data into a map of the surface pressure field. The experiments consisted of evaluating a trial luminescent coating in measuring the static surface pressure field over a two-dimensional NACA-0012 section model airfoil for Mach numbers ranging from 0.3 and 0.66. Comparison of the luminescent coating derived pressures were made to those obtained from conventional pressure taps. The method along with the experiment and its results will be described.

Shear wave pulse compression for dynamic elastography using phase-sensitive optical coherence tomography

NASA Astrophysics Data System (ADS)

Nguyen, Thu-Mai; Song, Shaozhen; Arnal, Bastien; Wong, Emily Y.; Huang, Zhihong; Wang, Ruikang K.; O'Donnell, Matthew

2014-01-01

Assessing the biomechanical properties of soft tissue provides clinically valuable information to supplement conventional structural imaging. In the previous studies, we introduced a dynamic elastography technique based on phase-sensitive optical coherence tomography (PhS-OCT) to characterize submillimetric structures such as skin layers or ocular tissues. Here, we propose to implement a pulse compression technique for shear wave elastography. We performed shear wave pulse compression in tissue-mimicking phantoms. Using a mechanical actuator to generate broadband frequency-modulated vibrations (1 to 5 kHz), induced displacements were detected at an equivalent frame rate of 47 kHz using a PhS-OCT. The recorded signal was digitally compressed to a broadband pulse. Stiffness maps were then reconstructed from spatially localized estimates of the local shear wave speed. We demonstrate that a simple pulse compression scheme can increase shear wave detection signal-to-noise ratio (>12 dB gain) and reduce artifacts in reconstructing stiffness maps of heterogeneous media.

Space-resolved diffusing wave spectroscopy measurements of the macroscopic deformation and the microscopic dynamics in tensile strain tests

NASA Astrophysics Data System (ADS)

Nagazi, Med-Yassine; Brambilla, Giovanni; Meunier, Gérard; Marguerès, Philippe; Périé, Jean-Noël; Cipelletti, Luca

2017-01-01

We couple a laser-based, space-resolved dynamic light scattering apparatus to a universal traction machine for mechanical extensional tests. We perform simultaneous optical and mechanical measurements on polyether ether ketone, a semi-crystalline polymer widely used in the industry. Due to the high turbidity of the sample, light is multiply scattered by the sample and the diffusing wave spectroscopy (DWS) formalism is used to interpret the data. Space-resolved DWS yields spatial maps of the sample strain and of the microscopic dynamics. An excellent agreement is found between the strain maps thus obtained and those measured by a conventional stereo-digital image correlation technique. The microscopic dynamics reveals both affine motion and plastic rearrangements. Thanks to the extreme sensitivity of DWS to displacements as small as 1 nm, plastic activity and its spatial localization can be detected at an early stage of the sample strain, making the technique presented here a valuable complement to existing material characterization methods.

Decision-level fusion of SAR and IR sensor information for automatic target detection

NASA Astrophysics Data System (ADS)

Cho, Young-Rae; Yim, Sung-Hyuk; Cho, Hyun-Woong; Won, Jin-Ju; Song, Woo-Jin; Kim, So-Hyeon

2017-05-01

We propose a decision-level architecture that combines synthetic aperture radar (SAR) and an infrared (IR) sensor for automatic target detection. We present a new size-based feature, called target-silhouette to reduce the number of false alarms produced by the conventional target-detection algorithm. Boolean Map Visual Theory is used to combine a pair of SAR and IR images to generate the target-enhanced map. Then basic belief assignment is used to transform this map into a belief map. The detection results of sensors are combined to build the target-silhouette map. We integrate the fusion mass and the target-silhouette map on the decision level to exclude false alarms. The proposed algorithm is evaluated using a SAR and IR synthetic database generated by SE-WORKBENCH simulator, and compared with conventional algorithms. The proposed fusion scheme achieves higher detection rate and lower false alarm rate than the conventional algorithms.

Fast lesion mapping during HIFU treatment using harmonic motion imaging guided focused ultrasound (HMIgFUS) in vitro and in vivo

NASA Astrophysics Data System (ADS)

Han, Yang; Wang, Shutao; Payen, Thomas; Konofagou, Elisa

2017-04-01

The successful clinical application of high intensity focused ultrasound (HIFU) ablation depends on reliable monitoring of the lesion formation. Harmonic motion imaging guided focused ultrasound (HMIgFUS) is an ultrasound-based elasticity imaging technique, which monitors HIFU ablation based on the stiffness change of the tissue instead of the echo intensity change in conventional B-mode monitoring, rendering it potentially more sensitive to lesion development. Our group has shown that predicting the lesion location based on the radiation force-excited region is feasible during HMIgFUS. In this study, the feasibility of a fast lesion mapping method is explored to directly monitor the lesion map during HIFU. The harmonic motion imaging (HMI) lesion map was generated by subtracting the reference HMI image from the present HMI peak-to-peak displacement map, as streamed on the computer display. The dimensions of the HMIgFUS lesions were compared against gross pathology. Excellent agreement was found between the lesion depth (r 2  =  0.81, slope  =  0.90), width (r 2  =  0.85, slope  =  1.12) and area (r 2  =  0.58, slope  =  0.75). In vivo feasibility was assessed in a mouse with a pancreatic tumor. These findings demonstrate that HMIgFUS can successfully map thermal lesions and monitor lesion development in real time in vitro and in vivo. The HMIgFUS technique may therefore constitute a novel clinical tool for HIFU treatment monitoring.

Fast lesion mapping during HIFU treatment using harmonic motion imaging guided focused ultrasound (HMIgFUS) in vitro and in vivo.

PubMed

Han, Yang; Wang, Shutao; Payen, Thomas; Konofagou, Elisa

2017-04-21

The successful clinical application of high intensity focused ultrasound (HIFU) ablation depends on reliable monitoring of the lesion formation. Harmonic motion imaging guided focused ultrasound (HMIgFUS) is an ultrasound-based elasticity imaging technique, which monitors HIFU ablation based on the stiffness change of the tissue instead of the echo intensity change in conventional B-mode monitoring, rendering it potentially more sensitive to lesion development. Our group has shown that predicting the lesion location based on the radiation force-excited region is feasible during HMIgFUS. In this study, the feasibility of a fast lesion mapping method is explored to directly monitor the lesion map during HIFU. The harmonic motion imaging (HMI) lesion map was generated by subtracting the reference HMI image from the present HMI peak-to-peak displacement map, as streamed on the computer display. The dimensions of the HMIgFUS lesions were compared against gross pathology. Excellent agreement was found between the lesion depth (r 2   =  0.81, slope  =  0.90), width (r 2   =  0.85, slope  =  1.12) and area (r 2   =  0.58, slope  =  0.75). In vivo feasibility was assessed in a mouse with a pancreatic tumor. These findings demonstrate that HMIgFUS can successfully map thermal lesions and monitor lesion development in real time in vitro and in vivo. The HMIgFUS technique may therefore constitute a novel clinical tool for HIFU treatment monitoring.

Sentinel lymph node biopsy as a prognostic factor in non-metastatic colon cancer: a prospective study.

PubMed

Estrada, O; Pulido, L; Admella, C; Hidalgo, L-A; Clavé, P; Suñol, X

2017-04-01

Around a third of node-negative patients with colon cancer experience a recurrence after surgery, suggesting poor staging. Sentinel lymph node techniques combined with immunochemistry could improve colon cancer staging. We prospectively assessed the effect of Sentinel node mapping on staging and survival in patients with non-metastatic colon cancer. An observational and prospective study was designed. 105 patients with colon cancer were selected. Patients were classified according to node involvement as: N1, with node invasion detected by the conventional techniques; up-staged, with node invasion detected only by sentinel node mapping; and N0, with negative lymph node involvement by both techniques. Five-year survival and disease-free survival rates were analysed. Multivariate regression analyses were performed to identify prognostic factors for disease-free and overall survival. Sentinel node mapping was successfully applied in 78 patients: 33 % were N1; 24.5 % were up-staged (18 patients with isolated tumour cells and 1 patient with micrometastases); and 42.5 % were N0. N1 patients had the poorest overall 5-year survival (65.4 %) and 5-year disease-free survival (69.2 %) rates compared with the other two groups. No significant 5-year survival differences were observed between N0 patients (87.9 %) and up-staged patients (84.2 %). Patients up-staged after sentinel node mapping do not have a poorer prognosis than patients without node involvement. Detection of isolated cancer cells was not a poor prognosis factor in these patients.

The remote sensing of aquatic macrophytes Part 1: Color-infrared aerial photography as a tool for identification and mapping of littoral vegetation. Part 2: Aerial photography as a quantitative tool for the investigation of aquatic ecosystems. [Lake Wingra, Wisconsin

NASA Technical Reports Server (NTRS)

Gustafson, T. D.; Adams, M. S.

1973-01-01

Research was initiated to use aerial photography as an investigative tool in studies that are part of an intensive aquatic ecosystem research effort at Lake Wingra, Madison, Wisconsin. It is anticipated that photographic techniques would supply information about the growth and distribution of littoral macrophytes with efficiency and accuracy greater than conventional methods.

Mapping the spatial distribution and activity of (226)Ra at legacy sites through Machine Learning interpretation of gamma-ray spectrometry data.

PubMed

Varley, Adam; Tyler, Andrew; Smith, Leslie; Dale, Paul; Davies, Mike

2016-03-01

Radium ((226)Ra) contamination derived from military, industrial, and pharmaceutical products can be found at a number of historical sites across the world posing a risk to human health. The analysis of spectral data derived using gamma-ray spectrometry can offer a powerful tool to rapidly estimate and map the activity, depth, and lateral distribution of (226)Ra contamination covering an extensive area. Subsequently, reliable risk assessments can be developed for individual sites in a fraction of the timeframe compared to traditional labour-intensive sampling techniques: for example soil coring. However, local heterogeneity of the natural background, statistical counting uncertainty, and non-linear source response are confounding problems associated with gamma-ray spectral analysis. This is particularly challenging, when attempting to deal with enhanced concentrations of a naturally occurring radionuclide such as (226)Ra. As a result, conventional surveys tend to attribute the highest activities to the largest total signal received by a detector (Gross counts): an assumption that tends to neglect higher activities at depth. To overcome these limitations, a methodology was developed making use of Monte Carlo simulations, Principal Component Analysis and Machine Learning based algorithms to derive depth and activity estimates for (226)Ra contamination. The approach was applied on spectra taken using two gamma-ray detectors (Lanthanum Bromide and Sodium Iodide), with the aim of identifying an optimised combination of detector and spectral processing routine. It was confirmed that, through a combination of Neural Networks and Lanthanum Bromide, the most accurate depth and activity estimates could be found. The advantage of the method was demonstrated by mapping depth and activity estimates at a case study site in Scotland. There the method identified significantly higher activity (<3 Bq g(-1)) occurring at depth (>0.4m), that conventional gross counting algorithms failed to identify. It was concluded that the method could easily be employed to identify areas of high activity potentially occurring at depth, prior to intrusive investigation using conventional sampling techniques. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

Monitoring land cover changes by remote sensing in north west Egypt

NASA Astrophysics Data System (ADS)

Richards, Timothy Steven

The Mediterratiean coastal strip of Egypt is a semi-arid environment which supports a variety of agricultural practices ranging from irrigated sedentary agriculture to semi-nomadic pastoralism. The sedentarisation of the nomadic Bedouin coupled with an increase in population of both people and livestock and a decrease in the extent of the rangelands, has resulted in severe pressure being exerted upon the environment. Satellite remote sensing of vegetation offers the potential to aid regional management by complementing conventional techniques of vegetation mapping and monitoring. This thesis examines the different techniques available for vegetation mapping using visible and near infrared spectral wave bands. The different techniques available for vegetation mapping using remotely sensed data are reviewed and discussed with reference to semi-arid environments. The underlying similarity of many of the techniques is emphasised and their individual merits discussed. The spectral feature-space of Landsat data of two representative study areas in northern Egypt is explored and examined using graphical techniques and principal components analysis. Hand held radiometric field data are also presented for individual soil types within the region. It is proposed that by using reference data for individual soil types, improved estimates of vegetation cover can be ascertained. A number of radiometric corrections are applied to the digital Landsat data in order to convert the arbitrary digital values of the different spectral bands into physical values of reflectance. The effect of this standardization on the principal components is examined. The stratified approach to vegetation mapping which was explored using the field data is applied in turn to the digital Landsat images. Whilst the stratified approach was not found to offer significant advantages over the non-stratified approach in this case, the analysis does serve to provide an accurate datum against which to measure vegetation. In conclusion a satellite based system for operational vegetation monitoring is proposed.

Analyzing mobile WiMAX base station deployment under different frequency planning strategies

NASA Astrophysics Data System (ADS)

Salman, M. K.; Ahmad, R. B.; Ali, Ziad G.; Aldhaibani, Jaafar A.; Fayadh, Rashid A.

2015-05-01

The frequency spectrum is a precious resource and scarce in the communication markets. Therefore, different techniques are adopted to utilize the available spectrum in deploying WiMAX base stations (BS) in cellular networks. In this paper several types of frequency planning techniques are illustrated, and a comprehensive comparative study between conventional frequency reuse of 1 (FR of 1) and fractional frequency reuse (FFR) is presented. These techniques are widely used in network deployment, because they employ universal frequency (using all the available bandwidth) in their base station installation/configuration within network system. This paper presents a network model of 19 base stations in order to be employed in the comparison of the aforesaid frequency planning techniques. Users are randomly distributed within base stations, users' resource mapping and their burst profile selection are based on the measured signal to interference plus-noise ratio (SINR). Simulation results reveal that the FFR has advantages over the conventional FR of 1 in various metrics. 98 % of downlink resources (slots) are exploited when FFR is applied, whilst it is 81 % at FR of 1. Data rate of FFR has been increased to 10.6 Mbps, while it is 7.98 Mbps at FR of 1. The spectral efficiency is better enhanced (1.072 bps/Hz) at FR of 1 than FFR (0.808 bps/Hz), since FR of 1 exploits all the Bandwidth. The subcarrier efficiency shows how many data bits that can be carried by subcarriers under different frequency planning techniques, the system can carry more data bits under FFR (2.40 bit/subcarrier) than FR of 1 (1.998 bit/subcarrier). This study confirms that FFR can perform better than conventional frequency planning (FR of 1) which made it a strong candidate for WiMAX BS deployment in cellular networks.

Mapping of single-copy genes by TSA-FISH in the codling moth, Cydia pomonella.

PubMed

Carabajal Paladino, Leonela Z; Nguyen, Petr; Síchová, Jindra; Marec, František

2014-01-01

We work on the development of transgenic sexing strains in the codling moth, Cydia pomonella (Tortricidae), which would enable to produce male-only progeny for the population control of this pest using sterile insect technique (SIT). To facilitate this research, we have developed a number of cytogenetic and molecular tools, including a physical map of the codling moth Z chromosome using BAC-FISH (fluorescence in situ hybridization with bacterial artificial chromosome probes). However, chromosomal localization of unique, single-copy sequences such as a transgene cassette by conventional FISH remains challenging. In this study, we adapted a FISH protocol with tyramide signal amplification (TSA-FISH) for detection of single-copy genes in Lepidoptera. We tested the protocol with probes prepared from partial sequences of Z-linked genes in the codling moth. Using a modified TSA-FISH protocol we successfully mapped a partial sequence of the Acetylcholinesterase 1 (Ace-1) gene to the Z chromosome and confirmed thus its Z-linkage. A subsequent combination of BAC-FISH with BAC probes containing anticipated neighbouring Z-linked genes and TSA-FISH with the Ace-1 probe allowed the integration of Ace-1 in the physical map of the codling moth Z chromosome. We also developed a two-colour TSA-FISH protocol which enabled us simultaneous localization of two Z-linked genes, Ace-1 and Notch, to the expected regions of the Z chromosome. We showed that TSA-FISH represents a reliable technique for physical mapping of genes on chromosomes of moths and butterflies. Our results suggest that this technique can be combined with BAC-FISH and in the future used for physical localization of transgene cassettes on chromosomes of transgenic lines in the codling moth or other lepidopteran species. Furthermore, the developed protocol for two-colour TSA-FISH might become a powerful tool for synteny mapping in non-model organisms.

Mapping of single-copy genes by TSA-FISH in the codling moth, Cydia pomonella

PubMed Central

2014-01-01

Background We work on the development of transgenic sexing strains in the codling moth, Cydia pomonella (Tortricidae), which would enable to produce male-only progeny for the population control of this pest using sterile insect technique (SIT). To facilitate this research, we have developed a number of cytogenetic and molecular tools, including a physical map of the codling moth Z chromosome using BAC-FISH (fluorescence in situ hybridization with bacterial artificial chromosome probes). However, chromosomal localization of unique, single-copy sequences such as a transgene cassette by conventional FISH remains challenging. In this study, we adapted a FISH protocol with tyramide signal amplification (TSA-FISH) for detection of single-copy genes in Lepidoptera. We tested the protocol with probes prepared from partial sequences of Z-linked genes in the codling moth. Results Using a modified TSA-FISH protocol we successfully mapped a partial sequence of the Acetylcholinesterase 1 (Ace-1) gene to the Z chromosome and confirmed thus its Z-linkage. A subsequent combination of BAC-FISH with BAC probes containing anticipated neighbouring Z-linked genes and TSA-FISH with the Ace-1 probe allowed the integration of Ace-1 in the physical map of the codling moth Z chromosome. We also developed a two-colour TSA-FISH protocol which enabled us simultaneous localization of two Z-linked genes, Ace-1 and Notch, to the expected regions of the Z chromosome. Conclusions We showed that TSA-FISH represents a reliable technique for physical mapping of genes on chromosomes of moths and butterflies. Our results suggest that this technique can be combined with BAC-FISH and in the future used for physical localization of transgene cassettes on chromosomes of transgenic lines in the codling moth or other lepidopteran species. Furthermore, the developed protocol for two-colour TSA-FISH might become a powerful tool for synteny mapping in non-model organisms. PMID:25471491

Application of Extended Kalman Filter in Persistant Scatterer Interferometry to Enhace the Accuracy of Unwrapping Process

NASA Astrophysics Data System (ADS)

Tavakkoli Estahbanat, A.; Dehghani, M.

2017-09-01

In interferometry technique, phases have been modulated between 0-2π. Finding the number of integer phases missed when they were wrapped is the main goal of unwrapping algorithms. Although the density of points in conventional interferometry is high, this is not effective in some cases such as large temporal baselines or noisy interferograms. Due to existing noisy pixels, not only it does not improve results, but also it leads to some unwrapping errors during interferogram unwrapping. In PS technique, because of the sparse PS pixels, scientists are confronted with a problem to unwrap phases. Due to the irregular data separation, conventional methods are sterile. Unwrapping techniques are divided in to path-independent and path-dependent in the case of unwrapping paths. A region-growing method which is a path-dependent technique has been used to unwrap PS data. In this paper an idea of EKF has been generalized on PS data. This algorithm is applied to consider the nonlinearity of PS unwrapping problem as well as conventional unwrapping problem. A pulse-pair method enhanced with singular value decomposition (SVD) has been used to estimate spectral shift from interferometric power spectral density in 7*7 local windows. Furthermore, a hybrid cost-map is used to manage the unwrapping path. This algorithm has been implemented on simulated PS data. To form a sparse dataset, A few points from regular grid are randomly selected and the RMSE of results and true unambiguous phases in presented to validate presented approach. The results of this algorithm and true unwrapped phases were completely identical.

On safe ground? Analysis of European urban geohazards using satellite radar interferometry

NASA Astrophysics Data System (ADS)

Capes, Renalt; Teeuw, Richard

2017-06-01

Urban geological hazards involving ground instability can be costly, dangerous, and affect many people, yet there is little information about the extent or distribution of geohazards within Europe's urban areas. A reason for this is the impracticality of measuring ground instability associated with the many geohazard processes that are often hidden beneath buildings and are imperceptible to conventional geological survey detection techniques. Satellite radar interferometry, or InSAR, offers a remote sensing technique to map mm-scale ground deformation over wide areas given an archive of suitable multi-temporal data. The EC FP7 Space project named PanGeo (2011-2014), used InSAR to map areas of unstable ground in 52 of Europe's cities, representing ∼15% of the EU population. In partnership with Europe's national geological surveys, the PanGeo project developed a standardised geohazard-mapping methodology and recorded 1286 instances of 19 types of geohazard covering 18,000 km2. Presented here is an analysis of the results of the PanGeo-project output data, which provides insights into the distribution of European urban geohazards, their frequency and probability of occurrence. Merging PanGeo data with Eurostat's GeoStat data provides a systematic estimate of population exposures. Satellite radar interferometry is shown to be as a valuable tool for the systematic detection and mapping of urban geohazard phenomena.

Cross-correlation analysis of pulse wave propagation in arteries: in vitro validation and in vivo feasibility

NASA Astrophysics Data System (ADS)

Nauleau, Pierre; Apostolakis, Iason; McGarry, Matthew; Konofagou, Elisa

2018-06-01

The stiffness of the arteries is known to be an indicator of the progression of various cardiovascular diseases. Clinically, the pulse wave velocity (PWV) is used as a surrogate for arterial stiffness. Pulse wave imaging (PWI) is a non-invasive, ultrasound-based imaging technique capable of mapping the motion of the vessel walls, allowing the local assessment of arterial properties. Conventionally, a distinctive feature of the displacement wave (e.g. the 50% upstroke) is tracked across the map to estimate the PWV. However, the presence of reflections, such as those generated at the carotid bifurcation, can bias the PWV estimation. In this paper, we propose a two-step cross-correlation based method to characterize arteries using the information available in the PWI spatio-temporal map. First, the area under the cross-correlation curve is proposed as an index for locating the regions of different properties. Second, a local peak of the cross-correlation function is tracked to obtain a less biased estimate of the PWV. Three series of experiments were conducted in phantoms to evaluate the capabilities of the proposed method compared with the conventional method. In the ideal case of a homogeneous phantom, the two methods performed similarly and correctly estimated the PWV. In the presence of reflections, the proposed method provided a more accurate estimate than conventional processing: e.g. for the soft phantom, biases of  ‑0.27 and ‑0.71 m · s–1 were observed. In a third series of experiments, the correlation-based method was able to locate two regions of different properties with an error smaller than 1 mm. It also provided more accurate PWV estimates than conventional processing (biases:  ‑0.12 versus ‑0.26 m · s–1). Finally, the in vivo feasibility of the proposed method was demonstrated in eleven healthy subjects. The results indicate that the correlation-based method might be less precise in vivo but more accurate than the conventional method.

Monitoring of thermal therapy based on shear modulus changes: I. shear wave thermometry.

PubMed

Arnal, Bastien; Pernot, Mathieu; Tanter, Mickael

2011-02-01

The clinical applicability of high-intensity focused ultrasound (HIFU) for noninvasive therapy is today hampered by the lack of robust and real-time monitoring of tissue damage during treatment. The goal of this study is to show that the estimation of local tissue elasticity from shear wave imaging (SWI) can lead to the 2-D mapping of temperature changes during HIFU treatments. This new concept of shear wave thermometry is experimentally implemented here using conventional ultrasonic imaging probes. HIFU treatment and monitoring were, respectively, performed using a confocal setup consisting of a 2.5-MHz single-element transducer focused at 30 mm on ex vivo samples and an 8-MHz ultrasound diagnostic probe. Thermocouple measurements and ultrasound-based thermometry were used as a gold standard technique and were combined with SWI on the same device. The SWI sequences consisted of 2 successive shear waves induced at different lateral positions. Each wave was created using 100-μs pushing beams at 3 depths. The shear wave propagation was acquired at 17,000 frames/s, from which the elasticity map was recovered. HIFU sonications were interleaved with fast imaging acquisitions, allowing a duty cycle of more than 90%. Elasticity and temperature mapping was achieved every 3 s, leading to realtime monitoring of the treatment. Tissue stiffness was found to decrease in the focal zone for temperatures up to 43°C. Ultrasound-based temperature estimation was highly correlated to stiffness variation maps (r² = 0.91 to 0.97). A reversible calibration phase of the changes of elasticity with temperature can be made locally using sighting shots. This calibration process allows for the derivation of temperature maps from shear wave imaging. Compared with conventional ultrasound-based approaches, shear wave thermometry is found to be much more robust to motion artifacts.

High-resolution whole-brain DCE-MRI using constrained reconstruction: Prospective clinical evaluation in brain tumor patients.

PubMed

Guo, Yi; Lebel, R Marc; Zhu, Yinghua; Lingala, Sajan Goud; Shiroishi, Mark S; Law, Meng; Nayak, Krishna

2016-05-01

To clinically evaluate a highly accelerated T1-weighted dynamic contrast-enhanced (DCE) MRI technique that provides high spatial resolution and whole-brain coverage via undersampling and constrained reconstruction with multiple sparsity constraints. Conventional (rate-2 SENSE) and experimental DCE-MRI (rate-30) scans were performed 20 minutes apart in 15 brain tumor patients. The conventional clinical DCE-MRI had voxel dimensions 0.9 × 1.3 × 7.0 mm(3), FOV 22 × 22 × 4.2 cm(3), and the experimental DCE-MRI had voxel dimensions 0.9 × 0.9 × 1.9 mm(3), and broader coverage 22 × 22 × 19 cm(3). Temporal resolution was 5 s for both protocols. Time-resolved images and blood-brain barrier permeability maps were qualitatively evaluated by two radiologists. The experimental DCE-MRI scans showed no loss of qualitative information in any of the cases, while achieving substantially higher spatial resolution and whole-brain spatial coverage. Average qualitative scores (from 0 to 3) were 2.1 for the experimental scans and 1.1 for the conventional clinical scans. The proposed DCE-MRI approach provides clinically superior image quality with higher spatial resolution and coverage than currently available approaches. These advantages may allow comprehensive permeability mapping in the brain, which is especially valuable in the setting of large lesions or multiple lesions spread throughout the brain.

Measurements for the BETC in-situ combustion experiment. [Post test surveys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wayland, J.R.; Bartel, L.C.

The Bartlesville Energy Technology Center (BETC) in situ combustion pilot project near Bartlette, Kansas, was studied using controlled source audio-magnetotelluric (CSAMT) mapping, thermal gravimetric analysis (TGA), conventional geophysical logging and modeling of the fireflood. Measurements of formation resistivity changes induced by in situ combustion indicate that CSAMT resistivity maps should show an increase in apparent resistivity. The substantial decrease of apparent resistivity measured within the five spot pattern indicated a complex sequence of events. Using the results from the CSAMT surveys the fire front was located and posttest core samples were obtained. The posttest core samples were examined using TGAmore » techniques, and using information from combustion tube runs as standards, the location of the fire front in the core samples from the posttest holes was inferred. Models of the reservoir in situ combustion process were developed to help analyze the field results. The combustion kinematics, when used in conjunction with CSAMT and TGA techniques, indicated that considerable bypass of injected air occurred with an influx of brine into previously burned zones. This experiment offered an opportunity to integrate several new techniques into a systematic study of a difficult problem.« less

Visualization Case Study: Eyjafjallajökull Ash (Invited)

NASA Astrophysics Data System (ADS)

Simmon, R.

2010-12-01

Although data visualization is a powerful tool in Earth science, the resulting imagery is often complex and difficult to interpret for non-experts. Students, journalists, web site visitors, or museum attendees often have difficulty understanding some of the imagery scientists create, particularly false-color imagery and data-driven maps. Many visualizations are designed for data exploration or peer communication, and often follow discipline conventions or are constrained by software defaults. Different techniques are necessary for communication with a broad audience. Data visualization combines ideas from cognitive science, graphic design, and cartography, and applies them to the challenge of presenting data clearly. Visualizers at NASA's Earth Observatory web site (earthobservatory.nasa.gov) use these techniques to craft remote sensing imagery for interested but non-expert readers. Images range from natural-color satellite images and multivariate maps to illustrations of abstract concepts. I will use imagery of the eruption of Iceland's Eyjafjallajökull volcano as a case study, showing specific applications of general design techniques. By using color carefully (including contextual data), precisely aligning disparate data sets, and highlighting important features, we crafted an image that clearly conveys the complex vertical and horizontal distribution of airborne ash.

PLASMAP: an interactive computational tool for storage, retrieval and device-independent graphic display of conventional restriction maps.

PubMed Central

Stone, B N; Griesinger, G L; Modelevsky, J L

1984-01-01

We describe an interactive computational tool, PLASMAP, which allows the user to electronically store, retrieve, and display circular restriction maps. PLASMAP permits users to construct libraries of plasmid restriction maps as a set of files which may be edited in the laboratory at any time. The display feature of PLASMAP quickly generates device-independent, artist-quality, full-color or monochrome, hard copies or CRT screens of complex, conventional circular restriction maps. PMID:6320096

Diffusion kurtosis imaging of the liver at 3 Tesla: in vivo comparison to standard diffusion-weighted imaging.

PubMed

Budjan, Johannes; Sauter, Elke A; Zoellner, Frank G; Lemke, Andreas; Wambsganss, Jens; Schoenberg, Stefan O; Attenberger, Ulrike I

2018-01-01

Background Functional techniques like diffusion-weighted imaging (DWI) are gaining more and more importance in liver magnetic resonance imaging (MRI). Diffusion kurtosis imaging (DKI) is an advanced technique that might help to overcome current limitations of DWI. Purpose To evaluate DKI for the differentiation of hepatic lesions in comparison to conventional DWI at 3 Tesla. Material and Methods Fifty-six consecutive patients were examined using a routine abdominal MR protocol at 3 Tesla which included DWI with b-values of 50, 400, 800, and 1000 s/mm 2 . Apparent diffusion coefficient maps were calculated applying a standard mono-exponential fit, while a non-Gaussian kurtosis fit was used to obtain DKI maps. ADC as well as Kurtosis-corrected diffusion ( D) values were quantified by region of interest analysis and compared between lesions. Results Sixty-eight hepatic lesions (hepatocellular carcinoma [HCC] [n = 25]; hepatic adenoma [n = 4], cysts [n = 18]; hepatic hemangioma [HH] [n = 18]; and focal nodular hyperplasia [n = 3]) were identified. Differentiation of malignant and benign lesions was possible based on both DWI ADC as well as DKI D-values ( P values were in the range of 0.04 to < 0.0001). Conclusion In vivo abdominal DKI calculated using standard b-values is feasible and enables quantitative differentiation between malignant and benign liver lesions. Assessment of conventional ADC values leads to similar results when using b-values below 1000 s/mm 2 for DKI calculation.

Q-ball imaging with PROPELLER EPI acquisition.

PubMed

Chou, Ming-Chung; Huang, Teng-Yi; Chung, Hsiao-Wen; Hsieh, Tsyh-Jyi; Chang, Hing-Chiu; Chen, Cheng-Yu

2013-12-01

Q-ball imaging (QBI) is an imaging technique that is capable of resolving intravoxel fiber crossings; however, the signal readout based on echo-planar imaging (EPI) introduces geometric distortions in the presence of susceptibility gradients. This study proposes an imaging technique that reduces susceptibility distortions in QBI by short-axis PROPELLER EPI acquisition. Conventional QBI and PROPELLER QBI data were acquired from two 3T MR scans of the brains of five healthy subjects. Prior to the PROPELLER reconstruction, residual distortions in single-blade low-resolution b0 and diffusion-weighted images (DWIs) were minimized by linear affine and nonlinear diffeomorphic demon registrations. Subsequently, the PROPELLER keyhole reconstruction was applied to the corrected DWIs to obtain high-resolution PROPELLER DWIs. The generalized fractional anisotropy and orientation distribution function maps contained fewer distortions in PROPELLER QBI than in conventional QBI, and the fiber tracts more closely matched the brain anatomy depicted by turbo spin-echo (TSE) T2-weighted imaging (T2WI). Furthermore, for fixed T(E), PROPELLER QBI enabled a shorter scan time than conventional QBI. We conclude that PROPELLER QBI can reduce susceptibility distortions without lengthening the acquisition time and is suitable for tracing neuronal fiber tracts in the human brain. Copyright © 2013 John Wiley & Sons, Ltd.

Left ventricular hypertrophy: The relationship between the electrocardiogram and cardiovascular magnetic resonance imaging.

PubMed

Bacharova, Ljuba; Ugander, Martin

2014-11-01

Conventional assessment of left ventricular hypertrophy (LVH) using the electrocardiogram (ECG), for example, by the Sokolow-Lyon, Romhilt-Estes or Cornell criteria, have relied on assessing changes in the amplitude and/or duration of the QRS complex of the ECG to quantify LV mass. ECG measures of LV mass have typically been validated by imaging with echocardiography or cardiovascular magnetic resonance imaging (CMR). However, LVH can be the result of diverse etiologies, and LVH is also characterized by pathological changes in myocardial tissue characteristics on the genetic, molecular, cellular, and tissue level beyond a pure increase in the number of otherwise normal cardiomyocytes. For example, slowed conduction velocity through the myocardium, which can be due to diffuse myocardial fibrosis, has been shown to be an important determinant of conventional ECG LVH criteria regardless of LV mass. Myocardial tissue characterization by CMR has emerged to not only quantify LV mass, but also detect and quantify the extent and severity of focal or diffuse myocardial fibrosis, edema, inflammation, myocarditis, fatty replacement, myocardial disarray, and myocardial deposition of amyloid proteins (amyloidosis), glycolipids (Fabry disease), or iron (siderosis). This can be undertaken using CMR techniques including late gadolinium enhancement (LGE), T1 mapping, T2 mapping, T2* mapping, extracellular volume fraction (ECV) mapping, fat/water-weighted imaging, and diffusion tensor CMR. This review presents an overview of current and emerging concepts regarding the diagnostic possibilities of both ECG and CMR for LVH in an attempt to narrow gaps in our knowledge regarding the ECG diagnosis of LVH. © 2014 Wiley Periodicals, Inc.

Dense range map reconstruction from a versatile robotic sensor system with an active trinocular vision and a passive binocular vision.

PubMed

Kim, Min Young; Lee, Hyunkee; Cho, Hyungsuck

2008-04-10

One major research issue associated with 3D perception by robotic systems is the creation of efficient sensor systems that can generate dense range maps reliably. A visual sensor system for robotic applications is developed that is inherently equipped with two types of sensor, an active trinocular vision and a passive stereo vision. Unlike in conventional active vision systems that use a large number of images with variations of projected patterns for dense range map acquisition or from conventional passive vision systems that work well on specific environments with sufficient feature information, a cooperative bidirectional sensor fusion method for this visual sensor system enables us to acquire a reliable dense range map using active and passive information simultaneously. The fusion algorithms are composed of two parts, one in which the passive stereo vision helps active vision and the other in which the active trinocular vision helps the passive one. The first part matches the laser patterns in stereo laser images with the help of intensity images; the second part utilizes an information fusion technique using the dynamic programming method in which image regions between laser patterns are matched pixel-by-pixel with help of the fusion results obtained in the first part. To determine how the proposed sensor system and fusion algorithms can work in real applications, the sensor system is implemented on a robotic system, and the proposed algorithms are applied. A series of experimental tests is performed for a variety of configurations of robot and environments. The performance of the sensor system is discussed in detail.

Analysis of painted arts by energy sensitive radiographic techniques with the Pixel Detector Timepix

NASA Astrophysics Data System (ADS)

Zemlicka, J.; Jakubek, J.; Kroupa, M.; Hradil, D.; Hradilova, J.; Mislerova, H.

2011-01-01

Non-invasive techniques utilizing X-ray radiation offer a significant advantage in scientific investigations of painted arts and other cultural artefacts such as painted artworks or statues. In addition, there is also great demand for a mobile analytical and real-time imaging device given the fact that many fine arts cannot be transported. The highly sensitive hybrid semiconductor pixel detector, Timepix, is capable of detecting and resolving subtle and low-contrast differences in the inner composition of a wide variety of objects. Moreover, it is able to map the surface distribution of the contained elements. Several transmission and emission techniques are presented which have been proposed and tested for the analysis of painted artworks. This study focuses on the novel techniques of X-ray transmission radiography (conventional and energy sensitive) and X-ray induced fluorescence imaging (XRF) which can be realised at the table-top scale with the state-of-the-art pixel detector Timepix. Transmission radiography analyses the changes in the X-ray beam intensity caused by specific attenuation of different components in the sample. The conventional approach uses all energies from the source spectrum for the creation of the image while the energy sensitive alternative creates images in given energy intervals which enable identification and separation of materials. The XRF setup is based on the detection of characteristic radiation induced by X-ray photons through a pinhole geometry collimator. The XRF method is extremely sensitive to the material composition but it creates only surface maps of the elemental distribution. For the purpose of the analysis several sets of painted layers have been prepared in a restoration laboratory. The composition of these layers corresponds to those of real historical paintings from the 19th century. An overview of the current status of our methods will be given with respect to the instrumentation and the application in the field of cultural heritage.

Reducing surgical levels by paraspinal mapping and diffusion tensor imaging techniques in lumbar spinal stenosis.

PubMed

Chen, Hua-Biao; Wan, Qi; Xu, Qi-Feng; Chen, Yi; Bai, Bo

2016-04-25

Correlating symptoms and physical examination findings with surgical levels based on common imaging results is not reliable. In patients who have no concordance between radiological and clinical symptoms, the surgical levels determined by conventional magnetic resonance imaging (MRI) and neurogenic examination (NE) may lead to a more extensive surgery and significant complications. We aimed to confirm that whether the use of diffusion tensor imaging (DTI) and paraspinal mapping (PM) techniques can further prevent the occurrence of false positives with conventional MRI, distinguish which are clinically relevant from levels of cauda equina and/or nerve root lesions based on MRI, and determine and reduce the decompression levels of lumbar spinal stenosis than MRI + NE, while ensuring or improving surgical outcomes. We compared the data between patients who underwent MRI + (PM or DTI) and patients who underwent conventional MRI + NE to determine levels of decompression for the treatment of lumbar spinal stenosis. Outcome measures were assessed at 2 weeks, 3 months, 6 months, and 12 months postoperatively. One hundred fourteen patients (59 in the control group, 54 in the experimental group) underwent decompression. The levels of decompression determined by MRI + (PM or DTI) in the experimental group were significantly less than that determined by MRI + NE in the control group (p = 0.000). The surgical time, blood loss, and surgical transfusion were significantly less in the experimental group (p = 0.001, p = 0.011, p = 0.001, respectively). There were no differences in improvement of the visual analog scale back and leg pain (VAS-BP, VAS-LP) scores and Oswestry Disability Index (ODI) scores at 2 weeks, 3 months, 6 months, and 12 months after operation between the experimental and control groups. MRI + (PM or DTI) showed clear benefits in determining decompression levels of lumbar spinal stenosis than MRI + NE. In patients with lumbar spinal stenosis, the use of PM and DTI techniques reduces decompression levels and increases safety and benefits of surgery.

BoreholeAR: A mobile tablet application for effective borehole database visualization using an augmented reality technology

NASA Astrophysics Data System (ADS)

Lee, Sangho; Suh, Jangwon; Park, Hyeong-Dong

2015-03-01

Boring logs are widely used in geological field studies since the data describes various attributes of underground and surface environments. However, it is difficult to manage multiple boring logs in the field as the conventional management and visualization methods are not suitable for integrating and combining large data sets. We developed an iPad application to enable its user to search the boring log rapidly and visualize them using the augmented reality (AR) technique. For the development of the application, a standard borehole database appropriate for a mobile-based borehole database management system was designed. The application consists of three modules: an AR module, a map module, and a database module. The AR module superimposes borehole data on camera imagery as viewed by the user and provides intuitive visualization of borehole locations. The map module shows the locations of corresponding borehole data on a 2D map with additional map layers. The database module provides data management functions for large borehole databases for other modules. Field survey was also carried out using more than 100,000 borehole data.

Snow survey and vegetation growth in high mountains (Swiss Alps)

NASA Technical Reports Server (NTRS)

Haefner, H. (Principal Investigator)

1973-01-01

The author has identified the following significant results. A method for mapping snow over large areas was developed combining the possibilities of a Quantimet (QTM 72) to evaluate the exact density level of the snow cover for each individual image (or a selected section of the photo) with the higher resolution of photographic techniques. The density level established on the monitor by visual control is used as reference for the exposure time of a lithographic film, producing a clear tonal separation of all snow- and ice-covered areas from uncovered land in black and white. The data is projected onto special maps 1:500,000 or 1:100,000 showing the contour lines and the hydrographic features only. The areal extent of the snow cover may be calculated directly with the QTM 720 or on the map. Bands 4 and 5 provide the most accurate results for mapping snow. Using all four bands a separation of an old melting snow cover from a new one is possible. Regional meteorological studies combining ERTS-1 imagery and conventional sources describe synoptical evolution of meteorological systems over the Alps.

Novel method for measuring a dense 3D strain map of robotic flapping wings

NASA Astrophysics Data System (ADS)

Li, Beiwen; Zhang, Song

2018-04-01

Measuring dense 3D strain maps of the inextensible membranous flapping wings of robots is of vital importance to the field of bio-inspired engineering. Conventional high-speed 3D videography methods typically reconstruct the wing geometries through measuring sparse points with fiducial markers, and thus cannot obtain the full-field mechanics of the wings in detail. In this research, we propose a novel system to measure a dense strain map of inextensible membranous flapping wings by developing a superfast 3D imaging system and a computational framework for strain analysis. Specifically, first we developed a 5000 Hz 3D imaging system based on the digital fringe projection technique using the defocused binary patterns to precisely measure the dynamic 3D geometries of rapidly flapping wings. Then, we developed a geometry-based algorithm to perform point tracking on the precisely measured 3D surface data. Finally, we developed a dense strain computational method using the Kirchhoff-Love shell theory. Experiments demonstrate that our method can effectively perform point tracking and measure a highly dense strain map of the wings without many fiducial markers.

ACCELERATING MR PARAMETER MAPPING USING SPARSITY-PROMOTING REGULARIZATION IN PARAMETRIC DIMENSION

PubMed Central

Velikina, Julia V.; Alexander, Andrew L.; Samsonov, Alexey

2013-01-01

MR parameter mapping requires sampling along additional (parametric) dimension, which often limits its clinical appeal due to a several-fold increase in scan times compared to conventional anatomic imaging. Data undersampling combined with parallel imaging is an attractive way to reduce scan time in such applications. However, inherent SNR penalties of parallel MRI due to noise amplification often limit its utility even at moderate acceleration factors, requiring regularization by prior knowledge. In this work, we propose a novel regularization strategy, which utilizes smoothness of signal evolution in the parametric dimension within compressed sensing framework (p-CS) to provide accurate and precise estimation of parametric maps from undersampled data. The performance of the method was demonstrated with variable flip angle T1 mapping and compared favorably to two representative reconstruction approaches, image space-based total variation regularization and an analytical model-based reconstruction. The proposed p-CS regularization was found to provide efficient suppression of noise amplification and preservation of parameter mapping accuracy without explicit utilization of analytical signal models. The developed method may facilitate acceleration of quantitative MRI techniques that are not suitable to model-based reconstruction because of complex signal models or when signal deviations from the expected analytical model exist. PMID:23213053

Palaeogeographic reconstruction of sandstones using weighted mean grain-size maps, with examples from the Karoo Basin (South Africa) and the Sydney Basin (Australia)

NASA Astrophysics Data System (ADS)

le Roux, J. P.

1992-12-01

Although sandstone grain-size maps can be a powerful means of reconstructing ancient depositional environments, they have rarely been used in the past. In this paper, two case studies are presented to illustrate the potential of this technique where other, more conventional methods may not be applicable. In the first case, a braided to anastomosing river system in the Triassic Molteno Formation of the South African Karoo Basin is examined. The weighted mean grain-size map clearly portrays the distribution of channels and islands and compares very well with other methods of reconstruction. The second case study examines an offshore shoal in the Permian Nowra Sandstone of the Sydney Basin in Australia. Here the grain-size map shows a north-northeasterly trend parallel to the orientation of the shoal, with a zone of coarsest grains displaced to the east of the shoal crest. This probably reflects the location of the breaker zone. As grain size is an important factor controlling the porosity and permeability of sediments, these maps can provide very useful information when exploring for epigenetic, stratabound ore deposits such as uranium, or planning production wells for oil and gas.

A novel algorithm for thermal image encryption.

PubMed

Hussain, Iqtadar; Anees, Amir; Algarni, Abdulmohsen

2018-04-16

Thermal images play a vital character at nuclear plants, Power stations, Forensic labs biological research, and petroleum products extraction. Safety of thermal images is very important. Image data has some unique features such as intensity, contrast, homogeneity, entropy and correlation among pixels that is why somehow image encryption is trickier as compare to other encryptions. With conventional image encryption schemes it is normally hard to handle these features. Therefore, cryptographers have paid attention to some attractive properties of the chaotic maps such as randomness and sensitivity to build up novel cryptosystems. That is why, recently proposed image encryption techniques progressively more depends on the application of chaotic maps. This paper proposed an image encryption algorithm based on Chebyshev chaotic map and S8 Symmetric group of permutation based substitution boxes. Primarily, parameters of chaotic Chebyshev map are chosen as a secret key to mystify the primary image. Then, the plaintext image is encrypted by the method generated from the substitution boxes and Chebyshev map. By this process, we can get a cipher text image that is perfectly twisted and dispersed. The outcomes of renowned experiments, key sensitivity tests and statistical analysis confirm that the proposed algorithm offers a safe and efficient approach for real-time image encryption.

Modeling and comparative study of fluid velocities in heterogeneous rocks

NASA Astrophysics Data System (ADS)

Hingerl, Ferdinand F.; Romanenko, Konstantin; Pini, Ronny; Balcom, Bruce; Benson, Sally

2013-04-01

Detailed knowledge of the distribution of effective porosity and fluid velocities in heterogeneous rock samples is crucial for understanding and predicting spatially resolved fluid residence times and kinetic reaction rates of fluid-rock interactions. The applicability of conventional MRI techniques to sedimentary rocks is limited by internal magnetic field gradients and short spin relaxation times. The approach developed at the UNB MRI Centre combines the 13-interval Alternating-Pulsed-Gradient Stimulated-Echo (APGSTE) scheme and three-dimensional Single Point Ramped Imaging with T1 Enhancement (SPRITE). These methods were designed to reduce the errors due to effects of background gradients and fast transverse relaxation. SPRITE is largely immune to time-evolution effects resulting from background gradients, paramagnetic impurities and chemical shift. Using these techniques quantitative 3D porosity maps as well as single-phase fluid velocity fields in sandstone core samples were measured. Using a new Magnetic Resonance Imaging technique developed at the MRI Centre at UNB, we created 3D maps of porosity distributions as well as single-phase fluid velocity distributions of sandstone rock samples. Then, we evaluated the applicability of the Kozeny-Carman relationship for modeling measured fluid velocity distributions in sandstones samples showing meso-scale heterogeneities using two different modeling approaches. The MRI maps were used as reference points for the modeling approaches. For the first modeling approach, we applied the Kozeny-Carman relationship to the porosity distributions and computed respective permeability maps, which in turn provided input for a CFD simulation - using the Stanford CFD code GPRS - to compute averaged velocity maps. The latter were then compared to the measured velocity maps. For the second approach, the measured velocity distributions were used as input for inversely computing permeabilities using the GPRS CFD code. The computed permeabilities were then correlated with the ones based on the porosity maps and the Kozeny-Carman relationship. The findings of the comparative modeling study are discussed and its potential impact on the modeling of fluid residence times and kinetic reaction rates of fluid-rock interactions in rocks containing meso-scale heterogeneities are reviewed.

Fit of lithium disilicate crowns fabricated from conventional and digital impressions assessed with micro-CT.

PubMed

Kim, Jae-Hyun; Jeong, Ji-Hye; Lee, Jin-Han; Cho, Hye-Won

2016-10-01

Although the number of lithium disilicate crowns fabricated with computer-aided design and computer-aided manufacturing (CAD-CAM) technology has increased, the accuracy of the prostheses produced by using digital pathways remains unknown. The purpose of this in vitro study was to compare marginal and internal discrepancies of lithium disilicate crowns fabricated from digital and conventional impressions. A typodont mandibular first molar was prepared for a lithium disilicate crown, and 20 duplicate dies were fabricated by milling poly(methyl methacrylate) resin blocks from laboratory scans. Four groups of 5 lithium disilicate crowns each were created by using a CS3500 (Carestream Dental) intraoral digital impression; Trios (3shape) intraoral digital impression; Ceramill Map400 (Amann Girrbach) extraoral digital impression; and a heat-press technique as a control group. All of the IPS e.max CAD (Ivoclar Vivadent AG) crowns were produced using a 5-axis milling engine (Ceramill Motion2). The lithium disilicate crowns were cemented with zinc phosphate cement under finger pressure. Marginal and internal discrepancies were measured using micro-computed tomography (SkyScan1172). One-way ANOVAs with the Tukey honest significant differences test were used for statistical analysis of the data (α=.05). The mean marginal discrepancies of CS3500 lithium disilicate crowns were 129.6 μm, 200.9 μm for Ceramill Map400, and 207.8 μm 176.1 μm for the heat-press technique; and the internal discrepancy volumes for CS3500 were 25.3 mm 3 , 40.7 mm 3 for Trios, 29.1 mm 3 for Ceramill Map400, and 29.1 and 31.4 mm 3 for the heat-press technique. The CS3500 group showed a significantly better marginal discrepancy than the other 3 groups and a smaller internal discrepancy volume than the Trios group (P<.05). Significant differences were found between IPS e.max CAD crowns produced using 2 intraoral digital impressions, whereas no differences were found between IPS e.max CAD crowns produced from an extraoral digital impression and IPS e.max Press crowns produced using a heat-press technique. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

Motion planning with complete knowledge using a colored SOM.

PubMed

Vleugels, J; Kok, J N; Overmars, M

1997-01-01

The motion planning problem requires that a collision-free path be determined for a robot moving amidst a fixed set of obstacles. Most neural network approaches to this problem are for the situation in which only local knowledge about the configuration space is available. The main goal of the paper is to show that neural networks are also suitable tools in situations with complete knowledge of the configuration space. In this paper we present an approach that combines a neural network and deterministic techniques. We define a colored version of Kohonen's self-organizing map that consists of two different classes of nodes. The network is presented with random configurations of the robot and, from this information, it constructs a road map of possible motions in the work space. The map is a growing network, and different nodes are used to approximate boundaries of obstacles and the Voronoi diagram of the obstacles, respectively. In a second phase, the positions of the two kinds of nodes are combined to obtain the road map. In this way a number of typical problems with small obstacles and passages are avoided, and the required number of nodes for a given accuracy is within reasonable limits. This road map is searched to find a motion connecting the given source and goal configurations of the robot. The algorithm is simple and general; the only specific computation that is required is a check for intersection of two polygons. We implemented the algorithm for planar robots allowing both translation and rotation and experiments show that compared to conventional techniques it performs well, even for difficult motion planning scenes.

High-resolution x-ray absorption spectroscopy studies of metal compounds in neurodegenerative brain tissue

NASA Astrophysics Data System (ADS)

Collingwood, J. F.; Mikhaylova, A.; Davidson, M. R.; Batich, C.; Streit, W. J.; Eskin, T.; Terry, J.; Barrea, R.; Underhill, R. S.; Dobson, J.

2005-01-01

Fluorescence mapping and microfocus X-ray absorption spectroscopy are used to detect, locate and identify iron biominerals and other inorganic metal accumulations in neurodegenerative brain tissue at sub-cellular resolution (<5 microns). Recent progress in developing the technique is reviewed. Synchrotron X-rays are used to map tissue sections for metals of interest, and XANES and XAFS are used to characterise anomalous concentrations of the metals in-situ so that they can be correlated with tissue structures and disease pathology. Iron anomalies associated with biogenic magnetite, ferritin and haemoglobin are located and identified in an avian tissue model with a pixel resolution ~5 microns. Subsequent studies include brain tissue sections from transgenic Huntington's mice, and the first high-resolution mapping and identification of iron biominerals in human Alzheimer's and control autopsy brain tissue. Technical developments include use of microfocus diffraction to obtain structural information about biominerals in-situ, and depositing sample location grids by lithography for the location of anomalies by conventional microscopy. The combined techniques provide a breakthrough in the study of both intra- and extra-cellular iron compounds and related metals in tissue. The information to be gained from this approach has implications for future diagnosis and treatment of neurodegeneration, and for our understanding of the mechanisms involved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Sang Beom; Dsilva, Carmeline J.; Debenedetti, Pablo G., E-mail: pdebene@princeton.edu

Understanding the mechanisms by which proteins fold from disordered amino-acid chains to spatially ordered structures remains an area of active inquiry. Molecular simulations can provide atomistic details of the folding dynamics which complement experimental findings. Conventional order parameters, such as root-mean-square deviation and radius of gyration, provide structural information but fail to capture the underlying dynamics of the protein folding process. It is therefore advantageous to adopt a method that can systematically analyze simulation data to extract relevant structural as well as dynamical information. The nonlinear dimensionality reduction technique known as diffusion maps automatically embeds the high-dimensional folding trajectories inmore » a lower-dimensional space from which one can more easily visualize folding pathways, assuming the data lie approximately on a lower-dimensional manifold. The eigenvectors that parametrize the low-dimensional space, furthermore, are determined systematically, rather than chosen heuristically, as is done with phenomenological order parameters. We demonstrate that diffusion maps can effectively characterize the folding process of a Trp-cage miniprotein. By embedding molecular dynamics simulation trajectories of Trp-cage folding in diffusion maps space, we identify two folding pathways and intermediate structures that are consistent with the previous studies, demonstrating that this technique can be employed as an effective way of analyzing and constructing protein folding pathways from molecular simulations.« less

On Voxel based Iso-Tumor Control Probabilty and Iso-Complication Maps for Selective Boosting and Selective Avoidance Intensity Modulated Radiotherapy.

PubMed

Kim, Yusung; Tomé, Wolfgang A

2008-01-01

Voxel based iso-Tumor Control Probability (TCP) maps and iso-Complication maps are proposed as a plan-review tool especially for functional image-guided intensity-modulated radiotherapy (IMRT) strategies such as selective boosting (dose painting) and conformal avoidance IMRT. The maps employ voxel-based phenomenological biological dose-response models for target volumes and normal organs. Two IMRT strategies for prostate cancer, namely conventional uniform IMRT delivering an EUD = 84 Gy (equivalent uniform dose) to the entire PTV and selective boosting delivering an EUD = 82 Gy to the entire PTV, are investigated, to illustrate the advantages of this approach over iso-dose maps. Conventional uniform IMRT did yield a more uniform isodose map to the entire PTV while selective boosting did result in a nonuniform isodose map. However, when employing voxel based iso-TCP maps selective boosting exhibited a more uniform tumor control probability map compared to what could be achieved using conventional uniform IMRT, which showed TCP cold spots in high-risk tumor subvolumes despite delivering a higher EUD to the entire PTV. Voxel based iso-Complication maps are presented for rectum and bladder, and their utilization for selective avoidance IMRT strategies are discussed. We believe as the need for functional image guided treatment planning grows, voxel based iso-TCP and iso-Complication maps will become an important tool to assess the integrity of such treatment plans.

Automated mapping of persistent ice and snow cover across the western U.S. with Landsat

NASA Astrophysics Data System (ADS)

Selkowitz, David J.; Forster, Richard R.

2016-07-01

We implemented an automated approach for mapping persistent ice and snow cover (PISC) across the conterminous western U.S. using all available Landsat TM and ETM+ scenes acquired during the late summer/early fall period between 2010 and 2014. Two separate validation approaches indicate this dataset provides a more accurate representation of glacial ice and perennial snow cover for the region than either the U.S. glacier database derived from US Geological Survey (USGS) Digital Raster Graphics (DRG) maps (based on aerial photography primarily from the 1960s-1980s) or the National Land Cover Database 2011 perennial ice and snow cover class. Our 2010-2014 Landsat-derived dataset indicates 28% less glacier and perennial snow cover than the USGS DRG dataset. There are larger differences between the datasets in some regions, such as the Rocky Mountains of Northwest Wyoming and Southwest Montana, where the Landsat dataset indicates 54% less PISC area. Analysis of Landsat scenes from 1987-1988 and 2008-2010 for three regions using a more conventional, semi-automated approach indicates substantial decreases in glaciers and perennial snow cover that correlate with differences between PISC mapped by the USGS DRG dataset and the automated Landsat-derived dataset. This suggests that most of the differences in PISC between the USGS DRG and the Landsat-derived dataset can be attributed to decreases in PISC, as opposed to differences between mapping techniques. While the dataset produced by the automated Landsat mapping approach is not designed to serve as a conventional glacier inventory that provides glacier outlines and attribute information, it allows for an updated estimate of PISC for the conterminous U.S. as well as for smaller regions. Additionally, the new dataset highlights areas where decreases in PISC have been most significant over the past 25-50 years.

Automated mapping of persistent ice and snow cover across the western U.S. with Landsat

USGS Publications Warehouse

Selkowitz, David J.; Forster, Richard R.

2016-01-01

We implemented an automated approach for mapping persistent ice and snow cover (PISC) across the conterminous western U.S. using all available Landsat TM and ETM+ scenes acquired during the late summer/early fall period between 2010 and 2014. Two separate validation approaches indicate this dataset provides a more accurate representation of glacial ice and perennial snow cover for the region than either the U.S. glacier database derived from US Geological Survey (USGS) Digital Raster Graphics (DRG) maps (based on aerial photography primarily from the 1960s–1980s) or the National Land Cover Database 2011 perennial ice and snow cover class. Our 2010–2014 Landsat-derived dataset indicates 28% less glacier and perennial snow cover than the USGS DRG dataset. There are larger differences between the datasets in some regions, such as the Rocky Mountains of Northwest Wyoming and Southwest Montana, where the Landsat dataset indicates 54% less PISC area. Analysis of Landsat scenes from 1987–1988 and 2008–2010 for three regions using a more conventional, semi-automated approach indicates substantial decreases in glaciers and perennial snow cover that correlate with differences between PISC mapped by the USGS DRG dataset and the automated Landsat-derived dataset. This suggests that most of the differences in PISC between the USGS DRG and the Landsat-derived dataset can be attributed to decreases in PISC, as opposed to differences between mapping techniques. While the dataset produced by the automated Landsat mapping approach is not designed to serve as a conventional glacier inventory that provides glacier outlines and attribute information, it allows for an updated estimate of PISC for the conterminous U.S. as well as for smaller regions. Additionally, the new dataset highlights areas where decreases in PISC have been most significant over the past 25–50 years.

RAY-RAMSES: a code for ray tracing on the fly in N-body simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barreira, Alexandre; Llinares, Claudio; Bose, Sownak

2016-05-01

We present a ray tracing code to compute integrated cosmological observables on the fly in AMR N-body simulations. Unlike conventional ray tracing techniques, our code takes full advantage of the time and spatial resolution attained by the N-body simulation by computing the integrals along the line of sight on a cell-by-cell basis through the AMR simulation grid. Moroever, since it runs on the fly in the N-body run, our code can produce maps of the desired observables without storing large (or any) amounts of data for post-processing. We implemented our routines in the RAMSES N-body code and tested the implementationmore » using an example of weak lensing simulation. We analyse basic statistics of lensing convergence maps and find good agreement with semi-analytical methods. The ray tracing methodology presented here can be used in several cosmological analysis such as Sunyaev-Zel'dovich and integrated Sachs-Wolfe effect studies as well as modified gravity. Our code can also be used in cross-checks of the more conventional methods, which can be important in tests of theory systematics in preparation for upcoming large scale structure surveys.« less

The effect of autologous adipose derived mesenchymal stem cell therapy in the treatment of a large osteochondral defect of the knee following unsuccessful surgical intervention of osteochondritis dissecans - a case study.

