Science.gov

Sample records for coordination dynamics measuring

  1. Team coordination dynamics.

    PubMed

    Gorman, Jamie C; Amazeen, Polemnia G; Cooke, Nancy J

    2010-07-01

    Team coordination consists of both the dynamics of team member interaction and the environmental dynamics to which a team is subjected. Focusing on dynamics, an approach is developed that contrasts with traditional aggregate-static concepts of team coordination as characterized by the shared mental model approach. A team coordination order parameter was developed to capture momentary fluctuations in coordination. Team coordination was observed in three-person uninhabited air vehicle teams across two experimental sessions. The dynamics of the order parameter were observed under changes of a team familiarity control parameter. Team members returned for the second session to either the same (Intact) or different (Mixed) team. 'Roadblock' perturbations, or novel changes in the task environment, were introduced in order to probe the stability of team coordination. Nonlinear dynamic methods revealed differences that a traditional approach did not: Intact and Mixed team coordination dynamics looked very different; Mixed teams were more stable than Intact teams and explored the space of solutions without the need for correction. Stability was positively correlated with the number of roadblock perturbations that were overcome successfully. The novel and non-intuitive contribution of a dynamical analysis was that Mixed teams, who did not have a long history working together, were more adaptive. Team coordination dynamics carries new implications for traditional problems such as training adaptive teams.

  2. Coordination Dynamics in Cognitive Neuroscience

    PubMed Central

    Bressler, Steven L.; Kelso, J. A. Scott

    2016-01-01

    Many researchers and clinicians in cognitive neuroscience hold to a modular view of cognitive function in which the cerebral cortex operates by the activation of areas with circumscribed elementary cognitive functions. Yet an ongoing paradigm shift to a dynamic network perspective is underway. This new viewpoint treats cortical function as arising from the coordination dynamics within and between cortical regions. Cortical coordination dynamics arises due to the unidirectional influences imposed on a cortical area by inputs from other areas that project to it, combined with the projection reciprocity that characterizes cortical connectivity and gives rise to reentrant processing. As a result, cortical dynamics exhibits both segregative and integrative tendencies and gives rise to both cooperative and competitive relations within and between cortical areas that are hypothesized to underlie the emergence of cognition in brains. PMID:27695395

  3. Metal-coordination-driven dynamic heteroleptic architectures.

    PubMed

    De, Soumen; Mahata, Kingsuk; Schmittel, Michael

    2010-05-01

    Dynamic heteroleptic coordination at metal centres is quite common in Nature and often related to a specific biological function, such as in zinc finger proteins and in hemoglobin for oxygen transport. To achieve the required high heteroleptic fidelity, representative biological systems avail themselves of "intramolecular" multidentate coordination using the protein backbone as a "superligand". In contrast, dynamic heteroleptic coordination at a single metal centre in solution requires to bind different freely exchanging ligands under thermodynamic control. In this tutorial review we present the emerging principles of how to assemble dissimilar ligands at dynamically exchanging metal centres, with a particular emphasis on using the precepts for the fabrication of heteroleptic supramolecular assemblies in solution.

  4. Concurrent Cognitive Task Modulates Coordination Dynamics

    ERIC Educational Resources Information Center

    Pellecchia, Geraldine L.; Shockley, Kevin; Turvey, M. T.

    2005-01-01

    Does a concurrent cognitive task affect the dynamics of bimanual rhythmic coordination? In-phase coordination was performed under manipulations of phase detuning and movement frequency and either singly or in combination with an arithmetic task. Predicted direction-specific shifts in stable relative phase from 0 degrees due to detuning and…

  5. Equipartition Principle for Internal Coordinate Molecular Dynamics.

    PubMed

    Jain, Abhinandan; Park, In-Hee; Vaidehi, Nagarajan

    2012-08-14

    The principle of equipartition of (kinetic) energy for all-atom Cartesian molecular dynamics states that each momentum phase space coordinate on the average has ½kT of kinetic energy in a canonical ensemble. This principle is used in molecular dynamics simulations to initialize velocities, and to calculate statistical properties such as entropy. Internal coordinate molecular dynamics (ICMD) models differ from Cartesian models in that the overall kinetic energy depends on the generalized coordinates and includes cross-terms. Due to this coupled structure, no such equipartition principle holds for ICMD models. In this paper we introduce non-canonical modal coordinates to recover some of the structural simplicity of Cartesian models and develop a new equipartition principle for ICMD models. We derive low-order recursive computational algorithms for transforming between the modal and physical coordinates. The equipartition principle in modal coordinates provides a rigorous method for initializing velocities in ICMD simulations thus replacing the ad hoc methods used until now. It also sets the basis for calculating conformational entropy using internal coordinates.

  6. Neuroimaging Coordination Dynamics in the Sport Sciences

    PubMed Central

    Jantzen, Kelly J.; Oullier, Olivier; Kelso, J.A. Scott

    2008-01-01

    Key methodological issues for designing, analyzing, and interpreting neuroimaging experiments are presented from the perspective of the framework of Coordination Dynamics. To this end, a brief overview of Coordination Dynamics is introduced, including the main concepts of control parameters and collective variables, theoretical modeling, novel experimental paradigms, and cardinal empirical findings. Basic conceptual and methodological issues for the design and implementation of coordination experiments in the context of neuroimaging are discussed. The paper concludes with a presentation of neuroimaging findings central to understanding the neural basis of coordination and addresses their relevance for the sport sciences. The latter include but are not restricted to learning and practice-related issues, the role of mental imagery, and the recovery of function following brain injury. PMID:18602998

  7. Dynamical modelling of coordinated multiple robot systems

    NASA Technical Reports Server (NTRS)

    Hayati, Samad

    1987-01-01

    The state of the art in the modeling of the dynamics of coordinated multiple robot manipulators is summarized and various problems related to this subject are discussed. It is recognized that dynamics modeling is a component used in the design of controllers for multiple cooperating robots. As such, the discussion addresses some problems related to the control of multiple robots. The techniques used to date in the modeling of closed kinematic chains are summarized. Various efforts made to date for the control of coordinated multiple manipulators is summarized.

  8. Coordinated supply chain dynamic production planning model

    NASA Astrophysics Data System (ADS)

    Chandra, Charu; Grabis, Janis

    2001-10-01

    Coordination of different and often contradicting interests of individual supply chain members is one of the important issues in supply chain management because the individual members can not succeed without success of the supply chain and vice versa. This paper investigates a supply chain dynamic production planning problem with emphasis on coordination. A planning problem is formally described using a supply chain kernel, which defines supply chain configuration, management policies, available resources and objectives both at supply chain or macro and supply chain member or micro levels. The coordinated model is solved in order to balance decisions made at the macro and micro levels and members' profitability is used as the coordination criterion. The coordinated model is used to determine inventory levels and production capacity across the supply chain. Application of the coordinated model distributes costs burden uniformly among supply chain members and preserves overall efficiency of the supply chain. Influence of the demand series uncertainty is investigated. The production planning model is a part of the integrated supply chain decision modeling system, which is shared among the supply chain members across the Internet.

  9. The coordination dynamics of social neuromarkers.

    PubMed

    Tognoli, Emmanuelle; Kelso, J A Scott

    2015-01-01

    Social behavior is a complex integrative function that entails many aspects of the brain's sensory, cognitive, emotional and movement capacities. Its neural processes are seldom simultaneous but occur according to precise spatiotemporal choreographies, manifested by the coordination of their oscillations within and between brains. Methods with good temporal resolution can help to identify so-called "neuromarkers" of social function and aid in disentangling the dynamical architecture of social brains. In our ongoing research, we have used dual-electroencephalography (EEG) to study neuromarker dynamics during synchronic interactions in which pairs of subjects coordinate behavior spontaneously and intentionally (social coordination) and during diachronic transactions that require subjects to perceive or behave in turn (action observation, delayed imitation). In this paper, after outlining our dynamical approach to the neurophysiological basis of social behavior, we examine commonalities and differences in the neuromarkers that are recruited for both kinds of tasks. We find the neuromarker landscape to be task-specific: synchronic paradigms of social coordination reveal medial mu, alpha and the phi complex as contributing neuromarkers. Diachronic tasks recruit alpha as well, in addition to lateral mu rhythms and the newly discovered nu and kappa rhythms whose functional significance is still unclear. Social coordination, observation, and delayed imitation share commonality of context: in each of our experiments, subjects exchanged information through visual perception and moved in similar ways. Nonetheless, there was little overlap between their neuromarkers, a result that hints strongly of task-specific neural mechanisms for social behavior. The only neuromarker that transcended both synchronic and diachronic social behaviors was the ubiquitous alpha rhythm, which appears to be a key signature of visually-mediated social behaviors. The present paper is both an entry

  10. The coordination dynamics of social neuromarkers

    PubMed Central

    Tognoli, Emmanuelle; Kelso, J. A. Scott

    2015-01-01

    Social behavior is a complex integrative function that entails many aspects of the brain’s sensory, cognitive, emotional and movement capacities. Its neural processes are seldom simultaneous but occur according to precise spatiotemporal choreographies, manifested by the coordination of their oscillations within and between brains. Methods with good temporal resolution can help to identify so-called “neuromarkers” of social function and aid in disentangling the dynamical architecture of social brains. In our ongoing research, we have used dual-electroencephalography (EEG) to study neuromarker dynamics during synchronic interactions in which pairs of subjects coordinate behavior spontaneously and intentionally (social coordination) and during diachronic transactions that require subjects to perceive or behave in turn (action observation, delayed imitation). In this paper, after outlining our dynamical approach to the neurophysiological basis of social behavior, we examine commonalities and differences in the neuromarkers that are recruited for both kinds of tasks. We find the neuromarker landscape to be task-specific: synchronic paradigms of social coordination reveal medial mu, alpha and the phi complex as contributing neuromarkers. Diachronic tasks recruit alpha as well, in addition to lateral mu rhythms and the newly discovered nu and kappa rhythms whose functional significance is still unclear. Social coordination, observation, and delayed imitation share commonality of context: in each of our experiments, subjects exchanged information through visual perception and moved in similar ways. Nonetheless, there was little overlap between their neuromarkers, a result that hints strongly of task-specific neural mechanisms for social behavior. The only neuromarker that transcended both synchronic and diachronic social behaviors was the ubiquitous alpha rhythm, which appears to be a key signature of visually-mediated social behaviors. The present paper is both an

  11. Coordination dynamics in Parkinson's disease patients and healthy subjects quantified by the coordination dynamics recording method and sEMG.

    PubMed

    Schalow, G; Pääsuke, M; Ereline, J; Gapeyeva, H

    2003-12-01

    Coordination dynamics were measured in Parkinson's disease patients to quantify central nervous system (CNS) dysfunction. The low-load coordination dynamics in the patients were impaired by 56% for forward and 44% for backward moving in comparison to a control group of similar age. Exercising at higher load was only partly possible. When the disease preferentially affected one side of the body, the coordination dynamics were worse for the affected side. A dexterity test showed that coordination of hand and arm movements could be improved in the short-term memory when exercising on the special coordination dynamics recording and therapy device. Simultaneously taken surface EMG (sEMG) showed that the motor pattern was impaired in the Parkinson's disease patients. sEMG recordings showed further that the fast fatigable muscle fibre activation was impaired. FF-type muscle fibres were already activated for low load in one and not at all in another muscle. In conclusion, coordination between motoneuron firings and between arm and leg movements were found to be impaired in Parkinson's disease patients.

  12. CODA: Coordinated Observations of Dynamics in Aurora

    NASA Technical Reports Server (NTRS)

    Larsen, M. F.

    2003-01-01

    The grant funds were provided to carry out chemical tracer wind and turbulence measurements in the mesosphere and lower thermosphere as part of the Coordinated Observations of Dynamics in Aurora (CODA) experiment for which Dr. Andy Christensen of the Aerospace Corp. was the Principal Investigator. Clemson University was a co-investigator institution on the project and was tasked with designing, building, and testing a total of four chemical tracer release payloads which were used to release trimethyl aluminum (TMA) to measure the winds and turbulent diffusion. All four payloads were flown from the rocket range at Poker Flat, Alaska, in support of instrumented payloads flown from the same location. The CODA experiment was designed to investigate the changes in the chemical composition in the lower thermosphere during an auroral substorm event. In particular, the objective was to determine the relative importance of two competing mechanisms. The first mechanism is associated with the advection of air from the polar cap into the auroral oval. A flow in that direction is typical in the postmidnight sector of the oval. As the air moves from the region of negligible forcing in the polar cap to the region of strong forcing and heating in the oval, changes in the composition are expected to occur. Alternatively, enhanced local mixing will also cause such changes. Since the auroral forcing accelerates the neutral winds in the lower E region, but not at lower altitudes, the forcing results in large shears that can be large enough to be unstable in the Richardson number sense. The unstable shears are expected to generate turbulence and therefore enhanced mixing. Such mixing will also create composition changes similar to what is observed. In the CODA experiment an instrumented payload designed and built by the Aerospace Corporation was used to measure the composition and plasma parameters needed to define the auroral forcing. In addition, three chemical tracer payloads were

  13. Highly accurate articulated coordinate measuring machine

    DOEpatents

    Bieg, Lothar F.; Jokiel, Jr., Bernhard; Ensz, Mark T.; Watson, Robert D.

    2003-12-30

    Disclosed is a highly accurate articulated coordinate measuring machine, comprising a revolute joint, comprising a circular encoder wheel, having an axis of rotation; a plurality of marks disposed around at least a portion of the circumference of the encoder wheel; bearing means for supporting the encoder wheel, while permitting free rotation of the encoder wheel about the wheel's axis of rotation; and a sensor, rigidly attached to the bearing means, for detecting the motion of at least some of the marks as the encoder wheel rotates; a probe arm, having a proximal end rigidly attached to the encoder wheel, and having a distal end with a probe tip attached thereto; and coordinate processing means, operatively connected to the sensor, for converting the output of the sensor into a set of cylindrical coordinates representing the position of the probe tip relative to a reference cylindrical coordinate system.

  14. Multistability and metastability: understanding dynamic coordination in the brain

    PubMed Central

    Kelso, J. A. Scott

    2012-01-01

    Multistable coordination dynamics exists at many levels, from multifunctional neural circuits in vertebrates and invertebrates to large-scale neural circuitry in humans. Moreover, multistability spans (at least) the domains of action and perception, and has been found to place constraints upon, even dictating the nature of, intentional change and the skill-learning process. This paper reviews some of the key evidence for multistability in the aforementioned areas, and illustrates how it has been measured, modelled and theoretically understood. It then suggests how multistability—when combined with essential aspects of coordination dynamics such as instability, transitions and (especially) metastability—provides a platform for understanding coupling and the creative dynamics of complex goal-directed systems, including the brain and the brain–behaviour relation. PMID:22371613

  15. Internal coordinate molecular dynamics: a foundation for multiscale dynamics.

    PubMed

    Vaidehi, Nagarajan; Jain, Abhinandan

    2015-01-29

    Internal coordinates such as bond lengths, bond angles, and torsion angles (BAT) are natural coordinates for describing a bonded molecular system. However, the molecular dynamics (MD) simulation methods that are widely used for proteins, DNA, and polymers are based on Cartesian coordinates owing to the mathematical simplicity of the equations of motion. However, constraints are often needed with Cartesian MD simulations to enhance the conformational sampling. This makes the equations of motion in the Cartesian coordinates differential-algebraic, which adversely impacts the complexity and the robustness of the simulations. On the other hand, constraints can be easily placed in BAT coordinates by removing the degrees of freedom that need to be constrained. Thus, the internal coordinate MD (ICMD) offers an attractive alternative to Cartesian coordinate MD for developing multiscale MD method. The torsional MD method is a special adaptation of the ICMD method, where all the bond lengths and bond angles are kept rigid. The advantages of ICMD simulation methods are the longer time step size afforded by freezing high frequency degrees of freedom and performing a conformational search in the more important low frequency torsional degrees of freedom. However, the advancements in the ICMD simulations have been slow and stifled by long-standing mathematical bottlenecks. In this review, we summarize the recent mathematical advancements we have made based on spatial operator algebra, in developing a robust long time scale ICMD simulation toolkit useful for various applications. We also present the applications of ICMD simulations to study conformational changes in proteins and protein structure refinement. We review the advantages of the ICMD simulations over the Cartesian simulations when used with enhanced sampling methods and project the future use of ICMD simulations in protein dynamics.

  16. Internal Coordinate Molecular Dynamics: A Foundation for Multiscale Dynamics

    PubMed Central

    2015-01-01

    Internal coordinates such as bond lengths, bond angles, and torsion angles (BAT) are natural coordinates for describing a bonded molecular system. However, the molecular dynamics (MD) simulation methods that are widely used for proteins, DNA, and polymers are based on Cartesian coordinates owing to the mathematical simplicity of the equations of motion. However, constraints are often needed with Cartesian MD simulations to enhance the conformational sampling. This makes the equations of motion in the Cartesian coordinates differential-algebraic, which adversely impacts the complexity and the robustness of the simulations. On the other hand, constraints can be easily placed in BAT coordinates by removing the degrees of freedom that need to be constrained. Thus, the internal coordinate MD (ICMD) offers an attractive alternative to Cartesian coordinate MD for developing multiscale MD method. The torsional MD method is a special adaptation of the ICMD method, where all the bond lengths and bond angles are kept rigid. The advantages of ICMD simulation methods are the longer time step size afforded by freezing high frequency degrees of freedom and performing a conformational search in the more important low frequency torsional degrees of freedom. However, the advancements in the ICMD simulations have been slow and stifled by long-standing mathematical bottlenecks. In this review, we summarize the recent mathematical advancements we have made based on spatial operator algebra, in developing a robust long time scale ICMD simulation toolkit useful for various applications. We also present the applications of ICMD simulations to study conformational changes in proteins and protein structure refinement. We review the advantages of the ICMD simulations over the Cartesian simulations when used with enhanced sampling methods and project the future use of ICMD simulations in protein dynamics. PMID:25517406

  17. Development of Measures of Crew Coordination

    DTIC Science & Technology

    1992-07-01

    ARI Research Note 92-68 AD-A255 384 /111I111111111111111 0/ il i~ilI Development of Measures of Crew Coordination Robert Simon, Daniel T. Risser , and...Crew Coordination 62785A ,_ 790 G. AUTHORt- 1211 Simon, Robert; Risser , Daniel T.; and Pawlik, Eugene A., C03 Sr. . E•ORM II• t ., " >, -. •_ •.. -: L...position. If the white light Is used. night vision will be impaired for several minutes. Therefore, exercise extra caution if flight Is resumed

  18. Dynamic similarity promotes interpersonal coordination in joint action.

    PubMed

    Słowiński, Piotr; Zhai, Chao; Alderisio, Francesco; Salesse, Robin; Gueugnon, Mathieu; Marin, Ludovic; Bardy, Benoit G; di Bernardo, Mario; Tsaneva-Atanasova, Krasimira

    2016-03-01

    Human movement has been studied for decades, and dynamic laws of motion that are common to all humans have been derived. Yet, every individual moves differently from everyone else (faster/slower, harder/smoother, etc.). We propose here an index of such variability, namely an individual motor signature (IMS) able to capture the subtle differences in the way each of us moves. We show that the IMS of a person is time-invariant and that it significantly differs from those of other individuals. This allows us to quantify the dynamic similarity, a measure of rapport between dynamics of different individuals' movements, and demonstrate that it facilitates coordination during interaction. We use our measure to confirm a key prediction of the theory of similarity that coordination between two individuals performing a joint-action task is higher if their motions share similar dynamic features. Furthermore, we use a virtual avatar driven by an interactive cognitive architecture based on feedback control theory to explore the effects of different kinematic features of the avatar motion on coordination with human players.

  19. Dynamic similarity promotes interpersonal coordination in joint action

    PubMed Central

    Słowiński, Piotr; Zhai, Chao; Alderisio, Francesco; Salesse, Robin; Gueugnon, Mathieu; Marin, Ludovic; Bardy, Benoit G.; di Bernardo, Mario; Tsaneva-Atanasova, Krasimira

    2016-01-01

    Human movement has been studied for decades, and dynamic laws of motion that are common to all humans have been derived. Yet, every individual moves differently from everyone else (faster/slower, harder/smoother, etc.). We propose here an index of such variability, namely an individual motor signature (IMS) able to capture the subtle differences in the way each of us moves. We show that the IMS of a person is time-invariant and that it significantly differs from those of other individuals. This allows us to quantify the dynamic similarity, a measure of rapport between dynamics of different individuals' movements, and demonstrate that it facilitates coordination during interaction. We use our measure to confirm a key prediction of the theory of similarity that coordination between two individuals performing a joint-action task is higher if their motions share similar dynamic features. Furthermore, we use a virtual avatar driven by an interactive cognitive architecture based on feedback control theory to explore the effects of different kinematic features of the avatar motion on coordination with human players. PMID:27009178

  20. The coordination dynamics of mobile conjugate reinforcement.

    PubMed

    Kelso, J A Scott; Fuchs, Armin

    2016-02-01

    What we know about infant learning and memory is founded largely on systematic studies by the late Carolyn Rovee-Collier (1942-2014) and her associates of a phenomenon called mobile conjugate reinforcement. Experiments show that when a ribbon is attached from a 3-month-old infant's foot to a mobile suspended overhead the baby quickly realizes it can make the mobile move. The mobile, which offers interesting sights and sounds, responds conjugately to the baby's vigorous kicks which increase in rate by a factor of 3-4. In this paper, using the concepts, methods and tools of coordination dynamics, we present a theoretical model which reproduces the experimental observations of Rovee-Collier and others and predicts a number of additional features that can be experimentally tested. The model is a dynamical system consisting of three equations, one for the baby's leg movements, one for the jiggling motion of the mobile and one for the functional coupling between the two. A key mechanism in the model is positive feedback which is shown to depend sensitively on bifurcation parameters related to the infant's level of attention and inertial properties of the mobile. The implications of our model for the dynamical (and developmental) origins of agency are discussed.

  1. Measurement of Pinion Type Cutter Using Coordinate Measuring Machine

    NASA Astrophysics Data System (ADS)

    Liu, Zongxian; Tamura, Hisashi; Kawasaki, Kazumasa; Mitome, Ken-Ichi

    A method for measuring a pinion type cutter using a coordinate measuring machine is proposed. In this method, the cutting edge profile of the cutter is indirectly measured as the intersecting curve between the flank of tool and the cutting face. Left and right side flanks of the cutter are considered to be the tooth surfaces of two different involute helical gears. The coordinates of many points on the tooth surface and the face are measured using a coordinate measuring machine. The tooth surface and the face are estimated from the measured data by the method of least squares. The cutting edge profile is calculated from the estimated tooth surface and the face. The cutting edge is moved helically and it forms the tooth surface of the actual imaginary gear. A pressure angle of this gear can be calculated. Pressure angle error of the pinion type cutter is that of the imaginary gear.

  2. Phase Retrieval Techniques In Coordinates Measurement

    SciTech Connect

    Harizanova, J. I.; Stoykova, E. V.; Sainov, V. C.

    2007-04-23

    A precise pattern projection profilometry for three-dimensional shape measurements with different methods of fringe generation is presented. The application of phase-shifting algorithm along with two-spacing illumination allow for phase retrieval and estimation of relative and absolute coordinates of the tested samples. The following experimental approaches for fringe generation are investigated: interferometric approach based on a classical Michelson interferometer, digital computation with a DMD projection and light modulation by a sinusoidal phase grating. The theoretical background, experimental results as well as comparison of the applied generation methods are analyzed. The obtained outcomes successfully display the applicability of this technique for surface profile measurement. The application of the proposed techniques for remote, non-destructive in-situ inspection of real objects from cultural heritage is discussed.

  3. Measurement, coordination, and the relativized a priori

    NASA Astrophysics Data System (ADS)

    Padovani, Flavia

    2015-11-01

    The problem of measurement is a central issue in the epistemology and methodology of the physical sciences. In recent literature on scientific representation, large emphasis has been put on the "constitutive role" played by measurement procedures as forms of representation. Despite its importance, this issue hardly finds any mention in writings on constitutive principles, viz. in Michael Friedman's account of relativized a priori principles. This issue, instead, was at the heart of Reichenbach's analysis of coordinating principles that has inspired Friedman's interpretation. This paper suggests that these procedures should have a part in an account of constitutive principles of science, and that they could be interpreted following the intuition originally present (but ultimately not fully developed) in Reichenbach's early work.

  4. Specimen coordinate automated measuring machine/fiducial automated measuring machine

    SciTech Connect

    Hedglen, Robert E.; Jacket, Howard S.; Schwartz, Allan I.

    1991-01-01

    The Specimen coordinate Automated Measuring Machine (SCAMM) and the Fiducial Automated Measuring Machine (FAMM) is a computer controlled metrology system capable of measuring length, width, and thickness, and of locating fiducial marks. SCAMM and FAMM have many similarities in their designs, and they can be converted from one to the other without taking them out of the hot cell. Both have means for: supporting a plurality of samples and a standard; controlling the movement of the samples in the +/- X and Y directions; determining the coordinates of the sample; compensating for temperature effects; and verifying the accuracy of the measurements and repeating as necessary. SCAMM and FAMM are designed to be used in hot cells.

  5. Dynamical methods for evaluating the time-dependent unfolding of social coordination in children with autism

    PubMed Central

    Fitzpatrick, Paula; Diorio, Rachel; Richardson, Michael J.; Schmidt, R. C.

    2013-01-01

    Children with Autism Spectrum Disorder (ASD) suffer from numerous impairments in social interaction that affect both their mental and bodily coordination with others. We explored here whether interpersonal motor coordination may be an important key for understanding the profound social problems of children with ASD. We employed a set of experimental techniques to evaluate not only traditional cognitive measures of social competence but also the dynamical structure of social coordination by using dynamical measures of social motor coordination and analyzing the time series records of behavior. Preliminary findings suggest that children with ASD were equivalent to typically developing children on many social performance outcome measures. However, significant relationships were found between cognitive social measures (e.g., intentionality) and dynamical social motor measures. In addition, we found that more perceptually-based measures of social coordination were not associated with social motor coordination. These findings suggest that social coordination may not be a unitary construct and point to the promise of this multi-method and process-oriented approach to analyzing social coordination as an important pathway for understanding ASD-specific social deficits. PMID:23580133

  6. Framework for coordination of activities in dynamic situations

    NASA Astrophysics Data System (ADS)

    Franke, Jörn; Charoy, François; El Khoury, Paul

    2013-02-01

    Recent disasters, such as Hurricane Katrina in 2005, have shown several issues for the coordination of human activities in these dynamic situations. Contemporary tools for the coordination used in the disaster response, such as e-mail, Whiteboards or phones, only allow for unstructured coordination, which can cause coordination problems. Hence, we discuss about the current information systems for coordinating the activities in a structured manner and identify their weaknesses in the context of a process modelling effort conducted together with experienced disaster managers. Afterwards, we propose a framework for coordination of activities in dynamic situations. The framework presented in this paper has been implemented as an extension to an open collaboration service. This shows how it can be used in the context of other tools required for disaster response management, such as maps, pictures or videos of the situation. The work described here is the foundation for enabling inter-organisational coordination of activities relevant in other domains, e.g. enterprise support processes, production processes or distributed software development projects. Furthermore, comments by disaster managers show that the concepts are relevant for their work. The expected impact is a more effective and efficient coordination of human activities in dynamic situations by structuring what needs to be coordinated.

  7. Method to describe stochastic dynamics using an optimal coordinate.

    PubMed

    Krivov, Sergei V

    2013-12-01

    A general method to describe the stochastic dynamics of Markov processes is suggested. The method aims to solve three related problems: the determination of an optimal coordinate for the description of stochastic dynamics; the reconstruction of time from an ensemble of stochastic trajectories; and the decomposition of stationary stochastic dynamics into eigenmodes which do not decay exponentially with time. The problems are solved by introducing additive eigenvectors which are transformed by a stochastic matrix in a simple way - every component is translated by a constant distance. Such solutions have peculiar properties. For example, an optimal coordinate for stochastic dynamics with detailed balance is a multivalued function. An optimal coordinate for a random walk on a line corresponds to the conventional eigenvector of the one-dimensional Dirac equation. The equation for the optimal coordinate in a slowly varying potential reduces to the Hamilton-Jacobi equation for the action function.

  8. Higher-Order Synaptic Interactions Coordinate Dynamics in Recurrent Networks

    PubMed Central

    Chambers, Brendan; MacLean, Jason N.

    2016-01-01

    Linking synaptic connectivity to dynamics is key to understanding information processing in neocortex. Circuit dynamics emerge from complex interactions of interconnected neurons, necessitating that links between connectivity and dynamics be evaluated at the network level. Here we map propagating activity in large neuronal ensembles from mouse neocortex and compare it to a recurrent network model, where connectivity can be precisely measured and manipulated. We find that a dynamical feature dominates statistical descriptions of propagating activity for both neocortex and the model: convergent clusters comprised of fan-in triangle motifs, where two input neurons are themselves connected. Fan-in triangles coordinate the timing of presynaptic inputs during ongoing activity to effectively generate postsynaptic spiking. As a result, paradoxically, fan-in triangles dominate the statistics of spike propagation even in randomly connected recurrent networks. Interplay between higher-order synaptic connectivity and the integrative properties of neurons constrains the structure of network dynamics and shapes the routing of information in neocortex. PMID:27542093

  9. Challenges for the understanding of the dynamics of social coordination

    PubMed Central

    Lagarde, Julien

    2013-01-01

    The way people interact can be examined by looking at the way they move relative to each other. Seeking the principles behind those interactions have consequences potentially related to any type of interpersonal function, far beyond the so-called “motor” processes typically associated with the study of movements, be it perceptive, cognitive, affective, pragmatic, or epistemic. Here, we present the way the framework of coordination dynamics define and addresses the interactive actions in a dyad. We first introduce the basics of pattern formation as the roots of the theoretical approach of coordination dynamics, and then the way this framework may contribute to establish a solution to classify behaviors. Thereafter we review promising empirical results on the dynamics of interpersonal coordination, and finally discuss were to go next to decipher the way the coordination between two people and the way each individual contribute may be disentangled. PMID:24130526

  10. Dynamic self-assembly of coordination polymers in aqueous solution.

    PubMed

    Li, Wen; Kim, Yongju; Li, Jingfang; Lee, Myongsoo

    2014-08-07

    The construction of supramolecular polymers has been intensively pursued because the nanostructures formed through weak non-covalent interactions can be triggered by external stimuli leading to smart materials and sensors. Self-assemblies of coordination polymers consisting of metal ions and organic ligands in aqueous solution also provide particular contributions in this area. The main motivation for developing those coordination polymers originates from the value-added combination between metal ions and ligands. This review highlights the recent progress of the dynamic self-assembly of coordination polymers that result from the sophisticated molecular design, towards fabricating stimuli-responsive systems and bio-related materials. Dynamic structural changes and switchable physical properties triggered by various stimuli are summarized. Finally, the outlook for aqueous nanostructures originated from the dynamic self-assembly of coordination polymers is also presented.

  11. Minimal Coordinate Formulation of Contact Dynamics in Operational Space

    NASA Technical Reports Server (NTRS)

    Jain, Abhinandan; Crean, Cory; Ku, Calvin; Myint, Steven; vonBremen, Hubertus

    2012-01-01

    In recent years, complementarity techniques have been developed for modeling non-smooth contact and collision dynamics problems for multi-link robotic systems. Normally, in this approach, a linear complementarity problem (LCP) is set up using 6n non-minimal coordinates for a system with n links together with all the unilateral constraints and inter-link bilateral constraints on the system. In this paper, we use operational space dynamics to develop a complementarity formulation for contact and collision dynamics that uses minimal coordinates. The use of such non-redundant coordinates results in much smaller size LCP problems and the automatic enforcement of the inter-link bilateral constraints. Furthermore, we exploit operational space low-order computational algorithms to overcome some of the bottlenecks in using minimal coordinates.

  12. Appendage modal coordinate truncation criteria in hybrid coordinate dynamic analysis. [for spacecraft attitude control

    NASA Technical Reports Server (NTRS)

    Likins, P.; Ohkami, Y.; Wong, C.

    1976-01-01

    The paper examines the validity of the assumption that certain appendage-distributed (modal) coordinates can be truncated from a system model without unacceptable degradation of fidelity in hybrid coordinate dynamic analysis for attitude control of spacecraft with flexible appendages. Alternative truncation criteria are proposed and their interrelationships defined. Particular attention is given to truncation criteria based on eigenvalues, eigenvectors, and controllability and observability. No definitive resolution of the problem is advanced, and exhaustive study is required to obtain ultimate truncation criteria.

  13. Combination of a vision system and a coordinate measuring machine for rapid coordinate metrology

    NASA Astrophysics Data System (ADS)

    Qu, Yufu; Pu, Zhaobang; Liu, Guodong

    2002-09-01

    This paper presents a novel methodology that integrates a vision system and a coordinate measuring machine for rapid coordinate metrology. Rapid acquisition of coordinate data from parts having tiny dimension, complex geometry and soft or fragile material has many applications. Typical examples include Large Scale Integrated circuit, glass or plastic part measurement, and reverse engineering in rapid product design and realization. In this paper, a novel approach to a measuring methodology for a vision integrated coordinate measuring system is developed and demonstrated. The vision coordinate measuring system is characterized by an integrated use of a high precision coordinate measuring machine (CMM), a vision system, advanced computational software, and the associated electronics. The vision system includes a charge-coupled device (CCD) camera, a self-adapt brightness power, and a graphics workstation with an image processing board. The vision system along with intelligent feature recognition and auto-focus algorithms provides the feature point space coordinate of global part profile after the system has been calibrated. The measured data may be fitted to geometry element of part profile. The obtained results are subsequently used to compute parameters consist of curvature radius, distance, shape error and surface reconstruction. By integrating the vision system with the CMM, a highly automated, high speed, 3D coordinate acquisition system is developed. It has potential applications in a whole spectrum of manufacturing problems with a major impact on metrology, inspection, and reverse engineering.

  14. Virtual Partner Interaction (VPI): Exploring Novel Behaviors via Coordination Dynamics

    PubMed Central

    Kelso, J. A. Scott; de Guzman, Gonzalo C.; Reveley, Colin; Tognoli, Emmanuelle

    2009-01-01

    Inspired by the dynamic clamp of cellular neuroscience, this paper introduces VPI—Virtual Partner Interaction—a coupled dynamical system for studying real time interaction between a human and a machine. In this proof of concept study, human subjects coordinate hand movements with a virtual partner, an avatar of a hand whose movements are driven by a computerized version of the Haken-Kelso-Bunz (HKB) equations that have been shown to govern basic forms of human coordination. As a surrogate system for human social coordination, VPI allows one to examine regions of the parameter space not typically explored during live interactions. A number of novel behaviors never previously observed are uncovered and accounted for. Having its basis in an empirically derived theory of human coordination, VPI offers a principled approach to human-machine interaction and opens up new ways to understand how humans interact with human-like machines including identification of underlying neural mechanisms. PMID:19492044

  15. Identification of simple reaction coordinates from complex dynamics

    NASA Astrophysics Data System (ADS)

    McGibbon, Robert T.; Husic, Brooke E.; Pande, Vijay S.

    2017-01-01

    Reaction coordinates are widely used throughout chemical physics to model and understand complex chemical transformations. We introduce a definition of the natural reaction coordinate, suitable for condensed phase and biomolecular systems, as a maximally predictive one-dimensional projection. We then show that this criterion is uniquely satisfied by a dominant eigenfunction of an integral operator associated with the ensemble dynamics. We present a new sparse estimator for these eigenfunctions which can search through a large candidate pool of structural order parameters and build simple, interpretable approximations that employ only a small number of these order parameters. Example applications with a small molecule's rotational dynamics and simulations of protein conformational change and folding show that this approach can filter through statistical noise to identify simple reaction coordinates from complex dynamics.

  16. Large-deformation modal coordinates for nonrigid vehicle dynamics

    NASA Technical Reports Server (NTRS)

    Likins, P. W.; Fleischer, G. E.

    1972-01-01

    The derivation of minimum-dimension sets of discrete-coordinate and hybrid-coordinate equations of motion of a system consisting of an arbitrary number of hinge-connected rigid bodies assembled in tree topology is presented. These equations are useful for the simulation of dynamical systems that can be idealized as tree-like arrangements of substructures, with each substructure consisting of either a rigid body or a collection of elastically interconnected rigid bodies restricted to small relative rotations at each connection. Thus, some of the substructures represent elastic bodies subjected to small strains or local deformations, but possibly large gross deformations, in the hybrid formulation, distributed coordinates referred to herein as large-deformation modal coordinates, are used for the deformations of these substructures. The equations are in a form suitable for incorporation into one or more computer programs to be used as multipurpose tools in the simulation of spacecraft and other complex electromechanical systems.

  17. Lags in measuring eye-hand coordination.

    PubMed

    Hill, Liam J B; Culmer, Peter R; Mon-Williams, Mark

    2014-07-30

    We challenge a number of the claims for novelty and innovation made in a recent published paper (Lee et al., 2014) with regard to a computerised methodology that these authors present for assessing eye-hand coordination (EHC). Published work on similar pre-existing computerised systems is discussed and arguments made for these alternative systems being equal, if not superior, in terms of their innovativeness. The commentary does not dispute the usefulness of systems such as the one described by Lee et al. Rather, in the interests of scholarship it provides an accompanying insight into the significant scholarly contributions previously, and contemporaneously, being made by other research groups working in this area.

  18. Internal coordinate density of state from molecular dynamics simulation.

    PubMed

    Lai, Pin-Kuang; Lin, Shiang-Tai

    2015-03-30

    The vibrational density of states (DoS), calculated from the Fourier transform of the velocity autocorrelation function, provides profound information regarding the structure and dynamic behavior of a system. However, it is often difficult to identify the exact vibrational mode associated with a specific frequency if the DoS is determined based on velocities in Cartesian coordinates. Here, the DoS is determined based on velocities in internal coordinates, calculated from Cartesian atomic velocities using a generalized Wilson's B-matrix. The DoS in internal coordinates allows for the correct detection of free dihedral rotations that may be mistaken as hindered rotation in Cartesian DoS. Furthermore, the pronounced enhancement of low frequency modes in Cartesian DoS for macromolecules should be attributed to the coupling of dihedral and angle motions. The internal DoS, thus deconvolutes the internal motions and provides fruitful insights to the dynamic behaviors of a system.

  19. Coupling Dynamics Interlip Coordination in Lower Lip Load Compensation

    ERIC Educational Resources Information Center

    van Lieshout, Pascal; Neufeld, Chris

    2014-01-01

    Purpose: To study the effects of lower lip loading on lower and upper lip movements and their coordination to test predictions on coupling dynamics derived from studies in limb control. Method: Movement data were acquired using electromagnetic midsagittal articulography under 4 conditions: (a) without restrictions, serving as a baseline; (b) with…

  20. The Teaching of Polar Coordinates with Dynamic Mathematics Software

    ERIC Educational Resources Information Center

    Zengin, Yilmaz; Tatar, Enver

    2015-01-01

    The purpose of this study was to determine the effects of dynamic mathematics software on the achievement of pre-service mathematics teachers in the topic of polar coordinates and to solicit their opinions about computer-assisted instruction. The study was conducted for 11 weeks with 33 pre-service teachers in the Department of Mathematics…

  1. Functional coordination of muscles underlying changes in behavioural dynamics

    PubMed Central

    Vernooij, Carlijn A.; Rao, Guillaume; Perdikis, Dionysios; Huys, Raoul; Jirsa, Viktor K.; Temprado, Jean-Jacques

    2016-01-01

    The dynamical systems approach addresses Bernstein’s degrees of freedom problem by assuming that the neuro-musculo-skeletal system transiently assembles and dismantles its components into functional units (or synergies) to meet task demands. Strikingly, little is known from a dynamical point of view about the functioning of the muscular sub-system in this process. To investigate the interaction between the dynamical organisation at muscular and behavioural levels, we searched for specific signatures of a phase transition in muscular coordination when a transition is displayed at the behavioural level. Our results provide evidence that, during Fitts’ task when behaviour switches to a different dynamical regime, muscular activation displays typical signatures of a phase transition; a reorganisation in muscular coordination patterns accompanied by a peak in the variability of muscle activation. This suggests that consistent changes occur in coordination processes across the different levels of description (i.e., behaviour and muscles). Specifically, in Fitts’ task, target size acts as a control parameter that induces a destabilisation and a reorganisation of coordination patterns at different levels of the neuro-musculo-skeletal system. PMID:27282349

  2. Automatic ball bar for a coordinate measuring machine

    DOEpatents

    Jostlein, H.

    1997-07-15

    An automatic ball bar for a coordinate measuring machine determines the accuracy of a coordinate measuring machine having at least one servo drive. The apparatus comprises a first and second gauge ball connected by a telescoping rigid member. The rigid member includes a switch such that inward radial movement of the second gauge ball relative to the first gauge ball causes activation of the switch. The first gauge ball is secured in a first magnetic socket assembly in order to maintain the first gauge ball at a fixed location with respect to the coordinate measuring machine. A second magnetic socket assembly secures the second gauge ball to the arm or probe holder of the coordinate measuring machine. The second gauge ball is then directed by the coordinate measuring machine to move radially inward from a point just beyond the length of the ball bar until the switch is activated. Upon switch activation, the position of the coordinate measuring machine is determined and compared to known ball bar length such that the accuracy of the coordinate measuring machine can be determined. 5 figs.

  3. Automatic ball bar for a coordinate measuring machine

    DOEpatents

    Jostlein, Hans

    1997-01-01

    An automatic ball bar for a coordinate measuring machine determines the accuracy of a coordinate measuring machine having at least one servo drive. The apparatus comprises a first and second gauge ball connected by a telescoping rigid member. The rigid member includes a switch such that inward radial movement of the second gauge ball relative to the first gauge ball causes activation of the switch. The first gauge ball is secured in a first magnetic socket assembly in order to maintain the first gauge ball at a fixed location with respect to the coordinate measuring machine. A second magnetic socket assembly secures the second gauge ball to the arm or probe holder of the coordinate measuring machine. The second gauge ball is then directed by the coordinate measuring machine to move radially inward from a point just beyond the length of the ball bar until the switch is activated. Upon switch activation, the position of the coordinate measuring machine is determined and compared to known ball bar length such that the accuracy of the coordinate measuring machine can be determined.

  4. Rowing Crew Coordination Dynamics at Increasing Stroke Rates

    PubMed Central

    2015-01-01

    In rowing, perfect synchronisation is important for optimal performance of a crew. Remarkably, a recent study on ergometers demonstrated that antiphase crew coordination might be mechanically more efficient by reducing the power lost to within-cycle velocity fluctuations of the boat. However, coupled oscillator dynamics predict the stability of the coordination to decrease with increasing stroke rate, which in case of antiphase may eventually yield breakdowns to in-phase. Therefore, this study examined the effects of increasing stroke rate on in- and antiphase crew coordination in rowing dyads. Eleven experienced dyads rowed on two mechanically coupled ergometers on slides, which allowed the ergometer system to move back and forth as one ‘boat’. The dyads performed a ramp trial in both in- and antiphase pattern, in which stroke rates gradually increased from 30 strokes per minute (spm) to as fast as possible in steps of 2 spm. Kinematics of rowers, handles and ergometers were captured. Two dyads showed a breakdown of antiphase into in-phase coordination at the first stroke rate of the ramp trial. The other nine dyads reached between 34–42 spm in antiphase but achieved higher rates in in-phase. As expected, the coordinative accuracy in antiphase was worse than in in-phase crew coordination, while, somewhat surprisingly, the coordinative variability did not differ between the patterns. Whereas crew coordination did not substantially deteriorate with increasing stroke rate, stroke rate did affect the velocity fluctuations of the ergometers: fluctuations were clearly larger in the in-phase pattern than in the antiphase pattern, and this difference significantly increased with stroke rate. Together, these results suggest that although antiphase rowing is less stable (i.e., less resistant to perturbation), potential on-water benefits of antiphase over in-phase rowing may actually increase with stroke rate. PMID:26185987

  5. Coordinate Measuring Machine Pit Artifact Inspection Procedure

    SciTech Connect

    Montano, Joshua D.

    2012-07-31

    The goal of this document is to outline a procedure for dimensional measurement of Los Alamos National Laboratory's CMM Pit Artifact. This procedure will be used by the Manufacturing Practice's Inspection Technology Subgroup of the Interagency Manufacturing Operations Group and Joint Operations Weapon Operations Group (IMOG/JOWOG 39) round robin participants. The intent is to assess the state of industry within the Nuclear Weapons Complex for measurements made on this type of part and find which current measurement strategies and techniques produce the best results.

  6. Toward a Complementary Neuroscience: Metastable Coordination Dynamics of the Brain

    NASA Astrophysics Data System (ADS)

    Kelso, J. A. Scott; Tognoli, Emmanuelle

    Metastability has been proposed as a new principle of behavioral and brain function and may point the way to a truly complementary neuroscience. From elementary coordination dynamics we show explicitly that metastability is a result of a symmetry-breaking caused by the subtle interplay of two forces: the tendency of the components to couple together and the tendency of the components to express their intrinsic independent behavior. The metastable regime reconciles the well-known tendencies of specialized brain regions to express their autonomy (segregation) and the tendencies for those regions to work together as a synergy (integration). Integration ~ segregation is just one of the complementary pairs (denoted by the tilde [~] symbol) to emerge from the science of coordination dynamics. We discuss metastability in the brain by describing the favorable conditions existing for its emergence and by deriving some predictions for its empirical characterization in neurophysiological recordings.

  7. Advanced techniques for constrained internal coordinate molecular dynamics.

    PubMed

    Wagner, Jeffrey R; Balaraman, Gouthaman S; Niesen, Michiel J M; Larsen, Adrien B; Jain, Abhinandan; Vaidehi, Nagarajan

    2013-04-30

    Internal coordinate molecular dynamics (ICMD) methods provide a more natural description of a protein by using bond, angle, and torsional coordinates instead of a Cartesian coordinate representation. Freezing high-frequency bonds and angles in the ICMD model gives rise to constrained ICMD (CICMD) models. There are several theoretical aspects that need to be developed to make the CICMD method robust and widely usable. In this article, we have designed a new framework for (1) initializing velocities for nonindependent CICMD coordinates, (2) efficient computation of center of mass velocity during CICMD simulations, (3) using advanced integrators such as Runge-Kutta, Lobatto, and adaptive CVODE for CICMD simulations, and (4) cancelling out the "flying ice cube effect" that sometimes arises in Nosé-Hoover dynamics. The Generalized Newton-Euler Inverse Mass Operator (GNEIMO) method is an implementation of a CICMD method that we have developed to study protein dynamics. GNEIMO allows for a hierarchy of coarse-grained simulation models based on the ability to rigidly constrain any group of atoms. In this article, we perform tests on the Lobatto and Runge-Kutta integrators to determine optimal simulation parameters. We also implement an adaptive coarse-graining tool using the GNEIMO Python interface. This tool enables the secondary structure-guided "freezing and thawing" of degrees of freedom in the molecule on the fly during molecular dynamics simulations and is shown to fold four proteins to their native topologies. With these advancements, we envision the use of the GNEIMO method in protein structure prediction, structure refinement, and in studying domain motion.

  8. Coordination of Cellular Dynamics Contributes to Tooth Epithelium Deformations

    PubMed Central

    Morita, Ritsuko; Kihira, Miho; Nakatsu, Yousuke; Nomoto, Yohei; Ogawa, Miho; Ohashi, Kazumasa; Mizuno, Kensaku; Tachikawa, Tetsuhiko; Ishimoto, Yukitaka; Morishita, Yoshihiro; Tsuji, Takashi

    2016-01-01

    The morphologies of ectodermal organs are shaped by appropriate combinations of several deformation modes, such as invagination and anisotropic tissue elongation. However, how multicellular dynamics are coordinated during deformation processes remains to be elucidated. Here, we developed a four-dimensional (4D) analysis system for tracking cell movement and division at a single-cell resolution in developing tooth epithelium. The expression patterns of a Fucci probe clarified the region- and stage-specific cell cycle patterns within the tooth germ, which were in good agreement with the pattern of the volume growth rate estimated from tissue-level deformation analysis. Cellular motility was higher in the regions with higher growth rates, while the mitotic orientation was significantly biased along the direction of tissue elongation in the epithelium. Further, these spatio-temporal patterns of cellular dynamics and tissue-level deformation were highly correlated with that of the activity of cofilin, which is an actin depolymerization factor, suggesting that the coordination of cellular dynamics via actin remodeling plays an important role in tooth epithelial morphogenesis. Our system enhances the understanding of how cellular behaviors are coordinated during ectodermal organogenesis, which cannot be observed from histological analyses. PMID:27588418

  9. Advanced Techniques for Constrained Internal Coordinate Molecular Dynamics

    PubMed Central

    Wagner, Jeffrey R.; Balaraman, Gouthaman S.; Niesen, Michiel J. M.; Larsen, Adrien B.; Jain, Abhinandan; Vaidehi, Nagarajan

    2013-01-01

    Internal coordinate molecular dynamics (ICMD) methods provide a more natural description of a protein by using bond, angle and torsional coordinates instead of a Cartesian coordinate representation. Freezing high frequency bonds and angles in the ICMD model gives rise to constrained ICMD (CICMD) models. There are several theoretical aspects that need to be developed in order to make the CICMD method robust and widely usable. In this paper we have designed a new framework for 1) initializing velocities for non-independent CICMD coordinates, 2) efficient computation of center of mass velocity during CICMD simulations, 3) using advanced integrators such as Runge-Kutta, Lobatto and adaptive CVODE for CICMD simulations, and 4) cancelling out the “flying ice cube effect” that sometimes arises in Nosé-Hoover dynamics. The Generalized Newton-Euler Inverse Mass Operator (GNEIMO) method is an implementation of a CICMD method that we have developed to study protein dynamics. GNEIMO allows for a hierarchy of coarse-grained simulation models based on the ability to rigidly constrain any group of atoms. In this paper, we perform tests on the Lobatto and Runge-Kutta integrators to determine optimal simulation parameters. We also implement an adaptive coarse graining tool using the GNEIMO Python interface. This tool enables the secondary structure-guided “freezing and thawing” of degrees of freedom in the molecule on the fly during MD simulations, and is shown to fold four proteins to their native topologies. With these advancements we envision the use of the GNEIMO method in protein structure prediction, structure refinement, and in studying domain motion. PMID:23345138

  10. Dynamic structural transformations of coordination supramolecular systems upon exogenous stimulation.

    PubMed

    Li, Cheng-Peng; Chen, Jing; Liu, Chun-Sen; Du, Miao

    2015-02-18

    Reactions in the solid state, especially single-crystal-to-single-crystal (SC-SC) transformations, provide an appealing pathway to obtain target crystalline materials with modified properties via a solvent-free green chemistry approach. This feature article focuses on the progress to date in the context of coordination supramolecular systems (CSSs), especially coordination polymers (CPs) or metal-organic frameworks (MOFs), which show interesting dynamic natures upon exposure to various exogenous stimuli, including concentration, temperature, light and mechanical force, as well as their synergic effect. In essence, dynamic CSSs normally possess crucial crystalline-reactive characteristics: (i) metal ions or clusters with unstable or metastable electronic configurations and coordination geometries; (ii) organic ligands bearing physicochemically active functional groups for subsequent reactions; (iii) polymeric networks of high flexibility for structural bending, rotation, swelling, or shrinking; (iv) guest moieties to be freely exchanged or eliminated by varying the environmental conditions. The significant changes in catalytic, sorption, magnetic, or luminescent properties accompanied by the structural transformations will also be discussed, which reveal the proof-of-concept thereof in designing new functional crystalline materials.

  11. Measuring a hidden coordinate: Rate-exchange kinetics from 3D correlation functions.

    PubMed

    Berg, Mark A; Darvin, Jason R

    2016-08-07

    Nonexponential kinetics imply the existence of at least one slow variable other than the observable, that is, the system has a "hidden" coordinate. We develop a simple, but general, model that allows multidimensional correlation functions to be calculated for these systems. Homogeneous and heterogeneous mechanisms are both included, and slow exchange of the rates is allowed. This model shows that 2D and 3D correlation functions of the observable measure the distribution and kinetics of the hidden coordinate controlling the rate exchange. Both the mean exchange time and the shape of the exchange relaxation are measurable. However, complications arise because higher correlation functions are sums of multiple "pathways," each of which measures different dynamics. Only one 3D pathway involves exchange dynamics. Care must be used to extract exchange dynamics without contamination from other processes.

  12. Unified Selenocentric Reference Coordinates Net in the Dynamic System

    NASA Astrophysics Data System (ADS)

    Nefedyev, Yuri; Petrova, Natalia; Varaksina, Natalia

    In this report the task of the making selenocentric inertial reference net is solved. The purpose is making summary reference net by expansion KSC-1162 selenodetic system using 12 cosmic and ground selenodesic catalogues. The prospective analysis of this net was performed. These selenocentric reference catalogue covers full visible and a part of far lunar sides. Modern cosmic technologies need the accurate coordinate - temporal support including reference frame realization, inertial and dynamic system orientation and studying dynamic and geometry celestial bodies. That refers to dynamic and geometric selenocentric lunar parameters. The catalogue based on mission “Apollo” and reference nets of the west lunar hemisphere made by missions “Zond 5”, ”Zond 8” cover small part of the Moon surface. Three ALSEP stations were used to transform “Apollo” topographic coordinates. Transformation mean-square errors are less than 80 meters and measurement’s errors are about 60 meters. On this account positions inaccuracy near and between ALSEP stations are less 150 meters. The offset from place of the location ALSEP enlarges the supposed mistake is more than 300 m and this is a major part of the lunar surface. In solving the problem of high-precision condensation and expansion of fundamental selenocentric net KSC-1162 on the visible side of the Moon and lunar far side were obtained following new results: a) the analysis and investigation of the accuracy of basic net contained in ULCN were carried out; b) the decryption of common objects for coordinate systems which are being explored was executed; c) the extension of the mathematical content package TSC was carried out; d) the development of TSC as an expert system of universal transformation planet's coordinates was carried out; e) the possibility of applying the ARM-approach to the problem TC on common objects, which allows to find optimal parameter estimation and model structure of TC was confirmed; f) the

  13. Measurement error analysis of three dimensional coordinates of tomatoes acquired using the binocular stereo vision

    NASA Astrophysics Data System (ADS)

    Xiang, Rong

    2014-09-01

    This study analyzes the measurement errors of three dimensional coordinates of binocular stereo vision for tomatoes based on three stereo matching methods, centroid-based matching, area-based matching, and combination matching to improve the localization accuracy of the binocular stereo vision system of tomato harvesting robots. Centroid-based matching was realized through the matching of the feature points of centroids of tomato regions. Area-based matching was realized based on the gray similarity between two neighborhoods of two pixels to be matched in stereo images. Combination matching was realized using the rough disparity acquired through centroid-based matching as the center of the dynamic disparity range which was used in area-based matching. After stereo matching, three dimensional coordinates of tomatoes were acquired using the triangle range finding principle. Test results based on 225 stereo images captured at the distances from 300 to 1000 mm of 3 tomatoes showed that the measurement errors of x coordinates were small, and can meet the need of harvesting robots. However, the measurement biases of y coordinates and depth values were large, and the measurement variation of depth values was also large. Therefore, the measurement biases of y coordinates and depth values, and the measurement variation of depth values should be corrected in the future researches.

  14. Projectile Two-dimensional Coordinate Measurement Method Based on Optical Fiber Coding Fire and its Coordinate Distribution Probability

    NASA Astrophysics Data System (ADS)

    Li, Hanshan; Lei, Zhiyong

    2013-01-01

    To improve projectile coordinate measurement precision in fire measurement system, this paper introduces the optical fiber coding fire measurement method and principle, sets up their measurement model, and analyzes coordinate errors by using the differential method. To study the projectile coordinate position distribution, using the mathematical statistics hypothesis method to analyze their distributing law, firing dispersion and probability of projectile shooting the object center were put under study. The results show that exponential distribution testing is relatively reasonable to ensure projectile position distribution on the given significance level. Through experimentation and calculation, the optical fiber coding fire measurement method is scientific and feasible, which can gain accurate projectile coordinate position.

  15. Articulated Arm Coordinate Measuring Machine Calibration by Laser Tracker Multilateration

    PubMed Central

    Majarena, Ana C.; Brau, Agustín; Velázquez, Jesús

    2014-01-01

    A new procedure for the calibration of an articulated arm coordinate measuring machine (AACMM) is presented in this paper. First, a self-calibration algorithm of four laser trackers (LTs) is developed. The spatial localization of a retroreflector target, placed in different positions within the workspace, is determined by means of a geometric multilateration system constructed from the four LTs. Next, a nonlinear optimization algorithm for the identification procedure of the AACMM is explained. An objective function based on Euclidean distances and standard deviations is developed. This function is obtained from the captured nominal data (given by the LTs used as a gauge instrument) and the data obtained by the AACMM and compares the measured and calculated coordinates of the target to obtain the identified model parameters that minimize this difference. Finally, results show that the procedure presented, using the measurements of the LTs as a gauge instrument, is very effective by improving the AACMM precision. PMID:24688418

  16. Coordinate measuring machine test standard apparatus and method

    DOEpatents

    Bieg, Lothar F.

    1994-08-30

    A coordinate measuring machine test standard apparatus and method which iudes a rotary spindle having an upper phase plate and an axis of rotation, a kinematic ball mount attached to the phase plate concentric with the axis of rotation of the phase plate, a groove mounted at the circumference of the phase plate, and an arm assembly which rests in the groove. The arm assembly has a small sphere at one end and a large sphere at the other end. The small sphere may be a coordinate measuring machine probe tip and may have variable diameters. The large sphere is secured in the kinematic ball mount and the arm is held in the groove. The kinematic ball mount includes at least three mounting spheres and the groove is an angular locating groove including at least two locking spheres. The arm may have a hollow inner core and an outer layer. The rotary spindle may be a ratio reducer. The device is used to evaluate the measuring performance of a coordinate measuring machine for periodic recertification, including 2 and 3 dimensional accuracy, squareness, straightness, and angular accuracy.

  17. Coordinate measuring machine test standard apparatus and method

    DOEpatents

    Bieg, L.F.

    1994-08-30

    A coordinate measuring machine test standard apparatus and method are disclosed which includes a rotary spindle having an upper phase plate and an axis of rotation, a kinematic ball mount attached to the phase plate concentric with the axis of rotation of the phase plate, a groove mounted at the circumference of the phase plate, and an arm assembly which rests in the groove. The arm assembly has a small sphere at one end and a large sphere at the other end. The small sphere may be a coordinate measuring machine probe tip and may have variable diameters. The large sphere is secured in the kinematic ball mount and the arm is held in the groove. The kinematic ball mount includes at least three mounting spheres and the groove is an angular locating groove including at least two locking spheres. The arm may have a hollow inner core and an outer layer. The rotary spindle may be a ratio reducer. The device is used to evaluate the measuring performance of a coordinate measuring machine for periodic recertification, including 2 and 3 dimensional accuracy, squareness, straightness, and angular accuracy. 5 figs.

  18. NMR with generalized dynamics of spin and spatial coordinates

    SciTech Connect

    Lee, Chang Jae

    1987-11-01

    This work is concerned with theoretical and experimental aspects of the generalized dynamics of nuclear spin and spatial coordinates under magnetic-field pulses and mechanical motions. The main text begins with an introduction to the concept of ''fictitious'' interactions. A systematic method for constructing fictitious spin-1/2 operators is given. The interaction of spins with a quantized-field is described. The concept of the fictitious interactions under the irradiation of multiple pulses is utilized to design sequences for selectively averaging linear and bilinear operators. Relations between the low-field sequences and high-field iterative schemes are clarified. These relations and the transformation properties of the spin operators are exploited to develop schemes for heteronuclear decoupling of multi-level systems. The resulting schemes are evaluated for heteronuclear decoupling of a dilute spin-1/2 from a spin-1 in liquid crystal samples and from a homonuclear spin-1/2 pair in liquids. A relation between the spin and the spatial variables is discussed. The transformation properties of the spin operators are applied to spatial coordinates and utilized to develop methods for removing the orientational dependence responsible for line broadening in a powder sample. Elimination of the second order quadrupole effects, as well as the first order anisotropies is discussed. It is shown that various sources of line broadening can effectively be eliminated by spinning and/or hopping the sample about judiciously chosen axes along with appropriate radio-frequency pulse sequences.

  19. Spatially coordinated dynamic gene transcription in living pituitary tissue.

    PubMed

    Featherstone, Karen; Hey, Kirsty; Momiji, Hiroshi; McNamara, Anne V; Patist, Amanda L; Woodburn, Joanna; Spiller, David G; Christian, Helen C; McNeilly, Alan S; Mullins, John J; Finkenstädt, Bärbel F; Rand, David A; White, Michael R H; Davis, Julian R E

    2016-02-01

    Transcription at individual genes in single cells is often pulsatile and stochastic. A key question emerges regarding how this behaviour contributes to tissue phenotype, but it has been a challenge to quantitatively analyse this in living cells over time, as opposed to studying snap-shots of gene expression state. We have used imaging of reporter gene expression to track transcription in living pituitary tissue. We integrated live-cell imaging data with statistical modelling for quantitative real-time estimation of the timing of switching between transcriptional states across a whole tissue. Multiple levels of transcription rate were identified, indicating that gene expression is not a simple binary 'on-off' process. Immature tissue displayed shorter durations of high-expressing states than the adult. In adult pituitary tissue, direct cell contacts involving gap junctions allowed local spatial coordination of prolactin gene expression. Our findings identify how heterogeneous transcriptional dynamics of single cells may contribute to overall tissue behaviour.

  20. Coordinated scheduling for dynamic real-time systems

    NASA Technical Reports Server (NTRS)

    Natarajan, Swaminathan; Zhao, Wei

    1994-01-01

    In this project, we addressed issues in coordinated scheduling for dynamic real-time systems. In particular, we concentrated on design and implementation of a new distributed real-time system called R-Shell. The design objective of R-Shell is to provide computing support for space programs that have large, complex, fault-tolerant distributed real-time applications. In R-shell, the approach is based on the concept of scheduling agents, which reside in the application run-time environment, and are customized to provide just those resource management functions which are needed by the specific application. With this approach, we avoid the need for a sophisticated OS which provides a variety of generalized functionality, while still not burdening application programmers with heavy responsibility for resource management. In this report, we discuss the R-Shell approach, summarize the achievement of the project, and describe a preliminary prototype of R-Shell system.

  1. Coordinated Dynamic Behaviors for Multirobot Systems With Collision Avoidance.

    PubMed

    Sabattini, Lorenzo; Secchi, Cristian; Fantuzzi, Cesare

    2016-08-16

    In this paper, we propose a novel methodology for achieving complex dynamic behaviors in multirobot systems. In particular, we consider a multirobot system partitioned into two subgroups: 1) dependent and 2) independent robots. Independent robots are utilized as a control input, and their motion is controlled in such a way that the dependent robots solve a tracking problem, that is following arbitrarily defined setpoint trajectories, in a coordinated manner. The control strategy proposed in this paper explicitly addresses the collision avoidance problem, utilizing a null space-based behavioral approach: this leads to combining, in a non conflicting manner, the tracking control law with a collision avoidance strategy. The combination of these control actions allows the robots to execute their task in a safe way. Avoidance of collisions is formally proven in this paper, and the proposed methodology is validated by means of simulations and experiments on real robots.

  2. Post-Newtonian cosmological dynamics in Lagrangian coordinates

    NASA Astrophysics Data System (ADS)

    Matarrese, Sabino; Terranova, David

    1996-11-01

    We study the non-linear dynamics of self-gravitating irrotational dust in a general relativistic framework, using synchronous and comoving (i.e. Lagrangian) coordinates. All the equations are written in terms of a single tensor variable, the metric tensor of the spatial sections orthogonal to the fluid flow. This treatment allows an unambiguous expansion in inverse (even) powers of the speed of light. To lowest order, the Newtonian approximation - in Lagrangian form - is derived and written in a transparent way; the corresponding Lagrangian Newtonian metric is obtained. Post-Newtonian corrections are then derived and their physical meaning clarified. A number of results are obtained: (i) the master equation of Lagrangian Newtonian dynamics, the Raychaudhuri equation, can be interpreted as an equation for the evolution of the Lagrangian-to-Eulerian Jacobian matrix, complemented by the irrotationality constraint; (ii) the Lagrangian spatial metric reduces, in the Newtonian limit, to that of Euclidean 3-space written in time-dependent curvilinear coordinates, with non-vanishing Christoffel symbols, but vanishing spatial curvature (a particular example of it is given within the Zel'dovich approximation); (iii) a Lagrangian version of the Bernoulli equation for the evolution of the `velocity potential' is obtained. (iv) The Newtonian and post-Newtonian content of the electric and magnetic parts of the Weyl tensor is clarified. (v) At the post-Newtonian level, an exact and general formula is derived for gravitational-wave emission from non-linear cosmological perturbations; (vi) a straightforward application to the anisotropic collapse of homogeneous ellipsoids shows that the ratio of these postNewtonian terms to the Newtonian ones tends to diverge at least like the mass density. (vii) It is argued that a stochastic gravitational wave background is produced by non-linear cosmic structures, with present-day closure density Ωgw ˜10-5-10-6 on 1-10 Mpc scales.

  3. Project Vesta: A Laboratory Exercise on the Measurement of Celestial Coordinates

    ERIC Educational Resources Information Center

    Laird, David E.

    1974-01-01

    Described is an activity that was developed to measure celestial coordinates. Pictures were taken of the asteroid Vesta, coordinates for reference stars determined, and then celestial coordinates of Vesta were determined with assistance of a computer. (RH)

  4. Vertical coordinates measurement based on intersection laser screens

    NASA Astrophysics Data System (ADS)

    Zhang, Bin; Wang, Zhaoba; Zhao, Donge; Liu, Ji

    2015-10-01

    In order to solve the weakness of traditional vertical target coordinate measurement, such as complex structure, inconvenient debugging and difficult to form a large area target, a method based on intersection laser screens was proposed. The effective area of was constituted by the intersection of two fan-shaped laser screens. Photodiode (PD) array was used to measure the intensity of laser light. When the projectile passes through the laser screens, the corresponding PDs receive signal. After signal processing and adaptive threshold comparator circuit processing, the signal is transmitted to PC to calculate the projectile target coordinate. The calculation method of feature point and the calculation process of coordinate were described in detail. Error distribution in effective area was analyzed. Experiment was carried out by using simulating projectile and the principle prototype whose effective target area is 1m×1m. The result shows that the precision of location measurement is up to 2mm. The method has the advantages of simple structure, convenient debugging. It is easy to construct a larger area target, and the maximum effective area can reach to 6m×6m.

  5. Statistical process control (SPC) for coordinate measurement machines

    SciTech Connect

    Escher, R.N.

    2000-01-04

    The application of process capability analysis, using designed experiments, and gage capability studies as they apply to coordinate measurement machine (CMM) uncertainty analysis and control will be demonstrated. The use of control standards in designed experiments, and the use of range charts and moving range charts to separate measurement error into it's discrete components will be discussed. The method used to monitor and analyze the components of repeatability and reproducibility will be presented with specific emphasis on how to use control charts to determine and monitor CMM performance and capability, and stay within your uncertainty assumptions.

  6. Dimensional coordinate measurements: application in characterizing cervical spine motion

    NASA Astrophysics Data System (ADS)

    Zheng, Weilong; Li, Linan; Wang, Shibin; Wang, Zhiyong; Shi, Nianke; Xue, Yuan

    2014-06-01

    Cervical spine as a complicated part in the human body, the form of its movement is diverse. The movements of the segments of vertebrae are three-dimensional, and it is reflected in the changes of the angle between two joint and the displacement in different directions. Under normal conditions, cervical can flex, extend, lateral flex and rotate. For there is no relative motion between measuring marks fixed on one segment of cervical vertebra, the cervical vertebrae with three marked points can be seen as a body. Body's motion in space can be decomposed into translational movement and rotational movement around a base point .This study concerns the calculation of dimensional coordinate of the marked points pasted to the human body's cervical spine by an optical method. Afterward, these measures will allow the calculation of motion parameters for every spine segment. For this study, we choose a three-dimensional measurement method based on binocular stereo vision. The object with marked points is placed in front of the CCD camera. Through each shot, we will get there two parallax images taken from different cameras. According to the principle of binocular vision we can be realized three-dimensional measurements. Cameras are erected parallelly. This paper describes the layout of experimental system and a mathematical model to get the coordinates.

  7. Measuring Family Dynamics.

    ERIC Educational Resources Information Center

    Kunce, Joseph T.; Priesmeyer, Marydeth L.

    1985-01-01

    Investigated dimensions of family dynamics via test construction and cross validation, with a developmental sample (N=93) and a validity generalization sample (N=65). Developed two scales that correlated significantly with perceptions of family stability and quality in the developmental and validity generalization samples. (BH)

  8. Decision-making ability of Physarum polycephalum enhanced by its coordinated spatiotemporal oscillatory dynamics.

    PubMed

    Iwayama, Koji; Zhu, Liping; Hirata, Yoshito; Aono, Masashi; Hara, Masahiko; Aihara, Kazuyuki

    2016-04-12

    An amoeboid unicellular organism, a plasmodium of the true slime mold Physarum polycephalum, exhibits complex spatiotemporal oscillatory dynamics and sophisticated information processing capabilities while deforming its amorphous body. We previously devised an 'amoeba-based computer (ABC),' that implemented optical feedback control to lead this amoeboid organism to search for a solution to the traveling salesman problem (TSP). In the ABC, the shortest TSP route (the optimal solution) is represented by the shape of the organism in which the body area (nutrient absorption) is maximized while the risk of being exposed to aversive light stimuli is minimized. The shortness of the TSP route found by ABC, therefore, serves as a quantitative measure of the optimality of the decision made by the organism. However, it remains unclear how the decision-making ability of the organism originates from the oscillatory dynamics of the organism. We investigated the number of coexisting traveling waves in the spatiotemporal patterns of the oscillatory dynamics of the organism. We show that a shorter TSP route can be found when the organism exhibits a lower number of traveling waves. The results imply that the oscillatory dynamics are highly coordinated throughout the global body. Based on the results, we discuss the fact that the decision-making ability of the organism can be enhanced not by uncorrelated random fluctuations, but by its highly coordinated oscillatory dynamics.

