High Pressure Composite Overwrapped Pressure Vessel (COPV) Development Tests at Cryogenic Temperatures

NASA Technical Reports Server (NTRS)

Ray, David M.; Greene, Nathanael J.; Revilock, Duane; Sneddon, Kirk; Anselmo, Estelle

2008-01-01

Development tests were conducted to evaluate the performance of 2 COPV designs at cryogenic temperatures. This allows for risk reductions for critical components for a Gaseous Helium (GHe) Pressurization Subsystem for an Advanced Propulsion System (APS) which is being proposed for NASA s Constellation project and future exploration missions. It is considered an advanced system since it uses Liquid Methane (LCH4) as the fuel and Liquid Oxygen (LO2) as the oxidizer for the propellant combination mixture. To avoid heating of the propellants to prevent boil-off, the GHe will be stored at subcooled temperatures equivalent to the LO2 temperature. Another advantage of storing GHe at cryogenic temperatures is that more mass of the pressurized GHe can be charged in to a vessel with a smaller volume, hence a smaller COPV, and this creates a significant weight savings versus gases at ambient temperatures. The major challenge of this test plan is to verify that a COPV can safely be used for spacecraft applications to store GHe at a Maximum Operating Pressure (MOP) of 4,500 psig at 140R to 160R (-320 F to -300 F). The COPVs for these tests were provided by ARDE , Inc. who developed a resin system to use at cryogenic conditions and has the capabilities to perform high pressure testing with LN2.

Development of a Numerical Model of Hypervelocity Impact into a Pressurized Composite Overwrapped Pressure Vessel

NASA Technical Reports Server (NTRS)

Garcia, M. A.; Davis, B. A.; Miller, J. E.

2017-01-01

As the outlook for space exploration becomes more ambitious and spacecraft travel deeper into space than ever before, it is increasingly important that propulsion systems perform reliably within the space environment. The increased reliability compels designers to increase design margin at the expense of system mass, which contrasts with the need to limit vehicle mass to maximize payload. Such are the factors that motivate the integration of high specific strength composite materials in the construction of pressure vessels commonly referred to as composite overwrapped pressure vessels (COPV). The COPV consists of a metallic liner for the inner shell of the COPV that is stiff, negates fluid permeation and serves as the anchor for composite laminates or filaments, but the liner itself cannot contain the stresses from the pressurant it contains. The compo-site-fiber reinforced polymer (CFRP) is wound around the liner using a combination of hoop (circumferential) and helical orientations. Careful consideration of wrap orientation allows the composite to evenly bear structural loading and creates the COPV's characteristic high strength to weight ratio. As the CFRP overwrap carries most of the stresses induced by pressurization, damage to the overwrap can affect mission duration, mission success and potentially cause loss-of-vehicle/loss-of-crew. For this reason, it is critical to establish a fundamental understanding of the mechanisms involved in the failure of a stressed composite such as that of the COPV. One of the greatest external threats to the integrity of a spacecraft's COPV is an impact from the meteoroid and orbital debris environments (MMOD). These impacts, even from submillimeter particles, generate extremely high stress states in the CFRP that can damage numerous fibers. As a result of this possibility, initial assumptions in survivability analysis for some human-rated NASA space-craft have assumed that any alteration of the vessel due to impact is considered a catastrophic failure. This assumption is conservative and made due to lack of knowledge on the level of allow-able damage to the composite overwrap that can be sustained and still allow successful completion of the mission. To quantify the allowable damage level to the composite overwrap involves assessing stress redistribution following damage as well as evaluating possible time-dependent mechanisms involved in the COPV response to an impact event. Limited published work in this subject has shown that COPV can withstand at least some level of damage due to high energy impacts. These observations have been confirmed and expanded upon in recent experimental research performed by NASA. This research has demonstrated that there is not only robustness in a COPV to compensate for CFRP damage, but has also identified two significant failure modes for pressurized COPV. The lowest threshold failure mode involves the perforation of the vessel, and the highest threshold failure mode is the catastrophic rupture. While both of these failure modes mean a loss of the COPV, system robustness affords some tolerance to the venting as opposed to the more catastrophic rupture. As a consequence, it is necessary to understand the conditions that result in the transition between these failure modes. The aforementioned experimental research has been performed in both the unpressurized and pressurized condition to identify the damage level that triggered the failure thresh-old. This COPV test program was sponsored by the NASA Engineering and Safety Center (NESC), and tests were performed at NASA White Sands Test Facility (WSTF). Planning and coordination were provided by NASA JSC Hypervelocity Impact Technology (HVIT) group, and the COPVs were provided by the ISS Program. Unpressurized testing has been conducted at the pressure of the vacuum test chamber, while, the pressurized testing has been conducted at 290 +/- 10 bar (4,200 ? 100 psi) using nitrogen as the pressurizing gas, which corresponds to the design pressure for the target COPV. In this research, spherical aluminum projectiles with varying diameter has been chosen as the impactor. For the unpressurized COPV, the dependence of penetration up to the dependence of hole size in the liner has been obtained as a function of impact conditions. For the pressurized research, the dependence of penetration up to rupture has been obtained as a function of im-pact conditions. Two representative post-test photographs of the failed COPV's from a nor-mal impact into the COPV surface are shown in Fig. 1. These images display the dramatic difference between failure modes, venting (Fig. 1a) and rupture (Fig. 1b). For venting, liner perforation, severed composite fibers/tows and ply delamination are commonly observed damage characteristics of this COPV failure mode. In the case of rupture, the COPV typically experienced a separation of its domed regions and severe break-up of the cylindrical region. Fully understanding the transition from venting to rupture experimentally is costly and potentially unachievable for conditions that cannot be generated in the laboratory. These shortcomings have motivated the performance of three-dimensional numerical simulations to expand the existing experimental database. These simulations have been carried out with the nonlinear-structural-dynamics, analysis-tool, CTH. A typical pressure contour plot from an impact simulation of an entire COPV is shown in Fig. 2. To generate the COPV stress state without initiating a shock wave, the pressure in the simulated COPV is ramped up to the final pressure over a millisecond prior to impact of the projectile with nitrogen gas. Figure 2a shows the system in this initial condition. After one millisecond, a projectile is initiated into the simulation and impacts the COPV. Figure 2b shows the system after this impact. In the figure, the onset of venting is represented as the change in pressure (µbar), red to green, at the perforation site. Also seen in the figure is the eroded projectile that had passed into the COPV vessel with the generated shock wave in the pressurant propagating just ahead of the material. In this paper, pertinent experimental details and the development of the material constitutive models necessary for this work along with the efforts to validate their use are dis-cussed. The simulation results are presented and compared with the NASA experimental observations. While work is on-going from this effort, early observations pertinent to the failure threshold are presented.

Elastic Plastic Fracture Analysis of an Aluminum COPV Liner

NASA Technical Reports Server (NTRS)

Forth, Scott; Gregg, Bradley; Bailey, Nathaniel

2012-01-01

Onboard any space-launch vehicle, composite over-wrapped pressure vessels (COPVs) may be utilized by propulsion or environmental control systems. The failure of a COPV has the potential to be catastrophic, resulting in the loss of vehicle, crew or mission. The latest COPV designs have reduced the wall-thickness of the metallic liner to the point where the material strains plastically during operation. At this time, the only method to determine the damage tolerance lifetime (safe-life) of a plastically responding metallic liner is through full-scale COPV testing. Conducting tests costs substantially more and can be far more time consuming than performing an analysis. As a result of this cost, there is a need to establish a qualifying process through the use of a crack growth analysis tool. This paper will discuss fracture analyses of plastically responding metallic liners in COPVs. Uni-axial strain tests have been completed on laboratory specimens to collect elastic-plastic crack growth data. This data has been modeled with the crack growth analysis tool, NASGRO 6.20 to predict the response of laboratory specimens and subsequently the complexity of a COPV.

In-Situ Nondestructive Evaluation of Kevlar(Registered Trademark)and Carbon Fiber Reinforced Composite Micromechanics for Improved Composite Overwrapped Pressure Vessel Health Monitoring

NASA Technical Reports Server (NTRS)

Waller, Jess; Saulsberry, Regor

2012-01-01

NASA has been faced with recertification and life extension issues for epoxy-impregnated Kevlar 49 (K/Ep) and carbon (C/Ep) composite overwrapped pressure vessels (COPVs) used in various systems on the Space Shuttle and International Space Station, respectively. Each COPV has varying criticality, damage and repair histories, time at pressure, and pressure cycles. COPVs are of particular concern due to the insidious and catastrophic burst-before-leak failure mode caused by stress rupture (SR) of the composite overwrap. SR life has been defined [1] as the minimum time during which the composite maintains structural integrity considering the combined effects of stress level(s), time at stress level(s), and associated environment. SR has none of the features of predictability associated with metal pressure vessels, such as crack geometry, growth rate and size, or other features that lend themselves to nondestructive evaluation (NDE). In essence, the variability or surprise factor associated with SR cannot be eliminated. C/Ep COPVs are also susceptible to impact damage that can lead to reduced burst pressure even when the amount of damage to the COPV is below the visual detection threshold [2], thus necessitating implementation of a mechanical damage control plan [1]. Last, COPVs can also fail prematurely due to material or design noncompliance. In each case (SR, impact or noncompliance), out-of-family behavior is expected leading to a higher probability of failure at a given stress, hence, greater uncertainty in performance. For these reasons, NASA has been actively engaged in research to develop NDE methods that can be used during post-manufacture qualification, in-service inspection, and in-situ structural health monitoring. Acoustic emission (AE) is one of the more promising NDE techniques for detecting and monitoring, in real-time, the strain energy release and corresponding stress-wave propagation produced by actively growing flaws and defects in composite materials [3,4,5,6,7,8]. To gain further insight into the mechanisms responsible for composite rupture, broadband modal acoustic emission analysis was used. Also, since AE data reduction proved to be very time consuming, specialized data reduction software was written to automate the process.

Self-Healing Nanocomposites for Reusable Composite Cryotanks

NASA Technical Reports Server (NTRS)

Eberly, Daniel; Ou, Runqing; Karcz, Adam; Skandan, Ganesh

2013-01-01

Composite cryotanks, or composite overwrapped pressure vessels (COPVs), offer advantages over currently used aluminum-lithium cryotanks, particularly with respect to weight savings. Future NASA missions are expected to use COPVs in spaceflight propellant tanks to store fuels, oxidizers, and other liquids for launch and space exploration vehicles. However, reliability, reparability, and reusability of the COPVs are still being addressed, especially in cryogenic temperature applications; this has limited the adoption of COPVs in reusable vehicle designs. The major problem with composites is the inherent brittleness of the epoxy matrix, which is prone to microcrack formation, either from exposure to cryogenic conditions or from impact from different sources. If not prevented, the microcracks increase gas permeation and leakage. Accordingly, materials innovations are needed to mitigate microcrack damage, and prevent damage in the first place, in composite cryotanks. The self-healing technology being developed is capable of healing the microcracks through the use of a novel engineered nanocomposite, where a uniquely designed nanoparticle additive is incorporated into the epoxy matrix. In particular, this results in an enhancement in the burst pressure after cryogenic cycling of the nanocomposite COPVs, relative to the control COPVs. Incorporating a novel, self-healing, epoxy-based resin into the manufacture of COPVs allows repeatable self-healing of microcracks to be performed through the simple application of a low-temperature heat source. This permits COPVs to be reparable and reusable with a high degree of reliability, as microcracks will be remediated. The unique phase-separated morphology that was imparted during COPV manufacture allows for multiple self-healing cycles. Unlike single-target approaches where one material property is often improved at the expense of another, robustness has been introduced to a COPV by a combination of a modified resin and nanoparticle additives. Unique nanoparticles were used that have been surface-functionalized to be compatible with the resin. Both organic and inorganic components toughen the matrix and result in a more impact-resistant COPV. In one resin system containing an inorganic nanomaterial additive, a significant improvement in burst performance was observed after the COPV was cryo-impact-damaged and then self-healed, with a greater than 10% improvement in burst pressure after the self-healing process was performed. Initial cross-sectional analysis via microscopy showed good resin infiltration of the carbon fibers and without voids. To further enhance the capability between the nanomaterial additives and the resin, a surface modification was successfully performed. A second specialty epoxy resin was prepared using a surface modified nanomaterial additive, and COPVs were fabricated. Steps were taken to improve the mechanical properties of the COPVs by using a low-viscosity resin system that contained a different curing agent. This lower viscosity improves the processing of the COPV, and preliminary results show that the burst pressure of these new vessels is 20 to 25% higher than that of the original. The self-healing concept demonstrated in this research and development effort represents a platform technology, and the self-healing property is neither restricted to the particular epoxy system used here, nor to the COPV application. Self-healing is a direct result of a unique phase separated morphology created via the resin and is aided by the nanoparticles. The self-healing function can be introduced to other customer-specific resin systems in coating, bulk, or composite applications provided that the unique phase separated morphology can be enabled in those systems.

Shearography NDE of NASA COPV

NASA Technical Reports Server (NTRS)

Newman, John W.; Santos, Fernando; Saulsbury, Regor; Koshti, Ajay; Russell, Rick; Regez, Brad

2006-01-01

1. 21 Composite Over-wrapped Pressure Vessels (COPV) consisting of Kevlar Space Shuttle Fleet Leaders and Graphite COPV were inspected at NASA WSTF, NM from Sept. 12 through Sept 16. 2. The inspection technique was Pressurization Shearography, tests designed to image composite material damage, degradation or design flaws leading to stress concentrations in the axial or hoop strain load path. 3. The defect types detected consisted of the following: a) Intentional impact damage with known energy. b) Un-intentional impact damage. c) Manufacturing defects. 4. COPV design features leading to strain concentrations detected include: a) Strain concentrations at bosses due to fiber closure pattern. b) Strain concentrations in body of COPV due to fiber wrap pattern. c) Strain concentrations at equator due to liner weld/fiber lay-up.

Composite Overwrapped Pressure Vessels (COPV): Flight Rationale for the Space Shuttle Program

NASA Technical Reports Server (NTRS)

Kezirian, Michael T.; Johnson, Kevin L.; Phoenix, Stuart L.

2011-01-01

Each Orbiter Vehicle (Space Shuttle Program) contains up to 24 Kevlar49/Epoxy Composite Overwrapped Pressure Vessels (COPV) for storage of pressurized gases. In the wake of the Columbia accident and the ensuing Return To Flight (RTF) activities, Orbiter engineers reexamined COPV flight certification. The original COPV design calculations were updated to include recently declassified Kevlar COPV test data from Lawrence Livermore National Laboratory (LLNL) and to incorporate changes in how the Space Shuttle was operated as opposed to orinigially envisioned. 2005 estimates for the probability of a catastrophic failure over the life of the program (from STS-1 through STS-107) were one-in-five. To address this unacceptable risk, the Orbiter Project Office (OPO) initiated a comprehensive investigation to understand and mitigate this risk. First, the team considered and eventually deemed unfeasible procuring and replacing all existing flight COPVs. OPO replaced the two vessels with the highest risk with existing flight spare units. Second, OPO instituted operational improvements in ground procedures to signficiantly reduce risk, without adversely affecting Shuttle capability. Third, OPO developed a comprehensive model to quantify the likelihood of occurrance. A fully-instrumented burst test (recording a lower burst pressure than expected) on a flight-certified vessel provided critical understanding of the behavior of Orbiter COPVs. A more accurate model was based on a newly-compiled comprehensive database of Kevlar data from LLNL and elsewhere. Considering hardware changes, operational improvements and reliability model refinements, the mean reliability was determined to be 0.998 for the remainder of the Shuttle Program (from 2007, for STS- 118 thru STS-135). Since limited hardware resources precluded full model validation through multiple tests, additional model confidence was sought through the first-ever Accelerated Stress Rupture Test (ASRT) of a flown flight article. A Bayesian statistical approach was developed to interpret possible test results. Since the lifetime observed in the ASRT exceeded initial estimates by one to two orders of magnitude, the Space Shuttle Program deemed there was significant conservatism in the model and accepted continued operation with existing flight hardware. Given the variability in tank-to-tank original prooftest response, a non-destructive evaluation (NDE) technique utilizing Raman Spectroscopy was developed to directly measure COPV residual stress state. Preliminary results showed that patterns of low fiber elastic strains over the outside vessel surface, together with measured permanent volume growth during proof, could be directly correlated to increased fiber stress ratios on the inside fibers adjacent to the liner, and thus reduced reliability.

Interrelationship of Nondestructive Evaluation Methodologies Applied to Testing of Composite Overwrapped Pressure Vessels

NASA Technical Reports Server (NTRS)

Leifeste, Mark R.

2007-01-01

Composite Overwrapped Pressure Vessels (COPVs) are commonly used in spacecraft for containment of pressurized gases and fluids, incorporating strength and weight savings. The energy stored is capable of extensive spacecraft damage and personal injury in the event of sudden failure. These apparently simple structures, composed of a metallic media impermeable liner and fiber/resin composite overwrap are really complex structures with numerous material and structural phenomena interacting during pressurized use which requires multiple, interrelated monitoring methodologies to monitor and understand subtle changes critical to safe use. Testing of COPVs at NASA Johnson Space Center White Sands T est Facility (WSTF) has employed multiple in-situ, real-time nondestructive evaluation (NDE) methodologies as well as pre- and post-test comparative techniques to monitor changes in material and structural parameters during advanced pressurized testing. The use of NDE methodologies and their relationship to monitoring changes is discussed based on testing of real-world spacecraft COPVs. Lessons learned are used to present recommendations for use in testing, as well as a discussion of potential applications to vessel health monitoring in future applications.

ANSI/AIAA S-081A, Pressure Vessel Standards Implementation Guidelines

NASA Technical Reports Server (NTRS)

Greene, Nathanael J.

2009-01-01

The stress rupture specification for Composite Overwrapped Pressure Vessels (COPV) is discussed. The composite shell of the COPV shall be designed to meet the design life considering the time it is under sustained load. A Mechcanical Damage Control Plan (MDCP) shall be created and implemented that assures the COPV will not fail due to mechanical damage due to manufacturing, testing, shipping, installation, or flight. Proven processes and procedures for fabrication and repair shall be used to preclude damage or material degradation during material processing, manufacturing operations, and refurbushment.Selected NDI techniques for the liner and/or boss(es) shall be performed before overwrapping with composite. When visual inspection reveals mechanical damage or defects exceeding manufacturing specification levels (and standard repair procedures), the damaged COPV shall be submitted to a material review board (MRB) for disposition. Every COPV shall be subjected to visual and other non-destructive inspection (NDI), per the inspection plan.

Yield Behavior of Solution Treated and Aged Ti-6Al-4V

NASA Technical Reports Server (NTRS)

Ring, Andrew J.; Baker, Eric H.; Salem, Jonathan A.; Thesken, John C.

2014-01-01

Post yield uniaxial tension-compression tests were run on a solution treated and aged (STA), titanium 6-percent aluminum 4-percent vanadium (Ti-6Al-4V) alloy to determine the yield behavior on load reversal. The material exhibits plastic behavior almost immediately on load reversal implying a strong Bauschinger effect. The resultant stress-strain data was compared to a 1D mechanics model and a finite element model used to design a composite overwrapped pressure vessel (COPV). Although the models and experimental data compare well for the initial loading and unloading in the tensile regime, agreement is lost in the compressive regime due to the Bauschinger effect and the assumption of perfect plasticity. The test data presented here are being used to develop more accurate cyclic hardening constitutive models for future finite element design analysis of COPVs.

Composite Overwrapped Pressure Vessels, A Primer

NASA Technical Reports Server (NTRS)

McLaughlan, Pat B.; Forth, Scott C.; Grimes-Ledesma, Lorie R.

2011-01-01

Due to the extensive amount of detailed information that has been published on composite overwrapped pressure vessels (COPVs), this document has been written to serve as a primer for those who desire an elementary knowledge of COPVs and the factors affecting composite safety. In this application, the word "composite" simply refers to a matrix of continuous fibers contained within a resin and wrapped over a pressure barrier to form a vessel for gas or liquid containment. COPVs are currently used at NASA to contain high pressure fluids in propulsion, science experiments, and life support applications. They have a significant weight advantage over all metal vessels but require unique design, manufacturing, and test requirements. COPVs also involve a much more complex mechanical understanding due to the interplay between the composite overwrap and the inner liner. A metallic liner is typically used in a COPV as a fluid permeation barrier. The liner design concepts and requirements have been borrowed from all-metal vessels. However, application of metallic vessel design standards to a very thin liner is not straightforward. Different failure modes exist for COPVs than for all-metal vessels, and understanding of these failure modes is at a much more rudimentary level than for metal vessels.

Material Issues in Space Shuttle Composite Overwrapped Pressure Vessels

NASA Technical Reports Server (NTRS)

Sutter, James K.; Jensen, Brian J.; Gates, Thomas S.; Morgan, Roger J.; Thesken, John C.; Phoenix, S. Leigh

2006-01-01

Composite Overwrapped Pressure Vessels (COPV) store gases used in four subsystems for NASA's Space Shuttle Fleet. While there are 24 COPV on each Orbiter ranging in size from 19-40", stress rupture failure of a pressurized Orbiter COPV on the ground or in flight is a catastrophic hazard and would likely lead to significant damage/loss of vehicle and/or life and is categorized as a Crit 1 failure. These vessels were manufactured during the late 1970's and into the early 1980's using Titanium liners, Kevlar 49 fiber, epoxy matrix resin, and polyurethane coating. The COPVs are pressurized periodically to 3-5ksi and therefore experience significant strain in the composite overwrap. Similar composite vessels were developed in a variety of DOE Programs (primarily at Lawrence Livermore National Laboratories or LLNL), as well as for NASA Space Shuttle Fleet Leader COPV program. The NASA Engineering Safety Center (NESC) formed an Independent Technical Assessment (ITA) team whose primary focus was to investigate whether or not enough composite life remained in the Shuttle COPV in order to provide a strategic rationale for continued COPV use aboard the Space Shuttle Fleet with the existing 25-year-old vessels. Several material science issues were examined and will be discussed in this presentation including morphological changes to Kevlar 49 fiber under stress, manufacturing changes in Kevlar 49 and their effect on morphology and tensile strength, epoxy resin strain, composite creep, degradation of polyurethane coatings, and Titanium yield characteristics.

Bayes Analysis and Reliability Implications of Stress-Rupture Testing a Kevlar/Epoxy COPV using Temperature and Pressure Acceleration

NASA Technical Reports Server (NTRS)

Phoenix, S. Leigh; Kezirian, Michael T.; Murthy, Pappu L. N.