PubMed

Freitag, Julien; Shah, Kiran; Wickham, James; Boyd, Richard; Tenen, Abi

2017-07-14

A prospective analysis of the effect of autologous adipose derived mesenchymal stem cell (MSC) therapy in the treatment of an osteochondral defect of the knee with early progressive osteoarthritis following unsuccessful surgical intervention of osteochondritis dissecans (OCD). After failed conventional management of OCD a patient undergoes intra-articular MSC therapy. Patient outcome measures included the Numeric Pain Rating Scale (NPRS), the Western Ontario and McMaster Universities Arthritis Index (WOMAC) and the Knee Injury and Osteoarthritis Outcome Score (KOOS). Structural outcome was assessed using MRI with the novel technique of T2 mapping used to indicate cartilage quality. Following MSC therapy the patient reported improvement in pain and function as measured by NPRS, WOMAC and KOOS. Repeat MRI analysis showed regeneration of cartilage. MRI T2 mapping indicated hyaline like cartilage regrowth. In this report, the use of MSCs, after unsuccessful conventional OCD management, resulted in structural, functional and pain improvement. These results highlight the need to further study the regenerative potential of MSC therapy. Australian and New Zealand Clinical Trial Registry Number - ACTRN12615000258550 (Date registered 19/03/2015 - retrospectively registered).

Methodology of remote sensing data interpretation and geological applications. [Brazil

NASA Technical Reports Server (NTRS)

Parada, N. D. J. (Principal Investigator); Veneziani, P.; Dosanjos, C. E.

1982-01-01

Elements of photointerpretation discussed include the analysis of photographic texture and structure as well as film tonality. The method used is based on conventional techniques developed for interpreting aerial black and white photographs. By defining the properties which characterize the form and individuality of dual images, homologous zones can be identified. Guy's logic method (1966) was adapted and used on functions of resolution, scale, and spectral characteristics of remotely sensed products. Applications of LANDSAT imagery are discussed for regional geological mapping, mineral exploration, hydrogeology, and geotechnical engineering in Brazil.

The ERTS-1 investigation (ER-600). Volume 3: ERTS-1 forest analysis

NASA Technical Reports Server (NTRS)

Erb, R. B.

1974-01-01

The Forest Analysis Team of the Lyndon B. Johnson Space Center Earth Observations Division conducted a year's investigation of LANDSAT 1 multispectral data to determine the size of forest features that could be detected and to determine the suitability for making forest classification maps. The Sam Houston National Forest of Texas was used as the test site. Using conventional interpretation and computer aided techniques, the team was able to differentiate up to 14 classes of forest features to an accuracy ranging between 55 and 84 percent.

Application of Particle Image Velocimetry and Reference Image Topography to jet shock cells using the hydraulic analogy

NASA Astrophysics Data System (ADS)

Kumar, Vaibhav; Ng, Ivan; Sheard, Gregory J.; Brocher, Eric; Hourigan, Kerry; Fouras, Andreas

2011-08-01

This paper examines the shock cell structure, vorticity and velocity field at the exit of an underexpanded jet nozzle using a hydraulic analogy and the Reference Image Topography technique. Understanding the flow in this region is important for the mitigation of screech, an aeroacoustic problem harmful to aircraft structures. Experiments are conducted on a water table, allowing detailed quantitative investigation of this important flow regime at a greatly reduced expense. Conventional Particle Image Velocimetry is employed to determine the velocity and vorticity fields of the nozzle exit region. Applying Reference Image Topography, the wavy water surface is reconstructed and when combined with the hydraulic analogy, provides a pressure map of the region. With this approach subtraction of surfaces is used to highlight the unsteady regions of the flow, which is not as convenient or quantitative with conventional Schlieren techniques. This allows a detailed analysis of the shock cell structures and their interaction with flow instabilities in the shear layer that are the underlying cause of jet screech.

Mapping Urban Risk: Flood Hazards, Race, & Environmental Justice In New York”

PubMed Central

Maantay, Juliana; Maroko, Andrew

2009-01-01

This paper demonstrates the importance of disaggregating population data aggregated by census tracts or other units, for more realistic population distribution/location. A newly-developed mapping method, the Cadastral-based Expert Dasymetric System (CEDS), calculates population in hyper-heterogeneous urban areas better than traditional mapping techniques. A case study estimating population potentially impacted by flood hazard in New York City compares the impacted population determined by CEDS with that derived by centroid-containment method and filtered areal weighting interpolation. Compared to CEDS, 37 percent and 72 percent fewer people are estimated to be at risk from floods city-wide, using conventional areal weighting of census data, and centroid-containment selection, respectively. Undercounting of impacted population could have serious implications for emergency management and disaster planning. Ethnic/racial populations are also spatially disaggregated to determine any environmental justice impacts with flood risk. Minorities are disproportionately undercounted using traditional methods. Underestimating more vulnerable sub-populations impairs preparedness and relief efforts. PMID:20047020

Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle.

PubMed

Hartman, Emily C; Jakobson, Christopher M; Favor, Andrew H; Lobba, Marco J; Álvarez-Benedicto, Ester; Francis, Matthew B; Tullman-Ercek, Danielle

2018-04-11

Self-assembling proteins are critical to biological systems and industrial technologies, but predicting how mutations affect self-assembly remains a significant challenge. Here, we report a technique, termed SyMAPS (Systematic Mutation and Assembled Particle Selection), that can be used to characterize the assembly competency of all single amino acid variants of a self-assembling viral structural protein. SyMAPS studies on the MS2 bacteriophage coat protein revealed a high-resolution fitness landscape that challenges some conventional assumptions of protein engineering. An additional round of selection identified a previously unknown variant (CP[T71H]) that is stable at neutral pH but less tolerant to acidic conditions than the wild-type coat protein. The capsids formed by this variant could be more amenable to disassembly in late endosomes or early lysosomes-a feature that is advantageous for delivery applications. In addition to providing a mutability blueprint for virus-like particles, SyMAPS can be readily applied to other self-assembling proteins.

The use of color infrared photography for wetlands mapping with special reference to shoreline and waterfowl habitat assessment

NASA Technical Reports Server (NTRS)

1973-01-01

Evaluation of low altitude oblique photography obtained by hand-held cameras was useful in determining specifications of operational mission requirements for conventional smaller-scaled vertical photography. Remote sensing techniques were used to assess the rapid destruction of marsh areas at Pointe Mouillee. In an estuarian environment where shoreline features change yearly, there is a need for revision in existing area maps. A land cover inventory, mapped from aerial photography, provided essential data necessary for determining adjacent lands suitable for marshland development. To quantitatively assess the wetlands environment, a detailed inventory of vegetative communities (19 categories) was made using color infrared photography and intensive ground truth. A carefully selected and well laid-out transect was found to be a key asset to photointerpretation and to the analysis of vegetative conditions. Transect data provided the interpreter with locally representative areas of various vegetative types. This facilitated development of a photointerpretation key. Additional information on vegetative conditions in the area was also obtained by evaluating the transect data.

Exploitation of the Intermittent SBAS (ISBAS) algorithm with COSMO-SkyMed data for landslide inventory mapping in north-western Sicily, Italy

NASA Astrophysics Data System (ADS)

Novellino, A.; Cigna, F.; Sowter, A.; Ramondini, M.; Calcaterra, D.

2017-03-01

A large scale study of landslide processes was undertaken by coupling conventional geomorphological field surveys with aerial photographs along with an advanced Interferometric Synthetic Aperture Radar (InSAR) analysis of ground instability in north-western Sicily. COSMO-SkyMed satellite images for the period between 2008 and 2011 were processed using the Intermittent Small BAseline Subset (ISBAS) technique, recently developed at the Department of Civil Engineering of the University of Nottingham. The use of ISBAS allowed the derivation of ground surface displacements across non-urbanized areas, thus overcoming one of the main limitations of conventional interferometric techniques. ISBAS provides ground motion information not only for urban but also for rural, woodland, grassland and agricultural terrains, which cover > 60% of north-western Sicily, thereby improving by 40 times in some cases, the slope instability investigation capabilities of InSAR methods. ISBAS ground motion data enabled the updating of the landslide inventory for the areas of Piana degli Albanesi and Marineo (over 130 km2), which encompass a number of active, dormant and inactive landslides according to the pre-existing landslide inventory maps produced through aerial photo-interpretation and local field checks. An average of ∼ 7000 ISBAS pixels km- 2 allowed the detection of small displacements in regions difficult to access. In particular, 226 landslides - mainly slides, flows and creep and four badlands were identified, comprising a total area of 25.3 km2. When compared to the previous landslide inventory maps, 84 phenomena were confirmed, 67 new events were detected and 79 previously mapped events were re-assessed, modifying their typology, boundary and/or state of activity. Because the InSAR method used here is designed to measure slow rates of velocity and therefore may not detect fast-moving, events such as falls and topples, the results for Piana degli Albanesi and Marineo demonstrate the validity of this method to support land management, underlying the time and cost benefits of a combined approach using traditional monitoring procedures and satellite InSAR methods especially if slow-moving slope movements prevail.

MRI technique for the snapshot imaging of quantitative velocity maps using RARE

NASA Astrophysics Data System (ADS)

Shiko, G.; Sederman, A. J.; Gladden, L. F.

2012-03-01

A quantitative PGSE-RARE pulse sequence was developed and successfully applied to the in situ dissolution of two pharmaceutical formulations dissolving over a range of timescales. The new technique was chosen over other existing fast velocity imaging techniques because it is T2 weighted, not T2∗ weighted, and is, therefore, robust for imaging time-varying interfaces and flow in magnetically heterogeneous systems. The complex signal was preserved intact by separating odd and even echoes to obtain two phase maps which are then averaged in post-processing. Initially, the validity of the technique was shown when imaging laminar flow in a pipe. Subsequently, the dissolution of two drugs was followed in situ, where the technique enables the imaging and quantification of changes in the form of the tablet and the flow field surrounding it at high spatial and temporal resolution. First, the complete 3D velocity field around an eroding salicylic acid tablet was acquired at a resolution of 98 × 49 μm2, within 20 min, and monitored over ˜13 h. The tablet was observed to experience a heterogeneous flow field and, hence a heterogeneous shear field, which resulted in the non-symmetric erosion of the tablet. Second, the dissolution of a fast dissolving immediate release tablet was followed using one-shot 2D velocity images acquired every 5.2 s at a resolution of 390 × 390 μm2. The quantitative nature of the technique and fast acquisition times provided invaluable information on the dissolution behaviour of this tablet, which had not been attainable previously with conventional quantitative MRI techniques.

An array processing system for lunar geochemical and geophysical data

NASA Technical Reports Server (NTRS)

Eliason, E. M.; Soderblom, L. A.

1977-01-01

A computerized array processing system has been developed to reduce, analyze, display, and correlate a large number of orbital and earth-based geochemical, geophysical, and geological measurements of the moon on a global scale. The system supports the activities of a consortium of about 30 lunar scientists involved in data synthesis studies. The system was modeled after standard digital image-processing techniques but differs in that processing is performed with floating point precision rather than integer precision. Because of flexibility in floating-point image processing, a series of techniques that are impossible or cumbersome in conventional integer processing were developed to perform optimum interpolation and smoothing of data. Recently color maps of about 25 lunar geophysical and geochemical variables have been generated.

Copy-move forgery detection utilizing Fourier-Mellin transform log-polar features

NASA Astrophysics Data System (ADS)

Dixit, Rahul; Naskar, Ruchira

2018-03-01

In this work, we address the problem of region duplication or copy-move forgery detection in digital images, along with detection of geometric transforms (rotation and rescale) and postprocessing-based attacks (noise, blur, and brightness adjustment). Detection of region duplication, following conventional techniques, becomes more challenging when an intelligent adversary brings about such additional transforms on the duplicated regions. In this work, we utilize Fourier-Mellin transform with log-polar mapping and a color-based segmentation technique using K-means clustering, which help us to achieve invariance to all the above forms of attacks in copy-move forgery detection of digital images. Our experimental results prove the efficiency of the proposed method and its superiority to the current state of the art.

New approach to estimating variability in visual field data using an image processing technique.

PubMed Central

Crabb, D P; Edgar, D F; Fitzke, F W; McNaught, A I; Wynn, H P

1995-01-01

AIMS--A new framework for evaluating pointwise sensitivity variation in computerised visual field data is demonstrated. METHODS--A measure of local spatial variability (LSV) is generated using an image processing technique. Fifty five eyes from a sample of normal and glaucomatous subjects, examined on the Humphrey field analyser (HFA), were used to illustrate the method. RESULTS--Significant correlation between LSV and conventional estimates--namely, HFA pattern standard deviation and short term fluctuation, were found. CONCLUSION--LSV is not dependent on normals' reference data or repeated threshold determinations, thus potentially reducing test time. Also, the illustrated pointwise maps of LSV could provide a method for identifying areas of fluctuation commonly found in early glaucomatous field loss. PMID:7703196

Large Area Crop Inventory Experiment (LACIE). Detecting and monitoring agricultural vegetative water stress over large areas using LANDSAT digital data. [Great Plains

NASA Technical Reports Server (NTRS)

Thompson, D. R.; Wehmanen, O. A. (Principal Investigator)

1978-01-01

The author has identified the following significant results. The Green Number Index technique which uses LANDSAT digital data from 5X6 nautical mile sampling frames was expanded to evaluate its usefulness in detecting and monitoring vegetative water stress over the Great Plains. At known growth stages for wheat, segments were classified as drought or non drought. Good agreement was found between the 18 day remotely sensed data and a weekly ground-based crop moisture index. Operational monitoring of the 1977 U.S.S.R. and Australian wheat crops indicated drought conditions. Drought isoline maps produced by the Green Number Index technique were in good agreement with conventional sources.

Sentinel node mapping for gastric cancer: a prospective multicenter trial in Japan.

PubMed

Kitagawa, Yuko; Takeuchi, Hiroya; Takagi, Yu; Natsugoe, Shoji; Terashima, Masanori; Murakami, Nozomu; Fujimura, Takashi; Tsujimoto, Hironori; Hayashi, Hideki; Yoshimizu, Nobunari; Takagane, Akinori; Mohri, Yasuhiko; Nabeshima, Kazuhito; Uenosono, Yoshikazu; Kinami, Shinichi; Sakamoto, Junichi; Morita, Satoshi; Aikou, Takashi; Miwa, Koichi; Kitajima, Masaki

2013-10-10

Complicated gastric lymphatic drainage potentially undermines the utility of sentinel node (SN) biopsy in patients with gastric cancer. Encouraged by several favorable single-institution reports, we conducted a multicenter, single-arm, phase II study of SN mapping that used a standardized dual tracer endoscopic injection technique. Patients with previously untreated cT1 or cT2 gastric adenocarcinomas < 4 cm in gross diameter were eligible for inclusion in this study. SN mapping was performed by using a standardized dual tracer endoscopic injection technique. Following biopsy of the identified SNs, mandatory comprehensive D2 or modified D2 gastrectomy was performed according to current Japanese Gastric Cancer Association guidelines. Among 433 patients who gave preoperative consent, 397 were deemed eligible on the basis of surgical findings. SN biopsy was performed in all patients, and the SN detection rate was 97.5% (387 of 397). Of 57 patients with lymph node metastasis by conventional hematoxylin and eosin staining, 93% (53 of 57) had positive SNs, and the accuracy of nodal evaluation for metastasis was 99% (383 of 387). Only four false-negative SN biopsies were observed, and pathologic analysis revealed that three of those biopsies were pT2 or tumors > 4 cm. We observed no serious adverse effects related to endoscopic tracer injection or the SN mapping procedure. The endoscopic dual tracer method for SN biopsy was confirmed as safe and effective when applied to the superficial, relatively small gastric adenocarcinomas included in this study.

Reservoir Modeling by Data Integration via Intermediate Spaces and Artificial Intelligence Tools in MPS Simulation Frameworks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahmadi, Rouhollah, E-mail: rouhollahahmadi@yahoo.com; Khamehchi, Ehsan

Conditioning stochastic simulations are very important in many geostatistical applications that call for the introduction of nonlinear and multiple-point data in reservoir modeling. Here, a new methodology is proposed for the incorporation of different data types into multiple-point statistics (MPS) simulation frameworks. Unlike the previous techniques that call for an approximate forward model (filter) for integration of secondary data into geologically constructed models, the proposed approach develops an intermediate space where all the primary and secondary data are easily mapped onto. Definition of the intermediate space, as may be achieved via application of artificial intelligence tools like neural networks andmore » fuzzy inference systems, eliminates the need for using filters as in previous techniques. The applicability of the proposed approach in conditioning MPS simulations to static and geologic data is verified by modeling a real example of discrete fracture networks using conventional well-log data. The training patterns are well reproduced in the realizations, while the model is also consistent with the map of secondary data.« less

Rapid detection methods for viable Mycobacterium avium subspecies paratuberculosis in milk and cheese.

PubMed

Botsaris, George; Slana, Iva; Liapi, Maria; Dodd, Christine; Economides, Constantinos; Rees, Catherine; Pavlik, Ivo

2010-07-31

Mycobacterium avium subsp. paratuberculosis (MAP) may have a role in the development of Crohn's disease in humans via the consumption of contaminated milk and milk products. Detection of MAP from milk and dairy products has been reported from countries on the European continent, Argentina, the UK and Australia. In this study three different methods (quantitative real time PCR, combined phage IS900 PCR and conventional cultivation) were used to detect the presence of MAP in bulk tank milk (BTM) and cheese originating from sheep, goat and mixed milks from farms and products in Cyprus. During the first survey the presence of MAP was detected in 63 (28.6%) of cows' BTM samples by quantitative real time PCR. A second survey of BTM used a new combined phage IS900 PCR assay, and in this case MAP was detected in 50 (22.2%) samples showing a good level of agreement by both methods. None of the herds tested were known to be affected by Johne's disease and the presence of viable MAP was confirmed by conventional culture in only two cases of cows BTM. This suggests that either rapid method used is more sensitive than the conventional culture when testing raw milk samples for MAP. The two isolates recovered from BTM were identified by IS1311 PCR REA as cattle and sheep strains, respectively. In contrast when cheese samples were tested, MAP DNA was detected by quantitative real time PCR in seven (25.0%) samples (n=28). However no viable MAP was detected when either the combined phage IS900 PCR or conventional culture methods were used. Copyright 2010 Elsevier B.V. All rights reserved.

Cubic map algebra functions for spatio-temporal analysis

USGS Publications Warehouse

Mennis, J.; Viger, R.; Tomlin, C.D.

2005-01-01

We propose an extension of map algebra to three dimensions for spatio-temporal data handling. This approach yields a new class of map algebra functions that we call "cube functions." Whereas conventional map algebra functions operate on data layers representing two-dimensional space, cube functions operate on data cubes representing two-dimensional space over a third-dimensional period of time. We describe the prototype implementation of a spatio-temporal data structure and selected cube function versions of conventional local, focal, and zonal map algebra functions. The utility of cube functions is demonstrated through a case study analyzing the spatio-temporal variability of remotely sensed, southeastern U.S. vegetation character over various land covers and during different El Nin??o/Southern Oscillation (ENSO) phases. Like conventional map algebra, the application of cube functions may demand significant data preprocessing when integrating diverse data sets, and are subject to limitations related to data storage and algorithm performance. Solutions to these issues include extending data compression and computing strategies for calculations on very large data volumes to spatio-temporal data handling.

3D reconstruction of a carotid bifurcation from 2D transversal ultrasound images.

PubMed

Yeom, Eunseop; Nam, Kweon-Ho; Jin, Changzhu; Paeng, Dong-Guk; Lee, Sang-Joon

2014-12-01

Visualizing and analyzing the morphological structure of carotid bifurcations are important for understanding the etiology of carotid atherosclerosis, which is a major cause of stroke and transient ischemic attack. For delineation of vasculatures in the carotid artery, ultrasound examinations have been widely employed because of a noninvasive procedure without ionizing radiation. However, conventional 2D ultrasound imaging has technical limitations in observing the complicated 3D shapes and asymmetric vasodilation of bifurcations. This study aims to propose image-processing techniques for better 3D reconstruction of a carotid bifurcation in a rat by using 2D cross-sectional ultrasound images. A high-resolution ultrasound imaging system with a probe centered at 40MHz was employed to obtain 2D transversal images. The lumen boundaries in each transverse ultrasound image were detected by using three different techniques; an ellipse-fitting, a correlation mapping to visualize the decorrelation of blood flow, and the ellipse-fitting on the correlation map. When the results are compared, the third technique provides relatively good boundary extraction. The incomplete boundaries of arterial lumen caused by acoustic artifacts are somewhat resolved by adopting the correlation mapping and the distortion in the boundary detection near the bifurcation apex was largely reduced by using the ellipse-fitting technique. The 3D lumen geometry of a carotid artery was obtained by volumetric rendering of several 2D slices. For the 3D vasodilatation of the carotid bifurcation, lumen geometries at the contraction and expansion states were simultaneously depicted at various view angles. The present 3D reconstruction methods would be useful for efficient extraction and construction of the 3D lumen geometries of carotid bifurcations from 2D ultrasound images. Copyright © 2014 Elsevier B.V. All rights reserved.

New spectral imaging techniques for blood oximetry in the retina

NASA Astrophysics Data System (ADS)

Alabboud, Ied; Muyo, Gonzalo; Gorman, Alistair; Mordant, David; McNaught, Andrew; Petres, Clement; Petillot, Yvan R.; Harvey, Andrew R.

2007-07-01

Hyperspectral imaging of the retina presents a unique opportunity for direct and quantitative mapping of retinal biochemistry - particularly of the vasculature where blood oximetry is enabled by the strong variation of absorption spectra with oxygenation. This is particularly pertinent both to research and to clinical investigation and diagnosis of retinal diseases such as diabetes, glaucoma and age-related macular degeneration. The optimal exploitation of hyperspectral imaging however, presents a set of challenging problems, including; the poorly characterised and controlled optical environment of structures within the retina to be imaged; the erratic motion of the eye ball; and the compounding effects of the optical sensitivity of the retina and the low numerical aperture of the eye. We have developed two spectral imaging techniques to address these issues. We describe first a system in which a liquid crystal tuneable filter is integrated into the illumination system of a conventional fundus camera to enable time-sequential, random access recording of narrow-band spectral images. Image processing techniques are described to eradicate the artefacts that may be introduced by time-sequential imaging. In addition we describe a unique snapshot spectral imaging technique dubbed IRIS that employs polarising interferometry and Wollaston prism beam splitters to simultaneously replicate and spectrally filter images of the retina into multiple spectral bands onto a single detector array. Results of early clinical trials acquired with these two techniques together with a physical model which enables oximetry map are reported.

On Voxel based Iso-Tumor Control Probabilty and Iso-Complication Maps for Selective Boosting and Selective Avoidance Intensity Modulated Radiotherapy

PubMed Central

Kim, Yusung; Tomé, Wolfgang A.

2010-01-01

Summary Voxel based iso-Tumor Control Probability (TCP) maps and iso-Complication maps are proposed as a plan-review tool especially for functional image-guided intensity-modulated radiotherapy (IMRT) strategies such as selective boosting (dose painting) and conformal avoidance IMRT. The maps employ voxel-based phenomenological biological dose-response models for target volumes and normal organs. Two IMRT strategies for prostate cancer, namely conventional uniform IMRT delivering an EUD = 84 Gy (equivalent uniform dose) to the entire PTV and selective boosting delivering an EUD = 82 Gy to the entire PTV, are investigated, to illustrate the advantages of this approach over iso-dose maps. Conventional uniform IMRT did yield a more uniform isodose map to the entire PTV while selective boosting did result in a nonuniform isodose map. However, when employing voxel based iso-TCP maps selective boosting exhibited a more uniform tumor control probability map compared to what could be achieved using conventional uniform IMRT, which showed TCP cold spots in high-risk tumor subvolumes despite delivering a higher EUD to the entire PTV. Voxel based iso-Complication maps are presented for rectum and bladder, and their utilization for selective avoidance IMRT strategies are discussed. We believe as the need for functional image guided treatment planning grows, voxel based iso-TCP and iso-Complication maps will become an important tool to assess the integrity of such treatment plans. PMID:21151734

Infrared and visible image fusion based on visual saliency map and weighted least square optimization

NASA Astrophysics Data System (ADS)

Ma, Jinlei; Zhou, Zhiqiang; Wang, Bo; Zong, Hua

2017-05-01

The goal of infrared (IR) and visible image fusion is to produce a more informative image for human observation or some other computer vision tasks. In this paper, we propose a novel multi-scale fusion method based on visual saliency map (VSM) and weighted least square (WLS) optimization, aiming to overcome some common deficiencies of conventional methods. Firstly, we introduce a multi-scale decomposition (MSD) using the rolling guidance filter (RGF) and Gaussian filter to decompose input images into base and detail layers. Compared with conventional MSDs, this MSD can achieve the unique property of preserving the information of specific scales and reducing halos near edges. Secondly, we argue that the base layers obtained by most MSDs would contain a certain amount of residual low-frequency information, which is important for controlling the contrast and overall visual appearance of the fused image, and the conventional "averaging" fusion scheme is unable to achieve desired effects. To address this problem, an improved VSM-based technique is proposed to fuse the base layers. Lastly, a novel WLS optimization scheme is proposed to fuse the detail layers. This optimization aims to transfer more visual details and less irrelevant IR details or noise into the fused image. As a result, the fused image details would appear more naturally and be suitable for human visual perception. Experimental results demonstrate that our method can achieve a superior performance compared with other fusion methods in both subjective and objective assessments.

High-resolution whole-brain DCE-MRI using constrained reconstruction: Prospective clinical evaluation in brain tumor patients

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guo, Yi, E-mail: yiguo@usc.edu; Zhu, Yinghua; Lingala, Sajan Goud

Purpose: To clinically evaluate a highly accelerated T1-weighted dynamic contrast-enhanced (DCE) MRI technique that provides high spatial resolution and whole-brain coverage via undersampling and constrained reconstruction with multiple sparsity constraints. Methods: Conventional (rate-2 SENSE) and experimental DCE-MRI (rate-30) scans were performed 20 minutes apart in 15 brain tumor patients. The conventional clinical DCE-MRI had voxel dimensions 0.9 × 1.3 × 7.0 mm{sup 3}, FOV 22 × 22 × 4.2 cm{sup 3}, and the experimental DCE-MRI had voxel dimensions 0.9 × 0.9 × 1.9 mm{sup 3}, and broader coverage 22 × 22 × 19 cm{sup 3}. Temporal resolution was 5 smore » for both protocols. Time-resolved images and blood–brain barrier permeability maps were qualitatively evaluated by two radiologists. Results: The experimental DCE-MRI scans showed no loss of qualitative information in any of the cases, while achieving substantially higher spatial resolution and whole-brain spatial coverage. Average qualitative scores (from 0 to 3) were 2.1 for the experimental scans and 1.1 for the conventional clinical scans. Conclusions: The proposed DCE-MRI approach provides clinically superior image quality with higher spatial resolution and coverage than currently available approaches. These advantages may allow comprehensive permeability mapping in the brain, which is especially valuable in the setting of large lesions or multiple lesions spread throughout the brain.« less

Applications of rapid prototyping technology in maxillofacial prosthetics.

PubMed

Sykes, Leanne M; Parrott, Andrew M; Owen, C Peter; Snaddon, Donald R

2004-01-01

The purpose of this study was to compare the accuracy, required time, and potential advantages of rapid prototyping technology with traditional methods in the manufacture of wax patterns for two facial prostheses. Two clinical situations were investigated: the production of an auricular prosthesis and the duplication of an existing maxillary prosthesis, using a conventional and a rapid prototyping method for each. Conventional wax patterns were created from impressions taken of a patient's remaining ear and an oral prosthesis. For the rapid prototyping method, a cast of the ear and the original maxillary prosthesis were scanned, and rapid prototyping was used to construct the wax patterns. For the auricular prosthesis, both patterns were refined clinically and then flasked and processed in silicone using routine procedures. Twenty-six independent observers evaluated these patterns by comparing them to the cast of the patient's remaining ear. For the duplication procedure, both wax patterns were scanned and compared to scans of the original prosthesis by generating color error maps to highlight volumetric changes. There was a significant difference in opinions for the two auricular prostheses with regard to shape and esthetic appeal, where the hand-carved prosthesis was found to be of poorer quality. The color error maps showed higher errors with the conventional duplication process compared with the rapid prototyping method. The main advantage of rapid prototyping is the ability to produce physical models using digital methods instead of traditional impression techniques. The disadvantage of equipment costs could be overcome by establishing a centralized service.

Integrating Databases with Maps: The Delivery of Cultural Data through TimeMap.

ERIC Educational Resources Information Center

Johnson, Ian

TimeMap is a unique integration of database management, metadata and interactive maps, designed to contextualise and deliver cultural data through maps. TimeMap extends conventional maps with the time dimension, creating and animating maps "on-the-fly"; delivers them as a kiosk application or embedded in Web pages; links flexibly to…

Hybrid dynamic radioactive particle tracking (RPT) calibration technique for multiphase flow systems

NASA Astrophysics Data System (ADS)

Khane, Vaibhav; Al-Dahhan, Muthanna H.

2017-04-01

The radioactive particle tracking (RPT) technique has been utilized to measure three-dimensional hydrodynamic parameters for multiphase flow systems. An analytical solution to the inverse problem of the RPT technique, i.e. finding the instantaneous tracer positions based upon instantaneous counts received in the detectors, is not possible. Therefore, a calibration to obtain a counts-distance map is needed. There are major shortcomings in the conventional RPT calibration method due to which it has limited applicability in practical applications. In this work, the design and development of a novel dynamic RPT calibration technique are carried out to overcome the shortcomings of the conventional RPT calibration method. The dynamic RPT calibration technique has been implemented around a test reactor with 1foot in diameter and 1 foot in height using Cobalt-60 as an isotopes tracer particle. Two sets of experiments have been carried out to test the capability of novel dynamic RPT calibration. In the first set of experiments, a manual calibration apparatus has been used to hold a tracer particle at known static locations. In the second set of experiments, the tracer particle was moved vertically downwards along a straight line path in a controlled manner. The obtained reconstruction results about the tracer particle position were compared with the actual known position and the reconstruction errors were estimated. The obtained results revealed that the dynamic RPT calibration technique is capable of identifying tracer particle positions with a reconstruction error between 1 to 5.9 mm for the conditions studied which could be improved depending on various factors outlined here.

Geometry Processing of Conventionally Produced Mouse Brain Slice Images.

PubMed

Agarwal, Nitin; Xu, Xiangmin; Gopi, M

2018-04-21

Brain mapping research in most neuroanatomical laboratories relies on conventional processing techniques, which often introduce histological artifacts such as tissue tears and tissue loss. In this paper we present techniques and algorithms for automatic registration and 3D reconstruction of conventionally produced mouse brain slices in a standardized atlas space. This is achieved first by constructing a virtual 3D mouse brain model from annotated slices of Allen Reference Atlas (ARA). Virtual re-slicing of the reconstructed model generates ARA-based slice images corresponding to the microscopic images of histological brain sections. These image pairs are aligned using a geometric approach through contour images. Histological artifacts in the microscopic images are detected and removed using Constrained Delaunay Triangulation before performing global alignment. Finally, non-linear registration is performed by solving Laplace's equation with Dirichlet boundary conditions. Our methods provide significant improvements over previously reported registration techniques for the tested slices in 3D space, especially on slices with significant histological artifacts. Further, as one of the application we count the number of neurons in various anatomical regions using a dataset of 51 microscopic slices from a single mouse brain. To the best of our knowledge the presented work is the first that automatically registers both clean as well as highly damaged high-resolutions histological slices of mouse brain to a 3D annotated reference atlas space. This work represents a significant contribution to this subfield of neuroscience as it provides tools to neuroanatomist for analyzing and processing histological data. Copyright © 2018 Elsevier B.V. All rights reserved.

High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells*

PubMed Central

Kanderova, Veronika; Kuzilkova, Daniela; Stuchly, Jan; Vaskova, Martina; Brdicka, Tomas; Fiser, Karel; Hrusak, Ondrej; Lund-Johansen, Fridtjof

2016-01-01

Acute leukemia is a disease pathologically manifested at both genomic and proteomic levels. Molecular genetic technologies are currently widely used in clinical research. In contrast, sensitive and high-throughput proteomic techniques for performing protein analyses in patient samples are still lacking. Here, we used a technology based on size exclusion chromatography followed by immunoprecipitation of target proteins with an antibody bead array (Size Exclusion Chromatography-Microsphere-based Affinity Proteomics, SEC-MAP) to detect hundreds of proteins from a single sample. In addition, we developed semi-automatic bioinformatics tools to adapt this technology for high-content proteomic screening of pediatric acute leukemia patients. To confirm the utility of SEC-MAP in leukemia immunophenotyping, we tested 31 leukemia diagnostic markers in parallel by SEC-MAP and flow cytometry. We identified 28 antibodies suitable for both techniques. Eighteen of them provided excellent quantitative correlation between SEC-MAP and flow cytometry (p < 0.05). Next, SEC-MAP was applied to examine 57 diagnostic samples from patients with acute leukemia. In this assay, we used 632 different antibodies and detected 501 targets. Of those, 47 targets were differentially expressed between at least two of the three acute leukemia subgroups. The CD markers correlated with immunophenotypic categories as expected. From non-CD markers, we found DBN1, PAX5, or PTK2 overexpressed in B-cell precursor acute lymphoblastic leukemias, LAT, SH2D1A, or STAT5A overexpressed in T-cell acute lymphoblastic leukemias, and HCK, GLUD1, or SYK overexpressed in acute myeloid leukemias. In addition, OPAL1 overexpression corresponded to ETV6-RUNX1 chromosomal translocation. In summary, we demonstrated that SEC-MAP technology is a powerful tool for detecting hundreds of proteins in clinical samples obtained from pediatric acute leukemia patients. It provides information about protein size and reveals differences in protein expression between particular leukemia subgroups. Forty-seven of SEC-MAP identified targets were validated by other conventional method in this study. PMID:26785729

Sub-micron Raman Mapping of Ultramafic Fault Rock Textures

NASA Astrophysics Data System (ADS)

Tarling, M. S.; Rooney, J. S.; Smith, S. A. F.; Gordon, K. C.

2016-12-01

Deciphering the often complex temporal and microstructural relationships between the serpentine group minerals - antigorite, chrysotile, lizardite and polygonal serpentine - is essential for a proper understanding of the serpentinization process in a range of geodynamic settings. Conventional techniques such as optical microscopy, quantitative XRD and SEM-EDS often fail to correctly identify the four varieties of serpentine. Transmission electron microscopy can be used to successfully identify these minerals, but complex sample preparation and very small sample sizes (1-10's microns) means that microstructural context is difficult to maintain. Building on previous work (Petriglieri et al. 2015, J. Raman Spectrosc.) that introduced a methodology for Raman mapping on thin sections, we present the initial results of large-area and high-resolution (at the optical limit) Raman mapping that allows us to unambiguously distinguish and contextualise the serpentine minerals within their microstructural context. Measurements were performed on flat, SYTON-polished petrographic thin sections using a Witec Raman microscope equipped with a piezoelectric nano-positioning x-y stage. With a laser wavelength of 532 nm and a 100x dry objective, spatial resolution approaching 360 nm, as predicted by the Abbe equation, can readily be achieved. Minerals are primarily discerned by examining the Raman peaks in the high wavenumber spectral range of 3600-3710 cm-1, corresponding to OH-stretching vibrations. To illustrate the technique, Raman maps were acquired on several samples from the Livingstone Fault, a major terrane boundary in New Zealand that is localized in a mélange of ultramafic rocks including harzburgite and serpentinite. The maps highlight fine-scale intergrowths of antigorite, lizardite, chrysotile and related minerals (e.g. brucite, magnetite) at a sub-micron level over large areas (10's of microns to mm scale), features that are inaccessible or not visible using other techniques. In addition, the high-resolution mapping of discrete magnetite-bearing serpentinite slip surfaces has revealed the presence of 10-50 μm patches of nano-crystalline forsterite and enstatite, which may be the result of localized, faulting-induced, serpentinite dehydration.

Detection of soft-tissue sarcoma recurrence: added value of functional MR imaging techniques at 3.0 T.

PubMed

Del Grande, Filippo; Subhawong, Ty; Weber, Kristy; Aro, Michael; Mugera, Charles; Fayad, Laura M

2014-05-01

To determine the added value of functional magnetic resonance (MR) sequences (dynamic contrast material-enhanced [DCE] and quantitative diffusion-weighted [DW] imaging with apparent diffusion coefficient [ADC] mapping) for the detection of recurrent soft-tissue sarcomas following surgical resection. This retrospective study was approved by the institutional review board. The requirement to obtain informed consent was waived. Thirty-seven patients referred for postoperative surveillance after resection of soft-tissue sarcoma (35 with high-grade sarcoma) were studied. Imaging at 3.0 T included conventional (T1-weighted, fluid-sensitive, and contrast-enhanced T1-weighted imaging) and functional (DCE MR imaging, DW imaging with ADC mapping) sequences. Recurrences were confirmed with biopsy or resection. A disease-free state was determined with at least 6 months of follow-up. Two readers independently recorded the signal and morphologic characteristics with conventional sequences, the presence or absence of arterial enhancement at DCE MR imaging, and ADCs of the surgical bed. The accuracy of conventional MR imaging in the detection of recurrence was compared with that with the addition of functional sequences. The Fisher exact and Wilcoxon rank sum tests were used to define the accuracy of imaging features, the Cohen κ and Lin interclass correlation were used to define interobserver variability, and receiver operating characteristic analysis was used to define a threshold to detect recurrence and assess reader confidence after the addition of functional imaging to conventional sequences. There were six histologically proved recurrences in 37 patients. Sensitivity and specificity of MR imaging in the detection of tumor recurrence were 100% (six of six patients) and 52% (16 of 31 patients), respectively, with conventional sequences, 100% (six of six patients) and 97% (30 of 31 patients) with the addition of DCE MR imaging, and 60% (three of five patients) and 97% (30 of 31 patients) with the addition of DW imaging and ADC mapping. The average ADC of recurrence (1.08 mm(2)/sec ± 0.19) was significantly different from those of postoperative scarring (0.9 mm(2)/sec ± 0.00) and hematomas (2.34 mm(2)/sec ± 0.72) (P = .03 for both). The addition of functional MR sequences to a routine MR protocol, in particular DCE MR imaging, offers a specificity of more than 95% for distinguishing recurrent sarcoma from postsurgical scarring.

A comparison between probability and information measures of uncertainty in a simulated soil map and the economic value of imperfect soil information.

NASA Astrophysics Data System (ADS)

Lark, R. Murray

2014-05-01

Conventionally the uncertainty of a conventional soil map has been expressed in terms of the mean purity of its map units: the probability that the soil profile class examined at a site would be found to correspond to the eponymous class of the simple map unit that is delineated there (Burrough et al, 1971). This measure of uncertainty has an intuitive meaning and is used for quality control in soil survey contracts (Western, 1978). However, it may be of limited value to the manager or policy maker who wants to decide whether the map provides a basis for decision making, and whether the cost of producing a better map would be justified. In this study I extend a published analysis of the economic implications of uncertainty in a soil map (Giasson et al., 2000). A decision analysis was developed to assess the economic value of imperfect soil map information for agricultural land use planning. Random error matrices for the soil map units were then generated, subject to constraints which ensure consistency with fixed frequencies of the different soil classes. For each error matrix the mean map unit purity was computed, and the value of the implied imperfect soil information was computed by the decision analysis. An alternative measure of the uncertainty in a soil map was considered. This is the mean soil map information which is the difference between the information content of a soil observation, at a random location in the region, and the information content of a soil observation given that the map unit is known. I examined the relationship between the value of imperfect soil information and the purity and information measures of map uncertainty. In both cases there was considerable variation in the economic value of possible maps with fixed values of the uncertainty measure. However, the correlation was somewhat stronger with the information measure, and there was a clear upper bound on the value of an imperfect soil map when the mean information takes some particular value. This suggests that the information measure may be a useful one for general communication of the value of soil and similar thematic data. Burrough, P.A., Beckett, P.H.T., Jarvis, M.G., 1971. The relation between cost and utility in soil survey. J. Soil Sci. 22, 359-394. Giasson, E., van Es, C, van Wambeke, A., Bryant, R.B. 2000. Assessing the economic value of soil information using decision analysis techniques. Soil Science 165, 971-978 Western, S., 1978. Soil survey contracts and quality control. Oxford Univ. Press, Oxford.

From Conventional Radiotracer Tc-99(m) with Blue Dye to Indocyanine Green Fluorescence: A Comparison of Methods Towards Optimization of Sentinel Lymph Node Mapping in Early Stage Cervical Cancer for a Laparoscopic Approach.

PubMed

Buda, Alessandro; Papadia, Andrea; Zapardiel, Ignacio; Vizza, Enrico; Ghezzi, Fabio; De Ponti, Elena; Lissoni, Andrea Alberto; Imboden, Sara; Diestro, Maria Dolores; Verri, Debora; Gasparri, Maria Luisa; Bussi, Beatrice; Di Martino, Giampaolo; de la Noval, Begoña Diaz; Mueller, Michael; Crivellaro, Cinzia

2016-09-01

The credibility of sentinel lymph node (SLN) mapping is becoming increasingly more established in cervical cancer. We aimed to assess the sensitivity of SLN biopsy in terms of detection rate and bilateral mapping in women with cervical cancer by comparing technetium-99 radiocolloid (Tc-99(m)) and blue dye (BD) versus fluorescence mapping with indocyanine green (ICG). Data of patients with cervical cancer stage 1A2 to 1B1 from 5 European institutions were retrospectively reviewed. All centers used a laparoscopic approach with the same intracervical dye injection. Detection rate and bilateral mapping of ICG were compared, respectively, with results obtained by standard Tc-99(m) with BD. Overall, 76 (53 %) of 144 of women underwent preoperative SLN mapping with radiotracer and intraoperative BD, whereas 68 of (47 %) 144 patients underwent mapping using intraoperative ICG. The detection rate of SLN mapping was 96 % and 100 % for Tc-99(m) with BD and ICG, respectively. Bilateral mapping was achieved in 98.5 % for ICG and 76.3 % for Tc-99(m) with BD; this difference was statistically significant (p < 0.0001). The fluorescence SLN mapping with ICG achieved a significantly higher detection rate and bilateral mapping compared to standard radiocolloid and BD technique in women with early stage cervical cancer. Nodal staging with an intracervical injection of ICG is accurate, safe, and reproducible in patients with cervical cancer. Before replacing lymphadenectomy completely, the additional value of fluorescence SLN mapping on both perioperative morbidity and survival should be explored and confirmed by ongoing controlled trials.

High-dynamic range imaging techniques based on both color-separation algorithms used in conventional graphic arts and the human visual perception modeling

NASA Astrophysics Data System (ADS)

Lo, Mei-Chun; Hsieh, Tsung-Hsien; Perng, Ruey-Kuen; Chen, Jiong-Qiao

2010-01-01

The aim of this research is to derive illuminant-independent type of HDR imaging modules which can optimally multispectrally reconstruct of every color concerned in high-dynamic-range of original images for preferable cross-media color reproduction applications. Each module, based on either of broadband and multispectral approach, would be incorporated models of perceptual HDR tone-mapping, device characterization. In this study, an xvYCC format of HDR digital camera was used to capture HDR scene images for test. A tone-mapping module was derived based on a multiscale representation of the human visual system and used equations similar to a photoreceptor adaptation equation, proposed by Michaelis-Menten. Additionally, an adaptive bilateral type of gamut mapping algorithm, using approach of a multiple conversing-points (previously derived), was incorporated with or without adaptive Un-sharp Masking (USM) to carry out the optimization of HDR image rendering. An LCD with standard color space of Adobe RGB (D65) was used as a soft-proofing platform to display/represent HDR original RGB images, and also evaluate both renditionquality and prediction-performance of modules derived. Also, another LCD with standard color space of sRGB was used to test gamut-mapping algorithms, used to be integrated with tone-mapping module derived.

Participatory and Collaborative Digital Mapping to Enhance Disaster Resilience

NASA Astrophysics Data System (ADS)

Liu, Wei; Dugar, Sumit; McCallum, Ian; Brown, Sarah; See, Linda; Mechler, Reinhard

2017-04-01

Critical knowledge gaps seriously hinder disaster risk reduction and resilience building efforts, especially in disaster prone least developing countries. The information scarcity is highest at local levels, in terms of the spatial information of risk, resources and capacities of communities. We propose a general procedure that combines community-based participatory mapping processes, which has been widely used by in various government and non-government organization projects in the fields of natural resources management, disaster risk reduction and rural development, and the emerging collaborative digital mapping techniques to tackle this challenge. We demonstrate the value and potential of this general participatory and collaborative digital mapping by conducting a pilot study in the flood prone lower Karnali River basin in Western Nepal. We engaged a range of stakeholders to generate geographic information on resources, capacities and flood risks of pilot communities according to local needs. The new digital community maps are richer in contents, more accurate, and easier to update and share than those produced using conventional Vulnerability and Capacity Assessments (VCAs), a variant of Participatory Rural Appraisal (PRA) that is widely used by in various government and non-government organizations. This approach, as an inclusive form of risk knowledge co-generation, can play a critical role in improving evidence-based understanding of disaster risk and enhance disaster resilience worldwide.

Dynamic Projection Mapping onto Deforming Non-Rigid Surface Using Deformable Dot Cluster Marker.

PubMed

Narita, Gaku; Watanabe, Yoshihiro; Ishikawa, Masatoshi

2017-03-01

Dynamic projection mapping for moving objects has attracted much attention in recent years. However, conventional approaches have faced some issues, such as the target objects being limited to rigid objects, and the limited moving speed of the targets. In this paper, we focus on dynamic projection mapping onto rapidly deforming non-rigid surfaces with a speed sufficiently high that a human does not perceive any misalignment between the target object and the projected images. In order to achieve such projection mapping, we need a high-speed technique for tracking non-rigid surfaces, which is still a challenging problem in the field of computer vision. We propose the Deformable Dot Cluster Marker (DDCM), a novel fiducial marker for high-speed tracking of non-rigid surfaces using a high-frame-rate camera. The DDCM has three performance advantages. First, it can be detected even when it is strongly deformed. Second, it realizes robust tracking even in the presence of external and self occlusions. Third, it allows millisecond-order computational speed. Using DDCM and a high-speed projector, we realized dynamic projection mapping onto a deformed sheet of paper and a T-shirt with a speed sufficiently high that the projected images appeared to be printed on the objects.

QTL mapping for downy mildew resistance in cucumber via bulked segregant analysis using next-generation sequencing and conventional methods.

PubMed

Win, Khin Thanda; Vegas, Juan; Zhang, Chunying; Song, Kihwan; Lee, Sanghyeob

2017-01-01

QTL mapping using NGS-assisted BSA was successfully applied to an F 2 population for downy mildew resistance in cucumber. QTLs detected by NGS-assisted BSA were confirmed by conventional QTL analysis. Downy mildew (DM), caused by Pseudoperonospora cubensis, is one of the most destructive foliar diseases in cucumber. QTL mapping is a fundamental approach for understanding the genetic inheritance of DM resistance in cucumber. Recently, many studies have reported that a combination of bulked segregant analysis (BSA) and next-generation sequencing (NGS) can be a rapid and cost-effective way of mapping QTLs. In this study, we applied NGS-assisted BSA to QTL mapping of DM resistance in cucumber and confirmed the results by conventional QTL analysis. By sequencing two DNA pools each consisting of ten individuals showing high resistance and susceptibility to DM from a F 2 population, we identified single nucleotide polymorphisms (SNPs) between the two pools. We employed a statistical method for QTL mapping based on these SNPs. Five QTLs, dm2.2, dm4.1, dm5.1, dm5.2, and dm6.1, were detected and dm2.2 showed the largest effect on DM resistance. Conventional QTL analysis using the F 2 confirmed dm2.2 (R 2  = 10.8-24 %) and dm5.2 (R 2  = 14-27.2 %) as major QTLs and dm4.1 (R 2  = 8 %) as two minor QTLs, but could not detect dm5.1 and dm6.1. A new QTL on chromosome 2, dm2.1 (R 2  = 28.2 %) was detected by the conventional QTL method using an F 3 population. This study demonstrated the effectiveness of NGS-assisted BSA for mapping QTLs conferring DM resistance in cucumber and revealed the unique genetic inheritance of DM resistance in this population through two distinct major QTLs on chromosome 2 that mainly harbor DM resistance.

Computer mapping of LANDSAT data for environmental applications

NASA Technical Reports Server (NTRS)

Rogers, R. H. (Principal Investigator); Mckeon, J. B.; Reed, L. E.; Schmidt, N. F.; Schecter, R. N.

1975-01-01

The author has identified the following significant results. Land cover overlays and maps produced from LANDSAT are providing information on existing land use and resources throughout the 208 study area. The overlays are being used to delineate drainage areas of a predominant land cover type. Information on cover type is also being combined with other pertinent data to develop estimates of sediment and nutrients flows from the drainage area. The LANDSAT inventory of present land cover together with population projects is providing a basis for developing maps of anticipated land use patterns required to evaluate impact on water quality which may result from these patterns. Overlays of forest types were useful for defining wildlife habitat and vegetational resources in the region. LANDSAT data and computer assisted interpretation was found to be a rapid cost effective procedure for inventorying land cover on a regional basis. The entire 208 inventory which include acquisition of ground truth, LANDSAT tapes, computer processing, and production of overlays and coded tapes was completed within a period of 2 months at a cost of about 0.6 cents per acre, a significant improvement in time and cost over conventional photointerpretation and mapping techniques.

High-throughput characterization of film thickness in thin film materials libraries by digital holographic microscopy.

PubMed

Lai, Yiu Wai; Krause, Michael; Savan, Alan; Thienhaus, Sigurd; Koukourakis, Nektarios; Hofmann, Martin R; Ludwig, Alfred

2011-10-01

A high-throughput characterization technique based on digital holography for mapping film thickness in thin-film materials libraries was developed. Digital holographic microscopy is used for fully automatic measurements of the thickness of patterned films with nanometer resolution. The method has several significant advantages over conventional stylus profilometry: it is contactless and fast, substrate bending is compensated, and the experimental setup is simple. Patterned films prepared by different combinatorial thin-film approaches were characterized to investigate and demonstrate this method. The results show that this technique is valuable for the quick, reliable and high-throughput determination of the film thickness distribution in combinatorial materials research. Importantly, it can also be applied to thin films that have been structured by shadow masking.

Prediction of iron oxide contents using diffuse reflectance spectroscopy

NASA Astrophysics Data System (ADS)

Marques, José, Jr.; Arantes Camargo, Livia

2015-04-01

Determining soil iron oxides using conventional analysis is relatively unfeasible when large areas are mapped, with the aim of characterizing spatial variability. Diffuse reflectance spectroscopy (DRS) is rapid, less expensive, non-destructive and sometimes more accurate than conventional analysis. Furthermore, this technique allows the simultaneous characterization of many soil attributes with agronomic and environmental relevance. This study aims to assess the DRS capability to predict iron oxides content -hematite and goethite - , characterizing their spatial variability in soils of Brazil. Soil samples collected from an 800-hectare area were scanned in the visible and near-infrared spectral range. Moreover, chemometric calibration was obtained through partial least-squares regression (PLSR). Then, spatial distribution maps of the attributes were constructed using predicted values from calibrated models through geostatistical methods. The studied area presented soils with varied contents of iron oxides as examples for the Oxisols and Entisols. In the spectra of each soil is observed that the reflectance decreases with the content of iron oxides present in the soil. In soils with a high content of iron oxides can be observed more pronounced concavities between 380 and 1100 nm which are characteristic of the presence of these oxides. In soils with higher reflectance it were observed concavity characteristics due to the presence of kaolinite, in agreement with the low iron contents of those soils. The best accuracy of prediction models [residual prediction deviation (RPD) = 1.7] was obtained for goethite within the visible region (380-800 nm), and for hematite (RPD = 2.0) within the visible near infrared (380-2300 nm). The maps of goethite and hematite predicted showed the spatial distribution pattern similar to the maps of clay and iron extracted by dithionite-citrate-bicarbonate, being consistent with the iron oxide contents of soils present in the study area. These results confirm the value of DRS in the mapping of iron oxides in large areas at detailed scale.

Design and validation of a tissue bath 3-D printed with PLA for optically mapping suspended whole heart preparations.

PubMed

Entz, Michael; King, D Ryan; Poelzing, Steven

2017-12-01

With the sudden increase in affordable manufacturing technologies, the relationship between experimentalists and the designing process for laboratory equipment is rapidly changing. While experimentalists are still dependent on engineers and manufacturers for precision electrical, mechanical, and optical equipment, it has become a realistic option for in house manufacturing of other laboratory equipment with less precise design requirements. This is possible due to decreasing costs and increasing functionality of desktop three-dimensional (3-D) printers and 3-D design software. With traditional manufacturing methods, iterative design processes are expensive and time consuming, and making more than one copy of a custom piece of equipment is prohibitive. Here, we provide an overview to design a tissue bath and stabilizer for a customizable, suspended, whole heart optical mapping apparatus that can be produced significantly faster and less expensive than conventional manufacturing techniques. This was accomplished through a series of design steps to prevent fluid leakage in the areas where the optical imaging glass was attached to the 3-D printed bath. A combination of an acetone dip along with adhesive was found to create a water tight bath. Optical mapping was used to quantify cardiac conduction velocity and action potential duration to compare 3-D printed baths to a bath that was designed and manufactured in a machine shop. Importantly, the manufacturing method did not significantly affect conduction, action potential duration, or contraction, suggesting that 3-D printed baths are equally effective for optical mapping experiments. NEW & NOTEWORTHY This article details three-dimensional printable equipment for use in suspended whole heart optical mapping experiments. This equipment is less expensive than conventional manufactured equipment as well as easily customizable to the experimentalist. The baths can be waterproofed using only a three-dimensional printer, acetone, a glass microscope slide, c-clamps, and adhesive. Copyright © 2017 the American Physiological Society.

Microanalysis of dental caries using laser-scanned fluorescence

NASA Astrophysics Data System (ADS)

Barron, Joseph R.; Paton, Barry E.; Zakariasen, Kenneth L.

1992-06-01

It is well known that enamel and dentin fluoresce when illuminated by short-wavelength optical radiation. Fluorescence emission from carious and non-carious regions of teeth have been studied using a new experimental scanning technique for fluorescence analysis of dental sections. Scanning in 2 dimensions will allow surface maps of dental caries to be created. These surface images are then enhanced using the conventional and newer image processing techniques. Carious regions can be readily identified and contour maps can be used to graphically display the degree of damage on both surfaces and transverse sections. Numerous studies have shown that carious fluorescence is significantly different than non-carious regions. The scanning laser fluorescence spectrometer focuses light from a 25 mW He-Cd laser at 442 nm through an objective lens onto a cross-section area as small as 3 micrometers in diameter. Microtome prepared dental samples 100 micrometers thick are laid flat onto an optical bench perpendicular to the incident beam. The sample is moved under computer control in X & Y with an absolute precision of 0.1 micrometers . The backscattered light is both spatial and wavelength filtered before being measured on a long wavelength sensitized photomultiplier tube. High precision analysis of dental samples allow detailed maps of carious regions to be determined. Successive images allow time studies of caries growth and even the potential for remineralization studies of decalcified regions.

Genome-wide mapping of DNase I hypersensitive sites in rare cell populations using single-cell DNase sequencing.

PubMed

Cooper, James; Ding, Yi; Song, Jiuzhou; Zhao, Keji

2017-11-01

Increased chromatin accessibility is a feature of cell-type-specific cis-regulatory elements; therefore, mapping of DNase I hypersensitive sites (DHSs) enables the detection of active regulatory elements of transcription, including promoters, enhancers, insulators and locus-control regions. Single-cell DNase sequencing (scDNase-seq) is a method of detecting genome-wide DHSs when starting with either single cells or <1,000 cells from primary cell sources. This technique enables genome-wide mapping of hypersensitive sites in a wide range of cell populations that cannot be analyzed using conventional DNase I sequencing because of the requirement for millions of starting cells. Fresh cells, formaldehyde-cross-linked cells or cells recovered from formalin-fixed paraffin-embedded (FFPE) tissue slides are suitable for scDNase-seq assays. To generate scDNase-seq libraries, cells are lysed and then digested with DNase I. Circular carrier plasmid DNA is included during subsequent DNA purification and library preparation steps to prevent loss of the small quantity of DHS DNA. Libraries are generated for high-throughput sequencing on the Illumina platform using standard methods. Preparation of scDNase-seq libraries requires only 2 d. The materials and molecular biology techniques described in this protocol should be accessible to any general molecular biology laboratory. Processing of high-throughput sequencing data requires basic bioinformatics skills and uses publicly available bioinformatics software.

MRI technique for the snapshot imaging of quantitative velocity maps using RARE.

PubMed

Shiko, G; Sederman, A J; Gladden, L F

2012-03-01

A quantitative PGSE-RARE pulse sequence was developed and successfully applied to the in situ dissolution of two pharmaceutical formulations dissolving over a range of timescales. The new technique was chosen over other existing fast velocity imaging techniques because it is T(2) weighted, not T(2)(∗) weighted, and is, therefore, robust for imaging time-varying interfaces and flow in magnetically heterogeneous systems. The complex signal was preserved intact by separating odd and even echoes to obtain two phase maps which are then averaged in post-processing. Initially, the validity of the technique was shown when imaging laminar flow in a pipe. Subsequently, the dissolution of two drugs was followed in situ, where the technique enables the imaging and quantification of changes in the form of the tablet and the flow field surrounding it at high spatial and temporal resolution. First, the complete 3D velocity field around an eroding salicylic acid tablet was acquired at a resolution of 98×49 μm(2), within 20 min, and monitored over ∼13 h. The tablet was observed to experience a heterogeneous flow field and, hence a heterogeneous shear field, which resulted in the non-symmetric erosion of the tablet. Second, the dissolution of a fast dissolving immediate release tablet was followed using one-shot 2D velocity images acquired every 5.2 s at a resolution of 390×390 μm(2). The quantitative nature of the technique and fast acquisition times provided invaluable information on the dissolution behaviour of this tablet, which had not been attainable previously with conventional quantitative MRI techniques. Copyright © 2012 Elsevier Inc. All rights reserved.

Evaluation of seismic design spectrum based on UHS implementing fourth-generation seismic hazard maps of Canada

NASA Astrophysics Data System (ADS)

Ahmed, Ali; Hasan, Rafiq; Pekau, Oscar A.