  9. Spatially coordinated dynamic gene transcription in living pituitary tissue

    PubMed Central

    Featherstone, Karen; Hey, Kirsty; Momiji, Hiroshi; McNamara, Anne V; Patist, Amanda L; Woodburn, Joanna; Spiller, David G; Christian, Helen C; McNeilly, Alan S; Mullins, John J; Finkenstädt, Bärbel F; Rand, David A; White, Michael RH; Davis, Julian RE

    2016-01-01

    Transcription at individual genes in single cells is often pulsatile and stochastic. A key question emerges regarding how this behaviour contributes to tissue phenotype, but it has been a challenge to quantitatively analyse this in living cells over time, as opposed to studying snap-shots of gene expression state. We have used imaging of reporter gene expression to track transcription in living pituitary tissue. We integrated live-cell imaging data with statistical modelling for quantitative real-time estimation of the timing of switching between transcriptional states across a whole tissue. Multiple levels of transcription rate were identified, indicating that gene expression is not a simple binary ‘on-off’ process. Immature tissue displayed shorter durations of high-expressing states than the adult. In adult pituitary tissue, direct cell contacts involving gap junctions allowed local spatial coordination of prolactin gene expression. Our findings identify how heterogeneous transcriptional dynamics of single cells may contribute to overall tissue behaviour. DOI: http://dx.doi.org/10.7554/eLife.08494.001 PMID:26828110

  10. Dynamic modulation of illusory and physical target size on separate and coordinated eye and hand movements

    PubMed Central

    Gamble, Christine M.; Song, Joo-Hyun

    2017-01-01

    In everyday behavior, two of the most common visually guided actions—eye and hand movements—can be performed independently, but are often synergistically coupled. In this study, we examine whether the same visual representation is used for different stages of saccades and pointing, namely movement preparation and execution, and whether this usage is consistent between independent and naturalistic coordinated eye and hand movements. To address these questions, we used the Ponzo illusion to dissociate the perceived and physical sizes of visual targets and measured the effects on movement preparation and execution for independent and coordinated saccades and pointing. During independent movements, we demonstrated that both physically and perceptually larger targets produced faster preparation for both effectors. Furthermore, participants who showed a greater influence of the illusion on saccade preparation also showed a greater influence on pointing preparation, suggesting that a shared mechanism involved in preparation across effectors is influenced by illusions. However, only physical but not perceptual target sizes influenced saccade and pointing execution. When pointing was coordinated with saccades, we observed different dynamics: pointing no longer showed modulation from illusory size, while saccades showed illusion modulation for both preparation and execution. Interestingly, in independent and coordinated movements, the illusion modulated saccade preparation more than pointing preparation, with this effect more pronounced during coordination. These results suggest a shared mechanism, dominated by the eyes, may underlie visually guided action preparation across effectors. Furthermore, the influence of illusions on action may operate within such a mechanism, leading to dynamic interactions between action modalities based on task demands. PMID:28362898

  11. Extracting numeric measurements and temporal coordinates from Japanese radiological reports

    NASA Astrophysics Data System (ADS)

    Imai, Takeshi; Onogi, Yuzo

    2004-04-01

    Medical records are written mainly, in natural language. The focus of this study is narrative radiological reports written in natural Japanese. These reports cannot be used for advanced retrieval, data mining, and so on, unless they are stored, using a structured format such as DICOM-SR. The goal is to structure narrative reports progressively, using natural language processing (NLP). Structure has many different levels, for example, DICOM-SR has three established levels -- basic text, enhanced and comprehensive. At the enhanced level, it is necessary to use numerical measurements and spatial & temporal coordinates. In this study, the wording used in the reports was first standardized, dictionaries were organized, and morphological analysis performed. Next, numerical measurements and temporal coordinates were extracted, and the objects to which they referred, analyzed. 10,000 CT and MR reports were separated into 82,122 sentences, and 34,269 of the 36,444 numerical descriptions were tagged. Periods, slashes, hyphens, and parentheses are ambiguously used in the description of enumerated lists, dates, image numbers, and anatomical names, as well as at the end of sentences; to resolve this ambiguity, descriptions were processed, according to the order -- date, size, unit, enumerated list, and abbreviation -- then, the tagged reports were separated into sentences.

  12. Control systems improvements in a precision coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Douglass, S. S.; Babelay, E. F., Jr.; Igou, R. E.; Woodard, L. M.; Green, W. L.

    1981-09-01

    A conventional, manually driven Moore No. 3 coordinate measuring machine at the Oak Ridge Y-12 Plant is being upgraded to provide a continuous-path numerical control capability and simultaneously serve as a vehicle for testing new machine slide-control concepts. Besides new lead screw drive motors, an NC machine control unit, and a closed-loop servo system, the machine has also been equipped with vibration isolation, air-bearing slideways, and laser interferometric position feedback. The present conventional slide servo system will be replaced with a digital servo system wherein various feedback and compensation techniques can be realized through the use of a high speed, dedicated digital processor. The improvements to data are described with emphasis on identification and compensation of the slide control systems.

  13. Mass properties measurement system dynamics

    NASA Technical Reports Server (NTRS)

    Doty, Keith L.

    1993-01-01

    The MPMS mechanism possess two revolute degrees-of-freedom and allows the user to measure the mass, center of gravity, and the inertia tensor of an unknown mass. The dynamics of the Mass Properties Measurement System (MPMS) from the Lagrangian approach to illustrate the dependency of the motion on the unknown parameters.

  14. Mutual and asynchronous anticipation and action in sports as globally competitive and locally coordinative dynamics

    PubMed Central

    Fujii, Keisuke; Isaka, Tadao; Kouzaki, Motoki; Yamamoto, Yuji

    2015-01-01

    Humans interact by changing their actions, perceiving other’s actions and executing solutions in conflicting situations. Using oscillator models, nonlinear dynamics have been considered for describing these complex human movements as an emergence of self-organisation. However, these frameworks cannot explain the hierarchical structures of complex behaviours between conflicting inter-agent and adapting intra-agent systems, especially in sport competitions wherein mutually quick decision making and execution are required. Here we adopt a hybrid multiscale approach to model an attack-and-defend game during which both players predict the opponent’s movement and move with a delay. From both simulated and measured data, one synchronous outcome between two-agent (i.e. successful defence) can be described as one attractor. In contrast, the other coordination-breaking outcome (i.e. successful attack) cannot be explained using gradient dynamics because the asymmetric interaction cannot always assume a conserved physical quantity. Instead, we provide the asymmetric and asynchronous hierarchical dynamical models to discuss two-agent competition. Our framework suggests that possessing information about an opponent and oneself in local-coordinative and global-competitive scale enables us to gain a deeper understanding of sports competitions. We anticipate developments in the scientific fields of complex movement adapting to such uncontrolled environments. PMID:26538452

  15. Mutual and asynchronous anticipation and action in sports as globally competitive and locally coordinative dynamics

    NASA Astrophysics Data System (ADS)

    Fujii, Keisuke; Isaka, Tadao; Kouzaki, Motoki; Yamamoto, Yuji

    2015-11-01

    Humans interact by changing their actions, perceiving other’s actions and executing solutions in conflicting situations. Using oscillator models, nonlinear dynamics have been considered for describing these complex human movements as an emergence of self-organisation. However, these frameworks cannot explain the hierarchical structures of complex behaviours between conflicting inter-agent and adapting intra-agent systems, especially in sport competitions wherein mutually quick decision making and execution are required. Here we adopt a hybrid multiscale approach to model an attack-and-defend game during which both players predict the opponent’s movement and move with a delay. From both simulated and measured data, one synchronous outcome between two-agent (i.e. successful defence) can be described as one attractor. In contrast, the other coordination-breaking outcome (i.e. successful attack) cannot be explained using gradient dynamics because the asymmetric interaction cannot always assume a conserved physical quantity. Instead, we provide the asymmetric and asynchronous hierarchical dynamical models to discuss two-agent competition. Our framework suggests that possessing information about an opponent and oneself in local-coordinative and global-competitive scale enables us to gain a deeper understanding of sports competitions. We anticipate developments in the scientific fields of complex movement adapting to such uncontrolled environments.

  16. Tortoise Coordinate Transformation on Apparent Horizon of a Dynamical Black Hole

    NASA Astrophysics Data System (ADS)

    Liu, Xianming; Zhao, Zheng; Liu, Wenbiao

    Thinking of Hawking radiation calculation from a Schwarzschild black hole using Damour-Ruffini method, some key requirements of the tortoise coordinate transformation are pointed out. Extending these requirements to a dynamical black hole, a dynamical tortoise coordinate transformation is proposed. Under this new dynamical tortoise coordinate transformation, Hawking radiation from a Vaidya black hole can be got successfully using Damour-Ruffini method. Moreover, we also find that the radiation should be regarded as originating from the apparent horizon rather than the event horizon at least from the viewpoint of the first law of thermodynamics.

  17. Optimal Sampling of a Reaction Coordinate in Molecular Dynamics

    NASA Technical Reports Server (NTRS)

    Pohorille, Andrew

    2005-01-01

    Estimating how free energy changes with the state of a system is a central goal in applications of statistical mechanics to problems of chemical or biological interest. From these free energy changes it is possible, for example, to establish which states of the system are stable, what are their probabilities and how the equilibria between these states are influenced by external conditions. Free energies are also of great utility in determining kinetics of transitions between different states. A variety of methods have been developed to compute free energies of condensed phase systems. Here, I will focus on one class of methods - those that allow for calculating free energy changes along one or several generalized coordinates in the system, often called reaction coordinates or order parameters . Considering that in almost all cases of practical interest a significant computational effort is required to determine free energy changes along such coordinates it is hardly surprising that efficiencies of different methods are of great concern. In most cases, the main difficulty is associated with its shape along the reaction coordinate. If the free energy changes markedly along this coordinate Boltzmann sampling of its different values becomes highly non-uniform. This, in turn, may have considerable, detrimental effect on the performance of many methods for calculating free energies.

  18. Molecular dynamics simulation of alkali borate glass using coordination dependent potential

    SciTech Connect

    Park, B.; Cormack, A.N.

    1997-12-31

    The structure of sodium borate glass was investigated by molecular dynamics simulation using coordination dependent potential model. The simulated alkali borate glass consists of basic units, BO{sub 3} triangle, BO{sub 4} tetrahedra and structural groups such as boroxol ring and triborate units. The coordination of boron is converted from 3 to 4 by adding alkali oxide.

  19. Coordinated weather balloon solar radiation measurements during a solar eclipse

    PubMed Central

    2016-01-01

    Solar eclipses provide a rapidly changing solar radiation environment. These changes can be studied using simple photodiode sensors, if the radiation reaching the sensors is unaffected by cloud. Transporting the sensors aloft using standard meteorological instrument packages modified to carry extra sensors, provides one promising but hitherto unexploited possibility for making solar eclipse radiation measurements. For the 20 March 2015 solar eclipse, a coordinated campaign of balloon-carried solar radiation measurements was undertaken from Reading (51.44°N, 0.94°W), Lerwick (60.15°N, 1.13°W) and Reykjavik (64.13°N, 21.90°W), straddling the path of the eclipse. The balloons reached sufficient altitude at the eclipse time for eclipse-induced variations in solar radiation and solar limb darkening to be measured above cloud. Because the sensor platforms were free to swing, techniques have been evaluated to correct the measurements for their changing orientation. In the swing-averaged technique, the mean value across a set of swings was used to approximate the radiation falling on a horizontal surface; in the swing-maximum technique, the direct beam was estimated by assuming that the maximum solar radiation during a swing occurs when the photodiode sensing surface becomes normal to the direction of the solar beam. Both approaches, essentially independent, give values that agree with theoretical expectations for the eclipse-induced radiation changes. This article is part of the themed issue ‘Atmospheric effects of solar eclipses stimulated by the 2015 UK eclipse’. PMID:27550757

  20. Coordinated weather balloon solar radiation measurements during a solar eclipse.

    PubMed

    Harrison, R G; Marlton, G J; Williams, P D; Nicoll, K A

    2016-09-28

    Solar eclipses provide a rapidly changing solar radiation environment. These changes can be studied using simple photodiode sensors, if the radiation reaching the sensors is unaffected by cloud. Transporting the sensors aloft using standard meteorological instrument packages modified to carry extra sensors, provides one promising but hitherto unexploited possibility for making solar eclipse radiation measurements. For the 20 March 2015 solar eclipse, a coordinated campaign of balloon-carried solar radiation measurements was undertaken from Reading (51.44°N, 0.94°W), Lerwick (60.15°N, 1.13°W) and Reykjavik (64.13°N, 21.90°W), straddling the path of the eclipse. The balloons reached sufficient altitude at the eclipse time for eclipse-induced variations in solar radiation and solar limb darkening to be measured above cloud. Because the sensor platforms were free to swing, techniques have been evaluated to correct the measurements for their changing orientation. In the swing-averaged technique, the mean value across a set of swings was used to approximate the radiation falling on a horizontal surface; in the swing-maximum technique, the direct beam was estimated by assuming that the maximum solar radiation during a swing occurs when the photodiode sensing surface becomes normal to the direction of the solar beam. Both approaches, essentially independent, give values that agree with theoretical expectations for the eclipse-induced radiation changes.This article is part of the themed issue 'Atmospheric effects of solar eclipses stimulated by the 2015 UK eclipse'.

  1. Efficient molecular quantum dynamics in coordinate and phase space using pruned bases.

    PubMed

    Larsson, H R; Hartke, B; Tannor, D J

    2016-11-28

    We present an efficient implementation of dynamically pruned quantum dynamics, both in coordinate space and in phase space. We combine the ideas behind the biorthogonal von Neumann basis (PvB) with the orthogonalized momentum-symmetrized Gaussians (Weylets) to create a new basis, projected Weylets, that takes the best from both methods. We benchmark pruned time-dependent dynamics using phase-space-localized PvB, projected Weylets, and coordinate-space-localized DVR bases, with real-world examples in up to six dimensions. For the examples studied, coordinate-space localization is the most important factor for efficient pruning and the pruned dynamics is much faster than the unpruned, exact dynamics. Phase-space localization is useful for more demanding dynamics where many basis functions are required. There, projected Weylets offer a more compact representation than pruned DVR bases.

  2. Measuring mitotic spindle dynamics in budding yeast

    NASA Astrophysics Data System (ADS)

    Plumb, Kemp

    In order to carry out its life cycle and produce viable progeny through cell division, a cell must successfully coordinate and execute a number of complex processes with high fidelity, in an environment dominated by thermal noise. One important example of such a process is the assembly and positioning of the mitotic spindle prior to chromosome segregation. The mitotic spindle is a modular structure composed of two spindle pole bodies, separated in space and spanned by filamentous proteins called microtubules, along which the genetic material of the cell is held. The spindle is responsible for alignment and subsequent segregation of chromosomes into two equal parts; proper spindle positioning and timing ensure that genetic material is appropriately divided amongst mother and daughter cells. In this thesis, I describe fluorescence confocal microscopy and automated image analysis algorithms, which I have used to observe and analyze the real space dynamics of the mitotic spindle in budding yeast. The software can locate structures in three spatial dimensions and track their movement in time. By selecting fluorescent proteins which specifically label the spindle poles and cell periphery, mitotic spindle dynamics have been measured in a coordinate system relevant to the cell division. I describe how I have characterised the accuracy and precision of the algorithms by simulating fluorescence data for both spindle poles and the budding yeast cell surface. In this thesis I also describe the construction of a microfluidic apparatus that allows for the measurement of long time-scale dynamics of individual cells and the development of a cell population. The tools developed in this thesis work will facilitate in-depth quantitative analysis of the non-equilibrium processes in living cells.

  3. Bio-Inspired Metal-Coordination Dynamics: A Unique Tool for Engineering Soft Matter Mechanics

    NASA Astrophysics Data System (ADS)

    Holten-Andersen, Niels

    Growing evidence supports a critical role of metal-coordination in soft biological material properties such as self-healing, underwater adhesion and autonomous wound plugging. Using bio-inspired metal-binding polymers, initial efforts to mimic these properties with metal-coordination crosslinked polymer materials have shown promise. In addition, with polymer network mechanics strongly coupled to coordinate crosslink dynamics material properties can be easily tuned from visco-elastic fluids to solids. Given their exploitation in desirable material applications in Nature, bio-inspired metal-coordinate complex crosslinking provides an opportunity to further advance synthetic polymer materials design. Early lessons from this pursuit are presented.

  4. Computation of free energy differences through nonequilibrium stochastic dynamics: The reaction coordinate case

    SciTech Connect

    Lelievre, Tony . E-mail: lelievre@cermics.enpc.fr; Rousset, Mathias . E-mail: rousset@cermics.enpc.fr; Stoltz, Gabriel . E-mail: stoltz@cermics.enpc.fr

    2007-03-20

    The computation of free energy differences through an exponential weighting of out-of-equilibrium paths (known as the Jarzynski equality [C. Jarzynski, Equilibrium free energy differences from nonequilibrium measurements: a master equation approach, Phys. Rev. E 56 (5) (1997) 5018-5035, C. Jarzynski, Nonequilibrium equality for free energy differences, Phys. Rev. Lett. 78 (14) (1997) 2690-2693]) is often used for transitions between states described by an external parameter in the Hamiltonian. An extension to transitions between states defined by different values of some reaction coordinate is presented here, using a projected Brownian dynamics. In contrast with other approaches (see e.g. [S. Park, F. Khalili-Araghi, E. Tajkhorshid, K. Schulten, Free energy calculation from steered molecular dynamics simulations using Jarzynski's equality, J. Chem. Phys. 119 (6) (2003) 3559-3566]), a projection is used rather than a constraining potential to let the constraints associated with the reaction coordinate evolve. It is shown how to use the Lagrange multipliers associated with these constraints to compute the work associated with a given trajectory. Appropriate discretizations are proposed. Some numerical results demonstrate the applicability of the method for the computation of free energy difference profiles.

  5. Integration of Error Compensation of Coordinate Measuring Machines into Feature Measurement: Part I-Model Development.

    PubMed

    Calvo, Roque; D'Amato, Roberto; Gómez, Emilio; Domingo, Rosario

    2016-09-29

    The development of an error compensation model for coordinate measuring machines (CMMs) and its integration into feature measurement is presented. CMMs are widespread and dependable instruments in industry and laboratories for dimensional measurement. From the tip probe sensor to the machine display, there is a complex transformation of probed point coordinates through the geometrical feature model that makes the assessment of accuracy and uncertainty measurement results difficult. Therefore, error compensation is not standardized, conversely to other simpler instruments. Detailed coordinate error compensation models are generally based on CMM as a rigid-body and it requires a detailed mapping of the CMM's behavior. In this paper a new model type of error compensation is proposed. It evaluates the error from the vectorial composition of length error by axis and its integration into the geometrical measurement model. The non-explained variability by the model is incorporated into the uncertainty budget. Model parameters are analyzed and linked to the geometrical errors and uncertainty of CMM response. Next, the outstanding measurement models of flatness, angle, and roundness are developed. The proposed models are useful for measurement improvement with easy integration into CMM signal processing, in particular in industrial environments where built-in solutions are sought. A battery of implementation tests are presented in Part II, where the experimental endorsement of the model is included.

  6. Integration of Error Compensation of Coordinate Measuring Machines into Feature Measurement: Part I—Model Development

    PubMed Central

    Calvo, Roque; D’Amato, Roberto; Gómez, Emilio; Domingo, Rosario

    2016-01-01

    The development of an error compensation model for coordinate measuring machines (CMMs) and its integration into feature measurement is presented. CMMs are widespread and dependable instruments in industry and laboratories for dimensional measurement. From the tip probe sensor to the machine display, there is a complex transformation of probed point coordinates through the geometrical feature model that makes the assessment of accuracy and uncertainty measurement results difficult. Therefore, error compensation is not standardized, conversely to other simpler instruments. Detailed coordinate error compensation models are generally based on CMM as a rigid-body and it requires a detailed mapping of the CMM’s behavior. In this paper a new model type of error compensation is proposed. It evaluates the error from the vectorial composition of length error by axis and its integration into the geometrical measurement model. The non-explained variability by the model is incorporated into the uncertainty budget. Model parameters are analyzed and linked to the geometrical errors and uncertainty of CMM response. Next, the outstanding measurement models of flatness, angle, and roundness are developed. The proposed models are useful for measurement improvement with easy integration into CMM signal processing, in particular in industrial environments where built-in solutions are sought. A battery of implementation tests are presented in Part II, where the experimental endorsement of the model is included. PMID:27690052

  7. A simple procedure to include a free-form measurement capability to standard coordinate measurement machines

    NASA Astrophysics Data System (ADS)

    Schneider, Florian; Rascher, Rolf; Stamp, Richard; Smith, Gordon

    2013-09-01

    The modern optical industry requires objects with complex topographical structures. Free-form shaped objects are of large interest in many branches, especially for size reduced, modern lifestyle products like digital cameras. State of the art multi-axes-coordinate measurement machines (CMM), like the topographical measurement machine TII-3D, are by principle suitable to measure free-form shaped objects. The only limitation is the software package. This paper may illustrate a simple way to enhance coordinate measurement machines in order to add a free-form function. Next to a coordinate measurement machine, only a state of the art CAD† system and a simple piece of software are necessary. For this paper, the CAD software CREO‡ had been used. CREO enables the user to develop a 3D object in two different ways. With the first method, the user might design the shape by drawing one or more 2D sketches and put an envelope around. Using the second method, the user could define one or more formulas in the editor to describe the favoured surface. Both procedures lead to the required three-dimensional shape. However, further features of CREO enable the user to export the XYZ-coordinates of the created surface. A special designed software tool, developed with Matlab§, converts the XYZ-file into a measurement matrix which can be used as a reference file. Finally the result of the free-form measurement, carried out with a CMM, has to be loaded into the software tool and both files will be computed. The result is an error profile which provides the deviation between the measurement and the target-geometry.

  8. Dynamics between Cancer Cell Subpopulations Reveals a Model Coordinating with Both Hierarchical and Stochastic Concepts

    PubMed Central

    Wang, Weikang; Quan, Yi; Fu, Qibin; Liu, Yu; Liang, Ying; Wu, Jingwen; Yang, Gen; Luo, Chunxiong; Ouyang, Qi; Wang, Yugang

    2014-01-01

    Tumors are often heterogeneous in which tumor cells of different phenotypes have distinct properties. For scientific and clinical interests, it is of fundamental importance to understand their properties and the dynamic variations among different phenotypes, specifically under radio- and/or chemo-therapy. Currently there are two controversial models describing tumor heterogeneity, the cancer stem cell (CSC) model and the stochastic model. To clarify the controversy, we measured probabilities of different division types and transitions of cells via in situ immunofluorescence. Based on the experiment data, we constructed a model that combines the CSC with the stochastic concepts, showing the existence of both distinctive CSC subpopulations and the stochastic transitions from NSCCs to CSCs. The results showed that the dynamic variations between CSCs and non-stem cancer cells (NSCCs) can be simulated with the model. Further studies also showed that the model can be used to describe the dynamics of the two subpopulations after radiation treatment. More importantly, analysis demonstrated that the experimental detectable equilibrium CSC proportion can be achieved only when the stochastic transitions from NSCCs to CSCs occur, indicating that tumor heterogeneity may exist in a model coordinating with both the CSC and the stochastic concepts. The mathematic model based on experimental parameters may contribute to a better understanding of the tumor heterogeneity, and provide references on the dynamics of CSC subpopulation during radiotherapy. PMID:24416258

  9. Imperfection and Thickness Measurement of Panels Using a Coordinate Measurement Machine

    NASA Technical Reports Server (NTRS)

    Thornburgh, Robert P.

    2006-01-01

    This paper summarizes the methodology used to measure imperfection and thickness variation for flat and curved panels using a Coordinate Measurement Machine (CMM) and the software program MeasPanel. The objective is to provide a reference document so that someone with a basic understanding of CMM operation can measure a panel with minimal training. Detailed information about both the measurement system setup and computer software is provided. Information is also provided about the format of the raw data, as well as how it is post-processed for use in finite-element analysis.

  10. Stochastic evolutionary dynamics in minimum-effort coordination games

    NASA Astrophysics Data System (ADS)

    Li, Kun; Cong, Rui; Wang, Long

    2016-08-01

    The minimum-effort coordination game draws recently more attention for the fact that human behavior in this social dilemma is often inconsistent with the predictions of classical game theory. Here, we combine evolutionary game theory and coalescence theory to investigate this game in finite populations. Both analytic results and individual-based simulations show that effort costs play a key role in the evolution of contribution levels, which is in good agreement with those observed experimentally. Besides well-mixed populations, set structured populations have also been taken into consideration. Therein we find that large number of sets and moderate migration rate greatly promote effort levels, especially for high effort costs.

  11. Incorporating coordination dynamics into an evolutionarily grounded science of intentional change.

    PubMed

    Kostrubiec, Viviane; Kelso, J A Scott

    2014-08-01

    We suggest the authors' endeavor toward a science of intentional change may benefit from recent advances in informationally meaningful self-organizing dynamical systems. Coordination Dynamics, having contributed to an understanding of behavior on several time scales - adaptation, learning, and development - and on different levels of analysis, from the neural to the social, may complement, if not enhance, the authors' insights.

  12. Mg2+ coordinating dynamics in Mg:ATP fueled motor proteins

    NASA Astrophysics Data System (ADS)

    Bojovschi, A.; Liu, Ming S.; Sadus, Richard J.

    2014-03-01

    The coordination of Mg2+ with the triphosphate group of adenosine triphosphate (ATP) in motor proteins is investigated using data mining and molecular dynamics. The possible coordination structures available from crystal data for actin, myosin, RNA polymerase, DNA polymerase, DNA helicase, and F1-ATPase are verified and investigated further by molecular dynamics. Coordination states are evaluated using structural analysis and quantified by radial distribution functions, coordination numbers, and pair interaction energy calculations. The results reveal a diverse range of both transitory and stable coordination arrangements between Mg2+ and ATP. The two most stable coordinating states occur when Mg2+ coordinates two or three oxygens from the triphosphate group of ATP. Evidence for five-site coordination is also reported involving water in addition to the triphosphate group. The stable states correspond to a pair interaction energy of either ˜-2750 kJ/mol or -3500 kJ/mol. The role of water molecules in the hydration shell surrounding Mg2+ is also reported.

  13. Third post-Newtonian constrained canonical dynamics for binary point masses in harmonic coordinates

    NASA Astrophysics Data System (ADS)

    Memmesheimer, Raoul-Martin; Schäfer, Gerhard

    2005-02-01

    The conservative dynamics of two point masses given in harmonic coordinates up to the third post-Newtonian order is treated within the framework of constrained canonical dynamics. A representation of the approximate Poincaré algebra is constructed with the aid of Dirac brackets. Uniqueness of the generators of the Poincaré group or the integrals of motion is achieved by imposing their action on the point mass coordinates to be identical with that of the usual infinitesimal Poincaré transformations. The second post-Coulombian approximation to the dynamics of two point charges as predicted by Feynman-Wheeler electrodynamics in Lorentz gauge is treated similarly.

  14. Approximating high-dimensional dynamics by barycentric coordinates with linear programming.

    PubMed

    Hirata, Yoshito; Shiro, Masanori; Takahashi, Nozomu; Aihara, Kazuyuki; Suzuki, Hideyuki; Mas, Paloma

    2015-01-01

    The increasing development of novel methods and techniques facilitates the measurement of high-dimensional time series but challenges our ability for accurate modeling and predictions. The use of a general mathematical model requires the inclusion of many parameters, which are difficult to be fitted for relatively short high-dimensional time series observed. Here, we propose a novel method to accurately model a high-dimensional time series. Our method extends the barycentric coordinates to high-dimensional phase space by employing linear programming, and allowing the approximation errors explicitly. The extension helps to produce free-running time-series predictions that preserve typical topological, dynamical, and/or geometric characteristics of the underlying attractors more accurately than the radial basis function model that is widely used. The method can be broadly applied, from helping to improve weather forecasting, to creating electronic instruments that sound more natural, and to comprehensively understanding complex biological data.

  15. Approximating high-dimensional dynamics by barycentric coordinates with linear programming

    SciTech Connect

    Hirata, Yoshito Aihara, Kazuyuki; Suzuki, Hideyuki; Shiro, Masanori; Takahashi, Nozomu; Mas, Paloma

    2015-01-15

    The increasing development of novel methods and techniques facilitates the measurement of high-dimensional time series but challenges our ability for accurate modeling and predictions. The use of a general mathematical model requires the inclusion of many parameters, which are difficult to be fitted for relatively short high-dimensional time series observed. Here, we propose a novel method to accurately model a high-dimensional time series. Our method extends the barycentric coordinates to high-dimensional phase space by employing linear programming, and allowing the approximation errors explicitly. The extension helps to produce free-running time-series predictions that preserve typical topological, dynamical, and/or geometric characteristics of the underlying attractors more accurately than the radial basis function model that is widely used. The method can be broadly applied, from helping to improve weather forecasting, to creating electronic instruments that sound more natural, and to comprehensively understanding complex biological data.

  16. Computing reaching dynamics in motor cortex with Cartesian spatial coordinates.

    PubMed

    Tanaka, Hirokazu; Sejnowski, Terrence J

    2013-02-01

    How neurons in the primary motor cortex control arm movements is not yet understood. Here we show that the equations of motion governing reaching simplify when expressed in spatial coordinates. In this fixed reference frame, joint torques are the sums of vector cross products between the spatial positions of limb segments and their spatial accelerations and velocities. The consequences that follow from this model explain many properties of neurons in the motor cortex, including directional broad, cosinelike tuning, nonuniformly distributed preferred directions dependent on the workspace, and the rotation of the population vector during arm movements. Remarkably, the torques can be directly computed as a linearly weighted sum of responses from cortical motoneurons, and the muscle tensions can be obtained as rectified linear sums of the joint torques. This allows the required muscle tensions to be computed rapidly from a trajectory in space with a feedforward network model.

  17. General Tortoise Coordinate Transformation in a Dynamical Kerr-Newman Black Hole

    NASA Astrophysics Data System (ADS)

    Liu, Xian-Ming; Cheng, Su-Jun; Liu, Wen-Biao

    2012-02-01

    Under the extended dynamical tortoise coordinate transformation, Damour-Ruffini method has been applied to calculate the charged particles' Hawking radiation from the apparent horizon of a dynamical Kerr-Newman black hole. It is shown that Hawking radiation is still purely thermal black body spectrum. Moreover, the temperature of Hawking radiation is corresponding to the apparent horizon surface gravity and the first law of thermodynamics can also be constructed successfully on the apparent horizon in the dynamical Kerr-Newman black hole.

  18. Measuring large aspherics using a commercially available 3D-coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Otto, Wolfgang; Matthes, Axel; Schiehle, Heinz

    2000-07-01

    A CNC-controlled precision measuring machine is a very powerful tool in the optical shop not only to determine the surface figure, but also to qualify the radius of curvature and conic constant of aspherics. We used a commercially available 3D-coordinate measuring machine (CMM, ZEISS UPMC 850 CARAT S-ACC) to measure the shape of the GEMINI 1-m convex secondary mirrors at different lapping and polishing stages. To determine the measuring accuracy we compared the mechanical measurements with the results achieved by means of an interferometrical test setup. The data obtained in an early stage of polishing were evaluated in Zernike polynomials which show a very good agreement. The deviation concerning long wave rotational symmetrical errors was 20 nm rms, whereas the accuracy measuring of mid spatial frequency deviations was limited to about 100 nm rms.

  19. Emergent complexity matching in interpersonal coordination: Local dynamics and global variability.

    PubMed

    Fine, Justin M; Likens, Aaron D; Amazeen, Eric L; Amazeen, Polemnia G

    2015-06-01

    Rhythmic coordination with stimuli and other people's movements containing variable or unpredictable fluctuations might involve distinct processes: detecting the fluctuation structure and tuning to or matching the structure's temporal complexity. This framework predicts that global tuning and local parameter adjustments (e.g., position, velocity or phase) can operate independently during coordination (Marmelat & Delignières, 2012). Alternatively, we propose that complexity matching is a result of local phase adjustments during coordination (Delignières & Marmelat, 2014; Torre, Varlet, & Marmelat, 2013). The current study examined this relationship in a rhythmic interpersonal coordination task. Dyads coordinated swinging pendulums that differed in their uncoupled frequencies (detuning). We predicted that frequency detuning would require increased local corrections to maintain the intended phase pattern (in phase). This was expected to yield a relative phase shift accompanied by a change in period complexity and matching. Experimental data and numerical modeling of the pendulum dynamics confirmed our predictions. Increased relative phase shifts occurred simultaneously with increased dissociation between individuals' movement period complexity. This provided evidence that global complexity matching is intricately linked to local movement adjustments and is not a distinct coordination mechanism. These findings are considered with respect to dynamical and computational approaches to interpersonal coordination.

  20. Dynamic indocyanine green angiography measurements

    PubMed Central

    Invernizzi, Alessandro; Larkin, Sean; Staurenghi, Giovanni

    2012-01-01

    Abstract. Dynamic indocyanine green imaging uses a scanning laser ophthalmoscope and a fluorescent dye to produce movies of the dye-filling pattern in the retina and choroid of the eye. It is used for evaluating choroidal neovascularization. Movies are examined to identify the anatomy of the pathology for planning treatment and to evaluate progression or response to treatment. The popularity of this approach is affected by the complexity and difficulty in interpreting the movies. Software algorithms were developed to produce images from the movies that are easy to interpret. A mathematical model is formulated of the flow dynamics, and a fitting algorithm is designed that solves for the flow parameters. The images provide information about flow and perfusion, including regions of change between examinations. Imaged measures include the dye fill-time, temporal dispersion, and magnitude of the dye dilution temporal curves associated with image pixels. Cases show how the software can help to identify clinically relevant anatomy such as feeder vessels, drain vessels, capillary networks, and normal choroidal draining vessels. As a potential tool for research into the character of neovascular conditions and treatments, it reveals the flow dynamics and character of the lesion. Future varieties of this methodology may be used for evaluating the success of engineered tissue transplants, surgical flaps, reconstructive surgery, breast surgery, and many other surgical applications where flow, perfusion, and vascularity of tissue are important. PMID:23192382

  1. Dynamic indocyanine green angiography measurements

    NASA Astrophysics Data System (ADS)

    Holmes, Timothy; Invernizzi, Alessandro; Larkin, Sean; Staurenghi, Giovanni

    2012-11-01

    Dynamic indocyanine green imaging uses a scanning laser ophthalmoscope and a fluorescent dye to produce movies of the dye-filling pattern in the retina and choroid of the eye. It is used for evaluating choroidal neovascularization. Movies are examined to identify the anatomy of the pathology for planning treatment and to evaluate progression or response to treatment. The popularity of this approach is affected by the complexity and difficulty in interpreting the movies. Software algorithms were developed to produce images from the movies that are easy to interpret. A mathematical model is formulated of the flow dynamics, and a fitting algorithm is designed that solves for the flow parameters. The images provide information about flow and perfusion, including regions of change between examinations. Imaged measures include the dye fill-time, temporal dispersion, and magnitude of the dye dilution temporal curves associated with image pixels. Cases show how the software can help to identify clinically relevant anatomy such as feeder vessels, drain vessels, capillary networks, and normal choroidal draining vessels. As a potential tool for research into the character of neovascular conditions and treatments, it reveals the flow dynamics and character of the lesion. Future varieties of this methodology may be used for evaluating the success of engineered tissue transplants, surgical flaps, reconstructive surgery, breast surgery, and many other surgical applications where flow, perfusion, and vascularity of tissue are important.

  2. Dynamical calculation of crystal truncation rods for surfaces and interfaces using a Cartesian coordinate transformation technique.

    PubMed

    Chien; Gau; Chang; Stetsko

    1999-07-01

    A dynamical calculation scheme that employs Cartesian coordinates with a z axis normal to the crystal surface to define polarization unit vectors and wavefields is applied to interpret the intensity distribution of crystal truncation rods for surfaces and interfaces. A comparison between this calculation scheme and the asymptotic iteration approach using the conventional presentation of the polarization components of the wavefields, with the sigma and pi components perpendicular to the wavevectors, is presented. It is found that the use of Cartesian coordinate systems can provide correct boundary conditions in determining the wavefield amplitudes, thus leading to a rigorous and general calculation scheme for dynamical diffraction from surfaces and interfaces.

  3. Dynamic Fluctuation of U(3+) Coordination Structure in the Molten LiCl-KCl Eutectic via First Principles Molecular Dynamics Simulations.

    PubMed

    Li, Xuejiao; Song, Jia; Shi, Shuping; Yan, Liuming; Zhang, Zhaochun; Jiang, Tao; Peng, Shuming

    2017-01-26

    The dynamic fluctuation of the U(3+) coordination structure in a molten LiCl-KCl mixture was studied using first principles molecular dynamics (FPMD) simulations. The radial distribution function, probability distribution of coordination numbers, fluctuation of coordination number and cage volume, self-diffusion coefficient and solvodynamic mean radius of U(3+), dynamics of the nearest U-Cl distances, and van Hove function were evaluated. It was revealed that fast exchange of Cl(-) occurred between the first and second coordination shells of U(3+) accompanied with fast fluctuation of coordination number and rearrangement of coordination structure. It was concluded that 6-fold coordination structure dominated the coordination structure of U(3+) in the molten LiCl-KCl-UCl3 mixture and a high temperature was conducive to the formation of low coordinated structure.

  4. Study on technology of double parallel-joints coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Xia, Guisuo; Liao, Cheng; Yu, Runqiao; Fu, Yanjun

    2013-10-01

    The research of the high accuracy coordinate measuring machine is now playing a more and more considerable role in heightening the technical level of equipment manufacturing industry. With reference to the characteristics of foreign ScanMax coordinate measuring machine, this paper introduces the development of a double parallel-joint coordinate measuring machine with our own dependent intellectual property. This paper details the structural design, the calibration method and the evaluation for the uncertainty measurement of a prototype. The prototype has several advantages when compared with foreign instruments: first, decrease of Abbe error; second, enlargement of the measuring range; third, improvement of the rigidity of the instrument. The measurement test indicates that the measurement uncertainty (when K=2) of special random distance is 10.2 μm. The double parallel-joint coordinate measuring machine studied by this paper is of great academic value and the developed prototype is highly practical and worthy of being popularized.

  5. Application of a virtual coordinate measuring machine for measurement uncertainty estimation of aspherical lens parameters

    NASA Astrophysics Data System (ADS)

    Küng, Alain; Meli, Felix; Nicolet, Anaïs; Thalmann, Rudolf

    2014-09-01

    Tactile ultra-precise coordinate measuring machines (CMMs) are very attractive for accurately measuring optical components with high slopes, such as aspheres. The METAS µ-CMM, which exhibits a single point measurement repeatability of a few nanometres, is routinely used for measurement services of microparts, including optical lenses. However, estimating the measurement uncertainty is very demanding. Because of the many combined influencing factors, an analytic determination of the uncertainty of parameters that are obtained by numerical fitting of the measured surface points is almost impossible. The application of numerical simulation (Monte Carlo methods) using a parametric fitting algorithm coupled with a virtual CMM based on a realistic model of the machine errors offers an ideal solution to this complex problem: to each measurement data point, a simulated measurement variation calculated from the numerical model of the METAS µ-CMM is added. Repeated several hundred times, these virtual measurements deliver the statistical data for calculating the probability density function, and thus the measurement uncertainty for each parameter. Additionally, the eventual cross-correlation between parameters can be analyzed. This method can be applied for the calibration and uncertainty estimation of any parameter of the equation representing a geometric element. In this article, we present the numerical simulation model of the METAS µ-CMM and the application of a Monte Carlo method for the uncertainty estimation of measured asphere parameters.

  6. Coordination dynamics in a socially situated nervous system

    PubMed Central

    Coey, Charles A.; Varlet, Manuel; Richardson, Michael J.

    2012-01-01

    Traditional theories of cognitive science have typically accounted for the organization of human behavior by detailing requisite computational/representational functions and identifying neurological mechanisms that might perform these functions. Put simply, such approaches hold that neural activity causes behavior. This same general framework has been extended to accounts of human social behavior via concepts such as “common-coding” and “co-representation” and much recent neurological research has been devoted to brain structures that might execute these social-cognitive functions. Although these neural processes are unquestionably involved in the organization and control of human social interactions, there is good reason to question whether they should be accorded explanatory primacy. Alternatively, we propose that a full appreciation of the role of neural processes in social interactions requires appropriately situating them in their context of embodied-embedded constraints. To this end, we introduce concepts from dynamical systems theory and review research demonstrating that the organization of human behavior, including social behavior, can be accounted for in terms of self-organizing processes and lawful dynamics of animal-environment systems. Ultimately, we hope that these alternative concepts can complement the recent advances in cognitive neuroscience and thereby provide opportunities to develop a complete and coherent account of human social interaction. PMID:22701413

  7. Coordinated DNA dynamics during the human telomerase catalytic cycle

    NASA Astrophysics Data System (ADS)

    Parks, Joseph W.; Stone, Michael D.

    2014-06-01

    The human telomerase reverse transcriptase (hTERT) utilizes a template within the integral RNA subunit (hTR) to direct extension of telomeres. Telomerase exhibits repeat addition processivity (RAP) and must therefore translocate the nascent DNA product into a new RNA:DNA hybrid register to prime each round of telomere repeat synthesis. Here, we use single-molecule FRET and nuclease protection assays to monitor telomere DNA structure and dynamics during the telomerase catalytic cycle. DNA translocation during RAP proceeds through a previously uncharacterized kinetic substep during which the 3‧-end of the DNA substrate base pairs downstream within the hTR template. The rate constant for DNA primer realignment reveals this step is not rate limiting for RAP, suggesting a second slow conformational change repositions the RNA:DNA hybrid into the telomerase active site and drives the extrusion of the 5‧-end of the DNA primer out of the enzyme complex.

  8. Motion Coordination with Noisy Measurement in Natural and Artificial Swarms

    DTIC Science & Technology

    2006-11-01

    attacks. Canadian Journal of Zoology, 77:1540–1546, 1999. A. Okubo. Dynamical aspects of animal grouping: swarms, schools, flocks, and herds. Advances in...robotic swarms, these results shed light on the dynamics of collective motion of certain animal groups. I. INTRODUCTION Distributed control algorithms...grant DAAD19-03-D-0004 from the U.S. Army Research Office and by the National Science Foundation under Grant No. CCR-0311084 relevant in the study of

  9. The difficult chore of measuring coordination by EXAFS.

    SciTech Connect

    Ravel, B.; Kelly, S. D.; Biosciences Division

    2007-01-01

    Neither the theory nor the interpretation of Extended X-Ray-Absorption Fine-Structure (EXAFS) spectroscopy requires assumptions of crystalline symmetry or periodicity. As a result, EXAFS is a tool applied to a wide range of scientific disciplines and to a wide variety of experimental systems. A simple enumeration of the atoms in the coordination environment of the absorber is often the primary goal of an EXAFS experiment. There are, however, a number of pitfalls in the way of an accurate determination of coordination number (CN). These include statistical limitations of the EXAFS fitting problem, empirical effects due to sample preparation, and the assumptions made about the physical structure surrounding the absorber in the course of data analysis. In this paper we examine several of these pitfalls and their effects upon the determination of CN. Where possible, we offer suggestions for avoiding or mitigating the pitfalls. We hope this paper will help guide the general EXAFS practitioner through the difficult chore of accurately determining CN.

  10. The Difficult Chore of Measuring Coordination by EXAFS

    SciTech Connect

    Ravel, B.; Kelly, S. D.

    2007-02-02

    Neither the theory nor the interpretation of Extended X-Ray-Absorption Fine-Structure (EXAFS) spectroscopy requires assumptions of crystalline symmetry or periodicity. As a result, EXAFS is a tool applied to a wide range of scientific disciplines and to a wide variety of experimental systems. A simple enumeration of the atoms in the coordination environment of the absorber is often the primary goal of an EXAFS experiment. There are, however, a number of pitfalls in the way of an accurate determination of coordination number (CN). These include statistical limitations of the EXAFS fitting problem, empirical effects due to sample preparation, and the assumptions made about the physical structure surrounding the absorber in the course of data analysis. In this paper we examine several of these pitfalls and their effects upon the determination of CN. Where possible, we offer suggestions for avoiding or mitigating the pitfalls. We hope this paper will help guide the general EXAFS practitioner through the difficult chore of accurately determining CN.

  11. Milking the spherical cow - on aspherical dynamics in spherical coordinates

    NASA Astrophysics Data System (ADS)

    Pontzen, Andrew; Read, Justin I.; Teyssier, Romain; Governato, Fabio; Gualandris, Alessia; Roth, Nina; Devriendt, Julien

    2015-08-01

    Galaxies and the dark matter haloes that host them are not spherically symmetric, yet spherical symmetry is a helpful simplifying approximation for idealized calculations and analysis of observational data. The assumption leads to an exact conservation of angular momentum for every particle, making the dynamics unrealistic. But how much does that inaccuracy matter in practice for analyses of stellar distribution functions, collisionless relaxation, or dark matter core-creation? We provide a general answer to this question for a wide class of aspherical systems; specifically, we consider distribution functions that are `maximally stable', i.e. that do not evolve at first order when external potentials (which arise from baryons, large-scale tidal fields or infalling substructure) are applied. We show that a spherically symmetric analysis of such systems gives rise to the false conclusion that the density of particles in phase space is ergodic (a function of energy alone). Using this idea we are able to demonstrate that: (a) observational analyses that falsely assume spherical symmetry are made more accurate by imposing a strong prior preference for near-isotropic velocity dispersions in the centre of spheroids; (b) numerical simulations that use an idealized spherically symmetric setup can yield misleading results and should be avoided where possible; and (c) triaxial dark matter haloes (formed in collisionless cosmological simulations) nearly attain our maximally stable limit, but their evolution freezes out before reaching it.

  12. Coordinated Dynamics of RNA Splicing Speckles in the Nucleus.

    PubMed

    Zhang, Qiao; Kota, Krishna P; Alam, Samer G; Nickerson, Jeffrey A; Dickinson, Richard B; Lele, Tanmay P

    2016-06-01

    Despite being densely packed with chromatin, nuclear bodies and a nucleoskeletal network, the nucleus is a remarkably dynamic organelle. Chromatin loops form and relax, RNA transcripts and transcription factors move diffusively, and nuclear bodies move. We show here that RNA splicing speckled domains (splicing speckles) fluctuate in constrained nuclear volumes and remodel their shapes. Small speckles move in a directed way toward larger speckles with which they fuse. This directed movement is reduced upon decreasing cellular ATP levels or inhibiting RNA polymerase II activity. The random movement of speckles is reduced upon decreasing cellular ATP levels, moderately reduced after inhibition of SWI/SNF chromatin remodeling and modestly increased upon inhibiting RNA polymerase II activity. To define the paths through which speckles can translocate in the nucleus, we generated a pressure gradient to create flows in the nucleus. In response to the pressure gradient, speckles moved along curvilinear paths in the nucleus. Collectively, our results demonstrate a new type of ATP-dependent motion in the nucleus. We present a model where recycling splicing factors return as part of small sub-speckles from distal sites of RNA processing to larger splicing speckles by a directed ATP-driven mechanism through interchromatin spaces.

  13. Motor learning of novel dynamics is not represented in a single global coordinate system: evaluation of mixed coordinate representations and local learning.

    PubMed

    Berniker, Max; Franklin, David W; Flanagan, J Randall; Wolpert, Daniel M; Kording, Konrad

    2014-03-01

    Successful motor performance requires the ability to adapt motor commands to task dynamics. A central question in movement neuroscience is how these dynamics are represented. Although it is widely assumed that dynamics (e.g., force fields) are represented in intrinsic, joint-based coordinates (Shadmehr R, Mussa-Ivaldi FA. J Neurosci 14: 3208-3224, 1994), recent evidence has questioned this proposal. Here we reexamine the representation of dynamics in two experiments. By testing generalization following changes in shoulder, elbow, or wrist configurations, the first experiment tested for extrinsic, intrinsic, or object-centered representations. No single coordinate frame accounted for the pattern of generalization. Rather, generalization patterns were better accounted for by a mixture of representations or by models that assumed local learning and graded, decaying generalization. A second experiment, in which we replicated the design of an influential study that had suggested encoding in intrinsic coordinates (Shadmehr and Mussa-Ivaldi 1994), yielded similar results. That is, we could not find evidence that dynamics are represented in a single coordinate system. Taken together, our experiments suggest that internal models do not employ a single coordinate system when generalizing and may well be represented as a mixture of coordinate systems, as a single system with local learning, or both.

  14. Motor learning of novel dynamics is not represented in a single global coordinate system: evaluation of mixed coordinate representations and local learning

    PubMed Central

    Franklin, David W.; Flanagan, J. Randall; Wolpert, Daniel M.; Kording, Konrad

    2013-01-01

    Successful motor performance requires the ability to adapt motor commands to task dynamics. A central question in movement neuroscience is how these dynamics are represented. Although it is widely assumed that dynamics (e.g., force fields) are represented in intrinsic, joint-based coordinates (Shadmehr R, Mussa-Ivaldi FA. J Neurosci 14: 3208–3224, 1994), recent evidence has questioned this proposal. Here we reexamine the representation of dynamics in two experiments. By testing generalization following changes in shoulder, elbow, or wrist configurations, the first experiment tested for extrinsic, intrinsic, or object-centered representations. No single coordinate frame accounted for the pattern of generalization. Rather, generalization patterns were better accounted for by a mixture of representations or by models that assumed local learning and graded, decaying generalization. A second experiment, in which we replicated the design of an influential study that had suggested encoding in intrinsic coordinates (Shadmehr and Mussa-Ivaldi 1994), yielded similar results. That is, we could not find evidence that dynamics are represented in a single coordinate system. Taken together, our experiments suggest that internal models do not employ a single coordinate system when generalizing and may well be represented as a mixture of coordinate systems, as a single system with local learning, or both. PMID:24353296

  15. Tortoise coordinate and Hawking effect in a dynamical Kerr black hole

    NASA Astrophysics Data System (ADS)

    Yang, Jian; Zhao, Zheng; Liu, Wenbiao

    2011-02-01

    Hawking effect from a dynamical Kerr black hole is investigated using the improved Damour-Ruffini method with a new tortoise coordinate transformation. Hawking temperature of the black hole can be obtained point by point at the event horizon. It is found that Hawking temperatures of different points on the surface are different. Moreover, the temperature does not turn to zero while the dynamical black hole turns to an extreme one.

  16. [Coordination patterns assessed by a continuous measure of joints coupling during upper limb repetitive movements].

    PubMed

    Draicchio, F; Silvetti, A; Ranavolo, A; Iavicoli, S

    2008-01-01

    We analyzed the coordination patterns between elbow, shoulder and trunk in a motor task consisting of reaching out, picking up a cylinder, and transporting it back by using the Dynamical Systems Theory and calculating the continuous relative phase (CRP), a continuous measure of the coupling between two interacting joints. We used an optoelectronic motion analysis system consisting of eight infra-red ray cameras to detect the movements of nine skin-mounted markers. We calculated the root square of the adjusted coefficient of determination, the coefficient of multiple correlation (CMC), in order to investigate the repeatability of the joints coordination. The data confirm that the CNS establishes both synergic (i.e. coupling between shoulder and trunk on the frontal plane) and hierarchical (i.e. coupling between elbow-shoulder-trunk on the horizontal plane) relationships among the available degrees of freedom to overcome the complexity due to motor redundancy. The present study describes a method to investigate the organization of the kinematic degrees of freedom during upper limb multi-joint motor tasks that can be useful to assess upper limb repetitive movements.

  17. Evolutionary dynamics of the traveler's dilemma and minimum-effort coordination games on complex networks

    NASA Astrophysics Data System (ADS)

    Iyer, Swami; Killingback, Timothy

    2014-10-01

    The traveler's dilemma game and the minimum-effort coordination game are social dilemmas that have received significant attention resulting from the fact that the predictions of classical game theory are inconsistent with the results found when the games are studied experimentally. Moreover, both the traveler's dilemma and the minimum-effort coordination games have potentially important applications in evolutionary biology. Interestingly, standard deterministic evolutionary game theory, as represented by the replicator dynamics in a well-mixed population, is also inadequate to account for the behavior observed in these games. Here we study the evolutionary dynamics of both these games in populations with interaction patterns described by a variety of complex network topologies. We investigate the evolutionary dynamics of these games through agent-based simulations on both model and empirical networks. In particular, we study the effects of network clustering and assortativity on the evolutionary dynamics of both games. In general, we show that the evolutionary behavior of the traveler's dilemma and minimum-effort coordination games on complex networks is in good agreement with that observed experimentally. Thus, formulating the traveler's dilemma and the minimum-effort coordination games on complex networks neatly resolves the paradoxical aspects of these games.

  18. Evolutionary dynamics of the traveler's dilemma and minimum-effort coordination games on complex networks.

    PubMed

    Iyer, Swami; Killingback, Timothy

    2014-10-01

    The traveler's dilemma game and the minimum-effort coordination game are social dilemmas that have received significant attention resulting from the fact that the predictions of classical game theory are inconsistent with the results found when the games are studied experimentally. Moreover, both the traveler's dilemma and the minimum-effort coordination games have potentially important applications in evolutionary biology. Interestingly, standard deterministic evolutionary game theory, as represented by the replicator dynamics in a well-mixed population, is also inadequate to account for the behavior observed in these games. Here we study the evolutionary dynamics of both these games in populations with interaction patterns described by a variety of complex network topologies. We investigate the evolutionary dynamics of these games through agent-based simulations on both model and empirical networks. In particular, we study the effects of network clustering and assortativity on the evolutionary dynamics of both games. In general, we show that the evolutionary behavior of the traveler's dilemma and minimum-effort coordination games on complex networks is in good agreement with that observed experimentally. Thus, formulating the traveler's dilemma and the minimum-effort coordination games on complex networks neatly resolves the paradoxical aspects of these games.

  19. Noise and Low-Level Dynamics Can Coordinate Multicomponent Bet Hedging Mechanisms

    PubMed Central

    Garcia-Bernardo, Javier; Dunlop, Mary J.

    2015-01-01

    To counter future uncertainty, cells can stochastically express stress response mechanisms to diversify their population and hedge against stress. This approach allows a small subset of the population to survive without the prohibitive cost of constantly expressing resistance machinery at the population level. However, expression of multiple genes in concert is often needed to ensure survival, requiring coordination of infrequent events across many downstream targets. This raises the question of how cells orchestrate the timing of multiple rare events without adding cost. To investigate this, we used a stochastic model to study regulation of downstream target genes by a transcription factor. We compared several upstream regulator profiles, including constant expression, pulsatile dynamics, and noisy expression. We found that pulsatile dynamics and noise are sufficient to coordinate expression of multiple downstream genes. Notably, this is true even when fluctuations in the upstream regulator are far below the dissociation constants of the regulated genes, as with infrequently activated genes. As an example, we simulated the dynamics of the multiple antibiotic resistance activator (MarA) and 40 diverse downstream genes it regulates, determining that low-level dynamics in MarA are sufficient to coordinate expression of resistance mechanisms. We also demonstrated that noise can play a similar coordinating role. Importantly, we found that these benefits are present without a corresponding increase in the population-level cost. Therefore, our model suggests that low-level dynamics or noise in a transcription factor can coordinate expression of multiple stress response mechanisms by engaging them simultaneously without adding to the overall cost. PMID:25564865

  20. Potential accuracy of measuring the angular coordinates of signal sources and accuracy of measuring them using optimal spatial filtration

    NASA Astrophysics Data System (ADS)

    Kalenov, E. N.

    2015-03-01

    The paper investigates the potential accuracy of measuring the angular coordinates of a signal source in the presence of interference sources, as well as the accuracy of measuring these coordinates via the formation of a signal's spatial spectrum using optimal spatial filtration. For a linear equidistant array, analytical solutions are obtained that determine the dependence of the accuracies in measuring the angular coordinates on the array parameters, the angular distance to the noise source, and spectral power densities of a signal, noise, and an interference source.

  1. Integration of Error Compensation of Coordinate Measuring Machines into Feature Measurement: Part II—Experimental Implementation

    PubMed Central

    Calvo, Roque; D’Amato, Roberto; Gómez, Emilio; Domingo, Rosario

    2016-01-01

    Coordinate measuring machines (CMM) are main instruments of measurement in laboratories and in industrial quality control. A compensation error model has been formulated (Part I). It integrates error and uncertainty in the feature measurement model. Experimental implementation for the verification of this model is carried out based on the direct testing on a moving bridge CMM. The regression results by axis are quantified and compared to CMM indication with respect to the assigned values of the measurand. Next, testing of selected measurements of length, flatness, dihedral angle, and roundness features are accomplished. The measurement of calibrated gauge blocks for length or angle, flatness verification of the CMM granite table and roundness of a precision glass hemisphere are presented under a setup of repeatability conditions. The results are analysed and compared with alternative methods of estimation. The overall performance of the model is endorsed through experimental verification, as well as the practical use and the model capability to contribute in the improvement of current standard CMM measuring capabilities. PMID:27754441

  2. Principal component analysis of molecular dynamics: on the use of Cartesian vs. internal coordinates.

    PubMed

    Sittel, Florian; Jain, Abhinav; Stock, Gerhard

    2014-07-07

    Principal component analysis of molecular dynamics simulations is a popular method to account for the essential dynamics of the system on a low-dimensional free energy landscape. Using Cartesian coordinates, first the translation and overall rotation need to be removed from the trajectory. Since the rotation depends via the moment of inertia on the molecule's structure, this separation is only straightforward for relatively rigid systems. Adopting millisecond molecular dynamics simulations of the folding of villin headpiece and the functional dynamics of BPTI provided by D. E. Shaw Research, it is demonstrated via a comparison of local and global rotational fitting that the structural dynamics of flexible molecules necessarily results in a mixing of overall and internal motion. Even for the small-amplitude functional motion of BPTI, the conformational distribution obtained from a Cartesian principal component analysis therefore reflects to some extend the dominant overall motion rather than the much smaller internal motion of the protein. Internal coordinates such as backbone dihedral angles, on the other hand, are found to yield correct and well-resolved energy landscapes for both examples. The virtues and shortcomings of the choice of various fitting schemes and coordinate sets as well as the generality of these results are discussed in some detail.

  3. The dynamics of zinc sites in proteins: electronic basis for coordination sphere expansion at structural sites.

    PubMed

    Daniel, A Gerard; Farrell, Nicholas P

    2014-12-01

    The functional role assumed by zinc in proteins is closely tied to the variable dynamics around its coordination sphere arising by virtue of its flexibility in bonding. Modern experimental and computational methods allow the detection and study of previously unknown features of bonding between zinc and its ligands in protein environment. These discoveries are occurring just in time as novel biological functions of zinc, which involve rather unconventional coordination trends, are emerging. In this sense coordination sphere expansion of structural zinc sites, as observed in our previous experiments, is a novel phenomenon. Here we explore the electronic and structural requirements by simulating this phenomenon in structural zinc sites using DFT computations. For this purpose, we have chosen MPW1PW91 and a mixed basis set combination as the DFT method through benchmarking, because it accurately reproduces structural parameters of experimentally characterized zinc compounds. Using appropriate models, we show that the greater ionic character of zinc coordination would allow for coordination sphere expansion if the steric and electrostatic repulsions of the ligands are attenuated properly. Importantly, through the study of electronic and structural aspects of the models used, we arrive at a comprehensive bonding model, explaining the factors that influence coordination of zinc in proteins. The proposed model along with the existing knowledge would enhance our ability to predict zinc binding sites in proteins, which is today of growing importance given the predicted enormity of the zinc proteome.

  4. Delay coordinates: a sensitive indicator of nonlinear dynamics in single charged particle motion in magnetic reversals

    NASA Astrophysics Data System (ADS)

    Chapman, Sandra C.; Watkins, Nicholas W.

    1995-08-01

    The delay coordinate technique is examined as an indicator of the regime of particle dynamics for the system of single charged particle motion in magnetic reversals. Examples of numerically integrated trajectories in both static (zero electric field) and time dependent (corresponding nonzero induction electric field) simple models for magnetic reversals are considered. In the static case, the dynamics can in principle be directly classified by constructing Poincaré surfaces of section; here we demonstrate that whilst the Poincaré surface contains the relevant information to classify the dynamics, the corresponding delay coordinate plot can provide a far more sensitive indication of the onset of nonregular behaviour. In the case of nonperiodic time dependence considered here Poincaré plots cannot in general be constructed directly. Nevertheless, delay coordinate plots can still reveal details of the phase space portrait of the system, and here are shown to indicate whether segments of stochastic motion exist in a given trajectory. It is anticipated that the delay coordinate plot technique as realized here will be a valuable tool in characterizing the behaviour in large numbers of trajectories that are evolved in time-dependent systems, thereby giving us insight into the evolution of the distribution function as a whole, either in prescribed fields or in self-consistent numerical simulations.

  5. The Virtual Teacher (VT) Paradigm: Learning New Patterns of Interpersonal Coordination Using the Human Dynamic Clamp

    PubMed Central

    2015-01-01

    The Virtual Teacher paradigm, a version of the Human Dynamic Clamp (HDC), is introduced into studies of learning patterns of inter-personal coordination. Combining mathematical modeling and experimentation, we investigate how the HDC may be used as a Virtual Teacher (VT) to help humans co-produce and internalize new inter-personal coordination pattern(s). Human learners produced rhythmic finger movements whilst observing a computer-driven avatar, animated by dynamic equations stemming from the well-established Haken-Kelso-Bunz (1985) and Schöner-Kelso (1988) models of coordination. We demonstrate that the VT is successful in shifting the pattern co-produced by the VT-human system toward any value (Experiment 1) and that the VT can help humans learn unstable relative phasing patterns (Experiment 2). Using transfer entropy, we find that information flow from one partner to the other increases when VT-human coordination loses stability. This suggests that variable joint performance may actually facilitate interaction, and in the long run learning. VT appears to be a promising tool for exploring basic learning processes involved in social interaction, unraveling the dynamics of information flow between interacting partners, and providing possible rehabilitation opportunities. PMID:26569608

  6. Patterns of horse-rider coordination during endurance race: a dynamical system approach.

    PubMed

    Viry, Sylvain; Sleimen-Malkoun, Rita; Temprado, Jean-Jacques; Frances, Jean-Philippe; Berton, Eric; Laurent, Michel; Nicol, Caroline

    2013-01-01

    In riding, most biomechanical studies have focused on the description of the horse locomotion in unridden condition. In this study, we draw the prospect of how the basic principles established in inter-personal coordination by the theory of Coordination Dynamics may provide a conceptual and methodological framework for understanding the horse-rider coupling. The recent development of mobile technologies allows combined horse and rider recordings during long lasting natural events such as endurance races. Six international horse-rider dyads were thus recorded during a 120 km race by using two tri-axial accelerometers placed on the horses and riders, respectively. The analysis concentrated on their combined vertical displacements. The obtained shapes and angles of Lissajous plots together with values of relative phase between horse and rider displacements at lower reversal point allowed us to characterize four coordination patterns, reflecting the use of two riding techniques per horse's gait (trot and canter). The present study shows that the concepts, methods and tools of self-organizing dynamic system approach offer new directions for understanding horse-rider coordination. The identification of the horse-rider coupling patterns constitutes a firm basis to further study the coalition of multiple constraints that determine their emergence and their dynamics in endurance race.

  7. Patterns of Horse-Rider Coordination during Endurance Race: A Dynamical System Approach

    PubMed Central

    Viry, Sylvain; Sleimen-Malkoun, Rita; Temprado, Jean-Jacques; Frances, Jean-Philippe; Berton, Eric; Laurent, Michel; Nicol, Caroline

    2013-01-01

    In riding, most biomechanical studies have focused on the description of the horse locomotion in unridden condition. In this study, we draw the prospect of how the basic principles established in inter-personal coordination by the theory of Coordination Dynamics may provide a conceptual and methodological framework for understanding the horse-rider coupling. The recent development of mobile technologies allows combined horse and rider recordings during long lasting natural events such as endurance races. Six international horse-rider dyads were thus recorded during a 120 km race by using two tri-axial accelerometers placed on the horses and riders, respectively. The analysis concentrated on their combined vertical displacements. The obtained shapes and angles of Lissajous plots together with values of relative phase between horse and rider displacements at lower reversal point allowed us to characterize four coordination patterns, reflecting the use of two riding techniques per horse's gait (trot and canter). The present study shows that the concepts, methods and tools of self-organizing dynamic system approach offer new directions for understanding horse-rider coordination. The identification of the horse-rider coupling patterns constitutes a firm basis to further study the coalition of multiple constraints that determine their emergence and their dynamics in endurance race. PMID:23940788

  8. Path planning in multi-scale ocean flows: Coordination and dynamic obstacles

    NASA Astrophysics Data System (ADS)

    Lolla, T.; Haley, P. J., Jr.; Lermusiaux, P. F. J.

    2015-10-01

    As the concurrent use of multiple autonomous vehicles in ocean missions grows, systematic control for their coordinated operation is becoming a necessity. Many ocean vehicles, especially those used in longer-range missions, possess limited operating speeds and are thus sensitive to ocean currents. Yet, the effect of currents on their trajectories is ignored by many coordination techniques. To address this issue, we first derive a rigorous level-set methodology for distance-based coordination of vehicles operating in minimum time within strong and dynamic ocean currents. The new methodology integrates ocean modeling, time-optimal level-sets and optimization schemes to predict the ocean currents, the short-term reachability sets, and the optimal headings for the desired coordination. Schemes are developed for dynamic formation control, where multiple vehicles achieve and maintain a given geometric pattern as they carry out their missions. To do so, a new score function that is suitable for regular polygon formations is obtained. Secondly, we obtain an efficient, non-intrusive technique for level-set-based time-optimal path planning in the presence of moving obstacles. The results are time-optimal path forecasts that rigorously avoid moving obstacles and sustain the desired coordination. They are exemplified and investigated for a variety of simulated ocean flows. A wind-driven double-gyre flow is used to study time-optimal dynamic formation control. Currents exiting an idealized strait or estuary are employed to explore dynamic obstacle avoidance. Finally, results are analyzed for the complex geometry and multi-scale ocean flows of the Philippine Archipelago.

  9. GPS coordinate time series measurements in Ontario and Quebec, Canada

    NASA Astrophysics Data System (ADS)

    Samadi Alinia, Hadis; Tiampo, Kristy F.; James, Thomas S.

    2017-01-01

    New precise network solutions for continuous GPS (cGPS) stations distributed in eastern Ontario and western Québec provide constraints on the regional three-dimensional crustal velocity field. Five years of continuous observations at fourteen cGPS sites were analyzed using Bernese GPS processing software. Several different sub-networks were chosen from these stations, and the data were processed and compared to in order to select the optimal configuration to accurately estimate the vertical and horizontal station velocities and minimize the associated errors. The coordinate time series were then compared to the crustal motions from global solutions and the optimized solution is presented here. A noise analysis model with power-law and white noise, which best describes the noise characteristics of all three components, was employed for the GPS time series analysis. The linear trend, associated uncertainties, and the spectral index of the power-law noise were calculated using a maximum likelihood estimation approach. The residual horizontal velocities, after removal of rigid plate motion, have a magnitude consistent with expected glacial isostatic adjustment (GIA). The vertical velocities increase from subsidence of almost 1.9 mm/year south of the Great Lakes to uplift near Hudson Bay, where the highest rate is approximately 10.9 mm/year. The residual horizontal velocities range from approximately 0.5 mm/year, oriented south-southeastward, at the Great Lakes to nearly 1.5 mm/year directed toward the interior of Hudson Bay at stations adjacent to its shoreline. Here, the velocity uncertainties are estimated at less than 0.6 mm/year for the horizontal component and 1.1 mm/year for the vertical component. A comparison between the observed velocities and GIA model predictions, for a limited range of Earth models, shows a better fit to the observations for the Earth model with the smallest upper mantle viscosity and the largest lower mantle viscosity. However, the

  10. Energetic ion dynamics of the inner magnetosphere revealed in coordinated Cluster-Double Star observations

    NASA Astrophysics Data System (ADS)

    Dandouras, Iannis; Cao, Jinbin; Vallat, Claire

    2009-01-01

    Since early 2004 the Chinese spacecraft Tan Ce 1 (TC-1), first component of the Double Star (DSP) mission, has been on an equatorial elliptical orbit (13.4 R E apogee), allowing the study of the dynamics of the Earth's magnetosphere in conjunction with the four European Cluster spacecraft (19.6 R E apogee). The Cluster and Double Star spacecraft orbits are such that the spacecraft are almost in the same meridian, allowing conjugate studies. The four Cluster spacecraft highly eccentric polar orbit at 4 R E perigee permits them to sample the ring current, the radiation belts, and the outer plasmasphere from south to north, almost following the same magnetic flux tube (latitudinal profile), whereas TC-1, with its very low-perigee equatorial orbit, gives the plasma profile across L shells. Coordinated ion measurements provided by the Cluster Ion Spectrometry and Hot Ion Analyzer instruments onboard Cluster and TC-1, respectively, obtained during quiet conditions, disturbed geomagnetic conditions, and an intense storm, are used to analyze crossings of the plasmasphere and the ring current region. Multiple narrow ion energy bands (``nose-like'' structures) are simultaneously observed by both Cluster and TC-1. These observations reveal the large-scale character of these structures and pose a challenge for the simulation and modeling of the inner magnetosphere populations.

  11. Switching among graphic patterns is governed by oscillatory coordination dynamics: implications for understanding handwriting.

    PubMed

    Zanone, Pier-Giorgio; Athènes, Sylvie

    2013-01-01

    Revisiting an original idea by Hollerbach (1981), previous work has established that the production of graphic shapes, assumed to be the blueprint for handwriting, is governed by the dynamics of orthogonal non-linear coupled oscillators. Such dynamics determines few stable coordination patterns, giving rise to a limited set of preferred graphic shapes, namely, four lines and four ellipsoids independent of orientation. The present study investigates the rules of switching among such graphic coordination patterns. Seven participants were required to voluntarily switch within twelve pairs of shapes presented on a graphic tablet. In line with previous theoretical and experimental work on bimanual coordination, results corroborated our hypothesis that the relative stability of the produced coordination patterns determines the time needed for switching: the transition to a more stable pattern was shorter, and inversely. Moreover, switching between patterns with the same orientation but different eccentricities was faster than with a change in orientation. Nonetheless, the switching time covaried strictly with the change in relative phase effected by the transition between two shapes, whether this implied a change in eccentricity or in orientation. These findings suggest a new operational definition of what the (motor) units or strokes of handwriting are and shed a novel light on how coarticulation and recruitment of degrees of freedom may occur in graphic skills. They also yield some leads for understanding the acquisition and the neural underpinnings of handwriting.

