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Sample records for coordination dynamics measuring

  1. Social coordination dynamics: Measuring human bonding

    PubMed Central

    Oullier, Olivier; de Guzman, Gonzalo C.; Jantzen, Kelly J.; Lagarde, Julien; Kelso, J.A. Scott

    2007-01-01

    Spontaneous social coordination has been extensively described in natural settings but so far no controlled methodological approaches have been employed that systematically advance investigations into the possible self-organized nature of bond formation and dissolution between humans. We hypothesized that, under certain contexts, spontaneous synchrony -a well-described phenomenon in biological and physical settings- could emerge spontaneously between humans as a result of information exchange. Here, a new way to quantify interpersonal interactions in real time is proposed. In a simple experimental paradigm, pairs of participants facing each other were required to actively produce actions, while provided (or not) with the vision of similar actions being performed by someone else. New indices of interpersonal coordination, inspired by the theoretical framework of coordination dynamics (based on relative phase and frequency overlap between movements of individuals forming a pair) were developed and used. Results revealed that spontaneous phase synchrony (i.e., unintentional in-phase coordinated behavior) between two people emerges as soon as they exchange visual information, even if they are not explicitly instructed to coordinate with each other. Using the same tools, we also quantified the degree to which the behavior of each individual remained influenced by the social encounter even after information exchange had been removed, apparently a kind of social memory. PMID:18552971

  2. The partial least-squares regression analysis of impact factors of coordinate measuring machine dynamic error

    NASA Astrophysics Data System (ADS)

    Zhang, Mei; Fei, Yetai; Sheng, Li; Ma, Xiushui; Yang, Hong-tao

    2008-12-01

    The reasons why the coordinate measuring machine (CMM) dynamic error exists are complicate. And there are many elements which influence the error. So it is hard to build an accurate model. For the sake of attaining a model which not only avoided analyzing complex error sources and the interactions among them, but also solved the multiple colinearity among the variables. This paper adopted the Partial Least-Squares Regression (PLSR) to build model. The model takes 3D coordinates (X, Y, Z) and the moving velocity as the independent variable and takes the CMM dynamic error value as the dependent variable. The experimental results show that the model can be easily explained. At the same time the results show the magnitude and direction of the independent variable influencing the dependent variable.

  3. Coordinate Standard Measurement Development

    SciTech Connect

    Hanshaw, R.A.

    2000-02-18

    A Shelton Precision Interferometer Base, which is used for calibration of coordinate standards, was improved through hardware replacement, software geometry error correction, and reduction of vibration effects. Substantial increases in resolution and reliability, as well as reduction in sampling time, were achieved through hardware replacement; vibration effects were reduced substantially through modification of the machine component dampening and software routines; and the majority of the machine's geometry error was corrected through software geometry error correction. Because of these modifications, the uncertainty of coordinate standards calibrated on this device has been reduced dramatically.

  4. Coordination Dynamics in Cognitive Neuroscience

    PubMed Central

    Bressler, Steven L.; Kelso, J. A. Scott

    2016-01-01

    Many researchers and clinicians in cognitive neuroscience hold to a modular view of cognitive function in which the cerebral cortex operates by the activation of areas with circumscribed elementary cognitive functions. Yet an ongoing paradigm shift to a dynamic network perspective is underway. This new viewpoint treats cortical function as arising from the coordination dynamics within and between cortical regions. Cortical coordination dynamics arises due to the unidirectional influences imposed on a cortical area by inputs from other areas that project to it, combined with the projection reciprocity that characterizes cortical connectivity and gives rise to reentrant processing. As a result, cortical dynamics exhibits both segregative and integrative tendencies and gives rise to both cooperative and competitive relations within and between cortical areas that are hypothesized to underlie the emergence of cognition in brains.

  5. Coordination Dynamics in Cognitive Neuroscience

    PubMed Central

    Bressler, Steven L.; Kelso, J. A. Scott

    2016-01-01

    Many researchers and clinicians in cognitive neuroscience hold to a modular view of cognitive function in which the cerebral cortex operates by the activation of areas with circumscribed elementary cognitive functions. Yet an ongoing paradigm shift to a dynamic network perspective is underway. This new viewpoint treats cortical function as arising from the coordination dynamics within and between cortical regions. Cortical coordination dynamics arises due to the unidirectional influences imposed on a cortical area by inputs from other areas that project to it, combined with the projection reciprocity that characterizes cortical connectivity and gives rise to reentrant processing. As a result, cortical dynamics exhibits both segregative and integrative tendencies and gives rise to both cooperative and competitive relations within and between cortical areas that are hypothesized to underlie the emergence of cognition in brains. PMID:27695395

  6. Coordinate measuring system

    DOEpatents

    Carlisle, Keith

    2003-04-08

    An apparatus and method is utilized to measure relative rigid body motion between two bodies by measuring linear motion in the principal axis and linear motion in an orthogonal axis. From such measurements it is possible to obtain displacement, departure from straightness, and angular displacement from the principal axis of a rigid body.

  7. Modeling and prototyping of a fiber Bragg grating-based dynamic micro-coordinate measuring machine probe

    NASA Astrophysics Data System (ADS)

    Liu, Fangfang; Chen, Lijuan; Wang, Jingfan; Xia, Haojie; Li, Ruijun; Yu, Liandong; Fei, Yetai

    2016-02-01

    Higher-accuracy measurements of the 3D metrology of nano- and micro-structures are increasingly demanded. This paper details the prototyping of a novel 3D micro-scale coordinate measuring machine probe based on fiber Bragg grating sensors for true 3D measurements at micro- and nanometer scales. A new manufacturing technique for the high-precision cantilever used in the probe is also reported. Simulations are performed during the design and testing to help to test important aspects of the probe and to gain understanding about the influence of the probe geometrical parameters on the sensor sensitivity. The initial performance of the probe has been tested in both the vertical and horizontal directions, and the characterization results are promising. Further experimental results demonstrate that the probe is not affected by surface interaction forces.

  8. Measuring motor coordination in mice.

    PubMed

    Deacon, Robert M J

    2013-01-01

    Mice are increasingly being used in behavioral neuroscience, largely replacing rats as the behaviorist's animal of choice. Before aspects of behavior such as emotionality or cognition can be assessed, however, it is vital to determine whether the motor capabilities of e.g. a mutant or lesioned mouse allow such an assessment. Performance on a maze task requiring strength and coordination, such as the Morris water maze, might well be impaired in a mouse by motor, rather than cognitive, impairments, so it is essential to selectively dissect the latter from the former. For example, sensorimotor impairments caused by NMDA antagonists have been shown to impair water maze performance(2). Motor coordination has traditionally been assessed in mice and rats by the rotarod test, in which the animal is placed on a horizontal rod that rotates about its long axis; the animal must walk forwards to remain upright and not fall off. Both set speed and accelerating versions of the rotarod are available. The other three tests described in this article (horizontal bar, static rods and parallel bars) all measure coordination on static apparatus. The horizontal bar also requires strength for adequate performance, particularly of the forelimbs as the mouse initially grips the bar just with the front paws. Adult rats do not perform well on tests such as the static rods and parallel bars (personal observations); they appear less well coordinated than mice. I have only tested male rats, however, and male mice seem generally less well coordinated than females. Mice appear to have a higher strength:weight ratio than rats; the Latin name, Mus musculus, seems entirely appropriate. The rotarod, the variations of the foot fault test(12) or the Catwalk (Noldus)(15) apparatus are generally used to assess motor coordination in rats. PMID:23748408

  9. Concurrent Cognitive Task Modulates Coordination Dynamics

    ERIC Educational Resources Information Center

    Pellecchia, Geraldine L.; Shockley, Kevin; Turvey, M. T.

    2005-01-01

    Does a concurrent cognitive task affect the dynamics of bimanual rhythmic coordination? In-phase coordination was performed under manipulations of phase detuning and movement frequency and either singly or in combination with an arithmetic task. Predicted direction-specific shifts in stable relative phase from 0 degrees due to detuning and…

  10. Neuroimaging Coordination Dynamics in the Sport Sciences

    PubMed Central

    Jantzen, Kelly J.; Oullier, Olivier; Kelso, J.A. Scott

    2008-01-01

    Key methodological issues for designing, analyzing, and interpreting neuroimaging experiments are presented from the perspective of the framework of Coordination Dynamics. To this end, a brief overview of Coordination Dynamics is introduced, including the main concepts of control parameters and collective variables, theoretical modeling, novel experimental paradigms, and cardinal empirical findings. Basic conceptual and methodological issues for the design and implementation of coordination experiments in the context of neuroimaging are discussed. The paper concludes with a presentation of neuroimaging findings central to understanding the neural basis of coordination and addresses their relevance for the sport sciences. The latter include but are not restricted to learning and practice-related issues, the role of mental imagery, and the recovery of function following brain injury. PMID:18602998

  11. Modified heliocentric coordinates for particle dynamics

    NASA Astrophysics Data System (ADS)

    Smith, F. T.

    1980-10-01

    A modified heliocentric coordinate system is found for the dynamics of n + 1 particles that is barycentric, diagonalizes the kinetic energy, and is symmetric in n of the particles. The n planetary vectors are based on Radau's canonical point between the center of mass and the heliocenter. These coordinates are especially valuable for describing centrosymmetric molecular fragments ABn, and useful also for the mass polarization in atoms.

  12. The coordination dynamics of social neuromarkers.

    PubMed

    Tognoli, Emmanuelle; Kelso, J A Scott

    2015-01-01

    Social behavior is a complex integrative function that entails many aspects of the brain's sensory, cognitive, emotional and movement capacities. Its neural processes are seldom simultaneous but occur according to precise spatiotemporal choreographies, manifested by the coordination of their oscillations within and between brains. Methods with good temporal resolution can help to identify so-called "neuromarkers" of social function and aid in disentangling the dynamical architecture of social brains. In our ongoing research, we have used dual-electroencephalography (EEG) to study neuromarker dynamics during synchronic interactions in which pairs of subjects coordinate behavior spontaneously and intentionally (social coordination) and during diachronic transactions that require subjects to perceive or behave in turn (action observation, delayed imitation). In this paper, after outlining our dynamical approach to the neurophysiological basis of social behavior, we examine commonalities and differences in the neuromarkers that are recruited for both kinds of tasks. We find the neuromarker landscape to be task-specific: synchronic paradigms of social coordination reveal medial mu, alpha and the phi complex as contributing neuromarkers. Diachronic tasks recruit alpha as well, in addition to lateral mu rhythms and the newly discovered nu and kappa rhythms whose functional significance is still unclear. Social coordination, observation, and delayed imitation share commonality of context: in each of our experiments, subjects exchanged information through visual perception and moved in similar ways. Nonetheless, there was little overlap between their neuromarkers, a result that hints strongly of task-specific neural mechanisms for social behavior. The only neuromarker that transcended both synchronic and diachronic social behaviors was the ubiquitous alpha rhythm, which appears to be a key signature of visually-mediated social behaviors. The present paper is both an entry

  13. The coordination dynamics of social neuromarkers

    PubMed Central

    Tognoli, Emmanuelle; Kelso, J. A. Scott

    2015-01-01

    Social behavior is a complex integrative function that entails many aspects of the brain’s sensory, cognitive, emotional and movement capacities. Its neural processes are seldom simultaneous but occur according to precise spatiotemporal choreographies, manifested by the coordination of their oscillations within and between brains. Methods with good temporal resolution can help to identify so-called “neuromarkers” of social function and aid in disentangling the dynamical architecture of social brains. In our ongoing research, we have used dual-electroencephalography (EEG) to study neuromarker dynamics during synchronic interactions in which pairs of subjects coordinate behavior spontaneously and intentionally (social coordination) and during diachronic transactions that require subjects to perceive or behave in turn (action observation, delayed imitation). In this paper, after outlining our dynamical approach to the neurophysiological basis of social behavior, we examine commonalities and differences in the neuromarkers that are recruited for both kinds of tasks. We find the neuromarker landscape to be task-specific: synchronic paradigms of social coordination reveal medial mu, alpha and the phi complex as contributing neuromarkers. Diachronic tasks recruit alpha as well, in addition to lateral mu rhythms and the newly discovered nu and kappa rhythms whose functional significance is still unclear. Social coordination, observation, and delayed imitation share commonality of context: in each of our experiments, subjects exchanged information through visual perception and moved in similar ways. Nonetheless, there was little overlap between their neuromarkers, a result that hints strongly of task-specific neural mechanisms for social behavior. The only neuromarker that transcended both synchronic and diachronic social behaviors was the ubiquitous alpha rhythm, which appears to be a key signature of visually-mediated social behaviors. The present paper is both an

  14. A dynamic human motion: coordination analysis.

    PubMed

    Pchelkin, Stepan; Shiriaev, Anton S; Freidovich, Leonid B; Mettin, Uwe; Gusev, Sergei V; Kwon, Woong; Paramonov, Leonid

    2015-02-01

    This article is concerned with the generic structure of the motion coordination system resulting from the application of the method of virtual holonomic constraints (VHCs) to the problem of the generation and robust execution of a dynamic humanlike motion by a humanoid robot. The motion coordination developed using VHCs is based on a motion generator equation, which is a scalar nonlinear differential equation of second order. It can be considered equivalent in function to a central pattern generator in living organisms. The relative time evolution of the degrees of freedom of a humanoid robot during a typical motion are specified by a set of coordination functions that uniquely define the overall pattern of the motion. This is comparable to a hypothesis on the existence of motion patterns in biomechanics. A robust control is derived based on a transverse linearization along the configuration manifold defined by the coordination functions. It is shown that the derived coordination and control architecture possesses excellent robustness properties. The analysis is performed on an example of a real human motion recorded in test experiments.

  15. COORDINATION DYNAMICS OF THE COMPLEMENTARY NATURE

    PubMed Central

    Engstrøm, David A.; Scott Kelso, JA

    2009-01-01

    Summary Niels Bohr’s maxim contraria sunt complementa indicated his strong suspicion that the complementarity interpretation of quantum mechanics might someday be expanded into a generalized principle. It now appears that such a principle has been found in metastability which appears at the scale of living things. Metastability has been proposed as a principle of brain~behavior, and is captured in the extended or ‘broken-symmetry’ version of the HKB model of coordination dynamics. The metastable regime of coordination dynamics reconciles the tendency of specialized brain regions to express autonomy (segregation) and their simultaneous tendency to work together as a synergetic whole (integration). There is growing evidence from recent studies in the brain and behavioral sciences that the complementary nature of integrating and segregating tendencies is essential to the way human brain~minds work. PMID:20634938

  16. CODA: Coordinated Observations of Dynamics in Aurora

    NASA Technical Reports Server (NTRS)

    Larsen, M. F.

    2003-01-01

    The grant funds were provided to carry out chemical tracer wind and turbulence measurements in the mesosphere and lower thermosphere as part of the Coordinated Observations of Dynamics in Aurora (CODA) experiment for which Dr. Andy Christensen of the Aerospace Corp. was the Principal Investigator. Clemson University was a co-investigator institution on the project and was tasked with designing, building, and testing a total of four chemical tracer release payloads which were used to release trimethyl aluminum (TMA) to measure the winds and turbulent diffusion. All four payloads were flown from the rocket range at Poker Flat, Alaska, in support of instrumented payloads flown from the same location. The CODA experiment was designed to investigate the changes in the chemical composition in the lower thermosphere during an auroral substorm event. In particular, the objective was to determine the relative importance of two competing mechanisms. The first mechanism is associated with the advection of air from the polar cap into the auroral oval. A flow in that direction is typical in the postmidnight sector of the oval. As the air moves from the region of negligible forcing in the polar cap to the region of strong forcing and heating in the oval, changes in the composition are expected to occur. Alternatively, enhanced local mixing will also cause such changes. Since the auroral forcing accelerates the neutral winds in the lower E region, but not at lower altitudes, the forcing results in large shears that can be large enough to be unstable in the Richardson number sense. The unstable shears are expected to generate turbulence and therefore enhanced mixing. Such mixing will also create composition changes similar to what is observed. In the CODA experiment an instrumented payload designed and built by the Aerospace Corporation was used to measure the composition and plasma parameters needed to define the auroral forcing. In addition, three chemical tracer payloads were

  17. Highly accurate articulated coordinate measuring machine

    DOEpatents

    Bieg, Lothar F.; Jokiel, Jr., Bernhard; Ensz, Mark T.; Watson, Robert D.

    2003-12-30

    Disclosed is a highly accurate articulated coordinate measuring machine, comprising a revolute joint, comprising a circular encoder wheel, having an axis of rotation; a plurality of marks disposed around at least a portion of the circumference of the encoder wheel; bearing means for supporting the encoder wheel, while permitting free rotation of the encoder wheel about the wheel's axis of rotation; and a sensor, rigidly attached to the bearing means, for detecting the motion of at least some of the marks as the encoder wheel rotates; a probe arm, having a proximal end rigidly attached to the encoder wheel, and having a distal end with a probe tip attached thereto; and coordinate processing means, operatively connected to the sensor, for converting the output of the sensor into a set of cylindrical coordinates representing the position of the probe tip relative to a reference cylindrical coordinate system.

  18. Internal Coordinate Molecular Dynamics: A Foundation for Multiscale Dynamics

    PubMed Central

    2015-01-01

    Internal coordinates such as bond lengths, bond angles, and torsion angles (BAT) are natural coordinates for describing a bonded molecular system. However, the molecular dynamics (MD) simulation methods that are widely used for proteins, DNA, and polymers are based on Cartesian coordinates owing to the mathematical simplicity of the equations of motion. However, constraints are often needed with Cartesian MD simulations to enhance the conformational sampling. This makes the equations of motion in the Cartesian coordinates differential-algebraic, which adversely impacts the complexity and the robustness of the simulations. On the other hand, constraints can be easily placed in BAT coordinates by removing the degrees of freedom that need to be constrained. Thus, the internal coordinate MD (ICMD) offers an attractive alternative to Cartesian coordinate MD for developing multiscale MD method. The torsional MD method is a special adaptation of the ICMD method, where all the bond lengths and bond angles are kept rigid. The advantages of ICMD simulation methods are the longer time step size afforded by freezing high frequency degrees of freedom and performing a conformational search in the more important low frequency torsional degrees of freedom. However, the advancements in the ICMD simulations have been slow and stifled by long-standing mathematical bottlenecks. In this review, we summarize the recent mathematical advancements we have made based on spatial operator algebra, in developing a robust long time scale ICMD simulation toolkit useful for various applications. We also present the applications of ICMD simulations to study conformational changes in proteins and protein structure refinement. We review the advantages of the ICMD simulations over the Cartesian simulations when used with enhanced sampling methods and project the future use of ICMD simulations in protein dynamics. PMID:25517406

  19. Dynamic similarity promotes interpersonal coordination in joint action

    PubMed Central

    Słowiński, Piotr; Zhai, Chao; Alderisio, Francesco; Salesse, Robin; Gueugnon, Mathieu; Marin, Ludovic; Bardy, Benoit G.; di Bernardo, Mario; Tsaneva-Atanasova, Krasimira

    2016-01-01

    Human movement has been studied for decades, and dynamic laws of motion that are common to all humans have been derived. Yet, every individual moves differently from everyone else (faster/slower, harder/smoother, etc.). We propose here an index of such variability, namely an individual motor signature (IMS) able to capture the subtle differences in the way each of us moves. We show that the IMS of a person is time-invariant and that it significantly differs from those of other individuals. This allows us to quantify the dynamic similarity, a measure of rapport between dynamics of different individuals' movements, and demonstrate that it facilitates coordination during interaction. We use our measure to confirm a key prediction of the theory of similarity that coordination between two individuals performing a joint-action task is higher if their motions share similar dynamic features. Furthermore, we use a virtual avatar driven by an interactive cognitive architecture based on feedback control theory to explore the effects of different kinematic features of the avatar motion on coordination with human players. PMID:27009178

  20. Dynamic similarity promotes interpersonal coordination in joint action.

    PubMed

    Słowiński, Piotr; Zhai, Chao; Alderisio, Francesco; Salesse, Robin; Gueugnon, Mathieu; Marin, Ludovic; Bardy, Benoit G; di Bernardo, Mario; Tsaneva-Atanasova, Krasimira

    2016-03-01

    Human movement has been studied for decades, and dynamic laws of motion that are common to all humans have been derived. Yet, every individual moves differently from everyone else (faster/slower, harder/smoother, etc.). We propose here an index of such variability, namely an individual motor signature (IMS) able to capture the subtle differences in the way each of us moves. We show that the IMS of a person is time-invariant and that it significantly differs from those of other individuals. This allows us to quantify the dynamic similarity, a measure of rapport between dynamics of different individuals' movements, and demonstrate that it facilitates coordination during interaction. We use our measure to confirm a key prediction of the theory of similarity that coordination between two individuals performing a joint-action task is higher if their motions share similar dynamic features. Furthermore, we use a virtual avatar driven by an interactive cognitive architecture based on feedback control theory to explore the effects of different kinematic features of the avatar motion on coordination with human players. PMID:27009178

  1. Vision guided automatic measuring in coordinate metrology

    NASA Astrophysics Data System (ADS)

    Qin, Yuhong; Wang, Lei; Xie, Lusheng; Huang, Yuanqing

    2008-12-01

    A novel automatically measuring planning method in coordinate metrology based on computer vision is presented in this paper. An active stereo vision system is established by attaching a CCD camera to the mechanical probe of the coordinate measuring machine (CMM). Through the movement of the probe of the CMM, as well as the camera, 3D edge characters of the object can be acquired, which are used as clues for automatically coordinate measuring. A multi-baseline matching method is presented to overcome the ambiguity in stereo matching, and a quadratic interpolating is used in sub pixel matching to get continuous depth image. The matching is only done on character edges in images, so it is much faster and more robust. Two methods of measuring path planning are put forward, in one way, a 2D characteristic edge image which are often stand for rapidly changes in depth or curvature of object surface can be acquired by projecting 3D edge characters to a scanning plane, and then the sampling points of mechanical probe are selected depending on the edge image. In the other way, surface patches are fitted to these 3D edges, and the sampling grid is determined by the type and area of every patch. Using these techniques, a highly automated high-speed, high-precision, 3-D coordinate acquisition system based on multiple-sensor integration can be developed. It has potential applications in manufacturing problems as metrology, inspection, and reverse engineering.

  2. The coordination dynamics of mobile conjugate reinforcement.

    PubMed

    Kelso, J A Scott; Fuchs, Armin

    2016-02-01

    What we know about infant learning and memory is founded largely on systematic studies by the late Carolyn Rovee-Collier (1942-2014) and her associates of a phenomenon called mobile conjugate reinforcement. Experiments show that when a ribbon is attached from a 3-month-old infant's foot to a mobile suspended overhead the baby quickly realizes it can make the mobile move. The mobile, which offers interesting sights and sounds, responds conjugately to the baby's vigorous kicks which increase in rate by a factor of 3-4. In this paper, using the concepts, methods and tools of coordination dynamics, we present a theoretical model which reproduces the experimental observations of Rovee-Collier and others and predicts a number of additional features that can be experimentally tested. The model is a dynamical system consisting of three equations, one for the baby's leg movements, one for the jiggling motion of the mobile and one for the functional coupling between the two. A key mechanism in the model is positive feedback which is shown to depend sensitively on bifurcation parameters related to the infant's level of attention and inertial properties of the mobile. The implications of our model for the dynamical (and developmental) origins of agency are discussed. PMID:26759265

  3. Conservative-coordinate transformations for atmospheric measurements

    NASA Technical Reports Server (NTRS)

    Schoeberl, M. R.; Lait, L. R.

    1992-01-01

    This lecture describes a technique by which atmospheric measurements of trace species with medium to long lifetimes can be 'coincidentally' compared and validated even though measurements are taken at different locations and different times In other words, the method, under suitable counditions, can remove a large amount of the natural meteorological variability. The technique involves the use of quasi-Lagrangian or conservative coordinates - air parcel tags which are invariant or nearly invariant under the motion of the parcel. The technique is called 'reconstruction', since measurements taken at one location can be reconstructed at different locations. In order to do this, the data are transformed into the conservative coordinates and accumulated. Within the conservative reference frame, much of the meteorological variability is removed. Once enough data are obtained within the system, the observations can be tranformed back into physical space at any location and compared with other measurements. The method by which the trace species data are obtained makes no difference; satellite, balloon, rocket, aircraft and ground-based data all become equivalent and can be intercompared. The conservative-coordinate system not only allows for intercomparison of data, but shows how data can be taken in such a way as to maximize the physical scope of the information. In other words, the method automatically suggests when conditions might be suitable to obtain information with different environmental situations. It also allows for the forecast of constituent fields using only the meteorological forecasts and limited observational data.

  4. A heart for interaction: Shared physiological dynamics and behavioral coordination in a collective, creative construction task.

    PubMed

    Fusaroli, Riccardo; Bjørndahl, Johanne S; Roepstorff, Andreas; Tylén, Kristian

    2016-09-01

    Interpersonally shared physiological dynamics are increasingly argued to underlie rapport, empathy, and even team performance. Inspired by the model of interpersonal synergy, we critically investigate the presence, temporal development, possible mechanisms and impact of shared interpersonal heart rate (HR) dynamics during individual and collective creative LEGO® construction tasks. In Study 1 we show how shared HR dynamics are driven by a plurality of sources, including task constraints and behavioral coordination. Generally, shared HR dynamics are more prevalent in individual trials (involving participants doing the same things) than in collective ones (involving participants taking turns and performing complementary actions). However, when contrasted against virtual pairs, collective trials display more stable shared HR dynamics suggesting that online social interaction plays an important role. Furthermore, in contrast to individual trials, shared HR dynamics are found to increase across collective trials. Study 2 investigates which aspects of social interaction might drive these effects. We show that shared HR dynamics are statistically predicted by interpersonal speech and building coordination. In Study 3, we explore the relation between HR dynamics, behavioral coordination, and self-reported measures of rapport and group competence. Although behavioral coordination predicts rapport and group competence, shared HR dynamics do not. Although shared physiological dynamics were reliably observed in our study, our results warrant not to consider HR dynamics a general driving mechanism of social coordination. Behavioral coordination-on the other hand-seems to be more informative of both shared physiological dynamics and collective experience. (PsycINFO Database Record PMID:26962844

  5. A heart for interaction: Shared physiological dynamics and behavioral coordination in a collective, creative construction task.

    PubMed

    Fusaroli, Riccardo; Bjørndahl, Johanne S; Roepstorff, Andreas; Tylén, Kristian

    2016-09-01

    Interpersonally shared physiological dynamics are increasingly argued to underlie rapport, empathy, and even team performance. Inspired by the model of interpersonal synergy, we critically investigate the presence, temporal development, possible mechanisms and impact of shared interpersonal heart rate (HR) dynamics during individual and collective creative LEGO® construction tasks. In Study 1 we show how shared HR dynamics are driven by a plurality of sources, including task constraints and behavioral coordination. Generally, shared HR dynamics are more prevalent in individual trials (involving participants doing the same things) than in collective ones (involving participants taking turns and performing complementary actions). However, when contrasted against virtual pairs, collective trials display more stable shared HR dynamics suggesting that online social interaction plays an important role. Furthermore, in contrast to individual trials, shared HR dynamics are found to increase across collective trials. Study 2 investigates which aspects of social interaction might drive these effects. We show that shared HR dynamics are statistically predicted by interpersonal speech and building coordination. In Study 3, we explore the relation between HR dynamics, behavioral coordination, and self-reported measures of rapport and group competence. Although behavioral coordination predicts rapport and group competence, shared HR dynamics do not. Although shared physiological dynamics were reliably observed in our study, our results warrant not to consider HR dynamics a general driving mechanism of social coordination. Behavioral coordination-on the other hand-seems to be more informative of both shared physiological dynamics and collective experience. (PsycINFO Database Record

  6. Measurement, coordination, and the relativized a priori

    NASA Astrophysics Data System (ADS)

    Padovani, Flavia

    2015-11-01

    The problem of measurement is a central issue in the epistemology and methodology of the physical sciences. In recent literature on scientific representation, large emphasis has been put on the "constitutive role" played by measurement procedures as forms of representation. Despite its importance, this issue hardly finds any mention in writings on constitutive principles, viz. in Michael Friedman's account of relativized a priori principles. This issue, instead, was at the heart of Reichenbach's analysis of coordinating principles that has inspired Friedman's interpretation. This paper suggests that these procedures should have a part in an account of constitutive principles of science, and that they could be interpreted following the intuition originally present (but ultimately not fully developed) in Reichenbach's early work.

  7. Lithographic tool dynamic coordinate calibration for CDU improvement

    NASA Astrophysics Data System (ADS)

    Yang, Zhiyong; Mao, Fanglin; Bourov, Anatoly; Cheng, Jianrui; He, Le

    2012-03-01

    In lithographic scanner, many different physical factors could impact to image quality and CD uniformity. In optical systems, the pupil filling quality (source shape), wavefront error and stray light can decrease the intensity contrast and shrink the process window. In mechanical domain, the vibration and scanning synchronization error have the similar effect to imaging process. Imaging in scanner is a dynamic exposure process and in this process, aerial image should keep the same relative position to the wafer. It requests the lithographic tool must have a very stable mechanical frame and very good motion control performance. In addition, the wafer stage, reticle stage's coordinate and projection lens' grid should be matched exactly, include the scanning direction and velocity ratio. The tool's alignment system can calibrate the statistic coordinate for overlay, but it cannot calibrate the dynamic coordinate in scanning direction very well because projection lens' grid has a small asymmetric signiture. This systematic error should be calibrated for CDU improvement. An imaging model considering the motion blurring is represented in this paper and based on this model, the dynamic coordinate's error could be analyzed. Furthermore, exposure method can be used to calibrate the dynamic coordinate and improve the CD uniformity. Exposure latitude will be used to check and calibrate the lithographic tool's dynamic coordinate. We designed a special calibration process to obtain the best dynamic coordinate setting for scanner. In this process, some tool's coordinate parameters (scanning skew and scale) have been changed for every field to obtain the multi-dimensions' exposure information. Exposure window can be represented from this result, and in this exposure window, the best dynamic coordinate setting could be found. After the dynamic coordinate calibrated, the CDU is improved.

  8. Specimen coordinate automated measuring machine/fiducial automated measuring machine

    DOEpatents

    Hedglen, Robert E.; Jacket, Howard S.; Schwartz, Allan I.

    1991-01-01

    The Specimen coordinate Automated Measuring Machine (SCAMM) and the Fiducial Automated Measuring Machine (FAMM) is a computer controlled metrology system capable of measuring length, width, and thickness, and of locating fiducial marks. SCAMM and FAMM have many similarities in their designs, and they can be converted from one to the other without taking them out of the hot cell. Both have means for: supporting a plurality of samples and a standard; controlling the movement of the samples in the +/- X and Y directions; determining the coordinates of the sample; compensating for temperature effects; and verifying the accuracy of the measurements and repeating as necessary. SCAMM and FAMM are designed to be used in hot cells.

  9. Dynamical methods for evaluating the time-dependent unfolding of social coordination in children with autism

    PubMed Central

    Fitzpatrick, Paula; Diorio, Rachel; Richardson, Michael J.; Schmidt, R. C.

    2013-01-01

    Children with Autism Spectrum Disorder (ASD) suffer from numerous impairments in social interaction that affect both their mental and bodily coordination with others. We explored here whether interpersonal motor coordination may be an important key for understanding the profound social problems of children with ASD. We employed a set of experimental techniques to evaluate not only traditional cognitive measures of social competence but also the dynamical structure of social coordination by using dynamical measures of social motor coordination and analyzing the time series records of behavior. Preliminary findings suggest that children with ASD were equivalent to typically developing children on many social performance outcome measures. However, significant relationships were found between cognitive social measures (e.g., intentionality) and dynamical social motor measures. In addition, we found that more perceptually-based measures of social coordination were not associated with social motor coordination. These findings suggest that social coordination may not be a unitary construct and point to the promise of this multi-method and process-oriented approach to analyzing social coordination as an important pathway for understanding ASD-specific social deficits. PMID:23580133

  10. Framework for coordination of activities in dynamic situations

    NASA Astrophysics Data System (ADS)

    Franke, Jörn; Charoy, François; El Khoury, Paul

    2013-02-01

    Recent disasters, such as Hurricane Katrina in 2005, have shown several issues for the coordination of human activities in these dynamic situations. Contemporary tools for the coordination used in the disaster response, such as e-mail, Whiteboards or phones, only allow for unstructured coordination, which can cause coordination problems. Hence, we discuss about the current information systems for coordinating the activities in a structured manner and identify their weaknesses in the context of a process modelling effort conducted together with experienced disaster managers. Afterwards, we propose a framework for coordination of activities in dynamic situations. The framework presented in this paper has been implemented as an extension to an open collaboration service. This shows how it can be used in the context of other tools required for disaster response management, such as maps, pictures or videos of the situation. The work described here is the foundation for enabling inter-organisational coordination of activities relevant in other domains, e.g. enterprise support processes, production processes or distributed software development projects. Furthermore, comments by disaster managers show that the concepts are relevant for their work. The expected impact is a more effective and efficient coordination of human activities in dynamic situations by structuring what needs to be coordinated.

  11. Higher-Order Synaptic Interactions Coordinate Dynamics in Recurrent Networks

    PubMed Central

    Chambers, Brendan; MacLean, Jason N.

    2016-01-01

    Linking synaptic connectivity to dynamics is key to understanding information processing in neocortex. Circuit dynamics emerge from complex interactions of interconnected neurons, necessitating that links between connectivity and dynamics be evaluated at the network level. Here we map propagating activity in large neuronal ensembles from mouse neocortex and compare it to a recurrent network model, where connectivity can be precisely measured and manipulated. We find that a dynamical feature dominates statistical descriptions of propagating activity for both neocortex and the model: convergent clusters comprised of fan-in triangle motifs, where two input neurons are themselves connected. Fan-in triangles coordinate the timing of presynaptic inputs during ongoing activity to effectively generate postsynaptic spiking. As a result, paradoxically, fan-in triangles dominate the statistics of spike propagation even in randomly connected recurrent networks. Interplay between higher-order synaptic connectivity and the integrative properties of neurons constrains the structure of network dynamics and shapes the routing of information in neocortex. PMID:27542093

  12. Higher-Order Synaptic Interactions Coordinate Dynamics in Recurrent Networks.

    PubMed

    Chambers, Brendan; MacLean, Jason N

    2016-08-01

    Linking synaptic connectivity to dynamics is key to understanding information processing in neocortex. Circuit dynamics emerge from complex interactions of interconnected neurons, necessitating that links between connectivity and dynamics be evaluated at the network level. Here we map propagating activity in large neuronal ensembles from mouse neocortex and compare it to a recurrent network model, where connectivity can be precisely measured and manipulated. We find that a dynamical feature dominates statistical descriptions of propagating activity for both neocortex and the model: convergent clusters comprised of fan-in triangle motifs, where two input neurons are themselves connected. Fan-in triangles coordinate the timing of presynaptic inputs during ongoing activity to effectively generate postsynaptic spiking. As a result, paradoxically, fan-in triangles dominate the statistics of spike propagation even in randomly connected recurrent networks. Interplay between higher-order synaptic connectivity and the integrative properties of neurons constrains the structure of network dynamics and shapes the routing of information in neocortex. PMID:27542093

  13. Method to describe stochastic dynamics using an optimal coordinate.

    PubMed

    Krivov, Sergei V

    2013-12-01

    A general method to describe the stochastic dynamics of Markov processes is suggested. The method aims to solve three related problems: the determination of an optimal coordinate for the description of stochastic dynamics; the reconstruction of time from an ensemble of stochastic trajectories; and the decomposition of stationary stochastic dynamics into eigenmodes which do not decay exponentially with time. The problems are solved by introducing additive eigenvectors which are transformed by a stochastic matrix in a simple way - every component is translated by a constant distance. Such solutions have peculiar properties. For example, an optimal coordinate for stochastic dynamics with detailed balance is a multivalued function. An optimal coordinate for a random walk on a line corresponds to the conventional eigenvector of the one-dimensional Dirac equation. The equation for the optimal coordinate in a slowly varying potential reduces to the Hamilton-Jacobi equation for the action function. PMID:24483410

  14. Challenges for the understanding of the dynamics of social coordination

    PubMed Central

    Lagarde, Julien

    2013-01-01

    The way people interact can be examined by looking at the way they move relative to each other. Seeking the principles behind those interactions have consequences potentially related to any type of interpersonal function, far beyond the so-called “motor” processes typically associated with the study of movements, be it perceptive, cognitive, affective, pragmatic, or epistemic. Here, we present the way the framework of coordination dynamics define and addresses the interactive actions in a dyad. We first introduce the basics of pattern formation as the roots of the theoretical approach of coordination dynamics, and then the way this framework may contribute to establish a solution to classify behaviors. Thereafter we review promising empirical results on the dynamics of interpersonal coordination, and finally discuss were to go next to decipher the way the coordination between two people and the way each individual contribute may be disentangled. PMID:24130526

  15. Dynamic coordination of a self-reconfigurable manipulator system

    NASA Technical Reports Server (NTRS)

    Kim, Sungbok; Lee, Sukhan

    1991-01-01

    The authors present the dynamic coordination of a self-reconfigurable manipulator system capable of changing its mechanical structure according to given task requirements. The self-reconfiguration is achieved by reconfiguring the topology of a dual-arm system through serial, parallel, and bracing structures. Particular emphasis is placed on the dynamic coordination of two arms having three different dual-arm topologies. The authors develop the Cartesian space dynamic models of a dual-arm system of three dual-arm topologies and derive the kinematic and dynamic constraints imposed on two arms in cooperation. Dual-arm dynamic manipulabilities are defined to quantify the dynamic performance of three dual-arm topologies in terms of the efficiency of generating Cartesian accelerations. A methodology of selecting serial, parallel, and bracing structures based on dual-arm dynamic manipulabilities is provided.

  16. Combination of a vision system and a coordinate measuring machine for rapid coordinate metrology

    NASA Astrophysics Data System (ADS)

    Qu, Yufu; Pu, Zhaobang; Liu, Guodong

    2002-09-01

    This paper presents a novel methodology that integrates a vision system and a coordinate measuring machine for rapid coordinate metrology. Rapid acquisition of coordinate data from parts having tiny dimension, complex geometry and soft or fragile material has many applications. Typical examples include Large Scale Integrated circuit, glass or plastic part measurement, and reverse engineering in rapid product design and realization. In this paper, a novel approach to a measuring methodology for a vision integrated coordinate measuring system is developed and demonstrated. The vision coordinate measuring system is characterized by an integrated use of a high precision coordinate measuring machine (CMM), a vision system, advanced computational software, and the associated electronics. The vision system includes a charge-coupled device (CCD) camera, a self-adapt brightness power, and a graphics workstation with an image processing board. The vision system along with intelligent feature recognition and auto-focus algorithms provides the feature point space coordinate of global part profile after the system has been calibrated. The measured data may be fitted to geometry element of part profile. The obtained results are subsequently used to compute parameters consist of curvature radius, distance, shape error and surface reconstruction. By integrating the vision system with the CMM, a highly automated, high speed, 3D coordinate acquisition system is developed. It has potential applications in a whole spectrum of manufacturing problems with a major impact on metrology, inspection, and reverse engineering.

  17. Virtual Partner Interaction (VPI): Exploring Novel Behaviors via Coordination Dynamics

    PubMed Central

    Kelso, J. A. Scott; de Guzman, Gonzalo C.; Reveley, Colin; Tognoli, Emmanuelle

    2009-01-01

    Inspired by the dynamic clamp of cellular neuroscience, this paper introduces VPI—Virtual Partner Interaction—a coupled dynamical system for studying real time interaction between a human and a machine. In this proof of concept study, human subjects coordinate hand movements with a virtual partner, an avatar of a hand whose movements are driven by a computerized version of the Haken-Kelso-Bunz (HKB) equations that have been shown to govern basic forms of human coordination. As a surrogate system for human social coordination, VPI allows one to examine regions of the parameter space not typically explored during live interactions. A number of novel behaviors never previously observed are uncovered and accounted for. Having its basis in an empirically derived theory of human coordination, VPI offers a principled approach to human-machine interaction and opens up new ways to understand how humans interact with human-like machines including identification of underlying neural mechanisms. PMID:19492044

  18. Large-deformation modal coordinates for nonrigid vehicle dynamics

    NASA Technical Reports Server (NTRS)

    Likins, P. W.; Fleischer, G. E.

    1972-01-01

    The derivation of minimum-dimension sets of discrete-coordinate and hybrid-coordinate equations of motion of a system consisting of an arbitrary number of hinge-connected rigid bodies assembled in tree topology is presented. These equations are useful for the simulation of dynamical systems that can be idealized as tree-like arrangements of substructures, with each substructure consisting of either a rigid body or a collection of elastically interconnected rigid bodies restricted to small relative rotations at each connection. Thus, some of the substructures represent elastic bodies subjected to small strains or local deformations, but possibly large gross deformations, in the hybrid formulation, distributed coordinates referred to herein as large-deformation modal coordinates, are used for the deformations of these substructures. The equations are in a form suitable for incorporation into one or more computer programs to be used as multipurpose tools in the simulation of spacecraft and other complex electromechanical systems.

  19. The Teaching of Polar Coordinates with Dynamic Mathematics Software

    ERIC Educational Resources Information Center

    Zengin, Yilmaz; Tatar, Enver

    2015-01-01

    The purpose of this study was to determine the effects of dynamic mathematics software on the achievement of pre-service mathematics teachers in the topic of polar coordinates and to solicit their opinions about computer-assisted instruction. The study was conducted for 11 weeks with 33 pre-service teachers in the Department of Mathematics…

  20. Coupling Dynamics Interlip Coordination in Lower Lip Load Compensation

    ERIC Educational Resources Information Center

    van Lieshout, Pascal; Neufeld, Chris

    2014-01-01

    Purpose: To study the effects of lower lip loading on lower and upper lip movements and their coordination to test predictions on coupling dynamics derived from studies in limb control. Method: Movement data were acquired using electromagnetic midsagittal articulography under 4 conditions: (a) without restrictions, serving as a baseline; (b) with…

  1. Functional coordination of muscles underlying changes in behavioural dynamics.

    PubMed

    Vernooij, Carlijn A; Rao, Guillaume; Perdikis, Dionysios; Huys, Raoul; Jirsa, Viktor K; Temprado, Jean-Jacques

    2016-01-01

    The dynamical systems approach addresses Bernstein's degrees of freedom problem by assuming that the neuro-musculo-skeletal system transiently assembles and dismantles its components into functional units (or synergies) to meet task demands. Strikingly, little is known from a dynamical point of view about the functioning of the muscular sub-system in this process. To investigate the interaction between the dynamical organisation at muscular and behavioural levels, we searched for specific signatures of a phase transition in muscular coordination when a transition is displayed at the behavioural level. Our results provide evidence that, during Fitts' task when behaviour switches to a different dynamical regime, muscular activation displays typical signatures of a phase transition; a reorganisation in muscular coordination patterns accompanied by a peak in the variability of muscle activation. This suggests that consistent changes occur in coordination processes across the different levels of description (i.e., behaviour and muscles). Specifically, in Fitts' task, target size acts as a control parameter that induces a destabilisation and a reorganisation of coordination patterns at different levels of the neuro-musculo-skeletal system. PMID:27282349

  2. Functional coordination of muscles underlying changes in behavioural dynamics

    PubMed Central

    Vernooij, Carlijn A.; Rao, Guillaume; Perdikis, Dionysios; Huys, Raoul; Jirsa, Viktor K.; Temprado, Jean-Jacques

    2016-01-01

    The dynamical systems approach addresses Bernstein’s degrees of freedom problem by assuming that the neuro-musculo-skeletal system transiently assembles and dismantles its components into functional units (or synergies) to meet task demands. Strikingly, little is known from a dynamical point of view about the functioning of the muscular sub-system in this process. To investigate the interaction between the dynamical organisation at muscular and behavioural levels, we searched for specific signatures of a phase transition in muscular coordination when a transition is displayed at the behavioural level. Our results provide evidence that, during Fitts’ task when behaviour switches to a different dynamical regime, muscular activation displays typical signatures of a phase transition; a reorganisation in muscular coordination patterns accompanied by a peak in the variability of muscle activation. This suggests that consistent changes occur in coordination processes across the different levels of description (i.e., behaviour and muscles). Specifically, in Fitts’ task, target size acts as a control parameter that induces a destabilisation and a reorganisation of coordination patterns at different levels of the neuro-musculo-skeletal system. PMID:27282349

  3. Automatic ball bar for a coordinate measuring machine

    DOEpatents

    Jostlein, H.

    1997-07-15

    An automatic ball bar for a coordinate measuring machine determines the accuracy of a coordinate measuring machine having at least one servo drive. The apparatus comprises a first and second gauge ball connected by a telescoping rigid member. The rigid member includes a switch such that inward radial movement of the second gauge ball relative to the first gauge ball causes activation of the switch. The first gauge ball is secured in a first magnetic socket assembly in order to maintain the first gauge ball at a fixed location with respect to the coordinate measuring machine. A second magnetic socket assembly secures the second gauge ball to the arm or probe holder of the coordinate measuring machine. The second gauge ball is then directed by the coordinate measuring machine to move radially inward from a point just beyond the length of the ball bar until the switch is activated. Upon switch activation, the position of the coordinate measuring machine is determined and compared to known ball bar length such that the accuracy of the coordinate measuring machine can be determined. 5 figs.

  4. Automatic ball bar for a coordinate measuring machine

    DOEpatents

    Jostlein, Hans

    1997-01-01

    An automatic ball bar for a coordinate measuring machine determines the accuracy of a coordinate measuring machine having at least one servo drive. The apparatus comprises a first and second gauge ball connected by a telescoping rigid member. The rigid member includes a switch such that inward radial movement of the second gauge ball relative to the first gauge ball causes activation of the switch. The first gauge ball is secured in a first magnetic socket assembly in order to maintain the first gauge ball at a fixed location with respect to the coordinate measuring machine. A second magnetic socket assembly secures the second gauge ball to the arm or probe holder of the coordinate measuring machine. The second gauge ball is then directed by the coordinate measuring machine to move radially inward from a point just beyond the length of the ball bar until the switch is activated. Upon switch activation, the position of the coordinate measuring machine is determined and compared to known ball bar length such that the accuracy of the coordinate measuring machine can be determined.

  5. Rowing Crew Coordination Dynamics at Increasing Stroke Rates

    PubMed Central

    2015-01-01

    In rowing, perfect synchronisation is important for optimal performance of a crew. Remarkably, a recent study on ergometers demonstrated that antiphase crew coordination might be mechanically more efficient by reducing the power lost to within-cycle velocity fluctuations of the boat. However, coupled oscillator dynamics predict the stability of the coordination to decrease with increasing stroke rate, which in case of antiphase may eventually yield breakdowns to in-phase. Therefore, this study examined the effects of increasing stroke rate on in- and antiphase crew coordination in rowing dyads. Eleven experienced dyads rowed on two mechanically coupled ergometers on slides, which allowed the ergometer system to move back and forth as one ‘boat’. The dyads performed a ramp trial in both in- and antiphase pattern, in which stroke rates gradually increased from 30 strokes per minute (spm) to as fast as possible in steps of 2 spm. Kinematics of rowers, handles and ergometers were captured. Two dyads showed a breakdown of antiphase into in-phase coordination at the first stroke rate of the ramp trial. The other nine dyads reached between 34–42 spm in antiphase but achieved higher rates in in-phase. As expected, the coordinative accuracy in antiphase was worse than in in-phase crew coordination, while, somewhat surprisingly, the coordinative variability did not differ between the patterns. Whereas crew coordination did not substantially deteriorate with increasing stroke rate, stroke rate did affect the velocity fluctuations of the ergometers: fluctuations were clearly larger in the in-phase pattern than in the antiphase pattern, and this difference significantly increased with stroke rate. Together, these results suggest that although antiphase rowing is less stable (i.e., less resistant to perturbation), potential on-water benefits of antiphase over in-phase rowing may actually increase with stroke rate. PMID:26185987

  6. Measurement system for 3-D foot coordinates and parameters

    NASA Astrophysics Data System (ADS)

    Liu, Guozhong; Li, Yunhui; Wang, Boxiong; Shi, Hui; Luo, Xiuzhi

    2008-12-01

    The 3-D foot-shape measurement system based on laser-line-scanning principle and the model of the measurement system were presented. Errors caused by nonlinearity of CCD cameras and caused by installation can be eliminated by using the global calibration method for CCD cameras, which based on nonlinear coordinate mapping function and the optimized method. A local foot coordinate system is defined with the Pternion and the Acropodion extracted from the boundaries of foot projections. The characteristic points can thus be located and foot parameters be extracted automatically by the local foot coordinate system and the related sections. Foot measurements for about 200 participants were conducted and the measurement results for male and female participants were presented. 3-D foot coordinates and parameters measurement makes it possible to realize custom-made shoe-making and shows great prosperity in shoe design, foot orthopaedic treatment, shoe size standardization, and establishment of a feet database for consumers.

  7. Coordinate Measuring Machine Pit Artifact Inspection Procedure

    SciTech Connect

    Montano, Joshua D.

    2012-07-31

    The goal of this document is to outline a procedure for dimensional measurement of Los Alamos National Laboratory's CMM Pit Artifact. This procedure will be used by the Manufacturing Practice's Inspection Technology Subgroup of the Interagency Manufacturing Operations Group and Joint Operations Weapon Operations Group (IMOG/JOWOG 39) round robin participants. The intent is to assess the state of industry within the Nuclear Weapons Complex for measurements made on this type of part and find which current measurement strategies and techniques produce the best results.

  8. Advanced techniques for constrained internal coordinate molecular dynamics.

    PubMed

    Wagner, Jeffrey R; Balaraman, Gouthaman S; Niesen, Michiel J M; Larsen, Adrien B; Jain, Abhinandan; Vaidehi, Nagarajan

    2013-04-30

    Internal coordinate molecular dynamics (ICMD) methods provide a more natural description of a protein by using bond, angle, and torsional coordinates instead of a Cartesian coordinate representation. Freezing high-frequency bonds and angles in the ICMD model gives rise to constrained ICMD (CICMD) models. There are several theoretical aspects that need to be developed to make the CICMD method robust and widely usable. In this article, we have designed a new framework for (1) initializing velocities for nonindependent CICMD coordinates, (2) efficient computation of center of mass velocity during CICMD simulations, (3) using advanced integrators such as Runge-Kutta, Lobatto, and adaptive CVODE for CICMD simulations, and (4) cancelling out the "flying ice cube effect" that sometimes arises in Nosé-Hoover dynamics. The Generalized Newton-Euler Inverse Mass Operator (GNEIMO) method is an implementation of a CICMD method that we have developed to study protein dynamics. GNEIMO allows for a hierarchy of coarse-grained simulation models based on the ability to rigidly constrain any group of atoms. In this article, we perform tests on the Lobatto and Runge-Kutta integrators to determine optimal simulation parameters. We also implement an adaptive coarse-graining tool using the GNEIMO Python interface. This tool enables the secondary structure-guided "freezing and thawing" of degrees of freedom in the molecule on the fly during molecular dynamics simulations and is shown to fold four proteins to their native topologies. With these advancements, we envision the use of the GNEIMO method in protein structure prediction, structure refinement, and in studying domain motion.

  9. Coordination of Cellular Dynamics Contributes to Tooth Epithelium Deformations

    PubMed Central

    Morita, Ritsuko; Kihira, Miho; Nakatsu, Yousuke; Nomoto, Yohei; Ogawa, Miho; Ohashi, Kazumasa; Mizuno, Kensaku; Tachikawa, Tetsuhiko; Ishimoto, Yukitaka; Morishita, Yoshihiro; Tsuji, Takashi

    2016-01-01

    The morphologies of ectodermal organs are shaped by appropriate combinations of several deformation modes, such as invagination and anisotropic tissue elongation. However, how multicellular dynamics are coordinated during deformation processes remains to be elucidated. Here, we developed a four-dimensional (4D) analysis system for tracking cell movement and division at a single-cell resolution in developing tooth epithelium. The expression patterns of a Fucci probe clarified the region- and stage-specific cell cycle patterns within the tooth germ, which were in good agreement with the pattern of the volume growth rate estimated from tissue-level deformation analysis. Cellular motility was higher in the regions with higher growth rates, while the mitotic orientation was significantly biased along the direction of tissue elongation in the epithelium. Further, these spatio-temporal patterns of cellular dynamics and tissue-level deformation were highly correlated with that of the activity of cofilin, which is an actin depolymerization factor, suggesting that the coordination of cellular dynamics via actin remodeling plays an important role in tooth epithelial morphogenesis. Our system enhances the understanding of how cellular behaviors are coordinated during ectodermal organogenesis, which cannot be observed from histological analyses. PMID:27588418

  10. Coordination of Cellular Dynamics Contributes to Tooth Epithelium Deformations.

    PubMed

    Morita, Ritsuko; Kihira, Miho; Nakatsu, Yousuke; Nomoto, Yohei; Ogawa, Miho; Ohashi, Kazumasa; Mizuno, Kensaku; Tachikawa, Tetsuhiko; Ishimoto, Yukitaka; Morishita, Yoshihiro; Tsuji, Takashi

    2016-01-01

    The morphologies of ectodermal organs are shaped by appropriate combinations of several deformation modes, such as invagination and anisotropic tissue elongation. However, how multicellular dynamics are coordinated during deformation processes remains to be elucidated. Here, we developed a four-dimensional (4D) analysis system for tracking cell movement and division at a single-cell resolution in developing tooth epithelium. The expression patterns of a Fucci probe clarified the region- and stage-specific cell cycle patterns within the tooth germ, which were in good agreement with the pattern of the volume growth rate estimated from tissue-level deformation analysis. Cellular motility was higher in the regions with higher growth rates, while the mitotic orientation was significantly biased along the direction of tissue elongation in the epithelium. Further, these spatio-temporal patterns of cellular dynamics and tissue-level deformation were highly correlated with that of the activity of cofilin, which is an actin depolymerization factor, suggesting that the coordination of cellular dynamics via actin remodeling plays an important role in tooth epithelial morphogenesis. Our system enhances the understanding of how cellular behaviors are coordinated during ectodermal organogenesis, which cannot be observed from histological analyses. PMID:27588418

  11. The teaching of polar coordinates with dynamic mathematics software

    NASA Astrophysics Data System (ADS)

    Zengin, Yılmaz; Tatar, Enver

    2015-01-01

    The purpose of this study was to determine the effects of dynamic mathematics software on the achievement of pre-service mathematics teachers in the topic of polar coordinates and to solicit their opinions about computer-assisted instruction. The study was conducted for 11 weeks with 33 pre-service teachers in the Department of Mathematics Education Program of a state university in Turkey. Data collection tools comprised a knowledge test of polar coordinates and administration of a semi-structured interview form developed by the researchers who conducted the study using an embedded design as part of a mixed-method research. The results of data analysis showed that the computer-assisted instruction method in which dynamic mathematics software was used positively contributed to the success of pre-service teachers in understanding the subject of polar coordinates. Furthermore, it was found that pre-service teachers supported the use of this method in lessons as it provides visualization, increases retention, concretization of abstract mathematical structures, better understanding and learning, and creates an interesting and interactive learning environment.

  12. A composite scheme for gas dynamics in Lagrangian coordinates

    SciTech Connect

    Shashkov, M.; Wendroff, B.

    1999-04-10

    One cycle of a composite finite difference scheme is defined as several time steps of an oscillatory scheme such as Lax-Wendroff followed by one step of a diffusive scheme such as Lax-Friedrichs. The authors apply this idea to gas dynamics in Lagrangian coordinates. They show numerical results in two dimensions for Noh`s infinite strength shock problem and the Sedov blast wave problem, and for several one-dimensional problems including a Riemann problem with a contact discontinuity. For Noh`s problem the composite scheme produces a better result than that obtained with a more conventional Lagrangian code.

  13. Measuring a hidden coordinate: Rate-exchange kinetics from 3D correlation functions

    NASA Astrophysics Data System (ADS)

    Berg, Mark A.; Darvin, Jason R.

    2016-08-01

    Nonexponential kinetics imply the existence of at least one slow variable other than the observable, that is, the system has a "hidden" coordinate. We develop a simple, but general, model that allows multidimensional correlation functions to be calculated for these systems. Homogeneous and heterogeneous mechanisms are both included, and slow exchange of the rates is allowed. This model shows that 2D and 3D correlation functions of the observable measure the distribution and kinetics of the hidden coordinate controlling the rate exchange. Both the mean exchange time and the shape of the exchange relaxation are measurable. However, complications arise because higher correlation functions are sums of multiple "pathways," each of which measures different dynamics. Only one 3D pathway involves exchange dynamics. Care must be used to extract exchange dynamics without contamination from other processes.

  14. Combined non-contact coordinate measurement system and calibration method

    NASA Astrophysics Data System (ADS)

    Fan, Yiyan; Zhao, Bin

    2015-07-01

    A combined non-contact measurement system comprising attitude angle sensor, angle encoder, laser rangefinder, and total station is adopted to measure the spatial coordinate of the hidden zones in large-scale space. The laser from the total station is aimed at the optical system of the attitude angle sensor to obtain the spatial coordinate and the spatial attitude angles. Then, the angle encoder driven by a stepping motor is rotated to drive the laser rangefinder to direct at the measured point. This approach is used to obtain the distance from the rangefinder to the measured point and the angle of the angle encoder. Finally, the spatial coordinates of the measured point can be calculated by using these measured parameters. For the measurement system, we propose a weighted least squares (WLS) calibration method, in which weights are determined for the angular distribution density. Experimental results show that the measurement system could expand the scale and achieve reliable precision during combined measurement and the measurement error of the weighted least squares method is less than that of the ordinary least square (OLS) method.

  15. Dynamics of coordination in cross-country skiing.

    PubMed

    Cignetti, F; Schena, F; Zanone, P G; Rouard, A

    2009-04-01

    The aim of the present study was to identify modes of coordination in cross-country skiing from a dynamical systems perspective. Participants (N=8) skied on a treadmill using classical techniques with varying steepness (i.e., 0 degrees-7 degrees). Coordination was evaluated in terms of the relative frequency and relative phase between upper arms and thighs. Results revealed that the limb movements were systematically attracted towards low integer frequency ratios (i.e., 1:1 and 2:1) and in-phase (phi approximately 0 degrees ) and anti-phase relationships (phi approximately 180 degrees). The increase in steepness produced shifts between the attractive modes of limb movements and a loss of stability was observed during transitions. These results suggest that principles of coordination between limbs in cross-country skiing are akin to those of non-linear coupled oscillators, as documented for a broad range of motor activities. Yet, differences with such classical findings are discussed reflecting the specific biomechanical constraints of cross-country skiing.

  16. Unified Selenocentric Reference Coordinates Net in the Dynamic System

    NASA Astrophysics Data System (ADS)

    Nefedyev, Yuri; Petrova, Natalia; Varaksina, Natalia

    In this report the task of the making selenocentric inertial reference net is solved. The purpose is making summary reference net by expansion KSC-1162 selenodetic system using 12 cosmic and ground selenodesic catalogues. The prospective analysis of this net was performed. These selenocentric reference catalogue covers full visible and a part of far lunar sides. Modern cosmic technologies need the accurate coordinate - temporal support including reference frame realization, inertial and dynamic system orientation and studying dynamic and geometry celestial bodies. That refers to dynamic and geometric selenocentric lunar parameters. The catalogue based on mission “Apollo” and reference nets of the west lunar hemisphere made by missions “Zond 5”, ”Zond 8” cover small part of the Moon surface. Three ALSEP stations were used to transform “Apollo” topographic coordinates. Transformation mean-square errors are less than 80 meters and measurement’s errors are about 60 meters. On this account positions inaccuracy near and between ALSEP stations are less 150 meters. The offset from place of the location ALSEP enlarges the supposed mistake is more than 300 m and this is a major part of the lunar surface. In solving the problem of high-precision condensation and expansion of fundamental selenocentric net KSC-1162 on the visible side of the Moon and lunar far side were obtained following new results: a) the analysis and investigation of the accuracy of basic net contained in ULCN were carried out; b) the decryption of common objects for coordinate systems which are being explored was executed; c) the extension of the mathematical content package TSC was carried out; d) the development of TSC as an expert system of universal transformation planet's coordinates was carried out; e) the possibility of applying the ARM-approach to the problem TC on common objects, which allows to find optimal parameter estimation and model structure of TC was confirmed; f) the

  17. Optical 3D-coordinate measuring system using structured light

    NASA Astrophysics Data System (ADS)

    Schreiber, Wolfgang; Notni, Gunther; Kuehmstedt, Peter; Gerber, Joerg; Kowarschik, Richard M.

    1996-09-01

    The paper is aimed at the description of an optical shape measuring technique based on a consistent principle using fringe projection technique. We demonstrate a real 3D- coordinate measuring system where the sale of coordinates is given only by the illumination-structures. This method has the advantages that the aberration of the observing system and the depth-dependent imaging scale have no influence on the measuring accuracy and, moreover, the measurements are independent of the position of the camera with respect to the object under test. Furthermore, it is shown that the influence of specular effects of the surface on the measuring result can be eliminated. Moreover, we developed a very simple algorithm to calibrate the measuring system. The measuring examples show that a measuring accuracy of 10-4 (i.e. 10 micrometers ) within an object volume of 100 X 100 X 70 mm3 is achievable. Furthermore, it is demonstrated that the set of coordinate values can be processed in CNC- and CAD-systems.

  18. Quadratic elongation: A quantitative measure of distortion in coordination polyhedra

    USGS Publications Warehouse

    Robinson, Kelly F.; Gibbs, G.V.; Ribbe, P.H.

    1971-01-01

    Quadratic elongation and the variance of bond angles are linearly correlated for distorted octahedral and tetrahedral coordination complexes, both of which show variations in bond length and bond angle. The quadratic elonga tion is dimensionless, giving a quantitative measure of polyhedral distortion which is independent of the effective size of the polyhedron.

  19. Measurement error analysis of three dimensional coordinates of tomatoes acquired using the binocular stereo vision

    NASA Astrophysics Data System (ADS)

    Xiang, Rong

    2014-09-01

    This study analyzes the measurement errors of three dimensional coordinates of binocular stereo vision for tomatoes based on three stereo matching methods, centroid-based matching, area-based matching, and combination matching to improve the localization accuracy of the binocular stereo vision system of tomato harvesting robots. Centroid-based matching was realized through the matching of the feature points of centroids of tomato regions. Area-based matching was realized based on the gray similarity between two neighborhoods of two pixels to be matched in stereo images. Combination matching was realized using the rough disparity acquired through centroid-based matching as the center of the dynamic disparity range which was used in area-based matching. After stereo matching, three dimensional coordinates of tomatoes were acquired using the triangle range finding principle. Test results based on 225 stereo images captured at the distances from 300 to 1000 mm of 3 tomatoes showed that the measurement errors of x coordinates were small, and can meet the need of harvesting robots. However, the measurement biases of y coordinates and depth values were large, and the measurement variation of depth values was also large. Therefore, the measurement biases of y coordinates and depth values, and the measurement variation of depth values should be corrected in the future researches.

  20. Strategy for non-contact freeform measurements with a cylinder coordinate measuring instrument

    NASA Astrophysics Data System (ADS)

    Beutler, A.

    2015-10-01

    The strategy for measuring and analyzing freeforms with a new high precision cylinder coordinate measuring instrument equipped with an optical point sensor is presented. As freeforms compared to aspheres are not rotationally symmetric considering outline and shape the measuring process has to be designed in new ways. In addition fiducials on the sample or fixture have to be measured to determine position and orientation, i.e. a coordinate system, of the sample. In the following analysis process this coordinate system has to be taken into account. The performance of the measuring instrument is demonstrated and measuring results of different samples are shown.

  1. Mitochondria: the cellular hub of the dynamic coordinated network.

    PubMed

    Yin, Fei; Cadenas, Enrique

    2015-04-20

    Mitochondria are the powerhouses of the eukaryotic cell. After billions of years of evolution, mitochondria have adaptively integrated into the symbiont. Such integration is not only evidenced by the consolidation of genetic information, that is, the transfer of most mitochondrial genes into the nucleus, but also manifested by the functional recombination by which mitochondria participate seamlessly in various cellular processes. In the past decade, the field of mitochondria biology has been focused on the dynamic and interactive features of these semiautonomous organelles. Aspects of a complex multilayer quality control system coordinating mitochondrial function and environmental changes are being uncovered and refined. This Forum summarizes the recent progress of these critical topics, with a focus on the dynamic quality control of mitochondrial reticulum, including their biogenesis, dynamic remodeling, and degradation, as well as the homeostasis of the mitochondrial proteome. These diverse but interconnected mechanisms are found to be critical in the maintenance of a functional, efficient, and responsive mitochondrial population and could therefore become therapeutic targets in numerous mitochondrion-implicated disorders.

  2. Articulated Arm Coordinate Measuring Machine Calibration by Laser Tracker Multilateration

    PubMed Central

    Majarena, Ana C.; Brau, Agustín; Velázquez, Jesús

    2014-01-01

    A new procedure for the calibration of an articulated arm coordinate measuring machine (AACMM) is presented in this paper. First, a self-calibration algorithm of four laser trackers (LTs) is developed. The spatial localization of a retroreflector target, placed in different positions within the workspace, is determined by means of a geometric multilateration system constructed from the four LTs. Next, a nonlinear optimization algorithm for the identification procedure of the AACMM is explained. An objective function based on Euclidean distances and standard deviations is developed. This function is obtained from the captured nominal data (given by the LTs used as a gauge instrument) and the data obtained by the AACMM and compares the measured and calculated coordinates of the target to obtain the identified model parameters that minimize this difference. Finally, results show that the procedure presented, using the measurements of the LTs as a gauge instrument, is very effective by improving the AACMM precision. PMID:24688418

  3. NMR with generalized dynamics of spin and spatial coordinates

    SciTech Connect

    Lee, Chang Jae

    1987-11-01

    This work is concerned with theoretical and experimental aspects of the generalized dynamics of nuclear spin and spatial coordinates under magnetic-field pulses and mechanical motions. The main text begins with an introduction to the concept of ''fictitious'' interactions. A systematic method for constructing fictitious spin-1/2 operators is given. The interaction of spins with a quantized-field is described. The concept of the fictitious interactions under the irradiation of multiple pulses is utilized to design sequences for selectively averaging linear and bilinear operators. Relations between the low-field sequences and high-field iterative schemes are clarified. These relations and the transformation properties of the spin operators are exploited to develop schemes for heteronuclear decoupling of multi-level systems. The resulting schemes are evaluated for heteronuclear decoupling of a dilute spin-1/2 from a spin-1 in liquid crystal samples and from a homonuclear spin-1/2 pair in liquids. A relation between the spin and the spatial variables is discussed. The transformation properties of the spin operators are applied to spatial coordinates and utilized to develop methods for removing the orientational dependence responsible for line broadening in a powder sample. Elimination of the second order quadrupole effects, as well as the first order anisotropies is discussed. It is shown that various sources of line broadening can effectively be eliminated by spinning and/or hopping the sample about judiciously chosen axes along with appropriate radio-frequency pulse sequences.

  4. Achieving Coordination through Dynamic Construction of Open Workflows

    NASA Astrophysics Data System (ADS)

    Thomas, Louis; Wilson, Justin; Roman, Gruia-Catalin; Gill, Christopher

    Workflow middleware executes tasks orchestrated by rules defined in a carefully handcrafted static graph. Workflow management systems have proved effective for service-oriented business automation in stable, wired infrastructures. We introduce a radically new paradigm for workflow construction and execution called open workflow to support goal-directed coordination among physically mobile people and devices that form a transient community over an ad hoc wireless network. The quintessential feature of the open workflow paradigm is dynamic construction of custom, context-specific workflows in response to unpredictable and evolving circumstances by exploiting the knowledge and services available within a given spatiotemporal context. This paper introduces the open workflow approach, surveys open research challenges in this promising new field, and presents algorithmic, architectural, and evaluation results for the first practical realization of an open workflow management system.

  5. Heuristic control of kinetic energy in dynamic reaction coordinate calculations.

    PubMed

    Hellweg, Arnim

    2013-08-01

    For the understanding and prediction of chemical reactions, detailed knowledge of the minimum energy path between reactants and transition state is of utmost importance. Stewart et al. (J. Comput. Chem. 1987, 8, 1117) proposed the usage of molecular trajectories calculated from Newton's equations of motion for an efficient reaction path following. Two operational modes are possible thereby: intrinsic (IRC) and dynamic reaction coordinate calculations (DRC). The technical difference between these modes is that in an IRC calculation the kinetic energy of the nuclei is quenched while the total energy is conserved in DRC calculations. In this work, a heuristic control methodology of atomic kinetic energies in DRC calculations using fuzzy logic is proposed. A diversified test set of 10 reactions has been collected to examine the performance of this approach. Fuzzy rule-based models are found to be a convenient way to make the determination of accessible paths of chemical reactions computationally efficient.

  6. Coordinated scheduling for dynamic real-time systems

    NASA Technical Reports Server (NTRS)

    Natarajan, Swaminathan; Zhao, Wei

    1994-01-01

    In this project, we addressed issues in coordinated scheduling for dynamic real-time systems. In particular, we concentrated on design and implementation of a new distributed real-time system called R-Shell. The design objective of R-Shell is to provide computing support for space programs that have large, complex, fault-tolerant distributed real-time applications. In R-shell, the approach is based on the concept of scheduling agents, which reside in the application run-time environment, and are customized to provide just those resource management functions which are needed by the specific application. With this approach, we avoid the need for a sophisticated OS which provides a variety of generalized functionality, while still not burdening application programmers with heavy responsibility for resource management. In this report, we discuss the R-Shell approach, summarize the achievement of the project, and describe a preliminary prototype of R-Shell system.

  7. New three-dimensional fiber probe for multisensor coordinate measurement

    NASA Astrophysics Data System (ADS)

    Ettemeyer, Andreas

    2012-08-01

    Increasing manufacturing accuracy requirements enforce the development of innovative and highly sensitive measuring tools. Especially for measurement with submicrometer accuracy, the sensor principle has to be chosen appropriately for each measurement surface. Modern multisensor coordinate measurement systems allow automatic selection of different sensor heads to measure different areas or properties of a sample. As an example, different types of optical sensors as well as tactile sensors can be used within the same measuring system. I describe different principles of optical sensors used in multisensor coordinate measurement systems as well as a new approach for tactile measurement with submicrometer accuracy. A special fiber probe has been developed. The tip of the fiber probe is formed as a sphere. The lateral position of this sphere is observed by a microscope objective and can be determined within a fraction of a micrometer. Additionally, a novel optical setup now allows the determination of the z-position of the fiber tip with submicrometer accuracy. For this purpose, an interferometer setup is used. The laser light is coupled into the optical fiber. The light exiting the fiber tip is collected by the microscope objective and superposed with a reference wave, generated directly from the laser. The result is an interference signal that is recorded by the camera and processed by a computer. With this setup, the z-displacement of the fiber sphere can be measured with an accuracy of a fraction of the laser wavelength used.

  8. Coordinate measuring machine test standard apparatus and method

    DOEpatents

    Bieg, Lothar F.