2016-12-01

Two recent developments have come into the forefront with reference to updating the seismic design provisions for codes: (1) publication of new seismic hazard maps for Canada by the Geological Survey of Canada, and (2) emergence of the concept of new spectral format outdating the conventional standardized spectral format. The fourth -generation seismic hazard maps are based on enriched seismic data, enhanced knowledge of regional seismicity and improved seismic hazard modeling techniques. Therefore, the new maps are more accurate and need to incorporate into the Canadian Highway Bridge Design Code (CHBDC) for its next edition similar to its building counterpart National Building Code of Canada (NBCC). In fact, the code writers expressed similar intentions with comments in the commentary of CHBCD 2006. During the process of updating codes, NBCC, and AASHTO Guide Specifications for LRFD Seismic Bridge Design, American Association of State Highway and Transportation Officials, Washington (2009) lowered the probability level from 10 to 2% and 10 to 5%, respectively. This study has brought five sets of hazard maps corresponding to 2%, 5% and 10% probability of exceedance in 50 years developed by the GSC under investigation. To have a sound statistical inference, 389 Canadian cities are selected. This study shows the implications of the changes of new hazard maps on the design process (i.e., extent of magnification or reduction of the design forces).

Application of acoustic imaging techniques on snowmobile pass-by noise.

PubMed

Padois, Thomas; Berry, Alain

2017-02-01

Snowmobile manufacturers invest important efforts to reduce the noise emission of their products. The noise sources of snowmobiles are multiple and closely spaced, leading to difficult source separation in practice. In this study, source imaging results for snowmobile pass-by noise are discussed. The experiments involve a 193-microphone Underbrink array, with synchronization of acoustic with video data provided by a high-speed camera. Both conventional beamforming and Clean-SC deconvolution are implemented to provide noise source maps of the snowmobile. The results clearly reveal noise emission from the engine, exhaust, and track depending on the frequency range considered.

Co-axial Electrospun Polyacrylonitrile-Poly(methylmethacrylate) Nanofibers: Atomic Force Microscopy and Compositional Characterization

PubMed Central

Zander, N.E.; Strawhecker, K.E.; Orlicki, J.A.; Rawlett, A.M.; Beebe, T.P.

2011-01-01

Poly(methylmethacrylate) (PMMA)- Polyacrylonitrile (PAN) fibers were prepared using a conventional single-nozzle electrospinning technique. The as-spun fibers exhibited core-shell morphology as verified by transmission electron microscopy (TEM) and atomic force microscopy (AFM). AFM-phase and modulus mapping images of the fiber cross-section and x-ray photoelectron spectroscopy (XPS) analysis indicated PAN formed the shell and PMMA the core material. XPS, thermal gravimetric analysis (TGA), and elemental analysis were used to determine fiber compositional information. Soaking the fibers in solvent demonstrated removal of the core material, generating hollow PAN fibers. PMID:21928836

Arthritis inflammation monitored by subcutaneous millimeter wave thermography.

PubMed

Edrich, J; Smyth, C J

1978-01-01

A new technique for remote, noninvasive mapping of temperature elevations of the human joints is described; it uses the mm wave radiation emitted by the human body. A solid state switched scanner for 68 GHz is described which overcomes the depth limitations of conventional, infrared thermographs and can measure to subcutaneous depths of several mm with a temperature resolution of 0.25 degrees C. Measurements on rheumatoid arthritic knee joints are presented which show little correlation with simultaneously measured skin temperatures. Significant longterm thermographic changes induced by steroid injection indicate a potential for objective patient monitoring and development of new treatment methods.

(Full field) optical coherence tomography and applications

NASA Astrophysics Data System (ADS)

Buchroithner, Boris; Hannesschläger, Günther; Leiss-Holzinger, Elisabeth; Prylepa, Andrii; Heise, Bettina

2018-03-01

This paper illustrates specific features and use of optical coherence tomography (OCT) in the raster-scanning and in comparison in the full field version of this imaging technique. Cases for nondestructive testing are discussed alongside other application schemes. In particular monitoring time-dependent processes and probing of birefringent specimens are considered here. In the context of polymer testing birefringence mapping may often provide information about internal strain and stress states. Recent results obtained with conventional raster-scanning OCT systems, with (dual and single-shot) full field OCT configurations, and with polarization-sensitive versions of (full field) OCT are presented here.

SU-E-T-377: Inaccurate Positioning Might Introduce Significant MapCheck Calibration Error in Flatten Filter Free Beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, S; Chao, C; Columbia University, NY, NY

2014-06-01

Purpose: This study investigates the calibration error of detector sensitivity for MapCheck due to inaccurate positioning of the device, which is not taken into account by the current commercial iterative calibration algorithm. We hypothesize the calibration is more vulnerable to the positioning error for the flatten filter free (FFF) beams than the conventional flatten filter flattened beams. Methods: MapCheck2 was calibrated with 10MV conventional and FFF beams, with careful alignment and with 1cm positioning error during calibration, respectively. Open fields of 37cmx37cm were delivered to gauge the impact of resultant calibration errors. The local calibration error was modeled as amore » detector independent multiplication factor, with which propagation error was estimated with positioning error from 1mm to 1cm. The calibrated sensitivities, without positioning error, were compared between the conventional and FFF beams to evaluate the dependence on the beam type. Results: The 1cm positioning error leads to 0.39% and 5.24% local calibration error in the conventional and FFF beams respectively. After propagating to the edges of MapCheck, the calibration errors become 6.5% and 57.7%, respectively. The propagation error increases almost linearly with respect to the positioning error. The difference of sensitivities between the conventional and FFF beams was small (0.11 ± 0.49%). Conclusion: The results demonstrate that the positioning error is not handled by the current commercial calibration algorithm of MapCheck. Particularly, the calibration errors for the FFF beams are ~9 times greater than those for the conventional beams with identical positioning error, and a small 1mm positioning error might lead to up to 8% calibration error. Since the sensitivities are only slightly dependent of the beam type and the conventional beam is less affected by the positioning error, it is advisable to cross-check the sensitivities between the conventional and FFF beams to detect potential calibration errors due to inaccurate positioning. This work was partially supported by a DOD Grant No.; DOD W81XWH1010862.« less

Correlation of quantitative dual-energy computed tomography iodine maps and abdominal computed tomography perfusion measurements: are single-acquisition dual-energy computed tomography iodine maps more than a reduced-dose surrogate of conventional computed tomography perfusion?

PubMed

Stiller, Wolfram; Skornitzke, Stephan; Fritz, Franziska; Klauss, Miriam; Hansen, Jens; Pahn, Gregor; Grenacher, Lars; Kauczor, Hans-Ulrich

2015-10-01

Study objectives were the quantitative evaluation of whether conventional abdominal computed tomography (CT) perfusion measurements mathematically correlate with quantitative single-acquisition dual-energy CT (DECT) iodine concentration maps, the determination of the optimum time of acquisition for achieving maximum correlation, and the estimation of the potential for radiation exposure reduction when replacing conventional CT perfusion by single-acquisition DECT iodine concentration maps. Dual-energy CT perfusion sequences were dynamically acquired over 51 seconds (34 acquisitions every 1.5 seconds) in 24 patients with histologically verified pancreatic carcinoma using dual-source DECT at tube potentials of 80 kVp and 140 kVp. Using software developed in-house, perfusion maps were calculated from 80-kVp image series using the maximum slope model after deformable motion correction. In addition, quantitative iodine maps were calculated for each of the 34 DECT acquisitions per patient. Within a manual segmentation of the pancreas, voxel-by-voxel correlation between the perfusion map and each of the iodine maps was calculated for each patient to determine the optimum time of acquisition topt defined as the acquisition time of the iodine map with the highest correlation coefficient. Subsequently, regions of interest were placed inside the tumor and inside healthy pancreatic tissue, and correlation between mean perfusion values and mean iodine concentrations within these regions of interest at topt was calculated for the patient sample. The mean (SD) topt was 31.7 (5.4) seconds after the start of contrast agent injection. The mean (SD) perfusion values for healthy pancreatic and tumor tissues were 67.8 (26.7) mL per 100 mL/min and 43.7 (32.2) mL per 100 mL/min, respectively. At topt, the mean (SD) iodine concentrations were 2.07 (0.71) mg/mL in healthy pancreatic and 1.69 (0.98) mg/mL in tumor tissue, respectively. Overall, the correlation between perfusion values and iodine concentrations was high (0.77), with correlation of 0.89 in tumor and of 0.56 in healthy pancreatic tissue at topt. Comparing radiation exposure associated with a single DECT acquisition at topt (0.18 mSv) to that of an 80 kVp CT perfusion sequence (2.96 mSv) indicates that an average reduction of Deff by 94% could be achieved by replacing conventional CT perfusion with a single-acquisition DECT iodine concentration map. Quantitative iodine concentration maps obtained with DECT correlate well with conventional abdominal CT perfusion measurements, suggesting that quantitative iodine maps calculated from a single DECT acquisition at an organ-specific and patient-specific optimum time of acquisition might be able to replace conventional abdominal CT perfusion measurements if the time of acquisition is carefully calibrated. This could lead to large reductions of radiation exposure to the patients while offering quantitative perfusion data for diagnosis.

Molecular Imaging of Tumors Using a Quantitative T1 Mapping Technique via Magnetic Resonance Imaging

PubMed Central

Herrmann, Kelsey; Johansen, Mette L.; Craig, Sonya E.; Vincent, Jason; Howell, Michael; Gao, Ying; Lu, Lan; Erokwu, Bernadette; Agnes, Richard S.; Lu, Zheng-Rong; Pokorski, Jonathan K.; Basilion, James; Gulani, Vikas; Griswold, Mark; Flask, Chris; Brady-Kalnay, Susann M.

2015-01-01

Magnetic resonance imaging (MRI) of glioblastoma multiforme (GBM) with molecular imaging agents would allow for the specific localization of brain tumors. Prior studies using T1-weighted MR imaging demonstrated that the SBK2-Tris-(Gd-DOTA)3 molecular imaging agent labeled heterotopic xenograft models of brain tumors more intensely than non-specific contrast agents using conventional T1-weighted imaging techniques. In this study, we used a dynamic quantitative T1 mapping strategy to more objectively compare intra-tumoral retention of the SBK2-Tris-(Gd-DOTA)3 agent over time in comparison to non-targeted control agents. Our results demonstrate that the targeted SBK2-Tris-(Gd-DOTA)3 agent, a scrambled-Tris-(Gd-DOTA)3 control agent, and the non-specific clinical contrast agent Optimark™ all enhanced flank tumors of human glioma cells with similar maximal changes on T1 mapping. However, the retention of the agents differs. The non-specific agents show significant recovery within 20 min by an increase in T1 while the specific agent SBK2-Tris-(Gd-DOTA)3 is retained in the tumors and shows little recovery over 60 min. The retention effect is demonstrated by percent change in T1 values and slope calculations as well as by calculations of gadolinium concentration in tumor compared to muscle. Quantitative T1 mapping demonstrates the superior binding and retention in tumors of the SBK2-Tris-(Gd-DOTA)3 agent over time compared to the non-specific contrast agent currently in clinical use. PMID:26435847

Comparison of marginal accuracy of castings fabricated by conventional casting technique and accelerated casting technique: an in vitro study.

PubMed

Reddy, S Srikanth; Revathi, Kakkirala; Reddy, S Kranthikumar

2013-01-01

Conventional casting technique is time consuming when compared to accelerated casting technique. In this study, marginal accuracy of castings fabricated using accelerated and conventional casting technique was compared. 20 wax patterns were fabricated and the marginal discrepancy between the die and patterns were measured using Optical stereomicroscope. Ten wax patterns were used for Conventional casting and the rest for Accelerated casting. A Nickel-Chromium alloy was used for the casting. The castings were measured for marginal discrepancies and compared. Castings fabricated using Conventional casting technique showed less vertical marginal discrepancy than the castings fabricated by Accelerated casting technique. The values were statistically highly significant. Conventional casting technique produced better marginal accuracy when compared to Accelerated casting. The vertical marginal discrepancy produced by the Accelerated casting technique was well within the maximum clinical tolerance limits. Accelerated casting technique can be used to save lab time to fabricate clinical crowns with acceptable vertical marginal discrepancy.

Geological evaluation and applications of ERTS-1 imagery over Georgia

NASA Technical Reports Server (NTRS)

Pickering, S. M.; Jones, R. C.

1974-01-01

ERTS-1 70mm and 9 x 9 film negatives are being used by conventional and color enhancement methods as a tool for geologic investigation. Geologic mapping and mineral exploration by conventional methods is very difficult in Georgia. Thick soil cover and heavy vegetation cause outcrops of bed rock to be small, rare and obscure. ERTS imagery, and remote sensing in general have helped delineate: (1) major tectonic boundaries; (2) lithologic contacts; (3) foliation trends; (4) topographic lineaments; and (5) faults. The ERTS-1 MSS imagery yields the greatest amount of geologic information on the Piedomont, Blue Ridge, and Valley and Ridge Provinces of Georgia where topography is strongly controlled by the bedrock geology. ERTS imagery, and general remote sensing techniques, have provided us with a powerful tool to assist geologic research; have significantly increased the mapping efficiency of our field geologists; have shown new lineaments associated with known shear and fault zones; have delineated new structural features; have provided a tool to re-evaluate our tectonic history; have helped to locate potential ground water sources and areas of aquifer recharge; have defined areas of geologic hazards; have shown areas of heavy siltation in major reservoirs; and by its close interval repetition, have aided in monitoring surface mine reclamation activities and the environmental protection of our intricate marshland system.

Laboratory Workflow Analysis of Culture of Periprosthetic Tissues in Blood Culture Bottles.

PubMed

Peel, Trisha N; Sedarski, John A; Dylla, Brenda L; Shannon, Samantha K; Amirahmadi, Fazlollaah; Hughes, John G; Cheng, Allen C; Patel, Robin

2017-09-01

Culture of periprosthetic tissue specimens in blood culture bottles is more sensitive than conventional techniques, but the impact on laboratory workflow has yet to be addressed. Herein, we examined the impact of culture of periprosthetic tissues in blood culture bottles on laboratory workflow and cost. The workflow was process mapped, decision tree models were constructed using probabilities of positive and negative cultures drawn from our published study (T. N. Peel, B. L. Dylla, J. G. Hughes, D. T. Lynch, K. E. Greenwood-Quaintance, A. C. Cheng, J. N. Mandrekar, and R. Patel, mBio 7:e01776-15, 2016, https://doi.org/10.1128/mBio.01776-15), and the processing times and resource costs from the laboratory staff time viewpoint were used to compare periprosthetic tissues culture processes using conventional techniques with culture in blood culture bottles. Sensitivity analysis was performed using various rates of positive cultures. Annualized labor savings were estimated based on salary costs from the U.S. Labor Bureau for Laboratory staff. The model demonstrated a 60.1% reduction in mean total staff time with the adoption of tissue inoculation into blood culture bottles compared to conventional techniques (mean ± standard deviation, 30.7 ± 27.6 versus 77.0 ± 35.3 h per month, respectively; P < 0.001). The estimated annualized labor cost savings of culture using blood culture bottles was $10,876.83 (±$337.16). Sensitivity analysis was performed using various rates of culture positivity (5 to 50%). Culture in blood culture bottles was cost-effective, based on the estimated labor cost savings of $2,132.71 for each percent increase in test accuracy. In conclusion, culture of periprosthetic tissue in blood culture bottles is not only more accurate than but is also cost-saving compared to conventional culture methods. Copyright © 2017 American Society for Microbiology.

Integrating gravity and magnetic field data to delineate structurally controlled gold mineralization in the Sefwi Belt of Ghana

NASA Astrophysics Data System (ADS)

Konadu Amoah, Bernard; Dadzie, Isaac; Takyi-Kyeremeh, Kwaku

2018-08-01

Gravity and magnetic surveys were used to delineate potential gold mineralization zones in the Sefwi belt of Ghana. The study area is an intrusive dominated area that hosts pockets of small scale mining operations locally referred to as Galamsey. These Galamsey operations are not guided by a scientific approach to back the trend of gold mineralization which is conventionally mined. The study aimed at mapping lithological units, structural setting and relating Galamsey sites to delineate potential zones of gold mineralization. A Scintrex CG5 gravimeter and GEM’s Overhauser magnetometer were used for gravity and magnetic data acquisition respectively. The magnetic data were corrected and enhancing filters such as reduction to the pole (RTP), analytical signal and first vertical derivative were applied using Oasis montaj 7.1. Gravity data were also reduced to the geoid using the Oasis montaj software to produce a complete Bouguer anomaly map. The regional/residual separation technique produced a residual gravity map. The RTP and analytical signal filters from the magnetic data and residual gravity anomaly map from the gravity data helped in mapping belt type (Dixcove) Birimian granitoids and mafic intrusive unit, interpreted as gabbro. The first vertical derivative filter was useful in mapping NE/SW minor faults and crosscutting dykes largely concentrated in the belt type Birimian granitoids. All the three mapped Galamsey sites fell on a minor fault and are associated with the belt type granitoids which were used in delineating four potential zones of gold mineralization.

Evaluation of ERTS imagery for spectral geological mapping in diverse terranes of New York State

NASA Technical Reports Server (NTRS)

Isachsen, Y. W.; Fakundiny, R. H.; Forster, S. W.

1974-01-01

Linear anomalies dominate the new geological information derived from ERTS-1 imagery, total lengths now exceeding 6000 km. Experimentation with a variety of viewing techniques suggests that conventional photogeologic analyses of band 7 results in the location of more than 97 percent of all linears found. The maxima on rose diagrams for ERTS-1 anomalies correspond well with those for mapped faults and topographic lineaments, despite a difference in relative magnitudes of maxima thought due to solar illumination direction. A multiscale analysis of linears showed that single topographic linears at 1:2,500,000 became segmented at 1:1,000,000, aligned zones of shorter parallel, en echelon, or conjugate linears at 1:500,000, and still shorter linears lacking obvious alignment at 1:250,000. Visible glacial features include individual drumlins, best seen in winter imagery, drumlinoids, eskers, ice-marginal drainage channels, glacial lake shorelines and sand plains, and end moraines.

The new and computationally efficient MIL-SOM algorithm: potential benefits for visualization and analysis of a large-scale high-dimensional clinically acquired geographic data.

PubMed

Oyana, Tonny J; Achenie, Luke E K; Heo, Joon

2012-01-01

The objective of this paper is to introduce an efficient algorithm, namely, the mathematically improved learning-self organizing map (MIL-SOM) algorithm, which speeds up the self-organizing map (SOM) training process. In the proposed MIL-SOM algorithm, the weights of Kohonen's SOM are based on the proportional-integral-derivative (PID) controller. Thus, in a typical SOM learning setting, this improvement translates to faster convergence. The basic idea is primarily motivated by the urgent need to develop algorithms with the competence to converge faster and more efficiently than conventional techniques. The MIL-SOM algorithm is tested on four training geographic datasets representing biomedical and disease informatics application domains. Experimental results show that the MIL-SOM algorithm provides a competitive, better updating procedure and performance, good robustness, and it runs faster than Kohonen's SOM.

Autonomous vehicle motion control, approximate maps, and fuzzy logic

NASA Technical Reports Server (NTRS)

Ruspini, Enrique H.

1993-01-01

Progress on research on the control of actions of autonomous mobile agents using fuzzy logic is presented. The innovations described encompass theoretical and applied developments. At the theoretical level, results of research leading to the combined utilization of conventional artificial planning techniques with fuzzy logic approaches for the control of local motion and perception actions are presented. Also formulations of dynamic programming approaches to optimal control in the context of the analysis of approximate models of the real world are examined. Also a new approach to goal conflict resolution that does not require specification of numerical values representing relative goal importance is reviewed. Applied developments include the introduction of the notion of approximate map. A fuzzy relational database structure for the representation of vague and imprecise information about the robot's environment is proposed. Also the central notions of control point and control structure are discussed.

The New and Computationally Efficient MIL-SOM Algorithm: Potential Benefits for Visualization and Analysis of a Large-Scale High-Dimensional Clinically Acquired Geographic Data

PubMed Central

Oyana, Tonny J.; Achenie, Luke E. K.; Heo, Joon

2012-01-01

The objective of this paper is to introduce an efficient algorithm, namely, the mathematically improved learning-self organizing map (MIL-SOM) algorithm, which speeds up the self-organizing map (SOM) training process. In the proposed MIL-SOM algorithm, the weights of Kohonen's SOM are based on the proportional-integral-derivative (PID) controller. Thus, in a typical SOM learning setting, this improvement translates to faster convergence. The basic idea is primarily motivated by the urgent need to develop algorithms with the competence to converge faster and more efficiently than conventional techniques. The MIL-SOM algorithm is tested on four training geographic datasets representing biomedical and disease informatics application domains. Experimental results show that the MIL-SOM algorithm provides a competitive, better updating procedure and performance, good robustness, and it runs faster than Kohonen's SOM. PMID:22481977

Mediated-reality magnification for macular degeneration rehabilitation

NASA Astrophysics Data System (ADS)

Martin-Gonzalez, Anabel; Kotliar, Konstantin; Rios-Martinez, Jorge; Lanzl, Ines; Navab, Nassir

2014-10-01

Age-related macular degeneration (AMD) is a gradually progressive eye condition, which is one of the leading causes of blindness and low vision in the Western world. Prevailing optical visual aids compensate part of the lost visual function, but omitting helpful complementary information. This paper proposes an efficient magnification technique, which can be implemented on a head-mounted display, for improving vision of patients with AMD, by preserving global information of the scene. Performance of the magnification approach is evaluated by simulating central vision loss in normally sighted subjects. Visual perception was measured as a function of text reading speed and map route following speed. Statistical analysis of experimental results suggests that our magnification method improves reading speed 1.2 times and spatial orientation to find routes on a map 1.5 times compared to a conventional magnification approach, being capable to enhance peripheral vision of AMD subjects along with their life quality.

Reachability analysis of real-time systems using time Petri nets.

PubMed

Wang, J; Deng, Y; Xu, G

2000-01-01

Time Petri nets (TPNs) are a popular Petri net model for specification and verification of real-time systems. A fundamental and most widely applied method for analyzing Petri nets is reachability analysis. The existing technique for reachability analysis of TPNs, however, is not suitable for timing property verification because one cannot derive end-to-end delay in task execution, an important issue for time-critical systems, from the reachability tree constructed using the technique. In this paper, we present a new reachability based analysis technique for TPNs for timing property analysis and verification that effectively addresses the problem. Our technique is based on a concept called clock-stamped state class (CS-class). With the reachability tree generated based on CS-classes, we can directly compute the end-to-end time delay in task execution. Moreover, a CS-class can be uniquely mapped to a traditional state class based on which the conventional reachability tree is constructed. Therefore, our CS-class-based analysis technique is more general than the existing technique. We show how to apply this technique to timing property verification of the TPN model of a command and control (C2) system.

Mapping brain activity in gradient-echo functional MRI using principal component analysis

NASA Astrophysics Data System (ADS)

Khosla, Deepak; Singh, Manbir; Don, Manuel

1997-05-01

The detection of sites of brain activation in functional MRI has been a topic of immense research interest and many technique shave been proposed to this end. Recently, principal component analysis (PCA) has been applied to extract the activated regions and their time course of activation. This method is based on the assumption that the activation is orthogonal to other signal variations such as brain motion, physiological oscillations and other uncorrelated noises. A distinct advantage of this method is that it does not require any knowledge of the time course of the true stimulus paradigm. This technique is well suited to EPI image sequences where the sampling rate is high enough to capture the effects of physiological oscillations. In this work, we propose and apply tow methods that are based on PCA to conventional gradient-echo images and investigate their usefulness as tools to extract reliable information on brain activation. The first method is a conventional technique where a single image sequence with alternating on and off stages is subject to a principal component analysis. The second method is a PCA-based approach called the common spatial factor analysis technique (CSF). As the name suggests, this method relies on common spatial factors between the above fMRI image sequence and a background fMRI. We have applied these methods to identify active brain ares during visual stimulation and motor tasks. The results from these methods are compared to those obtained by using the standard cross-correlation technique. We found good agreement in the areas identified as active across all three techniques. The results suggest that PCA and CSF methods have good potential in detecting the true stimulus correlated changes in the presence of other interfering signals.

Fast imaging with inelastically scattered electrons by off-axis chromatic confocal electron microscopy.

PubMed

Zheng, Changlin; Zhu, Ye; Lazar, Sorin; Etheridge, Joanne

2014-04-25

We introduce off-axis chromatic scanning confocal electron microscopy, a technique for fast mapping of inelastically scattered electrons in a scanning transmission electron microscope without a spectrometer. The off-axis confocal mode enables the inelastically scattered electrons to be chromatically dispersed both parallel and perpendicular to the optic axis. This enables electrons with different energy losses to be separated and detected in the image plane, enabling efficient energy filtering in a confocal mode with an integrating detector. We describe the experimental configuration and demonstrate the method with nanoscale core-loss chemical mapping of silver (M4,5) in an aluminium-silver alloy and atomic scale imaging of the low intensity core-loss La (M4,5@840  eV) signal in LaB6. Scan rates up to 2 orders of magnitude faster than conventional methods were used, enabling a corresponding reduction in radiation dose and increase in the field of view. If coupled with the enhanced depth and lateral resolution of the incoherent confocal configuration, this offers an approach for nanoscale three-dimensional chemical mapping.

Evaluation of HCMM satellite data for estuarine tidal circulation patterns and thermal inertia soil moisture measurements. [Delaware Bay, Cooper River, and the Potomac River estuaries; Luverne, Minnesota, soil moisture, and water temperature of Lake Anna, Virginia

NASA Technical Reports Server (NTRS)

Wiesnet, D. R.; Mcginnis, D. F., Jr. (Principal Investigator); Matson, M.; Pritchard, J. A.

1981-01-01

Digital thermal maps of the Cooper River (SC) and the Potomac River estuaries were prepared from heat capacity mapping radiometer (HCMR) tapes. Tidal phases were correctly interpreted and verified. Synoptic surface circulation patterns were charted by location thermal fronts and water mass boundaries within the estuaries. Thermal anomalies were detected adjacent of a conventional power plant on the Potomac. Under optimum conditions, estuaries as small as the Cooper River can be monitored for generalized thermal/tidal circulation patterns by the HCMM-type IR sensors. The HCMM thermal inertia approach to estimating soil moisture at the Luverne (MN) test site was found to be unsatisfactory as a NESS operational satellite technique because of cloud cover interference. Thermal-IR data show similar structure of the Baltimore and Washington heat islands when compared to NOAA AVHRR thermal-IR data. Thermal anomalies from the warm water discharge water of a nuclear power plant were mapped in Lake Anna, Virginia.

Analysis of the characteristics appearing in LANDSAT multispectral images in the geological structural mapping of the midwestern portion of the Rio Grande do Sul shield. M.S. Thesis - 25 Mar. 1982; [Brazil

NASA Technical Reports Server (NTRS)

Parada, N. D. J. (Principal Investigator); Ohara, T.

1982-01-01

The central-western part of Rio Grande do Sul Shield was geologically mapped to test the use of MSS-LANDSAT data in the study of mineralized regions. Visual interpretation of the images a the scale of 1:500,000 consisted, in the identification and analysis of the different tonal and textural patterns in each spectral band. After the structural geologic mapping of the area, using visual interpretation techniques, the statistical data obtained were evaluated, specially data concerning size and direction of fractures. The IMAGE-100 system was used to enlarge and enhance certain imagery. The LANDSAT MSS data offer several advantages over conventional white and black aerial photographs for geological studies. Its multispectral characteristic (band 6 and false color composition of bands 4, 5 and 7 were best suitable for the study). Coverage of a large imaging area of about 35,000 sq km, giving a synoptical view, is very useful for perceiving the regional geological setting.

Identification of Characteristic Macromolecules of Escherichia coli Genotypes by Atomic Force Microscope Nanoscale Mechanical Mapping

NASA Astrophysics Data System (ADS)

Chang, Alice Chinghsuan; Liu, Bernard Haochih

2018-02-01

The categorization of microbial strains is conventionally based on the molecular method, and seldom are the morphological characteristics in the bacterial strains studied. In this research, we revealed the macromolecular structures of the bacterial surface via AFM mechanical mapping, whose resolution was not only determined by the nanoscale tip size but also the mechanical properties of the specimen. This technique enabled the nanoscale study of membranous structures of microbial strains with simple specimen preparation and flexible working environments, which overcame the multiple restrictions in electron microscopy and label-enable biochemical analytical methods. The characteristic macromolecules located among cellular surface were considered as surface layer proteins and were found to be specific to the Escherichia coli genotypes, from which the averaged molecular sizes were characterized with diameters ranging from 38 to 66 nm, and the molecular shapes were kidney-like or round. In conclusion, the surface macromolecular structures have unique characteristics that link to the E. coli genotype, which suggests that the genomic effects on cellular morphologies can be rapidly identified using AFM mechanical mapping. [Figure not available: see fulltext.

Optimal and fast E/B separation with a dual messenger field

NASA Astrophysics Data System (ADS)

Kodi Ramanah, Doogesh; Lavaux, Guilhem; Wandelt, Benjamin D.

2018-05-01

We adapt our recently proposed dual messenger algorithm for spin field reconstruction and showcase its efficiency and effectiveness in Wiener filtering polarized cosmic microwave background (CMB) maps. Unlike conventional preconditioned conjugate gradient (PCG) solvers, our preconditioner-free technique can deal with high-resolution joint temperature and polarization maps with inhomogeneous noise distributions and arbitrary mask geometries with relative ease. Various convergence diagnostics illustrate the high quality of the dual messenger reconstruction. In contrast, the PCG implementation fails to converge to a reasonable solution for the specific problem considered. The implementation of the dual messenger method is straightforward and guarantees numerical stability and convergence. We show how the algorithm can be modified to generate fluctuation maps, which, combined with the Wiener filter solution, yield unbiased constrained signal realizations, consistent with observed data. This algorithm presents a pathway to exact global analyses of high-resolution and high-sensitivity CMB data for a statistically optimal separation of E and B modes. It is therefore relevant for current and next-generation CMB experiments, in the quest for the elusive primordial B-mode signal.

A general framework of TOPSIS method for integration of airborne geophysics, satellite imagery, geochemical and geological data

NASA Astrophysics Data System (ADS)

Abedi, Maysam; Norouzi, Gholam-Hossain

2016-04-01

This work presents the promising application of three variants of TOPSIS method (namely the conventional, adjusted and modified versions) as a straightforward knowledge-driven technique in multi criteria decision making processes for data fusion of a broad exploratory geo-dataset in mineral potential/prospectivity mapping. The method is implemented to airborne geophysical data (e.g. potassium radiometry, aeromagnetic and frequency domain electromagnetic data), surface geological layers (fault and host rock zones), extracted alteration layers from remote sensing satellite imagery data, and five evidential attributes from stream sediment geochemical data. The central Iranian volcanic-sedimentary belt in Kerman province at the SE of Iran that is embedded in the Urumieh-Dokhtar Magmatic Assemblage arc (UDMA) is chosen to integrate broad evidential layers in the region of prospect. The studied area has high potential of ore mineral occurrences especially porphyry copper/molybdenum and the generated mineral potential maps aim to outline new prospect zones for further investigation in future. Two evidential layers of the downward continued aeromagnetic data and its analytic signal filter are prepared to be incorporated in fusion process as geophysical plausible footprints of the porphyry type mineralization. The low values of the apparent resistivity layer calculated from the airborne frequency domain electromagnetic data are also used as an electrical criterion in this investigation. Four remote sensing evidential layers of argillic, phyllic, propylitic and hydroxyl alterations were extracted from ASTER images in order to map the altered areas associated with porphyry type deposits, whilst the ETM+ satellite imagery data were used as well to map iron oxide layer. Since potassium alteration is generally the mainstay of porphyry ore mineralization, the airborne potassium radiometry data was used. The geochemical layers of Cu/B/Pb/Zn elements and the first component of PCA analysis were considered as powerful traces to prepare final maps. The conventional, adjusted and modified variants of the TOPSIS method produced three mineral potential maps, in which the outputs indicate adequately matching of high potential zones with previous working and active mines in the region.

Development of predictive mapping techniques for soil survey and salinity mapping

NASA Astrophysics Data System (ADS)

Elnaggar, Abdelhamid A.

Conventional soil maps represent a valuable source of information about soil characteristics, however they are subjective, very expensive, and time-consuming to prepare. Also, they do not include explicit information about the conceptual mental model used in developing them nor information about their accuracy, in addition to the error associated with them. Decision tree analysis (DTA) was successfully used in retrieving the expert knowledge embedded in old soil survey data. This knowledge was efficiently used in developing predictive soil maps for the study areas in Benton and Malheur Counties, Oregon and accessing their consistency. A retrieved soil-landscape model from a reference area in Harney County was extrapolated to develop a preliminary soil map for the neighboring unmapped part of Malheur County. The developed map had a low prediction accuracy and only a few soil map units (SMUs) were predicted with significant accuracy, mostly those shallow SMUs that have either a lithic contact with the bedrock or developed on a duripan. On the other hand, the developed soil map based on field data was predicted with very high accuracy (overall was about 97%). Salt-affected areas of the Malheur County study area are indicated by their high spectral reflectance and they are easily discriminated from the remote sensing data. However, remote sensing data fails to distinguish between the different classes of soil salinity. Using the DTA method, five classes of soil salinity were successfully predicted with an overall accuracy of about 99%. Moreover, the calculated area of salt-affected soil was overestimated when mapped using remote sensing data compared to that predicted by using DTA. Hence, DTA could be a very helpful approach in developing soil survey and soil salinity maps in more objective, effective, less-expensive and quicker ways based on field data.

Advances in Spectral-Spatial Classification of Hyperspectral Images

NASA Technical Reports Server (NTRS)

Fauvel, Mathieu; Tarabalka, Yuliya; Benediktsson, Jon Atli; Chanussot, Jocelyn; Tilton, James C.

2012-01-01

Recent advances in spectral-spatial classification of hyperspectral images are presented in this paper. Several techniques are investigated for combining both spatial and spectral information. Spatial information is extracted at the object (set of pixels) level rather than at the conventional pixel level. Mathematical morphology is first used to derive the morphological profile of the image, which includes characteristics about the size, orientation and contrast of the spatial structures present in the image. Then the morphological neighborhood is defined and used to derive additional features for classification. Classification is performed with support vector machines using the available spectral information and the extracted spatial information. Spatial post-processing is next investigated to build more homogeneous and spatially consistent thematic maps. To that end, three presegmentation techniques are applied to define regions that are used to regularize the preliminary pixel-wise thematic map. Finally, a multiple classifier system is defined to produce relevant markers that are exploited to segment the hyperspectral image with the minimum spanning forest algorithm. Experimental results conducted on three real hyperspectral images with different spatial and spectral resolutions and corresponding to various contexts are presented. They highlight the importance of spectral-spatial strategies for the accurate classification of hyperspectral images and validate the proposed methods.

Dissolution enhancement of tadalafil by liquisolid technique.

PubMed

Lu, Mei; Xing, Haonan; Yang, Tianzhi; Yu, Jiankun; Yang, Zhen; Sun, Yanping; Ding, Pingtian

2017-02-01

This study aimed to enhance the dissolution of tadalafil, a poorly water-soluble drug by applying liquisolid technique. The effects of two critical formulation variables, namely drug concentration (17.5% and 35%, w/w) and excipients ratio (10, 15 and 20) on dissolution rates were investigated. Pre-compression tests, including particle size distribution, flowability determination, Fourier transform infrared (FT-IR), differential scanning calorimetry (DSC), X-ray diffractometry (XRD) and scanning electron microscopy (SEM), were carried out to investigate the mechanism of dissolution enhancement. Tadalafil liquisolid tablets were prepared and their quality control tests, dissolution study, contact angle measurement, Raman mapping, and storage stability test were performed. The results suggested that all the liquisolid tablets exhibited significantly higher dissolution rates than the conventional tablets and pure tadalafil. FT-IR spectrum reflected no drug-excipient interactions. DSC and XRD studies indicated reduction in crystallinity of tadalafil, which was further confirmed by SEM and Raman mapping outcomes. The contact angle measurement demonstrated obvious increase in wetting property. Taken together, the reduction of particle size and crystallinity, and the improvement of wettability were the main mechanisms for the enhanced dissolution rate. No significant changes were observed in drug crystallinity and dissolution behavior after storage based on XRD, SEM and dissolution results.

Spatial Mapping of Structural and Connectional Imaging Data for the Developing Human Brain with Diffusion Tensor Imaging

PubMed Central

Ouyang, Austin; Jeon, Tina; Sunkin, Susan M.; Pletikos, Mihovil; Sedmak, Goran; Sestan, Nenad; Lein, Ed S.; Huang, Hao

2014-01-01

During human brain development from fetal stage to adulthood, the white matter (WM) tracts undergo dramatic changes. Diffusion tensor imaging (DTI), a widely used magnetic resonance imaging (MRI) modality, offers insight into the dynamic changes of WM fibers as these fibers can be noninvasively traced and three-dimensionally (3D) reconstructed with DTI tractography. The DTI and conventional T1 weighted MRI images also provide sufficient cortical anatomical details for mapping the cortical regions of interests (ROIs). In this paper, we described basic concepts and methods of DTI techniques that can be used to trace major WM tracts noninvasively from fetal brain of 14 postconceptional weeks (pcw) to adult brain. We applied these techniques to acquire DTI data and trace, reconstruct and visualize major WM tracts during development. After categorizing major WM fiber bundles into five unique functional tract groups, namely limbic, brain stem, projection, commissural and association tracts, we revealed formation and maturation of these 3D reconstructed WM tracts of the developing human brain. The structural and connectional imaging data offered by DTI provides the anatomical backbone of transcriptional atlas of the developing human brain. PMID:25448302

Automatic correction of echo-planar imaging (EPI) ghosting artifacts in real-time interactive cardiac MRI using sensitivity encoding.

PubMed

Kim, Yoon-Chul; Nielsen, Jon-Fredrik; Nayak, Krishna S

2008-01-01

To develop a method that automatically corrects ghosting artifacts due to echo-misalignment in interleaved gradient-echo echo-planar imaging (EPI) in arbitrary oblique or double-oblique scan planes. An automatic ghosting correction technique was developed based on an alternating EPI acquisition and the phased-array ghost elimination (PAGE) reconstruction method. The direction of k-space traversal is alternated at every temporal frame, enabling lower temporal-resolution ghost-free coil sensitivity maps to be dynamically estimated. The proposed method was compared with conventional one-dimensional (1D) phase correction in axial, oblique, and double-oblique scan planes in phantom and cardiac in vivo studies. The proposed method was also used in conjunction with two-fold acceleration. The proposed method with nonaccelerated acquisition provided excellent suppression of ghosting artifacts in all scan planes, and was substantially more effective than conventional 1D phase correction in oblique and double-oblique scan planes. The feasibility of real-time reconstruction using the proposed technique was demonstrated in a scan protocol with 3.1-mm spatial and 60-msec temporal resolution. The proposed technique with nonaccelerated acquisition provides excellent ghost suppression in arbitrary scan orientations without a calibration scan, and can be useful for real-time interactive imaging, in which scan planes are frequently changed with arbitrary oblique orientations.

Glow discharge sources for atomic and molecular analyses

NASA Astrophysics Data System (ADS)

Storey, Andrew Patrick

Two types of glow discharges were used and characterized for chemical analysis. The flowing atmospheric pressure afterglow (FAPA) source, based on a helium glow discharge (GD), was utilized to analyze samples with molecular mass spectrometry. A second GD, operated at reduced pressure in argon, was employed to map the elemental composition of a solid surface with novel optical detection systems, enabling new applications and perspectives for GD emission spectrometry. Like many plasma-based ambient desorption-ionization sources being used around the world, the FAPA requires a supply of helium to operate effectively. With increased pressures on global helium supply and pricing, the use of an interrupted stream of helium for analysis was explored for vapor and solid samples. In addition to the mass spectra generated by the FAPA source, schlieren imaging and infrared thermography were employed to map the behavior of the source and its surroundings under the altered conditions. Additionally, a new annular microplasma variation of the FAPA source was developed and characterized. A spectroscopic imaging system that utilized an adjustable-tilt interference filter was used to map the elemental composition of a sample surface by glow discharge emission spectroscopy. This apparatus was compared to other GD imaging techniques for mapping elemental surface composition. The wide bandpass filter resulted in significant spectral interferences that could be partially overcome with chemometric data processing. Because time-resolved GD emission spectroscopy can provide fine depth-profiling measurements, a natural extension of GD imaging would be its application to three-dimensional characterization of samples. However, the simultaneous cathodic sputtering that occur across the sample results in a sampling process that is not completely predictable. These issues are frequently encountered when laterally varied samples are explored with glow discharge imaging techniques. These insights are described with respect to their consequences for both imaging and conventional GD spectroscopic techniques.

3D topology of orientation columns in visual cortex revealed by functional optical coherence tomography.

PubMed

Nakamichi, Yu; Kalatsky, Valery A; Watanabe, Hideyuki; Sato, Takayuki; Rajagopalan, Uma Maheswari; Tanifuji, Manabu

2018-04-01

Orientation tuning is a canonical neuronal response property of six-layer visual cortex that is encoded in pinwheel structures with center orientation singularities. Optical imaging of intrinsic signals enables us to map these surface two-dimensional (2D) structures, whereas lack of appropriate techniques has not allowed us to visualize depth structures of orientation coding. In the present study, we performed functional optical coherence tomography (fOCT), a technique capable of acquiring a 3D map of the intrinsic signals, to study the topology of orientation coding inside the cat visual cortex. With this technique, for the first time, we visualized columnar assemblies in orientation coding that had been predicted from electrophysiological recordings. In addition, we found that the columnar structures were largely distorted around pinwheel centers: center singularities were not rigid straight lines running perpendicularly to the cortical surface but formed twisted string-like structures inside the cortex that turned and extended horizontally through the cortex. Looping singularities were observed with their respective termini accessing the same cortical surface via clockwise and counterclockwise orientation pinwheels. These results suggest that a 3D topology of orientation coding cannot be fully anticipated from 2D surface measurements. Moreover, the findings demonstrate the utility of fOCT as an in vivo mesoscale imaging method for mapping functional response properties of cortex in the depth axis. NEW & NOTEWORTHY We used functional optical coherence tomography (fOCT) to visualize three-dimensional structure of the orientation columns with millimeter range and micrometer spatial resolution. We validated vertically elongated columnar structure in iso-orientation domains. The columnar structure was distorted around pinwheel centers. An orientation singularity formed a string with tortuous trajectories inside the cortex and connected clockwise and counterclockwise pinwheel centers in the surface orientation map. The results were confirmed by comparisons with conventional optical imaging and electrophysiological recordings.

Metabolic Mapping: Quantitative Enzyme Cytochemistry and Histochemistry to Determine the Activity of Dehydrogenases in Cells and Tissues.

PubMed

Molenaar, Remco J; Khurshed, Mohammed; Hira, Vashendriya V V; Van Noorden, Cornelis J F

2018-05-26

Altered cellular metabolism is a hallmark of many diseases, including cancer, cardiovascular diseases and infection. The metabolic motor units of cells are enzymes and their activity is heavily regulated at many levels, including the transcriptional, mRNA stability, translational, post-translational and functional level. This complex regulation means that conventional quantitative or imaging assays, such as quantitative mRNA experiments, Western Blots and immunohistochemistry, yield incomplete information regarding the ultimate activity of enzymes, their function and/or their subcellular localization. Quantitative enzyme cytochemistry and histochemistry (i.e., metabolic mapping) show in-depth information on in situ enzymatic activity and its kinetics, function and subcellular localization in an almost true-to-nature situation. We describe a protocol to detect the activity of dehydrogenases, which are enzymes that perform redox reactions to reduce cofactors such as NAD(P) + and FAD. Cells and tissue sections are incubated in a medium that is specific for the enzymatic activity of one dehydrogenase. Subsequently, the dehydrogenase that is the subject of investigation performs its enzymatic activity in its subcellular site. In a chemical reaction with the reaction medium, this ultimately generates blue-colored formazan at the site of the dehydrogenase's activity. The formazan's absorbance is therefore a direct measure of the dehydrogenase's activity and can be quantified using monochromatic light microscopy and image analysis. The quantitative aspect of this protocol enables researchers to draw statistical conclusions from these assays. Besides observational studies, this technique can be used for inhibition studies of specific enzymes. In this context, studies benefit from the true-to-nature advantages of metabolic mapping, giving in situ results that may be physiologically more relevant than in vitro enzyme inhibition studies. In all, metabolic mapping is an indispensable technique to study metabolism at the cellular or tissue level. The technique is easy to adopt, provides in-depth, comprehensive and integrated metabolic information and enables rapid quantitative analysis.

Respiration-induced movement correlation for synchronous noninvasive renal cancer surgery.

PubMed

Abhilash, Rakkunedeth H; Chauhan, Sunita

2012-07-01

Noninvasive surgery (NIS), such as high-intensity focused ultrasound (HIFU)-based ablation or radiosurgery, is used for treating tumors and cancers in various parts of the body. The soft tissue targets (usually organs) deform and move as a result of physiological processes such as respiration. Moreover, other deformations induced during surgery by changes in patient position, changes in physical properties caused by repeated exposures and uncertainties resulting from cavitation also occur. In this paper, we present a correlation-based movement prediction technique to address respiration-induced movement of the urological organs while targeting through extracorporeal trans-abdominal route access. Among other organs, kidneys are worst affected during respiratory cycles, with significant three-dimensional displacements observed on the order of 20 mm. Remote access to renal targets such as renal carcinomas and cysts during noninvasive surgery, therefore, requires a tightly controlled real-time motion tracking and quantitative estimate for compensation routine to synchronize the energy source(s) for precise energy delivery to the intended regions. The correlation model finds a mapping between the movement patterns of external skin markers placed on the abdominal access window and the internal movement of the targeted kidney. The coarse estimate of position is then fine-tuned using the Adaptive Neuro-Fuzzy Inference System (ANFIS), thereby achieving a nonlinear mapping. The technical issues involved in this tracking scheme are threefold: the model must have sufficient accuracy in mapping the movement pattern; there must be an image-based tracking scheme to provide the organ position within allowable system latency; and the processing delay resulting from modeling and tracking must be within the achievable prediction horizon to accommodate the latency in the therapeutic delivery system. The concept was tested on ultrasound image sequences collected from 20 healthy volunteers. The results indicate that the modeling technique can be practically integrated into an image-guided noninvasive robotic surgical system with an indicative targeting accuracy of more than 94%. A comparative analysis showed the superiority of this technique over conventional linear mapping and modelfree blind search techniques.

The efficacy of the 'mind map' study technique.

PubMed

Farrand, Paul; Hussain, Fearzana; Hennessy, Enid

2002-05-01

To examine the effectiveness of using the 'mind map' study technique to improve factual recall from written information. To obtain baseline data, subjects completed a short test based on a 600-word passage of text prior to being randomly allocated to form two groups: 'self-selected study technique' and 'mind map'. After a 30-minute interval the self-selected study technique group were exposed to the same passage of text previously seen and told to apply existing study techniques. Subjects in the mind map group were trained in the mind map technique and told to apply it to the passage of text. Recall was measured after an interfering task and a week later. Measures of motivation were taken. Barts and the London School of Medicine and Dentistry, University of London. 50 second- and third-year medical students. Recall of factual material improved for both the mind map and self-selected study technique groups at immediate test compared with baseline. However this improvement was only robust after a week for those in the mind map group. At 1 week, the factual knowledge in the mind map group was greater by 10% (adjusting for baseline) (95% CI -1% to 22%). However motivation for the technique used was lower in the mind map group; if motivation could have been made equal in the groups, the improvement with mind mapping would have been 15% (95% CI 3% to 27%). Mind maps provide an effective study technique when applied to written material. However before mind maps are generally adopted as a study technique, consideration has to be given towards ways of improving motivation amongst users.

Quantification of both the area-at-risk and acute myocardial infarct size in ST-segment elevation myocardial infarction using T1-mapping.

PubMed

Bulluck, Heerajnarain; Hammond-Haley, Matthew; Fontana, Marianna; Knight, Daniel S; Sirker, Alex; Herrey, Anna S; Manisty, Charlotte; Kellman, Peter; Moon, James C; Hausenloy, Derek J

2017-08-01

A comprehensive cardiovascular magnetic resonance (CMR) in reperfused ST-segment myocardial infarction (STEMI) patients can be challenging to perform and can be time-consuming. We aimed to investigate whether native T1-mapping can accurately delineate the edema-based area-at-risk (AAR) and post-contrast T1-mapping and synthetic late gadolinium (LGE) images can quantify MI size at 1.5 T. Conventional LGE imaging and T2-mapping could then be omitted, thereby shortening the scan duration. Twenty-eight STEMI patients underwent a CMR scan at 1.5 T, 3 ± 1 days following primary percutaneous coronary intervention. The AAR was quantified using both native T1 and T2-mapping. MI size was quantified using conventional LGE, post-contrast T1-mapping and synthetic magnitude-reconstructed inversion recovery (MagIR) LGE and synthetic phase-sensitive inversion recovery (PSIR) LGE, derived from the post-contrast T1 maps. Native T1-mapping performed as well as T2-mapping in delineating the AAR (41.6 ± 11.9% of the left ventricle [% LV] versus 41.7 ± 12.2% LV, P = 0.72; R 2 0.97; ICC 0.986 (0.969-0.993); bias -0.1 ± 4.2% LV). There were excellent correlation and inter-method agreement with no bias, between MI size by conventional LGE, synthetic MagIR LGE (bias 0.2 ± 2.2%LV, P = 0.35), synthetic PSIR LGE (bias 0.4 ± 2.2% LV, P = 0.060) and post-contrast T1-mapping (bias 0.3 ± 1.8% LV, P = 0.10). The mean scan duration was 58 ± 4 min. Not performing T2 mapping (6 ± 1 min) and conventional LGE (10 ± 1 min) would shorten the CMR study by 15-20 min. T1-mapping can accurately quantify both the edema-based AAR (using native T1 maps) and acute MI size (using post-contrast T1 maps) in STEMI patients without major cardiovascular risk factors. This approach would shorten the duration of a comprehensive CMR study without significantly compromising on data acquisition and would obviate the need to perform T2 maps and LGE imaging.

Mapping Inhibitory Neuronal Circuits by Laser Scanning Photostimulation

PubMed Central

Ikrar, Taruna; Olivas, Nicholas D.; Shi, Yulin; Xu, Xiangmin

2011-01-01

Inhibitory neurons are crucial to cortical function. They comprise about 20% of the entire cortical neuronal population and can be further subdivided into diverse subtypes based on their immunochemical, morphological, and physiological properties1-4. Although previous research has revealed much about intrinsic properties of individual types of inhibitory neurons, knowledge about their local circuit connections is still relatively limited3,5,6. Given that each individual neuron's function is shaped by its excitatory and inhibitory synaptic input within cortical circuits, we have been using laser scanning photostimulation (LSPS) to map local circuit connections to specific inhibitory cell types. Compared to conventional electrical stimulation or glutamate puff stimulation, LSPS has unique advantages allowing for extensive mapping and quantitative analysis of local functional inputs to individually recorded neurons3,7-9. Laser photostimulation via glutamate uncaging selectively activates neurons perisomatically, without activating axons of passage or distal dendrites, which ensures a sub-laminar mapping resolution. The sensitivity and efficiency of LSPS for mapping inputs from many stimulation sites over a large region are well suited for cortical circuit analysis. Here we introduce the technique of LSPS combined with whole-cell patch clamping for local inhibitory circuit mapping. Targeted recordings of specific inhibitory cell types are facilitated by use of transgenic mice expressing green fluorescent proteins (GFP) in limited inhibitory neuron populations in the cortex3,10, which enables consistent sampling of the targeted cell types and unambiguous identification of the cell types recorded. As for LSPS mapping, we outline the system instrumentation, describe the experimental procedure and data acquisition, and present examples of circuit mapping in mouse primary somatosensory cortex. As illustrated in our experiments, caged glutamate is activated in a spatially restricted region of the brain slice by UV laser photolysis; simultaneous voltage-clamp recordings allow detection of photostimulation-evoked synaptic responses. Maps of either excitatory or inhibitory synaptic input to the targeted neuron are generated by scanning the laser beam to stimulate hundreds of potential presynaptic sites. Thus, LSPS enables the construction of detailed maps of synaptic inputs impinging onto specific types of inhibitory neurons through repeated experiments. Taken together, the photostimulation-based technique offers neuroscientists a powerful tool for determining the functional organization of local cortical circuits. PMID:22006064

Use of multispectral Ikonos imagery for discriminating between conventional and conservation agricultural tillage practices

USGS Publications Warehouse

Vina, Andres; Peters, Albert J.; Ji, Lei

2003-01-01

There is a global concern about the increase in atmospheric concentrations of greenhouse gases. One method being discussed to encourage greenhouse gas mitigation efforts is based on a trading system whereby carbon emitters can buy effective mitigation efforts from farmers implementing conservation tillage practices. These practices sequester carbon from the atmosphere, and such a trading system would require a low-cost and accurate method of verification. Remote sensing technology can offer such a verification technique. This paper is focused on the use of standard image processing procedures applied to a multispectral Ikonos image, to determine whether it is possible to validate that farmers have complied with agreements to implement conservation tillage practices. A principal component analysis (PCA) was performed in order to isolate image variance in cropped fields. Analyses of variance (ANOVA) statistical procedures were used to evaluate the capability of each Ikonos band and each principal component to discriminate between conventional and conservation tillage practices. A logistic regression model was implemented on the principal component most effective in discriminating between conventional and conservation tillage, in order to produce a map of the probability of conventional tillage. The Ikonos imagery, in combination with ground-reference information, proved to be a useful tool for verification of conservation tillage practices.

Application of photogrammetry for analysis of occlusal contacts.

PubMed

Shigeta, Yuko; Hirabayashi, Rio; Ikawa, Tomoko; Kihara, Takuya; Ando, Eriko; Hirai, Shinya; Fukushima, Shunji; Ogawa, Takumi

2013-04-01

The conventional 2D-analysis methods for occlusal contacts provided limited information on tooth morphology. This present study aims to detect 3D positional information of occlusal contacts from 2D-photos via photogrammetry. We propose an image processing solution for analysis of occlusal contacts and facets via the black silicone method and a photogrammetric technique. The occlusal facets were reconstructed from a 2D-photograph data-set of inter-occlusal records into a 3D image via photogrammetry. The configuration of the occlusal surface was reproduced with polygons. In addition, the textures of the occlusal contacts were mapped to each polygon. DIFFERENCE FROM CONVENTIONAL METHODS: Constructing occlusal facets with 3D polygons from 2D-photos with photogrammetry was a defining characteristic of this image processing technique. It allowed us to better observe findings of the black silicone method. Compared with conventional 3D analysis using a 3D scanner, our 3D models did not reproduce the detail of the anatomical configuration. However, by merging the findings of the inter-occlusal record, the deformation of mandible and the displacement of periodontal ligaments under occlusal force were reflected in our model. EFFECT OR PERFORMANCE: Through the use of polygons in the conversion of 2D images to 3D images, we were able to define the relation between the location and direction of the occlusal contacts and facets, which was difficult to detect via conventional methods. Through our method of making a 3D polygon model, the findings of inter-occlusal records which reflected the jaw/teeth behavior under occlusal force could be observed 3-dimensionally. Copyright © 2012 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

Using 3D visualization and seismic attributes to improve structural and stratigraphic resolution of reservoirs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kerr, J.; Jones, G.L.

1996-01-01

Recent advances in hardware and software have given the interpreter and engineer new ways to view 3D seismic data and well bore information. Recent papers have also highlighted the use of various statistics and seismic attributes. By combining new 3D rendering technologies with recent trends in seismic analysis, the interpreter can improve the structural and stratigraphic resolution of hydrocarbon reservoirs. This paper gives several examples using 3D visualization to better define both the structural and stratigraphic aspects of several different structural types from around the world. Statistics, 3D visualization techniques and rapid animation are used to show complex faulting andmore » detailed channel systems. These systems would be difficult to map using either 2D or 3D data with conventional interpretation techniques.« less

Using 3D visualization and seismic attributes to improve structural and stratigraphic resolution of reservoirs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kerr, J.; Jones, G.L.

1996-12-31

Recent advances in hardware and software have given the interpreter and engineer new ways to view 3D seismic data and well bore information. Recent papers have also highlighted the use of various statistics and seismic attributes. By combining new 3D rendering technologies with recent trends in seismic analysis, the interpreter can improve the structural and stratigraphic resolution of hydrocarbon reservoirs. This paper gives several examples using 3D visualization to better define both the structural and stratigraphic aspects of several different structural types from around the world. Statistics, 3D visualization techniques and rapid animation are used to show complex faulting andmore » detailed channel systems. These systems would be difficult to map using either 2D or 3D data with conventional interpretation techniques.« less

mapKITE: a New Paradigm for Simultaneous Aerial and Terrestrial Geodata Acquisition and Mapping

NASA Astrophysics Data System (ADS)

Molina, P.; Blázquez, M.; Sastre, J.; Colomina, I.

2016-06-01

We introduce a new mobile, simultaneous terrestrial and aerial, geodata collection and post-processing method: mapKITE. By combining two mapping technologies such as terrestrial mobile mapping and unmanned aircraft aerial mapping, geodata are simultaneously acquired from air and ground. More in detail, a mapKITE geodata acquisition system consists on an unmanned aircraft and a terrestrial vehicle, which hosts the ground control station. By means of a real-time navigation system on the terrestrial vehicle, real-time waypoints are sent to the aircraft from the ground. By doing so, the aircraft is linked to the terrestrial vehicle through a "virtual tether," acting as a "mapping kite." In the article, we entail the concept of mapKITE as well as the various technologies and techniques involved, from aircraft guidance and navigation based on IMU and GNSS, optical cameras for mapping and tracking, sensor orientation and calibration, etc. Moreover, we report of a new measurement introduced in mapKITE, that is, point-and-scale photogrammetric measurements [of image coordinates and scale] for optical targets of known size installed on the ground vehicle roof. By means of accurate posteriori trajectory determination of the terrestrial vehicle, mapKITE benefits then from kinematic ground control points which are photogrametrically observed by point-and-scale measures. Initial results for simulated configurations show that these measurements added to the usual Integrated Sensor Orientation ones reduce or even eliminate the need of conventional ground control points -therefore, lowering mission costs- and enable selfcalibration of the unmanned aircraft interior orientation parameters in corridor configurations, in contrast to the situation of traditional corridor configurations. Finally, we report about current developments of the first mapKITE prototype, developed under the European Union Research and Innovation programme Horizon 2020. The first mapKITE mission will be held at the BCN Drone Center (Collsuspina, Moià, Spain) in mid 2016.