  12. Sensor Prototype to Evaluate the Contact Force in Measuring with Coordinate Measuring Arms

    PubMed Central

    Cuesta, Eduardo; Telenti, Alejandro; Patiño, Hector; González-Madruga, Daniel; Martínez-Pellitero, Susana

    2015-01-01

    This paper describes the design, development and evaluation tests of an integrated force sensor prototype for portable Coordinate Measuring Arms (CMAs or AACMMs). The development is based on the use of strain gauges located on the surface of the CMAs’ hard probe. The strain gauges as well as their cables and connectors have been protected with a custom case, made by Additive Manufacturing techniques (Polyjet 3D). The same method has been selected to manufacture an ergonomic handle that includes trigger mechanics and the electronic components required for synchronizing the trigger signal when probing occurs. The paper also describes the monitoring software that reads the signals in real time, the calibration procedure of the prototype and the validation tests oriented towards increasing knowledge of the forces employed in manual probing. Several experiments read and record the force in real time comparing different ways of probing (discontinuous and continuous contact) and measuring different types of geometric features, from single planes to exterior cylinders, cones, or spheres, through interior features. The probing force is separated into two components allowing the influence of these strategies in probe deformation to be known. The final goal of this research is to improve the probing technique, for example by using an operator training programme, allowing extra-force peaks and bad contacts to be minimized or just to avoid bad measurements. PMID:26057038

  13. Coordination of Flow and Traction in Migration of Amoeboid Physarum polycephalum: Model and Measurement

    NASA Astrophysics Data System (ADS)

    Lewis, Owen; Guy, Robert; Zhang, Shun; Del Alamo, Juan Carlos

    2014-11-01

    In this research, we develop a computational model of crawling Physarum based on the Immersed Boundary Method. Our model incorporates the effects of cell cytoplasm, the internal cytoskeleton and adhesions to the substrate. Cytoplasmic flows and traction stresses predicted by the model are compared to experimentally measured values obtained using simultaneous Traction Force Microscopy (TFM) and Particle Image Velocimetry (PIV). Of particular interest are stresses generated by flow and how transmission of stresses to the substrate is coordinated. We identify methods of adhesion-flow coordination which are consistent with experiments. Certain consisten coordinations are seen to be ``optimal'' with regards to crawling speed, and robust to perturbations in the extracellular environment.

  14. Hybrid probing technique for coordinate measurement with optically trapped micro sphere

    NASA Astrophysics Data System (ADS)

    Yamaguchi, Yuki; Michihata, Masaki; Mizutani, Yasuhiro; Takaya, Yasuhiro

    2016-11-01

    Engineered surfaces have been fabricated to provide enhanced properties such as low friction, anti-adhesive behavior, or low reflection of light. At micro-scales, surface force highly affects the functionality of mechanical parts. In order to reduce surface force such as friction, micro mechanical parts that have engineered surfaces are demanded. In order to investigate the functionality of the textured micro parts, it is necessary to evaluate both the three-dimensional shape and the surface topography along with its geometry. Then we propose novel hybrid probing technique using an optically trapped micro sphere. Tightly focused laser beam makes it possible for a dielectric micro sphere to sustain near the focal point in the air. The dynamic behavior of the micro sphere changes as the result of the interaction of the surface. Therefore, the surface is detected by monitoring the micro sphere. This enables the three-dimensional shape measurement of the substrate. On the other hand, Surface topography is imaged with the lensing effect of the trapped micro sphere. Therefore, this trapped sphere is used as both a probe for coordinate metrology and a micro-lens in optical microscopy in this study. This present investigation deals with the development and fundamental validation of the hybrid probing system with the optically trapped micro sphere. The measurement result with high performance was demonstrated using the tilted diffraction grating.

  15. Asymmetry of foot position and weight distribution channels the inter-leg coordination dynamics of standing.

    PubMed

    Wang, Zheng; Newell, Karl M

    2012-10-01

    The study of quiet standing has mainly been conducted in the foot side-by-side position with the assumption that the contribution of the lower limbs is structurally and functionally equivalent. The purpose of this study was to examine how the two mechanical factors of foot position and weight distribution interact to influence postural control and inter-leg coordination dynamics. Participants were required, while standing in either a side-by-side, staggered, or tandem right foot forward position, to intentionally produce three different levels of weight distribution (50/50, 30/70, and 70/30) over the two feet. Our results showed that the interaction effects of the two mechanical constraints were represented in both linear and nonlinear analyses. The center of pressure (COP) mean velocity was predominantly influenced by body weight distribution in the side-by-side stance, whereas foot position was more influential in the tandem stance. The nonlinear analysis showed that the least experienced postural condition (i.e., tandem stance with a 70/30 loading level) had the lowest number and total duration of COP(L)-COP(R) phase synchronization epochs in the AP direction that were compensated by "stable" coordination dynamics in the ML direction. The findings revealed that the staggered stance represents a "hybrid" blend of the properties of the side-by-side and tandem foot positions. Collectively, foot position and weight distribution interact to determine the stability and flexibility of inter-leg coordination dynamics in postural control.

  16. A practical coordinate unification method for integrated tactile-optical measuring system

    NASA Astrophysics Data System (ADS)

    Li, Feng; Peter Longstaff, Andrew; Fletcher, Simon; Myers, Alan

    2014-04-01

    To meet the requirement of both high speed and high accuracy 3D measurements for dimensional metrology, multi-sensor measuring systems have been developed to measure, analyse and reverse engineer the geometry of objects. This paper presents a new development in coordinate unification called the "centroid of spherical centres" method, which can be used instead of the traditional method which uses three datum-points to perform the geometric transformation and unification of tactile and optical sensors. The benefits of the proposed method are improved accuracy in coordinate unification and the method is used to integrate a coordinate measuring machine (CMM) and optical sensors (structured light scanning system and FaroArm laser line probe). A sphere-plate artefact is developed for data fusion of the multi-sensor system and experimental results validate the accuracy and effectiveness of this method.

  17. Research on performance evaluation of non-arm coordinate measuring machine (NACMM)

    NASA Astrophysics Data System (ADS)

    Wang, Weinong; Wei, Hengzheng; Xia, Yang

    2010-11-01

    The methods for performance evaluation of Articulated Arm Coordinate Measuring Machine (AACMM) have been published. Non-arm Coordinate Measuring Machine (NACMM) is similar with AACMM in function, and then the performance evaluation methods should be also similar. The research based on comparing the principle and error resources of the both systems, set up a new combination of the position, orientation and test number, try to locate a more reasonable procedure in evaluate the performance of NACMMs which can be comparable with ASME B89.4.22-2004, but better for find the characteristic of accuracy changing in measurement volume. The procedure is confirmed by testing of different NACMMs.

  18. Some Results of Coordinate Measurements of Local Radio Sources on the Sun.

    DTIC Science & Technology

    1977-10-03

    7 AD-A VS@ 186 SOME RESULTS OF COORDINATE MEASUREMENTS OF LOCAL RADIO iSOURCES ON THE SUN (U) NAVRL OCEAN SYSTEMS CENTER SRN1) DIEGO CR Y N BOROYIK ET...MEASUREMENTS OF LOCAL RADIO !C~i SOURCES ON THE SUN ell Translated by CM Bigger from an article by VN Borovik and AV Temirova Edited by MP Bleiweiss C...COORDINATE MEASUREMENTS OF LOCAL RADIO SOURCES ON THE SUN 12 PERSOML AJT"ORS V.N. Borovik, A.V. Temirova 1l W 0 REPORT l3b VM COVIRED 4 SAlE 09 9504 f . 4 j

  19. Coordinate measurement of hidden parts using an attitude angle sensor and a laser rangefinder

    NASA Astrophysics Data System (ADS)

    Fan, Yiyan; Zhao, Bin

    2014-12-01

    A noncontacting combined measuring system comprising a nondiffracting beam attitude angle sensor, laser rangefinder, and total station is proposed for the coordinate measurement of hidden parts in large-scale spaces. The laser from the total station is aimed at the retro-reflector of the attitude angle sensor to obtain the spatial coordinates. Moreover, parts of the laser pass through the retro-reflector and generate a nondiffracting beam spot on the charge-coupled diode through an axicon lens. The horizontal angle of the attitude angle sensor can be obtained by using center fitting of the nondiffracting beam spot. An inclinometer can be used to obtain the rolling angle and the pitching angle. The laser from the rangefinder is directed at the measured point to measure the distance from the attitude angle sensor to the measured point. Finally, the spatial coordinates of the measured point can be calculated by using the measured spatial coordinates, the three attitude angles, and the distance. The experimental results of the combined measuring system are compared with those of the total station. The two results show good agreement.

  20. 'Dynamic Distance' Reaction Coordinate for Competing Bonds:  Applications in Classical and Ab Initio Simulations.

    PubMed

    Burisch, Christian; Markwick, Phineus R L; Doltsinis, Nikos L; Schlitter, Jürgen

    2008-01-01

    A versatile reaction coordinate, the "dynamic distance", is introduced for the study of reactions involving the rupture and formation of a series of chemical bonds or contacts. The dynamic distance is a mass-weighted mean of selected distances. When implemented as a generalized constraint, the dynamic distance is particularly suited for driving activated processes by controlled increase during a simulation. As a single constraint acting upon multiple degrees of freedom, the sequence of events along the resulting reaction pathway is determined unambiguously by the underlying energy landscape. Free energy profiles can be readily obtained from the mean constraint force. In this paper both theoretical aspects and numerical implementation are discussed, and the unique and diverse properties of this reaction coordinate are demonstrated using three examples:  In the framework of Car-Parrinello molecular dynamics, we present results for the prototypical double proton-transfer reaction in formic acid dimer and the photocycle of the guanine-cytosine DNA base pair. As a classical mechanical example, the opening of the binding pocket of the enzyme rubisco is analyzed.

  1. Effects of Agent-Environment Symmetry on the Coordination Dynamics of Triadic Jumping.

    PubMed

    Kijima, Akifumi; Shima, Hiroyuki; Okumura, Motoki; Yamamoto, Yuji; Richardson, Michael J

    2017-01-01

    We investigated whether the patterns of coordination that emerged during a three-participant (triadic) jumping task were defined by the symmetries of the (multi) agent-environment task space. Triads were instructed to jump around different geometrical arrangements of hoops. The symmetry of the hoop geometry was manipulated to create two symmetrical and two asymmetrical participant-hoop configurations. Video and motion tracking recordings were employed to determine the frequencies of coordination misses (collisions or failed jumps) and during 20 successful jump sequences, the jump direction chosen (clockwise vs. counterclockwise) and the patterning of between participant temporal movement lags within and across jump events. The results revealed that the (a)symmetry of the joint action workspace significantly influenced the (a)symmetry of the jump direction dynamics and, more importantly, the (a)symmetry of the between participant coordination lags. The symmetrical participant-hoop configurations resulted in smaller overall movement lags and a more spontaneous, interchangeable leader/follower relationship between participants, whereas the asymmetrical participant-hoop configurations resulted in slightly larger overall movements lags and a more explicit, persistent asymmetry in the leader/follower relationship of participants. The degree to which the patterns of behavioral coordination that emerged were consistent with the theory of symmetry groups and spontaneous and explicit symmetry-breaking are discussed.

  2. Shared knowledge or shared affordances? Insights from an ecological dynamics approach to team coordination in sports.

    PubMed

    Silva, Pedro; Garganta, Júlio; Araújo, Duarte; Davids, Keith; Aguiar, Paulo

    2013-09-01

    Previous research has proposed that team coordination is based on shared knowledge of the performance context, responsible for linking teammates' mental representations for collective, internalized action solutions. However, this representational approach raises many questions including: how do individual schemata of team members become reformulated together? How much time does it take for this collective cognitive process to occur? How do different cues perceived by different individuals sustain a general shared mental representation? This representational approach is challenged by an ecological dynamics perspective of shared knowledge in team coordination. We argue that the traditional shared knowledge assumption is predicated on 'knowledge about' the environment, which can be used to share knowledge and influence intentions of others prior to competition. Rather, during competitive performance, the control of action by perceiving surrounding informational constraints is expressed in 'knowledge of' the environment. This crucial distinction emphasizes perception of shared affordances (for others and of others) as the main communication channel between team members during team coordination tasks. From this perspective, the emergence of coordinated behaviours in sports teams is based on the formation of interpersonal synergies between players resulting from collective actions predicated on shared affordances.

  3. Effects of Agent-Environment Symmetry on the Coordination Dynamics of Triadic Jumping

    PubMed Central

    Kijima, Akifumi; Shima, Hiroyuki; Okumura, Motoki; Yamamoto, Yuji; Richardson, Michael J.

    2017-01-01

    We investigated whether the patterns of coordination that emerged during a three-participant (triadic) jumping task were defined by the symmetries of the (multi) agent-environment task space. Triads were instructed to jump around different geometrical arrangements of hoops. The symmetry of the hoop geometry was manipulated to create two symmetrical and two asymmetrical participant-hoop configurations. Video and motion tracking recordings were employed to determine the frequencies of coordination misses (collisions or failed jumps) and during 20 successful jump sequences, the jump direction chosen (clockwise vs. counterclockwise) and the patterning of between participant temporal movement lags within and across jump events. The results revealed that the (a)symmetry of the joint action workspace significantly influenced the (a)symmetry of the jump direction dynamics and, more importantly, the (a)symmetry of the between participant coordination lags. The symmetrical participant-hoop configurations resulted in smaller overall movement lags and a more spontaneous, interchangeable leader/follower relationship between participants, whereas the asymmetrical participant-hoop configurations resulted in slightly larger overall movements lags and a more explicit, persistent asymmetry in the leader/follower relationship of participants. The degree to which the patterns of behavioral coordination that emerged were consistent with the theory of symmetry groups and spontaneous and explicit symmetry-breaking are discussed. PMID:28210231

  4. Coordination, Organisation and Model-driven Approaches for Dynamic, Flexible, Robust Software and Services Engineering

    NASA Astrophysics Data System (ADS)

    Nieves, Juan Carlos; Padget, Julian; Vasconcelos, Wamberto; Staikopoulos, Athanasios; Cliffe, Owen; Dignum, Frank; Vázquez-Salceda, Javier; Clarke, Siobhán; Reed, Chris

    Enterprise systems are increasingly composed of (and even functioning as) components in a dynamic, digital ecosystem. On the one hand, this new situation requires flexible, spontaneous and opportunistic collaboration activities to be identified and established among (electronic) business parties. On the other, it demands engineering methods that are able to integrate new functionalities and behaviours into running systems composed by active, distributed, interdependent processes. Here we present a multi-level architecture that combines organisational and coordination theories with model driven development, for the implementation, deployment and management of dynamic, flexible and robust service-oriented business applications, combined with a service layer that accommodates semantic service description, fine-grained semantic service discovery and the dynamic adaptation of services to meet changing circumstances.

  5. Minimization of deviations of gear real tooth surfaces determined by coordinate measurements

    NASA Technical Reports Server (NTRS)

    Litvin, F. L.; Kuan, C.; Wang, J.-C.; Handschuh, R. F.; Masseth, J.; Maruyama, N.

    1992-01-01

    The deviations of a gear's real tooth surface from the theoretical surface are determined by coordinate measurements at the grid of the surface. A method was developed to transform the deviations from Cartesian coordinates to those along the normal at the measurement locations. Equations are derived that relate the first order deviations with the adjustment to the manufacturing machine-tool settings. The deviations of the entire surface are minimized. The minimization is achieved by application of the least-square method for an overdetermined system of linear equations. The proposed method is illustrated with a numerical example for hypoid gear and pinion.

  6. Traffic Management Coordinator Evaluation of the Dynamic Weather Routes Concept and System

    NASA Technical Reports Server (NTRS)

    Gong, Chester

    2014-01-01

    Dynamic Weather Routes (DWR) is a weather-avoidance system for airline dispatchers and FAA traffic managers that continually searches for and advises the user of more efficient routes around convective weather. NASA and American Airlines (AA) have been conducting an operational trial of DWR since July 17, 2012. The objective of this evaluation is to assess DWR from a traffic management coordinator (TMC) perspective, using recently retired TMCs and actual DWR reroutes advisories that were rated acceptable by AA during the operational trial. Results from the evaluation showed that the primary reasons for a TMC to modify or reject airline reroute requests were related to airspace configuration. Approximately 80 percent of the reroutes evaluated required some coordination before implementation. Analysis showed TMCs approved 62 percent of the requested DWR reroutes, resulting in 57 percent of the total requested DWR time savings.

  7. The method design of coordinates mapping in PIV measurement system for flow field of impinging streams

    NASA Astrophysics Data System (ADS)

    Li, Fubao; Wang, Dexi; Li, Qin

    2009-12-01

    In the Particle Image Velocimetry (PIV) measurement system for flow field of impinging streams, in order to realize the calculation of real flow field data from sequence image, the method of coordinates mapping applying neural network is designed. This method is to put a plat with normal pitch grid in the area of transparent Liquid-continuous impinging streams reactor, with the grid plan going through the cylinder axis of the reactor filled with water. Digital camera is fixed outside the container, with the light axis vertical to the grid plan. Software tool is utilized to obtain Educate vector collect for educating neural network. The network which finished training can counterchange the pixel coordinate of the measured plan in the liquid into real coordinate.

  8. The method design of coordinates mapping in PIV measurement system for flow field of impinging streams

    NASA Astrophysics Data System (ADS)

    Li, Fubao; Wang, Dexi; Li, Qin

    2010-01-01

    In the Particle Image Velocimetry (PIV) measurement system for flow field of impinging streams, in order to realize the calculation of real flow field data from sequence image, the method of coordinates mapping applying neural network is designed. This method is to put a plat with normal pitch grid in the area of transparent Liquid-continuous impinging streams reactor, with the grid plan going through the cylinder axis of the reactor filled with water. Digital camera is fixed outside the container, with the light axis vertical to the grid plan. Software tool is utilized to obtain Educate vector collect for educating neural network. The network which finished training can counterchange the pixel coordinate of the measured plan in the liquid into real coordinate.

  9. Dynamic temperature measurements with embedded optical sensors.

    SciTech Connect

    Dolan, Daniel H.,; Seagle, Christopher T; Ao, Tommy

    2013-10-01

    This report summarizes LDRD project number 151365, \\Dynamic Temperature Measurements with Embedded Optical Sensors". The purpose of this project was to develop an optical sensor capable of detecting modest temperature states (<1000 K) with nanosecond time resolution, a recurring diagnostic need in dynamic compression experiments at the Sandia Z machine. Gold sensors were selected because the visible re ectance spectrum of gold varies strongly with temperature. A variety of static and dynamic measurements were performed to assess re ectance changes at di erent temperatures and pressures. Using a minimal optical model for gold, a plausible connection between static calibrations and dynamic measurements was found. With re nements to the model and diagnostic upgrades, embedded gold sensors seem capable of detecting minor (<50 K) temperature changes under dynamic compression.

  10. Perspective: Insight into reaction coordinates and dynamics from the potential energy landscape

    SciTech Connect

    Wales, D. J.

    2015-04-07

    This perspective focuses on conceptual and computational aspects of the potential energy landscape framework. It has two objectives: first to summarise some key developments of the approach and second to illustrate how such techniques can be applied using a specific example that exploits knowledge of pathways. Recent developments in theory and simulation within the landscape framework are first outlined, including methods for structure prediction, analysis of global thermodynamic properties, and treatment of rare event dynamics. We then develop a connection between the kinetic transition network treatment of dynamics and a potential of mean force defined by a reaction coordinate. The effect of projection from the full configuration space to low dimensionality is illustrated for an atomic cluster. In this example, where a relatively successful structural order parameter is available, the principal change in cluster morphology is reproduced, but some details are not faithfully represented. In contrast, a profile based on configurations that correspond to the discrete path defined geometrically retains all the barriers and minima. This comparison provides insight into the physical origins of “friction” effects in low-dimensionality descriptions of dynamics based upon a reaction coordinate.

  11. Impact loading and locomotor-respiratory coordination significantly influence breathing dynamics in running humans.

    PubMed

    Daley, Monica A; Bramble, Dennis M; Carrier, David R

    2013-01-01

    Locomotor-respiratory coupling (LRC), phase-locking between breathing and stepping rhythms, occurs in many vertebrates. When quadrupedal mammals gallop, 1∶1 stride per breath coupling is necessitated by pronounced mechanical interactions between locomotion and ventilation. Humans show more flexibility in breathing patterns during locomotion, using LRC ratios of 2∶1, 2.5∶1, 3∶1, or 4∶1 and sometimes no coupling. Previous studies provide conflicting evidence on the mechanical significance of LRC in running humans. Some studies suggest LRC improves breathing efficiency, but others suggest LRC is mechanically insignificant because 'step-driven flows' (ventilatory flows attributable to step-induced forces) contribute a negligible fraction of tidal volume. Yet, although step-driven flows are brief, they cause large fluctuations in ventilatory flow. Here we test the hypothesis that running humans use LRC to minimize antagonistic effects of step-driven flows on breathing. We measured locomotor-ventilatory dynamics in 14 subjects running at a self-selected speed (2.6±0.1 ms(-1)) and compared breathing dynamics in their naturally 'preferred' and 'avoided' entrainment patterns. Step-driven flows occurred at 1-2X step frequency with peak magnitudes of 0.97±0.45 Ls(-1) (mean ±S.D). Step-driven flows varied depending on ventilatory state (high versus low lung volume), suggesting state-dependent changes in compliance and damping of thoraco-abdominal tissues. Subjects naturally preferred LRC patterns that minimized antagonistic interactions and aligned ventilatory transitions with assistive phases of the step. Ventilatory transitions initiated in 'preferred' phases within the step cycle occurred 2x faster than those in 'avoided' phases. We hypothesize that humans coordinate breathing and locomotion to minimize antagonistic loading of respiratory muscles, reduce work of breathing and minimize rate of fatigue. Future work could address the potential consequences of

  12. Measurements of glottal structure dynamics

    NASA Astrophysics Data System (ADS)

    Holzrichter, John F.; Ng, Lawrence C.; Burke, Gerry J.; Champagne, Nathan J.; Kallman, Jeffrey S.; Sharpe, Robert M.; Kobler, James B.; Hillman, Robert E.; Rosowski, John J.

    2005-03-01

    Low power, radarlike electromagnetic (EM) wave sensors, operating in a homodyne interferometric mode, are being used to measure tissue motions in the human vocal tract during speech. However, when these and similar sensors are used in front of the laryngeal region during voiced speech, there remains an uncertainty regarding the contributions to the sensor signal from vocal fold movements versus those from pressure induced trachea-wall movements. Several signal-source hypotheses are tested by performing experiments with a subject who had undergone tracheostomy, and who still was able to phonate when her stoma was covered (e.g., with a plastic plate). Laser-doppler motion-measurements of the subject's posterior trachea show small tissue movements, about 15 microns, that do not contribute significantly to signals from presently used EM sensors. However, signals from the anterior wall do contribute. EM sensor and air-pressure measurements, together with 3-D EM wave simulations, show that EM sensors measure movements of the vocal folds very well. The simulations show a surprisingly effective guiding of EM waves across the vocal fold membrane, which, upon glottal opening, are interrupted and reflected. These measurements are important for EM sensor applications to speech signal de-noising, vocoding, speech recognition, and diagnostics. .

  13. Dynamic contact angle measurements on superhydrophobic surfaces

    NASA Astrophysics Data System (ADS)

    Kim, Jeong-Hyun; Kavehpour, H. Pirouz; Rothstein, Jonathan P.

    2015-03-01

    In this paper, the dynamic advancing and receding contact angles of a series of aqueous solutions were measured on a number of hydrophobic and superhydrophobic surfaces using a modified Wilhelmy plate technique. Superhydrophobic surfaces are hydrophobic surfaces with micron or nanometer sized surface roughness. These surfaces have very large static advancing contact angles and little static contact angle hysteresis. In this study, the dynamic advancing and dynamic receding contact angles on superhydrophobic surfaces were measured as a function of plate velocity and capillary number. The dynamic contact angles measured on a smooth hydrophobic Teflon surface were found to obey the scaling with capillary number predicted by the Cox-Voinov-Tanner law, θD3 ∝ Ca. The response of the dynamic contact angle on the superhydrophobic surfaces, however, did not follow the same scaling law. The advancing contact angle was found to remain constant at θA = 160∘, independent of capillary number. The dynamic receding contact angle measurements on superhydrophobic surfaces were found to decrease with increasing capillary number; however, the presence of slip on the superhydrophobic surface was found to result in a shift in the onset of dynamic contact angle variation to larger capillary numbers. In addition, a much weaker dependence of the dynamic contact angle on capillary number was observed for some of the superhydrophobic surfaces tested.

  14. Mass properties measurement system: Dynamics and statics measurements

    NASA Technical Reports Server (NTRS)

    Doty, Keith L.

    1993-01-01

    This report presents and interprets experimental data obtained from the Mass Properties Measurement System (MPMS). Statics measurements yield the center-of-gravity of an unknown mass and dynamics measurements yield its inertia matrix. Observations of the MPMS performance has lead us to specific design criteria and an understanding of MPMS limitations.

  15. Tortoise Coordinates and Hawking Radiation in a Dynamical Spherically Symmetric Spacetime

    NASA Astrophysics Data System (ADS)

    Yang, Jian; Zhao, Zheng; Tian, Gui-Hua; Liu, Wen-Biao

    2009-12-01

    Hawking effect from dynamical spherical Vaidya black hole, Vaidya-Bonner black hole, and Vaidya-de Sitter black hole is investigated using the improved Damour-Ruffini method. After the new tortoise coordinate transformation in which the position r of event horizon is an undetermined function and the temperature parameter κ is an undetermined constant, the Klein-Gordon equation can be written as the standard form at the event horizon, and both r and κ can be determined automatically. Then extending the outgoing wave from outside to inside of the horizon analytically, the Hawking temperature can also be obtained automatically.

  16. Selective Adsorption of CO2 from Light Gas Mixtures Using a Structurally Dynamic Porous Coordination Polymer**

    SciTech Connect

    Kristi L. Kauffman, Jeffrey T. Culp, Andrew J. Allen, Laura Espinal, Winnie Wong-Ng, Thomas D. Brown, Angela Goodman, Mark P. Bernardo, Russel J. Pancoast, Danielle Chirdon, Christopher Matranga*

    2010-01-01

    The selective adsorption of CO{sub 2} from mixtures with N{sub 2}, CH{sub 4}, and N{sub 2}O in a dynamic porous coordination polymer (see monomer structure) was evaluated by ATR-FTIR spectroscopy, GC, and SANS. All three techniques indicate highly selective adsorption of CO{sub 2} from CO{sub 2}/CH{sub 4} and CO{sub 2}/N{sub 2} mixtures at 30 C, with no selectivity observed for the CO{sub 2}/N{sub 2}O system.

  17. Efficient and direct generation of multidimensional free energy surfaces via adiabatic dynamics without coordinate transformations.

    PubMed

    Abrams, Jerry B; Tuckerman, Mark E

    2008-12-11

    Adiabatic free energy dynamics (AFED) was introduced by Rosso et al. [J. Chem. Phys. 2002, 116, 4389] for computing free energy profiles quickly and accurately using a dynamical adiabatic separation between a set of collective variables or reaction coordinates and the remaining degrees of freedom of a system. This approach has been shown to lead to a significant gain in efficiency versus traditional methods such as umbrella sampling, thermodynamic integration, and free energy perturbation for generating one-dimensional free energy profiles. More importantly, AFED is able to generate multidimensional free energy surfaces efficiently via full sweeps of the surface that rapidly map out the locations of the free energy minima. The most significant drawback to the AFED approach is the need to transform the coordinates into a generalized coordinate system that explicitly contains the collective variables of interest. Recently, Maragliano and Vanden-Eijnden built upon the AFED approach by introducing a set of extended phase-space variables, to which the adiabatic decoupling and high temperature are applied [Chem. Phys. Lett. 2006, 426, 168]. In this scheme, which the authors termed "temperature accelerated molecular dynamics" or TAMD, the need for explicit coordinate transformations is circumvented. The ability of AFED and TAMD to generate free energy surfaces efficiently depends on the thermostatting mechanism employed, since both approaches are inherently nonequilibrium due to the adiabatic decoupling. Indeed, Maragliano and Vanden-Eijnden did not report any direct generation of free energy surfaces within the overdamped Langevin dynamics employed by these authors. Here, we show that by formulating TAMD in a manner that is closer to the original AFED approach, including the generalized Gaussian moment thermostat (GGMT) and multiple time-scale integration, multidimensional free energy surfaces for complex systems can be generated directly from the probability

  18. Dynamic Force Measurement with Strain Gauges

    ERIC Educational Resources Information Center

    Lee, Bruce E.

    1974-01-01

    Discusses the use of four strain gauges, a Wheatstone bridge, and an oscilloscope to measure forces dynamically. Included is an example of determining the centripetal force of a pendulum in a general physics laboratory. (CC)

  19. A dynamic compressometer for converse electrostriction measurements

    NASA Astrophysics Data System (ADS)

    Yimnirun, Rattikorn; Moses, Paul J.; Newnham, Robert E.; Meyer, Richard J.

    2003-07-01

    A simple dynamic instrument for measuring very small stress dependence of capacitance is presented in this article. We describe the design and development of a dynamic compressometer for converse electrostrictive measurements on low dielectric constant materials. This redesigned system is capable of resolving a change in capacitance of 10-17 F or smaller. The most important feature is the dynamic stressing system incorporated to improve the accuracy and the reproducibility of the measurements. Furthermore, the uniaxiality and uniformity of the applied stress are found to be critical to the measurements. Therefore, a uniaxial stress delivery scheme using ball bearings is employed in the measurements to improve the accuracy of the experimental results. The converse electrostrictive coefficients obtained from this instrument agree reasonably well with those measured directly by a single-beam interferometer.

  20. Research on large spatial coordinate automatic measuring system based on multilateral method

    NASA Astrophysics Data System (ADS)

    Miao, Dongjing; Li, Jianshuan; Li, Lianfu; Jiang, Yuanlin; Kang, Yao; He, Mingzhao; Deng, Xiangrui

    2015-10-01

    To measure the spatial coordinate accurately and efficiently in large size range, a manipulator automatic measurement system which based on multilateral method is developed. This system is divided into two parts: The coordinate measurement subsystem is consists of four laser tracers, and the trajectory generation subsystem is composed by a manipulator and a rail. To ensure that there is no laser beam break during the measurement process, an optimization function is constructed by using the vectors between the laser tracers measuring center and the cat's eye reflector measuring center, then an orientation automatically adjust algorithm for the reflector is proposed, with this algorithm, the laser tracers are always been able to track the reflector during the entire measurement process. Finally, the proposed algorithm is validated by taking the calibration of laser tracker for instance: the actual experiment is conducted in 5m × 3m × 3.2m range, the algorithm is used to plan the orientations of the reflector corresponding to the given 24 points automatically. After improving orientations of some minority points with adverse angles, the final results are used to control the manipulator's motion. During the actual movement, there are no beam break occurs. The result shows that the proposed algorithm help the developed system to measure the spatial coordinates over a large range with efficiency.

  1. Mobile large scale 3D coordinate measuring system based on network of rotating laser automatic theodolites

    NASA Astrophysics Data System (ADS)

    Liu, Zhigang; Liu, Zhongzheng; Wu, Jianwei; Xu, Yaozhong

    2010-08-01

    This paper presents a mobile 3D coordinate measuring system for large scale metrology. This system is composed of a network of rotating laser automatic theodolites (N-RLATs) and a portable touch probe. In the N-RLAT system, each RLAT consists of two laser fans which rotate about its own Z axis at a constant speed and scan the whole metrology space. The optical sensors mounted on the portable touch probe receive the sweeping laser fans and generate the corresponding pulse signals, which establish a relationship between rotating angle of laser fan and time, and then the space angle measurement is converted into the corresponding peak time precision measurement of pulse signal. The rotating laser fans are modeled mathematically as a time varying parametrical vector in its local framework. A two steps on-site calibration method for solving the parameters of each RLAT and coordinate transformation among the N-RLATs. The portable probe is composed of optical sensors array with specified geometrical features and a touch point, on which the coordinates of optical sensors is determined by the N-RLATs and the touch point is estimated by solving a non-linear system. A prototype mobile 3D coordinate measuring system is developed and experiment results show its validity.

  2. Control of hierarchical polymer mechanics with bioinspired metal-coordination dynamics

    PubMed Central

    Grindy, Scott C.; Learsch, Robert; Mozhdehi, Davoud; Cheng, Jing; Barrett, Devin G.; Guan, Zhibin; Messersmith, Phillip B.; Holten-Andersen, Niels

    2015-01-01

    In conventional polymer materials, mechanical performance is traditionally engineered via material structure, using motifs such as polymer molecular weight, polymer branching, or copolymer-block design1. Here, by means of a model system of 4-arm poly(ethylene glycol) hydrogels crosslinked with multiple, kinetically distinct dynamic metal-ligand coordinate complexes, we show that polymer materials with decoupled spatial structure and mechanical performance can be designed. By tuning the relative concentration of two types of metal-ligand crosslinks, we demonstrate control over the material’s mechanical hierarchy of energy-dissipating modes under dynamic mechanical loading, and therefore the ability to engineer a priori the viscoelastic properties of these materials by controlling the types of crosslinks rather than by modifying the polymer itself. This strategy to decouple material mechanics from structure may inform the design of soft materials for use in complex mechanical environments. PMID:26322715

  3. Bio-Inspired Composite Interfaces: Controlling Hydrogel Mechanics via Polymer-Nanoparticle Coordination Bond Dynamics

    NASA Astrophysics Data System (ADS)

    Holten-Andersen, Niels

    2015-03-01

    In soft nanocomposite materials, the effective interaction between polymer molecules and inorganic nanoparticle surfaces plays a critical role in bulk mechanical properties. However, controlling these interfacial interactions remains a challenge. Inspired by the adhesive chemistry in mussel threads, we present a novel approach to control composite mechanics via polymer-particle interfacial dynamics; by incorporating iron oxide nanoparticles (Fe3O4 NPs) into a catechol-modified polymer network the resulting hydrogels are crosslinked via reversible coordination bonds at Fe3O4 NP surfaces thereby providing a dynamic gel network with robust self-healing properties. By studying the thermally activated composite network relaxation processes we have found that the polymer-NP binding energy can be controlled by engineering both the organic and inorganic side of the interface.

  4. Control of hierarchical polymer mechanics with bioinspired metal-coordination dynamics.

    PubMed

    Grindy, Scott C; Learsch, Robert; Mozhdehi, Davoud; Cheng, Jing; Barrett, Devin G; Guan, Zhibin; Messersmith, Phillip B; Holten-Andersen, Niels

    2015-12-01

    In conventional polymer materials, mechanical performance is traditionally engineered via material structure, using motifs such as polymer molecular weight, polymer branching, or block copolymer design. Here, by means of a model system of 4-arm poly(ethylene glycol) hydrogels crosslinked with multiple, kinetically distinct dynamic metal-ligand coordinate complexes, we show that polymer materials with decoupled spatial structure and mechanical performance can be designed. By tuning the relative concentration of two types of metal-ligand crosslinks, we demonstrate control over the material's mechanical hierarchy of energy-dissipating modes under dynamic mechanical loading, and therefore the ability to engineer a priori the viscoelastic properties of these materials by controlling the types of crosslinks rather than by modifying the polymer itself. This strategy to decouple material mechanics from structure is general and may inform the design of soft materials for use in complex mechanical environments. Three examples that demonstrate this are provided.

  5. Control of hierarchical polymer mechanics with bioinspired metal-coordination dynamics

    NASA Astrophysics Data System (ADS)

    Grindy, Scott C.; Learsch, Robert; Mozhdehi, Davoud; Cheng, Jing; Barrett, Devin G.; Guan, Zhibin; Messersmith, Phillip B.; Holten-Andersen, Niels

    2015-12-01

    In conventional polymer materials, mechanical performance is traditionally engineered via material structure, using motifs such as polymer molecular weight, polymer branching, or block copolymer design. Here, by means of a model system of 4-arm poly(ethylene glycol) hydrogels crosslinked with multiple, kinetically distinct dynamic metal-ligand coordinate complexes, we show that polymer materials with decoupled spatial structure and mechanical performance can be designed. By tuning the relative concentration of two types of metal-ligand crosslinks, we demonstrate control over the material’s mechanical hierarchy of energy-dissipating modes under dynamic mechanical loading, and therefore the ability to engineer a priori the viscoelastic properties of these materials by controlling the types of crosslinks rather than by modifying the polymer itself. This strategy to decouple material mechanics from structure is general and may inform the design of soft materials for use in complex mechanical environments. Three examples that demonstrate this are provided.

  6. High dynamic range charge measurements

    SciTech Connect

    De Geronimo, Gianluigi

    2012-09-04

    A charge amplifier for use in radiation sensing includes an amplifier, at least one switch, and at least one capacitor. The switch selectively couples the input of the switch to one of at least two voltages. The capacitor is electrically coupled in series between the input of the amplifier and the input of the switch. The capacitor is electrically coupled to the input of the amplifier without a switch coupled therebetween. A method of measuring charge in radiation sensing includes selectively diverting charge from an input of an amplifier to an input of at least one capacitor by selectively coupling an output of the at least one capacitor to one of at least two voltages. The input of the at least one capacitor is operatively coupled to the input of the amplifier without a switch coupled therebetween. The method also includes calculating a total charge based on a sum of the amplified charge and the diverted charge.

  7. Intermanual transfer characteristics of dynamic learning: direction, coordinate frame, and consolidation of interlimb generalization.

    PubMed

    Stockinger, Christian; Thürer, Benjamin; Focke, Anne; Stein, Thorsten

    2015-12-01

    Intermanual transfer, i.e., generalization of motor learning across hands, is a well-accepted phenomenon of motor learning. Yet, there are open questions regarding the characteristics of this transfer, particularly the intermanual transfer of dynamic learning. In this study, we investigated intermanual transfer in a force field adaptation task concerning the direction and the coordinate frame of transfer as well as the influence of a 24-h consolidation period on the transfer. We tested 48 healthy human subjects for transfer from dominant to nondominant hand, and vice versa. We considered two features of transfer. First, we examined transfer to the untrained hand using force channel trials that suppress error feedback and learning mechanisms to assess intermanual transfer in the form of a practice-dependent bias. Second, we considered transfer by exposing the subjects to the force field with the untrained hand to check for faster learning of the dynamics (interlimb savings). Half of the subjects were tested for transfer immediately after adaptation, whereas the other half were tested after a 24-h consolidation period. Our results showed intermanual transfer both from dominant to nondominant hand and vice versa in extrinsic coordinates. After the consolidation period, transfer effects were weakened. Moreover, the transfer effects were negligible compared with the subjects' ability to rapidly adapt to the force field condition. We conclude that intermanual transfer is a bidirectional phenomenon that vanishes with time. However, the ability to transfer motor learning seems to play a minor role compared with the rapid adaptation processes.

  8. GneimoSim: A Modular Internal Coordinates Molecular Dynamics Simulation Package

    PubMed Central

    Larsen, Adrien B.; Wagner, Jeffrey R.; Kandel, Saugat; Salomon-Ferrer, Romelia; Vaidehi, Nagarajan; Jain, Abhinandan

    2014-01-01

    The Generalized Newton Euler Inverse Mass Operator (GNEIMO) method is an advanced method for internal coordinates molecular dynamics (ICMD). GNEIMO includes several theoretical and algorithmic advancements that address longstanding challenges with ICMD simulations. In this paper we describe the GneimoSim ICMD software package that implements the GNEIMO method. We believe that GneimoSim is the first software package to include advanced features such as the equipartition principle derived for internal coordinates, and a method for including the Fixman potential to eliminate systematic statistical biases introduced by the use of hard constraints. Moreover, by design, GneimoSim is extensible and can be easily interfaced with third party force field packages for ICMD simulations. Currently, GneimoSim includes interfaces to LAMMPS, OpenMM, Rosetta force field calculation packages. The availability of a comprehensive Python interface to the underlying C++ classes and their methods provides a powerful and versatile mechanism for users to develop simulation scripts to configure the simulation and control the simulation flow. GneimoSim has been used extensively for studying the dynamics of protein structures, refinement of protein homology models, and for simulating large scale protein conformational changes with enhanced sampling methods. GneimoSim is not limited to proteins and can also be used for the simulation of polymeric materials. PMID:25263538

  9. Automatic Reaction Pathway Search via Combined Molecular Dynamics and Coordinate Driving Method.

    PubMed

    Yang, Manyi; Zou, Jingxiang; Wang, Guoqiang; Li, Shuhua

    2017-02-16

    We proposed and implemented a combined molecular dynamics and coordinate driving (MD/CD) method for automatically searching multistep reaction pathways of chemical reactions. In this approach, the molecular dynamic (MD) method at the molecular mechanics (MM) or semiempirical quantum mechanical (QM) level is employed to explore the conformational space of the minimum structures, and the modified coordinate driving (CD) method is used to build reaction pathways for representative conformers. The MD/CD method is first applied to two model reactions (the Claisen rearrangement and the intermolecular aldol reaction). By comparing the obtained results with those of the existing methods, we found that the MD/CD method has a comparable performance in searching low-energy reaction pathways. Then, the MD/CD method is further applied to investigate two reactions: the electrocyclic reaction of benzocyclobutene-7-carboxaldehyde and the intramolecular Diels-Alder reaction of ketothioester with 11 effectively rotatable single bonds. For the first reaction, our results can correctly account for its torquoselectivity. For the second one, our method predicts eight reaction channels, leading to eight different stereo- and regioselective products. The MD/CD method is expected to become an efficient and cost-effective theoretical tool for automatically searching low-energy reaction pathways for relatively complex chemical reactions.

  10. Overcoming potential energy distortions in constrained internal coordinate molecular dynamics simulations

    SciTech Connect

    Kandel, Saugat; Salomon-Ferrer, Romelia; Larsen, Adrien B.; Vaidehi, Nagarajan; Jain, Abhinandan

    2016-01-28

    The Internal Coordinate Molecular Dynamics (ICMD) method is an attractive molecular dynamics (MD) method for studying the dynamics of bonded systems such as proteins and polymers. It offers a simple venue for coarsening the dynamics model of a system at multiple hierarchical levels. For example, large scale protein dynamics can be studied using torsional dynamics, where large domains or helical structures can be treated as rigid bodies and the loops connecting them as flexible torsions. ICMD with such a dynamic model of the protein, combined with enhanced conformational sampling method such as temperature replica exchange, allows the sampling of large scale domain motion involving high energy barrier transitions. Once these large scale conformational transitions are sampled, all-torsion, or even all-atom, MD simulations can be carried out for the low energy conformations sampled via coarse grained ICMD to calculate the energetics of distinct conformations. Such hierarchical MD simulations can be carried out with standard all-atom forcefields without the need for compromising on the accuracy of the forces. Using constraints to treat bond lengths and bond angles as rigid can, however, distort the potential energy landscape of the system and reduce the number of dihedral transitions as well as conformational sampling. We present here a two-part solution to overcome such distortions of the potential energy landscape with ICMD models. To alleviate the intrinsic distortion that stems from the reduced phase space in torsional MD, we use the Fixman compensating potential. To additionally alleviate the extrinsic distortion that arises from the coupling between the dihedral angles and bond angles within a force field, we propose a hybrid ICMD method that allows the selective relaxing of bond angles. This hybrid ICMD method bridges the gap between all-atom MD and torsional MD. We demonstrate with examples that these methods together offer a solution to eliminate the potential

  11. Overcoming potential energy distortions in constrained internal coordinate molecular dynamics simulations

    PubMed Central

    Kandel, Saugat; Salomon-Ferrer, Romelia; Larsen, Adrien B.; Jain, Abhinandan; Vaidehi, Nagarajan

    2016-01-01

    The Internal Coordinate Molecular Dynamics (ICMD) method is an attractive molecular dynamics (MD) method for studying the dynamics of bonded systems such as proteins and polymers. It offers a simple venue for coarsening the dynamics model of a system at multiple hierarchical levels. For example, large scale protein dynamics can be studied using torsional dynamics, where large domains or helical structures can be treated as rigid bodies and the loops connecting them as flexible torsions. ICMD with such a dynamic model of the protein, combined with enhanced conformational sampling method such as temperature replica exchange, allows the sampling of large scale domain motion involving high energy barrier transitions. Once these large scale conformational transitions are sampled, all-torsion, or even all-atom, MD simulations can be carried out for the low energy conformations sampled via coarse grained ICMD to calculate the energetics of distinct conformations. Such hierarchical MD simulations can be carried out with standard all-atom forcefields without the need for compromising on the accuracy of the forces. Using constraints to treat bond lengths and bond angles as rigid can, however, distort the potential energy landscape of the system and reduce the number of dihedral transitions as well as conformational sampling. We present here a two-part solution to overcome such distortions of the potential energy landscape with ICMD models. To alleviate the intrinsic distortion that stems from the reduced phase space in torsional MD, we use the Fixman compensating potential. To additionally alleviate the extrinsic distortion that arises from the coupling between the dihedral angles and bond angles within a force field, we propose a hybrid ICMD method that allows the selective relaxing of bond angles. This hybrid ICMD method bridges the gap between all-atom MD and torsional MD. We demonstrate with examples that these methods together offer a solution to eliminate the potential

  12. Overcoming potential energy distortions in constrained internal coordinate molecular dynamics simulations

    NASA Astrophysics Data System (ADS)

    Kandel, Saugat; Salomon-Ferrer, Romelia; Larsen, Adrien B.; Jain, Abhinandan; Vaidehi, Nagarajan

    2016-01-01

    The Internal Coordinate Molecular Dynamics (ICMD) method is an attractive molecular dynamics (MD) method for studying the dynamics of bonded systems such as proteins and polymers. It offers a simple venue for coarsening the dynamics model of a system at multiple hierarchical levels. For example, large scale protein dynamics can be studied using torsional dynamics, where large domains or helical structures can be treated as rigid bodies and the loops connecting them as flexible torsions. ICMD with such a dynamic model of the protein, combined with enhanced conformational sampling method such as temperature replica exchange, allows the sampling of large scale domain motion involving high energy barrier transitions. Once these large scale conformational transitions are sampled, all-torsion, or even all-atom, MD simulations can be carried out for the low energy conformations sampled via coarse grained ICMD to calculate the energetics of distinct conformations. Such hierarchical MD simulations can be carried out with standard all-atom forcefields without the need for compromising on the accuracy of the forces. Using constraints to treat bond lengths and bond angles as rigid can, however, distort the potential energy landscape of the system and reduce the number of dihedral transitions as well as conformational sampling. We present here a two-part solution to overcome such distortions of the potential energy landscape with ICMD models. To alleviate the intrinsic distortion that stems from the reduced phase space in torsional MD, we use the Fixman compensating potential. To additionally alleviate the extrinsic distortion that arises from the coupling between the dihedral angles and bond angles within a force field, we propose a hybrid ICMD method that allows the selective relaxing of bond angles. This hybrid ICMD method bridges the gap between all-atom MD and torsional MD. We demonstrate with examples that these methods together offer a solution to eliminate the potential

  13. Overcoming potential energy distortions in constrained internal coordinate molecular dynamics simulations.

    PubMed

    Kandel, Saugat; Salomon-Ferrer, Romelia; Larsen, Adrien B; Jain, Abhinandan; Vaidehi, Nagarajan

    2016-01-28

    The Internal Coordinate Molecular Dynamics (ICMD) method is an attractive molecular dynamics (MD) method for studying the dynamics of bonded systems such as proteins and polymers. It offers a simple venue for coarsening the dynamics model of a system at multiple hierarchical levels. For example, large scale protein dynamics can be studied using torsional dynamics, where large domains or helical structures can be treated as rigid bodies and the loops connecting them as flexible torsions. ICMD with such a dynamic model of the protein, combined with enhanced conformational sampling method such as temperature replica exchange, allows the sampling of large scale domain motion involving high energy barrier transitions. Once these large scale conformational transitions are sampled, all-torsion, or even all-atom, MD simulations can be carried out for the low energy conformations sampled via coarse grained ICMD to calculate the energetics of distinct conformations. Such hierarchical MD simulations can be carried out with standard all-atom forcefields without the need for compromising on the accuracy of the forces. Using constraints to treat bond lengths and bond angles as rigid can, however, distort the potential energy landscape of the system and reduce the number of dihedral transitions as well as conformational sampling. We present here a two-part solution to overcome such distortions of the potential energy landscape with ICMD models. To alleviate the intrinsic distortion that stems from the reduced phase space in torsional MD, we use the Fixman compensating potential. To additionally alleviate the extrinsic distortion that arises from the coupling between the dihedral angles and bond angles within a force field, we propose a hybrid ICMD method that allows the selective relaxing of bond angles. This hybrid ICMD method bridges the gap between all-atom MD and torsional MD. We demonstrate with examples that these methods together offer a solution to eliminate the potential

  14. Determination of validation threshold for coordinate measuring methods using a metrological compatibility model

    NASA Astrophysics Data System (ADS)

    Gromczak, Kamila; Gąska, Adam; Kowalski, Marek; Ostrowska, Ksenia; Sładek, Jerzy; Gruza, Maciej; Gąska, Piotr

    2017-01-01

    The following paper presents a practical approach to the validation process of coordinate measuring methods at an accredited laboratory, using a statistical model of metrological compatibility. The statistical analysis of measurement results obtained using a highly accurate system was intended to determine the permissible validation threshold values. The threshold value constitutes the primary criterion for the acceptance or rejection of the validated method, and depends on both the differences between measurement results with corresponding uncertainties and the individual correlation coefficient. The article specifies and explains the types of measuring methods that were subject to validation and defines the criterion value governing their acceptance or rejection in the validation process.

  15. Standard conforming involute gear metrology using an articulated arm coordinate measuring system

    NASA Astrophysics Data System (ADS)

    Härtig, Frank; Lin, Hu; Kniel, Karin; Shi, Zhaoyao

    2012-10-01

    Standard conforming involute gear measurements were taken by a manually operating articulated arm system and the respective task-specific measurement uncertainties were estimated. User-friendly templates were developed to provide almost unambiguous and repeatable measurement results. They allow the metrologist to easily detect and gather the single measurement points according to existing guidelines and standards commonly used in gear metrology. The research activities were carried out at the Physikalisch-Technische Bundesanstalt (PTB), Germany in the Department of Coordinate Metrology. Measurements were taken on a robust and highly accurate large gear measurement standard of PTB, in the following called the gear standard. This gear standard materializes a left-hand and a right-hand gear as well as a spur gear. The 1 m outside diameter of the gear standard is similar to the gears used in wind power plants. A commercial articulated arm coordinate measuring system was used for the measurements. A high temperature stability of ±0.2 °C was provided to minimize thermal influences. The results of profile and helix measurements will be presented. This worldwide first investigation, on the basis of a calibrated involute gear standard, gives users of the articulating arm system quantitative information on a task-specific performance of a representative gear measurement.

  16. Mars 2001 Lander Mission: Measurement Synergy Through Coordinated Operations Planning And Implementation

    NASA Technical Reports Server (NTRS)

    Arvidson, R.; Bell, J. F., III; Kaplan, D.; Marshall, J.; Mishkin, A.; Saunders, S.; Smith, P.; Squyres, S.

    1999-01-01

    , together with quantitative information on material mineralogy, chemistry, and physical properties (rock textures; soil grain size and shape distributions; degree and nature of soil induration; soil magnetic properties). The calibration targets provide radiometric and mineralogical control surfaces. The magnets allow observations of magnetic phases. Patch plates are imaged to determine adhesive and abrasive properties of soils. Coordinated mission planning is crucial for optimizing the measurement synergy among the packages included on the lander. This planning has already begun through generation of multi-sol detailed operations activities. One focus has been to develop a scenario to use the arm to dig a soil trench to a depth of tens of centimeters. The activity will be monitored through use of Pancam and RAC to ensure nominal operations and to acquire data to determine subsurface physical properties (e.g., angle of repose of trench walls). Pancam and Mini-TES observations would also provide constraints on mineralogy and texture for the walls and bottom of the trench during excavation. If desired, soils excavated at depth could be deposited on the surface and Mossbauer and APXS measurements could be acquired for these materials. Soil samples from various depths would be delivered to MECA for characterization of aqueous geochemistry and physical properties of soil grains, particularly size, shape, and hardness. These physical properties would be determined by optical and atomic force microscopy. When completed, detailed information of soil properties as a function of depth would be obtained. These various data sets would constrain our understanding of whether or not there are systematic variations in soil characteristics as a function of depth. These variations might be related, for example, to evaporative moisture losses and formation of salt deposits, thereby indicating water transport processes occurred fairly recently. Many other value-added measurement scenarios are

  17. Local and global measures of shape dynamics

    NASA Astrophysics Data System (ADS)

    Driscoll, Meghan K.; Fourkas, John T.; Losert, Wolfgang

    2011-10-01

    The shape and motion of cells can yield significant insights into the internal operation of a cell. We present a simple, yet versatile, framework that provides multiple metrics of cell shape and cell shape dynamics. Analysis of migrating Dictyostelium discoideum cells shows that global and local metrics highlight distinct cellular processes. For example, a global measure of shape shows rhythmic oscillations suggestive of contractions, whereas a local measure of shape shows wave-like dynamics indicative of protrusions. From a local measure of dynamic shape, or boundary motion, we extract the times and locations of protrusions and retractions. We find that protrusions zigzag, while retractions remain roughly stationary along the boundary. We do not observe any temporal relationship between protrusions and retractions. Our analysis framework also provides metrics of the boundary as whole. For example, as the cell speed increases, we find that the cell shape becomes more elongated. We also observe that while extensions and retractions have similar areas, their shapes differ.

  18. Relative position finite-time coordinated tracking control of spacecraft formation without velocity measurements.

    PubMed

    Hu, Qinglei; Zhang, Jian

    2015-01-01

    This paper investigates finite-time relative position coordinated tracking problem by output feedback for spacecraft formation flying without velocity measurement. By employing homogeneous system theory, a finite-time relative position coordinated tracking controller by state feedback is firstly developed, where the desired time-varying trajectory given in advance can be tracked by the formation. Then, to address the problem of lack of velocity measurements, a finite-time output feedback controller is proposed by involving a novel filter to recover unknown velocity information in a finite time. Rigorous proof shows that the proposed control law ensures global stability and guarantees the position of spacecraft formation to track a time-varying reference in finite time. Finally, simulation results are presented to illustrate the performance of the proposed controller.

  19. The impact of Wii Fit intervention on dynamic balance control in children with probable Developmental Coordination Disorder and balance problems.

    PubMed

    Jelsma, Dorothee; Geuze, Reint H; Mombarg, Remo; Smits-Engelsman, Bouwien C M

    2014-02-01

    The aim of this study was to examine differences in the performance of children with probable Developmental Coordination Disorder (p-DCD) and balance problems (BP) and typical developing children (TD) on a Wii Fit task and to measure the effect on balance skills after a Wii Fit intervention. Twenty-eight children with BP and 20 TD-children participated in the study. Motor performance was assessed with the Movement Assessment Battery for Children (MABC2), three subtests of the Bruininks Oseretsky Test (BOT2): Bilateral Coordination, Balance and Running Speed & Agility, and a Wii Fit ski slalom test. The TD children and half of the children in the BP group were tested before and after a 6weeks non-intervention period. All children with BP received 6weeks of Wii Fit intervention (with games other than the ski game) and were tested before and afterwards. Children with BP were less proficient than TD children in playing the Wii Fit ski slalom game. Training with the Wii Fit improved their motor performance. The improvement was significantly larger after intervention than after a period of non-intervention. Therefore the change cannot solely be attributed to spontaneous development or test-retest effect. Nearly all children enjoyed participation during the 6weeks of intervention. Our study shows that Wii Fit intervention is effective and is potentially a method to support treatment of (dynamic) balance control problems in children.

  20. Computing the Free Energy along a Reaction Coordinate Using Rigid Body Dynamics.

    PubMed

    Tao, Peng; Sodt, Alexander J; Shao, Yihan; König, Gerhard; Brooks, Bernard R

    2014-10-14

    The calculations of potential of mean force along complex chemical reactions or rare events pathways are of great interest because of their importance for many areas in chemistry, molecular biology, and material science. The major difficulty for free energy calculations comes from the great computational cost for adequate sampling of the system in high-energy regions, especially close to the reaction transition state. Here, we present a method, called FEG-RBD, in which the free energy gradients were obtained from rigid body dynamics simulations. Then the free energy gradients were integrated along a reference reaction pathway to calculate free energy profiles. In a given system, the reaction coordinates defining a subset of atoms (e.g., a solute, or the quantum mechanics (QM) region of a quantum mechanics/molecular mechanics simulation) are selected to form a rigid body during the simulation. The first-order derivatives (gradients) of the free energy with respect to the reaction coordinates are obtained through the integration of constraint forces within the rigid body. Each structure along the reference reaction path is separately subjected to such a rigid body simulation. The individual free energy gradients are integrated along the reference pathway to obtain the free energy profile. Test cases provided demonstrate both the strengths and weaknesses of the FEG-RBD method. The most significant benefit of this method comes from the fast convergence rate of the free energy gradient using rigid-body constraints instead of restraints. A correction to the free energy due to approximate relaxation of the rigid-body constraint is estimated and discussed. A comparison with umbrella sampling using a simple test case revealed the improved sampling efficiency of FEG-RBD by a factor of 4 on average. The enhanced efficiency makes this method effective for calculating the free energy of complex chemical reactions when the reaction coordinate can be unambiguously defined by a

  1. Comparison of calculated with measured dynamic aperture

    SciTech Connect

    Zimmermann, F.

    1994-06-01

    The measured dynamic aperture of the HERA proton ring and the value expected from simulation studies agree within a factor of 2. A better agreement is achieved if a realistic tune modulation is included in the simulation. The approximate threshold of tune-modulation induced diffusion can be calculated analytically. Its value is in remarkable agreement with the dynamic aperture measured. The calculation is based on parameters of resonances through order 11 which are computed using differential-algebra methods and normal-form algorithms. Modulational diffusion in conjunction with drifting machine parameters appears to be the most important transverse diffusion process.

  2. Decipher the dynamic coordination between enzymatic activity and structural modulation at focal adhesions in living cells

    NASA Astrophysics Data System (ADS)

    Lu, Shaoying; Seong, Jihye; Wang, Yi; Chang, Shiou-Chi; Eichorst, John Paul; Ouyang, Mingxing; Li, Julie Y.-S.; Chien, Shu; Wang, Yingxiao

    2014-07-01

    Focal adhesions (FAs) are dynamic subcellular structures crucial for cell adhesion, migration and differentiation. It remains an enigma how enzymatic activities in these local complexes regulate their structural remodeling in live cells. Utilizing biosensors based on fluorescence resonance energy transfer (FRET), we developed a correlative FRET imaging microscopy (CFIM) approach to quantitatively analyze the subcellular coordination between the enzymatic Src activation and the structural FA disassembly. CFIM reveals that the Src kinase activity only within the microdomain of lipid rafts at the plasma membrane is coupled with FA dynamics. FA disassembly at cell periphery was linearly dependent on this raft-localized Src activity, although cells displayed heterogeneous levels of response to stimulation. Within lipid rafts, the time delay between Src activation and FA disassembly was 1.2 min in cells seeded on low fibronectin concentration ([FN]) and 4.3 min in cells on high [FN]. CFIM further showed that the level of Src-FA coupling, as well as the time delay, was regulated by cell-matrix interactions, as a tight enzyme-structure coupling occurred in FA populations mediated by integrin αvβ3, but not in those by integrin α5β1. Therefore, different FA subpopulations have distinctive regulation mechanisms between their local kinase activity and structural FA dynamics.

  3. Dynamic measurement technology in object separate experiment

    NASA Astrophysics Data System (ADS)

    Song, Jin Cheng; Liang, Yajun; Guo, Lei; Sun, Zengyu

    2013-01-01

    In this paper, a novel experimental method is proposed in order to verify the availability and reliability in separate system. To measure the position-change caused by the fault-mode machine-separate of the electric isolator plug and to know the real switch process of the important component, the ground separate experiment is required to simulate the real object separate process and to obtain the relative position of isolate component under different separate parameter. In the experiment, a position measurement system based on high speed photograph principle is introduced which has hardware, software and gauging method of photograph measure system. A in-situ measurement system is set up by two high speed camera in order to synchronized image collection of separate process. After extracting, matching, coordinate and position calculating to the image, a relative position of the isolator component at the time of separate process can be deduced. The relative separate speed at this time can be calculated by the position parameter. The measurement system can be tested by the three-axis standard revolving stage. The results of the measurement experiment show that camera response frequency is 1000Hz, the relative error of position measurement is less than 5%, the relative error of speed measurement is less than 5% which can meet demands of experiment.

  4. Modern CCD Observations of Selected Minor Planets for the Connection of Dynamic and Kinematic Coordinate Systems

    NASA Astrophysics Data System (ADS)

    Pomazan, A.; Maigurova, N.

    2016-12-01

    One of the methods of determining the orientation parameters of the dynamic and kinematic coordinate systems is to use of long-term series of ground-based observations of selected asteroids. For achievement of the best accuracy of the link parameters the high precision and uniformly covering the asteroids orbit observations are necessary. The analysis of the available observations of selected asteroids was made with usage MPC database. The value of the true anomaly at the moment of observation was selected as parameter of orbit covering. It is shown that there are orbital segments without precise observations. This was taken into account when forming the observational list for the telescope KT-50 (Mobitel complex). 1596 positions of 50 asteroid have been obtained during 2014- 2016. The comparison of the calculated positions with ephemeris obtained by on-line service HORIZONS was made. The RMS errors of the differences (O-C) were about 0.1 arcsec for both coordinates. The comparison of the obtained results with observations of the some ground based observatories and Hipparcos satellite shows high accuracy and uniformity of Nikolaev asteroid observations.

  5. Coordinating two-period ordering and advertising policies in a dynamic market with stochastic demand

    NASA Astrophysics Data System (ADS)

    Wang, Junping; Wang, Shengdong; Min, Jie

    2015-03-01

    In this paper, we study the optimal two-stage advertising and ordering policies and the channel coordination issues in a supply chain composed of one manufacturer and one retailer. The manufacturer sells a short-life-cycle product through the retailer facing stochastic demand in dynamic markets characterised by price declines and product obsolescence. Following a two-period newsvendor framework, we develop two members' optimal ordering and advertising models under both the centralised and decentralised settings, and present the closed-form solutions to the developed models as well. Moreover, we design a two-period revenue-sharing contract, and develop sufficient conditions such that the channel coordination can be achieved and a win-win outcome can be guaranteed. Our analysis suggests that the centralised decision creates an incentive for the retailer to increase the advertising investments in two periods and put the purchase forward, but the decentralised decision mechanism forces the retailer to decrease the advertising investments in two periods and postpone/reduce its purchase in the first period. This phenomenon becomes more evident when demand variability is high.

  6. Use of global positioning system measurements to determine geocentric coordinates and variations in Earth orientation

    NASA Technical Reports Server (NTRS)

    Malla, R. P.; Wu, S.-C.; Lichten, S. M.

    1993-01-01

    Geocentric tracking station coordinates and short-period Earth-orientation variations can be measured with Global Positioning System (GPS) measurements. Unless calibrated, geocentric coordinate errors and changes in Earth orientation can lead to significant deep-space tracking errors. Ground-based GPS estimates of daily and subdaily changes in Earth orientation presently show centimeter-level precision. Comparison between GPS-estimated Earth-rotation variations, which are the differences between Universal Time 1 and Universal Coordinated Time (UT1-UTC), and those calculated from ocean tide models suggests that observed subdaily variations in Earth rotation are dominated by oceanic tidal effects. Preliminary GPS estimates for the geocenter location (from a 3-week experiment) agree with independent satellite laser-ranging estimates to better than 10 cm. Covariance analysis predicts that temporal resolution of GPS estimates for Earth orientation and geocenter improves significantly when data collected from low Earth-orbiting satellites as well as from ground sites are combined. The low Earth GPS tracking data enhance the accuracy and resolution for measuring high-frequency global geodynamical signals over time scales of less than 1 day.

  7. Under lock and key: Spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processes

    PubMed Central

    Burianek, Lauren E.; Soderling, Scott H.

    2013-01-01

    WASP family proteins are nucleation promoting factors that bind to and activate the Arp2/3 complex in order to stimulate nucleation of branched actin filaments. The WASP family consists of WASP, N-WASP, WAVE1-3, WASH, and the novel family members WHAMM and JMY. Each of the family members contains a C-terminus responsible for their nucleation promoting activity and unique N-termini that allow for them to be regulated in a spatiotemporal manner. Upon activation they reorganize the cytoskeleton for different cellular functions depending on their subcellular localization and regulatory protein interactions. Emerging evidence indicates that WASH, WHAMM, and JMY have functions that require the coordination of both actin polymerization and microtubule dynamics. Here, we review the mechanisms of regulation for each family member and their associated in vivo functions including cell migration, vesicle trafficking, and neuronal development. PMID:23291261

  8. Event heap: a coordination infrastructure for dynamic heterogeneous application interactions in ubiquitous computing environments

    DOEpatents

    Johanson, Bradley E.; Fox, Armando; Winograd, Terry A.; Hanrahan, Patrick M.

    2010-04-20

    An efficient and adaptive middleware infrastructure called the Event Heap system dynamically coordinates application interactions and communications in a ubiquitous computing environment, e.g., an interactive workspace, having heterogeneous software applications running on various machines and devices across different platforms. Applications exchange events via the Event Heap. Each event is characterized by a set of unordered, named fields. Events are routed by matching certain attributes in the fields. The source and target versions of each field are automatically set when an event is posted or used as a template. The Event Heap system implements a unique combination of features, both intrinsic to tuplespaces and specific to the Event Heap, including content based addressing, support for routing patterns, standard routing fields, limited data persistence, query persistence/registration, transparent communication, self-description, flexible typing, logical/physical centralization, portable client API, at most once per source first-in-first-out ordering, and modular restartability.

  9. Dynamics of the 1054 UT March 22, 1979, substorm event - CDAW 6. [Coordinated Data Analysis Workshop

    NASA Technical Reports Server (NTRS)

    Mcpherron, R. L.; Manka, R. H.

    1985-01-01

    The Coordinated Data Analysis Workshop (CDAW 6) has the primary objective to trace the flow of energy from the solar wind through the magnetosphere to its ultimate dissipation in the ionosphere. An essential role in this energy transfer is played by magnetospheric substorms, however, details are not yet completely understood. The International Magnetospheric Study (IMS) has provided an ideal data base for the study conducted by CDAW 6. The present investigation is concerned with the 1054 UT March 22, 1979, substorm event, which had been selected for detailed examination in connection with the studies performed by the CDAW 6. The observations of this substorm are discussed, taking into account solar wind conditions, ground magnetic activity on March 22, 1979, observations at synchronous orbit, observations in the near geomagnetic tail, and the onset of the 1054 UT expansion phase. Substorm development and magnetospheric dynamics are discussed on the basis of a synthesis of the observations.

  10. Measuring Dynamic Transfer Functions of Cavitating Pumps

    NASA Technical Reports Server (NTRS)

    Baun, Daniel

    2007-01-01

    A water-flow test facility has been built to enable measurement of dynamic transfer functions (DTFs) of cavitating pumps and of inducers in such pumps. Originally, the facility was intended for use in an investigation of the effects of cavitation in a rocket-engine low-pressure oxygen turbopump. The facility can also be used to measure DTFs of cavitating pumps in general

  11. Solar radiation measurements from coordinated radiosonde flights during the 20th March 2015 solar eclipse

    NASA Astrophysics Data System (ADS)

    Harrison, R. Giles; Marlton, Graeme; Williams, Paul; Nicoll, Keri

    2016-04-01

    Solar radiation sensors can be carried on standard weather balloon packages and provide additional information about the atmosphere's vertical structure beyond the traditional thermodynamic measurements [1]. An interesting set of circumstances for such sensors occurs during a solar eclipse, which provides a rapidly changing solar radiation environment within the duration of a typical free balloon flight. Coordinating several launches of solar radiation measuring radiosondes brings a good likelihood of at least one being above any cloud during the maximum eclipse, allowing solar eclipse radiation measurements for comparison with theory. For the 20th March 2015 solar eclipse, a coordinated campaign of balloon-carried solar radiation measurements was undertaken from Reading (51.44N, 0.94W), Lerwick (60.15N, 1.13W) and Reykjavik (64.13N, 21.90W), straddling the path of the eclipse. All three balloons reached sufficient altitude at the eclipse time for eclipse-induced variations in solar radiation and solar limb darkening to be measured above cloud. Because the sensor platforms were free to swing, techniques have been evaluated to correct the measurements for their changing orientation. These approaches, which are essentially independent, give values that agree with theoretical expectations for the eclipse-induced radiation changes. [1] K.A. Nicoll and R.G. Harrison, Balloon-borne disposable radiometer Rev Sci Instrum 83, 025111 (2012) doi: 10.1063/1.3685252

  12. Measuring Group Dynamics: An Exploratory Trial

    ERIC Educational Resources Information Center

    Phan, Loan T.; Rivera, Edil Torres; Volker, Martin A.; Garrett, Michael T.

    2004-01-01

    This article reports on the development of a scale used to assess and measure group dynamics during group supervision counselling courses (practicum and internship). A 20-item Likert-type scale was administered to 200 counsellors-in-training master's students. Reliability and validity data are described. An exploratory factor analysis yielded…

  13. Conditional measurements as probes of quantum dynamics

    SciTech Connect

    Siddiqui, Shabnam; Erenso, Daniel; Vyas, Reeta; Singh, Surendra

    2003-06-01

    We discuss conditional measurements as probes of quantum dynamics and show that they provide different ways to characterize quantum fluctuations. We illustrate this by considering the light from a subthreshold degenerate parametric oscillator. Analytic results and curves are presented to illustrate the behavior.

  14. Semirigid aromatic sulfone-carboxylate molecule for dynamic coordination networks: multiple substitutions of the ancillary ligands.

    PubMed

    Zhou, Xiao-Ping; Xu, Zhengtao; Zeller, Matthias; Hunter, Allen D; Chui, Stephen Sin-Yin; Che, Chi-Ming

    2011-08-01

    We report dynamic, multiple single-crystal to single-crystal transformations of a coordination network system based on a semirigid molecule, TCPSB = 1,3,5-tri(4'-carboxyphenylsulphonyl)benzene, which nicely balances shape persistence and flexibility to bring about the framework dynamics in the solid state. The networks here generally consist of (1) the persistent core component (denoted as CoTCPSB) of linear Co(II) aqua clusters (Co-O-Co-O-Co) integrated into 2D grids by 4,4'-bipyridine and TCPSB and (2) ancillary ligands (AL) on the two terminal Co(II) ions-these include DMF (N,N'-dimethylformamide), DMA (N,N'-dimethylacetamide), CH(3)CN, and water. Most notably, the ancillary ligand sites are highly variable and undergo multiple substitution sequences while maintaining the solid reactants/products as single-crystals amenable to X-ray structure determinations. For example, when immersed in CH(3)CN, the AL of an as-made single crystal of CoTCPSB-DMF (i.e., DMF being the AL) is replaced to form CoTCPSB-CH(3)CN, which, in air, readily loses CH(3)CN to form CoTCPSB-H(2)O; the CoTCPSB-H(2)O single crystals, when placed in DMF, give back CoTCPSB-DMF in single-crystal form. Other selective, dynamic exchanges include the following: CoTCPSB-DMF reacts with CH(3)CN (to form CoTCPSB-CH(3)CN) but NOT with water, methanol, ethanol, DMA, or pyridine; CoTCPSB-H(2)O specifically pick outs DMF from a mixture of DMF, DMA, and DEF; an amorphous, dehydrated solid from CoTCPSB-H(2)O regains crystalline order simply by immersion in DMF (to form CoTCPSB-DMF). Further exploration with functional, semirigid ligands like TCPSB shall continue to uncover a wider array of advanced dynamic behaviors in solid state materials.