2009-01-01

Composite Overwrapped Pressure Vessel (COPVs) that have survived a long service time under pressure generally must be recertified before service is extended. Sometimes lifetime testing is performed on an actual COPV in service in an effort to validate the reliability model that is the basis for certifying the continued flight worthiness of its sisters. Currently, testing of such a Kevlar49(registered TradeMark)/epoxy COPV is nearing completion. The present paper focuses on a Bayesian statistical approach to analyze the possible failure time results of this test and to assess the implications in choosing between possible model parameter values that in the past have had significant uncertainty. The key uncertain parameters in this case are the actual fiber stress ratio at operating pressure, and the Weibull shape parameter for lifetime; the former has been uncertain due to ambiguities in interpreting the original and a duplicate burst test. The latter has been uncertain due to major differences between COPVs in the data base and the actual COPVs in service. Any information obtained that clarifies and eliminates uncertainty in these parameters will have a major effect on the predicted reliability of the service COPVs going forward. The key result is that the longer the vessel survives, the more likely the more optimistic stress ratio is correct. At the time of writing, the resulting effect on predicted future reliability is dramatic, increasing it by about one nine , that is, reducing the probability of failure by an order of magnitude. However, testing one vessel does not change the uncertainty on the Weibull shape parameter for lifetime since testing several would be necessary.

Systemic Immunization with Papillomavirus L1 Protein Completely Prevents the Development of Viral Mucosal Papillomas

NASA Astrophysics Data System (ADS)

Suzich, Joann A.; Ghim, Shin-Je; Palmer-Hill, Frances J.; White, Wendy I.; Tamura, James K.; Bell, Judith A.; Newsome, Joseph A.; Bennett Jenson, A.; Schlegel, Richard

1995-12-01

Infection of mucosal epithelium by papillomaviruses is responsible for the induction of genital and oral warts and plays a critical role in the development of human cervical and oropharyngeal cancer. We have employed a canine model to develop a systemic vaccine that completely protects against experimentally induced oral mucosal papillomas. The major capsid protein, L1, of canine oral papillomavirus (COPV) was expressed in Sf9 insect cells in native conformation. L1 protein, which self-assembled into virus-like particles, was purified on CsCl gradients and injected intradermally into the foot pad of beagles. Vaccinated animals developed circulating antibodies against COPV and became completely resistant to experimental challenge with COPV. Successful immunization was strictly dependent upon native L1 protein conformation and L1 type. Partial protection was achieved with as little as 0.125 ng of L1 protein, and adjuvants appeared useful for prolonging the host immune response. Serum immunoglobulins passively transferred from COPV L1-immunized beagles to naive beagles conferred protection from experimental infection with COPV. Our results indicate the feasibility of developing a human vaccine to prevent mucosal papillomas, which can progress to malignancy.

Three-Dimensional Digital Image Correlation of a Composite Overwrapped Pressure Vessel During Hydrostatic Pressure Tests

NASA Technical Reports Server (NTRS)

Revilock, Duane M., Jr.; Thesken, John C.; Schmidt, Timothy E.

2007-01-01

Ambient temperature hydrostatic pressurization tests were conducted on a composite overwrapped pressure vessel (COPV) to understand the fiber stresses in COPV components. Two three-dimensional digital image correlation systems with high speed cameras were used in the evaluation to provide full field displacement and strain data for each pressurization test. A few of the key findings will be discussed including how the principal strains provided better insight into system behavior than traditional gauges, a high localized strain that was measured where gages were not present and the challenges of measuring curved surfaces with the use of a 1.25 in. thick layered polycarbonate panel that protected the cameras.

The Safety Course Design and Operations of Composite Overwrapped Pressure Vessels (COPV)

NASA Technical Reports Server (NTRS)

Saulsberry, Regor; Prosser, William

2015-01-01

Following a Commercial Launch Vehicle On-Pad COPV (Composite Overwrapped Pressure Vessels) failure, a request was received by the NESC (NASA Engineering and Safety Center) June 14, 2014. An assessment was approved July 10, 2014, to develop and assess the capability of scanning eddy current (EC) nondestructive evaluation (NDE) methods for mapping thickness and inspection for flaws. Current methods could not identify thickness reduction from necking and critical flaw detection was not possible with conventional dye penetrant (PT) methods, so sensitive EC scanning techniques were needed. Developmental methods existed, but had not been fully developed, nor had the requisite capability assessment (i.e., a POD (Probability of Detection) study) been performed.

Continued Development of Meandering Winding Magnetometer (MWM (Register Trademark)) Eddy Current Sensors for the Health Monitoring, Modeling and Damage Detection of Composite Overwrapped Pressure Vessels

NASA Technical Reports Server (NTRS)

Russell, Richard; Wincheski, Russell; Jablonski, David; Washabaugh, Andy; Sheiretov, Yanko; Martin, Christopher; Goldfine, Neil

2011-01-01

Composite Overwrapped Pressure Vessels (COPVs) are used in essentially all NASA spacecraft, launch. vehicles and payloads to contain high-pressure fluids for propulsion, life support systems and science experiments. Failure of any COPV either in flight or during ground processing would result in catastrophic damage to the spacecraft or payload, and could lead to loss of life. Therefore, NASA continues to investigate new methods to non-destructively inspect (NDE) COPVs for structural anomalies and to provide a means for in-situ structural health monitoring (SHM) during operational service. Partnering with JENTEK Sensors, engineers at NASA, Kennedy Space Center have successfully conducted a proof-of-concept study to develop Meandering Winding Magnetometer (MWM) eddy current sensors designed to make direct measurements of the stresses of the internal layers of a carbon fiber composite wrapped COPV. During this study three different MWM sensors were tested at three orientations to demonstrate the ability of the technology to measure stresses at various fiber orientations and depths. These results showed good correlation with actual surface strain gage measurements. MWM-Array technology for scanning COPVs can reliably be used to image and detect mechanical damage. To validate this conclusion, several COPVs were scanned to obtain a baseline, and then each COPV was impacted at varying energy levels and then rescanned. The baseline subtracted images were used to demonstrate damage detection. These scans were performed with two different MWM-Arrays. with different geometries for near-surface and deeper penetration imaging at multiple frequencies and in multiple orientations of the linear MWM drive. This presentation will include a review of micromechanical models that relate measured sensor responses to composite material constituent properties, validated by the proof of concept study, as the basis for SHM and NDE data analysis as well as potential improvements including design changes to miniaturize and make the sensors durable in the vacuum of space

Bayes Analysis and Reliability Implications of Stress-Rupture Testing a Kevlar/Epoxy COPV Using Temperature and Pressure Acceleration

NASA Technical Reports Server (NTRS)

Phoenix, S. Leigh; Kezirian, Michael T.; Murthy, Pappu L. N.

2009-01-01

Composite Overwrapped Pressure Vessels (COPVs) that have survived a long service time under pressure generally must be recertified before service is extended. Flight certification is dependent on the reliability analysis to quantify the risk of stress rupture failure in existing flight vessels. Full certification of this reliability model would require a statistically significant number of lifetime tests to be performed and is impractical given the cost and limited flight hardware for certification testing purposes. One approach to confirm the reliability model is to perform a stress rupture test on a flight COPV. Currently, testing of such a Kevlar49 (Dupont)/epoxy COPV is nearing completion. The present paper focuses on a Bayesian statistical approach to analyze the possible failure time results of this test and to assess the implications in choosing between possible model parameter values that in the past have had significant uncertainty. The key uncertain parameters in this case are the actual fiber stress ratio at operating pressure, and the Weibull shape parameter for lifetime; the former has been uncertain due to ambiguities in interpreting the original and a duplicate burst test. The latter has been uncertain due to major differences between COPVs in the database and the actual COPVs in service. Any information obtained that clarifies and eliminates uncertainty in these parameters will have a major effect on the predicted reliability of the service COPVs going forward. The key result is that the longer the vessel survives, the more likely the more optimistic stress ratio model is correct. At the time of writing, the resulting effect on predicted future reliability is dramatic, increasing it by about one "nine," that is, reducing the predicted probability of failure by an order of magnitude. However, testing one vessel does not change the uncertainty on the Weibull shape parameter for lifetime since testing several vessels would be necessary.

Application of Raman Spectroscopy for Nondestructive Evaluation of Composite Materials

NASA Technical Reports Server (NTRS)

Washer, Glenn A.; Brooks, Thomas M. B.; Saulsberry, Regor

2007-01-01

This paper will present an overview of efforts to investigate the application of Raman spectroscopy for the characterization of Kevlar materials. Raman spectroscopy is a laser technique that is sensitive to molecular interactions in materials such as Kevlar, graphite and carbon used in composite materials. The overall goal of this research reported here is to evaluate Raman spectroscopy as a potential nondestructive evaluation (NDE) tool for the detection of stress rupture in Kevlar composite over-wrapped pressure vessels (COPVs). Characterization of the Raman spectra of Kevlar yarn and strands will be presented and compared with analytical models provided in the literature. Results of testing to investigate the effects of creep and high-temperature aging on the Raman spectra will be presented.

Detection of Antibodies against Epidermodysplasia Verruciformis-Associated Canine Papillomavirus 3 in Sera of Dogs from Europe and Africa by Enzyme-Linked Immunosorbent Assay▿ †

PubMed Central

Lange, C. E.; Tobler, K.; Favrot, C.; Müller, M.; Nöthling, J. O.; Ackermann, M.

2009-01-01

The role of papillomaviruses (PVs) in the development of canine cancers is controversial. However, recently a novel canine PV (CPV3) was detected in a dog affected with a condition reminiscent of epidermodysplasia verruciformis (EV). The aim of the present study was to investigate the seroprevalence of CPV3 by using generic enzyme-linked immunosorbent assays (ELISAs) for the detection of antibodies against either canine oral PV (COPV) or CPV3. Therefore, the capsid proteins of both PV types were expressed as glutathione S-transferase fusion protein antigens and adsorbed to glutathione-casein-coated ELISA plates. After showing that PV type-specific antibodies could be detected in the sera from dogs with confirmed COPV or CPV3 infection, CPV3- and COPV-seropositive samples were detected in two sets of canine sera collected in Switzerland and South Africa, respectively. We found specific antibodies against COPV and CPV3 among the tested sera and also a large number that were positive for both antigens. The seroprevalences of PV antibodies of 21.9% (COPV) and 26.9% (CPV3) among the tested dogs from South Africa were higher than those among the dogs from Switzerland at 10.5% (COPV) and 1.3% (CPV3). Our data suggest a need for further CPV-related seroepidemiological surveys in different countries, especially in the context of clinical manifestations and possible breed predispositions. For this purpose, the newly developed ELISAs can be a useful tool. PMID:19038784

Use of Modal Acoustic Emission to Monitor Damage Progression in Carbon Fiber/Epoxy Tows and Implications for Composite Structures

NASA Technical Reports Server (NTRS)

Waller, Jess M.; Saulsberry, Regor L.; Nichols, Charles T.; Wentzel, Daniel J.

2010-01-01

This slide presentation reviews the use of Modal Acoustic Emission to monitor damage progression to carbon fiber/epoxy tows. There is a risk for catastrophic failure of composite overwrapped pressure vessels (COPVs) due to burst-before-leak (BBL) stress rupture (SR) failure of carbon-epoxy (C/Ep) COPVs. A lack of quantitative nondestructive evaluation (NDE) is causing problems in current and future spacecraft designs. It is therefore important to develop and demonstrate critical NDE that can be implemented during stages of the design process since the observed rupture can occur with little of no advanced warning. Therefore a program was required to develop quantitative acoustic emission (AE) procedures specific to C/Ep overwraps, but which also have utility for monitoring damage accumulation in composite structure in general, and to lay the groundwork for establishing critical thresholds for accumulated damage in composite structures, such as COPVs, so that precautionary or preemptive engineering steps can be implemented to minimize of obviate the risk of catastrophic failure. A computed Felicity Ratio (FR) coupled with fast Fourier Transform (FFT) frequency analysis shows promise as an analytical pass/fail criterion. The FR analysis and waveform and FFT analysis are reviewed

Customized Noise-Stimulation Intensity for Bipedal Stability and Unipedal Balance Deficits Associated With Functional Ankle Instability

PubMed Central

Ross, Scott E.; Linens, Shelley W.; Wright, Cynthia J.; Arnold, Brent L.

2013-01-01

Context: Stochastic resonance stimulation (SRS) administered at an optimal intensity could maximize the effects of treatment on balance. Objective: To determine if a customized optimal SRS intensity is better than a traditional SRS protocol (applying the same percentage sensory threshold intensity for all participants) for improving double- and single-legged balance in participants with or without functional ankle instability (FAI). Design: Case-control study with an embedded crossover design. Setting: Laboratory. Patients or Other Participants: Twelve healthy participants (6 men, 6 women; age = 22 ± 2 years, height = 170 ± 7 cm, mass = 64 ± 10 kg) and 12 participants (6 men, 6 women; age = 23 ± 3 years, height = 174 ± 8 cm, mass = 69 ± 10 kg) with FAI. Intervention(s): The SRS optimal intensity level was determined by finding the intensity from 4 experimental intensities at the percentage sensory threshold (25% [SRS25], 50% [SRS50], 75% [SRS75], 90% [SRS90]) that produced the greatest improvement in resultant center-of-pressure velocity (R-COPV) over a control condition (SRS0) during double-legged balance. We examined double- and single-legged balance tests, comparing optimal SRS (SRSopt1) and SRS0 using a battery of center-of-pressure measures in the frontal and sagittal planes. Main Outcome Measure(s): Anterior-posterior (A-P) and medial-lateral (M-L) center-of-pressure velocity (COPV) and center-of-pressure excursion (COPE), R-COPV, and 95th percentile center-of-pressure area ellipse (COPA-95). Results: Data were organized into bins that represented optimal (SRSopt1), second (SRSopt2), third (SRSopt3), and fourth (SRSopt4) improvement over SRS0. The SRSopt1 enhanced R-COPV (P ≤ .05) over SRS0 and other SRS conditions (SRS0 = 0.94 ± 0.32 cm/s, SRSopt1 = 0.80 ± 0.19 cm/s, SRSopt2 = 0.88 ± 0.24 cm/s, SRSopt3 = 0.94 ± 0.25 cm/s, SRSopt4 = 1.00 ± 0.28 cm/s). However, SRS did not improve R-COPV over SRS0 when data were categorized by sensory threshold. Furthermore, SRSopt1 improved double-legged balance over SRS0 from 11% to 25% in all participants for the center-of-pressure frontal- and sagittal-plane assessments (P ≤ .05). The SRSopt1 also improved single-legged balance over SRS0 from 10% to 17% in participants with FAI for the center-of-pressure frontal- and sagittal-plane assessments (P ≤ .05). The SRSopt1 did not improve single-legged balance in participants with stable ankles. Conclusions: The SRSopt1 improved double-legged balance and transfers to enhancing single-legged balance deficits associated with FAI. PMID:23724774

Composite Overwrapped Pressure Vessel (COPV) Stress Rupture Testing

NASA Technical Reports Server (NTRS)

Greene, Nathanael J.; Saulsberry, Regor L.; Leifeste, Mark R.; Yoder, Tommy B.; Keddy, Chris P.; Forth, Scott C.; Russell, Rick W.

2010-01-01

This paper reports stress rupture testing of Kevlar(TradeMark) composite overwrapped pressure vessels (COPVs) at NASA White Sands Test Facility. This 6-year test program was part of the larger effort to predict and extend the lifetime of flight vessels. Tests were performed to characterize control parameters for stress rupture testing, and vessel life was predicted by statistical modeling. One highly instrumented 102-cm (40-in.) diameter Kevlar(TradeMark) COPV was tested to failure (burst) as a single-point model verification. Significant data were generated that will enhance development of improved NDE methods and predictive modeling techniques, and thus better address stress rupture and other composite durability concerns that affect pressure vessel safety, reliability and mission assurance.

Eddy Current COPV Overwrap and Liner Thickness Measurement System and Data Analysis for 40-Inch Kevlar COPVs SN002 and SN027

NASA Technical Reports Server (NTRS)

Wincheski, Russell A.

2008-01-01

As part of the health assessment of flight spare 40in diameter Kevlar composite overwrapped pressure vessels (COPVs) SN002 and SN027 an eddy current characterization of the composite and liner thickness change during pressurization was requested under WSTF-TP-1085-07.A, "Space Shuttle Orbiter Main Propulsion System P/N MC282-0082-0101 S/N 002 and Orbital Maneuvering System P/N MC282-0082-001 S/N 027 COPV Health Assessment." The through the thickness strains have been determined to be an important parameter in the analysis of the reliability and likelihood of stress rupture failure. Eddy current techniques provide a means to measure these thicknesses changes based upon the change in impedance of an eddy current sensor mounted on the exterior of the vessel. Careful probe and technique design have resulted in the capability to independently measure the liner and overwrap thickness changes to better than +/- 0.0005 in. at each sensor location. Descriptions of the inspection system and test results are discussed.

Composite Overwrapped Pressure Vessels (COPV): Developing Flight Rationale for the Space Shuttle Program

NASA Technical Reports Server (NTRS)

Kezirian, Michael T.

2010-01-01

Introducing composite vessels into the Space Shuttle Program represented a significant technical achievement. Each Orbiter vehicle contains 24 (nominally) Kevlar tanks for storage of pressurized helium (for propulsion) and nitrogen (for life support). The use of composite cylinders saved 752 pounds per Orbiter vehicle compared with all-metal tanks. The weight savings is significant considering each Shuttle flight can deliver 54,000 pounds of payload to the International Space Station. In the wake of the Columbia accident and the ensuing Return to Flight activities, the Space Shuttle Program, in 2005, re-examined COPV hardware certification. Incorporating COPV data that had been generated over the last 30 years and recognizing differences between initial Shuttle Program requirements and current operation, a new failure mode was identified, as composite stress rupture was deemed credible. The Orbiter Project undertook a comprehensive investigation to quantify and mitigate this risk. First, the engineering team considered and later deemed as unfeasible the option to replace existing all flight tanks. Second, operational improvements to flight procedures were instituted to reduce the flight risk and the danger to personnel. Third, an Orbiter reliability model was developed to quantify flight risk. Laser profilometry inspection of several flight COPVs identified deep (up to 20 mil) depressions on the tank interior. A comprehensive analysis was performed and it confirmed that these observed depressions were far less than the criterion which was established as necessary to lead to liner buckling. Existing fleet vessels were exonerated from this failure mechanism. Because full validation of the Orbiter Reliability Model was not possible given limited hardware resources, an Accelerated Stress Rupture Test of a flown flight vessel was performed to provide increased confidence. A Bayesian statistical approach was developed to evaluate possible test results with respect to the model credibility and thus flight rationale for continued operation of the Space Shuttle with existing flight hardware. A non-destructive evaluation (NDE) technique utilizing Raman Spectroscopy was developed to directly measure the overwrap residual stress state. Preliminary results provide optimistic results that patterns of fluctuation in fiber elastic strains over the outside vessel surface could be directly correlated with increased fiber stress ratios and thus reduced reliability.

40-in. OMS Kevlar(Registered Trademark) COPV S/N 007 Stress Rupture Test NDE

NASA Technical Reports Server (NTRS)

Saulsberry, Regor; Greene, Nate; Forth, Scott; Leifeste, Mark; Gallus, Tim; Yoder, Tommy; Keddy, Chris; Mandaras, Eric; Wincheski, Buzz; Williams, Philip;

A Theoretical Investigation of Composite Overwrapped Pressure Vessel (COPV) Mechanics Applied to NASA Full Scale Tests

NASA Technical Reports Server (NTRS)

Thesken, John C.; Murthy, Pappu L. N.; Phoenix, S. L.; Greene, N.; Palko, Joseph L.; Eldridge, Jeffrey; Sutter, James; Saulsberry, R.; Beeson, H.

2009-01-01

A theoretical investigation of the factors controlling the stress rupture life of the National Aeronautics and Space Administration's (NASA) composite overwrapped pressure vessels (COPVs) continues. Kevlar (DuPont) fiber overwrapped tanks are of particular concern due to their long usage and the poorly understood stress rupture process in Kevlar filaments. Existing long term data show that the rupture process is a function of stress, temperature and time. However due to the presence of a load sharing liner, the manufacturing induced residual stresses and the complex mechanical response, the state of actual fiber stress in flight hardware and test articles is not clearly known. This paper is a companion to a previously reported experimental investigation and develops a theoretical framework necessary to design full-scale pathfinder experiments and accurately interpret the experimentally observed deformation and failure mechanisms leading up to static burst in COPVs. The fundamental mechanical response of COPVs is described using linear elasticity and thin shell theory and discussed in comparison to existing experimental observations. These comparisons reveal discrepancies between physical data and the current analytical results and suggest that the vessel s residual stress state and the spatial stress distribution as a function of pressure may be completely different from predictions based upon existing linear elastic analyses. The 3D elasticity of transversely isotropic spherical shells demonstrates that an overly compliant transverse stiffness relative to membrane stiffness can account for some of this by shifting a thin shell problem well into the realm of thick shell response. The use of calibration procedures are demonstrated as calibrated thin shell model results and finite element results are shown to be in good agreement with the experimental results. The successes reported here have lead to continuing work with full scale testing of larger NASA COPV hardware.

Fiber Breakage Model for Carbon Composite Stress Rupture Phenomenon: Theoretical Development and Applications

NASA Technical Reports Server (NTRS)

Murthy, Pappu L. N.; Phoenix, S. Leigh; Grimes-Ledesma, Lorie

2010-01-01

Stress rupture failure of Carbon Composite Overwrapped Pressure Vessels (COPVs) is of serious concern to Science Mission and Constellation programs since there are a number of COPVs on board space vehicles with stored gases under high pressure for long durations of time. It has become customary to establish the reliability of these vessels using the so called classic models. The classical models are based on Weibull statistics fitted to observed stress rupture data. These stochastic models cannot account for any additional damage due to the complex pressure-time histories characteristic of COPVs being supplied for NASA missions. In particular, it is suspected that the effects of proof test could significantly reduce the stress rupture lifetime of COPVs. The focus of this paper is to present an analytical appraisal of a model that incorporates damage due to proof test. The model examined in the current paper is based on physical mechanisms such as micromechanics based load sharing concepts coupled with creep rupture and Weibull statistics. For example, the classic model cannot accommodate for damage due to proof testing which every flight vessel undergoes. The paper compares current model to the classic model with a number of examples. In addition, several applications of the model to current ISS and Constellation program issues are also examined.