    1994-08-30

    A coordinate measuring machine test standard apparatus and method which iudes a rotary spindle having an upper phase plate and an axis of rotation, a kinematic ball mount attached to the phase plate concentric with the axis of rotation of the phase plate, a groove mounted at the circumference of the phase plate, and an arm assembly which rests in the groove. The arm assembly has a small sphere at one end and a large sphere at the other end. The small sphere may be a coordinate measuring machine probe tip and may have variable diameters. The large sphere is secured in the kinematic ball mount and the arm is held in the groove. The kinematic ball mount includes at least three mounting spheres and the groove is an angular locating groove including at least two locking spheres. The arm may have a hollow inner core and an outer layer. The rotary spindle may be a ratio reducer. The device is used to evaluate the measuring performance of a coordinate measuring machine for periodic recertification, including 2 and 3 dimensional accuracy, squareness, straightness, and angular accuracy.

  9. Coordinate measuring machine test standard apparatus and method

    DOEpatents

    Bieg, L.F.

    1994-08-30

    A coordinate measuring machine test standard apparatus and method are disclosed which includes a rotary spindle having an upper phase plate and an axis of rotation, a kinematic ball mount attached to the phase plate concentric with the axis of rotation of the phase plate, a groove mounted at the circumference of the phase plate, and an arm assembly which rests in the groove. The arm assembly has a small sphere at one end and a large sphere at the other end. The small sphere may be a coordinate measuring machine probe tip and may have variable diameters. The large sphere is secured in the kinematic ball mount and the arm is held in the groove. The kinematic ball mount includes at least three mounting spheres and the groove is an angular locating groove including at least two locking spheres. The arm may have a hollow inner core and an outer layer. The rotary spindle may be a ratio reducer. The device is used to evaluate the measuring performance of a coordinate measuring machine for periodic recertification, including 2 and 3 dimensional accuracy, squareness, straightness, and angular accuracy. 5 figs.

  10. Dynamic coordination of macronutrient balance during infant growth

    PubMed Central

    Jordan, Peter N; Hall, Kevin D

    2008-01-01

    Background Complex dynamic changes in body composition, dietary intake, energy expenditure, and macronutrient oxidation occur during infant growth. Although previous investigators have focused on energy requirements for normal growth, little is known about the dynamic coordination of macronutrient balance. Objective Our objective was to develop a mathematical model of the dynamic relations between diet, macronutrient oxidation, and energy expenditure during normal infant growth. Design We developed a mathematical model that integrates longitudinal data on changes of body composition and carbon dioxide production determined with the doubly labeled water method to calculate both energy intake requirements and macronutrient oxidation rates during normal infant growth. Results The calculated fat oxidation rate was initially <20 kcal · kg-1 · d-1, despite the consumption of >60 kcal · kg-1 · d-1 of dietary fat. This discrepancy was maintained until ≈ 6 mo, after which fat intake was only slightly greater than fat oxidation. Nonfat oxidation closely followed nonfat dietary intake for the duration of the period studied. Model calculations of the energy intake requirements for normal growth were slightly lower than previous estimates. The calculations were robust to variations of body weight, body composition, and diet composition input data, but depended sensitively on variations of carbon dioxide production data. Conclusions Our model presents a dynamic picture of how macronutrient oxidation adapts in concert with dietary changes and energy expenditure to give rise to normal tissue deposition. The model integrates a variety of data in a self-consistent way, simulating the complex metabolic adaptations occurring during normal growth while extracting important physiologic information from the data that would otherwise be unavailable. PMID:18326609

  11. 3D fiber probe for multi sensor coordinate measurement

    NASA Astrophysics Data System (ADS)

    Ettemeyer, A.

    2011-12-01

    Increasing manufacturing accuracy requirements enforce the development of innovative and highly sensitive measuring tools. Especially for measurement with sub micrometer accuracy, the sensor principle has to be chosen appropriately for each measurement surface. Modern multi sensor coordinate measurements systems allow automatic selection of different sensor heads to measure different areas or properties of a sample. As example, different types of optical sensors as well as tactile sensors can be used with the same machine. In this paper we describe different principles of optical sensors used in multi sensor coordinate measurement systems as well as a new approach for tactile measurement with sub micrometer accuracy. A special fiber probe has been developed. The tip of the fiber probe is formed as a sphere. The lateral position of this sphere is observed by a microscope optics and can be determined to a fraction of a micrometer. Additionally, a novel optical set-up now even allows the determination of the z-position of the fiber tip with sub micrometer accuracy. For this purpose we use an interferometric set-up. The light of laser is coupled into the optical fiber. The light, exiting the fiber tip is collected by a microscope optics and superposed with a reference wave, generated directly from the laser. The result is an interferometric signal which is recorded by the camera and processed by a computer. With this set-up, the zdisplacement of the fiber sphere can be measured with an accuracy of a fraction of the used laser wavelength.

  12. Advanced coordinate measuring machine at Sandia National Laboratories

    NASA Astrophysics Data System (ADS)

    Pilkey, R. D.; Klevgard, P. A.

    1993-03-01

    Sandia National Laboratories/California has acquired a new Moore M-48V CNC five-axis universal coordinate measuring machine (CMM). Site preparation, acceptance testing, and initial performance results are discussed. Unique features of the machine include a ceramic ram and vacuum evacuated laser pathways (VELPS). The implementation of a VELPS system on the machine imposed certain design requirements and entailed certain start-up problems. The machine's projected capabilities, workload, and research possibilities are outlined.

  13. Advanced coordinate measuring machine at Sandia National Laboratories/California

    SciTech Connect

    Pilkey, R.D.; Klevgard, P.A.

    1993-03-01

    Sandia National Laboratories/California has acquired a new Moore M-48V CNC five-axis universal coordinate measuring machine (CMM). Site preparation, acceptance testing, and initial performance results are discussed. Unique features of the machine include a ceramic ram and vacuum evacuated laser pathways (VELPS). The implementation of a VELPS system on the machine imposed certain design requirements and entailed certain start-up problems. The machine's projected capabilities, workload, and research possibilities are outlined.

  14. Advanced coordinate measuring machine at Sandia National Laboratories/California

    SciTech Connect

    Pilkey, R.D.; Klevgard, P.A.

    1993-03-01

    Sandia National Laboratories/California has acquired a new Moore M-48V CNC five-axis universal coordinate measuring machine (CMM). Site preparation, acceptance testing, and initial performance results are discussed. Unique features of the machine include a ceramic ram and vacuum evacuated laser pathways (VELPS). The implementation of a VELPS system on the machine imposed certain design requirements and entailed certain start-up problems. The machine`s projected capabilities, workload, and research possibilities are outlined.

  15. Vertical coordinates measurement based on intersection laser screens

    NASA Astrophysics Data System (ADS)

    Zhang, Bin; Wang, Zhaoba; Zhao, Donge; Liu, Ji

    2015-10-01

    In order to solve the weakness of traditional vertical target coordinate measurement, such as complex structure, inconvenient debugging and difficult to form a large area target, a method based on intersection laser screens was proposed. The effective area of was constituted by the intersection of two fan-shaped laser screens. Photodiode (PD) array was used to measure the intensity of laser light. When the projectile passes through the laser screens, the corresponding PDs receive signal. After signal processing and adaptive threshold comparator circuit processing, the signal is transmitted to PC to calculate the projectile target coordinate. The calculation method of feature point and the calculation process of coordinate were described in detail. Error distribution in effective area was analyzed. Experiment was carried out by using simulating projectile and the principle prototype whose effective target area is 1m×1m. The result shows that the precision of location measurement is up to 2mm. The method has the advantages of simple structure, convenient debugging. It is easy to construct a larger area target, and the maximum effective area can reach to 6m×6m.

  16. Project Vesta: A Laboratory Exercise on the Measurement of Celestial Coordinates

    ERIC Educational Resources Information Center

    Laird, David E.

    1974-01-01

    Described is an activity that was developed to measure celestial coordinates. Pictures were taken of the asteroid Vesta, coordinates for reference stars determined, and then celestial coordinates of Vesta were determined with assistance of a computer. (RH)

  17. Statistical process control (SPC) for coordinate measurement machines

    SciTech Connect

    Escher, R.N.

    2000-01-04

    The application of process capability analysis, using designed experiments, and gage capability studies as they apply to coordinate measurement machine (CMM) uncertainty analysis and control will be demonstrated. The use of control standards in designed experiments, and the use of range charts and moving range charts to separate measurement error into it's discrete components will be discussed. The method used to monitor and analyze the components of repeatability and reproducibility will be presented with specific emphasis on how to use control charts to determine and monitor CMM performance and capability, and stay within your uncertainty assumptions.

  18. Decision-making ability of Physarum polycephalum enhanced by its coordinated spatiotemporal oscillatory dynamics.

    PubMed

    Iwayama, Koji; Zhu, Liping; Hirata, Yoshito; Aono, Masashi; Hara, Masahiko; Aihara, Kazuyuki

    2016-06-01

    An amoeboid unicellular organism, a plasmodium of the true slime mold Physarum polycephalum, exhibits complex spatiotemporal oscillatory dynamics and sophisticated information processing capabilities while deforming its amorphous body. We previously devised an 'amoeba-based computer (ABC),' that implemented optical feedback control to lead this amoeboid organism to search for a solution to the traveling salesman problem (TSP). In the ABC, the shortest TSP route (the optimal solution) is represented by the shape of the organism in which the body area (nutrient absorption) is maximized while the risk of being exposed to aversive light stimuli is minimized. The shortness of the TSP route found by ABC, therefore, serves as a quantitative measure of the optimality of the decision made by the organism. However, it remains unclear how the decision-making ability of the organism originates from the oscillatory dynamics of the organism. We investigated the number of coexisting traveling waves in the spatiotemporal patterns of the oscillatory dynamics of the organism. We show that a shorter TSP route can be found when the organism exhibits a lower number of traveling waves. The results imply that the oscillatory dynamics are highly coordinated throughout the global body. Based on the results, we discuss the fact that the decision-making ability of the organism can be enhanced not by uncorrelated random fluctuations, but by its highly coordinated oscillatory dynamics. PMID:27070463

  19. Dimensional coordinate measurements: application in characterizing cervical spine motion

    NASA Astrophysics Data System (ADS)

    Zheng, Weilong; Li, Linan; Wang, Shibin; Wang, Zhiyong; Shi, Nianke; Xue, Yuan

    2014-06-01

    Cervical spine as a complicated part in the human body, the form of its movement is diverse. The movements of the segments of vertebrae are three-dimensional, and it is reflected in the changes of the angle between two joint and the displacement in different directions. Under normal conditions, cervical can flex, extend, lateral flex and rotate. For there is no relative motion between measuring marks fixed on one segment of cervical vertebra, the cervical vertebrae with three marked points can be seen as a body. Body's motion in space can be decomposed into translational movement and rotational movement around a base point .This study concerns the calculation of dimensional coordinate of the marked points pasted to the human body's cervical spine by an optical method. Afterward, these measures will allow the calculation of motion parameters for every spine segment. For this study, we choose a three-dimensional measurement method based on binocular stereo vision. The object with marked points is placed in front of the CCD camera. Through each shot, we will get there two parallax images taken from different cameras. According to the principle of binocular vision we can be realized three-dimensional measurements. Cameras are erected parallelly. This paper describes the layout of experimental system and a mathematical model to get the coordinates.

  20. Biomechanics and muscle coordination of human walking: part II: lessons from dynamical simulations and clinical implications.

    PubMed

    Zajac, Felix E; Neptune, Richard R; Kautz, Steven A

    2003-02-01

    Principles of muscle coordination in gait have been based largely on analyses of body motion, ground reaction force and EMG measurements. However, data from dynamical simulations provide a cause-effect framework for analyzing these measurements; for example, Part I (Gait Posture, in press) of this two-part review described how force generation in a muscle affects the acceleration and energy flow among the segments. This Part II reviews the mechanical and coordination concepts arising from analyses of simulations of walking. Simple models have elucidated the basic multisegmented ballistic and passive mechanics of walking. Dynamical models driven by net joint moments have provided clues about coordination in healthy and pathological gait. Simulations driven by muscle excitations have highlighted the partial stability afforded by muscles with their viscoelastic-like properties and the predictability of walking performance when minimization of metabolic energy per unit distance is assumed. When combined with neural control models for exciting motoneuronal pools, simulations have shown how the integrative properties of the neuro-musculo-skeletal systems maintain a stable gait. Other analyses of walking simulations have revealed how individual muscles contribute to trunk support and progression. Finally, we discuss how biomechanical models and simulations may enhance our understanding of the mechanics and muscle function of walking in individuals with gait impairments.

  1. Spatially coordinated dynamic gene transcription in living pituitary tissue

    PubMed Central

    Featherstone, Karen; Hey, Kirsty; Momiji, Hiroshi; McNamara, Anne V; Patist, Amanda L; Woodburn, Joanna; Spiller, David G; Christian, Helen C; McNeilly, Alan S; Mullins, John J; Finkenstädt, Bärbel F; Rand, David A; White, Michael RH; Davis, Julian RE

    2016-01-01

    Transcription at individual genes in single cells is often pulsatile and stochastic. A key question emerges regarding how this behaviour contributes to tissue phenotype, but it has been a challenge to quantitatively analyse this in living cells over time, as opposed to studying snap-shots of gene expression state. We have used imaging of reporter gene expression to track transcription in living pituitary tissue. We integrated live-cell imaging data with statistical modelling for quantitative real-time estimation of the timing of switching between transcriptional states across a whole tissue. Multiple levels of transcription rate were identified, indicating that gene expression is not a simple binary ‘on-off’ process. Immature tissue displayed shorter durations of high-expressing states than the adult. In adult pituitary tissue, direct cell contacts involving gap junctions allowed local spatial coordination of prolactin gene expression. Our findings identify how heterogeneous transcriptional dynamics of single cells may contribute to overall tissue behaviour. DOI: http://dx.doi.org/10.7554/eLife.08494.001 PMID:26828110

  2. Automatic generation of active coordinates for quantum dynamics calculations: Application to the dynamics of benzene photochemistry

    SciTech Connect

    Lasorne, Benjamin; Sicilia, Fabrizio; Bearpark, Michael J.; Robb, Michael A.; Worth, Graham A.; Blancafort, Lluis

    2008-03-28

    A new practical method to generate a subspace of active coordinates for quantum dynamics calculations is presented. These reduced coordinates are obtained as the normal modes of an analytical quadratic representation of the energy difference between excited and ground states within the complete active space self-consistent field method. At the Franck-Condon point, the largest negative eigenvalues of this Hessian correspond to the photoactive modes: those that reduce the energy difference and lead to the conical intersection; eigenvalues close to 0 correspond to bath modes, while modes with large positive eigenvalues are photoinactive vibrations, which increase the energy difference. The efficacy of quantum dynamics run in the subspace of the photoactive modes is illustrated with the photochemistry of benzene, where theoretical simulations are designed to assist optimal control experiments.

  3. COSPAR, IAU, LSI Colloquium on Lunar Dynamics and Observational Coordinate Systems: Revised abstracts

    NASA Technical Reports Server (NTRS)

    Moutsoulas, M. (Editor)

    1973-01-01

    The proceedings of a colloquium on lunar dynamics and observational coordinate systems are presented. Discussions were held on the establishment of a fundamental reference system and on the lunar ephemerides. Abstracts of the subjects discussed at the meeting are submitted. Some of the topics discussed are: (1) coordinates of the Apollo retroreflectors, (2) determination of lunar baselines, (3) numerical series for the variations of lunar coordinates, (4) fundamental craters for establishing a lunar coordinate system, and (5) composite lunar gravity fields.

  4. Motor Coordination Dynamics Underlying Graphic Motion in 7- to 11-Year-Old Children

    ERIC Educational Resources Information Center

    Danna, Jeremy; Enderli, Fabienne; Athenes, Sylvie; Zanone, Pier-Giorgio

    2012-01-01

    Using concepts and tools of a dynamical system approach in order to understand motor coordination underlying graphomotor skills, the aim of the current study was to establish whether the basic coordination dynamics found in adults is already established in children at elementary school, when handwriting is trained and eventually acquired. In the…

  5. Dynamic Assessment of Binocular Eye Movement Coordination: Norms and Functional Implications

    PubMed Central

    Viirre, Erik

    2014-01-01

    Alignment of the two eyes is controlled by a finely tuned, fast acting system with components within the brain. Assessment of binocular alignment has classically been done statically. Eye positions are assessed in primary position and at eccentric angles to interpret the functional status of the oculomotor nerves and muscles. However, assessment of dynamic eye alignment, the coordination of the eyes during eye movements, has been less commonly carried out and has not been formalized with population norms. Clinicians are aware of slow eye movement dynamic alignment changes, such as that clinically observed in Intranuclear Ophthalmoplegia. But assessment of eye alignment during rapid eye movements, such as saccade or pursuit has not been part of neuro-ophthalmologic assessment. With the advent of inexpensive, high resolution recording systems, both eyes can be simultaneously recorded and their coordination during movement compared. Thus, we now have an opportunity to provide a laboratory based objective measurement of a gamut of binocular coordination systems. Recent research in humans has demonstrated increased variability of binocular coordination during divided attention. Variability is an interesting statistic that can be sensitively assessed in the velocity domain without extensive gaze position recalibration procedures during recording over long intervals. Variability can thus be used as a robust, long-term eye movement parameter with minimal intrusiveness to the subject. It is proposed that population studies of binocular coordination during eye movements be carried out to determine neurologic norms so that conditions such as brain injury and others can be assessed with a functional tool with objective parameters. PMID:24804278

  6. Study of variant design of SML-based coordinate measuring machines automatic measurement plan

    NASA Astrophysics Data System (ADS)

    Wang, Rui; Wang, Boxiong; Wang, Junying; Chen, Huacheng; Luo, Xiuzhi

    2006-11-01

    It is the trend of Coordinate Measuring Machine (CMM) measurement technology that creates measurement plan automatically. Based on Pro/CMM module of Pro/E software, the idea for automatic generation of the main DMIS (Dimensional Measuring Interface Standard) file of measurement plan is described. To satisfy the special measurement requirements of different customers conveniently, a method of variant design of DMIS file based on SML (Tabular Layouts of Article Characteristics) and the main DMIS file is proposed.

  7. Extracting numeric measurements and temporal coordinates from Japanese radiological reports

    NASA Astrophysics Data System (ADS)

    Imai, Takeshi; Onogi, Yuzo

    2004-04-01

    Medical records are written mainly, in natural language. The focus of this study is narrative radiological reports written in natural Japanese. These reports cannot be used for advanced retrieval, data mining, and so on, unless they are stored, using a structured format such as DICOM-SR. The goal is to structure narrative reports progressively, using natural language processing (NLP). Structure has many different levels, for example, DICOM-SR has three established levels -- basic text, enhanced and comprehensive. At the enhanced level, it is necessary to use numerical measurements and spatial & temporal coordinates. In this study, the wording used in the reports was first standardized, dictionaries were organized, and morphological analysis performed. Next, numerical measurements and temporal coordinates were extracted, and the objects to which they referred, analyzed. 10,000 CT and MR reports were separated into 82,122 sentences, and 34,269 of the 36,444 numerical descriptions were tagged. Periods, slashes, hyphens, and parentheses are ambiguously used in the description of enumerated lists, dates, image numbers, and anatomical names, as well as at the end of sentences; to resolve this ambiguity, descriptions were processed, according to the order -- date, size, unit, enumerated list, and abbreviation -- then, the tagged reports were separated into sentences.

  8. Automated fixturing planning for inspection on coordinate-measuring machine

    NASA Astrophysics Data System (ADS)

    Cheng, Ye; Cai, Fuzhi

    1995-08-01

    In manufacturing process design, one of the key problems is fixturing planning. This paper deals with automated fixturing planning for inspection process on coordinate measuring machine (CMM) in an automatic manufacturing system environment. A planning strategy is presented with analysis about difficulties in fixturing planning. The newly developed configurable fixture system was designed which is suitable for not only measuring process but also automated fixturing planning. The planning system determines the part orientation at the first. Then it analyzes the support surface and its four sides to make a decision about the fixing style and the distribution of the fixing points. The detailed fixture structure parameters and the part position are also generated. In application, the system performed fixturing planning for complicated regular non-rotational parts.

  9. Some notions of decentralization and coordination in large-scale dynamic systems

    NASA Technical Reports Server (NTRS)

    Chong, C. Y.

    1975-01-01

    Some notions of decentralization and coordination in the control of large-scale dynamic systems are discussed. Decentralization and coordination have always been important concepts in the study of large systems. Roughly speaking decentralization is the process of dividing a large problem into subproblems so that it can be handled more easily. Coordination is the manipulation of the subproblem so that the original problem is solved. The various types of decentralization and coordination that have been used to control dynamic systems are discussed. The emphasis was to distinguish between on-line and off-line operations to understand the results available by indicating the aspects of the problem which are decentralized.

  10. Reference coordinate systems for Earth dynamics: A preview

    NASA Technical Reports Server (NTRS)

    Mueller, I. I.

    1982-01-01

    Geodynamics is the subject of intensive international research during last decade. A common requirement for all investigations is the necessity of a well defined coordinate system attached to the Earth in some prescribed way. In addition, a well defined inertial coordinate system is also needed in which the motions of the terrestrial system can be monitored. The problems encountered when establishing such coordinate systems and the transformations between them are presented. In addition, problems related to the modeling of the deformable Earth are discussed. Finally, action items are listed which are necessary to assure that the reference system issue is resolved early and that uniformity is assured by means of international agreements.

  11. Reaction coordinates, one-dimensional Smoluchowski equations, and a test for dynamical self-consistency.

    PubMed

    Peters, Baron; Bolhuis, Peter G; Mullen, Ryan G; Shea, Joan-Emma

    2013-02-01

    We propose a method for identifying accurate reaction coordinates among a set of trial coordinates. The method applies to special cases where motion along the reaction coordinate follows a one-dimensional Smoluchowski equation. In these cases the reaction coordinate can predict its own short-time dynamical evolution, i.e., the dynamics projected from multiple dimensions onto the reaction coordinate depend only on the reaction coordinate itself. To test whether this property holds, we project an ensemble of short trajectory swarms onto trial coordinates and compare projections of individual swarms to projections of the ensemble of swarms. The comparison, quantified by the Kullback-Leibler divergence, is numerically performed for each isosurface of each trial coordinate. The ensemble of short dynamical trajectories is generated only once by sampling along an initial order parameter. The initial order parameter should separate the reactants and products with a free energy barrier, and distributions on isosurfaces of the initial parameter should be unimodal. The method is illustrated for three model free energy landscapes with anisotropic diffusion. Where exact coordinates can be obtained from Kramers-Langer-Berezhkovskii-Szabo theory, results from the new method agree with the exact results. We also examine characteristics of systems where the proposed method fails. We show how dynamical self-consistency is related (through the Chapman-Kolmogorov equation) to the earlier isocommittor criterion, which is based on longer paths.

  12. Mutual and asynchronous anticipation and action in sports as globally competitive and locally coordinative dynamics

    PubMed Central

    Fujii, Keisuke; Isaka, Tadao; Kouzaki, Motoki; Yamamoto, Yuji

    2015-01-01

    Humans interact by changing their actions, perceiving other’s actions and executing solutions in conflicting situations. Using oscillator models, nonlinear dynamics have been considered for describing these complex human movements as an emergence of self-organisation. However, these frameworks cannot explain the hierarchical structures of complex behaviours between conflicting inter-agent and adapting intra-agent systems, especially in sport competitions wherein mutually quick decision making and execution are required. Here we adopt a hybrid multiscale approach to model an attack-and-defend game during which both players predict the opponent’s movement and move with a delay. From both simulated and measured data, one synchronous outcome between two-agent (i.e. successful defence) can be described as one attractor. In contrast, the other coordination-breaking outcome (i.e. successful attack) cannot be explained using gradient dynamics because the asymmetric interaction cannot always assume a conserved physical quantity. Instead, we provide the asymmetric and asynchronous hierarchical dynamical models to discuss two-agent competition. Our framework suggests that possessing information about an opponent and oneself in local-coordinative and global-competitive scale enables us to gain a deeper understanding of sports competitions. We anticipate developments in the scientific fields of complex movement adapting to such uncontrolled environments. PMID:26538452

  13. Mutual and asynchronous anticipation and action in sports as globally competitive and locally coordinative dynamics.

    PubMed

    Fujii, Keisuke; Isaka, Tadao; Kouzaki, Motoki; Yamamoto, Yuji

    2015-01-01

    Humans interact by changing their actions, perceiving other's actions and executing solutions in conflicting situations. Using oscillator models, nonlinear dynamics have been considered for describing these complex human movements as an emergence of self-organisation. However, these frameworks cannot explain the hierarchical structures of complex behaviours between conflicting inter-agent and adapting intra-agent systems, especially in sport competitions wherein mutually quick decision making and execution are required. Here we adopt a hybrid multiscale approach to model an attack-and-defend game during which both players predict the opponent's movement and move with a delay. From both simulated and measured data, one synchronous outcome between two-agent (i.e. successful defence) can be described as one attractor. In contrast, the other coordination-breaking outcome (i.e. successful attack) cannot be explained using gradient dynamics because the asymmetric interaction cannot always assume a conserved physical quantity. Instead, we provide the asymmetric and asynchronous hierarchical dynamical models to discuss two-agent competition. Our framework suggests that possessing information about an opponent and oneself in local-coordinative and global-competitive scale enables us to gain a deeper understanding of sports competitions. We anticipate developments in the scientific fields of complex movement adapting to such uncontrolled environments.

  14. Mutual and asynchronous anticipation and action in sports as globally competitive and locally coordinative dynamics

    NASA Astrophysics Data System (ADS)

    Fujii, Keisuke; Isaka, Tadao; Kouzaki, Motoki; Yamamoto, Yuji

    2015-11-01

    Humans interact by changing their actions, perceiving other’s actions and executing solutions in conflicting situations. Using oscillator models, nonlinear dynamics have been considered for describing these complex human movements as an emergence of self-organisation. However, these frameworks cannot explain the hierarchical structures of complex behaviours between conflicting inter-agent and adapting intra-agent systems, especially in sport competitions wherein mutually quick decision making and execution are required. Here we adopt a hybrid multiscale approach to model an attack-and-defend game during which both players predict the opponent’s movement and move with a delay. From both simulated and measured data, one synchronous outcome between two-agent (i.e. successful defence) can be described as one attractor. In contrast, the other coordination-breaking outcome (i.e. successful attack) cannot be explained using gradient dynamics because the asymmetric interaction cannot always assume a conserved physical quantity. Instead, we provide the asymmetric and asynchronous hierarchical dynamical models to discuss two-agent competition. Our framework suggests that possessing information about an opponent and oneself in local-coordinative and global-competitive scale enables us to gain a deeper understanding of sports competitions. We anticipate developments in the scientific fields of complex movement adapting to such uncontrolled environments.

  15. Coordinated Energetic Particle Measurements Using Chandra, Cluster, and Polar

    NASA Astrophysics Data System (ADS)

    Mueller-Mellin, R.; Blake, J. B.; Baker, D.

    2003-12-01

    It is not well known in the magnetospheric physics community that the Chandra spacecraft carries a multi-element energetic particle telescope called EPHIN (Electron Proton Helium Instrument) fielded by the University of Kiel. For present purposes we are interested in electrons that are measured from greater than 30 keV to greater than 10 MeV. Chandra is in a highly elliptical orbit with a perigee of 16000 km, and apogee of 133,000 km and an inclination of 28 degrees. Fortuitously the line of apsides is relatively close to that of the Cluster constellation. A first use of the Chandra data has been a further examination of a substorm onset that occurred = 0408 UT on 27 August 2001, discussed in a publication by Baker et al. (2002). At that time the s/c coordinates in GSM were Chandra (-6.64, 16.15, 12.82); Cluster 3 (-19.15, -1.40, 1.54); Polar (-7.71, -4.50, 3.32). It can be seen that whereas Cluster and Polar were a bit post midnight and roughly radially aligned, Chandra was well pre-midnight at around 20 hrs. Yet the onset time of energetic electrons at Chandra was very close to that observed at Cluster and Polar. Furthermore, some pre-substorm bursts were also seen to be closely time coincident at Chandra and the other spacecraft. These observations give additional evidence about the scale size of the phenomena and will be discussed in detail along with other coordinated measurements. Baker et al. GRL 29, no. 24, 2190, 2002

  16. Segmented space: measuring tactile localisation in body coordinates.

    PubMed

    Harrar, Vanessa; Pritchett, Lisa M; Harris, Laurence R

    2013-01-01

    Previous research showing systematic localisation errors in touch perception related to eye and head position has suggested that touch is at least partially localised in a visual reference frame. However, many previous studies had participants report the location of tactile stimuli relative to a visual probe, which may force coding into a visual reference. Also, the visual probe could itself be subject to an effect of eye or head position. Thus, it is necessary to assess the perceived position of a tactile stimulus using a within-modality measure in order to make definitive conclusions about the coordinate system in which touch might be coded. Here, we present a novel method for measuring the perceived location of a touch in body coordinates: the Segmented Space Method (SSM). In the SSM participants imagine the region within which the stimulus could be presented divided into several equally spaced, and numbered, segments. Participants then simply report the number corresponding to the segment in which they perceived the stimulus. The SSM represents a simple and novel method that can be easily extended to other modalities by dividing any response space into numbered segments centred on some appropriate reference point (e.g. the head, the torso, the hand, or some point in space off the body). Here we apply SSM to the forearm during eccentric viewing and report localisation errors for touch similar to those previously reported using a crossmodal comparison. The data collected with the SSM strengthen the theory that tactile spatial localisation is generally coded in a visual reference frame even when visual coding is not required by the task.

  17. Tortoise Coordinate Transformation on Apparent Horizon of a Dynamical Black Hole

    NASA Astrophysics Data System (ADS)

    Liu, Xianming; Zhao, Zheng; Liu, Wenbiao

    Thinking of Hawking radiation calculation from a Schwarzschild black hole using Damour-Ruffini method, some key requirements of the tortoise coordinate transformation are pointed out. Extending these requirements to a dynamical black hole, a dynamical tortoise coordinate transformation is proposed. Under this new dynamical tortoise coordinate transformation, Hawking radiation from a Vaidya black hole can be got successfully using Damour-Ruffini method. Moreover, we also find that the radiation should be regarded as originating from the apparent horizon rather than the event horizon at least from the viewpoint of the first law of thermodynamics.

  18. Lifting particle coordinate changes of magnetic moment type to Vlasov-Maxwell Hamiltonian dynamics

    SciTech Connect

    Morrison, P. J.; Vittot, M.; Guillebon, L. de

    2013-03-15

    Techniques for coordinate changes that depend on both dependent and independent variables are developed and applied to the Maxwell-Vlasov Hamiltonian theory. Particle coordinate changes with a new velocity variable dependent on the magnetic field, with spatial coordinates unchanged, are lifted to the field theoretic level, by transforming the noncanonical Poisson bracket and Hamiltonian structure of the Vlasov-Maxwell dynamics. Several examples are given including magnetic coordinates, where the velocity is decomposed into components parallel and perpendicular to the local magnetic field, and the case of spherical velocity coordinates. An example of the lifting procedure is performed to obtain a simplified version of gyrokinetics, where the magnetic moment is used as a coordinate and the dynamics is reduced by elimination of the electric field energy in the Hamiltonian.

  19. Optimal Sampling of a Reaction Coordinate in Molecular Dynamics

    NASA Technical Reports Server (NTRS)

    Pohorille, Andrew

    2005-01-01

    Estimating how free energy changes with the state of a system is a central goal in applications of statistical mechanics to problems of chemical or biological interest. From these free energy changes it is possible, for example, to establish which states of the system are stable, what are their probabilities and how the equilibria between these states are influenced by external conditions. Free energies are also of great utility in determining kinetics of transitions between different states. A variety of methods have been developed to compute free energies of condensed phase systems. Here, I will focus on one class of methods - those that allow for calculating free energy changes along one or several generalized coordinates in the system, often called reaction coordinates or order parameters . Considering that in almost all cases of practical interest a significant computational effort is required to determine free energy changes along such coordinates it is hardly surprising that efficiencies of different methods are of great concern. In most cases, the main difficulty is associated with its shape along the reaction coordinate. If the free energy changes markedly along this coordinate Boltzmann sampling of its different values becomes highly non-uniform. This, in turn, may have considerable, detrimental effect on the performance of many methods for calculating free energies.

  20. Measuring mitotic spindle dynamics in budding yeast

    NASA Astrophysics Data System (ADS)

    Plumb, Kemp

    In order to carry out its life cycle and produce viable progeny through cell division, a cell must successfully coordinate and execute a number of complex processes with high fidelity, in an environment dominated by thermal noise. One important example of such a process is the assembly and positioning of the mitotic spindle prior to chromosome segregation. The mitotic spindle is a modular structure composed of two spindle pole bodies, separated in space and spanned by filamentous proteins called microtubules, along which the genetic material of the cell is held. The spindle is responsible for alignment and subsequent segregation of chromosomes into two equal parts; proper spindle positioning and timing ensure that genetic material is appropriately divided amongst mother and daughter cells. In this thesis, I describe fluorescence confocal microscopy and automated image analysis algorithms, which I have used to observe and analyze the real space dynamics of the mitotic spindle in budding yeast. The software can locate structures in three spatial dimensions and track their movement in time. By selecting fluorescent proteins which specifically label the spindle poles and cell periphery, mitotic spindle dynamics have been measured in a coordinate system relevant to the cell division. I describe how I have characterised the accuracy and precision of the algorithms by simulating fluorescence data for both spindle poles and the budding yeast cell surface. In this thesis I also describe the construction of a microfluidic apparatus that allows for the measurement of long time-scale dynamics of individual cells and the development of a cell population. The tools developed in this thesis work will facilitate in-depth quantitative analysis of the non-equilibrium processes in living cells.

  1. Coordinated weather balloon solar radiation measurements during a solar eclipse.

    PubMed

    Harrison, R G; Marlton, G J; Williams, P D; Nicoll, K A

    2016-09-28

    Solar eclipses provide a rapidly changing solar radiation environment. These changes can be studied using simple photodiode sensors, if the radiation reaching the sensors is unaffected by cloud. Transporting the sensors aloft using standard meteorological instrument packages modified to carry extra sensors, provides one promising but hitherto unexploited possibility for making solar eclipse radiation measurements. For the 20 March 2015 solar eclipse, a coordinated campaign of balloon-carried solar radiation measurements was undertaken from Reading (51.44°N, 0.94°W), Lerwick (60.15°N, 1.13°W) and Reykjavik (64.13°N, 21.90°W), straddling the path of the eclipse. The balloons reached sufficient altitude at the eclipse time for eclipse-induced variations in solar radiation and solar limb darkening to be measured above cloud. Because the sensor platforms were free to swing, techniques have been evaluated to correct the measurements for their changing orientation. In the swing-averaged technique, the mean value across a set of swings was used to approximate the radiation falling on a horizontal surface; in the swing-maximum technique, the direct beam was estimated by assuming that the maximum solar radiation during a swing occurs when the photodiode sensing surface becomes normal to the direction of the solar beam. Both approaches, essentially independent, give values that agree with theoretical expectations for the eclipse-induced radiation changes.This article is part of the themed issue 'Atmospheric effects of solar eclipses stimulated by the 2015 UK eclipse'. PMID:27550757

  2. Coordinated weather balloon solar radiation measurements during a solar eclipse

    PubMed Central

    2016-01-01

    Solar eclipses provide a rapidly changing solar radiation environment. These changes can be studied using simple photodiode sensors, if the radiation reaching the sensors is unaffected by cloud. Transporting the sensors aloft using standard meteorological instrument packages modified to carry extra sensors, provides one promising but hitherto unexploited possibility for making solar eclipse radiation measurements. For the 20 March 2015 solar eclipse, a coordinated campaign of balloon-carried solar radiation measurements was undertaken from Reading (51.44°N, 0.94°W), Lerwick (60.15°N, 1.13°W) and Reykjavik (64.13°N, 21.90°W), straddling the path of the eclipse. The balloons reached sufficient altitude at the eclipse time for eclipse-induced variations in solar radiation and solar limb darkening to be measured above cloud. Because the sensor platforms were free to swing, techniques have been evaluated to correct the measurements for their changing orientation. In the swing-averaged technique, the mean value across a set of swings was used to approximate the radiation falling on a horizontal surface; in the swing-maximum technique, the direct beam was estimated by assuming that the maximum solar radiation during a swing occurs when the photodiode sensing surface becomes normal to the direction of the solar beam. Both approaches, essentially independent, give values that agree with theoretical expectations for the eclipse-induced radiation changes. This article is part of the themed issue ‘Atmospheric effects of solar eclipses stimulated by the 2015 UK eclipse’. PMID:27550757

  3. Coordinated weather balloon solar radiation measurements during a solar eclipse.

    PubMed

    Harrison, R G; Marlton, G J; Williams, P D; Nicoll, K A

    2016-09-28

    Solar eclipses provide a rapidly changing solar radiation environment. These changes can be studied using simple photodiode sensors, if the radiation reaching the sensors is unaffected by cloud. Transporting the sensors aloft using standard meteorological instrument packages modified to carry extra sensors, provides one promising but hitherto unexploited possibility for making solar eclipse radiation measurements. For the 20 March 2015 solar eclipse, a coordinated campaign of balloon-carried solar radiation measurements was undertaken from Reading (51.44°N, 0.94°W), Lerwick (60.15°N, 1.13°W) and Reykjavik (64.13°N, 21.90°W), straddling the path of the eclipse. The balloons reached sufficient altitude at the eclipse time for eclipse-induced variations in solar radiation and solar limb darkening to be measured above cloud. Because the sensor platforms were free to swing, techniques have been evaluated to correct the measurements for their changing orientation. In the swing-averaged technique, the mean value across a set of swings was used to approximate the radiation falling on a horizontal surface; in the swing-maximum technique, the direct beam was estimated by assuming that the maximum solar radiation during a swing occurs when the photodiode sensing surface becomes normal to the direction of the solar beam. Both approaches, essentially independent, give values that agree with theoretical expectations for the eclipse-induced radiation changes.This article is part of the themed issue 'Atmospheric effects of solar eclipses stimulated by the 2015 UK eclipse'.

  4. [Coordination among healthcare levels: systematization of tools and measures].

    PubMed

    Terraza Núñez, Rebeca; Vargas Lorenzo, Ingrid; Vázquez Navarrete, María Luisa

    2006-01-01

    Improving healthcare coordination is a priority in many healthcare systems, particularly in chronic health problems in which a number of professionals and services intervene. There is an abundance of coordination strategies and mechanisms that should be systematized so that they can be used in the most appropriate context. The present article aims to analyse healthcare coordination and its instruments using the organisational theory. Coordination mechanisms can be classified according to two basic processes used to coordinate activities: programming and feedback. The optimal combination of mechanisms will depend on three factors: the degree to which healthcare activities are differentiated, the volume and type of interdependencies, and the level of uncertainty. Historically, healthcare services have based coordination on skills standardization and, most recently, on processes standardization, through clinical guidelines, maps, and plans. Their utilisation is unsatisfactory in chronic diseases involving intervention by several professionals with reciprocal interdependencies, variability in patients' response to medical interventions, and a large volume of information to be processed. In this case, mechanisms based on feedback, such as working groups, linking professionals and vertical information systems, are more effective. To date, evaluation of healthcare coordination has not been conducted systematically, using structure, process and results indicators. The different strategies and instruments have been applied mainly to long-term care and mental health and one of the challenges to healthcare coordination is to extend and evaluate their use throughout the healthcare continuum.

  5. Measurement of large aspherical mirrors using coordinate measurement machine during the grinding process

    NASA Astrophysics Data System (ADS)

    Jing, Hongwei; Kuang, Long; Fan, Tianquan; Cao, Xuedong

    2006-02-01

    A new method has been developed to measure large aspherical mirrors accurately, quickly, and economically by using CMM (coordinate measurement machine). By using CMM to get the 3D coordinates of the actual points on the large aspherical mirrors and make bestfitting of actual surface and nominal surface, we can evaluate the surface of the large aspherical mirrors. It costs only 2 hours to measure an aspherical mirror with diameter larger than 1000mm. The results show good agreement with the results measured by Hartmann-Shack interferometer. Using this method, we can supervise the profile error to less than 5 μm PV during the grinding process. All the aspherical mirrors with dimensions within the range of the machine can be measured.

  6. Organization of postural coordination patterns as a function of scaling the surface of support dynamics.

    PubMed

    Ko, Ji-Hyun; Newell, Karl M

    2015-01-01

    The number and nature of the dynamical degrees of freedom (DFs) in postural coordination patterns was investigated as a function of practice over the continuously scaled frequency of the support surface dynamics. The modal number of dynamical DFs of the coordination pattern was reduced with practice particularly in the higher frequency conditions. The ankle-knee and knee-hip couplings were highly variable across the platform frequencies and practice. The findings show that practice and higher platform frequency both contribute to reducing the number of dynamical DFs of movement organization in compensatory postural control and that this is related to an increase in the strength of particularly the ankle and hip synergy.

  7. Chemistry of stannylene-based Lewis pairs: dynamic tin coordination switching between donor and acceptor character.

    PubMed

    Krebs, Kilian M; Freitag, Sarah; Schubert, Hartmut; Gerke, Birgit; Pöttgen, Rainer; Wesemann, Lars

    2015-03-16

    The coordination chemistry of cyclic stannylene-based intramolecular Lewis pairs is presented. The P→Sn adducts were treated with [Ni(COD)2] and [Pd(PCy3)2] (COD = 1,5-cyclooctadiene, PCy3 = tricyclohexylphosphine). In the isolated coordination compounds the stannylene moiety acts either as an acceptor or a donor ligand. Examples of a dynamic switch between these two coordination modes of the P-Sn ligand are illustrated and the structures in the solid state together with heteronuclear NMR spectroscopic findings are discussed. In the case of a Ni(0) complex, (119)Sn Mössbauer spectroscopy of the uncoordinated and coordinated phosphastannirane ligand is presented.

  8. Bio-Inspired Metal-Coordination Dynamics: A Unique Tool for Engineering Soft Matter Mechanics

    NASA Astrophysics Data System (ADS)

    Holten-Andersen, Niels

    Growing evidence supports a critical role of metal-coordination in soft biological material properties such as self-healing, underwater adhesion and autonomous wound plugging. Using bio-inspired metal-binding polymers, initial efforts to mimic these properties with metal-coordination crosslinked polymer materials have shown promise. In addition, with polymer network mechanics strongly coupled to coordinate crosslink dynamics material properties can be easily tuned from visco-elastic fluids to solids. Given their exploitation in desirable material applications in Nature, bio-inspired metal-coordinate complex crosslinking provides an opportunity to further advance synthetic polymer materials design. Early lessons from this pursuit are presented.

  9. Application of the Absolute Nodal Co-Ordinate Formulation to Multibody System Dynamics

    NASA Astrophysics Data System (ADS)

    Escalona, J. L.; Hussien, H. A.; Shabana, A. A.

    1998-07-01

    The floating frame of reference formulation is currently the most widely used approach in flexible multibody simulations. The use of this approach, however, has been limited to small deformation problems. In this investigation, the computer implementation of the newabsolute nodal co-ordinate formulationand its use in the small and large deformation analysis of flexible multibody systems that consist of interconnected bodies are discussed. While in the floating frame of reference formulation a mixed set of absolute reference and local elastic co-ordinates are used, in the absolute nodal co-ordinate formulation only absolute co-ordinates are used. In the absolute nodal co-ordinate formulation, new interpretation of the nodal co-ordinates of the finite elements is used. No infinitesimal or finite rotations are used as nodal co-ordinates from beams and plates, instead, global slopes are used to define the element nodal co-ordinates. Using this interpretation of the element co-ordinates, beams and plates can be considered as isoparametric elements, and as a result, exact modelling of the rigid body dynamics can be obtained using the element shape function and the absolute nodal co-ordinates. Unlike the floating frame of reference approach, no co-ordinate transformation is required in order to determine the element inertia. The mass matrix of the finite elements is a constant matrix, and therefore, the centrifugal and Coriolis forces are equal to zero when the absolute nodal co-ordinate formulation is used. Another advantage of using the absolute nodal co-ordinate formulation in the dynamic simulation of multibody systems is its simplicity in imposing some of the joint constraints and also its simplicity in formulating the generalized forces due to spring-damper elements. The results obtained in this investigation show an excellent agreement with the results obtained using the floating frame of reference formulation when large rotation-small deformation problems are

  10. Prediction-driven coordination of distributed MPC controllers for linear unconstrained dynamic systems

    NASA Astrophysics Data System (ADS)

    Marcos, Natalia I.; Fraser Forbes, J.; Guay, Martin

    2014-08-01

    In this paper, a coordinated-distributed model predictive control (CDMPC) scheme is proposed for discrete-time, linear, unconstrained dynamic systems. The proposed control scheme incorporates a coordinator that communicates with local CDMPC controllers. With the assistance of the coordinator, the local CDMPC controllers adjust their calculated control actions iteratively to achieve the optimal plant-wide operation. A 'prediction-driven' algorithm is used to coordinate the local CDMPC controllers. Convergence of the prediction-driven algorithm is shown along with a stability analysis of the closed-loop system under coordinated-distributed control. A simulation example is used to illustrate the effectiveness of the proposed coordinated-distributed control scheme.

  11. A simple procedure to include a free-form measurement capability to standard coordinate measurement machines

    NASA Astrophysics Data System (ADS)

    Schneider, Florian; Rascher, Rolf; Stamp, Richard; Smith, Gordon

    2013-09-01

    The modern optical industry requires objects with complex topographical structures. Free-form shaped objects are of large interest in many branches, especially for size reduced, modern lifestyle products like digital cameras. State of the art multi-axes-coordinate measurement machines (CMM), like the topographical measurement machine TII-3D, are by principle suitable to measure free-form shaped objects. The only limitation is the software package. This paper may illustrate a simple way to enhance coordinate measurement machines in order to add a free-form function. Next to a coordinate measurement machine, only a state of the art CAD† system and a simple piece of software are necessary. For this paper, the CAD software CREO‡ had been used. CREO enables the user to develop a 3D object in two different ways. With the first method, the user might design the shape by drawing one or more 2D sketches and put an envelope around. Using the second method, the user could define one or more formulas in the editor to describe the favoured surface. Both procedures lead to the required three-dimensional shape. However, further features of CREO enable the user to export the XYZ-coordinates of the created surface. A special designed software tool, developed with Matlab§, converts the XYZ-file into a measurement matrix which can be used as a reference file. Finally the result of the free-form measurement, carried out with a CMM, has to be loaded into the software tool and both files will be computed. The result is an error profile which provides the deviation between the measurement and the target-geometry.

  12. The role of general dynamic coordination in the handwriting skills of children

    PubMed Central

    Scordella, Andrea; Di Sano, Sergio; Aureli, Tiziana; Cerratti, Paola; Verratti, Vittore; Fanò-Illic, Giorgio; Pietrangelo, Tiziana

    2015-01-01

    Difficulties in handwriting are often reported in children with developmental coordination disorder, and they represent an important element in the diagnosis. The present study was aimed at investigating the relation between motor coordination and handwriting skills, and to identify differences in handwriting between children without and with coordination difficulties. In particular, we asked whether visual–spatial skills have a role as mediating variables between motor coordination and handwriting. We assessed motor coordination as well as graphic abilities in children aged 7–10 years. Moreover, we evaluated their visual–motor integration, visual–spatial skills, and other cognitive abilities (memory and planning). We found no relation between motor coordination and handwriting skills, while visual–spatial skills (measured by a visual-constructive task) were related with both. Our conclusion is that visual–spatial skills are involved both in general motor coordination and in handwriting, but the relationship involves different aspects in the two cases. PMID:25999893

  13. Imperfection and Thickness Measurement of Panels Using a Coordinate Measurement Machine

    NASA Technical Reports Server (NTRS)

    Thornburgh, Robert P.

    2006-01-01

    This paper summarizes the methodology used to measure imperfection and thickness variation for flat and curved panels using a Coordinate Measurement Machine (CMM) and the software program MeasPanel. The objective is to provide a reference document so that someone with a basic understanding of CMM operation can measure a panel with minimal training. Detailed information about both the measurement system setup and computer software is provided. Information is also provided about the format of the raw data, as well as how it is post-processed for use in finite-element analysis.

  14. Evaluation of an optical coordinate measuring machine for measuring grated structures

    NASA Astrophysics Data System (ADS)

    Mares, Ancuta I.; Bergmans, Rob H.

    2012-09-01

    The use of optical coordinate measuring machines (CMMs) in industrial metrology shows great potential due to a high measurement speed and non-contact working principle. However, at present measurements performed by different users present too large variations. The uncertainty contributions are difficult to quantify and standard uncertainty evaluation procedures are needed. In order to address this issue, we have investigated the uncertainty sources of commercial optical CMMs. We present a comparison on chessboard standards between three different vision systems. The influence of critical measurement parameters on image formation and analysis is discussed.

  15. Stochastic evolutionary dynamics in minimum-effort coordination games

    NASA Astrophysics Data System (ADS)

    Li, Kun; Cong, Rui; Wang, Long

    2016-08-01

    The minimum-effort coordination game draws recently more attention for the fact that human behavior in this social dilemma is often inconsistent with the predictions of classical game theory. Here, we combine evolutionary game theory and coalescence theory to investigate this game in finite populations. Both analytic results and individual-based simulations show that effort costs play a key role in the evolution of contribution levels, which is in good agreement with those observed experimentally. Besides well-mixed populations, set structured populations have also been taken into consideration. Therein we find that large number of sets and moderate migration rate greatly promote effort levels, especially for high effort costs.

  16. Incorporating coordination dynamics into an evolutionarily grounded science of intentional change.

    PubMed

    Kostrubiec, Viviane; Kelso, J A Scott

    2014-08-01

    We suggest the authors' endeavor toward a science of intentional change may benefit from recent advances in informationally meaningful self-organizing dynamical systems. Coordination Dynamics, having contributed to an understanding of behavior on several time scales - adaptation, learning, and development - and on different levels of analysis, from the neural to the social, may complement, if not enhance, the authors' insights. PMID:25162873

  17. Mg2+ coordinating dynamics in Mg:ATP fueled motor proteins

    NASA Astrophysics Data System (ADS)

    Bojovschi, A.; Liu, Ming S.; Sadus, Richard J.

    2014-03-01

    The coordination of Mg2+ with the triphosphate group of adenosine triphosphate (ATP) in motor proteins is investigated using data mining and molecular dynamics. The possible coordination structures available from crystal data for actin, myosin, RNA polymerase, DNA polymerase, DNA helicase, and F1-ATPase are verified and investigated further by molecular dynamics. Coordination states are evaluated using structural analysis and quantified by radial distribution functions, coordination numbers, and pair interaction energy calculations. The results reveal a diverse range of both transitory and stable coordination arrangements between Mg2+ and ATP. The two most stable coordinating states occur when Mg2+ coordinates two or three oxygens from the triphosphate group of ATP. Evidence for five-site coordination is also reported involving water in addition to the triphosphate group. The stable states correspond to a pair interaction energy of either ˜-2750 kJ/mol or -3500 kJ/mol. The role of water molecules in the hydration shell surrounding Mg2+ is also reported.

  18. Equations of nonlinear dynamics of elastic shells in cylindrical Eulerian coordinates

    NASA Astrophysics Data System (ADS)

    Zubov, L. M.

    2016-05-01

    The equations of dynamics of elastic shells subjected to large deformations are formulated. The Eulerian coordinates on a circular cylinder and time are accepted as independent variables, and one of the unknown functions is the distance from a point of the shell surface to the cylinder axis. The equations of dynamics of nonlinearly elastic shells in the Eulerian coordinates are convenient for exact formulation of the problem on the interaction of strongly deformable shells with moving fluids and gases. The equations obtained can be used for dynamic calculations of fluids and gases flowings in pipelines, blood vessels, hoses, and other nonlinearly deformable thin-walled tubular elements of constructions.

  19. Approximating high-dimensional dynamics by barycentric coordinates with linear programming

    SciTech Connect

    Hirata, Yoshito Aihara, Kazuyuki; Suzuki, Hideyuki; Shiro, Masanori; Takahashi, Nozomu; Mas, Paloma

    2015-01-15

    The increasing development of novel methods and techniques facilitates the measurement of high-dimensional time series but challenges our ability for accurate modeling and predictions. The use of a general mathematical model requires the inclusion of many parameters, which are difficult to be fitted for relatively short high-dimensional time series observed. Here, we propose a novel method to accurately model a high-dimensional time series. Our method extends the barycentric coordinates to high-dimensional phase space by employing linear programming, and allowing the approximation errors explicitly. The extension helps to produce free-running time-series predictions that preserve typical topological, dynamical, and/or geometric characteristics of the underlying attractors more accurately than the radial basis function model that is widely used. The method can be broadly applied, from helping to improve weather forecasting, to creating electronic instruments that sound more natural, and to comprehensively understanding complex biological data.

  20. On perturbation and pattern coexistence in postural coordination dynamics.

    PubMed

    Bardy, Benoît G; Oullier, Olivier; Lagarde, Julien; Stoffregen, Thomas A

    2007-07-01

    In studies of postural control, investigators have used either experimentally induced perturbations to stance or unperturbed stance. The distinction between perturbed and unperturbed stance has gained renewed importance in the context of inphase and antiphase coordination of the hips and ankles. Several contributions have replicated the findings published over the past decade, suggesting the possibility of a unified view of postural control. However, any proposed unified view depends on how so called perturbed and unperturbed are defined. The authors argue that, to date, there is no explicit and general definition of those terms. The main reason is that all perturbations are relative and depend on appropriate frames of reference for perception and action. Arguments about empirical or theoretical unification of perturbed and unperturbed stance are premature.

  1. General Tortoise Coordinate Transformation in a Dynamical Kerr-Newman Black Hole

    NASA Astrophysics Data System (ADS)

    Liu, Xian-Ming; Cheng, Su-Jun; Liu, Wen-Biao

    2012-02-01

    Under the extended dynamical tortoise coordinate transformation, Damour-Ruffini method has been applied to calculate the charged particles' Hawking radiation from the apparent horizon of a dynamical Kerr-Newman black hole. It is shown that Hawking radiation is still purely thermal black body spectrum. Moreover, the temperature of Hawking radiation is corresponding to the apparent horizon surface gravity and the first law of thermodynamics can also be constructed successfully on the apparent horizon in the dynamical Kerr-Newman black hole.

  2. Dynamic Coordination Of A Two-Arm Robotic Manipulator

    NASA Technical Reports Server (NTRS)

    Lee, Sukhan; Kim, Sungbok

    1994-01-01

    Report presents study of dynamical and kinematical considerations guiding selection of configuration of self-reconfigurable, two-arm robotic manipulator. Two multiple-link arms cooperate in manipulating single object, reconfiguring their mutual, cooperative structure according to changing task requirements.

  3. A vision-aided alignment datum system for coordinate measuring machines

    NASA Astrophysics Data System (ADS)

    Wang, L.; Lin, G. C. I.

    1997-07-01

    This paper presents the development of a CAD-based and vision-aided precision measurement system. A new coordinate system alignment technique for coordinate measuring machines (CMMs) is described. This alignment technique involves a machine vision system with CAD-based planning and execution of inspection. The determination method for measuring datums for the coordinate measuring technique, using the AutoCAD development system, is described in more detail. To improve image quality in the machine vision system, a contrast enhancement technique is used on the image background to reduce image noise, and an on-line calibration technique is applied. Some systematic errors may be caused by imperfect geometric features in components during coordinate system alignment. This measurement system approach, with its new measuring coordinate alignment method, can be used for high-precision measurement to overcome such errors.

  4. Dynamic indocyanine green angiography measurements

    NASA Astrophysics Data System (ADS)

    Holmes, Timothy; Invernizzi, Alessandro; Larkin, Sean; Staurenghi, Giovanni

    2012-11-01

    Dynamic indocyanine green imaging uses a scanning laser ophthalmoscope and a fluorescent dye to produce movies of the dye-filling pattern in the retina and choroid of the eye. It is used for evaluating choroidal neovascularization. Movies are examined to identify the anatomy of the pathology for planning treatment and to evaluate progression or response to treatment. The popularity of this approach is affected by the complexity and difficulty in interpreting the movies. Software algorithms were developed to produce images from the movies that are easy to interpret. A mathematical model is formulated of the flow dynamics, and a fitting algorithm is designed that solves for the flow parameters. The images provide information about flow and perfusion, including regions of change between examinations. Imaged measures include the dye fill-time, temporal dispersion, and magnitude of the dye dilution temporal curves associated with image pixels. Cases show how the software can help to identify clinically relevant anatomy such as feeder vessels, drain vessels, capillary networks, and normal choroidal draining vessels. As a potential tool for research into the character of neovascular conditions and treatments, it reveals the flow dynamics and character of the lesion. Future varieties of this methodology may be used for evaluating the success of engineered tissue transplants, surgical flaps, reconstructive surgery, breast surgery, and many other surgical applications where flow, perfusion, and vascularity of tissue are important.

  5. Biomechanics and muscle coordination of human walking. Part I: introduction to concepts, power transfer, dynamics and simulations.

    PubMed

    Zajac, Felix E; Neptune, Richard R; Kautz, Steven A

    2002-12-01

    Current understanding of how muscles coordinate walking in humans is derived from analyses of body motion, ground reaction force and EMG measurements. This is Part I of a two-part review that emphasizes how muscle-driven dynamics-based simulations assist in the understanding of individual muscle function in walking, especially the causal relationships between muscle force generation and walking kinematics and kinetics. Part I reviews the strengths and limitations of Newton-Euler inverse dynamics and dynamical simulations, including the ability of each to find the contributions of individual muscles to the acceleration/deceleration of the body segments. We caution against using the concept of biarticular muscles transferring power from one joint to another to infer muscle coordination principles because energy flow among segments, even the adjacent segments associated with the joints, cannot be inferred from computation of joint powers and segmental angular velocities alone. Rather, we encourage the use of dynamical simulations to perform muscle-induced segmental acceleration and power analyses. Such analyses have shown that the exchange of segmental energy caused by the forces or accelerations induced by a muscle can be fundamentally invariant to whether the muscle is shortening, lengthening, or neither. How simulation analyses lead to understanding the coordination of seated pedaling, rather than walking, is discussed in this first part because the dynamics of pedaling are much simpler, allowing important concepts to be revealed. We elucidate how energy produced by muscles is delivered to the crank through the synergistic action of other non-energy producing muscles; specifically, that a major function performed by a muscle arises from the instantaneous segmental accelerations and redistribution of segmental energy throughout the body caused by its force generation. Part II reviews how dynamical simulations provide insight into muscle coordination of walking.

  6. Calculating uncertainty of 1-D measurements on a coordinate measuring machine

    SciTech Connect

    Zurcher, N.

    1995-01-01

    This presentation is a quick review of the actions taken to calculate the uncertainty of measurements made along one axis of the M-60 Coordinate Measuring Machine (CMM). National Institute of Standards and Technology (NIST) Technical Note 1297 `Guidelines for Evaluating the Uncertainty of NIST Measurement Results`, was used as a guide to define what actions would be taken. Very simply stated, TN 1297 says that the uncertainty of a measurement result consists of a combination of several components (sources of variation) in the measuring process. The basic approach is to represent each component of uncertainty by an estimated standard deviation. These standard deviations are then combined by the `root-sum-of-squares` technique to arrive at the estimated standard deviation of the measurement result.

  7. Measuring large aspherics using a commercially available 3D-coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Otto, Wolfgang; Matthes, Axel; Schiehle, Heinz

    2000-07-01

    A CNC-controlled precision measuring machine is a very powerful tool in the optical shop not only to determine the surface figure, but also to qualify the radius of curvature and conic constant of aspherics. We used a commercially available 3D-coordinate measuring machine (CMM, ZEISS UPMC 850 CARAT S-ACC) to measure the shape of the GEMINI 1-m convex secondary mirrors at different lapping and polishing stages. To determine the measuring accuracy we compared the mechanical measurements with the results achieved by means of an interferometrical test setup. The data obtained in an early stage of polishing were evaluated in Zernike polynomials which show a very good agreement. The deviation concerning long wave rotational symmetrical errors was 20 nm rms, whereas the accuracy measuring of mid spatial frequency deviations was limited to about 100 nm rms.

  8. Deployment dynamics of a simplified spinning IKAROS solar sail via absolute coordinate based method

    NASA Astrophysics Data System (ADS)

    Zhao, Jiang; Tian, Qiang; Hu, Hai-Yan

    2013-02-01

    The spinning solar sail of large scale has been well developed in recent years. Such a solar sail can be considered as a rigid-flexible multibody system mainly composed of a spinning central rigid hub, a number of flexible thin tethers, sail membranes, and tip masses. A simplified interplanetary kite-craft accelerated by radiation of the Sun (IKAROS) model is established in this study by using the absolute-coordinate-based (ACB) method that combines the natural coordinate formulation (NCF) describing the central rigid hub and the absolute nodal coordinate formulation (ANCF) describing flexible parts. The initial configuration of the system in the second-stage deployment is determined through both dynamic and static analyses. The huge set of stiff equations of system dynamics is solved by using the generalized-alpha method, and thus the deployment dynamics of the system can be well understood.

  9. Dynamic Models and Coordination Analysis of Reverse Supply Chain with Remanufacturing

    NASA Astrophysics Data System (ADS)

    Yan, Nina

    In this paper, we establish a reverse chain system with one manufacturer and one retailer under demand uncertainties. Distinguishing between the recycling process of the retailer and the remanufacturing process of the manufacturer, we formulate a two-stage dynamic model for reverse supply chain based on remanufacturing. Using buyback contract as coordination mechanism and applying dynamic programming the optimal decision problems for each stage are analyzed. It concluded that the reverse supply chain system could be coordinated under the given condition. Finally, we carry out numerical calculations to analyze the expected profits for the manufacturer and the retailer under different recovery rates and recovery prices and the outcomes validate the theoretical analyses.

  10. Coordination dynamics in a socially situated nervous system.

    PubMed

    Coey, Charles A; Varlet, Manuel; Richardson, Michael J

    2012-01-01

    Traditional theories of cognitive science have typically accounted for the organization of human behavior by detailing requisite computational/representational functions and identifying neurological mechanisms that might perform these functions. Put simply, such approaches hold that neural activity causes behavior. This same general framework has been extended to accounts of human social behavior via concepts such as "common-coding" and "co-representation" and much recent neurological research has been devoted to brain structures that might execute these social-cognitive functions. Although these neural processes are unquestionably involved in the organization and control of human social interactions, there is good reason to question whether they should be accorded explanatory primacy. Alternatively, we propose that a full appreciation of the role of neural processes in social interactions requires appropriately situating them in their context of embodied-embedded constraints. To this end, we introduce concepts from dynamical systems theory and review research demonstrating that the organization of human behavior, including social behavior, can be accounted for in terms of self-organizing processes and lawful dynamics of animal-environment systems. Ultimately, we hope that these alternative concepts can complement the recent advances in cognitive neuroscience and thereby provide opportunities to develop a complete and coherent account of human social interaction.

  11. Coordinated DNA dynamics during the human telomerase catalytic cycle

    NASA Astrophysics Data System (ADS)

    Parks, Joseph W.; Stone, Michael D.

    2014-06-01

    The human telomerase reverse transcriptase (hTERT) utilizes a template within the integral RNA subunit (hTR) to direct extension of telomeres. Telomerase exhibits repeat addition processivity (RAP) and must therefore translocate the nascent DNA product into a new RNA:DNA hybrid register to prime each round of telomere repeat synthesis. Here, we use single-molecule FRET and nuclease protection assays to monitor telomere DNA structure and dynamics during the telomerase catalytic cycle. DNA translocation during RAP proceeds through a previously uncharacterized kinetic substep during which the 3‧-end of the DNA substrate base pairs downstream within the hTR template. The rate constant for DNA primer realignment reveals this step is not rate limiting for RAP, suggesting a second slow conformational change repositions the RNA:DNA hybrid into the telomerase active site and drives the extrusion of the 5‧-end of the DNA primer out of the enzyme complex.

  12. Single camera stereo vision coordinate measurement in parts pose recognization on CMM

    NASA Astrophysics Data System (ADS)

    Wang, Chun-mei; Huang, Feng-shan; Wang, Xue-sha; Chen, Li

    2014-11-01

    In order to recognize parts' pose on Coordinate Measuring Machine (CMM) correctly and fast, based on the translation of CMM, A single camera stereo vision measurement method for feature points' 3D coordinate on the measured parts is proposed. According to the double cameras stereo vision principle, a image of the part to be measured is captured by A CCD camera, which is driven by CMM along its X or Y axis, on two different position correspondly. Thus, the part's single camera stereo vision measurement is realized with the proposed image matching method, which is based on the centroid offset of image edge, on two images of the same feature point on the part, and each feature point's 3D coordinate in the camera coordinate system can be obtained. The measuring system is set up, and the experiment is conducted. The feature point's coordinate measuring time is 1.818s, and the difference value, which is between feature points' 3D coordinate calculated with the experiment result and that measured by CMM in the machine coordinate system, is less than 0.3mm. This measuring result can meet parts' pose real-time recognization requirement on the intelligent CMM, and also show that the method proposed in this paper is feasible.

  13. Changes in dynamic balance control over time in children with and without Developmental Coordination Disorder.

    PubMed

    Jelsma, L D; Smits-Engelsman, B C M; Krijnen, W P; Geuze, R H

    2016-10-01

    The aim of this study was to examine differences in underlying adaptations of dynamic balance in children with and without Developmental Coordination Disorder (DCD) during a Wii Fit game and to measure changes over time and after intervention. Twenty-eight children with DCD and 21 typically developing (TD) children participated in the study. Analyses of force plate variables showed that the TD group initially used a longer path length for the ski slope descent and tended toward more variation in Center of Pressure (CoP) displacement in lateral direction than the children with DCD. In contrast, the TD group showed a trend of fewer reversals per cm in both AP and lateral direction. After the nonintervention period, the TD group improved performance by decreasing the path length, while the DCD group improved by increasing the path length and by decreasing the number of reversals. After intervention, no changes were found in sway characteristics. Individual analyses within the DCD group showed that the path length per run fell more often within the 95% confidence Interval of the faultless runs. In conclusion both TD and DCD children modify the underlying kinetics of dynamic balance control, but in different ways and both lead to better performance.

  14. Changes in dynamic balance control over time in children with and without Developmental Coordination Disorder.

    PubMed

    Jelsma, L D; Smits-Engelsman, B C M; Krijnen, W P; Geuze, R H

    2016-10-01

    The aim of this study was to examine differences in underlying adaptations of dynamic balance in children with and without Developmental Coordination Disorder (DCD) during a Wii Fit game and to measure changes over time and after intervention. Twenty-eight children with DCD and 21 typically developing (TD) children participated in the study. Analyses of force plate variables showed that the TD group initially used a longer path length for the ski slope descent and tended toward more variation in Center of Pressure (CoP) displacement in lateral direction than the children with DCD. In contrast, the TD group showed a trend of fewer reversals per cm in both AP and lateral direction. After the nonintervention period, the TD group improved performance by decreasing the path length, while the DCD group improved by increasing the path length and by decreasing the number of reversals. After intervention, no changes were found in sway characteristics. Individual analyses within the DCD group showed that the path length per run fell more often within the 95% confidence Interval of the faultless runs. In conclusion both TD and DCD children modify the underlying kinetics of dynamic balance control, but in different ways and both lead to better performance. PMID:27404396

  15. Exact dynamics of stochastic linear delayed systems: Application to spatiotemporal coordination of comoving agents

    NASA Astrophysics Data System (ADS)

    McKetterick, Thomas John; Giuggioli, Luca

    2014-10-01

    Delayed dynamics result from finite transmission speeds of a signal in the form of energy, mass, or information. In stochastic systems the resulting lagged dynamics challenge our understanding due to the rich behavioral repertoire encompassing monotonic, oscillatory, and unstable evolution. Despite the vast literature, quantifying this rich behavior is limited by a lack of explicit analytic studies of high-dimensional stochastic delay systems. Here we fill this gap for systems governed by a linear Langevin equation of any number of delays and spatial dimensions with additive Gaussian noise. By exploiting Laplace transforms we are able to derive an exact time-dependent analytic solution of the Langevin equation. By using characteristic functionals we are able to construct the full time dependence of the multivariate probability distribution of the stochastic process as a function of the delayed and nondelayed random variables. As an application we consider interactions in animal collective movement that go beyond the traditional assumption of instantaneous alignment. We propose models for coordinated maneuvers of comoving agents applicable to recent empirical findings in pigeons and bats whereby individuals copy the heading of their neighbors with some delay. We highlight possible strategies that individual pairs may adopt to reduce the variance in their velocity difference and/or in their spatial separation. We also show that a minimum in the variance of the spatial separation at long times can be achieved with certain ratios of measurement to reaction delay.

  16. Coordinated Dynamics of RNA Splicing Speckles in the Nucleus.

    PubMed

    Zhang, Qiao; Kota, Krishna P; Alam, Samer G; Nickerson, Jeffrey A; Dickinson, Richard B; Lele, Tanmay P

    2016-06-01

    Despite being densely packed with chromatin, nuclear bodies and a nucleoskeletal network, the nucleus is a remarkably dynamic organelle. Chromatin loops form and relax, RNA transcripts and transcription factors move diffusively, and nuclear bodies move. We show here that RNA splicing speckled domains (splicing speckles) fluctuate in constrained nuclear volumes and remodel their shapes. Small speckles move in a directed way toward larger speckles with which they fuse. This directed movement is reduced upon decreasing cellular ATP levels or inhibiting RNA polymerase II activity. The random movement of speckles is reduced upon decreasing cellular ATP levels, moderately reduced after inhibition of SWI/SNF chromatin remodeling and modestly increased upon inhibiting RNA polymerase II activity. To define the paths through which speckles can translocate in the nucleus, we generated a pressure gradient to create flows in the nucleus. In response to the pressure gradient, speckles moved along curvilinear paths in the nucleus. Collectively, our results demonstrate a new type of ATP-dependent motion in the nucleus. We present a model where recycling splicing factors return as part of small sub-speckles from distal sites of RNA processing to larger splicing speckles by a directed ATP-driven mechanism through interchromatin spaces.

  17. Milking the spherical cow - on aspherical dynamics in spherical coordinates

    NASA Astrophysics Data System (ADS)

    Pontzen, Andrew; Read, Justin I.; Teyssier, Romain; Governato, Fabio; Gualandris, Alessia; Roth, Nina; Devriendt, Julien

    2015-08-01

    Galaxies and the dark matter haloes that host them are not spherically symmetric, yet spherical symmetry is a helpful simplifying approximation for idealized calculations and analysis of observational data. The assumption leads to an exact conservation of angular momentum for every particle, making the dynamics unrealistic. But how much does that inaccuracy matter in practice for analyses of stellar distribution functions, collisionless relaxation, or dark matter core-creation? We provide a general answer to this question for a wide class of aspherical systems; specifically, we consider distribution functions that are `maximally stable', i.e. that do not evolve at first order when external potentials (which arise from baryons, large-scale tidal fields or infalling substructure) are applied. We show that a spherically symmetric analysis of such systems gives rise to the false conclusion that the density of particles in phase space is ergodic (a function of energy alone). Using this idea we are able to demonstrate that: (a) observational analyses that falsely assume spherical symmetry are made more accurate by imposing a strong prior preference for near-isotropic velocity dispersions in the centre of spheroids; (b) numerical simulations that use an idealized spherically symmetric setup can yield misleading results and should be avoided where possible; and (c) triaxial dark matter haloes (formed in collisionless cosmological simulations) nearly attain our maximally stable limit, but their evolution freezes out before reaching it.