  15. Integrated calibration sphere and calibration step fixture for improved coordinate measurement machine calibration

    DOEpatents

    Clifford, Harry J [Los Alamos, NM

    2011-03-22

    A method and apparatus for mounting a calibration sphere to a calibration fixture for Coordinate Measurement Machine (CMM) calibration and qualification is described, decreasing the time required for such qualification, thus allowing the CMM to be used more productively. A number of embodiments are disclosed that allow for new and retrofit manufacture to perform as integrated calibration sphere and calibration fixture devices. This invention renders unnecessary the removal of a calibration sphere prior to CMM measurement of calibration features on calibration fixtures, thereby greatly reducing the time spent qualifying a CMM.

  16. Heuristic planning in feature-based inspection for coordinate measuring machines

    NASA Astrophysics Data System (ADS)

    Delvalle, Robert B.; Merat, Francis L.; Ruegsegger, Steve; Roumina, Kavous

    1993-03-01

    This system is a practical application of intelligent reasoning about the planning and sequencing of inspection tasks performed by a coordinate measuring machine (CMM). This research is part of an Air Force supported effort to develop a feature-based concurrent engineering system using an object-oriented development platform. Manipulation of design, manufacturing, and inspection features (in this system) is unique in that features are transformed into domain specific objects rather than degraded into elementary geometry. The object-oriented platform provides a means for transformation through built-in qualities such as inheritance, tree-search, and a cohesive part/sub-part organization. Inspection features represent not only geometry, but references to a world coordinate system, proper probe approach, and preferred evaluation method. Reasoning through inspection rules forms a single data object which can then be transformed into CMM executable code.

  17. Predictive-model-based dynamic coordination control strategy for power-split hybrid electric bus

    NASA Astrophysics Data System (ADS)

    Zeng, Xiaohua; Yang, Nannan; Wang, Junnian; Song, Dafeng; Zhang, Nong; Shang, Mingli; Liu, Jianxin

    2015-08-01

    Parameter-matching methods and optimal control strategies of the top-selling hybrid electric vehicle (HEV), namely, power-split HEV, are widely studied. In particular, extant research on control strategy focuses on the steady-state energy management strategy to obtain better fuel economy. However, given that multi-power sources are highly coupled in power-split HEVs and influence one another during mode shifting, conducting research on dynamic coordination control strategy (DCCS) to achieve riding comfort is also important. This paper proposes a predictive-model-based DCCS. First, the dynamic model of the objective power-split HEV is built and the mode shifting process is analyzed based on the developed model to determine the reason for the system shock generated. Engine torque estimation algorithm is then designed according to the principle of the nonlinear observer, and the prediction model of the degree of shock is established based on the theory of model predictive control. Finally, the DCCS with adaptation for a complex driving cycle is realized by combining the feedback control and the predictive model. The presented DCCS is validated on the co-simulation platform of AMESim and Simulink. Results show that the shock during mode shifting is well controlled, thereby improving riding comfort.

  18. Measurement uncertainty on the circular features in coordinate measurement system based on the error ellipse and Monte Carlo methods

    NASA Astrophysics Data System (ADS)

    Du, Zhengchun; Zhu, Mengrui; Wu, Zhaoyong; Yang, Jianguo

    2016-12-01

    The uncertainty determination of the geometrical feature measurement for coordinate measuring machines (CMMs) is an essential part in the reliable quality control process. However, the most commonly-used methods for uncertainty assessment are difficult and require not only a large number of repeated measurements but also rich operation experience. Based on the error ellipse theory and the Monte Carlo simulation method, an uncertainty evaluation method for CMM measurements is presented. For circular features, the uncertainty evaluation model was established and extended into the use of an application of two holes’ central distance measurement through Monte Carlo Simulation. The verification experiment of the new method was conducted and results were compared with the traditional ones and they fit reasonably well, which proved the validity of the proposed method.

  19. Handwriting measures as reflectors of executive functions among adults with Developmental Coordination Disorders (DCD)

    PubMed Central

    Rosenblum, Sara

    2013-01-01

    Planning ahead and organizational abilities in time and space are ingredients of high-level cognitive functions labeled as ‘Executive Functions’ (EF) required for daily activities such as writing or home management. EF deficits are considered a possible underlying brain mechanism involved in Developmental Coordination Disorders (DCD). The aim: of the study was to compare the handwriting process measures and the planning and organizational abilities in space and time of students with DCD with those of matched controls and to find whether handwriting measures can predict daily planning and organizational abilities among students with DCD. Method: 30 students diagnosed with DCD, between the ages of 24–41, and 30 age- and gender-matched controls participated in the study. They filled out the Handwriting Proficiency Screening Questionnaire (HPSQ) and the Adult Developmental Co-ordination Disorders Checklist (ADC). Furthermore, they copied a paragraph on a digitizer that is part of a computerized system Computerised Penmanship Evaluation Toll (ComPET). Results: Significant group differences were found for the HPSQ subscales scores as well as for the temporal and spatial measures of the paragraph copy task. Significant group differences were also found for the planning and organizational abilities in space and time as reflected through the ADC subscales. Significant medium correlations were found in both groups between the mean HPSQ time subscale and the ADC-B subscale mean score (r = 0.50/0.58, p < 0.05). Series of regression analyses indicated that two handwriting performance measures (mean HPSQ time subscale and mean stroke duration) predicted 19% of planning and organizational abilities as reflected through daily functions (ADC-B) [F(3, 54) = 38.37, β = 0.40, p < 0.0001]. Conclusion: The results support previous evidence about EF deficits as an underlying brain mechanism involved in motor coordination disorders, their significance as related to theoretical

  20. Plans for coordinated measurements around Mars with the Mars Express and MAVEN spacecraft

    NASA Astrophysics Data System (ADS)

    Witasse, O. G.; Cardesin-Moinelo, A.; Jakosky, B. M.; Grebowsky, J. M.; Lillis, R. J.; Opgenoorth, H. J.

    2012-12-01

    The NASA MAVEN spacecraft will launch in November, 2013, will arrive at Mars in September, 2014, and will begin its year-long primary science mission at the start of November, 2014. Its main goals are to characterize in detail the state of the Mars' upper atmosphere and to determine the role that loss of atmospheric gas to space played in changing the Martian climate through time. The ESA Mars Express mission is in orbit since December 2003. It includes a comprehensive payload suite for the study of the Mars' aeronomy. Hence, scientific investigations with both missions are very complementary. From the end of 2014 onwards, both spacecraft will be able to perform coordinated measurements. There is significant overlap in instrumentation between MAVEN and Mars Express (e.g., with measurements of electrons and ions), yet also significant differences (mass spectrometer and magnetometer on MAVEN, solar/stellar occultations and some energetic neutrals on Mars Express). This allows a combination of measurements that are more extensive, and therefore more valuable, than the complete data set from either mission. In addition, the orbits are complementary, and will provide a number of interesting geometrical configurations that will allows exploring the atmosphere with two points and thus separating time-varying from spatially varying phenomena. This paper will describe preliminary plans for coordinated measurements with the two platforms.

  1. On the Dynamic Measurements of Hydraulic Characteristics

    NASA Astrophysics Data System (ADS)

    Hasmatuchi, Vlad; Bosioc, Alin; Münch-Alligné, Cécile

    2016-11-01

    The present work introduces the implementation and validation of a faster method to measure experimentally the efficiency characteristics of hydraulic turbomachines at a model scale on a test rig. The case study is represented by a laboratory prototype of an in-line axial microturbine for water supply networks. The 2.65 kW one-stage variable speed turbine, composed by one upstream 5-blade runner followed by one counter-rotating downstream 7-blade runner, has been installed on the HES-SO Valais/Wallis universal test rig dedicated to assess performances of small hydraulic machinery following the IEC standard recommendations. In addition to the existing acquisition/control system of the test rig used to measure the 3D hill-chart of a turbine by classical static point-by-point method, a second digitizer has been added to acquire synchronized dynamic signals of the employed sensors. The optimal acceleration/deceleration ramps of the electrical drives have been previously identified in order to cope with the purpose of a reduced measurement time while avoiding errors and hysteresis on the acquired hydraulic characteristics. Finally, the comparison between the turbine efficiency hill-charts obtained by dynamic and static point-by-point methods shows a very good agreement in terms of precision and repeatability. Moreover, the applied dynamic method reduces significantly (by a factor of up to ten) the time necessary to measure the efficiency characteristics on model testing.

  2. Biophysical isopycnic-coordinate modelling of plankton dynamics in the Arabian Sea

    NASA Astrophysics Data System (ADS)

    Olascoaga, M. J.; Idrisi, N.; Romanou, A.

    A Nutrient-Phytoplankton-Zooplankton-Detritus (NPZD) ecosystem model is coupled to the Miami Isopycnic-Coordinate Ocean Model (MICOM) to study plankton dynamics in the Arabian Sea. Experiments oriented to testing the NPZD-MICOM coupled model sensitivity to variations in several parameters are performed. Particular attention is paid to the rates of detritus sinking and maximum phytoplankton growth rate. The coarse features of the blooms are captured by all the experiments considered, and agree with earlier models for the biological activity of the region. Intensity, duration, and peaks of the blooms are found to be quite sensitive to the parameter choices. The existence of an offshore deep chlorophyll maximum in the model is found to be closely related to the increase of the detritus sinking rate. The use of temperature-dependent maximum growth rate of phytoplankton and the increase of detritus sinking rate are shown to improve model results compared with in situ and satellite observations. The differences between the present results and those from previous modelling efforts in the region, where few- or multi-layer hydrodynamical models or even fixed-level hydrodynamical models have been employed, are found to be in the same range as the differences among the results from the various sensitivity experiments presented here. This indicates that a small uncertainty in the knowledge of the ecosystem model parameters can be more important in ecosystem modelling than the uncertainty associated to the differences in the vertical coordinate representation of the underlying hydrodynamical model. There are still biological processes, such as denitrification which affect the vertical distribution of nutrient concentrations, that are not included neither in the previous works in the area nor in the present work. This might mask any potential advantages of the present NPZD-MICOM coupled model, especially at mid-depths in the ocean.

  3. Mars 2001 Lander Mission: Measurement Synergy Through Coordinated Operations Planning And Implementation

    NASA Technical Reports Server (NTRS)

    Arvidson, R.; Bell, J. F., III; Kaplan, D.; Marshall, J.; Mishkin, A.; Saunders, S.; Smith, P.; Squyres, S.

    1999-01-01

    , together with quantitative information on material mineralogy, chemistry, and physical properties (rock textures; soil grain size and shape distributions; degree and nature of soil induration; soil magnetic properties). The calibration targets provide radiometric and mineralogical control surfaces. The magnets allow observations of magnetic phases. Patch plates are imaged to determine adhesive and abrasive properties of soils. Coordinated mission planning is crucial for optimizing the measurement synergy among the packages included on the lander. This planning has already begun through generation of multi-sol detailed operations activities. One focus has been to develop a scenario to use the arm to dig a soil trench to a depth of tens of centimeters. The activity will be monitored through use of Pancam and RAC to ensure nominal operations and to acquire data to determine subsurface physical properties (e.g., angle of repose of trench walls). Pancam and Mini-TES observations would also provide constraints on mineralogy and texture for the walls and bottom of the trench during excavation. If desired, soils excavated at depth could be deposited on the surface and Mossbauer and APXS measurements could be acquired for these materials. Soil samples from various depths would be delivered to MECA for characterization of aqueous geochemistry and physical properties of soil grains, particularly size, shape, and hardness. These physical properties would be determined by optical and atomic force microscopy. When completed, detailed information of soil properties as a function of depth would be obtained. These various data sets would constrain our understanding of whether or not there are systematic variations in soil characteristics as a function of depth. These variations might be related, for example, to evaporative moisture losses and formation of salt deposits, thereby indicating water transport processes occurred fairly recently. Many other value-added measurement scenarios are

  4. Interferometer for measuring dynamic corneal topography

    NASA Astrophysics Data System (ADS)

    Micali, Jason Daniel

    The cornea is the anterior most surface of the eye and plays a critical role in vision. A thin fluid layer, the tear film, coats the outer surface of the cornea and serves to protect, nourish, and lubricate the cornea. At the same time, the tear film is responsible for creating a smooth continuous surface where the majority of refraction takes place in the eye. A significant component of vision quality is determined by the shape of the cornea and stability of the tear film. It is desirable to possess an instrument that can measure the corneal shape and tear film surface with the same accuracy and resolution that is currently performed on common optical elements. A dual interferometer system for measuring the dynamic corneal topography is designed, built, and verified. The completed system is validated by testing on human subjects. The system consists of two co-aligned polarization splitting Twyman-Green interferometers designed to measure phase instantaneously. The primary interferometer measures the surface of the tear film while the secondary interferometer simultaneously tracks the absolute position of the cornea. Eye motion, ocular variation, and a dynamic tear film surface will result in a non-null configuration of the surface with respect to the interferometer system. A non-null test results in significant interferometer induced errors that add to the measured phase. New algorithms are developed to recover the absolute surface topography of the tear film and corneal surface from the simultaneous interferometer measurements. The results are high-resolution and high-accuracy surface topography measurements of the in vivo cornea that are captured at standard camera frame rates. This dissertation will cover the development and construction of an interferometer system for measuring the dynamic corneal topography of the human eye. The discussion starts with the completion of an interferometer for measuring the tear film. The tear film interferometer is part of an

  5. Lattice gas dynamics under continuous measurement

    NASA Astrophysics Data System (ADS)

    Patil, Yogesh Sharad; Cheung, Hil F. H.; Madjarov, Ivaylo S.; Chen, Huiyao Y.; Vengalattore, Mukund

    2016-05-01

    The act of measurement has a profound consequences quantum systems. While this backaction has so far been discussed as being a limitation on the precision of measurements, it is increasingly being appreciated that measurement backaction is a powerful and versatile means of quantum control. We have previously demonstrated that backaction from position measurement can modify the coherent tunneling rate of a lattice gas through the Quantum Zeno effect. Here, we show how spatially designed measurement landscapes can be used to realize entropy segregation in lattice gases. This presents an alternate path to the longstanding challenge of realizing lattice gases with sufficiently low entropy to access regimes of correlated quantum behavior such as Néel ordered states. This work is supported by the ARO MURI on non-equilibrium dynamics.

  6. Dynamic Electrochemical Measurement of Chloride Ions.

    PubMed

    Abbas, Yawar; de Graaf, Derk B; Olthuis, Wouter; van den Berg, Albert

    2016-02-05

    This protocol describes the dynamic measurement of chloride ions using the transition time of a silver silver chloride (Ag/AgCl) electrode. Silver silver chloride electrode is used extensively for potentiometric measurement of chloride ions concentration in electrolyte. In this measurement, long-term and continuous monitoring is limited due to the inherent drift and the requirement of a stable reference electrode. We utilized the chronopotentiometric approach to minimize drift and avoid the use of a conventional reference electrode. A galvanostatic pulse is applied to an Ag/AgCl electrode which initiates a faradic reaction depleting the Cl- ions near the electrode surface. The transition time, which is the time to completely deplete the ions near the electrode surface, is a function of the ion concentration, given by the Nernst equation. The square root of the transition time is in linear relation to the chloride ion concentration. Drift of the response over two weeks is negligible (59 µM/day) when measuring 1 mM [Cl-]using a current pulse of 10 Am(-2). This is a dynamic measurement where the moment of transition time determines the response and thus is independent of the absolute potential. Any metal wire can be used as a pseudo-reference electrode, making this approach feasible for long-term measurement inside concrete structures.

  7. Installation and Implementation of an In-Process Coordinate Measuring Machine (CMM)

    SciTech Connect

    Johnston, Derek

    2008-06-16

    This report documents the work accomplished during the installation and implementation of the in-process Coordinate Measuring Machine (CMM) in Department A. A wealth of knowledge has been gained in solving the many technical issues that delayed the partial implementation of this CMM. The work completed thus far lead to the successfully calibrated in-process CMM workstation. A great deal of current and future work has been outlined in the following pages that shall be used as a guide for the full implementation of this CMM with machining processes in Department A.

  8. Psychometric properties of the coordinate response measure corpus with various types of background interferencea)

    PubMed Central

    Eddins, David A.; Liu, Chang

    2012-01-01

    The coordinate response measure (CRM) corpus has gained broad acceptance as a research tool for investigating speech intelligibility in background competition and has been widely used in studies of informational masking. The purpose of this study is to establish the psychometric characteristics of CRM target-word identification in various backgrounds with the goal of being able to determine when it is appropriate or not to use adaptive threshold procedures with the CRM corpus. Target-word identification performance based on adaptive tracking mapped directly onto the monotonic psychometric functions obtained for two-talker, four-talker, and cafeteria noise interferers. PMID:22352619

  9. A new concept of feature-based gauge for coordinate measuring arm evaluation

    NASA Astrophysics Data System (ADS)

    Cuesta, E.; González-Madruga, D.; Alvarez, B. J.; Barreiro, J.

    2014-06-01

    Articulated arm coordinate measuring machines (AACMM or CMA) have conquered a market share in the actual dimensional metrology field, overall when their role implies the inspection of geometrical and dimensional tolerances in an accurate 3D environment for medium-size parts. However, the unavoidable fact of AACMM manual operation constrains its reliability to a great extent, avoiding rigorous evaluation and casting doubt upon the usefulness of external calibration. In this research, a dimensional gauge especially aimed at AACMM evaluation has been developed. Furthermore, the operator skill will be revealed through the use of this gauge. A set of geometrical features, some of them oriented to evaluate the operator and others the equipment, have been collected for the gauge. The proposed evaluation methodology clearly distinguishes between dimensional and geometrical tolerances (with or without datum references), whereas actual verification standards only consider the former. Next, quality indicators deduced from the measurement results are proposed in order to compare AACMM versus coordinate measuring machine (CMM) performance, assuming that CMM possess the maximum accuracy that AACMM could reach, because CMM combines maximum contact accuracy with minimum operator influence. As a result, AACMM evaluation time could be significantly reduced since this gauge allows us to perform a customized evaluation of only those specific tolerances of interest to the user.

  10. Testing coordinate measuring arms with a geometric feature-based gauge: in situ field trials

    NASA Astrophysics Data System (ADS)

    Cuesta, E.; Alvarez, B. J.; Patiño, H.; Telenti, A.; Barreiro, J.

    2016-05-01

    This work describes in detail the definition of a procedure for calibrating and evaluating coordinate measuring arms (AACMMs or CMAs). CMAs are portable coordinate measuring machines that have been widely accepted in industry despite their sensitivity to the skill and experience of the operator in charge of the inspection task. The procedure proposed here is based on the use of a dimensional gauge that incorporates multiple geometric features, specifically designed for evaluating the measuring technique when CMAs are used, at company facilities (workshops or laboratories) and by the usual operators who handle these devices in their daily work. After establishing the procedure and manufacturing the feature-based gauge, the research project was complemented with diverse in situ field tests performed with the collaboration of companies that use these devices in their inspection tasks. Some of the results are presented here, not only comparing different operators but also comparing different companies. The knowledge extracted from these experiments has allowed the procedure to be validated, the defects of the methodologies currently used for in situ inspections to be detected, and substantial improvements for increasing the reliability of these portable instruments to be proposed.

  11. Viscosity measurement techniques in Dissipative Particle Dynamics

    NASA Astrophysics Data System (ADS)

    Boromand, Arman; Jamali, Safa; Maia, Joao M.

    2015-11-01

    In this study two main groups of viscosity measurement techniques are used to measure the viscosity of a simple fluid using Dissipative Particle Dynamics, DPD. In the first method, a microscopic definition of the pressure tensor is used in equilibrium and out of equilibrium to measure the zero-shear viscosity and shear viscosity, respectively. In the second method, a periodic Poiseuille flow and start-up transient shear flow is used and the shear viscosity is obtained from the velocity profiles by a numerical fitting procedure. Using the standard Lees-Edward boundary condition for DPD will result in incorrect velocity profiles at high values of the dissipative parameter. Although this issue was partially addressed in Chatterjee (2007), in this work we present further modifications (Lagrangian approach) to the original LE boundary condition (Eulerian approach) that will fix the deviation from the desired shear rate at high values of the dissipative parameter and decrease the noise to signal ratios in stress measurement while increases the accessible low shear rate window. Also, the thermostat effect of the dissipative and random forces is coupled to the dynamic response of the system and affects the transport properties like the viscosity and diffusion coefficient. We investigated thoroughly the dependency of viscosity measured by both Eulerian and Lagrangian methodologies, as well as numerical fitting procedures and found that all the methods are in quantitative agreement.

  12. Multidimensional characterization of stochastic dynamical systems based on multiple perturbations and measurements

    SciTech Connect

    Kryvohuz, Maksym Mukamel, Shaul

    2015-06-07

    Generalized nonlinear response theory is presented for stochastic dynamical systems. Experiments in which multiple measurements of dynamical quantities are used along with multiple perturbations of parameters of dynamical systems are described by generalized response functions (GRFs). These constitute a new type of multidimensional measures of stochastic dynamics either in the time or the frequency domains. Closed expressions for GRFs in stochastic dynamical systems are derived and compared with numerical non-equilibrium simulations. Several types of perturbations are considered: impulsive and periodic perturbations of temperature and impulsive perturbations of coordinates. The present approach can be used to study various types of stochastic processes ranging from single-molecule conformational dynamics to chemical kinetics of finite-size reactors such as biocells.

  13. Coordinating Multi-Rover Systems: Evaluation Functions for Dynamic and Noisy Environments

    NASA Technical Reports Server (NTRS)

    Turner, Kagan; Agogino, Adrian

    2005-01-01

    This paper addresses the evolution of control strategies for a collective: a set of entities that collectively strives to maximize a global evaluation function that rates the performance of the full system. Directly addressing such problems by having a population of collectives and applying the evolutionary algorithm to that population is appealing, but the search space is prohibitively large in most cases. Instead, we focus on evolving control policies for each member of the collective. The fundamental issue in this approach is how to create an evaluation function for each member of the collective that is both aligned with the global evaluation function and is sensitive to the fitness changes of the member, while relatively insensitive to the fitness changes of other members. We show how to construct evaluation functions in dynamic, noisy and communication-limited collective environments. On a rover coordination problem, a control policy evolved using aligned and member-sensitive evaluations outperfoms global evaluation methods by up to 400%. More notably, in the presence of a larger number of rovers or rovers with noisy and communication limited sensors, the proposed method outperforms global evaluation by a higher percentage than in noise-free conditions with a small number of rovers.

  14. Learning robotic eye-arm-hand coordination from human demonstration: a coupled dynamical systems approach.

    PubMed

    Lukic, Luka; Santos-Victor, José; Billard, Aude

    2014-04-01

    We investigate the role of obstacle avoidance in visually guided reaching and grasping movements. We report on a human study in which subjects performed prehensile motion with obstacle avoidance where the position of the obstacle was systematically varied across trials. These experiments suggest that reaching with obstacle avoidance is organized in a sequential manner, where the obstacle acts as an intermediary target. Furthermore, we demonstrate that the notion of workspace travelled by the hand is embedded explicitly in a forward planning scheme, which is actively involved in detecting obstacles on the way when performing reaching. We find that the gaze proactively coordinates the pattern of eye-arm motion during obstacle avoidance. This study provides also a quantitative assessment of the coupling between the eye-arm-hand motion. We show that the coupling follows regular phase dependencies and is unaltered during obstacle avoidance. These observations provide a basis for the design of a computational model. Our controller extends the coupled dynamical systems framework and provides fast and synchronous control of the eyes, the arm and the hand within a single and compact framework, mimicking similar control system found in humans. We validate our model for visuomotor control of a humanoid robot.

  15. Embodied economics: how bodily information shapes the social coordination dynamics of decision-making

    PubMed Central

    Oullier, Olivier; Basso, Frédéric

    2010-01-01

    To date, experiments in economics are restricted to situations in which individuals are not influenced by the physical presence of other people. In such contexts, interactions remain at an abstract level, agents guessing what another person is thinking or is about to decide based on money exchange. Physical presence and bodily signals are therefore left out of the picture. However, in real life, social interactions (involving economic decisions or not) are not solely determined by a person's inference about someone else's state-of-mind. In this essay, we argue for embodied economics: an approach to neuroeconomics that takes into account how information provided by the entire body and its coordination dynamics influences the way we make economic decisions. Considering the role of embodiment in economics—movements, posture, sensitivity to mimicry and every kind of information the body conveys—makes sense. This is what we claim in this essay which, to some extent, constitutes a plea to consider bodily interactions between agents in social (neuro)economics. PMID:20026467

  16. Embodied economics: how bodily information shapes the social coordination dynamics of decision-making.

    PubMed

    Oullier, Olivier; Basso, Frédéric

    2010-01-27

    To date, experiments in economics are restricted to situations in which individuals are not influenced by the physical presence of other people. In such contexts, interactions remain at an abstract level, agents guessing what another person is thinking or is about to decide based on money exchange. Physical presence and bodily signals are therefore left out of the picture. However, in real life, social interactions (involving economic decisions or not) are not solely determined by a person's inference about someone else's state-of-mind. In this essay, we argue for embodied economics: an approach to neuroeconomics that takes into account how information provided by the entire body and its coordination dynamics influences the way we make economic decisions. Considering the role of embodiment in economics--movements, posture, sensitivity to mimicry and every kind of information the body conveys--makes sense. This is what we claim in this essay which, to some extent, constitutes a plea to consider bodily interactions between agents in social (neuro)economics.

  17. Evolving dynamics of trading behavior based on coordination game in complex networks

    NASA Astrophysics Data System (ADS)

    Bian, Yue-tang; Xu, Lu; Li, Jin-sheng

    2016-05-01

    This work concerns the modeling of evolvement of trading behavior in stock markets. Based on the assumption of the investors' limited rationality, the evolution mechanism of trading behavior is modeled according to the investment strategy of coordination game in network, that investors are prone to imitate their neighbors' activity through comprehensive analysis on the risk dominance degree of certain investment behavior, the network topology of their relationship and its heterogeneity. We investigate by mean-field analysis and extensive simulations the evolution of investors' trading behavior in various typical networks under different risk dominance degree of investment behavior. Our results indicate that the evolution of investors' behavior is affected by the network structure of stock market and the effect of risk dominance degree of investment behavior; the stability of equilibrium states of investors' behavior dynamics is directly related with the risk dominance degree of some behavior; connectivity and heterogeneity of the network plays an important role in the evolution of the investment behavior in stock market.

  18. Optical dynamic deformation measurements at translucent materials.

    PubMed

    Philipp, Katrin; Koukourakis, Nektarios; Kuschmierz, Robert; Leithold, Christoph; Fischer, Andreas; Czarske, Jürgen

    2015-02-15

    Due to their high stiffness-to-weight ratio, glass fiber-reinforced polymers are an attractive material for rotors, e.g., in the aerospace industry. A fundamental understanding of the material behavior requires non-contact, in-situ dynamic deformation measurements. The high surface speeds and particularly the translucence of the material limit the usability of conventional optical measurement techniques. We demonstrate that the laser Doppler distance sensor provides a powerful and reliable tool for monitoring radial expansion at fast rotating translucent materials. We find that backscattering in material volume does not lead to secondary signals as surface scattering results in degradation of the measurement volume inside the translucent medium. This ensures that the acquired signal contains information of the rotor surface only, as long as the sample surface is rough enough. Dynamic deformation measurements of fast-rotating fiber-reinforced polymer composite rotors with surface speeds of more than 300 m/s underline the potential of the laser Doppler sensor.

  19. Compressing measurements in quantum dynamic parameter estimation

    NASA Astrophysics Data System (ADS)

    Magesan, Easwar; Cooper, Alexandre; Cappellaro, Paola

    2013-12-01

    We present methods that can provide an exponential savings in the resources required to perform dynamic parameter estimation using quantum systems. The key idea is to merge classical compressive sensing techniques with quantum control methods to significantly reduce the number of signal coefficients that are required for reconstruction of time-varying parameters with high fidelity. We show that incoherent measurement bases and, more generally, suitable random measurement matrices can be created by performing simple control sequences on the quantum system. Random measurement matrices satisfying the restricted isometry property can be used efficiently to reconstruct signals that are sparse in any basis. Because many physical processes are approximately sparse in some basis, these methods can benefit a variety of applications such as quantum sensing and magnetometry with nitrogen-vacancy centers.

  20. Transfer of learning between unimanual and bimanual rhythmic movement coordination: transfer is a function of the task dynamic.

    PubMed

    Snapp-Childs, Winona; Wilson, Andrew D; Bingham, Geoffrey P

    2015-07-01

    Under certain conditions, learning can transfer from a trained task to an untrained version of that same task. However, it is as yet unclear what those certain conditions are or why learning transfers when it does. Coordinated rhythmic movement is a valuable model system for investigating transfer because we have a model of the underlying task dynamic that includes perceptual coupling between the limbs being coordinated. The model predicts that (1) coordinated rhythmic movements, both bimanual and unimanual, are organised with respect to relative motion information for relative phase in the coupling function, (2) unimanual is less stable than bimanual coordination because the coupling is unidirectional rather than bidirectional, and (3) learning a new coordination is primarily about learning to perceive and use the relevant information which, with equal perceptual improvement due to training, yields equal transfer of learning from bimanual to unimanual coordination and vice versa [but, given prediction (2), the resulting performance is also conditioned by the intrinsic stability of each task]. In the present study, two groups were trained to produce 90° either unimanually or bimanually, respectively, and tested in respect to learning (namely improved performance in the trained 90° coordination task and improved visual discrimination of 90°) and transfer of learning (to the other, untrained 90° coordination task). Both groups improved in the task condition in which they were trained and in their ability to visually discriminate 90°, and this learning transferred to the untrained condition. When scaled by the relative intrinsic stability of each task, transfer levels were found to be equal. The results are discussed in the context of the perception-action approach to learning and performance.

  1. Measuring Displacements in Engineering Structures by Means of a Coordinate Laser Station

    NASA Astrophysics Data System (ADS)

    Sztubecki, Jacek; Bujarkiewicz, Adam; Sztubecka, Małgorzata

    2016-12-01

    The application of geodetic methods to examine structures consists in the determination of their displacements relative to an established geodetic reference datum or in the definition of the geometry of their individual components. Such examinations form a picture of changes happening between specific points in time. Modern measurement technologies used in geodetic engineering enable undertaking more and more challenging measurements with increasing accuracy. The purpose of this article is to present a measurement technique involving a Leica TDRA 6000 total station to measure displacements in engineering structures. The station features a direct drive technology to achieve an accuracy of 0.25 mm in 3-dimensional measurements. Supported by appropriate software, the unit makes a perfect instrument for the monitoring of civil engineering structures. The article presents the results of measurement of static and dynamic displacements in a few engineering structures. The measurements were carried out both in laboratory conditions and on actual, operated civil engineering structures.

  2. Characterization of the volume and shape of quasi-spherical resonators using coordinate measurement machines

    NASA Astrophysics Data System (ADS)

    de Podesta, M.; May, E. F.; Mehl, J. B.; Pitre, L.; Gavioso, R. M.; Benedetto, G.; Giuliano Albo, P. A.; Truong, D.; Flack, D.

    2010-10-01

    Acoustic thermometry using a gas-filled quasi-spherical resonator (QSR) is one of the most promising techniques for measuring the Boltzmann constant kB with low uncertainty. Dimensional metrology with coordinate measurement machines (CMMs) can be used to determine the resonator's volume, either directly or in combination with measurements of the resonator's microwave spectra. We assessed the uncertainty achievable when using a CMM to characterize the shape and volume of three QSRs. The resonators differed significantly in their design and construction: their inner volumes ranged between 524 cm3 and 2225 cm3, while the QSR geometries ranged from a diamond-turned triaxial ellipsoid to the variable misalignment of spheroidal hemispheres. Comparative coordinate measurements of two solid spherical density standards were used to identify and estimate type B uncertainties. We tested the regression of the CMM data to spherical harmonic expansions and determined the volume of a QSR directly with a relative uncertainty uR < 30 parts in 106. Additionally, spherical harmonic regression of the CMM data can place uncertainty bounds on the eccentricity parameters, ε1 and ε2, typically with a relative uncertainty uR ≈ 0.02. This is sufficient to determine corrections to both the acoustic and the microwave resonance frequencies of the QSR with a relative uncertainty uR < 1 part in 106 for all resonances. These figures assume that the enclosed volume of an assembled QSR is equal to the sum of the volumes of its two component 'hemispheres'. In practice this cannot be strictly true and the additional uncertainties in the volume of the assembled QSR are discussed.

  3. Measurement of Gear Tooth Dynamic Friction

    NASA Technical Reports Server (NTRS)

    Rebbechi, Brian; Oswald, Fred B.; Townsend, Dennis P.

    1996-01-01

    Measurements of dynamic friction forces at the gear tooth contact were undertaken using strain gages at the root fillets of two successive teeth. Results are presented from two gear sets over a range of speeds and loads. The results demonstrate that the friction coefficient does not appear to be significantly influenced by the sliding reversal at the pitch point, and that the friction coefficient values found are in accord with those in general use. The friction coefficient was found to increase at low sliding speeds. This agrees with the results of disc machine testing.

  4. Orthogonal coordinates for the dynamics of four bodies and for the representation of potentials of tetra-atomic molecules

    NASA Astrophysics Data System (ADS)

    Ragni, Mirco; Bitencourt, Ana Carla P.; Aquilanti, Vincenzo

    We discuss systems of orthogonal coordinates for the dynamical treatment of four particles, generated by making extensive use of the concept of kinematic rotations, which act on coordinates of the particles and are represented by matrices only dependent on their masses. The explicit representations of the kinetic rotation matrices are given: this allows us to define alternative particle schemes, such as those based on the Jacobi and Radau-Smith vectors, as well as on mixed types of vectors, of possible interest for specific molecules or aggregates. A list is given of relevant formulas connecting these coordinate sets to the geometrical parameters (internuclear distances, bond and dihedral angles) of use for the representation of the potential energy surface of four atomic systems. Applications are indicated for molecular and cluster physics.0

  5. A portable instrument for 3-D dynamic robot measurements using triangulation and laser tracking

    SciTech Connect

    Mayer, J.R.R. . Mechanical Engineering Dept.); Parker, G.A. . Dept. of Mechanical Engineering)

    1994-08-01

    The paper describes the development and validation of a 3-D measurement instrument capable of determining the static and dynamic performance of industrial robots to ISO standards. Using two laser beams to track an optical target attached to the robot end-effector, the target position coordinates may be estimated, relative to the instrument coordinate frame, to a high accuracy using triangulation principles. The effect of variations in the instrument geometry from the nominal model is evaluated through a kinematic model of the tracking head. Significant improvements of the measurement accuracy are then obtained by a simple adjustment of the main parameters. Extensive experimental test results are included to demonstrate the instrument performance. Finally typical static and dynamic measurement results for an industrial robot are presented to illustrate the effectiveness and usefulness of the instrument.

  6. Coordinated measurements made by the Sondrestrom radar and the Polar Bear ultraviolet imager

    SciTech Connect

    Robinson, R.; Vondrak, R. ); Dabbs, T.; Vickrey, J. ); Eastes, R.; Del Greco, F.; Huffman, R. ); Meng, C. ); Daniell, R.; Strickland, D.; Vondrak, R. )

    1992-03-01

    In 1986 and 1987 the Sondrestrom incoherent scatter radar in Greenland was operated routinely in coordination with selected overpasses of the Polar Bear satellite. For these experiments the auroral ionospheric remote sensor on Polar Bear obtained images of auroral emissions in two far ultraviolet wavelength bands centered at approximately 136 and 160 nm and one visible band centered at 391.4 nm. Measurements at these three wavelengths were extracted from the images for comparison with the coincident radar measurements. Model calculations have shown that for Maxwellian incident electron distributions the ratio between the 136-nm luminosity and 391.4-nm luminosity can be used to estimate the mean energy of precipitating electrons. Once the mean energy is known, then either of the two emissions can be used to determine the total energy flux. This procedure is used to determine the properties of the incident electron distribution during three midnight sector auroral events over Sondre Stromfjord. The incident electron flux is then used to calculate the expected height profile of electron density which is compared with the simultaneous and coincident radar measurements. The results show that the derived profiles agree well with the measured profiles both in the peak electron density and the altitude of the peak. The accuracy with which the peak of the profile is predicted by this technique is such that many important ionospheric parameters can be reliably inferred from remote measurements, including, for example, the height-integrated electrical conductivities.

  7. Embodiment of intersubjective time: relational dynamics as attractors in the temporal coordination of interpersonal behaviors and experiences

    PubMed Central

    Laroche, Julien; Berardi, Anna Maria; Brangier, Eric

    2014-01-01

    This paper addresses the issue of “being together,” and more specifically the issue of “being together in time.” We provide with an integrative framework that is inspired by phenomenology, the enactive approach and dynamical systems theories. To do so, we first define embodiment as a living and lived phenomenon that emerges from agent-world coupling. We then show that embodiment is essentially dynamical and therefore we describe experiential, behavioral and brain dynamics. Both lived temporality and the temporality of the living appear to be complex, multiscale phenomena. Next we discuss embodied dynamics in the context of interpersonal interactions, and briefly review the empirical literature on between-persons temporal coordination. Overall, we propose that being together in time emerges from the relational dynamics of embodied interactions and their flexible co-regulation. PMID:25400598

  8. Kriging-Based Parameter Estimation Algorithm for Metabolic Networks Combined with Single-Dimensional Optimization and Dynamic Coordinate Perturbation.

    PubMed

    Wang, Hong; Wang, Xicheng; Li, Zheng; Li, Keqiu

    2016-01-01

    The metabolic network model allows for an in-depth insight into the molecular mechanism of a particular organism. Because most parameters of the metabolic network cannot be directly measured, they must be estimated by using optimization algorithms. However, three characteristics of the metabolic network model, i.e., high nonlinearity, large amount parameters, and huge variation scopes of parameters, restrict the application of many traditional optimization algorithms. As a result, there is a growing demand to develop efficient optimization approaches to address this complex problem. In this paper, a Kriging-based algorithm aiming at parameter estimation is presented for constructing the metabolic networks. In the algorithm, a new infill sampling criterion, named expected improvement and mutual information (EI&MI), is adopted to improve the modeling accuracy by selecting multiple new sample points at each cycle, and the domain decomposition strategy based on the principal component analysis is introduced to save computing time. Meanwhile, the convergence speed is accelerated by combining a single-dimensional optimization method with the dynamic coordinate perturbation strategy when determining the new sample points. Finally, the algorithm is applied to the arachidonic acid metabolic network to estimate its parameters. The obtained results demonstrate the effectiveness of the proposed algorithm in getting precise parameter values under a limited number of iterations.

  9. Atomic Quadrupole Moment Measurement Using Dynamic Decoupling.

    PubMed

    Shaniv, R; Akerman, N; Ozeri, R

    2016-04-08

    We present a method that uses dynamic decoupling of a multilevel quantum probe to distinguish small frequency shifts that depend on m_{j}^{2}, where m_{j}^{2} is the angular momentum of level |j⟩ along the quantization axis, from large noisy shifts that are linear in m_{j}, such as those due to magnetic field noise. Using this method we measured the electric-quadrupole moment of the 4D_{5/2} level in ^{88}Sr^{+} to be 2.973_{-0.033}^{+0.026}ea_{0}^{2}. Our measurement improves the uncertainty of this value by an order of magnitude and thus helps mitigate an important systematic uncertainty in ^{88}Sr^{+} based optical atomic clocks and verifies complicated many-body quantum calculations.

  10. Coordination properties of a metal chelator clioquinol to Zn(2+) studied by static DFT and ab initio molecular dynamics.

    PubMed

    Rodríguez-Santiago, Luis; Alí-Torres, Jorge; Vidossich, Pietro; Sodupe, Mariona

    2015-05-28

    Several lines of evidence supporting the role of metal ions in amyloid aggregation, one of the hallmarks of Alzheimer's disease (AD), have turned metal ion chelation into a promising therapeutic treatment. The design of efficient chelating ligands requires proper knowledge of the electronic and molecular structure of the complexes formed, including their hydration properties. Among various potential chelators, clioquinol (5-chloro-7-iodo-8-hydroxyquinoline, CQH) has been evaluated with relative success in in vitro experiments and even in phase 2 clinical trials. Clioquinol interacts with Zn(ii) to lead to a binary metal/ligand 1 : 2 stoichiometric complex in which the phenolic group of CQH is deprotonated, resulting in Zn(CQ)2 neutral complexes, to which additional water molecules may coordinate. In the present work, the coordinative properties of clioquinol in aqueous solution have been analyzed by means of static, minimal cluster based DFT calculations and explicit solvent ab initio molecular dynamics simulations. Results from static calculations accounting for solvent effects by means of polarized continuum models suggest that the preferred metal coordination environment is tetrahedral Zn(CQ)2, whereas ab initio molecular dynamics simulations point to quasi degenerate penta Zn(CQ)2(H2O) and hexa Zn(CQ)2(H2O)2 coordinated complexes. The possible reasons for these discrepant results are discussed.

  11. Coordination and hydrolysis of plutonium ions in aqueous solution using Car-Parrinello molecular dynamics free energy simulations.

    PubMed

    Odoh, Samuel O; Bylaska, Eric J; de Jong, Wibe A

    2013-11-27

    Car-Parrinello molecular dynamics (CPMD) simulations have been used to examine the hydration structures, coordination energetics, and the first hydrolysis constants of Pu(3+), Pu(4+), PuO2(+), and PuO2(2+) ions in aqueous solution at 300 K. The coordination numbers and structural properties of the first shell of these ions are in good agreement with available experimental estimates. The hexavalent PuO2(2+) species is coordinated to five aquo ligands while the pentavalent PuO2(+) complex is coordinated to four aquo ligands. The Pu(3+) and Pu(4+) ions are both coordinated to eight water molecules. The first hydrolysis constants obtained for Pu(3+) and PuO2(2+) are 6.65 and 5.70, respectively, all within 0.3 pH unit of the experimental values (6.90 and 5.50, respectively). The hydrolysis constant of Pu(4+), 0.17, disagrees with the value of -0.60 in the most recent update of the Nuclear Energy Agency Thermochemical Database (NEA-TDB) but supports recent experimental findings. The hydrolysis constant of PuO2(+), 9.51, supports the experimental results of Bennett et al. [Radiochim. Acta 1992, 56, 15]. A correlation between the pKa of the first hydrolysis reaction and the effective charge of the plutonium center was found.

  12. Coordination and Hydrolysis of Plutonium Ions in Aqueous Solution using Car-Parrinello Molecular Dynamics Free Energy Simulations

    SciTech Connect

    Odoh, Samuel O.; Bylaska, Eric J.; De Jong, Wibe A.

    2013-11-27

    Car-Parrinello molecular dynamics (CPMD) simulations have been used to examine the hydration structures, coordination energetics and the first hydrolysis constants of Pu3+, Pu4+, PuO2+ and PuO22+ ions in aqueous solution at 300 K. The coordination numbers and structural properties of the first shell of these ions are in good agreement with available experimental estimates. The hexavalent PuO22+ species is coordinated to 5 aquo ligands while the pentavalent PuO2+ complex is coordinated to 4 aquo ligands. The Pu3+ and Pu4+ ions are both coordinated to 8 water molecules. The first hydrolysis constants obtained for Pu3+ and PuO22+ are 6.65 and 5.70 respectively, all within 0.3 pH units of the experimental values (6.90 and 5.50 respectively). The hydrolysis constant of Pu4+, 0.17, disagrees with the value of -0.60 in the most recent update of the Nuclear Energy Agency Thermochemical Database (NEA-TDB) but supports recent experimental findings. The hydrolysis constant of PuO2+, 9.51, supports the experimental results of Bennett et al. (Radiochim. Act. 1992, 56, 15). A correlation between the pKa of the first hydrolysis reaction and the effective charge of the plutonium center was found.

  13. Non-coincident Inter-instrument Comparisons of Ozone Measurements Using Quasi-conservative Coordinates

    NASA Technical Reports Server (NTRS)

    Lait, L. R.; Newman, P. A.; Schoeberl, M. R.; McGee, T.; Twigg, T.; Browell, E.; Bevilacqua, R.; Andersen, S. B.; DeBacker, H.; Benesova, A.

    2004-01-01

    Ozone measurements from ozonesondes, AROTAL, DIAL, and POAM III instruments during the SOLVE-2/VINTERSOL period are composited in a time-varying, flow-following quasi-conservative (PV-6) coordinate space; the resulting composites from each instrument are mapped onto the other instruments locations and times. The mapped data are then used to intercompare data from the different instruments. Overall, the four data sets are found to be in good agreement. AROTAL shows somewhat lower values below 16 km, and DIAL has a positive bias at the upper limits of its altitude range. These intercomparisons are consistent with those obtained from more conventional near-coincident profiles, where available. Although the PV-theta mapping technique entails larger uncertainties of individual profile differences compared to direct near-coincident comparisons, the ability to include much larger numbers of comparisons can make this technique advantageous.

  14. Studying the role of protein dynamics in an SN2 enzyme reaction using free-energy surfaces and solvent coordinates.

    PubMed

    García-Meseguer, Rafael; Martí, Sergio; Ruiz-Pernía, J Javier; Moliner, Vicent; Tuñón, Iñaki

    2013-07-01

    Conformational changes are known to be able to drive an enzyme through its catalytic cycle, allowing, for example, substrate binding or product release. However, the influence of protein motions on the chemical step is a controversial issue. One proposal is that the simple equilibrium fluctuations incorporated into transition-state theory are insufficient to account for the catalytic effect of enzymes and that protein motions should be treated dynamically. Here, we propose the use of free-energy surfaces, obtained as a function of both a chemical coordinate and an environmental coordinate, as an efficient way to elucidate the role of protein structure and motions during the reaction. We show that the structure of the protein provides an adequate environment for the progress of the reaction, although a certain degree of flexibility is needed to attain the full catalytic effect. However, these motions do not introduce significant dynamical corrections to the rate constant and can be described as equilibrium fluctuations.

  15. Studying the role of protein dynamics in an SN2 enzyme reaction using free-energy surfaces and solvent coordinates

    NASA Astrophysics Data System (ADS)

    García-Meseguer, Rafael; Martí, Sergio; Ruiz-Pernía, J. Javier; Moliner, Vicent; Tuñón, Iñaki

    2013-07-01

    Conformational changes are known to be able to drive an enzyme through its catalytic cycle, allowing, for example, substrate binding or product release. However, the influence of protein motions on the chemical step is a controversial issue. One proposal is that the simple equilibrium fluctuations incorporated into transition-state theory are insufficient to account for the catalytic effect of enzymes and that protein motions should be treated dynamically. Here, we propose the use of free-energy surfaces, obtained as a function of both a chemical coordinate and an environmental coordinate, as an efficient way to elucidate the role of protein structure and motions during the reaction. We show that the structure of the protein provides an adequate environment for the progress of the reaction, although a certain degree of flexibility is needed to attain the full catalytic effect. However, these motions do not introduce significant dynamical corrections to the rate constant and can be described as equilibrium fluctuations.

  16. Dynamic neurotransmitter interactions measured with PET

    SciTech Connect

    Schiffer, W.K.; Dewey, S.L.

    2001-04-02

    Positron emission tomography (PET) has become a valuable interdisciplinary tool for understanding physiological, biochemical and pharmacological functions at a molecular level in living humans, whether in a healthy or diseased state. The utility of tracing chemical activity through the body transcends the fields of cardiology, oncology, neurology and psychiatry. In this, PET techniques span radiochemistry and radiopharmaceutical development to instrumentation, image analysis, anatomy and modeling. PET has made substantial contributions in each of these fields by providing a,venue for mapping dynamic functions of healthy and unhealthy human anatomy. As diverse as the disciplines it bridges, PET has provided insight into an equally significant variety of psychiatric disorders. Using the unique quantitative ability of PET, researchers are now better able to non-invasively characterize normally occurring neurotransmitter interactions in the brain. With the knowledge that these interactions provide the fundamental basis for brain response, many investigators have recently focused their efforts on an examination of the communication between these chemicals in both healthy volunteers and individuals suffering from diseases classically defined as neurotransmitter specific in nature. In addition, PET can measure the biochemical dynamics of acute and sustained drug abuse. Thus, PET studies of neurotransmitter interactions enable investigators to describe a multitude of specific functional interactions in the human brain. This information can then be applied to understanding side effects that occur in response to acute and chronic drug therapy, and to designing new drugs that target multiple systems as opposed to single receptor types. Knowledge derived from PET studies can be applied to drug discovery, research and development (for review, see (Fowler et al., 1999) and (Burns et al., 1999)). Here, we will cover the most substantial contributions of PET to understanding

  17. Measurements and analysis of end-to-end Internet dynamics

    SciTech Connect

    Paxson, Vern

    1997-04-01

    Accurately characterizing end-to-end Internet dynamics - the performance that a user actually obtains from the lengthy series of network links that comprise a path through the Internet - is exceptionally difficult, due to the network`s immense heterogeneity. At the heart of this work is a `measurement framework` in which a number of sites around the Internet host a specialized measurement service. By coordinating `probes` between pairs of these sites one can measure end-to-end behavior along O(N2) paths for a framework consisting of N sites. Consequently, one obtains a superlinear scaling that allows measuring a rich cross-section of Internet behavior without requiring huge numbers of observation points. 37 sites participated in this study, allowing the author to measure more than 1,000 distinct Internet paths. The first part of this work looks at the behavior of end-to-end routing: the series of routers over which a connection`s packets travel. Based on 40,000 measurements made using this framework, the author analyzes: routing `pathologies` such as loops, outages, and flutter; the stability of routes over time; and the symmetry of routing along the two directions of an end-to-end path. The author finds that pathologies increased significantly over the course of 1995 and that Internet paths are heavily dominated by a single route. The second part of this work studies end-to-end Internet packet dynamics. The author analyzes 20,000 TCP transfers of 100 Kbyte each to investigate the performance of both the TCP endpoints and the Internet paths. The measurements used for this part of the study are much richer than those for the first part, but require a great degree of attention to issues of calibration, which are addressed by applying self-consistency checks to the measurements whenever possible. The author finds that packet filters are capable of a wide range of measurement errors, some of which, if undetected, can significantly taint subsequent analysis.

  18. Hawking Radiation and Entropy of a Dynamic Dilaton-Maxwell Black Hole with a New Tortoise Coordinate Transformation

    NASA Astrophysics Data System (ADS)

    Lan, Xiao-Gang

    2013-05-01

    By introducing a new tortoise coordinate transformation, we apply Damour-Ruffini-Sannan method to study the Hawking radiation of massive scalar particles in a dynamic Dilaton-Maxwell black hole. We find that Hawking radiation spectrum shows still the blackbody one, while the Hawking temperature is significantly changed. Additionally, by adopting the thin film method, we calculate the entropy of a dynamic Dilaton-Maxwell black hole. The result indicates that the entropy for such a black hole is still in proportional to the area of its event horizon.

  19. Using a coordinate measuring machine to calibrate step gages at world class levels of uncertainty

    SciTech Connect

    Zurcher, N.

    1996-08-01

    The purpose of this paper is to relate some of the experiences of using a coordinate measuring machine (CMM) to calibrate long end standards and step gages at measurement uncertainties of less than 0. 5{mu}m. It is not the intent of this paper to suggest that everyone should return to his or her laboratory and change the way CMMs are operated nor to suggest that the methods discussed here are even the best methods. The intent is to provide some food for thought, based on real experiences, about the use of a CMM to measure at low levels of uncertainty. As will become apparent, a lot of the issues discussed really apply to any dimensional measuring technique operating at low levels of uncertainty, not just a CMM. The discussion in this paper is based on measuring one-dimensional end standards and step gages placed along the x-axis of the Moore M-60 CMM located at the Oak Ridge Metrology Center, which is part of the Oak Ridge Centers for Manufacturing Technology at the Y-12 Plant (formerly used in manufacturing nuclear weapons parts) in Oak Ridge, Tennessee. When the Cold War ended, the U.S. Department of Energy (DOE) pushed to make nuclear weapons technology available to U.S. industry. As part of this technology transfer effort, it was determined that the M-60 could be used by the National Institute of Standards and Technology (NIST) to provide a calibration service for step gages. Previously, U.S. industrialists had to go to Germany for step gage calibrations at the lowest levels of measurement uncertainty. Much of the discussion that follows is based on the process developed to use the M-60 for the NIST calibration.

  20. A PLM-based automated inspection planning system for coordinate measuring machine

    NASA Astrophysics Data System (ADS)

    Zhao, Haibin; Wang, Junying; Wang, Boxiong; Wang, Jianmei; Chen, Huacheng

    2006-11-01

    With rapid progress of Product Lifecycle Management (PLM) in manufacturing industry, automatic generation of inspection planning of product and the integration with other activities in product lifecycle play important roles in quality control. But the techniques for these purposes are laggard comparing with techniques of CAD/CAM. Therefore, an automatic inspection planning system for Coordinate Measuring Machine (CMM) was developed to improve the automatization of measuring based on the integration of inspection system in PLM. Feature information representation is achieved based on a PLM canter database; measuring strategy is optimized through the integration of multi-sensors; reasonable number and distribution of inspection points are calculated and designed with the guidance of statistic theory and a synthesis distribution algorithm; a collision avoidance method is proposed to generate non-collision inspection path with high efficiency. Information mapping is performed between Neutral Interchange Files (NIFs), such as STEP, DML, DMIS, XML, etc., to realize information integration with other activities in the product lifecycle like design, manufacturing and inspection execution, etc. Simulation was carried out to demonstrate the feasibility of the proposed system. As a result, the inspection process is becoming simpler and good result can be got based on the integration in PLM.

  1. Stream-potential formulation of atmospheric dynamics in pressure-related coordinates

    NASA Astrophysics Data System (ADS)

    Rõõm, Rein

    2014-05-01

    Departing from non-hydrostatic covariant equations of motion (1) in isobaric coordinates [1]: δv-= F, v = {dx /dt,dy/dt,dp/dt} = {vx,vy,vp} = {u,v,ω} δt (1) equations of motion for 3D velocity divergence ξ0 and curl ξ are derived 0 δξ- = downtriangle·F, δξ-= downtriangle ×F, ξ0 = downtriangle ·v = δαv α, ξ = downtriangle ×v leftrightarrow ξi = ɛiαβδαvβ δt δt (2) Presenting 3D-velocity v in terms of 4D stream-potential {ψ0,ψx,ψy,ψp} 0 i iα 0 αβγ v = downtriangle ψ + downtriangle × ψ leftrightarrow v = G δα ψ + ɛ δβψγ, where Gij is the metric tensor of pressure (p) or hybrid (η) curved space, subsequent application of div and curl to v yields elliptic equations for {ψ0,ψx,ψy,ψp} ( ) L0ψ0 = ξ0, Liαψα = ξj,L0 = δαG αβδβ, Lij = δα GiαG βj - GiβGαj δβ (3) In native pressure coordinates or for low orography, when G becomes diagonal with main elements 11 22 33 2 2 G = G = 1, G = p /H , (H = RT /g istheheightscale) system (3) can be reduced to three independent equations (4) for three fields - scalar flow potential ψ0, horizontal divergence Ξ = δxψx + δyψy of stream function and vertical pessure-velocity ω = δxψy - δyψx ≠¡ dp/dt: ( ) p2 p2 δ2 p2 δ2 L0ψ0 = ξ0, L0Ξ = δp p2ξp/H2 ,Lω = H2- (δyξx - δxξy)L0 = H2-δp2+ downtriangle2, L = H2-δp2+downtriangle2. (4) As the velocity v is specified by the triplet ω,Ξ,ψ0, in full, Eqs. (2) and (4) represent alternate to (1) equations of motion and constitute along with the scale-height (temperature) and surface pressure equations dH R H ω RQ δps δ« ps -dt = c-p- + -g-, δt- = downtriangle · vdp p 0 (5) a complete set for non-hydrostatic modelling of atmospheric dynamics. Equations for ξ0,ψ0,ps represent the 'acoustic loop', which withdraws to the external wave equation for surface pressure fluctuation at slow quasi-hydrostatic motion limit (QHL: ψ0 → 0). Equations for ξ,Ξ,ω,H constitute a non-linear, third

  2. Dynamic plasmapause model based on THEMIS measurements

    NASA Astrophysics Data System (ADS)

    Liu, W.; Liu, X.

    2015-12-01

    We will present a dynamic plasmapause location model established based on five years of THEMIS measurements from 2009 to 2013. In total, 5878 plasmapause crossing events are identified, sufficiently covering all 24 Magnetic Local Time (MLT) sectors. Based on this plasmapause crossing database, we investigate the correlations between plasmapause locations with solar wind parameters and geomagnetic indices. Input parameters for the best fits are obtained for different MLT sectors and finally we choose five input parameters to build a plasmapause location model, including five-minute-averaged SYM-H, AL and AU indices as well as hourly-averaged AE and Kp indices. An out-of-sample comparison on the evolution of the plasmapause is shown during April 2001 magnetic storm, demonstrating good agreement between model results and observations. Two major advantages are achieved by this model. First, this model provides plasmapause locations at 24 MLT sectors, still providing good consistency with observations. Second, this model is able to reproduce dynamic variations of plasmapause in the time scale as short as five minutes.

  3. Detection of subtle dynamical changes induced by unresolved "conformational coordinates" in single-molecule trajectories via goodness-of-fit tests.

    PubMed

    Calderon, Christopher P

    2010-03-11

    Single-molecule experiments are allowing researchers to track the evolution of a few order parameters characterizing complex biomolecules. At fine temporal resolution, artifacts of unresolved degrees of freedom, for example, those induced by collective molecular motion, often influence the dynamics. Reliably detecting subtle changes in dynamics at the nanoscale can be difficult due to the inherent stochasticity, but such changes can have relevance to understanding complex enzyme kinetics. Surrogate models can be used to summarize the information content in single-molecule time series (containing fluctuations occurring over multiple time scales). The focus in this article is on detecting slow time scale changes through the use of the surrogates. The conditional density, associated with the surrogates, allows one to formulate quantitative hypothesis tests which can detect the influence of unresolved coordinates in cases where the dynamics are modulated subtly. The relevance of quantitative (and appropriate) testing methods to analyze single-molecule time series is discussed and demonstrated. A brief discussion on some merits of using frequentist (versus Bayesian) time series methods to analyze single-molecule data is also presented. Idealized simulations mimicking features relevant to some enzyme systems where an "unresolved conformational coordinate" slowly evolves (1) with inertia and (2) diffusively are studied in the nonstationary (nonergodic) setting; however, the findings are also relevant to experimentally measured time series and stationary signals.

  4. The dynamics of information-driven coordination phenomena: A transfer entropy analysis

    PubMed Central

    Borge-Holthoefer, Javier; Perra, Nicola; Gonçalves, Bruno; González-Bailón, Sandra; Arenas, Alex; Moreno, Yamir; Vespignani, Alessandro

    2016-01-01

    Data from social media provide unprecedented opportunities to investigate the processes that govern the dynamics of collective social phenomena. We consider an information theoretical approach to define and measure the temporal and structural signatures typical of collective social events as they arise and gain prominence. We use the symbolic transfer entropy analysis of microblogging time series to extract directed networks of influence among geolocalized subunits in social systems. This methodology captures the emergence of system-level dynamics close to the onset of socially relevant collective phenomena. The framework is validated against a detailed empirical analysis of five case studies. In particular, we identify a change in the characteristic time scale of the information transfer that flags the onset of information-driven collective phenomena. Furthermore, our approach identifies an order-disorder transition in the directed network of influence between social subunits. In the absence of clear exogenous driving, social collective phenomena can be represented as endogenously driven structural transitions of the information transfer network. This study provides results that can help define models and predictive algorithms for the analysis of societal events based on open source data. PMID:27051875

  5. Results of error correction techniques applied on two high accuracy coordinate measuring machines

    SciTech Connect

    Pace, C.; Doiron, T.; Stieren, D.; Borchardt, B.; Veale, R.; National Inst. of Standards and Technology, Gaithersburg, MD )

    1990-01-01

    The Primary Standards Laboratory at Sandia National Laboratories (SNL) and the Precision Engineering Division at the National Institute of Standards and Technology (NIST) are in the process of implementing software error correction on two nearly identical high-accuracy coordinate measuring machines (CMMs). Both machines are Moore Special Tool Company M-48 CMMs which are fitted with laser positioning transducers. Although both machines were manufactured to high tolerance levels, the overall volumetric accuracy was insufficient for calibrating standards to the levels both laboratories require. The error mapping procedure was developed at NIST in the mid 1970's on an earlier but similar model. The error mapping procedure was originally very complicated and did not make any assumptions about the rigidness of the machine as it moved, each of the possible error motions was measured at each point of the error map independently. A simpler mapping procedure was developed during the early 1980's which assumed rigid body motion of the machine. This method has been used to calibrate lower accuracy machines with a high degree of success and similar software correction schemes have been implemented by many CMM manufacturers. The rigid body model has not yet been used on highly repeatable CMMs such as the M48. In this report we present early mapping data for the two M48 CMMs. The SNL CMM was manufactured in 1985 and has been in service for approximately four years, whereas the NIST CMM was delivered in early 1989. 4 refs., 5 figs.

  6. Movement Characteristics Analysis and Dynamic Simulation of Collaborative Measuring Robot

    NASA Astrophysics Data System (ADS)

    guoqing, MA; li, LIU; zhenglin, YU; guohua, CAO; yanbin, ZHENG

    2017-03-01

    Human-machine collaboration is becoming increasingly more necessary, and so collaborative robot applications are also in high demand. We selected a UR10 robot as our research subject for this study. First, we applied D-H coordinate transformation of the robot to establish a link system, and we then used inverse transformation to solve the robot’s inverse kinematics and find all the joints. Use Lagrange method to analysis UR robot dynamics; use ADAMS multibody dynamics simulation software to dynamic simulation; verifying the correctness of the derived kinetic models.

  7. Aging induced loss of complexity and dedifferentiation: consequences for coordination dynamics within and between brain, muscular and behavioral levels

    PubMed Central

    Sleimen-Malkoun, Rita; Temprado, Jean-Jacques; Hong, S. Lee

    2014-01-01

    Growing evidence demonstrates that aging not only leads to structural and functional alterations of individual components of the neuro-musculo-skeletal system (NMSS) but also results in a systemic re-organization of interactions within and between the different levels and functional domains. Understanding the principles that drive the dynamics of these re-organizations is an important challenge for aging research. The present Hypothesis and Theory paper is a contribution in this direction. We propose that age-related declines in brain and behavior that have been characterized in the literature as dedifferentiation and the loss of complexity (LOC) are: (i) synonymous; and (ii) integrated. We argue that a causal link between the aforementioned phenomena exists, evident in the dynamic changes occurring in the aging NMSS. Through models and methods provided by a dynamical systems approach to coordination processes in complex living systems, we: (i) formalize operational hypotheses about the general principles of changes in cross-level and cross-domain interactions during aging; and (ii) develop a theory of the aging NMSS based on the combination of the frameworks of coordination dynamics (CD), dedifferentiation, and LOC. Finally, we provide operational predictions in the study of aging at neural, muscular, and behavioral levels, which lead to testable hypotheses and an experimental agenda to explore the link between CD, LOC and dedifferentiation within and between these different levels. PMID:25018731

  8. Crystalline coordination framework endowed with dynamic gate-opening behaviour by being downsized to a thin film

    NASA Astrophysics Data System (ADS)

    Sakaida, Shun; Otsubo, Kazuya; Sakata, Osami; Song, Chulho; Fujiwara, Akihiko; Takata, Masaki; Kitagawa, Hiroshi

    2016-04-01

    The fabrication of porous coordination frameworks in thin-film forms has been investigated intensively with a view to using their structural response to external stimuli and guests for potential nanotechnological applications, for example as membranes for gas separation. Here we report a coordination framework that exhibits a dynamic guest-sorption behaviour in a nanometre-sized thin-film form (16 nm thick), yet shows no guest uptake in the bulk. Highly oriented crystalline thin films of this coordination framework—which consists of interdigitated two-dimensional layers of {Fe(py)2[Pt(CN)4]} (py, pyridine)—were fabricated through liquid-phase layer-by-layer synthesis. The resulting thin film exhibited a clear guest uptake with a structural transformation of the gate-opening type as characterized by in situ X-ray diffraction. Increasing the film's thickness markedly suppressed this behaviour. We envisage that such a crystal-downsizing effect may be observed with other coordination frameworks, and may be of use to develop functional materials, for example, for switching or sensing devices.

  9. Combining radial basis function surrogates and dynamic coordinate search in high-dimensional expensive black-box optimization

    NASA Astrophysics Data System (ADS)

    Regis, Rommel G.; Shoemaker, Christine A.

    2013-05-01

    This article presents the DYCORS (DYnamic COordinate search using Response Surface models) framework for surrogate-based optimization of HEB (High-dimensional, Expensive, and Black-box) functions that incorporates an idea from the DDS (Dynamically Dimensioned Search) algorithm. The iterate is selected from random trial solutions obtained by perturbing only a subset of the coordinates of the current best solution. Moreover, the probability of perturbing a coordinate decreases as the algorithm reaches the computational budget. Two DYCORS algorithms that use RBF (Radial Basis Function) surrogates are developed: DYCORS-LMSRBF is a modification of the LMSRBF algorithm while DYCORS-DDSRBF is an RBF-assisted DDS. Numerical results on a 14-D watershed calibration problem and on eleven 30-D and 200-D test problems show that DYCORS algorithms are generally better than EGO, DDS, LMSRBF, MADS with kriging, SQP, an RBF-assisted evolution strategy, and a genetic algorithm. Hence, DYCORS is a promising approach for watershed calibration and for HEB optimization.

  10. Information Contents of a Signal at Repeated Positioning Measurements of the Coordinate Measuring Machine (CMM) by Laser Interferometer

    NASA Astrophysics Data System (ADS)

    Stejskal, Tomáš; Kelemenová, Tatiana; Dovica, Miroslav; Demeč, Peter; Štofa, Miroslav

    2016-10-01

    The input of this paper lies in displaying possibilities how to determine the condition of a coordinate measuring machine (CMM) based on a large number of repeated measurements. The number of repeated measurements exceeds common requirements for determining positioning accuracy. The total offset in the accuracy of spatial positioning consists of partial inaccuracies of individual axes. 6 basic errors may be defined at each axis. In a triaxial set, that translates into 18 errors, to which an offset from the perpendicularity between the axial pairs must be added. Therefore, the combined number of errors in a single position is 21. These errors are systemic and stem from the machine's geometry. In addition, there are accidental errors to account for as well. Accidental errors can be attributed to vibrations, mass inertness, passive resistance, and in part to fluctuations in temperature. A peculiar set of systemic errors are time-varying errors. The nature of those errors may be reversible, for instance if they result from influence of temperature or elastic deformation. They can be also irreversible, for example as a result of wear and tear or line clogging, due to loosened connection or permanent deformation of a part post collision. A demonstration of thermal equalizing of the machine's parts may also be observed in case of failure to adhere to a sufficient time interval from the moment the air-conditioning is turned on. Repeated measurements done on a selected axis with linear interferometer can provide complex information on the CMM condition and also on the machine's interaction with the given technical environment.

  11. Application of standard and advanced open source GIS software functionality for analysis of coordinates obtained by GNSS measurements

    NASA Astrophysics Data System (ADS)

    Ilieva, Tamara

    2016-04-01

    Currently there is wide variety of GNSS measurements used in the geodetic practice. The coordinates obtained by static, kinematic or precise point positioning GNSS measurements could be analyzed by using the standard functionality of any GIS software, but the open source ones give to the users an opportunity to make themselves advanced functionality. There is an option the coordinates obtained by measurements to be stored in spatial geodatabase and information for the precision and time of measurement to be added. The data could be visualized in different coordinate systems and projections and analyzed by applying different types of spatial analysis. The process also could be automated in high degree. An example with test data is prepared. It includes automated loading of files with coordinates obtained by GNSS measurements and additional information for the precision and the time of measurements. Standard and advanced open source GIS software functionality is used for automation of the analysis process. Also, graph theory is implemented for making time series of the data stored in the spatial geodatabase.

  12. Review and Evaluation of Hand–Arm Coordinate Systems for Measuring Vibration Exposure, Biodynamic Responses, and Hand Forces

    PubMed Central

    Dong, Ren G.; Sinsel, Erik W.; Welcome, Daniel E.; Warren, Christopher; Xu, Xueyan S.; McDowell, Thomas W.; Wu, John Z.

    2015-01-01

    The hand coordinate systems for measuring vibration exposures and biodynamic responses have been standardized, but they are not actually used in many studies. This contradicts the purpose of the standardization. The objectives of this study were to identify the major sources of this problem, and to help define or identify better coordinate systems for the standardization. This study systematically reviewed the principles and definition methods, and evaluated typical hand coordinate systems. This study confirms that, as accelerometers remain the major technology for vibration measurement, it is reasonable to standardize two types of coordinate systems: a tool-based basicentric (BC) system and an anatomically based biodynamic (BD) system. However, these coordinate systems are not well defined in the current standard. Definition of the standard BC system is confusing, and it can be interpreted differently; as a result, it has been inconsistently applied in various standards and studies. The standard hand BD system is defined using the orientation of the third metacarpal bone. It is neither convenient nor defined based on important biological or biodynamic features. This explains why it is rarely used in practice. To resolve these inconsistencies and deficiencies, we proposed a revised method for defining the realistic handle BC system and an alternative method for defining the hand BD system. A fingertip-based BD system for measuring the principal grip force is also proposed based on an important feature of the grip force confirmed in this study. PMID:26929824

  13. Three-dimensional acetabular orientation measurement in a reliable coordinate system among one hundred Chinese

    PubMed Central

    Zhang, Henghui; Wang, Yiping; Ai, Songtao; Chen, Xiaojun; Wang, Liao; Dai, Kerong

    2017-01-01

    Determining three-dimensional (3D) acetabular orientation is important for several orthopaedic scenarios, but the complex geometries of both pelvis and acetabulum make measurements of orientation unreliable. Acetabular orientation may also differ between the sexes or racial groups. We aimed to (1) establish and evaluate a novel method for measuring 3D acetabular orientation, (2) apply this new method to a large population of Chinese subjects, and (3) report relevant characteristics of native acetabular orientation in this population. We obtained computed tomography scans taken for non-orthopaedic indications in 100 Chinese subjects (50 male, 50 female). A novel algorithm tailored to segmentation of the hip joint was used to construct 3D pelvic models from these scans. We developed a surface-based method to establish a reliable 3D pelvic coordinate system and software to semi-automatically measure 3D acetabular orientation. Differences in various acetabular orientations were compared within and between subjects, between male and female subjects, and between our subjects and subjects previously reported by another group. The reported method was reliable (intraclass correlation coefficient >0.999). Acetabular orientations were symmetrical within subjects, but ranged widely between subjects. The sexes differed significantly in acetabular anteversion (average difference, 3.0°; p < 0.001) and inclination (1.5°; p < 0.03). Acetabular anteversion and inclination were substantially smaller among our Chinese subjects than previously reported for American subjects. Thus, our method was reliable and sensitive, and we detected sex differences in 3D acetabular orientation. Awareness of differences between the sexes and races is the first step towards better reconstruction of the hip joint for all individuals and could also be applied to other orthopaedic scenarios. PMID:28207829

  14. Dimensional characterization of a quasispherical resonator by microwave and coordinate measurement techniques

    NASA Astrophysics Data System (ADS)

    Underwood, R.; Flack, D.; Morantz, P.; Sutton, G.; Shore, P.; de Podesta, M.