Adapting line integral convolution for fabricating artistic virtual environment

NASA Astrophysics Data System (ADS)

Lee, Jiunn-Shyan; Wang, Chung-Ming

2003-04-01

Vector field occurs not only extensively in scientific applications but also in treasured art such as sculptures and paintings. Artist depicts our natural environment stressing valued directional feature besides color and shape information. Line integral convolution (LIC), developed for imaging vector field in scientific visualization, has potential of producing directional image. In this paper we present several techniques of exploring LIC techniques to generate impressionistic images forming artistic virtual environment. We take advantage of directional information given by a photograph, and incorporate many investigations to the work including non-photorealistic shading technique and statistical detail control. In particular, the non-photorealistic shading technique blends cool and warm colors into the photograph to imitate artists painting convention. Besides, we adopt statistical technique controlling integral length according to image variance to preserve details. Furthermore, we also propose method for generating a series of mip-maps, which revealing constant strokes under multi-resolution viewing and achieving frame coherence in an interactive walkthrough system. The experimental results show merits of emulating satisfyingly and computing efficiently, as a consequence, relying on the proposed technique successfully fabricates a wide category of non-photorealistic rendering (NPR) application such as interactive virtual environment with artistic perception.

Non-destructive investigation of thermoplastic reinforced composites

DOE PAGES

Hassen, Ahmed; Taheri, Hossein; Vaidya, Uday

2016-05-09

This paper studies various manufacturing defects in glass fiber/Polypropylene (PP) composite parts and their methods of detection. Foreign Object Inclusion (FOI) of different shapes, sizes, and materials were placed in a glass fiber/PP panel made by compression molding. The paper aims to characterize the fiber orientation and fiber related defects such as fiber waviness in the composite specimen. Comprehensive investigation for different Non Destructive Evaluation (NDE) techniques, namely X-ray radiography and Ultrasonic Testing (UT) techniques to trace and characterize the embedded defects and the composite texture are presented. Conventional X-ray radiography successfully identified the fiber orientation in two dimension (2-D)more » plane; however, information for the sample depth was not captured. The radiography techniques showed low relative errors for the defect size measurements (maximum error was below 9.5%) when compared to the ultrasonic techniques. Ultrasonic techniques were able to map all the embedded artificial defects. Phase Array (PA) ultrasonic technique was able to precisely locate the FOI in the glass fiber/PP specimen. Nerveless, the shape and size of the defects were not accurately determined due to the high signal attenuation and distortion characteristics of the E-glass fiber.« less

Digital Versus Conventional Impressions in Fixed Prosthodontics: A Review.

PubMed

Ahlholm, Pekka; Sipilä, Kirsi; Vallittu, Pekka; Jakonen, Minna; Kotiranta, Ulla

2018-01-01

To conduct a systematic review to evaluate the evidence of possible benefits and accuracy of digital impression techniques vs. conventional impression techniques. Reports of digital impression techniques versus conventional impression techniques were systematically searched for in the following databases: Cochrane Central Register of Controlled Trials, PubMed, and Web of Science. A combination of controlled vocabulary, free-text words, and well-defined inclusion and exclusion criteria guided the search. Digital impression accuracy is at the same level as conventional impression methods in fabrication of crowns and short fixed dental prostheses (FDPs). For fabrication of implant-supported crowns and FDPs, digital impression accuracy is clinically acceptable. In full-arch impressions, conventional impression methods resulted in better accuracy compared to digital impressions. Digital impression techniques are a clinically acceptable alternative to conventional impression methods in fabrication of crowns and short FDPs. For fabrication of implant-supported crowns and FDPs, digital impression systems also result in clinically acceptable fit. Digital impression techniques are faster and can shorten the operation time. Based on this study, the conventional impression technique is still recommended for full-arch impressions. © 2016 by the American College of Prosthodontists.

Floodplain Mapping for the Continental United States Using Machine Learning Techniques and Watershed Characteristics

NASA Astrophysics Data System (ADS)

Jafarzadegan, K.; Merwade, V.; Saksena, S.

2017-12-01

Using conventional hydrodynamic methods for floodplain mapping in large-scale and data-scarce regions is problematic due to the high cost of these methods, lack of reliable data and uncertainty propagation. In this study a new framework is proposed to generate 100-year floodplains for any gauged or ungauged watershed across the United States (U.S.). This framework uses Flood Insurance Rate Maps (FIRMs), topographic, climatic and land use data which are freely available for entire U.S. for floodplain mapping. The framework consists of three components, including a Random Forest classifier for watershed classification, a Probabilistic Threshold Binary Classifier (PTBC) for generating the floodplains, and a lookup table for linking the Random Forest classifier to the PTBC. The effectiveness and reliability of the proposed framework is tested on 145 watersheds from various geographical locations in the U.S. The validation results show that around 80 percent of total watersheds are predicted well, 14 percent have acceptable fit and less than five percent are predicted poorly compared to FIRMs. Another advantage of this framework is its ability in generating floodplains for all small rivers and tributaries. Due to the high accuracy and efficiency of this framework, it can be used as a preliminary decision making tool to generate 100-year floodplain maps for data-scarce regions and all tributaries where hydrodynamic methods are difficult to use.

Resting-State Functional Magnetic Resonance Imaging for Language Preoperative Planning

PubMed Central

Branco, Paulo; Seixas, Daniela; Deprez, Sabine; Kovacs, Silvia; Peeters, Ronald; Castro, São L.; Sunaert, Stefan

2016-01-01

Functional magnetic resonance imaging (fMRI) is a well-known non-invasive technique for the study of brain function. One of its most common clinical applications is preoperative language mapping, essential for the preservation of function in neurosurgical patients. Typically, fMRI is used to track task-related activity, but poor task performance and movement artifacts can be critical limitations in clinical settings. Recent advances in resting-state protocols open new possibilities for pre-surgical mapping of language potentially overcoming these limitations. To test the feasibility of using resting-state fMRI instead of conventional active task-based protocols, we compared results from fifteen patients with brain lesions while performing a verb-to-noun generation task and while at rest. Task-activity was measured using a general linear model analysis and independent component analysis (ICA). Resting-state networks were extracted using ICA and further classified in two ways: manually by an expert and by using an automated template matching procedure. The results revealed that the automated classification procedure correctly identified language networks as compared to the expert manual classification. We found a good overlay between task-related activity and resting-state language maps, particularly within the language regions of interest. Furthermore, resting-state language maps were as sensitive as task-related maps, and had higher specificity. Our findings suggest that resting-state protocols may be suitable to map language networks in a quick and clinically efficient way. PMID:26869899

Temporal reliability of ultra-high field resting-state MRI for single-subject sensorimotor and language mapping.

PubMed

Branco, Paulo; Seixas, Daniela; Castro, São Luís

2018-03-01

Resting-state fMRI is a well-suited technique to map functional networks in the brain because unlike task-based approaches it requires little collaboration from subjects. This is especially relevant in clinical settings where a number of subjects cannot comply with task demands. Previous studies using conventional scanner fields have shown that resting-state fMRI is able to map functional networks in single subjects, albeit with moderate temporal reliability. Ultra-high resolution (7T) imaging provides higher signal-to-noise ratio and better spatial resolution and is thus well suited to assess the temporal reliability of mapping results, and to determine if resting-state fMRI can be applied in clinical decision making including preoperative planning. We used resting-state fMRI at ultra-high resolution to examine whether the sensorimotor and language networks are reliable over time - same session and one week after. Resting-state networks were identified for all subjects and sessions with good accuracy. Both networks were well delimited within classical regions of interest. Mapping was temporally reliable at short and medium time-scales as demonstrated by high values of overlap in the same session and one week after for both networks. Results were stable independently of data quality metrics and physiological variables. Taken together, these findings provide strong support for the suitability of ultra-high field resting-state fMRI mapping at the single-subject level. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Dynamic multi-coil technique (DYNAMITE) shimming for echo-planar imaging of the human brain at 7 Tesla.

PubMed

Juchem, Christoph; Umesh Rudrapatna, S; Nixon, Terence W; de Graaf, Robin A

2015-01-15

Gradient-echo echo-planar imaging (EPI) is the primary method of choice in functional MRI and other methods relying on fast MRI to image brain activation and connectivity. However, the high susceptibility of EPI towards B0 magnetic field inhomogeneity poses serious challenges. Conventional magnetic field shimming with low-order spherical harmonic (SH) functions is capable of compensating shallow field distortions, but performs poorly for global brain shimming or on specific areas with strong susceptibility-induced B0 distortions such as the prefrontal cortex (PFC). Excellent B0 homogeneity has been demonstrated recently in the human brain at 7 Tesla with the DYNAmic Multi-coIl TEchnique (DYNAMITE) for magnetic field shimming (J Magn Reson (2011) 212:280-288). Here, we report the benefits of DYNAMITE shimming for multi-slice EPI and T2* mapping. A standard deviation of 13Hz was achieved for the residual B0 distribution in the human brain at 7 Tesla with DYNAMITE shimming and was 60% lower compared to conventional shimming that employs static zero through third order SH shapes. The residual field inhomogeneity with SH shimming led to an average 8mm shift at acquisition parameters commonly used for fMRI and was reduced to 1.5-3mm with DYNAMITE shimming. T2* values obtained from the prefrontal and temporal cortices with DYNAMITE shimming were 10-50% longer than those measured with SH shimming. The reduction of the confounding macroscopic B0 field gradients with DYNAMITE shimming thereby promises improved access to the relevant microscopic T2* effects. The combination of high spatial resolution and DYNAMITE shimming allows largely artifact-free EPI and T2* mapping throughout the brain, including prefrontal and temporal lobe areas. DYNAMITE shimming is expected to critically benefit a wide range of MRI applications that rely on excellent B0 magnetic field conditions including EPI-based fMRI to study various cognitive processes and assessing large-scale brain connectivity in vivo. As such, DYNAMITE shimming has the potential to replace conventional SH shim systems in human MR scanners. Copyright © 2014 Elsevier Inc. All rights reserved.

Dynamic Multi-Coil Technique (DYNAMITE) Shimming for Echo-Planar Imaging of the Human Brain at 7 Tesla

PubMed Central

Juchem, Christoph; Rudrapatna, S. Umesh; Nixon, Terence W.; de Graaf, Robin A.

2014-01-01

Gradient-echo echo-planar imaging (EPI) is the primary method of choice in functional MRI and other methods relying on fast MRI to image brain activation and connectivity. However, the high susceptibility of EPI towards B0 magnetic field inhomogeneity poses serious challenges. Conventional magnetic field shimming with low-order spherical harmonic (SH) functions is capable of compensating shallow field distortions, but performs poorly for global brain shimming or on specific areas with strong susceptibility-induced B0 distortions such as the prefrontal cortex (PFC). Excellent B0 homogeneity has been demonstrated recently in the human brain at 7 Tesla with the DYNAmic Multi-coIl TEchnique (DYNAMITE) for magnetic field shimming (Juchem et al., J Magn Reson (2011) 212:280-288). Here, we report the benefits of DYNAMITE shimming for multi-slice EPI and T2* mapping. A standard deviation of 13 Hz was achieved for the residual B0 distribution in the human brain at 7 Tesla with DYNAMITE shimming and was 60% lower compared to conventional shimming that employs static zero through third order SH shapes. The residual field inhomogeneity with SH shimming led to an average 8 mm shift at acquisition parameters commonly used for fMRI and was reduced to 1.5-3 mm with DYNAMITE shimming. T2* values obtained from the prefrontal and temporal cortices with DYNAMITE shimming were 10-50% longer than those measured with SH shimming. The reduction of the confounding macroscopic B0 field gradients with DYNAMITE shimming thereby promises improved access to the relevant microscopic T2* effects. The combination of high spatial resolution and DYNAMITE shimming allows largely artifact-free EPI and T2* mapping throughout the brain, including prefrontal and temporal lobe areas. DYNAMITE shimming is expected to critically benefit a wide range of MRI applications that rely on excellent B0 magnetic field conditions including EPI-based fMRI to study various cognitive processes and assessing large-scale brain connectivity in vivo. As such, DYNAMITE shimming has the potential to replace conventional SH shim systems in human MR scanners. PMID:25462795

Evaluation of marginal gap of Ni-Cr copings made with conventional and accelerated casting techniques.

PubMed

Tannamala, Pavan Kumar; Azhagarasan, Nagarasampatti Sivaprakasam; Shankar, K Chitra

2013-01-01

Conventional casting techniques following the manufacturers' recommendations are time consuming. Accelerated casting techniques have been reported, but their accuracy with base metal alloys has not been adequately studied. We measured the vertical marginal gap of nickel-chromium copings made by conventional and accelerated casting techniques and determined the clinical acceptability of the cast copings in this study. Experimental design, in vitro study, lab settings. Ten copings each were cast by conventional and accelerated casting techniques. All copings were identical, only their mold preparation schedules differed. Microscopic measurements were recorded at ×80 magnification on the perpendicular to the axial wall at four predetermined sites. The marginal gap values were evaluated by paired t test. The mean marginal gap by conventional technique (34.02 μm) is approximately 10 μm lesser than that of accelerated casting technique (44.62 μm). As the P value is less than 0.0001, there is highly significant difference between the two techniques with regard to vertical marginal gap. The accelerated casting technique is time saving and the marginal gap measured was within the clinically acceptable limits and could be an alternative to time-consuming conventional techniques.

Transcranial passive acoustic mapping with hemispherical sparse arrays using CT-based skull-specific aberration corrections: a simulation study

PubMed Central

Jones, Ryan M.; O’Reilly, Meaghan A.; Hynynen, Kullervo

2013-01-01

The feasibility of transcranial passive acoustic mapping with hemispherical sparse arrays (30 cm diameter, 16 to 1372 elements, 2.48 mm receiver diameter) using CT-based aberration corrections was investigated via numerical simulations. A multi-layered ray acoustic transcranial ultrasound propagation model based on CT-derived skull morphology was developed. By incorporating skull-specific aberration corrections into a conventional passive beamforming algorithm (Norton and Won 2000 IEEE Trans. Geosci. Remote Sens. 38 1337–43), simulated acoustic source fields representing the emissions from acoustically-stimulated microbubbles were spatially mapped through three digitized human skulls, with the transskull reconstructions closely matching the water-path control images. Image quality was quantified based on main lobe beamwidths, peak sidelobe ratio, and image signal-to-noise ratio. The effects on the resulting image quality of the source’s emission frequency and location within the skull cavity, the array sparsity and element configuration, the receiver element sensitivity, and the specific skull morphology were all investigated. The system’s resolution capabilities were also estimated for various degrees of array sparsity. Passive imaging of acoustic sources through an intact skull was shown possible with sparse hemispherical imaging arrays. This technique may be useful for the monitoring and control of transcranial focused ultrasound (FUS) treatments, particularly non-thermal, cavitation-mediated applications such as FUS-induced blood-brain barrier disruption or sonothrombolysis, for which no real-time monitoring technique currently exists. PMID:23807573

T1ρ MR Imaging of Human Musculoskeletal System

PubMed Central

Wang, Ligong; Regatte, Ravinder R.

2014-01-01

Magnetic resonance imaging (MRI) offers the direct visualization of human musculoskeletal (MSK) system, especially all diarthrodial tissues including cartilage, bone, menisci, ligaments, tendon, hip, synovium etc. Conventional MR imaging techniques based on T1- and T2-weighted, proton density (PD) contrast are inconclusive in quantifying early biochemically degenerative changes in MSK system in general and articular cartilage in particular. In recent years, quantitative MR parameter mapping techniques have been used to quantify the biochemical changes in articular cartilage with a special emphasis on evaluating joint injury, cartilage degeneration, and soft tissue repair. In this article, we will focus on cartilage biochemical composition, basic principles of T1ρ MR imaging, implementation of T1ρ pulse sequences, biochemical validation, and summarize the potential applications of T1ρ MR imaging technique in MSK diseases including osteoarthritis (OA), anterior cruciate ligament (ACL) injury, and knee joint repair. Finally, we will also review the potential advantages, challenges, and future prospects of T1ρ MR imaging for widespread clinical translation. PMID:24935818

Learning directed acyclic graphs from large-scale genomics data.

PubMed

Nikolay, Fabio; Pesavento, Marius; Kritikos, George; Typas, Nassos

2017-09-20

In this paper, we consider the problem of learning the genetic interaction map, i.e., the topology of a directed acyclic graph (DAG) of genetic interactions from noisy double-knockout (DK) data. Based on a set of well-established biological interaction models, we detect and classify the interactions between genes. We propose a novel linear integer optimization program called the Genetic-Interactions-Detector (GENIE) to identify the complex biological dependencies among genes and to compute the DAG topology that matches the DK measurements best. Furthermore, we extend the GENIE program by incorporating genetic interaction profile (GI-profile) data to further enhance the detection performance. In addition, we propose a sequential scalability technique for large sets of genes under study, in order to provide statistically significant results for real measurement data. Finally, we show via numeric simulations that the GENIE program and the GI-profile data extended GENIE (GI-GENIE) program clearly outperform the conventional techniques and present real data results for our proposed sequential scalability technique.

T₁ρ MRI of human musculoskeletal system.

PubMed

Wang, Ligong; Regatte, Ravinder R

2015-03-01

Magnetic resonance imaging (MRI) offers the direct visualization of the human musculoskeletal (MSK) system, especially all diarthrodial tissues including cartilage, bone, menisci, ligaments, tendon, hip, synovium, etc. Conventional MRI techniques based on T1 - and T2 -weighted, proton density (PD) contrast are inconclusive in quantifying early biochemically degenerative changes in MSK system in general and articular cartilage in particular. In recent years, quantitative MR parameter mapping techniques have been used to quantify the biochemical changes in articular cartilage, with a special emphasis on evaluating joint injury, cartilage degeneration, and soft tissue repair. In this article we focus on cartilage biochemical composition, basic principles of T1ρ MRI, implementation of T1ρ pulse sequences, biochemical validation, and summarize the potential applications of the T1ρ MRI technique in MSK diseases including osteoarthritis (OA), anterior cruciate ligament (ACL) injury, and knee joint repair. Finally, we also review the potential advantages, challenges, and future prospects of T1ρ MRI for widespread clinical translation. © 2014 Wiley Periodicals, Inc.

Analysis of microarray leukemia data using an efficient MapReduce-based K-nearest-neighbor classifier.

PubMed

Kumar, Mukesh; Rath, Nitish Kumar; Rath, Santanu Kumar

2016-04-01

Microarray-based gene expression profiling has emerged as an efficient technique for classification, prognosis, diagnosis, and treatment of cancer. Frequent changes in the behavior of this disease generates an enormous volume of data. Microarray data satisfies both the veracity and velocity properties of big data, as it keeps changing with time. Therefore, the analysis of microarray datasets in a small amount of time is essential. They often contain a large amount of expression, but only a fraction of it comprises genes that are significantly expressed. The precise identification of genes of interest that are responsible for causing cancer are imperative in microarray data analysis. Most existing schemes employ a two-phase process such as feature selection/extraction followed by classification. In this paper, various statistical methods (tests) based on MapReduce are proposed for selecting relevant features. After feature selection, a MapReduce-based K-nearest neighbor (mrKNN) classifier is also employed to classify microarray data. These algorithms are successfully implemented in a Hadoop framework. A comparative analysis is done on these MapReduce-based models using microarray datasets of various dimensions. From the obtained results, it is observed that these models consume much less execution time than conventional models in processing big data. Copyright © 2016 Elsevier Inc. All rights reserved.

A particle swarm optimized kernel-based clustering method for crop mapping from multi-temporal polarimetric L-band SAR observations

NASA Astrophysics Data System (ADS)

Tamiminia, Haifa; Homayouni, Saeid; McNairn, Heather; Safari, Abdoreza

2017-06-01

Polarimetric Synthetic Aperture Radar (PolSAR) data, thanks to their specific characteristics such as high resolution, weather and daylight independence, have become a valuable source of information for environment monitoring and management. The discrimination capability of observations acquired by these sensors can be used for land cover classification and mapping. The aim of this paper is to propose an optimized kernel-based C-means clustering algorithm for agriculture crop mapping from multi-temporal PolSAR data. Firstly, several polarimetric features are extracted from preprocessed data. These features are linear polarization intensities, and several statistical and physical based decompositions such as Cloude-Pottier, Freeman-Durden and Yamaguchi techniques. Then, the kernelized version of hard and fuzzy C-means clustering algorithms are applied to these polarimetric features in order to identify crop types. The kernel function, unlike the conventional partitioning clustering algorithms, simplifies the non-spherical and non-linearly patterns of data structure, to be clustered easily. In addition, in order to enhance the results, Particle Swarm Optimization (PSO) algorithm is used to tune the kernel parameters, cluster centers and to optimize features selection. The efficiency of this method was evaluated by using multi-temporal UAVSAR L-band images acquired over an agricultural area near Winnipeg, Manitoba, Canada, during June and July in 2012. The results demonstrate more accurate crop maps using the proposed method when compared to the classical approaches, (e.g. 12% improvement in general). In addition, when the optimization technique is used, greater improvement is observed in crop classification, e.g. 5% in overall. Furthermore, a strong relationship between Freeman-Durden volume scattering component, which is related to canopy structure, and phenological growth stages is observed.

Cartography for lunar exploration: 2008 status and mission plans

USGS Publications Warehouse

Kirk, R.L.; Archinal, B.A.; Gaddis, L.R.; Rosiek, M.R.; Chen, Jun; Jiang, Jie; Nayak, Shailesh

2008-01-01

The initial spacecraft exploration of the Moon in the 1960s-70s yielded extensive data, primarily in the form of film and television images, which were used to produce a large number of hardcopy maps by conventional techniques. A second era of exploration, beginning in the early 1990s, has produced digital data including global multispectral imagery and altimetry, from which a new generation of digital map products tied to a rapidly evolving global control network has been made. Efforts are also underway to scan the earlier hardcopy maps for online distribution and to digitize the film images so that modern processing techniques can be used to make high-resolution digital terrain models (DTMs) and image mosaics consistent with the current global control. The pace of lunar exploration is accelerating dramatically, with as many as eight new missions already launched or planned for the current decade. These missions, of which the most important for cartography are SMART-1 (Europe), Kaguya/SELENE (Japan), Chang'e-1 (China), Chandrayaan-1 (India), and Lunar Reconnaissance Orbiter (USA), will return a volume of data exceeding that of all previous lunar and planetary missions combined. Framing and scanner camera images, including multispectral and stereo data, hyperspectral images, synthetic aperture radar (SAR) images, and laser altimetry will all be collected, including, in most cases, multiple data sets of each type. Substantial advances in international standardization and cooperation, development of new and more efficient data processing methods, and availability of resources for processing and archiving will all be needed if the next generation of missions are to fulfill their potential for high-precision mapping of the Moon in support of subsequent exploration and scientific investigation.

Comparative Analysis Between Computed and Conventional Inferior Alveolar Nerve Block Techniques.

PubMed

Araújo, Gabriela Madeira; Barbalho, Jimmy Charles Melo; Dias, Tasiana Guedes de Souza; Santos, Thiago de Santana; Vasconcellos, Ricardo José de Holanda; de Morais, Hécio Henrique Araújo

2015-11-01

The aim of this randomized, double-blind, controlled trial was to compare the computed and conventional inferior alveolar nerve block techniques in symmetrically positioned inferior third molars. Both computed and conventional anesthetic techniques were performed in 29 healthy patients (58 surgeries) aged between 18 and 40 years. The anesthetic of choice was 2% lidocaine with 1: 200,000 epinephrine. The Visual Analogue Scale assessed the pain variable after anesthetic infiltration. Patient satisfaction was evaluated using the Likert Scale. Heart and respiratory rates, mean time to perform technique, and the need for additional anesthesia were also evaluated. Pain variable means were higher for the conventional technique as compared with computed, 3.45 ± 2.73 and 2.86 ± 1.96, respectively, but no statistically significant differences were found (P > 0.05). Patient satisfaction showed no statistically significant differences. The average computed technique runtime and the conventional were 3.85 and 1.61 minutes, respectively, showing statistically significant differences (P <0.001). The computed anesthetic technique showed lower mean pain perception, but did not show statistically significant differences when contrasted to the conventional technique.

Modelling and mapping long-term risks due to reactive nitrogen effects: an overview of LRTAP convention activities.

PubMed

Spranger, T; Hettelingh, J-P; Slootweg, J; Posch, M

2008-08-01

Long-range transboundary air pollution has caused severe environmental effects in Europe. European air pollution abatement policy, in the framework of the UNECE Convention on Long-range Transboundary Air Pollution (LRTAP Convention) and the European Union Clean Air for Europe (CAFE) programme, has used critical loads and their exceedances by atmospheric deposition to design emission abatement targets and strategies. The LRTAP Convention International Cooperative Programme on Modelling and Mapping Critical Loads and Levels and Air Pollution Effects, Risks and Trends (ICP M&M) generates European critical loads datasets to enable this work. Developing dynamic nitrogen flux models and using them for a prognosis and assessment of nitrogen effects remains a challenge. Further research is needed on links between nitrogen deposition effects, climate change, and biodiversity.

Habitat mapping using hyperspectral images in the vicinity of Hekla volcano in Iceland

NASA Astrophysics Data System (ADS)

Vilmundardóttir, Olga K.; Sigurmundsson, Friðþór S.; Pedersen, Gro B. M.; Falco, Nicola; Rustowicz, Rose; Gísladóttir, Guðrún; Benediktsson, Jón A.

2016-04-01

Hekla, one of the most active volcanoes in Iceland, has created a diverse volcanic landscape with lava flows, hyaloclastite and tephra fields. The variety of geological formations and different times of formation create diverse vegetation within Hekla's vicinity. The region is subjected to extensive loss of vegetation cover and soil erosion due to human utilization of woodlands and ongoing sheep grazing. The eolian activity and frequent tephra deposition has created vast areas of sparse vegetation cover. Over the 20th century, many activities have centered on preventing further loss of vegetated land and restoring ecosystems. The benefit of these activities is now noticeable in the increased vegetation and woodland cover although erosion is still active within the area. For mapping and monitoring this highly dynamic environment remote sensing techniques are extremely useful. One of the principal goals of the project 'Environmental Mapping and Monitoring of Iceland with Remote Sensing' (EMMIRS) is to use hyperspectral images and LiDAR data to classify and map the vegetation within the Hekla area. The data was collected in an aerial survey in summer 2015 by the Natural Environment Research Council (NERC), UK. The habitat type classification, currently being developed at the Icelandic Institute of Natural History and follows the structure of the EUNIS classification system, will be used for classifying the vegetation. The habitat map created by this new technique's outcome will be compared to the existent vegetation maps made by the conventional vegetation mapping method and the multispectral image classification techniques. In the field, vegetation cover, soil properties and spectral reflectance were measured within different habitat types. Special emphasis was on collecting data on vegetation and soil in the historical lavas from Hekla for assessing habitats forming over the millennia. A lava-chronosequence was established by measuring vegetation and soil in lavas formed in 2000, 1991, 1980-81, 1970, 1947, 1913, 1878, 1845, 1766-68, 1693, 1554, 1389-90, 1300, and 1206, representing surfaces of age 15-809 years. Results showed that vegetation cover established rather quickly on the lavas where mosses and lichens already created a full cover after 24 years. The cover remained stable and mosses were the dominant plant group for centuries, unless where tephra fall had occurred or where eolian deposition prevailed. The colonization of vascular plants on the lava was slow except at sites of eolian deposition and tephra fall. Dwarf shrubs and shrubs were rare or even absent on the lavas formed during the last century but their cover increased with increasing age of the lava fields. The older lava fields featured a variety of vegetation classes, indicating different rates and pathways of succession depending on altitude, proximity to eolian sources, land use and other factors. The many similarities yet big contrasts in the habitats featured within the Hekla region pose a challenge for creating a habitat map of the area, testing the potency of the hyperspectral data and classification techniques to the fullest.

Black-blood native T1 mapping: Blood signal suppression for reduced partial voluming in the myocardium.

PubMed

Weingärtner, Sebastian; Meßner, Nadja M; Zöllner, Frank G; Akçakaya, Mehmet; Schad, Lothar R

2017-08-01

To study the feasibility of black-blood contrast in native T 1 mapping for reduction of partial voluming at the blood-myocardium interface. A saturation pulse prepared heart-rate-independent inversion recovery (SAPPHIRE) T 1 mapping sequence was combined with motion-sensitized driven-equilibrium (MSDE) blood suppression for black-blood T 1 mapping at 3 Tesla. Phantom scans were performed to assess the T 1 time accuracy. In vivo black-blood and conventional SAPPHIRE T 1 mapping was performed in eight healthy subjects and analyzed for T 1 times, precision, and inter- and intraobserver variability. Furthermore, manually drawn regions of interest (ROIs) in all T 1 maps were dilated and eroded to analyze the dependence of septal T 1 times on the ROI thickness. Phantom results and in vivo myocardial T 1 times show comparable accuracy with black-blood compared to conventional SAPPHIRE (in vivo: black-blood: 1562 ± 56 ms vs. conventional: 1583 ± 58 ms, P = 0.20); Using black-blood SAPPHIRE precision was significantly lower (standard deviation: 133.9 ± 24.6 ms vs. 63.1 ± 6.4 ms, P < .0001), and blood T 1 time measurement was not possible. Significantly increased interobserver interclass correlation coefficient (ICC) (0.996 vs. 0.967, P = 0.011) and similar intraobserver ICC (0.979 vs. 0.939, P = 0.11) was obtained with the black-blood sequence. Conventional SAPPHIRE showed strong dependence on the ROI thickness (R 2 = 0.99). No such trend was observed using the black-blood approach (R 2 = 0.29). Black-blood SAPPHIRE successfully eliminates partial voluming at the blood pool in native myocardial T 1 mapping while providing accurate T 1 times, albeit at a reduced precision. Magn Reson Med 78:484-493, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

Multilayer apparent magnetization mapping approach and its application in mineral exploration

NASA Astrophysics Data System (ADS)

Guo, L.; Meng, X.; Chen, Z.

2016-12-01

Apparent magnetization mapping is a technique to estimate magnetization distribution in the subsurface from the observed magnetic data. It has been applied for geologic mapping and mineral exploration for decades. Apparent magnetization mapping usually models the magnetic layer as a collection of vertical, juxtaposed prisms in both horizontal directions, whose top and bottom surfaces are assumed to be horizontal or variable-depth, and then inverts or deconvolves the magnetic anomalies in the space or frequency domain to determine the magnetization of each prism. The conventional mapping approaches usually assume that magnetic sources contain no remanent magnetization. However, such assumptions are not always valid in mineral exploration of metallic ores. In this case, the negligence of the remanence will result in large geologic deviation or the occurrence of negative magnetization. One alternate strategy is to transform the observed magnetic anomalies into some quantities that are insensitive or weakly sensitive to the remanence and then subsequently to perform inversion on these quantities, without needing any a priori information about remanent magnetization. Such kinds of quantities include the amplitude of the magnetic total field anomaly (AMA), and the normalized magnetic source strength (NSS). Here, we present a space-domain inversion approach for multilayer magnetization mapping based on the AMA for reducing effects of remanence. In the real world, magnetization usually varies vertically in the subsurface. If we use only one-layer model for mapping, the result is simply vertical superposition of different magnetization distributions. Hence, a multi-layer model for mapping would be a more realistic approach. We test the approach on the real data from a metallic deposit area in North China. The results demonstrated that our approach is feasible and produces considerable magnetization distribution from top layer to bottom layer in the subsurface.

Dual-contrast agent photon-counting computed tomography of the heart: initial experience.

PubMed

Symons, Rolf; Cork, Tyler E; Lakshmanan, Manu N; Evers, Robert; Davies-Venn, Cynthia; Rice, Kelly A; Thomas, Marvin L; Liu, Chia-Ying; Kappler, Steffen; Ulzheimer, Stefan; Sandfort, Veit; Bluemke, David A; Pourmorteza, Amir

2017-08-01

To determine the feasibility of dual-contrast agent imaging of the heart using photon-counting detector (PCD) computed tomography (CT) to simultaneously assess both first-pass and late enhancement of the myocardium. An occlusion-reperfusion canine model of myocardial infarction was used. Gadolinium-based contrast was injected 10 min prior to PCD CT. Iodinated contrast was infused immediately prior to PCD CT, thus capturing late gadolinium enhancement as well as first-pass iodine enhancement. Gadolinium and iodine maps were calculated using a linear material decomposition technique and compared to single-energy (conventional) images. PCD images were compared to in vivo and ex vivo magnetic resonance imaging (MRI) and histology. For infarct versus remote myocardium, contrast-to-noise ratio (CNR) was maximal on late enhancement gadolinium maps (CNR 9.0 ± 0.8, 6.6 ± 0.7, and 0.4 ± 0.4, p < 0.001 for gadolinium maps, single-energy images, and iodine maps, respectively). For infarct versus blood pool, CNR was maximum for iodine maps (CNR 11.8 ± 1.3, 3.8 ± 1.0, and 1.3 ± 0.4, p < 0.001 for iodine maps, gadolinium maps, and single-energy images, respectively). Combined first-pass iodine and late gadolinium maps allowed quantitative separation of blood pool, scar, and remote myocardium. MRI and histology analysis confirmed accurate PCD CT delineation of scar. Simultaneous multi-contrast agent cardiac imaging is feasible with photon-counting detector CT. These initial proof-of-concept results may provide incentives to develop new k-edge contrast agents, to investigate possible interactions between multiple simultaneously administered contrast agents, and to ultimately bring them to clinical practice.

Simultaneous Measurement of T2 and Apparent Diffusion Coefficient (T2+ADC) in the Heart With Motion-Compensated Spin Echo Diffusion-Weighted Imaging

PubMed Central

Aliotta, Eric; Moulin, Kévin; Zhang, Zhaohuan; Ennis, Daniel B.

2018-01-01

Purpose To evaluate a technique for simultaneous quantitative T2 and apparent diffusion coefficient (ADC) mapping in the heart (T2+ADC) using spin echo (SE) diffusion-weighted imaging (DWI). Theory and Methods T2 maps from T2+ADC were compared with single-echo SE in phantoms and with T2-prepared (T2-prep) balanced steady-state free precession (bSSFP) in healthy volunteers. ADC maps from T2+ADC were compared with conventional DWI in phantoms and in vivo. T2+ADC was also demonstrated in a patient with acute myocardial infarction (MI). Results Phantom T2 values from T2+ADC were closer to a single-echo SE reference than T2-prep bSSFP (−2.3 ± 6.0% vs 22.2 ± 16.3%; P < 0.01), and ADC values were in excellent agreement with DWI (0.28 ± 0.4%). In volunteers, myocardial T2 values from T2+ADC were significantly shorter than T2-prep bSSFP (35.8 ± 3.1 vs 46.8 ± 3.8 ms; P < 0.01); myocardial ADC was not significantly (N.S.) different between T2+ADC and conventional motion-compensated DWI (1.39 ± 0.18 vs 1.38 ± 0.18 mm2/ms; P = N.S.). In the patient, T2 and ADC were both significantly elevated in the infarct compared with remote myocardium (T2: 40.4 ± 7.6 vs 56.8 ± 22.0; P < 0.01; ADC: 1.47 ± 0.59 vs 1.65 ± 0.65 mm2/ms; P < 0.01). Conclusion T2+ADC generated coregistered, free-breathing T2 and ADC maps in healthy volunteers and a patient with acute MI with no cost in accuracy, precision, or scan time compared with DWI. PMID:28516485

Ohio River main stem study - The role of geographic information systems and remote sensing in flood damage assessments

NASA Technical Reports Server (NTRS)

Edwardo, H. A.; Moulis, F. R.; Merry, C. J.; Mckim, H. L.; Kerber, A. G.; Miller, M. A.

1985-01-01

The Pittsburgh District, Corps of Engineers, has conducted feasibility analyses of various procedures for performing flood damage assessments along the main stem of the Ohio River. Procedures using traditional, although highly automated, techniques and those based on geographic information systems have been evaluated at a test site, the City of New Martinsville, Wetzel County, WV. The flood damage assessments of the test site developed from an automated, conventional structure-by-structure appraisal served as the ground truth data set. A geographic information system was developed for the test site which includes data on hydraulic reach, ground and reference flood elevations, and land use/cover. Damage assessments were made using land use mapping developed from an exhaustive field inspection of each tax parcel. This ground truth condition was considered to provide the best comparison of flood damages to the conventional approach. Also, four land use/cover data sets were developed from Thematic Mapper Simulator (TMS) and Landsat-4 Thematic Mapper (TM) data. One of these was also used to develop a damage assessment of the test site. This paper presents the comparative absolute and relative accuracies of land use/cover mapping and flood damage assessments, and the recommended role of geographic information systems aided by remote sensing for conducting flood damage assessments and updates along the main stem of the Ohio River.

Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data.

PubMed

Goodwin, Cody R; Sherrod, Stacy D; Marasco, Christina C; Bachmann, Brian O; Schramm-Sapyta, Nicole; Wikswo, John P; McLean, John A

2014-07-01

A metabolic system is composed of inherently interconnected metabolic precursors, intermediates, and products. The analysis of untargeted metabolomics data has conventionally been performed through the use of comparative statistics or multivariate statistical analysis-based approaches; however, each falls short in representing the related nature of metabolic perturbations. Herein, we describe a complementary method for the analysis of large metabolite inventories using a data-driven approach based upon a self-organizing map algorithm. This workflow allows for the unsupervised clustering, and subsequent prioritization of, correlated features through Gestalt comparisons of metabolic heat maps. We describe this methodology in detail, including a comparison to conventional metabolomics approaches, and demonstrate the application of this method to the analysis of the metabolic repercussions of prolonged cocaine exposure in rat sera profiles.

Validation of a novel mapping system and utility for mapping complex atrial tachycardias.

PubMed

Honarbakhsh, S; Hunter, R J; Dhillon, G; Ullah, W; Keating, E; Providencia, R; Chow, A; Earley, M J; Schilling, R J

2018-03-01

This study sought to validate a novel wavefront mapping system utilizing whole-chamber basket catheters (CARTOFINDER, Biosense Webster). The system was validated in terms of (1) mapping atrial-paced beats and (2) mapping complex wavefront patterns in atrial tachycardia (AT). Patients undergoing catheter ablation for AT and persistent AF were included. A 64-pole-basket catheter was used to acquire unipolar signals that were processed by CARTOFINDER mapping system to generate dynamic wavefront propagation maps. The left atrium was paced from four sites to demonstrate focal activation. ATs were mapped with the mechanism confirmed by conventional mapping, entrainment, and response to ablation. Twenty-two patients were included in the study (16 with AT and 6 with AF initially who terminated to AT during ablation). In total, 172 maps were created with the mapping system. It correctly identified atrial-pacing sites in all paced maps. It accurately mapped 9 focal/microreentrant and 18 macroreentrant ATs both in the left and right atrium. A third and fourth observer independently identified the sites of atrial pacing and the AT mechanism from the CARTOFINDER maps, while being blinded to the conventional activation maps. This novel mapping system was effectively validated by mapping focal activation patterns from atrial-paced beats. The system was also effective in mapping complex wavefront patterns in a range of ATs in patients with scarred atria. The system may therefore be of practical use in the mapping and ablation of AT and could have potential for mapping wavefront activations in AF. © 2018 Wiley Periodicals, Inc.

Digital Mapping Techniques '11–12 workshop proceedings

USGS Publications Warehouse

Soller, David R.

2014-01-01

At these meetings, oral and poster presentations and special discussion sessions emphasized: (1) methods for creating and publishing map products (here, "publishing" includes Web-based release); (2) field data capture software and techniques, including the use of LiDAR; (3) digital cartographic techniques; (4) migration of digital maps into ArcGIS Geodatabase formats; (5) analytical GIS techniques; and (6) continued development of the National Geologic Map Database.

Facial recognition using multisensor images based on localized kernel eigen spaces.

PubMed

Gundimada, Satyanadh; Asari, Vijayan K

2009-06-01

A feature selection technique along with an information fusion procedure for improving the recognition accuracy of a visual and thermal image-based facial recognition system is presented in this paper. A novel modular kernel eigenspaces approach is developed and implemented on the phase congruency feature maps extracted from the visual and thermal images individually. Smaller sub-regions from a predefined neighborhood within the phase congruency images of the training samples are merged to obtain a large set of features. These features are then projected into higher dimensional spaces using kernel methods. The proposed localized nonlinear feature selection procedure helps to overcome the bottlenecks of illumination variations, partial occlusions, expression variations and variations due to temperature changes that affect the visual and thermal face recognition techniques. AR and Equinox databases are used for experimentation and evaluation of the proposed technique. The proposed feature selection procedure has greatly improved the recognition accuracy for both the visual and thermal images when compared to conventional techniques. Also, a decision level fusion methodology is presented which along with the feature selection procedure has outperformed various other face recognition techniques in terms of recognition accuracy.

Clinical equivalence assessment of T2 synthesized pediatric brain magnetic resonance imaging.

PubMed

Kerleroux, Basile; Kober, Tobias; Hilbert, Tom; Serru, Maxence; Sirinelli, Dominique; Morel, Baptiste

2018-05-04

Automated synthetic magnetic resonance imaging (MRI) provides qualitative, weighted image contrasts as well as quantitative information from one scan and is well-suited for various applications such as analysis of white matter disorders. However, the synthesized contrasts have been poorly evaluated in pediatric applications. The purpose of this study was to compare the image quality of synthetic T2 to conventional turbo spin echo (TSE) T2 in pediatric brain MRI. This was a mono-center prospective study. Synthetic and conventional MRI acquisitions at 1.5 Tesla were performed for each patient during the same session using a prototype accelerated T2 mapping sequence package (TA synthetic =3:07min, TA conventional =2:33min). Image sets were blindly and randomly analyzed by pediatric neuro-radiologists. Global image quality, morphologic legibility of standard structures and artifacts were assessed using a 4-point Likert scale. Inter-observer kappa agreements were calculated. The capability of the synthesized contrasts and conventional TSE T2 to discern normal and pathologic cases was evaluated. Sixty patients were included. The overall diagnostic quality of the synthesized contrasts was non-inferior to conventional imaging scale (p=0.06). There was no significant difference in the legibility of normal and pathological anatomic structures of synthetized and conventional TSE T2 (all p > 0.05) as well as for artifacts except for phase encoding (p=0.008). Interobserver agreement was good to almost perfect (kappa between 0.66 and 1). T2 synthesized contrasts, which also provides quantitative T2 information that could be useful, could be suggested as an equivalent technique in pediatric neuro-imaging, compared to conventional TSE T2. Copyright © 2018. Published by Elsevier Masson SAS.

Biomechanical comparison of the double-push technique and the conventional skate skiing technique in cross-country sprint skiing.

PubMed

Stöggl, Thomas; Müller, Erich; Lindinger, Stefan

2008-09-01

The aims of the study were to: (1) adapt the "double-push" technique from inline skating to cross-country skiing; (2) compare this new skiing technique with the conventional skate skiing cross-country technique; and (3) test the hypothesis that the double-push technique improves skiing speed in a short sprint. 13 elite skiers performed maximum-speed sprints over 100 m using the double-push skate skiing technique and using the conventional "V2" skate skiing technique. Pole and plantar forces, knee angle, cycle characteristics, and electromyography of nine lower body muscles were analysed. We found that the double-push technique could be successfully transferred to cross-country skiing, and that this new technique is faster than the conventional skate skiing technique. The double-push technique was 2.9 +/- 2.2% faster (P < 0.001), which corresponds to a time advantage of 0.41 +/- 0.31 s over 100 m. The double-push technique had a longer cycle length and a lower cycle rate, and it was characterized by higher muscle activity, higher knee extension amplitudes and velocities, and higher peak foot forces, especially in the first phase of the push-off. Also, the foot was more loaded laterally in the double-push technique than in the conventional skate skiing technique.

Digital droplet multiple displacement amplification (ddMDA) for whole genome sequencing of limited DNA samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rhee, Minsoung; Light, Yooli K.; Meagher, Robert J.

Here, multiple displacement amplification (MDA) is a widely used technique for amplification of DNA from samples containing limited amounts of DNA (e.g., uncultivable microbes or clinical samples) before whole genome sequencing. Despite its advantages of high yield and fidelity, it suffers from high amplification bias and non-specific amplification when amplifying sub-nanogram of template DNA. Here, we present a microfluidic digital droplet MDA (ddMDA) technique where partitioning of the template DNA into thousands of sub-nanoliter droplets, each containing a small number of DNA fragments, greatly reduces the competition among DNA fragments for primers and polymerase thereby greatly reducing amplification bias. Consequently,more » the ddMDA approach enabled a more uniform coverage of amplification over the entire length of the genome, with significantly lower bias and non-specific amplification than conventional MDA. For a sample containing 0.1 pg/μL of E. coli DNA (equivalent of ~3/1000 of an E. coli genome per droplet), ddMDA achieves a 65-fold increase in coverage in de novo assembly, and more than 20-fold increase in specificity (percentage of reads mapping to E. coli) compared to the conventional tube MDA. ddMDA offers a powerful method useful for many applications including medical diagnostics, forensics, and environmental microbiology.« less

Digital droplet multiple displacement amplification (ddMDA) for whole genome sequencing of limited DNA samples

DOE PAGES

Rhee, Minsoung; Light, Yooli K.; Meagher, Robert J.; ...

2016-05-04

Here, multiple displacement amplification (MDA) is a widely used technique for amplification of DNA from samples containing limited amounts of DNA (e.g., uncultivable microbes or clinical samples) before whole genome sequencing. Despite its advantages of high yield and fidelity, it suffers from high amplification bias and non-specific amplification when amplifying sub-nanogram of template DNA. Here, we present a microfluidic digital droplet MDA (ddMDA) technique where partitioning of the template DNA into thousands of sub-nanoliter droplets, each containing a small number of DNA fragments, greatly reduces the competition among DNA fragments for primers and polymerase thereby greatly reducing amplification bias. Consequently,more » the ddMDA approach enabled a more uniform coverage of amplification over the entire length of the genome, with significantly lower bias and non-specific amplification than conventional MDA. For a sample containing 0.1 pg/μL of E. coli DNA (equivalent of ~3/1000 of an E. coli genome per droplet), ddMDA achieves a 65-fold increase in coverage in de novo assembly, and more than 20-fold increase in specificity (percentage of reads mapping to E. coli) compared to the conventional tube MDA. ddMDA offers a powerful method useful for many applications including medical diagnostics, forensics, and environmental microbiology.« less

[Utilization of Big Data in Medicine and Future Outlook].

PubMed

Kinosada, Yasutomi; Uematsu, Machiko; Fujiwara, Takuya

2016-03-01

"Big data" is a new buzzword. The point is not to be dazzled by the volume of data, but rather to analyze it, and convert it into insights, innovations, and business value. There are also real differences between conventional analytics and big data. In this article, we show some results of big data analysis using open DPC (Diagnosis Procedure Combination) data in areas of the central part of JAPAN: Toyama, Ishikawa, Fukui, Nagano, Gifu, Aichi, Shizuoka, and Mie Prefectures. These 8 prefectures contain 51 medical administration areas called the second medical area. By applying big data analysis techniques such as k-means, hierarchical clustering, and self-organizing maps to DPC data, we can visualize the disease structure and detect similarities or variations among the 51 second medical areas. The combination of a big data analysis technique and open DPC data is a very powerful method to depict real figures on patient distribution in Japan.

Railway deformation detected by DInSAR over active sinkholes in the Ebro Valley evaporite karst, Spain

NASA Astrophysics Data System (ADS)

Galve, J. P.; Castañeda, C.; Gutiérrez, F.

2015-11-01

Subsidence was measured for the first time on railway tracks in the central sector of Ebro Valley (NE Spain) using Differential Synthetic Aperture Radar Interferometry (DInSAR) techniques. This area is affected by evaporite karst and the analysed railway corridors traverse active sinkholes that produce deformations in these infrastructures. One of the railway tracks affected by slight settlements is the Madrid-Barcelona high-speed line, a form of transport infrastructure highly vulnerable to ground deformation processes. Our analysis based on DInSAR measurements and geomorphological surveys indicates that this line shows dissolution-induced subsidence and compaction of anthropogenic deposits (infills and embankments). Significant sinkhole-related subsidence was also measured by DInSAR techniques on the Castejón-Zaragoza conventional railway line. This study demonstrates that DInSAR velocity maps, coupled with detailed geomorphological surveys, may help in the identification of the railway track sections that are affected by active subsidence.

Comparison of soil pollution concentrations determined using AAS and portable XRF techniques.

PubMed

Radu, Tanja; Diamond, Dermot

2009-11-15

Past mining activities in the area of Silvermines, Ireland, have resulted in heavily polluted soils. The possibility of spreading pollution to the surrounding areas through dust blow-offs poses a potential threat for the local communities. Conventional environmental soil and dust analysis techniques are very slow and laborious and consequently there is a need for fast and accurate analytical methods, which can provide real-time in situ pollution mapping. Laboratory-based aqua regia acid digestion of the soil samples collected in the area followed by the atomic absorption spectrophotometry (AAS) analysis confirmed very high pollution, especially by Pb, As, Cu, and Zn. In parallel, samples were analyzed using portable X-ray fluorescence radioisotope and miniature tube powered (XRF) NITON instruments and their performance was compared. Overall, the portable XRF instrument gave excellent correlation with the laboratory-based reference AAS method.

Developing Gradient Metal Alloys through Radial Deposition Additive Manufacturing

PubMed Central

Hofmann, Douglas C.; Roberts, Scott; Otis, Richard; Kolodziejska, Joanna; Dillon, R. Peter; Suh, Jong-ook; Shapiro, Andrew A.; Liu, Zi-Kui; Borgonia, John-Paul

2014-01-01

Interest in additive manufacturing (AM) has dramatically expanded in the last several years, owing to the paradigm shift that the process provides over conventional manufacturing. Although the vast majority of recent work in AM has focused on three-dimensional printing in polymers, AM techniques for fabricating metal alloys have been available for more than a decade. Here, laser deposition (LD) is used to fabricate multifunctional metal alloys that have a strategically graded composition to alter their mechanical and physical properties. Using the technique in combination with rotational deposition enables fabrication of compositional gradients radially from the center of a sample. A roadmap for developing gradient alloys is presented that uses multi-component phase diagrams as maps for composition selection so as to avoid unwanted phases. Practical applications for the new technology are demonstrated in low-coefficient of thermal expansion radially graded metal inserts for carbon-fiber spacecraft panels. PMID:24942329

Submicron x-ray diffraction and its applications to problems in materials and environmental science

NASA Astrophysics Data System (ADS)

Tamura, N.; Celestre, R. S.; MacDowell, A. A.; Padmore, H. A.; Spolenak, R.; Valek, B. C.; Meier Chang, N.; Manceau, A.; Patel, J. R.

2002-03-01

The availability of high brilliance third generation synchrotron sources together with progress in achromatic focusing optics allows us to add submicron spatial resolution to the conventional century-old x-ray diffraction technique. The new capabilities include the possibility to map in situ, grain orientations, crystalline phase distribution, and full strain/stress tensors at a very local level, by combining white and monochromatic x-ray microbeam diffraction. This is particularly relevant for high technology industry where the understanding of material properties at a microstructural level becomes increasingly important. After describing the latest advances in the submicron x-ray diffraction techniques at the Advanced Light Source, we will give some examples of its application in material science for the measurement of strain/stress in metallic thin films and interconnects. Its use in the field of environmental science will also be discussed.

Topography and Mechanical Property Mapping of International Simple Glass Surfaces with Atomic Force Microscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pierce, Eric M

2014-01-01

Quantitative Nanomechanical Peak Force (PF-QNM) TappingModeTM atomic force microscopy measurements are presented for the first time on polished glass surfaces. The PF-QNM technique allows for topography and mechanical property information to be measured simultaneously at each pixel. Results for the international simple glass which represents a simplified version of SON68 glass suggests an average Young s modulus of 78.8 15.1 GPa is within the experimental error of the modulus measured for SON68 glass (83.6 2 GPa) with conventional approaches. Application of the PF-QNM technique will be extended to in situ glass corrosion experiments with the goal of gaining atomic-scale insightsmore » into altered layer development by exploiting the mechanical property differences that exist between silica gel (e.g., altered layer) and pristine glass surface.« less

Evaluation of a HDR image sensor with logarithmic response for mobile video-based applications

NASA Astrophysics Data System (ADS)

Tektonidis, Marco; Pietrzak, Mateusz; Monnin, David

2017-10-01

The performance of mobile video-based applications using conventional LDR (Low Dynamic Range) image sensors highly depends on the illumination conditions. As an alternative, HDR (High Dynamic Range) image sensors with logarithmic response are capable to acquire illumination-invariant HDR images in a single shot. We have implemented a complete image processing framework for a HDR sensor, including preprocessing methods (nonuniformity correction (NUC), cross-talk correction (CTC), and demosaicing) as well as tone mapping (TM). We have evaluated the HDR sensor for video-based applications w.r.t. the display of images and w.r.t. image analysis techniques. Regarding the display we have investigated the image intensity statistics over time, and regarding image analysis we assessed the number of feature correspondences between consecutive frames of temporal image sequences. For the evaluation we used HDR image data recorded from a vehicle on outdoor or combined outdoor/indoor itineraries, and we performed a comparison with corresponding conventional LDR image data.

Carrier-phase two-way satellite frequency transfer over a very long baseline

NASA Astrophysics Data System (ADS)

Fujieda, M.; Piester, D.; Gotoh, T.; Becker, J.; Aida, M.; Bauch, A.

2014-06-01

In this paper we report that carrier-phase two-way satellite time and frequency transfer (TWSTFT) was successfully demonstrated over a very long baseline of 9000 km, established between the National Institute of Information and Communications Technology (NICT) and the Physikalisch-Technische Bundesanstalt (PTB). We verified that the carrier-phase TWSTFT (TWCP) result agreed with those obtained by conventional TWSTFT and GPS carrier-phase (GPSCP) techniques. Moreover, a much improved short-term instability for frequency transfer of 2 × 10-13 at 1 s was achieved, which is at the same level as previously confirmed over a shorter baseline within Japan. The precision achieved was so high that the effects of ionospheric delay became significant; they are ignored in conventional TWSTFT even over a long link. We compensated for these effects using ionospheric delays computed from regional vertical total electron content maps. The agreement between the TWCP and GPSCP results was improved because of this compensation.

A Simplified Technique for Implant-Abutment Level Impression after Soft Tissue Adaptation around Provisional Restoration

PubMed Central

Kutkut, Ahmad; Abu-Hammad, Osama; Frazer, Robert

2016-01-01

Impression techniques for implant restorations can be implant level or abutment level impressions with open tray or closed tray techniques. Conventional implant-abutment level impression techniques are predictable for maximizing esthetic outcomes. Restoration of the implant traditionally requires the use of the metal or plastic impression copings, analogs, and laboratory components. Simplifying the dental implant restoration by reducing armamentarium through incorporating conventional techniques used daily for crowns and bridges will allow more general dentists to restore implants in their practices. The demonstrated technique is useful when modifications to implant abutments are required to correct the angulation of malpositioned implants. This technique utilizes conventional crown and bridge impression techniques. As an added benefit, it reduces costs by utilizing techniques used daily for crowns and bridges. The aim of this report is to describe a simplified conventional impression technique for custom abutments and modified prefabricated solid abutments for definitive restorations. PMID:29563457

Multipurpose, dual-mode imaging in the 3-5 μm range (MWIR) for artwork diagnostics: A systematic approach

NASA Astrophysics Data System (ADS)

Daffara, Claudia; Parisotto, Simone; Ambrosini, Dario

2018-05-01

We present a multi-purpose, dual-mode imaging method in the Mid-Wavelength Infrared (MWIR) range (from 3 μm to 5 μm) for a more efficient nondestructive analysis of artworks. Using a setup based on a MWIR thermal camera and multiple radiation sources, two radiometric image datasets are acquired in different acquisition modalities, the image in quasi-reflectance mode (TQR) and the thermal sequence in emission mode. Here, the advantages are: the complementarity of the information; the use of the quasi-reflectance map for calculating the emissivity map; the use of TQR map for a referentiation to the visible of the thermographic images. The concept of the method is presented, the practical feasibility is demonstrated through a custom imaging setup, the potentiality for the nondestructive analysis is shown on a notable application to cultural heritage. The method has been used as experimental tool in support of the restoration of the mural painting "Monocromo" by Leonardo da Vinci. Feedback from the operators and a comparison with some conventional diagnostic techniques is also given to underline the novelty and potentiality of the method.

Real-Space Mapping of Surface Trap States in CIGSe Nanocrystals Using 4D Electron Microscopy.

PubMed

Bose, Riya; Bera, Ashok; Parida, Manas R; Adhikari, Aniruddha; Shaheen, Basamat S; Alarousu, Erkki; Sun, Jingya; Wu, Tom; Bakr, Osman M; Mohammed, Omar F

2016-07-13

Surface trap states in copper indium gallium selenide semiconductor nanocrystals (NCs), which serve as undesirable channels for nonradiative carrier recombination, remain a great challenge impeding the development of solar and optoelectronics devices based on these NCs. In order to design efficient passivation techniques to minimize these trap states, a precise knowledge about the charge carrier dynamics on the NCs surface is essential. However, selective mapping of surface traps requires capabilities beyond the reach of conventional laser spectroscopy and static electron microscopy; it can only be accessed by using a one-of-a-kind, second-generation four-dimensional scanning ultrafast electron microscope (4D S-UEM) with subpicosecond temporal and nanometer spatial resolutions. Here, we precisely map the collective surface charge carrier dynamics of copper indium gallium selenide NCs as a function of the surface trap states before and after surface passivation in real space and time using S-UEM. The time-resolved snapshots clearly demonstrate that the density of the trap states is significantly reduced after zinc sulfide (ZnS) shelling. Furthermore, the removal of trap states and elongation of carrier lifetime are confirmed by the increased photocurrent of the self-biased photodetector fabricated using the shelled NCs.

Augmented Affordances Support Learning: Comparing the Instructional Effects of the Augmented Reality Sandbox and Conventional Maps to Teach Topographic Map Skills

ERIC Educational Resources Information Center

Richardson, R. Thomas; Sammons, Dotty; Del-Parte, Donna

2018-01-01

This study compared learning performance during and following AR and non-AR topographic map instruction and practice Two-way ANOVA testing indicated no significant differences on a posttest assessment between map type and spatial ability. Prior learning activity results revealed a significant performance difference between AR and non-AR treatment…

Multislice CT perfusion imaging of the lung in detection of pulmonary embolism

NASA Astrophysics Data System (ADS)

Hong, Helen; Lee, Jeongjin

2006-03-01

We propose a new subtraction technique for accurately imaging lung perfusion and efficiently detecting pulmonary embolism in chest MDCT angiography. Our method is composed of five stages. First, optimal segmentation technique is performed for extracting same volume of the lungs, major airway and vascular structures from pre- and post-contrast images with different lung density. Second, initial registration based on apex, hilar point and center of inertia (COI) of each unilateral lung is proposed to correct the gross translational mismatch. Third, initial alignment is refined by iterative surface registration. For fast and robust convergence of the distance measure to the optimal value, a 3D distance map is generated by the narrow-band distance propagation. Fourth, 3D nonlinear filter is applied to the lung parenchyma to compensate for residual spiral artifacts and artifacts caused by heart motion. Fifth, enhanced vessels are visualized by subtracting registered pre-contrast images from post-contrast images. To facilitate visualization of parenchyma enhancement, color-coded mapping and image fusion is used. Our method has been successfully applied to ten patients of pre- and post-contrast images in chest MDCT angiography. Experimental results show that the performance of our method is very promising compared with conventional methods with the aspects of its visual inspection, accuracy and processing time.