Composite Overwrapped Pressure Vessels: Database Extension Task 3.0 and Impact Damage Effects Control Task 8.0

NASA Technical Reports Server (NTRS)

Beeson, Harold D.; Davis, Dennis D.; Ross, William L., Sr.; Tapphorn, Ralph M.

2002-01-01

This document represents efforts accomplished at the NASA Johnson Space Center White Sands Test Facility (WSTF) in support of the Enhanced Technology for Composite Overwrapped Pressure Vessels (COPV) Program, a joint research and technology effort among the U.S. Air Force, NASA, and the Aerospace Corporation. WSTF performed testing for several facets of the program. Testing that contributed to the Task 3.0 COPV database extension objective included baseline structural strength, failure mode and safe-life, impact damage tolerance, sustained load/impact effect, and materials compatibility. WSTF was also responsible for establishing impact protection and control requirements under Task 8.0 of the program. This included developing a methodology for establishing an impact control plan. Seven test reports detail the work done at WSTF. As such, this document contributes to the database of information regarding COPV behavior that will ensure performance benefits and safety are maintained throughout vessel service life.

Evaluation of Carbon Composite Overwrap Pressure Vessels Fabricated Using Ionic Liquid Epoxies Project

NASA Technical Reports Server (NTRS)

Grugel, Richard

2015-01-01

The intent of the work proposed here is to ascertain the viability of ionic liquid (IL) epoxy based carbon fiber composites for use as storage tanks at cryogenic temperatures. This IL epoxy has been specifically developed to address composite cryogenic tank challenges associated with achieving NASA's in-space propulsion and exploration goals. Our initial work showed that an unadulterated ionic liquid (IL) carbon-fiber composite exhibited improved properties over an optimized commercial product at cryogenic temperatures. Subsequent investigative work has significantly improved the IL epoxy and our first carbon-fiber Composite Overwrap Pressure Vessel (COPV) was successfully fabricated. Here additional COPVs, using a further improved IL epoxy, will be fabricated and pressure tested at cryogenic temperatures with the results rigorously analyzed. Investigation of the IL composite for lower pressure liner-less cryogenic tank applications will also be initiated. It is expected that the current Technology Readiness Level (TRL) will be raised from about TRL 3 to TRL 5 where unambiguous predictions for subsequent development/testing can be made.

A Theoretical Investigation of Composite Overwrapped Pressure Vessel (COPV) Mechanics Applied to NASA Full Scale Tests

NASA Technical Reports Server (NTRS)

Greene, N.; Thesken, J. C.; Murthy, P. L. N.; Phoenix, S. L.; Palko, J.; Eldridge, J.; Sutter, J.; Saulsberry, R.; Beeson, H.

2006-01-01

A theoretical investigation of the factors controlling the stress rupture life of the National Aeronautics and Space Agency's (NASA) composite overwrapped pressure vessels (COPVs) continues. Kevlar(TradeMark) fiber overwrapped tanks are of particular concern due to their long usage and the poorly understood stress rupture process in Kevlar(TradeMark) filaments. Existing long term data show that the rupture process is a function of stress, temperature and time. However, due to the presence of a load sharing liner, the manufacturing induced residual stresses and the complex mechanical response, the state of actual fiber stress in flight hardware and test articles is not clearly known. This paper is a companion to the experimental investigation reported in [1] and develops a theoretical framework necessary to design full-scale pathfinder experiments and accurately interpret the experimentally observed deformation and failure mechanisms leading up to static burst in COPVs. The fundamental mechanical response of COPVs is described using linear elasticity and thin shell theory and discussed in comparison to existing experimental observations. These comparisons reveal discrepancies between physical data and the current analytical results and suggest that the vessel's residual stress state and the spatial stress distribution as a function of pressure may be completely different from predictions based upon existing linear elastic analyses. The 3D elasticity of transversely isotropic spherical shells demonstrates that an overly compliant transverse stiffness relative to membrane stiffness can account for some of this by shifting a thin shell problem well into the realm of thick shell response. The use of calibration procedures are demonstrated as calibrated thin shell model results and finite element results are shown to be in good agreement with the experimental results. The successes reported here have lead to continuing work with full scale testing of larger NASA COPV hardware.

Use of Raman Spectroscopy and Delta Volume Growth from Void Collapse to Assess Overwrap Stress Gradients Compromising the Reliability of Large Kevlar/Epoxy COPVs

NASA Technical Reports Server (NTRS)

Kezirian, Michael T.; Phoenix, S. Leigh; Eldridge, Jeffrey I.

2009-01-01

Composite Overwrapped Pressure Vessels (COPVs) are frequently used for storing pressurized gases aboard spacecraft and aircraft when weight saving is desirable compared to all-metal versions. Failure mechanisms in fibrous COPVs and variability in lifetime can be very different from their metallic counterparts; in the former, catastrophic stress-rupture can occur with virtually no warning, whereas in latter, a leak before burst design philosophy can be implemented. Qualification and certification typically requires only one burst test on a production sample (possibly after several pressure cycles) and the vessel need only meet a design burst strength (the maximum operating pressure divided by a knockdown factor). Typically there is no requirement to assess variability in burst strength or lifetime, much less determine production and materials processing parameters important to control of such variability. Characterizing such variability and its source is crucial to models for calculating required reliability over a given lifetime (e.g. R = 0.9999 for 15 years). In this paper we present a case study of how lack of control of certain process parameters in COPV manufacturing can result in variations among vessels and between production runs that can greatly increase uncertainty and reduce reliability. The vessels considered are 40-inch ( NASA Glenn Research center, Cleveland, OH, 44135 29,500 in3 ) spherical COPVs with a 0.74 in. thick Kevlar49/epoxy overwrap and with a titanium liner of which 34 were originally produced. Two burst tests were eventually performed that unexpectedly differed by almost 5%, and were 10% lower than anticipated from burst tests on 26-inch sister vessels similar in every detail. A major observation from measurements made during proof testing (autofrettage) of the 40-inch vessels was that permanent volume growth from liner yielding varied by a factor of more than two (150 in3 to 360 in3 ), which suggests large differences in the residual stress gradient through their overwraps. This resulted in large uncertainty in true fiber stress ratio (fiber stress at operating pressure divided by fiber stress at burst) which governs lifetime. The vessels were originally designed with tight safety margins, so it became crucial to develop a non-destructive evaluation (NDE) technique to directly measure the overwrap residual stress state of each vessel, and to identify those vessels at highest risk of having poor reliability. This paper describes a Raman Spectroscopy technique for measuring certain patterns of fluctuation in fiber elastic strains over the outside vessel surface (where all but one wrap is exposed at certain locations) that are shown to directly correlate to increased fiber stress ratios and reduced reliability.

Hybrid Tank Technology

NASA Technical Reports Server (NTRS)

2004-01-01

Researchers have accomplished great advances in pressure vessel technology by applying high-performance composite materials as an over-wrap to metal-lined pressure vessels. These composite over-wrapped pressure vessels (COPVs) are used in many areas, from air tanks for firefighters and compressed natural gas tanks for automobiles, to pressurant tanks for aerospace launch vehicles and propellant tanks for satellites and deep-space exploration vehicles. NASA and commercial industry are continually striving to find new ways to make high-performance pressure vessels safer and more reliable. While COPVs are much lighter than all-metal pressure vessels, the composite material, typically graphite fibers with an epoxy matrix resin, is vulnerable to impact damage. Carbon fiber is most frequently used for the high-performance COPV applications because of its high strength-to-weight characteristics. Other fibers have been used, but with limitations. For example, fiberglass is inexpensive but much heavier than carbon. Aramid fibers are impact resistant but have less strength than carbon and their performance tends to deteriorate.

Development of Meandering Winding Magnetometer (MWM (Register Trademark)) Eddy Current Sensors for the Health Monitoring, Modeling and Damage Detection of High Temperature Composite Materials

NASA Technical Reports Server (NTRS)

Russell, Richard; Washabaugh, Andy; Sheiretov, Yanko; Martin, Christopher; Goldfine, Neil

2011-01-01

The increased use of high-temperature composite materials in modern and next generation aircraft and spacecraft have led to the need for improved nondestructive evaluation and health monitoring techniques. Such technologies are desirable to improve quality control, damage detection, stress evaluation and temperature measurement capabilities. Novel eddy current sensors and sensor arrays, such as Meandering Winding Magnetometers (MWMs) have provided alternate or complimentary techniques to ultrasound and thermography for both nondestructive evaluation (NDE) and structural health monitoring (SHM). This includes imaging of composite material quality, damage detection and .the monitoring of fiber temperatures and multidirectional stresses. Historically, implementation of MWM technology for the inspection of the Space Shuttle Orbiter Reinforced Carbon-Carbon Composite (RCC) leading edge panels was developed by JENTEK Sensors and was subsequently transitioned by NASA as an operational pre and post flight in-situ inspection at the Kennedy Space Center. A manual scanner, which conformed'automatically to the curvature of the RCC panels was developed and used as a secondary technique if a defect was found during an infrared thermography screening, During a recent proof of concept study on composite overwrapped pressure vessels (COPV's), three different MWM sensors were tested at three orientations to demonstrate the ability of the technology to measure stresses at various fiber orientations and depths. These results showed excellent correlation with actual surface strain gage measurements. Recent advancements of this technology have been made applying MWM sensor technology for scanning COPVs for mechanical damage. This presentation will outline the recent advance in the MWM.technology and the development of MWM techniques for NDE and SHM of carbon wraped composite overwrapped pressure vessels (COPVs) including the measurement of internal stresses via a surface mounted sensor array. In addition, this paper will outline recent efforts to produce sensors capable of making real-time measurements at temperatures up to 850 C, and discuss previous results demonstrating capability to monitor carbon fiber temperature changes within a composite material.

Composite Overwrap Fragmentation Observations, Concerns, and Recommendations

NASA Technical Reports Server (NTRS)

Bangham, Mike; Hovater, Mary

2017-01-01

A series of test activities has raised some concerns about the generation of orbital debris caused by failures of composite overwrapped pressure vessels (COPVs). These tests have indicated that a large number of composite fragments can be produced by either pressure burst failures or by high-speed impacts. A review of prior high-speed tests with COPV indicates that other tests have produced large numbers of composite fragments. As was the case with the test referenced here, the tests tended to produce a large number of small composite fragments with relatively low velocities induced by the impact and or gas expansion.

Providing Pressurized Gasses to the International Space Station (ISS): Developing a Composite Overwrapped Pressure Vessel (COPV) for the Safe Transport of Oxygen and Nitrogen

NASA Technical Reports Server (NTRS)

Kezirian, Michael; Cook, Anthony; Dick, Brandon; Phoenix, S. Leigh

2012-01-01

To supply oxygen and nitrogen to the International Space Station, a COPV tank is being developed to meet requirements beyond that which have been flown. In order to "Ship Full' and support compatibility with a range of launch site operations, the vessel was designed for certification to International Standards (ISO) that have a different approach than current NASA certification approaches. These requirements were in addition to existing NASA certification standards had to be met. Initial risk-reduction development tests have been successful. Qualification is in progress.

NASA/University JOint VEnture (JOVE) Program: Transverse Shear Moduli Using the Torsional Responses of Rectangular Laminates

NASA Technical Reports Server (NTRS)

Bogan, Sam

2001-01-01

The first year included a study of the non-visible damage of composite overwrapped pressure vessels with B. Poe of the Materials Branch of Nasa-Langley. Early determinations showed a clear reduction in non-visible damage for thin COPVs when partially pressurized rather than unpressurized. Literature searches on Thicker-wall COPVs revealed surface damage but clearly visible. Analysis of current Analytic modeling indicated that that current COPV models lacked sufficient thickness corrections to predict impact damage. After a comprehensive study of available published data and numerous numerical studies based on observed data from Langley, the analytic framework for modeling the behavior was determined lacking and both Poe and Bogan suggested any short term (3yr) result for Jove would be overly ambitious and emphasis should be placed on transverse shear moduli studies. Transverse shear moduli determination is relevant to the study of fatigue, fracture and aging effects in composite structures. Based on the techniques developed by Daniel & Tsai, Bogan and Gates determined to verify the results for K3B and 8320. A detailed analytic and experimental plan was established and carried out that included variations in layup, width, thickness, and length. As well as loading rate variations to determine effects and relaxation moduli. The additional axial loads during the torsion testing were studied as was the placement of gages along the composite specimen. Of the proposed tasks, all of tasks I and 2 were completed with presentations given at Langley, SEM conferences and ASME/AIAA conferences. Sensitivity issues with the technique associated with the use of servohydraulic test systems for applying the torsional load to the composite specimen limited the torsion range for predictable and repeatable transverse shear properties. Bogan and Gates determined to diverge on research efforts with Gates continuing the experimental testing at Langley and Bogan modeling the apparent non-linear behavior at low torque & angles apparent from the tests.

Designing of a Fleet-Leader Program for Carbon Composite Overwrapped Pressure Vessels

NASA Technical Reports Server (NTRS)

Murthy, Pappu L.N.; Phoenix, S. Leigh

2009-01-01

Composite Overwrapped Pressure Vessels (COPVs) are often used for storing pressurant gases on board spacecraft when mass saving is a prime requirement. Substantial weight savings can be achieved compared to all metallic pressure vessels. For example, on the space shuttle, replacement of all metallic pressure vessels with Kevlar COPVs resulted in a weight savings of about 30 percent. Mass critical space applications such as the Ares and Orion vehicles are currently being planned to use as many COPVs as possible in place of all-metallic pressure vessels to minimize the overall mass of the vehicle. Due to the fact that overwraps are subjected to sustained loads during long periods of a mission, stress rupture failure is a major concern. It is, therefore, important to ascertain the reliability of these vessels by analysis, since it is practically impossible to show by experimental testing the reliability of flight quality vessels. Also, it is a common practice to set aside flight quality vessels as "fleet leaders" in a test program where these vessels are subjected to slightly accelerated operating conditions so that they lead the actual flight vessels both in time and load. The intention of fleet leaders is to provide advanced warning if there is a serious design flaw in the vessels so that a major disaster in the flight vessels can be averted with advance warning. On the other hand, the accelerating conditions must be not so severe as to be prone to false alarms. The primary focus of the present paper is to provide an analytical basis for designing a viable fleet leader program for carbon COPVs. The analysis is based on a stress rupture behavior model incorporating Weibull statistics and power-law sensitivity of life to fiber stress level.

Nondestructive Methods and Special Test Instrumentation Supporting NASA Composite Overwrapped Pressure Vessel Assessments

NASA Technical Reports Server (NTRS)

Saulsberry, Regor; Greene, Nathanael; Cameron, Ken; Madaras, Eric; Grimes-Ledesma, Lorie; Thesken, John; Phoenix, Leigh; Murthy, Pappu; Revilock, Duane

2007-01-01

Many aging composite overwrapped pressure vessels (COPVs), being used by the National Aeronautics and Space Administration (NASA) are currently under evaluation to better quantify their reliability and clarify their likelihood of failure due to stress rupture and age-dependent issues. As a result, some test and analysis programs have been successfully accomplished and other related programs are still in progress at the NASA Johnson Space Center (JSC) White Sands Test Facility (WSTF) and other NASA centers, with assistance from the commercial sector. To support this effort, a group of Nondestructive Evaluation (NDE) experts was assembled to provide NDE competence for pretest evaluation of test articles and for application of NDE technology to real-time testing. Techniques were required to provide assurance that the test article had adequate structural integrity and manufacturing consistency to be considered acceptable for testing and these techniques were successfully applied. Destructive testing is also being accomplished to better understand the physical and chemical property changes associated with progression toward "stress rupture" (SR) failure, and it is being associated with NDE response, so it can potentially be used to help with life prediction. Destructive work also includes the evaluation of residual stresses during dissection of the overwrap, laboratory evaluation of specimens extracted from the overwrap to evaluate physical property changes, and quantitative microscopy to inform the theoretical micromechanics.

Use of Modal Acoustic Emission to Monitor Damage Progression in Carbon Fiber/Epoxy and Implications for Composite Structures

NASA Technical Reports Server (NTRS)

Waller, J. M.; Nichols, C. T.; Wentzel, D. J.; Saulsberry R. L.

2010-01-01

Broad-band modal acoustic emission (AE) data was used to characterize micromechanical damage progression in uniaxial IM7 and T1000 carbon fiber-epoxy tows and an IM7 composite overwrapped pressure vessel (COPV) subjected to an intermittent load hold tensile stress profile known to activate the Felicity ratio (FR). Damage progression was followed by inspecting the Fast Fourier Transforms (FFTs) associated with acoustic emission events. FFT analysis revealed the occurrence of cooperative micromechanical damage events in a frequency range between 100 kHz and 1 MHz. Evidence was found for the existence of a universal damage parameter, referred to here as the critical Felicity ratio, or Felicity ratio at rupture (FR*), which had a value close to 0.96 for the tows and the COPV tested. The implications of using FR* to predict failure in carbon/epoxy composite materials and related composite components such as COPVs are discussed. Trends in the FFT data are also discussed; namely, the difference between the low and high energy events, the difference between early and late-life events, comparison of IM7 and T1000 damage progression, and lastly, the similarity of events occurring at the onset of significant acoustic emission used to calculate the FR.

Optical Sensing using Fiber Bragg Gratings for Monitoring Structural Damage in Composite Over-Wrapped Vessels

NASA Technical Reports Server (NTRS)

Grant, Joseph

2005-01-01

Composite Over-Wrap Vessels are widely used in the aerospace community. They are made of thin-walled bottles that are over wrapped with high strength fibers embedded in a matrix material. There is a strong drive to reduce the weight of space borne vehicles and thus pushes designers to adopt COPVs that are over wrapped with graphite fibers embedded in its epoxy matrix. Unfortunately, this same fiber-matrix configuration is more susceptible to impact damage than others and to make matters worse; there is a regime where impacts that damage the over wrap leave no visible scar on the COPV surface. In this paper FBG sensors are presented as a means of monitoring and detecting these types of damage. The FBG sensors are surface mounted to the COPVs and optically interrogated to explore the structural properties of these composite pressure vessels. These gratings optically inscribed into the core of a single mode fiber are used as a tool to monitor the stress strain relation in the composite matrix. The response of these fiber-optic sensors is investigated by pressurizing the cylinder up to its burst pressure of around 4500 psi. A Fiber Optic Demodulation System built by Blue Road Research, is used for interrogation of the Bragg gratings.

Use of Modal Acoustic Emission to Monitor Damage Progression in Carbon Fiber/Epoxy Tows and Implications for Composite Structures

NASA Technical Reports Server (NTRS)

Waller, Jess M.; Saulsberry, Regor L.; Lucero, Ralph; Nichols, Charles T.; Wentzel, Daniel J.

2010-01-01

ASTM-based ILH methods were found to give a reproducible, quantitative estimate of the stress threshold at which significant accumulated damage began to occur. a) FR events are low energy (<2 V(exp 20 microsec) b) FR events occur close to the observed failure locus. c) FR events consist of more than 30% fiber breakage (>300 kHz) d) FR events show a consistent hierarchy of cooperative damage for composite tow, and for the COPV tested, regardless of applied load. Application of ILH or related stress profiles could lead to robust pass/fail acceptance criteria based on the FR. Initial application of FR and FFT analysis of AE data acquired on COPVs is promising.

Structural Integrity of Gas-Filled Composite Overwrapped Pressure Vessels Subjected to Orbital Debris Impact

NASA Astrophysics Data System (ADS)

Telichev, Igor; Cherniaev, Aleksandr

Gas-filled pressure vessels are extensively used in spacecraft onboard systems. During operation on the orbit they exposed to the space debris environment. Due to high energies they contain, pressure vessels have been recognized as the most critical spacecraft components requiring protection from orbital debris impact. Major type of pressurized containers currently used in spacecraft onboard systems is composite overwrapped pressure vessels (COPVs) manufactured by filament winding. In the present work we analyze the structural integrity of vessels of this kind in case of orbital debris impact at velocities ranging from 2 to 10 km/s. Influence of such parameters as projectile energy, shielding standoff, internal pressure and filament winding pattern on COPVs structural integrity has been investigated by means of numerical and physical experiments.

An Overview of the Space Shuttle Orbiter's Aging Aircraft Program

NASA Technical Reports Server (NTRS)

Russell, Richard W.

2007-01-01

The Space Shuttle Orbiter has well exceeded its original design life of 10 years or 100 missions. The Orbiter Project Office (OPO) has sponsored several activities to address aging vehicle concerns, including a Corrosion Control Review Board (CCRB), a mid-life certification program, and most recently the formation of the Aging Orbiter Working Group (AOWG). The AOWG was chartered in 2004 as a proactive group which provides the OPO oversight for aging issues such as corrosion, non-destructive inspection, non-metallics, wiring and subsystems. The core team consists of mainly representatives from the Materials and Processes Problem Resolution Team (M&P PRT) and Safety and Mission Assurance (S&MA). Subsystem engineers and subject matter experts are called in as required. The AOWG has functioned by forming issues based sub-teams. Examples of completed sub-teams include adhesives, wiring and wing leading edge metallic materials. Current sub-teams include Composite Over-Wrapped Pressure Vessels (COPV), elastomeric materials and mechanisms.

Reliability of COPVs Accounting for Margin of Safety on Design Burst

NASA Technical Reports Server (NTRS)

Murthy, Pappu L.N.

2012-01-01

In this paper, the stress rupture reliability of Carbon/Epoxy Composite Overwrapped Pressure Vessels (COPVs) is examined utilizing the classic Phoenix model and accounting for the differences between the design and the actual burst pressure, and the liner contribution effects. Stress rupture life primarily depends upon the fiber stress ratio which is defined as the ratio of stress in fibers at the maximum expected operating pressure to actual delivered fiber strength. The actual delivered fiber strength is calculated using the actual burst pressures of vessels established through burst tests. However, during the design phase the actual burst pressure is generally not known and to estimate the reliability of the vessels calculations are usually performed based upon the design burst pressure only. Since the design burst is lower than the actual burst, this process yields a much higher value for the stress ratio and consequently a conservative estimate for the reliability. Other complications arise due to the fact that the actual burst pressure and the liner contributions have inherent variability and therefore must be treated as random variables in order to compute the stress rupture reliability. Furthermore, the model parameters, which have to be established based on stress rupture tests of subscale vessels or coupons, have significant variability as well due to limited available data and hence must be properly accounted for. In this work an assessment of reliability of COPVs including both parameter uncertainties and physical variability inherent in liner and overwrap material behavior is made and estimates are provided in terms of degree of uncertainty in the actual burst pressure and the liner load sharing.