    2011-02-01

    We describe the dimensional characterization of copper quasisphere NPL-Cranfield 2. The quasisphere is assembled from two hemispheres such that the internal shape is a triaxial ellipsoid, the major axes of which have nominal radii 62.000 mm, 62.031 mm and 62.062 mm. The artefact has been manufactured using diamond-turning technology and shows a deviation from design form of less than ±1 µm over most of its surface. Our characterization involves both coordinate measuring machine (CMM) experiments and microwave resonance spectroscopy. We have sought to reduce the dimensional uncertainty below the maximum permissible error of the CMM by comparative measurements with silicon and Zerodur spheres of known volume. Using this technique we determined the equivalent radius with an uncertainty of u(k = 1) = 114 nm, a fractional uncertainty of 1.8 parts in 106. Due to anisotropy of the probe response, we could only determine the eccentricities of the quasihemispheres with a fractional uncertainty of approximately 2%. Our microwave characterization uses the TM11 to TM18 resonances. We find the equivalent radius inferred from analysis of these modes to be consistent within ±4 nm with an overall uncertainty u(k = 1) = 11 nm. We discuss corrections for surface conductivity, waveguide perturbations and dielectric surface layers. We find that the CMM radius estimates derived from each hemisphere cannot be used to accurately predict the equivalent radius of the assembled resonator for two reasons. Firstly, the equatorial flanges are flat only to within ±1 µm, leading to an equatorial 'gap' whose dimension cannot be reliably estimated. Secondly, the resonator undergoes significant elastic distortion when the bolts connecting the hemispheres are tightened. We provide CMM and microwave measurements to support these conclusions in addition to finite-element modelling. Finally, we consider the implications of this work on a forthcoming experiment to determine the Boltzmann constant

  15. Determination of the auroral O/1S/ production sources from coordinated rocket and satellite measurements

    NASA Technical Reports Server (NTRS)

    Sharp, W. E.; Torr, D. G.

    1979-01-01

    This paper examines the auroral excitation mechanisms using data collected in a satellite/rocket/aurora coordination. Past theories considered that variation with altitude of the emission from the O(1S) state is the same as that from the N2(+) first negative band system. Actually, the source function for O(1S) does not covary with N2(+) but has a smaller scale height. The covariation is due to quenching of the source function by O(3P). The steadiness of the aurora in a flight of the Michigan Airglow Payload allows the profile to be differentiated for direct comparison with theory. It is concluded that when most of the relevant variables for production of the O(1S) state are simultaneously measured in aurora, the major source functions are dissociative recombination of O2(+) above 210 km to apogee at 250 km, and below 180 km the energy transfer from N2(A3sigma) in the oxygen atom quenching reaction.

  16. Analyzing Group Coordination when Solving Geometry Problems with Dynamic Geometry Software

    ERIC Educational Resources Information Center

    Oner, Diler

    2013-01-01

    In CSCL research, collaborative activity is conceptualized along various yet intertwined dimensions. When functioning within these multiple dimensions, participants make use of several resources, which can be social or content-related (and sometimes temporal) in nature. It is the effective coordination of these resources that appears to…

  17. Hydrothermal alteration and diagenesis of terrestrial lacustrine pillow basalts: Coordination of hyperspectral imaging with laboratory measurements

    NASA Astrophysics Data System (ADS)

    Greenberger, Rebecca N.; Mustard, John F.; Cloutis, Edward A.; Mann, Paul; Wilson, Janette H.; Flemming, Roberta L.; Robertson, Kevin M.; Salvatore, Mark R.; Edwards, Christopher S.

    2015-12-01

    We investigate an outcrop of ∼187 Ma lacustrine pillow basalts of the Talcott Formation exposed in Meriden, Connecticut, USA, focusing on coordinated analyses of one pillow lava to characterize the aqueous history of these basalts in the Hartford Basin. This work uses a suite of multidisciplinary measurements, including hyperspectral imaging, other spectroscopic techniques, and chemical and mineralogical analyses, from the microscopic scale up to the scale of an outcrop. The phases identified in the sample are albite, large iron oxides, and titanite throughout; calcite in vesicles; calcic clinopyroxene, aegirine, and Fe/Mg-bearing clay in the rind; and fine-grained hematite and pyroxenes in the interior. Using imaging spectroscopy, the chemistry and mineralogy results extend to the hand sample and larger outcrop. From all of the analyses, we suggest that the pillow basalts were altered initially after emplacement, either by heated lake water or magmatic fluids, at temperatures of at least 400-600 °C, and the calcic clinopyroxenes and aegirine identified in the rind are a preserved record of that alteration. As the hydrothermal system cooled to slightly lower temperatures, clays formed in the rind, and, during this alteration, the sample oxidized to form hematite in the matrix of the interior and Fe3+ in the pyroxenes in the rind. During the waning stages of the hydrothermal system, calcite precipitated in vesicles within the rind. Later, diagenetic processes albitized the sample, with albite replacing plagioclase, lining vesicles, and accreting onto the exterior of the sample. This albitization or Na-metasomatism occurred when the lake within the Hartford Basin evaporated during a drier past climatic era, resulting in Na-rich brines. As Ca-rich plagioclase altered to albite, Ca was released into solution, eventually precipitating as calcite in previously-unfilled vesicles, dominantly in the interior of the pillow. Coordinated analyses of this sample permit

  18. Empirical force field for cisplatin based on quantum dynamics data: case study of new parameterization scheme for coordination compounds.

    PubMed

    Yesylevskyy, S; Cardey, Bruno; Kraszewski, S; Foley, Sarah; Enescu, Mironel; da Silva, Antônio M; Dos Santos, Hélio F; Ramseyer, Christophe

    2015-10-01

    Parameterization of molecular complexes containing a metallic compound, such as cisplatin, is challenging due to the unconventional coordination nature of the bonds which involve platinum atoms. In this work, we develop a new methodology of parameterization for such compounds based on quantum dynamics (QD) calculations. We show that the coordination bonds and angles are more flexible than in normal covalent compounds. The influence of explicit solvent is also shown to be crucial to determine the flexibility of cisplatin in quantum dynamics simulations. Two empirical topologies of cisplatin were produced by fitting its atomic fluctuations against QD in vacuum and QD with explicit first solvation shell of water molecules respectively. A third topology built in a standard way from the static optimized structure was used for comparison. The later one leads to an excessively rigid molecule and exhibits much smaller fluctuations of the bonds and angles than QD reveals. It is shown that accounting for the high flexibility of cisplatin molecule is needed for adequate description of its first hydration shell. MD simulations with flexible QD-based topology also reveal a significant decrease of the barrier of passive diffusion of cisplatin accross the model lipid bilayer. These results confirm that flexibility of organometallic compounds is an important feature to be considered in classical molecular dynamics topologies. Proposed methodology based on QD simulations provides a systematic way of building such topologies.

  19. Beyond the Niche: Tissue-Level Coordination of Stem Cell Dynamics

    PubMed Central

    O’Brien, Lucy Erin; Bilder, David

    2014-01-01

    Adult animals rely on populations of stem cells to ensure organ function throughout their lifetime. Stem cells are governed by signals from stem cell niches, and much is known about how single niches promote stemness and direct stem cell behavior. However, most organs contain a multitude of stem cell–niche units, which are often distributed across the entire expanse of the tissue. Beyond the biology of individual stem cell–niche interactions, the next challenge is to uncover the tissue-level processes that orchestrate spatial control of stem-based renewal, repair, and remodeling throughout a whole organ. Here we examine what is known about higher order mechanisms for interniche coordination in epithelial organs, whose simple geometry offers a promising entry point for understanding the regulation of niche number, distribution, and activity. We also consider the potential existence of stem cell territories and how tissue architecture may influence niche coordination. PMID:23937350

  20. Beyond the niche: tissue-level coordination of stem cell dynamics.

    PubMed

    O'Brien, Lucy Erin; Bilder, David

    2013-01-01

    Adult animals rely on populations of stem cells to ensure organ function throughout their lifetime. Stem cells are governed by signals from stem cell niches, and much is known about how single niches promote stemness and direct stem cell behavior. However, most organs contain a multitude of stem cell-niche units, which are often distributed across the entire expanse of the tissue. Beyond the biology of individual stem cell-niche interactions, the next challenge is to uncover the tissue-level processes that orchestrate spatial control of stem-based renewal, repair, and remodeling throughout a whole organ. Here we examine what is known about higher order mechanisms for interniche coordination in epithelial organs, whose simple geometry offers a promising entry point for understanding the regulation of niche number, distribution, and activity. We also consider the potential existence of stem cell territories and how tissue architecture may influence niche coordination.

  1. Emergence of Coordinated Neural Dynamics Underlies Neuroprosthetic Learning and Skillful Control.

    PubMed

    Athalye, Vivek R; Ganguly, Karunesh; Costa, Rui M; Carmena, Jose M

    2017-02-22

    During motor learning, movements and underlying neural activity initially exhibit large trial-to-trial variability that decreases over learning. However, it is unclear how task-relevant neural populations coordinate to explore and consolidate activity patterns. Exploration and consolidation could happen for each neuron independently, across the population jointly, or both. We disambiguated among these possibilities by investigating how subjects learned de novo to control a brain-machine interface using neurons from motor cortex. We decomposed population activity into the sum of private and shared signals, which produce uncorrelated and correlated neural variance, respectively, and examined how these signals' evolution causally shapes behavior. We found that initially large trial-to-trial movement and private neural variability reduce over learning. Concomitantly, task-relevant shared variance increases, consolidating a manifold containing consistent neural trajectories that generate refined control. These results suggest that motor cortex acquires skillful control by leveraging both independent and coordinated variance to explore and consolidate neural patterns.

  2. Rotor/bearing system dynamic stiffness measurements

    NASA Technical Reports Server (NTRS)

    Muszynska, A.

    1985-01-01

    Sweep perturbation testing as used in Modal Analysis when applied to a rotating machine has to take into consideration the machine dynamic state of equilibrium at its operational rotative speed. This stands in contrasts to a static equilibrium of nonrotating structures. The rotational energy has a significant influence on rotor dynamic characteristics. The best perturbing input for rotating machines is a forward or reverse rotating, circular force applied directly to the shaft. Determination of Dynamic Stiffness Characteristics of the rotor bearing system by nonsynchronous perturbation of a symmetric rotating shaft supported in one relatively rigid and one oil lubricated bearing.

  3. Direct field measurement of the dynamic amplification in a bridge

    NASA Astrophysics Data System (ADS)

    Carey, Ciarán; OBrien, Eugene J.; Malekjafarian, Abdollah; Lydon, Myra; Taylor, Su

    2017-02-01

    In this paper, the level of dynamics, as described by the Assessment Dynamic Ratio (ADR), is measured directly through a field test on a bridge in the United Kingdom. The bridge was instrumented using fiber optic strain sensors and piezo-polymer weigh-in-motion sensors were installed in the pavement on the approach road. Field measurements of static and static-plus-dynamic strains were taken over 45 days. The results show that, while dynamic amplification is large for many loading events, these tend not to be the critical events. ADR, the allowance that should be made for dynamics in an assessment of safety, is small.

  4. CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation

    PubMed Central

    Tan, Minghui; Cha, Caihui; Ye, Yongheng; Zhang, Jifeng; Li, Sumei; Wu, Fengming; Gong, Sitang; Guo, Guoqing

    2015-01-01

    Cytoskeleton dynamics are critical phenomena that underpin many fundamental cellular processes. Collapsin response mediator proteins (CRMPs) are highly expressed in the developing nervous system, mediating growth cone guidance, neuronal polarity, and axonal elongation. However, whether and how CRMPs associate with microtubules and actin coordinated cytoskeletal dynamics remain unknown. In this study, we demonstrated that CRMP2 and CRMP4 interacted with tubulin and actin in vitro and colocalized with the cytoskeleton in the transition-zone in developing growth cones. CRMP2 and CRMP4 also interacted with one another coordinately to promote growth cone development and axonal elongation. Genetic silencing of CRMP2 enhanced, whereas overexpression of CRMP2 suppressed, the inhibitory effects of CRMP4 knockdown on axonal development. In addition, knockdown of CRMP2 or overexpression of truncated CRMP2 reversed the promoting effect of CRMP4. With the overexpression of truncated CRMP2 or CRMP4 lacking the cytoskeleton interaction domain, the promoting effect of CRMP was suppressed. These data suggest a model in which CRMP2 and CRMP4 form complexes to bridge microtubules and actin and thus work cooperatively to regulate growth cone development and axonal elongation. PMID:26064693

  5. Human tissue color as viewed in high dynamic range optical spectral transmission measurements.

    PubMed

    Petrov, Georgi I; Doronin, Alexander; Whelan, Harry T; Meglinski, Igor; Yakovlev, Vladislav V

    2012-09-01

    High dynamic range optical-to-near-infrared transmission measurements for different parts of human body in the spectral range from 650 to 950 nm have been performed. Experimentally measured spectra are correlated with Monte Carlo simulations using chromaticity coordinates in CIE 1976 L*a*b* color space. Both a qualitative and a quantitative agreement have been found, paving a new way of characterizing human tissues in vivo. The newly developed experimental and computational platform for assessing tissue transmission spectra is anticipated to have a considerable impact on identifying favorable conditions for laser surgery and optical diagnostics, while providing supplementary information about tissue properties.

  6. High speed high dynamic range high accuracy measurement system

    SciTech Connect

    Deibele, Craig E.; Curry, Douglas E.; Dickson, Richard W.; Xie, Zaipeng

    2016-11-29

    A measuring system includes an input that emulates a bandpass filter with no signal reflections. A directional coupler connected to the input passes the filtered input to electrically isolated measuring circuits. Each of the measuring circuits includes an amplifier that amplifies the signal through logarithmic functions. The output of the measuring system is an accurate high dynamic range measurement.

  7. Dynamic Forces in Spur Gears - Measurement, Prediction, and Code Validation

    NASA Technical Reports Server (NTRS)

    Oswald, Fred B.; Townsend, Dennis P.; Rebbechi, Brian; Lin, Hsiang Hsi

    1996-01-01

    Measured and computed values for dynamic loads in spur gears were compared to validate a new version of the NASA gear dynamics code DANST-PC. Strain gage data from six gear sets with different tooth profiles were processed to determine the dynamic forces acting between the gear teeth. Results demonstrate that the analysis code successfully simulates the dynamic behavior of the gears. Differences between analysis and experiment were less than 10 percent under most conditions.

  8. Penta- and hexa-coordinate ferric hemoglobins display distinct pH titration profiles measured by Soret peak shifts.

    PubMed

    Uppal, Sheetal; Kumar, Amit; Shandilya, Manish; Mukhi, Nitika; Singh, Amit Kumar; Kateriya, Suneel; Kaur, Jagreet; Kundu, Suman

    2016-10-01

    Hemoglobins with diverse characteristics have been identified in all kingdoms of life. Their ubiquitous presence indicates that these proteins play important roles in physiology, though function for all hemoglobins are not yet established with certainty. Their physiological role may depend on their ability to bind ligands, which in turn is dictated by their heme chemistry. However, we have an incomplete understanding of the mechanism of ligand binding for these newly discovered hemoglobins and the measurement of their kinetic parameters depend on their coordination at the heme iron. To gain insights into their functional role, it is important to categorize the new hemoglobins into either penta- or hexa-coordinated varieties. We demonstrate that simple pH titration and absorbance measurements can determine the coordination state of heme iron atom in ferric hemoglobins, thus providing unambiguous information about the classification of new globins. This method is rapid, sensitive and requires low concentration of protein. Penta- and hexa-coordinate hemoglobins displayed distinct pH titration profiles as observed in a variety of hemoglobins. The pentacoordinate distal histidine mutant proteins of hexacoordinate hemoglobins and ligand-bound hexacoordinate forms of pentacoordinate hemoglobins reverse the pH titration profiles, thus validating the sensitivity of this spectroscopic technique.

  9. Measurement fidelity in the presence of coherent dynamics or dissipation

    NASA Astrophysics Data System (ADS)

    You, Jian-Qiang; Ashhab, S.; Nori, Franco

    2011-03-01

    We analyze the problem of a charge qubit probed by a quantum point contact when the measurement is concurrent with Hamiltonian-induced coherent dynamics or dissipation. This additional dynamics changes the state of the qubit before the measurement is completed. As a result, the measurement fidelity is reduced. We calculate the reduction in measurement fidelity in these cases. References: S. Ashhab, J. Q. You, and F. Nori, New J. Phys. 11, 083017 (2009); Phys. Scr. T137, 014005 (2009).

  10. Microfilament-coordinated adhesion dynamics drives single cell migration and shapes whole tissues

    PubMed Central

    Aguilar-Cuenca, Rocio; Llorente-Gonzalez, Clara; Vicente, Carlos; Vicente-Manzanares, Miguel

    2017-01-01

    Cell adhesion to the substratum and/or other cells is a crucial step of cell migration. While essential in the case of solitary migrating cells (for example, immune cells), it becomes particularly important in collective cell migration, in which cells maintain contact with their neighbors while moving directionally. Adhesive coordination is paramount in physiological contexts (for example, during organogenesis) but also in pathology (for example, tumor metastasis). In this review, we address the need for a coordinated regulation of cell-cell and cell-matrix adhesions during collective cell migration. We emphasize the role of the actin cytoskeleton as an intracellular integrator of cadherin- and integrin-based adhesions and the emerging role of mechanics in the maintenance, reinforcement, and turnover of adhesive contacts. Recent advances in understanding the mechanical regulation of several components of cadherin and integrin adhesions allow us to revisit the adhesive clutch hypothesis that controls the degree of adhesive engagement during protrusion. Finally, we provide a brief overview of the major impact of these discoveries when using more physiological three-dimensional models of single and collective cell migration. PMID:28299195

  11. Numbers and Measuring, Learning With TOR: MINNEMAST Coordinated Mathematics - Science Series, Unit 16.

    ERIC Educational Resources Information Center

    Vogt, Elaine E., Ed.

    This volume is the sixteenth in a series of 29 coordinated MINNEMAST units in mathematics and science for kindergarten and the primary grades. Intended for use by second-grade teachers, this unit guide provides a summary and overview of the unit, a list of materials needed, and descriptions of five groups of lessons. The purposes and procedures…

  12. Body measurements of Chinese males in dynamic postures and application.

    PubMed

    Wang, Y J; Mok, P Y; Li, Y; Kwok, Y L

    2011-11-01

    It is generally accepted that there is a relationship between body dimensions, body movement and clothing wearing ease design, and yet previous research in this area has been neither sufficient nor systematic. This paper proposes a method to measure the human body in the static state and in 17 dynamic postures, so as to understand dimensional changes of different body parts during dynamic movements. Experimental work is carried out to collect 30 measurements of 10 male Chinese subjects in both static and dynamic states. Factor analysis is used to analyse body measurement data in a static state, and such key measurements describe the characteristics of different body figures. Moreover, one-way ANOVA is used to analyse how dynamic postures affect these key body measurements. Finally, an application of the research results is suggested: a dynamic block patternmaking method for high-performance clothing design.

  13. Novel coordinates for nonlinear multibody motion with applications to spacecraft dynamics and control

    NASA Astrophysics Data System (ADS)

    Schaub, Hanspeter

    1998-12-01

    Novel sets of attitude coordinates called the Stereographic Parameters (SPs) and configuration quasivelocity coordinates called the Eigenfactor Quasivelocities (EQVs) are discussed. The SPs are generated through stereographic projections of the Euler parameter constraint hypersphere onto hyperplanes. SP sets are non-unique and have distinct alternate sets referred to as shadow sets. They abide by the same differential kinematic equation, but generally display a different singular behavior. Explicit expressions are developed that map the original SP set to the shadow set and thus avoid any singularities. Both symmetric SPs such as the classical and Modified Rodrigues Parameters (MRPs), as well as asymmetric SPs are discussed. A globally asymptotically stable MRP feedback law which tracks any reference trajectory is presented. Both unsaturated and saturated control cases are discussed. Further, an MRP costate switching condition is developed that allows both original and shadow MRPs to be used simultaneously in optimal control problems. The Lagrange equations of motion in terms of the n-dimensional EQV vector are developed. The EQV formulation has an identity mass matrix which results in no matrix inverse being taken in numerical simulations. An explicit expression is presented that incorporates Pfaffian non-holonomic constraints into the EQV formulation without increasing the system order. Unfortunately, the use of EQV in numerical simulations only proved beneficial in selected cases. Generally the computational burden proved too high. However, the EQVs are found to be valuable when used as velocity feedback coordinates. EQV feedback laws have an exponentially decaying kinetic energy, superior performance to traditional state velocity feedback laws and are found to decouple the motion of multi-link robotic systems. The equations of motion and steering laws of spacecraft containing Variable Speed Control Moment Gyroscopes (VSCMGs) are developed. Contrary to classical

  14. Further development of the dynamic gas temperature measurement system

    NASA Technical Reports Server (NTRS)

    Elmore, D. L.; Robinson, W. W.; Watkins, W. B.

    1986-01-01

    A compensated thermocouple measurement method was experimentally verified. Dynamic signal content from an atmospheric pressure laboratory burner was measured by the dynamic temperature sensor and a relatively delicate fine-wire resistance thermometer. Compensated data from the two dynamic temperature sensor thermoelements were compared with the compensated fine-wire data in the frequency domain. Absolute differences between spectral line amplitudes measured with different sensors are small relative to the mean temperature and verify the compenation method. Increases in precision of the measurement method require optimization of several factors, and directions for further work are identified.

  15. Sliding mode coordination control for multiagent systems with underactuated agent dynamics

    NASA Astrophysics Data System (ADS)

    Ghasemi, Masood; Nersesov, Sergey G.; Clayton, Garrett; Ashrafiuon, Hashem

    2014-12-01

    In this paper, we develop a new integrated coordinated control and obstacle avoidance approach for a general class of underactuated agents. We use graph-theoretic notions to characterise communication topology in the network of underactuated agents as determined by the information flow directions and captured by the graph Laplacian matrix. Obstacle avoidance is achieved by surrounding the stationary as well as moving obstacles by elliptical or other convex shapes that serve as stable periodic solutions to planar systems of ordinary differential equations and using transient trajectories of those systems to navigate the agents around the obstacles. Decentralised controllers for individual agents are designed using sliding mode control approach and are only based on data communicated from the neighbouring agents. We demonstrate the efficacy of our theoretical approach using an example of a system of wheeled mobile robots that reach and maintain a desired formation. Finally, we validate our results experimentally.

  16. Stable reduced-order models of generalized dynamical systems using coordinate-transformed Arnoldi algorithms

    SciTech Connect

    Silveira, L.M.; Kamon, M.; Elfadel, I.; White, J.

    1996-12-31

    Model order reduction based on Krylov subspace iterative methods has recently emerged as a major tool for compressing the number of states in linear models used for simulating very large physical systems (VLSI circuits, electromagnetic interactions). There are currently two main methods for accomplishing such a compression: one is based on the nonsymmetric look-ahead Lanczos algorithm that gives a numerically stable procedure for finding Pade approximations, while the other is based on a less well characterized Arnoldi algorithm. In this paper, we show that for certain classes of generalized state-space systems, the reduced-order models produced by a coordinate-transformed Arnoldi algorithm inherit the stability of the original system. Complete Proofs of our results will be given in the final paper.

  17. Coordinated Observations of X-ray and High-resolution EUV Active Region Dynamics

    NASA Technical Reports Server (NTRS)

    Savage, Sabrina

    2013-01-01

    The recently-launched High-resolution Coronal imager (Hi-C) sounding rocket provided the highest resolution images of coronal loops and other small-scale structures in the 193 Angstrom passband to date. With just 5 minutes of observations, the instrument recorded a variety of dynamic coronal events -- including even a small B-class flare. We will present our results comparing these extreme-ultraviolet (EUV) observations with X-ray imaging from Hinode/XRT as well as EUV AIA data to identify sources of hot plasma rooted in the photosphere and track their affect on the overall topology and dynamics of the active region.

  18. Coordinated Observations of X-ray and High-Resolution EUV Active Region Dynamics

    NASA Technical Reports Server (NTRS)

    Savage, Sabrina; Cirtain, Jonathan; Winebarger, Amy; Kobayashi, Ken; Golub, Leon; Korreck, Kelly

    2013-01-01

    The recently-launched High-resolution Coronal imager (Hi-C) sounding rocket provided the highest resolution images of coronal loops and other small-scale structures in the 193 Angstrom passband to date. With just 5 minutes of observations, the instrument recorded a variety of dynamic coronal events -- including even a small B-class flare. We will present our results comparing these extreme-ultraviolet (EUV) observations with X-ray imaging from Hinode/XRT as well as EUV AIA data to identify sources of hot plasma rooted in the photosphere and track their affect on the overall topology and dynamics of the active region.

  19. System for measuring the coordinates of tire surfaces in transient conditions when rolling over obstacles: description of the system and performance analysis.

    PubMed

    Castellini, Paolo; Di Giuseppe, Andrea

    2008-06-01

    This paper describes the development of a system for measuring surface coordinates (commonly known as "shape measurements") which is able to give the temporal evolution of the position of the tire sidewall in transient conditions (such as during braking, when there are potholes or when the road surface is uneven) which may or may not be reproducible. The system is based on the well-known technique of projecting and observing structured light using a digital camera with an optical axis which is slanted with respect to the axis of the projector. The transient nature of the phenomenon has led to the development of specific innovative solutions as regards image processing algorithms. This paper briefly describes the components which make up the measuring system and presents the results of the measurements carried out on the drum bench. It then analyses the performance of the measuring system and the sources of uncertainty which led to the development of the system for a specific dynamic application: impact with an obstacle (cleat test). The measuring system guaranteed a measurement uncertainty of 0.28 mm along the Z axis (the axial direction of the tire) with a measurement range of 250(X) x 80(Y) x 25(Z) mm(3), with the tire rolling at a speed of up to 30 km/h.

  20. System for measuring the coordinates of tire surfaces in transient conditions when rolling over obstacles: Description of the system and performance analysis

    SciTech Connect

    Castellini, Paolo; Di Giuseppe, Andrea

    2008-06-15

    This paper describes the development of a system for measuring surface coordinates (commonly known as ''shape measurements'') which is able to give the temporal evolution of the position of the tire sidewall in transient conditions (such as during braking, when there are potholes or when the road surface is uneven) which may or may not be reproducible. The system is based on the well-known technique of projecting and observing structured light using a digital camera with an optical axis which is slanted with respect to the axis of the projector. The transient nature of the phenomenon has led to the development of specific innovative solutions as regards image processing algorithms. This paper briefly describes the components which make up the measuring system and presents the results of the measurements carried out on the drum bench. It then analyses the performance of the measuring system and the sources of uncertainty which led to the development of the system for a specific dynamic application: impact with an obstacle (cleat test). The measuring system guaranteed a measurement uncertainty of 0.28 mm along the Z axis (the axial direction of the tire) with a measurement range of 250(X)x80(Y)x25(Z) mm{sup 3}, with the tire rolling at a speed of up to 30 km/h.

  1. Modelling and calibration technique of laser triangulation sensors for integration in robot arms and articulated arm coordinate measuring machines.

    PubMed

    Santolaria, Jorge; Guillomía, David; Cajal, Carlos; Albajez, José A; Aguilar, Juan J

    2009-01-01

    A technique for intrinsic and extrinsic calibration of a laser triangulation sensor (LTS) integrated in an articulated arm coordinate measuring machine (AACMM) is presented in this paper. After applying a novel approach to the AACMM kinematic parameter identification problem, by means of a single calibration gauge object, a one-step calibration method to obtain both intrinsic-laser plane, CCD sensor and camera geometry-and extrinsic parameters related to the AACMM main frame has been developed. This allows the integration of LTS and AACMM mathematical models without the need of additional optimization methods after the prior sensor calibration, usually done in a coordinate measuring machine (CMM) before the assembly of the sensor in the arm. The experimental tests results for accuracy and repeatability show the suitable performance of this technique, resulting in a reliable, quick and friendly calibration method for the AACMM final user. The presented method is also valid for sensor integration in robot arms and CMMs.

  2. Coordinated power control of unified power flow controller and its application for enhancing dynamic power system performance

    NASA Astrophysics Data System (ADS)

    Fang, Wanliang

    This thesis focuses on reporting my research study on a problem area relating to use of Unified Power Flow Controller (UPFC) for coordinating load flow in power systems so as to enhance their static and dynamic performance by having more secure and economical operation and higher dynamic stability margin. UPFC is considered as one of the most promising devices for implementing the Flexible AC Transmission System (FACTS) concept. Although development of UPFC is still on an infant stage, probing into its impact on power system operation is actively pursued and significant effort has been devoted to put it forward as a practical FACTS device and as a challenging academic research object. In order to consider UPFC as a basic power system element, it has to be involved in associated load flow computation essentially for power system control analysis and operational planning. An up front problem for design engineers is therefore pointing to a need to modify existing load flow program so as to accommodate interactions of UPFCs. A lot of research output start coming out but their computational efficiency are not high enough. In this regard, I propose two methods to perform the UPFC embedded load flow calculation to cater for two different types of application. The first one caters for analyzing direct control of load flow on transmission lines with embedded UPFCs. In this type of problem, active and reactive power of the lines, as well as the magnitude of bus voltages are priori given. The load flow solution can then be obtained and enables the UPFC parameters to be determined with a significantly improved computational efficiency. The second one works in contrary to the first one by which parameters of UPFCs are given before hand and the load flow calculation is performed for conforming a feasible operation. It can be regarded as an indirect load flow control calculation which is useful in planning stage for incorporating UPFC into existing system and/or carrying out

  3. New near-wall models with dynamic subgrid scale closure for large eddy simulation in curvilinear coordinates for complex geometries

    NASA Astrophysics Data System (ADS)

    Barsamian, Hagop Raffi

    2000-10-01

    This dissertation presents modifications and improvements to the dynamic subgrid scale model and introduces a new wall model. These are applied to the large eddy simulation technique in curvilinear coordinates. They are then validated and tested in three-dimensional complex geometries. The large eddy simulation method captures many scales of turbulence up to the grid size. A closure model is used to simulate subgrid turbulence. The Smagorinsky and dynamic subgrid models are presented and tested. The dynamic model overcomes many of the deficiencies of the Smagorinsky subgrid scale model. Spatial and temporal low-pass filters have been introduced in the dynamic subgrid scale model for numerical stability. No practical differences have been observed between the Smagorinsky and dynamic models. Several near-wall models are considered for the large eddy simulation technique. A local averaging technique makes these models applicable to complex geometries. A new model is introduced which overcomes planar averaging near the wall and captures ejection and sweep effects. Special treatment of inlet boundary conditions was introduced. These models have been implemented in a large eddy simulation computer program that uses a strongly conservative curvilinear coordinate formulation. The covariant projections are used as the dependent variables in a staggered methodology. The body fitted grids are advantageous in complex geometry descriptions. Results are validated in a lid driven cavity flow at Reynolds number of 10000. A single tube in a channel is simulated to show the applicability of the models to complex geometries with attachment and separation as well as end-wall effects. The shedding effect was captured and turbulence characteristics were acceptable. One million nodes were used in a large eddy simulation of a three-dimensional tube bundle at Reynolds number of 21700. Results are presented in the form of visualization and compared with available experimental data. The

  4. GUI for Coordinate Measurement of an Image for the Estimation of Geometric Distortion of an Opto-electronic Display System

    NASA Astrophysics Data System (ADS)

    Saini, Surender Singh; Sardana, Harish Kumar; Pattnaik, Shyam Sundar

    2016-07-01

    Conventional image editing software in combination with other techniques are not only difficult to apply to an image but also permits a user to perform some basic functions one at a time. However, image processing algorithms and photogrammetric systems are developed in the recent past for real-time pattern recognition applications. A graphical user interface (GUI) is developed which can perform multiple functions simultaneously for the analysis and estimation of geometric distortion in an image with reference to the corresponding distorted image. The GUI measure, record, and visualize the performance metric of X/Y coordinates of one image over the other. The various keys and icons provided in the utility extracts the coordinates of distortion free reference image and the image with geometric distortion. The error between these two corresponding points gives the measure of distortion and also used to evaluate the correction parameters for image distortion. As the GUI interface minimizes human interference in the process of geometric correction, its execution just requires use of icons and keys provided in the utility; this technique gives swift and accurate results as compared to other conventional methods for the measurement of the X/Y coordinates of an image.

  5. Leading-process actomyosin coordinates organelle positioning and adhesion receptor dynamics in radially migrating cerebellar granule neurons

    DOE PAGES

    Trivedi, Niraj; Ramahi, Joseph S.; Karakaya, Mahmut; ...

    2014-12-02

    During brain development, neurons migrate from germinal zones to their final positions to assemble neural circuits. A unique saltatory cadence involving cyclical organelle movement (e.g., centrosome motility) and leading-process actomyosin enrichment prior to nucleokinesis organizes neuronal migration. While functional evidence suggests that leading-process actomyosin is essential for centrosome motility, the role of the actin-enriched leading process in globally organizing organelle transport or traction forces remains unexplored. Our results show that myosin ii motors and F-actin dynamics are required for Golgi apparatus positioning before nucleokinesis in cerebellar granule neurons (CGNs) migrating along glial fibers. Moreover, we show that primary cilia aremore » motile organelles, localized to the leading-process F-actin-rich domain and immobilized by pharmacological inhibition of myosin ii and F-actin dynamics. Finally, leading process adhesion dynamics are dependent on myosin ii and F-actin. In conclusion, we propose that actomyosin coordinates the overall polarity of migrating CGNs by controlling asymmetric organelle positioning and cell-cell contacts as these cells move along their glial guides.« less

  6. Leading-process actomyosin coordinates organelle positioning and adhesion receptor dynamics in radially migrating cerebellar granule neurons

    SciTech Connect

    Trivedi, Niraj; Ramahi, Joseph S.; Karakaya, Mahmut; Howell, Danielle; Kerekes, Ryan A.; Solecki, David J.

    2014-12-02

    During brain development, neurons migrate from germinal zones to their final positions to assemble neural circuits. A unique saltatory cadence involving cyclical organelle movement (e.g., centrosome motility) and leading-process actomyosin enrichment prior to nucleokinesis organizes neuronal migration. While functional evidence suggests that leading-process actomyosin is essential for centrosome motility, the role of the actin-enriched leading process in globally organizing organelle transport or traction forces remains unexplored. Our results show that myosin ii motors and F-actin dynamics are required for Golgi apparatus positioning before nucleokinesis in cerebellar granule neurons (CGNs) migrating along glial fibers. Moreover, we show that primary cilia are motile organelles, localized to the leading-process F-actin-rich domain and immobilized by pharmacological inhibition of myosin ii and F-actin dynamics. Finally, leading process adhesion dynamics are dependent on myosin ii and F-actin. In conclusion, we propose that actomyosin coordinates the overall polarity of migrating CGNs by controlling asymmetric organelle positioning and cell-cell contacts as these cells move along their glial guides.

  7. Metals on the move: zinc ions in cellular regulation and in the coordination dynamics of zinc proteins.

    PubMed

    Maret, Wolfgang

    2011-06-01

    Homeostatic control maintains essential transition metal ions at characteristic cellular concentrations to support their physiological functions and to avoid adverse effects. Zinc is especially widely used as a catalytic or structural cofactor in about 3000 human zinc proteins. In addition, the homeostatic control of zinc in eukaryotic cells permits functions of zinc(II) ions in regulation and in paracrine and intracrine signaling. Zinc ions are released from proteins through ligand-centered reactions in zinc/thiolate coordination environments, and from stores in cellular organelles, where zinc transporters participate in zinc loading and release. Muffling reactions allow zinc ions to serve as signaling ions (second messengers) in the cytosol that is buffered to picomolar zinc ion concentrations at steady-state. Muffling includes zinc ion binding to metallothioneins, cellular translocations of metallothioneins, delivery of zinc ions to transporter proteins, and zinc ion fluxes through cellular membranes with the result of removing the additional zinc ions from the cytosol and restoring the steady-state. Targets of regulatory zinc ions are proteins with sites for transient zinc binding, such as membrane receptors, enzymes, protein-protein interactions, and sensor proteins that control gene expression. The generation, transmission, targets, and termination of zinc ion signals involve proteins that use coordination dynamics in the inner and outer ligand spheres to control metal ion association and dissociation. These new findings establish critically important functions of zinc ions and zinc metalloproteins in cellular control.

  8. Microtubules as key coordinators of nuclear envelope and endoplasmic reticulum dynamics during mitosis.

    PubMed

    Schlaitz, Anne-Lore

    2014-07-01

    During mitosis, cells comprehensively restructure their interior to promote the faithful inheritance of DNA and cytoplasmic contents. In metazoans, this restructuring entails disassembly of the nuclear envelope, redistribution of its components into the endoplasmic reticulum (ER) and eventually nuclear envelope reassembly around the segregated chromosomes. The microtubule cytoskeleton has recently emerged as a critical regulator of mitotic nuclear envelope and ER dynamics. Microtubules and associated molecular motors tear open the nuclear envelope in prophase and remove nuclear envelope remnants from chromatin. Additionally, two distinct mechanisms of microtubule-based regulation of ER dynamics operate later in mitosis. First, association of the ER with microtubules is reduced, preventing invasion of ER into the spindle area, and second, organelle membrane is actively cleared from metaphase chromosomes. However, we are only beginning to understand the role of microtubules in shaping and distributing ER and other organelles during mitosis.

  9. Coordinate control of terminal dendrite patterning and dynamics by the membrane protein Raw.

    PubMed

    Lee, Jiae; Peng, Yun; Lin, Wen-Yang; Parrish, Jay Z

    2015-01-01

    The directional flow of information in neurons depends on compartmentalization: dendrites receive inputs whereas axons transmit them. Axons and dendrites likewise contain structurally and functionally distinct subcompartments. Axon/dendrite compartmentalization can be attributed to neuronal polarization, but the developmental origin of subcompartments in axons and dendrites is less well understood. To identify the developmental bases for compartment-specific patterning in dendrites, we screened for mutations that affect discrete dendritic domains in Drosophila sensory neurons. From this screen, we identified mutations that affected distinct aspects of terminal dendrite development with little or no effect on major dendrite patterning. Mutation of one gene, raw, affected multiple aspects of terminal dendrite patterning, suggesting that Raw might coordinate multiple signaling pathways to shape terminal dendrite growth. Consistent with this notion, Raw localizes to branch-points and promotes dendrite stabilization together with the Tricornered (Trc) kinase via effects on cell adhesion. Raw independently influences terminal dendrite elongation through a mechanism that involves modulation of the cytoskeleton, and this pathway is likely to involve the RNA-binding protein Argonaute 1 (AGO1), as raw and AGO1 genetically interact to promote terminal dendrite growth but not adhesion. Thus, Raw defines a potential point of convergence in distinct pathways shaping terminal dendrite patterning.

  10. Design and Mechanical Evaluation of a Capacitive Sensor-Based Indexed Platform for Verification of Portable Coordinate Measuring Instruments

    PubMed Central

    Avila, Agustín Brau; Mazo, Jorge Santolaria; Martín, Juan José Aguilar

    2014-01-01

    During the last years, the use of Portable Coordinate Measuring Machines (PCMMs) in industry has increased considerably, mostly due to their flexibility for accomplishing in-line measuring tasks as well as their reduced costs and operational advantages as compared to traditional coordinate measuring machines (CMMs). However, their operation has a significant drawback derived from the techniques applied in the verification and optimization procedures of their kinematic parameters. These techniques are based on the capture of data with the measuring instrument from a calibrated gauge object, fixed successively in various positions so that most of the instrument measuring volume is covered, which results in time-consuming, tedious and expensive verification procedures. In this work the mechanical design of an indexed metrology platform (IMP) is presented. The aim of the IMP is to increase the final accuracy and to radically simplify the calibration, identification and verification of geometrical parameter procedures of PCMMs. The IMP allows us to fix the calibrated gauge object and move the measuring instrument in such a way that it is possible to cover most of the instrument working volume, reducing the time and operator fatigue to carry out these types of procedures. PMID:24451458

  11. Measured Spacecraft Dynamic Effects on Atmospheric Science Instruments

    NASA Technical Reports Server (NTRS)

    Woodard, Stanley E.; Gell, David A.; Lay, Richard R.

    1997-01-01

    On September 1991, NASA launched the Upper Atmosphere Research Satellite. In addition to its atmospheric science mission, spacecraft dynamic effects on science measurements were analyzed. The investigation included two in-flight experiments to determine how each on-board instrument, subsystem and environmental disturbance contributed to the spacecraft dynamic response and how these disturbances affected science measurements. Three case studies are presented which show the impact of spacecraft dynamic response on science measurements. In the first case, correlation of independent atmospheric meridional wind measurements taken by two instruments with the spacecraft dynamic response demonstrated that excessive vibration (exceeding instrument pointing requirements) resulted in wind measurement disagreement. In the second case, solar array disturbances produced a spacecraft response signature on radiometer measurements. The signature explicitly demonstrated that if an instrument has sufficient spatial and temporal resolution, spacecraft dynamic response could impact measurements. In the final case, correlation of an instrument's fine sun sensor data and CO2 measurements demonstrated the effect of temporal and spatial sampling resolution and active pointing control on science measurements. The sun sensor had a frequency modulated characteristic due to spacecraft vibration and the periodic scanning of another instrument which was not present on the CO2 measurements.

  12. Measurement of dynamic bite force during mastication.

    PubMed

    Shimada, A; Yamabe, Y; Torisu, T; Baad-Hansen, L; Murata, H; Svensson, P

    2012-05-01

    Efficient mastication of different types and size of food depends on fast integration of sensory information from mechanoreceptors and central control mechanisms of jaw movements and applied bite force. The neural basis underlying mastication has been studied for decades but little progress in understanding the dynamics of bite force has been made mainly due to technical limitations of bite force recorders. The aims of this study were to develop a new intraoral bite force recorder which would allow the study of natural mastication without an increase in the occlusal vertical dimension and subsequently to analyze the relation between electromyographic (EMG) activity of jaw-closing muscles, jaw movements and bite force during mastication of five different types of food. Customized force recorders based on strain gauge sensors were fitted to the upper and lower molar teeth on the preferred chewing side in fourteen healthy and dentate subjects (21-39 years), and recordings were carried out during voluntary mastication of five different kinds of food. Intraoral force recordings were successively obtained from all subjects. anova showed that impulse of bite force as well as integrated EMG was significantly influenced by food (P<0·05), while time-related parameters were significantly affected by chewing cycles (P<0·001). This study demonstrates that intraoral force recordings are feasible and can provide new information on the dynamics of human mastication with direct implications for oral rehabilitation. We also propose that the control of bite force during mastication is achieved by anticipatory adjustment and encoding of bolus characteristics.

  13. Connection and coordination: the interplay between architecture and dynamics in evolved model pattern generators.

    PubMed

    Psujek, Sean; Ames, Jeffrey; Beer, Randall D

    2006-03-01

    We undertake a systematic study of the role of neural architecture in shaping the dynamics of evolved model pattern generators for a walking task. First, we consider the minimum number of connections necessary to achieve high performance on this task. Next, we identify architectural motifs associated with high fitness. We then examine how high-fitness architectures differ in their ability to evolve. Finally, we demonstrate the existence of distinct parameter subgroups in some architectures and show that these subgroups are characterized by differences in neuron excitabilities and connection signs.

  14. Further development of the dynamic gas temperature measurement system

    NASA Technical Reports Server (NTRS)

    Elmore, D. L.; Robinson, W. W.; Watkins, W. B.

    1985-01-01

    Two experiments for verifying the frequency response of a previously-developed dynamic gas temperature measurement system were performed. In both experiments, fine-wire resistance temperature sensors were used as standards. The compensated dynamic temperature sensor data will be compared with the standards to verify the compensation method. The experiments are described in detail.

  15. KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.

    PubMed

    Yeyati, Patricia L; Schiller, Rachel; Mali, Girish; Kasioulis, Ioannis; Kawamura, Akane; Adams, Ian R; Playfoot, Christopher; Gilbert, Nick; van Heyningen, Veronica; Wills, Jimi; von Kriegsheim, Alex; Finch, Andrew; Sakai, Juro; Schofield, Christopher J; Jackson, Ian J; Mill, Pleasantine

    2017-02-28

    Cilia assembly and disassembly are coupled to actin dynamics, ensuring a coherent cellular response during environmental change. How these processes are integrated remains undefined. The histone lysine demethylase KDM3A plays important roles in organismal homeostasis. Loss-of-function mouse models of Kdm3a phenocopy features associated with human ciliopathies, whereas human somatic mutations correlate with poor cancer prognosis. We demonstrate that absence of KDM3A facilitates ciliogenesis, but these resulting cilia have an abnormally wide range of axonemal lengths, delaying disassembly and accumulating intraflagellar transport (IFT) proteins. KDM3A plays a dual role by regulating actin gene expression and binding to the actin cytoskeleton, creating a responsive "actin gate" that involves ARP2/3 activity and IFT. Promoting actin filament formation rescues KDM3A mutant ciliary defects. Conversely, the simultaneous depolymerization of actin networks and IFT overexpression mimics the abnormal ciliary traits of KDM3A mutants. KDM3A is thus a negative regulator of ciliogenesis required for the controlled recruitment of IFT proteins into cilia through the modulation of actin dynamics.

  16. KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability

    PubMed Central

    Schiller, Rachel; Kawamura, Akane; Gilbert, Nick; Wills, Jimi; von Kriegsheim, Alex

    2017-01-01

    Cilia assembly and disassembly are coupled to actin dynamics, ensuring a coherent cellular response during environmental change. How these processes are integrated remains undefined. The histone lysine demethylase KDM3A plays important roles in organismal homeostasis. Loss-of-function mouse models of Kdm3a phenocopy features associated with human ciliopathies, whereas human somatic mutations correlate with poor cancer prognosis. We demonstrate that absence of KDM3A facilitates ciliogenesis, but these resulting cilia have an abnormally wide range of axonemal lengths, delaying disassembly and accumulating intraflagellar transport (IFT) proteins. KDM3A plays a dual role by regulating actin gene expression and binding to the actin cytoskeleton, creating a responsive “actin gate” that involves ARP2/3 activity and IFT. Promoting actin filament formation rescues KDM3A mutant ciliary defects. Conversely, the simultaneous depolymerization of actin networks and IFT overexpression mimics the abnormal ciliary traits of KDM3A mutants. KDM3A is thus a negative regulator of ciliogenesis required for the controlled recruitment of IFT proteins into cilia through the modulation of actin dynamics. PMID:28246120

  17. Conductance measurement circuit with wide dynamic range

    NASA Technical Reports Server (NTRS)

    Mount, Bruce E. (Inventor); Von Esch, Myron (Inventor)

    1994-01-01

    A conductance measurement circuit to measure conductance of a solution under test with an output voltage proportional to conductance over a 5-decade range, i.e., 0.01 uS to 1000 uS or from 0.1 uS to 10,000 uS. An increase in conductance indicates growth, or multiplication, of the bacteria in the test solution. Two circuits are used each for an alternate half-cycle time periods of an alternate squarewave in order to cause alternate and opposite currents to be applied to the test solution. The output of one of the two circuits may be scaled for a different range optimum switching frequency dependent upon the solution conductance and to enable uninterrupted measurement over the complete 5-decade range. This circuitry provides two overlapping ranges of conductance which can be read simultaneously without discontinuity thereby eliminating range switching within the basic circuitry. A VCO is used to automatically change the operating frequency according to the particular value of the conductance being measured, and comparators indicate which range is valid and also facilitate computer-controlled data acquisition. A multiplexer may be used to monitor any number of solutions under test continuously.

  18. Localized measurements of composite dynamic response for health monitoring

    NASA Astrophysics Data System (ADS)

    Webb, Sean; Oman, Kyle; Peters, Kara; Stan, Nikola; Chadderdon, Spencer; Selfridge, Richard; Schultz, Stephen

    2014-04-01

    We demonstrate the measurement of and applications for full-spectral measurements collected from FBG sensors in dynamic loading environments. The measurement of the dynamic response of a laminated plate to an impact event highlights the information gained during the event as compared to after the event. The measurement of damage induced spectral distortion in a thin plate during vibration loading demonstrates the capability of separating spectral distortion due to multiple effects, including damage and vibration loading. Finally, the measurement of the change in dynamic response of an adhesively bonded joint highlights the capability to measure the progression of fatigue damage. Confirmation that the change in FBG response is due to fatigue damage is performed through independent pulsed phase thermography imaging of the adhesively bonded joint.

  19. Incorporation of a tilting coordinate into the multidimensional Langevin dynamics of heavy-ion-induced fission: Analysis of experimental data from fusion-fission reactions

    NASA Astrophysics Data System (ADS)

    Nadtochy, P. N.; Ryabov, E. G.; Gegechkori, A. E.; Anischenko, Yu. A.; Adeev, G. D.

    2014-01-01

    A four-dimensional dynamical model was developed and applied to study fission characteristics in a wide range of a fissility parameter. Three collective shape coordinates and the K coordinate were considered dynamically from the ground-state deformation to the scission into fission fragments. A modified one-body mechanism for nuclear dissipation with a reduction coefficient ks of the contribution from a "wall" formula has been used in the study. The inclusion of the K coordinate in the dynamical consideration and use of the "chaos-weighted wall formula" with a deformation-dependent scaling factor ks(q1) lead to fairly good reproduction of the variances of the fission-fragment mass distribution and the prescission neutron multiplicity for a number of fissioning compound nuclei in a wide fissility range. The four-dimensional dynamical calculations describe better experimental prescission neutron multiplicity and variances of fission-fragment mass distribution for heaviest nuclei with respect to a three-dimensional dynamical model, where the K coordinate is assumed to be equal to zero. The estimate of a dissipation coefficient for the orientation degree of freedom, γK≃0.077 (MeVzs)-1/2, is good for heavy nuclei and a larger value of γK≃0.2 (MeVzs)-1/2 is needed for nuclei with mass ACN ≃ 200.

  20. HIGH DYNAMIC-RANGE HIGH SPEED LINAC CURRENT MEASUREMENTS

    SciTech Connect

    Deibele, Craig Edmond; Curry, Douglas E; Dickson, Richard W

    2012-01-01

    It is desired to measure the linac current of a charged particle beam with a consistent accuracy over a dynamic range of over 120 dB. Conventional current transformers suffer from droop, can be susceptible to electromagnetic interference (EMI), and can be bandwidth limited. A novel detector and electronics were designed to maximize dynamic range of about 120 dB and measure rise-times on the order of 10 nanoseconds.

  1. An efficient spectral method for computing dynamics of rotating two-component Bose-Einstein condensates via coordinate transformation

    NASA Astrophysics Data System (ADS)

    Ming, Ju; Tang, Qinglin; Zhang, Yanzhi

    2014-02-01

    In this paper, we propose an efficient and accurate numerical method for computing the dynamics of rotating two-component Bose-Einstein condensates (BECs) which is described by the coupled Gross-Pitaevskii equations (CGPEs) with an angular momentum rotation term and an external driving field. By introducing rotating Lagrangian coordinates, we eliminate the angular momentum rotation term from the CGPEs, which allows us to develop an efficient numerical method. Our method has spectral accuracy in all spatial dimensions and moreover it can be easily implemented in practice. To examine its performance, we compare our method with those reported in the literature. Numerical results show that to achieve the same accuracy, our method takes much shorter computing time. We also apply our method to study issues such as dynamics of vortex lattices and giant vortices in rotating two-component BECs. Furthermore, we generalize our method to solve the vector Gross-Pitaevskii equations (VGPEs) which is used to study rotating multi-component BECs.

  2. A comparative study of molecular dynamics in Cartesian and in internal coordinates: dynamical instability in the latter caused by nonlinearity of the equations of motion.

    PubMed

    Lee, Sang-Ho; Palmo, Kim; Krimm, Samuel

    2007-04-30

    The stability of a general molecular dynamics (MD) integration scheme is examined for simulations in generalized (internal plus external) coordinates (GCs). An analytic expression is derived for the local error in energy during each integration time step. This shows that the explicit dependence of the mass-matrix on GCs, which makes the system's Lagrange equations of motion nonlinear, causes MD simulations in GCs to be less stable than those in Cartesian coordinates (CCs). In terms of CCs, the corresponding mass-matrix depends only on atomic masses and thus atomistic motion is subject to the linear Newton equations, which makes the system more stable. Also investigated are two MD methods in GCs that utilize nonzero elements of the vibrational spectroscopic B-matrices. One updates positions and velocities in GCs that are iteratively adjusted so as to conform to the velocity Verlet equivalent in GCs. The other updates positions in GCs and velocities in CCs that are adjusted to satisfy the internal constraints of the new constrained WIGGLE MD scheme. The proposed methods are applied to an isolated n-octane molecule and their performances are compared with those of several CCMD schemes. The simulation results are found to be consistent with the analytic stability analysis. Finally, a method is presented for computing nonzero elements of B-matrices for external rotations without imposing the Casimir-Eckart conditions.

  3. Coordinated airborne, space borne, and ground based measurements of massive, thick haze layers during the SAFARI-2000 Dry Season Campaign

    NASA Astrophysics Data System (ADS)

    Schmid, B.; Russell, P.; Pilewskie, P.; Redemann, J.; Hobbs, P.; Holben, B.; Welton, E.; Campbell, J.; Hlavka, D.; McGill, M.; Chu, A.; Remer, L.; Torres, O.; Kahn, R.

    2001-12-01

    From August 13 to September 25, the Southern African Regional Science Initiative's (SAFARI 2000) dry-season airborne campaign coordinated ground-based measurement teams, multiple research aircraft, and satellite overpasses across nine African nations. Among many others, unique coordinated observations were made of the evolution of massive, thick haze layers produced by biomass burning, industrial emissions, marine and biogenic sources. The NASA Ames Airborne Tracking 14-channel Sunphotometer (AATS-14) was operated successfully aboard the University of Washington CV-580 during 24 data flights. The AATS-14 instrument measures the transmission of the direct solar beam at 14 discrete wavelengths (354-1558 nm) from which we derive spectral aerosol optical depths (AOD), columnar water vapor (CWV) and columnar ozone. Flying at different altitudes over a fixed location allows derivation of layer AOD and CWV. Data taken during feasible vertical profiles allows derivation of aerosol extinction and water vapor density. In the talk, we show comparisons with ground-based AERONET sun/sky photometer results, with ground based MPL-Net lidar data, and with measurements from a lidar (CPL) aboard the high-flying ER-2 aircraft. We will use measurements from the Ames Solar Spectral Flux Radiometer to derive estimates of solar spectral forcing as a function of aerosol thickness. Validations of MODIS, MISR and TOMS satellite aerosol and water vapor retrievals will also be presented.

  4. A measure of individual role in collective dynamics

    NASA Astrophysics Data System (ADS)

    Klemm, Konstantin; Serrano, M. Ángeles; Eguíluz, Víctor M.; Miguel, Maxi San

    2012-02-01

    Identifying key players in collective dynamics remains a challenge in several research fields, from the efficient dissemination of ideas to drug target discovery in biomedical problems. The difficulty lies at several levels: how to single out the role of individual elements in such intermingled systems, or which is the best way to quantify their importance. Centrality measures describe a node's importance by its position in a network. The key issue obviated is that the contribution of a node to the collective behavior is not uniquely determined by the structure of the system but it is a result of the interplay between dynamics and network structure. We show that dynamical influence measures explicitly how strongly a node's dynamical state affects collective behavior. For critical spreading, dynamical influence targets nodes according to their spreading capabilities. For diffusive processes it quantifies how efficiently real systems may be controlled by manipulating a single node.

  5. A measure of individual role in collective dynamics

    PubMed Central

    Klemm, Konstantin; Serrano, M. Ángeles; Eguíluz, Víctor M.; Miguel, Maxi San

    2012-01-01

    Identifying key players in collective dynamics remains a challenge in several research fields, from the efficient dissemination of ideas to drug target discovery in biomedical problems. The difficulty lies at several levels: how to single out the role of individual elements in such intermingled systems, or which is the best way to quantify their importance. Centrality measures describe a node's importance by its position in a network. The key issue obviated is that the contribution of a node to the collective behavior is not uniquely determined by the structure of the system but it is a result of the interplay between dynamics and network structure. We show that dynamical influence measures explicitly how strongly a node's dynamical state affects collective behavior. For critical spreading, dynamical influence targets nodes according to their spreading capabilities. For diffusive processes it quantifies how efficiently real systems may be controlled by manipulating a single node. PMID:22379597

  6. The New Pelagic Operational Observatory of the Catalan Sea (OOCS) for the Multisensor Coordinated Measurement of Atmospheric and Oceanographic Conditions

    PubMed Central

    Bahamon, Nixon; Aguzzi, Jacopo; Bernardello, Raffaele; Ahumada-Sempoal, Miguel-Angel; Puigdefabregas, Joan; Cateura, Jordi; Muñoz, Eduardo; Velásquez, Zoila; Cruzado, Antonio

    2011-01-01

    The new pelagic Operational Observatory of the Catalan Sea (OOCS) for the coordinated multisensor measurement of atmospheric and oceanographic conditions has been recently installed (2009) in the Catalan Sea (41°39′N, 2°54′E; Western Mediterranean) and continuously operated (with minor maintenance gaps) until today. This multiparametric platform is moored at 192 m depth, 9.3 km off Blanes harbour (Girona, Spain). It is composed of a buoy holding atmospheric sensors and a set of oceanographic sensors measuring the water conditions over the upper 100 m depth. The station is located close to the head of the Blanes submarine canyon where an important multispecies pelagic and demersal fishery gives the station ecological and economic relevance. The OOCS provides important records on atmospheric and oceanographic conditions, the latter through the measurement of hydrological and biogeochemical parameters, at depths with a time resolution never attained before for this area of the Mediterranean. Twenty four moored sensors and probes operating in a coordinated fashion provide important data on Essential Ocean Variables (EOVs; UNESCO) such as temperature, salinity, pressure, dissolved oxygen, chlorophyll fluorescence, and turbidity. In comparison with other pelagic observatories presently operating in other world areas, OOCS also measures photosynthetic available radiation (PAR) from above the sea surface and at different depths in the upper 50 m. Data are recorded each 30 min and transmitted in real-time to a ground station via GPRS. This time series is published and automatically updated at the frequency of data collection on the official OOCS website (http://www.ceab.csic.es/~oceans). Under development are embedded automated routines for the in situ data treatment and assimilation into numerical models, in order to provide a reliable local marine processing forecast. In this work, our goal is to detail the OOCS multisensor architecture in relation to the

  7. The new pelagic Operational Observatory of the Catalan Sea (OOCS) for the multisensor coordinated measurement of atmospheric and oceanographic conditions.

    PubMed

    Bahamon, Nixon; Aguzzi, Jacopo; Bernardello, Raffaele; Ahumada-Sempoal, Miguel-Angel; Puigdefabregas, Joan; Cateura, Jordi; Muñoz, Eduardo; Velásquez, Zoila; Cruzado, Antonio

    2011-01-01

    The new pelagic Operational Observatory of the Catalan Sea (OOCS) for the coordinated multisensor measurement of atmospheric and oceanographic conditions has been recently installed (2009) in the Catalan Sea (41°39'N, 2°54'E; Western Mediterranean) and continuously operated (with minor maintenance gaps) until today. This multiparametric platform is moored at 192 m depth, 9.3 km off Blanes harbour (Girona, Spain). It is composed of a buoy holding atmospheric sensors and a set of oceanographic sensors measuring the water conditions over the upper 100 m depth. The station is located close to the head of the Blanes submarine canyon where an important multispecies pelagic and demersal fishery gives the station ecological and economic relevance. The OOCS provides important records on atmospheric and oceanographic conditions, the latter through the measurement of hydrological and biogeochemical parameters, at depths with a time resolution never attained before for this area of the Mediterranean. Twenty four moored sensors and probes operating in a coordinated fashion provide important data on Essential Ocean Variables (EOVs; UNESCO) such as temperature, salinity, pressure, dissolved oxygen, chlorophyll fluorescence, and turbidity. In comparison with other pelagic observatories presently operating in other world areas, OOCS also measures photosynthetic available radiation (PAR) from above the sea surface and at different depths in the upper 50 m. Data are recorded each 30 min and transmitted in real-time to a ground station via GPRS. This time series is published and automatically updated at the frequency of data collection on the official OOCS website (http://www.ceab.csic.es/~oceans). Under development are embedded automated routines for the in situ data treatment and assimilation into numerical models, in order to provide a reliable local marine processing forecast. In this work, our goal is to detail the OOCS multisensor architecture in relation to the coordinated

  8. Measuring geocentric radial coordinates with a non-fiducial GPS network

    NASA Astrophysics Data System (ADS)

    Rius, A.; Juan, J. M.; Hernández-Pajares, M.; Madrigal, A. M.

    1995-12-01

    In this paper we address the problem of estimating the short term precision of the geocentric radial coordinate of a GPS receiver placed on the Earth crust using a non-fiducial approach. The network used in our analysis contains 35 receivers distributed globally. We have analyzed the data with two different strategies: global and regional. In the global strategy the results obtained, which are compatible with those of Heflin et al. (1992) and Blewitt et al. (1992), provide a weighted root mean square of the residuals ( wrms) one order of magnitude larger than the formal errors of the individual estimates. Our regional strategy is based on the assumption that errors in the orbit determination induce errors in the receiver positions, correlated up to large scales. This approach allows us to obtain a significant agreement between the wrms and the formal errors.

  9. Recent THEMIS and Coordinated GBO Measurements of Substorm Expansion Onset: Do We Finally Have an Answer?

    NASA Technical Reports Server (NTRS)

    Kepko, L.

    2011-01-01

    For nearly 30 years an often-times heated debate has engaged the substorm community: Do substorms begin with the formation of a new reconnection site in the midtail plasma sheet (the Near-Earth Neutral Line model) or do they begin near the transition region between stretched tail and dipolar field lines (the Current Disruption model). The THEMIS mission, with a coordinated suite of five in-situ spacecraft and ground observatories, has greatly extended our understanding of how substorms initiate and evolve. But have the new data resolved the fundamental question? In this talk I review the last few year's of sub storm research, with an emphasis of how the THEMIS data have revolutionized our understanding.

  10. Recent Themis and Coordinated GBO Measurements of Substorm Expansion Onset: Do We Finally Have an Answer?

    NASA Technical Reports Server (NTRS)

    Kepko, Larry

    2011-01-01

    For nearly 30 years an often-times heated debate has engaged the substorm community: Do substorms begin with the formation of a new reconnection site in the midtail plasmasheet (the Near-Earth Neutral Line model) or do they begin near the transition region between stretched tail and dipolar field lines (the Current Disruption model). The THEMIS mission, with a coordinated suite of five in-situ spacecraft and ground observatories. has greatly extended our understanding of how substorms initiate and evolve. But have the new data resolved the fundamental question? In this talk I review the last few year's of substorm research, with an emphasis of how the THEMIS data have revolutionized our understanding.

  11. Making Scents: Dynamic Olfactometry for Threshold Measurement

    PubMed Central

    Schmidt, Roland

    2010-01-01

    Data on human odor thresholds show disparities huge enough to marginalize olfactory psychophysics and delegitimize importation of its data into other areas. Variation of orders of magnitude from study to study, much of it systematic, threatens meaningful comparisons with animal species, comparison between in vivo with in vitro studies, the search for molecular determinants of potency, and use of olfactory information for environmental or public health policy. On the premise that good experimental results will flow from use of good tools, this report describes a vapor delivery system and its peripherals that instantiate good tools. The vapor delivery device 8 (VDD8) provides flexibility in range of delivered concentrations, offers definable stability of delivery, accommodates solvent-free delivery below a part per trillion, gives a realistic interface with subjects, has accessible and replaceable components, and adapts to a variety of psychophysical methodologies. The device serves most often for measurement of absolute sensitivity, where its design encourages collection of thousands of judgments per day from subjects tested simultaneously. The results have shown humans to be more sensitive and less variable than has previous testing. The VDD8 can also serve for measurement of differential sensitivity, discrimination of quality, and perception of mixtures and masking. The exposition seeks to transmit general lessons while it proffers some specifics of design to reproduce features of the device in a new or existing system. The principles can apply to devices for animal testing. PMID:19965900

  12. Dynamic eye phantom for retinal oximetry measurements

    PubMed Central

    Lemaillet, Paul; Ramella-Roman, Jessica C.

    2009-01-01

    Measurements of oxygen saturation and flow in the retina can yield information about eye health and the onset of eye pathologies such as diabetic retinopathy. Recently, we developed a multiaperture camera that uses the division of the retinal image into several wavelength-sensitive subimages to compute retinal oxygen saturation. The calibration of such instruments is particularly difficult due to the layered structure of the eye and the lack of alternative measurement techniques. For this purpose, we realize an in vitro model of the human eye composed of a lens, the retina vessel, and three layers: the choroid, the retinal pigmented epithelium, and the sclera. The retinal vessel is modeled with a microtube connected to a micropump and a hemoglobin reservoir in a closed circulatory system. Hemoglobin oxygenation in the vessel could be altered using a reversible fuel cell. The sclera is represented by a Spectralon slab. The optical properties of the other layers are mimicked using titanium dioxide as a scatterer, ink as an absorber, and epoxy as a supporting structure. The optical thickness of each layer of the eye phantom is matched to each respective eye layer. PMID:20059246

  13. Dynamic eye phantom for retinal oximetry measurements.

    PubMed

    Lemaillet, Paul; Ramella-Roman, Jessica C

    2009-01-01

    Measurements of oxygen saturation and flow in the retina can yield information about eye health and the onset of eye pathologies such as diabetic retinopathy. Recently, we developed a multiaperture camera that uses the division of the retinal image into several wavelength-sensitive subimages to compute retinal oxygen saturation. The calibration of such instruments is particularly difficult due to the layered structure of the eye and the lack of alternative measurement techniques. For this purpose, we realize an in vitro model of the human eye composed of a lens, the retina vessel, and three layers: the choroid, the retinal pigmented epithelium, and the sclera. The retinal vessel is modeled with a microtube connected to a micropump and a hemoglobin reservoir in a closed circulatory system. Hemoglobin oxygenation in the vessel could be altered using a reversible fuel cell. The sclera is represented by a Spectralon slab. The optical properties of the other layers are mimicked using titanium dioxide as a scatterer, ink as an absorber, and epoxy as a supporting structure. The optical thickness of each layer of the eye phantom is matched to each respective eye layer.

  14. Dynamic eye phantom for retinal oximetry measurements

    NASA Astrophysics Data System (ADS)

    Lemaillet, Paul; Ramella-Roman, Jessica C.

    2009-11-01

    Measurements of oxygen saturation and flow in the retina can yield information about eye health and the onset of eye pathologies such as diabetic retinopathy. Recently, we developed a multiaperture camera that uses the division of the retinal image into several wavelength-sensitive subimages to compute retinal oxygen saturation. The calibration of such instruments is particularly difficult due to the layered structure of the eye and the lack of alternative measurement techniques. For this purpose, we realize an in vitro model of the human eye composed of a lens, the retina vessel, and three layers: the choroid, the retinal pigmented epithelium, and the sclera. The retinal vessel is modeled with a microtube connected to a micropump and a hemoglobin reservoir in a closed circulatory system. Hemoglobin oxygenation in the vessel could be altered using a reversible fuel cell. The sclera is represented by a Spectralon slab. The optical properties of the other layers are mimicked using titanium dioxide as a scatterer, ink as an absorber, and epoxy as a supporting structure. The optical thickness of each layer of the eye phantom is matched to each respective eye layer.

  15. Emergence of Rich-Club Topology and Coordinated Dynamics in Development of Hippocampal Functional Networks In Vitro

    PubMed Central

    Charlesworth, Paul; Kitzbichler, Manfred G.; Paulsen, Ole

    2015-01-01

    Recent studies demonstrated that the anatomical network of the human brain shows a “rich-club” organization. This complex topological feature implies that highly connected regions, hubs of the large-scale brain network, are more densely interconnected with each other than expected by chance. Rich-club nodes were traversed by a majority of short paths between peripheral regions, underlining their potential importance for efficient global exchange of information between functionally specialized areas of the brain. Network hubs have also been described at the microscale of brain connectivity (so-called “hub neurons”). Their role in shaping synchronous dynamics and forming microcircuit wiring during development, however, is not yet fully understood. The present study aimed to investigate the role of hubs during network development, using multi-electrode arrays and functional connectivity analysis during spontaneous multi-unit activity (MUA) of dissociated primary mouse hippocampal neurons. Over the first 4 weeks in vitro, functional connectivity significantly increased in strength, density, and size, with mature networks demonstrating a robust modular and small-world topology. As expected by a “rich-get-richer” growth rule of network evolution, MUA graphs were found to form rich-clubs at an early stage in development (14 DIV). Later on, rich-club nodes were a consistent topological feature of MUA graphs, demonstrating high nodal strength, efficiency, and centrality. Rich-club nodes were also found to be crucial for MUA dynamics. They often served as broker of spontaneous activity flow, confirming that hub nodes and rich-clubs may play an important role in coordinating functional dynamics at the microcircuit level. PMID:25855164

  16. Pointwise fiber Bragg grating displacement sensor system for dynamic measurements.

    PubMed

    Chuang, Kuo-Chih; Ma, Chien-Ching

    2008-07-10

    A method for setting up a fiber Bragg grating (FBG) sensor which can measure the pointwise, out-of-plane or in-plane dynamic displacement is proposed. The proposed FBG sensor is reusable. A multiplexing demodulation system based on a single long-period fiber grating is used in this study. The experimental results of the steady-state motion for a multilayer piezoelectric actuator and the dynamic response of a cantilever beam subjected to impact loadings are presented. These results indicate that the proposed displacement sensor has the ability to measure the out-of-plane dynamic displacement with high sensitivity. Measurements for a piezoceramic plate excited by high frequency show that the proposed displacement sensor also has the ability to provide the in-plane dynamic displacement up to 20 kHz.

  17. Dynamic Engagement of Human Motion Detectors across Space–Time Coordinates

    PubMed Central

    2014-01-01

    Motion detection is a fundamental property of the visual system. The gold standard for studying and understanding this function is the motion energy model. This computational tool relies on spatiotemporally selective filters that capture the change in spatial position over time afforded by moving objects. Although the filters are defined in space–time, their human counterparts have never been studied in their native spatiotemporal space but rather in the corresponding frequency domain. When this frequency description is back-projected to spatiotemporal description, not all characteristics of the underlying process are retained, leaving open the possibility that important properties of human motion detection may have remained unexplored. We derived descriptors of motion detectors in native space–time, and discovered a large unexpected dynamic structure involving a >2× change in detector amplitude over the first ∼100 ms. This property is not predicted by the energy model, generalizes across the visual field, and is robust to adaptation; however, it is silenced by surround inhibition and is contrast dependent. We account for all results by extending the motion energy model to incorporate a small network that supports feedforward spread of activation along the motion trajectory via a simple gain-control circuit. PMID:24948800

  18. Dynamic gas temperature measurement system, volume 1

    NASA Technical Reports Server (NTRS)

    Elmore, D. L.; Robinson, W. W.; Watkins, W. B.