  18. Perceptuo-motor compatibility governs multisensory integration in bimanual coordination dynamics.

    PubMed

    Zelic, Gregory; Mottet, Denis; Lagarde, Julien

    2016-02-01

    The brain has the remarkable ability to bind together inputs from different sensory origin into a coherent percept. Behavioral benefits can result from such ability, e.g., a person typically responds faster and more accurately to cross-modal stimuli than to unimodal stimuli. To date, it is, however, largely unknown whether such multisensory benefits, shown for discrete reactive behaviors, generalize to the continuous coordination of movements. The present study addressed multisensory integration from the perspective of bimanual coordination dynamics, where the perceptual activity no longer triggers a single response but continuously guides the motor action. The task consisted in coordinating anti-symmetrically the continuous flexion-extension of the index fingers, while synchronizing with an external pacer. Three different configurations of metronome were tested, for which we examined whether a cross-modal pacing (audio-tactile beats) improved the stability of the coordination in comparison with unimodal pacing condition (auditory or tactile beats). We found a more stable bimanual coordination for cross-modal pacing, but only when the metronome configuration directly matched the anti-symmetric coordination pattern. We conclude that multisensory integration can benefit the continuous coordination of movements; however, this is constrained by whether the perceptual and motor activities match in space and time. PMID:26525707

  19. Perceptuo-motor compatibility governs multisensory integration in bimanual coordination dynamics.

    PubMed

    Zelic, Gregory; Mottet, Denis; Lagarde, Julien

    2016-02-01

    The brain has the remarkable ability to bind together inputs from different sensory origin into a coherent percept. Behavioral benefits can result from such ability, e.g., a person typically responds faster and more accurately to cross-modal stimuli than to unimodal stimuli. To date, it is, however, largely unknown whether such multisensory benefits, shown for discrete reactive behaviors, generalize to the continuous coordination of movements. The present study addressed multisensory integration from the perspective of bimanual coordination dynamics, where the perceptual activity no longer triggers a single response but continuously guides the motor action. The task consisted in coordinating anti-symmetrically the continuous flexion-extension of the index fingers, while synchronizing with an external pacer. Three different configurations of metronome were tested, for which we examined whether a cross-modal pacing (audio-tactile beats) improved the stability of the coordination in comparison with unimodal pacing condition (auditory or tactile beats). We found a more stable bimanual coordination for cross-modal pacing, but only when the metronome configuration directly matched the anti-symmetric coordination pattern. We conclude that multisensory integration can benefit the continuous coordination of movements; however, this is constrained by whether the perceptual and motor activities match in space and time.

  20. Tortoise coordinate and Hawking effect in a dynamical Kerr black hole

    NASA Astrophysics Data System (ADS)

    Yang, Jian; Zhao, Zheng; Liu, Wenbiao

    2011-02-01

    Hawking effect from a dynamical Kerr black hole is investigated using the improved Damour-Ruffini method with a new tortoise coordinate transformation. Hawking temperature of the black hole can be obtained point by point at the event horizon. It is found that Hawking temperatures of different points on the surface are different. Moreover, the temperature does not turn to zero while the dynamical black hole turns to an extreme one.

  1. Evolutionary dynamics of the traveler's dilemma and minimum-effort coordination games on complex networks.

    PubMed

    Iyer, Swami; Killingback, Timothy

    2014-10-01

    The traveler's dilemma game and the minimum-effort coordination game are social dilemmas that have received significant attention resulting from the fact that the predictions of classical game theory are inconsistent with the results found when the games are studied experimentally. Moreover, both the traveler's dilemma and the minimum-effort coordination games have potentially important applications in evolutionary biology. Interestingly, standard deterministic evolutionary game theory, as represented by the replicator dynamics in a well-mixed population, is also inadequate to account for the behavior observed in these games. Here we study the evolutionary dynamics of both these games in populations with interaction patterns described by a variety of complex network topologies. We investigate the evolutionary dynamics of these games through agent-based simulations on both model and empirical networks. In particular, we study the effects of network clustering and assortativity on the evolutionary dynamics of both games. In general, we show that the evolutionary behavior of the traveler's dilemma and minimum-effort coordination games on complex networks is in good agreement with that observed experimentally. Thus, formulating the traveler's dilemma and the minimum-effort coordination games on complex networks neatly resolves the paradoxical aspects of these games.

  2. Homodyne displacement measuring interferometer probe for optical coordinate measuring machine with tip and tilt sensitivity

    NASA Astrophysics Data System (ADS)

    Butler, Sam C.; Ricci, Michael A.; Wang, Chen; Wei, Qun; Ellis, Jonathan D.

    2015-10-01

    In this proceedings, we present a 3DoF (one linear, two angular) optical probe for measuring freeform optics in conjunction with an optical coordinate measuring machine (OCMM). This probe uses homodyne interferometry in a Michelson configuration and position sensing detection to simultaneously measure displacement, tip, and tilt. The goal of this work is to investigate point-to-point methods for measuring freeform optics and establish a probing methodology that can perform self-alignment with respect to the local optical surface. We present the design and preliminary benchtop validation of the probe's performance. Benchtop validation shows successful measurements with 5 nm linear and 20 μrad angular noise levels, with a 15 μm spot size. A CMOS sensor is used for visual confirmation of proper focus on measurement surface to minimize initial defocus error. A PSD detects linear horizontal and vertical displacement of the reflected beam from the measurement surface using autocollimation. In-phase and quadrature signals are measured by two photodetectors and post-processed to obtain displacement information. Periodic error caused by polarization effects and beam mixing is compensated by FPGA-based signal processing.

  3. [Coordination patterns assessed by a continuous measure of joints coupling during upper limb repetitive movements].

    PubMed

    Draicchio, F; Silvetti, A; Ranavolo, A; Iavicoli, S

    2008-01-01

    We analyzed the coordination patterns between elbow, shoulder and trunk in a motor task consisting of reaching out, picking up a cylinder, and transporting it back by using the Dynamical Systems Theory and calculating the continuous relative phase (CRP), a continuous measure of the coupling between two interacting joints. We used an optoelectronic motion analysis system consisting of eight infra-red ray cameras to detect the movements of nine skin-mounted markers. We calculated the root square of the adjusted coefficient of determination, the coefficient of multiple correlation (CMC), in order to investigate the repeatability of the joints coordination. The data confirm that the CNS establishes both synergic (i.e. coupling between shoulder and trunk on the frontal plane) and hierarchical (i.e. coupling between elbow-shoulder-trunk on the horizontal plane) relationships among the available degrees of freedom to overcome the complexity due to motor redundancy. The present study describes a method to investigate the organization of the kinematic degrees of freedom during upper limb multi-joint motor tasks that can be useful to assess upper limb repetitive movements.

  4. Estimation of measurement accuracy of track point coordinates in nuclear photoemulsion

    NASA Astrophysics Data System (ADS)

    Shamanov, V. V.

    1995-03-01

    A simple method for an estimation of the measurement accuracy of track point coordinates in nuclear photoemulsion is described. The method is based on analysis of residual deviations of measured track points from a straight line approximating the track. Reliability of the algorithm is illustrated by Monte Carlo simulation. Examples of using the method for an estimation of the accuracy of track point coordinates measured with the microscope KSM-1 (VEB Carl Zeiss Jena) are given.

  5. High-speed real-time 3-D coordinates measurement based on fringe projection profilometry considering camera lens distortion

    NASA Astrophysics Data System (ADS)

    Feng, Shijie; Chen, Qian; Zuo, Chao; Sun, Jiasong; Yu, Shi Ling

    2014-10-01

    Optical three-dimensional (3-D) profilometry is gaining increasing attention for its simplicity, flexibility, high accuracy, and non-contact nature. Recent advances in imaging sensors and digital projection technology further its progress in high-speed, real-time applications, enabling 3-D shapes reconstruction of moving objects and dynamic scenes. However, the camera lens is never perfect and the lens distortion does influence the accuracy of the measurement result, which is often overlooked in the existing real-time 3-D shape measurement systems. To this end, here we present a novel high-speed real-time 3-D coordinates measuring technique based on fringe projection with the consideration of the camera lens distortion. A pixel mapping relation between a distorted image and a corrected one is pre-determined and stored in computer memory for real-time fringe correction. The out-of-plane height is obtained firstly and the acquisition for the two corresponding in-plane coordinates follows on the basis of the solved height. Besides, a method of lookup table (LUT) is introduced as well for fast data processing. Our experimental results reveal that the measurement error of the in-plane coordinates has been reduced by one order of magnitude and the accuracy of the out-plane coordinate been tripled after the distortions being eliminated. Moreover, owing to the generated LUTs, a 3-D reconstruction speed of 92.34 frames per second can be achieved.

  6. Perioperative Care Coordination Measurement: A Tool to Support Care Integration of Pediatric Surgical Patients.

    PubMed

    Ferrari, Lynne R; Ziniel, Sonja I; Antonelli, Richard C

    2016-03-01

    The relationship of care coordination activities and outcomes to resource utilization and personnel costs has been evaluated for a number of pediatric medical home practices. One of the first tools designed to evaluate the activities and outcomes for pediatric care coordination is the Care Coordination Measurement Tool (CCMT). It has become widely used as an instrument for health care providers in both primary and subspecialty care settings. This tool enables the user to stratify patients based on acuity and complexity while documenting the activities and outcomes of care coordination. We tested the feasibility of adapting the CCMT to a pediatric surgical population at Boston Children's Hospital. The tool was used to assess the preoperative care coordination activities. Care coordination activities were tracked during the interval from the date the patient was scheduled for a surgical or interventional procedure through the day of the procedure. A care coordination encounter was defined as any task, whether face to face or not, supporting the development or implementation of a plan of care. Data were collected to enable analysis of 5675 care coordination encounters supporting the care provided to 3406 individual surgical cases (patients). The outcomes of care coordination, as documented by the preoperative nursing staff, included the elaboration of the care plan through patient-focused communication among specialist, facilities, perioperative team, and primary care physicians in 80.5% of cases. The average time spent on care coordination activities increased incrementally by 30 minutes with each additional care coordination encounter for a surgical case. Surgical cases with 1 care coordination encounter took an average of 35.7 minutes of preoperative care coordination, whereas those with ≥4 care coordination encounters reported an average of 121.6 minutes. We successfully adapted and implemented the CCMT for a pediatric surgical population and measured nonface

  7. Geometric calibration of a coordinate measuring machine using a laser tracking system

    NASA Astrophysics Data System (ADS)

    Umetsu, Kenta; Furutnani, Ryosyu; Osawa, Sonko; Takatsuji, Toshiyuki; Kurosawa, Tomizo

    2005-12-01

    This paper proposes a calibration method for a coordinate measuring machine (CMM) using a laser tracking system. The laser tracking system can measure three-dimensional coordinates based on the principle of trilateration with high accuracy and is easy to set up. The accuracy of length measurement of a single laser tracking interferometer (laser tracker) is about 0.3 µm over a length of 600 mm. In this study, we first measured 3D coordinates using the laser tracking system. Secondly, 21 geometric errors, namely, parametric errors of the CMM, were estimated by the comparison of the coordinates obtained by the laser tracking system and those obtained by the CMM. As a result, the estimated parametric errors agreed with those estimated by a ball plate measurement, which demonstrates the validity of the proposed calibration system.

  8. Symplectic integration of closed chain rigid body dynamics with internal coordinate equations of motion

    NASA Astrophysics Data System (ADS)

    Mazur, Alexey K.

    1999-07-01

    Internal coordinate molecular dynamics (ICMD) is a recent efficient method for modeling polymer molecules which treats them as chains of rigid bodies rather than ensembles of point particles as in Cartesian MD. Unfortunately, it is readily applicable only to linear or tree topologies without closed flexible loops. Important examples violating this condition are sugar rings of nucleic acids, proline residues in proteins, and also disulfide bridges. This paper presents the first complete numerical solution of the chain closure problem within the context of ICMD. The method combines natural implicit fixation of bond lengths and bond angles by the choice of internal coordinates with explicit constraints similar to Cartesian dynamics used to maintain the chain closure. It is affordable for large molecules and makes possible 3-5 times faster dynamics simulations of molecular systems with flexible rings, including important biological objects like nucleic acids and disulfide-bonded proteins.

  9. The dynamics of zinc sites in proteins: electronic basis for coordination sphere expansion at structural sites.

    PubMed

    Daniel, A Gerard; Farrell, Nicholas P

    2014-12-01

    The functional role assumed by zinc in proteins is closely tied to the variable dynamics around its coordination sphere arising by virtue of its flexibility in bonding. Modern experimental and computational methods allow the detection and study of previously unknown features of bonding between zinc and its ligands in protein environment. These discoveries are occurring just in time as novel biological functions of zinc, which involve rather unconventional coordination trends, are emerging. In this sense coordination sphere expansion of structural zinc sites, as observed in our previous experiments, is a novel phenomenon. Here we explore the electronic and structural requirements by simulating this phenomenon in structural zinc sites using DFT computations. For this purpose, we have chosen MPW1PW91 and a mixed basis set combination as the DFT method through benchmarking, because it accurately reproduces structural parameters of experimentally characterized zinc compounds. Using appropriate models, we show that the greater ionic character of zinc coordination would allow for coordination sphere expansion if the steric and electrostatic repulsions of the ligands are attenuated properly. Importantly, through the study of electronic and structural aspects of the models used, we arrive at a comprehensive bonding model, explaining the factors that influence coordination of zinc in proteins. The proposed model along with the existing knowledge would enhance our ability to predict zinc binding sites in proteins, which is today of growing importance given the predicted enormity of the zinc proteome.

  10. The Virtual Teacher (VT) Paradigm: Learning New Patterns of Interpersonal Coordination Using the Human Dynamic Clamp.

    PubMed

    Kostrubiec, Viviane; Dumas, Guillaume; Zanone, Pier-Giorgio; Kelso, J A Scott

    2015-01-01

    The Virtual Teacher paradigm, a version of the Human Dynamic Clamp (HDC), is introduced into studies of learning patterns of inter-personal coordination. Combining mathematical modeling and experimentation, we investigate how the HDC may be used as a Virtual Teacher (VT) to help humans co-produce and internalize new inter-personal coordination pattern(s). Human learners produced rhythmic finger movements whilst observing a computer-driven avatar, animated by dynamic equations stemming from the well-established Haken-Kelso-Bunz (1985) and Schöner-Kelso (1988) models of coordination. We demonstrate that the VT is successful in shifting the pattern co-produced by the VT-human system toward any value (Experiment 1) and that the VT can help humans learn unstable relative phasing patterns (Experiment 2). Using transfer entropy, we find that information flow from one partner to the other increases when VT-human coordination loses stability. This suggests that variable joint performance may actually facilitate interaction, and in the long run learning. VT appears to be a promising tool for exploring basic learning processes involved in social interaction, unraveling the dynamics of information flow between interacting partners, and providing possible rehabilitation opportunities.

  11. Patterns of Horse-Rider Coordination during Endurance Race: A Dynamical System Approach

    PubMed Central

    Viry, Sylvain; Sleimen-Malkoun, Rita; Temprado, Jean-Jacques; Frances, Jean-Philippe; Berton, Eric; Laurent, Michel; Nicol, Caroline

    2013-01-01

    In riding, most biomechanical studies have focused on the description of the horse locomotion in unridden condition. In this study, we draw the prospect of how the basic principles established in inter-personal coordination by the theory of Coordination Dynamics may provide a conceptual and methodological framework for understanding the horse-rider coupling. The recent development of mobile technologies allows combined horse and rider recordings during long lasting natural events such as endurance races. Six international horse-rider dyads were thus recorded during a 120 km race by using two tri-axial accelerometers placed on the horses and riders, respectively. The analysis concentrated on their combined vertical displacements. The obtained shapes and angles of Lissajous plots together with values of relative phase between horse and rider displacements at lower reversal point allowed us to characterize four coordination patterns, reflecting the use of two riding techniques per horse's gait (trot and canter). The present study shows that the concepts, methods and tools of self-organizing dynamic system approach offer new directions for understanding horse-rider coordination. The identification of the horse-rider coupling patterns constitutes a firm basis to further study the coalition of multiple constraints that determine their emergence and their dynamics in endurance race. PMID:23940788

  12. The Virtual Teacher (VT) Paradigm: Learning New Patterns of Interpersonal Coordination Using the Human Dynamic Clamp

    PubMed Central

    2015-01-01

    The Virtual Teacher paradigm, a version of the Human Dynamic Clamp (HDC), is introduced into studies of learning patterns of inter-personal coordination. Combining mathematical modeling and experimentation, we investigate how the HDC may be used as a Virtual Teacher (VT) to help humans co-produce and internalize new inter-personal coordination pattern(s). Human learners produced rhythmic finger movements whilst observing a computer-driven avatar, animated by dynamic equations stemming from the well-established Haken-Kelso-Bunz (1985) and Schöner-Kelso (1988) models of coordination. We demonstrate that the VT is successful in shifting the pattern co-produced by the VT-human system toward any value (Experiment 1) and that the VT can help humans learn unstable relative phasing patterns (Experiment 2). Using transfer entropy, we find that information flow from one partner to the other increases when VT-human coordination loses stability. This suggests that variable joint performance may actually facilitate interaction, and in the long run learning. VT appears to be a promising tool for exploring basic learning processes involved in social interaction, unraveling the dynamics of information flow between interacting partners, and providing possible rehabilitation opportunities. PMID:26569608

  13. Low Band Gap Coplanar Conjugated Molecules Featuring Dynamic Intramolecular Lewis Acid-Base Coordination.

    PubMed

    Zhu, Congzhi; Guo, Zi-Hao; Mu, Anthony U; Liu, Yi; Wheeler, Steven E; Fang, Lei

    2016-05-20

    Ladder-type conjugated molecules with a low band gap and low LUMO level were synthesized through an N-directed borylation reaction of pyrazine-derived donor-acceptor-donor precursors. The intramolecular boron-nitrogen coordination bonds played a key role in rendering the rigid and coplanar conformation of these molecules and their corresponding electronic structures. Experimental investigation and theoretical simulation revealed the dynamic nature of such coordination, which allowed for active manipulation of the optical properties of these molecules by using competing Lewis basic solvents. PMID:27096728

  14. Path planning in multi-scale ocean flows: Coordination and dynamic obstacles

    NASA Astrophysics Data System (ADS)

    Lolla, T.; Haley, P. J., Jr.; Lermusiaux, P. F. J.

    2015-10-01

    As the concurrent use of multiple autonomous vehicles in ocean missions grows, systematic control for their coordinated operation is becoming a necessity. Many ocean vehicles, especially those used in longer-range missions, possess limited operating speeds and are thus sensitive to ocean currents. Yet, the effect of currents on their trajectories is ignored by many coordination techniques. To address this issue, we first derive a rigorous level-set methodology for distance-based coordination of vehicles operating in minimum time within strong and dynamic ocean currents. The new methodology integrates ocean modeling, time-optimal level-sets and optimization schemes to predict the ocean currents, the short-term reachability sets, and the optimal headings for the desired coordination. Schemes are developed for dynamic formation control, where multiple vehicles achieve and maintain a given geometric pattern as they carry out their missions. To do so, a new score function that is suitable for regular polygon formations is obtained. Secondly, we obtain an efficient, non-intrusive technique for level-set-based time-optimal path planning in the presence of moving obstacles. The results are time-optimal path forecasts that rigorously avoid moving obstacles and sustain the desired coordination. They are exemplified and investigated for a variety of simulated ocean flows. A wind-driven double-gyre flow is used to study time-optimal dynamic formation control. Currents exiting an idealized strait or estuary are employed to explore dynamic obstacle avoidance. Finally, results are analyzed for the complex geometry and multi-scale ocean flows of the Philippine Archipelago.

  15. How to measure microtubule dynamics?

    PubMed

    Straube, Anne

    2011-01-01

    Microtubules are one of the most spectacular features in the cell: long, fairly rigid tubules that provide physical strength while at the same time serving as tracks of the intracellular transport network. In addition, they are the main constituents of the cell division machinery, and guide axonal growth and the direction of cell migration. To be able to fulfil such diverse functions, microtubules have to be arranged into suitable patterns and remodelled according to extra- and intracellular cues. Moreover, the delicate regulation of microtubule dynamics and the dynamic interactions with subcellular structures, such as kinetochores or cell adhesion sites, appear to be of crucial importance to microtubule functions. It is, therefore, important to understand microtubule dynamics and its spatiotemporal regulation at the molecular level. In this chapter, I introduce the concept of microtubule dynamics and discuss the techniques that can be employed to study microtubule dynamics in vitro and in cells, for many of which detailed protocols can be found in this volume. Microtubule dynamics is traditionally assessed by the four parameters of dynamic instability: growth and shrinkage rates, rescue and catastrophe frequencies, sometimes supplemented by pause duration. I discuss emerging issues with and alternatives to this parameter description of microtubule dynamics. PMID:21773917

  16. High-precision three-dimensional coordinate measurement with subwavelength-aperture-fiber point diffraction interferometer

    NASA Astrophysics Data System (ADS)

    Wang, Daodang; Xu, Yangbo; Chen, Xixi; Wang, Fumin; Kong, Ming; Zhao, Jun

    2014-11-01

    To overcome the accuracy limitation due to the machining error of standard parts in measurement system, a threedimensional coordinate measurement method with subwavelength-aperture-fiber point diffraction interferometer (PDI) is proposed, in which the high-precision measurement standard is obtained from the ideal point-diffracted spherical wavefront instead of standard components. On the basis of the phase distribution demodulated from point-diffraction interference field, high-precision three-dimensional coordinate measurement is realized with numerical iteration optimization algorithm. The subwavelength-aperture fiber is used as point-diffraction source to get precise and highenergy spherical wavefront within high aperture angle range, by which the conflict between diffraction wave angle and energy in traditional PDI can be avoided. Besides, a double-iterative method based on Levenbery-Marquardt algorithm is proposed to realize precise reconstruct three-dimensional coordinate. The analysis shows that the proposed method can reach the measurement precision better than microns within a 200×200×300 (in unit of mm) working volume. This measurement method does not rely on the initial iteration value in numerical coordinate reconstruction, and also has high measurement precision, large measuring range, fast processing speed and preferable anti-noise ability. It is of great practicality for measurement of three-dimensional coordinate and calibration of measurement system.

  17. Highly dynamic coordination behavior of Pn ligand complexes towards "naked" Cu(+) cations.

    PubMed

    Fleischmann, Martin; Welsch, Stefan; Peresypkina, Eugenia V; Virovets, Alexander V; Scheer, Manfred

    2015-10-01

    Reactions of Cu(+) containing the weakly coordinating anion [Al{OC(CF3 )3 }4 ](-) with the polyphosphorus complexes [{CpMo(CO)2 }2 (μ,η(2) :η(2) -P2 )] (A), [CpM(CO)2 (η(3) -P3 )] (M=Cr(B1), Mo (B2)), and [Cp*Fe(η(5) -P5 )] (C) are presented. The X-ray structures of the products revealed mononuclear (4) and dinuclear (1, 2, 3) Cu(I) complexes, as well as the one-dimensional coordination polymer (5 a) containing an unprecedented [Cu2 (C)3 ](2+) paddle-wheel building block. All products are readily soluble in CH2 Cl2 and exhibit fast dynamic coordination behavior in solution indicated by variable temperature (31) P{(1) H} NMR spectroscopy.

  18. Effect of muscular fatigue on fractal upper limb coordination dynamics and muscle synergies.

    PubMed

    Bueno, Diana R; Lizano, J M; Montano, L

    2015-08-01

    Rehabilitation exercises cause fatigue because tasks are repetitive. Therefore, inevitable human motion performance changes occur during the therapy. Although traditionally fatigue is considered an event that occurs in the musculoskeletal level, this paper studies whether fatigue can be regarded as context that influences lower-dimensional motor control organization and coordination at neural level. Non Negative Factorization Matrix (NNFM) and Detrended Fluctuations Analysis (DFA) are the tools used to analyze the changes in the coordination of motor function when someone is affected by fatigue. The study establishes that synergies remain fairly stable with the onset of fatigue, but the fatigue affects the dynamical coordination understood as a cognitive process. These results have been validated with 9 healthy subjects for three representative exercises for upper limb: biceps, triceps and deltoid. PMID:26737679

  19. Space-time coordination dynamics in basketball: Part 2. The interaction between the two teams.

    PubMed

    Bourbousson, Jérôme; Sève, Carole; McGarry, Tim

    2010-02-01

    In this article, we examine the space-time coordination dynamics of two basketball teams during competition. We identified six game sequences at random, from which the movement data of each player were obtained for analysis of team behaviours in both the longitudinal (basket-to-basket) and lateral (side-to-side) directions. The central position of a team was measured using its spatial (geometric) centre and dispersion using a stretch index, obtained from the mean distance of team members from the spatial centre. Relative-phase analysis of the spatial centres demonstrated in-phase stabilities in both the longitudinal and lateral directions, with more stability in the longitudinal than lateral direction. As anticipated, this finding is consistent with the results of an analysis of individual playing dyads (see companion article, this issue), as well as the more general principle of complex systems conforming to similar descriptions at different levels of analysis. Phase relations for the stretch index demonstrated in-phase attraction in the longitudinal direction and no attraction to any values in the lateral direction. Finally, the difference between the two stretch indexes at any instant showed phase transitions between two stable patterns when the difference was represented in binary form. This result is attributed to the reciprocity between teams in their amounts of expansion and contraction when possession of the ball is won and lost.

  20. Differing Dynamics of Intrapersonal and Interpersonal Coordination: Two-finger and Four-Finger Tapping Experiments

    PubMed Central

    Kodama, Kentaro; Furuyama, Nobuhiro; Inamura, Tetsunari

    2015-01-01

    Finger-tapping experiments were conducted to examine whether the dynamics of intrapersonal and interpersonal coordination systems can be described equally by the Haken—Kelso—Bunz model, which describes inter-limb coordination dynamics. This article reports the results of finger-tapping experiments conducted in both systems. Two within-subject factors were investigated: the phase mode and the number of fingers. In the intrapersonal experiment (Experiment 1), the participants were asked to tap, paced by a gradually hastening auditory metronome, looking at their fingers moving, using the index finger in the two finger condition, or the index and middle finger in the four-finger condition. In the interpersonal experiment (Experiment 2), pairs of participants performed the task while each participant used the outside hand, tapping with the index finger in the two finger condition, or the index and middle finger in the four-finger condition. Some results did not agree with the HKB model predictions. First, from Experiment 1, no significant difference was observed in the movement stability between the in-phase and anti-phase modes in the two finger condition. Second, from Experiment 2, no significant difference was found in the movement stability between the in-phase and anti-phase mode in the four-finger condition. From these findings, different coordination dynamics were inferred between intrapersonal and interpersonal coordination systems against prediction from the previous studies. Results were discussed according to differences between intrapersonal and interpersonal coordination systems in the availability of perceptual information and the complexity in the interaction between limbs derived from a nested structure. PMID:26070119

  1. Dynamic modeling and optimal joint torque coordination of advanced robotic systems

    NASA Astrophysics Data System (ADS)

    Kang, Hee-Jun

    The development is documented of an efficient dynamic modeling algorithm and the subsequent optimal joint input load coordination of advanced robotic systems for industrial application. A closed-form dynamic modeling algorithm for the general closed-chain robotic linkage systems is presented. The algorithm is based on the transfer of system dependence from a set of open chain Lagrangian coordinates to any desired system generalized coordinate set of the closed-chain. Three different techniques for evaluation of the kinematic closed chain constraints allow the representation of the dynamic modeling parameters in terms of system generalized coordinates and have no restriction with regard to kinematic redundancy. The total computational requirement of the closed-chain system model is largely dependent on the computation required for the dynamic model of an open kinematic chain. In order to improve computational efficiency, modification of an existing open-chain KIC based dynamic formulation is made by the introduction of the generalized augmented body concept. This algorithm allows a 44 pct. computational saving over the current optimized one (O(N4), 5995 when N = 6). As means of resolving redundancies in advanced robotic systems, local joint torque optimization is applied for effectively using actuator power while avoiding joint torque limits. The stability problem in local joint torque optimization schemes is eliminated by using fictitious dissipating forces which act in the necessary null space. The performance index representing the global torque norm is shown to be satisfactory. In addition, the resulting joint motion trajectory becomes conservative, after a transient stage, for repetitive cyclic end-effector trajectories. The effectiveness of the null space damping method is shown. The modular robot, which is built of well defined structural modules from a finite-size inventory and is controlled by one general computer system, is another class of evolving

  2. Switching among graphic patterns is governed by oscillatory coordination dynamics: implications for understanding handwriting

    PubMed Central

    Zanone, Pier-Giorgio; Athènes, Sylvie

    2013-01-01

    Revisiting an original idea by Hollerbach (1981), previous work has established that the production of graphic shapes, assumed to be the blueprint for handwriting, is governed by the dynamics of orthogonal non-linear coupled oscillators. Such dynamics determines few stable coordination patterns, giving rise to a limited set of preferred graphic shapes, namely, four lines and four ellipsoids independent of orientation. The present study investigates the rules of switching among such graphic coordination patterns. Seven participants were required to voluntarily switch within twelve pairs of shapes presented on a graphic tablet. In line with previous theoretical and experimental work on bimanual coordination, results corroborated our hypothesis that the relative stability of the produced coordination patterns determines the time needed for switching: the transition to a more stable pattern was shorter, and inversely. Moreover, switching between patterns with the same orientation but different eccentricities was faster than with a change in orientation. Nonetheless, the switching time covaried strictly with the change in relative phase effected by the transition between two shapes, whether this implied a change in eccentricity or in orientation. These findings suggest a new operational definition of what the (motor) units or strokes of handwriting are and shed a novel light on how coarticulation and recruitment of degrees of freedom may occur in graphic skills. They also yield some leads for understanding the acquisition and the neural underpinnings of handwriting. PMID:24069014

  3. Investigation of the complex reaction coordinate of acid catalyzed amide hydrolysis from molecular dynamics simulations

    NASA Astrophysics Data System (ADS)

    Zahn, Dirk

    2004-05-01

    The rate-determining step of acid catalyzed peptide hydrolysis is the nucleophilic attack of a water molecule to the carbon atom of the amide group. Therein the addition of the hydroxyl group to the amide carbon atom involves the association of a water molecule transferring one of its protons to an adjacent water molecule. The protonation of the amide nitrogen atom follows as a separate reaction step. Since the nucleophilic attack involves the breaking and formation of several bonds, the underlying reaction coordinate is rather complex. We investigate this reaction step from path sampling Car-Parrinello molecular dynamics simulations. This approach does not require the predefinition of reaction coordinates and is thus particularly suited for investigating reaction mechanisms. From our simulations the most relevant components of the reaction coordinate are elaborated. Though the C⋯O distance of the oxygen atom of the water molecule performing the nucleophilic attack and the corresponding amide carbon atom is a descriptor of the reaction progress, a complete picture of the reaction coordinate must include all three molecules taking part in the reaction. Moreover, the proton transfer is found to depend on favorable solvent configurations. Thus, also the arrangement of non-reacting, i.e. solvent water molecules needs to be considered in the reaction coordinate.

  4. Insight into the molecular dynamics of guest cations confined in deformable azido coordination frameworks.

    PubMed

    Du, Zi-Yi; Sun, Yu-Zhi; Chen, Shao-Li; Huang, Bo; Su, Yu-Jun; Xu, Ting-Ting; Zhang, Wei-Xiong; Chen, Xiao-Ming

    2015-11-01

    The molecular dynamics of encapsulated cations within perovskite-like coordination polymers [(CH3)3NH][M(N3)3] (M = Mn, Cd) are investigated, which are well controlled by the confined space of a deformable azido framework. The Mn-based compound provides a rare example that features an unvaried/varied rotational energy barrier during its two different structural phase transitions.

  5. Insight into the molecular dynamics of guest cations confined in deformable azido coordination frameworks.

    PubMed

    Du, Zi-Yi; Sun, Yu-Zhi; Chen, Shao-Li; Huang, Bo; Su, Yu-Jun; Xu, Ting-Ting; Zhang, Wei-Xiong; Chen, Xiao-Ming

    2015-11-01

    The molecular dynamics of encapsulated cations within perovskite-like coordination polymers [(CH3)3NH][M(N3)3] (M = Mn, Cd) are investigated, which are well controlled by the confined space of a deformable azido framework. The Mn-based compound provides a rare example that features an unvaried/varied rotational energy barrier during its two different structural phase transitions. PMID:26365090

  6. Coordinated airborne and satellite measurements of equatorial plasma depletions

    SciTech Connect

    Weber, E.J.; Brinton, H.C.; Buchau, J.; Moore, J.G.

    1982-12-01

    A series of experiments was conducted in December 1979 to investigate the structure of plasma depletions in the low latitude, nightime ionosphere. The measurements included all sky imaging photometer (ASIP), ionosonde and amplitude scintillation observations from the AFGL Airborne Ionospheric Observatory (AIO), and in situ ion density measurements from the Atmosphere Explorer (AE-E) Bennett Ion Mass Spectrometer (BIMS). The AIO performed two flights along the Ascension Island (-18/sup 0/ MLAT) magnetic meridian: one in the southern hemisphere and one near the Ascension conjugate point in the northern hemisphere. During these flights, measurements from the AE-E satellite at 434 km altitude are compared with simultaneous remote ionospheric measurements from the AIO. Density biteouts of approximately one order of magnitude in the dominant ion O/sup +/, were mapped to lower altitudes along magnetic field lines for comparison with 6300-A and 7774-A O I airglow depletions. Because of the different airglow production mechanisms (dissociative recombination of O/sup +//sub 2/ for 6300 A and radiative recombination of O/sup +/ for 7774 A) the 6300-A depletions reflect plasma depletions near the bottomside of the F layer, while those at 7774 A are located near the peak of the layer. The O/sup +/ biteouts map directly into the 7774-A airglow depletions in the same hemisphere and also when traced into the opposite hemisphere, which indicates magnetic flux tube alignment over north-south distances of approx.2220 km. The 6300-A (bottomside) depletions are wider in longitude than the 7774-A (F-peak) depletions near the equatorward edge of the Appleton anomaly. This difference in topside and bottomside structure is used to infer large-scale structure near the anomaly and to relate this to structure, commonly observed near the magnetic equator by the ALTAIR radar.

  7. Sensor Prototype to Evaluate the Contact Force in Measuring with Coordinate Measuring Arms

    PubMed Central

    Cuesta, Eduardo; Telenti, Alejandro; Patiño, Hector; González-Madruga, Daniel; Martínez-Pellitero, Susana

    2015-01-01

    This paper describes the design, development and evaluation tests of an integrated force sensor prototype for portable Coordinate Measuring Arms (CMAs or AACMMs). The development is based on the use of strain gauges located on the surface of the CMAs’ hard probe. The strain gauges as well as their cables and connectors have been protected with a custom case, made by Additive Manufacturing techniques (Polyjet 3D). The same method has been selected to manufacture an ergonomic handle that includes trigger mechanics and the electronic components required for synchronizing the trigger signal when probing occurs. The paper also describes the monitoring software that reads the signals in real time, the calibration procedure of the prototype and the validation tests oriented towards increasing knowledge of the forces employed in manual probing. Several experiments read and record the force in real time comparing different ways of probing (discontinuous and continuous contact) and measuring different types of geometric features, from single planes to exterior cylinders, cones, or spheres, through interior features. The probing force is separated into two components allowing the influence of these strategies in probe deformation to be known. The final goal of this research is to improve the probing technique, for example by using an operator training programme, allowing extra-force peaks and bad contacts to be minimized or just to avoid bad measurements. PMID:26057038

  8. Sensor Prototype to Evaluate the Contact Force in Measuring with Coordinate Measuring Arms.

    PubMed

    Cuesta, Eduardo; Telenti, Alejandro; Patiño, Hector; González-Madruga, Daniel; Martínez-Pellitero, Susana

    2015-01-01

    This paper describes the design, development and evaluation tests of an integrated force sensor prototype for portable Coordinate Measuring Arms (CMAs or AACMMs). The development is based on the use of strain gauges located on the surface of the CMAs' hard probe. The strain gauges as well as their cables and connectors have been protected with a custom case, made by Additive Manufacturing techniques (Polyjet 3D). The same method has been selected to manufacture an ergonomic handle that includes trigger mechanics and the electronic components required for synchronizing the trigger signal when probing occurs. The paper also describes the monitoring software that reads the signals in real time, the calibration procedure of the prototype and the validation tests oriented towards increasing knowledge of the forces employed in manual probing. Several experiments read and record the force in real time comparing different ways of probing (discontinuous and continuous contact) and measuring different types of geometric features, from single planes to exterior cylinders, cones, or spheres, through interior features. The probing force is separated into two components allowing the influence of these strategies in probe deformation to be known. The final goal of this research is to improve the probing technique, for example by using an operator training programme, allowing extra-force peaks and bad contacts to be minimized or just to avoid bad measurements. PMID:26057038

  9. Sensor Prototype to Evaluate the Contact Force in Measuring with Coordinate Measuring Arms.

    PubMed

    Cuesta, Eduardo; Telenti, Alejandro; Patiño, Hector; González-Madruga, Daniel; Martínez-Pellitero, Susana

    2015-06-05

    This paper describes the design, development and evaluation tests of an integrated force sensor prototype for portable Coordinate Measuring Arms (CMAs or AACMMs). The development is based on the use of strain gauges located on the surface of the CMAs' hard probe. The strain gauges as well as their cables and connectors have been protected with a custom case, made by Additive Manufacturing techniques (Polyjet 3D). The same method has been selected to manufacture an ergonomic handle that includes trigger mechanics and the electronic components required for synchronizing the trigger signal when probing occurs. The paper also describes the monitoring software that reads the signals in real time, the calibration procedure of the prototype and the validation tests oriented towards increasing knowledge of the forces employed in manual probing. Several experiments read and record the force in real time comparing different ways of probing (discontinuous and continuous contact) and measuring different types of geometric features, from single planes to exterior cylinders, cones, or spheres, through interior features. The probing force is separated into two components allowing the influence of these strategies in probe deformation to be known. The final goal of this research is to improve the probing technique, for example by using an operator training programme, allowing extra-force peaks and bad contacts to be minimized or just to avoid bad measurements.

  10. Interplay of structure and vibrational dynamics in six-coordinate heme nitrosyls.

    SciTech Connect

    Silvernail, N. J.; Barabanschikov, A.; Pavlik, J. W.; Noll, B. C.; Zhao, J.; Alp, E. E.; Sturhahn, W.; Stage, J. T.; Scheidt, W. R.; Univ. of Notre Dame; Notheastern Univ.

    2007-02-02

    The isolation of two polymorphic forms of nitrosyl(1-methylimidazole)(tetra-p-fluorophenylporphinato)iron(II) provides a unique opportunity to explore the interplay of structure and vibrational dynamics in six-coordinate {l_brace}FeNO{r_brace}{sup 7} nitrosyliron porphyrinates. The two species display differing vibrational spectroscopic properties both in {nu}{sub NO} (IR) and the iron vibrational modes obtained through the use of nuclear resonance vibrational spectroscopy. Structural characterization of the two complexes has yielded extremely high-quality structures that further confirm that coordination of NO leads to ligand tilting and asymmetry in the equatorial Fe-Np bond distances. The two polymorphic structures (monoclinic and triclinic crystal systems) differ in the relative orientations of the two axial ligands and small but significant differences in coordination group bond distances. Although DFT calculations suggest that the NO/imidazole orientations should be indistinguishable, real experimental (structural and vibrational) differences between the two are found. The observed variation in the axial and equatorial Fe-N bonds is strongly correlated to the dynamics of the Fe-NO unit and other motions of iron. Other structural differences appear to have little effect on the vibrational properties of the two forms. The in-plane motions of iron in CO versus NO heme complexes illustrate distinct dynamic differences.

  11. Comparison of clinical bracket point registration with 3D laser scanner and coordinate measuring machine

    PubMed Central

    Nouri, Mahtab; Farzan, Arash; Baghban, Ali Reza Akbarzadeh; Massudi, Reza

    2015-01-01

    OBJECTIVE: The aim of the present study was to assess the diagnostic value of a laser scanner developed to determine the coordinates of clinical bracket points and to compare with the results of a coordinate measuring machine (CMM). METHODS: This diagnostic experimental study was conducted on maxillary and mandibular orthodontic study casts of 18 adults with normal Class I occlusion. First, the coordinates of the bracket points were measured on all casts by a CMM. Then, the three-dimensional coordinates (X, Y, Z) of the bracket points were measured on the same casts by a 3D laser scanner designed at Shahid Beheshti University, Tehran, Iran. The validity and reliability of each system were assessed by means of intraclass correlation coefficient (ICC) and Dahlberg's formula. RESULTS: The difference between the mean dimension and the actual value for the CMM was 0.0066 mm. (95% CI: 69.98340, 69.99140). The mean difference for the laser scanner was 0.107 ± 0.133 mm (95% CI: -0.002, 0.24). In each method, differences were not significant. The ICC comparing the two methods was 0.998 for the X coordinate, and 0.996 for the Y coordinate; the mean difference for coordinates recorded in the entire arch and for each tooth was 0.616 mm. CONCLUSION: The accuracy of clinical bracket point coordinates measured by the laser scanner was equal to that of CMM. The mean difference in measurements was within the range of operator errors. PMID:25741826

  12. Coordination number of zinc ions in the phosphotriesterase active site by molecular dynamics and quantum mechanics.

    PubMed

    Koca, Jaroslav; Zhan, Chang-Guo; Rittenhouse, Robert C; Ornstein, Rick L

    2003-02-01

    We have run several molecular dynamics (MD) simulations on zinc-containing phosphotriesterase (PTE) with two bound substrates, sarin and paraoxon, and with the substrate analog diethyl 4-methylbenzylphosphonate. A standard nonbonded model was employed to treat the zinc ions with the commonly used charge of +2. In all the trajectories, we observed a tightly bound water (TBW) molecule in the active site that was coordinated to the less buried zinc ion. The phosphoryl oxygen of the substrate/inhibitor was found to be coordinated to the same zinc ion so that, considering all ligands, the less buried zinc was hexa-coordinated. The hexa-coordination of this zinc ion was not seen in the deposited X-ray pdb files for PTE. Several additional MD simulations were then performed using different charges (+1, +1.5) on the zinc ions, along with ab initio and density functional theory (DFT) calculations, to evaluate the following possibilities: the crystal diffraction data were not correctly interpreted; the hexa-coordinated zinc ion in PTE is only present in solution and not in the crystal; and the hexa-coordinated zinc ion in PTE is an artifact of the force field used. A charge of +1.5 leads to a coordination number (CN) of 5 on both zinc ions, which is consistent with the results from ab initio and DFT calculations and with the latest high resolution X-ray crystal structure. The commonly used charge of +2 produces a CN of 6 on the less buried zinc. The CN on the more buried zinc ion is 5 when the substrate/inhibitor is present in the simulation, and increases to 6 when the substrate/inhibitor is removed prior to the simulation. The results of both of the MD and quantum mechanical calculations lead to the conclusion that the zinc ions in the PTE active site are both penta-coordinated, and that the MD simulations performed with the charge of +2 overestimate the CN of the zinc ions in the PTE active site. The overall protein structures in the simulations remain unaffected by the

  13. Students' Coordination of Geometric Reasoning and Measuring Strategies on a Fixed Perimeter Task: Developing Mathematical Understanding of Linear Measurement

    ERIC Educational Resources Information Center

    Barrett, Jeffrey E.; Clements, Douglas H.; Klanderman, David; Pennisi, Sarah-Jean; Polaki, Mokaeane V.

    2006-01-01

    This article examines students' development of levels of understanding for measurement by describing the coordination of geometric reasoning with measurement and numerical strategies. In analyzing the reasoning and argumentation of 38 Grade 2 through Grade 10 students on linear measure tasks, we found support for the application and elaboration of…

  14. Coordination of Flow and Traction in Migration of Amoeboid Physarum polycephalum: Model and Measurement

    NASA Astrophysics Data System (ADS)

    Lewis, Owen; Guy, Robert; Zhang, Shun; Del Alamo, Juan Carlos

    2014-11-01

    In this research, we develop a computational model of crawling Physarum based on the Immersed Boundary Method. Our model incorporates the effects of cell cytoplasm, the internal cytoskeleton and adhesions to the substrate. Cytoplasmic flows and traction stresses predicted by the model are compared to experimentally measured values obtained using simultaneous Traction Force Microscopy (TFM) and Particle Image Velocimetry (PIV). Of particular interest are stresses generated by flow and how transmission of stresses to the substrate is coordinated. We identify methods of adhesion-flow coordination which are consistent with experiments. Certain consisten coordinations are seen to be ``optimal'' with regards to crawling speed, and robust to perturbations in the extracellular environment.

  15. Setting standards at the forefront of delivery system reform: aligning care coordination quality measures for multiple chronic conditions.

    PubMed

    DuGoff, Eva H; Dy, Sydney; Giovannetti, Erin R; Leff, Bruce; Boyd, Cynthia M

    2013-01-01

    The primary study objective is to assess how three major health reform care coordination initiatives (Accountable Care Organizations, Independence at Home, and Community-Based Care Transitions) measure concepts critical to care coordination for people with multiple chronic conditions. We find that there are major differences in quality measurement across these three large and politically important programs. Quality measures currently used or proposed for these new health reform-related programs addressing care coordination primarily capture continuity of care. Other key areas of care coordination, such as care transitions, patient-centeredness, and cross-cutting care across multiple conditions are infrequently addressed. The lack of a comprehensive and consistent measure set for care coordination will pose challenges for healthcare providers and policy makers who seek, respectively, to provide and reward well-coordinated care. In addition, this heterogeneity in measuring care coordination quality will generate new information, but will inhibit comparisons between these care coordination programs.

  16. A practical coordinate unification method for integrated tactile-optical measuring system

    NASA Astrophysics Data System (ADS)

    Li, Feng; Peter Longstaff, Andrew; Fletcher, Simon; Myers, Alan

    2014-04-01

    To meet the requirement of both high speed and high accuracy 3D measurements for dimensional metrology, multi-sensor measuring systems have been developed to measure, analyse and reverse engineer the geometry of objects. This paper presents a new development in coordinate unification called the "centroid of spherical centres" method, which can be used instead of the traditional method which uses three datum-points to perform the geometric transformation and unification of tactile and optical sensors. The benefits of the proposed method are improved accuracy in coordinate unification and the method is used to integrate a coordinate measuring machine (CMM) and optical sensors (structured light scanning system and FaroArm laser line probe). A sphere-plate artefact is developed for data fusion of the multi-sensor system and experimental results validate the accuracy and effectiveness of this method.

  17. Research on performance evaluation of non-arm coordinate measuring machine (NACMM)

    NASA Astrophysics Data System (ADS)

    Wang, Weinong; Wei, Hengzheng; Xia, Yang

    2010-11-01

    The methods for performance evaluation of Articulated Arm Coordinate Measuring Machine (AACMM) have been published. Non-arm Coordinate Measuring Machine (NACMM) is similar with AACMM in function, and then the performance evaluation methods should be also similar. The research based on comparing the principle and error resources of the both systems, set up a new combination of the position, orientation and test number, try to locate a more reasonable procedure in evaluate the performance of NACMMs which can be comparable with ASME B89.4.22-2004, but better for find the characteristic of accuracy changing in measurement volume. The procedure is confirmed by testing of different NACMMs.

  18. Contact dynamics of elasto-plastic thin beams simulated via absolute nodal coordinate formulation

    NASA Astrophysics Data System (ADS)

    Wang, Qing-Tao; Tian, Qiang; Hu, Hai-Yan

    2016-06-01

    Under the frame of multibody dynamics, the contact dynamics of elasto-plastic spatial thin beams is numerically studied by using the spatial thin beam elements of absolute nodal coordinate formulation (ANCF). The internal force of the elasto-plastic spatial thin beam element is derived under the assumption that the plastic strain of the beam element depends only on its longitudinal deformation. A new body-fixed local coordinate system is introduced into the spatial thin beam element of ANCF for efficient contact detection in the contact dynamics simulation. The linear isotropic hardening constitutive law is used to describe the elasto-plastic deformation of beam material, and the classical return mapping algorithm is adopted to evaluate the plastic strains. A multi-zone contact approach of thin beams previously proposed by the authors is also introduced to detect the multiple contact zones of beams accurately, and the penalty method is used to compute the normal contact force of thin beams in contact. Four numerical examples are given to demonstrate the applicability and effectiveness of the proposed elasto-plastic spatial thin beam element of ANCF for flexible multibody system dynamics.

  19. Design and verification of an ultra-precision 3D-coordinate measuring machine with parallel drives

    NASA Astrophysics Data System (ADS)

    Bos, Edwin; Moers, Ton; van Riel, Martijn

    2015-08-01

    An ultra-precision 3D coordinate measuring machine (CMM), the TriNano N100, has been developed. In our design, the workpiece is mounted on a 3D stage, which is driven by three parallel drives that are mutually orthogonal. The linear drives support the 3D stage using vacuum preloaded (VPL) air bearings, whereby each drive determines the position of the 3D stage along one translation direction only. An exactly constrained design results in highly repeatable machine behavior. Furthermore, the machine complies with the Abbé principle over its full measurement range and the application of parallel drives allows for excellent dynamic behavior. The design allows a 3D measurement uncertainty of 100 nanometers in a measurement range of 200 cubic centimeters. Verification measurements using a Gannen XP 3D tactile probing system on a spherical artifact show a standard deviation in single point repeatability of around 2 nm in each direction.

  20. Coordination, Organisation and Model-driven Approaches for Dynamic, Flexible, Robust Software and Services Engineering

    NASA Astrophysics Data System (ADS)

    Nieves, Juan Carlos; Padget, Julian; Vasconcelos, Wamberto; Staikopoulos, Athanasios; Cliffe, Owen; Dignum, Frank; Vázquez-Salceda, Javier; Clarke, Siobhán; Reed, Chris

    Enterprise systems are increasingly composed of (and even functioning as) components in a dynamic, digital ecosystem. On the one hand, this new situation requires flexible, spontaneous and opportunistic collaboration activities to be identified and established among (electronic) business parties. On the other, it demands engineering methods that are able to integrate new functionalities and behaviours into running systems composed by active, distributed, interdependent processes. Here we present a multi-level architecture that combines organisational and coordination theories with model driven development, for the implementation, deployment and management of dynamic, flexible and robust service-oriented business applications, combined with a service layer that accommodates semantic service description, fine-grained semantic service discovery and the dynamic adaptation of services to meet changing circumstances.

  1. Dynamic measurements of beam-pump parameters

    SciTech Connect

    Lea, J.F.; Bowen, J.F. )

    1992-02-01

    Measurements of nine electrical and mechanical parameters were made on conventional and special-geometry units during operation of beam-pump/sucker rod systems in oil and natural gas wells. All quantities were measured simultaneously and computer-recorded for a variety of pumping conditions. In this paper, using this data, the authors compared measured dynamic gearbox torques with calculated values, illustrating how calculation techniques model dynamically measured data. Calculated efficiencies indicating losses through the units from polished rod to the gearbox are shown to be necessary for adjusting gearbox torque calculations to measured values. Also, torque/speed curves are shown at the motor sheave. These data are corrected for inertial effects and plotted vs. motor manufacturers' published curves. Possibilities for future work incorporating these measurement techniques while the unit is in operation were discussed. In general, the data show how dynamically measured beam-pump data compare with conventional calculation techniques.

  2. Dynamic temperature measurements with embedded optical sensors.

    SciTech Connect

    Dolan, Daniel H.,; Seagle, Christopher T; Ao, Tommy

    2013-10-01

    This report summarizes LDRD project number 151365, \\Dynamic Temperature Measurements with Embedded Optical Sensors". The purpose of this project was to develop an optical sensor capable of detecting modest temperature states (<1000 K) with nanosecond time resolution, a recurring diagnostic need in dynamic compression experiments at the Sandia Z machine. Gold sensors were selected because the visible re ectance spectrum of gold varies strongly with temperature. A variety of static and dynamic measurements were performed to assess re ectance changes at di erent temperatures and pressures. Using a minimal optical model for gold, a plausible connection between static calibrations and dynamic measurements was found. With re nements to the model and diagnostic upgrades, embedded gold sensors seem capable of detecting minor (<50 K) temperature changes under dynamic compression.

  3. Molecular dynamic simulations of the lithium coordination environment in phosphate glasses

    SciTech Connect

    ALAM,TODD M.; LIANG,JIANJIE; CYGAN,RANDALL T.

    2000-06-07

    A molecular dynamics (MD) study of the lithium ultraphosphate glass series, xLi{sub 2}O{center_dot}(1{minus}x)P{sub 2}O{sub 5} (0 {le} x < 0.5) was used to investigate the changes in the Li environment with increasing modifier concentration. The results from the MD simulations indicate that no major structural variations in the Li coordination environment are observed. Changes in the type of oxygen coordinated to the modifier are observed and correlate with the T{sub g} minimum. Additionally, changes in the number of shared phosphorus vertices are observed with increasing modifier concentration, in support of recent models involving the role of the modifier in the extended range structure of phosphate glasses. Empirical calculations of the {sup 6}Li NMR chemical shifts directly from the MD simulation structures is also reported and compared to recent experimental solid-state NMR results.

  4. Traffic Management Coordinator Evaluation of the Dynamic Weather Routes Concept and System

    NASA Technical Reports Server (NTRS)

    Gong, Chester

    2014-01-01

    Dynamic Weather Routes (DWR) is a weather-avoidance system for airline dispatchers and FAA traffic managers that continually searches for and advises the user of more efficient routes around convective weather. NASA and American Airlines (AA) have been conducting an operational trial of DWR since July 17, 2012. The objective of this evaluation is to assess DWR from a traffic management coordinator (TMC) perspective, using recently retired TMCs and actual DWR reroutes advisories that were rated acceptable by AA during the operational trial. Results from the evaluation showed that the primary reasons for a TMC to modify or reject airline reroute requests were related to airspace configuration. Approximately 80 percent of the reroutes evaluated required some coordination before implementation. Analysis showed TMCs approved 62 percent of the requested DWR reroutes, resulting in 57 percent of the total requested DWR time savings.

  5. Hamilton-Jacobi tunneling method for dynamical horizons in different coordinate gauges

    NASA Astrophysics Data System (ADS)

    Di Criscienzo, Roberto; Hayward, Sean A.; Nadalini, Mario; Vanzo, Luciano; Zerbini, Sergio

    2010-01-01

    Previous work on dynamical black hole instability is further elucidated within the Hamilton-Jacobi method for horizon tunneling and the reconstruction of the classical action by means of the null expansion method. Everything is based on two natural requirements, namely that the tunneling rate is an observable and therefore it must be based on invariantly defined quantities, and that coordinate systems which do not cover the horizon should not be admitted. These simple observations can help to clarify some ambiguities, like the doubling of the temperature occurring in the static case when using singular coordinates and the role, if any, of the temporal contribution of the action to the emission rate. The formalism is also applied to FRW cosmological models, where it is observed that it predicts the positivity of the temperature naturally, without further assumptions on the sign of energy.

  6. Measurements of glottal structure dynamics

    NASA Astrophysics Data System (ADS)

    Holzrichter, John F.; Ng, Lawrence C.; Burke, Gerry J.; Champagne, Nathan J.; Kallman, Jeffrey S.; Sharpe, Robert M.; Kobler, James B.; Hillman, Robert E.; Rosowski, John J.

    2005-03-01

    Low power, radarlike electromagnetic (EM) wave sensors, operating in a homodyne interferometric mode, are being used to measure tissue motions in the human vocal tract during speech. However, when these and similar sensors are used in front of the laryngeal region during voiced speech, there remains an uncertainty regarding the contributions to the sensor signal from vocal fold movements versus those from pressure induced trachea-wall movements. Several signal-source hypotheses are tested by performing experiments with a subject who had undergone tracheostomy, and who still was able to phonate when her stoma was covered (e.g., with a plastic plate). Laser-doppler motion-measurements of the subject's posterior trachea show small tissue movements, about 15 microns, that do not contribute significantly to signals from presently used EM sensors. However, signals from the anterior wall do contribute. EM sensor and air-pressure measurements, together with 3-D EM wave simulations, show that EM sensors measure movements of the vocal folds very well. The simulations show a surprisingly effective guiding of EM waves across the vocal fold membrane, which, upon glottal opening, are interrupted and reflected. These measurements are important for EM sensor applications to speech signal de-noising, vocoding, speech recognition, and diagnostics. .

  7. Dynamic contact angle measurements on superhydrophobic surfaces

    NASA Astrophysics Data System (ADS)

    Kim, Jeong-Hyun; Kavehpour, H. Pirouz; Rothstein, Jonathan P.

    2015-03-01

    In this paper, the dynamic advancing and receding contact angles of a series of aqueous solutions were measured on a number of hydrophobic and superhydrophobic surfaces using a modified Wilhelmy plate technique. Superhydrophobic surfaces are hydrophobic surfaces with micron or nanometer sized surface roughness. These surfaces have very large static advancing contact angles and little static contact angle hysteresis. In this study, the dynamic advancing and dynamic receding contact angles on superhydrophobic surfaces were measured as a function of plate velocity and capillary number. The dynamic contact angles measured on a smooth hydrophobic Teflon surface were found to obey the scaling with capillary number predicted by the Cox-Voinov-Tanner law, θD3 ∝ Ca. The response of the dynamic contact angle on the superhydrophobic surfaces, however, did not follow the same scaling law. The advancing contact angle was found to remain constant at θA = 160∘, independent of capillary number. The dynamic receding contact angle measurements on superhydrophobic surfaces were found to decrease with increasing capillary number; however, the presence of slip on the superhydrophobic surface was found to result in a shift in the onset of dynamic contact angle variation to larger capillary numbers. In addition, a much weaker dependence of the dynamic contact angle on capillary number was observed for some of the superhydrophobic surfaces tested.

  8. Dynamic Force Measurement with Strain Gauges

    ERIC Educational Resources Information Center

    Lee, Bruce E.

    1974-01-01

    Discusses the use of four strain gauges, a Wheatstone bridge, and an oscilloscope to measure forces dynamically. Included is an example of determining the centripetal force of a pendulum in a general physics laboratory. (CC)

  9. Large Dynamic Range Beam Profile Measurements

    SciTech Connect

    A. P. Freyberger

    2005-06-01

    Large dynamic range (Peak/Noise >10{sup 5}) beam profile measurements are routinely performed in the Hall-B beamline at Jefferson Lab. These measurements are made with a 1 to 10nA electron beam current with energies between 1 to 6 GeV. The electron beam scatters off of a thin W or Fe wire and the scattered particle/shower is detected via scintillation or Cerenkov light several meters downstream of the wire. This report describes results on increasing the dynamic range by using multiple wires of varying diameters. Profile measurements with this large dynamic range are of use for accelerators with very stored energy (e.g. energy recovering linacs [ERL]) where small beam loss represents a significant amount of beam power. Results on measuring the transverse profile with large dynamic range during the CEBAF energy recovery experiment is also presented.

  10. Minimization of deviations of gear real tooth surfaces determined by coordinate measurements

    NASA Technical Reports Server (NTRS)

    Litvin, F. L.; Kuan, C.; Wang, J.-C.; Handschuh, R. F.; Masseth, J.; Maruyama, N.

    1992-01-01

    The deviations of a gear's real tooth surface from the theoretical surface are determined by coordinate measurements at the grid of the surface. A method was developed to transform the deviations from Cartesian coordinates to those along the normal at the measurement locations. Equations are derived that relate the first order deviations with the adjustment to the manufacturing machine-tool settings. The deviations of the entire surface are minimized. The minimization is achieved by application of the least-square method for an overdetermined system of linear equations. The proposed method is illustrated with a numerical example for hypoid gear and pinion.

  11. Impact loading and locomotor-respiratory coordination significantly influence breathing dynamics in running humans.

    PubMed

    Daley, Monica A; Bramble, Dennis M; Carrier, David R

    2013-01-01

    Locomotor-respiratory coupling (LRC), phase-locking between breathing and stepping rhythms, occurs in many vertebrates. When quadrupedal mammals gallop, 1∶1 stride per breath coupling is necessitated by pronounced mechanical interactions between locomotion and ventilation. Humans show more flexibility in breathing patterns during locomotion, using LRC ratios of 2∶1, 2.5∶1, 3∶1, or 4∶1 and sometimes no coupling. Previous studies provide conflicting evidence on the mechanical significance of LRC in running humans. Some studies suggest LRC improves breathing efficiency, but others suggest LRC is mechanically insignificant because 'step-driven flows' (ventilatory flows attributable to step-induced forces) contribute a negligible fraction of tidal volume. Yet, although step-driven flows are brief, they cause large fluctuations in ventilatory flow. Here we test the hypothesis that running humans use LRC to minimize antagonistic effects of step-driven flows on breathing. We measured locomotor-ventilatory dynamics in 14 subjects running at a self-selected speed (2.6±0.1 ms(-1)) and compared breathing dynamics in their naturally 'preferred' and 'avoided' entrainment patterns. Step-driven flows occurred at 1-2X step frequency with peak magnitudes of 0.97±0.45 Ls(-1) (mean ±S.D). Step-driven flows varied depending on ventilatory state (high versus low lung volume), suggesting state-dependent changes in compliance and damping of thoraco-abdominal tissues. Subjects naturally preferred LRC patterns that minimized antagonistic interactions and aligned ventilatory transitions with assistive phases of the step. Ventilatory transitions initiated in 'preferred' phases within the step cycle occurred 2x faster than those in 'avoided' phases. We hypothesize that humans coordinate breathing and locomotion to minimize antagonistic loading of respiratory muscles, reduce work of breathing and minimize rate of fatigue. Future work could address the potential consequences of

  12. Impact loading and locomotor-respiratory coordination significantly influence breathing dynamics in running humans.

    PubMed

    Daley, Monica A; Bramble, Dennis M; Carrier, David R

    2013-01-01

    Locomotor-respiratory coupling (LRC), phase-locking between breathing and stepping rhythms, occurs in many vertebrates. When quadrupedal mammals gallop, 1∶1 stride per breath coupling is necessitated by pronounced mechanical interactions between locomotion and ventilation. Humans show more flexibility in breathing patterns during locomotion, using LRC ratios of 2∶1, 2.5∶1, 3∶1, or 4∶1 and sometimes no coupling. Previous studies provide conflicting evidence on the mechanical significance of LRC in running humans. Some studies suggest LRC improves breathing efficiency, but others suggest LRC is mechanically insignificant because 'step-driven flows' (ventilatory flows attributable to step-induced forces) contribute a negligible fraction of tidal volume. Yet, although step-driven flows are brief, they cause large fluctuations in ventilatory flow. Here we test the hypothesis that running humans use LRC to minimize antagonistic effects of step-driven flows on breathing. We measured locomotor-ventilatory dynamics in 14 subjects running at a self-selected speed (2.6±0.1 ms(-1)) and compared breathing dynamics in their naturally 'preferred' and 'avoided' entrainment patterns. Step-driven flows occurred at 1-2X step frequency with peak magnitudes of 0.97±0.45 Ls(-1) (mean ±S.D). Step-driven flows varied depending on ventilatory state (high versus low lung volume), suggesting state-dependent changes in compliance and damping of thoraco-abdominal tissues. Subjects naturally preferred LRC patterns that minimized antagonistic interactions and aligned ventilatory transitions with assistive phases of the step. Ventilatory transitions initiated in 'preferred' phases within the step cycle occurred 2x faster than those in 'avoided' phases. We hypothesize that humans coordinate breathing and locomotion to minimize antagonistic loading of respiratory muscles, reduce work of breathing and minimize rate of fatigue. Future work could address the potential consequences of

  13. Perspective: Insight into reaction coordinates and dynamics from the potential energy landscape

    SciTech Connect

    Wales, D. J.

    2015-04-07

    This perspective focuses on conceptual and computational aspects of the potential energy landscape framework. It has two objectives: first to summarise some key developments of the approach and second to illustrate how such techniques can be applied using a specific example that exploits knowledge of pathways. Recent developments in theory and simulation within the landscape framework are first outlined, including methods for structure prediction, analysis of global thermodynamic properties, and treatment of rare event dynamics. We then develop a connection between the kinetic transition network treatment of dynamics and a potential of mean force defined by a reaction coordinate. The effect of projection from the full configuration space to low dimensionality is illustrated for an atomic cluster. In this example, where a relatively successful structural order parameter is available, the principal change in cluster morphology is reproduced, but some details are not faithfully represented. In contrast, a profile based on configurations that correspond to the discrete path defined geometrically retains all the barriers and minima. This comparison provides insight into the physical origins of “friction” effects in low-dimensionality descriptions of dynamics based upon a reaction coordinate.

  14. Perspective: Insight into reaction coordinates and dynamics from the potential energy landscape

    NASA Astrophysics Data System (ADS)

    Wales, D. J.

    2015-04-01

    This perspective focuses on conceptual and computational aspects of the potential energy landscape framework. It has two objectives: first to summarise some key developments of the approach and second to illustrate how such techniques can be applied using a specific example that exploits knowledge of pathways. Recent developments in theory and simulation within the landscape framework are first outlined, including methods for structure prediction, analysis of global thermodynamic properties, and treatment of rare event dynamics. We then develop a connection between the kinetic transition network treatment of dynamics and a potential of mean force defined by a reaction coordinate. The effect of projection from the full configuration space to low dimensionality is illustrated for an atomic cluster. In this example, where a relatively successful structural order parameter is available, the principal change in cluster morphology is reproduced, but some details are not faithfully represented. In contrast, a profile based on configurations that correspond to the discrete path defined geometrically retains all the barriers and minima. This comparison provides insight into the physical origins of "friction" effects in low-dimensionality descriptions of dynamics based upon a reaction coordinate.

  15. Selective Adsorption of CO2 from Light Gas Mixtures Using a Structurally Dynamic Porous Coordination Polymer**

    SciTech Connect

    Kristi L. Kauffman, Jeffrey T. Culp, Andrew J. Allen, Laura Espinal, Winnie Wong-Ng, Thomas D. Brown, Angela Goodman, Mark P. Bernardo, Russel J. Pancoast, Danielle Chirdon, Christopher Matranga*

    2010-01-01

    The selective adsorption of CO{sub 2} from mixtures with N{sub 2}, CH{sub 4}, and N{sub 2}O in a dynamic porous coordination polymer (see monomer structure) was evaluated by ATR-FTIR spectroscopy, GC, and SANS. All three techniques indicate highly selective adsorption of CO{sub 2} from CO{sub 2}/CH{sub 4} and CO{sub 2}/N{sub 2} mixtures at 30 C, with no selectivity observed for the CO{sub 2}/N{sub 2}O system.

  16. Tortoise Coordinates and Hawking Radiation in a Dynamical Spherically Symmetric Spacetime

    NASA Astrophysics Data System (ADS)

    Yang, Jian; Zhao, Zheng; Tian, Gui-Hua; Liu, Wen-Biao

    2009-12-01

    Hawking effect from dynamical spherical Vaidya black hole, Vaidya-Bonner black hole, and Vaidya-de Sitter black hole is investigated using the improved Damour-Ruffini method. After the new tortoise coordinate transformation in which the position r of event horizon is an undetermined function and the temperature parameter κ is an undetermined constant, the Klein-Gordon equation can be written as the standard form at the event horizon, and both r and κ can be determined automatically. Then extending the outgoing wave from outside to inside of the horizon analytically, the Hawking temperature can also be obtained automatically.

  17. High resolution kinetic beam schemes in generalized coordinates for ideal quantum gas dynamics

    SciTech Connect

    Shi, Yu-Hsin; Huang, J.C.; Yang, J.Y. . E-mail: yangjy@iam.ntu.edu.tw

    2007-03-20

    A class of high resolution kinetic beam schemes in multiple space dimensions in general coordinates system for the ideal quantum gas is presented for the computation of quantum gas dynamical flows. The kinetic Boltzmann equation approach is adopted and the local equilibrium quantum statistics distribution is assumed. High-order accurate methods using essentially non-oscillatory interpolation concept are constructed. Computations of shock wave diffraction by a circular cylinder in an ideal quantum gas are conducted to illustrate the present method. The present method provides a viable means to explore various practical ideal quantum gas flows.

  18. High dynamic range charge measurements

    DOEpatents

    De Geronimo, Gianluigi

    2012-09-04

    A charge amplifier for use in radiation sensing includes an amplifier, at least one switch, and at least one capacitor. The switch selectively couples the input of the switch to one of at least two voltages. The capacitor is electrically coupled in series between the input of the amplifier and the input of the switch. The capacitor is electrically coupled to the input of the amplifier without a switch coupled therebetween. A method of measuring charge in radiation sensing includes selectively diverting charge from an input of an amplifier to an input of at least one capacitor by selectively coupling an output of the at least one capacitor to one of at least two voltages. The input of the at least one capacitor is operatively coupled to the input of the amplifier without a switch coupled therebetween. The method also includes calculating a total charge based on a sum of the amplified charge and the diverted charge.

  19. Simultaneous determination of the free energy profile and effective dynamics along a reaction coordinate

    NASA Astrophysics Data System (ADS)

    Zhang, Jiong; Kosztin, Ioan

    2015-03-01

    Often one can gain insight into the functioning of a biomolecular system by following its dynamics along a relevant reaction coordinate (RC). A proper description of the motion along the RC requires not only the determination of the corresponding free energy profile (PMF) but also the correct identification of the underlying stochastic model. While there exist several methods for determining the PMF from fast non-equilibrium pulling processes, for simplicity it is implicitly assumed that the dynamics along the RC is a simple overdamped Brownian motion with known diffusion coefficient. However, in general, the dynamics along the RC is non-Markovian that can be modeled with a generalized Langevin equation characterized by a friction memory kernel. Here we propose and demonstrate a method that permits the simultaneous determination of both PMF and friction memory kernel from fast bi-directional (forward and time-reversed) pulling processes. As a result, one can determine whether the diffusion along the RC is normal or anomalous (e.g., subdiffusion). The proposed method provides a novel approach for identifying and characterizing the effective dynamics along a RC of a biomolecular system studied by either single-molecule force microscopy or steered molecular dynamics simulations. Computer time was provided by the University of Missouri Bioinformatics Consortium.

  20. Research on large spatial coordinate automatic measuring system based on multilateral method

    NASA Astrophysics Data System (ADS)

    Miao, Dongjing; Li, Jianshuan; Li, Lianfu; Jiang, Yuanlin; Kang, Yao; He, Mingzhao; Deng, Xiangrui

    2015-10-01

    To measure the spatial coordinate accurately and efficiently in large size range, a manipulator automatic measurement system which based on multilateral method is developed. This system is divided into two parts: The coordinate measurement subsystem is consists of four laser tracers, and the trajectory generation subsystem is composed by a manipulator and a rail. To ensure that there is no laser beam break during the measurement process, an optimization function is constructed by using the vectors between the laser tracers measuring center and the cat's eye reflector measuring center, then an orientation automatically adjust algorithm for the reflector is proposed, with this algorithm, the laser tracers are always been able to track the reflector during the entire measurement process. Finally, the proposed algorithm is validated by taking the calibration of laser tracker for instance: the actual experiment is conducted in 5m × 3m × 3.2m range, the algorithm is used to plan the orientations of the reflector corresponding to the given 24 points automatically. After improving orientations of some minority points with adverse angles, the final results are used to control the manipulator's motion. During the actual movement, there are no beam break occurs. The result shows that the proposed algorithm help the developed system to measure the spatial coordinates over a large range with efficiency.