A Critique of a Phenomenological Fiber Breakage Model for Stress Rupture of Composite Materials

NASA Technical Reports Server (NTRS)

Reeder, James R.

2010-01-01

Stress rupture is not a critical failure mode for most composite structures, but there are a few applications where it can be critical. One application where stress rupture can be a critical design issue is in Composite Overwrapped Pressure Vessels (COPV's), where the composite material is highly and uniformly loaded for long periods of time and where very high reliability is required. COPV's are normally required to be proof loaded before being put into service to insure strength, but it is feared that the proof load may cause damage that reduces the stress rupture reliability. Recently, a fiber breakage model was proposed specifically to estimate a reduced reliability due to proof loading. The fiber breakage model attempts to model physics believed to occur at the microscopic scale, but validation of the model has not occurred. In this paper, the fiber breakage model is re-derived while highlighting assumptions that were made during the derivation. Some of the assumptions are examined to assess their effect on the final predicted reliability.

Online Damage Detection on Metal and Composite Space Structures by Active and Passive Acoustic Methods

NASA Astrophysics Data System (ADS)

Scheerer, M.; Cardone, T.; Rapisarda, A.; Ottaviano, S.; Ftancesconi, D.

2012-07-01

In the frame of ESA funded programme Future Launcher Preparatory Programme Period 1 “Preparatory Activities on M&S”, Aerospace & Advanced Composites and Thales Alenia Space-Italia, have conceived and tested a structural health monitoring approach based on integrated Acoustic Emission - Active Ultrasound Damage Identification. The monitoring methods implemented in the study are both passive and active methods and the purpose is to cover large areas with a sufficient damage size detection capability. Two representative space sub-structures have been built and tested: a composite overwrapped pressure vessel (COPV) and a curved, stiffened Al-Li panel. In each structure, typical critical damages have been introduced: delaminations caused by impacts in the COPV and a crack in the stiffener of the Al-Li panel which was grown during a fatigue test campaign. The location and severity of both types of damages have been successfully assessed online using two commercially available systems: one 6 channel AE system from Vallen and one 64 channel AU system from Acellent.

Ten Problems in Artificial Intelligence.

DTIC Science & Technology

1987-01-01

22217 Computer Systems Management , Inc. 5 copies 130o Wilson Boulevard, Suite 102 % Arlington, Virginia 22209 Ms. Robin D)illard cop)v Naval Ocean...old ones lightlY inl order to fit ne.w data. A good model for thi-s kind ,)f knowlede t riicture re.vi-in is XllaIi.tit. Xhen, people have a predlictiv

A Comparison of Various Stress Rupture Life Models for Orbiter Composite Pressure Vessels and Confidence Intervals

NASA Technical Reports Server (NTRS)

Grimes-Ledesma, Lorie; Murthy, Pappu L. N.; Phoenix, S. Leigh; Glaser, Ronald

2007-01-01

In conjunction with a recent NASA Engineering and Safety Center (NESC) investigation of flight worthiness of Kevlar Overwrapped Composite Pressure Vessels (COPVs) on board the Orbiter, two stress rupture life prediction models were proposed independently by Phoenix and by Glaser. In this paper, the use of these models to determine the system reliability of 24 COPVs currently in service on board the Orbiter is discussed. The models are briefly described, compared to each other, and model parameters and parameter uncertainties are also reviewed to understand confidence in reliability estimation as well as the sensitivities of these parameters in influencing overall predicted reliability levels. Differences and similarities in the various models will be compared via stress rupture reliability curves (stress ratio vs. lifetime plots). Also outlined will be the differences in the underlying model premises, and predictive outcomes. Sources of error and sensitivities in the models will be examined and discussed based on sensitivity analysis and confidence interval determination. Confidence interval results and their implications will be discussed for the models by Phoenix and Glaser.

Smart Composite Overwrapped Pressure Vessel - Integrated Structural Health Monitoring System to Meet Space Exploration and International Space Station Mission Assurance Needs

NASA Technical Reports Server (NTRS)

Saulsberry, Regor; Nichols, Charles; Waller, Jess

2012-01-01

Currently there are no integrated NDE methods for baselining and monitoring defect levels in fleet for Composite Overwrapped Pressure Vessels (COPVs) or related fracture critical composites, or for performing life-cycle maintenance inspections either in a traditional remove-and-inspect mode or in a more modern in situ inspection structural health monitoring (SHM) mode. Implicit in SHM and autonomous inspection is the existence of quantitative accept-reject criteria. To be effective, these criteria must correlate with levels of damage known to cause composite failure. Furthermore, implicit in SHM is the existence of effective remote sensing hardware and automated techniques and algorithms for interpretation of SHM data. SHM of facture critical composite structures, especially high pressure COPVs, is critical to the success of nearly every future NASA space exploration program as well as life extension of the International Space Station. It has been clearly stated that future NASA missions may not be successful without SHM [1]. Otherwise, crews will be busy addressing subsystem health issues and not focusing on the real NASA mission

Research and Development of Automated Eddy Current Testing for Composite Overwrapped Pressure Vessels

NASA Technical Reports Server (NTRS)

Carver, Kyle L.; Saulsberry, Regor L.; Nichols, Charles T.; Spencer, Paul R.; Lucero, Ralph E.

2012-01-01

Eddy current testing (ET) was used to scan bare metallic liners used in the fabrication of composite overwrapped pressure vessels (COPVs) for flaws which could result in premature failure of the vessel. The main goal of the project was to make improvements in the areas of scan signal to noise ratio, sensitivity of flaw detection, and estimation of flaw dimensions. Scan settings were optimized resulting in an increased signal to noise ratio. Previously undiscovered flaw indications were observed and investigated. Threshold criteria were determined for the system software's flaw report and estimation of flaw dimensions were brought to an acceptable level of accuracy. Computer algorithms were written to import data for filtering and a numerical derivative filtering algorithm was evaluated.

New ASTM Standards for Nondestructive Testing of Aerospace Composites

NASA Technical Reports Server (NTRS)

Waller, Jess M.; Saulsberry, Regor L.

2010-01-01

Problem: Lack of consensus standards containing procedural detail for NDE of polymer matrix composite materials: I. Flat panel composites. II. Composite components with more complex geometries a) Pressure vessels: 1) composite overwrapped pressure vessels (COPVs). 2) composite pressure vessels (CPVs). III. Sandwich core constructions. Metal and brittle matrix composites are a possible subject of future effort.

Altered postural control variability in older-aged individuals with a history of lateral ankle sprain.

PubMed

Terada, Masafumi; Kosik, Kyle; Johnson, Nathan; Gribble, Phillip

2018-02-01

The current study aimed to examine postural control performance during a single-leg balance task in elderly individuals with and without a previous history of lateral ankle sprain (LAS). Eighteen adults with a previous history of LAS (mean age = 66 years old) and 12 healthy controls (mean age = 65 years old) were included in the study. Participants performed three trials of a single-leg balance task during an eyes-opened condition for 20-s. Center of pressure (COP) trajectories in the anteroposterior (AP) and mediolateral (ML) directions were collected with a force plate. The following postural control measures were calculated in the AP and ML directions: 1) Sample Entropy (SampEn); 2) Approximate Entropy (ApEn); 3) mean of Time-to-Boundary minima (mean TTB); and 4) COP velocity (COPV). Older-age participants with a history LAS exhibited lower ApEn-AP, SampEn-AP, and SampEn-ML values compared to healthy controls (p < 0.05). The information gained from this investigation indicates more rigid postural control patterns, less adaptability, and more difficulty maintaining COP during a single-leg balance task in adults with a previous history of LAS. Our data suggest that there is a need to consider history of musculoskeletal injury when evaluating factors for postural control and fall risk in the elderly. Future investigations are needed to assess the effect of LAS on age-related declines in postural control and discern associations between potential risk factors of fall-related injuries and LAS in an elderly population. Copyright © 2017 Elsevier B.V. All rights reserved.

Composite Stress Rupture: A New Reliability Model Based on Strength Decay

NASA Technical Reports Server (NTRS)

Reeder, James R.

2012-01-01

A model is proposed to estimate reliability for stress rupture of composite overwrap pressure vessels (COPVs) and similar composite structures. This new reliability model is generated by assuming a strength degradation (or decay) over time. The model suggests that most of the strength decay occurs late in life. The strength decay model will be shown to predict a response similar to that predicted by a traditional reliability model for stress rupture based on tests at a single stress level. In addition, the model predicts that even though there is strength decay due to proof loading, a significant overall increase in reliability is gained by eliminating any weak vessels, which would fail early. The model predicts that there should be significant periods of safe life following proof loading, because time is required for the strength to decay from the proof stress level to the subsequent loading level. Suggestions for testing the strength decay reliability model have been made. If the strength decay reliability model predictions are shown through testing to be accurate, COPVs may be designed to carry a higher level of stress than is currently allowed, which will enable the production of lighter structures

DebriSat Laboratory Analyses

DTIC Science & Technology

2015-01-05

droplets. Fluorine from Teflon wire insulation was also common in the SEM stub and witness plates deposits. Nano droplets of metallic materials...and Debris-LV debris. Aluminum was from the Al honeycomb, nadir and zenith panels, structural core and COPV liner. Aluminum oxide particles were...three pieces: Outer Nylon shell (sabot) with 2 part hollow aluminum insert. • ~600 grams, 8.6 cm diameter X 10.3 cm long – size of a soup can

Strain Measurement during Stress Rupture of Composite Over-Wrapped Pressure Vessel with Fiber Bragg Gratings Sensors

NASA Technical Reports Server (NTRS)

Banks, Curtis E.; Grant, Joseph; Russell, Sam; Arnett, Shawn

2008-01-01

Fiber optic Bragg gratings were used to measure strain fields during Stress Rupture (SSM) test of Kevlar Composite Over-Wrapped Pressure Vessels (COPV). The sensors were embedded under the over-wrapped attached to the liner released from the Kevlar and attached to the Kevlar released from the liner. Additional sensors (foil gages and fiber bragg gratings) were surface mounted on the COPY liner.

[Relationship between unipedal stance test score and center of pressure velocity in elderly].

PubMed

Rodrigo Antonio, Guzmán; Rony, Silvestre; Francisco Aniceto, Rodríguez; David Andrés, Arriagada; Pablo Andrés, Ortega

2011-01-01

Frequent falls are one of the most important health problems in the elderly population. The unipedal stance test (UPST), asses postural stability and is used in fall risk measures. Despite this, there is little information about its relationship with posturographic parameters (PP) that characterizes postural stability. Center of pressure velocity (CoPV) is one of the best PP that describes postural stability. The aim of this study was to analyze the relation between UST score and CoPV in elderly population. A sample of 38 healthy elderly subjects where divided in two groups according to their UPST score, low performance (LP, n=11) and high performance (HP, n=27). The correlation between UPST score and COP mean velocity (CoPmV), recorded from a posturographic test, was analyzed between both groups. An inverse correlation between UPST score and CoPmV was found in both groups. However, this was higher in the LP group (r=-0.69, P=.02) compared to the HP (r=-0.39, P=.04). Based on the results of this investigation, it may be concluded that the achievement on UPST has an inverse relationship with CoPmV, especially in subjects with low performance in the UPST. Copyright © 2010 SEGG. Published by Elsevier Espana. All rights reserved.

Strength, Fatigue, and Fracture Toughness of Ti-6Al-4V Liner from a Composite Over-Wrapped Pressure Vessel

NASA Technical Reports Server (NTRS)

Salem, Jonathan A.; Lerch, Brad; Thesken, John C.; Sutter, Jim; Russell, Richard

2008-01-01

It was demonstrated by way of experiment that Composite Over-wrapped Pressure Vessel (COPV) Ti-6Al-4V liner material can sustain the expected service loads and cycles. The experiments were performed as part of investigations on the residual life of COPV tanks being used in Space Shuttle Orbiters. Measured properties included tensile strength, compressive strength, reversed loading cycles to simulate liner proof strains, and cyclic fatigue loading to demonstrate the ability to sustain 1000 cycles after liner buckling. The liner material came from a salvaged 40 in. Columbia (orbiter 102) tank (SN029), and tensile strength measurements were made on both boss-transition (thick) and membrane regions (thin). The average measured yield strength was 131 ksi in the boss-transition and membrane regions, in good agreement with measurements made on 1970 s vintage forged plate stock. However, Young s modulus was 17.4+/-0.3 Msi, somewhat higher than typical handbook values (approx.16 Msi). The fracture toughness, as estimated from a failed fatigue specimen, was 74 ksi/sq in, in reasonable agreement with standardized measurements made on 1970 s vintage forged plate stock. Low cycle fatigue of a buckled test specimen implied that as-imprinted liners can sustain over 4000 load cycles.

Battlefield Management System: Data Requirements to Support Passage of Company Level Tactical Information.

DTIC Science & Technology

1987-03-01

intelligent way, assemble those documents and data in usable formats, examine the communications tapes available for this project, and to develop a sampling...Lifetime Learning Publications, Belmont. CA. 1982. Rowe. Neil C.. Artifcial Intelligence , Draft Copv, Class Notes for Winter Quarter. CS 33 10, \\aval...AT2 122 BATTLEFIELD MANAGEMENT SYSTEM DATA REQUIRENTS TO 1/2 SUPPORT PASSAGE OF COMPANY LEVEL TACTICAL INFORMATION (U) NVALE POSTGRADUATE SCHOOL

Modeling ARRM Xenon Tank Pressurization Using 1D Thermodynamic and Heat Transfer Equations

NASA Technical Reports Server (NTRS)

Gilligan, Patrick; Tomsik, Thomas

2016-01-01

As a first step in understanding what ground support equipment (GSE) is required to provide external cooling during the loading of 5,000 kg of xenon into 4 aluminum lined composite overwrapped pressure vessels (COPVs), a modeling analysis was performed using Microsoft Excel. The goals of the analysis were to predict xenon temperature and pressure throughout loading at the launch facility, estimate the time required to load one tank, and to get an early estimate of what provisions for cooling xenon might be needed while the tanks are being filled. The model uses the governing thermodynamic and heat transfer equations to achieve these goals. Results indicate that a single tank can be loaded in about 15 hours with reasonable external coolant requirements. The model developed in this study was successfully validated against flight and test data. The first data set is from the Dawn mission which also utilizes solar electric propulsion with xenon propellant, and the second is test data from the rapid loading of a hydrogen cylindrical COPV. The main benefit of this type of model is that the governing physical equations using bulk fluid solid temperatures can provide a quick and accurate estimate of the state of the propellant throughout loading which is much cheaper in terms of computational time and licensing costs than a Computation Fluid Dynamics (CFD) analysis while capturing the majority of the thermodynamics and heat transfer.

Modeling Xenon Tank Pressurization using One-Dimensional Thermodynamic and Heat Transfer Equations

NASA Technical Reports Server (NTRS)

Gilligan, Ryan P.; Tomsik, Thomas M.

2017-01-01

As a first step in understanding what ground support equipment (GSE) is required to provide external cooling during the loading of 5,000 kg of xenon into 4 aluminum lined composite overwrapped pressure vessels (COPVs), a modeling analysis was performed using Microsoft Excel. The goals of the analysis were to predict xenon temperature and pressure throughout loading at the launch facility, estimate the time required to load one tank, and to get an early estimate of what provisions for cooling xenon might be needed while the tanks are being filled. The model uses the governing thermodynamic and heat transfer equations to achieve these goals. Results indicate that a single tank can be loaded in about 15 hours with reasonable external coolant requirements. The model developed in this study was successfully validated against flight and test data. The first data set is from the Dawn mission which also utilizes solar electric propulsion with xenon propellant, and the second is test data from the rapid loading of a hydrogen cylindrical COPV. The main benefit of this type of model is that the governing physical equations using bulk fluid solid temperatures can provide a quick and accurate estimate of the state of the propellant throughout loading which is much cheaper in terms of computational time and licensing costs than a Computation Fluid Dynamics (CFD) analysis while capturing the majority of the thermodynamics and heat transfer.

The 2012-2014 eruptive cycle of Copahue Volcano, Southern Andes. Magmatic-Hydrothermal system interaction and manifestations.

NASA Astrophysics Data System (ADS)

Morales, Sergio; Alarcón, Alex; Basualto, Daniel; Bengoa, Cintia; Bertín, Daniel; Cardona, Carlos; Córdova, Maria; Franco, Luis; Gil, Fernando; Hernandez, Erasmo; Lara, Luis; Lazo, Jonathan; Mardones, Cristian; Medina, Roxana; Peña, Paola; Quijada, Jonathan; San Martín, Juan; Valderrama, Oscar

2015-04-01

Copahue Volcano (COPV), in Southern Andes of Chile, is an andesitic-basaltic stratovolcano, which is located on the western margin of Caviahue Caldera. The COPV have a NE-trending fissure with 9 aligned vents, being El Agrio the main currently active vent, with ca. 400 m in diameter. The COPV is placed into an extensive hydrothermal system which has modulated its recent 2012-2014 eruptive activity, with small phreatic to phreatomagmatic eruptions and isolated weak strombolian episodes and formation of crater lakes inside the main crater. Since 2012, the Southern Andes Volcano Observatory (OVDAS) carried out the real-time monitoring with seismic broadband stations, GPS, infrasound sensors and webcams. In this work, we report pre, sin, and post-eruptive seismic activity of the last two main eruptions (Dec, 2012 and Oct, 2014) both with different seismic precursors and superficial activity, showing the second one a particularly appearance of seismic quiescence episodes preceding explosive activity, as an indicator of interaction between magmatic-hydrothermal systems. The first episode, in late 2012, was characterized by a low frequency (0.3-0.4 Hz and 1.0-1.5 Hz) continuous tremor which increased gradually from background noise level amplitude to values of reduced displacement (DR), close to 50 cm2 at the peak of the eruption, reaching an eruptive column of ~1.5 km height. After few months of recording low energy seismicity, a sequence of low frequency, repetitive and low energy seismic events arose, with a frequency of occurrence up to 300 events/hour. Also, the VLP earthquakes were added to the record probably associated with magma intrusion into a deep magmatic chamber during all stages of eruptive process, joined to the record of VT seismicity during the same period, which is located throughout the Caviahue Caldera area. Both kind of seismic patterns were again recorded in October 2014, being the precursor of the new eruptive cycle at this time as well as the deformation of the volcanic edifice detected by GPS network. In this new eruptive process, the record of tremor was followed by particular seismic quiescence, as precursors of explosive activity which evolved from low acoustic energy signals toward more energetic signals with impulsive first arrivals and strong attenuation, joined to night incandescence in the main vent without evident juvenile material ejected, which could be associated to the temporal depression of the hydrothermal system located in the volcano system. The recent eruptive episode at Copahue Volcano is a good example of the complex temporal evolution of the interaction between magmatic and hydrothermal systems.

Ada Compiler Validation Summary Report. Certificate Number 880728S1. 09141 DDC-I, Inc., DACS-386/UNIX, Version 4.2, ICL DRS 300 Host and Target

DTIC Science & Technology

1988-07-28

r R ~l~ F COPV en Data Entered) AT ION PAGE -ErOP RCoMrE-EoNGFOP. A D-A 204 928 1Z. GOVT ACCESSION NO. 3. RECIPIENT’S CATALOG NUMBER 4...PAGE (When Data Entered) Ada Compiler Validation Summary Repor-: Compiler Name: DACS-386/UNIX, Version 4.2 Certificate Number: 880728S1.09141 Host...which have the STORAGE SIZE length clause were changed to comment lines under the direction of the AVF Manager . These modified tests ran to a successful

Stress Rupture Testing and Analysis of the NASA WSTF-JPL Carbon Overwrapped Pressure Vessels

NASA Technical Reports Server (NTRS)

Greene, Nathanael; Yoder, Tommy; Saulsberry, Regor; Grimes, Lorie; Thesken, John; Phoenix, Leigh

2007-01-01

Carbon composite overwrapped pressure vessels (COPVs) are widely used in applications from spacecraft to life support. COPV technology provides a pressurized media storage advantage over amorphous technology with weight savings on the order of 30 percent. The National Aeronautics and Space Administration (NASA) has been supporting the development of this technology since the early 1970's with an interest in safe application of these components to reduce mass to orbit. NASA White Sands Test Facility (WSTF) has been testing components in support of this objective since the 1980s and has been involved in test development and analysis to address affects of impact, propellant and cryogenic fluids exposure on Kevlar and carbon epoxy. The focus of this paper is to present results of a recent joint WSTF-Jet Propulsion Laboratories (JPL) effort to assess safe life of these components. The WSTF-JPL test articles consisted of an aluminum liner and a carbon fiber overwrap in an industry standard epoxy resin system. The vessels were specifically designed with one plus-minus helical wrap and one hoop wrap over the helical and they measured 4.23 x 11.4 in. long. 120 test articles were manufactured in August of 1998 of one lot fiber and resin and the 110 test articles were delivered to WSTF for test. Ten of the 120 test articles were burst tested at the manufacturer to establish the delivered fiber stress. Figure 1 shows a test article in a pre burst condition and with a hoop fiber failure (no leak of pressurized media) and post burst (failure of liner and loss of pressurized media).

Attention is associated with postural control in those with chronic ankle instability.

PubMed

Rosen, Adam B; Than, Nicholas T; Smith, William Z; Yentes, Jennifer M; McGrath, Melanie L; Mukherjee, Mukul; Myers, Sara A; Maerlender, Arthur C

2017-05-01

Chronic ankle instability (CAI) is often debilitating and may be affected by a number of intrinsic and environmental factors. Alterations in neurocognitive function and attention may contribute to repetitive injury in those with CAI and influence postural control strategies. Thus, the purpose of this study was to determine if there was a difference in attentional functioning and static postural control among groups of Comparison, Coper and CAI participants and assess the relationship between them within each of the groups. Recruited participants performed single-limb balance trials and completed the CNS Vital Signs (CNSVS) computer-based assessment to assess their attentional function. Center of pressure (COP) velocity (COPv) and maximum range (COPr), in both the anteroposterior (AP) and mediolateral (ML) directions were calculated from force plate data. Simple attention (SA), which measures self-regulation and attention control was extracted from the CNSVS. Data from 45 participants (15 in each group, 27=female, 18=male) was analyzed for this study. No significant differences were observed between attention or COP variables among each of the groups. However, significant relationships were present between attention and COP variables within the CAI group. CAI participants displayed significant moderate to large correlations between SA and AP COPr (r=-0.59, p=0.010), AP COPv (r=-0.48, p=0.038) and ML COPr (r=-0.47, p=0.034). The results suggest a linear relationship of stability and attention in the CAI group. Attentional self-regulation may moderate how those with CAI control postural stability. Incorporating neurocognitive training focused on attentional control may improve outcomes in those with CAI. Copyright © 2017 Elsevier B.V. All rights reserved.