    1983-01-01

    A gas temperature measurement system with compensated frequency response of 1 kHz and capability to operate in the exhaust of a gas turbine engine combustor was developed. A review of available technologies which could attain this objective was done. The most promising method was identified as a two wire thermocouple, with a compensation method based on the responses of the two different diameter thermocouples to the fluctuating gas temperature field. In a detailed design of the probe, transient conduction effects were identified as significant. A compensation scheme was derived to include the effects of gas convection and wire conduction. The two wire thermocouple concept was tested in a laboratory burner exhaust to temperatures of about 3000 F and in a gas turbine engine to combustor exhaust temperatures of about 2400 F. Uncompensated and compensated waveforms and compensation spectra are presented.

  19. Measuring Dynamic Patterns in the Structure of Substate Economies.

    ERIC Educational Resources Information Center

    McHugh, Richard; And Others

    The objective of this study was to explore a new method of analyzing the performance of substate economies. Conventional analyses of economic diversity and growth are limited by their reliance on static measures of economic structure. Such measures do not capture the patterns of growth dynamics or structural change a region may be experiencing.…

  20. Vertical dynamic deflection measurement in concrete beams with the Microsoft Kinect.

    PubMed

    Qi, Xiaojuan; Lichti, Derek; El-Badry, Mamdouh; Chow, Jacky; Ang, Kathleen

    2014-02-19

    The Microsoft Kinect is arguably the most popular RGB-D camera currently on the market, partially due to its low cost. It offers many advantages for the measurement of dynamic phenomena since it can directly measure three-dimensional coordinates of objects at video frame rate using a single sensor. This paper presents the results of an investigation into the development of a Microsoft Kinect-based system for measuring the deflection of reinforced concrete beams subjected to cyclic loads. New segmentation methods for object extraction from the Kinect's depth imagery and vertical displacement reconstruction algorithms have been developed and implemented to reconstruct the time-dependent displacement of concrete beams tested in laboratory conditions. The results demonstrate that the amplitude and frequency of the vertical displacements can be reconstructed with submillimetre and milliHz-level precision and accuracy, respectively.

  1. Vertical Dynamic Deflection Measurement in Concrete Beams with the Microsoft Kinect

    PubMed Central

    Qi, Xiaojuan; Lichti, Derek; El-Badry, Mamdouh; Chow, Jacky; Ang, Kathleen

    2014-01-01

    The Microsoft Kinect is arguably the most popular RGB-D camera currently on the market, partially due to its low cost. It offers many advantages for the measurement of dynamic phenomena since it can directly measure three-dimensional coordinates of objects at video frame rate using a single sensor. This paper presents the results of an investigation into the development of a Microsoft Kinect-based system for measuring the deflection of reinforced concrete beams subjected to cyclic loads. New segmentation methods for object extraction from the Kinect's depth imagery and vertical displacement reconstruction algorithms have been developed and implemented to reconstruct the time-dependent displacement of concrete beams tested in laboratory conditions. The results demonstrate that the amplitude and frequency of the vertical displacements can be reconstructed with submillimetre and milliHz-level precision and accuracy, respectively. PMID:24556668

  2. Coordinated ground-based and geosynchronous satellite-based measurements of auroral pulsations

    SciTech Connect

    Suszcynsky, David M.; Borovsky, Joseph E.; Thomsen, Michelle F.; McComas, David J.; Belian, Richard D.

    1996-09-01

    We describe a technique that uses a ground-based all-sky video camera and geosynchronous satellite-based plasma and energetic particle detectors to study ionosphere-magnetosphere coupling as it relates to the aurora. The video camera system was deployed in Eagle, Alaska for a seven month period at the foot of the magnetic field line that threads geosynchronous satellite 1989-046. Since 1989-046 corotates with the earth, its footprint remains nearly fixed in the vicinity of Eagle, allowing for routine continuous monitoring of an auroral field line at its intersections with the ground and with geosynchronous orbit. As an example of the utility of this technique, we present coordinated ground-based and satellite based observations during periods of auroral pulsations and compare this data to the predictions of both the relaxation oscillator theory and flow cyclotron maser theory for the generation of pulsating aurorae. The observed plasma and energetic particle characteristics at geosynchronous orbit during pulsating aurorae displays are found to be in agreement with the predictions of both theories lending further support that a cyclotron resonance mechanism is responsible for auroral pulsations.

  3. Essential Measures for Student Success: Implementing Cooperation, Collaboration, and Coordination between Schools and Parents

    ERIC Educational Resources Information Center

    Kirby, Edwena

    2012-01-01

    This book unveils "essential measures" that create a revitalized educational system of which educators and parents can use to promote student success. When these measures are applied properly, the benefits include, eradicating student fear, elevating student motivation, improving school attendance, and reducing student dropout rates. These…

  4. Cumulative Measurement Errors for Dynamic Testing of Space Flight Hardware

    NASA Technical Reports Server (NTRS)

    Winnitoy, Susan

    2012-01-01

    Located at the NASA Johnson Space Center in Houston, TX, the Six-Degree-of-Freedom Dynamic Test System (SDTS) is a real-time, six degree-of-freedom, short range motion base simulator originally designed to simulate the relative dynamics of two bodies in space mating together (i.e., docking or berthing). The SDTS has the capability to test full scale docking and berthing systems utilizing a two body dynamic docking simulation for docking operations and a Space Station Remote Manipulator System (SSRMS) simulation for berthing operations. The SDTS can also be used for nonmating applications such as sensors and instruments evaluations requiring proximity or short range motion operations. The motion base is a hydraulic powered Stewart platform, capable of supporting a 3,500 lb payload with a positional accuracy of 0.03 inches. The SDTS is currently being used for the NASA Docking System testing and has been also used by other government agencies. The SDTS is also under consideration for use by commercial companies. Examples of tests include the verification of on-orbit robotic inspection systems, space vehicle assembly procedures and docking/berthing systems. The facility integrates a dynamic simulation of on-orbit spacecraft mating or de-mating using flight-like mechanical interface hardware. A force moment sensor is used for input during the contact phase, thus simulating the contact dynamics. While the verification of flight hardware presents unique challenges, one particular area of interest involves the use of external measurement systems to ensure accurate feedback of dynamic contact. The measurement systems for the test facility have two separate functions. The first is to take static measurements of facility and test hardware to determine both the static and moving frames used in the simulation and control system. The test hardware must be measured after each configuration change to determine both sets of reference frames. The second function is to take dynamic

  5. High-speed scanning of critical structures in aviation using coordinate measurement machine and the laser ultrasonic.

    PubMed

    Swornowski, Pawel J

    2012-01-01

    Aviation is one of the know-how spheres containing a great deal of responsible sub-assemblies, in this case landing gear. The necessity for reducing production cycle times while achieving better quality compels metrologists to look for new and improved ways to perform inspection of critical structures. This article describes the ability to determine the shape deviation and location of defects in landing gear using coordinate measuring machines and laser ultrasonic with high-speed scanning. A nondestructive test is the basis for monitoring microcrack and corrosion propagation in the context of a damage-tolerant design approach. This article presents an overview of the basics and of the various metrological aspects of coordinate measurement and a nondestructive testing method in terms of high-speed scanning. The new test method (laser ultrasonic) promises to produce the necessary increase in inspection quality, but this is limited by the wide range of materials, geometries, and structure aeronautic parts used. A technique combining laser ultrasonic and F-SAFT (Fourier-Synthetic Aperture Focusing Technique) processing has been proposed for the detection of small defects buried in landing gear. The experimental results of landing gear inspection are also presented.

  6. Furthur development of the dynamic gas temperature measurement system

    NASA Technical Reports Server (NTRS)

    Elmore, D. L.; Robinson, W. W.; Watkins, W. B.

    1984-01-01

    Candidate concepts capable of generating dynamic temperatures were identified and analyzed for use in verifying experimentally the frequency response of the dynamic gas temperature measurement system. A rotating wheel concept and one other concept will be selected for this purpose. Modifications to the data reduction code algorithms developed were identified and evaluated to reduce substantially the data reduction execution time. These modifications will be incorporated in a new data reduction program to be written in FORTRAN IV.

  7. Dual redundant arm system operational quality measures and their applications - Dynamic measures

    NASA Technical Reports Server (NTRS)

    Lee, Sukhan; Kim, Sungbok

    1990-01-01

    Dual-arm dynamic operation quality measures are presented which quantify the efficiency and capability of generating Cartesian accelerations by two cooperative arms based on the analysis of dual-arm dynamic interactions. Dual-arm dynamic manipulability is defined as the efficiency of generating Cartesian accelerations under the dynamic and kinematic interactions between individual arms and an object under manipulation. The analysis of dual-arm dynamic interactions is based on the so-called Cartesian space agent model of an arm, which represents an individual arm as a force source acting upon a point mass with the effective Cartesian space arm dynamics and an environment or an object under manipulation. The Cartesian space agent model of an arm makes it possible to derive the dynamic and kinematic constraints involved in the transport, assembly and grasping modes of dual-arm cooperation. A task-oriented operational quality measure, (TOQd) is defined by evaluating dual-arm dynamic manipulability in terms of given task requirements. TOQd is used in dual-arm joint configuration optimization. Simulation results are shown. A complete set of forward dynamic equations for a dual-arm system is derived, and dual-arm dynamic operational quality measures for various modes of dual-arm cooperation allowing sliding contacts are established.

  8. Coordination numbers of K(+) and Na(+) Ions inside the selectivity filter of the KcsA potassium channel: insights from first principles molecular dynamics.

    PubMed

    Bucher, Denis; Guidoni, Leonardo; Carloni, Paolo; Rothlisberger, Ursula

    2010-05-19

    Quantum mechanics/molecular mechanics (QM/MM) Car-Parrinello simulations were performed to estimate the coordination numbers of K(+) and Na(+) ions in the selectivity filter of the KcsA channel, and in water. At the DFT/BLYP level, K(+) ions were found to display an average coordination number of 6.6 in the filter, and 6.2 in water. Na(+) ions displayed an average coordination number of 5.2 in the filter, and 5.0 in water. A comparison was made with the average coordination numbers obtained from using classical molecular dynamics (6.7 for K(+) in the filter, 6.6 for K(+) in water, 6.0 for Na(+) in the filter, and 5.2 for Na(+) in water). The observation that different coordination numbers were displayed by the ions in QM/MM simulations and in classical molecular dynamics is relevant to the discussion of selectivity in K-channels.

  9. Hydrothermal alteration and diagenesis of terrestrial lacustrine pillow basalts: Coordination of hyperspectral imaging with laboratory measurements

    USGS Publications Warehouse

    Greenberger, Rebecca N; Mustard, John F; Cloutis, Edward A; Mann, Paul; Wilson, Janette H.; Flemming, Roberta L; Robertson, Kevin; Salvatore, Mark R; Edwards, Christopher

    2015-01-01

    The phases identified in the sample are albite, large iron oxides, and titanite throughout; calcite in vesicles; calcic clinopyroxene, aegirine, and Fe/Mg-bearing clay in the rind; and fine-grained hematite and pyroxenes in the interior. Using imaging spectroscopy, the chemistry and mineralogy results extend to the hand sample and larger outcrop. From all of the analyses, we suggest that the pillow basalts were altered initially after emplacement, either by heated lake water or magmatic fluids, at temperatures of at least 400-600°C, and the calcic clinopyroxenes and aegirine identified in the rind are a preserved record of that alteration. As the hydrothermal system cooled to slightly lower temperatures, clays formed in the rind, and, during this alteration, the sample oxidized to form hematite in the matrix of the interior and Fe3+ in the pyroxenes in the rind. During the waning stages of the hydrothermal system, calcite precipitated in vesicles within the rind. Later, diagenetic processes albitized the sample, with albite replacing plagioclase, lining vesicles, and accreting onto the exterior of the sample. This albitization or Na-metasomatism occurred when the lake within the Hartford Basin evaporated during a drier past climatic era, resulting in Na-rich brines. As Ca-rich plagioclase altered to albite, Ca was released into solution, eventually precipitating as calcite in previously-unfilled vesicles, dominantly in the interior of the pillow. Coordinated analyses of this sample permit identification of the alteration phases and help synthesize the aqueous history of pillow lavas of the Talcott formation. These results are also relevant to Mars, where volcanically-resurfaced open basin lakes have been found, and this Hartford Basin outcrop may be a valuable analog for any potential volcano-lacustrine interactions. The results can also help to inform the utility and optimization of potentially complementary, synergistic, and uniquely-suited techniques for

  10. The dynamics of the tundra-taiga boundary: an overview and suggested coordinated and integrated approach to research.

    PubMed

    Callaghan, Terry V; Crawford, Robert M M; Eronen, Matti; Hofgaard, Annika; Payette, Serge; Rees, W Gareth; Skre, Oddvar; Sveinbjörnsson, Bjartmar; Vlassova, Tatiana K; Werkman, Ben R

    2002-08-01

    The tundra-taiga boundary stretches for more than 13,400 km around the Northern Hemisphere and is probably the Earth's greatest vegetation transition. The trees that define the boundary have been sensitive to climate changes in the past and models of future vegetation distribution suggest a rapid and dramatic invasion of the tundra by the taiga. Such changes would generate both positive and negative feedbacks to the climate system and the balance could result in a net warming effect. However, the boundary is becoming increasingly affected by human activities that remove trees and degrade forest-tundra into tundra-like areas. Because of the vastness and remoteness of the tundra-taiga boundary, and of methodological problems such as problematic definitions and lack of standardized methods to record the location and characteristics of the ecotone, a project group has been established under the auspices of the International Arctic Science Committee (IASC). This paper summarizes the initial output of the group and focuses on our uncertainties in understanding the current processes at the tundra-taiga boundary and the conflicts between model predictions of changes in the location of the boundary and contrasting recently observed changes due to human activities. Finally, we present recommendations for a coordinated international approach to the problem and invite the international community to join us in reducing the uncertainties about the dynamics of the ecotone and their consequences.

  11. Coordinated analysis of various auroral measurements made during NASA's 1968 and 1969 airborne auroral expeditions

    NASA Technical Reports Server (NTRS)

    Sivjee, G. G.

    1976-01-01

    Auroral optical measurements made aboard NASA's CV 990 were analyzed. The measurements analyzed form a small part of extensive spectroscopic, photometric and photographic data gathered during the 1968 and 1969 Airborne Auroral Expeditions. Simultaneous particle measurements from ESRO IA satellite were used in the analysis. Information about magnetospheric boundaries, interaction between magnetosheath particles and the terrestrial ionosphere, the polar bulge in helium abundance and excitation mechanisms of the triplet state of atmospheric N2 in auroras was obtained. Further analysis of the data is required to elucidate the relation between 3466 and 5200 A emissions of NI and the excitation of 3726-3729 A emissions from atomic oxygen ions in auroras.

  12. Effects of Coordinate Rotation and Averaging Period on Energy Closure Characteristics of Eddy Covariance Measurements over Mountainous Terrain

    NASA Astrophysics Data System (ADS)

    Li, M.; Chen, Y.

    2009-12-01

    Coordinate rotation is typically applied to align measured turbulence data along the stream wise direction before calculating turbulent fluxes. A standard averaging period (30 min) is commonly used when estimating these fluxes. Different rotation approaches with various averaging periods can cause systemic bias and significant variations in flux estimations. Thus, measuring surface fluxes over a non-flat terrain requires that an appropriate rotation technique and optimal averaging period are applied. In this study, two coordinate rotation approaches (double and planar-fit rotations) and no-rotation, in associated with averaging periods of 15-240 min, were applied to compute heat and water vapor fluxes over a mountainous terrain using the eddy covariance method. Measurements were conducted in an experimental watershed, the Lien-Hua-Chih (LHC) watershed, located in the central Taiwan. This watershed has considerable meso-scale circulation and mountainous terrain. Vegetation type is a mixture of natural deciduous forest and shrubs; canopy height is about 17 m. A 22 m tall observation tower was built inside the canopy. The prevailing wind direction is NW during daytime and ES during the night time at the LHC site in both the dry and wet seasons. Turbulence data above the canopy were measured with an eddy covariance system comprising a 3-D sonic anemometer (Young 81000) and a krypton hygrometer (Campbell KH20). Raw data of 10 Hz were recorded simultaneously with a data logger (CR1000) and a CF card. Air temperature/humidity profiles were measured to calculate the heat/moisture storage inside the canopy layer. Air pressure data were used to correct the effect of air density fluctuations on surface fluxes. The effects of coordinate rotation approaches with various averaging periods on the average daily energy closure fraction are presented. The criteria of the best energy closure fraction and minimum uncertainty indicate that planar-fit rotation with an averaging period

  13. Coordinated Airborne, Spaceborne, and Ground-Based Measurements of Massive, Thick Aerosol Layers During the Dry Season in Southern Africa

    NASA Technical Reports Server (NTRS)

    Schmid, B.; Redemann, J.; Russell, P. B.; Hobbs, P. V.; Hlavka, D. L.; McGill, M. J.; Holben, B. N.; Welton, E. J.; Campbell, J.; Torres, O.; Hipskind, R. Stephen (Technical Monitor)

    2002-01-01

    During the dry-season airborne campaign of the Southern African Regional Science Initiative (SAFARI 2000), unique coordinated observations were made of massive, thick aerosol layers. These layers were often dominated by aerosols from biomass burning. We report on airborne Sunphotometer measurements of aerosol optical depth (lambda=354-1558 nm), columnar water vapor, and vertical profiles of aerosol extinction and water vapor density that were obtained aboard the University of Washington's Convair-580 research aircraft. We compare these with ground-based AERONET Sun/sky radiometer results, with ground based lidar data MPL-Net), and with measurements from a downward-pointing lidar aboard the high-flying NASA ER-2 aircraft. Finally, we show comparisons between aerosol optical depths from the Sunphotometer and those retrieved over land and over water using four spaceborne sensors (TOMS (Total Ozone Mapping Spectrometer), MODIS (Moderate Resolution Imaging Spectrometer), MISR (Multiangle Imaging Spectroradiometer) and ATSR-2 (Along Track Scanning Radiometer)).

  14. Coordinated Airborne, Spaceborne and Ground-based Measurements of Massive Thick Aerosol Layers during the Dry Season in Southern Africa

    NASA Technical Reports Server (NTRS)

    Schmid, B.; Redemann, J.; Russell, P. B.; Hobbs, P. V.; Hlavka, D. L.; McGill, M. J.; Holben, B. N.; Welton, E. J.; Campbell, J. R.; Torres, O.

    2003-01-01

    During the dry season airborne campaign of the Southern African Regional Science Initiative (SAFARI 2000), coordinated observations were made of massive thick aerosol layers. These layers were often dominated by aerosols from biomass burning. We report on airborne Sun photometer measurements of aerosol optical depth (lambda = 0.354- 1.557 microns), columnar water vapor, and vertical profiles of aerosol extinction and water vapor density that were obtained aboard the University of Washington's Convair-580 research aircraft. We compare these with ground-based AERONET Sun/sky radiometer results, with ground based lidar data (MPL-Net), and with measurements from a downward pointing lidar aboard the high-flying NASA ER-2 aircraft. Finally, we show comparisons between aerosol optical depths fiom the Sun photometer and those retrieved over land and over water using four spaceborne sensors (TOMS, MODIS, MISR, and ATSR-2).

  15. Dynamic tire pressure sensor for measuring ground vibration.

    PubMed

    Wang, Qi; McDaniel, James Gregory; Wang, Ming L

    2012-11-07

    This work presents a convenient and non-contact acoustic sensing approach for measuring ground vibration. This approach, which uses an instantaneous dynamic tire pressure sensor (DTPS), possesses the capability to replace the accelerometer or directional microphone currently being used for inspecting pavement conditions. By measuring dynamic pressure changes inside the tire, ground vibration can be amplified and isolated from environmental noise. In this work, verifications of the DTPS concept of sensing inside the tire have been carried out. In addition, comparisons between a DTPS, ground-mounted accelerometer, and directional microphone are made. A data analysis algorithm has been developed and optimized to reconstruct ground acceleration from DTPS data. Numerical and experimental studies of this DTPS reveal a strong potential for measuring ground vibration caused by a moving vehicle. A calibration of transfer function between dynamic tire pressure change and ground acceleration may be needed for different tire system or for more accurate application.

  16. Dynamic Tire Pressure Sensor for Measuring Ground Vibration

    PubMed Central

    Wang, Qi; McDaniel, James Gregory; Wang, Ming L.

    2012-01-01

    This work presents a convenient and non-contact acoustic sensing approach for measuring ground vibration. This approach, which uses an instantaneous dynamic tire pressure sensor (DTPS), possesses the capability to replace the accelerometer or directional microphone currently being used for inspecting pavement conditions. By measuring dynamic pressure changes inside the tire, ground vibration can be amplified and isolated from environmental noise. In this work, verifications of the DTPS concept of sensing inside the tire have been carried out. In addition, comparisons between a DTPS, ground-mounted accelerometer, and directional microphone are made. A data analysis algorithm has been developed and optimized to reconstruct ground acceleration from DTPS data. Numerical and experimental studies of this DTPS reveal a strong potential for measuring ground vibration caused by a moving vehicle. A calibration of transfer function between dynamic tire pressure change and ground acceleration may be needed for different tire system or for more accurate application. PMID:23202206

  17. Rayleigh Scattering Diagnostic for Dynamic Measurement of Velocity and Temperature

    NASA Technical Reports Server (NTRS)

    Seasholtz, Richard G.; Panda, J.

    2001-01-01

    A new technique for measuring dynamic gas velocity and temperature is described. The technique is based on molecular Rayleigh scattering of laser light, so no seeding of the flow is necessary. The Rayleigh scattered light is filtered with a fixed cavity, planar mirror Fabry-Perot interferometer. A minimum number of photodetectors were used in order to allow the high data acquisition rate needed for dynamic measurements. One photomultiplier tube (PMT) was used to measure the total Rayleigh scattering, which is proportional to the gas density. Two additional PMTs were used to detect light that passes through two apertures in a mask located in the interferometer fringe plane. An uncertainty analysis was used to select the optimum aperture parameters and to predict the measurement uncertainty due to photon shot-noise. Results of an experiment to measure the velocity of a subsonic free jet are presented.

  18. Laser velocimetry measurements of oscillating airfoil dynamic stall flow field

    NASA Technical Reports Server (NTRS)

    Chandrasekhara, M. S.; Ahmed, S.

    1991-01-01

    Ensemble-averaged two-component velocity measurements over an airfoil experiencing oscillatory dynamic stall under compressibility conditions were obtained. The measurements show the formation of a separation bubble over the airfoil that persists till angles of attack close to when the dynamic stall vortex forms and convects. The fluid attains mean velocities as large as 1.6 times the free stream velocity with instantaneous values of 1.8 times the free stream velocity. The airfoil motion induces these large velocities in regions that are far removed from the surface.

  19. Coordinating outcomes measurement in ataxia research: do some widely used generic rating scales tick the boxes?

    PubMed

    Riazi, Afsane; Cano, Stefan J; Cooper, J Mark; Bradley, Jane L; Schapira, Anthony H V; Hobart, Jeremy C

    2006-09-01

    The objective of this study was to examine the psychometric properties of four widely used generic health status measures in Friedreich's ataxia (FA), to determine their suitability as outcome measures. Fifty-six people with genetically confirmed FA completed the Barthel Index (BI), General Health Questionnaire (GHQ-12), EuroQol (EQ-5D), and Medical Outcomes Study 36-item Short Form Health Survey (SF-36) by means of postal survey. Six psychometric properties (data quality, scaling assumptions, acceptability, reliability, validity, and responsiveness) were examined. The response rate was 97%. In general, the psychometric properties of the four measures satisfied recommended criteria. However, closer examination highlighted limitations restricting their use for treatment trials. For example, the BI had high levels of missing data, EQ-5D had poor discriminant ability, and five SF-36 scales had high floor and/or ceiling effects. Most scale scores did not span the entire scale range, had means that differed notably from the scale mid-point, and had wide confidence intervals. Effect sizes (ES) were small for all four measures raising questions about their ability to detect clinically significant change. Results highlight the potential limitations of these four scales for evaluating health outcomes in FA and suggest the need for new disease-specific patient-based measures of its impact.

  20. UARS MILS O3 soundings compared with lidar measurements using the conservative coordinates reconstruction technique

    NASA Technical Reports Server (NTRS)

    Redaelli, G.; Lait, L. R.; Schoeberl, M.; Newman, P. A.; Visconti, G.; D'Altorio, A.; Masci, F.; Rizi, V.; Froidevaux, L.; Waters, J. W.

    1994-01-01

    A technique based on conservative properties of certain meteorological fields is used to compare ozone measurements from the Microwave Limb Sounder (MLS) on the Upper Atmosphere Research Satellite (UARS) with soundings from a lidar system operated at midlatitudes by the University of L'Aquila, Italy. A few typical cases are analyzed in connection with the position of the vortex relative to the observing station, and it is shown that in general lidar observations taken within the vortex compare well with the UARS data, regardless of whether they are coincident with a satellite overpass. It is shown that such analysis may be useful for comparing measurements of the same quantity taken at different sites using different measurement techniques.

  1. Quantum dynamics of simultaneously measured non-commuting observables

    NASA Astrophysics Data System (ADS)

    Hacohen-Gourgy, Shay; Martin, Leigh S.; Flurin, Emmanuel; Ramasesh, Vinay V.; Whaley, K. Birgitta; Siddiqi, Irfan

    2016-10-01

    In quantum mechanics, measurements cause wavefunction collapse that yields precise outcomes, whereas for non-commuting observables such as position and momentum Heisenberg’s uncertainty principle limits the intrinsic precision of a state. Although theoretical work has demonstrated that it should be possible to perform simultaneous non-commuting measurements and has revealed the limits on measurement outcomes, only recently has the dynamics of the quantum state been discussed. To realize this unexplored regime, we simultaneously apply two continuous quantum non-demolition probes of non-commuting observables to a superconducting qubit. We implement multiple readout channels by coupling the qubit to multiple modes of a cavity. To control the measurement observables, we implement a ‘single quadrature’ measurement by driving the qubit and applying cavity sidebands with a relative phase that sets the observable. Here, we use this approach to show that the uncertainty principle governs the dynamics of the wavefunction by enforcing a lower bound on the measurement-induced disturbance. Consequently, as we transition from measuring identical to measuring non-commuting observables, the dynamics make a smooth transition from standard wavefunction collapse to localized persistent diffusion and then to isotropic persistent diffusion. Although the evolution of the state differs markedly from that of a conventional measurement, information about both non-commuting observables is extracted by keeping track of the time ordering of the measurement record, enabling quantum state tomography without alternating measurements. Our work creates novel capabilities for quantum control, including rapid state purification, adaptive measurement, measurement-based state steering and continuous quantum error correction. As physical systems often interact continuously with their environment via non-commuting degrees of freedom, our work offers a way to study how notions of contemporary

  2. Coordinated analysis of airborne spectrophotometric measurements from the mid-day auroras

    NASA Technical Reports Server (NTRS)

    Sivjee, G. G.

    1974-01-01

    Measurements made in the midday auroras are analyzed and compared to measurements from the nighttime auroras. The auroral emission features in the UV spectrum, the N2(+)ING, the N22PG, and N2VK bands, are discussed. Spectral profiles of different bands are presented, and intensity distributions are obtained. Three mechanisms are suggested which can account for the marked differences between the intensity distributions of the N2(+)ING bands of the high altitude midday auroras and the low altitude nighttime auroras: (1) differences in vibrational, rotational, and transitional temperatures; (2) resonant scattering of solar radiation; and (3) excitation of slow ions.

  3. Coordinated underground measurements of gamma-ray emitting radionuclides for plasma physics research.

    PubMed

    Tzika, Faidra; Hult, Mikael; Fenyvesi, András; Bandac, Iulian; Degering, Detlev; Ianni, Aldo; Laubenstein, Matthias; de Vismes-Ott, Anne; Marissens, Gerd; Stroh, Heiko; Lutter, Guillaume; Son, Soohyun; Hong, Suk-Ho; Kim, Jun Young; Kim, Junghee; Cheon, Mun Seung; Jo, Jungmin; Braun, Mihály; Németh, József; Zoletnik, Sándor; Bonheure, Georges

    2016-12-24

    Forty-eight samples made of CaF2, LiF and YVO4 were placed inside the KSTAR Tokamak and irradiated by neutrons and charged particles from eight plasma pulses. The aim was to provide information for plasma diagnostics. Due to the short pulse durations, the activities induced in the samples were low and therefore measurements were performed in five low-background underground laboratories. Details of the underground measurements, together with data on the quality control amongst the radiometric laboratories, are presented.

  4. A theory of neural dimensionality, dynamics, and measurement

    NASA Astrophysics Data System (ADS)

    Ganguli, Surya

    In many experiments, neuroscientists tightly control behavior, record many trials, and obtain trial-averaged firing rates from hundreds of neurons in circuits containing millions of behaviorally relevant neurons. Dimensionality reduction has often shown that such datasets are strikingly simple; they can be described using a much smaller number of dimensions than the number of recorded neurons, and the resulting projections onto these dimensions yield a remarkably insightful dynamical portrait of circuit computation. This ubiquitous simplicity raises several profound and timely conceptual questions. What is the origin of this simplicity and its implications for the complexity of brain dynamics? Would neuronal datasets become more complex if we recorded more neurons? How and when can we trust dynamical portraits obtained from only hundreds of neurons in circuits containing millions of neurons? We present a theory that answers these questions, and test it using neural data recorded from reaching monkeys. Overall, this theory yields a picture of the neural measurement process as a random projection of neural dynamics, conceptual insights into how we can reliably recover dynamical portraits in such under-sampled measurement regimes, and quantitative guidelines for the design of future experiments. Moreover, it reveals the existence of phase transition boundaries in our ability to successfully decode cognition and behavior as a function of the number of recorded neurons, the complexity of the task, and the smoothness of neural dynamics. membership pending.

  5. An innovative method for coordinate measuring machine one-dimensional self-calibration with simplified experimental process.

    PubMed

    Fang, Cheng; Butler, David Lee

    2013-05-01

    In this paper, an innovative method for CMM (Coordinate Measuring Machine) self-calibration is proposed. In contrast to conventional CMM calibration that relies heavily on a high precision reference standard such as a laser interferometer, the proposed calibration method is based on a low-cost artefact which is fabricated with commercially available precision ball bearings. By optimizing the mathematical model and rearranging the data sampling positions, the experimental process and data analysis can be simplified. In mathematical expression, the samples can be minimized by eliminating the redundant equations among those configured by the experimental data array. The section lengths of the artefact are measured at arranged positions, with which an equation set can be configured to determine the measurement errors at the corresponding positions. With the proposed method, the equation set is short of one equation, which can be supplemented by either measuring the total length of the artefact with a higher-precision CMM or calibrating the single point error at the extreme position with a laser interferometer. In this paper, the latter is selected. With spline interpolation, the error compensation curve can be determined. To verify the proposed method, a simple calibration system was set up on a commercial CMM. Experimental results showed that with the error compensation curve uncertainty of the measurement can be reduced to 50%.

  6. Scale-Independent Measures and Pathologic Cardiac Dynamics

    NASA Astrophysics Data System (ADS)

    Amaral, Luís A.; Goldberger, Ary L.; Ivanov, Plamen Ch.; Stanley, H. Eugene

    1998-09-01

    We study several scale-independent measures of cardiac interbeat interval dynamics defined through the application of the wavelet transform. We test their performance in detecting heart disease using a database consisting of records of interbeat intervals for a group of healthy individuals and subjects with congestive heart failure. We find that scale-independent measures effectively distinguish healthy from pathologic behavior and propose a new two-variable scale-independent measure that could be clinically useful. We compare the performance of a recently proposed scale-dependent measure and find that the results depend on the database analyzed and on the analyzing wavelet.

  7. Objective and automated measurement of dynamic vision functions

    NASA Technical Reports Server (NTRS)

    Flom, M. C.; Adams, A. J.

    1976-01-01

    A phoria stimulus array and electro-oculographic (EOG) arrangements for measuring motor and sensory responses of subjects subjected to stress or drug conditions are described, along with experimental procedures. Heterophoria (as oculomotor function) and glare recovery time (time required for photochemical and neural recovery after exposure to a flash stimulus) are measured, in research aimed at developing automated objective measurement of dynamic vision functions. Onset of involuntary optokinetic nystagmus in subjects attempting to track moving stripes (while viewing through head-mounted binocular eyepieces) after exposure to glare serves as an objective measure of glare recovery time.

  8. Direct measurements of the coordination of lever arm swing and the catalytic cycle in myosin V.

    PubMed

    Trivedi, Darshan V; Muretta, Joseph M; Swenson, Anja M; Davis, Jonathon P; Thomas, David D; Yengo, Christopher M

    2015-11-24

    Myosins use a conserved structural mechanism to convert the energy from ATP hydrolysis into a large swing of the force-generating lever arm. The precise timing of the lever arm movement with respect to the steps in the actomyosin ATPase cycle has not been determined. We have developed a FRET system in myosin V that uses three donor-acceptor pairs to examine the kinetics of lever arm swing during the recovery and power stroke phases of the ATPase cycle. During the recovery stroke the lever arm swing is tightly coupled to priming the active site for ATP hydrolysis. The lever arm swing during the power stroke occurs in two steps, a fast step that occurs before phosphate release and a slow step that occurs before ADP release. Time-resolved FRET demonstrates a 20-Å change in distance between the pre- and postpower stroke states and shows that the lever arm is more dynamic in the postpower stroke state. Our results suggest myosin binding to actin in the ADP.Pi complex triggers a rapid power stroke that gates the release of phosphate, whereas a second slower power stroke may be important for mediating strain sensitivity.

  9. Coordinate interferometric system for measuring the position of a sample with infrared telecom laser diode

    NASA Astrophysics Data System (ADS)

    Holá, Miroslava; Lazar, Josef; Čížek, Martin; Hucl, Václav; Řeřucha, Šimon; Číp, Ondřej

    2016-11-01

    We report on a design of an interferometric position measuring system for control of a sample stage in an e-beam writer with reproducibility of the position on nanometer level and resolution below nanometer. We introduced differential configuration of the interferometer where the position is measured with respect to a central reference point to eliminate deformations caused by thermal and pressure effects on the vacuum chamber. The reference is here the electron gun of the writer. The interferometer is designed to operate at infrared, telecommunication wavelength due to the risk of interference of stray light with sensitive photodetectors in the chamber. The laser source is here a narrow-linewidth DFB laser diode with electronics of our own design offering precision and stability of temperature and current, low-noise, protection from rf interference, and high-frequency modulation. Detection of the interferometric signal relies on a novel derivative technique utilizing hf frequency modulation and phase-sensitive detection.

  10. A method of measuring dynamic strain under electromagnetic forming conditions.

    PubMed

    Chen, Jinling; Xi, Xuekui; Wang, Sijun; Lu, Jun; Guo, Chenglong; Wang, Wenquan; Liu, Enke; Wang, Wenhong; Liu, Lin; Wu, Guangheng

    2016-04-01

    Dynamic strain measurement is rather important for the characterization of mechanical behaviors in electromagnetic forming process, but it has been hindered by high strain rate and serious electromagnetic interference for years. In this work, a simple and effective strain measuring technique for physical and mechanical behavior studies in the electromagnetic forming process has been developed. High resolution (∼5 ppm) of strain curves of a budging aluminum tube in pulsed electromagnetic field has been successfully measured using this technique. The measured strain rate is about 10(5) s(-1), which depends on the discharging conditions, nearly one order of magnitude of higher than that under conventional split Hopkins pressure bar loading conditions (∼10(4) s(-1)). It has been found that the dynamic fracture toughness of an aluminum alloy is significantly enhanced during the electromagnetic forming, which explains why the formability is much larger under electromagnetic forging conditions in comparison with conventional forging processes.

  11. Subpicosecond measurements of polar solvation dynamics: Coumarin 153 revisited

    SciTech Connect

    Horng, M.L.; Gardecki, J.A.; Papazyan, A.; Maroncelli, M.

    1995-11-30

    Time-resolved emission measurements of the solute coumarin 153 (C153) are used to probe the time dependence of solvation in 24 common solvents at room temperature. Significant improvements in experimental time resolution ({approx}100 fs instrument response) as well as corresponding improvements in analysis methods provide confidence that all of the spectral evolution (including both the inertial and the diffusive parts of the response) are observed in these measurements. Extensive data concerning the steady-state solvatochromism of C153, coupled to an examination of the effects of vibrational relaxation, further demonstrate that the spectral dynamics being observed accurately monitor the dynamics of nonspecific solvation. Comparisons to theoretical predictions show that models based on the dielectric response of the pure solvent provide a semiquantitative understanding of the dynamics observed. 156 refs., 26 figs., 5 tabs.

  12. Emission Measure Distribution for an Active Region Using Coordinated SERTS and YOHKOH SXT Observations

    NASA Astrophysics Data System (ADS)

    Schmelz, J. T.; Saba, J. L. R.; Strong, K. T.; Winter, H. D.; Brosius, J. W.

    1999-09-01

    Often the derived temperature of an active region reflects the method and the nature of the instrument used in its measurement. The emission measure (i.e., the amount of emitting material) derived from spectroscopic observations usually depends on assumptions about the absolute elemental abundances and ionization fractions of the emitting ions. Yet establishing the distribution of emission measure with temperature is the first step needed to proceed with most of the interesting physics of active regions--including heating processes, cooling timescales, and loop stability. Accurately characterizing the thermal distribution of the coronal plasma requires data which can resolve multithermal features and constrain both low- and high-temperature emission. To model the temperature distribution of NOAA Active Region 7563, we have combined broadband filter data from the Yohkoh Soft X-Ray Telescope (SXT) with simultaneous spectral line data from the Goddard Solar EUV Rocket Telescope and Spectrograph (SERTS) taken during its flight on 1993 August 17. We have used a forward-folding technique to determine the emission measure distribution of the active region loops. We have found that (1) the SXT response functions are sensitive to both the elemental abundances and the ionization fractions assumed to compute the solar spectrum that is folded through the instrument effective area; (2) the relative calibration between the SERTS and the SXT instruments must be adjusted by a factor of 2 (a value consistent with the absolute measurement uncertainty of the 1993 SERTS flight) no matter which abundances or iron ionization fractions are used; (3) the two-peaked differential emission measure previously determined using SERTS data alone is not consistent with the SXT data: including the SXT data as a high-temperature constraint in the analysis requires that the emission above about 3 MK drop off steeply rather than extending out to 6 MK. The sensitivity of the SXT filter response

  13. The differential emission measure of dynamic coronal loops

    NASA Technical Reports Server (NTRS)

    Antiochos, S. K.

    1981-01-01

    The effects of time dependent phenomena, such as flare energization and decay, on the temperature and density structure of the transition region and, in particular, on the form of the differential emission measure are studied. It is found that unlike the case of the static models, the form of the differential emission measure can be used to determine the important physical mechanisms in the dynamic models.

  14. Quantifying the Dynamic Ocean Surface Using Underwater Radiometric Measurements

    DTIC Science & Technology

    2013-09-30

    Radiometric Measurements Dick K.P. Yue Center for Ocean Engineering Massachusetts Institute of Technology Room 5-321 77 Massachusetts Ave...comply with a collection of information if it does not display a currently valid OMB control number. 1. REPORT DATE 30 SEP 2013 2. REPORT TYPE 3. DATES ...COVERED 00-00-2013 to 00-00-2013 4. TITLE AND SUBTITLE Quantifying the Dynamic Ocean Surface Using Underwater Radiometric Measurements 5a

  15. Quantifying the Dynamic Ocean Surface Using Underwater Radiometric Measurement

    DTIC Science & Technology

    2013-09-30

    Radiometric Measurement Lian Shen Department of Mechanical Engineering & St. Anthony Falls Laboratory University of Minnesota Minneapolis, MN...information if it does not display a currently valid OMB control number. 1. REPORT DATE 30 SEP 2013 2. REPORT TYPE 3. DATES COVERED 00-00-2013 to 00-00...2013 4. TITLE AND SUBTITLE Quantifying the Dynamic Ocean Surface Using Underwater Radiometric Measurement 5a. CONTRACT NUMBER 5b. GRANT NUMBER

  16. Dynamic measurements of gear tooth friction and load

    NASA Technical Reports Server (NTRS)

    Rebbechi, Brian; Oswald, Fred B.; Townsend, Dennis P.

    1991-01-01

    As part of a program to study fundamental mechanisms of gear noise, static and dynamic gear tooth strain measurements were made on the NASA gear-noise rig. Tooth-fillet strains from low-contact ratio-spur gears were recorded for 28 operating conditions. A method is introduced whereby strain gage measurements taken from both the tension and compression sides of a gear tooth can be transformed into the normal and frictional loads on the tooth. This technique was applied to both the static and dynamic strain data. The static case results showed close agreement with expected results. For the dynamic case, the normal-force computation produced very good results, but the friction results, although promising, were not as accurate. Tooth sliding friction strongly affected the signal from the strain gage on the tensionside of the tooth. The compression gage was affected by friction to a much lesser degree. The potential of the method to measure friction force was demonstrated, but further refinement will be required before this technique can be used to measure friction forces dynamically with an acceptable degree of accuracy.

  17. Localized dynamic light scattering: a new approach to dynamic measurements in optical microscopy.

    PubMed

    Meller, A; Bar-Ziv, R; Tlusty, T; Moses, E; Stavans, J; Safran, S A

    1998-03-01

    We present a new approach to probing single-particle dynamics that uses dynamic light scattering from a localized region. By scattering a focused laser beam from a micron-size particle, we measure its spatial fluctuations via the temporal autocorrelation of the scattered intensity. We demonstrate the applicability of this approach by measuring the three-dimensional force constants of a single bead and a pair of beads trapped by laser tweezers. The scattering equations that relate the scattered intensity autocorrelation to the particle position correlation function are derived. This technique has potential applications for measurement of biomolecular force constants and probing viscoelastic properties of complex media.

  18. Dynamic Calibration and Verification Device of Measurement System for Dynamic Characteristic Coefficients of Sliding Bearing

    PubMed Central

    Chen, Runlin; Wei, Yangyang; Shi, Zhaoyang; Yuan, Xiaoyang

    2016-01-01

    The identification accuracy of dynamic characteristics coefficients is difficult to guarantee because of the errors of the measurement system itself. A novel dynamic calibration method of measurement system for dynamic characteristics coefficients is proposed in this paper to eliminate the errors of the measurement system itself. Compared with the calibration method of suspension quality, this novel calibration method is different because the verification device is a spring-mass system, which can simulate the dynamic characteristics of sliding bearing. The verification device is built, and the calibration experiment is implemented in a wide frequency range, in which the bearing stiffness is simulated by the disc springs. The experimental results show that the amplitude errors of this measurement system are small in the frequency range of 10 Hz–100 Hz, and the phase errors increase along with the increasing of frequency. It is preliminarily verified by the simulated experiment of dynamic characteristics coefficients identification in the frequency range of 10 Hz–30 Hz that the calibration data in this frequency range can support the dynamic characteristics test of sliding bearing in this frequency range well. The bearing experiments in greater frequency ranges need higher manufacturing and installation precision of calibration device. Besides, the processes of calibration experiments should be improved. PMID:27483283

  19. Dynamic Calibration and Verification Device of Measurement System for Dynamic Characteristic Coefficients of Sliding Bearing.

    PubMed

    Chen, Runlin; Wei, Yangyang; Shi, Zhaoyang; Yuan, Xiaoyang

    2016-07-30

    The identification accuracy of dynamic characteristics coefficients is difficult to guarantee because of the errors of the measurement system itself. A novel dynamic calibration method of measurement system for dynamic characteristics coefficients is proposed in this paper to eliminate the errors of the measurement system itself. Compared with the calibration method of suspension quality, this novel calibration method is different because the verification device is a spring-mass system, which can simulate the dynamic characteristics of sliding bearing. The verification device is built, and the calibration experiment is implemented in a wide frequency range, in which the bearing stiffness is simulated by the disc springs. The experimental results show that the amplitude errors of this measurement system are small in the frequency range of 10 Hz-100 Hz, and the phase errors increase along with the increasing of frequency. It is preliminarily verified by the simulated experiment of dynamic characteristics coefficients identification in the frequency range of 10 Hz-30 Hz that the calibration data in this frequency range can support the dynamic characteristics test of sliding bearing in this frequency range well. The bearing experiments in greater frequency ranges need higher manufacturing and installation precision of calibration device. Besides, the processes of calibration experiments should be improved.

  20. Coordinated ground and space measurements of auroral surge over South Pole. Technical report

    SciTech Connect

    Rosenberg, T.J.; Detrick, D.L.; Mizera, P.F.; Gorney, D.J.; Berkey, F.T.

    1988-02-01

    Coincident ground-based and satellite observations are presented of a premidnight auroral surge over Amundsen-Scott South Pole station. The set of near-simultaneous measurements provides an excellent opportunity to gain a more-quantitative understanding of the nature of premidnight substorm activity at high geomagnetic latitudes. The surge produced a rapid onset of cosmic radio noise absorption at the station. On the polar-orbiting DMSP-F6 spacecraft, intense x-ray emissions with E > 2-keV energy were imaged 1 to 2 deg magnetically equatorward of the South Pole approximately 1 min prior to the peak of the absorption event. The precipitating electron spectrum determined from the x-ray measurements could be characterized by an e-folding energy of approx. 11 keV and is found to be adequate to account for the cosmic noise absorption and maximum auroral luminosity recorded at South Pole. Photometer, all-sky camera, riometer, and magnetometer data are used to estimate the velocity of motion and spatial extent of the auroral precipitation and the ionospheric currents associated with the surge.

  1. Coordinated ground and space measurements of an auroral surge over South Pole

    SciTech Connect

    Rosenberg, T.J.; Detrick, D.L.; Mizera, P.F.; Gorney, D.J.; Berkey, F.T.; Eather, R.H.; Lanzerotti, L.J.

    1987-10-01

    Coincident ground-based and satellite observations are presented of a premidnight auroral surge over Amundsen-Scott South Pole station. The set of near-simultaneous measurements provides an excellent opportunity to gain a more quantitative understanding of the nature of premidnight substorm activity at high geomagnetic latitudes. The surge produced a rapid onset of cosmic radio noise absorption at the station. On the polar-orbiting DMSP F6 spacecraft, intense X ray emissions with E>2 keV energy were imaged 1/sup 0/ to 2/sup 0/ magnetically equatorward of South Pole approximately 1 min prior to the peak of the absorption event. The spectrum of precipitating electrons determined from the X ray measurements could be characterized by an e-folding energy of approx.11 keV and is found to be adequate to account for the cosmic noise absorption and maximum auroral luminosity recorded at South Pole. Photometer, all-sky camera, riometer, and magnetometer data are used to estimate the velocity of motion and spatial extent of the auroral precipitation and the ionospheric currents associated with the surge. The electron precipitation region is deduced to have a latitudinal scale size of <100 km and to move poleward with a speed of approx.1--2 km/s coincident with the movement of a westward electrojet.

  2. In-flight measurement of upwind dynamic soaring in albatrosses

    NASA Astrophysics Data System (ADS)

    Sachs, Gottfried

    2016-03-01

    In-flight measurement results on upwind flight of albatrosses using dynamic soaring are presented. It is shown how the birds manage to make progress against the wind on the basis of small-scale dynamic soaring maneuvers. For this purpose, trajectory features, motion quantities and mechanical energy relationships as well as force characteristics are analyzed. The movement on a large-scale basis consists of a tacking type flight technique which is composed of dynamic soaring cycle sequences with alternating orientation to the left and right. It is shown how this is performed by the birds so that they can achieve a net upwind flight without a transversal large-scale movement and how this compares with downwind or across wind flight. Results on upwind dynamic soaring are presented for low and high wind speed cases. It is quantified how much the tacking trajectory length is increased when compared with the beeline distance. The presented results which are based on in-flight measurements of free flying albatrosses were achieved with an in-house developed GPS-signal tracking method yielding the required high precision for the small-scale dynamic soaring flight maneuvers.

  3. Dynamic measurement of temperature using neutron resonance spectroscopy (NRS)

    NASA Astrophysics Data System (ADS)

    Funk, D. J.; Asay, B. W.; Bennett, B. I.; Bowman, J. D.; Boat, R. M.; Dickson, P. M.; Henson, B. F.; Hull, L. M.; Idar, D. J.; Laabs, G. W.; London, R. K.; Mace, J. L.; Morgan, G. L.; Murk, D. M.; Rabie, R. L.; Ragan, C. E.; Stacy, H. L.; Yuan, V. W.

    1998-07-01

    Accurate temperature measurements in dynamic systems have been pursued for decades and have usually relied on optical techniques. These approaches are generally hampered by insufficient information regarding the emissivity of the system under study. We are developing NRS techniques to measure temperature in dynamic systems and overcome these limitations. Many neutron resonances have narrow intrinsic Breit-Wigner widths such that the resonance is substantially broadened by the atomic motion even at room temperature. Thus, accurate measurement of the Doppler contribution allows one to infer the material temperature, and for the conditions achieved using standard high explosives, the probe itself is not perturbed by the high temperature and pressure. Experiments are conducted using a pulsed spallation source at LANSCE with time-of-flight measurement of the neutron spectra. In initial experiments, we have demonstrated that measurements with ten percent accuracy are possible. We have fielded dynamic tests, most of which were neutron-flux limited. An overview of the approach and the status of our experimental campaign are discussed.

  4. Dynamic Measurement of Temperature using Neutron Resonance Spectroscopy (NRS)

    NASA Astrophysics Data System (ADS)

    Funk, David J.; Asay, B. W.; Bennett, B. I.; Bowman, J. D.; Boat, R. M.; Henson, B. F.; Hixson, R. S.; Hull, L. M.; Laabs, G. W.; London, R. K.; Mace, J. L.; Morgan, G. L.; Murk, D. M.; Rabie, R. L.; Ragan, C. E.; Stacy, H. L.; Yuan, V. W.

    1997-07-01

    Accurate temperature measurements in dynamic systems have been pursued for decades and have usually relied on optical techniques. These approaches are generally hampered by insufficient information regarding the emissivity of the system under study. We are developing NRS techniques to measure temperature in dynamic systems and overcome these limitations. Many neutron resonances have narrow intrinsic Breit-Wigner widths such that the resonance is substantially broadened by the atomic motion even at room temperature. Thus, accurate measurement of the Doppler contribution allows one to infer the material temperature, and for the conditions achieved using standard high explosives, the probe itself is not perturbed by the high temperature and pressure. Experiments are conducted using a pulsed spallation source at LANSCE with time-of-flight measurement of the neutron spectra. In initial experiments, we have demonstrated that measurements with ten percent accuracy are possible. We have fielded dynamic tests, most of which were neutron-flux limited. An overview of the approach and the status of our experimental campaign will be discussed.

  5. Dynamically Reconfigurable Piezoelectric Sensors for Ultrasonic Nonlinearity Measurements

    NASA Astrophysics Data System (ADS)

    Kirikera, G. R.; Regez, B. A.; Balugun, O.; Zinck, A.; Krishnaswamy, S.

    2009-03-01

    Ultrasonic interaction with fatigue damage in a material can lead to nonlinear ultrasonic harmonic generation. Unfortunately, nonlinear generation is often very weak and measurement sensors need to have a large dynamic range to pick weak second harmonic signals. Furthermore, couplant dependence of the ultrasonic measurements can mask any variations in second harmonic generation due to fatigue damage. To overcome this, a couplant-independent method for ultrasonic nonlinearity measurements was recently proposed by us. This method requires two sets of transducers that can each generate/detect both the fundamental and second harmonic signals. In this paper, we describe a dynamically reconfigurable interdigitated Surface Acoustic Wave transducer mat can effectively be used to generate/receive bom the fundamental and the second harmonic signals. This is achieved using simple external electronic reconfiguration of the signals from a pair of interdigitated transducer arrays.

  6. Unitarity, feedback, interactions—dynamics emergent from repeated measurements

    NASA Astrophysics Data System (ADS)

    Altamirano, Natacha; Corona-Ugalde, Paulina; Mann, Robert B.; Zych, Magdalena

    2017-01-01

    Motivated by the recent efforts to describe the gravitational interaction as a classical channel arising from continuous quantum measurements, we study what types of dynamics can emerge from a collisional model of repeated interactions between a system and a set of ancillae. We show that contingent on the model parameters the resulting dynamics ranges from exact unitarity to arbitrarily fast decoherence (quantum Zeno effect). For a series of measurements the effective dynamics includes feedback-control, which for a composite system yields effective interactions between the subsystems. We quantify the amount of decoherence accompanying such induced interactions, generalizing the lower bound found for the gravitational example. However, by allowing multipartite measurements, we show that interactions can be induced with arbitrarily low decoherence. These results have implications for gravity-inspired decoherence models. Moreover, we show how the framework can include terms beyond the usual second-order approxiation, which can spark new quantum control or simulation protocols. Finally, within our simple approach we re-derive the quantum filtering equations for the different regimes of effective dynamics, which can facilitate new connections between different formulations of open systems.

  7. Electron energy budget in the high-latitude ionosphere during Viking/EISCAT coordinated measurements

    SciTech Connect

    Lilensten, J.; Kofman, W.; Lathuillere, C. ); Fontaine, D. ); Eliasson, L. ); Oran, E.S. )

    1990-05-01

    The magnetospheric electron fluxes precipitating at the top of the auroral ionosphere contribute to the production of ionization, to the excitation of atmospheric constituents, and to the heating of the ambient electrons. This last process occurs essentially when the energy of the initial precipitated electrons and photoelectrons has been degraded to values lower than approximately 10 eV. The heated ambient electron gas loses this energy to the neutral gas and ambient ions. Finally, the temperature gradient produced in the ionospheric plasma induces a heat flux. In the absence of an electric field and for stationary conditions, the energy budget of ionospheric electrons results from the balance between these processes of heating, cooling, and heat conduction. The intensity of these different processes is quantitatively computed at each altitude in the ionosphere by combining simultaneous EISCAT and Viking in situ measurements, and by means of an electron transport model. The stationary electron flux, which leads to the heating rate, is computed, and remaining differences in the energy budget are discussed.

  8. Pulse train fluorescence technique for measuring triplet state dynamics.

    PubMed

    De Boni, Leonardo; Franzen, Paulo L; Gonçalves, Pablo J; Borissevitch, Iouri E; Misoguti, Lino; Mendonça, Cleber R; Zilio, Sergio C

    2011-05-23

    We report on a method to study the dynamics of triplet formation based on the fluorescence signal produced by a pulse train. Basically, the pulse train acts as sequential pump-probe pulses that precisely map the excited-state dynamics in the long time scale. This allows characterizing those processes that affect the population evolution of the first excited singlet state, whose decay gives rise to the fluorescence. The technique was proven to be valuable to measure parameters of triplet formation in organic molecules. Additionally, this single beam technique has the advantages of simplicity, low noise and background-free signal detection.

  9. Measurements of nuclear spin dynamics by spin-noise spectroscopy

    SciTech Connect

    Ryzhov, I. I.; Poltavtsev, S. V.; Kozlov, G. G.; Zapasskii, V. S.; Kavokin, K. V.; Glazov, M. M.; Vladimirova, M.; Scalbert, D.; Cronenberger, S.; Lemaître, A.; Bloch, J.

    2015-06-15

    We exploit the potential of the spin noise spectroscopy (SNS) for studies of nuclear spin dynamics in n-GaAs. The SNS experiments were performed on bulk n-type GaAs layers embedded into a high-finesse microcavity at negative detuning. In our experiments, nuclear spin polarisation initially prepared by optical pumping is monitored in real time via a shift of the peak position in the electron spin noise spectrum. We demonstrate that this shift is a direct measure of the Overhauser field acting on the electron spin. The dynamics of nuclear spin is shown to be strongly dependent on the electron concentration.

  10. Multiple Point Dynamic Gas Density Measurements Using Molecular Rayleigh Scattering

    NASA Technical Reports Server (NTRS)

    Seasholtz, Richard; Panda, Jayanta

    1999-01-01

    A nonintrusive technique for measuring dynamic gas density properties is described. Molecular Rayleigh scattering is used to measure the time-history of gas density simultaneously at eight spatial locations at a 50 kHz sampling rate. The data are analyzed using the Welch method of modified periodograms to reduce measurement uncertainty. Cross-correlations, power spectral density functions, cross-spectral density functions, and coherence functions may be obtained from the data. The technique is demonstrated using low speed co-flowing jets with a heated inner jet.

  11. Multi-Agent Coordination and Cooperation in a Distributed Dynamic Environment with Limited Resources: Simulated Air Wars

    DTIC Science & Technology

    1993-11-01

    of agents [Lo, 1988; Parunak, 1987; Smith , 1980; Smith & Davis, 1981]. 2.1.2 Coordination Closely related to cooperation, coordination involves the...even compete with one another. One of the earliest, and perhaps best known, DAI coordination techniques is the contract net [Davis & Smith , 1983; Smith ...Aircraft Resources A/C Combat Factor Maximum Engagements Z=x A-toA A-to-G Enurance SedrA A-toA A-to-G F-01 5 0 3 8 3 0 F-02 10 0 4 8 3 0 F-03 15 0 5 10

  12. Enhanced crosslimb transfer of force-field learning for dynamics that are identical in extrinsic and joint-based coordinates for both limbs.

    PubMed

    Carroll, Timothy J; de Rugy, Aymar; Howard, Ian S; Ingram, James N; Wolpert, Daniel M

    2016-01-01

    Humans are able to adapt their motor commands to make accurate movements in novel sensorimotor environments, such as when wielding tools that alter limb dynamics. However, it is unclear to what extent sensorimotor representations, obtained through experience with one limb, are available to the opposite, untrained limb and in which form they are available. Here, we compared crosslimb transfer of force-field compensation after participants adapted to a velocity-dependent curl field, oriented either in the sagittal or the transverse plane. Due to the mirror symmetry of the limbs, the force field had identical effects for both limbs in joint and extrinsic coordinates in the sagittal plane but conflicting joint-based effects in the transverse plane. The degree of force-field compensation exhibited by the opposite arm in probe trials immediately after initial learning was significantly greater after sagittal (26 ± 5%) than transverse plane adaptation (9 ± 4%; P < 0.001), irrespective of whether participants learned initially with the left or the right arm or via abrupt or gradual exposure to the force field. Thus transfer was impaired when the orientation of imposed dynamics conflicted in intrinsic coordinates for the two limbs. The data reveal that neural representations of novel dynamics are only partially available to the opposite limb, since transfer is incomplete even when force-field perturbation is spatially compatible for the two limbs, according to both intrinsic and extrinsic coordinates.

  13. Enhanced crosslimb transfer of force-field learning for dynamics that are identical in extrinsic and joint-based coordinates for both limbs

    PubMed Central

    de Rugy, Aymar; Howard, Ian S.; Ingram, James N.; Wolpert, Daniel M.

    2015-01-01

    Humans are able to adapt their motor commands to make accurate movements in novel sensorimotor environments, such as when wielding tools that alter limb dynamics. However, it is unclear to what extent sensorimotor representations, obtained through experience with one limb, are available to the opposite, untrained limb and in which form they are available. Here, we compared crosslimb transfer of force-field compensation after participants adapted to a velocity-dependent curl field, oriented either in the sagittal or the transverse plane. Due to the mirror symmetry of the limbs, the force field had identical effects for both limbs in joint and extrinsic coordinates in the sagittal plane but conflicting joint-based effects in the transverse plane. The degree of force-field compensation exhibited by the opposite arm in probe trials immediately after initial learning was significantly greater after sagittal (26 ± 5%) than transverse plane adaptation (9 ± 4%; P < 0.001), irrespective of whether participants learned initially with the left or the right arm or via abrupt or gradual exposure to the force field. Thus transfer was impaired when the orientation of imposed dynamics conflicted in intrinsic coordinates for the two limbs. The data reveal that neural representations of novel dynamics are only partially available to the opposite limb, since transfer is incomplete even when force-field perturbation is spatially compatible for the two limbs, according to both intrinsic and extrinsic coordinates. PMID:26581867

  14. Optical measurements pertaining to Space Station solar dynamic power systems

    NASA Technical Reports Server (NTRS)

    Holly, S.; Springer, T.; Jefferies, K. S.

    1987-01-01

    The Space Station solar dynamic power system is a hybrid of solar photovoltaic and solar dynamic systems, the latter of which uses a parabolic reflector to collect solar energy. This paper describes analytical results of an off-axis solar illumination on the intensity distribution in arbitrary target planes perpendicular to the axis of a parabolic reflector. Such computational capability would make it possible to predict optical intensity distributions resulting from off-axis angles of incident radiation on such target planes. To validate the computer code, experimental optical measurements were performed on the multifaceted paraboloidal collecor at the Solar Dynamic Test Facility at Rockedyne's Santa Susana Field Laboratory. The experimental data compared reasonably well with the calculated values.

  15. Efficient coordination of swarms of sensor-laden balloons for persistent, in situ, real-time measurement of hurricane development*

    NASA Astrophysics Data System (ADS)

    Bewley, Thomas; Meneghello, Gianluca

    2016-10-01

    Accurate long-term forecasts of the path and intensity of severe hurricanes are imperative to protect property and save lives. Extensive real-time measurements within hurricanes, especially near their core, are essential for supplementing the limited relevant information accessible by satellites in order to improve such forecasts. Current operational methods for obtaining in situ information, such as dropsondes and repeated manned and unmanned aircraft flights over and within hurricanes, are both expensive and limited in duration. In the present work it is demonstrated by numerical experiments how a swarm of robust, inexpensive, buoyancy-controlled, sensor-laden balloons might be deployed and controlled in an energetically efficient, coordinated fashion, for days at a time, to continuously monitor relevant properties (pressure, humidity, temperature, and wind speed) of a hurricane as it develops. Rather than fighting its gale-force winds, the strong and predictable stratification of these winds is leveraged to efficiently disperse the balloons into a favorable time-evolving distribution. An iterative bootstrap approach is envisioned in which (a) sensor balloons are used to help improve the available computational estimate of the uncertain and underresolved flow field of the hurricane and (b) this (imprecise) estimate of the hurricane flow field is leveraged to improve the distribution of the sensor balloons, which then better facilitates (a), etc. The control approach envisioned in this ambitious effort is a combination of (centrally computed) model predictive control for coordination at the largest scales, which is the focus of the present paper, coupled with a feedback control strategy (decentrally computed, on the balloons themselves), for smaller-scale corrections. Our work indicates that, following such an approach, certain target orbits of interest within the hurricane can be continuously sampled by some balloons, while others make repeated sweeps between the

  16. Dynamic Measures of RSA Predict Distress and Regulation in Toddlers

    PubMed Central

    Brooker, Rebecca J.; Buss, Kristin A.

    2010-01-01

    In this study, we examined a new method for quantifying individual variability using dynamic measures of Respiratory Sinus Arrhythmia (RSA). This method incorporated temporal variation into the measurement of RSA and provided information beyond that offered by more traditional quantifications such as difference scores. Dynamic and static measures of change in RSA were tested in relation to displays of emotion and affective behaviors during a fear eliciting episode in a sample of 88 typically-developing and high-fear toddlers during a laboratory visit at age 24 months. Dynamic measures of RSA contributed information that was unique from traditionally-employed, static change scores in predicting high-fear toddlers’ displays of shyness during a fear-eliciting episode. In contrast, RSA change scores offered information related to boldness in non-high-fear children. In addition, several associations included estimates of nonlinear change in RSA. Implications for the study of individual differences in RSA and relations with emotion and emotion regulation are discussed. PMID:20373328

  17. Driven evolution of a constitutional dynamic library of molecular helices toward the selective generation of [2 x 2] gridlike arrays under the pressure of metal ion coordination.

    PubMed

    Giuseppone, Nicolas; Schmitt, Jean-Louis; Lehn, Jean-Marie

    2006-12-27

    Constitutional dynamics, self-assembly, and helical-folding control are brought together in the efficient Sc(OTf)3/microwave-catalyzed transimination of helical oligohydrazone strands, yielding highly diverse dynamic libraries of interconverting constituents through assembly, dissociation, and exchange of components. The transimination-type mechanism of the ScIII-promoted exchange, as well as its regioselectivity, occurring only at the extremities of the helical strands, allow one to perform directional terminal polymerization/depolymerization processes when starting with dissymmetric strands. A particular library is subsequently brought to express quantitatively [2 x 2] gridlike metallosupramolecular arrays in the presence of ZnII ions by component recombination generating the correct ligand from the dynamic set of interconverting strands. This behavior represents a process of driven evolution of a constitutional dynamic chemical system under the pressure (coordination interaction) of an external effector (metal ions).

  18. Dynamic analysis of sea wave data measured by LED lidar

    NASA Astrophysics Data System (ADS)

    Mori, Yasukuni; Shimada, Shohei; Shiina, Tatsuo; Baji, Hiroyuki; Takemoto, Sae

    2016-10-01

    Form of sea wave is greatly affected by not just flow and depth of sea water, but also wind blowing on the sea surface. Therefore, measurement and analysis of sea wave motion is of assistance for control and operational safety of boats and ships. Generally, oceanic information is gauged by acoustic and electric wave. But these methods have not provided enough spatial and temporal resolution, and are completely out of touch with the on-site needs. Thus, the LED liar for sea wave measurement has been developed. The dynamic analysis of sea wave image measured by the LED lidar was conducted and the relationship with wind speed was evaluated. In this report, we first present the specifications and measurement methodologies of the LED lidar. Then we describe the actual measurements of sea wave with shallow angle by using this lidar and the results of their analysis.

  19. Large-Scale Hybrid Dynamic Simulation Employing Field Measurements

    SciTech Connect

    Huang, Zhenyu; Guttromson, Ross T.; Hauer, John F.

    2004-06-30

    Simulation and measurements are two primary ways for power engineers to gain understanding of system behaviors and thus accomplish tasks in system planning and operation. Many well-developed simulation tools are available in today's market. On the other hand, large amount of measured data can be obtained from traditional SCADA systems and currently fast growing phasor networks. However, simulation and measurement are still two separate worlds. There is a need to combine the advantages of simulation and measurements. In view of this, this paper proposes the concept of hybrid dynamic simulation which opens up traditional simulation by providing entries for measurements. A method is presented to implement hybrid simulation with PSLF/PSDS. Test studies show the validity of the proposed hybrid simulation method. Applications of such hybrid simulation include system event playback, model validation, and software validation.

  20. A Dynamic Attitude Measurement System Based on LINS

    PubMed Central

    Li, Hanzhou; Pan, Quan; Wang, Xiaoxu; Zhang, Juanni; Li, Jiang; Jiang, Xiangjun

    2014-01-01

    A dynamic attitude measurement system (DAMS) is developed based on a laser inertial navigation system (LINS). Three factors of the dynamic attitude measurement error using LINS are analyzed: dynamic error, time synchronization and phase lag. An optimal coning errors compensation algorithm is used to reduce coning errors, and two-axis wobbling verification experiments are presented in the paper. The tests indicate that the attitude accuracy is improved 2-fold by the algorithm. In order to decrease coning errors further, the attitude updating frequency is improved from 200 Hz to 2000 Hz. At the same time, a novel finite impulse response (FIR) filter with three notches is designed to filter the dither frequency of the ring laser gyro (RLG). The comparison tests suggest that the new filter is five times more effective than the old one. The paper indicates that phase-frequency characteristics of FIR filter and first-order holder of navigation computer constitute the main sources of phase lag in LINS. A formula to calculate the LINS attitude phase lag is introduced in the paper. The expressions of dynamic attitude errors induced by phase lag are derived. The paper proposes a novel synchronization mechanism that is able to simultaneously solve the problems of dynamic test synchronization and phase compensation. A single-axis turntable and a laser interferometer are applied to verify the synchronization mechanism. The experiments results show that the theoretically calculated values of phase lag and attitude error induced by phase lag can both match perfectly with testing data. The block diagram of DAMS and physical photos are presented in the paper. The final experiments demonstrate that the real-time attitude measurement accuracy of DAMS can reach up to 20″ (1σ) and the synchronization error is less than 0.2 ms on the condition of three axes wobbling for 10 min. PMID:25177802

  1. Dynamic viscosity measurement in non-Newtonian graphite nanofluids.

    PubMed

    Duan, Fei; Wong, Ting Foong; Crivoi, Alexandru

    2012-07-02

    : The effective dynamic viscosity was measured in the graphite water-based nanofluids. The shear thinning non-Newtonian behavior is observed in the measurement. On the basis of the best fitting of the experimental data, the viscosity at zero shear rate or at infinite shear rate is determined for each of the fluids. It is found that increases of the particle volume concentration and the holding time period of the nanofluids result in an enhancement of the effective dynamic viscosity. The maximum enhancement of the effective dynamic viscosity at infinite rate of shear is more than 24 times in the nanofluids held for 3 days with the volume concentration of 4% in comparison with the base fluid. A transmission electron microscope is applied to reveal the morphology of aggregated nanoparticles qualitatively. The large and irregular aggregation of the particles is found in the 3-day fluids in the drying samples. The Raman spectra are extended to characterize the D and G peaks of the graphite structure in the nanofluids. The increasing intensity of the D peak indicates the nanoparticle aggregation growing with the higher concentration and the longer holding time of the nanofluids. The experimental results suggest that the increase on effective dynamic viscosity of nanofluids is related to the graphite nanoparticle aggregation in the fluids.

  2. Investigating dynamical complexity of geomagnetic jerks using various entropy measures

    NASA Astrophysics Data System (ADS)

    Balasis, Georgios; Potirakis, Stelios; Mandea, Mioara

    2016-06-01

    Recently, many novel concepts originated in dynamical systems or information theory have been developed, partly motivated by specific research questions linked to geosciences, and found a variety of different applications. This continuously extending toolbox of nonlinear time series analysis highlights the importance of the dynamical complexity to understand the behavior of the complex Earth's system and its components. Here, we propose to apply such new approaches, mainly a series of entropy methods to the time series of the geomagnetic field. Two datasets provided by Chambon la Foret (France) and Niemegk (Germany) observatories are considered for analysis to detect dynamical complexity changes associated with geomagnetic jerks, the abrupt changes in the second temporal derivative of the Earth's magnetic field. The results clearly demonstrate the ability of Shannon and Tsallis entropies as well as Fisher information to detect events in a regional manner having identified complexities lower than the background in time intervals when geomagnetic jerks have already been reported in the literature. Additionally, these information measures are directly applicable to the original data without having to derive the secular variation or acceleration from the observatory monthly means. The strength of the proposed analysis to reveal dynamical complexity features associated with geomagnetic jerks can be utilized for analyzing not only ground measurements, but also satellite data, as those provided by the current magnetic field mission of Swarm.