  1. Coordinated Action of Fast and Slow Reserves for Optimal Sequential and Dynamic Emergency Reserve Activation

    NASA Astrophysics Data System (ADS)

    Salkuti, Surender Reddy; Bijwe, P. R.; Abhyankar, A. R.

    2016-04-01

    This paper proposes an optimal dynamic reserve activation plan after the occurrence of an emergency situation (generator/transmission line outage, load increase or both). An optimal plan is developed to handle the emergency situation, using coordinated action of fast and slow reserves, for secure operation with minimum overall cost. This paper considers the reserves supplied by generators (spinning reserves) and loads (demand-side reserves). The optimal backing down of costly/fast reserves and bringing up of slow reserves in each sub-interval in an integrated manner is proposed. The simulation studies are performed on IEEE 30, 57 and 300 bus test systems to demonstrate the advantage of proposed integrated/dynamic reserve activation plan over the conventional/sequential approach.

  2. Bio-Inspired Composite Interfaces: Controlling Hydrogel Mechanics via Polymer-Nanoparticle Coordination Bond Dynamics

    NASA Astrophysics Data System (ADS)

    Holten-Andersen, Niels

    2015-03-01

    In soft nanocomposite materials, the effective interaction between polymer molecules and inorganic nanoparticle surfaces plays a critical role in bulk mechanical properties. However, controlling these interfacial interactions remains a challenge. Inspired by the adhesive chemistry in mussel threads, we present a novel approach to control composite mechanics via polymer-particle interfacial dynamics; by incorporating iron oxide nanoparticles (Fe3O4 NPs) into a catechol-modified polymer network the resulting hydrogels are crosslinked via reversible coordination bonds at Fe3O4 NP surfaces thereby providing a dynamic gel network with robust self-healing properties. By studying the thermally activated composite network relaxation processes we have found that the polymer-NP binding energy can be controlled by engineering both the organic and inorganic side of the interface.

  3. Control of hierarchical polymer mechanics with bioinspired metal-coordination dynamics

    NASA Astrophysics Data System (ADS)

    Grindy, Scott C.; Learsch, Robert; Mozhdehi, Davoud; Cheng, Jing; Barrett, Devin G.; Guan, Zhibin; Messersmith, Phillip B.; Holten-Andersen, Niels

    2015-12-01

    In conventional polymer materials, mechanical performance is traditionally engineered via material structure, using motifs such as polymer molecular weight, polymer branching, or block copolymer design. Here, by means of a model system of 4-arm poly(ethylene glycol) hydrogels crosslinked with multiple, kinetically distinct dynamic metal-ligand coordinate complexes, we show that polymer materials with decoupled spatial structure and mechanical performance can be designed. By tuning the relative concentration of two types of metal-ligand crosslinks, we demonstrate control over the material’s mechanical hierarchy of energy-dissipating modes under dynamic mechanical loading, and therefore the ability to engineer a priori the viscoelastic properties of these materials by controlling the types of crosslinks rather than by modifying the polymer itself. This strategy to decouple material mechanics from structure is general and may inform the design of soft materials for use in complex mechanical environments. Three examples that demonstrate this are provided.

  4. GneimoSim: A Modular Internal Coordinates Molecular Dynamics Simulation Package

    PubMed Central

    Larsen, Adrien B.; Wagner, Jeffrey R.; Kandel, Saugat; Salomon-Ferrer, Romelia; Vaidehi, Nagarajan; Jain, Abhinandan

    2014-01-01

    The Generalized Newton Euler Inverse Mass Operator (GNEIMO) method is an advanced method for internal coordinates molecular dynamics (ICMD). GNEIMO includes several theoretical and algorithmic advancements that address longstanding challenges with ICMD simulations. In this paper we describe the GneimoSim ICMD software package that implements the GNEIMO method. We believe that GneimoSim is the first software package to include advanced features such as the equipartition principle derived for internal coordinates, and a method for including the Fixman potential to eliminate systematic statistical biases introduced by the use of hard constraints. Moreover, by design, GneimoSim is extensible and can be easily interfaced with third party force field packages for ICMD simulations. Currently, GneimoSim includes interfaces to LAMMPS, OpenMM, Rosetta force field calculation packages. The availability of a comprehensive Python interface to the underlying C++ classes and their methods provides a powerful and versatile mechanism for users to develop simulation scripts to configure the simulation and control the simulation flow. GneimoSim has been used extensively for studying the dynamics of protein structures, refinement of protein homology models, and for simulating large scale protein conformational changes with enhanced sampling methods. GneimoSim is not limited to proteins and can also be used for the simulation of polymeric materials. PMID:25263538

  5. Overcoming potential energy distortions in constrained internal coordinate molecular dynamics simulations

    NASA Astrophysics Data System (ADS)

    Kandel, Saugat; Salomon-Ferrer, Romelia; Larsen, Adrien B.; Jain, Abhinandan; Vaidehi, Nagarajan

    2016-01-01

    The Internal Coordinate Molecular Dynamics (ICMD) method is an attractive molecular dynamics (MD) method for studying the dynamics of bonded systems such as proteins and polymers. It offers a simple venue for coarsening the dynamics model of a system at multiple hierarchical levels. For example, large scale protein dynamics can be studied using torsional dynamics, where large domains or helical structures can be treated as rigid bodies and the loops connecting them as flexible torsions. ICMD with such a dynamic model of the protein, combined with enhanced conformational sampling method such as temperature replica exchange, allows the sampling of large scale domain motion involving high energy barrier transitions. Once these large scale conformational transitions are sampled, all-torsion, or even all-atom, MD simulations can be carried out for the low energy conformations sampled via coarse grained ICMD to calculate the energetics of distinct conformations. Such hierarchical MD simulations can be carried out with standard all-atom forcefields without the need for compromising on the accuracy of the forces. Using constraints to treat bond lengths and bond angles as rigid can, however, distort the potential energy landscape of the system and reduce the number of dihedral transitions as well as conformational sampling. We present here a two-part solution to overcome such distortions of the potential energy landscape with ICMD models. To alleviate the intrinsic distortion that stems from the reduced phase space in torsional MD, we use the Fixman compensating potential. To additionally alleviate the extrinsic distortion that arises from the coupling between the dihedral angles and bond angles within a force field, we propose a hybrid ICMD method that allows the selective relaxing of bond angles. This hybrid ICMD method bridges the gap between all-atom MD and torsional MD. We demonstrate with examples that these methods together offer a solution to eliminate the potential

  6. Overcoming potential energy distortions in constrained internal coordinate molecular dynamics simulations.

    PubMed

    Kandel, Saugat; Salomon-Ferrer, Romelia; Larsen, Adrien B; Jain, Abhinandan; Vaidehi, Nagarajan

    2016-01-28

    The Internal Coordinate Molecular Dynamics (ICMD) method is an attractive molecular dynamics (MD) method for studying the dynamics of bonded systems such as proteins and polymers. It offers a simple venue for coarsening the dynamics model of a system at multiple hierarchical levels. For example, large scale protein dynamics can be studied using torsional dynamics, where large domains or helical structures can be treated as rigid bodies and the loops connecting them as flexible torsions. ICMD with such a dynamic model of the protein, combined with enhanced conformational sampling method such as temperature replica exchange, allows the sampling of large scale domain motion involving high energy barrier transitions. Once these large scale conformational transitions are sampled, all-torsion, or even all-atom, MD simulations can be carried out for the low energy conformations sampled via coarse grained ICMD to calculate the energetics of distinct conformations. Such hierarchical MD simulations can be carried out with standard all-atom forcefields without the need for compromising on the accuracy of the forces. Using constraints to treat bond lengths and bond angles as rigid can, however, distort the potential energy landscape of the system and reduce the number of dihedral transitions as well as conformational sampling. We present here a two-part solution to overcome such distortions of the potential energy landscape with ICMD models. To alleviate the intrinsic distortion that stems from the reduced phase space in torsional MD, we use the Fixman compensating potential. To additionally alleviate the extrinsic distortion that arises from the coupling between the dihedral angles and bond angles within a force field, we propose a hybrid ICMD method that allows the selective relaxing of bond angles. This hybrid ICMD method bridges the gap between all-atom MD and torsional MD. We demonstrate with examples that these methods together offer a solution to eliminate the potential

  7. Overcoming potential energy distortions in constrained internal coordinate molecular dynamics simulations.

    PubMed

    Kandel, Saugat; Salomon-Ferrer, Romelia; Larsen, Adrien B; Jain, Abhinandan; Vaidehi, Nagarajan

    2016-01-28

    The Internal Coordinate Molecular Dynamics (ICMD) method is an attractive molecular dynamics (MD) method for studying the dynamics of bonded systems such as proteins and polymers. It offers a simple venue for coarsening the dynamics model of a system at multiple hierarchical levels. For example, large scale protein dynamics can be studied using torsional dynamics, where large domains or helical structures can be treated as rigid bodies and the loops connecting them as flexible torsions. ICMD with such a dynamic model of the protein, combined with enhanced conformational sampling method such as temperature replica exchange, allows the sampling of large scale domain motion involving high energy barrier transitions. Once these large scale conformational transitions are sampled, all-torsion, or even all-atom, MD simulations can be carried out for the low energy conformations sampled via coarse grained ICMD to calculate the energetics of distinct conformations. Such hierarchical MD simulations can be carried out with standard all-atom forcefields without the need for compromising on the accuracy of the forces. Using constraints to treat bond lengths and bond angles as rigid can, however, distort the potential energy landscape of the system and reduce the number of dihedral transitions as well as conformational sampling. We present here a two-part solution to overcome such distortions of the potential energy landscape with ICMD models. To alleviate the intrinsic distortion that stems from the reduced phase space in torsional MD, we use the Fixman compensating potential. To additionally alleviate the extrinsic distortion that arises from the coupling between the dihedral angles and bond angles within a force field, we propose a hybrid ICMD method that allows the selective relaxing of bond angles. This hybrid ICMD method bridges the gap between all-atom MD and torsional MD. We demonstrate with examples that these methods together offer a solution to eliminate the potential

  8. A discussion of dynamic stability measurement techniques

    NASA Technical Reports Server (NTRS)

    Johnson, W.

    1975-01-01

    Techniques for the measurement of the dynamic stability of linear systems are discussed. Particular attention is given to an analysis of the errors in the procedures, and to methods for calculating the system damping from the data. The techniques discussed include: transient decay, moving block analysis, spectral analysis, random decrement signatures, transfer function analysis, and parameter identification methods. The special problems of rotorcraft dynamic stability testing are discussed.

  9. Effects of coordinate system choice on measured regional myocardial function in short-axis cine electron-beam tomography

    NASA Astrophysics Data System (ADS)

    Reed, Judd E.; Rumberger, John A.; Buithieu, Jean; Behrenbeck, Thomas; Breen, Jerome F.; Sheedy, Patrick F., II

    1995-05-01

    Following myocardial infarction, the size of the infarcted region and the systolic functioning of the noninfarcted region are commonly assessed by various cross- sectional imaging techniques. A series of images representing successive phases of the cardiac cycle can be acquired by several imaging modalities including electron beam computed tomography, magnetic resonance imaging, and echocardiography. For the assessment of patterns of ventricular contraction, images are commonly acquired of ventricular cross-sections normal to the 'long' axis of the heart and parallel to the mitral valve plane. The endocardial and epicardial surfaces of the myocardium are identified. Then the ventricle is divided into sectors and the volumes of blood and myocardium within each sector at multiple phases of the cardiac cycle are measured. Regional function parameters are derived from these measurements. This generally mandates the use of a polar or cylindrical coordinate system. Various algorithms have been used to select the origin of this coordinate system. These include the centroid of the endocardial surface, the epicardial surface, or of a polygon whose vertices lie midway between the epicardial and endocardial surfaces of the myocardium (centerline method). Another algorithm has been developed in our laboratory. This uses the centroid (or center of mass) of the myocardium exclusive of the ventricular cavity. Each of these choices for origin of coordinate system can be derived from the end- diastolic image or from the end-systolic image. Alternately, new coordinate systems can be selected for each phase of the cardiac cycle. These are referred to as 'floating' coordinate systems. A series of computer models have been developed in our laboratory to study the effects of each of these choices on the regional function parameters of normal ventricles and how these choices effect the quantification of regional abnormalities after myocardial infarction. The most sophisticated of these

  10. Bioinspired dynamic inclination measurement using inertial sensors.

    PubMed

    Vikas, Vishesh; Crane, Carl

    2015-04-16

    Biologically, the vestibular feedback is critical to the ability of human body to balance in different conditions. This balancing ability inspires analysis of the reference equilibrium position in dynamic environments. The research proposes and experimentally validates the concept of equilibrium for the human body modeled as an inverted pendulum, which is instrumental in explaining why we align the body along the surface normal when standing on a surface but not on an incline, and tend to lean backward or forward on non-static surfaces e.g. accelerating or decelerating bus. This equilibrium position--the dynamic equilibrium axis--is dependent only on the acceleration of surface of contact (e.g. gravity) and acts as the reference to the orientation measurements. The research also draws design inspiration from the two human ears--symmetry and plurality of inertial sensors. The vestibular dynamic inclinometer and planar vestibular dynamic inclinometer consist of multiple (two or four) symmetrically placed accelerometers and a gyroscope. The sensors measure the angular acceleration and absolute orientation, not the change in orientation, from the reference equilibrium position and are successful in separating gravity from motion for objects moving on ground. The measurement algorithm is an analytical solution that is not time-recursive, independent of body dynamics and devoid of integration errors. The experimental results for the two sensor combinations validate the theoretically (kinematics) derived analytical solution of the measurement algorithm.

  11. Bioinspired dynamic inclination measurement using inertial sensors.

    PubMed

    Vikas, Vishesh; Crane, Carl

    2015-06-01

    Biologically, the vestibular feedback is critical to the ability of human body to balance in different conditions. This balancing ability inspires analysis of the reference equilibrium position in dynamic environments. The research proposes and experimentally validates the concept of equilibrium for the human body modeled as an inverted pendulum, which is instrumental in explaining why we align the body along the surface normal when standing on a surface but not on an incline, and tend to lean backward or forward on non-static surfaces e.g. accelerating or decelerating bus. This equilibrium position--the dynamic equilibrium axis--is dependent only on the acceleration of surface of contact (e.g. gravity) and acts as the reference to the orientation measurements. The research also draws design inspiration from the two human ears--symmetry and plurality of inertial sensors. The vestibular dynamic inclinometer and planar vestibular dynamic inclinometer consist of multiple (two or four) symmetrically placed accelerometers and a gyroscope. The sensors measure the angular acceleration and absolute orientation, not the change in orientation, from the reference equilibrium position and are successful in separating gravity from motion for objects moving on ground. The measurement algorithm is an analytical solution that is not time-recursive, independent of body dynamics and devoid of integration errors. The experimental results for the two sensor combinations validate the theoretically (kinematics) derived analytical solution of the measurement algorithm. PMID:25879912

  12. The impact of Wii Fit intervention on dynamic balance control in children with probable Developmental Coordination Disorder and balance problems.

    PubMed

    Jelsma, Dorothee; Geuze, Reint H; Mombarg, Remo; Smits-Engelsman, Bouwien C M

    2014-02-01

    The aim of this study was to examine differences in the performance of children with probable Developmental Coordination Disorder (p-DCD) and balance problems (BP) and typical developing children (TD) on a Wii Fit task and to measure the effect on balance skills after a Wii Fit intervention. Twenty-eight children with BP and 20 TD-children participated in the study. Motor performance was assessed with the Movement Assessment Battery for Children (MABC2), three subtests of the Bruininks Oseretsky Test (BOT2): Bilateral Coordination, Balance and Running Speed & Agility, and a Wii Fit ski slalom test. The TD children and half of the children in the BP group were tested before and after a 6weeks non-intervention period. All children with BP received 6weeks of Wii Fit intervention (with games other than the ski game) and were tested before and afterwards. Children with BP were less proficient than TD children in playing the Wii Fit ski slalom game. Training with the Wii Fit improved their motor performance. The improvement was significantly larger after intervention than after a period of non-intervention. Therefore the change cannot solely be attributed to spontaneous development or test-retest effect. Nearly all children enjoyed participation during the 6weeks of intervention. Our study shows that Wii Fit intervention is effective and is potentially a method to support treatment of (dynamic) balance control problems in children. PMID:24444657

  13. Computing the Free Energy along a Reaction Coordinate Using Rigid Body Dynamics.

    PubMed

    Tao, Peng; Sodt, Alexander J; Shao, Yihan; König, Gerhard; Brooks, Bernard R

    2014-10-14

    The calculations of potential of mean force along complex chemical reactions or rare events pathways are of great interest because of their importance for many areas in chemistry, molecular biology, and material science. The major difficulty for free energy calculations comes from the great computational cost for adequate sampling of the system in high-energy regions, especially close to the reaction transition state. Here, we present a method, called FEG-RBD, in which the free energy gradients were obtained from rigid body dynamics simulations. Then the free energy gradients were integrated along a reference reaction pathway to calculate free energy profiles. In a given system, the reaction coordinates defining a subset of atoms (e.g., a solute, or the quantum mechanics (QM) region of a quantum mechanics/molecular mechanics simulation) are selected to form a rigid body during the simulation. The first-order derivatives (gradients) of the free energy with respect to the reaction coordinates are obtained through the integration of constraint forces within the rigid body. Each structure along the reference reaction path is separately subjected to such a rigid body simulation. The individual free energy gradients are integrated along the reference pathway to obtain the free energy profile. Test cases provided demonstrate both the strengths and weaknesses of the FEG-RBD method. The most significant benefit of this method comes from the fast convergence rate of the free energy gradient using rigid-body constraints instead of restraints. A correction to the free energy due to approximate relaxation of the rigid-body constraint is estimated and discussed. A comparison with umbrella sampling using a simple test case revealed the improved sampling efficiency of FEG-RBD by a factor of 4 on average. The enhanced efficiency makes this method effective for calculating the free energy of complex chemical reactions when the reaction coordinate can be unambiguously defined by a

  14. Decipher the dynamic coordination between enzymatic activity and structural modulation at focal adhesions in living cells

    NASA Astrophysics Data System (ADS)

    Lu, Shaoying; Seong, Jihye; Wang, Yi; Chang, Shiou-Chi; Eichorst, John Paul; Ouyang, Mingxing; Li, Julie Y.-S.; Chien, Shu; Wang, Yingxiao

    2014-07-01

    Focal adhesions (FAs) are dynamic subcellular structures crucial for cell adhesion, migration and differentiation. It remains an enigma how enzymatic activities in these local complexes regulate their structural remodeling in live cells. Utilizing biosensors based on fluorescence resonance energy transfer (FRET), we developed a correlative FRET imaging microscopy (CFIM) approach to quantitatively analyze the subcellular coordination between the enzymatic Src activation and the structural FA disassembly. CFIM reveals that the Src kinase activity only within the microdomain of lipid rafts at the plasma membrane is coupled with FA dynamics. FA disassembly at cell periphery was linearly dependent on this raft-localized Src activity, although cells displayed heterogeneous levels of response to stimulation. Within lipid rafts, the time delay between Src activation and FA disassembly was 1.2 min in cells seeded on low fibronectin concentration ([FN]) and 4.3 min in cells on high [FN]. CFIM further showed that the level of Src-FA coupling, as well as the time delay, was regulated by cell-matrix interactions, as a tight enzyme-structure coupling occurred in FA populations mediated by integrin αvβ3, but not in those by integrin α5β1. Therefore, different FA subpopulations have distinctive regulation mechanisms between their local kinase activity and structural FA dynamics.

  15. Decipher the dynamic coordination between enzymatic activity and structural modulation at focal adhesions in living cells.

    PubMed

    Lu, Shaoying; Seong, Jihye; Wang, Yi; Chang, Shiou-chi; Eichorst, John Paul; Ouyang, Mingxing; Li, Julie Y-S; Chien, Shu; Wang, Yingxiao

    2014-01-01

    Focal adhesions (FAs) are dynamic subcellular structures crucial for cell adhesion, migration and differentiation. It remains an enigma how enzymatic activities in these local complexes regulate their structural remodeling in live cells. Utilizing biosensors based on fluorescence resonance energy transfer (FRET), we developed a correlative FRET imaging microscopy (CFIM) approach to quantitatively analyze the subcellular coordination between the enzymatic Src activation and the structural FA disassembly. CFIM reveals that the Src kinase activity only within the microdomain of lipid rafts at the plasma membrane is coupled with FA dynamics. FA disassembly at cell periphery was linearly dependent on this raft-localized Src activity, although cells displayed heterogeneous levels of response to stimulation. Within lipid rafts, the time delay between Src activation and FA disassembly was 1.2 min in cells seeded on low fibronectin concentration ([FN]) and 4.3 min in cells on high [FN]. CFIM further showed that the level of Src-FA coupling, as well as the time delay, was regulated by cell-matrix interactions, as a tight enzyme-structure coupling occurred in FA populations mediated by integrin αvβ₃, but not in those by integrin α₅β₁. Therefore, different FA subpopulations have distinctive regulation mechanisms between their local kinase activity and structural FA dynamics.

  16. Measuring Dynamic Transfer Functions of Cavitating Pumps

    NASA Technical Reports Server (NTRS)

    Baun, Daniel

    2007-01-01

    A water-flow test facility has been built to enable measurement of dynamic transfer functions (DTFs) of cavitating pumps and of inducers in such pumps. Originally, the facility was intended for use in an investigation of the effects of cavitation in a rocket-engine low-pressure oxygen turbopump. The facility can also be used to measure DTFs of cavitating pumps in general

  17. A Dynamical Model of Hierarchical Selection and Coordination in Speech Planning

    PubMed Central

    Tilsen, Sam

    2013-01-01

    Studies of the control of complex sequential movements have dissociated two aspects of movement planning: control over the sequential selection of movement plans, and control over the precise timing of movement execution. This distinction is particularly relevant in the production of speech: utterances contain sequentially ordered words and syllables, but articulatory movements are often executed in a non-sequential, overlapping manner with precisely coordinated relative timing. This study presents a hybrid dynamical model in which competitive activation controls selection of movement plans and coupled oscillatory systems govern coordination. The model departs from previous approaches by ascribing an important role to competitive selection of articulatory plans within a syllable. Numerical simulations show that the model reproduces a variety of speech production phenomena, such as effects of preparation and utterance composition on reaction time, and asymmetries in patterns of articulatory timing associated with onsets and codas. The model furthermore provides a unified understanding of a diverse group of phonetic and phonological phenomena which have not previously been related. PMID:23638147

  18. Coordinating two-period ordering and advertising policies in a dynamic market with stochastic demand

    NASA Astrophysics Data System (ADS)

    Wang, Junping; Wang, Shengdong; Min, Jie

    2015-03-01

    In this paper, we study the optimal two-stage advertising and ordering policies and the channel coordination issues in a supply chain composed of one manufacturer and one retailer. The manufacturer sells a short-life-cycle product through the retailer facing stochastic demand in dynamic markets characterised by price declines and product obsolescence. Following a two-period newsvendor framework, we develop two members' optimal ordering and advertising models under both the centralised and decentralised settings, and present the closed-form solutions to the developed models as well. Moreover, we design a two-period revenue-sharing contract, and develop sufficient conditions such that the channel coordination can be achieved and a win-win outcome can be guaranteed. Our analysis suggests that the centralised decision creates an incentive for the retailer to increase the advertising investments in two periods and put the purchase forward, but the decentralised decision mechanism forces the retailer to decrease the advertising investments in two periods and postpone/reduce its purchase in the first period. This phenomenon becomes more evident when demand variability is high.

  19. Measuring Group Dynamics: An Exploratory Trial

    ERIC Educational Resources Information Center

    Phan, Loan T.; Rivera, Edil Torres; Volker, Martin A.; Garrett, Michael T.

    2004-01-01

    This article reports on the development of a scale used to assess and measure group dynamics during group supervision counselling courses (practicum and internship). A 20-item Likert-type scale was administered to 200 counsellors-in-training master's students. Reliability and validity data are described. An exploratory factor analysis yielded…

  20. Modification of the Sandia National Laboratories/California advanced coordinate measuring machine for high speed scanning

    SciTech Connect

    Baldwin, J.M.; Pilkey, R.D.; Cassou, R.M.; Summerhays, K.D.

    1997-03-01

    The Moore M48V high accuracy coordinate measuring machine (CMM), while mechanically capable of exact measurement of physical artifacts, is not, in its original configuration, well suited for rapid gathering of high density dimensional information. This report describes hardware and software modifications to the original control and data acquisition system that allow relatively high speed scanning of cylindrical features. We also estimate the accuracy of the individual point data on artifacts measured with this system and provide detailed descriptions of the hardware and software apparatus as an aid to others who may wish to apply the system to cylindrical or other simple geometries. 6 refs., 18 figs., 1 tab.

  1. Oscillatory dynamics coordinating human frontal networks in support of goal maintenance.

    PubMed

    Voytek, Bradley; Kayser, Andrew S; Badre, David; Fegen, David; Chang, Edward F; Crone, Nathan E; Parvizi, Josef; Knight, Robert T; D'Esposito, Mark

    2015-09-01

    Humans have a capacity for hierarchical cognitive control-the ability to simultaneously control immediate actions while holding more abstract goals in mind. Neuropsychological and neuroimaging evidence suggests that hierarchical cognitive control emerges from a frontal architecture whereby prefrontal cortex coordinates neural activity in the motor cortices when abstract rules are needed to govern motor outcomes. We utilized the improved temporal resolution of human intracranial electrocorticography to investigate the mechanisms by which frontal cortical oscillatory networks communicate in support of hierarchical cognitive control. Responding according to progressively more abstract rules resulted in greater frontal network theta phase encoding (4-8 Hz) and increased prefrontal local neuronal population activity (high gamma amplitude, 80-150 Hz), which predicts trial-by-trial response times. Theta phase encoding coupled with high gamma amplitude during inter-regional information encoding, suggesting that inter-regional phase encoding is a mechanism for the dynamic instantiation of complex cognitive functions by frontal cortical subnetworks. PMID:26214371

  2. Event heap: a coordination infrastructure for dynamic heterogeneous application interactions in ubiquitous computing environments

    DOEpatents

    Johanson, Bradley E.; Fox, Armando; Winograd, Terry A.; Hanrahan, Patrick M.

    2010-04-20

    An efficient and adaptive middleware infrastructure called the Event Heap system dynamically coordinates application interactions and communications in a ubiquitous computing environment, e.g., an interactive workspace, having heterogeneous software applications running on various machines and devices across different platforms. Applications exchange events via the Event Heap. Each event is characterized by a set of unordered, named fields. Events are routed by matching certain attributes in the fields. The source and target versions of each field are automatically set when an event is posted or used as a template. The Event Heap system implements a unique combination of features, both intrinsic to tuplespaces and specific to the Event Heap, including content based addressing, support for routing patterns, standard routing fields, limited data persistence, query persistence/registration, transparent communication, self-description, flexible typing, logical/physical centralization, portable client API, at most once per source first-in-first-out ordering, and modular restartability.

  3. Dynamics of the 1054 UT March 22, 1979, substorm event - CDAW 6. [Coordinated Data Analysis Workshop

    NASA Technical Reports Server (NTRS)

    Mcpherron, R. L.; Manka, R. H.

    1985-01-01

    The Coordinated Data Analysis Workshop (CDAW 6) has the primary objective to trace the flow of energy from the solar wind through the magnetosphere to its ultimate dissipation in the ionosphere. An essential role in this energy transfer is played by magnetospheric substorms, however, details are not yet completely understood. The International Magnetospheric Study (IMS) has provided an ideal data base for the study conducted by CDAW 6. The present investigation is concerned with the 1054 UT March 22, 1979, substorm event, which had been selected for detailed examination in connection with the studies performed by the CDAW 6. The observations of this substorm are discussed, taking into account solar wind conditions, ground magnetic activity on March 22, 1979, observations at synchronous orbit, observations in the near geomagnetic tail, and the onset of the 1054 UT expansion phase. Substorm development and magnetospheric dynamics are discussed on the basis of a synthesis of the observations.

  4. High-order kinetic flux vector splitting schemes in general coordinates for ideal quantum gas dynamics

    SciTech Connect

    Yang, J.-Y. Hsieh, T.-Y.; Shi, Y.-H.; Xu Kun

    2007-12-10

    A class of high-order kinetic flux vector splitting schemes are presented for solving ideal quantum gas dynamics based on quantum statistical mechanics. The collisionless quantum Boltzmann equation approach is adopted and both Bose-Einstein and Fermi-Dirac gases are considered. The formulas for the split flux vectors are derived based on the general three-dimensional distribution function in velocity space and formulas for lower dimensions can be directly deduced. General curvilinear coordinates are introduced to treat practical problems with general geometry. High-order accurate schemes using weighted essentially non-oscillatory methods are implemented. The resulting high resolution kinetic flux splitting schemes are tested for 1D shock tube flows and shock wave diffraction by a 2D wedge and by a circular cylinder in ideal quantum gases. Excellent results have been obtained for all examples computed.

  5. Transient Raman observations of heme vibrational dynamics in five-coordinate iron porphyrins

    NASA Astrophysics Data System (ADS)

    Loparo, Joseph J.; Cheatum, Christopher M.; Ondrias, Mark R.; Simpson, M. Cather

    2003-01-01

    Transient resonance Raman spectroscopy has been used to study vibrational dynamics in five-coordinate, high-spin Fe II octaethyl porphyrin with a 2-methyl imidazole axial ligand. Vibrational populations of the porphyrin ground electronic state were probed by examining Stokes and anti-Stokes Raman scattering as a function of incident laser flux using ˜10 nanosecond pulses in resonance with the Soret electronic transition. Within a single pulse, each molecule goes through several excitation-decay cycles, building up a non-equilibrium, excited vibrational energy distribution that is exquisitely sensitive to the vibrational mode lifetimes and to the incident laser flux. A kinetic model illustrates these ideas and provides strong support for the interpretation of the results. The flux dependence of the Raman intensities, positions and linewidths suggests that ν3 and ν4 act as "bottleneck" vibrational states, while νCH and ν7 couple more effectively to the environment.

  6. Oscillatory dynamics coordinating human frontal networks in support of goal maintenance

    PubMed Central

    Voytek, Bradley; Kayser, Andrew S.; Badre, David; Fegen, David; Chang, Edward F.; Crone, Nathan E.; Parvizi, Josef; Knight, Robert T.; D'Esposito, Mark

    2015-01-01

    Humans have a capacity for hierarchical cognitive control—the ability to simultaneously control immediate actions while holding more abstract goals in mind. Neuropsychological and neuroimaging evidence suggests that hierarchical cognitive control emerges from a frontal architecture whereby prefrontal cortex coordinates neural activity in the motor cortices when abstract rules are needed to govern motor outcomes. Here we utilize the improved temporal resolution of human intracranial electrocorticography to investigate the mechanisms by which frontal cortical oscillatory networks communicate in support of hierarchical cognitive control. Responding according to progressively more abstract rules results in greater frontal network theta phase encoding (4-8 Hz) and increased prefrontal local neuronal population activity (high gamma amplitude, 80-150 Hz), which predicts trial-by-trial response times. Theta phase encoding couples with high gamma amplitude during interregional information encoding, suggesting that interregional phase encoding is a mechanism for the dynamic instantiation of complex cognitive functions by frontal cortical subnetworks. PMID:26214371

  7. 75 FR 5343 - In the Matter of Certain Articulated Coordinate Measuring Arms and Components Thereof; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ... coordinate measuring arms or components thereof by reason of infringement of certain claims of U.S. Patent No. 5,829,148. 74 FR 44384-85 (August 28, 2009). The complainant named Metris N.V. of Leuven, Belgium... COMMISSION In the Matter of Certain Articulated Coordinate Measuring Arms and Components Thereof; Notice of...

  8. The Method of Measurements of Celestial Coordinates in Wide-Field TV-Frames

    NASA Astrophysics Data System (ADS)

    Kartashova, Anna P.

    2012-06-01

    We present a method for calculations of equatorial coordinates of any point in the single frame of the wide-field TV systems. This method can be applying for the different television systems [wide-field cameras, all-sky cameras, the cameras with the hybrid TV-system (the system with coupled of the Image Intensifier) et al.]. In that system the calculations of distortions are difficult. Therefore, we devised this method which helps decrease errors (due to distortion and the electro-optical system).The method can be used for measuring of equatorial coordinates of meteor tracks under difficult conditions during the observations such as partial cloudiness, small number of stars and large distortions of the coordinate grid in the frame. These restrictions cannot be overcome by other methods. In the case of the small number of stars the present method using of the reference stars received on a series of frames during the observation period. The accuracy of the method has been estimated to be 4'-8' (for cameras with fov 50° × 40° at the CCD 720 × 576 pixels) for maximum number of reference points in the frame. The method used 3 reference points for calculation of the equatorial coordinates of the object. One can use this method if the camera was re-oriented as well. We use this method for our wide field of view cameras.

  9. Dynamic hyperinflation: is it worth measuring?

    PubMed

    Calverley, Peter M A

    2006-05-01

    A reduced exercise capacity is an important determinant of health status and an independent prognostic marker in patients with chronic obstructive pulmonary disease. The inability to increase expiratory flow at the resting end-expiratory lung volume in the face of expiratory-flow limitation means that end-expiratory lung volume must increase if gas exchange is to be maintained near normal values. This phenomenon is usually referred to as dynamic hyperinflation. The change in operating lung volumes during exercise is related to the intensity of breathlessness. Treatments such as bronchodilators that increase inspiratory capacity or supplemental oxygen, which reduces ventilatory demand, decrease the degree of dynamic hyperinflation at any external workload. However, dynamic hyperinflation is not seen universally in patients with chronic obstructive pulmonary disease as some adopt different breathing patterns when they exercise, or respond to inhaled bronchodilators by changing their pattern of abdominal muscle activation, a behavior that can be counterproductive. Finally, dynamic hyperinflation can be reduced when, for example, breathing oxygen after exercise without changes in dyspnea, as other factors are more important determinants of this symptom in these circumstances. Dynamic hyperinflation can be reliably measured from the inspiratory capacity maneuver in many laboratories. Although knowledge about this variable gives great insight into the mechanisms of therapy, its routine measurement cannot currently be recommended as it does not appear to add additional clinical data beyond those available in present laboratory exercise testing protocols.

  10. The effect of coordinate system choice and segment reference on RSA-based knee translation measures.

    PubMed

    Beardsley, Christina L; Paller, David J; Peura, Glenn D; Brattbakk, Bjarne; Beynnon, Bruce D

    2007-01-01

    Roentgen stereophotogrammetric analysis (RSA) can be utilized to accurately describe joint kinematics, but even when measuring small displacements within radiographically discernible structures, standardized reference frames are imperative for useful comparison across patients and across studies. In the current paper, accurately controlled laboratory models demonstrated the considerable influence that a mere 1.9-cm offset of the origin of the coordinate system from the rotation axes could exert on translation measures when rotations were occurring. In addition, the use of two different coordinate systems to gauge translation on a radiographic anterior-posterior (A-P) knee laxity exam resulted in a significant correlation (R(2)=0.562) between the two systems; however, differences of up 9.28 mm were found between corresponding measurements. This implies that clinical conclusions can potentially be upheld or refuted, based on the same data set, subject to coordinate system definition. Although the data analyzed presently involved the knee joint, similar issues surround the RSA motion analysis of other joints as well.

  11. Use of global positioning system measurements to determine geocentric coordinates and variations in Earth orientation

    NASA Technical Reports Server (NTRS)

    Malla, R. P.; Wu, S.-C.; Lichten, S. M.

    1993-01-01

    Geocentric tracking station coordinates and short-period Earth-orientation variations can be measured with Global Positioning System (GPS) measurements. Unless calibrated, geocentric coordinate errors and changes in Earth orientation can lead to significant deep-space tracking errors. Ground-based GPS estimates of daily and subdaily changes in Earth orientation presently show centimeter-level precision. Comparison between GPS-estimated Earth-rotation variations, which are the differences between Universal Time 1 and Universal Coordinated Time (UT1-UTC), and those calculated from ocean tide models suggests that observed subdaily variations in Earth rotation are dominated by oceanic tidal effects. Preliminary GPS estimates for the geocenter location (from a 3-week experiment) agree with independent satellite laser-ranging estimates to better than 10 cm. Covariance analysis predicts that temporal resolution of GPS estimates for Earth orientation and geocenter improves significantly when data collected from low Earth-orbiting satellites as well as from ground sites are combined. The low Earth GPS tracking data enhance the accuracy and resolution for measuring high-frequency global geodynamical signals over time scales of less than 1 day.

  12. Transient dynamics and rhythm coordination of inferior olive spatio-temporal patterns.

    PubMed

    Latorre, Roberto; Aguirre, Carlos; Rabinovich, Mikhail I; Varona, Pablo

    2013-01-01

    The inferior olive (IO) is a neural network belonging to the olivo-cerebellar system whose neurons are coupled with electrical synapses and display subthreshold oscillations and spiking activity. The IO is frequently proposed as the generator of timing signals to the cerebellum. Electrophysiological and imaging recordings show that the IO network generates complex spatio-temporal patterns. The generation and modulation of coherent spiking activity in the IO is one key issue in cerebellar research. In this work, we build a large scale IO network model of electrically coupled conductance-based neurons to study the emerging spatio-temporal patterns of its transient neuronal activity. Our modeling reproduces and helps to understand important phenomena observed in IO in vitro and in vivo experiments, and draws new predictions regarding the computational properties of this network and the associated cerebellar circuits. The main factors studied governing the collective dynamics of the IO network were: the degree of electrical coupling, the extent of the electrotonic connections, the presence of stimuli or regions with different excitability levels and the modulatory effect of an inhibitory loop (IL). The spatio-temporal patterns were analyzed using a discrete wavelet transform to provide a quantitative characterization. Our results show that the electrotonic coupling produces quasi-synchronized subthreshold oscillations over a wide dynamical range. The synchronized oscillatory activity plays the role of a timer for a coordinated representation of spiking rhythms with different frequencies. The encoding and coexistence of several coordinated rhythms is related to the different clusterization and coherence of transient spatio-temporal patterns in the network, where the spiking activity is commensurate with the quasi-synchronized subthreshold oscillations. In the presence of stimuli, different rhythms are encoded in the spiking activity of the IO neurons that nevertheless

  13. Distance measures for dynamic citation networks

    NASA Astrophysics Data System (ADS)

    Bommarito, Michael J.; Katz, Daniel Martin; Zelner, Jonathan L.; Fowler, James H.

    2010-10-01

    Acyclic digraphs arise in many natural and artificial processes. Among the broader set, dynamic citation networks represent an important type of acyclic digraph. For example, the study of such networks includes the spread of ideas through academic citations, the spread of innovation through patent citations, and the development of precedent in common law systems. The specific dynamics that produce such acyclic digraphs not only differentiate them from other classes of graphs, but also provide guidance for the development of meaningful distance measures. In this article, we develop and apply our sink distance measure together with the single-linkage hierarchical clustering algorithm to both a two-dimensional directed preferential attachment model as well as empirical data drawn from the first quarter-century of decisions of the United States Supreme Court. Despite applying the simplest combination of distance measure and clustering algorithm, analysis reveals that more accurate and more interpretable clusterings are produced by this scheme.

  14. EB1-recruited microtubule +TIP complexes coordinate protrusion dynamics during 3D epithelial remodeling

    PubMed Central

    Gierke, Sarah; Wittmann, Torsten

    2012-01-01

    SUMMARY Background Epithelial remodeling, in which apical-basal polarized cells switch to a migratory phenotype, plays a central role in development and disease of multicellular organisms. Although dynamic microtubules (MTs) are required for directed migration on flat surfaces, how MT dynamics are controlled or contribute to epithelial remodeling in a more physiological three-dimensional (3D) environment is not understood. We use confocal live cell imaging to analyze MT function and dynamics during 3D epithelial morphogenesis and remodeling of polarized Madin-Darby canine kidney (MDCK) epithelial cells that undergo partial epithelial-to-mesenchymal transition (EMT) in response to hepatocyte growth factor (HGF). Results We find that HGF treatment increases MT growth rate before morphological changes are evident, and that large numbers of MTs grow into HGF-induced cell extensions independent of centrosome reorientation. Using lentivirus-mediated shRNA, we demonstrate that EB1, an adaptor protein that mediates recruitment of numerous other +TIP proteins to growing MT plus ends, is required for this HGF-induced MT reorganization. We further show that protrusion and adhesion dynamics are disorganized, and that vesicular trafficking to the tip of HGF-induced cell extensions is disrupted in EB1-depleted cells. Conclusions We conclude that EB1-mediated interactions with growing MTs are important to coordinate cell shape changes and directed migration into the surrounding extracellular matrix during epithelial remodeling in a physiological 3D environment. In contrast, EB1 is not required for the establishment or maintenance of apical-basal cell polarity, suggesting different functions of +TIPs and MTs in different types of cell polarity. PMID:22483942

  15. Fast implementation for fluorescence tomography based on coordinate descent with limited measurements

    NASA Astrophysics Data System (ADS)

    Xue, Zhenwen; Qin, Chenghu; Wu, Ping; Yang, Xin; Tian, Jie

    2012-03-01

    Fluorescence molecular tomography (FMT) can three-dimensionally resolve molecular activities in in vivo small animal through the reconstruction of the distribution of fluorescent probes. Due to large number of unknowns and limited measurements from the surfaces of small animals, the FMT problem is often ill-posed and ill-conditioned. Though various L2-norm regularizations can make the solution stable, they usually make the solution over-smoothed. During the early stages of tumor detection, fluorescent sources that indicate the distribution of tumors are usually small and sparse, which can be regarded as a type of a priori information. L1-norm regularizations have been incorporated to promote the sparsity of optical tomographic problems. In this paper, an efficient method with the L1-norm regularization based on coordinate descent is proposed to solve the FMT problem with extremely limited measurements. The proposed method minimizes the objective by solving a sequence of scalar minimization subproblems in multi-variable minimization. Each subproblem improves the estimate of the solution via minimizing along a determined coordinate with all other coordinates fixed. This algorithm first updates the coordinate that makes the energy decrease the most. Non-existence of matrix-vector multiplication in the iteration process makes the proposed algorithm time-efficient. To evaluate this method, we compare it to the iterated-shrinkage-based algorithm with L1-norm regularization in numerical experiments. The proposed algorithm is able to obtain satisfactory reconstruction results even when the measurements are very limited. Besides, the proposed algorithm is about two orders of magnitude faster than the iterated-shrinkage-based algorithm, which enables the proposed algorithm into practical applications.

  16. Solar radiation measurements from coordinated radiosonde flights during the 20th March 2015 solar eclipse

    NASA Astrophysics Data System (ADS)

    Harrison, R. Giles; Marlton, Graeme; Williams, Paul; Nicoll, Keri

    2016-04-01

    Solar radiation sensors can be carried on standard weather balloon packages and provide additional information about the atmosphere's vertical structure beyond the traditional thermodynamic measurements [1]. An interesting set of circumstances for such sensors occurs during a solar eclipse, which provides a rapidly changing solar radiation environment within the duration of a typical free balloon flight. Coordinating several launches of solar radiation measuring radiosondes brings a good likelihood of at least one being above any cloud during the maximum eclipse, allowing solar eclipse radiation measurements for comparison with theory. For the 20th March 2015 solar eclipse, a coordinated campaign of balloon-carried solar radiation measurements was undertaken from Reading (51.44N, 0.94W), Lerwick (60.15N, 1.13W) and Reykjavik (64.13N, 21.90W), straddling the path of the eclipse. All three balloons reached sufficient altitude at the eclipse time for eclipse-induced variations in solar radiation and solar limb darkening to be measured above cloud. Because the sensor platforms were free to swing, techniques have been evaluated to correct the measurements for their changing orientation. These approaches, which are essentially independent, give values that agree with theoretical expectations for the eclipse-induced radiation changes. [1] K.A. Nicoll and R.G. Harrison, Balloon-borne disposable radiometer Rev Sci Instrum 83, 025111 (2012) doi: 10.1063/1.3685252

  17. Predictive-model-based dynamic coordination control strategy for power-split hybrid electric bus

    NASA Astrophysics Data System (ADS)

    Zeng, Xiaohua; Yang, Nannan; Wang, Junnian; Song, Dafeng; Zhang, Nong; Shang, Mingli; Liu, Jianxin

    2015-08-01

    Parameter-matching methods and optimal control strategies of the top-selling hybrid electric vehicle (HEV), namely, power-split HEV, are widely studied. In particular, extant research on control strategy focuses on the steady-state energy management strategy to obtain better fuel economy. However, given that multi-power sources are highly coupled in power-split HEVs and influence one another during mode shifting, conducting research on dynamic coordination control strategy (DCCS) to achieve riding comfort is also important. This paper proposes a predictive-model-based DCCS. First, the dynamic model of the objective power-split HEV is built and the mode shifting process is analyzed based on the developed model to determine the reason for the system shock generated. Engine torque estimation algorithm is then designed according to the principle of the nonlinear observer, and the prediction model of the degree of shock is established based on the theory of model predictive control. Finally, the DCCS with adaptation for a complex driving cycle is realized by combining the feedback control and the predictive model. The presented DCCS is validated on the co-simulation platform of AMESim and Simulink. Results show that the shock during mode shifting is well controlled, thereby improving riding comfort.

  18. Integrated calibration sphere and calibration step fixture for improved coordinate measurement machine calibration

    DOEpatents

    Clifford, Harry J.

    2011-03-22

    A method and apparatus for mounting a calibration sphere to a calibration fixture for Coordinate Measurement Machine (CMM) calibration and qualification is described, decreasing the time required for such qualification, thus allowing the CMM to be used more productively. A number of embodiments are disclosed that allow for new and retrofit manufacture to perform as integrated calibration sphere and calibration fixture devices. This invention renders unnecessary the removal of a calibration sphere prior to CMM measurement of calibration features on calibration fixtures, thereby greatly reducing the time spent qualifying a CMM.

  19. Error correction of the DEA (Digital Electronic Automation) Coordinate Measuring Machines at LLNL

    SciTech Connect

    Carter, D.L.

    1989-11-14

    LLNL uses Coordinate Measuring Machines (CMM) manufactured by Digital Electronic Automation, Inc. (DEA) to provide in-process and final measurements of various components as they are assembled and aligned for later experimentation. The machines achieve their accuracy by using real-time passive error compensation to correct for all 21 parametric error components. LLNL does its own parametric testing and downloading of error correction data into the CMM's computer. This paper describes the theory, the parametric tests, the data or map,'' and the final checkout of the machines. 4 refs., 20 figs., 3 tabs.

  20. Changes in measured vector magnetic fields when transformed into heliographic coordinates

    NASA Technical Reports Server (NTRS)

    Hagyard, M. J.

    1987-01-01

    The changes that occur in measured magnetic fields when they are transformed into a heliographic coordinate system are investigated. To carry out this investigation, measurements of the vector magnetic field of an active region that was observed at 1/3 the solar radius from disk center are taken, and the observed field is transformed into heliographic coordinates. Differences in the calculated potential field that occur when the heliographic normal component of the field is used as the boundary condition rather than the observed line-of-sight component are also examined. The results of this analysis show: (1) that the observed fields of sunspots more closely resemble the generally accepted picture of the distribution of umbral fields if they are displayed in heliographic coordinates; (2) that the differences in the potential calculations are less than 200 G in field strength and 20 deg in field azimuth outside sunspots; and (3) that differences in the two potential calculations in the sunspot areas are no more than 400 G in field strength but range from 60 to 80 deg in field azimuth in localized umbral areas.

  1. Interferometer for measuring dynamic corneal topography

    NASA Astrophysics Data System (ADS)

    Micali, Jason Daniel

    The cornea is the anterior most surface of the eye and plays a critical role in vision. A thin fluid layer, the tear film, coats the outer surface of the cornea and serves to protect, nourish, and lubricate the cornea. At the same time, the tear film is responsible for creating a smooth continuous surface where the majority of refraction takes place in the eye. A significant component of vision quality is determined by the shape of the cornea and stability of the tear film. It is desirable to possess an instrument that can measure the corneal shape and tear film surface with the same accuracy and resolution that is currently performed on common optical elements. A dual interferometer system for measuring the dynamic corneal topography is designed, built, and verified. The completed system is validated by testing on human subjects. The system consists of two co-aligned polarization splitting Twyman-Green interferometers designed to measure phase instantaneously. The primary interferometer measures the surface of the tear film while the secondary interferometer simultaneously tracks the absolute position of the cornea. Eye motion, ocular variation, and a dynamic tear film surface will result in a non-null configuration of the surface with respect to the interferometer system. A non-null test results in significant interferometer induced errors that add to the measured phase. New algorithms are developed to recover the absolute surface topography of the tear film and corneal surface from the simultaneous interferometer measurements. The results are high-resolution and high-accuracy surface topography measurements of the in vivo cornea that are captured at standard camera frame rates. This dissertation will cover the development and construction of an interferometer system for measuring the dynamic corneal topography of the human eye. The discussion starts with the completion of an interferometer for measuring the tear film. The tear film interferometer is part of an

  2. Lattice gas dynamics under continuous measurement

    NASA Astrophysics Data System (ADS)

    Patil, Yogesh Sharad; Cheung, Hil F. H.; Madjarov, Ivaylo S.; Chen, Huiyao Y.; Vengalattore, Mukund

    2016-05-01

    The act of measurement has a profound consequences quantum systems. While this backaction has so far been discussed as being a limitation on the precision of measurements, it is increasingly being appreciated that measurement backaction is a powerful and versatile means of quantum control. We have previously demonstrated that backaction from position measurement can modify the coherent tunneling rate of a lattice gas through the Quantum Zeno effect. Here, we show how spatially designed measurement landscapes can be used to realize entropy segregation in lattice gases. This presents an alternate path to the longstanding challenge of realizing lattice gases with sufficiently low entropy to access regimes of correlated quantum behavior such as Néel ordered states. This work is supported by the ARO MURI on non-equilibrium dynamics.

  3. Dynamic Electrochemical Measurement of Chloride Ions.

    PubMed

    Abbas, Yawar; de Graaf, Derk B; Olthuis, Wouter; van den Berg, Albert

    2016-02-05

    This protocol describes the dynamic measurement of chloride ions using the transition time of a silver silver chloride (Ag/AgCl) electrode. Silver silver chloride electrode is used extensively for potentiometric measurement of chloride ions concentration in electrolyte. In this measurement, long-term and continuous monitoring is limited due to the inherent drift and the requirement of a stable reference electrode. We utilized the chronopotentiometric approach to minimize drift and avoid the use of a conventional reference electrode. A galvanostatic pulse is applied to an Ag/AgCl electrode which initiates a faradic reaction depleting the Cl- ions near the electrode surface. The transition time, which is the time to completely deplete the ions near the electrode surface, is a function of the ion concentration, given by the Nernst equation. The square root of the transition time is in linear relation to the chloride ion concentration. Drift of the response over two weeks is negligible (59 µM/day) when measuring 1 mM [Cl-]using a current pulse of 10 Am(-2). This is a dynamic measurement where the moment of transition time determines the response and thus is independent of the absolute potential. Any metal wire can be used as a pseudo-reference electrode, making this approach feasible for long-term measurement inside concrete structures.

  4. Dynamic Electrochemical Measurement of Chloride Ions.

    PubMed

    Abbas, Yawar; de Graaf, Derk B; Olthuis, Wouter; van den Berg, Albert

    2016-01-01

    This protocol describes the dynamic measurement of chloride ions using the transition time of a silver silver chloride (Ag/AgCl) electrode. Silver silver chloride electrode is used extensively for potentiometric measurement of chloride ions concentration in electrolyte. In this measurement, long-term and continuous monitoring is limited due to the inherent drift and the requirement of a stable reference electrode. We utilized the chronopotentiometric approach to minimize drift and avoid the use of a conventional reference electrode. A galvanostatic pulse is applied to an Ag/AgCl electrode which initiates a faradic reaction depleting the Cl- ions near the electrode surface. The transition time, which is the time to completely deplete the ions near the electrode surface, is a function of the ion concentration, given by the Nernst equation. The square root of the transition time is in linear relation to the chloride ion concentration. Drift of the response over two weeks is negligible (59 µM/day) when measuring 1 mM [Cl-]using a current pulse of 10 Am(-2). This is a dynamic measurement where the moment of transition time determines the response and thus is independent of the absolute potential. Any metal wire can be used as a pseudo-reference electrode, making this approach feasible for long-term measurement inside concrete structures. PMID:26889572

  5. The importance of measuring dynamic visual acuity.

    PubMed

    Muzdalo, Natasa Vujko

    2013-04-01

    In their everyday life, people interact with different objects, static as well as those in motion. However, dynamic acuity is rarely checked in medical examinations, even those preceding the issue of driving license. In order for driving to be safe, good eyesight or good correction with visual aids is imperative. Beside good eyesight, drivers also have to have good reflexes and short reaction span. The aim of this study was to compare dynamic and static visual acuity in order to observe how they vary among individuals. Twenty female and male participants, 65 years of age, took part in the study and the comparison was made with the results provided by 20 20-year old participants. Dynamic acuity was tested using the Landolt-ring optotype which was simulating movement velocity of 72 km/h. T-test demonstrated the presence of a statistically significant difference between dynamic and static acuity among the participants from 62 to 68 years of age (t = 15.852; df = 39; p < 0.01). Within the same group, dynamic acuity (mean = 0.887; std. deviation = 0.297) proved to be significantly worse than static acuity (mean = 1.40; std. deviation = 0.317). By comparing the results measured within the older group of participants with those measured in the younger group, it was shown that there exists a statistically significant difference (t = 0.275; df = 58; p < 0,05) between the older and younger group in their dynamic binocular acuity with correction. Younger participants had better dynamic binocular acuity with correction (mean = 1.063; std. deviation = 0.259) than the older participants (mean = 0.884; std. deviation = 0.298). The differences between dynamic and static acuity and its degradation in the older age groups have to be taken into account when issuing driving licenses. The future of research lies within the study of correlation between the age and acuity in order that the results can be applied in practice.

  6. Biological oscillations for learning walking coordination: dynamic recurrent neural network functionally models physiological central pattern generator.

    PubMed

    Hoellinger, Thomas; Petieau, Mathieu; Duvinage, Matthieu; Castermans, Thierry; Seetharaman, Karthik; Cebolla, Ana-Maria; Bengoetxea, Ana; Ivanenko, Yuri; Dan, Bernard; Cheron, Guy

    2013-01-01

    The existence of dedicated neuronal modules such as those organized in the cerebral cortex, thalamus, basal ganglia, cerebellum, or spinal cord raises the question of how these functional modules are coordinated for appropriate motor behavior. Study of human locomotion offers an interesting field for addressing this central question. The coordination of the elevation of the 3 leg segments under a planar covariation rule (Borghese et al., 1996) was recently modeled (Barliya et al., 2009) by phase-adjusted simple oscillators shedding new light on the understanding of the central pattern generator (CPG) processing relevant oscillation signals. We describe the use of a dynamic recurrent neural network (DRNN) mimicking the natural oscillatory behavior of human locomotion for reproducing the planar covariation rule in both legs at different walking speeds. Neural network learning was based on sinusoid signals integrating frequency and amplitude features of the first three harmonics of the sagittal elevation angles of the thigh, shank, and foot of each lower limb. We verified the biological plausibility of the neural networks. Best results were obtained with oscillations extracted from the first three harmonics in comparison to oscillations outside the harmonic frequency peaks. Physiological replication steadily increased with the number of neuronal units from 1 to 80, where similarity index reached 0.99. Analysis of synaptic weighting showed that the proportion of inhibitory connections consistently increased with the number of neuronal units in the DRNN. This emerging property in the artificial neural networks resonates with recent advances in neurophysiology of inhibitory neurons that are involved in central nervous system oscillatory activities. The main message of this study is that this type of DRNN may offer a useful model of physiological central pattern generator for gaining insights in basic research and developing clinical applications.

  7. Accuracy and versatility of the NIST M48 coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Stoup, John R.; Doiron, Theodore D.

    2001-10-01

    The NIST Is continuing to develop the ability to perform accurate, traceable measurements on a wide range of artifacts using a very precise, error-mapped coordinate measuring machine (CMM). The NIST M48 CMM has promised accuracy and versatility for many ears. Recently, these promises have been realized in a reliable, reproducible way for many types of 1D, 2D, and 3D engineering metrology artifacts. The versatility of the machine has permitted state-of-the-art, accurate measurements of one meter step gages and precision ball plates as well as 500 micrometer holes and small precision parts made of aluminum or glass. To accomplish this wide range of measurements the CMM has required extensive assessment of machine positioning and straightness errors, probe response, machine motion control and speed, environmental stability, and measurement procedures. The CMM has been used as an absolute instrument and as a very complicated comparator. The data collection techniques have been designed to acquire statistical information on the machine and probe performance and to evaluate and remove any potential thermal drift in the machine coordinate system during operation. This paper will present the data collection and measurement techniques used by NIST to achieve excellent measurement results for gage blocks, long end standards, step gages, ring and plug gages, small holes, ball plates, and angular artifacts. Comparison data with existing independent primary measuring instruments will also be presented to show agreement and correlation with those historical methods. Current plans for incorporating the CMM into existing measurement services, such as plain ring gages, large plug gages, and long end standards, will be presented along with other proposed development of this CMM.

  8. Partially implicit finite difference scheme for calculating dynamic pressure in a terrain-following coordinate non-hydrostatic ocean model

    NASA Astrophysics Data System (ADS)

    Liu, Zhe; Lin, Lei; Xie, Lian; Gao, Huiwang

    2016-10-01

    To improve the efficiency of the terrain-following σ-coordinate non-hydrostatic ocean model, a partially implicit finite difference (PIFD) scheme is proposed. By using explicit terms instead of implicit terms to discretize the parts of the vertical dynamic pressure gradient derived from the σ-coordinate transformation, the coefficient matrix of the discrete Poisson equation that the dynamic pressure satisfies can be simplified from 15 diagonals to 7 diagonals. The PIFD scheme is shown to run stably when it is applied to simulate five benchmark cases, namely, a standing wave in a basin, a surface solitary wave, a lock-exchange problem, a periodic wave over a bar and a tidally induced internal wave. Compared with the conventional fully implicit finite difference (FIFD) scheme, the PIFD scheme produces simulation results of equivalent accuracy at only 40-60% of the computational cost. The PIFD scheme demonstrates strong applicability and can be easily implemented in σ-coordinate ocean models.

  9. Viscosity measurement techniques in Dissipative Particle Dynamics

    NASA Astrophysics Data System (ADS)

    Boromand, Arman; Jamali, Safa; Maia, Joao M.

    2015-11-01

    In this study two main groups of viscosity measurement techniques are used to measure the viscosity of a simple fluid using Dissipative Particle Dynamics, DPD. In the first method, a microscopic definition of the pressure tensor is used in equilibrium and out of equilibrium to measure the zero-shear viscosity and shear viscosity, respectively. In the second method, a periodic Poiseuille flow and start-up transient shear flow is used and the shear viscosity is obtained from the velocity profiles by a numerical fitting procedure. Using the standard Lees-Edward boundary condition for DPD will result in incorrect velocity profiles at high values of the dissipative parameter. Although this issue was partially addressed in Chatterjee (2007), in this work we present further modifications (Lagrangian approach) to the original LE boundary condition (Eulerian approach) that will fix the deviation from the desired shear rate at high values of the dissipative parameter and decrease the noise to signal ratios in stress measurement while increases the accessible low shear rate window. Also, the thermostat effect of the dissipative and random forces is coupled to the dynamic response of the system and affects the transport properties like the viscosity and diffusion coefficient. We investigated thoroughly the dependency of viscosity measured by both Eulerian and Lagrangian methodologies, as well as numerical fitting procedures and found that all the methods are in quantitative agreement.

  10. The study of dual camera 3D coordinate vision measurement system using a special probe

    NASA Astrophysics Data System (ADS)

    Liu, Shugui; Peng, Kai; Zhang, Xuefei; Zhang, Haifeng; Huang, Fengshan

    2006-11-01

    Due to high precision and convenient operation, the vision coordinate measurement machine with one probe has become the research focus in visual industry. In general such a visual system can be setup conveniently with just one CCD camera and probe. However, the price of the system will surge up too high to accept while the top performance hardware, such as CCD camera, image captured card and etc, have to be applied in the system to obtain the high axis-oriented measurement precision. In this paper, a new dual CCD camera vision coordinate measurement system based on redundancy principle is proposed to achieve high precision by moderate price. Since two CCD cameras are placed with the angle of camera axis like about 90 degrees to build the system, two sub-systems can be built by each CCD camera and the probe. With the help of the probe the inner and outer parameters of camera are first calibrated, the system by use of redundancy technique is set up now. When axis-oriented error is eliminated within the two sub-systems, which is so large and always exits in the single camera system, the high precision measurement is obtained by the system. The result of experiment compared to that from CMM shows that the system proposed is more excellent in stableness and precision with the uncertainty beyond +/-0.1 mm in xyz orient within the distance of 2m using two common CCD cameras.

  11. Mars 2001 Lander Mission: Measurement Synergy Through Coordinated Operations Planning And Implementation

    NASA Technical Reports Server (NTRS)

    Arvidson, R.; Bell, J. F., III; Kaplan, D.; Marshall, J.; Mishkin, A.; Saunders, S.; Smith, P.; Squyres, S.

    1999-01-01

    , together with quantitative information on material mineralogy, chemistry, and physical properties (rock textures; soil grain size and shape distributions; degree and nature of soil induration; soil magnetic properties). The calibration targets provide radiometric and mineralogical control surfaces. The magnets allow observations of magnetic phases. Patch plates are imaged to determine adhesive and abrasive properties of soils. Coordinated mission planning is crucial for optimizing the measurement synergy among the packages included on the lander. This planning has already begun through generation of multi-sol detailed operations activities. One focus has been to develop a scenario to use the arm to dig a soil trench to a depth of tens of centimeters. The activity will be monitored through use of Pancam and RAC to ensure nominal operations and to acquire data to determine subsurface physical properties (e.g., angle of repose of trench walls). Pancam and Mini-TES observations would also provide constraints on mineralogy and texture for the walls and bottom of the trench during excavation. If desired, soils excavated at depth could be deposited on the surface and Mossbauer and APXS measurements could be acquired for these materials. Soil samples from various depths would be delivered to MECA for characterization of aqueous geochemistry and physical properties of soil grains, particularly size, shape, and hardness. These physical properties would be determined by optical and atomic force microscopy. When completed, detailed information of soil properties as a function of depth would be obtained. These various data sets would constrain our understanding of whether or not there are systematic variations in soil characteristics as a function of depth. These variations might be related, for example, to evaporative moisture losses and formation of salt deposits, thereby indicating water transport processes occurred fairly recently. Many other value-added measurement scenarios are

  12. Optical dynamic deformation measurements at translucent materials.

    PubMed

    Philipp, Katrin; Koukourakis, Nektarios; Kuschmierz, Robert; Leithold, Christoph; Fischer, Andreas; Czarske, Jürgen

    2015-02-15

    Due to their high stiffness-to-weight ratio, glass fiber-reinforced polymers are an attractive material for rotors, e.g., in the aerospace industry. A fundamental understanding of the material behavior requires non-contact, in-situ dynamic deformation measurements. The high surface speeds and particularly the translucence of the material limit the usability of conventional optical measurement techniques. We demonstrate that the laser Doppler distance sensor provides a powerful and reliable tool for monitoring radial expansion at fast rotating translucent materials. We find that backscattering in material volume does not lead to secondary signals as surface scattering results in degradation of the measurement volume inside the translucent medium. This ensures that the acquired signal contains information of the rotor surface only, as long as the sample surface is rough enough. Dynamic deformation measurements of fast-rotating fiber-reinforced polymer composite rotors with surface speeds of more than 300 m/s underline the potential of the laser Doppler sensor.

  13. Multidimensional characterization of stochastic dynamical systems based on multiple perturbations and measurements

    SciTech Connect

    Kryvohuz, Maksym Mukamel, Shaul

    2015-06-07

    Generalized nonlinear response theory is presented for stochastic dynamical systems. Experiments in which multiple measurements of dynamical quantities are used along with multiple perturbations of parameters of dynamical systems are described by generalized response functions (GRFs). These constitute a new type of multidimensional measures of stochastic dynamics either in the time or the frequency domains. Closed expressions for GRFs in stochastic dynamical systems are derived and compared with numerical non-equilibrium simulations. Several types of perturbations are considered: impulsive and periodic perturbations of temperature and impulsive perturbations of coordinates. The present approach can be used to study various types of stochastic processes ranging from single-molecule conformational dynamics to chemical kinetics of finite-size reactors such as biocells.

  14. Installation and Implementation of an In-Process Coordinate Measuring Machine (CMM)

    SciTech Connect

    Johnston, Derek

    2008-06-16

    This report documents the work accomplished during the installation and implementation of the in-process Coordinate Measuring Machine (CMM) in Department A. A wealth of knowledge has been gained in solving the many technical issues that delayed the partial implementation of this CMM. The work completed thus far lead to the successfully calibrated in-process CMM workstation. A great deal of current and future work has been outlined in the following pages that shall be used as a guide for the full implementation of this CMM with machining processes in Department A.

  15. A new concept of feature-based gauge for coordinate measuring arm evaluation

    NASA Astrophysics Data System (ADS)

    Cuesta, E.; González-Madruga, D.; Alvarez, B. J.; Barreiro, J.

    2014-06-01

    Articulated arm coordinate measuring machines (AACMM or CMA) have conquered a market share in the actual dimensional metrology field, overall when their role implies the inspection of geometrical and dimensional tolerances in an accurate 3D environment for medium-size parts. However, the unavoidable fact of AACMM manual operation constrains its reliability to a great extent, avoiding rigorous evaluation and casting doubt upon the usefulness of external calibration. In this research, a dimensional gauge especially aimed at AACMM evaluation has been developed. Furthermore, the operator skill will be revealed through the use of this gauge. A set of geometrical features, some of them oriented to evaluate the operator and others the equipment, have been collected for the gauge. The proposed evaluation methodology clearly distinguishes between dimensional and geometrical tolerances (with or without datum references), whereas actual verification standards only consider the former. Next, quality indicators deduced from the measurement results are proposed in order to compare AACMM versus coordinate measuring machine (CMM) performance, assuming that CMM possess the maximum accuracy that AACMM could reach, because CMM combines maximum contact accuracy with minimum operator influence. As a result, AACMM evaluation time could be significantly reduced since this gauge allows us to perform a customized evaluation of only those specific tolerances of interest to the user.

  16. Testing coordinate measuring arms with a geometric feature-based gauge: in situ field trials

    NASA Astrophysics Data System (ADS)

    Cuesta, E.; Alvarez, B. J.; Patiño, H.; Telenti, A.; Barreiro, J.

    2016-05-01

    This work describes in detail the definition of a procedure for calibrating and evaluating coordinate measuring arms (AACMMs or CMAs). CMAs are portable coordinate measuring machines that have been widely accepted in industry despite their sensitivity to the skill and experience of the operator in charge of the inspection task. The procedure proposed here is based on the use of a dimensional gauge that incorporates multiple geometric features, specifically designed for evaluating the measuring technique when CMAs are used, at company facilities (workshops or laboratories) and by the usual operators who handle these devices in their daily work. After establishing the procedure and manufacturing the feature-based gauge, the research project was complemented with diverse in situ field tests performed with the collaboration of companies that use these devices in their inspection tasks. Some of the results are presented here, not only comparing different operators but also comparing different companies. The knowledge extracted from these experiments has allowed the procedure to be validated, the defects of the methodologies currently used for in situ inspections to be detected, and substantial improvements for increasing the reliability of these portable instruments to be proposed.

  17. The ANGWIN Antarctic Research Program: First Results on Coordinated Trans-Antarctic Gravity Wave Measurements

    NASA Astrophysics Data System (ADS)

    Taylor, M. J.; Pautet, P. D.; Zhao, Y.; Nakamura, T.; Ejiri, M. K.; Murphy, D. J.; Moffat-Griffin, T.; Kavanagh, A. J.; Takahashi, H.; Wrasse, C. M.

    2014-12-01

    ANGWIN (ANrctic Gravity Wave Instrument Network) is a new "scientist driven" research program designed to develop and utilize a network of Antarctic atmospheric gravity wave observatories, operated by different nations working together in a spirit of close scientific collaboration. Our research plan has brought together colleagues from several international institutions, all with a common goal to better understand the large "continental-scale" characteristics and impacts of gravity waves on the Mesosphere and Lower Thermosphere (MLT) environment over Antarctica. ANGWIN combines complementary measurements obtained using new and existing aeronomy instrumentation with new modeling capabilities. To date, our activities have focused on developing coordinated airglow image data of gravity waves in the MLT region at the following sites: McMurdo (US), Syowa (Japan), Davis (Australia), Halley (UK), Rothera (UK), and Comandante Ferraz (Brazil). These are all well-established international research stations that are uniformly distributed around the continental perimeter, and together with ongoing measurements at South Pole Station they provide unprecedented coverage of the Antarctic gravity wave field and its variability during the extended polar winter season. This presentation introduces the ANGWIN program and research goals, and presents first results on trans-Antarctic wave propagation using coordinated measurements during the winter season 2011. We also discuss future plans for the development of this exciting program for Antarctic research.

  18. The light pen of a no guide 3D-coordinate measuring system

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaofang; Jiang, Chengzhi; Xue, Tongze; Li, Cuiying; Wang, Biru

    2006-11-01

    With the advantages of simple structure, high speed, and high accuracy, a no guide 3D-coordinate measuring technique that using the photoelectric detectors with intersection converge imaging has the predominance in workshop measurement. Its measuring head is made in a pen shape with several light sources, which is called as the light pen. In this paper, the structure design and self-calibration of light pen system are analyzed, and the identifying way for multi-sources on light pen is present. The Laser-balls are offered to be the light-sources while the principles as well as fabrication are introduced. The light pen can insert and touch the points of inner surface in a deep hole. So the localization of CMM can be avoided by using the light pen with simple and deft structure.

  19. Evolving dynamics of trading behavior based on coordination game in complex networks

    NASA Astrophysics Data System (ADS)

    Bian, Yue-tang; Xu, Lu; Li, Jin-sheng

    2016-05-01

    This work concerns the modeling of evolvement of trading behavior in stock markets. Based on the assumption of the investors' limited rationality, the evolution mechanism of trading behavior is modeled according to the investment strategy of coordination game in network, that investors are prone to imitate their neighbors' activity through comprehensive analysis on the risk dominance degree of certain investment behavior, the network topology of their relationship and its heterogeneity. We investigate by mean-field analysis and extensive simulations the evolution of investors' trading behavior in various typical networks under different risk dominance degree of investment behavior. Our results indicate that the evolution of investors' behavior is affected by the network structure of stock market and the effect of risk dominance degree of investment behavior; the stability of equilibrium states of investors' behavior dynamics is directly related with the risk dominance degree of some behavior; connectivity and heterogeneity of the network plays an important role in the evolution of the investment behavior in stock market.