Advances in Spectral-Spatial Classification of Hyperspectral Images

NASA Technical Reports Server (NTRS)

Fauvel, Mathieu; Tarabalka, Yuliya; Benediktsson, Jon Atli; Chanussot, Jocelyn; Tilton, James C.

2012-01-01

Recent advances in spectral-spatial classification of hyperspectral images are presented in this paper. Several techniques are investigated for combining both spatial and spectral information. Spatial information is extracted at the object (set of pixels) level rather than at the conventional pixel level. Mathematical morphology is first used to derive the morphological profile of the image, which includes characteristics about the size, orientation, and contrast of the spatial structures present in the image. Then, the morphological neighborhood is defined and used to derive additional features for classification. Classification is performed with support vector machines (SVMs) using the available spectral information and the extracted spatial information. Spatial postprocessing is next investigated to build more homogeneous and spatially consistent thematic maps. To that end, three presegmentation techniques are applied to define regions that are used to regularize the preliminary pixel-wise thematic map. Finally, a multiple-classifier (MC) system is defined to produce relevant markers that are exploited to segment the hyperspectral image with the minimum spanning forest algorithm. Experimental results conducted on three real hyperspectral images with different spatial and spectral resolutions and corresponding to various contexts are presented. They highlight the importance of spectral–spatial strategies for the accurate classification of hyperspectral images and validate the proposed methods.

Spotlight SAR interferometry for terrain elevation mapping and interferometric change detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eichel, P.H.; Ghiglia, D.C.; Jakowatz, C.V. Jr.

1996-02-01

In this report, we employ an approach quite different from any previous work; we show that a new methodology leads to a simpler and clearer understanding of the fundamental principles of SAR interferometry. This methodology also allows implementation of an important collection mode that has not been demonstrated to date. Specifically, we introduce the following six new concepts for the processing of interferometric SAR (INSAR) data: (1) processing using spotlight mode SAR imaging (allowing ultra-high resolution), as opposed to conventional strip-mapping techniques; (2) derivation of the collection geometry constraints required to avoid decorrelation effects in two-pass INSAR; (3) derivation ofmore » maximum likelihood estimators for phase difference and the change parameter employed in interferometric change detection (ICD); (4) processing for the two-pass case wherein the platform ground tracks make a large crossing angle; (5) a robust least-squares method for two-dimensional phase unwrapping formulated as a solution to Poisson`s equation, instead of using traditional path-following techniques; and (6) the existence of a simple linear scale factor that relates phase differences between two SAR images to terrain height. We show both theoretical analysis, as well as numerous examples that employ real SAR collections to demonstrate the innovations listed above.« less

SIDS-toADF File Mapping Manual

NASA Technical Reports Server (NTRS)

McCarthy, Douglas; Smith, Matthew; Poirier, Diane; Smith, Charles A. (Technical Monitor)

2002-01-01

The "CFD General Notation System" (CGNS) consists of a collection of conventions, and conforming software, for the storage and retrieval of Computational Fluid Dynamics (CFD) data. It facilitates the exchange of data between sites and applications, and helps stabilize the archiving of aerodynamic data. This effort was initiated in order to streamline the procedures in exchanging data and software between NASA and its customers, but the goal is to develop CGNS into a National Standard for the exchange of aerodynamic data. The CGNS development team is comprised of members from Boeing Commercial Airplane Group, NASA-Ames, NASA-Langley, NASA-Lewis, McDonnell-Douglas Corporation (now Boeing-St. Louis), Air Force-Wright Lab., and ICEM-CFD Engineering. The elements of CGNS address all activities associated with the storage of data on external media and its movement to and from application programs. These elements include: 1) The Advanced Data Format (ADF) Database manager, consisting of both a file format specification and its I/O software, which handles the actual reading and writing of data from and to external storage media; 2) The Standard Interface Data Structures (SIDS), which specify the intellectual content of CFD data and the conventions governing naming and terminology; 3) The SIDS-to-ADF File Mapping conventions, which specify the exact location where the CFD data defined by the SIDS is to be stored within the ADF file(s); and 4) The CGNS Mid-level Library, which provides CFD-knowledgeable routines suitable for direct installation into application codes. The SIDS-toADF File Mapping Manual specifies the exact manner in which, under CGNS conventions, CFD data structures (the SIDS) are to be stored in (i.e., mapped onto) the file structure provided by the database manager (ADF). The result is a conforming CGNS database. Adherence to the mapping conventions guarantees uniform meaning and location of CFD data within ADF files, and thereby allows the construction of universal software to read and write the data.

Low-complexity peak-to-average power ratio reduction scheme for flip-orthogonal frequency division multiplexing visible light communication system based on μ-law mapping

NASA Astrophysics Data System (ADS)

Wang, Jianping; Zhang, Peiran; Lu, Huimin; Feng, LiFang

2017-06-01

An orthogonal frequency division multiplexing (OFDM) technique called flipped OFDM (flip-OFDM) is apposite for a visible light communication system that needs the transmitted signal to be real and positive. Flip-OFDM uses two consecutive OFDM subframes to transmit the positive and negative parts of the signal. However, peak-to-average power ratio (PAPR) for flip-OFDM is increased tremendously due to the low value of total average power that arises from many zero values in both the positive and flipped frames. We first analyze the performance of flip-OFDM and perform a comparison with the conventional DC-biased OFDM (DCO-OFDM); then we propose a flip-OFDM scheme combined with μ-law mapping to reduce the high PAPR. The simulation results show that the PAPR of the system is reduced about 17.2 and 5.9 dB when compared with the normal flip-OFDM and DCO-OFDM signals, respectively.

Artifact correction in diffusion MRI of non-human primate brains on a clinical 3T scanner.

PubMed

Zhang, Xiaodong; Kirsch, John E; Zhong, Xiaodong

2016-02-01

Smearing artifacts were observed and investigated in diffusion tensor imaging (DTI) studies of macaque monkeys on a clinical whole-body 3T scanner. Four adult macaques were utilized to evaluate DTI artifacts. DTI images were acquired with a single-shot echo-planar imaging (EPI) sequence using a parallel imaging technique. The smearing artifacts observed on the diffusion-weighted images and fractional anisotropy maps were caused by the incomplete fat suppression due to the irregular macaque frontal skull geometry and anatomy. The artifact can be reduced substantially using a novel three-dimensional (3D) shimming procedure. The smearing artifacts observed on diffusion weighted images and fractional anisotropy (FA) maps of macaque brains can be reduced substantially using a robust 3D shimming approach. The DTI protocol combined with the shimming procedure could be a robust approach to examine brain connectivity and white matter integrity of non-human primates using a conventional clinical setting. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Spatio-temporal mapping of variation potentials in leaves of Helianthus annuus L. seedlings in situ using multi-electrode array

PubMed Central

Zhao, Dong-Jie; Wang, Zhong-Yi; Huang, Lan; Jia, Yong-Peng; Leng, John Q.

2014-01-01

Damaging thermal stimuli trigger long-lasting variation potentials (VPs) in higher plants. Owing to limitations in conventional plant electrophysiological recording techniques, recorded signals are composed of signals originating from all of the cells that are connected to an electrode. This limitation does not enable detailed spatio-temporal distributions of transmission and electrical activities in plants to be visualised. Multi-electrode array (MEA) enables the recording and imaging of dynamic spatio-temporal electrical activities in higher plants. Here, we used an 8 × 8 MEA with a polar distance of 450 μm to measure electrical activities from numerous cells simultaneously. The mapping of the data that were recorded from the MEA revealed the transfer mode of the thermally induced VPs in the leaves of Helianthus annuus L. seedlings in situ. These results suggest that MEA can enable recordings with high spatio-temporal resolution that facilitate the determination of the bioelectrical response mode of higher plants under stress. PMID:24961469

Spatio-temporal mapping of variation potentials in leaves of Helianthus annuus L. seedlings in situ using multi-electrode array.

PubMed

Zhao, Dong-Jie; Wang, Zhong-Yi; Huang, Lan; Jia, Yong-Peng; Leng, John Q

2014-06-25

Damaging thermal stimuli trigger long-lasting variation potentials (VPs) in higher plants. Owing to limitations in conventional plant electrophysiological recording techniques, recorded signals are composed of signals originating from all of the cells that are connected to an electrode. This limitation does not enable detailed spatio-temporal distributions of transmission and electrical activities in plants to be visualised. Multi-electrode array (MEA) enables the recording and imaging of dynamic spatio-temporal electrical activities in higher plants. Here, we used an 8 × 8 MEA with a polar distance of 450 μm to measure electrical activities from numerous cells simultaneously. The mapping of the data that were recorded from the MEA revealed the transfer mode of the thermally induced VPs in the leaves of Helianthus annuus L. seedlings in situ. These results suggest that MEA can enable recordings with high spatio-temporal resolution that facilitate the determination of the bioelectrical response mode of higher plants under stress.

Analysis of advanced optical glass and systems

NASA Technical Reports Server (NTRS)

Johnson, R. Barry; Feng, Chen

1991-01-01

Optical lens systems performance utilizing optical materials comprising reluctant glass forming compositions was studied. Such special glasses are being explored by NASA/Marshall Space Flight Center (MSFC) researchers utilizing techniques such as containerless processing in space on the MSFC Acoustic Levitation Furnace and on the High Temperature Acoustic Levitation Furnace in the conceptual design phase for the United States Microgravity Laboratory (USML) series of shuttle flights. The application of high refractive index and low dispersive power glasses in optical lens design was investigated. The potential benefits and the impacts to the optical lens design performance were evaluated. The results of the studies revealed that the use of these extraordinary glasses can result in significant optical performance improvements. Recommendations of proposed optical properties for potential new glasses were also made. Applications of these new glasses are discussed, including the impact of high refractive index and low dispersive power, improvements of the system performance by using glasses which are located outside of traditional glass map, and considerations in establishing glass properties beyond conventional glass map limits.

X-Ray Fluorescence Imaging of Ancient Artifacts

NASA Astrophysics Data System (ADS)

Thorne, Robert; Geil, Ethan; Hudson, Kathryn; Crowther, Charles

2011-03-01

Many archaeological artifacts feature inscribed and/or painted text or figures which, through erosion and aging, have become difficult or impossible to read with conventional methods. Often, however, the pigments in paints contain metallic elements, and traces may remain even after visible markings are gone. A promising non-destructive technique for revealing these remnants is X-ray fluorescence (XRF) imaging, in which a tightly focused beam of monochromatic synchrotron radiation is raster scanned across a sample. At each pixel, an energy-dispersive detector records a fluorescence spectrum, which is then analyzed to determine element concentrations. In this way, a map of various elements is made across a region of interest. We have succesfully XRF imaged ancient Greek, Roman, and Mayan artifacts, and in many cases, the element maps have revealed significant new information, including previously invisible painted lines and traces of iron from tools used to carve stone tablets. X-ray imaging can be used to determine an object's provenance, including the region where it was produced and whether it is authentic or a copy.

Insights into photosystem II from isomorphous difference Fourier maps of femtosecond X-ray diffraction data and quantum mechanics/molecular mechanics structural models

DOE PAGES

Wang, Jimin; Askerka, Mikhail; Brudvig, Gary W.; ...

2017-01-12

Understanding structure–function relations in photosystem II (PSII) is important for the development of biomimetic photocatalytic systems. X-ray crystallography, computational modeling, and spectroscopy have played central roles in elucidating the structure and function of PSII. Recent breakthroughs in femtosecond X-ray crystallography offer the possibility of collecting diffraction data from the X-ray free electron laser (XFEL) before radiation damage of the sample, thereby overcoming the main challenge of conventional X-ray diffraction methods. However, the interpretation of XFEL data from PSII intermediates is challenging because of the issues regarding data-processing, uncertainty on the precise positions of light oxygen atoms next to heavy metalmore » centers, and different kinetics of the S-state transition in microcrystals compared to solution. Lastly, we summarize recent advances and outstanding challenges in PSII structure–function determination with emphasis on the implementation of quantum mechanics/molecular mechanics techniques combined with isomorphous difference Fourier maps, direct methods, and high-resolution spectroscopy.« less

Insights into Photosystem II from Isomorphous Difference Fourier Maps of Femtosecond X-ray Diffraction Data and Quantum Mechanics/Molecular Mechanics Structural Models.

PubMed

Wang, Jimin; Askerka, Mikhail; Brudvig, Gary W; Batista, Victor S

2017-02-10

Understanding structure-function relations in photosystem II (PSII) is important for the development of biomimetic photocatalytic systems. X-ray crystallography, computational modeling, and spectroscopy have played central roles in elucidating the structure and function of PSII. Recent breakthroughs in femtosecond X-ray crystallography offer the possibility of collecting diffraction data from the X-ray free electron laser (XFEL) before radiation damage of the sample, thereby overcoming the main challenge of conventional X-ray diffraction methods. However, the interpretation of XFEL data from PSII intermediates is challenging because of the issues regarding data-processing, uncertainty on the precise positions of light oxygen atoms next to heavy metal centers, and different kinetics of the S-state transition in microcrystals compared to solution. Here, we summarize recent advances and outstanding challenges in PSII structure-function determination with emphasis on the implementation of quantum mechanics/molecular mechanics techniques combined with isomorphous difference Fourier maps, direct methods, and high-resolution spectroscopy.

Railway deformation detected by DInSAR over active sinkholes in the Ebro Valley evaporite karst, Spain

NASA Astrophysics Data System (ADS)

Galve, J. P.; Castañeda, C.; Gutiérrez, F.

2015-06-01

Previously not measured subsidence on railway tracks was detected using DInSAR displacement maps produced for the central sector of Ebro Valley (NE Spain). This area is affected by evaporite karst and the analyzed railway corridors traverse active sinkholes that produce deformations in these infrastructures. One of the railway tracks affected by slight settlements corresponds to the Madrid-Barcelona high-speed line, a transport infrastructure highly vulnerable to ground deformation processes. Our analysis based on DInSAR measurements and geomorphological surveys indicate that this line show dissolution-induced subsidence and compaction of anthropogenic deposits (infills and embankments). By using DInSAR techniques, it was also measured the significant subsidence related to the activity of sinkholes in the Castejón-Zaragoza conventional railway line. Thus, this study demonstrate that DInSAR velocity maps coupled with detailed geomorphological surveys may help in the identification of the sectors of railway tracks that may compromise the safety of travellers.

Insights into photosystem II from isomorphous difference Fourier maps of femtosecond X-ray diffraction data and quantum mechanics/molecular mechanics structural models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Jimin; Askerka, Mikhail; Brudvig, Gary W.

Understanding structure–function relations in photosystem II (PSII) is important for the development of biomimetic photocatalytic systems. X-ray crystallography, computational modeling, and spectroscopy have played central roles in elucidating the structure and function of PSII. Recent breakthroughs in femtosecond X-ray crystallography offer the possibility of collecting diffraction data from the X-ray free electron laser (XFEL) before radiation damage of the sample, thereby overcoming the main challenge of conventional X-ray diffraction methods. However, the interpretation of XFEL data from PSII intermediates is challenging because of the issues regarding data-processing, uncertainty on the precise positions of light oxygen atoms next to heavy metalmore » centers, and different kinetics of the S-state transition in microcrystals compared to solution. Lastly, we summarize recent advances and outstanding challenges in PSII structure–function determination with emphasis on the implementation of quantum mechanics/molecular mechanics techniques combined with isomorphous difference Fourier maps, direct methods, and high-resolution spectroscopy.« less

Lithologic and structural mapping of the Abiete-Toko gold district in southern Cameroon, using Landsat 7 ETM+/SRTM

NASA Astrophysics Data System (ADS)

Binam Mandeng, Eugène Pascal; Bondjè Bidjeck, Louise Marie; Takodjou Wambo, Jonas Didero; Taku, Agbor; Bineli Betsi, Thierry; Solange Ipan, Antoinette; Tchami Nfada, Lionel; Bitom Dieudonné, Lucien

2018-03-01

The geology of the Abiete-Toko gold district in South Cameroon is investigated using a combination of Landsat 7 ETM+/SRTM image processing techniques, conventional geologic field mapping and geostatistical analysis. The satellite images were treated using Principal Component Analysis and Sobel filters to separate the background noise from lithotectonic structures which were matched with field data. The results show that this area has been affected by a polyphase deformation represented by S1 foliation, Sc1 schistosity, L1 lineation, S2 foliation, F2 folds, and F3 shear zones and faults. A detailed analysis of all the structures led to the identification of two major networks of dextral and sinistral shear zones oriented WNW-ESE and NE-SW, respectively. These results may serve in mining prospection, especially in the search for tectonically controlled primary mineralization and so may significantly guide the exploration of primary gold mineralization in the Abiete-Toko area subjected to years of artisanal gold mining.

Residual stress determination in oxide layers at different length scales combining Raman spectroscopy and X-ray diffraction: Application to chromia-forming metallic alloys

DOE PAGES

Guerain, Mathieu; Grosseau-Poussard, Jean-Luc; Geandier, Guillaume; ...

2017-11-21

In oxidizing environments, the protection of metals and alloys against further oxidation at high temperature is provided by the oxide film itself. This protection is efficient only if the formed film adheres well to the metal (substrate), i.e., without microcracks and spalls induced by thermomechanical stresses. In this study, the residual stresses at both macroscopic and microscopic scales in the oxide film adhering to the substrate and over the damaged areas have been rigorously determined on the same samples for both techniques. Ni-30Cr and Fe-47Cr alloys have been oxidized together at 900 and 1000 °C, respectively, to create films withmore » a thickness of a few microns. A multi-scale approach was adopted: macroscopic stress was determined by conventional X-ray diffraction and Raman spectroscopy, while microscopic residual stress mappings were performed over different types of bucklings using Raman micro-spectroscopy and synchrotron micro-diffraction. A very good agreement is found at macro- and microscales between the residual stress values obtained with both techniques, giving confidence on the reliability of the measurements. In addition, relevant structural information at the interface between the metallic substrate and the oxide layer was collected by micro-diffraction, a non-destructive technique that allows mapping through the oxide layer, and both the grain size and the crystallographic orientation of the supporting polycrystalline metal located either under a buckling or not were measured.« less

Residual stress determination in oxide layers at different length scales combining Raman spectroscopy and X-ray diffraction: Application to chromia-forming metallic alloys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guerain, Mathieu; Grosseau-Poussard, Jean-Luc; Geandier, Guillaume

In oxidizing environments, the protection of metals and alloys against further oxidation at high temperature is provided by the oxide film itself. This protection is efficient only if the formed film adheres well to the metal (substrate), i.e., without microcracks and spalls induced by thermomechanical stresses. In this study, the residual stresses at both macroscopic and microscopic scales in the oxide film adhering to the substrate and over the damaged areas have been rigorously determined on the same samples for both techniques. Ni-30Cr and Fe-47Cr alloys have been oxidized together at 900 and 1000 °C, respectively, to create films withmore » a thickness of a few microns. A multi-scale approach was adopted: macroscopic stress was determined by conventional X-ray diffraction and Raman spectroscopy, while microscopic residual stress mappings were performed over different types of bucklings using Raman micro-spectroscopy and synchrotron micro-diffraction. A very good agreement is found at macro- and microscales between the residual stress values obtained with both techniques, giving confidence on the reliability of the measurements. In addition, relevant structural information at the interface between the metallic substrate and the oxide layer was collected by micro-diffraction, a non-destructive technique that allows mapping through the oxide layer, and both the grain size and the crystallographic orientation of the supporting polycrystalline metal located either under a buckling or not were measured.« less

New constraints on deformation processes in serpentinite from sub-micron Raman Spectroscopy and TEM

NASA Astrophysics Data System (ADS)

Smith, S. A. F.; Tarling, M.; Rooney, J. S.; Gordon, K. C.; Viti, C.

2017-12-01

Extensive work has been performed to characterize the mineralogical and mechanical properties of the various serpentine minerals (i.e. antigorite, lizardite, chrysotile, polyhedral and polygonal serpentine). However, correct identification of serpentine minerals is often difficult or impossible using conventional analytical techniques such as optical- and SEM-based microscopy, X-ray diffraction and infrared spectroscopy. Transmission Electron Microscopy (TEM) is the best analytical technique to identify the serpentine minerals, but TEM requires complex sample preparation and typically results in very small analysis areas. Sub-micron confocal Raman spectroscopy mapping of polished thin sections provides a quick and relatively inexpensive way of unambiguously distinguishing the main serpentine minerals within their in-situ microstructural context. The combination of high spatial resolution (with a diffraction-limited system, 366 nm), large-area coverage (up to hundreds of microns in each dimension) and ability to map directly on thin sections allows intricate fault rock textures to be imaged at a sample-scale, which can then form the target of more focused TEM work. The potential of sub-micron Raman Spectroscopy + TEM is illustrated by examining sub-micron-scale mineral intergrowths and deformation textures in scaly serpentinites (e.g. dissolution seams, mineral growth in pressure shadows), serpentinite crack-seal veins and polished fault slip surfaces from a serpentinite-bearing mélange in New Zealand. The microstructural information provided by these techniques has yielded new insights into coseismic dehydration and amorphization processes and the interplay between creep and localised rupture in serpentinite shear zones.

Residual stress determination in oxide layers at different length scales combining Raman spectroscopy and X-ray diffraction: Application to chromia-forming metallic alloys

NASA Astrophysics Data System (ADS)

Guerain, Mathieu; Grosseau-Poussard, Jean-Luc; Geandier, Guillaume; Panicaud, Benoit; Tamura, Nobumichi; Kunz, Martin; Dejoie, Catherine; Micha, Jean-Sebastien; Thiaudière, Dominique; Goudeau, Philippe

2017-11-01

In oxidizing environments, the protection of metals and alloys against further oxidation at high temperature is provided by the oxide film itself. This protection is efficient only if the formed film adheres well to the metal (substrate), i.e., without microcracks and spalls induced by thermomechanical stresses. In this study, the residual stresses at both macroscopic and microscopic scales in the oxide film adhering to the substrate and over the damaged areas have been rigorously determined on the same samples for both techniques. Ni-30Cr and Fe-47Cr alloys have been oxidized together at 900 and 1000 °C, respectively, to create films with a thickness of a few microns. A multi-scale approach was adopted: macroscopic stress was determined by conventional X-ray diffraction and Raman spectroscopy, while microscopic residual stress mappings were performed over different types of bucklings using Raman micro-spectroscopy and synchrotron micro-diffraction. A very good agreement is found at macro- and microscales between the residual stress values obtained with both techniques, giving confidence on the reliability of the measurements. In addition, relevant structural information at the interface between the metallic substrate and the oxide layer was collected by micro-diffraction, a non-destructive technique that allows mapping through the oxide layer, and both the grain size and the crystallographic orientation of the supporting polycrystalline metal located either under a buckling or not were measured.

Evaluation of the Accuracy of Conventional and Digital Impression Techniques for Implant Restorations.

PubMed

Moura, Renata Vasconcellos; Kojima, Alberto Noriyuki; Saraceni, Cintia Helena Coury; Bassolli, Lucas; Balducci, Ivan; Özcan, Mutlu; Mesquita, Alfredo Mikail Melo

2018-05-01

The increased use of CAD systems can generate doubt about the accuracy of digital impressions for angulated implants. The aim of this study was to evaluate the accuracy of different impression techniques, two conventional and one digital, for implants with and without angulation. We used a polyurethane cast that simulates the human maxilla according to ASTM F1839, and 6 tapered implants were installed with external hexagonal connections to simulate tooth positions 17, 15, 12, 23, 25, and 27. Implants 17 and 23 were placed with 15° of mesial angulation and distal angulation, respectively. Mini cone abutments were installed on these implants with a metal strap 1 mm in height. Conventional and digital impression procedures were performed on the maxillary master cast, and the implants were separated into 6 groups based on the technique used and measurement type: G1 - control, G2 - digital impression, G3 - conventional impression with an open tray, G4 - conventional impression with a closed tray, G5 - conventional impression with an open tray and a digital impression, and G6 - conventional impression with a closed tray and a digital impression. A statistical analysis was performed using two-way repeated measures ANOVA to compare the groups, and a Kruskal-Wallis test was conducted to analyze the accuracy of the techniques. No significant difference in the accuracy of the techniques was observed between the groups. Therefore, no differences were found among the conventional impression and the combination of conventional and digital impressions, and the angulation of the implants did not affect the accuracy of the techniques. All of the techniques exhibited trueness and had acceptable precision. The variation of the angle of the implants did not affect the accuracy of the techniques. © 2018 by the American College of Prosthodontists.

Analyzing the Effects of Various Concept Mapping Techniques on Learning Achievement under Different Learning Styles

ERIC Educational Resources Information Center

Chiou, Chei-Chang; Lee, Li-Tze; Tien, Li-Chu; Wang, Yu-Min

2017-01-01

This study explored the effectiveness of different concept mapping techniques on the learning achievement of senior accounting students and whether achievements attained using various techniques are affected by different learning styles. The techniques are computer-assisted construct-by-self-concept mapping (CACSB), computer-assisted…

Computer-based self-organized tectonic zoning: a tentative pattern recognition for Iran

NASA Astrophysics Data System (ADS)

Zamani, Ahmad; Hashemi, Naser

2004-08-01

Conventional methods of tectonic zoning are frequently characterized by two deficiencies. The first one is the large uncertainty involved in tectonic zoning based on non-quantitative and subjective analysis. Failure to interpret accurately a large amount of data "by eye" is the second. In order to alleviate each of these deficiencies, the multivariate statistical method of cluster analysis has been utilized to seek and separate zones with similar tectonic pattern and construct automated self-organized multivariate tectonic zoning maps. This analytical method of tectonic regionalization is particularly useful for showing trends in tectonic evolution of a region that could not be discovered by any other means. To illustrate, this method has been applied for producing a general-purpose numerical tectonic zoning map of Iran. While there are some similarities between the self-organized multivariate numerical maps and the conventional maps, the cluster solution maps reveal some remarkable features that cannot be observed on the current tectonic maps. The following specific examples need to be noted: (1) The much disputed extent and rigidity of the Lut Rigid Block, described as the microplate of east Iran, is clearly revealed on the self-organized numerical maps. (2) The cluster solution maps reveal a striking similarity between this microplate and the northern Central Iran—including the Great Kavir region. (3) Contrary to the conventional map, the cluster solution maps make a clear distinction between the East Iranian Ranges and the Makran Mountains. (4) Moreover, an interesting similarity between the Azarbaijan region in the northwest and the Makran Mountains in the southeast and between the Kopet Dagh Ranges in the northeast and the Zagros Folded Belt in the southwest of Iran are revealed in the clustering process. This new approach to tectonic zoning is a starting point and is expected to be improved and refined by collection of new data. The method is also a useful tool in studying neotectonics, seismotectonics, seismic zoning, and hazard estimation of the seismogenic regions.

1994 ASPRS/ACSM annual convention exposition. Volume 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-01-01

This report is Volume II of presented papers at the joint 1994 convention of the American Society for Photgrammetry and Remote Sensing and American Congress on Surveying and Mapping. Topic areas covered include the following: Data Base/GPS Issues; Survey Management Issues; Surveying computations; Surveying education; Digital mapping; global change, EOS and NALC issues; GPS issues; Battelle Research in Remote Sensing and in GIS; Advanced Image Processing;GIS Issues; Surveying and Geodesy Issues; water resource issues; Advanced applications of remote sensing; Landsat Pathfinder I.

SiSeRHMap v1.0: a simulator for mapped seismic response using a hybrid model

NASA Astrophysics Data System (ADS)

Grelle, G.; Bonito, L.; Lampasi, A.; Revellino, P.; Guerriero, L.; Sappa, G.; Guadagno, F. M.

2015-06-01

SiSeRHMap is a computerized methodology capable of drawing up prediction maps of seismic response. It was realized on the basis of a hybrid model which combines different approaches and models in a new and non-conventional way. These approaches and models are organized in a code-architecture composed of five interdependent modules. A GIS (Geographic Information System) Cubic Model (GCM), which is a layered computational structure based on the concept of lithodynamic units and zones, aims at reproducing a parameterized layered subsoil model. A metamodeling process confers a hybrid nature to the methodology. In this process, the one-dimensional linear equivalent analysis produces acceleration response spectra of shear wave velocity-thickness profiles, defined as trainers, which are randomly selected in each zone. Subsequently, a numerical adaptive simulation model (Spectra) is optimized on the above trainer acceleration response spectra by means of a dedicated Evolutionary Algorithm (EA) and the Levenberg-Marquardt Algorithm (LMA) as the final optimizer. In the final step, the GCM Maps Executor module produces a serial map-set of a stratigraphic seismic response at different periods, grid-solving the calibrated Spectra model. In addition, the spectra topographic amplification is also computed by means of a numerical prediction model. This latter is built to match the results of the numerical simulations related to isolate reliefs using GIS topographic attributes. In this way, different sets of seismic response maps are developed, on which, also maps of seismic design response spectra are defined by means of an enveloping technique.

A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes.

PubMed

Davidson, Edgar; Doranz, Benjamin J

2014-09-01

Characterizing the binding sites of monoclonal antibodies (mAbs) on protein targets, their 'epitopes', can aid in the discovery and development of new therapeutics, diagnostics and vaccines. However, the speed of epitope mapping techniques has not kept pace with the increasingly large numbers of mAbs being isolated. Obtaining detailed epitope maps for functionally relevant antibodies can be challenging, particularly for conformational epitopes on structurally complex proteins. To enable rapid epitope mapping, we developed a high-throughput strategy, shotgun mutagenesis, that enables the identification of both linear and conformational epitopes in a fraction of the time required by conventional approaches. Shotgun mutagenesis epitope mapping is based on large-scale mutagenesis and rapid cellular testing of natively folded proteins. Hundreds of mutant plasmids are individually cloned, arrayed in 384-well microplates, expressed within human cells, and tested for mAb reactivity. Residues are identified as a component of a mAb epitope if their mutation (e.g. to alanine) does not support candidate mAb binding but does support that of other conformational mAbs or allows full protein function. Shotgun mutagenesis is particularly suited for studying structurally complex proteins because targets are expressed in their native form directly within human cells. Shotgun mutagenesis has been used to delineate hundreds of epitopes on a variety of proteins, including G protein-coupled receptor and viral envelope proteins. The epitopes mapped on dengue virus prM/E represent one of the largest collections of epitope information for any viral protein, and results are being used to design better vaccines and drugs. © 2014 John Wiley & Sons Ltd.

Productive Figurative Communication: Conventional Metaphors Facilitate the Comprehension of Related Novel Metaphors

ERIC Educational Resources Information Center

Thibodeau, Paul; Durgin, Frank H.

2008-01-01

Three experiments explored whether conceptual mappings in conventional metaphors are productive, by testing whether the comprehension of novel metaphors was facilitated by first reading conceptually related conventional metaphors. The first experiment, a replication and extension of Keysar et al. [Keysar, B., Shen, Y., Glucksberg, S., Horton, W.…

Mapping Henry: Synchrotron-sourced X-ray fluorescence mapping and ultra-high-definition scanning of an early Tudor portrait of Henry VIII

NASA Astrophysics Data System (ADS)

Dredge, Paula; Ives, Simon; Howard, Daryl L.; Spiers, Kathryn M.; Yip, Andrew; Kenderdine, Sarah

2015-11-01

A portrait of Henry VIII on oak panel c. 1535 has recently undergone technical examination to inform questions regarding authorship and the painting's relationship to a group of similar works in the collections of the National Portrait Gallery, London, and the Society of Antiquaries. Due to previous conservation treatments of the painting, the conventional transmission X-radiograph image was difficult to interpret. As a result, the painting underwent high-definition X-ray fluorescence (XRF) elemental mapping on the X-ray fluorescence microscopy beamline of the Australian Synchrotron. Scans were conducted at 12.6 and 18.5 keV, below and above the lead (Pb) L edges, respectively. Typical scan parameters were 120 μm pixel size at 7 ms dwell time, with the largest scan covering an area 545 × 287 mm2 collected in 23 h (10.8 MP). XRF mapping of the panel has guided the conservation treatment of the painting and the revelation of previously obscured features. It has also provided insight into the process of making of the painting. The informative and detailed elemental maps, alongside ultra-high-definition scans of the painting undertaken before and after varnish and over-paint removal, have assisted in comparison of the finely painted details with the London paintings. The resolution offered by the combination of imaging techniques identifies pigment distribution at an extremely fine scale, enabling a new understanding of the artist's paint application.

SiSeRHMap v1.0: a simulator for mapped seismic response using a hybrid model

NASA Astrophysics Data System (ADS)

Grelle, Gerardo; Bonito, Laura; Lampasi, Alessandro; Revellino, Paola; Guerriero, Luigi; Sappa, Giuseppe; Guadagno, Francesco Maria

2016-04-01

The SiSeRHMap (simulator for mapped seismic response using a hybrid model) is a computerized methodology capable of elaborating prediction maps of seismic response in terms of acceleration spectra. It was realized on the basis of a hybrid model which combines different approaches and models in a new and non-conventional way. These approaches and models are organized in a code architecture composed of five interdependent modules. A GIS (geographic information system) cubic model (GCM), which is a layered computational structure based on the concept of lithodynamic units and zones, aims at reproducing a parameterized layered subsoil model. A meta-modelling process confers a hybrid nature to the methodology. In this process, the one-dimensional (1-D) linear equivalent analysis produces acceleration response spectra for a specified number of site profiles using one or more input motions. The shear wave velocity-thickness profiles, defined as trainers, are randomly selected in each zone. Subsequently, a numerical adaptive simulation model (Emul-spectra) is optimized on the above trainer acceleration response spectra by means of a dedicated evolutionary algorithm (EA) and the Levenberg-Marquardt algorithm (LMA) as the final optimizer. In the final step, the GCM maps executor module produces a serial map set of a stratigraphic seismic response at different periods, grid solving the calibrated Emul-spectra model. In addition, the spectra topographic amplification is also computed by means of a 3-D validated numerical prediction model. This model is built to match the results of the numerical simulations related to isolate reliefs using GIS morphometric data. In this way, different sets of seismic response maps are developed on which maps of design acceleration response spectra are also defined by means of an enveloping technique.

Efficient, Validated Method for Detection of Mycobacterial Growth in Liquid Culture Media by Use of Bead Beating, Magnetic-Particle-Based Nucleic Acid Isolation, and Quantitative PCR

PubMed Central

Waldron, Anna M.; Begg, Douglas J.; de Silva, Kumudika; Purdie, Auriol C.; Whittington, Richard J.

2015-01-01

Pathogenic mycobacteria are difficult to culture, requiring specialized media and a long incubation time, and have complex and exceedingly robust cell walls. Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne's disease, a chronic wasting disease of ruminants, is a typical example. Culture of MAP from the feces and intestinal tissues is a commonly used test for confirmation of infection. Liquid medium offers greater sensitivity than solid medium for detection of MAP; however, support for the BD Bactec 460 system commonly used for this purpose has been discontinued. We previously developed a new liquid culture medium, M7H9C, to replace it, with confirmation of growth reliant on PCR. Here, we report an efficient DNA isolation and quantitative PCR methodology for the specific detection and confirmation of MAP growth in liquid culture media containing egg yolk. The analytical sensitivity was at least 104-fold higher than a commonly used method involving ethanol precipitation of DNA and conventional PCR; this may be partly due to the addition of a bead-beating step to manually disrupt the cell wall of the mycobacteria. The limit of detection, determined using pure cultures of two different MAP strains, was 100 to 1,000 MAP organisms/ml. The diagnostic accuracy was confirmed using a panel of cattle fecal (n = 54) and sheep fecal and tissue (n = 90) culture samples. This technique is directly relevant for diagnostic laboratories that perform MAP cultures but may also be applicable to the detection of other species, including M. avium and M. tuberculosis. PMID:25609725

The frequency-domain approach for apparent density mapping

NASA Astrophysics Data System (ADS)

Tong, T.; Guo, L.

2017-12-01

Apparent density mapping is a technique to estimate density distribution in the subsurface layer from the observed gravity data. It has been widely applied for geologic mapping, tectonic study and mineral exploration for decades. Apparent density mapping usually models the density layer as a collection of vertical, juxtaposed prisms in both horizontal directions, whose top and bottom surfaces are assumed to be horizontal or variable-depth, and then inverts or deconvolves the gravity anomalies to determine the density of each prism. Conventionally, the frequency-domain approach, which assumes that both top and bottom surfaces of the layer are horizontal, is usually utilized for fast density mapping. However, such assumption is not always valid in the real world, since either the top surface or the bottom surface may be variable-depth. Here, we presented a frequency-domain approach for apparent density mapping, which permits both the top and bottom surfaces of the layer to be variable-depth. We first derived the formula for forward calculation of gravity anomalies caused by the density layer, whose top and bottom surfaces are variable-depth, and the formula for inversion of gravity anomalies for the density distribution. Then we proposed the procedure for density mapping based on both the formulas of inversion and forward calculation. We tested the approach on the synthetic data, which verified its effectiveness. We also tested the approach on the real Bouguer gravity anomalies data from the central South China. The top surface was assumed to be flat and was on the sea level, and the bottom surface was considered as the Moho surface. The result presented the crustal density distribution, which was coinciding well with the basic tectonic features in the study area.

Efficient, validated method for detection of mycobacterial growth in liquid culture media by use of bead beating, magnetic-particle-based nucleic acid isolation, and quantitative PCR.

PubMed

Plain, Karren M; Waldron, Anna M; Begg, Douglas J; de Silva, Kumudika; Purdie, Auriol C; Whittington, Richard J

2015-04-01

Pathogenic mycobacteria are difficult to culture, requiring specialized media and a long incubation time, and have complex and exceedingly robust cell walls. Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne's disease, a chronic wasting disease of ruminants, is a typical example. Culture of MAP from the feces and intestinal tissues is a commonly used test for confirmation of infection. Liquid medium offers greater sensitivity than solid medium for detection of MAP; however, support for the BD Bactec 460 system commonly used for this purpose has been discontinued. We previously developed a new liquid culture medium, M7H9C, to replace it, with confirmation of growth reliant on PCR. Here, we report an efficient DNA isolation and quantitative PCR methodology for the specific detection and confirmation of MAP growth in liquid culture media containing egg yolk. The analytical sensitivity was at least 10(4)-fold higher than a commonly used method involving ethanol precipitation of DNA and conventional PCR; this may be partly due to the addition of a bead-beating step to manually disrupt the cell wall of the mycobacteria. The limit of detection, determined using pure cultures of two different MAP strains, was 100 to 1,000 MAP organisms/ml. The diagnostic accuracy was confirmed using a panel of cattle fecal (n=54) and sheep fecal and tissue (n=90) culture samples. This technique is directly relevant for diagnostic laboratories that perform MAP cultures but may also be applicable to the detection of other species, including M. avium and M. tuberculosis. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Investigation of stratigraphic mapping in paintings using micro-Raman spectroscopy

NASA Astrophysics Data System (ADS)

Karagiannis, Georgios Th.; Apostolidis, Georgios K.

2016-04-01

In this work, microRaman spectroscopy is used to investigate the stratigraphic mapping in paintings. The objective of mapping imaging is to segment the dataset, here spectra, into clusters each of which consisting spectra that have similar characteristics; hence, similar chemical composition. The spatial distribution of such clusters can be illustrated in pseudocolor images, in which each pixel of image is colored according to its cluster membership. Such mapping images convey information about the spatial distribution of the chemical substances in an object. Moreover, the laser light source that is used has excitation in 1064 nm, i.e., near infrared (NIR), allowing the penetration of the radiation in deeper layers. Thus, the mapping images that are produced by clustering the acquired spectra (specifying specific bands of Raman shifts) can provide stratigraphic information in the mapping images, i.e., images that convey information of the distribution of substances from deeper, as well. To cluster the spectra, unsupervised machine learning algorithms are applied, e.g., hierarchical clustering. Furthermore, the optical microscopy camera (×50), where the Raman probe (B and WTek iRaman EX) is plugged in, is attached to a computerized numerical control (CNC) system which is driven by a software that is specially developed for Raman mapping. This software except for the conventional CNC operation allows the user to parameterize the spectrometer and check each and every measurement to ensure proper acquisition. This facility is important in painting investigation because some materials are vulnerable to such specific parameterization that other materials demand. The technique is tested on a portable experimental overpainted icon of a known stratigraphy. Specifically, the under icon, i.e., the wavy hair of "Saint James", can be separated from upper icon, i.e., the halo of Mother of God in the "Descent of the Cross".

A Comparative Evaluation of the Effect of Double Casting Technique Using Functionally Generated Path and Conventional Single Casting with Respect to Functional Articulation, Patient Satisfaction and Chair Side Time, in Single Unit Molar Teeth: An In Vivo Study.

PubMed

Memon, Sarfaraz

2014-12-01

A stable centric occlusal position that shows no evidence of occlusal disease should not be altered. Confirmative restorative dentistry deals with making restorations that are in harmony with existing jaw relations. Conventional techniques for construction have been unsuccessful in producing a prosthesis that can be inserted without minor intraoral occlusal adjustment. This study was conducted to evaluate the benefits of the double casting technique with FGP over the conventional casting technique. Ten patients with root canal treated maxillary molar were selected for the fabrication of metal crown. Two techniques, one involving the conventional fabrication and other using functionally generated path with double casting were used to fabricate the prosthesis. A comparison based on various parameters which was done between the two techniques. The change in the height of castings for the double casting group was less compared to the conventional group and was highly statistically significant (P < 0.001). The time taken for occlusal correction was significantly lower in double casting group than the conventional group (P < 0.001). The patient satisfaction (before occlusal correction) indicated better satisfaction for double casting group compared to conventional (P < 0.01). The functionally generated path with double casting technique resulted in castings which had better dimensional accuracy, less occlusal correction and better patient satisfaction compared to the conventional castings.

The Safety Course Design and Operations of Composite Overwrapped Pressure Vessels (COPV)

NASA Technical Reports Server (NTRS)

Saulsberry, Regor; Prosser, William

2015-01-01

Following a Commercial Launch Vehicle On-Pad COPV (Composite Overwrapped Pressure Vessels) failure, a request was received by the NESC (NASA Engineering and Safety Center) June 14, 2014. An assessment was approved July 10, 2014, to develop and assess the capability of scanning eddy current (EC) nondestructive evaluation (NDE) methods for mapping thickness and inspection for flaws. Current methods could not identify thickness reduction from necking and critical flaw detection was not possible with conventional dye penetrant (PT) methods, so sensitive EC scanning techniques were needed. Developmental methods existed, but had not been fully developed, nor had the requisite capability assessment (i.e., a POD (Probability of Detection) study) been performed.

Comparison of digital and conventional impression techniques: evaluation of patients' perception, treatment comfort, effectiveness and clinical outcomes.

PubMed

Yuzbasioglu, Emir; Kurt, Hanefi; Turunc, Rana; Bilir, Halenur

2014-01-30

The purpose of this study was to compare two impression techniques from the perspective of patient preferences and treatment comfort. Twenty-four (12 male, 12 female) subjects who had no previous experience with either conventional or digital impression participated in this study. Conventional impressions of maxillary and mandibular dental arches were taken with a polyether impression material (Impregum, 3 M ESPE), and bite registrations were made with polysiloxane bite registration material (Futar D, Kettenbach). Two weeks later, digital impressions and bite scans were performed using an intra-oral scanner (CEREC Omnicam, Sirona). Immediately after the impressions were made, the subjects' attitudes, preferences and perceptions towards impression techniques were evaluated using a standardized questionnaire. The perceived source of stress was evaluated using the State-Trait Anxiety Scale. Processing steps of the impression techniques (tray selection, working time etc.) were recorded in seconds. Statistical analyses were performed with the Wilcoxon Rank test, and p < 0.05 was considered significant. There were significant differences among the groups (p < 0.05) in terms of total working time and processing steps. Patients stated that digital impressions were more comfortable than conventional techniques. Digital impressions resulted in a more time-efficient technique than conventional impressions. Patients preferred the digital impression technique rather than conventional techniques.

Quantitative T2 mapping of recurrent glioblastoma under bevacizumab improves monitoring for non-enhancing tumor progression and predicts overall survival

PubMed Central

Hattingen, Elke; Jurcoane, Alina; Daneshvar, Keivan; Pilatus, Ulrich; Mittelbronn, Michel; Steinbach, Joachim P.; Bähr, Oliver

2013-01-01

Background Anti-angiogenic treatment in recurrent glioblastoma patients suppresses contrast enhancement and reduces vasogenic edema while non-enhancing tumor progression is common. Thus, the importance of T2-weighted imaging is increasing. We therefore quantified T2 relaxation times, which are the basis for the image contrast on T2-weighted images. Methods Conventional and quantitative MRI procedures were performed on 18 patients with recurrent glioblastoma before treatment with bevacizumab and every 8 weeks thereafter until further tumor progression. We segmented the tumor on conventional MRI into 3 subvolumes: enhancing tumor, non-enhancing tumor, and edema. Using coregistered quantitative maps, we followed changes in T2 relaxation time in each subvolume. Moreover, we generated differential T2 maps by a voxelwise subtraction using the first T2 map under bevacizumab as reference. Results Visually segmented areas of tumor and edema did not differ in T2 relaxation times. Non-enhancing tumor volume did not decrease after commencement of bevacizumab treatment but strikingly increased at progression. Differential T2 maps clearly showed non-enhancing tumor progression in previously normal brain. T2 relaxation times decreased under bevacizumab without re-increasing at tumor progression. A decrease of <26 ms in the enhancing tumor following exposure to bevacizumab was associated with longer overall survival. Conclusions Combining quantitative MRI and tumor segmentation improves monitoring of glioblastoma patients under bevacizumab. The degree of change in T2 relaxation time under bevacizumab may be an early response parameter predictive of overall survival. The sustained decrease in T2 relaxation times toward values of healthy tissue masks progressive tumor on conventional T2-weighted images. Therefore, quantitative T2 relaxation times may detect non-enhancing progression better than conventional T2-weighted imaging. PMID:23925453

Testing Beyond Words: Using Tests to Enhance Visuospatial Map Learning

ERIC Educational Resources Information Center

Carpenter, Shana K.; Pashler, Harold

2007-01-01

Psychological research shows that learning can be powerfully enhanced through testing, but this finding has so far been confined to memory tasks requiring verbal responses. We explored whether testing can enhance learning of visuospatial information in maps. Fifty subjects each studied 2 maps, one through conventional study, and the other through…

Teaching Topographic Map Skills and Geomorphology Concepts with Google Earth in a One-Computer Classroom

ERIC Educational Resources Information Center

Hsu, Hsiao-Ping; Tsai, Bor-Wen; Chen, Che-Ming

2018-01-01

Teaching high-school geomorphological concepts and topographic map reading entails many challenges. This research reports the applicability and effectiveness of Google Earth in teaching topographic map skills and geomorphological concepts, by a single teacher, in a one-computer classroom. Compared to learning via a conventional instructional…

Evaluation of the marginal fit of metal copings fabricated on three different marginal designs using conventional and accelerated casting techniques: an in vitro study.

PubMed

Vaidya, Sharad; Parkash, Hari; Bhargava, Akshay; Gupta, Sharad

2014-01-01

Abundant resources and techniques have been used for complete coverage crown fabrication. Conventional investing and casting procedures for phosphate-bonded investments require a 2- to 4-h procedure before completion. Accelerated casting techniques have been used, but may not result in castings with matching marginal accuracy. The study measured the marginal gap and determined the clinical acceptability of single cast copings invested in a phosphate-bonded investment with the use of conventional and accelerated methods. One hundred and twenty cast coping samples were fabricated using conventional and accelerated methods, with three finish lines: Chamfer, shoulder and shoulder with bevel. Sixty copings were prepared with each technique. Each coping was examined with a stereomicroscope at four predetermined sites and measurements of marginal gaps were documented for each. A master chart was prepared for all the data and was analyzed using Statistical Package for the Social Sciences version. Evidence of marginal gap was then evaluated by t-test. Analysis of variance and Post-hoc analysis were used to compare two groups as well as to make comparisons between three subgroups . Measurements recorded showed no statistically significant difference between conventional and accelerated groups. Among the three marginal designs studied, shoulder with bevel showed the best marginal fit with conventional as well as accelerated casting techniques. Accelerated casting technique could be a vital alternative to the time-consuming conventional casting technique. The marginal fit between the two casting techniques showed no statistical difference.

The Effectiveness of Panoramic Maps Design: a Preliminary Study Based on Mobile Eye-Tracking

NASA Astrophysics Data System (ADS)

Balzarini, R.; Murat, M.

2016-06-01

This paper presents preliminary results from an ongoing research based on the study of visual attention through mobile eye-tracking techniques. The visual-cognitive approach investigates the reading-comprehension of a particular territorial representation: ski trails maps. The general issue of the study is to provide insights about the effectiveness of panoramic ski maps and more broadly, to suggest innovative efficient representation of the geographic information in mountain. According to some mountain operators, the information provided by paper ski maps no longer meets the needs of a large part of the customers; the question now arises of their adaptation to new digital practices (iPhone, tablets). In a computerized process perspective, this study particularly focuses on the representations, and the inferred information, which are really helpful to the users-skiers to apprehend the territory and make decisions, and which could be effectively replicated into a digital system. The most interesting output relies on the relevance of the panorama view: panorama still fascinates, but contrary to conventional wisdom, the information it provides does not seem to be useful to the skier. From a socio-historical perspective this study shows how empirical evidence-based approach can support the change: our results enhance the discussion on the effectiveness of the message that mountain operators want to convey to the tourist and therefore, on the renewal of (geographical) information in ski resorts.

Applying multibeam sonar and mathematical modeling for mapping seabed substrate and biota of offshore shallows

NASA Astrophysics Data System (ADS)

Herkül, Kristjan; Peterson, Anneliis; Paekivi, Sander

2017-06-01

Both basic science and marine spatial planning are in a need of high resolution spatially continuous data on seabed habitats and biota. As conventional point-wise sampling is unable to cover large spatial extents in high detail, it must be supplemented with remote sensing and modeling in order to fulfill the scientific and management needs. The combined use of in situ sampling, sonar scanning, and mathematical modeling is becoming the main method for mapping both abiotic and biotic seabed features. Further development and testing of the methods in varying locations and environmental settings is essential for moving towards unified and generally accepted methodology. To fill the relevant research gap in the Baltic Sea, we used multibeam sonar and mathematical modeling methods - generalized additive models (GAM) and random forest (RF) - together with underwater video to map seabed substrate and epibenthos of offshore shallows. In addition to testing the general applicability of the proposed complex of techniques, the predictive power of different sonar-based variables and modeling algorithms were tested. Mean depth, followed by mean backscatter, were the most influential variables in most of the models. Generally, mean values of sonar-based variables had higher predictive power than their standard deviations. The predictive accuracy of RF was higher than that of GAM. To conclude, we found the method to be feasible and with predictive accuracy similar to previous studies of sonar-based mapping.

Singleshot T1 Mapping using Simultaneous Acquisitions of Spin- and STimulated-Echo Planar Imaging (2D ss-SESTEPI)

PubMed Central

Shi, Xianfeng; Kim, Seong-Eun; Jeong, Eun-Kee

2011-01-01

The conventional stimulated-echo NMR sequence only measures the longitudinal component, while discarding the transverse component, after tipping up the prepared magnetization. This transverse magnetization can be used to measure a spin-echo, in addition to the stimulated-echo. 2D ss-SESTEPI is an EPI-based singleshot imaging technique that simultaneously acquires a spin-echo-planar image (SEPI) and a stimulated-echo-planar image (STEPI) after a single RF excitation. The magnitudes of SEPI and STEPI differ by T1 decay and diffusion weighting for perfect 90° RF, and thus can be used to rapidly measure T1. However, the spatial variation of B1 amplitude induces un-even splitting of the transverse magnetization for SEPI and STEPI within the imaging FOV. Correction for B1 inhomogeneity is therefore critical for 2D ss-SESTEPI to be used for T1 measurement. We developed a method for B1 inhomogeneity correction by acquiring an additional STEPI with minimal mixing time, calculating the difference between the spin-echo and the stimulated-echo and multiplying the STEPI by the inverse functional map. Diffusion-induced decay is corrected by measuring the average diffusivity during the prescanning. Rapid singleshot T1 mapping may be useful for various applications, such as dynamic T1 mapping for real-time estimation of the concentration of contrast agent in DCE-MRI. PMID:20564579

Combining Techniques to Refine Item to Skills Q-Matrices with a Partition Tree

ERIC Educational Resources Information Center

Desmarais, Michel C.; Xu, Peng; Beheshti, Behzad

2015-01-01

The problem of mapping items to skills is gaining interest with the emergence of recent techniques that can use data for both defining this mapping, and for refining mappings given by experts. We investigate the problem of refining mapping from an expert by combining the output of different techniques. The combination is based on a partition tree…

Comparative Evaluation of Conventional and Accelerated Castings on Marginal Fit and Surface Roughness.

PubMed

Jadhav, Vivek Dattatray; Motwani, Bhagwan K; Shinde, Jitendra; Adhapure, Prasad

2017-01-01

The aim of this study was to evaluate the marginal fit and surface roughness of complete cast crowns made by a conventional and an accelerated casting technique. This study was divided into three parts. In Part I, the marginal fit of full metal crowns made by both casting techniques in the vertical direction was checked, in Part II, the fit of sectional metal crowns in the horizontal direction made by both casting techniques was checked, and in Part III, the surface roughness of disc-shaped metal plate specimens made by both casting techniques was checked. A conventional technique was compared with an accelerated technique. In Part I of the study, the marginal fit of the full metal crowns as well as in Part II, the horizontal fit of sectional metal crowns made by both casting techniques was determined, and in Part III, the surface roughness of castings made with the same techniques was compared. The results of the t -test and independent sample test do not indicate statistically significant differences in the marginal discrepancy detected between the two casting techniques. For the marginal discrepancy and surface roughness, crowns fabricated with the accelerated technique were significantly different from those fabricated with the conventional technique. Accelerated casting technique showed quite satisfactory results, but the conventional technique was superior in terms of marginal fit and surface roughness.

Dynamical density delay maps: simple, new method for visualising the behaviour of complex systems

PubMed Central

2014-01-01

Background Physiologic signals, such as cardiac interbeat intervals, exhibit complex fluctuations. However, capturing important dynamical properties, including nonstationarities may not be feasible from conventional time series graphical representations. Methods We introduce a simple-to-implement visualisation method, termed dynamical density delay mapping (“D3-Map” technique) that provides an animated representation of a system’s dynamics. The method is based on a generalization of conventional two-dimensional (2D) Poincaré plots, which are scatter plots where each data point, x(n), in a time series is plotted against the adjacent one, x(n + 1). First, we divide the original time series, x(n) (n = 1,…, N), into a sequence of segments (windows). Next, for each segment, a three-dimensional (3D) Poincaré surface plot of x(n), x(n + 1), h[x(n),x(n + 1)] is generated, in which the third dimension, h, represents the relative frequency of occurrence of each (x(n),x(n + 1)) point. This 3D Poincaré surface is then chromatised by mapping the relative frequency h values onto a colour scheme. We also generate a colourised 2D contour plot from each time series segment using the same colourmap scheme as for the 3D Poincaré surface. Finally, the original time series graph, the colourised 3D Poincaré surface plot, and its projection as a colourised 2D contour map for each segment, are animated to create the full “D3-Map.” Results We first exemplify the D3-Map method using the cardiac interbeat interval time series from a healthy subject during sleeping hours. The animations uncover complex dynamical changes, such as transitions between states, and the relative amount of time the system spends in each state. We also illustrate the utility of the method in detecting hidden temporal patterns in the heart rate dynamics of a patient with atrial fibrillation. The videos, as well as the source code, are made publicly available. Conclusions Animations based on density delay maps provide a new way of visualising dynamical properties of complex systems not apparent in time series graphs or standard Poincaré plot representations. Trainees in a variety of fields may find the animations useful as illustrations of fundamental but challenging concepts, such as nonstationarity and multistability. For investigators, the method may facilitate data exploration. PMID:24438439

A compilation of K-Ar-ages for southern California

USGS Publications Warehouse

Miller, Fred K.; Morton, Douglas M.; Morton, Janet L.; Miller, David M.

2014-01-01

The purpose of this report is to make available a large body of conventional K-Ar ages for granitic, volcanic, and metamorphic rocks collected in southern California. Although one interpretive map is included, the report consists primarily of a systematic listing, without discussion or interpretation, of published and unpublished ages that may be of value in future regional and other geologic studies. From 1973 to 1979, 468 rock samples from southern California were collected for conventional K-Ar dating under a regional geologic mapping project of Southern California (predecessor of the Southern California Areal Mapping Project). Most samples were collected and dated between 1974 and 1977. For 61 samples (13 percent of those collected), either they were discarded for varying reasons, or the original collection data were lost. For the remaining samples, 518 conventional K-Ar ages are reported here; coexisting mineral pairs were dated from many samples. Of these K-Ar ages, 225 are previously unpublished, and identified as such in table 1. All K-Ar ages are by conventional K-Ar analysis; no 40Ar/39Ar dating was done. Subsequent to the rock samples collected in the 1970s and reported here, 33 samples were collected and 38 conventional K-Ar ages determined under projects directed at (1) characterization of the Mesozoic and Cenozoic igneous rocks in and on both sides of the Transverse Ranges and (2) clarifying the Mesozoic and Cenozoic tectonics of the eastern Mojave Desert. Although previously published (Beckerman et al., 1982), another eight samples and 11 conventional K-Ar ages are included here, because they augment those completed under the previous two projects.

Evaluating HDR photos using Web 2.0 technology

NASA Astrophysics Data System (ADS)

Qiu, Guoping; Mei, Yujie; Duan, Jiang

2011-01-01

High dynamic range (HDR) photography is an emerging technology that has the potential to dramatically enhance the visual quality and realism of digital photos. One of the key technical challenges of HDR photography is displaying HDR photos on conventional devices through tone mapping or dynamic range compression. Although many different tone mapping techniques have been developed in recent years, evaluating tone mapping operators prove to be extremely difficult. Web2.0, social media and crowd-sourcing are emerging Internet technologies which can be harnessed to harvest the brain power of the mass to solve difficult problems in science, engineering and businesses. Paired comparison is used in the scientific study of preferences and attitudes and has been shown to be capable of obtaining an interval-scale ordering of items along a psychometric dimension such as preference or importance. In this paper, we exploit these technologies for evaluating HDR tone mapping algorithms. We have developed a Web2.0 style system that enables Internet users from anywhere to evaluate tone mapped HDR photos at any time. We adopt a simple paired comparison protocol, Internet users are presented a pair of tone mapped images and are simply asked to select the one that they think is better or click a "no difference" button. These user inputs are collected in the web server and analyzed by a rank aggregation algorithm which ranks the tone mapped photos according to the votes they received. We present experimental results which demonstrate that the emerging Internet technologies can be exploited as a new paradigm for evaluating HDR tone mapping algorithms. The advantages of this approach include the potential of collecting large user inputs under a variety of viewing environments rather than limited user participation under controlled laboratory environments thus enabling more robust and reliable quality assessment. We also present data analysis to correlate user generated qualitative indices with quantitative image statistics which may provide useful guidance for developing better tone mapping operators.

Digital Mapping Techniques '09-Workshop Proceedings, Morgantown, West Virginia, May 10-13, 2009

USGS Publications Warehouse

Soller, David R.