  3. Plasma crystal dynamics measured with a three-dimensional plenoptic camera.

    PubMed

    Jambor, M; Nosenko, V; Zhdanov, S K; Thomas, H M

    2016-03-01

    Three-dimensional (3D) imaging of a single-layer plasma crystal was performed using a commercial plenoptic camera. To enhance the out-of-plane oscillations of particles in the crystal, the mode-coupling instability (MCI) was triggered in it by lowering the discharge power below a threshold. 3D coordinates of all particles in the crystal were extracted from the recorded videos. All three fundamental wave modes of the plasma crystal were calculated from these data. In the out-of-plane spectrum, only the MCI-induced hot spots (corresponding to the unstable hybrid mode) were resolved. The results are in agreement with theory and show that plenoptic cameras can be used to measure the 3D dynamics of plasma crystals.

  4. Evaluation of the sensing block method for dynamic force measurement

    NASA Astrophysics Data System (ADS)

    Zhang, Qinghui; Chen, Hao; Li, Wenzhao; Song, Li

    2017-01-01

    Sensing block method was proposed for the dynamic force measurement by Tanimura et al. in 1994. Comparing with the Split Hopkinson pressure bar (SHPB) technique, it can provide a much longer measuring time for the dynamic properties test of materials. However, the signals recorded by sensing block are always accompanied with additional oscillations. Tanimura et al. discussed the effect of force rising edge on the test results, whereas more research is still needed. In this paper, some more dominant factors have been extracted through dimensional analysis. The finite element simulation has been performed to assess these factors. Base on the analysis and simulation, some valuable results are obtained and some criterions proposed in this paper can be applied in design or selection of the sensing block.

  5. Measuring Predictability of Autonomous Network Transitions into Bursting Dynamics

    PubMed Central

    Mofakham, Sima; Zochowski, Michal

    2015-01-01

    Understanding spontaneous transitions between dynamical modes in a network is of significant importance. These transitions may separate pathological and normal functions of the brain. In this paper, we develop a set of measures that, based on spatio-temporal features of network activity, predict autonomous network transitions from asynchronous to synchronous dynamics under various conditions. These metrics quantify spike-timing distributions within a narrow time window as a function of the relative location of the active neurons. We applied these metrics to investigate the properties of these transitions in excitatory-only and excitatory-and-inhibitory networks and elucidate how network topology, noise level, and cellular heterogeneity affect both the reliability and the timeliness of the predictions. The developed measures can be calculated in real time and therefore potentially applied in clinical situations. PMID:25855975

  6. Measuring predictability of autonomous network transitions into bursting dynamics.

    PubMed

    Mofakham, Sima; Zochowski, Michal

    2015-01-01

    Understanding spontaneous transitions between dynamical modes in a network is of significant importance. These transitions may separate pathological and normal functions of the brain. In this paper, we develop a set of measures that, based on spatio-temporal features of network activity, predict autonomous network transitions from asynchronous to synchronous dynamics under various conditions. These metrics quantify spike-timing distributions within a narrow time window as a function of the relative location of the active neurons. We applied these metrics to investigate the properties of these transitions in excitatory-only and excitatory-and-inhibitory networks and elucidate how network topology, noise level, and cellular heterogeneity affect both the reliability and the timeliness of the predictions. The developed measures can be calculated in real time and therefore potentially applied in clinical situations.

  7. Laser Velocimetry Measurements of Oscillating Airfoil Dynamic Stall Flow Field

    DTIC Science & Technology

    1991-06-01

    Velocimetry Measurements of Oscillating Airfoil Dynamic Stall Flow Field By M.S.Chandrasekharal Navy-NASA Joint Institute of Aeronautics and Fluid Mechanics ...tunnel of the Fluid Mechanics Laboratory(FML) angle information. The other could be used for the at NASA Ames Research Center (ARC). It is one of...were on throat is always kept choked so that no disturbances a different traverse mechanism , but this was driven as can propagate upstream into the

  8. Measuring contemporary crustal motions; NASA’s Crustal Dynamics Project

    USGS Publications Warehouse

    Frey, H. V.; Bosworth, J. M.

    1988-01-01

    In this article we describe briefly the two space geodetic techniques and how they are used by the Crustal Dynamics Project, show some of the very exciting results that have emerged at the halfway point in the project's life, describe the availability and utilization of the data being collected, and consider what the future may hold when measurement accuracies eventually exceed even those now available and when other international groups become more heavily involved.   

  9. Quantifying the Dynamic Ocean Surface Using Underwater Radiometric Measurements

    DTIC Science & Technology

    2015-03-31

    2. REPORT DATE 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER 6. AUTHOR(S) 7. PERFORMING ORGANIZATION NAME(S) AND...WORK UNIT NUMBER 1. REPORT DATE (DD-MM-YYYY) 16. SECURITY CLASSIFICATION OF: PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 31-03-2015...Final March 2013 -- February 2015 Quantifying the Dynamic Ocean Surface Using Underwater Radiometric Measurements N00014-13-1-0352 Yue, Dick K.P

  10. Dynamic CT perfusion measurement in a cardiac phantom.

    PubMed

    Ziemer, Benjamin P; Hubbard, Logan; Lipinski, Jerry; Molloi, Sabee

    2015-10-01

    Widespread clinical implementation of dynamic CT myocardial perfusion has been hampered by its limited accuracy and high radiation dose. The purpose of this study was to evaluate the accuracy and radiation dose reduction of a dynamic CT myocardial perfusion technique based on first pass analysis (FPA). To test the FPA technique, a pulsatile pump was used to generate known perfusion rates in a range of 0.96-2.49 mL/min/g. All the known perfusion rates were determined using an ultrasonic flow probe and the known mass of the perfusion volume. FPA and maximum slope model (MSM) perfusion rates were measured using volume scans acquired from a 320-slice CT scanner, and then compared to the known perfusion rates. The measured perfusion using FPA (P(FPA)), with two volume scans, and the maximum slope model (P(MSM)) were related to known perfusion (P(K)) by P(FPA) = 0.91P(K) + 0.06 (r = 0.98) and P(MSM) = 0.25P(K) - 0.02 (r = 0.96), respectively. The standard error of estimate for the FPA technique, using two volume scans, and the MSM was 0.14 and 0.30 mL/min/g, respectively. The estimated radiation dose required for the FPA technique with two volume scans and the MSM was 2.6 and 11.7-17.5 mSv, respectively. Therefore, the FPA technique can yield accurate perfusion measurements using as few as two volume scans, corresponding to approximately a factor of four reductions in radiation dose as compared with the currently available MSM. In conclusion, the results of the study indicate that the FPA technique can make accurate dynamic CT perfusion measurements over a range of clinically relevant perfusion rates, while substantially reducing radiation dose, as compared to currently available dynamic CT perfusion techniques.

  11. Generalized Dynamic Factor Models for Mixed-Measurement Time Series

    PubMed Central

    Cui, Kai; Dunson, David B.

    2013-01-01

    In this article, we propose generalized Bayesian dynamic factor models for jointly modeling mixed-measurement time series. The framework allows mixed-scale measurements associated with each time series, with different measurements having different distributions in the exponential family conditionally on time-varying latent factor(s). Efficient Bayesian computational algorithms are developed for posterior inference on both the latent factors and model parameters, based on a Metropolis Hastings algorithm with adaptive proposals. The algorithm relies on a Greedy Density Kernel Approximation (GDKA) and parameter expansion with latent factor normalization. We tested the framework and algorithms in simulated studies and applied them to the analysis of intertwined credit and recovery risk for Moody’s rated firms from 1982–2008, illustrating the importance of jointly modeling mixed-measurement time series. The article has supplemental materials available online. PMID:24791133

  12. Generalized Dynamic Factor Models for Mixed-Measurement Time Series.

    PubMed

    Cui, Kai; Dunson, David B

    2014-02-12

    In this article, we propose generalized Bayesian dynamic factor models for jointly modeling mixed-measurement time series. The framework allows mixed-scale measurements associated with each time series, with different measurements having different distributions in the exponential family conditionally on time-varying latent factor(s). Efficient Bayesian computational algorithms are developed for posterior inference on both the latent factors and model parameters, based on a Metropolis Hastings algorithm with adaptive proposals. The algorithm relies on a Greedy Density Kernel Approximation (GDKA) and parameter expansion with latent factor normalization. We tested the framework and algorithms in simulated studies and applied them to the analysis of intertwined credit and recovery risk for Moody's rated firms from 1982-2008, illustrating the importance of jointly modeling mixed-measurement time series. The article has supplemental materials available online.

  13. Investigating dynamical complexity in the magnetosphere using various entropy measures

    NASA Astrophysics Data System (ADS)

    Balasis, Georgios; Daglis, Ioannis A.; Papadimitriou, Constantinos; Kalimeri, Maria; Anastasiadis, Anastasios; Eftaxias, Konstantinos

    2009-09-01

    The complex system of the Earth's magnetosphere corresponds to an open spatially extended nonequilibrium (input-output) dynamical system. The nonextensive Tsallis entropy has been recently introduced as an appropriate information measure to investigate dynamical complexity in the magnetosphere. The method has been employed for analyzing Dst time series and gave promising results, detecting the complexity dissimilarity among different physiological and pathological magnetospheric states (i.e., prestorm activity and intense magnetic storms, respectively). This paper explores the applicability and effectiveness of a variety of computable entropy measures (e.g., block entropy, Kolmogorov entropy, T complexity, and approximate entropy) to the investigation of dynamical complexity in the magnetosphere. We show that as the magnetic storm approaches there is clear evidence of significant lower complexity in the magnetosphere. The observed higher degree of organization of the system agrees with that inferred previously, from an independent linear fractal spectral analysis based on wavelet transforms. This convergence between nonlinear and linear analyses provides a more reliable detection of the transition from the quiet time to the storm time magnetosphere, thus showing evidence that the occurrence of an intense magnetic storm is imminent. More precisely, we claim that our results suggest an important principle: significant complexity decrease and accession of persistency in Dst time series can be confirmed as the magnetic storm approaches, which can be used as diagnostic tools for the magnetospheric injury (global instability). Overall, approximate entropy and Tsallis entropy yield superior results for detecting dynamical complexity changes in the magnetosphere in comparison to the other entropy measures presented herein. Ultimately, the analysis tools developed in the course of this study for the treatment of Dst index can provide convenience for space weather

  14. Six degree of freedom optical sensor for dynamic measurement of linear axes

    NASA Astrophysics Data System (ADS)

    Kroll, Jeremy John

    In an effort to reduce the error characterization time of linear axes, a six degree of freedom optical sensor has been developed. The sensor consists of a fixed source and a small moving target. The sensor uses a 5 kHz sample rate to allow dynamic, simultaneous measurement of all six degrees of freedom. The moving element is purely optical, scales with beam size and can easily be reduced in size to a 25 mm cube that weighs approximately 50 grams. Using a stabilized helium-neon laser source, the current system has a linear displacement resolution of 153 nm. The straightness resolution, with 0.4 meters between the source and the lateral effect photodiode, is 250 nm. This corresponds to a resolution for pitch and yaw of 1.25 muradians. With the current available laser input power, the theoretical resolution of the roll measurement is 2 muradians. The majority of machine tools and coordinate measuring machines used today consist of stacked linear axes. In order to obtain three dimensional controlled motion, machines typically have three nominally linear axes. To increase the accuracy of these machines, high accuracy characterization tools, such as the one developed in this research, are used to measure errors along the axes of motion. These measured errors are then used to compensate the motion of the machine.

  15. The application of co-ordination dynamics to the analysis of discrete movements using table-tennis as a paradigm skill.

    PubMed

    Sørensen, V; Ingvaldsen, R P; Whiting, H T

    2001-07-01

    The purpose of this experiment was to explore the application of co-ordination dynamics to the analysis of discrete rather than cyclical movements. Subjects, standing in a fixed position, were required to return table-tennis balls delivered to different spatial locations in the direction of a fixed target. This was achieved in condition 1 by systematically scaling, from left to right and vice versa, the 'spatial location' of the ball-identified as a control parameter. In condition 2, the control condition, the spatial location was varied randomly over the same range. The changes between regimes of the stroke co-ordination pattern, defined at two different levels, (1) organisational--forehand or backhand drive. and (2) kinematic-the distance of the bat at ball-bat contact relative to the leading edge of the table, were identified as collective variables, the values of which changed spontaneously at the transition points exposed by the control parameter. The switch between regimes was shown to be dependent upon the direction of scaling, i.e. a hysteresis effect was identified in both conditions. These findings confirm that the conceptual and methodological frameworks of co-ordination dynamics can be applied, appropriately, to the analysis of discrete movements. Moreover, it would seem that control parameter values (spatial location of the ball) do not necessarily have to be scaled in a systematic way in order to produce the required effects.

  16. Retrieval of Surface Emissivity in a Venus Coordinate Patch as Parameter Common to Repeated Measurements by VIRTIS/VEX

    NASA Astrophysics Data System (ADS)

    Kappel, D.; Arnold, G.; Haus, R.

    2012-04-01

    . By treating surface emissivity at a certain surface coordinate bin as parameter common to repeated measurements covering this bin, the retrieval uncertainty can be greatly decreased in comparison to isolated retrievals from individual measurements. When several bins that sample a patch on the surface are analyzed at once, a local surface emissivity map can be determined. This map thus results from rigorous radiative transfer and retrieval, where each single measurement is parameterized by a consistent set of atmospheric, surface, and instrumental parameters. The combined parameter set of all analyzed measurements respects all available a priori data and the measurement/simulation error distributions and does not neglect the context between adjacent measurements. The declaration of surface emissivity as a parameter common to certain measurements from the outset represents an approach that is more rigorous as compared to a simple averaging of individual retrievals which implicitly allows inconsistent parameter sets. The results for a selected surface area in the vicinity of Idunn Mons are discussed exemplarily.

  17. An Improved Method for Dynamic Measurement of Deflections of the Vertical Based on the Maintenance of Attitude Reference

    PubMed Central

    Dai, Dongkai; Wang, Xingshu; Zhan, Dejun; Huang, Zongsheng

    2014-01-01

    A new method for dynamic measurement of deflections of the vertical (DOV) is proposed in this paper. The integration of an inertial navigation system (INS) and global navigation satellite system (GNSS) is constructed to measure the body's attitude with respect to the astronomical coordinates. Simultaneously, the attitude with respect to the geodetic coordinates is initially measured by a star sensor under quasi-static condition and then maintained by the laser gyroscope unit (LGU), which is composed of three gyroscopes in the INS, when the vehicle travels along survey lines. Deflections of the vertical are calculated by using the difference between the attitudes with respect to the geodetic coordinates and astronomical coordinates. Moreover, an algorithm for removing the trend error of the vertical deflections is developed with the aid of Earth Gravitational Model 2008 (EGM2008). In comparison with traditional methods, the new method required less accurate GNSS, because the dynamic acceleration calculation is avoided. The errors of inertial sensors are well resolved in the INS/GNSS integration, which is implemented by a Rauch–Tung–Striebel (RTS) smoother. In addition, a single-axis indexed INS is adopted to improve the observability of the system errors and to restrain the inertial sensor errors. The proposed method is validated by Monte Carlo simulations. The results show that deflections of the vertical can achieve a precision of better than 1″ for a single survey line. The proposed method can be applied to a gravimetry system based on a ground vehicle or ship with a speed lower than 25 m/s. PMID:25192311

  18. Lidar Measurements of Atmospheric Dynamics over High Mountainous Terrain

    NASA Astrophysics Data System (ADS)

    Peshev, Zahary Y.; Deleva, Atanaska D.; Dreischuh, Tanja N.; Stoyanov, Dimitar V.

    2010-01-01

    Results of lidar observations on the dynamics of atmospheric layers over the ridge and northeast slope of Vitosha Mountain situated close to Sofia, Bulgaria, are reported and compared with results for layers over surrounding plain and urban zones. Measurements are carried out at 1064 nm wavelength with a lidar range resolution of 15 m, by using one of the aerosol channels of a combined Raman-aerosol lidar based on a powerful Nd:YAG laser. Two cases of distinctly different weather conditions are studied. The mountainous area, situated from 6 km to 12 km away from the lidar station, is scanned reiteratively within 7°-9° slope-angle range. Multiple series of lidar profiles are registered with average time of 2-5 s. Lidar signals are then range corrected and processed statistically. Normalized standard deviation is used as a characteristic of the atmospheric dynamics. The spatial-temporal evolution of atmospheric density fluctuations is shown on colormap plots. Intensive air dynamics over the mountain is revealed, exceeding considerably the one over the plain zone. Peculiarities of the dynamics in the investigated atmospheric domains are discussed. Results obtained show that Vitosha Mountain strongly affects variations of the atmospheric density and stability over large areas.

  19. Behavioral Dynamics in Swimming: The Appropriate Use of Inertial Measurement Units

    PubMed Central

    Guignard, Brice; Rouard, Annie; Chollet, Didier; Seifert, Ludovic

    2017-01-01

    Motor control in swimming can be analyzed using low- and high-order parameters of behavior. Low-order parameters generally refer to the superficial aspects of movement (i.e., position, velocity, acceleration), whereas high-order parameters capture the dynamics of movement coordination. To assess human aquatic behavior, both types have usually been investigated with multi-camera systems, as they offer high three-dimensional spatial accuracy. Research in ecological dynamics has shown that movement system variability can be viewed as a functional property of skilled performers, helping them adapt their movements to the surrounding constraints. Yet to determine the variability of swimming behavior, a large number of stroke cycles (i.e., inter-cyclic variability) has to be analyzed, which is impossible with camera-based systems as they simply record behaviors over restricted volumes of water. Inertial measurement units (IMUs) were designed to explore the parameters and variability of coordination dynamics. These light, transportable and easy-to-use devices offer new perspectives for swimming research because they can record low- to high-order behavioral parameters over long periods. We first review how the low-order behavioral parameters (i.e., speed, stroke length, stroke rate) of human aquatic locomotion and their variability can be assessed using IMUs. We then review the way high-order parameters are assessed and the adaptive role of movement and coordination variability in swimming. We give special focus to the circumstances in which determining the variability between stroke cycles provides insight into how behavior oscillates between stable and flexible states to functionally respond to environmental and task constraints. The last section of the review is dedicated to practical recommendations for coaches on using IMUs to monitor swimming performance. We therefore highlight the need for rigor in dealing with these sensors appropriately in water. We explain the

  20. Hydro-resistive measurement of dynamic lifting strength.

    PubMed

    Pinder, A D; Grieve, D W

    1997-04-01

    A device is described for measuring strength and power outputs of dynamic vertical lifts between heights of 0.4 and 2.2 m. The device is safe, robust, and easily transportable. It consists of a water-filled tube 2 m high and 200 mm internal diameter. The subject pulls vertically on a handle which is connected with flexible wire rope via a series of pulleys to a piston suspended inside the tube. The piston has holes which can be closed with bungs. The drag force is proportional to the square of the velocity. The constant of proportionality can be chosen over a more than 100-fold range and is independent of temperature. Manual force is measured using a strain gauged cantilever over which the rope passes. Rope movement is monitored with a shaft encoder. These devices are sampled synchronously by an interfaced computer. Velocity and power are derived from the measurements of displacement, time and force. The device is highly accurate. Power measurements are not significantly different on two separate days although repetitions on one day show a warming-up effect. This device allows the study of dynamic lifts ranging from slow, high force, quasi-isokinetic lifts to lifts where high velocities and accelerations occur.

  1. Measurements of radiated elastic wave energy from dynamic tensile cracks

    NASA Technical Reports Server (NTRS)

    Boler, Frances M.

    1990-01-01

    The role of fracture-velocity, microstructure, and fracture-energy barriers in elastic wave radiation during a dynamic fracture was investigated in experiments in which dynamic tensile cracks of two fracture cofigurations of double cantilever beam geometry were propagating in glass samples. The first, referred to as primary fracture, consisted of fractures of intact glass specimens; the second configuration, referred to as secondary fracture, consisted of a refracture of primary fracture specimens which were rebonded with an intermittent pattern of adhesive to produce variations in fracture surface energy along the crack path. For primary fracture cases, measurable elastic waves were generated in 31 percent of the 16 fracture events observed; the condition for radiation of measurable waves appears to be a local abrupt change in the fracture path direction, such as occurs when the fracture intersects a surface flaw. For secondary fractures, 100 percent of events showed measurable elastic waves; in these fractures, the ratio of radiated elastic wave energy in the measured component to fracture surface energy was 10 times greater than for primary fracture.

  2. Measuring methods for evaluation of dynamic tyre properties

    NASA Astrophysics Data System (ADS)

    Kmoch, Klaus

    1992-01-01

    Extensive measuring methods for macroscopic assessment of tire properties, based on classical mechanics and dynamics, are presented. Theoretical results and measurements were included in an expert system, where the pneumatic tire is represented as a wheel with particular elastic properties. For geometry measurement of the tire surface, a laser scanner test bed was used. The tire was excited with a shaker in order to obtain acceleration signals and for estimating global parameters such as stiffness, damping, and nonlinearity influence, which is found to increase with excitation force. Tire dynamic behavior was examined by low velocities with microscopy and infrared thermography, in order to quantify temperature augmentation and tangential and normal forces in the contact area; the slip stick oscillations were recorded on microphones. A drum test bed was used for studying tire behavior at high velocities and the tire vehicle interaction was established with acceleration measurements; nonuniformity influence on rolling stability was ascertained. The results were compared with data from theoretical models, which are pinpoint mass systems or multiple bodies problems.

  3. Novel dynamic measures of emetic behavior in musk shrews

    PubMed Central

    Horn, Charles C.; Wang, Hong; Estival, Laureline; Meyers, Kelly; Magnusson, Magnus

    2013-01-01

    The emetic reflex occurs as a pattern of motor responses produced by a network of neurons in the hindbrain. Despite an understanding of the sequence of motor outputs that form an emetic episode (EE), the variability in the dynamics of multiple EEs across time remains a mystery. Nearly all clinical studies rely on once a day patient recall of total amount of vomiting, and preclinical studies frequently report only the total number of EE per unit time. The aim of the current study was to develop novel temporal measures of emetic activation in a preclinical model. Male and female musk shrews were tested with prototypical emetic stimuli: motion exposure (1 Hz), nicotine (5 mg/kg, sc), and copper sulfate (120 mg/kg, ig). New emetic measures included duration (time from first to last episode), rate, standard deviation of the inter-episode interval (SD-I), and a survival analysis of emetic latency (analyzed with Cox regression). Behavioral patterns associated with emesis were also assessed using statistical temporal pattern (T-pattern) analysis to measure nausea-like behaviors (e.g., immobility). The emetic stimuli produced different levels of total EE number, duration, rate, and SD-I. A typical antiemetic, the neurokinin 1 receptor antagonist CP-99,994, suppressed the number of EEs but was less effective for reducing the duration or prolonging the emetic latency. Overall, the current study shows the use of novel dynamic behavioral measures to more comprehensively assess emesis and the impact of therapies. PMID:23953843

  4. Measurement of dynamic task related functional networks using MEG.

    PubMed

    O'Neill, George C; Tewarie, Prejaas K; Colclough, Giles L; Gascoyne, Lauren E; Hunt, Benjamin A E; Morris, Peter G; Woolrich, Mark W; Brookes, Matthew J

    2017-02-01

    The characterisation of dynamic electrophysiological brain networks, which form and dissolve in order to support ongoing cognitive function, is one of the most important goals in neuroscience. Here, we introduce a method for measuring such networks in the human brain using magnetoencephalography (MEG). Previous network analyses look for brain regions that share a common temporal profile of activity. Here distinctly, we exploit the high spatio-temporal resolution of MEG to measure the temporal evolution of connectivity between pairs of parcellated brain regions. We then use an ICA based procedure to identify networks of connections whose temporal dynamics covary. We validate our method using MEG data recorded during a finger movement task, identifying a transient network of connections linking somatosensory and primary motor regions, which modulates during the task. Next, we use our method to image the networks which support cognition during a Sternberg working memory task. We generate a novel neuroscientific picture of cognitive processing, showing the formation and dissolution of multiple networks which relate to semantic processing, pattern recognition and language as well as vision and movement. Our method tracks the dynamics of functional connectivity in the brain on a timescale commensurate to the task they are undertaking.

  5. Measurements of granular flow dynamics with high speed digital images

    SciTech Connect

    Lee, J.

    1994-12-31

    The flow of granular materials is common to many industrial processes. This dissertation suggests and validates image processing algorithms applied to high speed digital images to measure the dynamics (velocity, temperature and volume fraction) of dry granular solids flowing down an inclined chute under the action of gravity. Glass and acrylic particles have been used as granular solids in the experiment. One technique utilizes block matching for spatially averaged velocity measurements of the glass particles. This technique is compared with the velocity measurement using an optic probe which is a conventional granular flow velocity measurement device. The other technique for measuring the velocities of individual acrylic particles is developed with correspondence using a Hopfield network. This technique first locates the positions of particles with pattern recognition techniques, followed by a clustering technique, which produces point patterns. Also, several techniques are compared for particle recognition: synthetic discriminant function (SDF), minimum average correlation energy (MACE) filter, modified minimum average correlation energy (MMACE) filter and variance normalized correlation. The author proposes an MMACE filter which improves generalization of the MACE filter by adjusting the amount of averaged spectrum of training images in the spectrum whitening stages of the MACE filter. Variance normalized correlation is applied to measure the velocity and temperature of flowing glass particles down the inclined chute. The measurements are taken for the steady and wavy flow and qualitatively compared with a theoretical model of granular flow.

  6. A three-coordinate system (ecliptic, galactic, ISMF) spectral analysis of heliospheric ENA emissions using CASSINI/INCA measurements

    SciTech Connect

    Dialynas, K.; Krimigis, S. M.; Mitchell, D. G.; Roelof, E. C.; Decker, R. B

    2013-11-20

    In the present study, we use all-sky energy-resolved energetic neutral atom (ENA) maps obtained by the Ion and Neutral CAmera (INCA) instrument on board Cassini that correspond to the time period from 2003 to 2009, in four discrete energy passbands (∼5.4 to ∼55 keV), to investigate the geometrical characteristics of the belt (a broad band of emission in the sky). The heliospheric ENA emissions are mapped in three different coordinate systems (ecliptic, Galactic, and interstellar magnetic field (ISMF)), and spectral analyses are performed to further examine the belt's possible energy dependence. Our conclusions are summarized as follows: (1) the high flux ENA belt identified in the energy range of 8-42 keV is moderately well organized in Galactic coordinates, as the ENA minima appear in the vicinity of the north and south Galactic poles; (2) using minimization criteria ( B · R ∼ 0), the deviation of the ENA emissions from the equator is effectively minimized in a rotated frame, which we interpret as ISMF, where its north pole points toward 190° ecliptic longitude and 15° ecliptic latitude; (3) ENA spectra show a power-law form in energy that can be fitted with a single function presenting higher spectral slopes in the belt region and lower outside (3.4 < γ < 4.4); (4) the spectra are almost indistinguishable between the tail and the nose regions, i.e., no noticeable asymmetry is observed; (5) the consistency of the ENA distributions as a function of latitude among the different INCA channels indicates that the morphology of the belt (peak, width, and structure) is nearly energy independent from 8 keV to 30 keV (minor deviations start to appear at >35 keV); and (6) in the low count rate regions, the long-term ENA count rate profiles do not match the measured cosmic ray profiles, indicating that even the minimum ENA emissions detected by INCA are foreground ENAs.

  7. The Neural Network In Coordinate Transformation

    NASA Astrophysics Data System (ADS)

    Urusan, Ahmet Yucel

    2011-12-01

    In international literature, Coordinate operations is divided into two categories. They are coordinate conversion and coordinate transformation. Coordinates converted from coordinate system A to coordinate system B in the same datum (mean origine, scale and axis directions are same) by coordinate conversion. There are two different datum in coordinate transformation. The basis of each datum to a different coordinate reference system. In Coordinate transformation, coordinates are transformed from coordinate reference system A to coordinate referance system B. Geodetic studies based on physical measurements. Coordinate transformation needs identical points which were measured in each coordinate reference system (A and B). However it is difficult (and need a big reserved budget) to measure in some places like as top of mountain, boundry of countries and seaside. In this study, this sample problem solution was researched. The method of learning which is one of the neural network methods, was used for solution of this problem.

  8. Beyond the blank slate: routes to learning new coordination patterns depend on the intrinsic dynamics of the learner-experimental evidence and theoretical model.

    PubMed

    Kostrubiec, Viviane; Zanone, Pier-Giorgio; Fuchs, Armin; Kelso, J A Scott

    2012-01-01

    Using an approach that combines experimental studies of bimanual movements to visual stimuli and theoretical modeling, the present paper develops a dynamical account of sensorimotor learning, that is, how new skills are acquired and old ones modified. A significant aspect of our approach is the focus on the individual learner as the basic unit of analysis, in particular the quantification of predispositions and capabilities that the individual learner brings to the learning environment. Such predispositions constitute the learner's behavioral repertoire, captured here theoretically as a dynamical landscape ("intrinsic dynamics"). The learning process is demonstrated to not only lead to a relatively permanent improvement of performance in the required task-the usual outcome-but also to alter the individual's entire repertoire. Changes in the dynamical landscape due to learning are shown to result from two basic mechanisms or "routes": bifurcation and shift. Which mechanism is selected depends the initial individual repertoire before new learning begins. Both bifurcation and shift mechanisms are accommodated by a dynamical model, a relatively straightforward development of the well-established HKB model of movement coordination. Model simulations show that although environmental or task demands may be met equally well using either mechanism, the bifurcation route results in greater stabilization of the to-be-learned behavior. Thus, stability not (or not only) error is demonstrated to be the basis of selection, both of a new pattern of behavior and the path (smooth shift versus abrupt qualitative change) that learning takes. In line with these results, recent neurophysiological evidence indicates that stability is a relevant feature around which brain activity is organized while an individual performs a coordination task. Finally, we explore the consequences of the dynamical approach to learning for theories of biological change.

  9. High spatial resolution measurements of ram accelerator gas dynamic phenomena

    NASA Technical Reports Server (NTRS)

    Hinkey, J. B.; Burnham, E. A.; Bruckner, A. P.

    1992-01-01

    High spatial resolution experimental tube wall pressure measurements of ram accelerator gas dynamic phenomena are presented. The projectile resembles the centerbody of a ramjet and travels supersonically through a tube filled with a combustible gaseous mixture, with the tube acting as the outer cowling. Pressure data are recorded as the projectile passes by sensors mounted in the tube wall at various locations along the tube. Data obtained by using a special highly instrumented section of tube has allowed the recording of gas dynamic phenomena with a spatial resolution on the order of one tenth the projectile length. High spatial resolution tube wall pressure data from the three regimes of propulsion studied to date (subdetonative, transdetonative, and superdetonative) are presented and reveal the 3D character of the flowfield induced by projectile fins and the canting of the projectile body relative to the tube wall. Also presented for comparison to the experimental data are calculations made with an inviscid, 3D CFD code.

  10. Dynamic cerebral autoregulation measured with coherent hemodynamics spectroscopy (CHS)

    NASA Astrophysics Data System (ADS)

    Kainerstorfer, Jana M.; Sassaroli, Angelo; Tgavalekos, Kristen T.; Fantini, Sergio

    2015-03-01

    Coherent Hemodynamics Spectroscopy (CHS) is a novel technique for non-invasive measurements of local microcirculation quantities such as the capillary blood transit times and dynamic autoregulation. The basis of CHS is to measure, for instance with near-infrared spectroscopy (NIRS), peripheral coherent hemodynamic changes that are induced by controlled perturbations in the systemic mean arterial pressure (MAP). In this study, the MAP perturbation was induced by the fast release of two pneumatic cuffs placed around the subject's thighs after they were kept inflated (at 200 mmHg) for two minutes. The resulting transient changes in cerebral oxy- (O) and deoxy- (D) hemoglobin concentrations measured with NIRS on the prefrontal cortex are then described by a novel hemodynamic model, from which quantifiable parameters such as the capillary blood transit time and a cutoff frequency for cerebral autoregulation are obtained. We present results on eleven healthy volunteers in a protocol involving measurements during normal breathing and during hyperventilation, which is known to cause a hypocapnia-induced increase in cerebral autoregulation. The measured capillary transit time was unaffected by hyperventilation (normal breathing: 1.1±0.1 s; hyperventilation: 1.1±0.1 s), whereas the cutoff frequency of autoregulation, which increases for higher autoregulation efficiency, was indeed found to be significantly greater during hyperventilation (normal breathing: 0.017±0.002 Hz; hyperventilation: 0.034±0.005 Hz). These results provide a validation of local cerebral autoregulation measurements with the new technique of CHS.

  11. Coordination defects in bismuth-modified arsenic selenide glasses: High-resolution x-ray photoelectron spectroscopy measurements

    SciTech Connect

    Golovchak, Roman; Shpotyuk, Oleh

    2008-05-01

    The possibility of coordination defects formation in Bi-modified chalcogenide glasses is examined by high-resolution x-ray photoelectron spectroscopy. The results provide evidence for the formation of positively charged fourfold coordinated defects on As and Bi sites in glasses with low Bi concentration. At high Bi concentration, mixed As{sub 2}Se{sub 3}-Bi{sub 2}Se{sub 3} nanocrystallites are formed in the investigated Se-rich As-Se glasses.

  12. Statistical prediction of dynamic distortion of inlet flow using minimum dynamic measurement. An application to the Melick statistical method and inlet flow dynamic distortion prediction without RMS measurements

    NASA Technical Reports Server (NTRS)

    Schweikhard, W. G.; Chen, Y. S.

    1986-01-01

    The Melick method of inlet flow dynamic distortion prediction by statistical means is outlined. A hypothetic vortex model is used as the basis for the mathematical formulations. The main variables are identified by matching the theoretical total pressure rms ratio with the measured total pressure rms ratio. Data comparisons, using the HiMAT inlet test data set, indicate satisfactory prediction of the dynamic peak distortion for cases with boundary layer control device vortex generators. A method for the dynamic probe selection was developed. Validity of the probe selection criteria is demonstrated by comparing the reduced-probe predictions with the 40-probe predictions. It is indicated that the the number of dynamic probes can be reduced to as few as two and still retain good accuracy.

  13. Spatiotemporal Dynamics of the Wind Velocity from Minisodar Measurement Data

    NASA Astrophysics Data System (ADS)

    Simakhin, V. A.; Cherepanov, O. S.; Shamanaeva, L. G.

    2016-04-01

    The spatiotemporal dynamics of the three wind velocity components in the atmospheric boundary layer is analyzed on the basis of Doppler minisodar measurements. The data were processed and analyzed with the help of robust nonparametric methods based on the weighted maximum likelihood method and classical methods. Distribution laws were obtained for each wind velocity component. There are outliers in the distribution functions; both right and left asymmetry of the distributions are observed. For the x- and ycomponents, the width of the distribution increases as the observation altitude is increased, but the maximum of the distribution function decreases, which is in agreement with the data available in the literature. For the zcomponents the width of the distribution remains practically constant, but the value of the maximum also decreases with altitude. Analysis of the hourly semidiurnal dynamics showed that all three components have maxima in the morning and evening hours. For the y- and z-components the maxima in the evening hours are more strongly expressed than in the morning hours. For the x- and y-components the horizontal wind shear is closely tracked in the evening hours. It is shown that adaptive estimates on the efficiency significantly exceed the classical parametric estimates and allow one to analyze the spatiotemporal dynamics of the wind velocity, and reveal jets and detect wind shears.

  14. Quantitative Fluorescent Speckle Microscopy (QFSM) to Measure Actin Dynamics

    PubMed Central

    Mendoza, Michelle C.; Besson, Sebastien; Danuser, Gaudenz

    2012-01-01

    Quantitative Fluorescent Speckle Microscopy (QFSM) is a live cell imaging method to analyze the dynamics of macromolecular assemblies with high spatial and temporal resolution. Its greatest successes were in the analysis of actin filament and adhesion dynamics in the context of cell migration and microtubule dynamics in interphase and the meotic/mitotic spindle. Here, we focus on the former application to illustrate the procedures of FSM imaging and the computational image processing that extracts quantitative information from these experiments. QFSM is advantageous over other methods because it measures the movement and turnover kinetics of the actin filament (F-actin) network in living cells across the entire field of view. Experiments begin with microinjection of fluorophore-labeled actin into cells, which generate a low ratio of fluorescently-labeled:endogenous unlabeled actin monomers. Spinning disk confocal or wide-field imaging then visualizes fluorophore clusters (2–8 actin monomers) within the assembled F-actin network as speckles. QFSM software identifies and computationally tracks and utilizes the location, appearance, and disappearance of speckles to derive network flows and maps of the rate of filament assembly and disassembly. PMID:23042526

  15. Modulation measuring profilometry with cross grating projection and single shot for dynamic 3D shape measurement

    NASA Astrophysics Data System (ADS)

    Lu, Mingteng; Su, Xianyu; Cao, Yiping; You, Zhisheng; Zhong, Min

    2016-12-01

    In order to determine Dynamic 3-D shape with vertical measurement mode, a fast modulation measuring profilometry (MMP) with a cross grating projection and single shot is proposed. Unlike the previous methods, in our current projection system, one cross grating is projected by a special projection lens consisting of a common projection lens and a cylindrical lens. Due to the characteristics of cylindrical lens, the image of the vertical component and the horizontal component of the cross grating is separated in the image space, and the measuring range is just the space between the two image planes. Through a beam splitter, the CCD camera can coaxially capture the fringe pattern of the cross grating modulated by the testing object's shape. In one fringe pattern, by applying Fourier transform, filtering and inverse Fourier transform, the modulation corresponding to the vertical and horizontal components of the cross grating can be obtained respectively. Then the 3-D shape of the object can be reconstructed according to the mapping relationship between modulation and height, which was established by calibration process in advance. So the 3-D shape information can be recorded at the same speed of the frame rate of the CCD camera. This paper gives the principle of the proposed method and the set-up for measuring experiment and system calibration. The 3-D shape of a still object and a dynamic process of liquid vortex were measured and reconstructed in the experiments, and the results proved the method's feasibility. The advantage of the proposed method is that only one fringe pattern is needed to extract the modulation distribution and to reconstruct the 3-D shape of the object. Therefore, the proposed method can achieve high speed measurement and vertical measurement without shadow and occlusion. It can be used in the dynamic 3-D shape measurement and vibration analysis.

  16. A technique for measuring dynamic friction coefficient under impact loading.

    PubMed

    Lin, Y L; Qin, J G; Chen, R; Zhao, P D; Lu, F Y

    2014-09-01

    We develop a novel setup based on the split Hopkinson pressure bar technique to test the dynamic friction coefficient under impact loading. In the setup, the major improvement is that the end of the incident bar near the specimen is wedge-shaped, which results in a combined compressive and shear loading applied to the specimen. In fact, the shear loading is caused by the interfacial friction between specimen and bars. Therefore, when the two loading force histories are measured, the friction coefficient histories can be calculated without any assumptions and theoretical derivations. The geometry of the friction pairs is simple, and can be either cuboid or cylindrical. Regarding the measurements, two quartz transducers are used to directly record the force histories, and an optical apparatus is designed to test the interfacial slip movement. By using the setup, the dynamic friction coefficient of PTFE/aluminum 7075 friction pairs was tested. The time resolved dynamic friction coefficient and slip movement histories were achieved. The results show that the friction coefficient changes during the loading process, the average data of the relatively stable flat plateau section of the friction coefficient curves is 0.137, the maximum normal pressure is 52 MPa, the maximum relative slip velocity is 1.5 m/s, and the acceleration is 8400 m(2)/s. Furthermore, the friction test was simulated using an explicit FEM code LS-DYNA. The simulation results showed that the constant pressure and slip velocity can both be obtained with a wide flat plateau incident pulse. For some special friction pairs, normal pressure up to a few hundred MPa, interfacial slip velocities up to 10 m/s, and slip movement up to centimeter-level can be expected.

  17. A technique for measuring dynamic friction coefficient under impact loading

    NASA Astrophysics Data System (ADS)

    Lin, Y. L.; Qin, J. G.; Chen, R.; Zhao, P. D.; Lu, F. Y.

    2014-09-01

    We develop a novel setup based on the split Hopkinson pressure bar technique to test the dynamic friction coefficient under impact loading. In the setup, the major improvement is that the end of the incident bar near the specimen is wedge-shaped, which results in a combined compressive and shear loading applied to the specimen. In fact, the shear loading is caused by the interfacial friction between specimen and bars. Therefore, when the two loading force histories are measured, the friction coefficient histories can be calculated without any assumptions and theoretical derivations. The geometry of the friction pairs is simple, and can be either cuboid or cylindrical. Regarding the measurements, two quartz transducers are used to directly record the force histories, and an optical apparatus is designed to test the interfacial slip movement. By using the setup, the dynamic friction coefficient of PTFE/aluminum 7075 friction pairs was tested. The time resolved dynamic friction coefficient and slip movement histories were achieved. The results show that the friction coefficient changes during the loading process, the average data of the relatively stable flat plateau section of the friction coefficient curves is 0.137, the maximum normal pressure is 52 MPa, the maximum relative slip velocity is 1.5 m/s, and the acceleration is 8400 m2/s. Furthermore, the friction test was simulated using an explicit FEM code LS-DYNA. The simulation results showed that the constant pressure and slip velocity can both be obtained with a wide flat plateau incident pulse. For some special friction pairs, normal pressure up to a few hundred MPa, interfacial slip velocities up to 10 m/s, and slip movement up to centimeter-level can be expected.

  18. Dynamic measurements of actuators driven by AlN layers

    NASA Astrophysics Data System (ADS)

    Kacperski, Jacek; Kujawinska, Malgorzata; Leon, Sergio Camacho; Nieradko, Lukasz; Jozwik, Michal; Gorecki, Christophe

    2005-09-01

    Micro-Electro-Mechanical Systems are nowadays frequently used in many fields of industry. The number of their applications increase and their functions became more complex and demanding. Therefore precise knowledge about their static (shape, deformations, stresses) and dynamic (resonance frequencies, amplitude and phase of vibration) properties is necessary. Two beam laser interferometry is one of the most popular testing methods of micromechanical elements as a non-contact, high-accurate method allowing full-field measurement. First part of the paper present microbeam actuators designed for MEMS/MOEMS applications. The proposed structures are the straight silicon microbeams formed by KOH etching of Si wafer. Aluminium nitride (AlN) thin films are promising materials for many acoustic and optic applications in MEMS field. In the proposed architecture the actuation layer is sandwiched between two metal electrodes on the top of beam. In the second part we describe the methodology of the actuator characterization. These methods applied are: stroboscopic interferometry and active interferometry (LCOS SLM is used as a reference surface in Twyman-Green interferometer). Moreover some results of FEM analysis of the sample are shown and compared with experimental results. Dynamic measurements validate the design and simulations, and provide information for optimization of the actuator manufacturing process.

  19. Optimization of dynamic measurement of receptor kinetics by wavelet denoising.

    PubMed

    Alpert, Nathaniel M; Reilhac, Anthonin; Chio, Tat C; Selesnick, Ivan

    2006-04-01

    The most important technical limitation affecting dynamic measurements with PET is low signal-to-noise ratio (SNR). Several reports have suggested that wavelet processing of receptor kinetic data in the human brain can improve the SNR of parametric images of binding potential (BP). However, it is difficult to fully assess these reports because objective standards have not been developed to measure the tradeoff between accuracy (e.g. degradation of resolution) and precision. This paper employs a realistic simulation method that includes all major elements affecting image formation. The simulation was used to derive an ensemble of dynamic PET ligand (11C-raclopride) experiments that was subjected to wavelet processing. A method for optimizing wavelet denoising is presented and used to analyze the simulated experiments. Using optimized wavelet denoising, SNR of the four-dimensional PET data increased by about a factor of two and SNR of three-dimensional BP maps increased by about a factor of 1.5. Analysis of the difference between the processed and unprocessed means for the 4D concentration data showed that more than 80% of voxels in the ensemble mean of the wavelet processed data deviated by less than 3%. These results show that a 1.5x increase in SNR can be achieved with little degradation of resolution. This corresponds to injecting about twice the radioactivity, a maneuver that is not possible in human studies without saturating the PET camera and/or exposing the subject to more than permitted radioactivity.

  20. [Coupling coordination measurement of urbanization and eco-environment system in Huaihe River Basin of China based on fuzzy matter element theory].

    PubMed

    Guo, Yue-Ting; Xu, Jian-Gang

    2013-05-01

    Based on the statistical data of urbanization and eco-environment of 35 cities in the Huaihe River Basin of China in 2010, an index system of urbanization-eco-environment system was established by using fuzzy matter element theory, and the weight of each indicator was calculated by entropy method. The improved function of the coupling coordination degree of urbanization and eco-environment was constructed to measure this coupling coordination degree in the Huaihe River Basin. In 2010, the development level of urbanization subsystem in the Basin was lower than that of the eco-environment subsystem, and the integrated coordination index of urbanization and eco-environment was 0.186, indicating that there was a gap between the two types of indicators. The average coupling degree of urbanization and eco-environment was 0.475, indicating that the urbanization-eco-environment system was at antagonistic stage. There was a greater difference in the development level of urbanization subsystem, but a smaller difference in the development level of eco-environment subsystem among the cities. The average value of the coordination degree of all the cities was 0.706, indicating that the Huaihe River Basin was at high coordination coupling stage, and the integrated coherence and synergistic effect of urbanization and eco-environment construction in the Huaihe River Basin was higher.

  1. A Coordinated Ice-based and Airborne Snow and Ice Thickness Measurement Campaign on Arctic Sea Ice

    NASA Astrophysics Data System (ADS)

    Richter-Menge, J.; Farrell, S.; Elder, B. C.; Gardner, J. M.; Brozena, J. M.

    2011-12-01

    A rare opportunity presented itself in March 2011 when the Naval Research Laboratory (NRL) and NASA IceBridge teamed with scientists from the U.S. Army Corps of Engineers Cold Regions Research and Engineering Laboratory (CRREL) to coordinate a multi-scale approach to mapping snow depth and sea ice thickness distribution in the Arctic. Ground-truth information for calibration/validation of airborne and CryoSat-2 satellite data were collected near a manned camp deployed in support of the US Navy's Ice Expedition 2011 (ICEX 2011). The ice camp was established at a location approximately 230 km north of Prudhoe Bay, Alaska, at the edge of the perennial ice zone. The suite of measurements was strategically organized around a 9-km-long survey line that covered a wide range of ice types, including refrozen leads, deformed and undeformed first year ice, and multiyear ice. A highly concentrated set of in situ measurements of snow depth and ice thickness were taken along the survey line. Once the survey line was in place, NASA IceBridge flew a dedicated mission along the survey line, collecting data with an instrument suite that included the Airborne Topographic Mapper (ATM), a high precision, airborne scanning laser altimeter; the Digital Mapping System (DMS), nadir-viewing digital camera; and the University of Kansas ultra-wideband Frequency Modulated Continuous Wave (FMCW) snow radar. NRL also flew a dedicated mission over the survey line with complementary airborne radar, laser and photogrammetric sensors (see Brozena et al., this session). These measurements were further leveraged by a series of CryoSat-2 under flights made in the region by the instrumented NRL and NASA planes, as well as US Navy submarine underpasses of the 9-km-long survey line to collect ice draft measurements. This comprehensive suite of data provides the full spectrum of sampling resolutions from satellite, to airborne, to ground-based, to submarine and will allow for a careful determination of

  2. Spatio-temporal co-ordination of RhoA, Rac1 and Cdc42 activation during prototypical edge protrusion and retraction dynamics

    PubMed Central

    Martin, Katrin; Reimann, Andreas; Fritz, Rafael D.; Ryu, Hyunryul; Jeon, Noo Li; Pertz, Olivier

    2016-01-01

    The three canonical Rho GTPases RhoA, Rac1 and Cdc42 co-ordinate cytoskeletal dynamics. Recent studies indicate that all three Rho GTPases are activated at the leading edge of motile fibroblasts, where their activity fluctuates at subminute time and micrometer length scales. Here, we use a microfluidic chip to acutely manipulate fibroblast edge dynamics by applying pulses of platelet-derived growth factor (PDGF) or the Rho kinase inhibitor Y-27632 (which lowers contractility). This induces acute and robust membrane protrusion and retraction events, that exhibit stereotyped cytoskeletal dynamics, allowing us to fairly compare specific morphodynamic states across experiments. Using a novel Cdc42, as well as previously described, second generation RhoA and Rac1 biosensors, we observe distinct spatio-temporal signaling programs that involve all three Rho GTPases, during protrusion/retraction edge dynamics. Our results suggest that Rac1, Cdc42 and RhoA regulate different cytoskeletal and adhesion processes to fine tune the highly plastic edge protrusion/retraction dynamics that power cell motility. PMID:26912264

  3. Z-correction, a method for achieving ultraprecise self-calibration on large area coordinate measurement machines for photomasks

    NASA Astrophysics Data System (ADS)

    Ekberg, Peter; Stiblert, Lars; Mattsson, Lars

    2014-05-01

    High-quality photomasks are a prerequisite for the production of flat panel TVs, tablets and other kinds of high-resolution displays. During the past years, the resolution demand has become more and more accelerated, and today, the high-definition standard HD, 1920 × 1080 pixels2, is well established, and already the next-generation so-called ultra-high-definition UHD or 4K display is entering the market. Highly advanced mask writers are used to produce the photomasks needed for the production of such displays. The dimensional tolerance in X and Y on absolute pattern placement on these photomasks, with sizes of square meters, has been in the range of 200-300 nm (3σ), but is now on the way to be <150 nm (3σ). To verify these photomasks, 2D ultra-precision coordinate measurement machines are used with even tighter tolerance requirements. The metrology tool MMS15000 is today the world standard tool used for the verification of large area photomasks. This paper will present a method called Z-correction that has been developed for the purpose of improving the absolute X, Y placement accuracy of features on the photomask in the writing process. However, Z-correction is also a prerequisite for achieving X and Y uncertainty levels <90 nm (3σ) in the self-calibration process of the MMS15000 stage area of 1.4 × 1.5 m2. When talking of uncertainty specifications below 200 nm (3σ) of such a large area, the calibration object used, here an 8-16 mm thick quartz plate of size approximately a square meter, cannot be treated as a rigid body. The reason for this is that the absolute shape of the plate will be affected by gravity and will therefore not be the same at different places on the measurement machine stage when it is used in the self-calibration process. This mechanical deformation will stretch or compress the top surface (i.e. the image side) of the plate where the pattern resides, and therefore spatially deform the mask pattern in the X- and Y-directions. Errors due

  4. Accurately measuring dynamic coefficient of friction in ultraform finishing

    NASA Astrophysics Data System (ADS)

    Briggs, Dennis; Echaves, Samantha; Pidgeon, Brendan; Travis, Nathan; Ellis, Jonathan D.

    2013-09-01

    UltraForm Finishing (UFF) is a deterministic sub-aperture computer numerically controlled grinding and polishing platform designed by OptiPro Systems. UFF is used to grind and polish a variety of optics from simple spherical to fully freeform, and numerous materials from glasses to optical ceramics. The UFF system consists of an abrasive belt around a compliant wheel that rotates and contacts the part to remove material. This work aims to accurately measure the dynamic coefficient of friction (μ), how it changes as a function of belt wear, and how this ultimately affects material removal rates. The coefficient of friction has been examined in terms of contact mechanics and Preston's equation to determine accurate material removal rates. By accurately predicting changes in μ, polishing iterations can be more accurately predicted, reducing the total number of iterations required to meet specifications. We have established an experimental apparatus that can accurately measure μ by measuring triaxial forces during translating loading conditions or while manufacturing the removal spots used to calculate material removal rates. Using this system, we will demonstrate μ measurements for UFF belts during different states of their lifecycle and assess the material removal function from spot diagrams as a function of wear. Ultimately, we will use this system for qualifying belt-wheel-material combinations to develop a spot-morphing model to better predict instantaneous material removal functions.

  5. Dynamic wall shear stress measurements in a turbulent channel flow

    NASA Astrophysics Data System (ADS)

    Amili, Omid; Soria, Julio

    2010-11-01

    To quantify and understand the dynamics of near wall momentum transfer, high spatial resolution, time-resolved measurements of wall shear stress distribution are essential. In this study, a film-based shear stress sensor has been used to measure the time-resolved local wall shear stress distribution in a turbulent channel flow. Measurements have been undertaken in a turbulent channel flow at Reynolds numbers up to 130,000 based on the bulk velocity and channel height. The measured fluctuating wall shear stress distribution provides spatio-temporal information of the characteristics of near wall structures by detecting their footprints. The span-wise extent of the positive two-point correlation of the stream-wise shear stress fluctuations provides the average width in the order of 100 wall units for the near-wall coherent structures. An investigation of the topological features of the velocity gradient and rate of strain tensors enables us to show an intrinsic characteristic of the near wall flow, which follows a two-dimensional flow pattern.

  6. Reinforcement learning for partially observable dynamic processes: adaptive dynamic programming using measured output data.

    PubMed

    Lewis, F L; Vamvoudakis, Kyriakos G

    2011-02-01

    Approximate dynamic programming (ADP) is a class of reinforcement learning methods that have shown their importance in a variety of applications, including feedback control of dynamical systems. ADP generally requires full information about the system internal states, which is usually not available in practical situations. In this paper, we show how to implement ADP methods using only measured input/output data from the system. Linear dynamical systems with deterministic behavior are considered herein, which are systems of great interest in the control system community. In control system theory, these types of methods are referred to as output feedback (OPFB). The stochastic equivalent of the systems dealt with in this paper is a class of partially observable Markov decision processes. We develop both policy iteration and value iteration algorithms that converge to an optimal controller that requires only OPFB. It is shown that, similar to Q -learning, the new methods have the important advantage that knowledge of the system dynamics is not needed for the implementation of these learning algorithms or for the OPFB control. Only the order of the system, as well as an upper bound on its "observability index," must be known. The learned OPFB controller is in the form of a polynomial autoregressive moving-average controller that has equivalent performance with the optimal state variable feedback gain.

  7. MEASURING THE MASS OF 4UO900-40 DYNAMICALLY

    NASA Technical Reports Server (NTRS)

    Dolan, J. F.; Etzel, Paul B.; Boyd, Patricia T.

    2006-01-01

    Accurate measurements of neutron star masses are needed to constrain the equation of state of neutron star matter - of importance to both particle physics and the astrophysics of neutron stars - and to identify the evolutionary track of the progenitor stars that form neutron stars. The best measured values of the mass of 4UO900-40 (= Vela XR-l), 1.86 +/- 0.16 Msun (Barziv et al. 2001) and 1.93 +/- 0.20 Msun (Abubekerov et al. 2004), make it a leading candidate for the most massive neutron star known. The direct relationship between the maximum mass of neutron stars and the equation of state of ultra-dense matter makes 4UO900-40 an important neutron star mass to determine accurately. The confidence interval on previous mass estimates, obtained from observations that include parameters determined by non-dynamical methods, are not small enough to significantly restrict possible equations of state. We describe here a purely dynamical method for determining the mass of 4UO900-40, an X-ray pulsar, using the reprocessed UV pulses emitted by its BO.5Ib companion. One can derive the instantaneous radial velocity of each component by simultaneous X-ray and UV observations at the two quadratures of the system. The Doppler shift caused by the primary's rotational velocity and the illumination pattern of the X-rays on the primary, two of the three principal contributors to the uncertainty on the derived mass of the neutron star, almost exactly cancel by symmetry in this method. A heuristic measurement of the mass of 4UO900-40 using observations obtained previously with the High Speed Photometer on HST is given in Appendix A.

  8. Dynamic light-scattering measurement comparability of nanomaterial suspensions

    NASA Astrophysics Data System (ADS)

    Nickel, Carmen; Angelstorf, Judith; Bienert, Ralf; Burkart, Corinna; Gabsch, Stephan; Giebner, Sabrina; Haase, Andrea; Hellack, Bryan; Hollert, Henner; Hund-Rinke, Kerstin; Jungmann, Dirk; Kaminski, Heinz; Luch, Andreas; Maes, Hanna M.; Nogowski, André; Oetken, Matthias; Schaeffer, Andreas; Schiwy, Andreas; Schlich, Karsten; Stintz, Michael; von der Kammer, Frank; Kuhlbusch, Thomas A. J.

    2014-02-01

    Increased use of nanomaterials in everyday products leads to their environmental release and therefore, the information need on their fate and behaviour. Nanomaterials have to be suspended with high repeatability and comparability for studies on environmental effects. They also have to be well characterised with a focus on the state of agglomeration and particle size distribution. Dynamic light-scattering (DLS) is a common technique used for these measurements. If suspensions are prepared in different laboratories, then concern has risen about the comparability of the measured results, especially when different DLS instruments are used. Therefore, for quality assurance, a round-robin test was conducted to assess the comparability of different DLS instruments and a dispersion protocol in ten independent laboratories. Polystyrene and TiO2 were chosen as test (nano)materials. For the comparability of the DLS instruments, the average sizes of the PSL and a stabilised TiO2 suspension were measured. The measured average hydrodynamic diameter shows an overall good inter-laboratory comparability. For the PSL suspension, an average hydrodynamic diameter of 201 ± 13 nm and for the TiO2 suspension an average diameter of 224 ± 24 nm were detected. For the TiO2 suspension that was prepared at each laboratory following an established suspension preparation protocol, an average hydrodynamic diameter of 211 ± 11 nm was detected. The measured average particle size (mode) increased up to 284 nm with a high standard deviation of 119 nm if the preparation protocol could not established and different procedures or different equipment were employed. This study shows that no significant differences between the employed DLS instrument types were determined. It was also shown that comparable measurements and suspension preparation could be achieved if well-defined suspension preparation protocols and comparable equipment can be used.

  9. Quantum molecular dynamics of hydrogen bonded complexes of rigid molecules using the semiclassical initial value representation in Cartesian coordinates.

    PubMed

    Issack, Bilkiss B; Roy, Pierre-Nicholas

    2007-08-07

    Semiclassical initial value representation calculations are performed for the constrained water dimer in Cartesian coordinates. The study represents the first application of a previously reported method [Issak and Roy, J. Chem. Phys. 123, 084103 (2005); 126, 024111 (2007)] to a molecular cluster. Bound state energies are calculated for a dimer of rigid water molecules (H2O)2 as well as its deuterated form (D2O)2. The results show that the approach fares well with respect to accuracy in capturing quantum effects in intermolecular interactions.

  10. Structural anomaly and dynamic heterogeneity in cycloether/water binary mixtures: Signatures from composition dependent dynamic fluorescence measurements and computer simulations

    NASA Astrophysics Data System (ADS)

    Indra, Sandipa; Guchhait, Biswajit; Biswas, Ranjit

    2016-03-01

    We have performed steady state UV-visible absorption and time-resolved fluorescence measurements and computer simulations to explore the cosolvent mole fraction induced changes in structural and dynamical properties of water/dioxane (Diox) and water/tetrahydrofuran (THF) binary mixtures. Diox is a quadrupolar solvent whereas THF is a dipolar one although both are cyclic molecules and represent cycloethers. The focus here is on whether these cycloethers can induce stiffening and transition of water H-bond network structure and, if they do, whether such structural modification differentiates the chemical nature (dipolar or quadrupolar) of the cosolvent molecules. Composition dependent measured fluorescence lifetimes and rotation times of a dissolved dipolar solute (Coumarin 153, C153) suggest cycloether mole-fraction (XTHF/Diox) induced structural transition for both of these aqueous binary mixtures in the 0.1 ≤ XTHF/Diox ≤ 0.2 regime with no specific dependence on the chemical nature. Interestingly, absorption measurements reveal stiffening of water H-bond structure in the presence of both the cycloethers at a nearly equal mole-fraction, XTHF/Diox ˜ 0.05. Measurements near the critical solution temperature or concentration indicate no role for the solution criticality on the anomalous structural changes. Evidences for cycloether aggregation at very dilute concentrations have been found. Simulated radial distribution functions reflect abrupt changes in respective peak heights at those mixture compositions around which fluorescence measurements revealed structural transition. Simulated water coordination numbers (for a dissolved C153) and number of H-bonds also exhibit minima around these cosolvent concentrations. In addition, several dynamic heterogeneity parameters have been simulated for both the mixtures to explore the effects of structural transition and chemical nature of cosolvent on heterogeneous dynamics of these systems. Simulated four-point dynamic

  11. Measurement of dynamic surface tension by mechanically vibrated sessile droplets.

    PubMed

    Iwata, Shuichi; Yamauchi, Satoko; Yoshitake, Yumiko; Nagumo, Ryo; Mori, Hideki; Kajiya, Tadashi

    2016-04-01

    We developed a novel method for measuring the dynamic surface tension of liquids using mechanically vibrated sessile droplets. Under continuous mechanical vibration, the shape of the deformed droplet was fitted by numerical analysis, taking into account the force balance at the drop surface and the momentum equation. The surface tension was determined by optimizing four parameters: the surface tension, the droplet's height, the radius of the droplet-substrate contact area, and the horizontal symmetrical position of the droplet. The accuracy and repeatability of the proposed method were confirmed using drops of distilled water as well as viscous aqueous glycerol solutions. The vibration frequency had no influence on surface tension in the case of pure liquids. However, for water-soluble surfactant solutions, the dynamic surface tension gradually increased with vibration frequency, which was particularly notable for low surfactant concentrations slightly below the critical micelle concentration. This frequency dependence resulted from the competition of two mechanisms at the drop surface: local surface deformation and surfactant transport towards the newly generated surface.

  12. Measurement of dynamic surface tension by mechanically vibrated sessile droplets

    NASA Astrophysics Data System (ADS)

    Iwata, Shuichi; Yamauchi, Satoko; Yoshitake, Yumiko; Nagumo, Ryo; Mori, Hideki; Kajiya, Tadashi

    2016-04-01

    We developed a novel method for measuring the dynamic surface tension of liquids using mechanically vibrated sessile droplets. Under continuous mechanical vibration, the shape of the deformed droplet was fitted by numerical analysis, taking into account the force balance at the drop surface and the momentum equation. The surface tension was determined by optimizing four parameters: the surface tension, the droplet's height, the radius of the droplet-substrate contact area, and the horizontal symmetrical position of the droplet. The accuracy and repeatability of the proposed method were confirmed using drops of distilled water as well as viscous aqueous glycerol solutions. The vibration frequency had no influence on surface tension in the case of pure liquids. However, for water-soluble surfactant solutions, the dynamic surface tension gradually increased with vibration frequency, which was particularly notable for low surfactant concentrations slightly below the critical micelle concentration. This frequency dependence resulted from the competition of two mechanisms at the drop surface: local surface deformation and surfactant transport towards the newly generated surface.

  13. Methodological aspects of EEG and body dynamics measurements during motion

    PubMed Central

    Reis, Pedro M. R.; Hebenstreit, Felix; Gabsteiger, Florian; von Tscharner, Vinzenz; Lochmann, Matthias

    2014-01-01

    EEG involves the recording, analysis, and interpretation of voltages recorded on the human scalp which originate from brain gray matter. EEG is one of the most popular methods of studying and understanding the processes that underlie behavior. This is so, because EEG is relatively cheap, easy to wear, light weight and has high temporal resolution. In terms of behavior, this encompasses actions, such as movements that are performed in response to the environment. However, there are methodological difficulties which can occur when recording EEG during movement such as movement artifacts. Thus, most studies about the human brain have examined activations during static conditions. This article attempts to compile and describe relevant methodological solutions that emerged in order to measure body and brain dynamics during motion. These descriptions cover suggestions on how to avoid and reduce motion artifacts, hardware, software and techniques for synchronously recording EEG, EMG, kinematics, kinetics, and eye movements during motion. Additionally, we present various recording systems, EEG electrodes, caps and methods for determinating real/custom electrode positions. In the end we will conclude that it is possible to record and analyze synchronized brain and body dynamics related to movement or exercise tasks. PMID:24715858

  14. Microsensor measurements of hydrogen gas dynamics in cyanobacterial microbial mats.

    PubMed

    Nielsen, Michael; Revsbech, Niels P; Kühl, Michael

    2015-01-01

    We used a novel amperometric microsensor for measuring hydrogen gas production and consumption at high spatio-temporal resolution in cyanobacterial biofilms and mats dominated by non-heterocystous filamentous cyanobacteria (Microcoleus chtonoplastes and Oscillatoria sp.). The new microsensor is based on the use of an organic electrolyte and a stable internal reference system and can be equipped with a chemical sulfide trap in the measuring tip; it exhibits very stable and sulfide-insensitive measuring signals and a high sensitivity (1.5-5 pA per μmol L(-1) H2). Hydrogen gas measurements were done in combination with microsensor measurements of scalar irradiance, O2, pH, and H2S and showed a pronounced H2 accumulation (of up to 8-10% H2 saturation) within the upper mm of cyanobacterial mats after onset of darkness and O2 depletion. The peak concentration of H2 increased with the irradiance level prior to darkening. After an initial build-up over the first 1-2 h in darkness, H2 was depleted over several hours due to efflux to the overlaying water, and due to biogeochemical processes in the uppermost oxic layers and the anoxic layers of the mats. Depletion could be prevented by addition of molybdate pointing to sulfate reduction as a major sink for H2. Immediately after onset of illumination, a short burst of presumably photo-produced H2 due to direct biophotolysis was observed in the illuminated but anoxic mat layers. As soon as O2 from photosynthesis started to accumulate, the H2 was consumed rapidly and production ceased. Our data give detailed insights into the microscale distribution and dynamics of H2 in cyanobacterial biofilms and mats, and further support that cyanobacterial H2 production can play a significant role in fueling anaerobic processes like e.g., sulfate reduction or anoxygenic photosynthesis in microbial mats.

  15. Microsensor measurements of hydrogen gas dynamics in cyanobacterial microbial mats

    PubMed Central

    Nielsen, Michael; Revsbech, Niels P.; Kühl, Michael

    2015-01-01

    We used a novel amperometric microsensor for measuring hydrogen gas production and consumption at high spatio-temporal resolution in cyanobacterial biofilms and mats dominated by non-heterocystous filamentous cyanobacteria (Microcoleus chtonoplastes and Oscillatoria sp.). The new microsensor is based on the use of an organic electrolyte and a stable internal reference system and can be equipped with a chemical sulfide trap in the measuring tip; it exhibits very stable and sulfide-insensitive measuring signals and a high sensitivity (1.5–5 pA per μmol L-1 H2). Hydrogen gas measurements were done in combination with microsensor measurements of scalar irradiance, O2, pH, and H2S and showed a pronounced H2 accumulation (of up to 8–10% H2 saturation) within the upper mm of cyanobacterial mats after onset of darkness and O2 depletion. The peak concentration of H2 increased with the irradiance level prior to darkening. After an initial build-up over the first 1–2 h in darkness, H2 was depleted over several hours due to efflux to the overlaying water, and due to biogeochemical processes in the uppermost oxic layers and the anoxic layers of the mats. Depletion could be prevented by addition of molybdate pointing to sulfate reduction as a major sink for H2. Immediately after onset of illumination, a short burst of presumably photo-produced H2 due to direct biophotolysis was observed in the illuminated but anoxic mat layers. As soon as O2 from photosynthesis started to accumulate, the H2 was consumed rapidly and production ceased. Our data give detailed insights into the microscale distribution and dynamics of H2 in cyanobacterial biofilms and mats, and further support that cyanobacterial H2 production can play a significant role in fueling anaerobic processes like e.g., sulfate reduction or anoxygenic photosynthesis in microbial mats. PMID:26257714

  16. Characterizing Suspension Plasma Spray Coating Formation Dynamics through Curvature Measurements

    NASA Astrophysics Data System (ADS)

    Chidambaram Seshadri, Ramachandran; Dwivedi, Gopal; Viswanathan, Vaishak; Sampath, Sanjay

    2016-12-01

    Suspension plasma spraying (SPS) enables the production of variety of microstructures with unique mechanical and thermal properties. In SPS, a liquid carrier (ethanol/water) is used to transport the sub-micrometric feedstock into the plasma jet. Considering complex deposition dynamics of SPS technique, there is a need to better understand the relationships among spray conditions, ensuing particle behavior, deposition stress evolution and resultant properties. In this study, submicron yttria-stabilized zirconia particles suspended in ethanol were sprayed using a cascaded arc plasma torch. The stresses generated during the deposition of the layers (termed evolving stress) were monitored via the change in curvature of the substrate measured using an in situ measurement apparatus. Depending on the deposition conditions, coating microstructures ranged from feathery porous to dense/cracked deposits. The evolving stresses and modulus were correlated with the observed microstructures and visualized via process maps. Post-deposition bi-layer curvature measurement via low temperature thermal cycling was carried out to quantify the thermo-elastic response of different coatings. Lastly, preliminary data on furnace cycle durability of different coating microstructures were evaluated. This integrated study involving in situ diagnostics and ex situ characterization along with process maps provides a framework to describe coating formation mechanisms, process parametrics and microstructure description.

  17. The effect of the dynamic wet troposphere on VLBI measurements

    NASA Technical Reports Server (NTRS)

    Treuhaft, R. N.; Lanyi, G. E.

    1986-01-01

    Calculations using a statistical model of water vapor fluctuations yield the effect of the dynamic wet troposphere on Very Long Baseline Interferometry (VLBI) measurements. The statistical model arises from two primary assumptions: (1) the spatial structure of refractivity fluctuations can be closely approximated by elementary (Kolmogorov) turbulence theory, and (2) temporal fluctuations are caused by spatial patterns which are moved over a site by the wind. The consequences of these assumptions are outlined for the VLBI delay and delay rate observables. For example, wet troposphere induced rms delays for Deep Space Network (DSN) VLBI at 20-deg elevation are about 3 cm of delay per observation, which is smaller, on the average, than other known error sources in the current DSN VLBI data set. At 20-deg elevation for 200-s time intervals, water vapor induces approximately 1.5 x 10 to the minus 13th power s/s in the Allan standard deviation of interferometric delay, which is a measure of the delay rate observable error. In contrast to the delay error, the delay rate measurement error is dominated by water vapor fluctuations. Water vapor induced VLBI parameter errors and correlations are calculated. For the DSN, baseline length parameter errors due to water vapor fluctuations are in the range of 3 to 5 cm. The above physical assumptions also lead to a method for including the water vapor fluctuations in the parameter estimation procedure, which is used to extract baseline and source information from the VLBI observables.

  18. Dual interferometer for dynamic measurement of corneal topography

    NASA Astrophysics Data System (ADS)

    Micali, Jason D.; Greivenkamp, John E.

    2016-08-01

    The cornea is the anterior most surface of the eye and plays a critical role in vision. A thin fluid layer, the tear film, coats the outer surface of the cornea and serves to protect, nourish, and lubricate the cornea. At the same time, the tear film is responsible for creating a smooth continuous surface, where the majority of refraction takes place in the eye. A significant component of vision quality is determined by the shape of the cornea and stability of the tear film. A dual interferometer system for measuring the dynamic corneal topography is designed, built, verified, and qualified by testing on human subjects. The system consists of two coaligned simultaneous phase-shifting polarization-splitting Twyman-Green interferometers. The primary interferometer measures the surface of the tear film while the secondary interferometer tracks the absolute position of the cornea, which provides enough information to reconstruct the absolute shape of the cornea. The results are high-resolution and high-accuracy surface topography measurements of the in vivo tear film and cornea that are captured at standard camera frame rates.