  20. Coordinating Multi-Rover Systems: Evaluation Functions for Dynamic and Noisy Environments

    NASA Technical Reports Server (NTRS)

    Turner, Kagan; Agogino, Adrian

    2005-01-01

    This paper addresses the evolution of control strategies for a collective: a set of entities that collectively strives to maximize a global evaluation function that rates the performance of the full system. Directly addressing such problems by having a population of collectives and applying the evolutionary algorithm to that population is appealing, but the search space is prohibitively large in most cases. Instead, we focus on evolving control policies for each member of the collective. The fundamental issue in this approach is how to create an evaluation function for each member of the collective that is both aligned with the global evaluation function and is sensitive to the fitness changes of the member, while relatively insensitive to the fitness changes of other members. We show how to construct evaluation functions in dynamic, noisy and communication-limited collective environments. On a rover coordination problem, a control policy evolved using aligned and member-sensitive evaluations outperfoms global evaluation methods by up to 400%. More notably, in the presence of a larger number of rovers or rovers with noisy and communication limited sensors, the proposed method outperforms global evaluation by a higher percentage than in noise-free conditions with a small number of rovers.

  1. Embodied economics: how bodily information shapes the social coordination dynamics of decision-making.

    PubMed

    Oullier, Olivier; Basso, Frédéric

    2010-01-27

    To date, experiments in economics are restricted to situations in which individuals are not influenced by the physical presence of other people. In such contexts, interactions remain at an abstract level, agents guessing what another person is thinking or is about to decide based on money exchange. Physical presence and bodily signals are therefore left out of the picture. However, in real life, social interactions (involving economic decisions or not) are not solely determined by a person's inference about someone else's state-of-mind. In this essay, we argue for embodied economics: an approach to neuroeconomics that takes into account how information provided by the entire body and its coordination dynamics influences the way we make economic decisions. Considering the role of embodiment in economics--movements, posture, sensitivity to mimicry and every kind of information the body conveys--makes sense. This is what we claim in this essay which, to some extent, constitutes a plea to consider bodily interactions between agents in social (neuro)economics.

  2. Embodied economics: how bodily information shapes the social coordination dynamics of decision-making

    PubMed Central

    Oullier, Olivier; Basso, Frédéric

    2010-01-01

    To date, experiments in economics are restricted to situations in which individuals are not influenced by the physical presence of other people. In such contexts, interactions remain at an abstract level, agents guessing what another person is thinking or is about to decide based on money exchange. Physical presence and bodily signals are therefore left out of the picture. However, in real life, social interactions (involving economic decisions or not) are not solely determined by a person's inference about someone else's state-of-mind. In this essay, we argue for embodied economics: an approach to neuroeconomics that takes into account how information provided by the entire body and its coordination dynamics influences the way we make economic decisions. Considering the role of embodiment in economics—movements, posture, sensitivity to mimicry and every kind of information the body conveys—makes sense. This is what we claim in this essay which, to some extent, constitutes a plea to consider bodily interactions between agents in social (neuro)economics. PMID:20026467

  3. Strength and weaknesses of modeling the dynamics of mode-locked lasers by means of collective coordinates

    NASA Astrophysics Data System (ADS)

    Alsaleh, M.; Mback, C. B. L.; Tchomgo Felenou, E.; Tchofo Dinda, P.; Grelu, Ph; Porsezian, K.

    2016-07-01

    We address the efficiency of theoretical tools used in the development and optimization of mode-locked fiber lasers. Our discussion is based on the practical case of modeling the dynamics of a dispersion-managed fiber laser. One conventional approach uses discrete propagation equations, followed by the analysis of the numerical results through a collective coordinate projection. We compare the latter with our dynamical collective coordinate approach (DCCA), which combines both modeling and analysis in a compact form. We show that for single pulse dynamics, the DCCA allows a much quicker solution mapping in the space of cavity parameters than the conventional approach, along with a good accuracy. We also discuss the weaknesses of the DCCA, in particular when multiple pulsing bifurcations occur.

  4. Bio-inspired metal-coordination dynamics: A unique tool for engineering novel properties in soft matter systems

    NASA Astrophysics Data System (ADS)

    Grindy, Scott; Li, Qiaochu; Halim, Abigail; Learsch, Robert; Holten-Andersen, Niels

    2015-03-01

    In soft material systems, materials properties are generally governed by transient, dynamic interactions of many types over many hierarchal length- and time-scales. However, explicit control over these dynamics is not always possible, leaving open questions into how transient interactions can be exploited to design soft materials with unique and exceptional properties. Inspired by the adhesive chemistry and tough character of mussel byssal threads, we present several studies on both the mechanical properties of soft materials and templated crystallization kinetics to show the diverse array of materials properties that can be generated using bio-inspired metal-coordination. By studying our model systems, we can determine the explicit effects of metal-coordination dynamics on various bulk properties, further adding to the set of tools we can use to design soft material systems.

  5. Measurement of Gear Tooth Dynamic Friction

    NASA Technical Reports Server (NTRS)

    Rebbechi, Brian; Oswald, Fred B.; Townsend, Dennis P.

    1996-01-01

    Measurements of dynamic friction forces at the gear tooth contact were undertaken using strain gages at the root fillets of two successive teeth. Results are presented from two gear sets over a range of speeds and loads. The results demonstrate that the friction coefficient does not appear to be significantly influenced by the sliding reversal at the pitch point, and that the friction coefficient values found are in accord with those in general use. The friction coefficient was found to increase at low sliding speeds. This agrees with the results of disc machine testing.

  6. HotEye (tm) Based Coordinate Measuring Machine for Forging Industry

    SciTech Connect

    OG Technologies

    2003-06-09

    The objective of this project is to develop a 3 dimensional measurement system for the domestic forging industry based on HotEye{trademark}. This technology will allow high definition camera to accurately image a red hot object. The project marries conventional Coordinate Measurement Machine ''CMM'' technology to HotEye{trademark} technology to permit the accurate measurement of forged parts while they are at high temperature. Being able to take such measurements will dramatically reduce the amount of scrap produced by the domestic forging industry. This industry wastes a significant amount of energy because of the high rate of scrap it produces. OGT will: (1) Develop a 3D measurement sensor head that will work on a part at a temperature up to 1,450 C with an accuracy of 0.1mm or better and with a scanning speed of less than 10 seconds for an area of 100mm x 100mm. (2) Develop a Virtual-Fixturing software package to alleviate the need of precise hard fixturing. (3) Integrate the 3D measurement sensor head and the Virtual-Fixturing software into a standard CMM, both hardware (replacing the probes) and software (data format and user interface match) so that the system can automatically perform a complete preprogrammed measurement of a hot product. (4) Test and evaluate the system in a forging facility.

  7. Atomic Quadrupole Moment Measurement Using Dynamic Decoupling.

    PubMed

    Shaniv, R; Akerman, N; Ozeri, R

    2016-04-01

    We present a method that uses dynamic decoupling of a multilevel quantum probe to distinguish small frequency shifts that depend on m_{j}^{2}, where m_{j}^{2} is the angular momentum of level |j⟩ along the quantization axis, from large noisy shifts that are linear in m_{j}, such as those due to magnetic field noise. Using this method we measured the electric-quadrupole moment of the 4D_{5/2} level in ^{88}Sr^{+} to be 2.973_{-0.033}^{+0.026}ea_{0}^{2}. Our measurement improves the uncertainty of this value by an order of magnitude and thus helps mitigate an important systematic uncertainty in ^{88}Sr^{+} based optical atomic clocks and verifies complicated many-body quantum calculations.

  8. Atomic Quadrupole Moment Measurement Using Dynamic Decoupling.

    PubMed

    Shaniv, R; Akerman, N; Ozeri, R

    2016-04-01

    We present a method that uses dynamic decoupling of a multilevel quantum probe to distinguish small frequency shifts that depend on m_{j}^{2}, where m_{j}^{2} is the angular momentum of level |j⟩ along the quantization axis, from large noisy shifts that are linear in m_{j}, such as those due to magnetic field noise. Using this method we measured the electric-quadrupole moment of the 4D_{5/2} level in ^{88}Sr^{+} to be 2.973_{-0.033}^{+0.026}ea_{0}^{2}. Our measurement improves the uncertainty of this value by an order of magnitude and thus helps mitigate an important systematic uncertainty in ^{88}Sr^{+} based optical atomic clocks and verifies complicated many-body quantum calculations. PMID:27104691

  9. Coordinated measurements of low-energy electron precipitation and scintilations/TEC in the auroral oval

    SciTech Connect

    Basu, S.; Mackenzie, E.; Basu, S.

    1983-11-01

    A geostationary satellite transmitting at 244 MHz was employed in a coordinated observation study of low energy electron precipitation in the auroral oval from DMSP/F2 (a satellite in sun-synchronous circular orbit) and phase and amplitude scintillations from Goose Bay, Labrador. Total electron content and magnetometer measurements indicate that the precipitation event onset was 10 min prior to the DMSP pass. Within this time scale, the ionization generated in the F region could reach the topside, so that the thermal sensor on board the DMSP satellite could measure a factor of 2-3 density enhancement. The phase-to-amplitude ratio changed drastically by comparison to quiet magnetic times, implying that increased convection velocities during magnetic disturbances were partially responsible for the enhanced phase scintillation. 49 references.

  10. Dimensionality and Size Scaling of Coordinated Ca2+ Dynamics in MIN6 β-cell Clusters

    PubMed Central

    Hraha, Thomas H.; Bernard, Abigail B.; Nguyen, Linda M.; Anseth, Kristi S.; Benninger, Richard K.P.

    2014-01-01

    Pancreatic islets of Langerhans regulate blood glucose homeostasis by the secretion of the hormone insulin. Like many neuroendocrine cells, the coupling between insulin-secreting β-cells in the islet is critical for the dynamics of hormone secretion. We have examined how this coupling architecture regulates the electrical dynamics that underlie insulin secretion by utilizing a microwell-based aggregation method to generate clusters of a β-cell line with defined sizes and dimensions. We measured the dynamics of free-calcium activity ([Ca2+]i) and insulin secretion and compared these measurements with a percolating network model. We observed that the coupling dimension was critical for regulating [Ca2+]i dynamics and insulin secretion. Three-dimensional coupling led to size-invariant suppression of [Ca2+]i at low glucose and robust synchronized [Ca2+]i oscillations at elevated glucose, whereas two-dimensional coupling showed poor suppression and less robust synchronization, with significant size-dependence. The dimension- and size-scaling of [Ca2+]i at high and low glucose could be accurately described with the percolating network model, using similar network connectivity. As such this could explain the fundamentally different behavior and size-scaling observed under each coupling dimension. This study highlights the dependence of proper β-cell function on the coupling architecture that will be important for developing therapeutic treatments for diabetes such as islet transplantation techniques. Furthermore, this will be vital to gain a better understanding of the general features by which cellular interactions regulate coupled multicellular systems. PMID:24411262

  11. Embodiment of intersubjective time: relational dynamics as attractors in the temporal coordination of interpersonal behaviors and experiences

    PubMed Central

    Laroche, Julien; Berardi, Anna Maria; Brangier, Eric

    2014-01-01

    This paper addresses the issue of “being together,” and more specifically the issue of “being together in time.” We provide with an integrative framework that is inspired by phenomenology, the enactive approach and dynamical systems theories. To do so, we first define embodiment as a living and lived phenomenon that emerges from agent-world coupling. We then show that embodiment is essentially dynamical and therefore we describe experiential, behavioral and brain dynamics. Both lived temporality and the temporality of the living appear to be complex, multiscale phenomena. Next we discuss embodied dynamics in the context of interpersonal interactions, and briefly review the empirical literature on between-persons temporal coordination. Overall, we propose that being together in time emerges from the relational dynamics of embodied interactions and their flexible co-regulation. PMID:25400598

  12. An Investigation of Embodied Language Comprehension from the Perspective of Coordination Dynamics

    ERIC Educational Resources Information Center

    Olmstead, Anne Jane

    2009-01-01

    In four experiments, participants performed sentence comprehension tasks simultaneously with bimanual coordination. Half of the sentences described events that could not be performed by a human (non-performable) and half described actions that could be performed by a human (performable). Effects of sentence type on coordination were indexed by…

  13. Application of a Force Sensor to Improve the Reliability of Measurement with Articulated Arm Coordinate Measuring Machines

    PubMed Central

    González-Madruga, Daniel; Eduardo Cuesta, González; Joaquín Barreiro, García; Fernandez-Abia, Ana Isabel

    2013-01-01

    A study of the operator contact force influence on the performance of Articulated Arm Coordinate Measuring Machines (AACMMs) is presented in this paper. After developing a sensor capable of measuring the contact force applied by an operator, a ring gauge has been used to analyse the relationship between the contact force and diameter and form errors measured with the AACMM. As a result, contact force has been proved as one of the main factors influencing the AACMM performance. A probe deflection model based on the Finite Element Method (FEM) has been also proposed in order to obtain the AACMM probe deflection caused by contact force. This allows measurement correction by comparing them with reference values, specifically, a ring gauge. Experimental test results show a significant measurement improvement that minimizes diameter error. Finally, an uncertainty evaluation for the contact force sensor and AACMM measurements with and without probe deflection model has been carried out in order to validate the ability of the sensor and the methodology followed. PMID:23945737

  14. Finite elements using absolute nodal coordinates for large-deformation flexible multibody dynamics

    NASA Astrophysics Data System (ADS)

    Dmitrochenko, Oleg

    2008-06-01

    A family of structural finite elements using a modern absolute nodal coordinate formulation (ANCF) is discussed in the paper with many applicationsE This approach has been initiated in 1996 by A. Shabana. It introduces large displacements of 2D/3D finite elements relative to the global reference frame without using any local frame. The elements employ finite slopes as nodal variables and can be considered as generalizations of ordinary finite elements that use infinitesimal slopes. In contrast to other large deformation formulations, the equations of motion contain constant mass matrices and generalized gravity forces as well as zero centrifugal and Coriolis inertia forces. The only nonlinear term is a vector of elastic forces. This approach allows applying known abstractions of real elastic bodies: Euler-Bernoulli beams, Timoshenko beams and more general models as well as Kirchhoff and Mindlin plate theories. Shabana et al. proposed a sub-family of thick beam and plate finite elements with large deformations and employ the 3D theory of continuum mechanics. Despite the universality of such approach it has to use extra degrees of freedom when simulating thin beams and plates, which case is most important. In our research, we propose another sub-family of thin beams as well as rectangular and triangle plates. We use Kirchhoff plate theory with nonlinear strain-displacement relationships to obtain elastic forces. A number of static and dynamic simulation examples of problems with 2D/3D very elastic beams and plate underwent large displacements and/or deformations will be shown in the presentation.

  15. Dynamic neurotransmitter interactions measured with PET

    SciTech Connect

    Schiffer, W.K.; Dewey, S.L.

    2001-04-02

    Positron emission tomography (PET) has become a valuable interdisciplinary tool for understanding physiological, biochemical and pharmacological functions at a molecular level in living humans, whether in a healthy or diseased state. The utility of tracing chemical activity through the body transcends the fields of cardiology, oncology, neurology and psychiatry. In this, PET techniques span radiochemistry and radiopharmaceutical development to instrumentation, image analysis, anatomy and modeling. PET has made substantial contributions in each of these fields by providing a,venue for mapping dynamic functions of healthy and unhealthy human anatomy. As diverse as the disciplines it bridges, PET has provided insight into an equally significant variety of psychiatric disorders. Using the unique quantitative ability of PET, researchers are now better able to non-invasively characterize normally occurring neurotransmitter interactions in the brain. With the knowledge that these interactions provide the fundamental basis for brain response, many investigators have recently focused their efforts on an examination of the communication between these chemicals in both healthy volunteers and individuals suffering from diseases classically defined as neurotransmitter specific in nature. In addition, PET can measure the biochemical dynamics of acute and sustained drug abuse. Thus, PET studies of neurotransmitter interactions enable investigators to describe a multitude of specific functional interactions in the human brain. This information can then be applied to understanding side effects that occur in response to acute and chronic drug therapy, and to designing new drugs that target multiple systems as opposed to single receptor types. Knowledge derived from PET studies can be applied to drug discovery, research and development (for review, see (Fowler et al., 1999) and (Burns et al., 1999)). Here, we will cover the most substantial contributions of PET to understanding

  16. Determination of dynamic corrections to point coordinates of photographs obtained by the Zond 6 and Zond 8 spacecraft. [image motion correction

    NASA Technical Reports Server (NTRS)

    Kiselev, V. V.; Rodionov, B. N.

    1974-01-01

    The linear and angular motions of the Zond 6 and Zond 8 spacecraft imaging camera during the exposure cause displacements of the optical image points. In the case of instantaneous exposure of each individual point and the nonsimultaneous exposure of the complete frame, this leads to finite geometric shifts of the points without causing blurring of the photographic image. Therefore, when measuring the resulting photographic pictures, the problem arises of reducing the picture point positions to a common instant of time. This reduction is performed by means of dynamic corrections to the measured picture point coordinates. These corrections are found by using formulas of dynamic photogrammetry. Their use with the Zond space probe photographs is described.

  17. External and internal waves in stream-potential pressure-coordinate dynamics

    NASA Astrophysics Data System (ADS)

    Zirk, Marko; Rõõm, Rein

    2014-05-01

    In stream-potential dynamics pressure coordinate velocity -→v = {dx/dt,dy/dt,dp/dt} = {vx,vy,vp} = {u,v,ω } is presented in terms of 4D stream-potential {ψ0,ψx,ψy,ψp} -→v = downtriangleψ0 + downtriangle× -→ψ leftrightarrow vi = Giαδαψ0 + ɛαβγδβψγ, with diagonal metric tensor with main elements G11 = G22 = 1, G33 = p2/H2 (H = RT/g is the height scale). Vector potential -→ ψ is further expressed via horizontal curl and divergence of the stream function ω = δxψy - δyψx ≠¡ dp/dt, Ξ = δxψx + δyψy. The wave-vector components in linearized stream-potential dynamics are the scalar flow potential ψ0, surface pressure fluctuation p's, horizontal divergence Ξ and curl ω of the fluctuative part -→ψ' of complete vector potential -→ψ = -→ψ + -→ψ' . Equations for ψ0 and p's form the external wave subsystem δp' δ« ps dξ0 - -→- p2 δ2 -s+ downtriangle2 ψ0dp = 0, -+gH downtriangle2(p's/ps) = A0(ψ ,ω,Ξ), L0ψ0 = ξ0, L0 =-2 -2+downtriangle2, δt 0 dt H δp (1) while the equations for Ξ, ω and temperature fluctuation T' form the internal wave subsystem d-→ξ -→ -→- dT ' Tiω ( ) ( p2 δ2 ) p2 -dt = A (ψ,ω,Ξ), -dt = -p-+Q, L0Ξ = δp p2ξp/H2 , H2- δp2 + downtriangle2 ω = H2-(δyξx - δxξy) (2) with Ti = (R/cp)T - pδpT. In these equations 0 -→ α -→ -→ i iαβ ξ = downtriangle · v = δαv , ξ = downtriangle ×v leftrightarrow ξ = ɛ δαvβ are the 3D divergence and curl of velocity. In the presentation equation systems (1) and (2) are solved both analytically and numerically. Interaction of external waves with stationary internal orographic waves is investigated.

  18. Integrative data analysis through coordination of measurement and analysis protocol across independent longitudinal studies.

    PubMed

    Hofer, Scott M; Piccinin, Andrea M

    2009-06-01

    Replication of research findings across independent longitudinal studies is essential for a cumulative and innovative developmental science. Meta-analysis of longitudinal studies is often limited by the amount of published information on particular research questions, the complexity of longitudinal designs and the sophistication of analyses, and practical limits on full reporting of results. In many cases, cross-study differences in sample composition and measurements impede or lessen the utility of pooled data analysis. A collaborative, coordinated analysis approach can provide a broad foundation for cumulating scientific knowledge by facilitating efficient analysis of multiple studies in ways that maximize comparability of results and permit evaluation of study differences. The goal of such an approach is to maximize opportunities for replication and extension of findings across longitudinal studies through open access to analysis scripts and output for published results, permitting modification, evaluation, and extension of alternative statistical models and application to additional data sets. Drawing on the cognitive aging literature as an example, the authors articulate some of the challenges of meta-analytic and pooled-data approaches and introduce a coordinated analysis approach as an important avenue for maximizing the comparability, replication, and extension of results from longitudinal studies. PMID:19485626

  19. Coordinated measurements made by the Sondrestrom radar and the Polar Bear ultraviolet imager

    SciTech Connect

    Robinson, R.; Vondrak, R. ); Dabbs, T.; Vickrey, J. ); Eastes, R.; Del Greco, F.; Huffman, R. ); Meng, C. ); Daniell, R.; Strickland, D.; Vondrak, R. )

    1992-03-01

    In 1986 and 1987 the Sondrestrom incoherent scatter radar in Greenland was operated routinely in coordination with selected overpasses of the Polar Bear satellite. For these experiments the auroral ionospheric remote sensor on Polar Bear obtained images of auroral emissions in two far ultraviolet wavelength bands centered at approximately 136 and 160 nm and one visible band centered at 391.4 nm. Measurements at these three wavelengths were extracted from the images for comparison with the coincident radar measurements. Model calculations have shown that for Maxwellian incident electron distributions the ratio between the 136-nm luminosity and 391.4-nm luminosity can be used to estimate the mean energy of precipitating electrons. Once the mean energy is known, then either of the two emissions can be used to determine the total energy flux. This procedure is used to determine the properties of the incident electron distribution during three midnight sector auroral events over Sondre Stromfjord. The incident electron flux is then used to calculate the expected height profile of electron density which is compared with the simultaneous and coincident radar measurements. The results show that the derived profiles agree well with the measured profiles both in the peak electron density and the altitude of the peak. The accuracy with which the peak of the profile is predicted by this technique is such that many important ionospheric parameters can be reliably inferred from remote measurements, including, for example, the height-integrated electrical conductivities.

  20. Coordination and Hydrolysis of Plutonium Ions in Aqueous Solution using Car-Parrinello Molecular Dynamics Free Energy Simulations

    SciTech Connect

    Odoh, Samuel O.; Bylaska, Eric J.; De Jong, Wibe A.

    2013-11-27

    Car-Parrinello molecular dynamics (CPMD) simulations have been used to examine the hydration structures, coordination energetics and the first hydrolysis constants of Pu3+, Pu4+, PuO2+ and PuO22+ ions in aqueous solution at 300 K. The coordination numbers and structural properties of the first shell of these ions are in good agreement with available experimental estimates. The hexavalent PuO22+ species is coordinated to 5 aquo ligands while the pentavalent PuO2+ complex is coordinated to 4 aquo ligands. The Pu3+ and Pu4+ ions are both coordinated to 8 water molecules. The first hydrolysis constants obtained for Pu3+ and PuO22+ are 6.65 and 5.70 respectively, all within 0.3 pH units of the experimental values (6.90 and 5.50 respectively). The hydrolysis constant of Pu4+, 0.17, disagrees with the value of -0.60 in the most recent update of the Nuclear Energy Agency Thermochemical Database (NEA-TDB) but supports recent experimental findings. The hydrolysis constant of PuO2+, 9.51, supports the experimental results of Bennett et al. (Radiochim. Act. 1992, 56, 15). A correlation between the pKa of the first hydrolysis reaction and the effective charge of the plutonium center was found.

  1. Measurements and analysis of end-to-end Internet dynamics

    SciTech Connect

    Paxson, V

    1997-04-01

    Accurately characterizing end-to-end Internet dynamics - the performance that a user actually obtains from the lengthy series of network links that comprise a path through the Internet - is exceptionally difficult, due to the network`s immense heterogeneity. At the heart of this work is a `measurement framework` in which a number of sites around the Internet host a specialized measurement service. By coordinating `probes` between pairs of these sites one can measure end-to-end behavior along O(N{sup 2}) paths for a framework consisting of N sites. Consequently, one obtains a superlinear scaling that allows measuring a rich cross-section of Internet behavior without requiring huge numbers of observation points. 37 sites participated in this study, allowing the author to measure more than 1,000 distinct Internet paths. The first part of this work looks at the behavior of end-to-end routing: the series of routers over which a connection`s packets travel. Based on 40,000 measurements made using this framework, the author analyzes: routing `pathologies` such as loops, outages, and flutter; the stability of routes over time; and the symmetry of routing along the two directions of an end-to-end path. The author finds that pathologies increased significantly over the course of 1995 and that Internet paths are heavily dominated by a single route. The second part of this work studies end-to-end Internet packet dynamics. The author analyzes 20,000 TCP transfers of 100 Kbyte each to investigate the performance of both the TCP endpoints and the Internet paths. The measurements used for this part of the study are much richer than those for the first part, but require a great degree of attention to issues of calibration, which are addressed by applying self-consistency checks to the measurements whenever possible. The author finds that packet filters are capable of a wide range of measurement errors, some of which, if undetected, can significantly taint subsequent analysis.

  2. Measuring multipartite entanglement through dynamic susceptibilities

    NASA Astrophysics Data System (ADS)

    Hauke, Philipp; Heyl, Markus; Tagliacozzo, Luca; Zoller, Peter

    2016-08-01

    Entanglement is considered an essential resource in quantum technologies, and central to the understanding of quantum many-body physics. Developing protocols to detect and quantify the entanglement of many-particle quantum states is thus a key challenge for present experiments. Here, we show that the quantum Fisher information, a witness for genuinely multipartite entanglement, becomes measurable for thermal ensembles by means of the dynamic susceptibility--that is, with resources readily available in present cold atomic-gas and condensed-matter experiments. This establishes a connection between multipartite entanglement and many-body correlations contained in response functions, with immediate implications close to quantum phase transitions, where the quantum Fisher information becomes universal, allowing us to identify strongly entangled phase transitions with a divergent multipartite entanglement. We illustrate our framework using paradigmatic quantum Ising models, and point out potential signatures in optical-lattice experiments and strongly correlated materials.

  3. Improvement in the assessment of wear of total knee replacements using coordinate-measuring machine techniques.

    PubMed

    Blunt, L A; Bills, P J; Jiang, X-Q; Chakrabarty, G

    2008-04-01

    Total joint replacement is one of the most common elective surgical procedures performed worldwide, with an estimate of 1.5x 10(6) operations performed annually. Currently joint replacements are expected to function for 10-15 years; however, with an increase in life expectancy, and a greater call for knee replacement due to increased activity levels, there is a requirement to improve their function to offer longer-term improved quality of life for patients. Wear analysis of total joint replacements has long been an important means in determining failure mechanisms and improving longevity of these devices. The effectiveness of the coordinate-measuring machine (CMM) technique for assessing volumetric material loss during simulated life testing of a replacement knee joint has been proved previously by the present authors. The purpose of the current work is to present an improvement to this method for situations where no pre-wear data are available. To validate the method, simulator tests were run and gravimetric measurements taken throughout the test, such that the components measured had a known wear value. The implications of the results are then discussed in terms of assessment of joint functionality and development of standardized CMM-based product standards. The method was then expanded to allow assessment of clinically retrieved bearings so as to ascertain a measure of true clinical wear.

  4. Manual function outcome measures in children with developmental coordination disorder (DCD): Systematic review.

    PubMed

    Bieber, Eleonora; Smits-Engelsman, Bouwien C M; Sgandurra, Giuseppina; Cioni, Giovanni; Feys, Hilde; Guzzetta, Andrea; Klingels, Katrijn

    2016-08-01

    This study systematically reviewed the clinical and psychometric properties of manual function outcome measures for children with developmental coordination disorder (DCD) aged 3-18 years. Three electronic databases were searched to identify manual function tools at the ICF-CY body function, activity and participation level used in children with DCD. Study selection and data extraction was conducted by two blind assessors according to the CanChild Outcome Measures Rating Form. Nineteen clinical tests (seven fine hand use tools and 12 handwriting measures), three naturalistic observations and six questionnaires were identified. The fine-motor subdomain of the Movement Assessment Battery for Children, the Bruininks-Oseretsky Test of Motor Proficiency-2 and the Functional Strength Measurement, with adequate reliability and validity properties, might be useful for manual function capacity assessment. The Systematic Detection of Writing Problems (SOS) and the Detailed Assessment of Speed of Handwriting (DASH) could be adopted for handwriting assessment, respectively from 6 and 9 years old. Naturalistic observations and questionnaires, whose psychometric properties have been investigated into limited extent, offer an assessment of the daily performances. This review shows that a combination of different tools is needed for a comprehensive assessment of manual function in children with DCD including the three levels of the ICF-CY. Further investigation of psychometric properties of those tools in children with DCD is warranted. Tests validated in other populations should be explored for their applicability for assessing manual function in children with DCD.

  5. Non-coincident Inter-instrument Comparisons of Ozone Measurements Using Quasi-conservative Coordinates

    NASA Technical Reports Server (NTRS)

    Lait, L. R.; Newman, P. A.; Schoeberl, M. R.; McGee, T.; Twigg, T.; Browell, E.; Bevilacqua, R.; Andersen, S. B.; DeBacker, H.; Benesova, A.

    2004-01-01

    Ozone measurements from ozonesondes, AROTAL, DIAL, and POAM III instruments during the SOLVE-2/VINTERSOL period are composited in a time-varying, flow-following quasi-conservative (PV-6) coordinate space; the resulting composites from each instrument are mapped onto the other instruments locations and times. The mapped data are then used to intercompare data from the different instruments. Overall, the four data sets are found to be in good agreement. AROTAL shows somewhat lower values below 16 km, and DIAL has a positive bias at the upper limits of its altitude range. These intercomparisons are consistent with those obtained from more conventional near-coincident profiles, where available. Although the PV-theta mapping technique entails larger uncertainties of individual profile differences compared to direct near-coincident comparisons, the ability to include much larger numbers of comparisons can make this technique advantageous.

  6. Hawking Radiation and Entropy of a Dynamic Dilaton-Maxwell Black Hole with a New Tortoise Coordinate Transformation

    NASA Astrophysics Data System (ADS)

    Lan, Xiao-Gang

    2013-05-01

    By introducing a new tortoise coordinate transformation, we apply Damour-Ruffini-Sannan method to study the Hawking radiation of massive scalar particles in a dynamic Dilaton-Maxwell black hole. We find that Hawking radiation spectrum shows still the blackbody one, while the Hawking temperature is significantly changed. Additionally, by adopting the thin film method, we calculate the entropy of a dynamic Dilaton-Maxwell black hole. The result indicates that the entropy for such a black hole is still in proportional to the area of its event horizon.

  7. Using a coordinate measuring machine to calibrate step gages at world class levels of uncertainty

    SciTech Connect

    Zurcher, N.

    1996-08-01

    The purpose of this paper is to relate some of the experiences of using a coordinate measuring machine (CMM) to calibrate long end standards and step gages at measurement uncertainties of less than 0. 5{mu}m. It is not the intent of this paper to suggest that everyone should return to his or her laboratory and change the way CMMs are operated nor to suggest that the methods discussed here are even the best methods. The intent is to provide some food for thought, based on real experiences, about the use of a CMM to measure at low levels of uncertainty. As will become apparent, a lot of the issues discussed really apply to any dimensional measuring technique operating at low levels of uncertainty, not just a CMM. The discussion in this paper is based on measuring one-dimensional end standards and step gages placed along the x-axis of the Moore M-60 CMM located at the Oak Ridge Metrology Center, which is part of the Oak Ridge Centers for Manufacturing Technology at the Y-12 Plant (formerly used in manufacturing nuclear weapons parts) in Oak Ridge, Tennessee. When the Cold War ended, the U.S. Department of Energy (DOE) pushed to make nuclear weapons technology available to U.S. industry. As part of this technology transfer effort, it was determined that the M-60 could be used by the National Institute of Standards and Technology (NIST) to provide a calibration service for step gages. Previously, U.S. industrialists had to go to Germany for step gage calibrations at the lowest levels of measurement uncertainty. Much of the discussion that follows is based on the process developed to use the M-60 for the NIST calibration.

  8. Fluid dynamic factors in tracheal pressure measurement.

    PubMed

    Chang, H K; Mortola, J P

    1981-07-01

    Because tracheal pressure measurement generally involves the use of a cannula or an endotracheal tube, fluid dynamic factors may cause a considerable artifact. We present a theoretical explanation of the observed apparent paradox in which the resistance of a tracheal cannula or an endotracheal tube is isolation was found to exceed the resistance of the airways plus the cannula or the tube in situ. By estimating the viscous dissipation and the kinetic energy change in a conduit with sudden variation of cross-sectional area, a predictive model is derived. The predictions are verified by a series of in vitro experiments with both steady and oscillatory flows. The experiments showed that the pressure recorded from the sidearm of a tracheal cannula or endotracheal tube contains an error which, in general, increased with the mean Reynolds' number of the through flow and also depends on the diameter ratio between the trachea and the tube or cannula, the position of the pressure tap, and the frequency of ventilation. When feasible, direct measurement with a needle in the trachea is suggested as a way to avoid the possible artifacts arising from the use fo a side tap of the cannula. Theoretical considerations, as well as in vitro and animal experiments, indicate that adding a properly chosen expansion to the tracheal cannula makes it possible to alter inspiratory and expiratory pressures selectively. This device may prove useful in control of breathing studies. PMID:7263418

  9. A PLM-based automated inspection planning system for coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Zhao, Haibin; Wang, Junying; Wang, Boxiong; Wang, Jianmei; Chen, Huacheng

    2006-11-01

    With rapid progress of Product Lifecycle Management (PLM) in manufacturing industry, automatic generation of inspection planning of product and the integration with other activities in product lifecycle play important roles in quality control. But the techniques for these purposes are laggard comparing with techniques of CAD/CAM. Therefore, an automatic inspection planning system for Coordinate Measuring Machine (CMM) was developed to improve the automatization of measuring based on the integration of inspection system in PLM. Feature information representation is achieved based on a PLM canter database; measuring strategy is optimized through the integration of multi-sensors; reasonable number and distribution of inspection points are calculated and designed with the guidance of statistic theory and a synthesis distribution algorithm; a collision avoidance method is proposed to generate non-collision inspection path with high efficiency. Information mapping is performed between Neutral Interchange Files (NIFs), such as STEP, DML, DMIS, XML, etc., to realize information integration with other activities in the product lifecycle like design, manufacturing and inspection execution, etc. Simulation was carried out to demonstrate the feasibility of the proposed system. As a result, the inspection process is becoming simpler and good result can be got based on the integration in PLM.

  10. Evaluation on the probing error of a micro-coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Chao, Z. X.; Tan, S. L.; Xu, G.

    2008-09-01

    Micro-coordinate measuring machines (micro-CMMs) with small probes (φ300 μm or smaller), low probing force and high accuracy working stage have been developed in recent years for three-dimensional (3D) measurement of micro structures. In general, the performance of the micro-CMM depends on the accuracy of its working stage and the probing system. The accuracy of the working stage of a micro CMM can be assessed by laser interferometry to the order of a few tens of nanometers. However, the accuracy of its probing system is difficult to assess due to the small probe size and low probing force. The probing error of a micro-CMM (model F25 by Carl Zeiss) was investigated at our laboratory. The probes used in the system are based on silicon membrane and piezo-resistive elements. The stylus size of the probes ranges from φ120 μm to φ300 μm. The effect of various sources, including the stylus size, on the probing error of the system was evaluated by means of certified precision spheres with reference to ISO 10360-2:2001. Based on the results obtained, possible ways to reduce the probing error are discussed. This is illustrated by the uncertainty analysis of the diameter measurements of a ring gauge using the system.

  11. The dynamics of information-driven coordination phenomena: A transfer entropy analysis

    PubMed Central

    Borge-Holthoefer, Javier; Perra, Nicola; Gonçalves, Bruno; González-Bailón, Sandra; Arenas, Alex; Moreno, Yamir; Vespignani, Alessandro

    2016-01-01

    Data from social media provide unprecedented opportunities to investigate the processes that govern the dynamics of collective social phenomena. We consider an information theoretical approach to define and measure the temporal and structural signatures typical of collective social events as they arise and gain prominence. We use the symbolic transfer entropy analysis of microblogging time series to extract directed networks of influence among geolocalized subunits in social systems. This methodology captures the emergence of system-level dynamics close to the onset of socially relevant collective phenomena. The framework is validated against a detailed empirical analysis of five case studies. In particular, we identify a change in the characteristic time scale of the information transfer that flags the onset of information-driven collective phenomena. Furthermore, our approach identifies an order-disorder transition in the directed network of influence between social subunits. In the absence of clear exogenous driving, social collective phenomena can be represented as endogenously driven structural transitions of the information transfer network. This study provides results that can help define models and predictive algorithms for the analysis of societal events based on open source data. PMID:27051875

  12. The dynamics of information-driven coordination phenomena: A transfer entropy analysis.

    PubMed

    Borge-Holthoefer, Javier; Perra, Nicola; Gonçalves, Bruno; González-Bailón, Sandra; Arenas, Alex; Moreno, Yamir; Vespignani, Alessandro

    2016-04-01

    Data from social media provide unprecedented opportunities to investigate the processes that govern the dynamics of collective social phenomena. We consider an information theoretical approach to define and measure the temporal and structural signatures typical of collective social events as they arise and gain prominence. We use the symbolic transfer entropy analysis of microblogging time series to extract directed networks of influence among geolocalized subunits in social systems. This methodology captures the emergence of system-level dynamics close to the onset of socially relevant collective phenomena. The framework is validated against a detailed empirical analysis of five case studies. In particular, we identify a change in the characteristic time scale of the information transfer that flags the onset of information-driven collective phenomena. Furthermore, our approach identifies an order-disorder transition in the directed network of influence between social subunits. In the absence of clear exogenous driving, social collective phenomena can be represented as endogenously driven structural transitions of the information transfer network. This study provides results that can help define models and predictive algorithms for the analysis of societal events based on open source data. PMID:27051875

  13. Aging induced loss of complexity and dedifferentiation: consequences for coordination dynamics within and between brain, muscular and behavioral levels.

    PubMed

    Sleimen-Malkoun, Rita; Temprado, Jean-Jacques; Hong, S Lee

    2014-01-01

    Growing evidence demonstrates that aging not only leads to structural and functional alterations of individual components of the neuro-musculo-skeletal system (NMSS) but also results in a systemic re-organization of interactions within and between the different levels and functional domains. Understanding the principles that drive the dynamics of these re-organizations is an important challenge for aging research. The present Hypothesis and Theory paper is a contribution in this direction. We propose that age-related declines in brain and behavior that have been characterized in the literature as dedifferentiation and the loss of complexity (LOC) are: (i) synonymous; and (ii) integrated. We argue that a causal link between the aforementioned phenomena exists, evident in the dynamic changes occurring in the aging NMSS. Through models and methods provided by a dynamical systems approach to coordination processes in complex living systems, we: (i) formalize operational hypotheses about the general principles of changes in cross-level and cross-domain interactions during aging; and (ii) develop a theory of the aging NMSS based on the combination of the frameworks of coordination dynamics (CD), dedifferentiation, and LOC. Finally, we provide operational predictions in the study of aging at neural, muscular, and behavioral levels, which lead to testable hypotheses and an experimental agenda to explore the link between CD, LOC and dedifferentiation within and between these different levels.

  14. Aging induced loss of complexity and dedifferentiation: consequences for coordination dynamics within and between brain, muscular and behavioral levels

    PubMed Central

    Sleimen-Malkoun, Rita; Temprado, Jean-Jacques; Hong, S. Lee

    2014-01-01

    Growing evidence demonstrates that aging not only leads to structural and functional alterations of individual components of the neuro-musculo-skeletal system (NMSS) but also results in a systemic re-organization of interactions within and between the different levels and functional domains. Understanding the principles that drive the dynamics of these re-organizations is an important challenge for aging research. The present Hypothesis and Theory paper is a contribution in this direction. We propose that age-related declines in brain and behavior that have been characterized in the literature as dedifferentiation and the loss of complexity (LOC) are: (i) synonymous; and (ii) integrated. We argue that a causal link between the aforementioned phenomena exists, evident in the dynamic changes occurring in the aging NMSS. Through models and methods provided by a dynamical systems approach to coordination processes in complex living systems, we: (i) formalize operational hypotheses about the general principles of changes in cross-level and cross-domain interactions during aging; and (ii) develop a theory of the aging NMSS based on the combination of the frameworks of coordination dynamics (CD), dedifferentiation, and LOC. Finally, we provide operational predictions in the study of aging at neural, muscular, and behavioral levels, which lead to testable hypotheses and an experimental agenda to explore the link between CD, LOC and dedifferentiation within and between these different levels. PMID:25018731

  15. Spin-labelled cyclometallated palladium complexes. EPR study of dynamic processes in coordination sphere

    NASA Astrophysics Data System (ADS)

    Kozhanov, K. A.; Bubnov, M. P.; Abakumov, G. A.; Cherkasov, V. K.

    2012-12-01

    New four-, five- and six-coordinated cyclometallated o-semiquinonato palladium complexes were obtained and characterized in solution by EPR. Interaction of square-planar azaphenyl palladium semiquinonate with mono and bidentate phosphane donors leads to formation of five- and six-coordinated adducts. Typical values of HFC constants on apical and basal phosphorouses are observed for such compounds. In one case the reversible addition of tri-phenyl-phosphane was observed. The coordination mode of pincer ligand (bi- or tridentate) in o-semiquinonato pincer complexes depends on the nature of linker between coordinating group and pincer aryl ring. In the case of sbnd CH2sbnd linker five coordinated complexes are formed. The "swing" and "fan" oscillations are observed for these compounds. Complexes with sbnd Osbnd linker are the first examples of compounds with bidentate bonded phosphorous-based pincer ligand. Most of complexes are unstable and decompose during some hours. Only the application of o-semiquinones as spin labels and using the EPR technique made possible to observe and interpret their structure.

  16. Subcellular and Dynamic Coordination between Src Activity and Cell Protrusion in Microenvironment

    PubMed Central

    Zhuo, Yue; Qian, Tongcheng; Wu, Yiqian; Seong, Jihye; Gong, Ya; Ma, Hongwei; Wang, Yingxiao; Lu, Shaoying

    2015-01-01

    Migration of endothelial cells is essential for wound healing and angiogenesis. Src kinase activity plays important roles at the protrusions of migrating endothelial cells. However, the spatiotemporal coordination between Src kinase activity and the protrusion of cell edge remains unclear. Therefore, we investigate these coordinated molecular events at the initiation of cell migration, by integrating microfabrication, fluorescence resonance energy transfer (FRET)-based biosensors, and automated computational image analysis. We demonstrate that the physical release of restrictive micropattern triggered a significant decrease of Src activity at the protrusive edge of endothelial cells. Computational cross-correlation analysis reveals that the decrease of Src activity occurred earlier in time, and was well-coordinated with the protrusion of cell edge in polarized cells, but not in non-polarized cells. These results suggest that the spatiotemporal control of Src kinase activity is well-coordinated with cell polarization and protrusion in endothelial cells upon the release of physical constraint, as that experienced by endothelial cells sprouting from stiff tumor micro-environment during angiogenesis. Therefore, our integrative approach enabled the discovery of a new model where Src is de-activated in coordination with membrane protrusion, providing important insights into the regulation of endothelial migration and angiogenesis. PMID:26261043

  17. SPC techniques for the M-48 Coordinate Measurement Machine applied to uncertainty analysis and monitoring

    SciTech Connect

    Escher, R.N. Jr.

    1998-04-14

    The Moore M-48 Coordinate Measuring Machine (CMM) is used to calibrate step gages, ball bars and hole plates. The expanded uncertainty (2 sigma) of the M-48 CMM was determined to be {+-}0.3 + 0.4 L microns (L is length in meters), using the decomposition method. The problem statement becomes, how does one monitor and control the calibration process to ensure that one maintains this level of reliability? Traditional methods of statistical process control, such as X-bar and R charts assume large lot production and are designed to detect changes in the process being monitored. Since calibrations are performed one at a time, with sometimes years between calibrations, standard control charting methodology falls a bit short of what is needed to maintain process capability. Upon examination of the process uncertainty for the M-48 CMM the author finds the following parameters play an important roll in process capability. Since the M-48 uses laser scales, the Edlen equation is used to convert pressure, temperature and humidity to wavelength correction. The largest source of uncertainty comes from temperature effects based on gradients, accuracy of the thermistors and the actual coefficient of thermal expansion of the artifact. The probe calibration, which is performed for each calibration, is another important variable. Since the M-48 CMM`s movement is very slow, drift is also an important parameter to monitor. The paper describes the selection of check standards and measurement protocol made.

  18. Geometrically motivated coordinate system for exploring spacetime dynamics in numerical-relativity simulations using a quasi-Kinnersley tetrad

    NASA Astrophysics Data System (ADS)

    Zhang, Fan; Brink, Jeandrew; Szilágyi, Béla; Lovelace, Geoffrey

    2012-10-01

    We investigate the suitability and properties of a quasi-Kinnersley tetrad and a geometrically motivated coordinate system as tools for quantifying both strong-field and wave-zone effects in numerical relativity (NR) simulations. We fix two of the coordinate degrees of freedom of the metric, namely, the radial and latitudinal coordinates, using the Coulomb potential associated with the quasi-Kinnersley transverse frame. These coordinates are invariants of the spacetime and can be used to unambiguously fix the outstanding spin-boost freedom associated with the quasi-Kinnersley frame (and thus can be used to choose a preferred quasi-Kinnersley tetrad). In the limit of small perturbations about a Kerr spacetime, these geometrically motivated coordinates and quasi-Kinnersley tetrad reduce to Boyer-Lindquist coordinates and the Kinnersley tetrad, irrespective of the simulation gauge choice. We explore the properties of this construction both analytically and numerically, and we gain insights regarding the propagation of radiation described by a super-Poynting vector, further motivating the use of this construction in NR simulations. We also quantify in detail the peeling properties of the chosen tetrad and gauge. We argue that these choices are particularly well-suited for a rapidly converging wave-extraction algorithm as the extraction location approaches infinity, and we explore numerically the extent to which this property remains applicable on the interior of a computational domain. Using a number of additional tests, we verify numerically that the prescription behaves as required in the appropriate limits regardless of simulation gauge; these tests could also serve to benchmark other wave extraction methods. We explore the behavior of the geometrically motivated coordinate system in dynamical binary-black-hole NR mergers; while we obtain no unexpected results, we do find that these coordinates turn out to be useful for visualizing NR simulations (for example, for

  19. Evaluation of a Care Coordination Measure for the Consumer Assessment of Healthcare Providers and Systems (CAHPS®) Medicare Survey

    PubMed Central

    Hays, Ron D.; Martino, Steven; Brown, Julie A.; Cui, Mike; Cleary, Paul; Gaillot, Sarah; Elliott, Marc

    2014-01-01

    There is widespread interest in assessing care coordination to improve overall care quality. We evaluated a five-item measure of care coordination included in the 2012 Consumer Assessment of Healthcare Providers and Systems (CAHPS) Medicare survey (n=326,194 respondents, 46% response rate). This measure includes patient reports of whether their personal doctor discusses their medicines, has medical records and other relevant information, and is informed about care from specialists; and whether the patient gets help in managing care and timely follow-up on test results. A one-factor categorical confirmatory factor analytic model indicated that five items constituted a coherent scale. Estimated health-plan level reliability was 0.70 at about 102 responses per plan.. The composite had a strong unique association with the CAHPS global rating of health care, controlling for the CAHPS core composite scores. This measure can be used to evaluate relative plan performance and characteristics associated with better care coordination. PMID:24227813

  20. Dimensional characterization of a quasispherical resonator by microwave and coordinate measurement techniques

    NASA Astrophysics Data System (ADS)

    Underwood, R.; Flack, D.; Morantz, P.; Sutton, G.; Shore, P.; de Podesta, M.

    2011-02-01

    We describe the dimensional characterization of copper quasisphere NPL-Cranfield 2. The quasisphere is assembled from two hemispheres such that the internal shape is a triaxial ellipsoid, the major axes of which have nominal radii 62.000 mm, 62.031 mm and 62.062 mm. The artefact has been manufactured using diamond-turning technology and shows a deviation from design form of less than ±1 µm over most of its surface. Our characterization involves both coordinate measuring machine (CMM) experiments and microwave resonance spectroscopy. We have sought to reduce the dimensional uncertainty below the maximum permissible error of the CMM by comparative measurements with silicon and Zerodur spheres of known volume. Using this technique we determined the equivalent radius with an uncertainty of u(k = 1) = 114 nm, a fractional uncertainty of 1.8 parts in 106. Due to anisotropy of the probe response, we could only determine the eccentricities of the quasihemispheres with a fractional uncertainty of approximately 2%. Our microwave characterization uses the TM11 to TM18 resonances. We find the equivalent radius inferred from analysis of these modes to be consistent within ±4 nm with an overall uncertainty u(k = 1) = 11 nm. We discuss corrections for surface conductivity, waveguide perturbations and dielectric surface layers. We find that the CMM radius estimates derived from each hemisphere cannot be used to accurately predict the equivalent radius of the assembled resonator for two reasons. Firstly, the equatorial flanges are flat only to within ±1 µm, leading to an equatorial 'gap' whose dimension cannot be reliably estimated. Secondly, the resonator undergoes significant elastic distortion when the bolts connecting the hemispheres are tightened. We provide CMM and microwave measurements to support these conclusions in addition to finite-element modelling. Finally, we consider the implications of this work on a forthcoming experiment to determine the Boltzmann constant

  1. Analyzing Group Coordination when Solving Geometry Problems with Dynamic Geometry Software

    ERIC Educational Resources Information Center

    Oner, Diler

    2013-01-01

    In CSCL research, collaborative activity is conceptualized along various yet intertwined dimensions. When functioning within these multiple dimensions, participants make use of several resources, which can be social or content-related (and sometimes temporal) in nature. It is the effective coordination of these resources that appears to…

  2. Coordination chemistry strategies for dynamic helicates: time-programmable chirality switching with labile and inert metal helicates.

    PubMed

    Miyake, Hiroyuki; Tsukube, Hiroshi

    2012-11-01

    'Chirality switching' is one of the most important chemical processes controlling many biological systems. DNAs and proteins often work as time-programmed functional helices, in which specific external stimuli alter the helical direction and tune the time scale of subsequent events. Although a variety of organic foldamers and their hybrids with natural helices have been developed, we highlight coordination chemistry strategies for development of structurally and functionally defined metal helicates. These metal helicates have characteristic coordination geometries, redox reactivities and spectroscopic/magnetic properties as well as complex chiralities. Several kinds of inert metal helicates maintain rigid helical structures and their stereoisomers are separable by optical resolution techniques, while labile metal helicates offer dynamic inversion of their helical structures via non-covalent interactions with external chemical signals. The latter particularly have dynamically ordered helical structures, which are controlled by the combinations of metal centres and chiral ligands. They further function as time-programmable switches of chirality-derived dynamic rotations, translations, stretching and shape flipping, which are useful applications in nanoscience and related technology.

  3. Empirical force field for cisplatin based on quantum dynamics data: case study of new parameterization scheme for coordination compounds.

    PubMed

    Yesylevskyy, S; Cardey, Bruno; Kraszewski, S; Foley, Sarah; Enescu, Mironel; da Silva, Antônio M; Dos Santos, Hélio F; Ramseyer, Christophe

    2015-10-01

    Parameterization of molecular complexes containing a metallic compound, such as cisplatin, is challenging due to the unconventional coordination nature of the bonds which involve platinum atoms. In this work, we develop a new methodology of parameterization for such compounds based on quantum dynamics (QD) calculations. We show that the coordination bonds and angles are more flexible than in normal covalent compounds. The influence of explicit solvent is also shown to be crucial to determine the flexibility of cisplatin in quantum dynamics simulations. Two empirical topologies of cisplatin were produced by fitting its atomic fluctuations against QD in vacuum and QD with explicit first solvation shell of water molecules respectively. A third topology built in a standard way from the static optimized structure was used for comparison. The later one leads to an excessively rigid molecule and exhibits much smaller fluctuations of the bonds and angles than QD reveals. It is shown that accounting for the high flexibility of cisplatin molecule is needed for adequate description of its first hydration shell. MD simulations with flexible QD-based topology also reveal a significant decrease of the barrier of passive diffusion of cisplatin accross the model lipid bilayer. These results confirm that flexibility of organometallic compounds is an important feature to be considered in classical molecular dynamics topologies. Proposed methodology based on QD simulations provides a systematic way of building such topologies.

  4. Recurrent geomagnetic storms and relativistic electron enhancements in the outer magnetosphere: ISTP coordinated measurements

    SciTech Connect

    Baker, D.N.; Li, X.; Turner, N.; Allen, J.H.; Blake, J.B.; Sheldon, R.B.; Spence, H.E.; Belian, R.D.; Reeves, G.D.; Kanekal, S.G.; Lepping, R.P.; Ogilvie, K.; Mewaldt, R.A.; Onsager, T.; Singer, H.J.

    1997-07-01

    New, coordinated measurements from the International Solar-Terrestrial Physics (ISTP) constellation of spacecraft are presented to show the causes and effects of recurrent geomagnetic activity during recent solar minimum conditions. It is found using WIND and POLAR data that even for modest geomagnetic storms, relativistic electron fluxes are strongly and rapidly enhanced within the outer radiation zone of the Earth{close_quote}s magnetosphere. Solar wind data are utilized to identify the drivers of magnetospheric acceleration processes. Yohkoh solar soft X-ray data are also used to identify the solar coronal holes that produce the high-speed solar wind streams which, in turn, cause the recurrent geomagnetic activity. It is concluded that even during extremely quiet solar conditions (sunspot minimum) there are discernible coronal holes and resultant solar wind streams which can produce intense magnetospheric particle acceleration. As a practical consequence of this Sun-Earth connection, it is noted that a long-lasting E{gt}1MeV electron event in late March 1996 appears to have contributed significantly to a major spacecraft (Anik E1) operational failure.{copyright} 1997 American Geophysical Union

  5. Hydrothermal alteration and diagenesis of terrestrial lacustrine pillow basalts: Coordination of hyperspectral imaging with laboratory measurements

    NASA Astrophysics Data System (ADS)

    Greenberger, Rebecca N.; Mustard, John F.; Cloutis, Edward A.; Mann, Paul; Wilson, Janette H.; Flemming, Roberta L.; Robertson, Kevin M.; Salvatore, Mark R.; Edwards, Christopher S.

    2015-12-01

    We investigate an outcrop of ∼187 Ma lacustrine pillow basalts of the Talcott Formation exposed in Meriden, Connecticut, USA, focusing on coordinated analyses of one pillow lava to characterize the aqueous history of these basalts in the Hartford Basin. This work uses a suite of multidisciplinary measurements, including hyperspectral imaging, other spectroscopic techniques, and chemical and mineralogical analyses, from the microscopic scale up to the scale of an outcrop. The phases identified in the sample are albite, large iron oxides, and titanite throughout; calcite in vesicles; calcic clinopyroxene, aegirine, and Fe/Mg-bearing clay in the rind; and fine-grained hematite and pyroxenes in the interior. Using imaging spectroscopy, the chemistry and mineralogy results extend to the hand sample and larger outcrop. From all of the analyses, we suggest that the pillow basalts were altered initially after emplacement, either by heated lake water or magmatic fluids, at temperatures of at least 400-600 °C, and the calcic clinopyroxenes and aegirine identified in the rind are a preserved record of that alteration. As the hydrothermal system cooled to slightly lower temperatures, clays formed in the rind, and, during this alteration, the sample oxidized to form hematite in the matrix of the interior and Fe3+ in the pyroxenes in the rind. During the waning stages of the hydrothermal system, calcite precipitated in vesicles within the rind. Later, diagenetic processes albitized the sample, with albite replacing plagioclase, lining vesicles, and accreting onto the exterior of the sample. This albitization or Na-metasomatism occurred when the lake within the Hartford Basin evaporated during a drier past climatic era, resulting in Na-rich brines. As Ca-rich plagioclase altered to albite, Ca was released into solution, eventually precipitating as calcite in previously-unfilled vesicles, dominantly in the interior of the pillow. Coordinated analyses of this sample permit

  6. Dynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage

    PubMed Central

    Wamstad, Joseph A.; Alexander, Jeffrey M.; Truty, Rebecca M.; Shrikumar, Avanti; Li, Fugen; Eilertson, Kirsten E.; Ding, Huiming; Wylie, John N.; Pico, Alexander R.; Capra, John A.; Erwin, Genevieve; Kattman, Steven J.; Keller, Gordon M.; Srivastava, Deepak; Levine, Stuart S.; Pollard, Katherine S.; Holloway, Alisha K.; Boyer, Laurie A.; Bruneau, Benoit G.

    2012-01-01

    SUMMARY Heart development is exquisitely sensitive to the precise temporal regulation of thousands of genes that govern developmental decisions during differentiation. However, we currently lack a detailed understanding of how chromatin and gene expression patterns are coordinated during developmental transitions in the cardiac lineage. Here, we interrogated the transcriptome and several histone modifications across the genome during defined stages of cardiac differentiation. We find distinct chromatin patterns that are coordinated with stage-specific expression of functionally related genes, including many human disease-associated genes. Moreover, we discover a novel pre-activation chromatin pattern at the promoters of genes associated with heart development and cardiac function. We further identify stage-specific distal enhancer elements and find enriched DNA binding motifs within these regions that predict sets of transcription factors that orchestrate cardiac differentiation. Together, these findings form a basis for understanding developmentally regulated chromatin transitions during lineage commitment and the molecular etiology of congenital heart disease. PMID:22981692

  7. Beyond the Niche: Tissue-Level Coordination of Stem Cell Dynamics

    PubMed Central

    O’Brien, Lucy Erin; Bilder, David

    2014-01-01

    Adult animals rely on populations of stem cells to ensure organ function throughout their lifetime. Stem cells are governed by signals from stem cell niches, and much is known about how single niches promote stemness and direct stem cell behavior. However, most organs contain a multitude of stem cell–niche units, which are often distributed across the entire expanse of the tissue. Beyond the biology of individual stem cell–niche interactions, the next challenge is to uncover the tissue-level processes that orchestrate spatial control of stem-based renewal, repair, and remodeling throughout a whole organ. Here we examine what is known about higher order mechanisms for interniche coordination in epithelial organs, whose simple geometry offers a promising entry point for understanding the regulation of niche number, distribution, and activity. We also consider the potential existence of stem cell territories and how tissue architecture may influence niche coordination. PMID:23937350

  8. Dynamic Forces in Spur Gears - Measurement, Prediction, and Code Validation

    NASA Technical Reports Server (NTRS)

    Oswald, Fred B.; Townsend, Dennis P.; Rebbechi, Brian; Lin, Hsiang Hsi

    1996-01-01

    Measured and computed values for dynamic loads in spur gears were compared to validate a new version of the NASA gear dynamics code DANST-PC. Strain gage data from six gear sets with different tooth profiles were processed to determine the dynamic forces acting between the gear teeth. Results demonstrate that the analysis code successfully simulates the dynamic behavior of the gears. Differences between analysis and experiment were less than 10 percent under most conditions.

  9. CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation.

    PubMed

    Tan, Minghui; Cha, Caihui; Ye, Yongheng; Zhang, Jifeng; Li, Sumei; Wu, Fengming; Gong, Sitang; Guo, Guoqing

    2015-01-01

    Cytoskeleton dynamics are critical phenomena that underpin many fundamental cellular processes. Collapsin response mediator proteins (CRMPs) are highly expressed in the developing nervous system, mediating growth cone guidance, neuronal polarity, and axonal elongation. However, whether and how CRMPs associate with microtubules and actin coordinated cytoskeletal dynamics remain unknown. In this study, we demonstrated that CRMP2 and CRMP4 interacted with tubulin and actin in vitro and colocalized with the cytoskeleton in the transition-zone in developing growth cones. CRMP2 and CRMP4 also interacted with one another coordinately to promote growth cone development and axonal elongation. Genetic silencing of CRMP2 enhanced, whereas overexpression of CRMP2 suppressed, the inhibitory effects of CRMP4 knockdown on axonal development. In addition, knockdown of CRMP2 or overexpression of truncated CRMP2 reversed the promoting effect of CRMP4. With the overexpression of truncated CRMP2 or CRMP4 lacking the cytoskeleton interaction domain, the promoting effect of CRMP was suppressed. These data suggest a model in which CRMP2 and CRMP4 form complexes to bridge microtubules and actin and thus work cooperatively to regulate growth cone development and axonal elongation.

  10. Coordination in the dynamics of the brain as inferred from EEG analysis.

    PubMed

    Pravitha, R; Nampoori, V P N

    2002-10-01

    The present study observed the coordination between cortical areas during no task conditions as well as for the pathological condition of epilepsy, by application of the phase synchronization technique to the EEG signal in a multichannel recording. The index obtained from the phase entrainment investigation was properly scaled by a novel method to take into account the effect of nearest neighbor interactions. This scaled index was analyzed temporally to learn about the behavior of regional interactions in time. The results obtained not only corroborate earlier known results, but also give deeper insight into actual brain functioning. PMID:12587525

  11. Measurement of dynamic stereoacuity and global stereopsis.

    PubMed

    Dunlop, D B; Neill, R A; Dunlop, P

    1980-02-01

    Quantification of global stereopsis in addition to stereoacuity has been achieved by using dynamic random dot test patterns generated by inexpensive computer controlled integrated electronics. A pilot study revealed marked differences between the responses of a variety of clinically defective and normal subjects.

  12. Penta- and hexa-coordinate ferric hemoglobins display distinct pH titration profiles measured by Soret peak shifts.

    PubMed

    Uppal, Sheetal; Kumar, Amit; Shandilya, Manish; Mukhi, Nitika; Singh, Amit Kumar; Kateriya, Suneel; Kaur, Jagreet; Kundu, Suman

    2016-10-01

    Hemoglobins with diverse characteristics have been identified in all kingdoms of life. Their ubiquitous presence indicates that these proteins play important roles in physiology, though function for all hemoglobins are not yet established with certainty. Their physiological role may depend on their ability to bind ligands, which in turn is dictated by their heme chemistry. However, we have an incomplete understanding of the mechanism of ligand binding for these newly discovered hemoglobins and the measurement of their kinetic parameters depend on their coordination at the heme iron. To gain insights into their functional role, it is important to categorize the new hemoglobins into either penta- or hexa-coordinated varieties. We demonstrate that simple pH titration and absorbance measurements can determine the coordination state of heme iron atom in ferric hemoglobins, thus providing unambiguous information about the classification of new globins. This method is rapid, sensitive and requires low concentration of protein. Penta- and hexa-coordinate hemoglobins displayed distinct pH titration profiles as observed in a variety of hemoglobins. The pentacoordinate distal histidine mutant proteins of hexacoordinate hemoglobins and ligand-bound hexacoordinate forms of pentacoordinate hemoglobins reverse the pH titration profiles, thus validating the sensitivity of this spectroscopic technique.

  13. Penta- and hexa-coordinate ferric hemoglobins display distinct pH titration profiles measured by Soret peak shifts.

    PubMed

    Uppal, Sheetal; Kumar, Amit; Shandilya, Manish; Mukhi, Nitika; Singh, Amit Kumar; Kateriya, Suneel; Kaur, Jagreet; Kundu, Suman

    2016-10-01

    Hemoglobins with diverse characteristics have been identified in all kingdoms of life. Their ubiquitous presence indicates that these proteins play important roles in physiology, though function for all hemoglobins are not yet established with certainty. Their physiological role may depend on their ability to bind ligands, which in turn is dictated by their heme chemistry. However, we have an incomplete understanding of the mechanism of ligand binding for these newly discovered hemoglobins and the measurement of their kinetic parameters depend on their coordination at the heme iron. To gain insights into their functional role, it is important to categorize the new hemoglobins into either penta- or hexa-coordinated varieties. We demonstrate that simple pH titration and absorbance measurements can determine the coordination state of heme iron atom in ferric hemoglobins, thus providing unambiguous information about the classification of new globins. This method is rapid, sensitive and requires low concentration of protein. Penta- and hexa-coordinate hemoglobins displayed distinct pH titration profiles as observed in a variety of hemoglobins. The pentacoordinate distal histidine mutant proteins of hexacoordinate hemoglobins and ligand-bound hexacoordinate forms of pentacoordinate hemoglobins reverse the pH titration profiles, thus validating the sensitivity of this spectroscopic technique. PMID:27449132

  14. Coordinate Regulation of G Protein Signaling via Dynamic Interactions of Receptor and GAP

    PubMed Central

    Turcotte, Marc; Tang, Wei; Ross, Elliott M.

    2008-01-01

    Signal output from receptor–G-protein–effector modules is a dynamic function of the nucleotide exchange activity of the receptor, the GTPase-accelerating activity of GTPase-activating proteins (GAPs), and their interactions. GAPs may inhibit steady-state signaling but may also accelerate deactivation upon removal of stimulus without significantly inhibiting output when the receptor is active. Further, some effectors (e.g., phospholipase C-β) are themselves GAPs, and it is unclear how such effectors can be stimulated by G proteins at the same time as they accelerate G protein deactivation. The multiple combinations of protein–protein associations and interacting regulatory effects that allow such complex behaviors in this system do not permit the usual simplifying assumptions of traditional enzyme kinetics and are uniquely subject to systems-level analysis. We developed a kinetic model for G protein signaling that permits analysis of both interactive and independent G protein binding and regulation by receptor and GAP. We evaluated parameters of the model (all forward and reverse rate constants) by global least-squares fitting to a diverse set of steady-state GTPase measurements in an m1 muscarinic receptor–Gq–phospholipase C-β1 module in which GTPase activities were varied by ∼104-fold. We provide multiple tests to validate the fitted parameter set, which is consistent with results from the few previous pre-steady-state kinetic measurements. Results indicate that (1) GAP potentiates the GDP/GTP exchange activity of the receptor, an activity never before reported; (2) exchange activity of the receptor is biased toward replacement of GDP by GTP; (3) receptor and GAP bind G protein with negative cooperativity when G protein is bound to either GTP or GDP, promoting rapid GAP binding and dissociation; (4) GAP indirectly stabilizes the continuous binding of receptor to G protein during steady-state GTPase hydrolysis, thus further enhancing receptor activity

  15. Coordinated Observations of X-ray and High-resolution EUV Active Region Dynamics

    NASA Technical Reports Server (NTRS)

    Savage, Sabrina

    2013-01-01

    The recently-launched High-resolution Coronal imager (Hi-C) sounding rocket provided the highest resolution images of coronal loops and other small-scale structures in the 193 Angstrom passband to date. With just 5 minutes of observations, the instrument recorded a variety of dynamic coronal events -- including even a small B-class flare. We will present our results comparing these extreme-ultraviolet (EUV) observations with X-ray imaging from Hinode/XRT as well as EUV AIA data to identify sources of hot plasma rooted in the photosphere and track their affect on the overall topology and dynamics of the active region.

  16. Coordinated Observations of X-ray and High-Resolution EUV Active Region Dynamics

    NASA Technical Reports Server (NTRS)

    Savage, Sabrina; Cirtain, Jonathan; Winebarger, Amy; Kobayashi, Ken; Golub, Leon; Korreck, Kelly

    2013-01-01

    The recently-launched High-resolution Coronal imager (Hi-C) sounding rocket provided the highest resolution images of coronal loops and other small-scale structures in the 193 Angstrom passband to date. With just 5 minutes of observations, the instrument recorded a variety of dynamic coronal events -- including even a small B-class flare. We will present our results comparing these extreme-ultraviolet (EUV) observations with X-ray imaging from Hinode/XRT as well as EUV AIA data to identify sources of hot plasma rooted in the photosphere and track their affect on the overall topology and dynamics of the active region.

  17. Numbers and Measuring, Learning With TOR: MINNEMAST Coordinated Mathematics - Science Series, Unit 16.

    ERIC Educational Resources Information Center

    Vogt, Elaine E., Ed.

    This volume is the sixteenth in a series of 29 coordinated MINNEMAST units in mathematics and science for kindergarten and the primary grades. Intended for use by second-grade teachers, this unit guide provides a summary and overview of the unit, a list of materials needed, and descriptions of five groups of lessons. The purposes and procedures…

  18. Stable reduced-order models of generalized dynamical systems using coordinate-transformed Arnoldi algorithms

    SciTech Connect

    Silveira, L.M.; Kamon, M.; Elfadel, I.; White, J.

    1996-12-31

    Model order reduction based on Krylov subspace iterative methods has recently emerged as a major tool for compressing the number of states in linear models used for simulating very large physical systems (VLSI circuits, electromagnetic interactions). There are currently two main methods for accomplishing such a compression: one is based on the nonsymmetric look-ahead Lanczos algorithm that gives a numerically stable procedure for finding Pade approximations, while the other is based on a less well characterized Arnoldi algorithm. In this paper, we show that for certain classes of generalized state-space systems, the reduced-order models produced by a coordinate-transformed Arnoldi algorithm inherit the stability of the original system. Complete Proofs of our results will be given in the final paper.

  19. Coordinated Approaches to Quantify Long-Term Ecosystem dynamics in Response to Global Change

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Climate change and its impact on ecosystems are usually assessed at decadal and century time scales. Ecological responses to climate change at those scales are strongly regulated by long-term processes, such as changes in species composition, carbon dynamics in soil and by big trees, and nutrient r...

  20. Effects of coordinate system choice on measured regional myocardial function in short axis cine electron-beam tomography

    SciTech Connect

    Reed, J.; Rumberger, J.; Buithieu, J.; Behrenbeck, T.; Breen, J.; Sheedy, P. II

    1995-12-31

    Following myocardial infarction, the size of the infarcted region and the systolic functioning of the non-infarcted region are commonly assessed by various cross-sectional imaging techniques. For the assessment of patterns of ventricular contraction, images are commonly acquired of ventricular cross-sections normal to the long axis of the heart and parallel to the mitral valve plane. The endocardial and epicardial surfaces of the myocardium are identified. Then the ventricle is divided into sectors and the volumes of blood and myocardium within each sector at multiple phases of the cardiac cycle are measured. Regional function parameters are derived from these measurements. This generally mandates the use of a polar or cylindrical coordinate system. Various algorithms have been used to select the origin of this coordinate system. These include the centroid of the endocardial surface, the epicardial surface, or of a polygon whose vertices lie midway between the epicardial and endocardial surfaces of the myocardium (centerline method). Another algorithm has been developed in the laboratory. This uses the centroid (or center of mass) of the myocardium exclusive of the ventricular cavity.Each of these choices for origin of coordinate system can be derived from the end-diastolic image or from the end-systolic image. Alternately, new coordinate system can be selected for each phase of the cardiac cycle. These are referred to as floating coordinate systems. A series of computer models have been developed in the laboratory to study the effects of each of these choices on the regional function parameters of normal ventricles and how these choices effect the quantification of regional abnormalities after myocardial infarction.

  1. Evaluation of a dual beam laser Doppler displacement meter retrofitted to a coordinate measuring machine. Final report

    SciTech Connect

    Ramsdale, S.J.; Hanshaw, R.A.

    1997-05-01

    A dual beam laser Doppler displacement measuring system was mounted to a fixed-table, cantilever-type coordinate measuring machine (CMM) to establish the feasibility of real time angular error correction for each CMM axis. The performance improvement was evaluated relative to the CMM`s standard scales. The dual beam system proved to have no advantage over a single beam laser due to an inability to measure the actual angular errors at the probe location, but showed potential for substantial accuracy improvement over the standard CMM scales when geometry errors were software corrected.

  2. Suppressing Respiration Effects when Geometric Distortion Is Corrected Dynamically by Phase Labeling for Additional Coordinate Encoding (PLACE) during Functional MRI.