Structural CNT Composites Part II: Assessment of CNT Yarns as Reinforcement for Composite Overwrapped Pressure Vessels

NASA Technical Reports Server (NTRS)

Kim, Jae-Woo; Sauti, Godfrey; Cano, Roberto J.; Wincheski, Russell A.; Ratcliffe, James G.; Czabaj, Michael; Siochi, Emilie J.

2015-01-01

Carbon nanotubes (CNTs) are one-dimensional nanomaterials with outstanding electrical and thermal conductivities and mechanical properties. This combination of properties offers routes to enable lightweight structural aerospace components. Recent advances in the manufacturing of CNTs have made bulk forms such as yarns, tapes and sheets available in commercial quantities to permit the evaluation of these materials for aerospace use, where the superior tensile properties of CNT composites can be exploited in tension dominated applications such as composite overwrapped pressure vessels (COPVs). To investigate their utility in this application, aluminum rings were overwrapped with thermoset/CNT yarn composite and their mechanical properties measured. CNT composite overwrap characteristics such as processing method, CNT/resin ratio, and applied tension during CNT yarn winding were varied to determine their effects on the mechanical performance of the CNT composite overwrapped Al rings (CCOARs). Mechanical properties of the CCOARs were measured under static and cyclic loads at room, elevated, and cryogenic temperatures to evaluate their mechanical performance relative to bare Al rings. At room temperature, the breaking load of CCOARs with a 10.8% additional weight due to the CNT yarn/thermoset overwrap increased by over 200% compared to the bare Al ring. The quality of the wound CNT composites was also investigated using x-ray computed tomography.

Nanotechnology

NASA Technical Reports Server (NTRS)

Biaggi-Labiosa, Azlin

2016-01-01

Present an overview of the Nanotechnology Project at NASA's Game Changing Technology Industry Day. Mature and demonstrate flight readiness of CNT reinforced composites for future NASA mission applications?Sounding rocket test in a multiexperiment payload?Integrate into cold gas thruster system as propellant storage?The technology would provide the means for reduced COPV mass and improved damage tolerance and flight qualify CNT reinforced composites. PROBLEM/NEED BEING ADDRESSED:?Reduce weight and enhance the performance and damage tolerance of aerospace structuresGAME-CHANGING SOLUTION:?Improve mechanical properties of CNTs to eventually replace CFRP –lighter and stronger?First flight-testing of a CNT reinforced composite structural component as part of an operational flight systemUNIQUENESS:?CNT manufacturing methods developed?Flight qualify CNT reinforced composites

IPHE Regulations Codes and Standards Working Group - Type IV COPV Round Robin Testing

NASA Technical Reports Server (NTRS)

Maes, M.; Starritt, L.; Zheng, J. Y.; Ou, K.; Keller, J.

2017-01-01

This manuscript presents the results of a multi-lateral international activity intended to understand how to execute a cycle stress test as specified in a chosen standard (GTR, SAE, ISO, EIHP...). The purpose of this work was to establish a harmonized test method protocol to ensure that the same results would be achieved regardless of the testing facility. It was found that accurate temperature measurement of the working fluid is necessary to ensure the test conditions remain within the tolerances specified. Continuous operation is possible with adequate cooling of the working fluid but this becomes more demanding if the cycle frequency increases. Recommendations for future test system design and operation are presented.

The Inclusion of Arbitrary Load Histories in the Strength Decay Model for Stress Rupture

NASA Technical Reports Server (NTRS)

Reeder, James R.

2014-01-01

Stress rupture is a failure mechanism where failures can occur after a period of time, even though the material has seen no increase in load. Carbon/epoxy composite materials have demonstrated the stress rupture failure mechanism. In a previous work, a model was proposed for stress rupture of composite overwrap pressure vessels (COPVs) and similar composite structures based on strength degradation. However, the original model was limited to constant load periods (holds) at constant load. The model was expanded in this paper to address arbitrary loading histories and specifically the inclusions of ramp loadings up to holds and back down. The broadening of the model allows for failures on loading to be treated as any other failure that may occur during testing instead of having to be treated as a special case. The inclusion of ramps can also influence the length of the "safe period" following proof loading that was previously predicted by the model. No stress rupture failures are predicted in a safe period because time is required for strength to decay from above the proof level to the lower level of loading. Although the model can predict failures during the ramp periods, no closed-form solution for the failure times could be derived. Therefore, two suggested solution techniques were proposed. Finally, the model was used to design an experiment that could detect the difference between the strength decay model and a commonly used model for stress rupture. Although these types of models are necessary to help guide experiments for stress rupture, only experimental evidence will determine how well the model may predict actual material response. If the model can be shown to be accurate, current proof loading requirements may result in predicted safe periods as long as 10(13) years. COPVs design requirements for stress rupture may then be relaxed, allowing more efficient designs, while still maintaining an acceptable level of safety.

Develop Critical Profilometers to Meet Current and Future Composite Overwrapped Pressure Vessel (COPV) Interior Inspection Needs

NASA Technical Reports Server (NTRS)

Saulsberry, Regor L.

2010-01-01

The objective of this project is to develop laser profilometer technology that can efficiently inspect and map the inside of composite pressure vessels for flaws such as liner buckling, pitting, or other surface imperfections. The project will also provide profilometers that can directly support inspections of flight vessels during development and qualification programs and subsequently be implemented into manufacturing inspections to screen out vessels with "out of family" liner defects. An example interior scan of a carbon overwrapped bottle is shown in comparison to an external view of the same bottle (Fig. 1). The internal scan is primarily of the cylindrical portion, but extends about 0.15 in. into the end cap area.

Acoustic Emission Health Monitoring of Fill Purge COPV's Used in Aerospace and Automotive Applications and Designed for Long Cycle Life

NASA Technical Reports Server (NTRS)

Waller, Jess

2013-01-01

Cumulative composite damage in composite pressure vessels (CPVs) currently is not monitored on-orbit. Consequently, hazards due to catastrophic burst before leak (BBL) or compromised CPV reliability cannot be ascertained or mitigated, posing a risk to crew and mission assurance. The energy associated with CPV rupture can be significant, especially with high pressure gases are under containment, and the energy releases can be severe enough to cause injury, death, loss of assets or mission. Dual-Use Rationale: CPVs similar to those used by NASA on ISS, for example, are finding increasing use in automotive and transportation industry applications. These CPVs generally have a nonload sharing liner and are repeatedly filled over their service lifetime, typically with hydrogen or compressed natural gas (CNG). The same structural health monitoring equipment and software developed by NASA WSTF for evaluating, in real-time, the health of NASA CPVs on ISS will be used to evaluate the health of automotive CPVs, the only differences being the type and design of the CPV, and the in-service lifetime pressure histories. HSF Need(s)/Performance Characteristic(s) Supported: 1) Enable on-board vehicle systems management for mission critical functions at destinations with > 3 second time delay 2) Enable autonomous nominal operations and FDIR for crewed and un-crewed systems 3) Reduce on-board crew time to sustain and manage vehicle by factor of 2x at destinations with > 6 second time delay (see Crew Autonomy sheet) 4) Reduce earth-based mission ops "back room engineering" requirements for distant mission support delay (see Mission Autonomy sheet)

Material Usage in High Pressure Oxygen Systems for the International Space Station

NASA Technical Reports Server (NTRS)

Kravchenko, Michael; Sievers, D. Elliott

2014-01-01

The Nitrogen/Oxygen Recharge System (NORS) for the International Space Station (ISS) Program was required as part of the Space Shuttle retirement efforts to sustain the ISS life support systems. The system is designed around a 7000 psia Oxygen or Nitrogen Recharge Tank Assembly which is able to be utilized both internally and externally to the ISS. Material selection and usage were critical to ensure oxygen compatibility for the design, while taking into consideration toxicity, weldability, brazability and general fabrication and assembly techniques. The system uses unique hardware items such a composite overwrap pressure vessel (COPV), high pressure mechanical gauges, compact regulators and valves, quick disconnects, metal tubing and flexhoses. Numerous challenges and anomalies were encountered due to the exotic nature of this project which will be discussed in detail. The knowledge gained from these anomalies and failure resolutions can be applied to more than space applications, but can also be applicable to industry pressurized systems.

Analysis of Potential for Titanium Liner Buckling after Proof in a Large Kevlar/Epoxy COPV

NASA Technical Reports Server (NTRS)

Phoenix, S. Leigh; Kezirian, Michael T.

2009-01-01

We analyze the potential for liner buckling in a 40-in Kevlar49/epoxy overwrapped spherical pressure vessel (COPV) due to long, local depressions or valleys in the titanium liner, which appeared after proof testing (autofrettage). We begin by presenting the geometric characteristics of approximately 20 mil (0.02 in.) deep depressions measured by laser profilometry in several vessels. While such depths were more typical, depths of more than 40 mils (0.02 in.) were seen near the equator in one particular vessel. Such depressions are largely the result of overlap of the edges of overwrap bands (with rectangular cross-section prepreg tows) from the first or second wrap patterns particularly where they start and end. We then discuss the physical mechanisms of formation of the depressions during the autofrettage process in terms of uneven void compaction in the overwrap around the tow overlap lines and the resulting 10-fold increase in through-thickness stiffness of the overwrap. We consider the effects of liner plastic yielding mechanisms in the liner on residual bending moments and interface pressures with the overwrap both at the peak proof pressure (approx.6500 psi) and when reducing the pressure to 0 psi. During depressurization the Bauschinger phenomenon becomes very important whereby extensive yielding in tension reduces the magnitude of the yield threshold in compression by 30 to 40%, compared to the virgin annealed state of the liner titanium. In the absence of a depression, the liner is elastically stable in compression even at liner overwrap interface pressures nominally 6 times the approx. 1000 psi interface pressure that exists at 0 psi. Using a model based on a plate-on-an-elastic-foundation, we develop an extensive analysis of the possible destabilizing effects of a frozen-in valley. The analysis treats the modifying effects of the residual bending moments and interface pressures remaining after the proof hold as well as the Bauschinger effect on the compressive yield threshold. The key result is that depression depths of up to 40 mils can be tolerated, but above 40 mils, the Bauschinger effect drives destabilization, and buckling becomes increasingly likely depending on the details of depression formation during autofrettage. It is almost certain that destabilization and buckling will occur for depression depths beyond 55 mils. The main equations and formulas for treating the various phases of depression development and potential buckling, are only briefly outlined in the paper, but are available from the authors.

Analysis of concentration-dependent effects of copper and PCB on different Chattonella spp. microalgae (raphidophyceae) cultivated in artificial seawater medium

PubMed Central

Niestroy, Jeanette; Martínez, Alfonso Bárbara; Band-Schmidt, Christine J.

2014-01-01

In the present study, the effect on the chlorophyll a and the total protein content as well as the Chattonella spp. cell viability were examined after concentration-dependent exposure to CuCl2 and Aroclor 1242. The comparison between various raphidophyte strains provides an insight into the different susceptibilities to contaminants of Chattonella subsalsa (CSNAV-1), C. marina var. marina (CMCV-1) and C. marina var. ovata (COPV-2). The microalgae were cultivated in artificial seawater medium. Exponentially growing microalgae (8-10 days in culture) were used for exposure experiments. We observed in all three raphidophyte species cytotoxicity-mediated modifications beginning at concentrations of 150 and 200 µM of the heavy metal copper after 24 hours exposure. But interestingly, the three strains exhibited only slight differences in their susceptibility to CuCl2. C. subsalsa and C. marina var. marina cells were first affected at the chlorophyll a level and in cell viability. The total protein amount was reduced significantly only after exposure to 300 µM of CuCl2. However, C. marina var. ovata microalgae showed similar reduction curves for all three analysed cytotoxicity endpoints after heavy metal exposure. On the other hand, after Aroclor 1242 incubation the cytotoxic modification pattern indicated clearly the different susceptibilities of the three raphidophyte strains. C. subsalsa cells noticeably exhibited a decrease in the analysed pigment amount (30-20 % compared to that of the control) already after 0.007 mg/L PCB exposure. In contrast, cell viability and total protein content were slightly reduced and fell below the 50 % threshold after 0.7 and 3.3 mg/L of Aroclor 1242, respectively. Interestingly, C. marina var. ovata showed almost no cytotoxic modification caused by the PCB mixture. Only the concentration of 0.7 mg/L Aroclor 1242 clearly affected the cell viability. As opposed to that we observed a concentration-dependent decrease of cell viability and chlorophyll a amount in CMCV-1 microalgae. These observations confirmed that the susceptibility of the raphidophytes strains CSNAV-1, CMCV-1 and COPV-2 is contaminant-dependent. We showed differences even between two variants of Chattonella (Chattonella marina var. marina and C. marina var. ovata). Furthermore, we were able to show the different mode of action of two common pollutants by simple cytotoxic parameters like total protein and chlorophyll a content as well as by cell counting analysis. PMID:26417254

Analysis of concentration-dependent effects of copper and PCB on different Chattonella spp. microalgae (raphidophyceae) cultivated in artificial seawater medium.

PubMed

Niestroy, Jeanette; Martínez, Alfonso Bárbara; Band-Schmidt, Christine J

2014-01-01

In the present study, the effect on the chlorophyll a and the total protein content as well as the Chattonella spp. cell viability were examined after concentration-dependent exposure to CuCl2 and Aroclor 1242. The comparison between various raphidophyte strains provides an insight into the different susceptibilities to contaminants of Chattonella subsalsa (CSNAV-1), C. marina var. marina (CMCV-1) and C. marina var. ovata (COPV-2). The microalgae were cultivated in artificial seawater medium. Exponentially growing microalgae (8-10 days in culture) were used for exposure experiments. We observed in all three raphidophyte species cytotoxicity-mediated modifications beginning at concentrations of 150 and 200 µM of the heavy metal copper after 24 hours exposure. But interestingly, the three strains exhibited only slight differences in their susceptibility to CuCl2. C. subsalsa and C. marina var. marina cells were first affected at the chlorophyll a level and in cell viability. The total protein amount was reduced significantly only after exposure to 300 µM of CuCl2. However, C. marina var. ovata microalgae showed similar reduction curves for all three analysed cytotoxicity endpoints after heavy metal exposure. On the other hand, after Aroclor 1242 incubation the cytotoxic modification pattern indicated clearly the different susceptibilities of the three raphidophyte strains. C. subsalsa cells noticeably exhibited a decrease in the analysed pigment amount (30-20 % compared to that of the control) already after 0.007 mg/L PCB exposure. In contrast, cell viability and total protein content were slightly reduced and fell below the 50 % threshold after 0.7 and 3.3 mg/L of Aroclor 1242, respectively. Interestingly, C. marina var. ovata showed almost no cytotoxic modification caused by the PCB mixture. Only the concentration of 0.7 mg/L Aroclor 1242 clearly affected the cell viability. As opposed to that we observed a concentration-dependent decrease of cell viability and chlorophyll a amount in CMCV-1 microalgae. These observations confirmed that the susceptibility of the raphidophytes strains CSNAV-1, CMCV-1 and COPV-2 is contaminant-dependent. We showed differences even between two variants of Chattonella (Chattonella marina var. marina and C. marina var. ovata). Furthermore, we were able to show the different mode of action of two common pollutants by simple cytotoxic parameters like total protein and chlorophyll a content as well as by cell counting analysis.

Structural CNT Composites. Part I; Developing a Carbon Nanotube Filament Winder

NASA Technical Reports Server (NTRS)

Sauti, Godfrey; Kim, Jae-Woo; Wincheski, Russell A.; Antczak, Andrew; Campero, Jamie C.; Luong, Hoa H.; Shanahan, Michelle H.; Stelter, Christopher J.; Siochi, Emilie J.

2015-01-01

Carbon nanotube (CNT) based materials promise advances in the production of high strength and multifunctional components for aerospace and other applications. Specifically, in tension dominated applications, the latest CNT based filaments are yielding composite properties comparable to or exceeding composites from more established fibers such as Kevlar and carbon fiber. However, for the properties of these materials to be fully realized at the component level, suitable manufacturing processes have to be developed. These materials handle differently from conventional fibers, with different wetting characteristics and behavior under load. The limited availability of bulk forms also requires that the equipment be scaled down accordingly to tailor the process development approach to material availability. Here, the development of hardware and software for filament winding of carbon nanotube based tapes and yarns is described. This hardware features precision guidance of the CNT material and control of the winding tension over a wide range in an open architecture that allows for effective process control and troubleshooting during winding. Use of the filament winder to develop CNT based Composite Overwrapped Pressure Vessels (COPVs) shall also be discussed.

Use of Statistical Analysis of Acoustic Emission Data on Carbon-Epoxy COPV Materials-of-Construction for Enhanced Felicity Ratio Onset Determination

NASA Technical Reports Server (NTRS)

Abraham, Arick Reed A.; Johnson, Kenneth L.; Nichols, Charles T.; Saulsberry, Regor L.; Waller, Jess M.

2012-01-01

Broadband modal acoustic emission (AE) data were acquired during intermittent load hold tensile test profiles on Toray T1000G carbon fiber-reinforced epoxy (C/Ep) single tow specimens. A novel trend seeking statistical method to determine the onset of significant AE was developed, resulting in more linear decreases in the Felicity ratio (FR) with load, potentially leading to more accurate failure prediction. The method developed uses an exponentially weighted moving average (EWMA) control chart. Comparison of the EWMA with previously used FR onset methods, namely the discrete (n), mean (n (raised bar)), normalized (n%) and normalized mean (n(raised bar)%) methods, revealed the EWMA method yields more consistently linear FR versus load relationships between specimens. Other findings include a correlation between AE data richness and FR linearity based on the FR methods discussed in this paper, and evidence of premature failure at lower than expected loads. Application of the EWMA method should be extended to other composite materials and, eventually, composite components such as composite overwrapped pressure vessels. Furthermore, future experiments should attempt to uncover the factors responsible for infant mortality in C/Ep strands.

Stress Rupture Life Reliability Measures for Composite Overwrapped Pressure Vessels

NASA Technical Reports Server (NTRS)

Murthy, Pappu L. N.; Thesken, John C.; Phoenix, S. Leigh; Grimes-Ledesma, Lorie

2007-01-01

Composite Overwrapped Pressure Vessels (COPVs) are often used for storing pressurant gases onboard spacecraft. Kevlar (DuPont), glass, carbon and other more recent fibers have all been used as overwraps. Due to the fact that overwraps are subjected to sustained loads for an extended period during a mission, stress rupture failure is a major concern. It is therefore important to ascertain the reliability of these vessels by analysis, since the testing of each flight design cannot be completed on a practical time scale. The present paper examines specifically a Weibull statistics based stress rupture model and considers the various uncertainties associated with the model parameters. The paper also examines several reliability estimate measures that would be of use for the purpose of recertification and for qualifying flight worthiness of these vessels. Specifically, deterministic values for a point estimate, mean estimate and 90/95 percent confidence estimates of the reliability are all examined for a typical flight quality vessel under constant stress. The mean and the 90/95 percent confidence estimates are computed using Monte-Carlo simulation techniques by assuming distribution statistics of model parameters based also on simulation and on the available data, especially the sample sizes represented in the data. The data for the stress rupture model are obtained from the Lawrence Livermore National Laboratories (LLNL) stress rupture testing program, carried out for the past 35 years. Deterministic as well as probabilistic sensitivities are examined.

Analysis of Impact Induced Damage and its Effect on Structural Integrity of Space Flight Composite Overwrapped Pressure Vessels

NASA Technical Reports Server (NTRS)

Wnuk, Michael P.

1997-01-01

The objective of this research work has been to provide analytical background and support to the ongoing experimental program at NASA, White Sands Test Facility, involving testing composite overwrapped pressure vessels (COPV) for impact damage and cyclic pressurization. Preliminary theoretical basis, including the governing equations for a shallow shell subjected to internal pressure, has been established. Effects of the Griffith type cracks on the structural integrity of the cylindrical vessel were evaluated by methods of Fracture Mechanics. The results indicate that the effective mass of the pressure vessel is an important factor influencing the response to impact events. We also have found that the material properties of the target, contained in the constitutive equations of the composite attached to the Aluminum liner, dominate the impact event in the low velocity range, the material properties become less important, while the target mass distribution and the impactor mass become more significant as the velocity of the impactor increases. Therefore, at high-velocity impact it is not only the kinetic energy of the impactor but also its mass which has a significant effect on the dynamics of the event, and consequently on the induced damage. This work also suggests a methodology for an assessment of the rate of loading effects on the degradation of the material toughness associated with a high-velocity impact where the rate effects become significant. To model the rate dependence of the material response a viscoelastic-plastic constitutive equations were assumed, and on this basis predictions are made regarding the rate dependent material resistance curve. Other dynamic phenomena associated with the impact event have been treated in the framework of the Computational Mechanics using the courtesy of Prof. P. Guebelle and his graduate student at University of Illinois at Urbana-Champaign who have an access to a super-fast computer located on their campus. Finally, the guidelines for a follow-up research program are provided in the body of this report. They address three major areas: theoretical research, numerical studies, and further experimental work.

Novel papillomavirus isolated from the oral mucosa of a polar bear does not cluster with other papillomaviruses of carnivores.

PubMed

Stevens, Hans; Rector, Annabel; Bertelsen, Mads F; Leifsson, Pall S; Van Ranst, Marc

2008-05-25

Papillomatosis has been documented in several carnivores, and papillomavirus (PV) types have been characterized from lesions in a number of carnivore species: the canine oral PV (COPV), the Felis domesticus PV type 1 (FdPV-1) isolated from a Persian cat, the Procyon lotor PV type 1 (PlPV-1) isolated from a raccoon, the canine PV type 2 (CPV-2) from a dog's foot pad lesion and the canine PV type 3 (CPV-3) associated with a canine epidermodysplasia verruciformis - like disease. A tissue sample was taken from a papillomatous lesion on the oral mucosa of a polar bear (Ursus maritimus). Extracted DNA was used as a template for multiply primed rolling-circle amplification (RCA), and restriction enzyme analysis of the RCA product indicated the presence of papillomaviral DNA. The genome of this PV was cloned and the complete genomic sequence was determined. The Ursus maritimus PV type 1 (UmPV-1) genome counts 7582 basepairs and is smaller than that of other papillomaviruses from carnivore species. UmPV-1 contains the typical noncoding region NCR1, but unlike the carnivore PVs of the Lambda genus, UmPV-1 does not possess a second noncoding region NCR2. Phylogenetic analysis based on a nucleotide sequence alignment of the L1 ORF of UmPV-1 and 51 other PV types indicates that UmPV-1 does not cluster with any of the other carnivore PVs, but branches off near the root of the common branch of the genus Alphapapillomavirus.