  19. Thermographic measurement of thermal bridges in buildings under dynamic behavior

    NASA Astrophysics Data System (ADS)

    Ferrarini, G.; Bison, P.; Bortolin, A.; Cadelano, G.; De Carli, M.

    2016-05-01

    The accurate knowledge of the thermal performance could reduce significantly the impact of buildings on global energy consumption. Infrared thermography is widely recognized as one of the key technologies for building surveys, thanks to its ability to acquire at a glance thermal images of the building envelope. However, a spot measurement could be misleading when the building is under dynamic thermal conditions. In this case data should be acquired for hours or days, depending on the thermal properties of the walls. Long term thermographic monitoring are possible but imply strong challenges from a practical standpoint. This work investigates the possibilities and limitations of spot thermographic surveys coupled with contact probes, that are able to acquire continuously the thermal signal for days, to investigate the thermal bridges of a building. The goal is the estimation of the reliability and accuracy of the measurement under realistic environmental conditions. Firstly, numerical simulations are performed to determine the reference value of an experimental case. Then a long term thermographic survey is performed and integrated with the contact probe measurement, assessing the feasibility of the method.

  20. Optical measurement methods to study dynamic behavior in MEMS

    NASA Astrophysics Data System (ADS)

    Rembe, Christian; Kant, Rishi; Muller, Richard S.

    2001-10-01

    The maturing designs of moving microelectromechanical systems (MEMS) make it more-and-more important to have precise measurements and visual means to characterize dynamic microstructures. The Berkeley Sensor&Actuator Center (BSAC) has a forefront project aimed at developing these capabilities and at providing high-speed Internet (Supernet) access for remote use of its facilities. Already in operation are three optical-characterization tools: a stroboscopic-interferometer system, a computer-microvision system, and a laser-Doppler vibrometer. This paper describes precision and limitations of these systems and discusses their further development. In addition, we describe the results of experimental studies on the different MEMS devices, and give an overview about high-speed visualization of rapidly moving MEMS structures.

  1. Ultrasonic Measurement of Dynamic Muscle Behavior for Poststroke Hemiparetic Gait

    PubMed Central

    Chen, Xin; Shi, Wenxiu; Wang, Jun; Xiang, Yun

    2017-01-01

    Quantitative evaluation of the hemiparesis status for a poststroke patient is still challenging. This study aims to measure and investigate the dynamic muscle behavior in poststroke hemiparetic gait using ultrasonography. Twelve hemiparetic patients walked on a treadmill, and EMG, joint angle, and ultrasonography were simultaneously recorded for the gastrocnemius medialis muscle. Pennation angle was automatically extracted from ultrasonography using a tracking algorithm reported previously. The characteristics of EMG, joint angle, and pennation angle in gait cycle were calculated for both (affected and unaffected) sides of lower limbs. The results suggest that pennation angle could work as an important morphological index to continuous muscle contraction. The change pattern of pennation angle between the affected and unaffected sides is different from that of EMG. These findings indicate that morphological parameter extracted from ultrasonography can provide different information from that provided by EMG for hemiparetic gait. PMID:28232945

  2. Coordinated Interaction of Down Syndrome Cell Adhesion Molecule (DSCAM) nd Deleted in Colorectal Cancer (DCC) with Dynamic TUBB3 Mediates Netrin-1-Induced Axon Branching

    PubMed Central

    Huang, Huai; Shao, Qiangqiang; Qu, Chao; Yang, Tao; Dwyer, Trisha; Liu, Guofa

    2015-01-01

    Modulation of actin and microtubule (MT) dynamics in neurons is implicated in guidance cue-dependent axon outgrowth, branching and pathfinding. Although the role of MTs in axon guidance has been well known, how extracellular guidance signals engage MT behavior in axon branching remains unclear. Previously, we have shown that TUBB3, the most dynamic β-tubulin isoform in neurons, directly binds to DCC to regulate MT dynamics in Netrin-1-mediated axon guidance. Here, we report that TUBB3 directly interacted with another Netrin-1 receptor DSCAM and Netrin-1 increased this interaction in primary neurons. MT dynamics were required for Netrin-1-promoted association of DSCAM with TUBB3. Knockdown of either DSCAM or DCC or addition of a function blocking anti-DCC antibody mutually blocked Netrin-1-induced interactions, suggesting that DSCAM interdependently coordinated with DCC in Netrin-1-induced binding to TUBB3. Both DSCAM and DCC were partially colocalized with TUBB3 in the axon branch and the axon branching point of primary neurons and Netrin-1 increased these colocalizations. Netrin-1 induced the interaction of endogenous DSCAM with polymerized TUBB3 in primary neurons and Src family kinases (SFKs) were required for regulating this binding. Knockdown of DSCAM only, DCC only or both was sufficient to block Netrin-1-induced axon branching of E15 mouse cortical neurons. Knocking down TUBB3 inhibited Netrin-1 induced axon branching as well. These results suggest that DSCAM collaborates with DCC to regulate MT dynamics via direct binding to dynamic TUBB3 in Netrin-1-induced axon branching. PMID:25754961

  3. A Full Mission Simulator Study of Aircrew Performances: the Measurement of Crew Coordination and Decisionmaking Factors and Their Relationships to Flight Task Performances

    NASA Technical Reports Server (NTRS)

    Murphy, M. R.; Randle, R. J.; Tanner, T. A.; Frankel, R. M.; Goguen, J. A.; Linde, C.

    1984-01-01

    Sixteen three man crews flew a full mission scenario in an airline flight simulator. A high level of verbal interaction during instances of critical decision making was located. Each crew flew the scenario only once, without prior knowledge of the scenario problem. Following a simulator run and in accord with formal instructions, each of the three crew members independently viewed and commented on a videotape of their performance. Two check pilot observers rated pilot performance across all crews and, following each run, also commented on the video tape of the crew's performance. A linguistic analysis of voice transcript is made to provide assessment of crew coordination and decision making qualities. Measures of crew coordination and decision making factors are correlated with flight task performance measures.

  4. Dynamical Structure of Venus' Middle Atmosphere Constrained by Direct Wind Measurements

    NASA Astrophysics Data System (ADS)

    Widemann, Thomas; Lellouch, E.; Luz, D.; Moreno, R.

    2006-09-01

    Dynamical study of Venus' mesosphere from Venus Express will largely rely on temperature measurements, cloud motion tracking and the structure of non-LTE O2 and CO2 emissions. However, direct wind measurements can only be provided using high spectral resolution (105-107) ground-based facilities measuring Doppler shifts in CO and isotopic 13CO rotational millimeter lines (95-115 km), solar Fraunhofer (67 km) and CO2 5ν3 lines (74 km), or O emission line at 557 nm (100 km). Following our observations in 2001 and 2002 [1], we report new wind measurements using OHP 1.5-m/Aurélie (R 120,000) in April 2006. We measured drastic time variability of the lower mesospheric zonal wind field over a 24-h period, sometimes on the hour time scale, with equatorial zonal velocities about 0-20 ms-1 in CO2 lines on Apr. 22 (about 30 ms-1 in solar lines) and 125-195 ms-1 in CO2 lines on Apr. 23 (95-115 ms-1 in solar lines). The difference of altitude estimate probed by the two sets of lines, near 67 km for the solar lines, and about 74 km for the CO2 5ν3 lines, indicates that the general agreement between wind values inferred from the two types of lines support the case for a negligible wind shear over two scale heights near and above clouds top. Although the characteristic timescales of zonal wind variations in the visible lines are the same as those measured in CO millimeter lines [2], the vertical gradient of zonal wind appears negligible in the visible but reveals a strong vertical shear in CO data over 95-115 km. Future coordinated observations at various wavelengths from the ground, will investigate the dynamical coupling between different altitude levels and provide independent wind measurements at various altitudes. [1] Widemann et al, 2006, Planet Space Sci., in press. [2] Clancy et al. 2005, BAAS. 37, n°3, 54.04

  5. Dynamic measurements and uncertainty estimation of clinical thermometers using Monte Carlo method

    NASA Astrophysics Data System (ADS)

    Ogorevc, Jaka; Bojkovski, Jovan; Pušnik, Igor; Drnovšek, Janko

    2016-09-01

    Clinical thermometers in intensive care units are used for the continuous measurement of body temperature. This study describes a procedure for dynamic measurement uncertainty evaluation in order to examine the requirements for clinical thermometer dynamic properties in standards and recommendations. In this study thermistors were used as temperature sensors, transient temperature measurements were performed in water and air and the measurement data were processed for the investigation of thermometer dynamic properties. The thermometers were mathematically modelled. A Monte Carlo method was implemented for dynamic measurement uncertainty evaluation. The measurement uncertainty was analysed for static and dynamic conditions. Results showed that dynamic uncertainty is much larger than steady-state uncertainty. The results of dynamic uncertainty analysis were applied on an example of clinical measurements and were compared to current requirements in ISO standard for clinical thermometers. It can be concluded that there was no need for dynamic evaluation of clinical thermometers for continuous measurement, while dynamic measurement uncertainty was within the demands of target uncertainty. Whereas in the case of intermittent predictive thermometers, the thermometer dynamic properties had a significant impact on the measurement result. Estimation of dynamic uncertainty is crucial for the assurance of traceable and comparable measurements.

  6. Markov stochasticity coordinates

    NASA Astrophysics Data System (ADS)

    Eliazar, Iddo

    2017-01-01

    Markov dynamics constitute one of the most fundamental models of random motion between the states of a system of interest. Markov dynamics have diverse applications in many fields of science and engineering, and are particularly applicable in the context of random motion in networks. In this paper we present a two-dimensional gauging method of the randomness of Markov dynamics. The method-termed Markov Stochasticity Coordinates-is established, discussed, and exemplified. Also, the method is tweaked to quantify the stochasticity of the first-passage-times of Markov dynamics, and the socioeconomic equality and mobility in human societies.

  7. Dynamic-structure-factor measurements on a model Lorentz gas

    NASA Astrophysics Data System (ADS)

    Egelstaff, P. A.; Eder, O. J.; Glaser, W.; Polo, J.; Renker, B.; Soper, A. K.

    1990-02-01

    A model system for the Lorentz gas can be made [Eder, Chen, and Egelstaff, Proc. Phys. Soc. London 89, 833 (1966); McPherson and Egelstaff, Can. J. Phys. 58, 289 (1980)] by mixing small quantities of hydrogen with an argon host. For neutron-scattering experiments the large H-to-Ar cross section ratio (~200) makes the argon relatively invisible. Dynamic-structure-factor [S(Q,ω) for H2] measurements at room temperature have been made on this system using the IN4 spectrometer at the Institute Laue Langevin, Grenoble, France. Argon densities between 1.9 and 10.5 atoms/nm3 were used for 0.4measurements were made with a He gas host at densities of 4 and 10.5 atoms/nm3; helium is relatively invisible also compared to hydrogen. These experiments are described, and some examples of the results are presented to show the qualitative effects observed. The principle observation is a pronounced narrowing of S(Q,ω) as a function of ω as the argon density is increased. This effect is large at low Q and decreases with increasing Q, and also decreases substantially when helium is used in place of argon. In addition, the shape of S(Q,ω) is more complex than can be accommodated within a simple model, but slightly less complicated than a computer simulation so showing the significance of multiple-collision processes.

  8. Ultrafast Magnetism Dynamics Measure Using Tabletop Ultrafast EUV Sources

    SciTech Connect

    Silva, Thomas J.; Murnane, Margaret

    2013-08-21

    In our work to date, we made two significant advances. First we demonstrated element-selective demagnetization dynamics for the first time, with a record time resolution for x-ray probing of 55 fs. Second, in new work, we were able to probe the timescale of the exchange interaction in magnetic materials, also for the first time. Our measurements were made using the transverse magneto-optic Kerr effect (T-MOKE) geometry, since the reflectivity of a magnetic material changes with the direction of the magnetization vector of a surface. In our experiment, we periodically reversed the magnetization direction of a grating structure made of Permalloy (Ni80Fe20) using an external magnetic field. To achieve maximum contrast, we used HHG light spanning the M-shell (3p) absorption edges of Fe and Ni. Our characterization of the static magnetization of a Permalloy sample shows high magnetic asymmetry at photon energies just above and below the absorption edges at 55 eV and 65 eV, respectively. This result is in excellent agreement with measurements done on the same using a synchrotron source.

  9. Measuring dynamic kidney function in an undergraduate physiology laboratory.

    PubMed

    Medler, Scott; Harrington, Frederick

    2013-12-01

    Most undergraduate physiology laboratories are very limited in how they treat renal physiology. It is common to find teaching laboratories equipped with the capability for high-resolution digital recordings of physiological functions (muscle twitches, ECG, action potentials, respiratory responses, etc.), but most urinary laboratories still rely on a "dipstick" approach of urinalysis. Although this technique can provide some basic insights into the functioning of the kidneys, it overlooks the dynamic processes of filtration, reabsorption, and secretion. In the present article, we provide a straightforward approach of using renal clearance measurements to estimate glomerular filtration rate, fractional water reabsorption, glucose clearance, and other physiologically relevant parameters. The estimated values from our measurements in laboratory are in close agreement with those anticipated based on textbook parameters. For example, we found glomerular filtration rate to average 124 ± 45 ml/min, serum creatinine to be 1.23 ± 0.4 mg/dl, and fractional water reabsorption to be ∼96.8%. Furthermore, analyses for the class data revealed significant correlations between parameters like fractional water reabsorption and urine concentration, providing opportunities to discuss urine concentrating mechanisms and other physiological processes. The procedures outlined here are general enough that most undergraduate physiology laboratory courses should be able to implement them without difficulty.

  10. Measurement realities of current collection in dynamic space plasma environments

    NASA Technical Reports Server (NTRS)

    Szuszczewicz, Edward P.

    1990-01-01

    Theories which describe currents collected by conducting and non-conducting bodies immersed in plasmas have many of their concepts based upon the fundamentals of sheath-potential distributions and charged-particle behavior in superimposed electric and magnetic fields. Those current-collecting bodies (or electrodes) may be Langmuir probes, electric field detectors, aperture plates on ion mass spectrometers and retarding potential analyzers, or spacecraft and their rigid and tethered appendages. Often the models are incomplete in representing the conditions under which the current-voltage characteristics of the electrode and its system are to be measured. In such cases, the experimenter must carefully take into account magnetic field effects and particle anisotropies, perturbations caused by the current collection process itself and contamination on electrode surfaces, the complexities of non-Maxwellian plasma distributions, and the temporal variability of the local plasma density, temperature, composition and fields. This set of variables is by no means all-inclusive, but it represents a collection of circumstances guaranteed to accompany experiments involving energetic particle beams, plasma discharges, chemical releases, wave injection and various events of controlled and uncontrolled spacecraft charging. Here, an attempt is made to synopsize these diagnostic challenges and frame them within a perspective that focuses on the physics under investigation and the requirements on the parameters to be measured. Examples include laboratory and spaceborne applications, with specific interest in dynamic and unstable plasma environments.

  11. Measuring static and dynamic contact angles using a liquid needle

    NASA Astrophysics Data System (ADS)

    Sanedrin, Raymond; Jin, Ming; Frese, Daniel; Scheithauer, Carsten; Willers, Thomas

    2016-11-01

    The optical determination of static and advancing contact angle is made on drops applied or extended, respectively, onto a substrate through the use of thin solid needles. Although this method has been used extensively, this method of dosing can be time consuming, cumbersome and if not meticulously performed can lead to erroneous contact angle results. Herein, we present an alternative way of applying drops onto substrates using a small liquid jet, which is produced by a liquid pressure dosing system acting as a "liquid needle." A comparative static contact angle study on 14 different surfaces with two different liquids were performed utilizing two different ways of dosing: the conventional solid and a novel liquid needle based technique. We found, for all but one sample, that the obtained results were highly comparable. Observed differences can be explained by the characteristics of either way of dosing. In addition, we used the liquid pressure based dosing system for optical advancing contact angle measurement on two different samples. The liquid needle based method facilitates the expansion of a drop from 0.1 to 22 μL within less than 1.2 seconds, which provided constant contact angle versus drop base diameter curves. The obtained results were highly comparable with dynamic Wilhelmy contact angle measurements.

  12. Dynamical Mass Measurements of Contaminated Galaxy Clusters Using Machine Learning

    NASA Astrophysics Data System (ADS)

    Ntampaka, Michelle; Trac, Hy; Sutherland, Dougal; Fromenteau, Sebastien; Poczos, Barnabas; Schneider, Jeff

    2016-01-01

    Galaxy clusters are a rich source of information for examining fundamental astrophysical processes and cosmological parameters, however, employing clusters as cosmological probes requires accurate mass measurements derived from cluster observables. We study dynamical mass measurements of galaxy clusters contaminated by interlopers, and show that a modern machine learning (ML) algorithm can predict masses by better than a factor of two compared to a standard scaling relation approach. We create a mock catalog from Multidark's publicly-available N-body MDPL1 simulation where a simple cylindrical cut around the cluster center allows interlopers to contaminate the clusters. In the standard approach, we use a power law scaling relation to infer cluster mass from galaxy line of sight (LOS) velocity dispersion. The presence of interlopers in the catalog produces a wide, flat fractional mass error distribution, with width = 2.13. We employ the Support Distribution Machine (SDM) class of algorithms to learn from distributions of data to predict single values. Applied to distributions of galaxy observables such as LOS velocity and projected distance from the cluster center, SDM yields better than a factor-of-two improvement (width = 0.67). Remarkably, SDM applied to contaminated clusters is better able to recover masses than even a scaling relation approach applied to uncontaminated clusters. We show that the SDM method more accurately reproduces the cluster mass function, making it a valuable tool for employing cluster observations to evaluate cosmological models.

  13. Dynamic Associations of Change in Physical Activity and Change in Cognitive Function: Coordinated Analyses of Four Longitudinal Studies

    PubMed Central

    Lindwall, Magnus; Cimino, Cynthia R.; Gibbons, Laura E.; Mitchell, Meghan B.; Benitez, Andreana; Brown, Cassandra L.; Kennison, Robert F.; Shirk, Steven D.; Atri, Alireza; Robitaille, Annie; MacDonald, Stuart W. S.; Zelinski, Elizabeth M.; Willis, Sherry L.; Schaie, K. Warner; Johansson, Boo; Praetorius, Marcus; Dixon, Roger A.; Mungas, Dan M.; Hofer, Scott M.; Piccinin, Andrea M.

    2012-01-01

    The present study used a coordinated analyses approach to examine the association of physical activity and cognitive change in four longitudinal studies. A series of multilevel growth models with physical activity included both as a fixed (between-person) and time-varying (within-person) predictor of four domains of cognitive function (reasoning, memory, fluency, and semantic knowledge) was used. Baseline physical activity predicted fluency, reasoning and memory in two studies. However, there was a consistent pattern of positive relationships between time-specific changes in physical activity and time-specific changes in cognition, controlling for expected linear trajectories over time, across all four studies. This pattern was most evident for the domains of reasoning and fluency. PMID:23029615

  14. Control of high affinity interactions in the talin C terminus: how talin domains coordinate protein dynamics in cell adhesions.

    PubMed

    Himmel, Mirko; Ritter, Anett; Rothemund, Sven; Pauling, Björg V; Rottner, Klemens; Gingras, Alexandre R; Ziegler, Wolfgang H

    2009-05-15

    In cell-extracellular matrix junctions (focal adhesions), the cytoskeletal protein talin is central to the connection of integrins to the actin cytoskeleton. Talin is thought to mediate this connection via its two integrin, (at least) three actin, and several vinculin binding sites. The binding sites are cryptic in the head-to-rod autoinhibited cytoplasmic form of the protein and require (stepwise) conformational activation. This activation process, however, remains poorly understood, and there are contradictory models with respect to the determinants of adhesion site localization. Here, we report turnover rates and protein-protein interactions in a range of talin rod domain constructs varying in helix bundle structure. We conclude that several bundles of the C terminus cooperate to regulate targeting and concomitantly tailor high affinity interactions of the talin rod in cell adhesions. Intrinsic control of ligand binding activities is essential for the coordination of adhesion site function of talin.

  15. Poisson Coordinates.

    PubMed

    Li, Xian-Ying; Hu, Shi-Min

    2013-02-01

    Harmonic functions are the critical points of a Dirichlet energy functional, the linear projections of conformal maps. They play an important role in computer graphics, particularly for gradient-domain image processing and shape-preserving geometric computation. We propose Poisson coordinates, a novel transfinite interpolation scheme based on the Poisson integral formula, as a rapid way to estimate a harmonic function on a certain domain with desired boundary values. Poisson coordinates are an extension of the Mean Value coordinates (MVCs) which inherit their linear precision, smoothness, and kernel positivity. We give explicit formulas for Poisson coordinates in both continuous and 2D discrete forms. Superior to MVCs, Poisson coordinates are proved to be pseudoharmonic (i.e., they reproduce harmonic functions on n-dimensional balls). Our experimental results show that Poisson coordinates have lower Dirichlet energies than MVCs on a number of typical 2D domains (particularly convex domains). As well as presenting a formula, our approach provides useful insights for further studies on coordinates-based interpolation and fast estimation of harmonic functions.

  16. Dynamic Cross Talk Model of the Epithelial Innate Immune Response to Double-Stranded RNA Stimulation: Coordinated Dynamics Emerging from Cell-Level Noise

    PubMed Central

    Bertolusso, Roberto; Tian, Bing; Zhao, Yingxin; Vergara, Leoncio; Sabree, Aqeeb; Iwanaszko, Marta; Lipniacki, Tomasz; Brasier, Allan R.; Kimmel, Marek

    2014-01-01

    We present an integrated dynamical cross-talk model of the epithelial innate immune reponse (IIR) incorporating RIG-I and TLR3 as the two major pattern recognition receptors (PRR) converging on the RelA and IRF3 transcriptional effectors. bioPN simulations reproduce biologically relevant gene-and protein abundance measurements in response to time course, gene silencing and dose-response perturbations both at the population and single cell level. Our computational predictions suggest that RelA and IRF3 are under auto- and cross-regulation. We predict, and confirm experimentally, that RIG-I mRNA expression is controlled by IRF7. We also predict the existence of a TLR3-dependent, IRF3-independent transcription factor (or factors) that control(s) expression of MAVS, IRF3 and members of the IKK family. Our model confirms the observed dsRNA dose-dependence of oscillatory patterns in single cells, with periods of 1–3 hr. Model fitting to time series, matched by knockdown data suggests that the NF-κB module operates in a different regime (with different coefficient values) than in the TNFα-stimulation experiments. In future studies, this model will serve as a foundation for identification of virus-encoded IIR antagonists and examination of stochastic effects of viral replication. Our model generates simulated time series, which reproduce the noisy oscillatory patterns of activity (with 1–3 hour period) observed in individual cells. Our work supports the hypothesis that the IIR is a phenomenon that emerged by evolution despite highly variable responses at an individual cell level. PMID:24710104

  17. Noninvasive, quantitative respirator fit testing through dynamic pressure measurement.

    PubMed

    Carpenter, D R; Willeke, K

    1988-10-01

    A new method has been invented for the noninvasive and quantitative determination of fit for a respirator. The test takes a few seconds and requires less expensive instrumentation than presently used for invasive testing. In this test, the breath is held at a negative pressure for a few seconds, and the leak-induced pressure decay inside the respirator cavity is monitored. A dynamic pressure sensor is attached to a modified cartridge of an air-purifying respirator or built into the respirator body or into the air supply line of an air-supplied respirator. The method is noninvasive in that the modified cartridge can be mounted onto any air-purifying respirator. The pressure decay during testing quantifies the airflow entered through the leak site. An equation has been determined which gives the air leakage as a function of pressure decay slope, respirator volume and the pressure differential during actual wear--all of which are determined by the dynamic pressure sensor. Thus, the ratio of air inhaled through the filters or via the air supply line to the leak rate is a measure of respirator fit, independent of aerosol deposition in the lung and aerosol distribution in the respirator cavity as found for quantitative fit testing with aerosols. The new method is shown to be independent of leak and sensor locations. The concentration and distribution of aerosols entered through the leak site is dependent only on the physical dimensions of the leak site and the air velocity in it, which can be determined independently.(ABSTRACT TRUNCATED AT 250 WORDS)

  18. Dynamic range measurement and calibration of SiPMs

    NASA Astrophysics Data System (ADS)

    Bretz, T.; Hebbeker, T.; Lauscher, M.; Middendorf, L.; Niggemann, T.; Schumacher, J.; Stephan, M.; Bueno, A.; Navas, S.; Ruiz, A. G.

    2016-03-01

    Photosensors have played and will continue to play an important role in high-energy and Astroparticle cutting-edge experiments. As of today, the most common photon detection device in use is the photomultiplier tube (PMT). However, we are witnessing rapid progress in the field and new devices now show very competitive features when compared to PMTs. Among those state-of-the-art photo detectors, silicon photomultipliers (SiPMs) are a relatively new kind of semiconductor whose potential is presently studied by many laboratories. Their characteristics make them a very attractive candidate for future Astroparticle physics experiments recording fluorescence and Cherenkov light, both in the atmosphere and on the ground. Such applications may require the measurement of the light flux on the sensor for the purpose of energy reconstruction. This is a complex task due to the limited dynamic range of SiPMs and the presence of thermal and correlated noise. In this work we study the response of three SiPM types in terms of delivered charge when exposed to light pulses in a broad range of intensities: from single photon to saturation. The influence of the pulse time duration and the SiPM over-voltage on the response are also quantified. Based on the observed behaviour, a method is presented to reconstruct the real number of photons impinging on the SiPM surface directly from the measured SiPM charge. A special emphasis is placed on the description of the methodology and experimental design used to perform the measurements.

  19. A new method for dynamic performance improvement of a hybrid power system by coordination of converter's controller

    NASA Astrophysics Data System (ADS)

    Nayeripour, Majid; Hoseintabar, Mohammad; Niknam, Taher

    In this paper, a new strategy for modeling and controlling a hybrid power generation system that contains a fuel cell (FC) and super capacitor (SC) system is proposed. The main drawback of FC systems is its slow dynamic because the FC current slope must be limited in order to prevent fuel starvation problems and to improve its efficiency and lifetime. To overcome this slow dynamic and to improve dynamic performance, a new control strategy is proposed to combine FC system with SC system. The proposed control strategy can be also used for cold starting and different types of FC systems with different dynamics. The control strategy is capable of determining the desired FC power to prolong FC system lifetime and keeps the AC and DC voltages around its nominal value in transient event by supplying propulsion power and recuperating FC energy. The minimum SC system is computed in new method and used to meet the load demand to constraint the DC bus voltage and enhances power regulation under various active and reactive load conditions. Two different case studies are used to obtain the simulation results using MATLAB/SIMULINK to verify the validity of the proposed control strategy.

  20. Low cation coordination in oxide melts

    SciTech Connect

    Skinner, Lawrie; Benmore, Chris J; Du, Jincheng; Weber, Richard; Neuefeind, Joerg C; Tumber, Sonia; Parise, John B

    2014-01-01

    The complete set of Faber-Ziman partial pair distribution functions for a rare earth oxide liquid were measured for the first time by combining aerodynamic levitation, neutron diffraction, high energy x-ray diffraction and isomorphic substitution using Y2 O3 and Ho2 O3 melts. The average Y- O coordination is measured to be 5.5(2), which is significantly less than the octahedral coordination of crystalline Y2 O3 (or Ho2 O3 ). Investigation of high temperature La2 O3 , ZrO2 , SiO2 , and Al2 O3 melts by x-ray diffraction and molecular dynamics simulations also show lower-than-crystal cation- oxygen coordination. These measurements suggest a general trend towards lower M-O coordination compared to their crystalline counterparts. It is found that this coordination number drop is larger for lower field strength, larger radius cations and is negligible for high field strength (network forming) cations. These findings have broad implications for predicting the local structure and related physical properties of metal-oxide melts and oxide glasses.

  1. Action-perception coordination dynamics of whole-body rhythmic movement in stance: a comparison study of street dancers and non-dancers.

    PubMed

    Miura, Akito; Kudo, Kazutoshi; Nakazawa, Kimitaka

    2013-06-07

    This study investigated whether whole-body, rhythmic action-perception coordination in stance is organized in terms of dynamic principles. We observed whether phase transition and hysteresis occur during the execution of dancing movements. Nine skilled street dancers and 9 novice controls performed 2 types of rhythmic knee-bending movements to a metronome beat in the standing position. Participants performed down-on-the-beat (in which knee flexion coincides with the beat) and up-on-the-beat (in which knee extension coincides with the beat), which are both typical components of street dance. All participants were instructed not to intervene in the pattern change. The auditory stimulus beat rate increased or decreased between 60 and 220 beats per minute (bpm) in steps of 20 bpm. We calculated the phase angle of beat time that is superposed on knee movement trajectory on a phase plane. Under the up-on-the-beat condition, phase transition and hysteresis were observed. The bifurcation frequency at which phase transition occurred significantly differed between groups, indicating that dancers were able to perform up-on-the-beat at higher movement frequencies than non-dancers. This suggests that dynamical properties may differ between Dancers and Non-dancers. The present results provide additional evidence that whole-body action-perception pattern formation is governed by general and common dynamical principles.

  2. Coordinating Demand-Side Efficiency Evaluation, Measurement and Verification Among Western States: Options for Documenting Energy and Non-Energy Impacts for the Power Sector

    SciTech Connect

    Schiller, Steven R.; Schwartz, Lisa C.

    2016-06-22

    Demand-side energy efficiency (efficiency) represents a low-cost opportunity to reduce electricity consumption and demand and provide a wide range of non-energy benefits, including avoiding air pollution. Efficiency-related energy and non-energy impacts are determined and documented by implementing evaluation, measurement and verification (EM&V) systems. This technical brief describes efficiency EM&V coordination strategies that Western states can consider taking on together, outlines EM&V-related products that might be appropriate for multistate coordination, and identifies some implications of coordination. Coordinating efficiency EM&V activities can save both time and costs for state agencies and stakeholders engaged in efficiency activities and can be particularly beneficial for multiple states served by the same utility. First, the brief summarizes basic information on efficiency, its myriad potential benefits and EM&V for assessing those benefits. Second, the brief introduces the concept of multistate EM&V coordination in the context of assessing such benefits, including achievement of state and federal goals to reduce air pollutants.1 Next, the brief presents three coordination strategy options for efficiency EM&V: information clearinghouse/exchange, EM&V product development, and a regional energy efficiency tracking system platform. The brief then describes five regional EM&V products that could be developed on a multistate basis: EM&V reporting formats, database of consistent deemed electricity savings values, glossary of definitions and concepts, efficiency EM&V methodologies, and EM&V professional standards or accreditation processes. Finally, the brief discusses options for next steps that Western states can take to consider multistate coordination on efficiency EM&V. Appendices provide background information on efficiency and EM&V, as well as definitions and suggested resources on the covered topics. This brief is intended to inform state public

  3. Individual-Environment Interactions in Swimming: The Smallest Unit for Analysing the Emergence of Coordination Dynamics in Performance?

    PubMed

    Guignard, Brice; Rouard, Annie; Chollet, Didier; Hart, John; Davids, Keith; Seifert, Ludovic

    2017-02-08

    Displacement in competitive swimming is highly dependent on fluid characteristics, since athletes use these properties to propel themselves. It is essential for sport scientists and practitioners to clearly identify the interactions that emerge between each individual swimmer and properties of an aquatic environment. Traditionally, the two protagonists in these interactions have been studied separately. Determining the impact of each swimmer's movements on fluid flow, and vice versa, is a major challenge. Classic biomechanical research approaches have focused on swimmers' actions, decomposing stroke characteristics for analysis, without exploring perturbations to fluid flows. Conversely, fluid mechanics research has sought to record fluid behaviours, isolated from the constraints of competitive swimming environments (e.g. analyses in two-dimensions, fluid flows passively studied on mannequins or robot effectors). With improvements in technology, however, recent investigations have focused on the emergent circular couplings between swimmers' movements and fluid dynamics. Here, we provide insights into concepts and tools that can explain these on-going dynamic interactions in competitive swimming within the theoretical framework of ecological dynamics.

  4. Measurement of human pilot dynamic characteristics in flight simulation

    NASA Technical Reports Server (NTRS)

    Reedy, James T.

    1987-01-01

    Fast Fourier Transform (FFT) and Least Square Error (LSE) estimation techniques were applied to the problem of identifying pilot-vehicle dynamic characteristics in flight simulation. A brief investigation of the effects of noise, input bandwidth and system delay upon the FFT and LSE techniques was undertaken using synthetic data. Data from a piloted simulation conducted at NASA Ames Research Center was then analyzed. The simulation was performed in the NASA Ames Research Center Variable Stability CH-47B helicopter operating in fixed-basis simulator mode. The piloting task consisted of maintaining the simulated vehicle over a moving hover pad whose motion was described by a random-appearing sum of sinusoids. The two test subjects used a head-down, color cathode ray tube (CRT) display for guidance and control information. Test configurations differed in the number of axes being controlled by the pilot (longitudinal only versus longitudinal and lateral), and in the presence or absence of an important display indicator called an 'acceleration ball'. A number of different pilot-vehicle transfer functions were measured, and where appropriate, qualitatively compared with theoretical pilot- vehicle models. Some indirect evidence suggesting pursuit behavior on the part of the test subjects is discussed.

  5. Force measurement enabling precise analysis by dynamic force spectroscopy.

    PubMed

    Taninaka, Atsushi; Hirano, Yuuichi; Takeuchi, Osamu; Shigekawa, Hidemi

    2012-01-01

    Dynamic force spectroscopy (DFS) makes it possible to investigate specific interactions between two molecules such as ligand-receptor pairs at the single-molecule level. In the DFS method based on the Bell-Evans model, the unbinding force applied to a molecular bond is increased at a constant rate, and the force required to rupture the molecular bond is measured. By analyzing the relationship between the modal rupture force and the logarithm of the loading rate, microscopic potential barrier landscapes and the lifetimes of bonds can be obtained. However, the results obtained, for example, in the case of streptavidin/biotin complexes, have differed among previous studies and some results have been inconsistent with theoretical predictions. In this study, using an atomic force microscopy technique that enables the precise analysis of molecular interactions on the basis of DFS, we investigated the effect of the sampling rate on DFS analysis. The shape of rupture force histograms, for example, was significantly deformed at a sampling rate of 1 kHz in comparison with that of histograms obtained at 100 kHz, indicating the fundamental importance of ensuring suitable experimental conditions for further advances in the DFS method.

  6. Testing and Validation of the Dynamic Inertia Measurement Method

    NASA Technical Reports Server (NTRS)

    Chin, Alexander W.; Herrera, Claudia Y.; Spivey, Natalie D.; Fladung, William A.; Cloutier, David

    2015-01-01

    The Dynamic Inertia Measurement (DIM) method uses a ground vibration test setup to determine the mass properties of an object using information from frequency response functions. Most conventional mass properties testing involves using spin tables or pendulum-based swing tests, which for large aerospace vehicles becomes increasingly difficult and time-consuming, and therefore expensive, to perform. The DIM method has been validated on small test articles but has not been successfully proven on large aerospace vehicles. In response, the National Aeronautics and Space Administration Armstrong Flight Research Center (Edwards, California) conducted mass properties testing on an "iron bird" test article that is comparable in mass and scale to a fighter-type aircraft. The simple two-I-beam design of the "iron bird" was selected to ensure accurate analytical mass properties. Traditional swing testing was also performed to compare the level of effort, amount of resources, and quality of data with the DIM method. The DIM test showed favorable results for the center of gravity and moments of inertia; however, the products of inertia showed disagreement with analytical predictions.

  7. High Temperature Dynamic Pressure Measurements Using Silicon Carbide Pressure Sensors

    NASA Technical Reports Server (NTRS)

    Okojie, Robert S.; Meredith, Roger D.; Chang, Clarence T.; Savrun, Ender

    2014-01-01

    Un-cooled, MEMS-based silicon carbide (SiC) static pressure sensors were used for the first time to measure pressure perturbations at temperatures as high as 600 C during laboratory characterization, and subsequently evaluated in a combustor rig operated under various engine conditions to extract the frequencies that are associated with thermoacoustic instabilities. One SiC sensor was placed directly in the flow stream of the combustor rig while a benchmark commercial water-cooled piezoceramic dynamic pressure transducer was co-located axially but kept some distance away from the hot flow stream. In the combustor rig test, the SiC sensor detected thermoacoustic instabilities across a range of engine operating conditions, amplitude magnitude as low as 0.5 psi at 585 C, in good agreement with the benchmark piezoceramic sensor. The SiC sensor experienced low signal to noise ratio at higher temperature, primarily due to the fact that it was a static sensor with low sensitivity.

  8. Dynamical Mass Measurements of Contaminated Galaxy Clusters Using Machine Learning

    NASA Astrophysics Data System (ADS)

    Ntampaka, M.; Trac, H.; Sutherland, D. J.; Fromenteau, S.; Póczos, B.; Schneider, J.

    2016-11-01

    We study dynamical mass measurements of galaxy clusters contaminated by interlopers and show that a modern machine learning algorithm can predict masses by better than a factor of two compared to a standard scaling relation approach. We create two mock catalogs from Multidark’s publicly available N-body MDPL1 simulation, one with perfect galaxy cluster membership information and the other where a simple cylindrical cut around the cluster center allows interlopers to contaminate the clusters. In the standard approach, we use a power-law scaling relation to infer cluster mass from galaxy line-of-sight (LOS) velocity dispersion. Assuming perfect membership knowledge, this unrealistic case produces a wide fractional mass error distribution, with a width of {{Δ }}ε ≈ 0.87. Interlopers introduce additional scatter, significantly widening the error distribution further ({{Δ }}ε ≈ 2.13). We employ the support distribution machine (SDM) class of algorithms to learn from distributions of data to predict single values. Applied to distributions of galaxy observables such as LOS velocity and projected distance from the cluster center, SDM yields better than a factor-of-two improvement ({{Δ }}ε ≈ 0.67) for the contaminated case. Remarkably, SDM applied to contaminated clusters is better able to recover masses than even the scaling relation approach applied to uncontaminated clusters. We show that the SDM method more accurately reproduces the cluster mass function, making it a valuable tool for employing cluster observations to evaluate cosmological models.

  9. Measurements of turbulent premixed flame dynamics using cinema stereoscopic PIV

    NASA Astrophysics Data System (ADS)

    Steinberg, Adam M.; Driscoll, James F.; Ceccio, Steven L.

    2008-06-01

    A new experimental method is described that provides high-speed movies of turbulent premixed flame wrinkling dynamics and the associated vorticity fields. This method employs cinema stereoscopic particle image velocimetry and has been applied to a turbulent slot Bunsen flame. Three-component velocity fields were measured with high temporal and spatial resolutions of 0.9 ms and 140 μm, respectively. The flame-front location was determined using a new multi-step method based on particle image gradients, which is described. Comparisons are made between flame fronts found with this method and simultaneous CH-PLIF images. These show that the flame contour determined corresponds well to the true location of maximum gas density gradient. Time histories of typical eddy-flame interactions are reported and several important phenomena identified. Outwardly rotating eddy pairs wrinkle the flame and are attenuated at they pass through the flamelet. Significant flame-generated vorticity is produced downstream of the wrinkled tip. Similar wrinkles are caused by larger groups of outwardly rotating eddies. Inwardly rotating pairs cause significant convex wrinkles that grow as the flame propagates. These wrinkles encounter other eddies that alter their behavior. The effects of the hydrodynamic and diffusive instabilities are observed and found to be significant contributors to the formation and propagation of wrinkles.

  10. Circadian dynamics in measures of cortical excitation and inhibition balance

    PubMed Central

    Chellappa, Sarah L.; Gaggioni, Giulia; Ly, Julien Q. M.; Papachilleos, Soterios; Borsu, Chloé; Brzozowski, Alexandre; Rosanova, Mario; Sarasso, Simone; Luxen, André; Middleton, Benita; Archer, Simon N.; Dijk, Derk-Jan; Massimini, Marcello; Maquet, Pierre; Phillips, Christophe; Moran, Rosalyn J.; Vandewalle, Gilles

    2016-01-01

    Several neuropsychiatric and neurological disorders have recently been characterized as dysfunctions arising from a ‘final common pathway’ of imbalanced excitation to inhibition within cortical networks. How the regulation of a cortical E/I ratio is affected by sleep and the circadian rhythm however, remains to be established. Here we addressed this issue through the analyses of TMS-evoked responses recorded over a 29 h sleep deprivation protocol conducted in young and healthy volunteers. Spectral analyses of TMS-evoked responses in frontal cortex revealed non-linear changes in gamma band evoked oscillations, compatible with an influence of circadian timing on inhibitory interneuron activity. In silico inferences of cell-to-cell excitatory and inhibitory connectivity and GABA/Glutamate receptor time constant based on neural mass modeling within the Dynamic causal modeling framework, further suggested excitation/inhibition balance was under a strong circadian influence. These results indicate that circadian changes in EEG spectral properties, in measure of excitatory/inhibitory connectivity and in GABA/glutamate receptor function could support the maintenance of cognitive performance during a normal waking day, but also during overnight wakefulness. More generally, these findings demonstrate a slow daily regulation of cortical excitation/inhibition balance, which depends on circadian-timing and prior sleep-wake history. PMID:27651114

  11. Implosion dynamics measurements at the National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Hicks, D. G.; Meezan, N. B.; Dewald, E. L.; Mackinnon, A. J.; Olson, R. E.; Callahan, D. A.; Döppner, T.; Benedetti, L. R.; Bradley, D. K.; Celliers, P. M.; Clark, D. S.; Di Nicola, P.; Dixit, S. N.; Dzenitis, E. G.; Eggert, J. E.; Farley, D. R.; Frenje, J. A.; Glenn, S. M.; Glenzer, S. H.; Hamza, A. V.; Heeter, R. F.; Holder, J. P.; Izumi, N.; Kalantar, D. H.; Khan, S. F.; Kline, J. L.; Kroll, J. J.; Kyrala, G. A.; Ma, T.; MacPhee, A. G.; McNaney, J. M.; Moody, J. D.; Moran, M. J.; Nathan, B. R.; Nikroo, A.; Opachich, Y. P.; Petrasso, R. D.; Prasad, R. R.; Ralph, J. E.; Robey, H. F.; Rinderknecht, H. G.; Rygg, J. R.; Salmonson, J. D.; Schneider, M. B.; Simanovskaia, N.; Spears, B. K.; Tommasini, R.; Widmann, K.; Zylstra, A. B.; Collins, G. W.; Landen, O. L.; Kilkenny, J. D.; Hsing, W. W.; MacGowan, B. J.; Atherton, L. J.; Edwards, M. J.

    2012-12-01

    Measurements have been made of the in-flight dynamics of imploding capsules indirectly driven by laser energies of 1-1.7 MJ at the National Ignition Facility [Miller et al., Nucl. Fusion 44, 228 (2004)]. These experiments were part of the National Ignition Campaign [Landen et al., Phys. Plasmas 18, 051002 (2011)] to iteratively optimize the inputs required to achieve thermonuclear ignition in the laboratory. Using gated or streaked hard x-ray radiography, a suite of ablator performance parameters, including the time-resolved radius, velocity, mass, and thickness, have been determined throughout the acceleration history of surrogate gas-filled implosions. These measurements have been used to establish a dynamically consistent model of the ablative drive history and shell compressibility throughout the implosion trajectory. First results showed that the peak velocity of the original 1.3-MJ Ge-doped polymer (CH) point design using Au hohlraums reached only 75% of the required ignition velocity. Several capsule, hohlraum, and laser pulse changes were then implemented to improve this and other aspects of implosion performance and a dedicated effort was undertaken to test the sensitivity of the ablative drive to the rise time and length of the main laser pulse. Changing to Si rather than Ge-doped inner ablator layers and increasing the pulse length together raised peak velocity to 93% ± 5% of the ignition goal using a 1.5 MJ, 420 TW pulse. Further lengthening the pulse so that the laser remained on until the capsule reached 30% (rather than 60%-70%) of its initial radius, reduced the shell thickness and improved the final fuel ρR on companion shots with a cryogenic hydrogen fuel layer. Improved drive efficiency was observed using U rather than Au hohlraums, which was expected, and by slowing the rise time of laser pulse, which was not. The effect of changing the Si-dopant concentration and distribution, as well as the effect of using a larger initial shell thickness

  12. Hawking Radiation of Dirac Particles from a General Dynamical Spherically Symmetrical Black Hole Using a New Tortoise Coordinate Transformation

    NASA Astrophysics Data System (ADS)

    Liang, Jun; Zhang, Fang-Hui; Zhang, Wei; Zhang, Jing

    2014-01-01

    By utilizing the improved Damour-Ruffini method with a new tortoise transformation, we study the Hawking radiation of Dirac particles from a general dynamical spherically symmetric black hole. In the improved Damour-Ruffini method, the position of the event horizon of the black hole is an undetermined function, and the temperature parameter κ is an undetermined constant. By requiring the Dirac equation to be the standard wave equation near the event horizon of the black hole, κ can be determined automatically. Therefore, the Hawking temperature can be obtained. The result is consistent with that of the Hawking radiation of scalar particles.

  13. Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.

    PubMed

    Miyoshi, Goichi; Fishell, Gord

    2012-06-21

    Pyramidal cells of the cerebral cortex are born in the ventricular zone and migrate through the intermediate zone to enter into the cortical plate. In the intermediate zone, these migrating precursors move tangentially and initiate the extension of their axons by transiently adopting a characteristic multipolar morphology. We observe that expression of the forkhead transcription factor FoxG1 is dynamically regulated during this transitional period. By utilizing conditional genetic strategies, we show that the downregulation of FoxG1 at the beginning of the multipolar cell phase induces Unc5D expression, the timing of which ultimately determines the laminar identity of pyramidal neurons. In addition, we demonstrate that the re-expression of FoxG1 is required for cells to transit out of the multipolar cell phase and to enter into the cortical plate. Thus, the dynamic expression of FoxG1 during migration within the intermediate zone is essential for the proper assembly of the cerebral cortex.

  14. Flash-and-Freeze: Coordinating Optogenetic Stimulation with Rapid Freezing to Visualize Membrane Dynamics at Synapses with Millisecond Resolution

    PubMed Central

    Watanabe, Shigeki

    2016-01-01

    Electron microscopy depicts subcellular structures at synapses exquisitely but only captures static images. To visualize membrane dynamics, we have developed a novel technique, called flash-and-freeze, which induces neuronal activity with a flash of light and captures the membrane dynamics by rapid freezing. For characterizing membrane movements during synaptic transmission, a light-sensitive cation channel, channelrhodopsin, is heterologously expressed in mouse hippocampal neurons or in Caenorhabditis elegans motor neurons. A brief pulse of blue light activates channelrhodopsin and induces an action potential, leading to synaptic transmission. Following the light stimulation, neurons are frozen at different time intervals ranging from 10 ms to 20 s. Electron micrographs are then acquired from each time point to visualize the morphological changes. Using this approach, we have characterized a novel form of endocytosis, ultrafast endocytosis, which rapidly removes excess membrane added to the surface during neurotransmission. The flash-and-freeze approach can be adapted to study other cellular phenomena that can be induced by light-sensitive genetic or pharmacological tools. PMID:27594835

  15. Magnetic properties of weakly exchange-coupled high spin Co(II) ions in pseudooctahedral coordination evaluated by single crystal X-band EPR spectroscopy and magnetic measurements.

    PubMed

    Neuman, Nicolás I; Winkler, Elín; Peña, Octavio; Passeggi, Mario C G; Rizzi, Alberto C; Brondino, Carlos D

    2014-03-03

    We report single-crystal X-band EPR and magnetic measurements of the coordination polymer catena-(trans-(μ2-fumarato)tetraaquacobalt(II)), 1, and the Co(II)-doped Zn(II) analogue, 2, in different Zn:Co ratios. 1 presents two magnetically inequivalent high spin S = 3/2 Co(II) ions per unit cell, named A and B, in a distorted octahedral environment coordinated to four water oxygen atoms and trans coordinated to two carboxylic oxygen atoms from the fumarate anions, in which the Co(II) ions are linked by hydrogen bonds and fumarate molecules. Magnetic susceptibility and magnetization measurements of 1 indicate weak antiferromagnetic exchange interactions between the S = 3/2 spins of the Co(II) ions in the crystal lattice. Oriented single crystal EPR experiments of 1 and 2 were used to evaluate the molecular g-tensor and the different exchange coupling constants between the Co(II) ions, assuming an effective spin S′= 1/2. Unexpectedly, the eigenvectors of the molecular g-tensor were not lying along any preferential bond direction, indicating that, in high spin Co(II) ions in roughly octahedral geometry with approximately axial EPR signals, the presence of molecular pseudo axes in the metal site does not determine preferential directions for the molecular g-tensor. The EPR experiment and magnetic measurements, together with a theoretical analysis relating the coupling constants obtained from both techniques, allowed us to evaluate selectively the exchange coupling constant associated with hydrogen bonds that connect magnetically inequivalent Co(II) ions (|JAB(1/2)| = 0.055(2) cm(–1)) and the exchange coupling constant associated with a fumarate bridge connecting equivalent Co(II) ions (|JAA(1/2)| ≈ 0.25 (1) cm(–1)), in good agreement with the average J(3/2) value determined from magnetic measurements.

  16. Measured Two-Dimensional Ice-Wedge Polygon Thermal Dynamics

    NASA Astrophysics Data System (ADS)

    Cable, William; Romanovsky, Vladimir; Busey, Robert

    2016-04-01

    Ice-wedge polygons are perhaps the most dominant permafrost related features in the arctic landscape. The microtopography of these features, that includes rims, troughs, and high and low polygon centers, alters the local hydrology, as water tends to collect in the low areas. During winter, wind redistribution of snow leads to an increased snowpack depth in the low areas, while the slightly higher areas often have very thin snow cover, leading to differences across the landscape in vegetation communities and soil moisture between higher and lower areas. These differences in local surface conditions lead to spatial variability of the ground thermal regime in the different microtopographic areas and between different types of ice-wedge polygons. To study these features in depth, we established temperature transects across four different types of ice-wedge polygons near Barrow, Alaska. The transects were composed of five vertical array thermistor probes (VATP) beginning in the center of each polygon and extending through the trough to the rim of the adjacent polygon. Each VATP had 16 thermistors from the surface to a depth of 1.5 m. In addition to these 80 subsurface temperature measurement points per polygon, soil moisture, thermal conductivity, heat flux, and snow depth were all measured in multiple locations for each polygon. Above ground, a full suite of micrometeorological instrumentation was present at each polygon. Data from these sites has been collected continuously for the last three years. We found snow cover, timing and depth, and active layer soil moisture to be major controlling factors in the observed thermal regimes. In troughs and in the centers of low-center polygons, the combined effect of typically saturated soils and increased snow accumulation resulted in the highest mean annual ground temperatures (MAGT). Additionally, these areas were the last part of the polygon to refreeze during the winter. However, increased active layer thickness was not

  17. CSF clearance in Alzheimer Disease measured with dynamic PET.

    PubMed

    de Leon, Mony J; Li, Yi; Okamura, Nobuyuki; Tsui, Wai H; Saint Louis, Les A; Glodzik, Lidia; Osorio, Ricardo S; Fortea, Juan; Butler, Tracy; Pirraglia, Elizabeth; Fossati, Silvia; Kim, Hee-Jin; Carare, Roxana O; Nedergaard, Maiken; Benveniste, Helene; Rusinek, Henry

    2017-03-16

    Evidence supporting the hypothesis that reduced cerebrospinal fluid (CSF) clearance is involved in the pathophysiology of Alzheimer's disease (AD) comes from primarily from rodent models. However, unlike rodents where predominant extra-cranial CSF egress is via olfactory nerves traversing the cribriform plate, human CSF clearance pathways are not well characterized. Using dynamic Positron Emission Tomography (PET) with (18)F-THK5117 a tracer for tau pathology, the ventricular CSF time activity was used as a biomarker for CSF clearance. We tested three hypotheses: 1. Extra-cranial CSF is detected at the superior turbinates; 2. CSF clearance is reduced in AD; and 3. CSF clearance is inversely associated with amyloid deposition. Methods: 15 subjects, 8 with AD and 7 normal control volunteers were examined with (18)F-THK5117. 10 subjects additionally received (11)C-PiB PET scans and 8 were PiB positive. Ventricular time activity curves (TAC) of (18)F-THK5117 were used to identify highly correlated TAC from extra-cranial voxels. Results: For all subjects, the greatest density of CSF positive extra-cranial voxels was in the nasal turbinates. Tracer concentration analyses validated the superior nasal turbinate CSF signal intensity. AD patients showed ventricular tracer clearance reduced by 23% and 66% fewer superior turbinate CSF egress sites. Ventricular CSF clearance was inversely associated with amyloid deposition. Conclusion: The human nasal turbinate is part of the CSF clearance system. Lateral ventricle and superior nasal turbinates CSF clearance abnormalities are found in AD. Ventricular CSF clearance reductions are associated with increased brain amyloid depositions. These data suggest that PET measured CSF clearance is a biomarker of potential interest in AD and other neurodegenerative diseases.

  18. Invariant Measures for Dissipative Dynamical Systems: Abstract Results and Applications

    NASA Astrophysics Data System (ADS)

    Chekroun, Mickaël D.; Glatt-Holtz, Nathan E.

    2012-12-01

    In this work we study certain invariant measures that can be associated to the time averaged observation of a broad class of dissipative semigroups via the notion of a generalized Banach limit. Consider an arbitrary complete separable metric space X which is acted on by any continuous semigroup { S( t)} t ≥ 0. Suppose that { S( t)} t ≥ 0 possesses a global attractor {{A}}. We show that, for any generalized Banach limit LIM T → ∞ and any probability distribution of initial conditions {{m}_0}, that there exists an invariant probability measure {{m}}, whose support is contained in {{A}}, such that intX \\varphi(x) d{m}(x) = \\underset{t rightarrow infty}LIM1/T int_0^T int_X \\varphi(S(t) x) d{m}_0(x) dt, for all observables φ living in a suitable function space of continuous mappings on X. This work is based on the framework of Foias et al. (Encyclopedia of mathematics and its applications, vol 83. Cambridge University Press, Cambridge, 2001); it generalizes and simplifies the proofs of more recent works (Wang in Disc Cont Dyn Syst 23(1-2):521-540, 2009; Lukaszewicz et al. in J Dyn Diff Eq 23(2):225-250, 2011). In particular our results rely on the novel use of a general but elementary topological observation, valid in any metric space, which concerns the growth of continuous functions in the neighborhood of compact sets. In the case when { S( t)} t ≥ 0 does not possess a compact absorbing set, this lemma allows us to sidestep the use of weak compactness arguments which require the imposition of cumbersome weak continuity conditions and thus restricts the phase space X to the case of a reflexive Banach space. Two examples of concrete dynamical systems where the semigroup is known to be non-compact are examined in detail. We first consider the Navier-Stokes equations with memory in the diffusion terms. This is the so called Jeffery's model which describes certain classes of viscoelastic fluids. We then consider a family of neutral delay differential

  19. Inhibitory synapse dynamics: coordinated presynaptic and postsynaptic mobility and the major contribution of recycled vesicles to new synapse formation.

    PubMed

    Dobie, Frederick A; Craig, Ann Marie

    2011-07-20

    Dynamics of GABAergic synaptic components have been studied previously over milliseconds to minutes, revealing mobility of postsynaptic scaffolds and receptors. Here we image inhibitory synapses containing fluorescently tagged postsynaptic scaffold Gephyrin, together with presynaptic vesicular GABA transporter (VGAT) or postsynaptic GABA(A) receptor γ2 subunit (GABA(A)Rγ2), over seconds to days in cultured rat hippocampal neurons, revealing modes of inhibitory synapse formation and remodeling. Entire synapses were mobile, translocating rapidly within a confined region and exhibiting greater nonstochastic motion over multihour periods. Presynaptic and postsynaptic components moved in unison, maintaining close apposition while translocating distances of several micrometers. An observed flux in the density of synaptic puncta partially resulted from the apparent merging and splitting of preexisting clusters. De novo formation of inhibitory synapses was observed, marked by the appearance of stably apposed Gephyrin and VGAT clusters at sites previously lacking either component. Coclustering of GABA(A)Rγ2 supports the identification of such new clusters as synapses. Nascent synapse formation occurred by gradual accumulation of components over several hours, with VGAT clustering preceding that of Gephyrin and GABA(A)Rγ2. Comparing VGAT labeling by active uptake of a luminal domain antibody with post hoc immunocytochemistry indicated that recycling vesicles from preexisting boutons significantly contribute to vesicle pools at the majority of new inhibitory synapses. Although new synapses formed primarily on dendrite shafts, some also formed on dendritic protrusions, without apparent interconversion. Altogether, the long-term imaging of GABAergic presynaptic and postsynaptic components reveals complex dynamics and perpetual remodeling with implications for mechanisms of assembly and synaptic integration.

  20. Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2- and 3-dimensional environments.

    PubMed

    Kim, Hye-Jin; Kwon, Sojung; Nam, Seo Hee; Jung, Jae Woo; Kang, Minkyung; Ryu, Jihye; Kim, Ji Eon; Cheong, Jin-Gyu; Cho, Chang Yun; Kim, Somi; Song, Dae-Geun; Kim, Yong-Nyun; Kim, Tai Young; Jung, Min-Kyo; Lee, Kyung-Min; Pack, Chan-Gi; Lee, Jung Weon

    2017-04-01

    Membrane proteins sense extracellular cues and transduce intracellular signaling to coordinate directionality and speed during cellular migration. They are often localized to specific regions, as with lipid rafts or tetraspanin-enriched microdomains; however, the dynamic interactions of tetraspanins with diverse receptors within tetraspanin-enriched microdomains on cellular surfaces remain largely unexplored. Here, we investigated effects of tetraspan(in) TM4SF5 (transmembrane 4 L6 family member 5)-enriched microdomains (T5ERMs) on the directionality of cell migration. Physical association of TM4SF5 with epidermal growth factor receptor (EGFR) and integrin α5 was visualized by live fluorescence cross-correlation spectroscopy and higher-resolution microscopy at the leading edge of migratory cells, presumably forming TM4SF5-enriched microdomains. Whereas TM4SF5 and EGFR colocalized at the migrating leading region more than at the rear, TM4SF5 and integrin α5 colocalized evenly throughout cells. Cholesterol depletion and disruption in TM4SF5 post-translational modifications, including N-glycosylation and palmitoylation, altered TM4SF5 interactions and cellular localization, which led to less cellular migration speed and directionality in 2- or 3-dimensional conditions. TM4SF5 controlled directional cell migration and invasion, and importantly, these TM4SF5 functions were dependent on cholesterol, TM4SF5 post-translational modifications, and EGFR and integrin α5 activity. Altogether, we showed that TM4SF5 dynamically interacted with EGFR and integrin α5 in migratory cells to control directionality and invasion.-Kim, H.-J., Kwon, S., Nam, S. H., Jung, J. W., Kang, M., Ryu, J., Kim, J. E., Cheong, J.-G., Cho, C. Y., Kim, S., Song, D.-G., Kim, Y.-N., Kim, T. Y., Jung, M.-K., Lee, K.-M., Pack, C.-G., Lee, J. W. Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2- and 3-dimensional environments.

  1. Estimates of Continental Plate Motions Derived From Continuous GPS Measurements of Station Coordinates and Velocities, 1996-2004

    NASA Astrophysics Data System (ADS)

    Hutchison, D. A.

    2004-05-01

    Analysis Centres of the International GPS Service (IGS) currently compute daily Earth Rotation Parameters (ERPs) and weekly precise coordinates for over 200 globally distributed tracking stations. These estimates are made available to the scientific community in the Solution Independent Exchange (SINEX) format, developed for exchange and analysis of position estimates from techniques such as SLR, LLR, VLBI, DORIS and GPS. On behalf of the IGS, National Resources Canada (NRCan) has been combining, officially since 1999, all weekly SINEX files from the ACs to form weekly and cumulative solutions. The weekly solution (named igsyyPwwww, yy = 2-digit year, wwww = 4-digit GPS week) contains estimates of station coordinates, ERPs and geocentre pertaining to the GPS week, and the cumulative solution (named IGSyyPWW, WW = 2-digit week number, 01 to 52, within the year) comprises station coordinates and velocities in a common reference epoch, Jan. 1, 1998. For example, two solutions produced for week 1253 (2nd week of year 2004) were igs04P1253 (weekly) and IGS04P02 (cumulative). Since week 1253, all IGS solutions have been aligned to IGb00, a realization of IGS's most recent International Terrestrial Reference Frame, ITRF2000. IGb00 was obtained from coordinates and velocities of 99 globally distributed reference stations by alignment to ITRF2000 at GPS week 1231 of cumulative solution IGS03P33. Before week 1143, a realization of IGS's previous reference frame, ITRF97, was used instead. Using the cumulative solution from any given week, the rotation components of any continental plate with at least two stations are estimated and compared with published results. These include three known plate models: NNR NUVEL 1, NNR NUVEL 1A and the most recent REVEL 2000 aligned to ITRF97. The findings can be summarized as follows: Continental rotations derived from IGS04P02 are shown to be significantly different at 99% confidence level from NNR NUVEL 1A's estimates for North American

  2. Acquisition and Retention of Team Coordination in Command-and-Control

    DTIC Science & Technology

    2007-07-01

    were used to describe the dynamics of actively stabilizing an inherently unstable system. In particular the Hurst exponent (H) is often measured via...team coordination dynamics were calculated across the coordination score trial series. These included the Hurst exponents (short and long region...Retention Interval ANOVA was conducted separately on Hurst short region, Hurst long region, and Lyapunov exponents . In addition a Levene test for

  3. Dynamic Measures of Elastic Nonlinear (Anelastic) Behavior: Dynamic Acousto-Elasticity Testing (DAET)

    NASA Astrophysics Data System (ADS)

    Renaud, G.; Le Bas, P.; Ten Cate, J. A.; Ulrich, T. J.; Carey, J. W.; Han, J.; Darling, T. W.; Johnson, P. A.

    2011-12-01

    Unraveling the physics of the earthquake source, reliable sequestration of CO2, predicting wellbore breakout in oil and gas reservoirs, monitoring thermal damage to rock in nuclear waste storage, and probing cement integrity require new approaches to material characterization and imaging. The elastic nonlinear material response is extremely promising in this regard. A persistent problem has been the direct relation between elastic nonlinearity and mechanical damage, because a reliable physics-based theory does not yet exist; however, recent work in medical nonlinear acoustics has led to an experimental breakthrough in measuring material nonlinear response. The breakthrough, termed Dynamic Acousto-Elasticity Testing (e.g., Renaud et al, 2008), has significant implication to development of a physics based theory, and thus ultimately to our ability to directly relate nonlinear material behavior to damage. The method provides the means to dynamically study the velocity-pressure and attenuation-pressure behaviors through the full wave cycle in contrast to most methods that measure average response (e.g., Nonlinear Resonance Ultrasound Spectroscopy [e.g., Guyer and Johnson, 2009]). The method relies on exciting a sample with a low frequency vibration in order to cycle it through stress-strain multiple times. Simultaneously, a high frequency ultrasonic source applies pulses and the change in wavespeed as a function of the low frequency stress is measured. In crystalline rock, we expect that the elastic nonlinearity arises from the microcracks and dislocations contained within individual crystals. In contrast, sandstones, limestones and other sedimentary rocks may have other origin(s) of elastic nonlinearity that are currently under debate. Thus we can use a crystalline sample as a point of reference from which to extrapolate to other sources of nonlinear mechanisms. We report results from our preliminary studies applying a number of room-dry rock samples of differing rock

  4. Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stability

    PubMed Central

    Park, Mi Hee; Choi, Kang-Yell; Jung, Yunjin; Min, Do Sik

    2014-01-01

    Hypoxia-inducible factor-1α (HIF-1α) is a master transcriptional regulator of cellular response to hypoxia. In normoxia, HIF-1α is degraded through the prolyl hydroxylase (PHD) and von Hippel-Lindau (VHL) ubiquitination pathway. However, it is unknown whether PHD and VHL exert their enzymatic activities on HIF-1α separately or as a multiprotein complex. Here, we show that phospholipase D1 (PLD1) protein itself acts as a molecular platform, interacting directly with HIF-1α, PHD, and VHL, thereby dynamically assembling a multiprotein complex that mediates efficient degradation of HIF-1α in an O2-dependent manner. PLD1 depletion prevents degradation of HIF-1α; however, overall, PLD1 activity is predominantly involved in the upregulation of HIF-1α through increased translation, despite negative regulation of HIF-1α stability by PLD1 protein itself, suggesting dual roles of PLD1 in the regulation of HIF-1α. Disruption of the interactions of PLD1 with the proteins might be involved in hypoxic stabilization of HIF-1α. Interestingly, the pleckstrin homology domain interacting with these proteins promoted degradation of HIF-1α independent of oxygen concentration and suppressed tumor progression. These observations define a novel function of PLD1 as a previously unrecognized HIF-1α regulator. PMID:25361009

  5. A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face.

    PubMed

    Hu, Diane; Young, Nathan M; Li, Xin; Xu, Yanhua; Hallgrímsson, Benedikt; Marcucio, Ralph S

    2015-02-01

    The mechanisms of morphogenesis are not well understood, yet shaping structures during development is essential for establishing correct organismal form and function. Here, we examine mechanisms that help to shape the developing face during the crucial period of facial primordia fusion. This period of development is a time when the faces of amniote embryos exhibit the greatest degree of similarity, and it probably results from the necessity for fusion to occur to establish the primary palate. Our results show that hierarchical induction mechanisms, consisting of iterative signaling by Sonic hedgehog (SHH) followed by Bone morphogenetic proteins (BMPs), regulate a dynamic expression pattern of Shh in the ectoderm covering the frontonasal (FNP) and maxillary (MxP) processes. Furthermore, this Shh expression domain contributes to the morphogenetic processes that drive the directional growth of the globular process of the FNP toward the lateral nasal process and MxP, in part by regulating cell proliferation in the facial mesenchyme. The nature of the induction mechanism that we discovered suggests that the process of fusion of the facial primordia is intrinsically buffered against producing maladaptive morphologies, such as clefts of the primary palate, because there appears to be little opportunity for variation to occur during expansion of the Shh expression domain in the ectoderm of the facial primordia. Ultimately, these results might explain why this period of development constitutes a phylotypic stage of facial development among amniotes.

  6. COORDINATED AV.

    ERIC Educational Resources Information Center

    CLEAVES, PAUL C.; AND OTHERS

    THE INSTRUCTIONAL MATERIALS CENTER IS LOCATED IN THE LOCAL HIGH SCHOOL AND SUPPLIES ALL SCHOOLS IN THE AREA. AUDIOVISUAL EQUIPMENT ORDERS, AFTER SELECTIONS ARE MADE BY THE CLASSROOM TEACHER, ARE PROCESSED BY THE CENTER, CONFIRMED AND DELIVERED BY TRUCK THREE TIMES EACH WEEK. EACH SCHOOL HAS A BUILDING COORDINATOR WHO CHECKS THE ORDERS INTO THE…

  7. Dynamic Temperature and Pressure Measurements in the Core of a Propulsion Engine

    NASA Technical Reports Server (NTRS)

    Schuster, Bill; Gordon, Grant; Hultgren, Lennart S.

    2015-01-01

    Dynamic temperature and pressure measurements were made in the core of a TECH977 propulsion engine as part of a NASA funded investigation into indirect combustion noise. Dynamic temperature measurements were made in the combustor, the inter-turbine duct, and the mixer using ten two-wire thermocouple probes. Internal dynamic pressure measurements were made at the same locations using piezoresistive transducers installed in semi-infinite coils. Measurements were acquired at four steady state operating conditions covering the range of aircraft approach power settings. Fluctuating gas temperature spectra were computed from the thermocouple probe voltage measurements using a compensation procedure that was developed under previous NASA test programs. A database of simultaneously acquired dynamic temperature and dynamic pressure measurements was produced. Spectral and cross-spectral analyses were conducted to explore the characteristics of the temperature and pressure fluctuations inside the engine, with a particular focus on attempting to identify the presence of indirect combustion noise.

  8. HIV-1 alters neural and glial progenitor cell dynamics in the central nervous system: coordinated response to opiates during maturation.

    PubMed

    Hahn, Yun Kyung; Podhaizer, Elizabeth M; Hauser, Kurt F; Knapp, Pamela E

    2012-12-01

    HIV-associated neurocognitive disorders (HANDs) are common sequelae of human immunodeficiency virus (HIV) infection, even when viral titers are well controlled by antiretroviral therapy. Evidence in patients and animal models suggests that neurologic deficits are increased during chronic opiate exposure. We have hypothesized that central nervous system (CNS) progenitor cells in both adult and developing CNS are affected by HIV infection and that opiates exacerbate these effects. To examine this question, neural progenitors were exposed to HIV-1 Tat(1-86) in the developing brain of inducible transgenic mice and in vitro. We examined whether Tat affected the proliferation or balance of progenitor populations expressing nestin, Sox2, and Olig2. Disease relevance was further tested by exposing human-derived progenitors to supernatant from HIV-1 infected monocytes. Studies concentrated on striatum, a region preferentially targeted by HIV and opiates. Results were similar among experimental paradigms. Tat or HIV exposure reduced the proliferation of undifferentiated (Sox2(+)) progenitors and oligodendroglial (Olig2(+)) progenitors. Coexposure to morphine exacerbated the effects of Tat or HIV-1(SF162) supernatant, but partially reversed HIV-1(IIIB) supernatant effects. Populations of Sox2(+) and Olig2(+) cells were also reduced by Tat exposure, although progenitor survival was unaffected. In rare instances, p24 immunolabeling was detected in viable human progenitors by confocal imaging. The vulnerability of progenitors is likely to distort the dynamic balance among neuron/glial populations as the brain matures, perhaps contributing to reports that neurologic disease is especially prevalent in pediatric HIV patients. Pediatric disease is atypical in developed regions but remains a serious concern in resource-limited areas where infection occurs commonly at birth and through breast feeding.

  9. Fast ion dynamics measured by collective Thomson scattering

    NASA Astrophysics Data System (ADS)

    Bindslev, Henrik

    2001-10-01

    In magnetically confined fusion plasmas, fast ions, from fusion reactions and auxiliary heating, typically carry a third of the total plasma kinetic energy, and even more of the free energy. This free energy must be channelled into heating the bulk plasma, but is also available for driving waves in the plasma, affecting confinement of bulk and fast ions. We know that fast ions can drive Alfvén waves, affect sawteeth and fishbones. In turn all three can redistribute or ejects the fast ions. Wave particle interaction, also the basis of Ion Cyclotron Resonance Heating (ICRH), depends crucially on the phase space distribution of the fast ions. Conversely the effect waves and instabilities