    PubMed

    Faraji-Dana, Zahra; Tam, Fred; Chen, J Jean; Graham, Simon J

    2016-01-01

    Echo planar imaging (EPI) suffers from geometric distortions caused by magnetic field inhomogeneities, which can be time-varying as a result of small amounts of head motion that occur over seconds and minutes during fMRI experiments, also known as "dynamic geometric distortion". Phase Labeling for Additional Coordinate Encoding (PLACE) is a promising technique for geometric distortion correction without reduced temporal resolution and in principle can be used to correct for motion-induced dynamic geometric distortion. PLACE requires at least two EPI images of the same anatomy that are ideally acquired with no variation in the magnetic field inhomogeneities. However, head motion and lung ventilation during the respiratory cycle can cause changes in magnetic field inhomogeneities within the EPI pair used for PLACE. In this work, we exploited dynamic off-resonance in k-space (DORK) and averaging to correct the within EPI pair magnetic field inhomogeneities; and hence proposed a combined technique (DORK+PLACE+averaging) to mitigate dynamic geometric distortion in EPI-based fMRI while preserving the temporal resolution. The performance of the combined DORK, PLACE and averaging technique was characterized through several imaging experiments involving test phantoms and six healthy adult volunteers. Phantom data illustrate reduced temporal standard deviation of fMRI signal intensities after use of combined dynamic PLACE, DORK and averaging compared to the standard processing and static geometric distortion correction. The combined technique also substantially improved the temporal standard deviation and activation maps obtained from human fMRI data in comparison to the results obtained by standard processing and static geometric distortion correction, highlighting the utility of the approach. PMID:27258194

  3. Suppressing Respiration Effects when Geometric Distortion Is Corrected Dynamically by Phase Labeling for Additional Coordinate Encoding (PLACE) during Functional MRI

    PubMed Central

    Faraji-Dana, Zahra; Tam, Fred; Chen, J. Jean; Graham, Simon J.

    2016-01-01

    Echo planar imaging (EPI) suffers from geometric distortions caused by magnetic field inhomogeneities, which can be time-varying as a result of small amounts of head motion that occur over seconds and minutes during fMRI experiments, also known as “dynamic geometric distortion”. Phase Labeling for Additional Coordinate Encoding (PLACE) is a promising technique for geometric distortion correction without reduced temporal resolution and in principle can be used to correct for motion-induced dynamic geometric distortion. PLACE requires at least two EPI images of the same anatomy that are ideally acquired with no variation in the magnetic field inhomogeneities. However, head motion and lung ventilation during the respiratory cycle can cause changes in magnetic field inhomogeneities within the EPI pair used for PLACE. In this work, we exploited dynamic off-resonance in k-space (DORK) and averaging to correct the within EPI pair magnetic field inhomogeneities; and hence proposed a combined technique (DORK+PLACE+averaging) to mitigate dynamic geometric distortion in EPI-based fMRI while preserving the temporal resolution. The performance of the combined DORK, PLACE and averaging technique was characterized through several imaging experiments involving test phantoms and six healthy adult volunteers. Phantom data illustrate reduced temporal standard deviation of fMRI signal intensities after use of combined dynamic PLACE, DORK and averaging compared to the standard processing and static geometric distortion correction. The combined technique also substantially improved the temporal standard deviation and activation maps obtained from human fMRI data in comparison to the results obtained by standard processing and static geometric distortion correction, highlighting the utility of the approach. PMID:27258194

  4. Modelling and calibration technique of laser triangulation sensors for integration in robot arms and articulated arm coordinate measuring machines.

    PubMed

    Santolaria, Jorge; Guillomía, David; Cajal, Carlos; Albajez, José A; Aguilar, Juan J

    2009-01-01

    A technique for intrinsic and extrinsic calibration of a laser triangulation sensor (LTS) integrated in an articulated arm coordinate measuring machine (AACMM) is presented in this paper. After applying a novel approach to the AACMM kinematic parameter identification problem, by means of a single calibration gauge object, a one-step calibration method to obtain both intrinsic-laser plane, CCD sensor and camera geometry-and extrinsic parameters related to the AACMM main frame has been developed. This allows the integration of LTS and AACMM mathematical models without the need of additional optimization methods after the prior sensor calibration, usually done in a coordinate measuring machine (CMM) before the assembly of the sensor in the arm. The experimental tests results for accuracy and repeatability show the suitable performance of this technique, resulting in a reliable, quick and friendly calibration method for the AACMM final user. The presented method is also valid for sensor integration in robot arms and CMMs.

  5. Modelling and calibration technique of laser triangulation sensors for integration in robot arms and articulated arm coordinate measuring machines.

    PubMed

    Santolaria, Jorge; Guillomía, David; Cajal, Carlos; Albajez, José A; Aguilar, Juan J

    2009-01-01

    A technique for intrinsic and extrinsic calibration of a laser triangulation sensor (LTS) integrated in an articulated arm coordinate measuring machine (AACMM) is presented in this paper. After applying a novel approach to the AACMM kinematic parameter identification problem, by means of a single calibration gauge object, a one-step calibration method to obtain both intrinsic-laser plane, CCD sensor and camera geometry-and extrinsic parameters related to the AACMM main frame has been developed. This allows the integration of LTS and AACMM mathematical models without the need of additional optimization methods after the prior sensor calibration, usually done in a coordinate measuring machine (CMM) before the assembly of the sensor in the arm. The experimental tests results for accuracy and repeatability show the suitable performance of this technique, resulting in a reliable, quick and friendly calibration method for the AACMM final user. The presented method is also valid for sensor integration in robot arms and CMMs. PMID:22400001

  6. Modelling and Calibration Technique of Laser Triangulation Sensors for Integration in Robot Arms and Articulated Arm Coordinate Measuring Machines

    PubMed Central

    Santolaria, Jorge; Guillomía, David; Cajal, Carlos; Albajez, José A.; Aguilar, Juan J.

    2009-01-01

    A technique for intrinsic and extrinsic calibration of a laser triangulation sensor (LTS) integrated in an articulated arm coordinate measuring machine (AACMM) is presented in this paper. After applying a novel approach to the AACMM kinematic parameter identification problem, by means of a single calibration gauge object, a one-step calibration method to obtain both intrinsic—laser plane, CCD sensor and camera geometry—and extrinsic parameters related to the AACMM main frame has been developed. This allows the integration of LTS and AACMM mathematical models without the need of additional optimization methods after the prior sensor calibration, usually done in a coordinate measuring machine (CMM) before the assembly of the sensor in the arm. The experimental tests results for accuracy and repeatability show the suitable performance of this technique, resulting in a reliable, quick and friendly calibration method for the AACMM final user. The presented method is also valid for sensor integration in robot arms and CMMs. PMID:22400001

  7. Leading-process actomyosin coordinates organelle positioning and adhesion receptor dynamics in radially migrating cerebellar granule neurons

    SciTech Connect

    Trivedi, Niraj; Ramahi, Joseph S.; Karakaya, Mahmut; Howell, Danielle; Kerekes, Ryan A.; Solecki, David J.

    2014-12-02

    During brain development, neurons migrate from germinal zones to their final positions to assemble neural circuits. A unique saltatory cadence involving cyclical organelle movement (e.g., centrosome motility) and leading-process actomyosin enrichment prior to nucleokinesis organizes neuronal migration. While functional evidence suggests that leading-process actomyosin is essential for centrosome motility, the role of the actin-enriched leading process in globally organizing organelle transport or traction forces remains unexplored. Our results show that myosin ii motors and F-actin dynamics are required for Golgi apparatus positioning before nucleokinesis in cerebellar granule neurons (CGNs) migrating along glial fibers. Moreover, we show that primary cilia are motile organelles, localized to the leading-process F-actin-rich domain and immobilized by pharmacological inhibition of myosin ii and F-actin dynamics. Finally, leading process adhesion dynamics are dependent on myosin ii and F-actin. In conclusion, we propose that actomyosin coordinates the overall polarity of migrating CGNs by controlling asymmetric organelle positioning and cell-cell contacts as these cells move along their glial guides.

  8. Leading-process actomyosin coordinates organelle positioning and adhesion receptor dynamics in radially migrating cerebellar granule neurons

    DOE PAGES

    Trivedi, Niraj; Ramahi, Joseph S.; Karakaya, Mahmut; Howell, Danielle; Kerekes, Ryan A.; Solecki, David J.

    2014-12-02

    During brain development, neurons migrate from germinal zones to their final positions to assemble neural circuits. A unique saltatory cadence involving cyclical organelle movement (e.g., centrosome motility) and leading-process actomyosin enrichment prior to nucleokinesis organizes neuronal migration. While functional evidence suggests that leading-process actomyosin is essential for centrosome motility, the role of the actin-enriched leading process in globally organizing organelle transport or traction forces remains unexplored. Our results show that myosin ii motors and F-actin dynamics are required for Golgi apparatus positioning before nucleokinesis in cerebellar granule neurons (CGNs) migrating along glial fibers. Moreover, we show that primary cilia aremore » motile organelles, localized to the leading-process F-actin-rich domain and immobilized by pharmacological inhibition of myosin ii and F-actin dynamics. Finally, leading process adhesion dynamics are dependent on myosin ii and F-actin. In conclusion, we propose that actomyosin coordinates the overall polarity of migrating CGNs by controlling asymmetric organelle positioning and cell-cell contacts as these cells move along their glial guides.« less

  9. Coordinated Global Measurements of TLEs from the Space Shuttle and Ground Stations during MEIDEX

    NASA Astrophysics Data System (ADS)

    Yair, Y.; Price, C.; Levin, Z.; Israelevitch, P.; Devir, A.; Ziv, B.; Jospeh, J.; Mekler, Y.

    2001-12-01

    in the crew cabin. Simultaneously with the optical observations from space, dedicated ground measurements will be conducted on a global scale. Two field sites in the Negev Desert in Israel will be used to collect electromagnetic data in the ELF and VLF frequency range. Additional ground stations in Germany, Hungary, USA, Antarctica, Chile, South Africa, Australia, Taiwan and Japan will also record Schumann Resonance and VLF signals. The coordinated measurements from various locations on Earth and from space will enable us to triangulate the location, and determine the polarity and charge moment of the parent lightning of the optically observed TLEs. The success of the campaign will further clarify the global picture of TLE occurrence.

  10. Using Mean Absolute Relative Phase, Deviation Phase and Point-Estimation Relative Phase to Measure Postural Coordination in a Serial Reaching Task.

    PubMed

    Galgon, Anne K; Shewokis, Patricia A

    2016-03-01

    The objectives of this communication are to present the methods used to calculate mean absolute relative phase (MARP), deviation phase (DP) and point estimate relative phase (PRP) and compare their utility in measuring postural coordination during the performance of a serial reaching task. MARP and DP are derived from continuous relative phase time series representing the relationship between two body segments or joints during movements. MARP is a single measure used to quantify the coordination pattern and DP measures the stability of the coordination pattern. PRP also quantifies coordination patterns by measuring the relationship between the timing of maximal or minimal angular displacements of two segments within cycles of movement. Seven young adults practiced a bilateral serial reaching task 300 times over 3 days. Relative phase measures were used to evaluate inter-joint relationships for shoulder-hip (proximal) and hip-ankle (distal) postural coordination at early and late learning. MARP, PRP and DP distinguished between proximal and distal postural coordination. There was no effect of practice on any of the relative phase measures for the group, but individual differences were seen over practice. Combined, MARP and DP estimated stability of in-phase and anti-phase postural coordination patterns, however additional qualitative movement analyses may be needed to interpret findings in a serial task. We discuss the strengths and limitations of using MARP and DP and compare MARP and DP to PRP measures in assessing coordination patterns in the context of various types of skillful tasks. Key pointsMARP, DP and PRP measures coordination between segments or joint anglesAdvantages and disadvantages of each measure should be considered in relationship to the performance taskMARP and DP may capture coordination patterns and stability of the patterns during discrete tasks or phases of movements within a taskPRP and SD or PRP may capture coordination patterns and

  11. Measured Spacecraft Dynamic Effects on Atmospheric Science Instruments

    NASA Technical Reports Server (NTRS)

    Woodard, Stanley E.; Gell, David A.; Lay, Richard R.

    1997-01-01

    On September 1991, NASA launched the Upper Atmosphere Research Satellite. In addition to its atmospheric science mission, spacecraft dynamic effects on science measurements were analyzed. The investigation included two in-flight experiments to determine how each on-board instrument, subsystem and environmental disturbance contributed to the spacecraft dynamic response and how these disturbances affected science measurements. Three case studies are presented which show the impact of spacecraft dynamic response on science measurements. In the first case, correlation of independent atmospheric meridional wind measurements taken by two instruments with the spacecraft dynamic response demonstrated that excessive vibration (exceeding instrument pointing requirements) resulted in wind measurement disagreement. In the second case, solar array disturbances produced a spacecraft response signature on radiometer measurements. The signature explicitly demonstrated that if an instrument has sufficient spatial and temporal resolution, spacecraft dynamic response could impact measurements. In the final case, correlation of an instrument's fine sun sensor data and CO2 measurements demonstrated the effect of temporal and spatial sampling resolution and active pointing control on science measurements. The sun sensor had a frequency modulated characteristic due to spacecraft vibration and the periodic scanning of another instrument which was not present on the CO2 measurements.

  12. CO2 selective dynamic two-dimensional Zn(II) coordination polymer.

    PubMed

    Hwang, In Hong; Bae, Jeong Mi; Hwang, Yong-Kyung; Kim, Ha-Yeong; Kim, Cheal; Huh, Seong; Kim, Sung-Jin; Kim, Youngmee

    2013-11-28

    A CO2 selective dynamic two-dimensional (2D) MOF system, [Zn(glu)(μ-bpe)]·2H2O (·2H2O) (glu = glutarate, bpe = 1,2-bis(4-pyridyl)ethylene), is prepared. Based on variable temperature PXRD patterns, I·2H2O exhibits a structural transformation of the framework upon desolvation. Various gas sorption analyses at low temperatures reveal that solvent-free I selectively adsorbs CO2 over N2, H2, and CH4. Stepped CO2 isotherms for solvent-free I with a large hysteresis between adsorption and desorption branches at 196 K indicate that I is a dynamic framework. Moreover, I·2H2O shows efficient heterogeneous catalytic reactivity for transesterification of various esters. The catalyst can be recycled multiple times without losing its original activity.

  13. GUI for Coordinate Measurement of an Image for the Estimation of Geometric Distortion of an Opto-electronic Display System

    NASA Astrophysics Data System (ADS)

    Saini, Surender Singh; Sardana, Harish Kumar; Pattnaik, Shyam Sundar

    2016-07-01

    Conventional image editing software in combination with other techniques are not only difficult to apply to an image but also permits a user to perform some basic functions one at a time. However, image processing algorithms and photogrammetric systems are developed in the recent past for real-time pattern recognition applications. A graphical user interface (GUI) is developed which can perform multiple functions simultaneously for the analysis and estimation of geometric distortion in an image with reference to the corresponding distorted image. The GUI measure, record, and visualize the performance metric of X/Y coordinates of one image over the other. The various keys and icons provided in the utility extracts the coordinates of distortion free reference image and the image with geometric distortion. The error between these two corresponding points gives the measure of distortion and also used to evaluate the correction parameters for image distortion. As the GUI interface minimizes human interference in the process of geometric correction, its execution just requires use of icons and keys provided in the utility; this technique gives swift and accurate results as compared to other conventional methods for the measurement of the X/Y coordinates of an image.

  14. Coordinate control of terminal dendrite patterning and dynamics by the membrane protein Raw

    PubMed Central

    Lee, Jiae; Peng, Yun; Lin, Wen-Yang; Parrish, Jay Z.

    2015-01-01

    The directional flow of information in neurons depends on compartmentalization: dendrites receive inputs whereas axons transmit them. Axons and dendrites likewise contain structurally and functionally distinct subcompartments. Axon/dendrite compartmentalization can be attributed to neuronal polarization, but the developmental origin of subcompartments in axons and dendrites is less well understood. To identify the developmental bases for compartment-specific patterning in dendrites, we screened for mutations that affect discrete dendritic domains in Drosophila sensory neurons. From this screen, we identified mutations that affected distinct aspects of terminal dendrite development with little or no effect on major dendrite patterning. Mutation of one gene, raw, affected multiple aspects of terminal dendrite patterning, suggesting that Raw might coordinate multiple signaling pathways to shape terminal dendrite growth. Consistent with this notion, Raw localizes to branch-points and promotes dendrite stabilization together with the Tricornered (Trc) kinase via effects on cell adhesion. Raw independently influences terminal dendrite elongation through a mechanism that involves modulation of the cytoskeleton, and this pathway is likely to involve the RNA-binding protein Argonaute 1 (AGO1), as raw and AGO1 genetically interact to promote terminal dendrite growth but not adhesion. Thus, Raw defines a potential point of convergence in distinct pathways shaping terminal dendrite patterning. PMID:25480915

  15. The dynamics of coordinated group hunting and collective information transfer among schooling prey.

    PubMed

    Handegard, Nils Olav; Boswell, Kevin M; Ioannou, Christos C; Leblanc, Simon P; Tjøstheim, Dag B; Couzin, Iain D

    2012-07-10

    Predator-prey interactions are vital to the stability of many ecosystems. Yet, few studies have considered how they are mediated due to substantial challenges in quantifying behavior over appropriate temporal and spatial scales. Here, we employ high-resolution sonar imaging to track the motion and interactions among predatory fish and their schooling prey in a natural environment. In particular, we address the relationship between predator attack behavior and the capacity for prey to respond both directly and through collective propagation of changes in velocity by group members. To do so, we investigated a large number of attacks and estimated per capita risk during attack and its relation to the size, shape, and internal structure of prey groups. Predators were found to frequently form coordinated hunting groups, with up to five individuals attacking in line formation. Attacks were associated with increased fragmentation and irregularities in the spatial structure of prey groups, features that inhibit collective information transfer among prey. Prey group fragmentation, likely facilitated by predator line formation, increased (estimated) per capita risk of prey, provided prey schools were maintained below a threshold size of approximately 2 m(2). Our results highlight the importance of collective behavior to the strategies employed by both predators and prey under conditions of considerable informational constraints.

  16. Conductance measurement circuit with wide dynamic range

    NASA Technical Reports Server (NTRS)

    Mount, Bruce E. (Inventor); Von Esch, Myron (Inventor)

    1994-01-01

    A conductance measurement circuit to measure conductance of a solution under test with an output voltage proportional to conductance over a 5-decade range, i.e., 0.01 uS to 1000 uS or from 0.1 uS to 10,000 uS. An increase in conductance indicates growth, or multiplication, of the bacteria in the test solution. Two circuits are used each for an alternate half-cycle time periods of an alternate squarewave in order to cause alternate and opposite currents to be applied to the test solution. The output of one of the two circuits may be scaled for a different range optimum switching frequency dependent upon the solution conductance and to enable uninterrupted measurement over the complete 5-decade range. This circuitry provides two overlapping ranges of conductance which can be read simultaneously without discontinuity thereby eliminating range switching within the basic circuitry. A VCO is used to automatically change the operating frequency according to the particular value of the conductance being measured, and comparators indicate which range is valid and also facilitate computer-controlled data acquisition. A multiplexer may be used to monitor any number of solutions under test continuously.

  17. Probing-error compensation using 5 degree of freedom force/moment sensor for coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Lee, Minho; Cho, Nahm-Gyoo

    2013-09-01

    A new probing and compensation method is proposed to improve the three-dimensional (3D) measuring accuracy of 3D shapes, including irregular surfaces. A new tactile coordinate measuring machine (CMM) probe with a five-degree of freedom (5-DOF) force/moment sensor using carbon fiber plates was developed. The proposed method efficiently removes the anisotropic sensitivity error and decreases the stylus deformation and the actual contact point estimation errors that are major error components of shape measurement using touch probes. The relationship between the measuring force and estimation accuracy of the actual contact point error and stylus deformation error are examined for practical use of the proposed method. The appropriate measuring force condition is presented for the precision measurement.

  18. Localized measurements of composite dynamic response for health monitoring

    NASA Astrophysics Data System (ADS)

    Webb, Sean; Oman, Kyle; Peters, Kara; Stan, Nikola; Chadderdon, Spencer; Selfridge, Richard; Schultz, Stephen

    2014-04-01

    We demonstrate the measurement of and applications for full-spectral measurements collected from FBG sensors in dynamic loading environments. The measurement of the dynamic response of a laminated plate to an impact event highlights the information gained during the event as compared to after the event. The measurement of damage induced spectral distortion in a thin plate during vibration loading demonstrates the capability of separating spectral distortion due to multiple effects, including damage and vibration loading. Finally, the measurement of the change in dynamic response of an adhesively bonded joint highlights the capability to measure the progression of fatigue damage. Confirmation that the change in FBG response is due to fatigue damage is performed through independent pulsed phase thermography imaging of the adhesively bonded joint.

  19. Connection and coordination: the interplay between architecture and dynamics in evolved model pattern generators.

    PubMed

    Psujek, Sean; Ames, Jeffrey; Beer, Randall D

    2006-03-01

    We undertake a systematic study of the role of neural architecture in shaping the dynamics of evolved model pattern generators for a walking task. First, we consider the minimum number of connections necessary to achieve high performance on this task. Next, we identify architectural motifs associated with high fitness. We then examine how high-fitness architectures differ in their ability to evolve. Finally, we demonstrate the existence of distinct parameter subgroups in some architectures and show that these subgroups are characterized by differences in neuron excitabilities and connection signs. PMID:16483415

  20. Incomplete fusion dynamics by spin distribution measurements

    SciTech Connect

    Singh, D.; Ali, R.; Ansari, M. Afzal; Singh, Pushpendra P.; Sharma, M. K.; Singh, B. P.; Babu, K. Surendra; Sinha, Rishi K.; Kumar, R.; Muralithar, S.; Singh, R. P.; Bhowmik, R. K.

    2010-02-15

    Spin distributions for various evaporation residues populated via complete and incomplete fusion of {sup 16}O with {sup 124}Sn at 6.3 MeV/nucleon have been measured, using charged particles (Z=1,2)-{gamma} coincidence technique. Experimentally measured spin distributions of the residues produced as incomplete fusion products associated with 'fast'{alpha}- and 2{alpha}-emission channels observed in the 'forward cone' are found to be distinctly different from those of the residues produced as complete fusion products. Moreover, 'fast'{alpha}-particles that arise from larger angular momentum in the entrance channel are populated at relatively higher driving input angular momentum than those produced through complete fusion. The incomplete fusion residues are populated in a limited, higher-angular-momentum range, in contrast to the complete fusion products, which are populated over a broad spin range.

  1. A program for performing exact quantum dynamics calculations using cylindrical polar coordinates: A nanotube application

    NASA Astrophysics Data System (ADS)

    Skouteris, Dimitris; Gervasi, Osvaldo; Laganà, Antonio

    2009-03-01

    A program that uses the time-dependent wavepacket method to study the motion of structureless particles in a force field of quasi-cylindrical symmetry is presented here. The program utilises cylindrical polar coordinates to express the wavepacket, which is subsequently propagated using a Chebyshev expansion of the Schrödinger propagator. Time-dependent exit flux as well as energy-dependent S matrix elements can be obtained for all states of the particle (describing its angular momentum component along the nanotube axis and the excitation of the radial degree of freedom in the cylinder). The program has been used to study the motion of an H atom across a carbon nanotube. Program summaryProgram title: CYLWAVE Catalogue identifier: AECL_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AECL_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 3673 No. of bytes in distributed program, including test data, etc.: 35 237 Distribution format: tar.gz Programming language: Fortran 77 Computer: RISC workstations Operating system: UNIX RAM: 120 MBytes Classification: 16.7, 16.10 External routines: SUNSOFT performance library (not essential) TFFT2D.F (Temperton Fast Fourier Transform), BESSJ.F (from Numerical Recipes, for the calculation of Bessel functions) (included in the distribution file). Nature of problem: Time evolution of the state of a structureless particle in a quasicylindrical potential. Solution method: Time dependent wavepacket propagation. Running time: 50000 secs. The test run supplied with the distribution takes about 10 minutes to complete.

  2. Design and Mechanical Evaluation of a Capacitive Sensor-Based Indexed Platform for Verification of Portable Coordinate Measuring Instruments

    PubMed Central

    Avila, Agustín Brau; Mazo, Jorge Santolaria; Martín, Juan José Aguilar

    2014-01-01

    During the last years, the use of Portable Coordinate Measuring Machines (PCMMs) in industry has increased considerably, mostly due to their flexibility for accomplishing in-line measuring tasks as well as their reduced costs and operational advantages as compared to traditional coordinate measuring machines (CMMs). However, their operation has a significant drawback derived from the techniques applied in the verification and optimization procedures of their kinematic parameters. These techniques are based on the capture of data with the measuring instrument from a calibrated gauge object, fixed successively in various positions so that most of the instrument measuring volume is covered, which results in time-consuming, tedious and expensive verification procedures. In this work the mechanical design of an indexed metrology platform (IMP) is presented. The aim of the IMP is to increase the final accuracy and to radically simplify the calibration, identification and verification of geometrical parameter procedures of PCMMs. The IMP allows us to fix the calibrated gauge object and move the measuring instrument in such a way that it is possible to cover most of the instrument working volume, reducing the time and operator fatigue to carry out these types of procedures. PMID:24451458

  3. A measure of individual role in collective dynamics

    PubMed Central

    Klemm, Konstantin; Serrano, M. Ángeles; Eguíluz, Víctor M.; Miguel, Maxi San

    2012-01-01

    Identifying key players in collective dynamics remains a challenge in several research fields, from the efficient dissemination of ideas to drug target discovery in biomedical problems. The difficulty lies at several levels: how to single out the role of individual elements in such intermingled systems, or which is the best way to quantify their importance. Centrality measures describe a node's importance by its position in a network. The key issue obviated is that the contribution of a node to the collective behavior is not uniquely determined by the structure of the system but it is a result of the interplay between dynamics and network structure. We show that dynamical influence measures explicitly how strongly a node's dynamical state affects collective behavior. For critical spreading, dynamical influence targets nodes according to their spreading capabilities. For diffusive processes it quantifies how efficiently real systems may be controlled by manipulating a single node. PMID:22379597

  4. Van Allen Probe measurements of the electric drift E × B/B2 at Arecibo's L = 1.4 field line coordinate

    NASA Astrophysics Data System (ADS)

    Lejosne, Solène; Mozer, F. S.

    2016-07-01

    We have used electric and magnetic measurements by Van Allen Probe B from 2013 to 2014 to examine the equatorial electric drift E × B/B2 at one field line coordinate set to Arecibo's incoherent scatter radar location (L = 1.43). We report on departures from the traditional picture of corotational motion with the Earth in two ways: (1) the rotational angular speed is found to be 10% smaller than the rotational angular speed of the Earth, in agreement with previous works on plasmaspheric notches, and (2) the equatorial electric drift displays a dependence in magnetic local time, with a pattern consistent with the mapping of the Arecibo ionosphere dynamo electric fields along equipotential magnetic field lines. The electric fields due to the ionosphere dynamo are therefore expected to play a significant role when discussing, for instance, the structure and dynamics of the plasmasphere or the transport of trapped particles in the inner belt.

  5. Study of the technical feasibility of photogrammetry and coordinated measuring arms for the inspection of welded structures

    NASA Astrophysics Data System (ADS)

    Sánchez-Lasheras, F.; Fernández, R. I.; Cuesta, E.; Álvarez, B. J.; Martínez, S.

    2012-04-01

    The present paper studies the technical feasibility of Photogrammetry and Coordinate Measuring Arms (AACMM or CMA) for the geometrical inspection of welded pins used for the assembly of medium-sized sheetmetal structures. As a result of this evaluation it was found that the deviations (measurement recorded by the device minus the nominal value of the measurement) obtained by means of Photogrammetry and the CMA were equivalent. Moreover, the number of measurements found to be out of tolerance by both methods was statistically equivalent. According to our results both methods are feasible for performing the dimensional inspection of the position of the welded cylinders of the structure as they are able to distinguish measurements inside and outside of tolerance and are equally capable of detecting the data variance.

  6. Latin square three-dimensional ball plate (a practical approach to evaluation of coordinate measuring machine capability)

    SciTech Connect

    Jones, L.L.

    1981-10-01

    Electronic coordinate measuring machines (CMM) represent the state-of-the-art in automatic three-dimensional measuring equipment. Current techniques for determining measurement capability of CMM are complex. A Latin square three-dimensional ball plate has been developed to evaluate the measurement capability of a CMM in three dimensions. The unique allocation of tooling balls in an XYZ space permits data to be obtained that is balanced statistically and can be analyzed quickly by using the analysis of variance techniques for a Latin square experimental design. The analysis of this data is used to determine quantitative measures of the precision and systematic error of CMM in three dimensions and to identify sources of error in machine geometry. This ball plate currently is used to determine CMM capability and to identify source(s) of error in machine geometry. This device requires 70% less time than some conventional techniques to estimate CMM capability in three dimensions.

  7. Dynamic eye phantom for retinal oximetry measurements

    PubMed Central

    Lemaillet, Paul; Ramella-Roman, Jessica C.

    2009-01-01

    Measurements of oxygen saturation and flow in the retina can yield information about eye health and the onset of eye pathologies such as diabetic retinopathy. Recently, we developed a multiaperture camera that uses the division of the retinal image into several wavelength-sensitive subimages to compute retinal oxygen saturation. The calibration of such instruments is particularly difficult due to the layered structure of the eye and the lack of alternative measurement techniques. For this purpose, we realize an in vitro model of the human eye composed of a lens, the retina vessel, and three layers: the choroid, the retinal pigmented epithelium, and the sclera. The retinal vessel is modeled with a microtube connected to a micropump and a hemoglobin reservoir in a closed circulatory system. Hemoglobin oxygenation in the vessel could be altered using a reversible fuel cell. The sclera is represented by a Spectralon slab. The optical properties of the other layers are mimicked using titanium dioxide as a scatterer, ink as an absorber, and epoxy as a supporting structure. The optical thickness of each layer of the eye phantom is matched to each respective eye layer. PMID:20059246

  8. Dynamic eye phantom for retinal oximetry measurements

    NASA Astrophysics Data System (ADS)

    Lemaillet, Paul; Ramella-Roman, Jessica C.

    2009-11-01

    Measurements of oxygen saturation and flow in the retina can yield information about eye health and the onset of eye pathologies such as diabetic retinopathy. Recently, we developed a multiaperture camera that uses the division of the retinal image into several wavelength-sensitive subimages to compute retinal oxygen saturation. The calibration of such instruments is particularly difficult due to the layered structure of the eye and the lack of alternative measurement techniques. For this purpose, we realize an in vitro model of the human eye composed of a lens, the retina vessel, and three layers: the choroid, the retinal pigmented epithelium, and the sclera. The retinal vessel is modeled with a microtube connected to a micropump and a hemoglobin reservoir in a closed circulatory system. Hemoglobin oxygenation in the vessel could be altered using a reversible fuel cell. The sclera is represented by a Spectralon slab. The optical properties of the other layers are mimicked using titanium dioxide as a scatterer, ink as an absorber, and epoxy as a supporting structure. The optical thickness of each layer of the eye phantom is matched to each respective eye layer.

  9. Measuring and balancing dynamic unbalance of precision centrifuge

    NASA Astrophysics Data System (ADS)

    Yang, Yafei; Huo, Xin

    2008-10-01

    A precision centrifuge is used to test and calibrate accelerometer model parameters. Its dynamic unbalance may cause the perturbation of the centrifuge to deteriorate the test and calibration accuracy of an accelerometer. By analyzing the causes of dynamic unbalance, the influences on precision centrifuge from static unbalance and couple unbalance are developed. It is considered measuring and balancing of static unbalance is a key to resolving a dynamic unbalance problem of precision centrifuge with a disk in structure. Measuring means and calculating formulas of static unbalance amount are given, and balancing principle and method are provided. The correctness and effectiveness of this method are confirmed by experiments on a device under tuning, thereby the accurate and high-effective measuring and balancing method of dynamic unbalance of this precision centrifuge was provided.

  10. Dynamic gas temperature measurement system, volume 1

    NASA Technical Reports Server (NTRS)

    Elmore, D. L.; Robinson, W. W.; Watkins, W. B.

    1983-01-01

    A gas temperature measurement system with compensated frequency response of 1 kHz and capability to operate in the exhaust of a gas turbine engine combustor was developed. A review of available technologies which could attain this objective was done. The most promising method was identified as a two wire thermocouple, with a compensation method based on the responses of the two different diameter thermocouples to the fluctuating gas temperature field. In a detailed design of the probe, transient conduction effects were identified as significant. A compensation scheme was derived to include the effects of gas convection and wire conduction. The two wire thermocouple concept was tested in a laboratory burner exhaust to temperatures of about 3000 F and in a gas turbine engine to combustor exhaust temperatures of about 2400 F. Uncompensated and compensated waveforms and compensation spectra are presented.

  11. Emergence of Rich-Club Topology and Coordinated Dynamics in Development of Hippocampal Functional Networks In Vitro

    PubMed Central

    Charlesworth, Paul; Kitzbichler, Manfred G.; Paulsen, Ole

    2015-01-01

    Recent studies demonstrated that the anatomical network of the human brain shows a “rich-club” organization. This complex topological feature implies that highly connected regions, hubs of the large-scale brain network, are more densely interconnected with each other than expected by chance. Rich-club nodes were traversed by a majority of short paths between peripheral regions, underlining their potential importance for efficient global exchange of information between functionally specialized areas of the brain. Network hubs have also been described at the microscale of brain connectivity (so-called “hub neurons”). Their role in shaping synchronous dynamics and forming microcircuit wiring during development, however, is not yet fully understood. The present study aimed to investigate the role of hubs during network development, using multi-electrode arrays and functional connectivity analysis during spontaneous multi-unit activity (MUA) of dissociated primary mouse hippocampal neurons. Over the first 4 weeks in vitro, functional connectivity significantly increased in strength, density, and size, with mature networks demonstrating a robust modular and small-world topology. As expected by a “rich-get-richer” growth rule of network evolution, MUA graphs were found to form rich-clubs at an early stage in development (14 DIV). Later on, rich-club nodes were a consistent topological feature of MUA graphs, demonstrating high nodal strength, efficiency, and centrality. Rich-club nodes were also found to be crucial for MUA dynamics. They often served as broker of spontaneous activity flow, confirming that hub nodes and rich-clubs may play an important role in coordinating functional dynamics at the microcircuit level. PMID:25855164

  12. Dynamic engagement of human motion detectors across space-time coordinates.

    PubMed

    Neri, Peter

    2014-06-18

    Motion detection is a fundamental property of the visual system. The gold standard for studying and understanding this function is the motion energy model. This computational tool relies on spatiotemporally selective filters that capture the change in spatial position over time afforded by moving objects. Although the filters are defined in space-time, their human counterparts have never been studied in their native spatiotemporal space but rather in the corresponding frequency domain. When this frequency description is back-projected to spatiotemporal description, not all characteristics of the underlying process are retained, leaving open the possibility that important properties of human motion detection may have remained unexplored. We derived descriptors of motion detectors in native space-time, and discovered a large unexpected dynamic structure involving a >2× change in detector amplitude over the first ∼100 ms. This property is not predicted by the energy model, generalizes across the visual field, and is robust to adaptation; however, it is silenced by surround inhibition and is contrast dependent. We account for all results by extending the motion energy model to incorporate a small network that supports feedforward spread of activation along the motion trajectory via a simple gain-control circuit.

  13. Coordinated three-dimensional motion of the head and torso by dynamic neural networks.

    PubMed

    Kim, J; Hemami, H

    1998-01-01

    The problem of trajectory tracking control of a three dimensional (3D) model of the human upper torso and head is considered. The torso and the head are modeled as two rigid bodies connected at one point, and the Newton-Euler method is used to derive the nonlinear differential equations that govern the motion of the system. The two-link system is driven by six pairs of muscle like actuators that possess physiologically inspired alpha like and gamma like inputs, and spindle like and Golgi tendon organ like outputs. These outputs are utilized as reflex feedback for stability and stiffness control, in a long loop feedback for the purpose of estimating the state of the system (somesthesis), and as part of the input to the controller. Ideal delays of different duration are included in the feedforward and feedback paths of the system to emulate such delays encountered in physiological systems. Dynamical neural networks are trained to learn effective control of the desired maneuvers of the system. The feasibility of the controller is demonstrated by computer simulation of the successful execution of the desired maneuvers. This work demonstrates the capabilities of neural circuits in controlling highly nonlinear systems with multidelays in their feedforward and feedback paths. The ultimate long range goal of this research is toward understanding the working of the central nervous system in controlling movement. It is an interdisciplinary effort relying on mechanics, biomechanics, neuroscience, system theory, physiology and anatomy, and its short range relevance to rehabilitation must be noted. PMID:18255985

  14. Slow dynamics of the magnetization in one-dimensional coordination polymers: single-chain magnets.

    PubMed

    Miyasaka, Hitoshi; Julve, Miguel; Yamashita, Masahiro; Clérac, Rodolphe

    2009-04-20

    Slow relaxation of the magnetization (i.e., "magnet-like" behavior) in materials composed of magnetically isolated chains was observed for the first time in 2001. This type of behavior was predicted in the 1960s by Glauber in a chain of ferromagnetically coupled Ising spins (the so-called Glauber dynamics). In 2002, this new class of nanomagnets was named single-chain magnets (SCMs) by analogy to single-molecule magnets that are isolated molecules displaying related superparamagnetic properties. A long-range order occurs only at T = 0 K in any pure one-dimensional (1D) system, and thus such systems remain in their paramagnetic state at any finite temperature. Nevertheless, the combined action of large uniaxial anisotropy and intrachain magnetic interactions between high-spin magnetic units of the 1D arrangement promotes long relaxation times for the magnetization reversal with decreasing temperature, and finally at significantly low temperatures, the material can behave as a magnet. In this Forum Article, we summarize simple theoretical approaches used for understanding typical SCM behavior and some rational synthetic strategies to obtain SCM materials together with representative examples of SCMs previously reported.

  15. Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes

    PubMed Central

    Caviston, Juliane P.; Zajac, Allison L.; Tokito, Mariko; Holzbaur, Erika L.F.

    2011-01-01

    Huntingtin (Htt) is a membrane-associated scaffolding protein that interacts with microtubule motors as well as actin-associated adaptor molecules. We examined a role for Htt in the dynein-mediated intracellular trafficking of endosomes and lysosomes. In HeLa cells depleted of either Htt or dynein, early, recycling, and late endosomes (LE)/lysosomes all become dispersed. Despite altered organelle localization, kinetic assays indicate only minor defects in intracellular trafficking. Expression of full-length Htt is required to restore organelle localization in Htt-depleted cells, supporting a role for Htt as a scaffold that promotes functional interactions along its length. In dynein-depleted cells, LE/lysosomes accumulate in tight patches near the cortex, apparently enmeshed by cortactin-positive actin filaments; Latrunculin B-treatment disperses these patches. Peripheral LE/lysosomes in dynein-depleted cells no longer colocalize with microtubules. Htt may be required for this off-loading, as the loss of microtubule association is not seen in Htt-depleted cells or in cells depleted of both dynein and Htt. Inhibition of kinesin-1 relocalizes peripheral LE/lysosomes induced by Htt depletion but not by dynein depletion, consistent with their detachment from microtubules upon dynein knockdown. Together, these data support a model of Htt as a facilitator of dynein-mediated trafficking that may regulate the cytoskeletal association of dynamic organelles. PMID:21169558

  16. Dynamic engagement of human motion detectors across space-time coordinates.

    PubMed

    Neri, Peter

    2014-06-18

    Motion detection is a fundamental property of the visual system. The gold standard for studying and understanding this function is the motion energy model. This computational tool relies on spatiotemporally selective filters that capture the change in spatial position over time afforded by moving objects. Although the filters are defined in space-time, their human counterparts have never been studied in their native spatiotemporal space but rather in the corresponding frequency domain. When this frequency description is back-projected to spatiotemporal description, not all characteristics of the underlying process are retained, leaving open the possibility that important properties of human motion detection may have remained unexplored. We derived descriptors of motion detectors in native space-time, and discovered a large unexpected dynamic structure involving a >2× change in detector amplitude over the first ∼100 ms. This property is not predicted by the energy model, generalizes across the visual field, and is robust to adaptation; however, it is silenced by surround inhibition and is contrast dependent. We account for all results by extending the motion energy model to incorporate a small network that supports feedforward spread of activation along the motion trajectory via a simple gain-control circuit. PMID:24948800

  17. Simultaneous dynamic electrical and structural measurements of functional materials

    NASA Astrophysics Data System (ADS)

    Vecchini, C.; Thompson, P.; Stewart, M.; Muñiz-Piniella, A.; McMitchell, S. R. C.; Wooldridge, J.; Lepadatu, S.; Bouchenoire, L.; Brown, S.; Wermeille, D.; Bikondoa, O.; Lucas, C. A.; Hase, T. P. A.; Lesourd, M.; Dontsov, D.; Cain, M. G.

    2015-10-01

    A new materials characterization system developed at the XMaS beamline, located at the European Synchrotron Radiation Facility in France, is presented. We show that this new capability allows to measure the atomic structural evolution (crystallography) of piezoelectric materials whilst simultaneously measuring the overall strain characteristics and electrical response to dynamically (ac) applied external stimuli.

  18. Simultaneous dynamic electrical and structural measurements of functional materials

    SciTech Connect

    Vecchini, C.; Stewart, M.; Muñiz-Piniella, A.; Wooldridge, J.; Thompson, P.; McMitchell, S. R. C.; Bouchenoire, L.; Brown, S.; Wermeille, D.; Lucas, C. A.; Lepadatu, S.; Bikondoa, O.; Hase, T. P. A.; Lesourd, M.; Dontsov, D.; Cain, M. G.

    2015-10-15

    A new materials characterization system developed at the XMaS beamline, located at the European Synchrotron Radiation Facility in France, is presented. We show that this new capability allows to measure the atomic structural evolution (crystallography) of piezoelectric materials whilst simultaneously measuring the overall strain characteristics and electrical response to dynamically (ac) applied external stimuli.

  19. Distributed dynamic strain measurement using optical frequency-domain reflectometry.

    PubMed

    Zhou, Da-Peng; Chen, Liang; Bao, Xiaoyi

    2016-08-20

    Distributed dynamic strain measurement based on optical frequency-domain reflectometry is proposed. The technique makes use of the wide scanning range of a tunable laser source in a short sweeping time, and subdivides the overall spectrum into narrower frequency windows. The advantage of subdividing the laser spectral range is to improve the measurement uncertainty induced by the laser wavelength difference between repeated scans. The noise-limited dynamic strain resolution is investigated experimentally, indicating that a minimum detectable strain is less than 200 nε for a spatial resolution of 20 cm. By measuring the subdivided spectral shifts in the time sequence along the sensing fiber, the dynamic strain can be properly quantified over a 30 m measurement range for a highest sampling rate of up to 50 Hz. PMID:27556996

  20. The new pelagic Operational Observatory of the Catalan Sea (OOCS) for the multisensor coordinated measurement of atmospheric and oceanographic conditions.

    PubMed

    Bahamon, Nixon; Aguzzi, Jacopo; Bernardello, Raffaele; Ahumada-Sempoal, Miguel-Angel; Puigdefabregas, Joan; Cateura, Jordi; Muñoz, Eduardo; Velásquez, Zoila; Cruzado, Antonio

    2011-01-01

    The new pelagic Operational Observatory of the Catalan Sea (OOCS) for the coordinated multisensor measurement of atmospheric and oceanographic conditions has been recently installed (2009) in the Catalan Sea (41°39'N, 2°54'E; Western Mediterranean) and continuously operated (with minor maintenance gaps) until today. This multiparametric platform is moored at 192 m depth, 9.3 km off Blanes harbour (Girona, Spain). It is composed of a buoy holding atmospheric sensors and a set of oceanographic sensors measuring the water conditions over the upper 100 m depth. The station is located close to the head of the Blanes submarine canyon where an important multispecies pelagic and demersal fishery gives the station ecological and economic relevance. The OOCS provides important records on atmospheric and oceanographic conditions, the latter through the measurement of hydrological and biogeochemical parameters, at depths with a time resolution never attained before for this area of the Mediterranean. Twenty four moored sensors and probes operating in a coordinated fashion provide important data on Essential Ocean Variables (EOVs; UNESCO) such as temperature, salinity, pressure, dissolved oxygen, chlorophyll fluorescence, and turbidity. In comparison with other pelagic observatories presently operating in other world areas, OOCS also measures photosynthetic available radiation (PAR) from above the sea surface and at different depths in the upper 50 m. Data are recorded each 30 min and transmitted in real-time to a ground station via GPRS. This time series is published and automatically updated at the frequency of data collection on the official OOCS website (http://www.ceab.csic.es/~oceans). Under development are embedded automated routines for the in situ data treatment and assimilation into numerical models, in order to provide a reliable local marine processing forecast. In this work, our goal is to detail the OOCS multisensor architecture in relation to the coordinated

  1. The New Pelagic Operational Observatory of the Catalan Sea (OOCS) for the Multisensor Coordinated Measurement of Atmospheric and Oceanographic Conditions

    PubMed Central

    Bahamon, Nixon; Aguzzi, Jacopo; Bernardello, Raffaele; Ahumada-Sempoal, Miguel-Angel; Puigdefabregas, Joan; Cateura, Jordi; Muñoz, Eduardo; Velásquez, Zoila; Cruzado, Antonio

    2011-01-01

    The new pelagic Operational Observatory of the Catalan Sea (OOCS) for the coordinated multisensor measurement of atmospheric and oceanographic conditions has been recently installed (2009) in the Catalan Sea (41°39′N, 2°54′E; Western Mediterranean) and continuously operated (with minor maintenance gaps) until today. This multiparametric platform is moored at 192 m depth, 9.3 km off Blanes harbour (Girona, Spain). It is composed of a buoy holding atmospheric sensors and a set of oceanographic sensors measuring the water conditions over the upper 100 m depth. The station is located close to the head of the Blanes submarine canyon where an important multispecies pelagic and demersal fishery gives the station ecological and economic relevance. The OOCS provides important records on atmospheric and oceanographic conditions, the latter through the measurement of hydrological and biogeochemical parameters, at depths with a time resolution never attained before for this area of the Mediterranean. Twenty four moored sensors and probes operating in a coordinated fashion provide important data on Essential Ocean Variables (EOVs; UNESCO) such as temperature, salinity, pressure, dissolved oxygen, chlorophyll fluorescence, and turbidity. In comparison with other pelagic observatories presently operating in other world areas, OOCS also measures photosynthetic available radiation (PAR) from above the sea surface and at different depths in the upper 50 m. Data are recorded each 30 min and transmitted in real-time to a ground station via GPRS. This time series is published and automatically updated at the frequency of data collection on the official OOCS website (http://www.ceab.csic.es/~oceans). Under development are embedded automated routines for the in situ data treatment and assimilation into numerical models, in order to provide a reliable local marine processing forecast. In this work, our goal is to detail the OOCS multisensor architecture in relation to the

  2. The new pelagic Operational Observatory of the Catalan Sea (OOCS) for the multisensor coordinated measurement of atmospheric and oceanographic conditions.

    PubMed

    Bahamon, Nixon; Aguzzi, Jacopo; Bernardello, Raffaele; Ahumada-Sempoal, Miguel-Angel; Puigdefabregas, Joan; Cateura, Jordi; Muñoz, Eduardo; Velásquez, Zoila; Cruzado, Antonio

    2011-01-01

    The new pelagic Operational Observatory of the Catalan Sea (OOCS) for the coordinated multisensor measurement of atmospheric and oceanographic conditions has been recently installed (2009) in the Catalan Sea (41°39'N, 2°54'E; Western Mediterranean) and continuously operated (with minor maintenance gaps) until today. This multiparametric platform is moored at 192 m depth, 9.3 km off Blanes harbour (Girona, Spain). It is composed of a buoy holding atmospheric sensors and a set of oceanographic sensors measuring the water conditions over the upper 100 m depth. The station is located close to the head of the Blanes submarine canyon where an important multispecies pelagic and demersal fishery gives the station ecological and economic relevance. The OOCS provides important records on atmospheric and oceanographic conditions, the latter through the measurement of hydrological and biogeochemical parameters, at depths with a time resolution never attained before for this area of the Mediterranean. Twenty four moored sensors and probes operating in a coordinated fashion provide important data on Essential Ocean Variables (EOVs; UNESCO) such as temperature, salinity, pressure, dissolved oxygen, chlorophyll fluorescence, and turbidity. In comparison with other pelagic observatories presently operating in other world areas, OOCS also measures photosynthetic available radiation (PAR) from above the sea surface and at different depths in the upper 50 m. Data are recorded each 30 min and transmitted in real-time to a ground station via GPRS. This time series is published and automatically updated at the frequency of data collection on the official OOCS website (http://www.ceab.csic.es/~oceans). Under development are embedded automated routines for the in situ data treatment and assimilation into numerical models, in order to provide a reliable local marine processing forecast. In this work, our goal is to detail the OOCS multisensor architecture in relation to the coordinated

  3. Recent Themis and Coordinated GBO Measurements of Substorm Expansion Onset: Do We Finally Have an Answer?

    NASA Technical Reports Server (NTRS)

    Kepko, Larry

    2011-01-01

    For nearly 30 years an often-times heated debate has engaged the substorm community: Do substorms begin with the formation of a new reconnection site in the midtail plasmasheet (the Near-Earth Neutral Line model) or do they begin near the transition region between stretched tail and dipolar field lines (the Current Disruption model). The THEMIS mission, with a coordinated suite of five in-situ spacecraft and ground observatories. has greatly extended our understanding of how substorms initiate and evolve. But have the new data resolved the fundamental question? In this talk I review the last few year's of substorm research, with an emphasis of how the THEMIS data have revolutionized our understanding.

  4. Recent THEMIS and Coordinated GBO Measurements of Substorm Expansion Onset: Do We Finally Have an Answer?

    NASA Technical Reports Server (NTRS)

    Kepko, L.

    2011-01-01

    For nearly 30 years an often-times heated debate has engaged the substorm community: Do substorms begin with the formation of a new reconnection site in the midtail plasma sheet (the Near-Earth Neutral Line model) or do they begin near the transition region between stretched tail and dipolar field lines (the Current Disruption model). The THEMIS mission, with a coordinated suite of five in-situ spacecraft and ground observatories, has greatly extended our understanding of how substorms initiate and evolve. But have the new data resolved the fundamental question? In this talk I review the last few year's of sub storm research, with an emphasis of how the THEMIS data have revolutionized our understanding.

  5. Setting the Stage: Measure Selection, Coordination, and Data Collection for a National Self-Management Initiative

    PubMed Central

    Kulinski, Kristie P.; Boutaugh, Michele; Smith, Matthew Lee; Ory, Marcia G.; Lorig, Kate

    2015-01-01

    This paper describes the history and rationale behind the development of a centralized data collection system for the national rollout of the Chronic Disease Self-Management Program (CDSMP) through the American Recovery and Reinvestment Act of 2009 Communities Putting Prevention to Work: CDSMP initiative. In addition to justifying the need for solutions to the burgeoning burden of chronic disease in the United States, this paper provides details about CDSMP and related self-management education programs, including their structure, facilitator training, and effectiveness. These topics set the stage for the processes and procedures to create and manage the database for use at the national, state, and local levels. Furthermore, this paper describes the processes related to selecting variables, coordinating data collection, and utilizing data to inform research and policy. PMID:25964919

  6. Measuring the Dynamic Parameters of MCF7 Cell Microtubules

    NASA Astrophysics Data System (ADS)

    Winton, Carly; Shojania Feizabadi, Mitra

    2013-03-01

    Microtubules are the key component of the cytoskeleton. They are intrinsically dynamic displaying dynamic instability in which they randomly switch between a phase of growing and shrinking, both in vitro and in vivo. This dynamic is specified by the following parameters: growing rate, shrinking rate, frequency of catastrophe, and frequency of rescue. In this work, we will present our primary results in which we measured the dynamic parameters of a single microtubule polymerized from MCF7 tubulin in vitro. The results are significant since the MCF7 microtubules are non-neural mammalian consisting of different beta tubulin isotypes in their structures as compared to neural mammalian microtubules, such as bovine brain. The unique dynamic parameters of individual MCF7 microtubules in vitro, which are reported for the first time, indicate that non-neural microtubules can be fundamentally different from neural microtubules.

  7. Introducing Variable-Step Topography (VST) coordinates within dynamically constrained Nonhydrostatic Modeling System (NMS). Part 1: VST formulation within NMS host model framework

    NASA Astrophysics Data System (ADS)

    Tripoli, Gregory J.; Smith, Eric A.

    2014-06-01

    A Variable-Step Topography (VST) surface coordinate system is introduced into a dynamically constrained, scalable, nonhydrostatic atmospheric model for reliable simulations of flows over both smooth and steep terrain without sacrificing dynamical integrity over either type of surface. Backgrounds of both terrain-following and step coordinate model developments are presented before justifying the turn to a VST approach within an appropriately configured host model. In this first part of a two-part sequence of papers, the full formulation of the VST model, prefaced by a description of the framework of its apposite host, i.e., a re-tooled Nonhydrostatic Modeling System (NMS), are presented. [The second part assesses the performance and benefits of the new VST coordinate system in conjunction with seven orthodox obstacle flow problems.] The NMS is a 3-dimensional, nonhydrostatic cloud-mesoscale model, designed for integrations from plume-cloud scales out to regional-global scales. The derivative properties of VST in conjunction with the NMS's newly designed dynamically constrained core are capable of accurately capturing the deformations of flows by any type of terrain variability. Numerical differencing schemes needed to satisfy critical integral constraints, while also effectively enabling the VST lower boundary, are described. The host model constraints include mass, momentum, energy, vorticity and enstrophy conservation. A quasi-compressible closure cast on multiple-nest rotated spherical grids is the underlying framework used to study the advantages of the VST coordinate system. The principle objective behind the VST formulation is to combine the advantages of both terrain-following and step coordinate systems without suffering either of their disadvantages, while at the same time creating a vertical surface coordinate setting suitable for a scalable, nonhydrostatic model, safeguarded with physically realistic dynamical constraints.

  8. Vertical Dynamic Deflection Measurement in Concrete Beams with the Microsoft Kinect

    PubMed Central

    Qi, Xiaojuan; Lichti, Derek; El-Badry, Mamdouh; Chow, Jacky; Ang, Kathleen

    2014-01-01

    The Microsoft Kinect is arguably the most popular RGB-D camera currently on the market, partially due to its low cost. It offers many advantages for the measurement of dynamic phenomena since it can directly measure three-dimensional coordinates of objects at video frame rate using a single sensor. This paper presents the results of an investigation into the development of a Microsoft Kinect-based system for measuring the deflection of reinforced concrete beams subjected to cyclic loads. New segmentation methods for object extraction from the Kinect's depth imagery and vertical displacement reconstruction algorithms have been developed and implemented to reconstruct the time-dependent displacement of concrete beams tested in laboratory conditions. The results demonstrate that the amplitude and frequency of the vertical displacements can be reconstructed with submillimetre and milliHz-level precision and accuracy, respectively. PMID:24556668

  9. Cumulative Measurement Errors for Dynamic Testing of Space Flight Hardware

    NASA Technical Reports Server (NTRS)

    Winnitoy, Susan

    2012-01-01

    Located at the NASA Johnson Space Center in Houston, TX, the Six-Degree-of-Freedom Dynamic Test System (SDTS) is a real-time, six degree-of-freedom, short range motion base simulator originally designed to simulate the relative dynamics of two bodies in space mating together (i.e., docking or berthing). The SDTS has the capability to test full scale docking and berthing systems utilizing a two body dynamic docking simulation for docking operations and a Space Station Remote Manipulator System (SSRMS) simulation for berthing operations. The SDTS can also be used for nonmating applications such as sensors and instruments evaluations requiring proximity or short range motion operations. The motion base is a hydraulic powered Stewart platform, capable of supporting a 3,500 lb payload with a positional accuracy of 0.03 inches. The SDTS is currently being used for the NASA Docking System testing and has been also used by other government agencies. The SDTS is also under consideration for use by commercial companies. Examples of tests include the verification of on-orbit robotic inspection systems, space vehicle assembly procedures and docking/berthing systems. The facility integrates a dynamic simulation of on-orbit spacecraft mating or de-mating using flight-like mechanical interface hardware. A force moment sensor is used for input during the contact phase, thus simulating the contact dynamics. While the verification of flight hardware presents unique challenges, one particular area of interest involves the use of external measurement systems to ensure accurate feedback of dynamic contact. The measurement systems for the test facility have two separate functions. The first is to take static measurements of facility and test hardware to determine both the static and moving frames used in the simulation and control system. The test hardware must be measured after each configuration change to determine both sets of reference frames. The second function is to take dynamic

  10. Models for the prediction of polar coordinates of lunar reflectors in the dynamic Earth-Moon system

    NASA Astrophysics Data System (ADS)

    Teichert, B. D.

    Two models for the prediction of polar coordinates of reflectors installed on the Moon were investigated with respect to their usefulness for Lunar Laser Ranging (LLR). The first model is purely mechanical-analytical, and is based on the Brown Moon theory and on the Moon rotation and libration theory. The second method applies recursive filter algorithms using Kalman filtering. Data from laser ranging measurements were compared with data obtained with both models. Both models fulfil the required accuracy, and are more or less equivalent, with respect to the accuracy of the predictions of azimuth and elevation. However, for range, the Kalman filtering method is preferable. The FORTRAN computer programs for the Kalman filtering are enclosed.

  11. Dynamic Tire Pressure Sensor for Measuring Ground Vibration

    PubMed Central

    Wang, Qi; McDaniel, James Gregory; Wang, Ming L.

    2012-01-01

    This work presents a convenient and non-contact acoustic sensing approach for measuring ground vibration. This approach, which uses an instantaneous dynamic tire pressure sensor (DTPS), possesses the capability to replace the accelerometer or directional microphone currently being used for inspecting pavement conditions. By measuring dynamic pressure changes inside the tire, ground vibration can be amplified and isolated from environmental noise. In this work, verifications of the DTPS concept of sensing inside the tire have been carried out. In addition, comparisons between a DTPS, ground-mounted accelerometer, and directional microphone are made. A data analysis algorithm has been developed and optimized to reconstruct ground acceleration from DTPS data. Numerical and experimental studies of this DTPS reveal a strong potential for measuring ground vibration caused by a moving vehicle. A calibration of transfer function between dynamic tire pressure change and ground acceleration may be needed for different tire system or for more accurate application. PMID:23202206

  12. Dynamic tire pressure sensor for measuring ground vibration.

    PubMed

    Wang, Qi; McDaniel, James Gregory; Wang, Ming L

    2012-11-07

    This work presents a convenient and non-contact acoustic sensing approach for measuring ground vibration. This approach, which uses an instantaneous dynamic tire pressure sensor (DTPS), possesses the capability to replace the accelerometer or directional microphone currently being used for inspecting pavement conditions. By measuring dynamic pressure changes inside the tire, ground vibration can be amplified and isolated from environmental noise. In this work, verifications of the DTPS concept of sensing inside the tire have been carried out. In addition, comparisons between a DTPS, ground-mounted accelerometer, and directional microphone are made. A data analysis algorithm has been developed and optimized to reconstruct ground acceleration from DTPS data. Numerical and experimental studies of this DTPS reveal a strong potential for measuring ground vibration caused by a moving vehicle. A calibration of transfer function between dynamic tire pressure change and ground acceleration may be needed for different tire system or for more accurate application.

  13. Dynamic fracture toughness evaluation by measurement of CTOD

    SciTech Connect

    Sharpe, W.N. Jr.; Douglas, A.S.; Shapiro, J.M.

    1988-02-01

    Quantification of the dynamic fracture toughness of structural materials is essential to a wide range of problems-from nuclear accidents to ordnance applications. However, the difficulties associated with accurate measurements of crack under dynamic loading are considerable. Thus there are no standardized procedures and few reliable results. A systematic study of the dynamic fracture toughness of SAE-01 tool steel, 4340 and HY100 steels, and a tungsten are described using the Interferometric Strain/Displacement Gage (ISDG) system which has very high frequency resolution. The ISDG system is used to measure the crack tip opening displacement (CTOD) 100 microns behind a fatigue crack tip in a three-point bend specimen. Static measurements on similar specimens serve to calibrate the method and ensure consistency with the accepted procedures for static fracture toughness testing. Finite element analyses are used to obtain full field information at the point of initiation and to assess the material characteristics which lead to changes in toughness with loading rate. The major advantage of the method is that information is obtained very close to the crack tip, so that stress wave loading effects are accounted for. Results show that 4340 steel, which is strain-rate insensitive, has no significant change in toughness with loading rate. Measurable toughness dependence on loading rate is found for HY-100 and tungsten, which are approximately 15 percent tougher under dynamic conditions. The SAE-01 tool steel shows a significant increase (50 percent) in fracture toughness for dynamic over static loading.

  14. Rayleigh Scattering Diagnostic for Dynamic Measurement of Velocity and Temperature

    NASA Technical Reports Server (NTRS)

    Seasholtz, Richard G.; Panda, J.

    2001-01-01

    A new technique for measuring dynamic gas velocity and temperature is described. The technique is based on molecular Rayleigh scattering of laser light, so no seeding of the flow is necessary. The Rayleigh scattered light is filtered with a fixed cavity, planar mirror Fabry-Perot interferometer. A minimum number of photodetectors were used in order to allow the high data acquisition rate needed for dynamic measurements. One photomultiplier tube (PMT) was used to measure the total Rayleigh scattering, which is proportional to the gas density. Two additional PMTs were used to detect light that passes through two apertures in a mask located in the interferometer fringe plane. An uncertainty analysis was used to select the optimum aperture parameters and to predict the measurement uncertainty due to photon shot-noise. Results of an experiment to measure the velocity of a subsonic free jet are presented.

  15. Quantitative measures to reveal coordinated cytoskeleton-nucleus reorganization during in vitro invasion of cancer cells

    NASA Astrophysics Data System (ADS)

    Dvir, Liron; Nissim, Ronen; Alvarez-Elizondo, Martha B.; Weihs, Daphne

    2015-04-01

    Metastasis formation is a major cause of mortality in cancer patients and includes tumor cell relocation to distant organs. A metastatic cell invades through other cells and extracellular matrix by biochemical attachment and mechanical force application. Force is used to move on or through a 2- or 3-dimensional (3D) environment, respectively, or to penetrate a 2D substrate. We have previously shown that even when a gel substrate is impenetrable, metastatic breast cancer cells can still indent it by applying force. Cells typically apply force through the acto-myosin network, which is mechanically connected to the nucleus. We develop a 3D image-analysis to reveal relative locations of the cell elements, and show that as cells apply force to the gel, a coordinated process occurs that involves cytoskeletal remodeling and repositioning of the nucleus. Our approach shows that the actin and microtubules reorganize in the cell, bringing the actin to the leading edge of the cell. In parallel, the nucleus is transported behind the actin, likely by the cytoskeleton, into the indentation dimple formed in the gel. The nucleus volume below the gel surface correlates with indentation depth, when metastatic breast cancer cells indent gels deeply. However, the nucleus always remains above the gel in benign cells, even when small indentations are observed. Determining mechanical processes during metastatic cell invasion can reveal how cells disseminate in the body and can uncover targets for diagnosis and treatment.

  16. Coordinated ground-based and geosynchronous satellite-based measurements of auroral pulsations

    SciTech Connect

    Suszcynsky, David M.; Borovsky, Joseph E.; Thomsen, Michelle F.; McComas, David J.; Belian, Richard D.

    1996-09-01

    We describe a technique that uses a ground-based all-sky video camera and geosynchronous satellite-based plasma and energetic particle detectors to study ionosphere-magnetosphere coupling as it relates to the aurora. The video camera system was deployed in Eagle, Alaska for a seven month period at the foot of the magnetic field line that threads geosynchronous satellite 1989-046. Since 1989-046 corotates with the earth, its footprint remains nearly fixed in the vicinity of Eagle, allowing for routine continuous monitoring of an auroral field line at its intersections with the ground and with geosynchronous orbit. As an example of the utility of this technique, we present coordinated ground-based and satellite based observations during periods of auroral pulsations and compare this data to the predictions of both the relaxation oscillator theory and flow cyclotron maser theory for the generation of pulsating aurorae. The observed plasma and energetic particle characteristics at geosynchronous orbit during pulsating aurorae displays are found to be in agreement with the predictions of both theories lending further support that a cyclotron resonance mechanism is responsible for auroral pulsations.

  17. Coordination numbers of K(+) and Na(+) Ions inside the selectivity filter of the KcsA potassium channel: insights from first principles molecular dynamics.

    PubMed

    Bucher, Denis; Guidoni, Leonardo; Carloni, Paolo; Rothlisberger, Ursula

    2010-05-19

    Quantum mechanics/molecular mechanics (QM/MM) Car-Parrinello simulations were performed to estimate the coordination numbers of K(+) and Na(+) ions in the selectivity filter of the KcsA channel, and in water. At the DFT/BLYP level, K(+) ions were found to display an average coordination number of 6.6 in the filter, and 6.2 in water. Na(+) ions displayed an average coordination number of 5.2 in the filter, and 5.0 in water. A comparison was made with the average coordination numbers obtained from using classical molecular dynamics (6.7 for K(+) in the filter, 6.6 for K(+) in water, 6.0 for Na(+) in the filter, and 5.2 for Na(+) in water). The observation that different coordination numbers were displayed by the ions in QM/MM simulations and in classical molecular dynamics is relevant to the discussion of selectivity in K-channels.

  18. Application of the trajectory coordinate system and the moving modes method approach to railroad dynamics using Krylov subspaces

    NASA Astrophysics Data System (ADS)

    Recuero, Antonio M.; Escalona, José L.

    2013-09-01

    This paper presents a procedure that makes use of a particular formulation based on the trajectory coordinate system (TCS) approach, which is specific of ground vehicles, to describe the track deformation by means of a suitable set of mode shapes. The inertia terms of the track elastic displacements are derived using the TCS arc length to couple the system dynamics. The selection of the track modes of deformation is carried out from a finite element model by using Krylov subspaces as the model-order reduction technique. The modes of deformation move along the track fixed to the TCS using the moving modes method (MMM), avoiding the issue concerning the spatial convergence of the load (wheels) on the track and preserving their vertical frequency contents whose accuracy can be chosen beforehand. An unsuspended wheelset with an induced hunting motion moving on flexible and rigid tangent tracks and a vehicle model are simulated using rail defects as excitations sources such that the performance of this procedure using a fully 3D contact algorithm is shown and analyzed.

  19. The dynamics of the tundra-taiga boundary: an overview and suggested coordinated and integrated approach to research.

    PubMed

    Callaghan, Terry V; Crawford, Robert M M; Eronen, Matti; Hofgaard, Annika; Payette, Serge; Rees, W Gareth; Skre, Oddvar; Sveinbjörnsson, Bjartmar; Vlassova, Tatiana K; Werkman, Ben R

    2002-08-01

    The tundra-taiga boundary stretches for more than 13,400 km around the Northern Hemisphere and is probably the Earth's greatest vegetation transition. The trees that define the boundary have been sensitive to climate changes in the past and models of future vegetation distribution suggest a rapid and dramatic invasion of the tundra by the taiga. Such changes would generate both positive and negative feedbacks to the climate system and the balance could result in a net warming effect. However, the boundary is becoming increasingly affected by human activities that remove trees and degrade forest-tundra into tundra-like areas. Because of the vastness and remoteness of the tundra-taiga boundary, and of methodological problems such as problematic definitions and lack of standardized methods to record the location and characteristics of the ecotone, a project group has been established under the auspices of the International Arctic Science Committee (IASC). This paper summarizes the initial output of the group and focuses on our uncertainties in understanding the current processes at the tundra-taiga boundary and the conflicts between model predictions of changes in the location of the boundary and contrasting recently observed changes due to human activities. Finally, we present recommendations for a coordinated international approach to the problem and invite the international community to join us in reducing the uncertainties about the dynamics of the ecotone and their consequences.

  20. Essential Measures for Student Success: Implementing Cooperation, Collaboration, and Coordination between Schools and Parents

    ERIC Educational Resources Information Center

    Kirby, Edwena

    2012-01-01

    This book unveils "essential measures" that create a revitalized educational system of which educators and parents can use to promote student success. When these measures are applied properly, the benefits include, eradicating student fear, elevating student motivation, improving school attendance, and reducing student dropout rates. These…

  1. High-speed scanning of critical structures in aviation using coordinate measurement machine and the laser ultrasonic.

    PubMed

    Swornowski, Pawel J

    2012-01-01

    Aviation is one of the know-how spheres containing a great deal of responsible sub-assemblies, in this case landing gear. The necessity for reducing production cycle times while achieving better quality compels metrologists to look for new and improved ways to perform inspection of critical structures. This article describes the ability to determine the shape deviation and location of defects in landing gear using coordinate measuring machines and laser ultrasonic with high-speed scanning. A nondestructive test is the basis for monitoring microcrack and corrosion propagation in the context of a damage-tolerant design approach. This article presents an overview of the basics and of the various metrological aspects of coordinate measurement and a nondestructive testing method in terms of high-speed scanning. The new test method (laser ultrasonic) promises to produce the necessary increase in inspection quality, but this is limited by the wide range of materials, geometries, and structure aeronautic parts used. A technique combining laser ultrasonic and F-SAFT (Fourier-Synthetic Aperture Focusing Technique) processing has been proposed for the detection of small defects buried in landing gear. The experimental results of landing gear inspection are also presented. PMID:22700384

  2. High-speed scanning of critical structures in aviation using coordinate measurement machine and the laser ultrasonic.

    PubMed

    Swornowski, Pawel J

    2012-01-01

    Aviation is one of the know-how spheres containing a great deal of responsible sub-assemblies, in this case landing gear. The necessity for reducing production cycle times while achieving better quality compels metrologists to look for new and improved ways to perform inspection of critical structures. This article describes the ability to determine the shape deviation and location of defects in landing gear using coordinate measuring machines and laser ultrasonic with high-speed scanning. A nondestructive test is the basis for monitoring microcrack and corrosion propagation in the context of a damage-tolerant design approach. This article presents an overview of the basics and of the various metrological aspects of coordinate measurement and a nondestructive testing method in terms of high-speed scanning. The new test method (laser ultrasonic) promises to produce the necessary increase in inspection quality, but this is limited by the wide range of materials, geometries, and structure aeronautic parts used. A technique combining laser ultrasonic and F-SAFT (Fourier-Synthetic Aperture Focusing Technique) processing has been proposed for the detection of small defects buried in landing gear. The experimental results of landing gear inspection are also presented.

  3. A growing-drop technique for measuring dynamic interfacial tension

    SciTech Connect

    MacLeod, C.A.; Radke, C.J.