Some Observations on Damage Tolerance Analyses in Pressure Vessels

NASA Technical Reports Server (NTRS)

Raju, Ivatury S.; Dawicke, David S.; Hampton, Roy W.

2017-01-01

AIAA standards S080 and S081 are applicable for certification of metallic pressure vessels (PV) and composite overwrap pressure vessels (COPV), respectively. These standards require damage tolerance analyses with a minimum reliable detectible flaw/crack and demonstration of safe life four times the service life with these cracks at the worst-case location in the PVs and oriented perpendicular to the maximum principal tensile stress. The standards require consideration of semi-elliptical surface cracks in the range of aspect ratios (crack depth a to half of the surface length c, i.e., (a/c) of 0.2 to 1). NASA-STD-5009 provides the minimum reliably detectible standard crack sizes (90/95 probability of detection (POD) for several non-destructive evaluation (NDE) methods (eddy current (ET), penetrant (PT), radiography (RT) and ultrasonic (UT)) for the two limits of the aspect ratio range required by the AIAA standards. This paper tries to answer the questions: can the safe life analysis consider only the life for the crack sizes at the two required limits, or endpoints, of the (a/c) range for the NDE method used or does the analysis need to consider values within that range? What would be an appropriate method to interpolate 90/95 POD crack sizes at intermediate (a/c) values? Several procedures to develop combinations of a and c within the specified range are explored. A simple linear relationship between a and c is chosen to compare the effects of seven different approaches to determine combinations of aj and cj that are between the (a/c) endpoints. Two of the seven are selected for evaluation: Approach I, the simple linear relationship, and a more conservative option, Approach III. For each of these two Approaches, the lives are computed for initial semi-elliptic crack configurations in a plate subjected to remote tensile fatigue loading with an R-ratio of 0.1, for an assumed material evaluated using NASGRO (registered 4) version 8.1. These calculations demonstrate that for this loading, using Approach I and the initial detectable crack sizes at the (a/c) endpoints in 5009 specified for the ET and UT NDE methods, the smallest life is not at the two required limits of the (a/c) range, but rather is at an intermediate configuration in the range (a/c) of 0.4 to 0.6. Similar analyses using both Approach I and III with the initial detectable crack size at the (a/c) endpoints in 5009 for PT NDE showed the smallest life may be at an (a/c) endpoint or an intermediate (a/c), depending upon which Approach is used. As such, analyses that interrogate only the two (a/c) values of 0.2 and 1 may result in unconservative life predictions. The standard practice may need to be revised based on these results.

Composite Overwrap Pressure Vessels: Mechanics and Stress Rupture Lifting Philosophy

NASA Technical Reports Server (NTRS)

Thesken, John C.; Murthy, Pappu L. N.; Phoenix, S. L.

2009-01-01

The NASA Engineering and Safety Center (NESC) has been conducting an independent technical assessment to address safety concerns related to the known stress rupture failure mode of filament wound pressure vessels in use on Shuttle and the International Space Station. The Shuttle s Kevlar-49 (DuPont) fiber overwrapped tanks are of particular concern due to their long usage and the poorly understood stress rupture process in Kevlar-49 filaments. Existing long term data show that the rupture process is a function of stress, temperature and time. However due to the presence of load sharing liners and the complex manufacturing procedures, the state of actual fiber stress in flight hardware and test articles is not clearly known. Indeed nonconservative life predictions have been made where stress rupture data and lifing procedures have ignored the contribution of the liner in favor of applied pressure as the controlling load parameter. With the aid of analytical and finite element results, this paper examines the fundamental mechanical response of composite overwrapped pressure vessels including the influence of elastic plastic liners and degraded/creeping overwrap properties. Graphical methods are presented describing the non-linear relationship of applied pressure to Kevlar-49 fiber stress/strain during manufacturing, operations and burst loadings. These are applied to experimental measurements made on a variety of vessel systems to demonstrate the correct calibration of fiber stress as a function of pressure. Applying this analysis to the actual qualification burst data for Shuttle flight hardware revealed that the nominal fiber stress at burst was in some cases 23 percent lower than what had previously been used to predict stress rupture life. These results motivate a detailed discussion of the appropriate stress rupture lifing philosophy for COPVs including the correct transference of stress rupture life data between dissimilar vessels and test articles.

Composite Overwrap Pressure Vessels: Mechanics and Stress Rupture Lifing Philosophy

NASA Technical Reports Server (NTRS)

Thesken, John C.; Murthy, Pappu L. N.; Phoenix, Leigh

2007-01-01

The NASA Engineering and Safety Center (NESC) has been conducting an independent technical assessment to address safety concerns related to the known stress rupture failure mode of filament wound pressure vessels in use on Shuttle and the International Space Station. The Shuttle's Kevlar-49 fiber overwrapped tanks are of particular concern due to their long usage and the poorly understood stress rupture process in Kevlar-49 filaments. Existing long term data show that the rupture process is a function of stress, temperature and time. However due to the presence of load sharing liners and the complex manufacturing procedures, the state of actual fiber stress in flight hardware and test articles is not clearly known. Indeed non-conservative life predictions have been made where stress rupture data and lifing procedures have ignored the contribution of the liner in favor of applied pressure as the controlling load parameter. With the aid of analytical and finite element results, this paper examines the fundamental mechanical response of composite overwrapped pressure vessels including the influence of elastic-plastic liners and degraded/creeping overwrap properties. Graphical methods are presented describing the non-linear relationship of applied pressure to Kevlar-49 fiber stress/strain during manufacturing, operations and burst loadings. These are applied to experimental measurements made on a variety of vessel systems to demonstrate the correct calibration of fiber stress as a function of pressure. Applying this analysis to the actual qualification burst data for Shuttle flight hardware revealed that the nominal fiber stress at burst was in some cases 23% lower than what had previously been used to predict stress rupture life. These results motivate a detailed discussion of the appropriate stress rupture lifing philosophy for COPVs including the correct transference of stress rupture life data between dissimilar vessels and test articles.

An evaluation of third molar eruption for assessment of chronologic age: A panoramic study

PubMed Central

Tuteja, Monica; Bahirwani, Shraddha; Balaji, P

2012-01-01

Objectives: The identity of a person can be established by assessing one's age, and in order to be entitled to civil rights and social benefits, verification of the chronological age is required and thereby age estimation has gained an increasing significance in recent years. Tooth eruption is one of the criteria of developmental morphology that can be evaluated by either clinical examination or by evaluation of dental radiographs to determine the dental age. The present study was aimed to evaluate the reliability of the third molar eruption stage as a parameter for forensic age estimation in living subjects. Materials and Methods: The stage of wisdom tooth eruption in 77 male and 73 female Indian subjects aged between 12–26 years was determined by subjecting them to conventional orthopantomograms and was interpreted to assess the third molar eruption stages to evaluate the dental age. Results: Predicted minimum age and mean age of the study sample were found to be significant predictors (P<0.001) of actual age. Minimum age was able to explain 58.3% of the variation in actual age and the mean age was able to explain 60.3% of variation in actual age. Conclusion: Third molar is fairly a reliable indicator to determine the age of alveolar, gingival, and complete emergence of third molar in the occlusal plane in adolescents and young adults. Minimum and most probable ages of examined subjects can also be evaluated using third molar eruption stage. PMID:23087576

An evaluation of third molar eruption for assessment of chronologic age: A panoramic study.

PubMed

Tuteja, Monica; Bahirwani, Shraddha; Balaji, P

2012-01-01

The identity of a person can be established by assessing one's age, and in order to be entitled to civil rights and social benefits, verification of the chronological age is required and thereby age estimation has gained an increasing significance in recent years. Tooth eruption is one of the criteria of developmental morphology that can be evaluated by either clinical examination or by evaluation of dental radiographs to determine the dental age. The present study was aimed to evaluate the reliability of the third molar eruption stage as a parameter for forensic age estimation in living subjects. The stage of wisdom tooth eruption in 77 male and 73 female Indian subjects aged between 12-26 years was determined by subjecting them to conventional orthopantomograms and was interpreted to assess the third molar eruption stages to evaluate the dental age. Predicted minimum age and mean age of the study sample were found to be significant predictors (P<0.001) of actual age. Minimum age was able to explain 58.3% of the variation in actual age and the mean age was able to explain 60.3% of variation in actual age. Third molar is fairly a reliable indicator to determine the age of alveolar, gingival, and complete emergence of third molar in the occlusal plane in adolescents and young adults. Minimum and most probable ages of examined subjects can also be evaluated using third molar eruption stage.

20 CFR 416.924b - Age as a factor of evaluation in the sequential evaluation process for children.

Code of Federal Regulations, 2011 CFR

2011-04-01

... infants. We generally use chronological age (that is, a child's age based on birth date) when we decide... chronological age. When we evaluate the development or linear growth of a child born prematurely, we may use a... sequential evaluation process for children. 416.924b Section 416.924b Employees' Benefits SOCIAL SECURITY...

20 CFR 416.924b - Age as a factor of evaluation in the sequential evaluation process for children.

Code of Federal Regulations, 2013 CFR

2013-04-01

... infants. We generally use chronological age (that is, a child's age based on birth date) when we decide... chronological age. When we evaluate the development or linear growth of a child born prematurely, we may use a... sequential evaluation process for children. 416.924b Section 416.924b Employees' Benefits SOCIAL SECURITY...

20 CFR 416.924b - Age as a factor of evaluation in the sequential evaluation process for children.

Code of Federal Regulations, 2010 CFR

2010-04-01

... infants. We generally use chronological age (that is, a child's age based on birth date) when we decide... chronological age. When we evaluate the development or linear growth of a child born prematurely, we may use a... sequential evaluation process for children. 416.924b Section 416.924b Employees' Benefits SOCIAL SECURITY...

20 CFR 416.924b - Age as a factor of evaluation in the sequential evaluation process for children.

Code of Federal Regulations, 2014 CFR

2014-04-01

... infants. We generally use chronological age (that is, a child's age based on birth date) when we decide... chronological age. When we evaluate the development or linear growth of a child born prematurely, we may use a... sequential evaluation process for children. 416.924b Section 416.924b Employees' Benefits SOCIAL SECURITY...

20 CFR 416.924b - Age as a factor of evaluation in the sequential evaluation process for children.

Code of Federal Regulations, 2012 CFR

2012-04-01

... infants. We generally use chronological age (that is, a child's age based on birth date) when we decide... chronological age. When we evaluate the development or linear growth of a child born prematurely, we may use a... sequential evaluation process for children. 416.924b Section 416.924b Employees' Benefits SOCIAL SECURITY...

Age Differences in Voice Evaluation: From Auditory-Perceptual Evaluation to Social Interactions

ERIC Educational Resources Information Center

Lortie, Catherine L.; Deschamps, Isabelle; Guitton, Matthieu J.; Tremblay, Pascale

2018-01-01

Purpose: The factors that influence the evaluation of voice in adulthood, as well as the consequences of such evaluation on social interactions, are not well understood. Here, we examined the effect of listeners' age and the effect of talker age, sex, and smoking status on the auditory-perceptual evaluation of voice, voice-related psychosocial…

Age-Related Changes to the Neural Correlates of Social Evaluation

PubMed Central

Cassidy, Brittany S.; Shih, Joanne Y.; Gutchess, Angela H.

2012-01-01

Recent work suggests the existence of a specialized neural system underlying social processing that may be relatively spared with age, unlike pervasive aging-related decline occurring in many cognitive domains. We investigated how neural mechanisms underlying social evaluation are engaged with age, and how age-related changes to socioemotional goals affect recruitment of regions within this network. In a functional MRI study, fifteen young and fifteen older adults formed behavior-based impressions of individuals. They also responded to a prompt that was interpersonally meaningful, social but interpersonally irrelevant, or non-social. Both age groups engaged regions implicated in mentalizing and impression formation when making social relative to non-social evaluations, including dorsal and ventral medial prefrontal cortices, precuneus, and temporoparietal junction. Older adults had increased activation over young in right temporal pole when making social relative to non-social evaluations, suggesting reliance on past experiences when evaluating others. Young had greater activation than old in posterior cingulate gyrus when making interpersonally irrelevant, compared to interpersonally meaningful, evaluations, potentially reflecting enhanced valuation of this information. The findings demonstrate the age-related preservation of the neural correlates underlying social evaluation, and suggest that functioning in these regions might be mediated by age-related changes in socioemotional goals. PMID:22439896

A Retrospective Investigation on Canine Papillomavirus 1 (CPV1) in Oral Oncogenesis Reveals Dogs Are Not a Suitable Animal Model for High-Risk HPV-Induced Oral Cancer

PubMed Central

Porcellato, Ilaria; Brachelente, Chiara; Guelfi, Gabriella; Reginato, Alice; Sforna, Monica; Bongiovanni, Laura; Mechelli, Luca

2014-01-01

CPV1 (also called COPV) is a papillomavirus responsible for oral papillomatosis in young dogs. The involvement of this viral type in oral oncogenesis has been hypothesized in oral squamous cell carcinomas (SCCs), but has never been investigated in other neoplastic and hyperplastic oral lesions of dogs. Aim of this study was to investigate the presence of CPV1 in different neoplastic and hyperplastic lesions in order to assess its role in canine oral oncogenesis; according to the results obtained, a second aim of the study was to define if the dog can be considered a valid animal model for oral high risk HPV-induced tumors. Eighty-eight formalin-fixed, paraffin-embedded (FFPE) canine oral lesions including 78 oral tumors (papillomas, SCCs, melanomas, ameloblastomas, oral adenocarcinomas) and 10 hyperplastic lesions (gingival hyperplasia) were investigated with immunohistochemistry for the presence of papillomavirus L1 protein and with Real-Time PCR for CPV1 DNA. RT-PCR for RNA was performed on selected samples. All viral papillomas tested were positive for immunohistochemistry and Real-time PCR. In 3/33 (10%) SCCs, viral DNA was demonstrated but no viral RNA could be found. No positivity was observed both with immunohistochemistry and Real-Time PCR in the other hyperplastic and neoplastic lesions of the oral cavity of dogs. Even though the finding of CPV1 DNA in few SCCs in face of a negative immunohistochemistry could support the hypothesis of an abortive infection in the development of these lesions, the absence of viral RNA points out that CPV1 more likely represents an innocent bystander in SCC oncogenesis. The study demonstrates a strong association between CPV1 and oral viral papillomas whereas viral contribution to the pathogenesis of other oral lesions seems unlikely. Moreover, it suggests that a canine model of CPV1 infection for HPV-induced oncogenesis could be inappropriate. PMID:25401953

Job Characteristics, Core Self-Evaluations, and Job Satisfaction: What's Age Got to Do with It?

ERIC Educational Resources Information Center

Besen, Elyssa; Matz-Costa, Christina; Brown, Melissa; Smyer, Michael A.; Pitt-Catsouphes, Martha

2013-01-01

There is a well-established relationship between age and job satisfaction. To date, there is little research about how many well-known predictors of job satisfaction, specifically job characteristics and core self-evaluations, may vary with age. Using a multi-worksite sample of 1,873 employed adults aged 17 to 81, this study evaluated the extent…

Nutritional risk and anthropometric evaluation in pediatric liver transplantation.

PubMed

Zamberlan, Patrícia; Leone, Cláudio; Tannuri, Uenis; Carvalho, Werther Brunow de; Delgado, Artur Figueiredo

2012-12-01

To analyze the nutritional status of pediatric patients after orthotopic liver transplantation and the relationship with short-term clinical outcome. Anthropometric evaluations of 60 children and adolescents after orthotopic liver transplantation, during the first 24 hours in a tertiary pediatric intensive care unit. Nutritional status was determined from the Z score for the following indices: weight/age height/age or length/age, weight/height or weight/length, body mass index/age, arm circumference/age and triceps skinfold/age. The severity of liver disease was evaluated using one of the two models which was adequated to the patients' age: 1. Pediatric End-stage Liver Disease, 2. Model for End-Stage Liver Disease. We found 50.0% undernutrition by height/age; 27.3% by weight/age; 11.1% by weight/height or weight/ length; 10.0% by body mass index/age; 61.6% by arm circumference/age and 51.0% by triceps skinfold/age. There was no correlation between nutritional status and Pediatric End-stage Liver Disease or mortality. We found a negative correlation between arm circumference/age and length of hospitalization. Children with chronic liver diseases experience a significant degree of undernutrition, which makes nutritional support an important aspect of therapy. Despite the difficulties in assessment, anthropometric evaluation of the upper limbs is useful to evaluate nutritional status of children before or after liver transplantation.

The rules of implicit evaluation by race, religion, and age.

PubMed

Axt, Jordan R; Ebersole, Charles R; Nosek, Brian A

2014-09-01

The social world is stratified. Social hierarchies are known but often disavowed as anachronisms or unjust. Nonetheless, hierarchies may persist in social memory. In three studies (total N > 200,000), we found evidence of social hierarchies in implicit evaluation by race, religion, and age. Participants implicitly evaluated their own racial group most positively and the remaining racial groups in accordance with the following hierarchy: Whites > Asians > Blacks > Hispanics. Similarly, participants implicitly evaluated their own religion most positively and the remaining religions in accordance with the following hierarchy: Christianity > Judaism > Hinduism or Buddhism > Islam. In a final study, participants of all ages implicitly evaluated age groups following this rule: children > young adults > middle-age adults > older adults. These results suggest that the rules of social evaluation are pervasively embedded in culture and mind. © The Author(s) 2014.

Validity of a figure rating scale assessing body size perception in school-age children.

PubMed

Lombardo, Caterina; Battagliese, Gemma; Pezzuti, Lina; Lucidi, Fabio

2014-01-01

This study aimed to provide data concerning the validity of a short sequence of face valid pictorial stimuli assessing the perception of body size in school-age children. A sequence of gender and age-appropriate silhouettes was administered to 314 boys and girls aged 6-14 years. The self-evaluations provided by the children correlated significantly with their actual BMI corrected for age. Furthermore, the children's self-evaluations always significantly correlated with the evaluations provided by the three external observers; i.e., both parents and the interviewers. The results indicate that this sequence of pictorial stimuli, depicting realistic human forms appropriate for children, is a valid measure of children's body image. Relevant differences across age groups were also found, indicating that before the age of eight, the correlations between the children's self-evaluations and their BMI or the judgments of the three observers are lower than in the other age groups.

Human factors evaluation of the work environment of operators engaged in the inspection and repair of aging aircraft.

DOT National Transportation Integrated Search

1992-01-01

Site evaluations of air carriers and repair stations conducting inspections and heavy maintenance on PART 121 aging aircraft were conducted during 1989-90 under the FAA's Office of Flight Standards Aging Fleet Evaluation Program. This report presents...

Greater Perceived Similarity between Self and Own-Age Others in Older than Young Adults

PubMed Central

Lin, Tian; Ankudowich, Elizabeth; Ebner, Natalie C.

2017-01-01

As people age, they increasingly incorporate age-stereotypes into their self-view. Based on this evidence we propose that older compared to young adults identify to a greater extent with their own-age group on personality traits, an effect that may be particularly pronounced for positive traits. Two studies tested these hypotheses by examining associations in young and older adults between evaluations of self and own-age others on personality traits that varied on valence. In both studies, young and older participants rated personality trait adjectives on age typicality, valence, and self typicality. Converging results across both studies showed that older compared to young participants were more likely to endorse personality traits as self-typical when those traits were also perceived as more typical for their own-age group, independent of whether age was made salient to participants prior to evaluation. In addition, there was evidence that the association between evaluations of self and own-age others in older participants was greater for more positive personality traits. This age-differential pattern is discussed in the context of increased age salience in aging and its effect on the similarity between evaluations of self and own-age others in older compared to young adults. PMID:28471216

Evaluation and clinical significance of the stomach age model for evaluating aging of the stomach-a multicenter study in China

PubMed Central

2014-01-01

Background A higher prevalence of chronic atrophic gastritis (CAG) occurs in younger adults in Asia. We used Stomach Age to examine the different mechanisms of CAG between younger adults and elderly individuals, and established a simple model of cancer risk that can be applied to CAG surveillance. Methods Stomach Age was determined by FISH examination of telomere length in stomach biopsies. Δψm was also determined by flow cytometry. Sixty volunteers were used to confirm the linear relationship between telomere length and age while 120 subjects were used to build a mathematical model by a multivariate analysis. Overall, 146 subjects were used to evaluate the validity of the model, and 1,007 subjects were used to evaluate the relationship between prognosis and Δage (calculated from the mathematical model). ROC curves were used to evaluate the relationship between prognosis and Δage and to determine the cut-off point for Δage. Results We established that a tight linear relationship between the telomere length and the age. The telomere length was obvious different between patients with and without CAG even in the same age. Δψm decreased in individuals whose Stomach Age was greater than real age, especially in younger adults. A mathematical model of Stomach Age (real age + Δage) was successfully constructed which was easy to apply in clinical work. A higher Δage was correlated with a worse outcome. The criterion of Δage >3.11 should be considered as the cut-off to select the subgroup of patients who require endoscopic surveillance. Conclusion Variation in Stomach Age between individuals of the same biological age was confirmed. Attention should be paid to those with a greater Stomach Age, especially in younger adults. The Δage in the Simple Model can be used as a criterion to select CAG patients for gastric cancer surveillance. PMID:25057261

Age-Related Differences in Evaluating Developmental Stability

ERIC Educational Resources Information Center

Mustafic, Maida; Freund, Alexandra M.

2013-01-01

Two studies examined the hypothesis that the evaluation of developmental stability changes across adulthood. Results of Study 1 ("N" = 119) supported the expectation that older adults ("M"[subscript age] = 65.29 years)--compared to younger ("M"[subscript age] = 23.38 years) and middle-aged adults…

[Study on objectively evaluating skin aging according to areas of skin texture].