2011-01-01

As in the previous years' meetings, the objective was to foster informal discussion and exchange of technical information, principally in order to develop more efficient methods for digital mapping, cartography, GIS analysis, and information management. At this meeting, oral and poster presentations and special discussion sessions emphasized (1) methods for creating and publishing map products (here, "publishing" includes Web-based release); (2) field data capture software and techniques, including the use of LiDAR; (3) digital cartographic techniques; (4) migration of digital maps into ArcGIS Geodatabase format; (5) analytical GIS techniques; and (6) continued development of the National Geologic Map Database.

Efficient low-bit-rate adaptive mesh-based motion compensation technique

NASA Astrophysics Data System (ADS)

Mahmoud, Hanan A.; Bayoumi, Magdy A.

2001-08-01

This paper proposes a two-stage global motion estimation method using a novel quadtree block-based motion estimation technique and an active mesh model. In the first stage, motion parameters are estimated by fitting block-based motion vectors computed using a new efficient quadtree technique, that divides a frame into equilateral triangle blocks using the quad-tree structure. Arbitrary partition shapes are achieved by allowing 4-to-1, 3-to-1 and 2-1 merge/combine of sibling blocks having the same motion vector . In the second stage, the mesh is constructed using an adaptive triangulation procedure that places more triangles over areas with high motion content, these areas are estimated during the first stage. finally the motion compensation is achieved by using a novel algorithm that is carried by both the encoder and the decoder to determine the optimal triangulation of the resultant partitions followed by affine mapping at the encoder. Computer simulation results show that the proposed method gives better performance that the conventional ones in terms of the peak signal-to-noise ration (PSNR) and the compression ratio (CR).

Avoiding and tolerating latency in large-scale next-generation shared-memory multiprocessors

NASA Technical Reports Server (NTRS)

Probst, David K.

1993-01-01

A scalable solution to the memory-latency problem is necessary to prevent the large latencies of synchronization and memory operations inherent in large-scale shared-memory multiprocessors from reducing high performance. We distinguish latency avoidance and latency tolerance. Latency is avoided when data is brought to nearby locales for future reference. Latency is tolerated when references are overlapped with other computation. Latency-avoiding locales include: processor registers, data caches used temporally, and nearby memory modules. Tolerating communication latency requires parallelism, allowing the overlap of communication and computation. Latency-tolerating techniques include: vector pipelining, data caches used spatially, prefetching in various forms, and multithreading in various forms. Relaxing the consistency model permits increased use of avoidance and tolerance techniques. Each model is a mapping from the program text to sets of partial orders on program operations; it is a convention about which temporal precedences among program operations are necessary. Information about temporal locality and parallelism constrains the use of avoidance and tolerance techniques. Suitable architectural primitives and compiler technology are required to exploit the increased freedom to reorder and overlap operations in relaxed models.

Comparison of digital and conventional impression techniques: evaluation of patients’ perception, treatment comfort, effectiveness and clinical outcomes

PubMed Central

2014-01-01

Background The purpose of this study was to compare two impression techniques from the perspective of patient preferences and treatment comfort. Methods Twenty-four (12 male, 12 female) subjects who had no previous experience with either conventional or digital impression participated in this study. Conventional impressions of maxillary and mandibular dental arches were taken with a polyether impression material (Impregum, 3 M ESPE), and bite registrations were made with polysiloxane bite registration material (Futar D, Kettenbach). Two weeks later, digital impressions and bite scans were performed using an intra-oral scanner (CEREC Omnicam, Sirona). Immediately after the impressions were made, the subjects’ attitudes, preferences and perceptions towards impression techniques were evaluated using a standardized questionnaire. The perceived source of stress was evaluated using the State-Trait Anxiety Scale. Processing steps of the impression techniques (tray selection, working time etc.) were recorded in seconds. Statistical analyses were performed with the Wilcoxon Rank test, and p < 0.05 was considered significant. Results There were significant differences among the groups (p < 0.05) in terms of total working time and processing steps. Patients stated that digital impressions were more comfortable than conventional techniques. Conclusions Digital impressions resulted in a more time-efficient technique than conventional impressions. Patients preferred the digital impression technique rather than conventional techniques. PMID:24479892

New Projections of Global Forest Carbon and Ecosystems at Risk for Increased Greenhouse Gas Emissions From Disturbance and Forest Degradation

NASA Astrophysics Data System (ADS)

Klooster, S.; Potter, C. S.; Genovese, V. B.; Gross, P. M.; Kumar, V.; Boriah, S.; Mithal, V.; Castilla-Rubio, J.

2009-12-01

Widely cited forest carbon values from look-up tables and statistical correlations with aboveground biomass have proven to be inadequate to discern details of national carbon stocks in forest pools. Similarly, global estimates based on biome-average (tropical, temperate, boreal, etc.) carbon measurements are generally insufficient to support REDD incentives (Reductions in Emission from Deforestation in Developing countries). The NASA-CASA (Carnegie-Ames-Stanford Approach) ecosystem model published by Potter et al. (1999 and 2003) offers several unique advantages for carbon accounting that cannot be provided by conventional inventory techniques. First, CASA uses continuous satellite observations to map land cover status and changes in vegetation on a monthly time interval over the past 25 years. NASA satellites observe areas that are too remote or rugged for conventional inventory-based techniques to measure. Second, CASA estimates both aboveground and belowground pools of carbon in all ecosystems (forests, shrublands, croplands, and rangelands). Carbon storage estimates for forests globally are currently being estimated for the Cisco Planetary Skin open collaborative platform (www.planetaryskin.org ) in a new series of CASA model runs using the latest input data from the NASA MODIS satellites, from 2000 to the present. We have also developed an approach for detection of large-scale ecosystem disturbance (LSED) events based on sustained declines in the same satellite greenness data used for CASA modeling. This approach is global in scope, covers more than a decade of observations, and encompasses all potential categories of major ecosystem disturbance - physical, biogenic, and anthropogenic, using advanced methods of data mining and analysis. In addition to quantifying forest areas at various levels of risk for loss of carbon storage capacity, our data mining approaches for LSED events can be adapted to detect and map biophysically unsuitable areas for deforestation worldwide and to develop carbon risk scoring algorithms that can enable large scale finance for conservation and reforestation efforts globally.

A study of the utilization of ERTS-1 data from the Wabash River Basin

NASA Technical Reports Server (NTRS)

Landgrebe, D. A. (Principal Investigator)

1974-01-01

The author has identified the following significant results. The identification and area estimation of crops experiment tested the usefulness of ERTS data for crop survey and produced results indicating that crop statistics could be obtained from ERTS imagery. Soil association mapping results showed that strong relationships exist between ERTS data derived maps and conventional soil maps. Urban land use analysis experiment results indicate potential for accurate gross land use mapping. Water resources mapping demonstrated the feasibility of mapping water bodies using ERTS imagery.

Clinical feasibility of using mean apparent propagator (MAP) MRI to characterize brain tissue microstructure.

PubMed

Avram, Alexandru V; Sarlls, Joelle E; Barnett, Alan S; Özarslan, Evren; Thomas, Cibu; Irfanoglu, M Okan; Hutchinson, Elizabeth; Pierpaoli, Carlo; Basser, Peter J

2016-02-15

Diffusion tensor imaging (DTI) is the most widely used method for characterizing noninvasively structural and architectural features of brain tissues. However, the assumption of a Gaussian spin displacement distribution intrinsic to DTI weakens its ability to describe intricate tissue microanatomy. Consequently, the biological interpretation of microstructural parameters, such as fractional anisotropy or mean diffusivity, is often equivocal. We evaluate the clinical feasibility of assessing brain tissue microstructure with mean apparent propagator (MAP) MRI, a powerful analytical framework that efficiently measures the probability density function (PDF) of spin displacements and quantifies useful metrics of this PDF indicative of diffusion in complex microstructure (e.g., restrictions, multiple compartments). Rotation invariant and scalar parameters computed from the MAP show consistent variation across neuroanatomical brain regions and increased ability to differentiate tissues with distinct structural and architectural features compared with DTI-derived parameters. The return-to-origin probability (RTOP) appears to reflect cellularity and restrictions better than MD, while the non-Gaussianity (NG) measures diffusion heterogeneity by comprehensively quantifying the deviation between the spin displacement PDF and its Gaussian approximation. Both RTOP and NG can be decomposed in the local anatomical frame for reference determined by the orientation of the diffusion tensor and reveal additional information complementary to DTI. The propagator anisotropy (PA) shows high tissue contrast even in deep brain nuclei and cortical gray matter and is more uniform in white matter than the FA, which drops significantly in regions containing crossing fibers. Orientational profiles of the propagator computed analytically from the MAP MRI series coefficients allow separation of different fiber populations in regions of crossing white matter pathways, which in turn improves our ability to perform whole-brain fiber tractography. Reconstructions from subsampled data sets suggest that MAP MRI parameters can be computed from a relatively small number of DWIs acquired with high b-value and good signal-to-noise ratio in clinically achievable scan durations of less than 10min. The neuroanatomical consistency across healthy subjects and reproducibility in test-retest experiments of MAP MRI microstructural parameters further substantiate the robustness and clinical feasibility of this technique. The MAP MRI metrics could potentially provide more sensitive clinical biomarkers with increased pathophysiological specificity compared to microstructural measures derived using conventional diffusion MRI techniques. Published by Elsevier Inc.

An evaluation of student and clinician perception of digital and conventional implant impressions.

PubMed

Lee, Sang J; Macarthur, Robert X; Gallucci, German O

2013-11-01

The accuracy and efficiency of digital implant impressions should match conventional impressions. Comparisons should be made with clinically relevant data. The purpose of this study was to evaluate the difficulty level and operator's perception between dental students and experienced clinicians when making digital and conventional implant impressions. Thirty experienced dental professionals and 30 second-year dental students made conventional and digital impressions of a single implant model. A visual analog scale (VAS) and multiple-choice questionnaires were used to assess the participant's perception of difficulty, preference, and effectiveness. Wilcoxon signed-rank test within the groups and Wilcoxon rank-sum test between the groups were used for statistical analysis (α=.05). On a 0 to 100 VAS, the student group scored a mean difficulty level of 43.1 (±18.5) for the conventional impression technique and 30.6 (±17.6) for the digital impression technique (P=.006). The clinician group scored a mean (standard deviation) difficulty level of 30.9 (±19.6) for conventional impressions and 36.5 (±20.6) for digital impressions (P=.280). Comparison between groups showed a mean difficulty level with the conventional impression technique significantly higher in the student group (P=.030). The digital impression was not significantly different between the groups (P=.228). Sixty percent of the students preferred the digital impression and 7% the conventional impression; 33% expressed no preference. In the clinician group, 33% preferred the digital impression and 37% the conventional impression; 30% had no preference. Seventy-seven percent of the student group felt most effective with digital impressions, 10% with conventional impressions, and 13% with either technique, whereas 40% of the clinician group chose the digital impression as the most effective technique, 53% the conventional impression, and 7% either technique. The conventional impression was more difficult to perform for the student group than the clinician group; however, the difficulty level of the digital impression was the same in both groups. It was also determined that the student group preferred the digital impression as the most efficient impression technique, and the clinician group had an even distribution in the choice of preferred and efficient impression techniques. Copyright © 2013 Editorial Council for the Journal of Prosthetic Dentistry. Published by Mosby, Inc. All rights reserved.

Mapping of forested wetland: use of Seasat radar images to complement conventional sources ( USA).

USGS Publications Warehouse

Place, J.L.

1985-01-01

Distinguishing forested wetland from dry forest using aerial photographs is handicapped because photographs often do not reveal the presence of water below tree canopies. Radar images obtained by the Seasat satellite reveal forested wetland as highly reflective patterns on the coastal plain between Maryland and Florida. Seasat radar images may complement aerial photographs for compiling maps of wetland. A test with experienced photointerpreters revealed that interpretation accuracy was significantly higher when using Seasat radar images than when using only conventional sources.-Author

A comparison of two conformal mapping techniques applied to an aerobrake body

NASA Technical Reports Server (NTRS)

Hommel, Mark J.

1987-01-01

Conformal mapping is a classical technique which has been utilized for solving problems in aerodynamics and hydrodynamics. Conformal mapping has been successfully applied in the construction of grids around airfoils, engine inlets and other aircraft configurations. Conformal mapping techniques were applied to an aerobrake body having an axis of symmetry. Two different approaches were utilized: (1) Karman-Trefftz transformation; and (2) Point Wise Schwarz Christoffel transformation. In both cases, the aerobrake body was mapped onto a near circle, and a grid was generated in the mapped plane. The mapped body and grid were then mapped back into physical space and the properties of the associated grids were examined. Advantages and disadvantages of both approaches are discussed.

Sparsity-constrained PET image reconstruction with learned dictionaries

NASA Astrophysics Data System (ADS)

Tang, Jing; Yang, Bao; Wang, Yanhua; Ying, Leslie

2016-09-01

PET imaging plays an important role in scientific and clinical measurement of biochemical and physiological processes. Model-based PET image reconstruction such as the iterative expectation maximization algorithm seeking the maximum likelihood solution leads to increased noise. The maximum a posteriori (MAP) estimate removes divergence at higher iterations. However, a conventional smoothing prior or a total-variation (TV) prior in a MAP reconstruction algorithm causes over smoothing or blocky artifacts in the reconstructed images. We propose to use dictionary learning (DL) based sparse signal representation in the formation of the prior for MAP PET image reconstruction. The dictionary to sparsify the PET images in the reconstruction process is learned from various training images including the corresponding MR structural image and a self-created hollow sphere. Using simulated and patient brain PET data with corresponding MR images, we study the performance of the DL-MAP algorithm and compare it quantitatively with a conventional MAP algorithm, a TV-MAP algorithm, and a patch-based algorithm. The DL-MAP algorithm achieves improved bias and contrast (or regional mean values) at comparable noise to what the other MAP algorithms acquire. The dictionary learned from the hollow sphere leads to similar results as the dictionary learned from the corresponding MR image. Achieving robust performance in various noise-level simulation and patient studies, the DL-MAP algorithm with a general dictionary demonstrates its potential in quantitative PET imaging.

Inter-Slice Blood Flow and Magnetization Transfer Effects as A New Simultaneous Imaging Strategy.

PubMed

Han, Paul Kyu; Barker, Jeffrey W; Kim, Ki Hwan; Choi, Seung Hong; Bae, Kyongtae Ty; Park, Sung-Hong

2015-01-01

The recent blood flow and magnetization transfer (MT) technique termed alternate ascending/descending directional navigation (ALADDIN) achieves the contrast using interslice blood flow and MT effects with no separate preparation RF pulse, thereby potentially overcoming limitations of conventional methods. In this study, we examined the signal characteristics of ALADDIN as a simultaneous blood flow and MT imaging strategy, by comparing it with pseudo-continuous ASL (pCASL) and conventional MT asymmetry (MTA) methods, all of which had the same bSSFP readout. Bloch-equation simulations and experiments showed ALADDIN perfusion signals increased with flip angle, whereas MTA signals peaked at flip angle around 45°-60°. ALADDIN provided signals comparable to those of pCASL and conventional MTA methods emulating the first, second, and third prior slices of ALADDIN under the same scan conditions, suggesting ALADDIN signals to be superposition of signals from multiple labeling planes. The quantitative cerebral blood flow signals from a modified continuous ASL model overestimated the perfusion signals compared to those measured with a pulsed ASL method. Simultaneous mapping of blood flow, MTA, and MT ratio in the whole brain is feasible with ALADDIN within a clinically reasonable time, which can potentially help diagnosis of various diseases.

GeoInformation studies of soil and vegetation patterns along Climatic Gradients: A Review

NASA Astrophysics Data System (ADS)

Shoshany, M.

2009-04-01

Global evidence regarding magnitudes of desertification processes and recognition in their societal, ecological and climatological consequences had lead the international community to establish the United Nations Convention to Combat Desertification (UNCCD). Within the framework of this convention it is perceived that Desertification is a complex poorly understood phenomena which is " first and foremost, the result of resource management failures". Scientific research within this context have three primary roles: monitoring the situation, developing the understanding of relationships between factors promoting desertification and finally providing the international community with efficient recommendations regarding actions which may slow down these processes. Study of desertification processes in regions of sharp climatic gradients is of special importance within this framework since they represent areas where the processes are most intensive and where most deserts actually expand. The detection of threshold zones coupling sever land degradation with loss of resilience in their eco-geomophic systems is fundamental for the efficient combating of global desertification. Application of geoinformation tools and techniques is instrumental for this purpose: mapping biological, chemical and physical surface properties using remote sensing techniques, mapping historical patch-pattern changes using air-photographs, analysis of spatio-temporal variations in pattern properties and analysis of informational relationships between these surface properties and patterns with climatoloical, topographic, lithological and human factors. Numerous Remote Sensing studies had been undertaken during the last four decades in monitoring desertification through the provision of maps describing spatial distributions of biophysical surface parameters at resolutions between few meters to few kilometers and temporal resolutions between hours and weeks. These studies utilized radar backscattering , spectral reflectance at the visible, NIR and SWIR ranges and emissions in the thermal spectrum. However, despite the magnitude of these projects very few of the methods were proved to be operational yet. The main shortcomings of exiting methods are: - They are highly dependent on accurate calibration which for large region is impractical. - Most of the methods are semi-empirical: case dependent rather than representing robust physical indicators. - There is no one imagery source which is good for all mapping purposes, most of the methods use single imagery source and there is relatively little synergy (fusion) between imagery sources. - Data continuity for long time periods exits mainly for low resolution sources which are limited in supporting modeling of processes. - Difficulties in scaling-up results and methods from the local to the broad-regional scales Within the scope of interest here the most important shortcoming concern the fact that relatively little work treated explicitly regions of high climatic gradient partly due to their high spatio-temporal heterogeneity. Three areas of recent advancements in studying explicitly transition zones between humid and arid regions : - Mapping bio-physical properties of vegetation forms (herbaceous, dwarf-shrubs and shrubs): cover proportions, biomass, primary productivity using synergy between optical (phonologies) and SAR imagery. - Mapping chemical and physical soil properties and estimating their erodibility using hyper and multi spectral methods, and SAR backscattering. - Mapping soil and vegetation patch patterns and their changes within the last decades using historical air-photographs. These advancement s lead to the detection of threshold zones between regions along these gradients according to following indicators: - Life-forms compositions, biomass and primary productivity. Analysis of relationships between biomass and rainfall allow differentiation between cases were vegetation compositions and properties which follow 'expected' successional sequences and those which represent harsh land degradation with productivity significantly less than would be expected according to their average annual precipitation. - Soil chemical compositions referring mainly to organic carbon, inorganic carbon and ferrum. These mapping allowed the detection of 'tipping points' in the high transition zones. Analysis of historical patch-patterns ' evolution modes using air-photographs and GIS techniques allowed insight into soil and vegetation pattern dynamics. Recent results had revealed that in some areas of low biomass there is maintained similar pattern fragmentation as in areas of higher rainfall. This signifies the functioning of self-organization and consequently the potential resilience of some areas of relatively low primary productivity located at desert margins. In conclusion, current geoinformation tools and techniques on one hand had shown their potential contribution to the modeling and understanding of desertification processes in general and the formation of thresholds through the functioning of 'tipping' mechanisms and 'catastrophic shifts'. However, these tools and techniques are not yet operational at the wide regional scale. Better synergy of remote sensing sources and availability of longer time series of surface properties will facilitate the combat of desertification with both better understanding of the processes and predictions of expected spatial change in different warming and human disturbance scenarios.

Comparative Evaluation of Conventional and Accelerated Castings on Marginal Fit and Surface Roughness

PubMed Central

Jadhav, Vivek Dattatray; Motwani, Bhagwan K.; Shinde, Jitendra; Adhapure, Prasad

2017-01-01

Aims: The aim of this study was to evaluate the marginal fit and surface roughness of complete cast crowns made by a conventional and an accelerated casting technique. Settings and Design: This study was divided into three parts. In Part I, the marginal fit of full metal crowns made by both casting techniques in the vertical direction was checked, in Part II, the fit of sectional metal crowns in the horizontal direction made by both casting techniques was checked, and in Part III, the surface roughness of disc-shaped metal plate specimens made by both casting techniques was checked. Materials and Methods: A conventional technique was compared with an accelerated technique. In Part I of the study, the marginal fit of the full metal crowns as well as in Part II, the horizontal fit of sectional metal crowns made by both casting techniques was determined, and in Part III, the surface roughness of castings made with the same techniques was compared. Statistical Analysis Used: The results of the t-test and independent sample test do not indicate statistically significant differences in the marginal discrepancy detected between the two casting techniques. Results: For the marginal discrepancy and surface roughness, crowns fabricated with the accelerated technique were significantly different from those fabricated with the conventional technique. Conclusions: Accelerated casting technique showed quite satisfactory results, but the conventional technique was superior in terms of marginal fit and surface roughness. PMID:29042726

Comparison of the fit of cast gold crowns fabricated from the digital and the conventional impression techniques

PubMed Central

Jeon, Young-Chan; Jeong, Chang-Mo

2017-01-01

PURPOSE The purpose of this study was to compare the fit of cast gold crowns fabricated from the conventional and the digital impression technique. MATERIALS AND METHODS Artificial tooth in a master model and abutment teeth in ten patients were restored with cast gold crowns fabricated from the digital and the conventional impression technique. The forty silicone replicas were cut in three sections; each section was evaluated in nine points. The measurement was carried out by using a measuring microscope and I-Soultion. Data from the silicone replica were analyzed and all tests were performed with α-level of 0.05. RESULTS 1. The average gaps of cast gold crowns fabricated from the digital impression technique were larger than those of the conventional impression technique significantly. 2. In marginal and internal axial gap of cast gold crowns, no statistical differences were found between the two impression techniques. 3. The internal occlusal gaps of cast gold crowns fabricated from the digital impression technique were larger than those of the conventional impression technique significantly. CONCLUSION Both prostheses presented clinically acceptable results with comparing the fit. The prostheses fabricated from the digital impression technique showed more gaps, in respect of occlusal surface. PMID:28243386

Conventions and workflows for using Situs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wriggers, Willy, E-mail: wriggers@biomachina.org

2012-04-01

Recent developments of the Situs software suite for multi-scale modeling are reviewed. Typical workflows and conventions encountered during processing of biophysical data from electron microscopy, tomography or small-angle X-ray scattering are described. Situs is a modular program package for the multi-scale modeling of atomic resolution structures and low-resolution biophysical data from electron microscopy, tomography or small-angle X-ray scattering. This article provides an overview of recent developments in the Situs package, with an emphasis on workflows and conventions that are important for practical applications. The modular design of the programs facilitates scripting in the bash shell that allows specific programs tomore » be combined in creative ways that go beyond the original intent of the developers. Several scripting-enabled functionalities, such as flexible transformations of data type, the use of symmetry constraints or the creation of two-dimensional projection images, are described. The processing of low-resolution biophysical maps in such workflows follows not only first principles but often relies on implicit conventions. Situs conventions related to map formats, resolution, correlation functions and feature detection are reviewed and summarized. The compatibility of the Situs workflow with CCP4 conventions and programs is discussed.« less

Beam modulation: A novel ToF-technique for high resolution diffraction at the Beamline for European Materials Engineering Research (BEER)

NASA Astrophysics Data System (ADS)

Rouijaa, M.; Kampmann, R.; Šaroun, J.; Fenske, J.; Beran, P.; Müller, M.; Lukáš, P.; Schreyer, A.

2018-05-01

The Beamline for European Materials Engineering Research (BEER) is under construction at the European Spallation Source (ESS) in Lund, Sweden. A basic requirement on BEER is to make best use of the long ESS pulse (2.86 ms) for engineering investigations. High-resolution diffraction, however, demands timing resolution up to 0.1% corresponding to a pulse length down to about 70 μs for the case of thermal neutrons (λ ∼ 1.8 Å). Such timing resolution can be achieved by pulse shaping techniques cutting a short section out of the long pulse, and thus paying for resolution by strong loss of intensity. In contrast to this, BEER proposes a novel operation mode called pulse modulation technique based on a new chopper design, which extracts several short pulses out of the long ESS pulse, and hence leads to a remarkable gain of intensity compared to nowadays existing conventional pulse shaping techniques. The potential of the new technique can be used with full advantage for investigating strains and textures of highly symmetric materials. Due to its instrument design and the high brilliance of the ESS pulse, BEER is expected to become the European flagship for engineering research for strain mapping and texture analysis.

Mapping piezoelectric response in nanomaterials using a dedicated non-destructive scanning probe technique.

PubMed

Calahorra, Yonatan; Smith, Michael; Datta, Anuja; Benisty, Hadas; Kar-Narayan, Sohini

2017-12-14

There has been tremendous interest in piezoelectricity at the nanoscale, for example in nanowires and nanofibers where piezoelectric properties may be enhanced or controllably tuned, thus necessitating robust characterization techniques of piezoelectric response in nanomaterials. Piezo-response force microscopy (PFM) is a well-established scanning probe technique routinely used to image piezoelectric/ferroelectric domains in thin films, however, its applicability to nanoscale objects is limited due to the requirement for physical contact with an atomic force microscope (AFM) tip that may cause dislocation or damage, particularly to soft materials, during scanning. Here we report a non-destructive PFM (ND-PFM) technique wherein the tip is oscillated into "discontinuous" contact during scanning, while applying an AC bias between tip and sample and extracting the piezoelectric response for each contact point by monitoring the resulting localized deformation at the AC frequency. ND-PFM is successfully applied to soft polymeric (poly-l-lactic acid) nanowires, as well as hard ceramic (barium zirconate titanate-barium calcium titanate) nanowires, both previously inaccessible by conventional PFM. Our ND-PFM technique is versatile and compatible with commercial AFMs, and can be used to correlate piezoelectric properties of nanomaterials with their microstructural features thus overcoming key characterisation challenges in the field.

Doppler synthetic aperture radar interferometry: a novel SAR interferometry for height mapping using ultra-narrowband waveforms

NASA Astrophysics Data System (ADS)

Yazıcı, Birsen; Son, Il-Young; Cagri Yanik, H.

2018-05-01

This paper introduces a new and novel radar interferometry based on Doppler synthetic aperture radar (Doppler-SAR) paradigm. Conventional SAR interferometry relies on wideband transmitted waveforms to obtain high range resolution. Topography of a surface is directly related to the range difference between two antennas configured at different positions. Doppler-SAR is a novel imaging modality that uses ultra-narrowband continuous waves (UNCW). It takes advantage of high resolution Doppler information provided by UNCWs to form high resolution SAR images. We introduce the theory of Doppler-SAR interferometry. We derive an interferometric phase model and develop the equations of height mapping. Unlike conventional SAR interferometry, we show that the topography of a scene is related to the difference in Doppler frequency between two antennas configured at different velocities. While the conventional SAR interferometry uses range, Doppler and Doppler due to interferometric phase in height mapping; Doppler-SAR interferometry uses Doppler, Doppler-rate and Doppler-rate due to interferometric phase in height mapping. We demonstrate our theory in numerical simulations. Doppler-SAR interferometry offers the advantages of long-range, robust, environmentally friendly operations; low-power, low-cost, lightweight systems suitable for low-payload platforms, such as micro-satellites; and passive applications using sources of opportunity transmitting UNCW.

Cognitive Mapping Techniques: Implications for Research in Engineering and Technology Education

ERIC Educational Resources Information Center

Dixon, Raymond A.; Lammi, Matthew

2014-01-01

The primary goal of this paper is to present the theoretical basis and application of two types of cognitive maps, concept map and mind map, and explain how they can be used by educational researchers in engineering design research. Cognitive mapping techniques can be useful to researchers as they study students' problem solving strategies…

Impact of Indocyanine Green for Sentinel Lymph Node Mapping in Early Stage Endometrial and Cervical Cancer: Comparison with Conventional Radiotracer (99m)Tc and/or Blue Dye.

PubMed

Buda, Alessandro; Crivellaro, Cinzia; Elisei, Federica; Di Martino, Giampaolo; Guerra, Luca; De Ponti, Elena; Cuzzocrea, Marco; Giuliani, Daniela; Sina, Federica; Magni, Sonia; Landoni, Claudio; Milani, Rodolfo

2016-07-01

To compare the detection rate (DR) and bilateral optimal mapping (OM) of sentinel lymph nodes (SLNs) in women with endometrial and cervical cancer using indocyanine green (ICG) versus the standard technetium-99m radiocolloid ((99m)Tc) radiotracer plus methylene or isosulfan blue, or blue dye alone. From October 2010 to May 2015, 163 women with stage I endometrial or cervical cancer (118 endometrial and 45 cervical cancer) underwent SLN mapping with (99m)Tc with blue dye, blue dye alone, or ICG. DR and bilateral OM of ICG were compared respectively with the results obtained using the standard (99m)Tc radiotracer with blue dye, or blue dye alone. SLN mapping with (99m)Tc radiotracer with blue dye was performed on 77 of 163 women, 38 with blue dye only and 48 with ICG. The overall DR of SLN mapping was 97, 89, and 100 % for (99m)Tc with blue dye, blue dye alone, and ICG, respectively. The bilateral OM rate for ICG was 85 %-significantly higher than the 58 % obtained with (99m)Tc with blue dye (p = 0.003) and the 54 % for blue dye (p = 0.001). Thirty-one women (19 %) had positive SLNs. Sensitivity and negative predictive value of SLN were 100 % for all techniques. SLNs mapping using ICG demonstrated higher DR compared to other modalities. In addition, ICG was significantly superior to (99m)Tc with blue dye in terms of bilateral OM in women with early stage endometrial and cervical cancer. The higher number of bilateral OM may consequently reduce the overall number of complete lymphadenectomies, reducing the duration and additional costs of surgical treatment.

Historical shoreline mapping (I): improving techniques and reducing positioning errors

USGS Publications Warehouse

Thieler, E. Robert; Danforth, William W.

1994-01-01

A critical need exists among coastal researchers and policy-makers for a precise method to obtain shoreline positions from historical maps and aerial photographs. A number of methods that vary widely in approach and accuracy have been developed to meet this need. None of the existing methods, however, address the entire range of cartographic and photogrammetric techniques required for accurate coastal mapping. Thus, their application to many typical shoreline mapping problems is limited. In addition, no shoreline mapping technique provides an adequate basis for quantifying the many errors inherent in shoreline mapping using maps and air photos. As a result, current assessments of errors in air photo mapping techniques generally (and falsely) assume that errors in shoreline positions are represented by the sum of a series of worst-case assumptions about digitizer operator resolution and ground control accuracy. These assessments also ignore altogether other errors that commonly approach ground distances of 10 m. This paper provides a conceptual and analytical framework for improved methods of extracting geographic data from maps and aerial photographs. We also present a new approach to shoreline mapping using air photos that revises and extends a number of photogrammetric techniques. These techniques include (1) developing spatially and temporally overlapping control networks for large groups of photos; (2) digitizing air photos for use in shoreline mapping; (3) preprocessing digitized photos to remove lens distortion and film deformation effects; (4) simultaneous aerotriangulation of large groups of spatially and temporally overlapping photos; and (5) using a single-ray intersection technique to determine geographic shoreline coordinates and express the horizontal and vertical error associated with a given digitized shoreline. As long as historical maps and air photos are used in studies of shoreline change, there will be a considerable amount of error (on the order of several meters) present in shoreline position and rate-of- change calculations. The techniques presented in this paper, however, provide a means to reduce and quantify these errors so that realistic assessments of the technological noise (as opposed to geological noise) in geographic shoreline positions can be made.

Conditional Random Field-Based Offline Map Matching for Indoor Environments

PubMed Central

Bataineh, Safaa; Bahillo, Alfonso; Díez, Luis Enrique; Onieva, Enrique; Bataineh, Ikram

2016-01-01

In this paper, we present an offline map matching technique designed for indoor localization systems based on conditional random fields (CRF). The proposed algorithm can refine the results of existing indoor localization systems and match them with the map, using loose coupling between the existing localization system and the proposed map matching technique. The purpose of this research is to investigate the efficiency of using the CRF technique in offline map matching problems for different scenarios and parameters. The algorithm was applied to several real and simulated trajectories of different lengths. The results were then refined and matched with the map using the CRF algorithm. PMID:27537892

Conditional Random Field-Based Offline Map Matching for Indoor Environments.

PubMed

Bataineh, Safaa; Bahillo, Alfonso; Díez, Luis Enrique; Onieva, Enrique; Bataineh, Ikram

2016-08-16

In this paper, we present an offline map matching technique designed for indoor localization systems based on conditional random fields (CRF). The proposed algorithm can refine the results of existing indoor localization systems and match them with the map, using loose coupling between the existing localization system and the proposed map matching technique. The purpose of this research is to investigate the efficiency of using the CRF technique in offline map matching problems for different scenarios and parameters. The algorithm was applied to several real and simulated trajectories of different lengths. The results were then refined and matched with the map using the CRF algorithm.

Validation of projective mapping as potential sensory screening tool for application by the honeybush herbal tea industry.

PubMed

Moelich, Erika Ilette; Muller, Magdalena; Joubert, Elizabeth; Næs, Tormod; Kidd, Martin

2017-09-01

Honeybush herbal tea is produced from the endemic South African Cyclopia species. Plant material subjected to a high-temperature oxidation step ("fermentation") forms the bulk of production. Production lags behind demand forcing tea merchants to use blends of available material to supply local and international markets. The distinct differences in the sensory profiles of the herbal tea produced from the different Cyclopia species require that special care is given to blending to ensure a consistent, high quality product. Although conventional descriptive sensory analysis (DSA) is highly effective in providing a detailed sensory profile of herbal tea infusions, industry requires a method that is more time- and cost-effective. Recent advances in sensory science have led to the development of rapid profiling methodologies. The question is whether projective mapping can successfully be used for the sensory characterisation of herbal tea infusions. Trained assessors performed global and partial projective mapping to determine the validity of this technique for the sensory characterisation of infusions of five Cyclopia species. Similar product configurations were obtained when comparing results of DSA and global and partial projective mapping. Comparison of replicate sessions showed RV coefficients >0.8. A similarity index, based on multifactor analysis, was calculated to determine assessor repeatability. Global projective mapping, demonstrated to be a valid method for providing a broad sensory characterisation of Cyclopia species, is thus suitable as a rapid quality control method of honeybush infusions. Its application by the honeybush industry could improve the consistency of the sensory profile of blended products. Copyright © 2017 Elsevier Ltd. All rights reserved.

Development of Kinematic 3D Laser Scanning System for Indoor Mapping and As-Built BIM Using Constrained SLAM

PubMed Central

Jung, Jaehoon; Yoon, Sanghyun; Ju, Sungha; Heo, Joon

2015-01-01

The growing interest and use of indoor mapping is driving a demand for improved data-acquisition facility, efficiency and productivity in the era of the Building Information Model (BIM). The conventional static laser scanning method suffers from some limitations on its operability in complex indoor environments, due to the presence of occlusions. Full scanning of indoor spaces without loss of information requires that surveyors change the scanner position many times, which incurs extra work for registration of each scanned point cloud. Alternatively, a kinematic 3D laser scanning system, proposed herein, uses line-feature-based Simultaneous Localization and Mapping (SLAM) technique for continuous mapping. Moreover, to reduce the uncertainty of line-feature extraction, we incorporated constrained adjustment based on an assumption made with respect to typical indoor environments: that the main structures are formed of parallel or orthogonal line features. The superiority of the proposed constrained adjustment is its reduction for uncertainties of the adjusted lines, leading to successful data association process. In the present study, kinematic scanning with and without constrained adjustment were comparatively evaluated in two test sites, and the results confirmed the effectiveness of the proposed system. The accuracy of the 3D mapping result was additionally evaluated by comparison with the reference points acquired by a total station: the Euclidean average distance error was 0.034 m for the seminar room and 0.043 m for the corridor, which satisfied the error tolerance for point cloud acquisition (0.051 m) according to the guidelines of the General Services Administration for BIM accuracy. PMID:26501292

A computer-oriented system for assembling and displaying land management information

Treesearch

Elliot L. Amidon

1964-01-01

Maps contain information basic to land management planning. By transforming conventional map symbols into numbers which are punched into cards, the land manager can have a computer assemble and display information required for a specific job. He can let a computer select information from several maps, combine it with such nonmap data as treatment cost or benefit per...

Environmental psychology: Mapping landscape meanings for ecosystem management

Treesearch

Daniel R. Williams; Michael E. Patterson

1999-01-01

An intellectual map is a good starting point for any effort to integrate research on the human dimensions of ecosystem management. We must remember going into such exercises, however, that every map maker imposes a certain point of view, sense of order, or set of conventions in the effort to represent the world. Just as there are competing ways to divide the landscape...

Digital Mapping Techniques '07 - Workshop Proceedings

USGS Publications Warehouse

Soller, David R.

2008-01-01

The Digital Mapping Techniques '07 (DMT'07) workshop was attended by 85 technical experts from 49 agencies, universities, and private companies, including representatives from 27 state geological surveys. This year's meeting, the tenth in the annual series, was hosted by the South Carolina Geological Survey, from May 20-23, 2007, on the University of South Carolina campus in Columbia, South Carolina. Each DMT workshop has been coordinated by the U.S. Geological Survey's National Geologic Map Database Project and the Association of American State Geologists (AASG). As in previous year's meetings, the objective was to foster informal discussion and exchange of technical information, principally in order to develop more efficient methods for digital mapping, cartography, GIS analysis, and information management. At this meeting, oral and poster presentations and special discussion sessions emphasized: 1) methods for creating and publishing map products (here, 'publishing' includes Web-based release); 2) field data capture software and techniques, including the use of LIDAR; 3) digital cartographic techniques; 4) migration of digital maps into ArcGIS Geodatabase format; 5) analytical GIS techniques; and 6) continued development of the National Geologic Map Database.

Modeling a color-rendering operator for high dynamic range images using a cone-response function

NASA Astrophysics Data System (ADS)

Choi, Ho-Hyoung; Kim, Gi-Seok; Yun, Byoung-Ju

2015-09-01

Tone-mapping operators are the typical algorithms designed to produce visibility and the overall impression of brightness, contrast, and color of high dynamic range (HDR) images on low dynamic range (LDR) display devices. Although several new tone-mapping operators have been proposed in recent years, the results of these operators have not matched those of the psychophysical experiments based on the human visual system. A color-rendering model that is a combination of tone-mapping and cone-response functions using an XYZ tristimulus color space is presented. In the proposed method, the tone-mapping operator produces visibility and the overall impression of brightness, contrast, and color in HDR images when mapped onto relatively LDR devices. The tone-mapping resultant image is obtained using chromatic and achromatic colors to avoid well-known color distortions shown in the conventional methods. The resulting image is then processed with a cone-response function wherein emphasis is placed on human visual perception (HVP). The proposed method covers the mismatch between the actual scene and the rendered image based on HVP. The experimental results show that the proposed method yields an improved color-rendering performance compared to conventional methods.

Monitoring the bending and twist of morphing structures

NASA Astrophysics Data System (ADS)

Smoker, J.; Baz, A.

2008-03-01

This paper presents the development of the theoretical basis for the design of sensor networks for determining the 2-dimensioal shape of morphing structures by monitoring simultaneously the bending and twist deflections. The proposed development is based on the non-linear theory of finite elements to extract the transverse linear and angular deflections of a plate-like structure. The sensors outputs are wirelessly transmitted to the command unit to simultaneously compute maps of the linear and angular deflections and maps of the strain distribution of the entire structure. The deflection and shape information are required to ascertain that the structure is properly deployed and that its surfaces are operating wrinkle-free. The strain map ensures that the structure is not loaded excessively to adversely affect its service life. The developed theoretical model is validated experimentally using a prototype of a variable cambered span morphing structure provided with a network of distributed sensors. The structure/sensor network system is tested under various static conditions to determine the response characteristics of the proposed sensor network as compared to other conventional sensor systems. The presented theoretical and experimental techniques can have a great impact on the safe deployment and effective operation of a wide variety of morphing and inflatable structures such as morphing aircraft, solar sails, inflatable wings, and large antennas.

Retrieving Precise Three-Dimensional Deformation on the 2014 M6.0 South Napa Earthquake by Joint Inversion of Multi-Sensor SAR.

PubMed

Jo, Min-Jeong; Jung, Hyung-Sup; Yun, Sang-Ho

2017-07-14

We reconstructed the three-dimensional (3D) surface displacement field of the 24 August 2014 M6.0 South Napa earthquake using SAR data from the Italian Space Agency's COSMO-SkyMed and the European Space Agency's Sentinel-1A satellites. Along-track and cross-track displacements produced with conventional SAR interferometry (InSAR) and multiple-aperture SAR interferometry (MAI) techniques were integrated to retrieve the east, north, and up components of surface deformation. The resulting 3D displacement maps clearly delineated the right-lateral shear motion of the fault rupture with a maximum surface displacement of approximately 45 cm along the fault's strike, showing the east and north components of the trace particularly clearly. These maps also suggested a better-constrained model for the South Napa earthquake. We determined a strike of approximately 338° and dip of 85° by applying the Okada dislocation model considering a single patch with a homogeneous slip motion. Using the distributed slip model obtained by a linear solution, we estimated that a peak slip of approximately 1.7 m occurred around 4 km depth from the surface. 3D modelling using the retrieved 3D maps helps clarify the fault's nature and thus characterize its behaviour.

Intraosseous anesthesia with solution injection controlled by a computerized system versus conventional oral anesthesia: a preliminary study.

PubMed

Beneito-Brotons, Rut; Peñarrocha-Oltra, David; Ata-Ali, Javier; Peñarrocha, María

2012-05-01

To compare a computerized intraosseous anesthesia system with the conventional oral anesthesia techniques, and analyze the latency and duration of the anesthetic effect and patient preference. A simple-blind prospective study was made between March 2007 and May 2008. Each patient was subjected to two anesthetic techniques: conventional and intraosseous using the Quicksleeper® system (DHT, Cholet, France). A split-mouth design was adopted in which each patient underwent treatment of a tooth with one of the techniques, and treatment of the homologous contralateral tooth with the other technique. The treatments consisted of restorations, endodontic procedures and simple extractions. The study series comprised 12 females and 18 males with a mean age of 36.8 years. The 30 subjects underwent a total of 60 anesthetic procedures. Intraosseous and conventional oral anesthesia caused discomfort during administration in 46.3% and 32.1% of the patients, respectively. The latency was 7.1±2.23 minutes for the conventional technique and 0.48±0.32 for intraosseous anesthesia--the difference being statistically significant. The depth of the anesthetic effect was sufficient to allow the patients to tolerate the dental treatments. The duration of the anesthetic effect in soft tissues was 199.3 minutes with the conventional technique versus only 1.6 minutes with intraosseous anesthesia--the difference between the two techniques being statistically significant. Most of the patients (69.7%) preferred intraosseous anesthesia. The described intraosseous anesthetic system is effective, with a much shorter latency than the conventional technique, sufficient duration of anesthesia to perform the required dental treatments, and with a much lesser soft tissue anesthetic effect. Most of the patients preferred intraosseous anesthesia.

Computer-assisted versus conventional free fibula flap technique for craniofacial reconstruction: an outcomes comparison.

PubMed

Seruya, Mitchel; Fisher, Mark; Rodriguez, Eduardo D

2013-11-01

There has been rising interest in computer-aided design/computer-aided manufacturing for preoperative planning and execution of osseous free flap reconstruction. The purpose of this study was to compare outcomes between computer-assisted and conventional fibula free flap techniques for craniofacial reconstruction. A two-center, retrospective review was carried out on patients who underwent fibula free flap surgery for craniofacial reconstruction from 2003 to 2012. Patients were categorized by the type of reconstructive technique: conventional (between 2003 and 2009) or computer-aided design/computer-aided manufacturing (from 2010 to 2012). Demographics, surgical factors, and perioperative and long-term outcomes were compared. A total of 68 patients underwent microsurgical craniofacial reconstruction: 58 conventional and 10 computer-aided design and manufacturing fibula free flaps. By demographics, patients undergoing the computer-aided design/computer-aided manufacturing method were significantly older and had a higher rate of radiotherapy exposure compared with conventional patients. Intraoperatively, the median number of osteotomies was significantly higher (2.0 versus 1.0, p=0.002) and the median ischemia time was significantly shorter (120 minutes versus 170 minutes, p=0.004) for the computer-aided design/computer-aided manufacturing technique compared with conventional techniques; operative times were shorter for patients undergoing the computer-aided design/computer-aided manufacturing technique, although this did not reach statistical significance. Perioperative and long-term outcomes were equivalent for the two groups, notably, hospital length of stay, recipient-site infection, partial and total flap loss, and rate of soft-tissue and bony tissue revisions. Microsurgical craniofacial reconstruction using a computer-assisted fibula flap technique yielded significantly shorter ischemia times amidst a higher number of osteotomies compared with conventional techniques. Therapeutic, III.

Intraosseous anesthesia with solution injection controlled by a computerized system versus conventional oral anesthesia: A preliminary study

PubMed Central

Beneito-Brotons, Rut; Peñarrocha-Oltra, David; Ata-Ali, Javier

2012-01-01

Objective: To compare a computerized intraosseous anesthesia system with the conventional oral anesthesia techniques, and analyze the latency and duration of the anesthetic effect and patient preference. Design: A simple-blind prospective study was made between March 2007 and May 2008. Each patient was subjected to two anesthetic techniques: conventional and intraosseous using the Quicksleeper® system (DHT, Cholet, France). A split-mouth design was adopted in which each patient underwent treatment of a tooth with one of the techniques, and treatment of the homologous contralateral tooth with the other technique. The treatments consisted of restorations, endodontic procedures and simple extractions. Results: The study series comprised 12 females and 18 males with a mean age of 36.8 years. The 30 subjects underwent a total of 60 anesthetic procedures. Intraosseous and conventional oral anesthesia caused discomfort during administration in 46.3% and 32.1% of the patients, respectively. The latency was 7.1±2.23 minutes for the conventional technique and 0.48±0.32 for intraosseous anesthesia – the difference being statistically significant. The depth of the anesthetic effect was sufficient to allow the patients to tolerate the dental treatments. The duration of the anesthetic effect in soft tissues was 199.3 minutes with the conventional technique versus only 1.6 minutes with intraosseous anesthesia – the difference between the two techniques being statistically significant. Most of the patients (69.7%) preferred intraosseous anesthesia. Conclusions: The described intraosseous anesthetic system is effective, with a much shorter latency than the conventional technique, sufficient duration of anesthesia to perform the required dental treatments, and with a much lesser soft tissue anesthetic effect. Most of the patients preferred intraosseous anesthesia. Key words:Anesthesia, intraosseous, oral anesthesia, infiltrating, mandibular block, Quicksleeper®. PMID:22143722

Electromechanical Wave Imaging (EWI) validation in all four cardiac chambers with 3D electroanatomic mapping in canines in vivo

PubMed Central

Costet, Alexandre; Wan, Elaine; Bunting, Ethan; Grondin, Julien; Garan, Hasan; Konofagou, Elisa

2016-01-01

Characterization and mapping of arrhythmias is currently performed through invasive insertion and manipulation of cardiac catheters. Electromechanical wave imaging (EWI) is a non-invasive ultrasound-based imaging technique, which tracks the electromechanical activation that immediately follows electrical activation. Electrical and electromechanical activations were previously found to be linearly correlated in the left ventricle, but the relationship has not yet been investigated in the three other chambers of the heart. The objective of this study was to investigate the relationship between electrical and electromechanical activations and validate EWI in all four chambers of the heart with conventional 3D electroanatomical mapping. Six (n = 6) normal adult canines were used in this study. The electrical activation sequence was mapped in all four chambers of the heart, both endocardially and epicardially using the St Jude's EnSite 3D mapping system (St. Jude Medical, Secaucus, NJ). EWI acquisitions were performed in all four chambers during normal sinus rhythm, and during pacing in the left ventricle. Isochrones of the electromechanical activation were generated from standard echocardiographic imaging views. Electrical and electromechanical activation maps were co-registered and compared, and electrical and electromechanical activation times were plotted against each other and linear regression was performed for each pair of activation maps. Electromechanical and electrical activations were found to be directly correlated with slopes of the correlation ranging from 0.77 to 1.83, electromechanical delays between 9 and 58 ms and R2 values from 0.71 to 0.92. The linear correlation between electrical and electromechanical activations and the agreement between the activation maps indicate that the electromechanical activation follows the pattern of propagation of the electrical activation. This suggests that EWI may be used as a novel non-invasive method to accurately characterize and localize sources of arrhythmias. PMID:27782003

Electromechanical wave imaging (EWI) validation in all four cardiac chambers with 3D electroanatomic mapping in canines in vivo.

PubMed

Costet, Alexandre; Wan, Elaine; Bunting, Ethan; Grondin, Julien; Garan, Hasan; Konofagou, Elisa

2016-11-21

Characterization and mapping of arrhythmias is currently performed through invasive insertion and manipulation of cardiac catheters. Electromechanical wave imaging (EWI) is a non-invasive ultrasound-based imaging technique, which tracks the electromechanical activation that immediately follows electrical activation. Electrical and electromechanical activations were previously found to be linearly correlated in the left ventricle, but the relationship has not yet been investigated in the three other chambers of the heart. The objective of this study was to investigate the relationship between electrical and electromechanical activations and validate EWI in all four chambers of the heart with conventional 3D electroanatomical mapping. Six (n  =  6) normal adult canines were used in this study. The electrical activation sequence was mapped in all four chambers of the heart, both endocardially and epicardially using the St Jude's EnSite 3D mapping system (St. Jude Medical, Secaucus, NJ). EWI acquisitions were performed in all four chambers during normal sinus rhythm, and during pacing in the left ventricle. Isochrones of the electromechanical activation were generated from standard echocardiographic imaging views. Electrical and electromechanical activation maps were co-registered and compared, and electrical and electromechanical activation times were plotted against each other and linear regression was performed for each pair of activation maps. Electromechanical and electrical activations were found to be directly correlated with slopes of the correlation ranging from 0.77 to 1.83, electromechanical delays between 9 and 58 ms and R 2 values from 0.71 to 0.92. The linear correlation between electrical and electromechanical activations and the agreement between the activation maps indicate that the electromechanical activation follows the pattern of propagation of the electrical activation. This suggests that EWI may be used as a novel non-invasive method to accurately characterize and localize sources of arrhythmias.

Vastly accelerated linear least-squares fitting with numerical optimization for dual-input delay-compensated quantitative liver perfusion mapping.

PubMed

Jafari, Ramin; Chhabra, Shalini; Prince, Martin R; Wang, Yi; Spincemaille, Pascal

2018-04-01

To propose an efficient algorithm to perform dual input compartment modeling for generating perfusion maps in the liver. We implemented whole field-of-view linear least squares (LLS) to fit a delay-compensated dual-input single-compartment model to very high temporal resolution (four frames per second) contrast-enhanced 3D liver data, to calculate kinetic parameter maps. Using simulated data and experimental data in healthy subjects and patients, whole-field LLS was compared with the conventional voxel-wise nonlinear least-squares (NLLS) approach in terms of accuracy, performance, and computation time. Simulations showed good agreement between LLS and NLLS for a range of kinetic parameters. The whole-field LLS method allowed generating liver perfusion maps approximately 160-fold faster than voxel-wise NLLS, while obtaining similar perfusion parameters. Delay-compensated dual-input liver perfusion analysis using whole-field LLS allows generating perfusion maps with a considerable speedup compared with conventional voxel-wise NLLS fitting. Magn Reson Med 79:2415-2421, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Hall versus conventional stainless steel crown techniques: in vitro investigation of marginal fit and microleakage using three different luting agents.

PubMed

Erdemci, Zeynep Yalçınkaya; Cehreli, S Burçak; Tirali, R Ebru

2014-01-01

This study's purpose was to investigate microleakage and marginal discrepancies in stainless steel crowns (SSCs) placed using conventional and Hall techniques and cemented with three different luting agents. Seventy-eight human primary maxillary second molars were randomly assigned to two groups (N=39), and SSCs were applied either with the Hall or conventional technique. These two groups were further subgrouped according to the material used for crown cementation (N=13 per group). Two specimens in each group were processed for scanning electron microscopy investigation. The extent of microleakage and marginal fit was quantified in millimeters on digitally photographed sections using image analysis software. The data were compared with a two-way independent and a two-way mixed analysis of variance (P=.05). The scores in the Hall group were significantly worse than those in the conventional technique group (P<.05). In both groups, resin cement displayed the lowest extent of microleakage, followed by glass ionomer and polycarboxylate cements (P<.05). Stainless steel crowns applied using the Hall technique displayed higher microleakage scores than those applied using the conventional technique, regardless of the cementation material. When the interaction of the material and technique was assessed, resin cement presented as the best choice for minimizing microleakage in both techniques.

Accuracy of ringless casting and accelerated wax-elimination technique: a comparative in vitro study.

PubMed

Prasad, Rahul; Al-Keraif, Abdulaziz Abdullah; Kathuria, Nidhi; Gandhi, P V; Bhide, S V

2014-02-01

The purpose of this study was to determine whether the ringless casting and accelerated wax-elimination techniques can be combined to offer a cost-effective, clinically acceptable, and time-saving alternative for fabricating single unit castings in fixed prosthodontics. Sixty standardized wax copings were fabricated on a type IV stone replica of a stainless steel die. The wax patterns were divided into four groups. The first group was cast using the ringless investment technique and conventional wax-elimination method; the second group was cast using the ringless investment technique and accelerated wax-elimination method; the third group was cast using the conventional metal ring investment technique and conventional wax-elimination method; the fourth group was cast using the metal ring investment technique and accelerated wax-elimination method. The vertical marginal gap was measured at four sites per specimen, using a digital optical microscope at 100× magnification. The results were analyzed using two-way ANOVA to determine statistical significance. The vertical marginal gaps of castings fabricated using the ringless technique (76.98 ± 7.59 μm) were significantly less (p < 0.05) than those castings fabricated using the conventional metal ring technique (138.44 ± 28.59 μm); however, the vertical marginal gaps of the conventional (102.63 ± 36.12 μm) and accelerated wax-elimination (112.79 ± 38.34 μm) castings were not statistically significant (p > 0.05). The ringless investment technique can produce castings with higher accuracy and can be favorably combined with the accelerated wax-elimination method as a vital alternative to the time-consuming conventional technique of casting restorations in fixed prosthodontics. © 2013 by the American College of Prosthodontists.

Development of a Neutron Diffraction Based Experiemental Capability for Investigating Hydraulic Fracturing for EGS-like Conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Polsky, Yarom; Anovitz, Lawrence; An, Ke

2013-01-01

Hydraulic fracturing to enhance formation permeability is an established practice in the Oil & Gas (O&G) industry and is expected to be an enabler for EGS. However, it is rarely employed in conventional geothermal systems and there are significant questions regarding the translation of practice from O&G to both conventional geothermal and EGS applications. Lithological differences(sedimentary versus crystalline rocks, significantly greater formation temperatures and different desired fracture characteristics are among a number of factors that are likely to result in a gap of understanding of how to manage hydraulic fracturing practice for geothermal. Whereas the O&G community has had bothmore » the capital and the opportunity to develop its understanding of hydraulic fracturing operations empirically in the field as well through extensive R&D efforts, field testing opportunities for EGS are likely to be minimal due to the high expense of hydraulic fracturing field trials. A significant portion of the knowledge needed to guide the management of geothermal/EGS hydraulic fracturing operations will therefore likely have to come from experimental efforts and simulation. This paper describes ongoing efforts at Oak Ridge National Laboratory (ORNL) to develop an experimental capability to map the internal stresses/strains in core samples subjected to triaxial stress states and temperatures representative of EGS-like conditions using neutron diffraction based strain mapping techniques. This capability is being developed at ORNL\\'s Spallation Neutron Source, the world\\'s most powerful pulsed neutron source and is still in a proof of concept phase. A specialized pressure cell has been developed that permits independent radial and axial fluid pressurization of core samples, with axial flow through capability and a temperature rating up to 300 degrees C. This cell will ultimately be used to hydraulically pressurize EGS-representative core samples to conditions of imminent fracture and map the associated internal strain states of the sample. This will hopefully enable a more precise mapping of the rock material failure envelope, facilitate a more refined understanding of the mechanism of hydraulically induced rock fracture, particularly in crystalline rocks, and serve as a platform for validating and improving fracture simulation codes. The elements of the research program and preliminary strain mapping results of a Sierra White granite sample subjected only to compressive loading will be discussed in this paper.« less

Ultrasound elastography of the prostate: state of the art.

PubMed

Correas, J-M; Tissier, A-M; Khairoune, A; Khoury, G; Eiss, D; Hélénon, O

2013-05-01

Prostate cancer is the cancer exhibiting the highest incidence rate and it appears as the second cause of cancer death in men, after lung cancer. Prostate cancer is difficult to detect, and the treatment efficacy remains limited despite the increase use of biological tests (prostate-specific antigen [PSA] dosage), the development of new imaging modalities, and the use of invasive procedures such as biopsy. Ultrasound elastography is a novel imaging technique capable of mapping tissue stiffness of the prostate. It is known that prostatic cancer tissue is often harder than healthy tissue (information used by digital rectal examination [DRE]). Two elastography techniques have been developed based on different principles: first, quasi-static (or strain) technique, and second, shear wave technique. The tissue stiffness information provided by US elastography should improve the detection of prostate cancer and provide guidance for biopsy. Prostate elastography provides high sensitivity for detecting prostate cancer and shows high negative predictive values, ensuring that few cancers will be missed. US elastography should become an additional method of imaging the prostate, complementing the conventional transrectal ultrasound and MRI. This technique requires significant training (especially for quasi-static elastography) to become familiar with acquisition process, acquisition technique, characteristics and limitations, and to achieve correct diagnoses. Copyright © 2013 Éditions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

A spectroscopic search for faint secondaries in cataclysmic variables

NASA Astrophysics Data System (ADS)

Vande Putte, D.; Smith, Robert Connon; Hawkins, N. A.; Martin, J. S.

2003-06-01

The secondary in cataclysmic variables (CVs) is usually detected by cross-correlation of the CV spectrum with that of a K or M dwarf template, to produce a radial velocity curve. Although this method has demonstrated its power, it has its limits in the case of noisy spectra, such as are found when the secondary is faint. A method of coadding spectra, called skew mapping, has been proposed in the past. Gradually, examples of its application are being published; none the less, so far no journal article has described the technique in detail. To answer this need, this paper explores in detail the capabilities of skew mapping when determining the amplitude of the radial velocity for faint secondaries. It demonstrates the power of the method over techniques that are more conventional, when the signal-to-noise ratio is poor. The paper suggests an approach to assessing the quality of results. This leads in the case of the investigated objects to a first tier of results, where we find K2= 127 +/- 23 km s-1 for SY Cnc, K2= 144 +/- 18 km s-1 for RW Sex and K2= 262 +/- 14 km s-1 for UX UMa. These we believe to be the first direct determinations of K2 for these objects. Furthermore, we also obtain K2= 263 +/- 30 km s-1 for RW Tri, close to a skew mapping result obtained elsewhere. In the first three cases, we use these results to derive the mass of the white dwarf companion. A second tier of results includes UU Aqr, EX Hya and LX Ser, for which we propose more tentative values of K2. Clear failures of the method are also discussed (EF Eri, VV Pup and SW Sex).