    1993-10-01

    A novel, growing-drop technique is described for measuring dynamic interfacial tension due to sorption of surface-active solutes. The proposed method relates the instantaneous pressure and size of expanding liquid drops to interfacial tension and is useful for measuring both liquid/gas and liquid/liquid tensions over a wide range of time scales, currently from 10 ms to several hours. Growing-drop measurements on surfactant-free water/air and water/octanol interfaces yield constant tensions equal to their known literature values. For surfactant-laden, liquid drops, the growing-drop technique captures the actual transient tension evolution of a single interface, rather than interval times as with the classic maximum-drop-pressure and drop.-volume tension measurements. Dynamic tensions measured for 0.25 mM aqueous 1-decanol solution/air and 0.02 kg/m{sup 3} aqueous Triton X-100 solution/dodecane interfaces show nonmonotonic behavior, indicating slow surfactant transport relative to the imposed rates of interfacial dilatation. The dynamic tension of a purified and fresh 6 mM aqueous sodium dodecyl sulfate (SDS) solution/air interface shows only a monotonic decrease, indicating rapid surfactant transport relative to the imposed rates of dilatation. ConverselY, an aged SDS solution, naturally containing trace dodecanol impurities, exhibits dynamic tensions which reflect a superposition of the rapidly equilibrating SDS and the slowly adsorbing dodecanol.

  4. A theory of neural dimensionality, dynamics, and measurement

    NASA Astrophysics Data System (ADS)

    Ganguli, Surya

    In many experiments, neuroscientists tightly control behavior, record many trials, and obtain trial-averaged firing rates from hundreds of neurons in circuits containing millions of behaviorally relevant neurons. Dimensionality reduction has often shown that such datasets are strikingly simple; they can be described using a much smaller number of dimensions than the number of recorded neurons, and the resulting projections onto these dimensions yield a remarkably insightful dynamical portrait of circuit computation. This ubiquitous simplicity raises several profound and timely conceptual questions. What is the origin of this simplicity and its implications for the complexity of brain dynamics? Would neuronal datasets become more complex if we recorded more neurons? How and when can we trust dynamical portraits obtained from only hundreds of neurons in circuits containing millions of neurons? We present a theory that answers these questions, and test it using neural data recorded from reaching monkeys. Overall, this theory yields a picture of the neural measurement process as a random projection of neural dynamics, conceptual insights into how we can reliably recover dynamical portraits in such under-sampled measurement regimes, and quantitative guidelines for the design of future experiments. Moreover, it reveals the existence of phase transition boundaries in our ability to successfully decode cognition and behavior as a function of the number of recorded neurons, the complexity of the task, and the smoothness of neural dynamics. membership pending.

  5. Hydrothermal alteration and diagenesis of terrestrial lacustrine pillow basalts: Coordination of hyperspectral imaging with laboratory measurements

    USGS Publications Warehouse

    Greenberger, Rebecca N; Mustard, John F; Cloutis, Edward A; Mann, Paul; Wilson, Janette H.; Flemming, Roberta L; Robertson, Kevin; Salvatore, Mark R; Edwards, Christopher

    2015-01-01

    The phases identified in the sample are albite, large iron oxides, and titanite throughout; calcite in vesicles; calcic clinopyroxene, aegirine, and Fe/Mg-bearing clay in the rind; and fine-grained hematite and pyroxenes in the interior. Using imaging spectroscopy, the chemistry and mineralogy results extend to the hand sample and larger outcrop. From all of the analyses, we suggest that the pillow basalts were altered initially after emplacement, either by heated lake water or magmatic fluids, at temperatures of at least 400-600°C, and the calcic clinopyroxenes and aegirine identified in the rind are a preserved record of that alteration. As the hydrothermal system cooled to slightly lower temperatures, clays formed in the rind, and, during this alteration, the sample oxidized to form hematite in the matrix of the interior and Fe3+ in the pyroxenes in the rind. During the waning stages of the hydrothermal system, calcite precipitated in vesicles within the rind. Later, diagenetic processes albitized the sample, with albite replacing plagioclase, lining vesicles, and accreting onto the exterior of the sample. This albitization or Na-metasomatism occurred when the lake within the Hartford Basin evaporated during a drier past climatic era, resulting in Na-rich brines. As Ca-rich plagioclase altered to albite, Ca was released into solution, eventually precipitating as calcite in previously-unfilled vesicles, dominantly in the interior of the pillow. Coordinated analyses of this sample permit identification of the alteration phases and help synthesize the aqueous history of pillow lavas of the Talcott formation. These results are also relevant to Mars, where volcanically-resurfaced open basin lakes have been found, and this Hartford Basin outcrop may be a valuable analog for any potential volcano-lacustrine interactions. The results can also help to inform the utility and optimization of potentially complementary, synergistic, and uniquely-suited techniques for

  6. Objective and automated measurement of dynamic vision functions

    NASA Technical Reports Server (NTRS)

    Flom, M. C.; Adams, A. J.

    1976-01-01

    A phoria stimulus array and electro-oculographic (EOG) arrangements for measuring motor and sensory responses of subjects subjected to stress or drug conditions are described, along with experimental procedures. Heterophoria (as oculomotor function) and glare recovery time (time required for photochemical and neural recovery after exposure to a flash stimulus) are measured, in research aimed at developing automated objective measurement of dynamic vision functions. Onset of involuntary optokinetic nystagmus in subjects attempting to track moving stripes (while viewing through head-mounted binocular eyepieces) after exposure to glare serves as an objective measure of glare recovery time.

  7. Scale-Independent Measures and Pathologic Cardiac Dynamics

    NASA Astrophysics Data System (ADS)

    Amaral, Luís A.; Goldberger, Ary L.; Ivanov, Plamen Ch.; Stanley, H. Eugene

    1998-09-01

    We study several scale-independent measures of cardiac interbeat interval dynamics defined through the application of the wavelet transform. We test their performance in detecting heart disease using a database consisting of records of interbeat intervals for a group of healthy individuals and subjects with congestive heart failure. We find that scale-independent measures effectively distinguish healthy from pathologic behavior and propose a new two-variable scale-independent measure that could be clinically useful. We compare the performance of a recently proposed scale-dependent measure and find that the results depend on the database analyzed and on the analyzing wavelet.

  8. Coordinated Airborne, Spaceborne, and Ground-Based Measurements of Massive, Thick Aerosol Layers During the Dry Season in Southern Africa

    NASA Technical Reports Server (NTRS)

    Schmid, B.; Redemann, J.; Russell, P. B.; Hobbs, P. V.; Hlavka, D. L.; McGill, M. J.; Holben, B. N.; Welton, E. J.; Campbell, J.; Torres, O.; Hipskind, R. Stephen (Technical Monitor)

    2002-01-01

    During the dry-season airborne campaign of the Southern African Regional Science Initiative (SAFARI 2000), unique coordinated observations were made of massive, thick aerosol layers. These layers were often dominated by aerosols from biomass burning. We report on airborne Sunphotometer measurements of aerosol optical depth (lambda=354-1558 nm), columnar water vapor, and vertical profiles of aerosol extinction and water vapor density that were obtained aboard the University of Washington's Convair-580 research aircraft. We compare these with ground-based AERONET Sun/sky radiometer results, with ground based lidar data MPL-Net), and with measurements from a downward-pointing lidar aboard the high-flying NASA ER-2 aircraft. Finally, we show comparisons between aerosol optical depths from the Sunphotometer and those retrieved over land and over water using four spaceborne sensors (TOMS (Total Ozone Mapping Spectrometer), MODIS (Moderate Resolution Imaging Spectrometer), MISR (Multiangle Imaging Spectroradiometer) and ATSR-2 (Along Track Scanning Radiometer)).

  9. Coordinated Airborne, Spaceborne and Ground-based Measurements of Massive Thick Aerosol Layers during the Dry Season in Southern Africa

    NASA Technical Reports Server (NTRS)

    Schmid, B.; Redemann, J.; Russell, P. B.; Hobbs, P. V.; Hlavka, D. L.; McGill, M. J.; Holben, B. N.; Welton, E. J.; Campbell, J. R.; Torres, O.

    2003-01-01

    During the dry season airborne campaign of the Southern African Regional Science Initiative (SAFARI 2000), coordinated observations were made of massive thick aerosol layers. These layers were often dominated by aerosols from biomass burning. We report on airborne Sun photometer measurements of aerosol optical depth (lambda = 0.354- 1.557 microns), columnar water vapor, and vertical profiles of aerosol extinction and water vapor density that were obtained aboard the University of Washington's Convair-580 research aircraft. We compare these with ground-based AERONET Sun/sky radiometer results, with ground based lidar data (MPL-Net), and with measurements from a downward pointing lidar aboard the high-flying NASA ER-2 aircraft. Finally, we show comparisons between aerosol optical depths fiom the Sun photometer and those retrieved over land and over water using four spaceborne sensors (TOMS, MODIS, MISR, and ATSR-2).

  10. A method of measuring dynamic strain under electromagnetic forming conditions

    NASA Astrophysics Data System (ADS)

    Chen, Jinling; Xi, Xuekui; Wang, Sijun; Lu, Jun; Guo, Chenglong; Wang, Wenquan; Liu, Enke; Wang, Wenhong; Liu, Lin; Wu, Guangheng

    2016-04-01

    Dynamic strain measurement is rather important for the characterization of mechanical behaviors in electromagnetic forming process, but it has been hindered by high strain rate and serious electromagnetic interference for years. In this work, a simple and effective strain measuring technique for physical and mechanical behavior studies in the electromagnetic forming process has been developed. High resolution (˜5 ppm) of strain curves of a budging aluminum tube in pulsed electromagnetic field has been successfully measured using this technique. The measured strain rate is about 105 s-1, which depends on the discharging conditions, nearly one order of magnitude of higher than that under conventional split Hopkins pressure bar loading conditions (˜104 s-1). It has been found that the dynamic fracture toughness of an aluminum alloy is significantly enhanced during the electromagnetic forming, which explains why the formability is much larger under electromagnetic forging conditions in comparison with conventional forging processes.

  11. Development of a probing system for a micro-coordinate measuring machine by utilizing shear-force detection

    NASA Astrophysics Data System (ADS)

    Ito, So; Kodama, Issei; Gao, Wei

    2014-06-01

    This paper introduces a newly developed probing system for a micro-coordinate measurement machine (micro-CMM) based on an interaction force generated by the water layer on the surface of the measuring object. In order to measure the dimensions of the micrometric structures, a probing system using a nanopipette ball stylus has been developed. A glass microsphere with diameter of 9 µm is used as a stylus tip of the probing system. The glass nanopipette, which is fabricated from a capillary glass tube by a thermal pulling process, is employed as a stylus shaft to improve the fixation strength of the stylus tip. The approach between the stylus tip and the surface of the measuring object can be detected by utilizing the method of shear-force detection. The stylus is oscillated in the lateral direction at its resonant frequency to detect an interaction force owing to the viscoelasticity of the meniscus layer existing on the surface of the measuring object. The oscillation amplitude is decreased by the shear-force applied to the stylus tip. In this study, the basic characteristics of the probing system including sensitivity, resolution and reproducibility are investigated. The experimental result of dimensional measurement of micrometer-scale structure is presented.

  12. The differential emission measure of dynamic coronal loops

    NASA Technical Reports Server (NTRS)

    Antiochos, S. K.

    1981-01-01

    The effects of time dependent phenomena, such as flare energization and decay, on the temperature and density structure of the transition region and, in particular, on the form of the differential emission measure are studied. It is found that unlike the case of the static models, the form of the differential emission measure can be used to determine the important physical mechanisms in the dynamic models.

  13. Dynamic Calibration and Verification Device of Measurement System for Dynamic Characteristic Coefficients of Sliding Bearing.

    PubMed

    Chen, Runlin; Wei, Yangyang; Shi, Zhaoyang; Yuan, Xiaoyang

    2016-01-01

    The identification accuracy of dynamic characteristics coefficients is difficult to guarantee because of the errors of the measurement system itself. A novel dynamic calibration method of measurement system for dynamic characteristics coefficients is proposed in this paper to eliminate the errors of the measurement system itself. Compared with the calibration method of suspension quality, this novel calibration method is different because the verification device is a spring-mass system, which can simulate the dynamic characteristics of sliding bearing. The verification device is built, and the calibration experiment is implemented in a wide frequency range, in which the bearing stiffness is simulated by the disc springs. The experimental results show that the amplitude errors of this measurement system are small in the frequency range of 10 Hz-100 Hz, and the phase errors increase along with the increasing of frequency. It is preliminarily verified by the simulated experiment of dynamic characteristics coefficients identification in the frequency range of 10 Hz-30 Hz that the calibration data in this frequency range can support the dynamic characteristics test of sliding bearing in this frequency range well. The bearing experiments in greater frequency ranges need higher manufacturing and installation precision of calibration device. Besides, the processes of calibration experiments should be improved. PMID:27483283

  14. Dynamic Calibration and Verification Device of Measurement System for Dynamic Characteristic Coefficients of Sliding Bearing

    PubMed Central

    Chen, Runlin; Wei, Yangyang; Shi, Zhaoyang; Yuan, Xiaoyang

    2016-01-01

    The identification accuracy of dynamic characteristics coefficients is difficult to guarantee because of the errors of the measurement system itself. A novel dynamic calibration method of measurement system for dynamic characteristics coefficients is proposed in this paper to eliminate the errors of the measurement system itself. Compared with the calibration method of suspension quality, this novel calibration method is different because the verification device is a spring-mass system, which can simulate the dynamic characteristics of sliding bearing. The verification device is built, and the calibration experiment is implemented in a wide frequency range, in which the bearing stiffness is simulated by the disc springs. The experimental results show that the amplitude errors of this measurement system are small in the frequency range of 10 Hz–100 Hz, and the phase errors increase along with the increasing of frequency. It is preliminarily verified by the simulated experiment of dynamic characteristics coefficients identification in the frequency range of 10 Hz–30 Hz that the calibration data in this frequency range can support the dynamic characteristics test of sliding bearing in this frequency range well. The bearing experiments in greater frequency ranges need higher manufacturing and installation precision of calibration device. Besides, the processes of calibration experiments should be improved. PMID:27483283

  15. A Dynamic Measurement of Consensus in Small Decision Making Groups.

    ERIC Educational Resources Information Center

    Spillman, Bonnie; And Others

    A new method for the measurement of consensus in small groups is proposed. The method allows for the study of the dynamic formation of consensus and, with the aid of some mathematical manipulations, reveals the development of subgroup relations over time. In a pilot test, the method was used to study groups of students choosing a topic which they…

  16. Dynamic measurements of gear tooth friction and load

    NASA Technical Reports Server (NTRS)

    Rebbechi, Brian; Oswald, Fred B.; Townsend, Dennis P.

    1991-01-01

    As part of a program to study fundamental mechanisms of gear noise, static and dynamic gear tooth strain measurements were made on the NASA gear-noise rig. Tooth-fillet strains from low-contact ratio-spur gears were recorded for 28 operating conditions. A method is introduced whereby strain gage measurements taken from both the tension and compression sides of a gear tooth can be transformed into the normal and frictional loads on the tooth. This technique was applied to both the static and dynamic strain data. The static case results showed close agreement with expected results. For the dynamic case, the normal-force computation produced very good results, but the friction results, although promising, were not as accurate. Tooth sliding friction strongly affected the signal from the strain gage on the tensionside of the tooth. The compression gage was affected by friction to a much lesser degree. The potential of the method to measure friction force was demonstrated, but further refinement will be required before this technique can be used to measure friction forces dynamically with an acceptable degree of accuracy.

  17. Deciphering Jupiter's atmospheric dynamics using the upcoming Juno gravity measurements

    NASA Astrophysics Data System (ADS)

    Kaspi, Yohai; Galanti, Eli

    2016-07-01

    This summer, the Juno spacecraft will arrive at Jupiter in course for close flybys of the planet, obtaining a high precision gravity spectrum of Jupiter. This data can be used to estimate the depth of Jupiter's observed cloud-level wind, and decipher the possible internal flows, that might be decoupled from the surface wind. In this talk, we discuss the Juno gravity experiment, and the possible outcomes with regard to the flows on Jupiter. We show several ways in which the gravity spectrum might be used to study the large scale flows: 1. measurements of the high order even harmonics which beyond J10 are dominated by the dynamics; 2. measurements of odd gravity harmonics which have no contribution from a static planet, and therefore are a pure signature of dynamics; 3. upper limits on the depth of the surface flow can be obtained by comparing low order even harmonics from dynamical models to the difference between the measured low order even harmonics and the largest possible values of a static planet; 4. direct latitudinally varying measurements of the gravity field exerted on the spacecraft. We will discuss how these methods may be applied given the expected sensitivities of the Juno gravity experiment. In addition, we present an inverse adjoint model, which allows given the gravity data, to infer the flows that produce it. This will allow, hopefully, to make significant progress in one of the longest-standing question in planetary atmospheric dynamics regarding the nature of the flows on the giant planets.

  18. The Dynamic Personality Inventory: What Does It Measure?

    ERIC Educational Resources Information Center

    Kline, Paul; Storey, Ron

    1978-01-01

    The Dynamic Personality Inventory purports to measure the tendencies, sublimations, reaction-formations, and defence mechanisms associated with the various patterns of psychosexual development and contains 33 scales, constructed from factor analyses of inter-item correlations, of high reliability. This study attempts to determine its validity,…

  19. Coordinated analysis of airborne spectrophotometric measurements from the mid-day auroras

    NASA Technical Reports Server (NTRS)

    Sivjee, G. G.

    1974-01-01

    Measurements made in the midday auroras are analyzed and compared to measurements from the nighttime auroras. The auroral emission features in the UV spectrum, the N2(+)ING, the N22PG, and N2VK bands, are discussed. Spectral profiles of different bands are presented, and intensity distributions are obtained. Three mechanisms are suggested which can account for the marked differences between the intensity distributions of the N2(+)ING bands of the high altitude midday auroras and the low altitude nighttime auroras: (1) differences in vibrational, rotational, and transitional temperatures; (2) resonant scattering of solar radiation; and (3) excitation of slow ions.

  20. In-flight measurement of upwind dynamic soaring in albatrosses

    NASA Astrophysics Data System (ADS)

    Sachs, Gottfried

    2016-03-01

    In-flight measurement results on upwind flight of albatrosses using dynamic soaring are presented. It is shown how the birds manage to make progress against the wind on the basis of small-scale dynamic soaring maneuvers. For this purpose, trajectory features, motion quantities and mechanical energy relationships as well as force characteristics are analyzed. The movement on a large-scale basis consists of a tacking type flight technique which is composed of dynamic soaring cycle sequences with alternating orientation to the left and right. It is shown how this is performed by the birds so that they can achieve a net upwind flight without a transversal large-scale movement and how this compares with downwind or across wind flight. Results on upwind dynamic soaring are presented for low and high wind speed cases. It is quantified how much the tacking trajectory length is increased when compared with the beeline distance. The presented results which are based on in-flight measurements of free flying albatrosses were achieved with an in-house developed GPS-signal tracking method yielding the required high precision for the small-scale dynamic soaring flight maneuvers.

  1. Movement order and saccade direction affect a common measure of eye-hand coordination in bimanual reaching

    PubMed Central

    Wang, Cunguo; Ferdoash, Afreen; Snyder, Lawrence H.

    2014-01-01

    Studies of visually guided unimanual reaching have established that a saccade usually precedes each reach and that the reaction times (RTs) for the saccade and reach are highly correlated. The correlation of eye and hand RT is commonly taken as a measure of eye-hand coordination and is thought to assist visuospatial guidance of the hand. We asked what happens during a bimanual reach task. As with a unimanual reach, a saccade was executed first. Although latencies were fastest on unimanual trials, eye and hand RT correlation was identical whether just one or both hands reached to a single target. The average correlation was significantly reduced, however, when each hand reached simultaneously to a different target. We considered three factors that might explain the drop. We found that correlation strength depended on which hand reached first and on which hand reached to the same target as the saccade. Surprisingly, these two factors were largely independent, and the identity of the hand, left or right, had little effect. Eye-hand correlation was similar to that seen with unimanual reaching only when the hand that moved to the same target as the saccade was also the first hand to move. Thus both timing as well as spatial pattern are important in determining eye-hand coordination. PMID:24848462

  2. Direct measurements of the coordination of lever arm swing and the catalytic cycle in myosin V.

    PubMed

    Trivedi, Darshan V; Muretta, Joseph M; Swenson, Anja M; Davis, Jonathon P; Thomas, David D; Yengo, Christopher M

    2015-11-24

    Myosins use a conserved structural mechanism to convert the energy from ATP hydrolysis into a large swing of the force-generating lever arm. The precise timing of the lever arm movement with respect to the steps in the actomyosin ATPase cycle has not been determined. We have developed a FRET system in myosin V that uses three donor-acceptor pairs to examine the kinetics of lever arm swing during the recovery and power stroke phases of the ATPase cycle. During the recovery stroke the lever arm swing is tightly coupled to priming the active site for ATP hydrolysis. The lever arm swing during the power stroke occurs in two steps, a fast step that occurs before phosphate release and a slow step that occurs before ADP release. Time-resolved FRET demonstrates a 20-Å change in distance between the pre- and postpower stroke states and shows that the lever arm is more dynamic in the postpower stroke state. Our results suggest myosin binding to actin in the ADP.Pi complex triggers a rapid power stroke that gates the release of phosphate, whereas a second slower power stroke may be important for mediating strain sensitivity.

  3. Direct measurements of the coordination of lever arm swing and the catalytic cycle in myosin V

    PubMed Central

    Trivedi, Darshan V.; Muretta, Joseph M.; Swenson, Anja M.; Davis, Jonathon P.; Thomas, David D.; Yengo, Christopher M.

    2015-01-01

    Myosins use a conserved structural mechanism to convert the energy from ATP hydrolysis into a large swing of the force-generating lever arm. The precise timing of the lever arm movement with respect to the steps in the actomyosin ATPase cycle has not been determined. We have developed a FRET system in myosin V that uses three donor–acceptor pairs to examine the kinetics of lever arm swing during the recovery and power stroke phases of the ATPase cycle. During the recovery stroke the lever arm swing is tightly coupled to priming the active site for ATP hydrolysis. The lever arm swing during the power stroke occurs in two steps, a fast step that occurs before phosphate release and a slow step that occurs before ADP release. Time-resolved FRET demonstrates a 20-Å change in distance between the pre- and postpower stroke states and shows that the lever arm is more dynamic in the postpower stroke state. Our results suggest myosin binding to actin in the ADP.Pi complex triggers a rapid power stroke that gates the release of phosphate, whereas a second slower power stroke may be important for mediating strain sensitivity. PMID:26553992

  4. Analysis of in situ measurements of cirrus anvil outflow dynamics

    NASA Astrophysics Data System (ADS)

    Lederman, J. I.; Whiteway, J. A.

    2012-12-01

    The airborne campaign, EMERALD 2 (Egrett Microphysics Experiment with Radiation, Lidar, and Dynamics,) was conducted out of Darwin, Australia in 2002. Objectives included characterization of the dynamics in the cirrus anvil outflow from tropical deep convection. Two aircraft, the Egrett and King Air, were flown in tandem in the upper troposphere (7 km - 15 km) to collect in situ measurements in the anvil outflow from a storm named "Hector" that occurs on a regular basis over the Tiwi Islands north of Darwin during November and December. Turbulence probes mounted on the wings of the Egrett aircraft were used to measure the wind fluctuations across the anvil and along its length with a spatial resolution of 2 meters. The in situ measurements from the Egrett were coincident with lidar measurements of the cloud structure from the King Air aircraft flying directly below. The presentation will show results of the analysis of the measurements with an emphasis on the turbulence, gravity waves, and coherent structures that are particular to the cirrus anvil outflow environment. Emphasis is placed on the dynamics associated with the generation of mammatus formations at the base of the anvil clouds.

  5. Atmospheric Radiation Measurements Aerosol Intensive Operating Period: Comparison of Aerosol Scattering during Coordinated Flights

    NASA Technical Reports Server (NTRS)

    Hallar, A. G.; Strawa, A. W.; Schmid, B.; Andrews, E.; Ogren, J.; Sheridan, P.; Ferrare, R.; Covert, D.; Elleman, R.; Jonsson, H.; Bokarius, K.; Luu, A.

    2006-01-01

    In May 2003, a Twin Otter airplane, equipped with instruments for making in situ measurements of aerosol optical properties, was deployed during the Atmospheric Radiation Measurements (ARM) Program s Aerosol Intensive Operational Period in Oklahoma. Several of the Twin Otter flights were flown in formation with an instrumented light aircraft (Cessna 172XP) that makes routine in situ aerosol profile flights over the site. This paper presents comparisons of measured scattering coefficients at 467 nm, 530 nm, and 675 nm between identical commercial nephelometers aboard each aircraft. Overall, the agreement between the two nephelometers decreases with longer wavelength. During the majority of the flights, the Twin Otter flew with a diffuser inlet while the Cessna had a 1 mm impactor, allowing for an estimation of the fine mode fraction aloft. The fine mode fraction aloft was then compared to the results of a ground-based nephelometer. Comparisons are also provided in which both nephelometers operated with identical 1 mm impactors. These scattering coefficient comparisons are favorable at the longer wavelengths (i.e., 530 nm and 675 nm), yet differed by approximately 30% at 467 nm. Mie scattering calculations were performed using size distribution measurements, made during the level flight legs. Results are also presented from Cadenza, a new continuous wave cavity ring-down (CW-CRD) instrument, which compared favorably (i.e., agreed within 2%) with data from other instruments aboard the Twin Otter. With this paper, we highlight the significant implications of coarse mode (larger than 1 mm) aerosol aloft with respect to aerosol optical properties.

  6. Measurements of nuclear spin dynamics by spin-noise spectroscopy

    SciTech Connect

    Ryzhov, I. I.; Poltavtsev, S. V.; Kozlov, G. G.; Zapasskii, V. S.; Kavokin, K. V.; Glazov, M. M.; Vladimirova, M.; Scalbert, D.; Cronenberger, S.; Lemaître, A.; Bloch, J.

    2015-06-15

    We exploit the potential of the spin noise spectroscopy (SNS) for studies of nuclear spin dynamics in n-GaAs. The SNS experiments were performed on bulk n-type GaAs layers embedded into a high-finesse microcavity at negative detuning. In our experiments, nuclear spin polarisation initially prepared by optical pumping is monitored in real time via a shift of the peak position in the electron spin noise spectrum. We demonstrate that this shift is a direct measure of the Overhauser field acting on the electron spin. The dynamics of nuclear spin is shown to be strongly dependent on the electron concentration.

  7. Multiple Point Dynamic Gas Density Measurements Using Molecular Rayleigh Scattering

    NASA Technical Reports Server (NTRS)

    Seasholtz, Richard; Panda, Jayanta

    1999-01-01

    A nonintrusive technique for measuring dynamic gas density properties is described. Molecular Rayleigh scattering is used to measure the time-history of gas density simultaneously at eight spatial locations at a 50 kHz sampling rate. The data are analyzed using the Welch method of modified periodograms to reduce measurement uncertainty. Cross-correlations, power spectral density functions, cross-spectral density functions, and coherence functions may be obtained from the data. The technique is demonstrated using low speed co-flowing jets with a heated inner jet.

  8. Coordinated ground and space measurements of an auroral surge over South Pole

    SciTech Connect

    Rosenberg, T.J.; Detrick, D.L.; Mizera, P.F.; Gorney, D.J.; Berkey, F.T.; Eather, R.H.; Lanzerotti, L.J.

    1987-10-01

    Coincident ground-based and satellite observations are presented of a premidnight auroral surge over Amundsen-Scott South Pole station. The set of near-simultaneous measurements provides an excellent opportunity to gain a more quantitative understanding of the nature of premidnight substorm activity at high geomagnetic latitudes. The surge produced a rapid onset of cosmic radio noise absorption at the station. On the polar-orbiting DMSP F6 spacecraft, intense X ray emissions with E>2 keV energy were imaged 1/sup 0/ to 2/sup 0/ magnetically equatorward of South Pole approximately 1 min prior to the peak of the absorption event. The spectrum of precipitating electrons determined from the X ray measurements could be characterized by an e-folding energy of approx.11 keV and is found to be adequate to account for the cosmic noise absorption and maximum auroral luminosity recorded at South Pole. Photometer, all-sky camera, riometer, and magnetometer data are used to estimate the velocity of motion and spatial extent of the auroral precipitation and the ionospheric currents associated with the surge. The electron precipitation region is deduced to have a latitudinal scale size of <100 km and to move poleward with a speed of approx.1--2 km/s coincident with the movement of a westward electrojet.

  9. Real-Time Dynamics Monitoring System with Synchronized Phasor Measurements

    2005-01-01

    The Real-Time Dynamics Monitoring System is designed to monitor the dynamics within the power grid and assess the system behavior during normal and disturbance conditions. The RTDMS application was built on the Grid-3P technology platform and takes real-time information collected by Synchronized Phasor Measurement Units (PMU5) or other collection devices and transmitted to a central Phasor Data Concentrator (PDC) for monitoring grid dynamics. The data is sampled 30 times per second and is time-synchronized. Thismore » data is processed to create graphical and geographical displays to provide visualization for frequency/frequency response, voltage magnitudes and angles, voltage angle differences across critical paths as well as real and reactive power-flows on a sub-second and second basis. Software allows for monitoring, tracking, historical data archiving and electric system troubleshooting for reliability management.« less

  10. Introducing variable-step topography (VST) coordinates within dynamically constrained nonhydrostatic modeling system (NMS). Part 2: VST performance on orthodox obstacle flows

    NASA Astrophysics Data System (ADS)

    Tripoli, Gregory J.; Smith, Eric A.

    2014-06-01

    In this second part of a two-part sequence of papers, the performance metrics and quantitative advantages of a new VST surface coordinate system, implemented within a dynamically constrained, nonhydrostatic, cloud mesoscale atmospheric model, are evaluated in conjunction with seven orthodox obstacle flow problems. [The first part presented a full formulation of the VST model, prefaced by a description of the framework of the newly re-tooled nonhydrostatic modeling system (NMS) operating within integral constraints based on the conservation of the foremost quantities of mass, energy and circulation.] The intent behind VST is to create a vertical surface coordinate system boundary underpinning a nonhydrostatic atmosphere capable of reliable simulations of flows over both smooth and steep terrain without sacrificing dynamical integrity over either type of surface. Model simulation results are analyzed for six classical fluid dynamics problems involving flows relative to obstacles with known analytical or laboratory-simulated solutions, as well as for a seventh noteworthy mountain wave breaking problem that has well-studied numerical solutions. For cases when topography becomes excessively severe or poorly resolved numerically, atmospheric models using transform (terrain-following) coordinates produce noteworthy errors rendering a stable integration only if the topography is smoothed. For cases when topography is slowly varying (smooth or subtle), models using discrete-step coordinates also produce noteworthy errors relative to known solutions. Alternatively, the VST model demonstrates that both limitations of the two conventional approaches, for the entire range of slope severities, can be overcome. This means that VST is ideally suited for a scalable, nonhydrostatic atmospheric model, safeguarded with physically realistic dynamical constraints.

  11. Large-Scale Hybrid Dynamic Simulation Employing Field Measurements

    SciTech Connect

    Huang, Zhenyu; Guttromson, Ross T.; Hauer, John F.

    2004-06-30

    Simulation and measurements are two primary ways for power engineers to gain understanding of system behaviors and thus accomplish tasks in system planning and operation. Many well-developed simulation tools are available in today's market. On the other hand, large amount of measured data can be obtained from traditional SCADA systems and currently fast growing phasor networks. However, simulation and measurement are still two separate worlds. There is a need to combine the advantages of simulation and measurements. In view of this, this paper proposes the concept of hybrid dynamic simulation which opens up traditional simulation by providing entries for measurements. A method is presented to implement hybrid simulation with PSLF/PSDS. Test studies show the validity of the proposed hybrid simulation method. Applications of such hybrid simulation include system event playback, model validation, and software validation.

  12. A Dynamic Attitude Measurement System Based on LINS

    PubMed Central

    Li, Hanzhou; Pan, Quan; Wang, Xiaoxu; Zhang, Juanni; Li, Jiang; Jiang, Xiangjun

    2014-01-01

    A dynamic attitude measurement system (DAMS) is developed based on a laser inertial navigation system (LINS). Three factors of the dynamic attitude measurement error using LINS are analyzed: dynamic error, time synchronization and phase lag. An optimal coning errors compensation algorithm is used to reduce coning errors, and two-axis wobbling verification experiments are presented in the paper. The tests indicate that the attitude accuracy is improved 2-fold by the algorithm. In order to decrease coning errors further, the attitude updating frequency is improved from 200 Hz to 2000 Hz. At the same time, a novel finite impulse response (FIR) filter with three notches is designed to filter the dither frequency of the ring laser gyro (RLG). The comparison tests suggest that the new filter is five times more effective than the old one. The paper indicates that phase-frequency characteristics of FIR filter and first-order holder of navigation computer constitute the main sources of phase lag in LINS. A formula to calculate the LINS attitude phase lag is introduced in the paper. The expressions of dynamic attitude errors induced by phase lag are derived. The paper proposes a novel synchronization mechanism that is able to simultaneously solve the problems of dynamic test synchronization and phase compensation. A single-axis turntable and a laser interferometer are applied to verify the synchronization mechanism. The experiments results show that the theoretically calculated values of phase lag and attitude error induced by phase lag can both match perfectly with testing data. The block diagram of DAMS and physical photos are presented in the paper. The final experiments demonstrate that the real-time attitude measurement accuracy of DAMS can reach up to 20″ (1σ) and the synchronization error is less than 0.2 ms on the condition of three axes wobbling for 10 min. PMID:25177802

  13. A dynamic attitude measurement system based on LINS.

    PubMed

    Li, Hanzhou; Pan, Quan; Wang, Xiaoxu; Zhang, Juanni; Li, Jiang; Jiang, Xiangjun

    2014-01-01

    A dynamic attitude measurement system (DAMS) is developed based on a laser inertial navigation system (LINS). Three factors of the dynamic attitude measurement error using LINS are analyzed: dynamic error, time synchronization and phase lag. An optimal coning errors compensation algorithm is used to reduce coning errors, and two-axis wobbling verification experiments are presented in the paper. The tests indicate that the attitude accuracy is improved 2-fold by the algorithm. In order to decrease coning errors further, the attitude updating frequency is improved from 200 Hz to 2000 Hz. At the same time, a novel finite impulse response (FIR) filter with three notches is designed to filter the dither frequency of the ring laser gyro (RLG). The comparison tests suggest that the new filter is five times more effective than the old one. The paper indicates that phase-frequency characteristics of FIR filter and first-order holder of navigation computer constitute the main sources of phase lag in LINS. A formula to calculate the LINS attitude phase lag is introduced in the paper. The expressions of dynamic attitude errors induced by phase lag are derived. The paper proposes a novel synchronization mechanism that is able to simultaneously solve the problems of dynamic test synchronization and phase compensation. A single-axis turntable and a laser interferometer are applied to verify the synchronization mechanism. The experiments results show that the theoretically calculated values of phase lag and attitude error induced by phase lag can both match perfectly with testing data. The block diagram of DAMS and physical photos are presented in the paper. The final experiments demonstrate that the real-time attitude measurement accuracy of DAMS can reach up to 20″ (1σ) and the synchronization error is less than 0.2 ms on the condition of three axes wobbling for 10 min. PMID:25177802

  14. Understanding social motor coordination.

    PubMed

    Schmidt, R C; Fitzpatrick, Paula; Caron, Robert; Mergeche, Joanna

    2011-10-01

    Recently there has been much interest in social coordination of motor movements, or as it is referred to by some researchers, joint action. This paper reviews the cognitive perspective's common coding/mirror neuron theory of joint action, describes some of its limitations and then presents the behavioral dynamics perspective as an alternative way of understanding social motor coordination. In particular, behavioral dynamics' ability to explain the temporal coordination of interacting individuals is detailed. Two experiments are then described that demonstrate how dynamical processes of synchronization are apparent in the coordination underlying everyday joint actions such as martial art exercises, hand-clapping games, and conversations. The import of this evidence is that emergent dynamic patterns such as synchronization are the behavioral order that any neural substrate supporting joint action (e.g., mirror systems) would have to sustain.

  15. Identification of dynamic properties from ambient vibration measurements

    SciTech Connect

    Farrar, C.R.; James, G.H. III

    1995-09-01

    To better understand the dynamic behavior of structures under normal dynamic loads as well as extreme loads such as those caused by seismic events or high winds, it is desirable to measure the dynamic properties (resonant frequencies, mode shapes and modal damping) of these structures. The cross-correlation function between two response measurements made on an ambiently excited structure is shown to have the same form as the system`s impulse response function. Therefore, standard time-domain curve-fitting procedures such as the complex exponential method, which are typically applied to impulse response functions, can now be applied to the cross-correlation functions to estimate the resonant frequencies and modal damping of the structure. A direct comparison of resonant frequencies identified by curve-fitting the cross-correlation functions, using traffic excitation as the ambient vibration source, and modal properties identified by standard forced vibration testing of a highway bridge, after traffic was removed, showed a maximum discrepancy of 3.63%. Similar comparisons for the average modal damping values identified by the two methods showed a 9.82% difference. This experimental verification implies that the proposed method of analyzing ambient vibration data has the potential to accurately assess the dynamic properties of large structures subjected to seismic excitations and small structures that are tested on a shake table.

  16. Investigating dynamical complexity of geomagnetic jerks using various entropy measures

    NASA Astrophysics Data System (ADS)

    Balasis, Georgios; Potirakis, Stelios; Mandea, Mioara

    2016-06-01

    Recently, many novel concepts originated in dynamical systems or information theory have been developed, partly motivated by specific research questions linked to geosciences, and found a variety of different applications. This continuously extending toolbox of nonlinear time series analysis highlights the importance of the dynamical complexity to understand the behavior of the complex Earth's system and its components. Here, we propose to apply such new approaches, mainly a series of entropy methods to the time series of the geomagnetic field. Two datasets provided by Chambon la Foret (France) and Niemegk (Germany) observatories are considered for analysis to detect dynamical complexity changes associated with geomagnetic jerks, the abrupt changes in the second temporal derivative of the Earth's magnetic field. The results clearly demonstrate the ability of Shannon and Tsallis entropies as well as Fisher information to detect events in a regional manner having identified complexities lower than the background in time intervals when geomagnetic jerks have already been reported in the literature. Additionally, these information measures are directly applicable to the original data without having to derive the secular variation or acceleration from the observatory monthly means. The strength of the proposed analysis to reveal dynamical complexity features associated with geomagnetic jerks can be utilized for analyzing not only ground measurements, but also satellite data, as those provided by the current magnetic field mission of Swarm.

  17. Enhanced crosslimb transfer of force-field learning for dynamics that are identical in extrinsic and joint-based coordinates for both limbs.

    PubMed

    Carroll, Timothy J; de Rugy, Aymar; Howard, Ian S; Ingram, James N; Wolpert, Daniel M

    2016-01-01

    Humans are able to adapt their motor commands to make accurate movements in novel sensorimotor environments, such as when wielding tools that alter limb dynamics. However, it is unclear to what extent sensorimotor representations, obtained through experience with one limb, are available to the opposite, untrained limb and in which form they are available. Here, we compared crosslimb transfer of force-field compensation after participants adapted to a velocity-dependent curl field, oriented either in the sagittal or the transverse plane. Due to the mirror symmetry of the limbs, the force field had identical effects for both limbs in joint and extrinsic coordinates in the sagittal plane but conflicting joint-based effects in the transverse plane. The degree of force-field compensation exhibited by the opposite arm in probe trials immediately after initial learning was significantly greater after sagittal (26 ± 5%) than transverse plane adaptation (9 ± 4%; P < 0.001), irrespective of whether participants learned initially with the left or the right arm or via abrupt or gradual exposure to the force field. Thus transfer was impaired when the orientation of imposed dynamics conflicted in intrinsic coordinates for the two limbs. The data reveal that neural representations of novel dynamics are only partially available to the opposite limb, since transfer is incomplete even when force-field perturbation is spatially compatible for the two limbs, according to both intrinsic and extrinsic coordinates.

  18. Enhanced crosslimb transfer of force-field learning for dynamics that are identical in extrinsic and joint-based coordinates for both limbs

    PubMed Central

    de Rugy, Aymar; Howard, Ian S.; Ingram, James N.; Wolpert, Daniel M.

    2015-01-01

    Humans are able to adapt their motor commands to make accurate movements in novel sensorimotor environments, such as when wielding tools that alter limb dynamics. However, it is unclear to what extent sensorimotor representations, obtained through experience with one limb, are available to the opposite, untrained limb and in which form they are available. Here, we compared crosslimb transfer of force-field compensation after participants adapted to a velocity-dependent curl field, oriented either in the sagittal or the transverse plane. Due to the mirror symmetry of the limbs, the force field had identical effects for both limbs in joint and extrinsic coordinates in the sagittal plane but conflicting joint-based effects in the transverse plane. The degree of force-field compensation exhibited by the opposite arm in probe trials immediately after initial learning was significantly greater after sagittal (26 ± 5%) than transverse plane adaptation (9 ± 4%; P < 0.001), irrespective of whether participants learned initially with the left or the right arm or via abrupt or gradual exposure to the force field. Thus transfer was impaired when the orientation of imposed dynamics conflicted in intrinsic coordinates for the two limbs. The data reveal that neural representations of novel dynamics are only partially available to the opposite limb, since transfer is incomplete even when force-field perturbation is spatially compatible for the two limbs, according to both intrinsic and extrinsic coordinates. PMID:26581867

  19. Dynamic distortions in the HARP TPC: observations, measurements, modelling and corrections

    NASA Astrophysics Data System (ADS)

    Bagulya, A.; Blondel, A.; Borghi, S.; Catanesi, G.; Chimenti, P.; Gastaldi, U.; Giani, S.; Grichine, V.; Ivanchenko, V.; Kolev, D.; Panman, J.; Radicioni, E.; Tsenov, R.; Tsukerman, I.

    2009-11-01

    The HARP experiment was designed to study hadron production in proton-nucleus collisions in the energy range of 1.5 GeV/c-15 GeV/c. The experiment was made of two spectrometers, a forward dipole spectrometer and a large-angle solenoid spectrometer. In the large-angle spectrometer the main tracking and particle identification is performed by a cylindrical Time Projection Chamber (TPC) which suffered a number of shortcomings later addressed in the analysis. In this paper we discuss the effects of time-dependent (dynamic) distortions of the position measurements in the TPC which are due to a build-up of ion charges in the chamber during the accelerator spill. These phenomena have been studied both by modelling and by experiment, and a correction procedure has been developed. The effects of the time-dependent distortions have been measured experimentally by means of recoil protons in elastic scattering reactions, where the track coordinates are precisely predictable from simple kinematical considerations. The dynamics of the positive ion cloud and of the electrostatics of the field-cage system have been modelled with a phenomenological approach providing an understanding of the features. Using the elastic scattering data a general correction procedure has been developed and applied to all data settings. After application of the corrections for dynamic distortions the corrected data have a performance equal to data where the dynamic distortions are absent. We describe the phenomenological model, the comparison with the measurements, the distortion correction method and the results obtained with experimental data.

  20. A segmental calibration method for a miniature serial-link coordinate measuring machine using a compound calibration artefact

    NASA Astrophysics Data System (ADS)

    Zhou, Awei; Guo, Junjie; Shao, Wei; Li, Beizhan

    2013-06-01

    In the application of a miniature serial-link coordinate measuring machine, it is necessary to calibrate the structural parameters and improve the positioning accuracy for accurate task performance. In this study, using a designed compound calibration artefact, a new calibration method which includes kinematic calibration and laser tool centre point (TCP) calibration is proposed. In the kinematic calibration, geometric parameters included in the kinematic model can be identified by using the constraint that the cone angle or cylinder diameter for several different positions is invariable. For the laser TCP calibration, the relative positions between the laser sensor and the end effector are calibrated by means of the cone surface part of the calibration artefact, using the constraint that the conic node positions for several different measurements are invariable. During the calibration process, the identification of all structural parameters from measuring data can be separated furthest, so the calibration errors brought by strong correlations between all the parameters can be decreased. Moreover, the differences of different positions of end effector in calculations can be used; thus, the calibration error which is due to the positioning error of the end effector can be decreased. Experimental results on real data have demonstrated the effectiveness of our method.

  1. ICET - International Collaboration on Experiments in Turbulence: Coordinated Measurements in High Reynolds Number Turbulent Boundary Layers from Three Wind Tunnels

    NASA Astrophysics Data System (ADS)

    Nagib, H.; Smits, A.; Marusic, I.; Alfredsson, P. H.

    2009-11-01

    Zero pressure gradient (ZPG) boundary layers are one of the canonical, wall-bounded, turbulent flows that have been the focus of experimental and analytical investigations for several decades. Over the past few years, four groups have focused on systematic comparison between several measurement techniques and three facilities. Two closed return wind tunnels with ZPG boundary layers developed on a plate suspended near the mid-height of the test section (at KTH and IIT), and an open return facility with a large and long test section and a boundary layer developing along its floor (at the University of Melbourne), are used for these coordinated efforts. The development length of the boundary layers and the free-stream velocity in the three facilities range from 5.5 to 22 m, and from 10 to 60 m/s, respectively. Various arrangements for adjustable test section ceilings are employed to generate ZPG boundary layers over the range of momentum thickness Reynolds numbers from 11,000 to 70,000. Oil film interferometry (OFI) is employed to directly measure the wall shear stress, and various sizes of Pitot probes and types of hot-wire sensors are used to measure wall-normal velocity profiles at different locations and free-stream velocities. Mean velocity, turbulence statistics and integral parameters are examined.

  2. Measuring contemporary crustal motions; NASA’s Crustal Dynamics Project

    USGS Publications Warehouse

    Frey, H. V.; Bosworth, J. M.

    1988-01-01

    In this article we describe briefly the two space geodetic techniques and how they are used by the Crustal Dynamics Project, show some of the very exciting results that have emerged at the halfway point in the project's life, describe the availability and utilization of the data being collected, and consider what the future may hold when measurement accuracies eventually exceed even those now available and when other international groups become more heavily involved.   

  3. Plasma crystal dynamics measured with a three-dimensional plenoptic camera.

    PubMed

    Jambor, M; Nosenko, V; Zhdanov, S K; Thomas, H M

    2016-03-01

    Three-dimensional (3D) imaging of a single-layer plasma crystal was performed using a commercial plenoptic camera. To enhance the out-of-plane oscillations of particles in the crystal, the mode-coupling instability (MCI) was triggered in it by lowering the discharge power below a threshold. 3D coordinates of all particles in the crystal were extracted from the recorded videos. All three fundamental wave modes of the plasma crystal were calculated from these data. In the out-of-plane spectrum, only the MCI-induced hot spots (corresponding to the unstable hybrid mode) were resolved. The results are in agreement with theory and show that plenoptic cameras can be used to measure the 3D dynamics of plasma crystals.

  4. Plasma crystal dynamics measured with a three-dimensional plenoptic camera.

    PubMed

    Jambor, M; Nosenko, V; Zhdanov, S K; Thomas, H M

    2016-03-01

    Three-dimensional (3D) imaging of a single-layer plasma crystal was performed using a commercial plenoptic camera. To enhance the out-of-plane oscillations of particles in the crystal, the mode-coupling instability (MCI) was triggered in it by lowering the discharge power below a threshold. 3D coordinates of all particles in the crystal were extracted from the recorded videos. All three fundamental wave modes of the plasma crystal were calculated from these data. In the out-of-plane spectrum, only the MCI-induced hot spots (corresponding to the unstable hybrid mode) were resolved. The results are in agreement with theory and show that plenoptic cameras can be used to measure the 3D dynamics of plasma crystals. PMID:27036775

  5. Radiating Shock Measurements in the Z-Pinch Dynamic Hohlraum

    SciTech Connect

    Rochau, G. A.; Bailey, J. E.; Chandler, G. A.; Lemke, R. W.; Peterson, K. J.; Slutz, S. A.; Maron, Y.; Fisher, D. V.; Fisher, V. I.; Stambulchik, E.; Dunham, G. S.; MacFarlane, J. J.; Schroen, D. G.

    2008-03-28

    The Z-pinch dynamic hohlraum is an x-ray source for high energy-density physics studies that is heated by a radiating shock to radiation temperatures >200 eV. The time-dependent 300-400 eV electron temperature and 15-35 mg/cc density of this shock have been measured for the first time using space-resolved Si tracer spectroscopy. The shock x-ray emission is inferred from these measurements to exceed 50 TW, delivering >180 kJ to the hohlraum.

  6. A new method of dynamic multitarget tracking and measuring

    NASA Astrophysics Data System (ADS)

    Wang, Fei; Zheng, Nanning; Liu, Yuehu

    2003-09-01

    In allusion to the features of dynamic multi-target tracking and measuring system (DMTTMS), compars the DMTTMS with the single target tracking and measuring system (STTMS) and analyses the difficulties about homonymy image point ascertainment in DMTTMS. Three methods are presented based on the geometric peculiarity of rays in imaging principia of geometric optics to solve the problem of homonymy image point ascertainment. A design scheme of DMTTMS is put forward using multiple optical capture instruments. Furthermore, an algorithm is emphasized that could treat some targets that are hided by other targets. The simulating result shows that proposed scheme and algorithm has feasibility and validity for DMTTMS.

  7. Dynamic modeling of structures from measured complex modes

    NASA Technical Reports Server (NTRS)

    Ibrahim, s. R.

    1982-01-01

    A technique is presented to use a set of identified complex modes together with an analytical mathematical model of a structure under test to compute improved mass, stiffness and damping matrices. A set of identified normal modes, computed from the measured complex modes, is used in the mass orthogonality equation to compute an improved mass matrix. This eliminates possible errors that may result from using approximated complex modes as normal modes. The improved mass matrix, the measured complex modes and the higher analytical modes are then used to compute the improved stiffness and damping matrices. The number of degrees-of-freedom of the improved model is limited to equal the number of elements in the measured modal vectors. A simulated experiment shows considerable improvements, in the system's analytical dynamic model, over the frequency range of the given measured modal information.

  8. Generalized Dynamic Factor Models for Mixed-Measurement Time Series

    PubMed Central

    Cui, Kai; Dunson, David B.

    2013-01-01

    In this article, we propose generalized Bayesian dynamic factor models for jointly modeling mixed-measurement time series. The framework allows mixed-scale measurements associated with each time series, with different measurements having different distributions in the exponential family conditionally on time-varying latent factor(s). Efficient Bayesian computational algorithms are developed for posterior inference on both the latent factors and model parameters, based on a Metropolis Hastings algorithm with adaptive proposals. The algorithm relies on a Greedy Density Kernel Approximation (GDKA) and parameter expansion with latent factor normalization. We tested the framework and algorithms in simulated studies and applied them to the analysis of intertwined credit and recovery risk for Moody’s rated firms from 1982–2008, illustrating the importance of jointly modeling mixed-measurement time series. The article has supplemental materials available online. PMID:24791133

  9. Dynamic vacuum measurement by an optical interferometric technique

    NASA Astrophysics Data System (ADS)

    Mari, Domenico; Bergoglio, Mercede; Pisani, Marco; Zucco, Massimo

    2014-12-01

    A homodyne Michelson interferometer was developed to realize a dynamic vacuum standard. The interferometer measures variation in optical path due to refractive index changes related to the pressure of the gas. The measurement arm of the interferometer is formed by two quasi-parallel mirrors which act as a multiplication set-up to allow an increment of the optical path and consequently of the sensitivity. The interference signal is detected by a high speed camera: starting from the recorded interference pattern, two quadrature regions are identified and analyzed by custom software to obtain the quadrature phase signals. The dynamic vacuum system is mainly composed of a large low-pressure chamber VA (about 800 L) connected by a valve and a replaceable orifice to a high pressure chamber VB of about 2 L, hosting the interferometer. The fast pressure drop from 100 kPa to 100 Pa is obtained by a gas expansion from VB to VA. The velocity of the expansion process can be easily varied by substituting the orifice connecting the two chambers. The response of the system was first tested with a slow process of about 40 s at different gains of the measurement arm of the interferometer. Subsequently, a fast process (< 3 s) was considered and the result of the optical device was compared to the measurements performed by two capacitance diaphragm gauges (133 kPa and 1.33 kPa full scale). The gauges are equipped with special electronics to give each nominal reading every 0.7 ms. The two measurements performed by the dynamic vacuum standard and capacitance diaphragm gauges showed an agreement better than 12%.

  10. Airborne Measurement of Ecosystem Carbon Dynamics over Heterogeneous Landscapes

    NASA Astrophysics Data System (ADS)

    Wade, T. J.; Hill, T. C.; Clement, R.; Moncrieff, J.; Disney, M.; Nichol, C. J.; Williams, M. D.

    2009-12-01

    Terrestrial carbon sinks are currently believed to account for the removal and storage of approximately 25% of anthropogenic carbon emissions from the atmosphere. The processes involved are numerous and complex and many feedbacks are at play. The ability to study the dynamics of different ecosystems at scales meaningful to climatic forcing is essential for understanding the key processes involved and identifying crucial sensitivities and thresholds. Airborne platforms with the requisite instrumentation offer the opportunity to directly measure biological processes and atmospheric structures at scales that are not achievable by ground measurements alone. The current generation of small research aircraft such as the University of Edinburgh’s Diamond HK36TTC ECO Dimona present excellent platforms for measurement of both the atmosphere and terrestrial surface. In this study we present results from airborne CO2/H2O flux measuring campaigns in contrasting climatic systems to quantify spatial patterns in ecosystem photosynthesis. Several airborne campaigns were undertaken in Arctic Finland, as part of the Arctic Biosphere Atmosphere Coupling at Multiple Scales (ABACUS) project (2008), and mainland UK as part of the UK Population Biology Network (UKPopNet) 2009 project, to explore the variability in surface CO2 flux across spatial scales larger than captured using conventional ground based eddy covariance. We discuss the application of our aircraft platform as a tool to address the challenge of understanding carbon dynamics within landscapes of heterogeneous vegetation class, terrain and hydrology using complementary datasets acquired from airborne eddy covariance and remote sensing.

  11. Accurate measurements of dynamics and reproducibility in small genetic networks

    PubMed Central

    Dubuis, Julien O; Samanta, Reba; Gregor, Thomas

    2013-01-01

    Quantification of gene expression has become a central tool for understanding genetic networks. In many systems, the only viable way to measure protein levels is by immunofluorescence, which is notorious for its limited accuracy. Using the early Drosophila embryo as an example, we show that careful identification and control of experimental error allows for highly accurate gene expression measurements. We generated antibodies in different host species, allowing for simultaneous staining of four Drosophila gap genes in individual embryos. Careful error analysis of hundreds of expression profiles reveals that less than ∼20% of the observed embryo-to-embryo fluctuations stem from experimental error. These measurements make it possible to extract not only very accurate mean gene expression profiles but also their naturally occurring fluctuations of biological origin and corresponding cross-correlations. We use this analysis to extract gap gene profile dynamics with ∼1 min accuracy. The combination of these new measurements and analysis techniques reveals a twofold increase in profile reproducibility owing to a collective network dynamics that relays positional accuracy from the maternal gradients to the pair-rule genes. PMID:23340845

  12. Hydro-resistive measurement of dynamic lifting strength.

    PubMed

    Pinder, A D; Grieve, D W

    1997-04-01

    A device is described for measuring strength and power outputs of dynamic vertical lifts between heights of 0.4 and 2.2 m. The device is safe, robust, and easily transportable. It consists of a water-filled tube 2 m high and 200 mm internal diameter. The subject pulls vertically on a handle which is connected with flexible wire rope via a series of pulleys to a piston suspended inside the tube. The piston has holes which can be closed with bungs. The drag force is proportional to the square of the velocity. The constant of proportionality can be chosen over a more than 100-fold range and is independent of temperature. Manual force is measured using a strain gauged cantilever over which the rope passes. Rope movement is monitored with a shaft encoder. These devices are sampled synchronously by an interfaced computer. Velocity and power are derived from the measurements of displacement, time and force. The device is highly accurate. Power measurements are not significantly different on two separate days although repetitions on one day show a warming-up effect. This device allows the study of dynamic lifts ranging from slow, high force, quasi-isokinetic lifts to lifts where high velocities and accelerations occur.

  13. An improved method for dynamic measurement of deflections of the vertical based on the maintenance of attitude reference.

    PubMed

    Dai, Dongkai; Wang, Xingshu; Zhan, Dejun; Huang, Zongsheng

    2014-09-03

    A new method for dynamic measurement of deflections of the vertical (DOV) is proposed in this paper. The integration of an inertial navigation system (INS) and global navigation satellite system (GNSS) is constructed to measure the body's attitude with respect to the astronomical coordinates. Simultaneously, the attitude with respect to the geodetic coordinates is initially measured by a star sensor under quasi-static condition and then maintained by the laser gyroscope unit (LGU), which is composed of three gyroscopes in the INS, when the vehicle travels along survey lines. Deflections of the vertical are calculated by using the difference between the attitudes with respect to the geodetic coordinates and astronomical coordinates. Moreover, an algorithm for removing the trend error of the vertical deflections is developed with the aid of Earth Gravitational Model 2008 (EGM2008). In comparison with traditional methods, the new method required less accurate GNSS, because the dynamic acceleration calculation is avoided. The errors of inertial sensors are well resolved in the INS/GNSS integration, which is implemented by a Rauch-Tung-Striebel (RTS) smoother. In addition, a single-axis indexed INS is adopted to improve the observability of the system errors and to restrain the inertial sensor errors. The proposed method is validated by Monte Carlo simulations. The results show that deflections of the vertical can achieve a precision of better than 1″ for a single survey line. The proposed method can be applied to a gravimetry system based on a ground vehicle or ship with a speed lower than 25 m/s.

  14. Measurements of granular flow dynamics with high speed digital images

    SciTech Connect

    Lee, J.

    1994-12-31

    The flow of granular materials is common to many industrial processes. This dissertation suggests and validates image processing algorithms applied to high speed digital images to measure the dynamics (velocity, temperature and volume fraction) of dry granular solids flowing down an inclined chute under the action of gravity. Glass and acrylic particles have been used as granular solids in the experiment. One technique utilizes block matching for spatially averaged velocity measurements of the glass particles. This technique is compared with the velocity measurement using an optic probe which is a conventional granular flow velocity measurement device. The other technique for measuring the velocities of individual acrylic particles is developed with correspondence using a Hopfield network. This technique first locates the positions of particles with pattern recognition techniques, followed by a clustering technique, which produces point patterns. Also, several techniques are compared for particle recognition: synthetic discriminant function (SDF), minimum average correlation energy (MACE) filter, modified minimum average correlation energy (MMACE) filter and variance normalized correlation. The author proposes an MMACE filter which improves generalization of the MACE filter by adjusting the amount of averaged spectrum of training images in the spectrum whitening stages of the MACE filter. Variance normalized correlation is applied to measure the velocity and temperature of flowing glass particles down the inclined chute. The measurements are taken for the steady and wavy flow and qualitatively compared with a theoretical model of granular flow.

  15. High spatial resolution measurements of ram accelerator gas dynamic phenomena

    NASA Technical Reports Server (NTRS)

    Hinkey, J. B.; Burnham, E. A.; Bruckner, A. P.

    1992-01-01

    High spatial resolution experimental tube wall pressure measurements of ram accelerator gas dynamic phenomena are presented. The projectile resembles the centerbody of a ramjet and travels supersonically through a tube filled with a combustible gaseous mixture, with the tube acting as the outer cowling. Pressure data are recorded as the projectile passes by sensors mounted in the tube wall at various locations along the tube. Data obtained by using a special highly instrumented section of tube has allowed the recording of gas dynamic phenomena with a spatial resolution on the order of one tenth the projectile length. High spatial resolution tube wall pressure data from the three regimes of propulsion studied to date (subdetonative, transdetonative, and superdetonative) are presented and reveal the 3D character of the flowfield induced by projectile fins and the canting of the projectile body relative to the tube wall. Also presented for comparison to the experimental data are calculations made with an inviscid, 3D CFD code.

  16. Vertebral shape: automatic measurement with dynamically sequenced active appearance models.

    PubMed

    Roberts, M G; Cootes, T F; Adams, J E

    2005-01-01

    The shape and appearance of vertebrae on lateral dual x-ray absorptiometry (DXA) scans were statistically modelled. The spine was modelled by a sequence of overlapping triplets of vertebrae, using Active Appearance Models (AAMs). To automate vertebral morphometry, the sequence of trained models was matched to previously unseen scans. The dataset includes a significant number of pathologies. A new dynamic ordering algorithm was assessed for the model fitting sequence, using the best quality of fit achieved by multiple sub-model candidates. The accuracy of the search was improved by dynamically imposing the best quality candidate first. The results confirm the feasibility of substantially automating vertebral morphometry measurements even with fractures or noisy images.

  17. The application of co-ordination dynamics to the analysis of discrete movements using table-tennis as a paradigm skill.

    PubMed

    Sørensen, V; Ingvaldsen, R P; Whiting, H T

    2001-07-01

    The purpose of this experiment was to explore the application of co-ordination dynamics to the analysis of discrete rather than cyclical movements. Subjects, standing in a fixed position, were required to return table-tennis balls delivered to different spatial locations in the direction of a fixed target. This was achieved in condition 1 by systematically scaling, from left to right and vice versa, the 'spatial location' of the ball-identified as a control parameter. In condition 2, the control condition, the spatial location was varied randomly over the same range. The changes between regimes of the stroke co-ordination pattern, defined at two different levels, (1) organisational--forehand or backhand drive. and (2) kinematic-the distance of the bat at ball-bat contact relative to the leading edge of the table, were identified as collective variables, the values of which changed spontaneously at the transition points exposed by the control parameter. The switch between regimes was shown to be dependent upon the direction of scaling, i.e. a hysteresis effect was identified in both conditions. These findings confirm that the conceptual and methodological frameworks of co-ordination dynamics can be applied, appropriately, to the analysis of discrete movements. Moreover, it would seem that control parameter values (spatial location of the ball) do not necessarily have to be scaled in a systematic way in order to produce the required effects. PMID:11471838

  18. Dynamical Scheme for Interferometric Measurements of Full-Counting Statistics

    NASA Astrophysics Data System (ADS)

    Dasenbrook, David; Flindt, Christian

    2016-09-01

    We propose a dynamical scheme for measuring the full-counting statistics in a mesoscopic conductor using an electronic Mach-Zehnder interferometer. The conductor couples capacitively to one arm of the interferometer and causes a phase shift which is proportional to the number of transferred charges. Importantly, the full-counting statistics can be obtained from average current measurements at the outputs of the interferometer. The counting field can be controlled by varying the time delay between two separate voltage signals applied to the conductor and the interferometer, respectively. As a specific application, we consider measuring the entanglement entropy generated by partitioning electrons on a quantum point contact. Our scheme is robust against moderate environmental dephasing and may be realized thanks to recent advances in gigahertz quantum electronics.

  19. Dynamics of gecko locomotion: a force-measuring array to measure 3D reaction forces.

    PubMed

    Dai, Zhendong; Wang, Zhouyi; Ji, Aihong

    2011-03-01

    Measuring the interaction between each foot of an animal and the substrate is one of the most effective ways to understand the dynamics of legged locomotion. Here, a new facility - the force-measuring array (FMA) - was developed and applied to measure 3D reaction forces of geckos on different slope surfaces. The FMA consists of 16 3D sensors with resolution to the mN level. At the same time the locomotion behaviour of geckos freely moving on the FMA was recorded by high speed camera. The reaction forces acting on the gecko's individual feet measured by the FMA and correlated with locomotion behaviour provided enough information to reveal the mechanical and dynamic secrets of gecko locomotion. Moreover, dynamic forces were also measured by a force platform and correlated with locomotion behaviour. The difference between the forces measured by the two methods is discussed. From the results we conclude that FMA is the best way to obtain true reaction forces acting on the gecko's individual feet.

  20. Study on the measurement method of a dynamic spectrum

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Li, G.; Lin, L.; Liu, Y. L.; Li, X. X.; C-Y Lu, Stephen

    2005-01-01

    Continuous non-invasive blood component sensing and regulation is necessary for patients with metabolism disorders. Utilizing near-infrared spectroscopy for non-invasively sensing blood component concentration has been a focus topic in biomedical optics applications. It has been shown to be versatile, speedy and sensitive to several kinds of samples. However, there is no report about any successful non-invasive blood component (except the artery blood oxygen saturation) concentration detection techniques that can meet the requirements of clinic application. One of the key difficulties is the influence of individual discrepancies. Dynamic spectrum is a new non-invasive measure method for sensing blood component concentration presented recently. It can theoretically eliminate the individual discrepancies of the tissues except the pulsatile component of the artery blood. This indicates a brand new way to measure the blood component concentration and the potential to provide absolute quantitation of hemodynamic variables. In this paper, the measurement methodology to acquire the DS from photoplethysmography (PPG) is studied. A dynamic spectrometer to acquire the DS is described.

  1. Dynamic cerebral autoregulation measured with coherent hemodynamics spectroscopy (CHS)

    NASA Astrophysics Data System (ADS)

    Kainerstorfer, Jana M.; Sassaroli, Angelo; Tgavalekos, Kristen T.; Fantini, Sergio

    2015-03-01

    Coherent Hemodynamics Spectroscopy (CHS) is a novel technique for non-invasive measurements of local microcirculation quantities such as the capillary blood transit times and dynamic autoregulation. The basis of CHS is to measure, for instance with near-infrared spectroscopy (NIRS), peripheral coherent hemodynamic changes that are induced by controlled perturbations in the systemic mean arterial pressure (MAP). In this study, the MAP perturbation was induced by the fast release of two pneumatic cuffs placed around the subject's thighs after they were kept inflated (at 200 mmHg) for two minutes. The resulting transient changes in cerebral oxy- (O) and deoxy- (D) hemoglobin concentrations measured with NIRS on the prefrontal cortex are then described by a novel hemodynamic model, from which quantifiable parameters such as the capillary blood transit time and a cutoff frequency for cerebral autoregulation are obtained. We present results on eleven healthy volunteers in a protocol involving measurements during normal breathing and during hyperventilation, which is known to cause a hypocapnia-induced increase in cerebral autoregulation. The measured capillary transit time was unaffected by hyperventilation (normal breathing: 1.1±0.1 s; hyperventilation: 1.1±0.1 s), whereas the cutoff frequency of autoregulation, which increases for higher autoregulation efficiency, was indeed found to be significantly greater during hyperventilation (normal breathing: 0.017±0.002 Hz; hyperventilation: 0.034±0.005 Hz). These results provide a validation of local cerebral autoregulation measurements with the new technique of CHS.

  2. Myosin II Motors and F-Actin Dynamics Drive the Coordinated Movement of the Centrosome and Soma during CNS Glial-Guided Neuronal Migration

    SciTech Connect

    Solecki, Dr. David; Trivedi, Dr. Niraj; Govek, Eve-Ellen; Kerekes, Ryan A; Gleason, Shaun Scott; Hatten, Mary E

    2009-01-01

    Lamination of cortical regions of the vertebrate brain depends on glial-guided neuronal migration. The conserved polarity protein Par6{alpha} localizes to the centrosome and coordinates forward movement of the centrosome and soma in migrating neurons. The cytoskeletal components that produce this unique form of cell polarity and their relationship to polarity signaling cascades are unknown. We show that F-actin and Myosin II motors are enriched in the neuronal leading process and that Myosin II activity is necessary for leading process actin dynamics. Inhibition of Myosin II decreased the speed of centrosome and somal movement, whereas Myosin II activation increased coordinated movement. Ectopic expression or silencing of Par6{alpha} inhibited Myosin II motors by decreasing Myosin light-chain phosphorylation. These findings suggest leading-process Myosin II may function to 'pull' the centrosome and soma forward during glial-guided migration by a mechanism involving the conserved polarity protein Par6{alpha}.

  3. A general procedure for estimating dynamic displacements using strain measurements and operational modal analysis

    NASA Astrophysics Data System (ADS)

    Skafte, Anders; Aenlle, Manuel L.; Brincker, Rune

    2016-02-01

    Measurement systems are being installed in more and more civil structures with the purpose of monitoring the general dynamic behavior of the structure. The instrumentation is typically done with accelerometers, where experimental frequencies and mode shapes can be identified using modal analysis and used in health monitoring algorithms. But the use of accelerometers is not suitable for all structures. Structures like wind turbine blades and wings on airplanes can be exposed to lightning, which can cause the measurement systems to fail. Structures like these are often equipped with fiber sensors measuring the in-plane deformation. This paper proposes a method in which the displacement mode shapes and responses can be predicted using only strain measurements. The method relies on the newly discovered principle of local correspondence, which states that each experimental mode can be expressed as a unique subset of finite element modes. In this paper the technique is further developed to predict the mode shapes in different states of the structure. Once an estimate of the modes is found, responses can be predicted using the superposition of the modal coordinates weighted by the mode shapes. The method is validated with experimental tests on a scaled model of a two-span bridge installed with strain gauges. Random load was applied to simulate a civil structure under operating condition, and strain mode shapes were identified using operational modal analysis.

  4. Statistical prediction of dynamic distortion of inlet flow using minimum dynamic measurement. An application to the Melick statistical method and inlet flow dynamic distortion prediction without RMS measurements

    NASA Technical Reports Server (NTRS)

    Schweikhard, W. G.; Chen, Y. S.

    1986-01-01

    The Melick method of inlet flow dynamic distortion prediction by statistical means is outlined. A hypothetic vortex model is used as the basis for the mathematical formulations. The main variables are identified by matching the theoretical total pressure rms ratio with the measured total pressure rms ratio. Data comparisons, using the HiMAT inlet test data set, indicate satisfactory prediction of the dynamic peak distortion for cases with boundary layer control device vortex generators. A method for the dynamic probe selection was developed. Validity of the probe selection criteria is demonstrated by comparing the reduced-probe predictions with the 40-probe predictions. It is indicated that the the number of dynamic probes can be reduced to as few as two and still retain good accuracy.