PubMed

Shan, Gaixin; Gan, Ping; He, Ling; Sun, Lu; Li, Qiannan; Jiang, Zheng; He, Xiangqian

2015-02-01

Skin aging principles play important roles in skin disease diagnosis, the evaluation of skin cosmetic effect, forensic identification and age identification in sports competition, etc. This paper proposes a new method to evaluate the skin aging objectively and quantitatively by skin texture area. Firstly, the enlarged skin image was acquired. Then, the skin texture image was segmented by using the iterative threshold method, and the skin ridge image was extracted according to the watershed algorithm. Finally, the skin ridge areas of the skin texture were extracted. The experiment data showed that the average areas of skin ridges, of both men and women, had a good correlation with age (the correlation coefficient r of male was 0.938, and the correlation coefficient r of female was 0.922), and skin texture area and age regression curve showed that the skin texture area increased with age. Therefore, it is effective to evaluate skin aging objectively by the new method presented in this paper.

Dissecting the Voice: Health Professions Students' Perceptions of Instructor Age and Gender in an Online Environment and the Impact on Evaluations for Faculty

ERIC Educational Resources Information Center

Doubleday, Alison F.; Lee, Lisa M. J.

2016-01-01

Gender and age bias is well-documented in academia with many studies demonstrating bias in students' evaluations of instructors. Failure of an instructor to meet gender or age-based expectations can translate to lower scores or negative comments on evaluations. While there is some evidence of bias in students' evaluations of online instructors,…

Aging in Community Nutrition, Diet Therapy, and Nutrition and Aging Textbooks

ERIC Educational Resources Information Center

O'Neill, Peggy Schafer; Wellman, Nancy S.; Himburg, Susan P.; Johnson, Paulette; Elfenbein, Pamela

2005-01-01

Using content analysis, this study evaluated the aging content and context in 11 nutrition sub-specialty textbooks: community nutrition (n = 3), diet therapy (n = 4), and nutrition and aging (n = 4). Pages with paragraphs on aging were identified in community nutrition and diet therapy textbooks, and 10% random samples of pages were evaluated in…

Multiple standards of aging: gender-specific age stereotypes in different life domains.

PubMed

Kornadt, Anna E; Voss, Peggy; Rothermund, Klaus

2013-12-01

Whereas it is often stated that aging might have more negative consequences for the evaluation of women compared to men, evidence for this assumption is mixed. We took a differentiated look at age stereotypes of men and women, assuming that the life domain in which older persons are rated moderates gender differences in age stereotypes. A sample of 298 participants aged 20-92 rated 65 - year-old men and women on evaluative statements in eight different life domains. Furthermore, perceptions of gender- and domain-specific age-related changes were assessed by comparing the older targets to 45 - year-old men and women, respectively. The results speak in favor of the domain specificity of evaluative asymmetries in age stereotypes for men and women, and imply that an understanding of gendered perceptions of aging requires taking into account the complexities of domain-specific views on aging.

[Evaluation of olfaction in healthy subjects using the Sniffing Sticks battery].

PubMed

Hudson, Lorena; Silva, M Consuelo; Núñez, Juan Cristóbal; Gómez, Rodrigo; Venegas-Francke, Pablo

2012-04-01

Olfaction dysfunction is linked to neurodegenerative diseases, therefore the evaluation of this function is becoming important To evaluate olfaction in healthy participants. We evaluated 44 healthy males and 55 females, aged 21 to 89 years with the Sniffing Sticks battery to determine normal values in Chilean population. During the test, participants must correctly identify 12 different odors. Normal olfaction, hyposmia and anosmia were defined. An age related decline in olfaction was observed, especially among males aged 59 years or more. This study provides age and gender specific normal values for the Sniffing Sticks battery.

An evaluation of life satisfaction and health - Quality of life of senior citizens.

PubMed

Ziółkowski, Artur; Błachnio, Aleksandra; Pąchalska, Maria

2015-01-01

Modern medicine is still searching for the antecedents which will lead to successful aging. The article discusses the self-perception of life satisfaction and health of senior citizens. The aim of the study was to determine the relationship between self-evaluation of life satisfaction and health by senior citizens in comparison to different age groups. The study included 463 persons - 230 men and 233 women. The age of the participants was in the range 16 - 83 years. All participants were asked to fill the Life Satisfaction Questionnaire (Fragebogen zur Lebenszufriedenheit - FLZ). The FLZ questionnaire assesses the global life satisfaction of a person and health domain separately. The results show age-related differences in the evaluation of life satisfaction. Accordingly, there is a significant change in health evaluations in different age groups, but there are no significant gender differences in health self-report data. The senior citizens' assessment of general health, although the lowest among all the age-subgroups, showed significant difference only in relation to the people below 45 years of age. The significant differences in satisfaction from mental health occurred only for the elderly and participants aged 25-34 and 35-44. Life satisfaction is associated with subjective health evaluations. There are two domains (mental health and performance) that are positively evaluated by more than two-thirds of senior citizens. The observed differences challenge stereotypes and prejudices relating to negative aging process. Senior citizens can improve their control beliefs and develop self-regulation and coping skills.

The use of information theory for the evaluation of biomarkers of aging and physiological age.

PubMed

Blokh, David; Stambler, Ilia

2017-04-01

The present work explores the application of information theoretical measures, such as entropy and normalized mutual information, for research of biomarkers of aging. The use of information theory affords unique methodological advantages for the study of aging processes, as it allows evaluating non-linear relations between biological parameters, providing the precise quantitative strength of those relations, both for individual and multiple parameters, showing cumulative or synergistic effect. Here we illustrate those capabilities utilizing a dataset on heart disease, including diagnostic parameters routinely available to physicians. The use of information-theoretical methods, utilizing normalized mutual information, revealed the exact amount of information that various diagnostic parameters or their combinations contained about the persons' age. Based on those exact informative values for the correlation of measured parameters with age, we constructed a diagnostic rule (a decision tree) to evaluate physiological age, as compared to chronological age. The present data illustrated that younger subjects suffering from heart disease showed characteristics of people of higher age (higher physiological age). Utilizing information-theoretical measures, with additional data, it may be possible to create further clinically applicable information-theory-based markers and models for the evaluation of physiological age, its relation to age-related diseases and its potential modifications by therapeutic interventions. Copyright © 2017 Elsevier B.V. All rights reserved.

[Development and prospect on skeletal age evaluation methods of X-ray film].

PubMed

Wang, Ya-hui; Zhu, Guang-you; Qiao, Ke; Bian, Shi-zhong; Fan, Li-hua; Cheng, Yi-bin; Ying, Chong-liang; Shen, Yan

2007-10-01

The traditional methods of skeletal age estimation mainly include Numeration, Atlas, and Counting scores. In recent years, other new methods were proposed by several scholars. Utilizing image logical characteristics of X-ray film to extrapolate skeletal age is a key means by present forensic medicine workers in evaluating skeletal age. However, there exist some variations when we present the conclusion of skeletal age as an "evidence" directly to the Justice Trial Authority. In order to enhance the accuracy of skeletal age determination, further investigation for appropriate methodology should be undertaken. After a collective study of pertinent domestic and international literatures, we present this review of the research and advancement on skeletal age evaluation methods of X-ray film.

20 CFR 408.413 - How do we evaluate the evidence of age you give us?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false How do we evaluate the evidence of age you give us? 408.413 Section 408.413 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Age § 408.413 How do we evaluate the evidence...

20 CFR 408.413 - How do we evaluate the evidence of age you give us?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false How do we evaluate the evidence of age you give us? 408.413 Section 408.413 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Age § 408.413 How do we evaluate the evidence...

20 CFR 408.413 - How do we evaluate the evidence of age you give us?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false How do we evaluate the evidence of age you give us? 408.413 Section 408.413 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Age § 408.413 How do we evaluate the evidence...

20 CFR 408.413 - How do we evaluate the evidence of age you give us?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false How do we evaluate the evidence of age you give us? 408.413 Section 408.413 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Age § 408.413 How do we evaluate the evidence...

20 CFR 408.413 - How do we evaluate the evidence of age you give us?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false How do we evaluate the evidence of age you give us? 408.413 Section 408.413 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Evidence Requirements Age § 408.413 How do we evaluate the evidence...

Design Evolution Study - Aging Options

DOE Office of Scientific and Technical Information (OSTI.GOV)

P. McDaniel

The purpose of this study is to identify options and issues for aging commercial spent nuclear fuel received for disposal at the Yucca Mountain Mined Geologic Repository. Some early shipments of commercial spent nuclear fuel to the repository may be received with high-heat-output (younger) fuel assemblies that will need to be managed to meet thermal goals for emplacement. The capability to age as much as 40,000 metric tons of heavy metal of commercial spent nuclear he1 would provide more flexibility in the design to manage this younger fuel and to decouple waste receipt and waste emplacement. The following potential agingmore » location options are evaluated: (1) Surface aging at four locations near the North Portal; (2) Subsurface aging in the permanent emplacement drifts; and (3) Subsurface aging in a new subsurface area. The following aging container options are evaluated: (1) Complete Waste Package; (2) Stainless Steel inner liner of the waste package; (3) Dual Purpose Canisters; (4) Multi-Purpose Canisters; and (5) New disposable canister for uncanistered commercial spent nuclear fuel. Each option is compared to a ''Base Case,'' which is the expected normal waste packaging process without aging. A Value Engineering approach is used to score each option against nine technical criteria and rank the options. Open issues with each of the options and suggested future actions are also presented. Costs for aging containers and aging locations are evaluated separately. Capital costs are developed for direct costs and distributable field costs. To the extent practical, unit costs are presented. Indirect costs, operating costs, and total system life cycle costs will be evaluated outside of this study. Three recommendations for aging commercial spent nuclear fuel--subsurface, surface, and combined surface and subsurface are presented for further review in the overall design re-evaluation effort. Options that were evaluated but not recommended are: subsurface aging in a new subsurface area (high cost); surface aging in the complete waste package (risk to the waste package and impact on the Waste Handling Facility); and aging in the stainless steel liner (impact on the waste package design and new high risk operations added to the waste packaging process). The selection of a design basis for aging will be made in conjunction with the other design re-evaluation studies.« less

The aging physician and surgeon.

PubMed

Sataloff, Robert T; Hawkshaw, Mary; Kutinsky, Joshua; Maitz, Edward A

2016-01-01

As the population of aging physicians increases, methods of assessing physicians' cognitive function and predicting clinically significant changes in clinical performance become increasingly important. Although several approaches have been suggested, no evaluation system is accepted or utilized widely. This article reviews literature using MEDLINE, PubMed, and other sources. Articles discussing the problems of geriatric physicians are summarized, stressing publications that proposed methods of evaluation. Selected literature on evaluating aging pilots also was reviewed, and potential applications for physician evaluation are proposed. Neuropsychological cognitive test protocols were summarized, and a reduced evaluation protocol is proposed for interdisciplinary longitudinal research. Although there are several articles evaluating cognitive function in aging physicians and aging pilots, and although a few institutions have instituted cognitive evaluation, there are no longitudinal data assessing cognitive function in physicians over time or correlating them with performance. Valid, reliable testing of cognitive function of physicians is needed. In order to understand its predictive value, physicians should be tested over time starting when they are young, and results should be correlated with physician performance. Early testing is needed to determine whether cognitive deficits are age-related or long-standing. A multi-institutional study over many years is proposed. Additional assessments of other factors such as manual dexterity (perhaps using simulators) and physician frailty are recommended.

Active Aging Promotion: Results from the Vital Aging Program

PubMed Central

Caprara, Mariagiovanna; Molina, María Ángeles; Schettini, Rocío; Santacreu, Marta; Orosa, Teresa; Mendoza-Núñez, Víctor Manuel; Rojas, Macarena; Fernández-Ballesteros, Rocío

2013-01-01

Active aging is one of the terms in the semantic network of aging well, together with others such as successful, productive, competent aging. All allude to the new paradigm in gerontology, whereby aging is considered from a positive perspective. Most authors in the field agree active aging is a multidimensional concept, embracing health, physical and cognitive fitness, positive affect and control, social relationships and engagement. This paper describes Vital Aging, an individual active aging promotion program implemented through three modalities: Life, Multimedia, and e-Learning. The program was developed on the basis of extensive evidence about individual determinants of active aging. The different versions of Vital Aging are described, and four evaluation studies (both formative and summative) are reported. Formative evaluation reflected participants' satisfaction and expected changes; summative evaluations yielded some quite encouraging results using quasi-experimental designs: those who took part in the programs increased their physical exercise, significantly improved their diet, reported better memory, had better emotional balance, and enjoyed more cultural, intellectual, affective, and social activities than they did before the course, thus increasing their social relationships. These results are discussed in the context of the common literature within the field and, also, taking into account the limitations of the evaluations accomplished. PMID:23476644

Teaching and Learning About Aging. Evaluation Report.

ERIC Educational Resources Information Center

Peters, Eileen

This evaluation study determined the extent to which teachers and students involved with the Teaching and Learning About Aging (TLA) project experienced cognitive growth and attitudinal change. The major purpose of the TLA project was to help students understand aging and related issues and to foster more positive attitudes toward aging and older…

Evaluation of special surface treatment aged using UV, phase I.

DOT National Transportation Integrated Search

2011-08-01

Research was undertaken to evaluate the effectiveness of Tensars specialty polymer cement slurry : (coating) in reducing aging of asphalt binders and mixtures. The study was also aimed at evaluating the effect of this : material on performance cha...

The influence of age on posterior pelvic floor dysfunction in women with obstructed defecation syndrome.

PubMed

Murad-Regadas, S M; Rodrigues, L V; Furtado, D C; Regadas, F S P; Olivia da S Fernandes, G; Regadas Filho, F S P; Gondim, A C; de Paula Joca da Silva, R

2012-06-01

Knowledge of risk factors is particularly useful to prevent or manage pelvic floor dysfunction but although a number of such factors have been proposed, results remain inconsistent. The purpose of this study was to evaluate the impact of aging on the incidence of posterior pelvic floor disorders in women with obstructed defecation syndrome evaluated using echodefecography. A total of 334 patients with obstructed defecation were evaluated using echodefecography in order to quantify posterior pelvic floor dysfunction (rectocele, intussusception, mucosal prolapse, paradoxical contraction or non-relaxation of the puborectalis muscle, and grade III enterocele/sigmoidocele). Patients were grouped according to the age (Group I = patients up to 50 years of age; Group II = patients over 50 years of age) to evaluate the isolated and associated incidence of dysfunctions. To evaluate the relationship between dysfunction and age-related changes, patients were also stratified into decades. Group I included 196 patients and Group II included 138. The incidence of significant rectocele, intussusception, rectocele associated with intussusception, rectocele associated with mucosal prolapse and 3 associated disorders was higher in Group II, whereas anismus was more prevalent in Group I. The incidence of significant rectocele, intussusception, mucosal prolapse and grade III enterocele/sigmoidocele was found to increase with age. Conversely, anismus decreased with age. Aging was shown to influence the incidence of posterior pelvic floor disorders (rectocele, intussusception, mucosa prolapse and enterocele/sigmoidocele), but not the incidence of anismus, in women with obstructed defecation syndrome.

Evaluation of thermally-aged carbon fiber/epoxy composites using acoustic emission, electrical resistance, contact angle and thermogram

NASA Astrophysics Data System (ADS)

Park, J. M.; Shin, P. S.; Kim, J. H.; Park, H. S.; Baek, Y. M.; DeVries, K. L.

2018-03-01

Interfacial and mechanical properties of thermal aged carbon fiber reinforced epoxy composites (CFRP) were evaluated using acoustic emission (AE), electrical resistance (ER), contact angle (CA) and thermogram measurements. Unidirectional (UD)-composites were aged at 200, 300, and 400 °C to produce different interfacial conditions. The interfacial degradation was identified by Fourier transform infrared (FT-IR) spectroscopy after different thermal aging. AE and ER of UD composites were measured along 0, 30, 60 and 90 °. Changes in wavespeed, with thermal aging, were calculated using wave travel time from AE source to AE sensor and the changes in ER were measured. For a thermogram evaluation, the composites were laid upon on a hotplate and the increase in the surface temperature was measured. Static contact angle were measured after different thermal aging and elapsed times to evaluate wettability. Interlaminar shear Strength (ILSS) and tensile strength at transverse direction tests were also performed to explore the effects of thermal aging on mechanical and interfacial properties. While thermal aging of CFRPs was found to affect all these properties, the changes were particularly evident at 400 °C.

[Present possibilities of age determination in forensic medicine with emphasis on the importance of measurement of D- and L- forms of aspartic acid. I. An overview].

PubMed

Pilin, A; Pudil, F; Gross, R; Herrmannová, M

1997-02-01

Evaluation of age of unknown deceased persons belongs to the most important ways to identification. For the time being, morphological methods are used, namely evaluation of age according to Gustafson's method from tooth grindings or by macroscopical estimation of abrasion, transparency of root dentine, alveolar atrophy and number of missing teeth. Evaluation of the data can be influenced by an individual failure and experience showed an age related decrease of precision. Recently, some papers occurred estimating a relation of D, L-forms of aspartic acid which depends on the age with a significant precision.

But do you think I’m cool? Developmental differences in striatal recruitment during direct and reflected social self-evaluations

PubMed Central

Jankowski, Kathryn F.; Moore, William E.; Merchant, Junaid S.; Kahn, Lauren E.; Pfeifer, Jennifer H.

2015-01-01

The current fMRI study investigated the neural foundations of evaluating oneself and others during early adolescence and young adulthood. Eighteen early adolescents (ages 11–14, M = 12.6) and 19 young adults (ages 22–31, M = 25.6) evaluated if academic, physical, and social traits described themselves directly (direct self-evaluations), described their best friend directly (direct other-evaluations), described themselves from their best friend’s perspective (reflected self-evaluations), or in general could change over time (control malleability-evaluations). Compared to control evaluations, both adolescents and adults recruited cortical midline structures during direct and reflected self-evaluations, as well as during direct other-evaluations, converging with previous research. However, unique to this study was a significant three-way interaction between age group, evaluative perspective, and domain within bilateral ventral striatum. Region of interest analyses demonstrated a significant evaluative perspective by domain interaction within the adolescent sample only. Adolescents recruited greatest bilateral ventral striatum during reflected social self-evaluations, which was positively correlated with age and pubertal development. These findings suggest that reflected social self-evaluations, made from the inferred perspective of a close peer, may be especially self-relevant, salient, or rewarding to adolescent self-processing – particularly during the progression through adolescence – and this feature persists into adulthood. PMID:24582805

But do you think I'm cool? Developmental differences in striatal recruitment during direct and reflected social self-evaluations.

PubMed

Jankowski, Kathryn F; Moore, William E; Merchant, Junaid S; Kahn, Lauren E; Pfeifer, Jennifer H

2014-04-01

The current fMRI study investigates the neural foundations of evaluating oneself and others during early adolescence and young adulthood. Eighteen early adolescents (ages 11-14, M=12.6) and 19 young adults (ages 22-31, M=25.6) evaluated whether academic, physical, and social traits described themselves directly (direct self-evaluations), described their best friend directly (direct other-evaluations), described themselves from their best friend's perspective (reflected self-evaluations), or in general could change over time (control malleability-evaluations). Compared to control evaluations, both adolescents and adults recruited cortical midline structures during direct and reflected self-evaluations, as well as during direct other-evaluations, converging with previous research. However, unique to this study was a significant three-way interaction between age group, evaluative perspective, and domain within bilateral ventral striatum. Region of interest analyses demonstrated a significant evaluative perspective by domain interaction within the adolescent sample only. Adolescents recruited greatest bilateral ventral striatum during reflected social self-evaluations, which was positively correlated with age and pubertal development. These findings suggest that reflected social self-evaluations, made from the inferred perspective of a close peer, may be especially self-relevant, salient, or rewarding to adolescent self-processing--particularly during the progression through adolescence - and this feature persists into adulthood. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

A reexamination of age-related variation in body weight and morphometry of Maryland nutria

USGS Publications Warehouse

Sherfy, M.H.; Mollett, T.A.; McGowan, K.R.; Daugherty, S.L.

2006-01-01

Age-related variation in morphometry has been documented for many species. Knowledge of growth patterns can be useful for modeling energetics, detecting physiological influences on populations, and predicting age. These benefits have shown value in understanding population dynamics of invasive species, particularly in developing efficient control and eradication programs. However, development and evaluation of descriptive and predictive models is a critical initial step in this process. Accordingly, we used data from necropsies of 1,544 nutria (Myocastor coypus) collected in Maryland, USA, to evaluate the accuracy of previously published models for prediction of nutria age from body weight. Published models underestimated body weights of our animals, especially for ages <3. We used cross-validation procedures to develop and evaluate models for describing nutria growth patterns and for predicting nutria age. We derived models from a randomly selected model-building data set (n = 192-193 M, 217-222 F) and evaluated them with the remaining animals (n = 487-488 M, 642-647 F). We used nonlinear regression to develop Gompertz growth-curve models relating morphometric variables to age. Predicted values of morphometric variables fell within the 95% confidence limits of their true values for most age classes. We also developed predictive models for estimating nutria age from morphometry, using linear regression of log-transformed age on morphometric variables. The evaluation data set corresponded with 95% prediction intervals from the new models. Predictive models for body weight and length provided greater accuracy and less bias than models for foot length and axillary girth. Our growth models accurately described age-related variation in nutria morphometry, and our predictive models provided accurate estimates of ages from morphometry that will be useful for live-captured individuals. Our models offer better accuracy and precision than previously published models, providing a capacity for modeling energetics and growth patterns of Maryland nutria as well as an empirical basis for determining population age structure from live-captured animals.

Evaluation of persons of varying ages.

PubMed

Stolte, J F

1996-06-01

Dual coding theory (Paivio, 1986) suggests that communicating a stimulus person's age verbally/abstractly through words and numbers arouses little feeling and has little effect on the way others evaluate her or him, whereas communicating age nonverbally/concretely through facial photographs arouses more feeling and has a greater impact on evaluation. Two experiments reported in this article, involving U.S. students and incorporating techniques developed in prior research by Levin (1988) strongly support these theoretical expectations.

Evaluation of Persons of Varying Ages.

ERIC Educational Resources Information Center

Stolte, John F.

1996-01-01

Reviews two experiments that strongly support dual coding theory. Dual coding theory holds that communicating concretely (tactile, auditory, or visual stimuli) affects evaluative thinking stronger than communicating abstractly through words and numbers. The experiments applied this theory to the realm of age and evaluation. (MJP)

Brazilian version of the Protocole Montréal d'Evaluation de la Communication (Protocole MEC): normative and reliability data.