The AAPM/RSNA physics tutorial for residents: digital fluoroscopy.

PubMed

Pooley, R A; McKinney, J M; Miller, D A

2001-01-01

A digital fluoroscopy system is most commonly configured as a conventional fluoroscopy system (tube, table, image intensifier, video system) in which the analog video signal is converted to and stored as digital data. Other methods of acquiring the digital data (eg, digital or charge-coupled device video and flat-panel detectors) will become more prevalent in the future. Fundamental concepts related to digital imaging in general include binary numbers, pixels, and gray levels. Digital image data allow the convenient use of several image processing techniques including last image hold, gray-scale processing, temporal frame averaging, and edge enhancement. Real-time subtraction of digital fluoroscopic images after injection of contrast material has led to widespread use of digital subtraction angiography (DSA). Additional image processing techniques used with DSA include road mapping, image fade, mask pixel shift, frame summation, and vessel size measurement. Peripheral angiography performed with an automatic moving table allows imaging of the peripheral vasculature with a single contrast material injection.

Complex wavefront sensing with a plenoptic sensor

NASA Astrophysics Data System (ADS)

Wu, Chensheng; Ko, Jonathan; Davis, Christopher C.

2016-09-01

There are many techniques to achieve basic wavefront sensing tasks in the weak atmospheric turbulence regime. However, in strong and deep turbulence situations, the complexity of a propagating wavefront increases significantly. Typically, beam breakup will happen and various portions of the beam will randomly interfere with each other. Consequently, some conventional techniques for wavefront sensing turn out to be inaccurate and misleading. For example, a Shack-Hartmann sensor will be confused by multi-spot/zero-spot result in some cells. The curvature sensor will be affected by random interference patterns for both the image acquired before the focal plane and the image acquired after the focal plane. We propose the use of a plenoptic sensor to solve complex wavefront sensing problems. In fact, our results show that even for multiple beams (their wavelengths can be the same) passing through the same turbulent channel, the plenoptic sensor can reconstruct the turbulence-induced distortion accurately. In this paper, we will demonstrate the plenoptic mapping principle to analyze and reconstruct the complex wavefront of a distorted laser beam.

An analytical method to simulate the H I 21-cm visibility signal for intensity mapping experiments

NASA Astrophysics Data System (ADS)

Sarkar, Anjan Kumar; Bharadwaj, Somnath; Marthi, Visweshwar Ram

2018-01-01

Simulations play a vital role in testing and validating H I 21-cm power spectrum estimation techniques. Conventional methods use techniques like N-body simulations to simulate the sky signal which is then passed through a model of the instrument. This makes it necessary to simulate the H I distribution in a large cosmological volume, and incorporate both the light-cone effect and the telescope's chromatic response. The computational requirements may be particularly large if one wishes to simulate many realizations of the signal. In this paper, we present an analytical method to simulate the H I visibility signal. This is particularly efficient if one wishes to simulate a large number of realizations of the signal. Our method is based on theoretical predictions of the visibility correlation which incorporate both the light-cone effect and the telescope's chromatic response. We have demonstrated this method by applying it to simulate the H I visibility signal for the upcoming Ooty Wide Field Array Phase I.

Cell force mapping using a double-sided micropillar array based on the moiré fringe method

NASA Astrophysics Data System (ADS)

Zhang, F.; Anderson, S.; Zheng, X.; Roberts, E.; Qiu, Y.; Liao, R.; Zhang, X.

2014-07-01

The mapping of traction forces is crucial to understanding the means by which cells regulate their behavior and physiological function to adapt to and communicate with their local microenvironment. To this end, polymeric micropillar arrays have been used for measuring cell traction force. However, the small scale of the micropillar deflections induced by cell traction forces results in highly inefficient force analyses using conventional optical approaches; in many cases, cell forces may be below the limits of detection achieved using conventional microscopy. To address these limitations, the moiré phenomenon has been leveraged as a visualization tool for cell force mapping due to its inherent magnification effect and capacity for whole-field force measurements. This Letter reports an optomechanical cell force sensor, namely, a double-sided micropillar array (DMPA) made of poly(dimethylsiloxane), on which one side is employed to support cultured living cells while the opposing side serves as a reference pattern for generating moiré patterns. The distance between the two sides, which is a crucial parameter influencing moiré pattern contrast, is predetermined during fabrication using theoretical calculations based on the Talbot effect that aim to optimize contrast. Herein, double-sided micropillar arrays were validated by mapping mouse embryo fibroblast contraction forces and the resulting force maps compared to conventional microscopy image analyses as the reference standard. The DMPA-based approach precludes the requirement for aligning two independent periodic substrates, improves moiré contrast, and enables efficient moiré pattern generation. Furthermore, the double-sided structure readily allows for the integration of moiré-based cell force mapping into microfabricated cell culture environments or lab-on-a-chip devices.

Atrial Fibrillation Ablation Guided by a Novel Nonfluoroscopic Navigation System.

PubMed

Ballesteros, Gabriel; Ramos, Pablo; Neglia, Renzo; Menéndez, Diego; García-Bolao, Ignacio

2017-09-01

Rhythmia is a new nonfluoroscopic navigation system that is able to create high-density electroanatomic maps. The aim of this study was to describe the acute outcomes of atrial fibrillation (AF) ablation guided by this system, to analyze the volume provided by its electroanatomic map, and to describe its ability to locate pulmonary vein (PV) reconnection gaps in redo procedures. This observational study included 62 patients who underwent AF ablation with Rhythmia compared with a retrospective cohort who underwent AF ablation with a conventional nonfluoroscopic navigation system (Ensite Velocity). The number of surface electrograms per map was significantly higher in Rhythmia procedures (12 125 ± 2826 vs 133 ± 21 with Velocity; P < .001), with no significant differences in the total procedure time. The Orion catheter was placed for mapping in 99.5% of PV (95.61% in the control group with a conventional circular mapping catheter; P = .04). There were no significant differences in the percentage of PV isolation between the 2 groups. In redo procedures, an ablation gap could be identified on the activation map in 67% of the reconnected PV (40% in the control group; P = .042). The measured left atrial volume was lower than that calculated by computed tomography (109.3 v 15.2 and 129.9 ± 13.2 mL, respectively; P < .001). There were no significant differences in the number of complications. The Rhythmia system is effective for AF ablation procedures, with procedure times and safety profiles similar to conventional nonfluoroscopic navigation systems. In redo procedures, it appears to be more effective in identifying reconnected PV conduction gaps. Copyright © 2016 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

User Preferences in Image Map Using

NASA Astrophysics Data System (ADS)

Vondráková, A.; Vozenilek, V.

2016-06-01

In the process of map making, the attention is given to the resulting image map (to be accurate, readable, and suit the primary purpose) and its user aspects. Current cartography understands the user issues as all matters relating to user perception, map use and also user preferences. Most commercial cartographic production is strongly connected to economic circumstances. Companies are discovering user's interests and market demands. However, is it sufficient to focus just on the user's preferences? Recent research on user aspects at Palacký University Olomouc addresses a much wider scope of user aspects. The user's preferences are very often distorting - the users think that the particular image map is kind, beautiful, and useful and they wants to buy it (or use it - it depends on the form of the map production). But when the same user gets the task to use practically this particular map (such as finding the shortest way), so the user concludes that initially preferred map is useless, and uses a map, that was worse evaluated according to his preferences. It is, therefore, necessary to evaluate not only the correctness of image maps and their aesthetics but also to assess the user perception and other user issues. For the accomplishment of such testing, eye-tracking technology is a useful tool. The research analysed how users read image maps, or if they prefer image maps over traditional maps. The eye tracking experiment on the comparison of the conventional and image map reading was conducted. The map readers were asked to solve few simple tasks with either conventional or image map. The readers' choice of the map to solve the task was one of investigated aspect of user preferences. Results demonstrate that the user preferences and user needs are often quite different issues. The research outcomes show that it is crucial to implement map user testing into the cartographic production process.

A Method of Surrogate Model Construction which Leverages Lower-Fidelity Information using Space Mapping Techniques

DTIC Science & Technology

2014-03-27

fidelity. This pairing is accomplished through the use of a space mapping technique, which is a process where the design space of a lower fidelity model...is aligned a higher fidelity model. The intent of applying space mapping techniques to the field of surrogate construction is to leverage the

Mapping 180° polar domains using electron backscatter diffraction and dynamical scattering simulations

DOE PAGES

Burch, Matthew J.; Fancher, Chris M.; Patala, Srikanth; ...

2016-11-18

A novel technique, which directly and nondestructively maps polar domains using electron backscatter diffraction (EBSD) is described and demonstrated. Through dynamical diffraction simulations and quantitative comparison to experimental EBSD patterns, the absolute orientation of a non-centrosymmetric crystal can be determined. With this information, the polar domains of a material can be mapped. The technique is demonstrated by mapping the non-ferroelastic, or 180°, ferroelectric domains in periodically poled LiNbO 3 single crystals. Furthermore, the authors demonstrate the possibility of mapping polarity using this technique in other polar materials system.

[The anesthetic effects of Gow-Gates technique of inferior alveolar nerve block in impacted mandibular third molar extraction].

PubMed

Yang, Jieping; Liu, Wei; Gao, Qinghong

2013-08-01

To evaluate the anesthetic effects and safety of Gow-Gates technique of inferior alveolar nerve block in impacted mandibular third molar extraction. A split-mouth study was designed. The bilateral impacted mandibular third molar of 32 participants were divided into Gow-Gates technique of inferior alveolar nerve block (Gow-Gates group) and conventional technique of inferior alveolar nerve block (conventional group) randomly with third molar extracted. The anesthetic effects and adverse events were recorded. All the participants completed the research. The anesthetic success rate was 96.9% in Gow-Gates group and 90.6% in conventional group with no statistical difference ( P= 0.317); but when comparing the anesthesia grade, Gow-Gates group had a 96.9% of grade A and B, and conventional group had a rate of 78.1% (P = 0.034). And the Gow-Gates group had a much lower withdrawn bleeding than conventional group (P = 0.025). Two groups had no hematoma. Gow-Gates technique had a reliable anesthesia effects and safety in impacted mandibular third molar extraction and could be chosen as a candidate for the conventional inferior alveolar nerve block.

Evaluation of ERTS-1 imagery for spectral geological mapping in diverse terranes of New York State

NASA Technical Reports Server (NTRS)

Isachsen, Y. W. (Principal Investigator); Fakundiny, R. H.; Forster, S. W.

1973-01-01

The author has identified the following significant results. Linear anomalies dominate the new geological information derived from ERTS-1 imagery, total lengths now exceeding 6000 km. Experimentation with a variety of viewing techniques suggest that conventional photogeologic analyses of band 7 results in the location of more than 97 percent of all linears found. Bedrock lithologic types are distinguishable only where they are topographically expressed or govern land use signatures. The maxima on rose diagrams for ERTS-1 anomalies correspond well with those for mapped faults and topographic lineaments. A multiscale analysis of linears showed that single topographic linears at 1:2,500,000 became dashed linears at 1:1,000,000 aligned zones of shorter parallel, en echelon, or conjugate linears at 1:500,00. Most circular features found were explained away by U-2 airphoto analysis but several remain as anomalies. Visible glacial features include individual drumlins, best seen in winter imagery, drumlinoids, eskers, ice-marginal drainage channels, glacial lake shorelines and sand plains, and end moraines.

Utility of Satellite Magnetic Observations for Estimating Near-Surface Magnetic Anomalies

NASA Technical Reports Server (NTRS)

Kim, Hyung Rae; vonFrese, Ralph R. B.; Taylor, Patrick T.; Kim, Jeong Woo; Park, Chan Hong

2003-01-01

Regional to continental scale magnetic anomaly maps are becoming increasingly available from airborne, shipborne, and terrestrial surveys. Satellite data are commonly considered to fill the coverage gaps in regional compilations of these near-surface surveys. For the near-surface Antarctic magnetic anomaly map being produced by the Antarctic Digital Magnetic Anomaly Project (ADMAP), we show that near-surface magnetic anomaly estimation is greatly enhanced by the joint inversion of the near-surface data with the satellite observations relative to the conventional technique such as minimum curvature. Orsted observations are especially advantageous relative to the Magsat data that have order-of-magnitude greater measurement errors, albeit at much lower orbital altitudes. CHAMP is observing the geomagnetic field with the same measurement accuracy as the Orsted mission, but at the lower orbital altitudes covered by Magsat. Hence, additional significant improvement in predicting near-surface magnetic anomalies can result as these CHAMP data are available. Our analysis also suggests that considerable new insights on the magnetic properties of the lithosphere may be revealed by a further order-of-magnitude improvement in the accuracy of the magnetometer measurements at minimum orbital altitude.

Late diagenetic indicators of buried oil and gas: II, Direct detection experiment at Cement and Garza oil fields, Oklahoma and Texas, using enhanced LANDSAT I and II images

USGS Publications Warehouse

Donovan, Terrence J.; Termain, Patricia A.; Henry, Mitchell E.

1979-01-01

The Cement oil field, Oklahoma, was a test site for an experiment designed to evaluate LANDSAT's capability to detect an alteration zone in surface rocks caused by hydrocarbon microseepage. Loss of iron and impregnation of sandstone by carbonate cements and replacement of gypsum by calcite are the major alteration phenomena at Cement. The bedrock alterations are partially masked by unaltered overlying beds, thick soils, and dense natural and cultivated vegetation. Interpreters biased by detailed ground truth were able to map the alteration zone subjectively using a magnified, filtered, and sinusoidally stretched LANDSAT composite image; other interpreters, unbiased by ground truth data, could not duplicate that interpretation. Similar techniques were applied at a secondary test site (Garza oil field, Texas), where similar alterations in surface rocks occur. Enhanced LANDSAT images resolved the alteration zone to a biased interpreter and some individual altered outcrops could be mapped using higher resolution SKYLAB color and conventional black and white aerial photographs suggesting repeat experiments with LANDSAT C and D.

Enhancing in vivo tumor boundary delineation with structured illumination fluorescence molecular imaging and spatial gradient mapping

NASA Astrophysics Data System (ADS)

Sun, Jessica; Miller, Jessica P.; Hathi, Deep; Zhou, Haiying; Achilefu, Samuel; Shokeen, Monica; Akers, Walter J.

2016-08-01

Fluorescence imaging, in combination with tumor-avid near-infrared (NIR) fluorescent molecular probes, provides high specificity and sensitivity for cancer detection in preclinical animal models, and more recently, assistance during oncologic surgery. However, conventional camera-based fluorescence imaging techniques are heavily surface-weighted such that surface reflection from skin or other nontumor tissue and nonspecific fluorescence signals dominate, obscuring true cancer-specific signals and blurring tumor boundaries. To address this challenge, we applied structured illumination fluorescence molecular imaging (SIFMI) in live animals for automated subtraction of nonspecific surface signals to better delineate accumulation of an NIR fluorescent probe targeting α4β1 integrin in mice bearing subcutaneous plasma cell xenografts. SIFMI demonstrated a fivefold improvement in tumor-to-background contrast when compared with other full-field fluorescence imaging methods and required significantly reduced scanning time compared with diffuse optical spectroscopy imaging. Furthermore, the spatial gradient mapping enhanced highlighting of tumor boundaries. Through the relatively simple hardware and software modifications described, SIFMI can be integrated with clinical fluorescence imaging systems, enhancing intraoperative tumor boundary delineation from the uninvolved tissue.

Distribution and visualisation of chlorhexidine within the skin using ToF-SIMS: a potential platform for the design of more efficacious skin antiseptic formulations.

PubMed

Judd, Amy M; Scurr, David J; Heylings, Jon R; Wan, Ka-Wai; Moss, Gary P

2013-07-01

In order to increase the efficacy of a topically applied antimicrobial compound the permeation profile, localisation and mechanism of action within the skin must first be investigated. Time-of-flight secondary ion mass spectrometry (ToF-SIMS) was used to visualise the distribution of a conventional antimicrobial compound, chlorhexidine digluconate, within porcine skin without the need for laborious preparation, radio-labels or fluorescent tags. High mass resolution and high spatial resolution mass spectra and chemical images were achieved when analysing chlorhexidine digluconate treated cryo-sectioned porcine skin sections by ToF-SIMS. The distribution of chlorhexidine digluconate was mapped throughout the skin sections and our studies indicate that the compound appears to be localised within the stratum corneum. In parallel, tape strips taken from chlorhexidine digluconate treated porcine skin were analysed by ToF-SIMS to support the distribution profile obtained from the skin sections. ToF-SIMS can act as a powerful complementary technique to map the distribution of topically applied compounds within the skin.

Poster - 52: Smoothing constraints in Modulated Photon Radiotherapy (XMRT) fluence map optimization

DOE Office of Scientific and Technical Information (OSTI.GOV)

McGeachy, Philip; Villarreal-Barajas, Jose Eduardo

Purpose: Modulated Photon Radiotherapy (XMRT), which simultaneously optimizes photon beamlet energy (6 and 18 MV) and fluence, has recently shown dosimetric improvement in comparison to conventional IMRT. That said, the degree of smoothness of resulting fluence maps (FMs) has yet to be investigated and could impact the deliverability of XMRT. This study looks at investigating FM smoothness and imposing smoothing constraint in the fluence map optimization. Methods: Smoothing constraints were modeled in the XMRT algorithm with the sum of positive gradient (SPG) technique. XMRT solutions, with and without SPG constraints, were generated for a clinical prostate scan using standard dosimetricmore » prescriptions, constraints, and a seven coplanar beam arrangement. The smoothness, with and without SPG constraints, was assessed by looking at the absolute and relative maximum SPG scores for each fluence map. Dose volume histograms were utilized when evaluating impact on the dose distribution. Results: Imposing SPG constraints reduced the absolute and relative maximum SPG values by factors of up to 5 and 2, respectively, when compared with their non-SPG constrained counterparts. This leads to a more seamless conversion of FMS to their respective MLC sequences. This improved smoothness resulted in an increase to organ at risk (OAR) dose, however the increase is not clinically significant. Conclusions: For a clinical prostate case, there was a noticeable improvement in the smoothness of the XMRT FMs when SPG constraints were applied with a minor increase in dose to OARs. This increase in OAR dose is not clinically meaningful.« less

Fast flow-based algorithm for creating density-equalizing map projections

PubMed Central

Gastner, Michael T.; Seguy, Vivien; More, Pratyush

2018-01-01

Cartograms are maps that rescale geographic regions (e.g., countries, districts) such that their areas are proportional to quantitative demographic data (e.g., population size, gross domestic product). Unlike conventional bar or pie charts, cartograms can represent correctly which regions share common borders, resulting in insightful visualizations that can be the basis for further spatial statistical analysis. Computer programs can assist data scientists in preparing cartograms, but developing an algorithm that can quickly transform every coordinate on the map (including points that are not exactly on a border) while generating recognizable images has remained a challenge. Methods that translate the cartographic deformations into physics-inspired equations of motion have become popular, but solving these equations with sufficient accuracy can still take several minutes on current hardware. Here we introduce a flow-based algorithm whose equations of motion are numerically easier to solve compared with previous methods. The equations allow straightforward parallelization so that the calculation takes only a few seconds even for complex and detailed input. Despite the speedup, the proposed algorithm still keeps the advantages of previous techniques: With comparable quantitative measures of shape distortion, it accurately scales all areas, correctly fits the regions together, and generates a map projection for every point. We demonstrate the use of our algorithm with applications to the 2016 US election results, the gross domestic products of Indian states and Chinese provinces, and the spatial distribution of deaths in the London borough of Kensington and Chelsea between 2011 and 2014. PMID:29463721

Kite aerial photography for low-cost, ultra-high spatial resolution multi-spectral mapping of intertidal landscapes.

PubMed

Bryson, Mitch; Johnson-Roberson, Matthew; Murphy, Richard J; Bongiorno, Daniel

2013-01-01

Intertidal ecosystems have primarily been studied using field-based sampling; remote sensing offers the ability to collect data over large areas in a snapshot of time that could complement field-based sampling methods by extrapolating them into the wider spatial and temporal context. Conventional remote sensing tools (such as satellite and aircraft imaging) provide data at limited spatial and temporal resolutions and relatively high costs for small-scale environmental science and ecologically-focussed studies. In this paper, we describe a low-cost, kite-based imaging system and photogrammetric/mapping procedure that was developed for constructing high-resolution, three-dimensional, multi-spectral terrain models of intertidal rocky shores. The processing procedure uses automatic image feature detection and matching, structure-from-motion and photo-textured terrain surface reconstruction algorithms that require minimal human input and only a small number of ground control points and allow the use of cheap, consumer-grade digital cameras. The resulting maps combine imagery at visible and near-infrared wavelengths and topographic information at sub-centimeter resolutions over an intertidal shoreline 200 m long, thus enabling spatial properties of the intertidal environment to be determined across a hierarchy of spatial scales. Results of the system are presented for an intertidal rocky shore at Jervis Bay, New South Wales, Australia. Potential uses of this technique include mapping of plant (micro- and macro-algae) and animal (e.g. gastropods) assemblages at multiple spatial and temporal scales.

Ablation of post-surgical intra-atrial reentrant tachycardia. Predilection target sites and mapping approach.

PubMed

Anné, W; van Rensburg, H; Adams, J; Ector, H; Van de Werf, F; Heidbüchel, H

2002-10-01

Atrial arrhythmias are a frequent complication of atrial surgery. The location of these tachycardias is very diverse due to the individual difference in the original anatomy, surgical corrections, and effects of atrial fibrosis. Nevertheless some recurrent patterns are emerging. Forty-five patients underwent 51 ablation procedures between September 1995 and March 2001 using conventional mapping and temperature-controlled ablation. A duadecapolar catheter was swept from anterior to posterior in the right (and/or left) atrium, allowing for rapid mapping followed by entrainment confirmation. Twenty-eight patients had corrected congenital heart disease, 17 surgery for acquired heart disease. One hundred and sixteen arrhythmias were found, 86 circuits were targeted, 81 with success (94%). Despite the heterogeneous anatomy, the same targets were often encountered: the posterior isthmus between the inferior vena cava and the tricuspid ring (62%), the gap between the inferior vena cava and the atriotomy scar (49%), and the region around the atriopulmonary connection in Fontans (two out of four patients). After a mean follow-up of 24 months, 13 patients had a recurrent arrhythmia (29%) after their last procedure. There was a significant association between the number of circuits found during the initial procedure and the likelihood of recurrent arrhythmias. Knowledge of anatomical predilection sites and mapping the right (and/or left) atrium with a 'sweeping Halo technique' allow for effective ablation of most post-surgical atrial tachycardias. Severely damaged atria with multiple arrhythmias may require 'preventive' ablation of all recognizable channels.

Kite Aerial Photography for Low-Cost, Ultra-high Spatial Resolution Multi-Spectral Mapping of Intertidal Landscapes

PubMed Central

Bryson, Mitch; Johnson-Roberson, Matthew; Murphy, Richard J.; Bongiorno, Daniel

2013-01-01

Intertidal ecosystems have primarily been studied using field-based sampling; remote sensing offers the ability to collect data over large areas in a snapshot of time that could complement field-based sampling methods by extrapolating them into the wider spatial and temporal context. Conventional remote sensing tools (such as satellite and aircraft imaging) provide data at limited spatial and temporal resolutions and relatively high costs for small-scale environmental science and ecologically-focussed studies. In this paper, we describe a low-cost, kite-based imaging system and photogrammetric/mapping procedure that was developed for constructing high-resolution, three-dimensional, multi-spectral terrain models of intertidal rocky shores. The processing procedure uses automatic image feature detection and matching, structure-from-motion and photo-textured terrain surface reconstruction algorithms that require minimal human input and only a small number of ground control points and allow the use of cheap, consumer-grade digital cameras. The resulting maps combine imagery at visible and near-infrared wavelengths and topographic information at sub-centimeter resolutions over an intertidal shoreline 200 m long, thus enabling spatial properties of the intertidal environment to be determined across a hierarchy of spatial scales. Results of the system are presented for an intertidal rocky shore at Jervis Bay, New South Wales, Australia. Potential uses of this technique include mapping of plant (micro- and macro-algae) and animal (e.g. gastropods) assemblages at multiple spatial and temporal scales. PMID:24069206

Two techniques for mapping and area estimation of small grains in California using Landsat digital data

NASA Technical Reports Server (NTRS)

Sheffner, E. J.; Hlavka, C. A.; Bauer, E. M.

1984-01-01

Two techniques have been developed for the mapping and area estimation of small grains in California from Landsat digital data. The two techniques are Band Ratio Thresholding, a semi-automated version of a manual procedure, and LCLS, a layered classification technique which can be fully automated and is based on established clustering and classification technology. Preliminary evaluation results indicate that the two techniques have potential for providing map products which can be incorporated into existing inventory procedures and automated alternatives to traditional inventory techniques and those which currently employ Landsat imagery.

Conventional and conformal technique of external beam radiotherapy in locally advanced cervical cancer: Dose distribution, tumor response, and side effects

NASA Astrophysics Data System (ADS)

Mutrikah, N.; Winarno, H.; Amalia, T.; Djakaria, M.

2017-08-01

The objective of this study was to compare conventional and conformal techniques of external beam radiotherapy (EBRT) in terms of the dose distribution, tumor response, and side effects in the treatment of locally advanced cervical cancer patients. A retrospective cohort study was conducted on cervical cancer patients who underwent EBRT before brachytherapy in the Radiotherapy Department of Cipto Mangunkusumo Hospital. The prescribed dose distribution, tumor response, and acute side effects of EBRT using conventional and conformal techniques were investigated. In total, 51 patients who underwent EBRT using conventional techniques (25 cases using Cobalt-60 and 26 cases using a linear accelerator (LINAC)) and 29 patients who underwent EBRT using conformal techniques were included in the study. The distribution of the prescribed dose in the target had an impact on the patient’s final response to EBRT. The complete response rate of patients to conformal techniques was significantly greater (58%) than that of patients to conventional techniques (42%). No severe acute local side effects were seen in any of the patients (Radiation Therapy Oncology Group (RTOG) grades 3-4). The distribution of the dose and volume to the gastrointestinal tract affected the proportion of mild acute side effects (RTOG grades 1-2). The urinary bladder was significantly greater using conventional techniques (Cobalt-60/LINAC) than using conformal techniques at 72% and 78% compared to 28% and 22%, respectively. The use of conformal techniques in pelvic radiation therapy is suggested in radiotherapy centers with CT simulators and 3D Radiotherapy Treatment Planning Systems (RTPSs) to decrease some uncertainties in radiotherapy planning. The use of AP/PA pelvic radiation techniques with Cobalt-60 should be limited in body thicknesses equal to or less than 18 cm. When using conformal techniques, delineation should be applied in the small bowel, as it is considered a critical organ according to RTOG consensus guidelines.

Quantifying Patterns of Smooth Muscle Motility in the Gut and Other Organs With New Techniques of Video Spatiotemporal Mapping

PubMed Central

Lentle, Roger G.; Hulls, Corrin M.

2018-01-01

The uses and limitations of the various techniques of video spatiotemporal mapping based on change in diameter (D-type ST maps), change in longitudinal strain rate (L-type ST maps), change in area strain rate (A-type ST maps), and change in luminous intensity of reflected light (I-maps) are described, along with their use in quantifying motility of the wall of hollow structures of smooth muscle such as the gut. Hence ST-methods for determining the size, speed of propagation and frequency of contraction in the wall of gut compartments of differing geometric configurations are discussed. We also discuss the shortcomings and problems that are inherent in the various methods and the use of techniques to avoid or minimize them. This discussion includes, the inability of D-type ST maps to indicate the site of a contraction that does not reduce the diameter of a gut segment, the manipulation of axis [the line of interest (LOI)] of L-maps to determine the true axis of propagation of a contraction, problems with anterior curvature of gut segments and the use of adjunct image analysis techniques that enhance particular features of the maps. PMID:29686624

Marginal and internal fit of cobalt-chromium copings fabricated using the conventional and the direct metal laser sintering techniques: A comparative in vitro study.

PubMed

Ullattuthodi, Sujana; Cherian, Kandathil Phillip; Anandkumar, R; Nambiar, M Sreedevi

2017-01-01

This in vitro study seeks to evaluate and compare the marginal and internal fit of cobalt-chromium copings fabricated using the conventional and direct metal laser sintering (DMLS) techniques. A master model of a prepared molar tooth was made using cobalt-chromium alloy. Silicone impression of the master model was made and thirty standardized working models were then produced; twenty working models for conventional lost-wax technique and ten working models for DMLS technique. A total of twenty metal copings were fabricated using two different production techniques: conventional lost-wax method and DMLS; ten samples in each group. The conventional and DMLS copings were cemented to the working models using glass ionomer cement. Marginal gap of the copings were measured at predetermined four points. The die with the cemented copings are standardized-sectioned with a heavy duty lathe. Then, each sectioned samples were analyzed for the internal gap between the die and the metal coping using a metallurgical microscope. Digital photographs were taken at ×50 magnification and analyzed using measurement software. Statistical analysis was done by unpaired t -test and analysis of variance (ANOVA). The results of this study reveal that no significant difference was present in the marginal gap of conventional and DMLS copings ( P > 0.05) by means of ANOVA. The mean values of internal gap of DMLS copings were significantly greater than that of conventional copings ( P < 0.05). Within the limitations of this in vitro study, it was concluded that the internal fit of conventional copings was superior to that of the DMLS copings. Marginal fit of the copings fabricated by two different techniques had no significant difference.

Digital Mapping Techniques '08—Workshop Proceedings, Moscow, Idaho, May 18–21, 2008

USGS Publications Warehouse

Soller, David R.

2009-01-01

The Digital Mapping Techniques '08 (DMT'08) workshop was attended by more than 100 technical experts from 40 agencies, universities, and private companies, including representatives from 24 State geological surveys. This year's meeting, the twelfth in the annual series, was hosted by the Idaho Geological Survey, from May 18-21, 2008, on the University of Idaho campus in Moscow, Idaho. Each DMT workshop has been coordinated by the U.S. Geological Survey's National Geologic Map Database Project and the Association of American State Geologists (AASG). As in previous years' meetings, the objective was to foster informal discussion and exchange of technical information, principally in order to develop more efficient methods for digital mapping, cartography, GIS analysis, and information management. At this meeting, oral and poster presentations and special discussion sessions emphasized (1) methods for creating and publishing map products (here, "publishing" includes Web-based release); (2) field data capture software and techniques, including the use of LiDAR; (3) digital cartographic techniques; (4) migration of digital maps into ArcGIS Geodatabase format; (5) analytical GIS techniques; and (6) continued development of the National Geologic Map Database.

Virtual 3d City Modeling: Techniques and Applications

NASA Astrophysics Data System (ADS)

Singh, S. P.; Jain, K.; Mandla, V. R.

2013-08-01

3D city model is a digital representation of the Earth's surface and it's related objects such as Building, Tree, Vegetation, and some manmade feature belonging to urban area. There are various terms used for 3D city models such as "Cybertown", "Cybercity", "Virtual City", or "Digital City". 3D city models are basically a computerized or digital model of a city contains the graphic representation of buildings and other objects in 2.5 or 3D. Generally three main Geomatics approach are using for Virtual 3-D City models generation, in first approach, researcher are using Conventional techniques such as Vector Map data, DEM, Aerial images, second approach are based on High resolution satellite images with LASER scanning, In third method, many researcher are using Terrestrial images by using Close Range Photogrammetry with DSM & Texture mapping. We start this paper from the introduction of various Geomatics techniques for 3D City modeling. These techniques divided in to two main categories: one is based on Automation (Automatic, Semi-automatic and Manual methods), and another is Based on Data input techniques (one is Photogrammetry, another is Laser Techniques). After details study of this, finally in short, we are trying to give the conclusions of this study. In the last, we are trying to give the conclusions of this research paper and also giving a short view for justification and analysis, and present trend for 3D City modeling. This paper gives an overview about the Techniques related with "Generation of Virtual 3-D City models using Geomatics Techniques" and the Applications of Virtual 3D City models. Photogrammetry, (Close range, Aerial, Satellite), Lasergrammetry, GPS, or combination of these modern Geomatics techniques play a major role to create a virtual 3-D City model. Each and every techniques and method has some advantages and some drawbacks. Point cloud model is a modern trend for virtual 3-D city model. Photo-realistic, Scalable, Geo-referenced virtual 3-D City model is a very useful for various kinds of applications such as for planning in Navigation, Tourism, Disasters Management, Transportations, Municipality, Urban Environmental Managements and Real-estate industry. So the Construction of Virtual 3-D city models is a most interesting research topic in recent years.

Regional mapping of soil parent material by machine learning based on point data

NASA Astrophysics Data System (ADS)

Lacoste, Marine; Lemercier, Blandine; Walter, Christian

2011-10-01

A machine learning system (MART) has been used to predict soil parent material (SPM) at the regional scale with a 50-m resolution. The use of point-specific soil observations as training data was tested as a replacement for the soil maps introduced in previous studies, with the aim of generating a more even distribution of training data over the study area and reducing information uncertainty. The 27,020-km 2 study area (Brittany, northwestern France) contains mainly metamorphic, igneous and sedimentary substrates. However, superficial deposits (aeolian loam, colluvial and alluvial deposits) very often represent the actual SPM and are typically under-represented in existing geological maps. In order to calibrate the predictive model, a total of 4920 point soil descriptions were used as training data along with 17 environmental predictors (terrain attributes derived from a 50-m DEM, as well as emissions of K, Th and U obtained by means of airborne gamma-ray spectrometry, geological variables at the 1:250,000 scale and land use maps obtained by remote sensing). Model predictions were then compared: i) during SPM model creation to point data not used in model calibration (internal validation), ii) to the entire point dataset (point validation), and iii) to existing detailed soil maps (external validation). The internal, point and external validation accuracy rates were 56%, 81% and 54%, respectively. Aeolian loam was one of the three most closely predicted substrates. Poor prediction results were associated with uncommon materials and areas with high geological complexity, i.e. areas where existing maps used for external validation were also imprecise. The resultant predictive map turned out to be more accurate than existing geological maps and moreover indicated surface deposits whose spatial coverage is consistent with actual knowledge of the area. This method proves quite useful in predicting SPM within areas where conventional mapping techniques might be too costly or lengthy or where soil maps are insufficient for use as training data. In addition, this method allows producing repeatable and interpretable results, whose accuracy can be assessed objectively.

Classification and assessment of retrieved electron density maps in coherent X-ray diffraction imaging using multivariate analysis.

PubMed

Sekiguchi, Yuki; Oroguchi, Tomotaka; Nakasako, Masayoshi

2016-01-01

Coherent X-ray diffraction imaging (CXDI) is one of the techniques used to visualize structures of non-crystalline particles of micrometer to submicrometer size from materials and biological science. In the structural analysis of CXDI, the electron density map of a sample particle can theoretically be reconstructed from a diffraction pattern by using phase-retrieval (PR) algorithms. However, in practice, the reconstruction is difficult because diffraction patterns are affected by Poisson noise and miss data in small-angle regions due to the beam stop and the saturation of detector pixels. In contrast to X-ray protein crystallography, in which the phases of diffracted waves are experimentally estimated, phase retrieval in CXDI relies entirely on the computational procedure driven by the PR algorithms. Thus, objective criteria and methods to assess the accuracy of retrieved electron density maps are necessary in addition to conventional parameters monitoring the convergence of PR calculations. Here, a data analysis scheme, named ASURA, is proposed which selects the most probable electron density maps from a set of maps retrieved from 1000 different random seeds for a diffraction pattern. Each electron density map composed of J pixels is expressed as a point in a J-dimensional space. Principal component analysis is applied to describe characteristics in the distribution of the maps in the J-dimensional space. When the distribution is characterized by a small number of principal components, the distribution is classified using the k-means clustering method. The classified maps are evaluated by several parameters to assess the quality of the maps. Using the proposed scheme, structure analysis of a diffraction pattern from a non-crystalline particle is conducted in two stages: estimation of the overall shape and determination of the fine structure inside the support shape. In each stage, the most accurate and probable density maps are objectively selected. The validity of the proposed scheme is examined by application to diffraction data that were obtained from an aggregate of metal particles and a biological specimen at the XFEL facility SACLA using custom-made diffraction apparatus.

Comparison of Accuracy Between a Conventional and Two Digital Intraoral Impression Techniques.

PubMed

Malik, Junaid; Rodriguez, Jose; Weisbloom, Michael; Petridis, Haralampos

To compare the accuracy (ie, precision and trueness) of full-arch impressions fabricated using either a conventional polyvinyl siloxane (PVS) material or one of two intraoral optical scanners. Full-arch impressions of a reference model were obtained using addition silicone impression material (Aquasil Ultra; Dentsply Caulk) and two optical scanners (Trios, 3Shape, and CEREC Omnicam, Sirona). Surface matching software (Geomagic Control, 3D Systems) was used to superimpose the scans within groups to determine the mean deviations in precision and trueness (μm) between the scans, which were calculated for each group and compared statistically using one-way analysis of variance with post hoc Bonferroni (trueness) and Games-Howell (precision) tests (IBM SPSS ver 24, IBM UK). Qualitative analysis was also carried out from three-dimensional maps of differences between scans. Means and standard deviations (SD) of deviations in precision for conventional, Trios, and Omnicam groups were 21.7 (± 5.4), 49.9 (± 18.3), and 36.5 (± 11.12) μm, respectively. Means and SDs for deviations in trueness were 24.3 (± 5.7), 87.1 (± 7.9), and 80.3 (± 12.1) μm, respectively. The conventional impression showed statistically significantly improved mean precision (P < .006) and mean trueness (P < .001) compared to both digital impression procedures. There were no statistically significant differences in precision (P = .153) or trueness (P = .757) between the digital impressions. The qualitative analysis revealed local deviations along the palatal surfaces of the molars and incisal edges of the anterior teeth of < 100 μm. Conventional full-arch PVS impressions exhibited improved mean accuracy compared to two direct optical scanners. No significant differences were found between the two digital impression methods.

Direct T2 Quantification of Myocardial Edema in Acute Ischemic Injury

PubMed Central

Verhaert, David; Thavendiranathan, Paaladinesh; Giri, Shivraman; Mihai, Georgeta; Rajagopalan, Sanjay; Simonetti, Orlando P.; Raman, Subha V.

2014-01-01

OBJECTIVES To evaluate the utility of rapid, quantitative T2 mapping compared with conventional T2-weighted imaging in patients presenting with various forms of acute myocardial infarction. BACKGROUND T2-weighted cardiac magnetic resonance (CMR) identifies myocardial edema before the onset of irreversible ischemic injury and has shown value in risk-stratifying patients with chest pain. Clinical acceptance of T2-weighted CMR has, however, been limited by well-known technical problems associated with existing techniques. T2 quantification has recently been shown to overcome these problems; we hypothesized that T2 measurement in infarcted myocardium versus remote regions versus zones of microvascular obstruction in acute myocardial infarction patients could help reduce uncertainty in interpretation of T2-weighted images. METHODS T2 values using a novel mapping technique were prospectively recorded in 16 myocardial segments in 27 patients admitted with acute myocardial infarction. Regional T2 values were averaged in the infarct zone and remote myocardium, both defined by a reviewer blinded to the results of T2 mapping. Myocardial T2 was also measured in a group of 21 healthy volunteers. RESULTS T2 of the infarct zone was 69 ± 6 ms compared with 56 ± 3.4 ms for remote myocardium (p < 0.0001). No difference in T2 was observed between remote myocardium and myocardium of healthy volunteers (56 ± 3.4 ms and 55.5 ± 2.3 ms, respectively, p = NS). T2 mapping allowed for the detection of edematous myocardium in 26 of 27 patients; by comparison, segmented breath-hold T2-weighted short tau inversion recovery images were negative in 7 and uninterpretable in another 2 due to breathing artifacts. Within the infarct zone, areas of microvascular obstruction were characterized by a lower T2 value (59 ± 6 ms) compared with areas with no microvascular obstruction (71.6 ± 10 ms, p < 0.0001). T2 mapping provided consistent high-quality results in patients unable to breath-hold and in those with irregular heart rhythms, in whom short tau inversion recovery often yielded inadequate imaging. CONCLUSIONS Quantitative T2 mapping reliably identifies myocardial edema without the limitations encountered by T2-weighted short tau inversion recovery imaging, and may therefore be clinically more robust in showing acute ischemic injury. PMID:21414575

Cardiac MOLLI T1 mapping at 3.0 T: comparison of patient-adaptive dual-source RF and conventional RF transmission.

PubMed

Rasper, Michael; Nadjiri, Jonathan; Sträter, Alexandra S; Settles, Marcus; Laugwitz, Karl-Ludwig; Rummeny, Ernst J; Huber, Armin M

2017-06-01

To prospectively compare image quality and myocardial T 1 relaxation times of modified Look-Locker inversion recovery (MOLLI) imaging at 3.0 T (T) acquired with patient-adaptive dual-source (DS) and conventional single-source (SS) radiofrequency (RF) transmission. Pre- and post-contrast MOLLI T 1 mapping using SS and DS was acquired in 27 patients. Patient wise and segment wise analysis of T 1 times was performed. The correlation of DS MOLLI measurements with a reference spin echo sequence was analysed in phantom experiments. DS MOLLI imaging reduced T 1 standard deviation in 14 out of 16 myocardial segments (87.5%). Significant reduction of T 1 variance could be obtained in 7 segments (43.8%). DS significantly reduced myocardial T 1 variance in 16 out of 25 patients (64.0%). With conventional RF transmission, dielectric shading artefacts occurred in six patients causing diagnostic uncertainty. No according artefacts were found on DS images. DS image findings were in accordance with conventional T 1 mapping and late gadolinium enhancement (LGE) imaging. Phantom experiments demonstrated good correlation of myocardial T 1 time between DS MOLLI and spin echo imaging. Dual-source RF transmission enhances myocardial T 1 homogeneity in MOLLI imaging at 3.0 T. The reduction of signal inhomogeneities and artefacts due to dielectric shading is likely to enhance diagnostic confidence.

Improved magnetic resonance fingerprinting reconstruction with low-rank and subspace modeling.

PubMed

Zhao, Bo; Setsompop, Kawin; Adalsteinsson, Elfar; Gagoski, Borjan; Ye, Huihui; Ma, Dan; Jiang, Yun; Ellen Grant, P; Griswold, Mark A; Wald, Lawrence L

2018-02-01

This article introduces a constrained imaging method based on low-rank and subspace modeling to improve the accuracy and speed of MR fingerprinting (MRF). A new model-based imaging method is developed for MRF to reconstruct high-quality time-series images and accurate tissue parameter maps (e.g., T 1 , T 2 , and spin density maps). Specifically, the proposed method exploits low-rank approximations of MRF time-series images, and further enforces temporal subspace constraints to capture magnetization dynamics. This allows the time-series image reconstruction problem to be formulated as a simple linear least-squares problem, which enables efficient computation. After image reconstruction, tissue parameter maps are estimated via dictionary-based pattern matching, as in the conventional approach. The effectiveness of the proposed method was evaluated with in vivo experiments. Compared with the conventional MRF reconstruction, the proposed method reconstructs time-series images with significantly reduced aliasing artifacts and noise contamination. Although the conventional approach exhibits some robustness to these corruptions, the improved time-series image reconstruction in turn provides more accurate tissue parameter maps. The improvement is pronounced especially when the acquisition time becomes short. The proposed method significantly improves the accuracy of MRF, and also reduces data acquisition time. Magn Reson Med 79:933-942, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Retention of denture bases fabricated by three different processing techniques – An in vivo study

PubMed Central

Chalapathi Kumar, V. H.; Surapaneni, Hemchand; Ravikiran, V.; Chandra, B. Sarat; Balusu, Srilatha; Reddy, V. Naveen

2016-01-01

Aim: Distortion due to Polymerization shrinkage compromises the retention. To evaluate the amount of retention of denture bases fabricated by conventional, anchorized, and injection molding polymerization techniques. Materials and Methods: Ten completely edentulous patients were selected, impressions were made, and master cast obtained was duplicated to fabricate denture bases by three polymerization techniques. Loop was attached to the finished denture bases to estimate the force required to dislodge them by retention apparatus. Readings were subjected to nonparametric Friedman two-way analysis of variance followed by Bonferroni correction methods and Wilcoxon matched-pairs signed-ranks test. Results: Denture bases fabricated by injection molding (3740 g), anchorized techniques (2913 g) recorded greater retention values than conventional technique (2468 g). Significant difference was seen between these techniques. Conclusions: Denture bases obtained by injection molding polymerization technique exhibited maximum retention, followed by anchorized technique, and least retention was seen in conventional molding technique. PMID:27382542

USING DIRECT-PUSH TOOLS TO MAP HYDROSTRATIGRAPHY AND PREDICT MTBE PLUME DIVING

EPA Science Inventory

Conventional wells for monitoring MTBE contamination at underground storage tank sites are screened a few feet above and a few feet below the water table. At some sites, a plume of contamination in ground water may dive below the screen of conventional monitoring wells and escap...

Lots of legacy soil data are available, but which data do we need to collect for regional land use analysis?

NASA Astrophysics Data System (ADS)

Hendriks, Chantal; Stoorvogel, Jetse; Claessens, Lieven

2015-04-01

In the past, soil surveying techniques were mainly developed for qualitative regional land use analysis (RLUA) like land evaluation and land use planning. Conventional soil survey techniques usually describe soil types according to a soil classification scheme (e.g. Soil Taxonomy and World Reference Base). These soil surveys met the requirements of qualitative land evaluation and land use planning. However, during the last decades there is an increased need for quantitative RLUA resulting in an increased demand for quantitative soil data. The rapid developments in computing technology and the availability of auxiliary information (e.g. remote sensing and digital elevation models) allowed for the development of new soil surveying techniques like digital soil mapping. These new soil surveying techniques aim to produce continuous maps of quantitative functional soil properties. However, RLUA nowadays requires soil data that include a description of the spatial variability of the entire pedon in which correlations between soil properties are retained. Current surveying techniques do not fully fulfil these requirements resulting in a gap between the supply and demand of soil data in RLUA. The gap is caused by the fact that legacy soil data are collected for different purposes and inherently have different assumptions on e.g., soil variability. In this study, some of these assumptions are tested and verified using primary soil data collected during a recent field survey in Machakos and Makueni County (Kenya). Subsequently an ongoing RLUA, the Global Yield Gap Atlas (GYGA) project, is taken as a case study to evaluate the effect of different sources of soil data on the results of the RLUA. The results of the study show that various assumptions underlying the soil survey hamper the quality requirements of soil data for the specific objectives of the RLUA. To give a few examples: mapping soil properties individually ignores correlations between them, soil properties differed significantly between natural and agricultural land, discrete soil mapping units described by a representative soil profile showed internal variability. None of the legacy datasets fitted the requirements of the RLUA. However, resources to collect additional primary soil data are limited. Evaluating legacy data allows us to identify the soil data that we need to collect. Legacy data lack information on e.g. soil management and effective rooting depth, while these data are often required for RLUA. This results in the use of assumptions, estimations and simplifications in a RLUA. The choice of legacy data has a profound effect on the results of a RLUA. The GYGA case study shows for example that different sources of soil input data can lead to differences in simulated water-limited maize yields of up to 3 ton/ha.

Side effects and complications of intraosseous anesthesia and conventional oral anesthesia.

PubMed

Peñarrocha-Oltra, David; Ata-Ali, Javier; Oltra-Moscardó, María-José; Peñarrocha-Diago, María; Peñarrocha, Miguel

2012-05-01

To analyze the side effects and complications following intraosseous anesthesia (IA), comparing them with those of the conventional oral anesthesia techniques. A simple-blind, prospective clinical study was carried out. Each patient underwent two anesthetic techniques: conventional (local infiltration and locoregional anesthetic block) and intraosseous, for respective dental operations. In order to allow comparison of IA versus conventional anesthesia, the two operations were similar and affected the same two teeth in opposite quadrants. Heart rate was recorded in all cases before injection of the anesthetic solution and again 30 seconds after injection. The complications observed after anesthetic administration were recorded. A total of 200 oral anesthetic procedures were carried out in 100 patients. Both IA and conventional anesthesia resulted in a significant increase in heart rate, though the increase was greater with the latter technique. Incidents were infrequent with either anesthetic technique, with no significant differences between them. Regarding the complications, there were significant differences in pain at the injection site, with more intense pain in the case of IA (x2=3.532, p=0.030, Φ2=0.02), while the limitation of oral aperture was more pronounced with conventional anesthesia (x2=5.128, p<0.05, Φ2=0.014). Post-anesthetic biting showed no significant differences (x2=4.082, p=0.121, Φ2=0.009). Both anesthetic techniques significantly increased heart rate, and IA caused comparatively more pain at the injection site, while limited oral aperture was more frequent with conventional anesthesia. Post-anesthetic biting showed no significant differences between the two techniques.

Investigation of gunshot residue patterns using milli-XRF-techniques: first experiences in casework

NASA Astrophysics Data System (ADS)

Schumacher, Rüdiger; Barth, Martin; Neimke, Dieter; Niewöhner, Ludwig

2010-06-01

The investigation of gunshot residue (GSR) patterns for shooting range estimation is usually based on visualizing the lead, copper, or nitrocellulose distributions on targets like fabric or adhesive tape by chemographic color tests. The method usually provides good results but has its drawbacks when it comes to the examination of ammunition containing lead-free primers or bloody clothing. A milli-X-ray fluorescence (m-XRF) spectrometer with a large motorized stage can help to circumvent these problems allowing the acquisition of XRF mappings of relatively large areas (up to 20 x 20 cm) in millimeter resolution within reasonable time (2-10 hours) for almost all elements. First experiences in GSR casework at the Forensic Science Institute of the Bundeskriminalamt (BKA) have shown, that m-XRF is a useful supplementation for conventional methods in shooting ranges estimation, which helps if there are problems in transferring a GSR pattern to secondary targets (e.g. bloody or stained garments) or if there is no suitable color test available for the element of interest. The resulting elemental distributions are a good estimate for the shooting range and can be evaluated by calculating radial distributions or integrated count rates of irregular shaped regions like pieces of human skin which are too small to be investigated with a conventional WD-XRF spectrometer. Beside a mapping mode the milli-XRF offers also point and line scan modes which can also be utilized in gunshot crime investigations as a quick survey tool to identify bullet holes based on the elements present in the wipe ring.

A Retrospective Comparison of Conventional versus Transverse Mini-Incision Technique for Carpal Tunnel Release

PubMed Central

Gülşen, İsmail; Ak, Hakan; Evcılı, Gökhan; Balbaloglu, Özlem; Sösüncü, Enver

2013-01-01

Background. In this retrospective study, we aimed to compare the results of two surgical techniques, conventional and transverse mini-incision. Materials and Methods. 95 patients were operated between 2011 and 2012 in Bitlis State Hospital. 50 patients were operated with conventional technique and 45 of them were operated with minimal transverse incision. Postoperative complications, incision site problems, and the time of starting to use their hands in daily activities were noted. Results. 95 patients were included in the study. The mean age was 48. 87 of them were female and 8 were male. There was no problem of incision site in both of the two surgical techniques. Only in one patient, anesthesia developed in minimal incision technique. The time of starting to use their hands in daily activities was 22,2 days and 17 days in conventional and minimal incision technique, respectively. Conclusion. Two surgical techniques did not show superiority to each other in terms of postoperative complications and incision site problems except the time of starting to use their hands in daily activities. PMID:24396607

Comparison of three different adenoidectomy techniques in children - has the conventional technique been surpassed?

PubMed

Ferreira, Mayra Soares; Mangussi-Gomes, João; Ximendes, Roberta; Evangelista, Anne Rosso; Miranda, Eloá Lumi; Garcia, Leonardo Bomediano; Stamm, Aldo C

2018-01-01

Pharyngeal tonsil hyperplasia is the most frequent cause of nasal obstruction and chronic mouth breathing during childhood. Adenoidectomy is the procedure of choice for the resolution of these symptoms. It is not yet known, however, whether the conventional technique ("blind curettage") has been surpassed by more modern adenoidectomy techniques (video-assisted, with the aid of instruments). This study aimed to compare the conventional adenoidectomy technique with two other emerging techniques, performed in a reference otorhinolaryngology center. This is a prospective and observational study of 33 children submitted to adenoidectomy using 3 different techniques that were followed up for a period of 3 months after surgery. The patients were divided into 3 different groups, according to the adenoidectomy technique: Group A (conventional technique - "blind curettage"); Group B (video-assisted adenoidectomy with microdebrider); Group C (video-assisted adenoidectomy with radiofrequency - Coblation ® ). The surgical time of each procedure was measured, being considered from the moment of insertion of the mouth gag until complete hemostasis was achieved. The questionnaire for quality of life OSA-18 was applied to all caregivers on the day of the surgery and 30-90 days after the procedure. Postoperative complications were also analyzed. For the entire patient sample, there was an improvement in quality of life after the surgery (p < 0.05). When analyzing the evolution of OSA-18 index, all groups showed statistically significant improvement, for all assessed domains. There were no statistically significant differences between the 3 techniques assessed for quality of life improvement after the surgery (p > 0.05). Regarding the duration of the procedure, the conventional technique showed the shortest surgical time when compared to the others (p < 0.05). No postoperative complications were noted, for any patient. The adenoidectomy resulted in improvement of quality of life, and there were no major postoperative complications, for all operated children, regardless of the technique used. The conventional technique was faster when compared to the more modern adenoidectomy techniques. Copyright © 2017 Elsevier B.V. All rights reserved.

Application of the Yoshida-Ruth Techniques to Implicit Integration and Multi-Map Explicit Integration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forest, E.; Bengtsson, J.; Reusch, M.F.

1991-04-01

The full power of Yoshida's technique is exploited to produce an arbitrary order implicit symplectic integrator and multi-map explicit integrator. This implicit integrator uses a characteristic function involving the force term alone. Also we point out the usefulness of the plain Ruth algorithm in computing Taylor series map using the techniques first introduced by Berz in his 'COSY-INFINITY' code.

Earth Resources Technology Satellite data collection project, ERTS - Bolivia. [thematic mapping

NASA Technical Reports Server (NTRS)

Brockmann, C. E.

1974-01-01

The Earth Resources Technology Satellite program of Bolivia has developed a multidisciplinary project to carry out investigations in cartography and to prepare various thematic maps. In cartography, investigations are being carried out with the ERTS-1 images and with existing maps, to determine their application to the preparation of new cartographic products on one hand and on the other to map those regions where the cartography is still deficient. The application of the MSS images to the geological mapping has given more than satisfactory results. Working with conventional photointerpretation, it has been possible to prepare regional geological maps, tectonic maps, studies relative to mining, geomorphological maps, studies relative to petroleum exploration, volcanological maps and maps of hydrologic basins. In agriculture, the ERTS images are used to study land classification and forest and soils mapping.

Time-resolved multicolor two-photon excitation fluorescence microscopy of cells and tissues

NASA Astrophysics Data System (ADS)

Zheng, Wei

2014-11-01

Multilabeling which maps the distribution of different targets is an indispensable technique in many biochemical and biophysical studies. Two-photon excitation fluorescence (TPEF) microscopy of endogenous fluorophores combining with conventional fluorescence labeling techniques such as genetically encoded fluorescent protein (FP) and fluorescent dyes staining could be a powerful tool for imaging living cells. However, the challenge is that the excitation and emission wavelength of these endogenous fluorophores and fluorescent labels are very different. A multi-color ultrafast source is required for the excitation of multiple fluorescence molecules. In this study, we developed a two-photon imaging system with excitations from the pump femtosecond laser and the selected supercontinuum generated from a photonic crystal fiber (PCF). Multiple endogenous fluorophores, fluorescent proteins and fluorescent dyes were excited in their optimal wavelengths simultaneously. A time- and spectral-resolved detection system was used to record the TPEF signals. This detection technique separated the TPEF signals from multiple sources in time and wavelength domains. Cellular organelles such as nucleus, mitochondria, microtubule and endoplasmic reticulum, were clearly revealed in the TPEF images. The simultaneous imaging of multiple fluorophores of cells will greatly aid the study of sub-cellular compartments and protein localization.

Diffusion MRI: literature review in salivary gland tumors.

PubMed

Attyé, A; Troprès, I; Rouchy, R-C; Righini, C; Espinoza, S; Kastler, A; Krainik, A

2017-07-01

Surgical resection is currently the best treatment for salivary gland tumors. A reliable magnetic resonance imaging mapping, encompassing tumor grade, location, and extension may assist safe and effective tumor resection and provide better information for patients regarding potential risks and morbidity after surgical intervention. However, direct examination of the tumor grade and extension using conventional morphological MRI remains difficult, often requiring contrast media injection and complex algorithms on perfusion imaging to estimate the degree of malignancy. In addition, contrast-enhanced MRI technique may be problematic due to the recently demonstrated gadolinium accumulation in the dentate nucleus of the cerebellum. Significant developments in magnetic resonance diffusion imaging, involving voxel-based quantitative analysis through the measurement of the apparent diffusion coefficient, have enhanced our knowledge on the different histopathological salivary tumor grades. Other diffusion imaging-derived techniques, including high-order tractography models, have recently demonstrated their usefulness in assessing the facial nerve location in parotid tumor context. All of these imaging techniques do not require contrast media injection. Our review starts by outlining the physical basis of diffusion imaging, before discussing findings from diagnostic studies testing its usefulness in assessing salivary glands tumors with diffusion MRI. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Map Your Way to Speech Success! Employing Mind Mapping as a Speech Preparation Technique

ERIC Educational Resources Information Center

Paxman, Christina G.

2011-01-01

Mind mapping has gained considerable credibility recently in corporations such as Boeing and Nabisco, as well as in the classroom in terms of preparing for examinations and preparing for speeches. A mind map is a graphic technique for organizing an individual's thoughts and other information. It harnesses the full range of cortical skills--word,…

Mapping ecological risks with a portfolio-based technique: incorporating uncertainty and decision-making preferences

Treesearch

Denys Yemshanov; Frank H. Koch; Mark Ducey; Klaus Koehler

2013-01-01

Geographic mapping of risks is a useful analytical step in ecological risk assessments and in particular, in analyses aimed to estimate risks associated with introductions of invasive organisms. In this paper, we approach invasive species risk mapping as a portfolio allocation problem and apply techniques from decision theory to build an invasion risk map that combines...

Surface mapping of spike potential fields: experienced EEGers vs. computerized analysis.

PubMed

Koszer, S; Moshé, S L; Legatt, A D; Shinnar, S; Goldensohn, E S

1996-03-01

An EEG epileptiform spike focus recorded with scalp electrodes is clinically localized by visual estimation of the point of maximal voltage and the distribution of its surrounding voltages. We compared such estimated voltage maps, drawn by experienced electroencephalographers (EEGers), with a computerized spline interpolation technique employed in the commercially available software package FOCUS. Twenty-two spikes were recorded from 15 patients during long-term continuous EEG monitoring. Maps of voltage distribution from the 28 electrodes surrounding the points of maximum change in slope (the spike maximum) were constructed by the EEGer. The same points of maximum spike and voltage distributions at the 29 electrodes were mapped by computerized spline interpolation and a comparison between the two methods was made. The findings indicate that the computerized spline mapping techniques employed in FOCUS construct voltage maps with similar maxima and distributions as the maps created by experienced EEGers. The dynamics of spike activity, including correlations, are better visualized using the computerized technique than by manual interpretation alone. Its use as a technique for spike localization is accurate and adds information of potential clinical value.