  5. Decentralized coordination through digital technology, dynamic pricing, and Customer-Driven control: the GridWise testbed demonstration project

    SciTech Connect

    Chassin, David P.; Kiesling, Lynne

    2008-10-15

    The project highlights the idea that technology-enabled decentralized coordination can achieve the same, or better, economic and reliability benefits when compared to utility-focused centralized physical and economic control. Among the design's unique features was a retail double auction with five-minute market-clearing intervals that included residential customers as direct, active market participants. (author)

  6. Quantitative fluorescent speckle microscopy (QFSM) to measure actin dynamics.

    PubMed

    Mendoza, Michelle C; Besson, Sebastien; Danuser, Gaudenz

    2012-10-01

    Quantitative fluorescent speckle microscopy (QFSM) is a live-cell imaging method to analyze the dynamics of macromolecular assemblies with high spatial and temporal resolution. Its greatest successes were in the analysis of actin filament and adhesion dynamics in the context of cell migration and microtubule dynamics in interphase and the meiotic/mitotic spindle. Here, focus is on the former application to illustrate the procedures of FSM imaging and the computational image processing that extracts quantitative information from these experiments. QFSM is advantageous over other methods because it measures the movement and turnover kinetics of the actin filament (F-actin) network in living cells across the entire field of view. Experiments begin with the microinjection of fluorophore-labeled actin into cells, which generate a low ratio of fluorescently labeled to endogenously unlabeled actin monomers. Spinning disk confocal or wide-field imaging then visualizes fluorophore clusters (two to eight actin monomers) within the assembled F-actin network as speckles. QFSM software identifies and computationally tracks and utilizes the location, appearance, and disappearance of speckles to derive network flows and maps of the rate of filament assembly and disassembly. PMID:23042526

  7. A three-coordinate system (ecliptic, galactic, ISMF) spectral analysis of heliospheric ENA emissions using CASSINI/INCA measurements

    SciTech Connect

    Dialynas, K.; Krimigis, S. M.; Mitchell, D. G.; Roelof, E. C.; Decker, R. B

    2013-11-20

    In the present study, we use all-sky energy-resolved energetic neutral atom (ENA) maps obtained by the Ion and Neutral CAmera (INCA) instrument on board Cassini that correspond to the time period from 2003 to 2009, in four discrete energy passbands (∼5.4 to ∼55 keV), to investigate the geometrical characteristics of the belt (a broad band of emission in the sky). The heliospheric ENA emissions are mapped in three different coordinate systems (ecliptic, Galactic, and interstellar magnetic field (ISMF)), and spectral analyses are performed to further examine the belt's possible energy dependence. Our conclusions are summarized as follows: (1) the high flux ENA belt identified in the energy range of 8-42 keV is moderately well organized in Galactic coordinates, as the ENA minima appear in the vicinity of the north and south Galactic poles; (2) using minimization criteria ( B · R ∼ 0), the deviation of the ENA emissions from the equator is effectively minimized in a rotated frame, which we interpret as ISMF, where its north pole points toward 190° ecliptic longitude and 15° ecliptic latitude; (3) ENA spectra show a power-law form in energy that can be fitted with a single function presenting higher spectral slopes in the belt region and lower outside (3.4 < γ < 4.4); (4) the spectra are almost indistinguishable between the tail and the nose regions, i.e., no noticeable asymmetry is observed; (5) the consistency of the ENA distributions as a function of latitude among the different INCA channels indicates that the morphology of the belt (peak, width, and structure) is nearly energy independent from 8 keV to 30 keV (minor deviations start to appear at >35 keV); and (6) in the low count rate regions, the long-term ENA count rate profiles do not match the measured cosmic ray profiles, indicating that even the minimum ENA emissions detected by INCA are foreground ENAs.

  8. Perfusion measures from dynamic ICG scanning laser ophthalmoscopy

    NASA Astrophysics Data System (ADS)

    Larkin, Sean; Invernizzi, Alessandro; Beecher, David; Staurenghi, Giovanni; Holmes, Tim

    2010-02-01

    Movies acquired from fundus imaging using Indocyanine Green (ICG) and a scanning laser ophthalmoscope provide information for identifying vascular and other retinal abnormalities. Today, the main limitation of this modality is that it requires esoteric training for interpretation. A straightforward interpretation of these movies by objective measurements would aid in eliminating this training barrier. A software program has been developed and tested that produces and visualizes 2D maps of perfusion measures. The program corrects for frame-to-frame misalignment caused by eye motion, including rigid misalignment and warp. The alignment method uses a cross-correlation operation that automatically detects the distance due to motion between adjacent frames. The d-ICG movie is further corrected by removing flicker and vignetting artifacts. Each pixel in the corrected movie sequence is fit with a least-squares spline to yield a smooth intensity temporal profile. From the dynamics of these intensity curves, several perfusion measures are calculated. The most effective of these measures include a metric that represents the amount of time required for a vessel to fill with dye, a metric that represents the diffusion of dye, and a metric that is affected by local blood volume. These metrics are calculated from movies acquired before and after treatment for a neovascular condition. A comparison of these before and after measures may someday provide information to the clinician that helps them to evaluate disease progression and response to treatment.

  9. Understanding quantum measurement from the solution of dynamical models

    NASA Astrophysics Data System (ADS)

    Allahverdyan, Armen E.; Balian, Roger; Nieuwenhuizen, Theo M.

    2013-04-01

    The quantum measurement problem, to wit, understanding why a unique outcome is obtained in each individual experiment, is currently tackled by solving models. After an introduction we review the many dynamical models proposed over the years for elucidating quantum measurements. The approaches range from standard quantum theory, relying for instance on quantum statistical mechanics or on decoherence, to quantum-classical methods, to consistent histories and to modifications of the theory. Next, a flexible and rather realistic quantum model is introduced, describing the measurement of the z-component of a spin through interaction with a magnetic memory simulated by a Curie-Weiss magnet, including N≫1 spins weakly coupled to a phonon bath. Initially prepared in a metastable paramagnetic state, it may transit to its up or down ferromagnetic state, triggered by its coupling with the tested spin, so that its magnetization acts as a pointer. A detailed solution of the dynamical equations is worked out, exhibiting several time scales. Conditions on the parameters of the model are found, which ensure that the process satisfies all the features of ideal measurements. Various imperfections of the measurement are discussed, as well as attempts of incompatible measurements. The first steps consist in the solution of the Hamiltonian dynamics for the spin-apparatus density matrix Dˆ(t). Its off-diagonal blocks in a basis selected by the spin-pointer coupling, rapidly decay owing to the many degrees of freedom of the pointer. Recurrences are ruled out either by some randomness of that coupling, or by the interaction with the bath. On a longer time scale, the trend towards equilibrium of the magnet produces a final state Dˆ(t) that involves correlations between the system and the indications of the pointer, thus ensuring registration. Although Dˆ(t) has the form expected for ideal measurements, it only describes a large set of runs. Individual runs are approached by analyzing

  10. Inferring Small Scale Dynamics from Aircraft Measurements of Tracers

    NASA Technical Reports Server (NTRS)

    Sparling, L. C.; Einaudi, Franco (Technical Monitor)

    2000-01-01

    The millions of ER-2 and DC-8 aircraft measurements of long-lived tracers in the Upper Troposphere/Lower Stratosphere (UT/LS) hold enormous potential as a source of statistical information about subgrid scale dynamics. Extracting this information however can be extremely difficult because the measurements are made along a 1-D transect through fields that are highly anisotropic in all three dimensions. Some of the challenges and limitations posed by both the instrumentation and platform are illustrated within the context of the problem of using the data to obtain an estimate of the dissipation scale. This presentation will also include some tutorial remarks about the conditional and two-point statistics used in the analysis.

  11. Optimization of dynamic measurement of receptor kinetics by wavelet denoising.

    PubMed

    Alpert, Nathaniel M; Reilhac, Anthonin; Chio, Tat C; Selesnick, Ivan

    2006-04-01

    The most important technical limitation affecting dynamic measurements with PET is low signal-to-noise ratio (SNR). Several reports have suggested that wavelet processing of receptor kinetic data in the human brain can improve the SNR of parametric images of binding potential (BP). However, it is difficult to fully assess these reports because objective standards have not been developed to measure the tradeoff between accuracy (e.g. degradation of resolution) and precision. This paper employs a realistic simulation method that includes all major elements affecting image formation. The simulation was used to derive an ensemble of dynamic PET ligand (11C-raclopride) experiments that was subjected to wavelet processing. A method for optimizing wavelet denoising is presented and used to analyze the simulated experiments. Using optimized wavelet denoising, SNR of the four-dimensional PET data increased by about a factor of two and SNR of three-dimensional BP maps increased by about a factor of 1.5. Analysis of the difference between the processed and unprocessed means for the 4D concentration data showed that more than 80% of voxels in the ensemble mean of the wavelet processed data deviated by less than 3%. These results show that a 1.5x increase in SNR can be achieved with little degradation of resolution. This corresponds to injecting about twice the radioactivity, a maneuver that is not possible in human studies without saturating the PET camera and/or exposing the subject to more than permitted radioactivity.

  12. Beyond the blank slate: routes to learning new coordination patterns depend on the intrinsic dynamics of the learner—experimental evidence and theoretical model

    PubMed Central

    Kostrubiec, Viviane; Zanone, Pier-Giorgio; Fuchs, Armin; Kelso, J. A. Scott

    2012-01-01

    Using an approach that combines experimental studies of bimanual movements to visual stimuli and theoretical modeling, the present paper develops a dynamical account of sensorimotor learning, that is, how new skills are acquired and old ones modified. A significant aspect of our approach is the focus on the individual learner as the basic unit of analysis, in particular the quantification of predispositions and capabilities that the individual learner brings to the learning environment. Such predispositions constitute the learner's behavioral repertoire, captured here theoretically as a dynamical landscape (“intrinsic dynamics”). The learning process is demonstrated to not only lead to a relatively permanent improvement of performance in the required task—the usual outcome—but also to alter the individual's entire repertoire. Changes in the dynamical landscape due to learning are shown to result from two basic mechanisms or “routes”: bifurcation and shift. Which mechanism is selected depends the initial individual repertoire before new learning begins. Both bifurcation and shift mechanisms are accommodated by a dynamical model, a relatively straightforward development of the well-established HKB model of movement coordination. Model simulations show that although environmental or task demands may be met equally well using either mechanism, the bifurcation route results in greater stabilization of the to-be-learned behavior. Thus, stability not (or not only) error is demonstrated to be the basis of selection, both of a new pattern of behavior and the path (smooth shift versus abrupt qualitative change) that learning takes. In line with these results, recent neurophysiological evidence indicates that stability is a relevant feature around which brain activity is organized while an individual performs a coordination task. Finally, we explore the consequences of the dynamical approach to learning for theories of biological change. PMID:22876227

  13. Analysis of the effect of the parameters of the sum-difference converter of a monopulse direction-finder on the measurement precision of a target's angular coordinates

    NASA Astrophysics Data System (ADS)

    Latinskii, S. M.

    1992-11-01

    The operation of monopulse systems with converters in the form of annular waveguide bridges is analyzed. A method is proposed for analyzing the effect of the parameters of the sum-difference converters on the measurement precision of angular coordinates by means of monopulse direction-finders.

  14. Information Bounds and Optimal Analysis of Dynamic Single Molecule Measurements

    PubMed Central

    Watkins, Lucas P.; Yang, Haw

    2004-01-01

    Time-resolved single molecule fluorescence measurements may be used to probe the conformational dynamics of biological macromolecules. The best time resolution in such techniques will only be achieved by measuring the arrival times of individual photons at the detector. A general approach to the estimation of molecular parameters based on individual photon arrival times is presented. The amount of information present in a data set is quantified by the Fisher information, thereby providing a guide to deriving the basic equations relating measurement uncertainties and time resolution. Based on these information-theoretical considerations, a data analysis algorithm is presented that details the optimal analysis of single-molecule data. This method natively accounts and corrects for background photons and cross talk, and can scale to an arbitrary number of channels. By construction, and with corroboration from computer simulations, we show that this algorithm reaches the theoretical limit, extracting the maximal information out of the data. The bias inherent in the algorithm is considered and its implications for experimental design are discussed. The ideas underlying this approach are general and are expected to be applicable to any information-limited measurement. PMID:15189897

  15. Dynamic measurement of deformation using Fourier transform digital holographic interferometry

    NASA Astrophysics Data System (ADS)

    Gao, Xinya; Wu, Sijin; Yang, Lianxiang

    2013-10-01

    Digital holographic interferometry (DHI) is a well-established optical technique for measurement of nano-scale deformations. It has become more and more important due to the rapid development of applications in aerospace engineering and biomedicine. Traditionally, phase shift technique is used to quantitatively measure the deformations in DHI. However, it cannot be applied in dynamic measurement. Fourier transform phase extraction method, which can determine the phase distribution from only a single hologram, becomes a promising method to extract transient phases in DHI. This paper introduces a digital holographic interferometric system based on 2D Fourier transform phase extraction method, with which deformations of objects can be measured quickly. In the optical setup, the object beam strikes a CCD via a lens and aperture, and the reference beam is projected on the CCD through a single-mode fiber. A small inclination angle between the diverging reference beam and optical axial is introduced in order to physically separate the Fourier components in frequency domain. Phase maps are then obtained by the utilization of Fourier transform and windowed inverse Fourier transform. The capability of the Fourier transform DHI is discussed by theoretical discussion as well as experiments.

  16. Accurately measuring dynamic coefficient of friction in ultraform finishing

    NASA Astrophysics Data System (ADS)

    Briggs, Dennis; Echaves, Samantha; Pidgeon, Brendan; Travis, Nathan; Ellis, Jonathan D.

    2013-09-01

    UltraForm Finishing (UFF) is a deterministic sub-aperture computer numerically controlled grinding and polishing platform designed by OptiPro Systems. UFF is used to grind and polish a variety of optics from simple spherical to fully freeform, and numerous materials from glasses to optical ceramics. The UFF system consists of an abrasive belt around a compliant wheel that rotates and contacts the part to remove material. This work aims to accurately measure the dynamic coefficient of friction (μ), how it changes as a function of belt wear, and how this ultimately affects material removal rates. The coefficient of friction has been examined in terms of contact mechanics and Preston's equation to determine accurate material removal rates. By accurately predicting changes in μ, polishing iterations can be more accurately predicted, reducing the total number of iterations required to meet specifications. We have established an experimental apparatus that can accurately measure μ by measuring triaxial forces during translating loading conditions or while manufacturing the removal spots used to calculate material removal rates. Using this system, we will demonstrate μ measurements for UFF belts during different states of their lifecycle and assess the material removal function from spot diagrams as a function of wear. Ultimately, we will use this system for qualifying belt-wheel-material combinations to develop a spot-morphing model to better predict instantaneous material removal functions.

  17. Reinforcement learning for partially observable dynamic processes: adaptive dynamic programming using measured output data.

    PubMed

    Lewis, F L; Vamvoudakis, Kyriakos G

    2011-02-01

    Approximate dynamic programming (ADP) is a class of reinforcement learning methods that have shown their importance in a variety of applications, including feedback control of dynamical systems. ADP generally requires full information about the system internal states, which is usually not available in practical situations. In this paper, we show how to implement ADP methods using only measured input/output data from the system. Linear dynamical systems with deterministic behavior are considered herein, which are systems of great interest in the control system community. In control system theory, these types of methods are referred to as output feedback (OPFB). The stochastic equivalent of the systems dealt with in this paper is a class of partially observable Markov decision processes. We develop both policy iteration and value iteration algorithms that converge to an optimal controller that requires only OPFB. It is shown that, similar to Q -learning, the new methods have the important advantage that knowledge of the system dynamics is not needed for the implementation of these learning algorithms or for the OPFB control. Only the order of the system, as well as an upper bound on its "observability index," must be known. The learned OPFB controller is in the form of a polynomial autoregressive moving-average controller that has equivalent performance with the optimal state variable feedback gain.

  18. Neural dynamics of saccadic and smooth pursuit eye movement coordination during visual tracking of unpredictably moving targets.

    PubMed

    Grossberg, Stephen; Srihasam, Krishna; Bullock, Daniel

    2012-03-01

    How does the brain coordinate saccadic and smooth pursuit eye movements to track objects that move in unpredictable directions and speeds? Saccadic eye movements rapidly foveate peripheral visual or auditory targets, and smooth pursuit eye movements keep the fovea pointed toward an attended moving target. Analyses of tracking data in monkeys and humans reveal systematic deviations from predictions of the simplest model of saccade-pursuit interactions, which would use no interactions other than common target selection and recruitment of shared motoneurons. Instead, saccadic and smooth pursuit movements cooperate to cancel errors of gaze position and velocity, and thus to maximize target visibility through time. How are these two systems coordinated to promote visual localization and identification of moving targets? How are saccades calibrated to correctly foveate a target despite its continued motion during the saccade? The neural model proposed here answers these questions. Modeled interactions encompass motion processing areas MT, MST, FPA, DLPN and NRTP; saccade planning and execution areas FEF, LIP, and SC; the saccadic generator in the brain stem; and the cerebellum. Simulations illustrate the model's ability to functionally explain and quantitatively simulate anatomical, neurophysiological and behavioral data about coordinated saccade-pursuit tracking.

  19. Spatio-temporal co-ordination of RhoA, Rac1 and Cdc42 activation during prototypical edge protrusion and retraction dynamics

    PubMed Central

    Martin, Katrin; Reimann, Andreas; Fritz, Rafael D.; Ryu, Hyunryul; Jeon, Noo Li; Pertz, Olivier

    2016-01-01

    The three canonical Rho GTPases RhoA, Rac1 and Cdc42 co-ordinate cytoskeletal dynamics. Recent studies indicate that all three Rho GTPases are activated at the leading edge of motile fibroblasts, where their activity fluctuates at subminute time and micrometer length scales. Here, we use a microfluidic chip to acutely manipulate fibroblast edge dynamics by applying pulses of platelet-derived growth factor (PDGF) or the Rho kinase inhibitor Y-27632 (which lowers contractility). This induces acute and robust membrane protrusion and retraction events, that exhibit stereotyped cytoskeletal dynamics, allowing us to fairly compare specific morphodynamic states across experiments. Using a novel Cdc42, as well as previously described, second generation RhoA and Rac1 biosensors, we observe distinct spatio-temporal signaling programs that involve all three Rho GTPases, during protrusion/retraction edge dynamics. Our results suggest that Rac1, Cdc42 and RhoA regulate different cytoskeletal and adhesion processes to fine tune the highly plastic edge protrusion/retraction dynamics that power cell motility. PMID:26912264

  20. Dynamics and particle image velocimetry measurements of miniaturized thermoacoustic refrigerators

    NASA Astrophysics Data System (ADS)

    El-Gendy, Husam El-Deen Mohamad

    This research deals with the design and characterization of the dynamics of miniaturized thermoacoustic refrigerators (in the audible frequency range ˜ 4000 Hz) using a random array of cotton wool as the stack and a commercial piezoelectric loudspeaker as the acoustic driver. Also of primary interest is the optimization of the refrigerator by investigating the factors affecting its performance such as the stack configuration, the acoustic drive ratio, the acoustic pressure and the mean pressure in the refrigerator. Experimental measurements of cooling power, and stray heat leaks were conducted. Digital particle image velocimetry (DPIV) was used to study the acoustic flow field in the refrigerator and to correlate measurements using PIV to the characteristic acoustic measurements. A temperature difference between the refrigerator's cold and hot heat exchangers of 13°C was obtained under optimized experimental conditions. Air at atmospheric pressure was used as the working gas, and an electric power to the acoustic driver of 2 W produced 159 dB of sound, which pumped heat by the stack. Higher sound levels would raise the performance. Results showed that the cotton stack performs well at atmospheric pressure rather than higher mean pressures where nonlinear and viscous losses affect its performance. PIV measurements, such as imaged velocity fields and gas flows, showed an excellent correlation with the acoustic pressure measurements in the refrigerator. Extreme care was taken, by investigating different PIV parameters, to fulfill the conditions that distinguish between the oscillating first-order velocity field, such as the acoustic particle velocity, and the second-order nonoscillating (steady state) fields, such as acoustic streaming. Results also showed that Rayleigh streaming, produced by and superimposed on, the oscillating particle velocity, is one of the effects affecting the performance of the refrigerator, where the time it takes the streaming to be in the

  1. [Coupling coordination measurement of urbanization and eco-environment system in Huaihe River Basin of China based on fuzzy matter element theory].

    PubMed

    Guo, Yue-Ting; Xu, Jian-Gang

    2013-05-01

    Based on the statistical data of urbanization and eco-environment of 35 cities in the Huaihe River Basin of China in 2010, an index system of urbanization-eco-environment system was established by using fuzzy matter element theory, and the weight of each indicator was calculated by entropy method. The improved function of the coupling coordination degree of urbanization and eco-environment was constructed to measure this coupling coordination degree in the Huaihe River Basin. In 2010, the development level of urbanization subsystem in the Basin was lower than that of the eco-environment subsystem, and the integrated coordination index of urbanization and eco-environment was 0.186, indicating that there was a gap between the two types of indicators. The average coupling degree of urbanization and eco-environment was 0.475, indicating that the urbanization-eco-environment system was at antagonistic stage. There was a greater difference in the development level of urbanization subsystem, but a smaller difference in the development level of eco-environment subsystem among the cities. The average value of the coordination degree of all the cities was 0.706, indicating that the Huaihe River Basin was at high coordination coupling stage, and the integrated coherence and synergistic effect of urbanization and eco-environment construction in the Huaihe River Basin was higher.

  2. A Coordinated Ice-based and Airborne Snow and Ice Thickness Measurement Campaign on Arctic Sea Ice

    NASA Astrophysics Data System (ADS)

    Richter-Menge, J.; Farrell, S.; Elder, B. C.; Gardner, J. M.; Brozena, J. M.

    2011-12-01

    A rare opportunity presented itself in March 2011 when the Naval Research Laboratory (NRL) and NASA IceBridge teamed with scientists from the U.S. Army Corps of Engineers Cold Regions Research and Engineering Laboratory (CRREL) to coordinate a multi-scale approach to mapping snow depth and sea ice thickness distribution in the Arctic. Ground-truth information for calibration/validation of airborne and CryoSat-2 satellite data were collected near a manned camp deployed in support of the US Navy's Ice Expedition 2011 (ICEX 2011). The ice camp was established at a location approximately 230 km north of Prudhoe Bay, Alaska, at the edge of the perennial ice zone. The suite of measurements was strategically organized around a 9-km-long survey line that covered a wide range of ice types, including refrozen leads, deformed and undeformed first year ice, and multiyear ice. A highly concentrated set of in situ measurements of snow depth and ice thickness were taken along the survey line. Once the survey line was in place, NASA IceBridge flew a dedicated mission along the survey line, collecting data with an instrument suite that included the Airborne Topographic Mapper (ATM), a high precision, airborne scanning laser altimeter; the Digital Mapping System (DMS), nadir-viewing digital camera; and the University of Kansas ultra-wideband Frequency Modulated Continuous Wave (FMCW) snow radar. NRL also flew a dedicated mission over the survey line with complementary airborne radar, laser and photogrammetric sensors (see Brozena et al., this session). These measurements were further leveraged by a series of CryoSat-2 under flights made in the region by the instrumented NRL and NASA planes, as well as US Navy submarine underpasses of the 9-km-long survey line to collect ice draft measurements. This comprehensive suite of data provides the full spectrum of sampling resolutions from satellite, to airborne, to ground-based, to submarine and will allow for a careful determination of

  3. Diagnostic techniques for measuring suprathermal electron dynamics in plasmas (invited)

    SciTech Connect

    Coda, S.

    2008-10-15

    Plasmas, both in the laboratory and in space, are often not in thermodynamic equilibrium, and the plasma electron distribution function is accordingly non-Maxwellian. Suprathermal electron tails can be generated by external drives, such as rf waves and electric fields, or internal ones, such as instabilities and magnetic reconnection. The variety and importance of the phenomena in which suprathermal electrons play a significant role explains an enduring interest in diagnostic techniques to investigate their properties and dynamics. X-ray bremsstrahlung emission has been studied in hot magnetized plasmas for well over two decades, flanked progressively by electron-cyclotron emission in geometries favoring the high-energy end of the distribution function (high-field-side, vertical, oblique emission), by electron-cyclotron absorption, by spectroscopic techniques, and at lower temperatures, by Langmuir probes and electrostatic analyzers. Continuous progress in detector technology and in measurement and analysis techniques, increasingly sophisticated layouts (multichannel and tomographic systems, imaging geometries), and highly controlled suprathermal generation methods (e.g., perturbative rf modulation) have all been brought to bear in recent years on an increasingly detailed, although far from complete, understanding of suprathermal electron dynamics.

  4. Measurement of dynamic surface tension by mechanically vibrated sessile droplets

    NASA Astrophysics Data System (ADS)

    Iwata, Shuichi; Yamauchi, Satoko; Yoshitake, Yumiko; Nagumo, Ryo; Mori, Hideki; Kajiya, Tadashi

    2016-04-01

    We developed a novel method for measuring the dynamic surface tension of liquids using mechanically vibrated sessile droplets. Under continuous mechanical vibration, the shape of the deformed droplet was fitted by numerical analysis, taking into account the force balance at the drop surface and the momentum equation. The surface tension was determined by optimizing four parameters: the surface tension, the droplet's height, the radius of the droplet-substrate contact area, and the horizontal symmetrical position of the droplet. The accuracy and repeatability of the proposed method were confirmed using drops of distilled water as well as viscous aqueous glycerol solutions. The vibration frequency had no influence on surface tension in the case of pure liquids. However, for water-soluble surfactant solutions, the dynamic surface tension gradually increased with vibration frequency, which was particularly notable for low surfactant concentrations slightly below the critical micelle concentration. This frequency dependence resulted from the competition of two mechanisms at the drop surface: local surface deformation and surfactant transport towards the newly generated surface.

  5. Methodological aspects of EEG and body dynamics measurements during motion

    PubMed Central

    Reis, Pedro M. R.; Hebenstreit, Felix; Gabsteiger, Florian; von Tscharner, Vinzenz; Lochmann, Matthias

    2014-01-01

    EEG involves the recording, analysis, and interpretation of voltages recorded on the human scalp which originate from brain gray matter. EEG is one of the most popular methods of studying and understanding the processes that underlie behavior. This is so, because EEG is relatively cheap, easy to wear, light weight and has high temporal resolution. In terms of behavior, this encompasses actions, such as movements that are performed in response to the environment. However, there are methodological difficulties which can occur when recording EEG during movement such as movement artifacts. Thus, most studies about the human brain have examined activations during static conditions. This article attempts to compile and describe relevant methodological solutions that emerged in order to measure body and brain dynamics during motion. These descriptions cover suggestions on how to avoid and reduce motion artifacts, hardware, software and techniques for synchronously recording EEG, EMG, kinematics, kinetics, and eye movements during motion. Additionally, we present various recording systems, EEG electrodes, caps and methods for determinating real/custom electrode positions. In the end we will conclude that it is possible to record and analyze synchronized brain and body dynamics related to movement or exercise tasks. PMID:24715858

  6. Measurement of dynamic surface tension by mechanically vibrated sessile droplets.

    PubMed

    Iwata, Shuichi; Yamauchi, Satoko; Yoshitake, Yumiko; Nagumo, Ryo; Mori, Hideki; Kajiya, Tadashi

    2016-04-01

    We developed a novel method for measuring the dynamic surface tension of liquids using mechanically vibrated sessile droplets. Under continuous mechanical vibration, the shape of the deformed droplet was fitted by numerical analysis, taking into account the force balance at the drop surface and the momentum equation. The surface tension was determined by optimizing four parameters: the surface tension, the droplet's height, the radius of the droplet-substrate contact area, and the horizontal symmetrical position of the droplet. The accuracy and repeatability of the proposed method were confirmed using drops of distilled water as well as viscous aqueous glycerol solutions. The vibration frequency had no influence on surface tension in the case of pure liquids. However, for water-soluble surfactant solutions, the dynamic surface tension gradually increased with vibration frequency, which was particularly notable for low surfactant concentrations slightly below the critical micelle concentration. This frequency dependence resulted from the competition of two mechanisms at the drop surface: local surface deformation and surfactant transport towards the newly generated surface.

  7. Microsensor measurements of hydrogen gas dynamics in cyanobacterial microbial mats.

    PubMed

    Nielsen, Michael; Revsbech, Niels P; Kühl, Michael

    2015-01-01

    We used a novel amperometric microsensor for measuring hydrogen gas production and consumption at high spatio-temporal resolution in cyanobacterial biofilms and mats dominated by non-heterocystous filamentous cyanobacteria (Microcoleus chtonoplastes and Oscillatoria sp.). The new microsensor is based on the use of an organic electrolyte and a stable internal reference system and can be equipped with a chemical sulfide trap in the measuring tip; it exhibits very stable and sulfide-insensitive measuring signals and a high sensitivity (1.5-5 pA per μmol L(-1) H2). Hydrogen gas measurements were done in combination with microsensor measurements of scalar irradiance, O2, pH, and H2S and showed a pronounced H2 accumulation (of up to 8-10% H2 saturation) within the upper mm of cyanobacterial mats after onset of darkness and O2 depletion. The peak concentration of H2 increased with the irradiance level prior to darkening. After an initial build-up over the first 1-2 h in darkness, H2 was depleted over several hours due to efflux to the overlaying water, and due to biogeochemical processes in the uppermost oxic layers and the anoxic layers of the mats. Depletion could be prevented by addition of molybdate pointing to sulfate reduction as a major sink for H2. Immediately after onset of illumination, a short burst of presumably photo-produced H2 due to direct biophotolysis was observed in the illuminated but anoxic mat layers. As soon as O2 from photosynthesis started to accumulate, the H2 was consumed rapidly and production ceased. Our data give detailed insights into the microscale distribution and dynamics of H2 in cyanobacterial biofilms and mats, and further support that cyanobacterial H2 production can play a significant role in fueling anaerobic processes like e.g., sulfate reduction or anoxygenic photosynthesis in microbial mats.

  8. Microsensor measurements of hydrogen gas dynamics in cyanobacterial microbial mats

    PubMed Central

    Nielsen, Michael; Revsbech, Niels P.; Kühl, Michael

    2015-01-01

    We used a novel amperometric microsensor for measuring hydrogen gas production and consumption at high spatio-temporal resolution in cyanobacterial biofilms and mats dominated by non-heterocystous filamentous cyanobacteria (Microcoleus chtonoplastes and Oscillatoria sp.). The new microsensor is based on the use of an organic electrolyte and a stable internal reference system and can be equipped with a chemical sulfide trap in the measuring tip; it exhibits very stable and sulfide-insensitive measuring signals and a high sensitivity (1.5–5 pA per μmol L-1 H2). Hydrogen gas measurements were done in combination with microsensor measurements of scalar irradiance, O2, pH, and H2S and showed a pronounced H2 accumulation (of up to 8–10% H2 saturation) within the upper mm of cyanobacterial mats after onset of darkness and O2 depletion. The peak concentration of H2 increased with the irradiance level prior to darkening. After an initial build-up over the first 1–2 h in darkness, H2 was depleted over several hours due to efflux to the overlaying water, and due to biogeochemical processes in the uppermost oxic layers and the anoxic layers of the mats. Depletion could be prevented by addition of molybdate pointing to sulfate reduction as a major sink for H2. Immediately after onset of illumination, a short burst of presumably photo-produced H2 due to direct biophotolysis was observed in the illuminated but anoxic mat layers. As soon as O2 from photosynthesis started to accumulate, the H2 was consumed rapidly and production ceased. Our data give detailed insights into the microscale distribution and dynamics of H2 in cyanobacterial biofilms and mats, and further support that cyanobacterial H2 production can play a significant role in fueling anaerobic processes like e.g., sulfate reduction or anoxygenic photosynthesis in microbial mats. PMID:26257714

  9. Local measurements of plasma ion dynamics with optical probes

    SciTech Connect

    Kuritsyn, Alexey; Craig, Darren; Fiksel, Gennady; Miller, Matt; Cylinder, David; Yamada, Masaaki

    2006-10-15

    Two insertable optical probes have been constructed to measure local ion temperature and flow velocity using the idea proposed by Fiksel et al. [Rev. Sci. Instrum. 69, 2024 (1998)]. The light from plasma is collected by an optical fiber bundle and transported to a high resolution spectrometer. Spatial resolution of a few centimeters is achieved by using a collimator and a view dump. One ion dynamics spectroscopy (IDS) probe is employed in the edge plasma of Madison Symmetric Torus reversed field pinch in combination with the high throughput (f/4.5) and high resolution (0.15 nm/mm) IDS-II spectrometer. It has provided local ion temperature measurements of carbon and helium impurities with temporal resolution of 10 {mu}s and accuracy of about 5 eV. The second instrument is used on the Magnetic Reconnection eXperiment, where the local temperature of helium ions ({approx}10 eV) has been measured with 1 eV accuracy. Details of the designs, calibrations, and data analysis are described.

  10. Characterizing Suspension Plasma Spray Coating Formation Dynamics through Curvature Measurements

    NASA Astrophysics Data System (ADS)

    Chidambaram Seshadri, Ramachandran; Dwivedi, Gopal; Viswanathan, Vaishak; Sampath, Sanjay

    2016-10-01

    Suspension plasma spraying (SPS) enables the production of variety of microstructures with unique mechanical and thermal properties. In SPS, a liquid carrier (ethanol/water) is used to transport the sub-micrometric feedstock into the plasma jet. Considering complex deposition dynamics of SPS technique, there is a need to better understand the relationships among spray conditions, ensuing particle behavior, deposition stress evolution and resultant properties. In this study, submicron yttria-stabilized zirconia particles suspended in ethanol were sprayed using a cascaded arc plasma torch. The stresses generated during the deposition of the layers (termed evolving stress) were monitored via the change in curvature of the substrate measured using an in situ measurement apparatus. Depending on the deposition conditions, coating microstructures ranged from feathery porous to dense/cracked deposits. The evolving stresses and modulus were correlated with the observed microstructures and visualized via process maps. Post-deposition bi-layer curvature measurement via low temperature thermal cycling was carried out to quantify the thermo-elastic response of different coatings. Lastly, preliminary data on furnace cycle durability of different coating microstructures were evaluated. This integrated study involving in situ diagnostics and ex situ characterization along with process maps provides a framework to describe coating formation mechanisms, process parametrics and microstructure description.

  11. Measurement of an atomic quadrupole moment using dynamic decoupling

    NASA Astrophysics Data System (ADS)

    Akerman, Nitzan; Shaniv, Ravid; Ozeri, Roee

    2016-05-01

    Some of the best clocks today are ion-based optical clocks. These clocks are referenced to a narrow optical transition in a trapped ion. An example for such a narrow transition is the electric quadrupole E 2 transition between states with identical parity. An important systematic shift of such a transition is the quadrupole shift resulting from the electric field gradient inherent to the ion trap. We present a new dynamic decoupling method that rejects magnetic field noise while measuring the small quadrupole shift of the optical clock transition. Using our sequence we measured the quadrupole moment of the 4D5/2 level in a trapped 88 Sr+ ion to be 2 .973-0 . 033 + 0 . 026 ea02 , where e is the electron charge and a0 is the Bohr radius. Our measurement improves the uncertainty of this value by an order of magnitude and thus helps mitigate an important systematic uncertainty in 88 Sr+ based optical atomic clocks and verifies complicated many-body quantum calculations.

  12. Thermographic measurement of thermal bridges in buildings under dynamic behavior

    NASA Astrophysics Data System (ADS)

    Ferrarini, G.; Bison, P.; Bortolin, A.; Cadelano, G.; De Carli, M.

    2016-05-01

    The accurate knowledge of the thermal performance could reduce significantly the impact of buildings on global energy consumption. Infrared thermography is widely recognized as one of the key technologies for building surveys, thanks to its ability to acquire at a glance thermal images of the building envelope. However, a spot measurement could be misleading when the building is under dynamic thermal conditions. In this case data should be acquired for hours or days, depending on the thermal properties of the walls. Long term thermographic monitoring are possible but imply strong challenges from a practical standpoint. This work investigates the possibilities and limitations of spot thermographic surveys coupled with contact probes, that are able to acquire continuously the thermal signal for days, to investigate the thermal bridges of a building. The goal is the estimation of the reliability and accuracy of the measurement under realistic environmental conditions. Firstly, numerical simulations are performed to determine the reference value of an experimental case. Then a long term thermographic survey is performed and integrated with the contact probe measurement, assessing the feasibility of the method.

  13. Measurements of Dynamical Dipole in isospin asymmetric fusion reactions

    NASA Astrophysics Data System (ADS)

    Giaz, A.; Corsi, A.; Camera, F.; Bracco, A.; Crespi, F. C. L.; Leoni, S.; Nicolini, R.; Vandone, V.; Benzoni, G.; Blasi, N.; Brambilla, S.; Million, B.; Wieland, O.; Cinausero, M.; Degelier, M.; Gramegna, F.; Kravchuk, V. L.; Marchi, T.; Rizzi, V.; Bardelli, L.; Barlini, S.; Bini, M.; Carboni, S.; Casini, G.; Chiari, M.; Nannini, A.; Pasquali, G.; Piantelli, S.; Poggi, G.; Baiocco, G.; Bruno, M.; D'agostino, M.; Morelli, L.; Vannini, V.; Colonna, M.; Di Toro, M.; Rizzo, C.; Bednarcyk, P.; Ciemala, M.; Kmiecik, M.; Maj, A.; Mazurek, K.; Menczynski, W.; Alba, R.; Maiolino, C.; Santonocito, D.; Montanari, D.; Ordine, A.

    2012-05-01

    In heavy ion nuclear reactions the process leading to complete fusion is expected to produce pre-equilibrium γ-ray emission, if particular conditions are met. Indeed, when there is an N/Z asymmetry between projectile and target, charge equilibration takes place with a collective dipole oscillation, called Dynamical Dipole (DD), associated to a γ-ray emission. The existing experimental data concerning this pre-equilibrium γ-ray emission are still rather scarce and manly concentrated in the A≊132 mass region. The very preliminary results concerning the measurement of the DD γ-ray emission in the fusion reaction 16O (Elab=192 MeV) + 116Sn at 12 MeV/u will be presented and compared with the γ yield measured for the same reaction at 8.1 and 15.6 MeV/u. The present experiment aims at the measurement of the total emission yield of the DD at 12 MeV/u where the predicted theoretical yield does not completely reproduce the experimental data. The experiment has been performed at the INFN Legnaro Laboratories using the GARFIELD-HECTOR array.

  14. The measurement of specific dynamic action in fishes.

    PubMed

    Chabot, D; Koenker, R; Farrell, A P

    2016-01-01

    Specific dynamic action (SDA) is the postprandial increase in oxygen uptake. Whereas it is easy to measure in fishes that remain calm and motionless during the entire digestion period, spontaneous locomotor activity is a frequent problem that leads to overestimation of SDA amplitude and magnitude (area under the curve, bound by the standard metabolic rate, SMR). Few studies have attempted to remove the effect of fish activity on SDA. A new method, non-parametric quantile regression, is described to estimate SDA even when pronounced circadian activity cycles are present. Data from juvenile Atlantic cod Gadus morhua are used to demonstrate its use and advantages compared with traditional techniques. Software (scripts in the R language) is provided to facilitate its use. PMID:26768974

  15. Intra-arterial pressure measurement in neonates: dynamic response requirements.

    PubMed

    van Genderingen, H R; Gevers, M; Hack, W W

    1995-02-01

    A computer simulation of a catheter manometer system was used to quantify measurement errors in neonatal blood pressure parameters. Accurate intra-arterial pressure recordings of 21 critically ill newborns were fed into this simulated system. The dynamic characteristics, natural frequency and damping coefficient, were varied from 2.5 to 60 Hz and from 0.1 to 1.4, respectively. As a result, errors in systolic, diastolic and pulse arterial pressure were obtained as a function of natural frequency and damping coefficient. Iso-error curves for 2%, 5% and 10% were constructed. Using these curves, the maximum inaccuracy of any neonatal catheter manometer system can be determined and used in the clinical setting.

  16. Picosecond X-ray streak camera dynamic range measurement

    NASA Astrophysics Data System (ADS)

    Zuber, C.; Bazzoli, S.; Brunel, P.; Fronty, J.-P.; Gontier, D.; Goulmy, C.; Raimbourg, J.; Rubbelynck, C.; Trosseille, C.

    2016-09-01

    Streak cameras are widely used to record the spatio-temporal evolution of laser-induced plasma. A prototype of picosecond X-ray streak camera has been developed and tested by Commissariat à l'Énergie Atomique et aux Énergies Alternatives to answer the Laser MegaJoule specific needs. The dynamic range of this instrument is measured with picosecond X-ray pulses generated by the interaction of a laser beam and a copper target. The required value of 100 is reached only in the configurations combining the slowest sweeping speed and optimization of the streak tube electron throughput by an appropriate choice of high voltages applied to its electrodes.

  17. Structural anomaly and dynamic heterogeneity in cycloether/water binary mixtures: Signatures from composition dependent dynamic fluorescence measurements and computer simulations

    NASA Astrophysics Data System (ADS)

    Indra, Sandipa; Guchhait, Biswajit; Biswas, Ranjit

    2016-03-01

    We have performed steady state UV-visible absorption and time-resolved fluorescence measurements and computer simulations to explore the cosolvent mole fraction induced changes in structural and dynamical properties of water/dioxane (Diox) and water/tetrahydrofuran (THF) binary mixtures. Diox is a quadrupolar solvent whereas THF is a dipolar one although both are cyclic molecules and represent cycloethers. The focus here is on whether these cycloethers can induce stiffening and transition of water H-bond network structure and, if they do, whether such structural modification differentiates the chemical nature (dipolar or quadrupolar) of the cosolvent molecules. Composition dependent measured fluorescence lifetimes and rotation times of a dissolved dipolar solute (Coumarin 153, C153) suggest cycloether mole-fraction (XTHF/Diox) induced structural transition for both of these aqueous binary mixtures in the 0.1 ≤ XTHF/Diox ≤ 0.2 regime with no specific dependence on the chemical nature. Interestingly, absorption measurements reveal stiffening of water H-bond structure in the presence of both the cycloethers at a nearly equal mole-fraction, XTHF/Diox ˜ 0.05. Measurements near the critical solution temperature or concentration indicate no role for the solution criticality on the anomalous structural changes. Evidences for cycloether aggregation at very dilute concentrations have been found. Simulated radial distribution functions reflect abrupt changes in respective peak heights at those mixture compositions around which fluorescence measurements revealed structural transition. Simulated water coordination numbers (for a dissolved C153) and number of H-bonds also exhibit minima around these cosolvent concentrations. In addition, several dynamic heterogeneity parameters have been simulated for both the mixtures to explore the effects of structural transition and chemical nature of cosolvent on heterogeneous dynamics of these systems. Simulated four-point dynamic

  18. Structural anomaly and dynamic heterogeneity in cycloether/water binary mixtures: Signatures from composition dependent dynamic fluorescence measurements and computer simulations.

    PubMed

    Indra, Sandipa; Guchhait, Biswajit; Biswas, Ranjit

    2016-03-28

    We have performed steady state UV-visible absorption and time-resolved fluorescence measurements and computer simulations to explore the cosolvent mole fraction induced changes in structural and dynamical properties of water/dioxane (Diox) and water/tetrahydrofuran (THF) binary mixtures. Diox is a quadrupolar solvent whereas THF is a dipolar one although both are cyclic molecules and represent cycloethers. The focus here is on whether these cycloethers can induce stiffening and transition of water H-bond network structure and, if they do, whether such structural modification differentiates the chemical nature (dipolar or quadrupolar) of the cosolvent molecules. Composition dependent measured fluorescence lifetimes and rotation times of a dissolved dipolar solute (Coumarin 153, C153) suggest cycloether mole-fraction (X(THF)/Diox) induced structural transition for both of these aqueous binary mixtures in the 0.1 ≤ X(THF)/Diox ≤ 0.2 regime with no specific dependence on the chemical nature. Interestingly, absorption measurements reveal stiffening of water H-bond structure in the presence of both the cycloethers at a nearly equal mole-fraction, X(THF)/Diox ∼ 0.05. Measurements near the critical solution temperature or concentration indicate no role for the solution criticality on the anomalous structural changes. Evidences for cycloether aggregation at very dilute concentrations have been found. Simulated radial distribution functions reflect abrupt changes in respective peak heights at those mixture compositions around which fluorescence measurements revealed structural transition. Simulated water coordination numbers (for a dissolved C153) and number of H-bonds also exhibit minima around these cosolvent concentrations. In addition, several dynamic heterogeneity parameters have been simulated for both the mixtures to explore the effects of structural transition and chemical nature of cosolvent on heterogeneous dynamics of these systems. Simulated four

  19. Z-correction, a method for achieving ultraprecise self-calibration on large area coordinate measurement machines for photomasks

    NASA Astrophysics Data System (ADS)

    Ekberg, Peter; Stiblert, Lars; Mattsson, Lars

    2014-05-01

    High-quality photomasks are a prerequisite for the production of flat panel TVs, tablets and other kinds of high-resolution displays. During the past years, the resolution demand has become more and more accelerated, and today, the high-definition standard HD, 1920 × 1080 pixels2, is well established, and already the next-generation so-called ultra-high-definition UHD or 4K display is entering the market. Highly advanced mask writers are used to produce the photomasks needed for the production of such displays. The dimensional tolerance in X and Y on absolute pattern placement on these photomasks, with sizes of square meters, has been in the range of 200-300 nm (3σ), but is now on the way to be <150 nm (3σ). To verify these photomasks, 2D ultra-precision coordinate measurement machines are used with even tighter tolerance requirements. The metrology tool MMS15000 is today the world standard tool used for the verification of large area photomasks. This paper will present a method called Z-correction that has been developed for the purpose of improving the absolute X, Y placement accuracy of features on the photomask in the writing process. However, Z-correction is also a prerequisite for achieving X and Y uncertainty levels <90 nm (3σ) in the self-calibration process of the MMS15000 stage area of 1.4 × 1.5 m2. When talking of uncertainty specifications below 200 nm (3σ) of such a large area, the calibration object used, here an 8-16 mm thick quartz plate of size approximately a square meter, cannot be treated as a rigid body. The reason for this is that the absolute shape of the plate will be affected by gravity and will therefore not be the same at different places on the measurement machine stage when it is used in the self-calibration process. This mechanical deformation will stretch or compress the top surface (i.e. the image side) of the plate where the pattern resides, and therefore spatially deform the mask pattern in the X- and Y-directions. Errors due

  20. Modelling coordination in hospital emergency departments through social network analysis.

    PubMed

    Hossain, Liaquat; Kit Guan, Danny Chun

    2012-04-01

    Coordination theory provides a theoretical framework for analysing complex processes of project groups working towards a common goal. In this study, we explore the relationship between coordination and social networks for the development of a network-based coordination model. This model is applied to measure the performance and quality of complex and dynamic project coordination such as in hospital emergency departments. The dataset used for the study was collected by the 2004 National Hospital Ambulatory Medical Care Survey--a national probability sample survey of visits to emergency and outpatient departments of non-Federal, short-stay and general hospitals in the United States. Using social network analysis, this study allows us to understand the possible causes of inefficient coordination performance and coordination quality resulting in access blocks.

  1. Experimental measurement of utricle system dynamic response to inertial stimulus.

    PubMed

    Dunlap, M D; Grant, J W

    2014-08-01

    The membranous utricle sac of the red-eared turtle was mounted in a piezoelectric actuated platform mounted on the stage of a light microscope. The piezoelectric actuator oscillated the base of the neuroepithelium along a linear axis. Displacements were in the plane of the utricle and consisted of a linear sinusoidal-sweep signal starting at 0 and increasing to 500 Hz over 5 s. This inertial stimulus caused measurable shear displacement of the otoconial layer's dorsal surface, resulting in shear deformation of the gelatinous and column filament layers. Displacements of the otoconial layer and a reference point on the neuroepithelium were filmed at 2,000 frames/s with a high-speed video camera during oscillations. Image registration was performed on the video to track displacements with a resolution better than 15 nm. The displacement waveforms were then matched to a linear second-order model of the dynamic system. The model match identified two system mechanical parameters-the natural circular frequency ω n and the damping ratio ζ-that characterized the utricle dynamic response. The median values found for the medial-lateral axis on 20 utricles with 95 % confidence intervals in parenthesis were as follows: ω n = 374 (353, 396) Hz and ζ = 0.50 (0.47, 0.53). The anterior-posterior axis values were not significantly different: ω n = 409 (390, 430) Hz and ζ = 0.53 (0.48, 0.57). The results have two relevant and significant dynamic system findings: (1) a higher than expected natural frequency and (2) significant under damping. Previous to this study, utricular systems were treated as overdamped and with natural frequencies much lower that measured here. Both of these system performance findings result in excellent utricle time response to acceleration stimuli and a broad frequency bandwidth up to 100 Hz. This study is the first to establish the upper end of this mechanical system frequency response of the utricle in any animal.

  2. Clinical measures associated with dynamic balance and functional movement.

    PubMed

    Teyhen, Deydre S; Shaffer, Scott W; Lorenson, Chelsea L; Greenberg, Moshe D; Rogers, Shay M; Koreerat, Christina M; Villena, Sarah L; Zosel, Kristen L; Walker, Michael J; Childs, John C

    2014-05-01

    Decreased balance and impaired functional movement have been linked with increased injury risk. The purpose of our study was to determine the association between specific measures of power, strength, flexibility, balance, and endurance compared with more global measures of dynamic balance, using the Y-Balance Test (YBT), and functional movement, using the functional movement screen (FMS), in healthy soldiers. Our participants (n = 64; 53 men, 11 women) were healthy active duty service members (25.2 ± 3.8 years, 25.1 ± 3.1 kg·m(-2)). Seventeen tests with 38 associated measures of strength, power, flexibility, endurance, balance, and functional measures were assessed. A significant Pearson product moment correlation (r > 0.2 and p < 0.01) was used to narrow the number of variables of interest. Two hierarchical stepwise regression analyses were performed to determine the most parsimonious set of variables associated with the YBT and FMS performance scores. Our results included a 4 variable model (F = 13.4, p < 0.001) that was associated with YBT scores (R = 0.72, R2 = 0.51). Superior performance on the YBT was associated with better performance on the FMS lunge and upper trunk mobility tests, decreased number of hops during a 6-m hop test, and greater gastrocnemius flexibility. A second 4 variable model (F = 11.813, p < 0.001) was associated with FMS scores (R = 0.70, R2 = 0.50). Superior performance on the FMS was associated with greater anterior reach on the YBT, greater distance on the crossover hop test, increased hamstring flexibility, and higher levels of self-reported function through the lower-extremity functional scale. Physical fitness leaders and clinicians could use these models to inform decision making when developing and assessing the outcomes of a personalized intervention program for those with low FMS and YBT scores. PMID:24755867

  3. Clinical measures associated with dynamic balance and functional movement.

    PubMed

    Teyhen, Deydre S; Shaffer, Scott W; Lorenson, Chelsea L; Greenberg, Moshe D; Rogers, Shay M; Koreerat, Christina M; Villena, Sarah L; Zosel, Kristen L; Walker, Michael J; Childs, John C

    2014-05-01

    Decreased balance and impaired functional movement have been linked with increased injury risk. The purpose of our study was to determine the association between specific measures of power, strength, flexibility, balance, and endurance compared with more global measures of dynamic balance, using the Y-Balance Test (YBT), and functional movement, using the functional movement screen (FMS), in healthy soldiers. Our participants (n = 64; 53 men, 11 women) were healthy active duty service members (25.2 ± 3.8 years, 25.1 ± 3.1 kg·m(-2)). Seventeen tests with 38 associated measures of strength, power, flexibility, endurance, balance, and functional measures were assessed. A significant Pearson product moment correlation (r > 0.2 and p < 0.01) was used to narrow the number of variables of interest. Two hierarchical stepwise regression analyses were performed to determine the most parsimonious set of variables associated with the YBT and FMS performance scores. Our results included a 4 variable model (F = 13.4, p < 0.001) that was associated with YBT scores (R = 0.72, R2 = 0.51). Superior performance on the YBT was associated with better performance on the FMS lunge and upper trunk mobility tests, decreased number of hops during a 6-m hop test, and greater gastrocnemius flexibility. A second 4 variable model (F = 11.813, p < 0.001) was associated with FMS scores (R = 0.70, R2 = 0.50). Superior performance on the FMS was associated with greater anterior reach on the YBT, greater distance on the crossover hop test, increased hamstring flexibility, and higher levels of self-reported function through the lower-extremity functional scale. Physical fitness leaders and clinicians could use these models to inform decision making when developing and assessing the outcomes of a personalized intervention program for those with low FMS and YBT scores.

  4. Dynamic measurements and uncertainty estimation of clinical thermometers using Monte Carlo method

    NASA Astrophysics Data System (ADS)

    Ogorevc, Jaka; Bojkovski, Jovan; Pušnik, Igor; Drnovšek, Janko

    2016-09-01

    Clinical thermometers in intensive care units are used for the continuous measurement of body temperature. This study describes a procedure for dynamic measurement uncertainty evaluation in order to examine the requirements for clinical thermometer dynamic properties in standards and recommendations. In this study thermistors were used as temperature sensors, transient temperature measurements were performed in water and air and the measurement data were processed for the investigation of thermometer dynamic properties. The thermometers were mathematically modelled. A Monte Carlo method was implemented for dynamic measurement uncertainty evaluation. The measurement uncertainty was analysed for static and dynamic conditions. Results showed that dynamic uncertainty is much larger than steady-state uncertainty. The results of dynamic uncertainty analysis were applied on an example of clinical measurements and were compared to current requirements in ISO standard for clinical thermometers. It can be concluded that there was no need for dynamic evaluation of clinical thermometers for continuous measurement, while dynamic measurement uncertainty was within the demands of target uncertainty. Whereas in the case of intermittent predictive thermometers, the thermometer dynamic properties had a significant impact on the measurement result. Estimation of dynamic uncertainty is crucial for the assurance of traceable and comparable measurements.

  5. Thermospheric neutral wind signatures dependent on the east-west component of the interplanetary magnetic field for Northern and Southern Hemispheres as measured from Dynamics Explorer-2

    NASA Technical Reports Server (NTRS)

    Thayer, J. P.; Killeen, T. L.; Mccormac, F. G.; Tschan, C. R.; Ponthieu, J.-J.; Spencer, N. W.

    1987-01-01

    DE-2 neutral-wind measurements obtained between November and January 1981-1982 and 1982-1983 were analyzed to investigate the effect of the sign of the IMF By component on neutral thermosphere dynamics at F-region altitudes. Maps of the mean neutral circulation for the northern (winter) and southern (summer) polar regions were derived for By positive and negative using polar geomagnetic coordinates. The mean neutral winds demonstrate clear By-dependent neutral wind signatures in both hemispheres.

  6. Measurements of particle dynamics in slow, dense granular Couette flow

    NASA Astrophysics Data System (ADS)

    Mueth, Daniel M.

    Experimental measurements of particle dynamics on the lower surface of a 3D Couette cell containing monodisperse spheres are reported. The average radial density and velocity profiles are similar to those previously measured within the bulk and on the lower surface of the 3D cell filled with mustard seeds. Observations of the evolution of particle velocities over time reveal distinct motion events, intervals where previously stationary particles move for a short duration before jamming again. The cross-correlation between the velocities of two particles at a given distance r from the moving wall reveals a characteristic lengthscale over which the particles are correlated. The autocorrelation of a single particle's velocity reveals a characteristic timescale tau which decreases with distance from the inner moving wall. This may be attributed to the increasing rarity at which the discrete motion events occur and the reduced duration of those events at large r. The radial profile of the velocity fluctuations about their mean, deltavtheta(r), was found to be almost identical in shape to the Gaussian component of the velocity profile vtheta(r). The relationship between the RMS azimuthal velocity fluctuations, delta vtheta(r), and average shear rate, ġ (r), was found to be deltav theta ∝ ġ alpha with alpha = 0.52 +/- 0.04. These observations are compared with other recent experiments and with the modified hydrodynamic model recently introduced by Bocquet et al.

  7. Measurements of particle dynamics in slow, dense granular Couette flow

    NASA Astrophysics Data System (ADS)

    Mueth, Daniel M.

    2003-01-01

    Experimental measurements of particle dynamics on the lower surface of a three-dimensional (3D) Couette cell containing monodisperse spheres are reported. The average radial density and velocity profiles are similar to those previously measured within the bulk and on the lower surface of the 3D cell filled with mustard seeds. Observations of the evolution of particle velocities over time reveal distinct motion events, intervals where previously stationary particles move for a short duration before jamming again. The cross correlation between the velocities of two particles at a given distance r from the moving wall reveals a characteristic length scale over which the particles are correlated. The autocorrelation of a single particle’s velocity reveals a characteristic time scale τ, which decreases with increasing distance from the inner moving wall. This may be attributed to the increasing rarity at which the discrete motion events occur and the reduced duration of those events at large r. The relationship between the rms azimuthal velocity fluctuations, δvθ(r), and average shear rate, γ˙(r), was found to be δvθ∝γ˙α with α=0.52±0.04. These observations are compared with other recent experiments and with the modified hydrodynamic model recently introduced by Bocquet et al.

  8. Dynamical Mass Measurements of Contaminated Galaxy Clusters Using Machine Learning

    NASA Astrophysics Data System (ADS)

    Ntampaka, Michelle; Trac, Hy; Sutherland, Dougal; Fromenteau, Sebastien; Poczos, Barnabas; Schneider, Jeff

    2016-01-01

    Galaxy clusters are a rich source of information for examining fundamental astrophysical processes and cosmological parameters, however, employing clusters as cosmological probes requires accurate mass measurements derived from cluster observables. We study dynamical mass measurements of galaxy clusters contaminated by interlopers, and show that a modern machine learning (ML) algorithm can predict masses by better than a factor of two compared to a standard scaling relation approach. We create a mock catalog from Multidark's publicly-available N-body MDPL1 simulation where a simple cylindrical cut around the cluster center allows interlopers to contaminate the clusters. In the standard approach, we use a power law scaling relation to infer cluster mass from galaxy line of sight (LOS) velocity dispersion. The presence of interlopers in the catalog produces a wide, flat fractional mass error distribution, with width = 2.13. We employ the Support Distribution Machine (SDM) class of algorithms to learn from distributions of data to predict single values. Applied to distributions of galaxy observables such as LOS velocity and projected distance from the cluster center, SDM yields better than a factor-of-two improvement (width = 0.67). Remarkably, SDM applied to contaminated clusters is better able to recover masses than even a scaling relation approach applied to uncontaminated clusters. We show that the SDM method more accurately reproduces the cluster mass function, making it a valuable tool for employing cluster observations to evaluate cosmological models.

  9. Measurement realities of current collection in dynamic space plasma environments

    NASA Technical Reports Server (NTRS)

    Szuszczewicz, Edward P.

    1990-01-01

    Theories which describe currents collected by conducting and non-conducting bodies immersed in plasmas have many of their concepts based upon the fundamentals of sheath-potential distributions and charged-particle behavior in superimposed electric and magnetic fields. Those current-collecting bodies (or electrodes) may be Langmuir probes, electric field detectors, aperture plates on ion mass spectrometers and retarding potential analyzers, or spacecraft and their rigid and tethered appendages. Often the models are incomplete in representing the conditions under which the current-voltage characteristics of the electrode and its system are to be measured. In such cases, the experimenter must carefully take into account magnetic field effects and particle anisotropies, perturbations caused by the current collection process itself and contamination on electrode surfaces, the complexities of non-Maxwellian plasma distributions, and the temporal variability of the local plasma density, temperature, composition and fields. This set of variables is by no means all-inclusive, but it represents a collection of circumstances guaranteed to accompany experiments involving energetic particle beams, plasma discharges, chemical releases, wave injection and various events of controlled and uncontrolled spacecraft charging. Here, an attempt is made to synopsize these diagnostic challenges and frame them within a perspective that focuses on the physics under investigation and the requirements on the parameters to be measured. Examples include laboratory and spaceborne applications, with specific interest in dynamic and unstable plasma environments.

  10. Ultrafast Magnetism Dynamics Measure Using Tabletop Ultrafast EUV Sources

    SciTech Connect

    Silva, Thomas J.; Murnane, Margaret

    2013-08-21

    In our work to date, we made two significant advances. First we demonstrated element-selective demagnetization dynamics for the first time, with a record time resolution for x-ray probing of 55 fs. Second, in new work, we were able to probe the timescale of the exchange interaction in magnetic materials, also for the first time. Our measurements were made using the transverse magneto-optic Kerr effect (T-MOKE) geometry, since the reflectivity of a magnetic material changes with the direction of the magnetization vector of a surface. In our experiment, we periodically reversed the magnetization direction of a grating structure made of Permalloy (Ni80Fe20) using an external magnetic field. To achieve maximum contrast, we used HHG light spanning the M-shell (3p) absorption edges of Fe and Ni. Our characterization of the static magnetization of a Permalloy sample shows high magnetic asymmetry at photon energies just above and below the absorption edges at 55 eV and 65 eV, respectively. This result is in excellent agreement with measurements done on the same using a synchrotron source.

  11. Measuring dynamic kidney function in an undergraduate physiology laboratory.

    PubMed

    Medler, Scott; Harrington, Frederick

    2013-12-01

    Most undergraduate physiology laboratories are very limited in how they treat renal physiology. It is common to find teaching laboratories equipped with the capability for high-resolution digital recordings of physiological functions (muscle twitches, ECG, action potentials, respiratory responses, etc.), but most urinary laboratories still rely on a "dipstick" approach of urinalysis. Although this technique can provide some basic insights into the functioning of the kidneys, it overlooks the dynamic processes of filtration, reabsorption, and secretion. In the present article, we provide a straightforward approach of using renal clearance measurements to estimate glomerular filtration rate, fractional water reabsorption, glucose clearance, and other physiologically relevant parameters. The estimated values from our measurements in laboratory are in close agreement with those anticipated based on textbook parameters. For example, we found glomerular filtration rate to average 124 ± 45 ml/min, serum creatinine to be 1.23 ± 0.4 mg/dl, and fractional water reabsorption to be ∼96.8%. Furthermore, analyses for the class data revealed significant correlations between parameters like fractional water reabsorption and urine concentration, providing opportunities to discuss urine concentrating mechanisms and other physiological processes. The procedures outlined here are general enough that most undergraduate physiology laboratory courses should be able to implement them without difficulty. PMID:24292917

  12. Developing a New System to Measure Outcomes in a Service Coordination Program for Youth with Severe Emotional Disturbance

    ERIC Educational Resources Information Center

    Shannon, Lisa M.; Walker, Robert; Blevins, Michele

    2009-01-01

    This paper presents information on re-developing an outcome evaluation for a state-funded program providing service coordination utilizing wraparound to youth with severe emotional disturbance (SED) and their families. Originally funded by the Robert Wood Johnson Foundation, the Kentucky IMPACT program has existed statewide since 1990. Changing…

  13. Noninvasive, quantitative respirator fit testing through dynamic pressure measurement.

    PubMed

    Carpenter, D R; Willeke, K

    1988-10-01

    A new method has been invented for the noninvasive and quantitative determination of fit for a respirator. The test takes a few seconds and requires less expensive instrumentation than presently used for invasive testing. In this test, the breath is held at a negative pressure for a few seconds, and the leak-induced pressure decay inside the respirator cavity is monitored. A dynamic pressure sensor is attached to a modified cartridge of an air-purifying respirator or built into the respirator body or into the air supply line of an air-supplied respirator. The method is noninvasive in that the modified cartridge can be mounted onto any air-purifying respirator. The pressure decay during testing quantifies the airflow entered through the leak site. An equation has been determined which gives the air leakage as a function of pressure decay slope, respirator volume and the pressure differential during actual wear--all of which are determined by the dynamic pressure sensor. Thus, the ratio of air inhaled through the filters or via the air supply line to the leak rate is a measure of respirator fit, independent of aerosol deposition in the lung and aerosol distribution in the respirator cavity as found for quantitative fit testing with aerosols. The new method is shown to be independent of leak and sensor locations. The concentration and distribution of aerosols entered through the leak site is dependent only on the physical dimensions of the leak site and the air velocity in it, which can be determined independently.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:3189157

  14. Dynamic range measurement and calibration of SiPMs

    NASA Astrophysics Data System (ADS)

    Bretz, T.; Hebbeker, T.; Lauscher, M.; Middendorf, L.; Niggemann, T.; Schumacher, J.; Stephan, M.; Bueno, A.; Navas, S.; Ruiz, A. G.

    2016-03-01

    Photosensors have played and will continue to play an important role in high-energy and Astroparticle cutting-edge experiments. As of today, the most common photon detection device in use is the photomultiplier tube (PMT). However, we are witnessing rapid progress in the field and new devices now show very competitive features when compared to PMTs. Among those state-of-the-art photo detectors, silicon photomultipliers (SiPMs) are a relatively new kind of semiconductor whose potential is presently studied by many laboratories. Their characteristics make them a very attractive candidate for future Astroparticle physics experiments recording fluorescence and Cherenkov light, both in the atmosphere and on the ground. Such applications may require the measurement of the light flux on the sensor for the purpose of energy reconstruction. This is a complex task due to the limited dynamic range of SiPMs and the presence of thermal and correlated noise. In this work we study the response of three SiPM types in terms of delivered charge when exposed to light pulses in a broad range of intensities: from single photon to saturation. The influence of the pulse time duration and the SiPM over-voltage on the response are also quantified. Based on the observed behaviour, a method is presented to reconstruct the real number of photons impinging on the SiPM surface directly from the measured SiPM charge. A special emphasis is placed on the description of the methodology and experimental design used to perform the measurements.

  15. Free energy calculation using molecular dynamics simulation combined with the three-dimensional reference interaction site model theory. II. Thermodynamic integration along a spatial reaction coordinate.

    PubMed

    Miyata, Tatsuhiko; Ikuta, Yasuhiro; Hirata, Fumio

    2011-01-28

    We propose the thermodynamic integration along a spatial reaction coordinate using the molecular dynamics simulation combined with the three-dimensional reference interaction site model theory. This method provides a free energy calculation in solution along the reaction coordinate defined by the Cartesian coordinates of the solute atoms. The proposed method is based on the blue moon algorithm which can, in principle, handle any reaction coordinate as far as it is defined by the solute atom positions. In this article, we apply the present method to the complex formation process of the crown ether 18-Crown-6 (18C6) with the potassium ion in an aqueous solution. The separation between the geometric centers of these two molecules is taken to be the reaction coordinate for this system. The potential of mean force (PMF) becomes the maximum at the separation between the molecular centers being ∼4 Å, which can be identified as the free energy barrier in the process of the molecular recognition. In a separation further than the free energy barrier, the PMF is slightly reduced to exhibit a plateau. In the region closer than the free energy barrier, approach of the potassium ion to the center of 18C6 also decreases the PMF. When the potassium ion is accommodated at the center of 18C6, the free energy is lower by -5.7 ± 0.7 kcal/mol than that at the above mentioned plateau or converged state. By comparing the results with those from the free energy calculation along the coupling parameters obtained in our previous paper [T. Miyata, Y. Ikuta, and F. Hirata, J. Chem. Phys. 133, 044114 (2010)], it is found that the effective interaction in water between 18C6 and the potassium ion vanishes beyond the molecular-center-separation of 10 Å. Furthermore, the conformation of 18C6 is found to be significantly changed depending upon the 18C6-K(+) distance. A proper conformational sampling and an accurate solvent treatment are crucial for realizing the accurate PMF, and we believe

  16. Technology coordination

    NASA Technical Reports Server (NTRS)

    Hartman, Steven

    1992-01-01

    Viewgraphs on technology coordination are provided. Topics covered include: technology coordination process to date; goals; how the Office of Aeronautics and Space Technology (OAST) can support the Office of Space Science and Applications (OSSA); how OSSA can support OAST; steps to technology transfer; and recommendations.

  17. A Full Mission Simulator Study of Aircrew Performances: the Measurement of Crew Coordination and Decisionmaking Factors and Their Relationships to Flight Task Performances

    NASA Technical Reports Server (NTRS)

    Murphy, M. R.; Randle, R. J.; Tanner, T. A.; Frankel, R. M.; Goguen, J. A.; Linde, C.

    1984-01-01

    Sixteen three man crews flew a full mission scenario in an airline flight simulator. A high level of verbal interaction during instances of critical decision making was located. Each crew flew the scenario only once, without prior knowledge of the scenario problem. Following a simulator run and in accord with formal instructions, each of the three crew members independently viewed and commented on a videotape of their performance. Two check pilot observers rated pilot performance across all crews and, following each run, also commented on the video tape of the crew's performance. A linguistic analysis of voice transcript is made to provide assessment of crew coordination and decision making qualities. Measures of crew coordination and decision making factors are correlated with flight task performance measures.

  18. Circadian dynamics in measures of cortical excitation and inhibition balance.

    PubMed

    Chellappa, Sarah L; Gaggioni, Giulia; Ly, Julien Q M; Papachilleos, Soterios; Borsu, Chloé; Brzozowski, Alexandre; Rosanova, Mario; Sarasso, Simone; Luxen, André; Middleton, Benita; Archer, Simon N; Dijk, Derk-Jan; Massimini, Marcello; Maquet, Pierre; Phillips, Christophe; Moran, Rosalyn J; Vandewalle, Gilles

    2016-01-01

    Several neuropsychiatric and neurological disorders have recently been characterized as dysfunctions arising from a 'final common pathway' of imbalanced excitation to inhibition within cortical networks. How the regulation of a cortical E/I ratio is affected by sleep and the circadian rhythm however, remains to be established. Here we addressed this issue through the analyses of TMS-evoked responses recorded over a 29 h sleep deprivation protocol conducted in young and healthy volunteers. Spectral analyses of TMS-evoked responses in frontal cortex revealed non-linear changes in gamma band evoked oscillations, compatible with an influence of circadian timing on inhibitory interneuron activity. In silico inferences of cell-to-cell excitatory and inhibitory connectivity and GABA/Glutamate receptor time constant based on neural mass modeling within the Dynamic causal modeling framework, further suggested excitation/inhibition balance was under a strong circadian influence. These results indicate that circadian changes in EEG spectral properties, in measure of excitatory/inhibitory connectivity and in GABA/glutamate receptor function could support the maintenance of cognitive performance during a normal waking day, but also during overnight wakefulness. More generally, these findings demonstrate a slow daily regulation of cortical excitation/inhibition balance, which depends on circadian-timing and prior sleep-wake history. PMID:27651114

  19. Measurements of turbulent premixed flame dynamics using cinema stereoscopic PIV

    NASA Astrophysics Data System (ADS)

    Steinberg, Adam M.; Driscoll, James F.; Ceccio, Steven L.

    2008-06-01

    A new experimental method is described that provides high-speed movies of turbulent premixed flame wrinkling dynamics and the associated vorticity fields. This method employs cinema stereoscopic particle image velocimetry and has been applied to a turbulent slot Bunsen flame. Three-component velocity fields were measured with high temporal and spatial resolutions of 0.9 ms and 140 μm, respectively. The flame-front location was determined using a new multi-step method based on particle image gradients, which is described. Comparisons are made between flame fronts found with this method and simultaneous CH-PLIF images. These show that the flame contour determined corresponds well to the true location of maximum gas density gradient. Time histories of typical eddy-flame interactions are reported and several important phenomena identified. Outwardly rotating eddy pairs wrinkle the flame and are attenuated at they pass through the flamelet. Significant flame-generated vorticity is produced downstream of the wrinkled tip. Similar wrinkles are caused by larger groups of outwardly rotating eddies. Inwardly rotating pairs cause significant convex wrinkles that grow as the flame propagates. These wrinkles encounter other eddies that alter their behavior. The effects of the hydrodynamic and diffusive instabilities are observed and found to be significant contributors to the formation and propagation of wrinkles.

  20. Measurement of human pilot dynamic characteristics in flight simulation

    NASA Technical Reports Server (NTRS)

    Reedy, James T.

    1987-01-01

    Fast Fourier Transform (FFT) and Least Square Error (LSE) estimation techniques were applied to the problem of identifying pilot-vehicle dynamic characteristics in flight simulation. A brief investigation of the effects of noise, input bandwidth and system delay upon the FFT and LSE techniques was undertaken using synthetic data. Data from a piloted simulation conducted at NASA Ames Research Center was then analyzed. The simulation was performed in the NASA Ames Research Center Variable Stability CH-47B helicopter operating in fixed-basis simulator mode. The piloting task consisted of maintaining the simulated vehicle over a moving hover pad whose motion was described by a random-appearing sum of sinusoids. The two test subjects used a head-down, color cathode ray tube (CRT) display for guidance and control information. Test configurations differed in the number of axes being controlled by the pilot (longitudinal only versus longitudinal and lateral), and in the presence or absence of an important display indicator called an 'acceleration ball'. A number of different pilot-vehicle transfer functions were measured, and where appropriate, qualitatively compared with theoretical pilot- vehicle models. Some indirect evidence suggesting pursuit behavior on the part of the test subjects is discussed.