Conversion of KEGG metabolic pathways to SBGN maps including automatic layout

PubMed Central

2013-01-01

Background Biologists make frequent use of databases containing large and complex biological networks. One popular database is the Kyoto Encyclopedia of Genes and Genomes (KEGG) which uses its own graphical representation and manual layout for pathways. While some general drawing conventions exist for biological networks, arbitrary graphical representations are very common. Recently, a new standard has been established for displaying biological processes, the Systems Biology Graphical Notation (SBGN), which aims to unify the look of such maps. Ideally, online repositories such as KEGG would automatically provide networks in a variety of notations including SBGN. Unfortunately, this is non‐trivial, since converting between notations may add, remove or otherwise alter map elements so that the existing layout cannot be simply reused. Results Here we describe a methodology for automatic translation of KEGG metabolic pathways into the SBGN format. We infer important properties of the KEGG layout and treat these as layout constraints that are maintained during the conversion to SBGN maps. Conclusions This allows for the drawing and layout conventions of SBGN to be followed while creating maps that are still recognizably the original KEGG pathways. This article details the steps in this process and provides examples of the final result. PMID:23953132

Parallel imaging of knee cartilage at 3 Tesla.

PubMed

Zuo, Jin; Li, Xiaojuan; Banerjee, Suchandrima; Han, Eric; Majumdar, Sharmila

2007-10-01

To evaluate the feasibility and reproducibility of quantitative cartilage imaging with parallel imaging at 3T and to determine the impact of the acceleration factor (AF) on morphological and relaxation measurements. An eight-channel phased-array knee coil was employed for conventional and parallel imaging on a 3T scanner. The imaging protocol consisted of a T2-weighted fast spin echo (FSE), a 3D-spoiled gradient echo (SPGR), a custom 3D-SPGR T1rho, and a 3D-SPGR T2 sequence. Parallel imaging was performed with an array spatial sensitivity technique (ASSET). The left knees of six healthy volunteers were scanned with both conventional and parallel imaging (AF = 2). Morphological parameters and relaxation maps from parallel imaging methods (AF = 2) showed comparable results with conventional method. The intraclass correlation coefficient (ICC) of the two methods for cartilage volume, mean cartilage thickness, T1rho, and T2 were 0.999, 0.977, 0.964, and 0.969, respectively, while demonstrating excellent reproducibility. No significant measurement differences were found when AF reached 3 despite the low signal-to-noise ratio (SNR). The study demonstrated that parallel imaging can be applied to current knee cartilage quantification at AF = 2 without degrading measurement accuracy with good reproducibility while effectively reducing scan time. Shorter imaging times can be achieved with higher AF at the cost of SNR. (c) 2007 Wiley-Liss, Inc.

Non-conventional solvents in liquid phase microextraction and aqueous biphasic systems.

PubMed

An, Jiwoo; Trujillo-Rodríguez, María J; Pino, Verónica; Anderson, Jared L

2017-06-02

The development of rapid, convenient, and high throughput sample preparation approaches such as liquid phase microextraction techniques have been continuously developed over the last decade. More recently, significant attention has been given to the replacement of conventional organic solvents used in liquid phase microextraction techniques in order to reduce toxic waste and to improve selectivity and/or extraction efficiency. With these objectives, non-conventional solvents have been explored in liquid phase microextraction and aqueous biphasic systems. The utilized non-conventional solvents include ionic liquids, magnetic ionic liquids, and deep eutectic solvents. They have been widely used as extraction solvents or additives in various liquid phase microextraction modes including dispersive liquid-liquid microextraction, single-drop microextraction, hollow fiber-liquid phase microextraction, as well as in aqueous biphasic systems. This review provides an overview into the use of non-conventional solvents in these microextraction techniques in the past 5 years (2012-2016). Analytical applications of the techniques are also discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

A rigorous assessment of tree height measurements obtained using airborne LIDAR and conventional field methods.

Treesearch

Hans-Erik Andersen; Stephen E. Reutebuch; Robert J. McGaughey

2006-01-01

Tree height is an important variable in forest inventory programs but is typically time-consuming and costly to measure in the field using conventional techniques. Airborne light detection and ranging (LIDAR) provides individual tree height measurements that are highly correlated with field-derived measurements, but the imprecision of conventional field techniques does...

Integrating remote sensing with species distribution models; Mapping tamarisk invasions using the Software for Assisted Habitat Modeling (SAHM)

USGS Publications Warehouse

West, Amanda M.; Evangelista, Paul H.; Jarnevich, Catherine S.; Young, Nicholas E.; Stohlgren, Thomas J.; Talbert, Colin; Talbert, Marian; Morisette, Jeffrey; Anderson, Ryan

2016-01-01

Early detection of invasive plant species is vital for the management of natural resources and protection of ecosystem processes. The use of satellite remote sensing for mapping the distribution of invasive plants is becoming more common, however conventional imaging software and classification methods have been shown to be unreliable. In this study, we test and evaluate the use of five species distribution model techniques fit with satellite remote sensing data to map invasive tamarisk (Tamarix spp.) along the Arkansas River in Southeastern Colorado. The models tested included boosted regression trees (BRT), Random Forest (RF), multivariate adaptive regression splines (MARS), generalized linear model (GLM), and Maxent. These analyses were conducted using a newly developed software package called the Software for Assisted Habitat Modeling (SAHM). All models were trained with 499 presence points, 10,000 pseudo-absence points, and predictor variables acquired from the Landsat 5 Thematic Mapper (TM) sensor over an eight-month period to distinguish tamarisk from native riparian vegetation using detection of phenological differences. From the Landsat scenes, we used individual bands and calculated Normalized Difference Vegetation Index (NDVI), Soil-Adjusted Vegetation Index (SAVI), and tasseled capped transformations. All five models identified current tamarisk distribution on the landscape successfully based on threshold independent and threshold dependent evaluation metrics with independent location data. To account for model specific differences, we produced an ensemble of all five models with map output highlighting areas of agreement and areas of uncertainty. Our results demonstrate the usefulness of species distribution models in analyzing remotely sensed data and the utility of ensemble mapping, and showcase the capability of SAHM in pre-processing and executing multiple complex models.

Integrating Remote Sensing with Species Distribution Models; Mapping Tamarisk Invasions Using the Software for Assisted Habitat Modeling (SAHM).

PubMed

West, Amanda M; Evangelista, Paul H; Jarnevich, Catherine S; Young, Nicholas E; Stohlgren, Thomas J; Talbert, Colin; Talbert, Marian; Morisette, Jeffrey; Anderson, Ryan

2016-10-11

Early detection of invasive plant species is vital for the management of natural resources and protection of ecosystem processes. The use of satellite remote sensing for mapping the distribution of invasive plants is becoming more common, however conventional imaging software and classification methods have been shown to be unreliable. In this study, we test and evaluate the use of five species distribution model techniques fit with satellite remote sensing data to map invasive tamarisk (Tamarix spp.) along the Arkansas River in Southeastern Colorado. The models tested included boosted regression trees (BRT), Random Forest (RF), multivariate adaptive regression splines (MARS), generalized linear model (GLM), and Maxent. These analyses were conducted using a newly developed software package called the Software for Assisted Habitat Modeling (SAHM). All models were trained with 499 presence points, 10,000 pseudo-absence points, and predictor variables acquired from the Landsat 5 Thematic Mapper (TM) sensor over an eight-month period to distinguish tamarisk from native riparian vegetation using detection of phenological differences. From the Landsat scenes, we used individual bands and calculated Normalized Difference Vegetation Index (NDVI), Soil-Adjusted Vegetation Index (SAVI), and tasseled capped transformations. All five models identified current tamarisk distribution on the landscape successfully based on threshold independent and threshold dependent evaluation metrics with independent location data. To account for model specific differences, we produced an ensemble of all five models with map output highlighting areas of agreement and areas of uncertainty. Our results demonstrate the usefulness of species distribution models in analyzing remotely sensed data and the utility of ensemble mapping, and showcase the capability of SAHM in pre-processing and executing multiple complex models.

Execution models for mapping programs onto distributed memory parallel computers

NASA Technical Reports Server (NTRS)

Sussman, Alan

1992-01-01

The problem of exploiting the parallelism available in a program to efficiently employ the resources of the target machine is addressed. The problem is discussed in the context of building a mapping compiler for a distributed memory parallel machine. The paper describes using execution models to drive the process of mapping a program in the most efficient way onto a particular machine. Through analysis of the execution models for several mapping techniques for one class of programs, we show that the selection of the best technique for a particular program instance can make a significant difference in performance. On the other hand, the results of benchmarks from an implementation of a mapping compiler show that our execution models are accurate enough to select the best mapping technique for a given program.

Techniques of stapler-based navigational thoracoscopic segmentectomy using virtual assisted lung mapping (VAL-MAP)

PubMed Central

Murayama, Tomonori; Nakajima, Jun

2016-01-01

Anatomical segmentectomies play an important role in oncological lung resection, particularly for ground-glass types of primary lung cancers. This operation can also be applied to metastatic lung tumors deep in the lung. Virtual assisted lung mapping (VAL-MAP) is a novel technique that allows for bronchoscopic multi-spot dye markings to provide “geometric information” to the lung surface, using three-dimensional virtual images. In addition to wedge resections, VAL-MAP has been found to be useful in thoracoscopic segmentectomies, particularly complex segmentectomies, such as combined subsegmentectomies or extended segmentectomies. There are five steps in VAL-MAP-assisted segmentectomies: (I) “standing” stitches along the resection lines; (II) cleaning hilar anatomy; (III) confirming hilar anatomy; (IV) going 1 cm deeper; (V) step-by-step stapling technique. Depending on the anatomy, segmentectomies can be classified into linear (lingular, S6, S2), V- or U-shaped (right S1, left S3, S2b + S3a), and three dimensional (S7, S8, S9, S10) segmentectomies. Particularly three dimensional segmentectomies are challenging in the complexity of stapling techniques. This review focuses on how VAL-MAP can be utilized in segmentectomy, and how this technique can assist the stapling process in even the most challenging ones. PMID:28066675

Implementation and Evaluation of a Mobile Mapping System Based on Integrated Range and Intensity Images for Traffic Signs Localization

NASA Astrophysics Data System (ADS)

Shahbazi, M.; Sattari, M.; Homayouni, S.; Saadatseresht, M.

2012-07-01

Recent advances in positioning techniques have made it possible to develop Mobile Mapping Systems (MMS) for detection and 3D localization of various objects from a moving platform. On the other hand, automatic traffic sign recognition from an equipped mobile platform has recently been a challenging issue for both intelligent transportation and municipal database collection. However, there are several inevitable problems coherent to all the recognition methods completely relying on passive chromatic or grayscale images. This paper presents the implementation and evaluation of an operational MMS. Being distinct from the others, the developed MMS comprises one range camera based on Photonic Mixer Device (PMD) technology and one standard 2D digital camera. The system benefits from certain algorithms to detect, recognize and localize the traffic signs by fusing the shape, color and object information from both range and intensity images. As the calibrating stage, a self-calibration method based on integrated bundle adjustment via joint setup with the digital camera is applied in this study for PMD camera calibration. As the result, an improvement of 83 % in RMS of range error and 72 % in RMS of coordinates residuals for PMD camera, over that achieved with basic calibration is realized in independent accuracy assessments. Furthermore, conventional photogrammetric techniques based on controlled network adjustment are utilized for platform calibration. Likewise, the well-known Extended Kalman Filtering (EKF) is applied to integrate the navigation sensors, namely GPS and INS. The overall acquisition system along with the proposed techniques leads to 90 % true positive recognition and the average of 12 centimetres 3D positioning accuracy.

Implementation and Evaluation of a Mobile Mapping System Based on Integrated Range and Intensity Images for Traffic Signs Localization

NASA Astrophysics Data System (ADS)

Shahbazi, M.; Sattari, M.; Homayouni, S.; Saadatseresht, M.

2012-07-01

Recent advances in positioning techniques have made it possible to develop Mobile Mapping Systems (MMS) for detection and 3D localization of various objects from a moving platform. On the other hand, automatic traffic sign recognition from an equipped mobile platform has recently been a challenging issue for both intelligent transportation and municipal database collection. However, there are several inevitable problems coherent to all the recognition methods completely relying on passive chromatic or grayscale images. This paper presents the implementation and evaluation of an operational MMS. Being distinct from the others, the developed MMS comprises one range camera based on Photonic Mixer Device (PMD) technology and one standard 2D digital camera. The system benefits from certain algorithms to detect, recognize and localize the traffic signs by fusing the shape, color and object information from both range and intensity images. As the calibrating stage, a self-calibration method based on integrated bundle adjustment via joint setup with the digital camera is applied in this study for PMD camera calibration. As the result, an improvement of 83% in RMS of range error and 72% in RMS of coordinates residuals for PMD camera, over that achieved with basic calibration is realized in independent accuracy assessments. Furthermore, conventional photogrammetric techniques based on controlled network adjustment are utilized for platform calibration. Likewise, the well-known Extended Kalman Filtering (EKF) is applied to integrate the navigation sensors, namely GPS and INS. The overall acquisition system along with the proposed techniques leads to 90% true positive recognition and the average of 12 centimetres 3D positioning accuracy.

Develop Advanced Nonlinear Signal Analysis Topographical Mapping System

NASA Technical Reports Server (NTRS)

Jong, Jen-Yi

1997-01-01

During the development of the SSME, a hierarchy of advanced signal analysis techniques for mechanical signature analysis has been developed by NASA and AI Signal Research Inc. (ASRI) to improve the safety and reliability for Space Shuttle operations. These techniques can process and identify intelligent information hidden in a measured signal which is often unidentifiable using conventional signal analysis methods. Currently, due to the highly interactive processing requirements and the volume of dynamic data involved, detailed diagnostic analysis is being performed manually which requires immense man-hours with extensive human interface. To overcome this manual process, NASA implemented this program to develop an Advanced nonlinear signal Analysis Topographical Mapping System (ATMS) to provide automatic/unsupervised engine diagnostic capabilities. The ATMS will utilize a rule-based Clips expert system to supervise a hierarchy of diagnostic signature analysis techniques in the Advanced Signal Analysis Library (ASAL). ASAL will perform automatic signal processing, archiving, and anomaly detection/identification tasks in order to provide an intelligent and fully automated engine diagnostic capability. The ATMS has been successfully developed under this contract. In summary, the program objectives to design, develop, test and conduct performance evaluation for an automated engine diagnostic system have been successfully achieved. Software implementation of the entire ATMS system on MSFC's OISPS computer has been completed. The significance of the ATMS developed under this program is attributed to the fully automated coherence analysis capability for anomaly detection and identification which can greatly enhance the power and reliability of engine diagnostic evaluation. The results have demonstrated that ATMS can significantly save time and man-hours in performing engine test/flight data analysis and performance evaluation of large volumes of dynamic test data.

Modified fluoroscopy-guided sacroiliac joint injection: a technical report.

PubMed

Liliang, Po-Chou; Liang, Cheng-Loong; Lu, Kang; Weng, Hui-Ching; Syu, Fei-Kai

2014-09-01

Sacroiliac joint (SIJ) injection can occasionally be challenging. We describe our experience in using conventional technique, and we developed an adjustment to overcome difficulties incurred. Conventional technique required superimposition of the posterior and anterior SIJ lines. If this technique failed to provide entry into the joint, fluoroscopy was slightly adjusted to obtain an oblique view. Of 50 SIJ injections, 29 (58%; 44-72%) were successfully performed using conventional technique. In another 21 procedures, 18 (85.7%; 64-99%) were subsequently completed using oblique view technique. The medial joint line, viewed from this angle, corresponded to the posterior joint line in 17 cases. The lateral joint line corresponded to the posterior joint line in one case. Oblique view technique can improve the success rate of SIJ injection. Wiley Periodicals, Inc.

Towards mapping of rock walls using a UAV-mounted 2D laser scanner in GPS denied environments

NASA Astrophysics Data System (ADS)

Turner, Glen

In geotechnical engineering, the stability of rock excavations and walls is estimated by using tools that include a map of the orientations of exposed rock faces. However, measuring these orientations by using conventional methods can be time consuming, sometimes dangerous, and is limited to regions of the exposed rock that are reachable by a human. This thesis introduces a 2D, simulated, quadcopter-based rock wall mapping algorithm for GPS denied environments such as underground mines or near high walls on surface. The proposed algorithm employs techniques from the field of robotics known as simultaneous localization and mapping (SLAM) and is a step towards 3D rock wall mapping. Not only are quadcopters agile, but they can hover. This is very useful for confined spaces such as underground or near rock walls. The quadcopter requires sensors to enable self localization and mapping in dark, confined and GPS denied environments. However, these sensors are limited by the quadcopter payload and power restrictions. Because of these restrictions, a light weight 2D laser scanner is proposed. As a first step towards a 3D mapping algorithm, this thesis proposes a simplified scenario in which a simulated 1D laser range finder and 2D IMU are mounted on a quadcopter that is moving on a plane. Because the 1D laser does not provide enough information to map the 2D world from a single measurement, many measurements are combined over the trajectory of the quadcopter. Least Squares Optimization (LSO) is used to optimize the estimated trajectory and rock face for all data collected over the length of a light. Simulation results show that the mapping algorithm developed is a good first step. It shows that by combining measurements over a trajectory, the scanned rock face can be estimated using a lower-dimensional range sensor. A swathing manoeuvre is introduced as a way to promote loop closures within a short time period, thus reducing accumulated error. Some suggestions on how to improve the algorithm are also provided.

Infrared vibrational nanocrystallography and nanoimaging

PubMed Central

Muller, Eric A.; Pollard, Benjamin; Bechtel, Hans A.; van Blerkom, Peter; Raschke, Markus B.

2016-01-01

Molecular solids and polymers can form low-symmetry crystal structures that exhibit anisotropic electron and ion mobility in engineered devices or biological systems. The distribution of molecular orientation and disorder then controls the macroscopic material response, yet it is difficult to image with conventional techniques on the nanoscale. We demonstrated a new form of optical nanocrystallography that combines scattering-type scanning near-field optical microscopy with both optical antenna and tip-selective infrared vibrational spectroscopy. From the symmetry-selective probing of molecular bond orientation with nanometer spatial resolution, we determined crystalline phases and orientation in aggregates and films of the organic electronic material perylenetetracarboxylic dianhydride. Mapping disorder within and between individual nanoscale domains, the correlative hybrid imaging of nanoscale heterogeneity provides insight into defect formation and propagation during growth in functional molecular solids. PMID:27730212

Frequency Representation: Visualization and Clustering of Acoustic Data Using Self-Organizing Maps.

PubMed

Guo, Xinhua; Sun, Song; Yu, Xiantao; Wang, Pan; Nakamura, Kentaro

2017-11-01

Extraction and display of frequency information in three-dimensional (3D) acoustic data are important steps to analyze object characteristics, because the characteristics, such as profiles, sizes, surface structures, and material properties, may show frequency dependence. In this study, frequency representation (FR) based on phase information in multispectral acoustic imaging (MSAI) is proposed to overcome the limit of intensity or amplitude information in image display. Experiments are performed on 3D acoustic data collected from a rigid surface engraved with five different letters. The results show that the proposed FR technique can not only identify the depth of the five letters by the colors representing frequency characteristics but also demonstrate the 3D image of the five letters, providing more detailed characteristics that are unavailable by conventional acoustic imaging.

Trend-Residual Dual Modeling for Detection of Outliers in Low-Cost GPS Trajectories.

PubMed

Chen, Xiaojian; Cui, Tingting; Fu, Jianhong; Peng, Jianwei; Shan, Jie

2016-12-01

Low-cost GPS (receiver) has become a ubiquitous and integral part of our daily life. Despite noticeable advantages such as being cheap, small, light, and easy to use, its limited positioning accuracy devalues and hampers its wide applications for reliable mapping and analysis. Two conventional techniques to remove outliers in a GPS trajectory are thresholding and Kalman-based methods, which are difficult in selecting appropriate thresholds and modeling the trajectories. Moreover, they are insensitive to medium and small outliers, especially for low-sample-rate trajectories. This paper proposes a model-based GPS trajectory cleaner. Rather than examining speed and acceleration or assuming a pre-determined trajectory model, we first use cubic smooth spline to adaptively model the trend of the trajectory. The residuals, i.e., the differences between the trend and GPS measurements, are then further modeled by time series method. Outliers are detected by scoring the residuals at every GPS trajectory point. Comparing to the conventional procedures, the trend-residual dual modeling approach has the following features: (a) it is able to model trajectories and detect outliers adaptively; (b) only one critical value for outlier scores needs to be set; (c) it is able to robustly detect unapparent outliers; and (d) it is effective in cleaning outliers for GPS trajectories with low sample rates. Tests are carried out on three real-world GPS trajectories datasets. The evaluation demonstrates an average of 9.27 times better performance in outlier detection for GPS trajectories than thresholding and Kalman-based techniques.

Clinical feasibility study of combined opto-acoustic and ultrasonic imaging modality providing coregistered functional and anatomical maps of breast tumors

NASA Astrophysics Data System (ADS)

Zalev, Jason; Clingman, Bryan; Smith, Remie J.; Herzog, Don; Miller, Tom; Stavros, A. Thomas; Ermilov, Sergey; Conjusteau, André; Tsyboulski, Dmitri; Oraevsky, Alexander A.; Kist, Kenneth; Dornbluth, N. C.; Otto, Pamela

2013-03-01

We report on findings from the clinical feasibility study of the ImagioTM. Breast Imaging System, which acquires two-dimensional opto-acoustic (OA) images co-registered with conventional ultrasound using a specialized duplex hand-held probe. Dual-wavelength opto-acoustic technology is used to generate parametric maps based upon total hemoglobin and its oxygen saturation in breast tissues. This may provide functional diagnostic information pertaining to tumor metabolism and microvasculature, which is complementary to morphological information obtained with conventional gray-scale ultrasound. We present co-registered opto-acoustic and ultrasonic images of malignant and benign tumors from a recent clinical feasibility study. The clinical results illustrate that the technology may have the capability to improve the efficacy of breast tumor diagnosis. In doing so, it may have the potential to reduce biopsies and to characterize cancers that were not seen well with conventional gray-scale ultrasound alone.

GESFIDE-PROPELLER approach for simultaneous R2 and R2* measurements in the abdomen.

PubMed

Jin, Ning; Guo, Yang; Zhang, Zhuoli; Zhang, Longjiang; Lu, Guangming; Larson, Andrew C

2013-12-01

To investigate the feasibility of combining GESFIDE with PROPELLER sampling approaches for simultaneous abdominal R2 and R2* mapping. R2 and R2* measurements were performed in 9 healthy volunteers and phantoms using the GESFIDE-PROPELLER and the conventional Cartesian-sampling GESFIDE approaches. Images acquired with the GESFIDE-PROPELLER sequence effectively mitigated the respiratory motion artifacts, which were clearly evident in the images acquired using the conventional GESFIDE approach. There was no significant difference between GESFIDE-PROPELLER and reference MGRE R2* measurements (p=0.162) whereas the Cartesian-sampling based GESFIDE methods significantly overestimated R2* values compared to MGRE measurements (p<0.001). The GESFIDE-PROPELLER sequence provided high quality images and accurate abdominal R2 and R2* maps while avoiding the motion artifacts common to the conventional Cartesian-sampling GESFIDE approaches. © 2013 Elsevier Inc. All rights reserved.

GESFIDE-PROPELLER Approach for Simultaneous R2 and R2* Measurements in the Abdomen

PubMed Central

Jin, Ning; Guo, Yang; Zhang, Zhuoli; Zhang, Longjiang; Lu, Guangming; Larson, Andrew C.

2013-01-01

Purpose To investigate the feasibility of combining GESFIDE with PROPELLER sampling approaches for simultaneous abdominal R2 and R2* mapping. Materials and Methods R2 and R2* measurements were performed in 9 healthy volunteers and phantoms using the GESFIDE-PROPELLER and the conventional Cartesian-sampling GESFIDE approaches. Results Images acquired with the GESFIDE-PROPELLER sequence effectively mitigated the respiratory motion artifacts, which were clearly evident in the images acquired using the conventional GESFIDE approach. There were no significant difference between GESFIDE-PROPELLER and reference MGRE R2* measurements (p = 0.162) whereas the Cartesian-sampling based GESFIDE methods significantly overestimated R2* values compared to MGRE measurements (p < 0.001). Conclusion The GESFIDE-PROPELLER sequence provided high quality images and accurate abdominal R2 and R2* maps while avoiding the motion artifacts common to the conventional Cartesian-sampling GESFIDE approaches. PMID:24041478

Dimensional changes of acrylic resin denture bases: conventional versus injection-molding technique.

PubMed

Gharechahi, Jafar; Asadzadeh, Nafiseh; Shahabian, Foad; Gharechahi, Maryam

2014-07-01

Acrylic resin denture bases undergo dimensional changes during polymerization. Injection molding techniques are reported to reduce these changes and thereby improve physical properties of denture bases. The aim of this study was to compare dimensional changes of specimens processed by conventional and injection-molding techniques. SR-Ivocap Triplex Hot resin was used for conventional pressure-packed and SR-Ivocap High Impact was used for injection-molding techniques. After processing, all the specimens were stored in distilled water at room temperature until measured. For dimensional accuracy evaluation, measurements were recorded at 24-hour, 48-hour and 12-day intervals using a digital caliper with an accuracy of 0.01 mm. Statistical analysis was carried out by SPSS (SPSS Inc., Chicago, IL, USA) using t-test and repeated-measures ANOVA. Statistical significance was defined at P<0.05. After each water storage period, the acrylic specimens produced by injection exhibited less dimensional changes compared to those produced by the conventional technique. Curing shrinkage was compensated by water sorption with an increase in water storage time decreasing dimensional changes. Within the limitations of this study, dimensional changes of acrylic resin specimens were influenced by the molding technique used and SR-Ivocap injection procedure exhibited higher dimensional accuracy compared to conventional molding.

Dimensional Changes of Acrylic Resin Denture Bases: Conventional Versus Injection-Molding Technique

PubMed Central

Gharechahi, Jafar; Asadzadeh, Nafiseh; Shahabian, Foad; Gharechahi, Maryam

2014-01-01

Objective: Acrylic resin denture bases undergo dimensional changes during polymerization. Injection molding techniques are reported to reduce these changes and thereby improve physical properties of denture bases. The aim of this study was to compare dimensional changes of specimens processed by conventional and injection-molding techniques. Materials and Methods: SR-Ivocap Triplex Hot resin was used for conventional pressure-packed and SR-Ivocap High Impact was used for injection-molding techniques. After processing, all the specimens were stored in distilled water at room temperature until measured. For dimensional accuracy evaluation, measurements were recorded at 24-hour, 48-hour and 12-day intervals using a digital caliper with an accuracy of 0.01 mm. Statistical analysis was carried out by SPSS (SPSS Inc., Chicago, IL, USA) using t-test and repeated-measures ANOVA. Statistical significance was defined at P<0.05. Results: After each water storage period, the acrylic specimens produced by injection exhibited less dimensional changes compared to those produced by the conventional technique. Curing shrinkage was compensated by water sorption with an increase in water storage time decreasing dimensional changes. Conclusion: Within the limitations of this study, dimensional changes of acrylic resin specimens were influenced by the molding technique used and SR-Ivocap injection procedure exhibited higher dimensional accuracy compared to conventional molding. PMID:25584050

Intraseptal anesthesia: a review of a relevant injection technique.

PubMed

Woodmansey, Karl

2005-01-01

Although overshadowed by intraosseous anesthesia and the periodontal ligament injection, intraseptal anesthesia remains a useful local anesthesia technique for general dentists. Intraseptal anesthesia can be employed with safety and efficacy as an alternative to conventional local infiltration or regional nerve block injections. It also can serve as an adjunctive technique when conventional techniques fail to achieve adequate local anesthesia. This article reviews the intraseptal anesthesia technique, including its indications and limitations.

A flood map based DOI decoding method for block detector: a GATE simulation study.

PubMed

Shi, Han; Du, Dong; Su, Zhihong; Peng, Qiyu

2014-01-01

Positron Emission Tomography (PET) systems using detectors with Depth of Interaction (DOI) capabilities could achieve higher spatial resolution and better image quality than those without DOI. Up till now, most DOI methods developed are not cost-efficient for a whole body PET system. In this paper, we present a DOI decoding method based on flood map for low-cost conventional block detector with four-PMT readout. Using this method, the DOI information can be directly extracted from the DOI-related crystal spot deformation in the flood map. GATE simulations are then carried out to validate the method, confirming a DOI sorting accuracy of 85.27%. Therefore, we conclude that this method has the potential to be applied in conventional detectors to achieve a reasonable DOI measurement without dramatically increasing their complexity and cost of an entire PET system.

Fixed Point Results of Locally Contractive Mappings in Ordered Quasi-Partial Metric Spaces

PubMed Central

Arshad, Muhammad; Ahmad, Jamshaid

2013-01-01

Fixed point results for a self-map satisfying locally contractive conditions on a closed ball in an ordered 0-complete quasi-partial metric space have been established. Instead of monotone mapping, the notion of dominated mappings is applied. We have used weaker metric, weaker contractive conditions, and weaker restrictions to obtain unique fixed points. An example is given which shows that how this result can be used when the corresponding results cannot. Our results generalize, extend, and improve several well-known conventional results. PMID:24062629

Side effects and complications of intraosseous anesthesia and conventional oral anesthesia

PubMed Central

Peñarrocha-Oltra, David; Ata-Ali, Javier; Oltra-Moscardó, María J.; Peñarrocha, Miguel

2012-01-01

Objective: To analyze the side effects and complications following intraosseous anesthesia (IA), comparing them with those of the conventional oral anesthesia techniques. Material and method: A simple-blind, prospective clinical study was carried out. Each patient underwent two anesthetic techniques: conventional (local infiltration and locoregional anesthetic block) and intraosseous, for respective dental operations. In order to allow comparison of IA versus conventional anesthesia, the two operations were similar and affected the same two teeth in opposite quadrants. Heart rate was recorded in all cases before injection of the anesthetic solution and again 30 seconds after injection. The complications observed after anesthetic administration were recorded. Results: A total of 200 oral anesthetic procedures were carried out in 100 patients. Both IA and conventional anesthesia resulted in a significant increase in heart rate, though the increase was greater with the latter technique. Incidents were infrequent with either anesthetic technique, with no significant differences between them. Regarding the complications, there were significant differences in pain at the injection site, with more intense pain in the case of IA (x2=3.532, p=0.030, Φ2=0.02), while the limitation of oral aperture was more pronounced with conventional anesthesia (x2=5.128, p<0.05, Φ2=0.014). Post-anesthetic biting showed no significant differences (x2=4.082, p=0.121, Φ2=0.009). Conclusions: Both anesthetic techniques significantly increased heart rate, and IA caused comparatively more pain at the injection site, while limited oral aperture was more frequent with conventional anesthesia. Post-anesthetic biting showed no significant differences between the two techniques. Key words:Intraosseous anesthesia, oral anesthesia, mandibular block, heart rate, adrenalin, complications. PMID:22143716

A self-trained classification technique for producing 30 m percent-water maps from Landsat data

USGS Publications Warehouse

Rover, Jennifer R.; Wylie, Bruce K.; Ji, Lei

2010-01-01

Small bodies of water can be mapped with moderate-resolution satellite data using methods where water is mapped as subpixel fractions using field measurements or high-resolution images as training datasets. A new method, developed from a regression-tree technique, uses a 30 m Landsat image for training the regression tree that, in turn, is applied to the same image to map subpixel water. The self-trained method was evaluated by comparing the percent-water map with three other maps generated from established percent-water mapping methods: (1) a regression-tree model trained with a 5 m SPOT 5 image, (2) a regression-tree model based on endmembers and (3) a linear unmixing classification technique. The results suggest that subpixel water fractions can be accurately estimated when high-resolution satellite data or intensively interpreted training datasets are not available, which increases our ability to map small water bodies or small changes in lake size at a regional scale.

Differentiation of orbital lymphoma and idiopathic orbital inflammatory pseudotumor: combined diagnostic value of conventional MRI and histogram analysis of ADC maps.

PubMed

Ren, Jiliang; Yuan, Ying; Wu, Yingwei; Tao, Xiaofeng

2018-05-02

The overlap of morphological feature and mean ADC value restricted clinical application of MRI in the differential diagnosis of orbital lymphoma and idiopathic orbital inflammatory pseudotumor (IOIP). In this paper, we aimed to retrospectively evaluate the combined diagnostic value of conventional magnetic resonance imaging (MRI) and whole-tumor histogram analysis of apparent diffusion coefficient (ADC) maps in the differentiation of the two lesions. In total, 18 patients with orbital lymphoma and 22 patients with IOIP were included, who underwent both conventional MRI and diffusion weighted imaging before treatment. Conventional MRI features and histogram parameters derived from ADC maps, including mean ADC (ADC mean ), median ADC (ADC median ), skewness, kurtosis, 10th, 25th, 75th and 90th percentiles of ADC (ADC 10 , ADC 25 , ADC 75 , ADC 90 ) were evaluated and compared between orbital lymphoma and IOIP. Multivariate logistic regression analysis was used to identify the most valuable variables for discriminating. Differential model was built upon the selected variables and receiver operating characteristic (ROC) analysis was also performed to determine the differential ability of the model. Multivariate logistic regression showed ADC 10 (P = 0.023) and involvement of orbit preseptal space (P = 0.029) were the most promising indexes in the discrimination of orbital lymphoma and IOIP. The logistic model defined by ADC 10 and involvement of orbit preseptal space was built, which achieved an AUC of 0.939, with sensitivity of 77.30% and specificity of 94.40%. Conventional MRI feature of involvement of orbit preseptal space and ADC histogram parameter of ADC 10 are valuable in differential diagnosis of orbital lymphoma and IOIP.

Digital Mapping Techniques '10-Workshop Proceedings, Sacramento, California, May 16-19, 2010

USGS Publications Warehouse

Soller, David R.; Soller, David R.

2012-01-01

The Digital Mapping Techniques '10 (DMT'10) workshop was attended by 110 technical experts from 40 agencies, universities, and private companies, including representatives from 19 State geological surveys (see Appendix A). This workshop, hosted by the California Geological Survey, May 16-19, 2010, in Sacramento, California, was similar in nature to the previous 13 meetings (see Appendix B). The meeting was coordinated by the U.S. Geological Survey's (USGS) National Geologic Map Database project. As in the previous meetings, the objective was to foster informal discussion and exchange of technical information. It is with great pleasure that I note that the objective was again successfully met, as attendees continued to share and exchange knowledge and information, and renew friendships and collegial work begun at past DMT workshops. At this meeting, oral and poster presentations and special discussion sessions emphasized (1) methods for creating and publishing map products ("publishing" includes Web-based release); (2) field data capture software and techniques, including the use of LiDAR; (3) digital cartographic techniques; (4) migration of digital maps into ArcGIS Geodatabase format; (5) analytical GIS techniques; and (6) continued development of the National Geologic Map Database.

Estimating generalized skew of the log-Pearson Type III distribution for annual peak floods in Illinois

USGS Publications Warehouse

Oberg, Kevin A.; Mades, Dean M.

1987-01-01

Four techniques for estimating generalized skew in Illinois were evaluated: (1) a generalized skew map of the US; (2) an isoline map; (3) a prediction equation; and (4) a regional-mean skew. Peak-flow records at 730 gaging stations having 10 or more annual peaks were selected for computing station skews. Station skew values ranged from -3.55 to 2.95, with a mean of -0.11. Frequency curves computed for 30 gaging stations in Illinois using the variations of the regional-mean skew technique are similar to frequency curves computed using a skew map developed by the US Water Resources Council (WRC). Estimates of the 50-, 100-, and 500-yr floods computed for 29 of these gaging stations using the regional-mean skew techniques are within the 50% confidence limits of frequency curves computed using the WRC skew map. Although the three variations of the regional-mean skew technique were slightly more accurate than the WRC map, there is no appreciable difference between flood estimates computed using the variations of the regional-mean technique and flood estimates computed using the WRC skew map. (Peters-PTT)

3D silicon breast surface mapping via structured light profilometry

NASA Astrophysics Data System (ADS)

Vairavan, R.; Ong, N. R.; Sauli, Z.; Kirtsaeng, S.; Sakuntasathien, S.; Shahimin, M. M.; Alcain, J. B.; Lai, S. L.; Paitong, P.; Retnasamy, V.

2017-09-01

Digital fringe projection technique is one of the promising optical methods for 3D surface imaging as it demonstrates non contact and non invasive characteristics. The potential of this technique matches the requirement for human body evaluation, as it is vital for disease diagnosis and for treatment option selection. Thus, the digital fringe projection has addressed this requirement with its wide clinical related application and studies. However, the application of this technique for 3D surface mapping of the breast is very minimal. Hence, in this work, the application of digital fringe projection for 3D breast surface mapping is reported. Phase shift fringe projection technique was utilized to perform the 3D breast surface mapping. Maiden results have confirmed the feasibility of using the digital fringe projection method for 3D surface mapping of the breast and it can be extended for breast cancer detection.

The Random-Map Technique: Enhancing Mind-Mapping with a Conceptual Combination Technique to Foster Creative Potential

ERIC Educational Resources Information Center

Malycha, Charlotte P.; Maier, Günter W.

2017-01-01

Although creativity techniques are highly recommended in working environments, their effects have been scarcely investigated. Two cognitive processes are often considered to foster creative potential and are, therefore, taken as a basis for creativity techniques: knowledge activation and conceptual combination. In this study, both processes were…

Low-Cost Ultra-High Spatial and Temporal Resolution Mapping of Intertidal Rock Platforms

NASA Astrophysics Data System (ADS)

Bryson, M.; Johnson-Roberson, M.; Murphy, R.

2012-07-01

Intertidal ecosystems have primarily been studied using field-based sampling; remote sensing offers the ability to collect data over large areas in a snapshot of time which could compliment field-based sampling methods by extrapolating them into the wider spatial and temporal context. Conventional remote sensing tools (such as satellite and aircraft imaging) provide data at relatively course, sub-meter resolutions or with limited temporal resolutions and relatively high costs for small-scale environmental science and ecology studies. In this paper, we describe a low-cost, kite-based imaging system and photogrammetric pipeline that was developed for constructing highresolution, 3D, photo-realistic terrain models of intertidal rocky shores. The processing pipeline uses automatic image feature detection and matching, structure-from-motion and photo-textured terrain surface reconstruction algorithms that require minimal human input and only a small number of ground control points and allow the use of cheap, consumer-grade digital cameras. The resulting maps combine colour and topographic information at sub-centimeter resolutions over an area of approximately 100m, thus enabling spatial properties of the intertidal environment to be determined across a hierarchy of spatial scales. Results of the system are presented for an intertidal rock platform at Cape Banks, Sydney, Australia. Potential uses of this technique include mapping of plant (micro- and macro-algae) and animal (e.g. gastropods) assemblages at multiple spatial and temporal scales.

Mapping soil landscape as spatial continua: The Neural Network Approach

NASA Astrophysics Data System (ADS)

Zhu, A.-Xing

2000-03-01

A neural network approach was developed to populate a soil similarity model that was designed to represent soil landscape as spatial continua for hydroecological modeling at watersheds of mesoscale size. The approach employs multilayer feed forward neural networks. The input to the network was data on a set of soil formative environmental factors; the output from the network was a set of similarity values to a set of prescribed soil classes. The network was trained using a conjugate gradient algorithm in combination with a simulated annealing technique to learn the relationships between a set of prescribed soils and their environmental factors. Once trained, the network was used to compute for every location in an area the similarity values of the soil to the set of prescribed soil classes. The similarity values were then used to produce detailed soil spatial information. The approach also included a Geographic Information System procedure for selecting representative training and testing samples and a process of determining the network internal structure. The approach was applied to soil mapping in a watershed, the Lubrecht Experimental Forest, in western Montana. The case study showed that the soil spatial information derived using the neural network approach reveals much greater spatial detail and has a higher quality than that derived from the conventional soil map. Implications of this detailed soil spatial information for hydroecological modeling at the watershed scale are also discussed.

Volume Computation of a Stockpile - a Study Case Comparing GPS and Uav Measurements in AN Open Pit Quarry

NASA Astrophysics Data System (ADS)

Raeva, P. L.; Filipova, S. L.; Filipov, D. G.

2016-06-01

The following paper aims to test and evaluate the accuracy of UAV data for volumetric measurements to the conventional GNSS techniques. For this purpose, an appropriate open pit quarry has been chosen. Two sets of measurements were performed. Firstly, a stockpile was measured by GNSS technologies and later other terrestrial GNSS measurements for modelling the berms of the quarry were taken. Secondly, the area of the whole quarry including the stockpile site was mapped by a UAV flight. Having considered how dynamic our world is, new techniques and methods should be presented in numerous fields. For instance, the management of an open pit quarry requires gaining, processing and storing a large amount of information which is constantly changing with time. Fast and precise acquisition of measurements regarding the process taking place in a quarry is the key to an effective and stable maintenance. In other words, this means getting an objective evaluations of the processes, using up-to-date technologies and reliable accuracy of the results. Often legislations concerning mine engineering state that the volumetric calculations are to present ±3% accuracy of the whole amount. On one hand, extremely precise measurements could be performed by GNSS technologies, however, it could be really time consuming. On the other hand, UAV photogrammetry presents a fast, accurate method for mapping large areas and calculating stockpiles volumes. The study case was performed as a part of a master thesis.

The Sine Method: An Alternative Height Measurement Technique

Treesearch

Don C. Bragg; Lee E. Frelich; Robert T. Leverett; Will Blozan; Dale J. Luthringer

2011-01-01

Height is one of the most important dimensions of trees, but few observers are fully aware of the consequences of the misapplication of conventional height measurement techniques. A new approach, the sine method, can improve height measurement by being less sensitive to the requirements of conventional techniques (similar triangles and the tangent method). We studied...

Hot-wire anemometry in hypersonic helium flow

NASA Technical Reports Server (NTRS)

Wagner, R. D.; Weinstein, L. M.

1974-01-01

Hot-wire anemometry techniques are described that have been developed and used for hypersonic-helium-flow studies. The short run time available dictated certain innovations in applying conventional hot-wire techniques. Some examples are given to show the application of the techniques used. Modifications to conventional equipment are described, including probe modifications and probe heating controls.

Comparison of surgically induced astigmatism in patients with horizontal rectus muscle recession

PubMed Central

Çakmak, Harun; Kocatürk, Tolga; Dündar, Sema Oruç

2014-01-01

AIM To compare surgically induced astigmatism (SIA) following horizontal rectus muscle recession surgery between suspension recession with both the “hang-back” technique and conventional recession technique. METHODS Totally, 48 eyes of 24 patients who had undergone horizontal rectus muscle recession surgery were reviewed retrospectively. The patients were divided into two groups. Twelve patients were operated on by the hang-back technique (Group 1), and 12 by the conventional recession technique (Group 2). SIA was calculated on the 1st wk, 1st and in the 3rd mo after surgery using the SIA calculator. RESULTS SIA was statistically higher in the Group 1 all postoperative follow-up. SIA was the highest in the 1st wk, and decreased gradually in both groups. CONCLUSION The suspension recession technique induced much more SIA than the conventional recession technique. This difference also continued in the following visits. Therefore, the refractive power should be checked postoperatively in order to avoid refractive amblyopia. Conventional recession surgery should be the preferred method so as to minimize the postoperative refractive changes in patients with amblyopia. PMID:25161948

RECENT DEVELOPMENTS IN THE U. S. GEOLOGICAL SURVEY'S LANDSAT IMAGE MAPPING PROGRAM.

USGS Publications Warehouse

Brownworth, Frederick S.; Rohde, Wayne G.

1986-01-01

At the 1984 ASPRS-ACSM Convention in Washington, D. C. a paper on 'The Emerging U. S. Geological Survey Image Mapping Program' was presented that discussed recent satellite image mapping advancements and published products. Since then Landsat image mapping has become an integral part of the National Mapping Program. The Survey currently produces about 20 Landsat multispectral scanner (MSS) and Thematic Mapper (TM) image map products annually at 1:250,000 and 1:100,000 scales, respectively. These Landsat image maps provide users with a regional or synoptic view of an area. The resultant geographical presentation of the terrain and cultural features will help planners and managers make better decisions regarding the use of our national resources.

Comparison of computer-assisted surgery with conventional technique for the treatment of axial distal phalanx fractures in horses: an in vitro study.

PubMed

Andritzky, Juliane; Rossol, Melanie; Lischer, Christoph; Auer, Joerg A

2005-01-01

To compare the precision obtained with computer-assisted screw insertion for treatment of mid-sagittal articular fractures of the distal phalanx (P3) with results achieved with a conventional technique. In vitro experimental study. Thirty-two cadaveric equine limbs. Four groups of 8 limbs were studied. Either 1 or 2 screws were inserted perpendicular to an imaginary axial fracture of P3 using computer-assisted surgery (CAS) or conventional technique. Screw insertion time, predetermined screw length, inserted screw length, fit of the screw, and errors in placement were recorded. CAS technique took 15-20 minutes longer but resulted in greater precision of screw length and placement compared with the conventional technique. Improved precision in screw insertion with CAS makes insertion of 2 screws possible for repair of mid-sagittal P3 fractures. CAS although expensive improves precision in screw insertion into P3 and consequently should yield improved clinical outcome.

MAP-Motivated Carrier Synchronization of GMSK Based on the Laurent AMP Representation

NASA Technical Reports Server (NTRS)

Simon, M. K.

1998-01-01

Using the MAP estimation approach to carrier synchronization of digital modulations containing ISI together with a two pulse stream AMP representation of GMSK, it is possible to obtain an optimum closed loop configuration in the same manner as has been previously proposed for other conventional modulations with ISI.

Technology Toolkit: Literary Road Trip

ERIC Educational Resources Information Center

Hayes, Sandy

2007-01-01

Hayes recognizes the value of connections kids make when authors and settings strike a familiar note. She invites readers to participate in a new event at this year's NCTE Annual Convention in New York City: The 21st-Century Literary Map Project gallery, where attendees are encouraged to examine affiliates' literary maps, see digital or…

Geographic information system (GIS)-based maps of Appalachian basin oil and gas fields: Chapter C.2 in Coal and petroleum resources in the Appalachian basin: distribution, geologic framework, and geochemical character

USGS Publications Warehouse

Ryder, Robert T.; Kinney, Scott A.; Suitt, Stephen E.; Merrill, Matthew D.; Trippi, Michael H.; Ruppert, Leslie F.; Ryder, Robert T.

2014-01-01

In 2006 and 2007, the greenline Appalachian basin field maps were digitized under the supervision of Scott Kinney and converted to geographic information system (GIS) files for chapter I.1 (this volume). By converting these oil and gas field maps to a digital format and maintaining the field names where noted, they are now available for a variety of oil and gas and possibly carbon-dioxide sequestration projects. Having historical names assigned to known digitized conventional fields provides a convenient classification scheme into which cumulative production and ultimate field-size databases can be organized. Moreover, as exploratory and development drilling expands across the basin, many previously named fields that were originally treated as conventional fields have evolved into large, commonly unnamed continuous-type accumulations. These new digital maps will facilitate a comparison between EUR values from recently drilled, unnamed parts of continuous accumulations and EUR values from named fields discovered early during the exploration cycle of continuous accumulations.

Review and evaluation of recent developments in melic inlet dynamic flow distortion prediction and computer program documentation and user's manual estimating maximum instantaneous inlet flow distortion from steady-state total pressure measurements with full, limited, or no dynamic data

NASA Technical Reports Server (NTRS)

Schweikhard, W. G.; Dennon, S. R.

1986-01-01

A review of the Melick method of inlet flow dynamic distortion prediction by statistical means is provided. These developments include the general Melick approach with full dynamic measurements, a limited dynamic measurement approach, and a turbulence modelling approach which requires no dynamic rms pressure fluctuation measurements. These modifications are evaluated by comparing predicted and measured peak instantaneous distortion levels from provisional inlet data sets. A nonlinear mean-line following vortex model is proposed and evaluated as a potential criterion for improving the peak instantaneous distortion map generated from the conventional linear vortex of the Melick method. The model is simplified to a series of linear vortex segments which lay along the mean line. Maps generated with this new approach are compared with conventionally generated maps, as well as measured peak instantaneous maps. Inlet data sets include subsonic, transonic, and supersonic inlets under various flight conditions.

Beyond data collection in digital mapping: interpretation, sketching and thought process elements in geological map making

NASA Astrophysics Data System (ADS)

Watkins, Hannah; Bond, Clare; Butler, Rob

2016-04-01

Geological mapping techniques have advanced significantly in recent years from paper fieldslips to Toughbook, smartphone and tablet mapping; but how do the methods used to create a geological map affect the thought processes that result in the final map interpretation? Geological maps have many key roles in the field of geosciences including understanding geological processes and geometries in 3D, interpreting geological histories and understanding stratigraphic relationships in 2D and 3D. Here we consider the impact of the methods used to create a map on the thought processes that result in the final geological map interpretation. As mapping technology has advanced in recent years, the way in which we produce geological maps has also changed. Traditional geological mapping is undertaken using paper fieldslips, pencils and compass clinometers. The map interpretation evolves through time as data is collected. This interpretive process that results in the final geological map is often supported by recording in a field notebook, observations, ideas and alternative geological models explored with the use of sketches and evolutionary diagrams. In combination the field map and notebook can be used to challenge the map interpretation and consider its uncertainties. These uncertainties and the balance of data to interpretation are often lost in the creation of published 'fair' copy geological maps. The advent of Toughbooks, smartphones and tablets in the production of geological maps has changed the process of map creation. Digital data collection, particularly through the use of inbuilt gyrometers in phones and tablets, has changed smartphones into geological mapping tools that can be used to collect lots of geological data quickly. With GPS functionality this data is also geospatially located, assuming good GPS connectivity, and can be linked to georeferenced infield photography. In contrast line drawing, for example for lithological boundary interpretation and sketching, is yet to find the digital flow that is achieved with pencil on notebook page or map. Free-form integrated sketching and notebook functionality in geological mapping software packages is in its nascence. Hence, the result is a tendency for digital geological mapping to focus on the ease of data collection rather than on the thoughts and careful observations that come from notebook sketching and interpreting boundaries on a map in the field. The final digital geological map can be assessed for when and where data was recorded, but the thought processes of the mapper are less easily assessed, and the use of observations and sketching to generate ideas and interpretations maybe inhibited by reliance on digital mapping methods. All mapping methods used have their own distinct advantages and disadvantages and with more recent technologies both hardware and software issues have arisen. We present field examples of using conventional fieldslip mapping, and compare these with more advanced technologies to highlight some of the main advantages and disadvantages of each method and discuss where geological mapping may be going in the future.

Key issues in decomposing fMRI during naturalistic and continuous music experience with independent component analysis.

PubMed

Cong, Fengyu; Puoliväli, Tuomas; Alluri, Vinoo; Sipola, Tuomo; Burunat, Iballa; Toiviainen, Petri; Nandi, Asoke K; Brattico, Elvira; Ristaniemi, Tapani

2014-02-15

Independent component analysis (ICA) has been often used to decompose fMRI data mostly for the resting-state, block and event-related designs due to its outstanding advantage. For fMRI data during free-listening experiences, only a few exploratory studies applied ICA. For processing the fMRI data elicited by 512-s modern tango, a FFT based band-pass filter was used to further pre-process the fMRI data to remove sources of no interest and noise. Then, a fast model order selection method was applied to estimate the number of sources. Next, both individual ICA and group ICA were performed. Subsequently, ICA components whose temporal courses were significantly correlated with musical features were selected. Finally, for individual ICA, common components across majority of participants were found by diffusion map and spectral clustering. The extracted spatial maps (by the new ICA approach) common across most participants evidenced slightly right-lateralized activity within and surrounding the auditory cortices. Meanwhile, they were found associated with the musical features. Compared with the conventional ICA approach, more participants were found to have the common spatial maps extracted by the new ICA approach. Conventional model order selection methods underestimated the true number of sources in the conventionally pre-processed fMRI data for the individual ICA. Pre-processing the fMRI data by using a reasonable band-pass digital filter can greatly benefit the following model order selection and ICA with fMRI data by naturalistic paradigms. Diffusion map and spectral clustering are straightforward tools to find common ICA spatial maps. Copyright © 2013 Elsevier B.V. All rights reserved.

Cartographic mapping study

NASA Technical Reports Server (NTRS)

Wilson, C.; Dye, R.; Reed, L.

1982-01-01

The errors associated with planimetric mapping of the United States using satellite remote sensing techniques are analyzed. Assumptions concerning the state of the art achievable for satellite mapping systems and platforms in the 1995 time frame are made. An analysis of these performance parameters is made using an interactive cartographic satellite computer model, after first validating the model using LANDSAT 1 through 3 performance parameters. An investigation of current large scale (1:24,000) US National mapping techniques is made. Using the results of this investigation, and current national mapping accuracy standards, the 1995 satellite mapping system is evaluated for its ability to meet US mapping standards for planimetric and topographic mapping at scales of 1:24,000 and smaller.

In silico comparison of the reproducibility of full-arch implant provisional restorations to final restoration between a 3D Scan/CAD/CAM technique and the conventional method.

PubMed

Mino, Takuya; Maekawa, Kenji; Ueda, Akihiro; Higuchi, Shizuo; Sejima, Junichi; Takeuchi, Tetsuo; Hara, Emilio Satoshi; Kimura-Ono, Aya; Sonoyama, Wataru; Kuboki, Takuo

2015-04-01

The aim of this article was to investigate the accuracy in the reproducibility of full-arch implant provisional restorations to final restorations between a 3D Scan/CAD/CAM technique and the conventional method. We fabricated two final restorations for rehabilitation of maxillary and mandibular complete edentulous area and performed a computer-based comparative analysis of the accuracy in the reproducibility of the provisional restoration to final restoration between a 3D scanning and CAD/CAM (Scan/CAD/CAM) technique and the conventional silicone-mold transfer technique. Final restorations fabricated either by the conventional or Scan/CAD/CAM method were successfully installed in the patient. The total concave/convex volume discrepancy observed with the Scan/CAD/CAM technique was 503.50mm(3) and 338.15 mm(3) for maxillary and mandibular implant-supported prostheses (ISPs), respectively. On the other hand, total concave/convex volume discrepancy observed with the conventional method was markedly high (1106.84 mm(3) and 771.23 mm(3) for maxillary and mandibular ISPs, respectively). The results of the present report suggest that Scan/CAD/CAM method enables a more precise and accurate transfer of provisional restorations to final restorations compared to the conventional method. Copyright © 2014 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

A single-gradient junction technique to replace multiple-junction shifts for craniospinal irradiation treatment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hadley, Austin; Ding, George X., E-mail: george.ding@vanderbilt.edu

2014-01-01

Craniospinal irradiation (CSI) requires abutting fields at the cervical spine. Junction shifts are conventionally used to prevent setup error–induced overdosage/underdosage from occurring at the same location. This study compared the dosimetric differences at the cranial-spinal junction between a single-gradient junction technique and conventional multiple-junction shifts and evaluated the effect of setup errors on the dose distributions between both techniques for a treatment course and single fraction. Conventionally, 2 lateral brain fields and a posterior spine field(s) are used for CSI with weekly 1-cm junction shifts. We retrospectively replanned 4 CSI patients using a single-gradient junction between the lateral brain fieldsmore » and the posterior spine field. The fields were extended to allow a minimum 3-cm field overlap. The dose gradient at the junction was achieved using dose painting and intensity-modulated radiation therapy planning. The effect of positioning setup errors on the dose distributions for both techniques was simulated by applying shifts of ± 3 and 5 mm. The resulting cervical spine doses across the field junction for both techniques were calculated and compared. Dose profiles were obtained for both a single fraction and entire treatment course to include the effects of the conventional weekly junction shifts. Compared with the conventional technique, the gradient-dose technique resulted in higher dose uniformity and conformity to the target volumes, lower organ at risk (OAR) mean and maximum doses, and diminished hot spots from systematic positioning errors over the course of treatment. Single-fraction hot and cold spots were improved for the gradient-dose technique. The single-gradient junction technique provides improved conformity, dose uniformity, diminished hot spots, lower OAR mean and maximum dose, and one plan for the entire treatment course, which reduces the potential human error associated with conventional 4-shifted plans.« less

Whole-tumor histogram analysis of the cerebral blood volume map: tumor volume defined by 11C-methionine positron emission tomography image improves the diagnostic accuracy of cerebral glioma grading.

PubMed

Wu, Rongli; Watanabe, Yoshiyuki; Arisawa, Atsuko; Takahashi, Hiroto; Tanaka, Hisashi; Fujimoto, Yasunori; Watabe, Tadashi; Isohashi, Kayako; Hatazawa, Jun; Tomiyama, Noriyuki

2017-10-01

This study aimed to compare the tumor volume definition using conventional magnetic resonance (MR) and 11C-methionine positron emission tomography (MET/PET) images in the differentiation of the pre-operative glioma grade by using whole-tumor histogram analysis of normalized cerebral blood volume (nCBV) maps. Thirty-four patients with histopathologically proven primary brain low-grade gliomas (n = 15) and high-grade gliomas (n = 19) underwent pre-operative or pre-biopsy MET/PET, fluid-attenuated inversion recovery, dynamic susceptibility contrast perfusion-weighted magnetic resonance imaging, and contrast-enhanced T1-weighted at 3.0 T. The histogram distribution derived from the nCBV maps was obtained by co-registering the whole tumor volume delineated on conventional MR or MET/PET images, and eight histogram parameters were assessed. The mean nCBV value had the highest AUC value (0.906) based on MET/PET images. Diagnostic accuracy significantly improved when the tumor volume was measured from MET/PET images compared with conventional MR images for the parameters of mean, 50th, and 75th percentile nCBV value (p = 0.0246, 0.0223, and 0.0150, respectively). Whole-tumor histogram analysis of CBV map provides more valuable histogram parameters and increases diagnostic accuracy in the differentiation of pre-operative cerebral gliomas when the tumor volume is derived from MET/PET images.

Computer-composite mapping for geologists

USGS Publications Warehouse

van Driel, J.N.

1980-01-01

A computer program for overlaying maps has been tested and evaluated as a means for producing geologic derivative maps. Four maps of the Sugar House Quadrangle, Utah, were combined, using the Multi-Scale Data Analysis and Mapping Program, in a single composite map that shows the relative stability of the land surface during earthquakes. Computer-composite mapping can provide geologists with a powerful analytical tool and a flexible graphic display technique. Digitized map units can be shown singly, grouped with different units from the same map, or combined with units from other source maps to produce composite maps. The mapping program permits the user to assign various values to the map units and to specify symbology for the final map. Because of its flexible storage, easy manipulation, and capabilities of graphic output, the composite-mapping technique can readily be applied to mapping projects in sedimentary and crystalline terranes, as well as to maps showing mineral resource potential. ?? 1980 Springer-Verlag New York Inc.