PubMed

Fonseca, Rochele Paz; Joanette, Yves; Côté, Hélène; Ska, Bernadette; Giroux, Francine; Fachel, Jandyra Maria Guimarães; Damasceno Ferreira, Gabriela; Parente, Maria Alice de Mattos Pimenta

2008-11-01

The lack of standardized instruments to evaluate communication disorders related to the right hemisphere was verified. A new evaluation tool was developed: Protocole Montréal d'Evaluation de la Communication--Protocole MEC, adapted to Brazilian Portuguese--Bateria Montreal de Avaliação da Comunicação--Bateria MAC (Montreal Evaluation of Communication Battery). The purpose was to present stratified normative data by age and educational level, and to verify the reliability parameters of the MEC Battery. 300 individuals, between the ages of 19 and 75 years, and levels of formal education between 2 and 35 years, participated in this study. They were divided equally into six normative groups, according to three age categories (young adults, intermediary age, and seniors) and two educational levels (low and high). Two procedures were used to check reliability: Cronbach alpha and reliability between evaluators, Results were established at the 10th percentile, and an alert point per task for each normative group. Cronbach's alpha was, in general, between .70 and .90 and the average rate of agreement between evaluators varied from .62 to .94. Standards of age and education were established. The reliability of this instrument was verified. The psychometric legitimization of the MEC Battery will contribute to the diagnostic process for communicative disorders.

Oppositional Defiance, Moral Reasoning and Moral Value Evaluation as Predictors of Self-Reported Juvenile Delinquency

ERIC Educational Resources Information Center

Beerthuizen, Marinus G. C. J.; Brugman, Daniel; Basinger, Karen S.

2013-01-01

This study investigated the relationships among oppositional defiant attitudes, moral reasoning, moral value evaluation and self-reported delinquent behaviour in adolescents ("N" = 351, "M"[subscript AGE] = 13.8 years, "SD"[subscript AGE] = 1.1). Of particular interest were the moderating effects of age, educational…

Considerations in the Design of Clinical Trials for Cognitive Aging

PubMed Central

Brinton, Roberta Diaz; Katz, Russell; Petersen, Ronald C.; Negash, Selam; Mungas, Dan; Aisen, Paul S.

2012-01-01

What will it take to develop interventions for the treatment of age-related cognitive decline? Session V of the Summit provided perspectives on the design of clinical trials to evaluate promising but unproven interventions, and some of the steps needed to accelerate the discovery and evaluation of promising treatments. It considered strategies to further characterize the biological and cognitive changes associated with normal aging and their translation into the development of new treatments. It provided regulatory, scientific, and clinical perspectives about neurocognitive aging treatments, their potential benefits and risks, and the strategies and endpoints needed to evaluate them in the most rapid, rigorous, and clinically meaningful way. It considered lessons learned from the study of Alzheimer's disease, the promising roles of biomarkers in neurocognitive aging research, and ways to help galvanize the scientific study and treatment of neurocognitive aging. PMID:22573913

Considerations in the design of clinical trials for cognitive aging.

PubMed

Reiman, Eric M; Brinton, Roberta Diaz; Katz, Russell; Petersen, Ronald C; Negash, Selam; Mungas, Dan; Aisen, Paul S

2012-06-01

What will it take to develop interventions for the treatment of age-related cognitive decline? Session V of the Summit provided perspectives on the design of clinical trials to evaluate promising but unproven interventions, and some of the steps needed to accelerate the discovery and evaluation of promising treatments. It considered strategies to further characterize the biological and cognitive changes associated with normal aging and their translation into the development of new treatments. It provided regulatory, scientific, and clinical perspectives about neurocognitive aging treatments, their potential benefits and risks, and the strategies and endpoints needed to evaluate them in the most rapid, rigorous, and clinically meaningful way. It considered lessons learned from the study of Alzheimer's disease, the promising roles of biomarkers in neurocognitive aging research, and ways to help galvanize the scientific study and treatment of neurocognitive aging.

Stump sprouting potential of oaks in Missouri Ozark forests managed by even- and uneven-aged silviculture

Treesearch

Daniel C. Dey; Randy G. Jensen

2002-01-01

We evaluated the stump sprouting potential of white oak, black oak, and scarlet oak in relation to tree age, stem diameter, and overstory density in Ozark forests managed by even-aged and uneven-aged silvicultural systems. In eastern North America, few studies have evaluated the influence of a forest canopy on the potential of hardwood stumps to sprout and contribute...

The etiology of mathematical self-evaluation and mathematics achievement: understanding the relationship using a cross-lagged twin study from age 9 to 12

PubMed Central

Luo, Yu L.L.; Kovas, Yulia; Haworth, Claire M.A.; Plomin, Robert

2011-01-01

The genetic and environmental origins of individual differences in mathematical self-evaluation over time and its association with later mathematics achievement were investigated in a UK sample of 2138 twin pairs at ages 9 and 12. Self-evaluation indexed how good children think they are at mathematical activities and how much they like those activities. Mathematics achievement was assessed by teachers based on UK National Curriculum standards. At both ages self-evaluation was approximately 40% heritable, with the rest of the variance explained by non-shared environment. The results also suggested moderate reciprocal associations between self-evaluation and mathematics achievement across time, with earlier self-evaluation predicting later performance and earlier performance predicting later self-evaluation. These cross-lagged relationships were genetically rather than environmentally mediated. PMID:22102781

Evaluation of dental care and the prevalence of tooth decay among middle-aged and elderly population of Kaunas city.

PubMed

Zubiene, Jurate; Milciuviene, Simona; Klumbiene, Jurate

2009-01-01

The aim of the study was to evaluate the prevalence and the intensity of tooth decay among the middle-aged and elderly population of Kaunas, city, and to assess the need for prostheses as well as the possibilities for oral care. During 2006-2008, we studied 1,141 inhabitants of Kaunas city; the subjects' age was 45-72 years. Oral evaluation technique proposed by the WHO was used in the investigation. We evaluated the prevalence of tooth decay, and its intensity was evaluated using the DMF-T index. We also evaluated dental prostheses, the need for prosthetics, and asked the subjects how they took care of their oral health. The prevalence of tooth decay among middle-aged and elderly population of Kaunas city was 99.9%. The DMF-T index was 21.01+/-0.3 in the age group of 45-54 years, 23.52+/-0.4 - in the age group of 55-64 years, and 25.63+/-0.3 - in the elderly subjects. Full removable dentures were found in 14.0% of the elderly subjects, while 1.0% of the middle-aged subjects and 1.2% of the elderly subjects required full dentures. 57.7% of the subjects aged 45-54 years, 53.1% of the subjects aged 55-64 years, and 43.4% of the elderly subjects brushed their teeth twice daily. The intensity of tooth decay in middle-aged and elderly population of Kaunas city significantly increased with age (21.01-25.63). A relationship was found between oral hygiene status and the DMF-T index. In the middle-aged and elderly population of Kaunas city, the intensity of tooth decay was significantly lower (DMF-T 23.04%) among those who brushed their teeth twice daily than among those who brushed their teeth once daily or less frequently (DMF-T 24.01%). Reduction of the prevalence of tooth decay among middle-aged and elderly population of Kaunas city necessitates alterations in people's attitudes towards dental care, implementation of suitable hygiene habits, and creation and implementation of the dental disease prevention program for adults and the elderly, based on the strategy proposed by the World Health Organization.

Guidelines for the Evaluation of Dementia and Age-Related Cognitive Change

ERIC Educational Resources Information Center

American Psychologist, 2012

2012-01-01

Dementia in its many forms is a leading cause of functional limitation among older adults worldwide and will continue to ascend in global health importance as populations continue to age and effective cures remain elusive. The following guidelines were developed for psychologists who perform evaluations of dementia and age-related cognitive…

77 FR 35682 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Evaluation...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-14

... Collection Activities; Submission for OMB Review; Comment Request; Evaluation of the Aging and Disability.... The data collection associated with the Evaluation for the Aging and Disability Resource Center (ADRC... consumers, who access ADRCs, as compared to consumers who access other systems, report that the experience...

Dissecting the voice: Health professions students' perceptions of instructor age and gender in an online environment and the impact on evaluations for faculty.

PubMed

Doubleday, Alison F; Lee, Lisa M J

2016-11-01

Gender and age bias is well-documented in academia with many studies demonstrating bias in students' evaluations of instructors. Failure of an instructor to meet gender or age-based expectations can translate to lower scores or negative comments on evaluations. While there is some evidence of bias in students' evaluations of online instructors, current studies have not fully examined the relationship between bias and instructor vocal characteristics. First-year dental students at two institutions were randomly assigned one of four videos on spinal cord anatomy to view. Videos contained identical content but were narrated by individuals of different gender and age (younger man, younger woman, older man, older woman). Students completed a content-based prequiz, watched the video, completed a postquiz, and answered a questionnaire evaluating the video and instructor. Students at Institution A rated the younger man and younger woman highest for nearly every evaluation category. At Institution B students rated the older man and younger woman highest. Results reveal that the older woman's voice received the lowest rankings for nearly every question in both samples. This report confirms the presence of gender and age bias in student evaluations of instructors in an online environment and demonstrates that bias may surface in response to vocal characteristics. Bias may impact older women more significantly than other groups. Differences in results from Institution A and Institution B suggest that factors affecting student perceptions of instructors, and the roles that gender and age bias may play in student evaluations, are complex and may be contextual. Anat Sci Educ 9: 537-544. © 2016 American Association of Anatomists. © 2016 American Association of Anatomists.

Drosophila melanogaster as a model system for the evaluation of anti-aging compounds.

PubMed

Jafari, Mahtab

2010-01-01

Understanding the causes of aging is a complex problem due to the multiple factors that influence aging, which include genetics, environment, metabolism and reproduction, among others. These multiple factors create logistical difficulties in the evaluation of anti-aging agents. There is a need for good model systems to evaluate potential anti-aging compounds. The model systems used should represent the complexities of aging in humans, so that the findings may be extrapolated to human studies, but they should also present an opportunity to minimize the variables so that the experimental results can be accurately interpreted. In addition to positively affecting lifespan, the impact of the compound on the physiologic confounders of aging, including fecundity and the health span--the period of life where an organism is generally healthy and free from serious or chronic illness--of the model organism needs to be evaluated. Fecundity is considered a major confounder of aging in fruit flies. It is well established that female flies that are exposed to toxic substances typically reduce their dietary intake and their reproductive output and display an artifactual lifespan extension. As a result, drugs that achieve longevity benefits by reducing fecundity as a result of diminished food intake are probably not useful candidates for eventual treatment of aging in humans and should be eliminated during the screening process. Drosophila melanogaster provides a suitable model system for the screening of anti-aging compounds as D. melanogaster and humans have many conserved physiological and biological pathways. In this paper, I propose an algorithm to screen anti-aging compounds using Drosophila melanogaster as a model system.

Drinking-Age Laws: An Evaluation Synthesis of Their Impact on Highway Safety. Report to the Chairman, Subcommittee on Investigations and Oversight, Committee on Public Works and Transportation, House of Representatives.

ERIC Educational Resources Information Center

General Accounting Office, Washington, DC. Program Evaluation and Methodology Div.

This study examined existing evaluations of drinking-age laws to determine the extent to which they provide empirical support for federal and state initiatives to change the legal drinking age. It specifically examined the effects that raising the minimum drinking age has had on traffic accidents, beverage alcohol consumption, driving after…

Montreal Communication Evaluation Battery--Portuguese version: age and education effects.

PubMed

Kerr, Mônica de Souza; Pagliarin, Karina Carlesso; Mineiro, Ana; Ferré, Perrine; Joanette, Yves; Fonseca, Rochele Paz

2015-01-01

To verify age and education effects on communication performance of healthy adults in the Montreal Communication Evaluation Battery, Portuguese version (MAC-PT). The sample comprised 90 healthy adults from Portugal, European Portuguese speakers, divided into nine groups according to educational level (4-9, 10-13, and > 13 years of formal schooling) and age (19-40, 41-64, and 65-80 years). The influence of age and education was assessed by comparing mean scores between groups, using a two-way analysis of variance followed by Bonferroni post hoc tests (p ≤ 0.05). The results showed that participants' performance was influenced by age in pragmatic-inferential, discursive, and prosodic tasks. Education had the greatest influence on the performance in all processes evaluated by the MAC-PT. Age and education seem to influence the communicative performance and should be considered in the assessment of neurological patients.

Evaluation of left-right difference of impulse in impact forces at stance phase: comparison of measurements on flat land and stairs

PubMed Central

Tasato, Hiroshi; Kida, Noriyuki

2018-01-01

[Purpose] The purpose of this study was to investigate the measurement method and parameters to simply evaluate the condition of the knee that are necessary for preventing locomotive syndrome as advocated by the Japan Orthopedic Association. [Subjects and Methods] The subjects installed acceleration sensors in lateral condyles of the tibia and measured acceleration and load under the conditions of walking on a flat ground and walking using stairs; the difference between the impulse of impact forces (acceleration × load) of the two knees was defined as a simple evaluation parameter. [Results] Simple evaluation parameters were not correlated with age during walking on a flat ground, but during walking using stairs, it was almost flat up to the age of 20–40 years, and after the age of 49 years, based on the quadratic curve approximation (R2=0.99), a correlation of simple evaluation parameters with age could be confirmed. [Conclusion] The simple evaluation parameter during walking using stairs was highly correlated with age, suggesting a contribution to preventing locomotive syndrome by improving reliability. In the future, we plan to improve reliability by increasing the data, and establish it as a simple evaluation parameter that can be used for preventing locomotive syndrome in elderly people and those with KL classification grades 0–1. PMID:29706699

Diversity training for the community aged care workers: A conceptual framework for evaluation.

PubMed

Appannah, Arti; Meyer, Claudia; Ogrin, Rajna; McMillan, Sally; Barrett, Elizabeth; Browning, Colette

2017-08-01

Older Australians are an increasingly diverse population, with variable characteristics such as culture, sexual orientation, socioeconomic status, and physical capabilities potentially influencing their participation in healthcare. In response, community aged care workers may need to increase skills and uptake of knowledge into practice regarding diversity through appropriate training interventions. Diversity training (DT) programs have traditionally existed in the realm of business, with little research attention devoted to scientifically evaluating the outcomes of training directed at community aged care workers. A DT workshop has been developed for community aged care workers, and this paper focuses on the construction of a formative evaluative framework for the workshop. Key evaluation concepts and measures relating to DT have been identified in the literature and integrated into the framework, focusing on five categories: Training needs analysis; Reactions; Learning outcomes, Behavioural outcomes and Results The use of a mixed methods approach in the framework provides an additional strength, by evaluating long-term behavioural change and improvements in service delivery. As little is known about the effectiveness of DT programs for community aged care workers, the proposed framework will provide an empirical and consistent method of evaluation, to assess their impact on enhancing older people's experience of healthcare. Copyright © 2017 Elsevier Ltd. All rights reserved.

The effect of accelerated aging on the wear of UHMWPE.

PubMed

Sakoda, H; Fisher, J; Lu, S; Buchanan, F

2001-01-01

Oxidative degradation of UHMWPE has been found to be a cause of elevated wear rate of the polymer in total joint replacement leading to failure of these devices. In order to evaluate long term stability of polymers, various accelerated aging methods have been developed. In this study, wear rates of shelf aged UHMWPE and "accelerated aged" UHMWPE were compared using a multi-directional pin-on-plate wear test machine in order to evaluate the effect of the accelerated aging on wear. Wear factors of the aged materials were found to depend on their density, which is a measure of oxidation level. Finally, accelerated aging was calibrated against shelf aging in terms of wear rate. Copyright 2001 Kluwer Academic Publishers

The Evaluation of a Personal Narrative Language Intervention for School-Age Children with Down Syndrome

ERIC Educational Resources Information Center

Finestack, Lizbeth; O'Brien, Katy H.; Hyppa-Martin, Jolene; Lyrek, Kristen A.

2017-01-01

The purpose of this study was to evaluate the feasibility of an intervention focused on improving personal narrative skills of school-age children with Down syndrome (DS) using an approach involving visual supports. Four females with DS, ages 10 through 15 years, participated in this multiple baseline across participants single-subject…

Recommendations for the treatment of aging in standard technical specifications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orton, R.D.; Allen, R.P.

1995-09-01

As part of the US Nuclear Regulatory Commission`s Nuclear Plant Aging Research Program, Pacific Northwest Laboratory (PNL) evaluated the standard technical specifications for nuclear power plants to determine whether the current surveillance requirements (SRs) were effective in detecting age-related degradation. Nuclear Plant Aging Research findings for selected systems and components were reviewed to identify the stressors and operative aging mechanisms and to evaluate the methods available to detect, differentiate, and trend the resulting aging degradation. Current surveillance and testing requirements for these systems and components were reviewed for their effectiveness in detecting degraded conditions and for potential contributions to prematuremore » degradation. When the current surveillance and testing requirements appeared ineffective in detecting aging degradation or potentially could contribute to premature degradation, a possible deficiency in the SRs was identified that could result in undetected degradation. Based on this evaluation, PNL developed recommendations for inspection, surveillance, trending, and condition monitoring methods to be incorporated in the SRs to better detect age- related degradation of these selected systems and components.« less

Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years--Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2012.

PubMed

Christensen, Deborah L; Baio, Jon; Van Naarden Braun, Kim; Bilder, Deborah; Charles, Jane; Constantino, John N; Daniels, Julie; Durkin, Maureen S; Fitzgerald, Robert T; Kurzius-Spencer, Margaret; Lee, Li-Ching; Pettygrove, Sydney; Robinson, Cordelia; Schulz, Eldon; Wells, Chris; Wingate, Martha S; Zahorodny, Walter; Yeargin-Allsopp, Marshalyn

2016-04-01

Autism spectrum disorder (ASD). 2012. The Autism and Developmental Disabilities Monitoring (ADDM) Network is an active surveillance system that provides estimates of the prevalence and characteristics of ASD among children aged 8 years whose parents or guardians reside in 11 ADDM Network sites in the United States (Arkansas, Arizona, Colorado, Georgia, Maryland, Missouri, New Jersey, North Carolina, South Carolina, Utah, and Wisconsin). Surveillance to determine ASD case status is conducted in two phases. The first phase consists of screening and abstracting comprehensive evaluations performed by professional service providers in the community. Data sources identified for record review are categorized as either 1) education source type, including developmental evaluations to determine eligibility for special education services or 2) health care source type, including diagnostic and developmental evaluations. The second phase involves the review of all abstracted evaluations by trained clinicians to determine ASD surveillance case status. A child meets the surveillance case definition for ASD if one or more comprehensive evaluations of that child completed by a qualified professional describes behaviors that are consistent with the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision diagnostic criteria for any of the following conditions: autistic disorder, pervasive developmental disorder-not otherwise specified (including atypical autism), or Asperger disorder. This report provides ASD prevalence estimates for children aged 8 years living in catchment areas of the ADDM Network sites in 2012, overall and stratified by sex, race/ethnicity, and the type of source records (education and health records versus health records only). In addition, this report describes the proportion of children with ASD with a score consistent with intellectual disability on a standardized intellectual ability test, the age at which the earliest known comprehensive evaluation was performed, the proportion of children with a previous ASD diagnosis, the specific type of ASD diagnosis, and any special education eligibility classification. For 2012, the combined estimated prevalence of ASD among the 11 ADDM Network sites was 14.6 per 1,000 (one in 68) children aged 8 years. Estimated prevalence was significantly higher among boys aged 8 years (23.6 per 1,000) than among girls aged 8 years (5.3 per 1,000). Estimated ASD prevalence was significantly higher among non-Hispanic white children aged 8 years (15.5 per 1,000) compared with non-Hispanic black children (13.2 per 1,000), and Hispanic (10.1 per 1,000) children aged 8 years. Estimated prevalence varied widely among the 11 ADDM Network sites, ranging from 8.2 per 1,000 children aged 8 years (in the area of the Maryland site where only health care records were reviewed) to 24.6 per 1,000 children aged 8 years (in New Jersey, where both education and health care records were reviewed). Estimated prevalence was higher in surveillance sites where education records and health records were reviewed compared with sites where health records only were reviewed (17.1 per 1,000 and 10.7 per 1,000 children aged 8 years, respectively; p<0.05). Among children identified with ASD by the ADDM Network, 82% had a previous ASD diagnosis or educational classification; this did not vary by sex or between non-Hispanic white and non-Hispanic black children. A lower percentage of Hispanic children (78%) had a previous ASD diagnosis or classification compared with non-Hispanic white children (82%) and with non-Hispanic black children (84%). The median age at earliest known comprehensive evaluation was 40 months, and 43% of children had received an earliest known comprehensive evaluation by age 36 months. The percentage of children with an earliest known comprehensive evaluation by age 36 months was similar for boys and girls, but was higher for non-Hispanic white children (45%) compared with non-Hispanic black children (40%) and Hispanic children (39%). Overall estimated ASD prevalence was 14.6 per 1,000 children aged 8 years in the ADDM Network sites in 2012. The higher estimated prevalence among sites that reviewed both education and health records suggests the role of special education systems in providing comprehensive evaluations and services to children with developmental disabilities. Disparities by race/ethnicity in estimated ASD prevalence, particularly for Hispanic children, as well as disparities in the age of earliest comprehensive evaluation and presence of a previous ASD diagnosis or classification, suggest that access to treatment and services might be lacking or delayed for some children. The ADDM Network will continue to monitor the prevalence and characteristics of ASD among children aged 8 years living in selected sites across the United States. Recommendations from the ADDM Network include enhancing strategies to 1) lower the age of first evaluation of ASD by community providers in accordance with the Healthy People 2020 goal that children with ASD are evaluated by age 36 months and begin receiving community-based support and services by age 48 months; 2) reduce disparities by race/ethnicity in identified ASD prevalence, the age of first comprehensive evaluation, and presence of a previous ASD diagnosis or classification; and 3) assess the effect on ASD prevalence of the revised ASD diagnostic criteria published in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.

Evaluation of a Community-Based Aging Intervention Program

ERIC Educational Resources Information Center

Hsu, Hui-Chuan; Wang, Chun-Hou; Chen, Yi-Chun; Chang, Ming-Chen; Wang, Jean

2010-01-01

This study evaluated the outcome and process of a community-based aging intervention program for the elderly in Taiwan. The program included education on nutrition and dietary behavior and on physical activities. Outcome and process evaluations were conducted. The program may have had some effects on decreasing some dietary behavioral problems and…

Evaluating Learning in the 21st Century: A Digital Age Learning Matrix

ERIC Educational Resources Information Center

Starkey, Louise

2011-01-01

If the purpose of secondary schooling is to educate the upcoming generation to become active participants in society, evaluation of teaching and learning in the information-rich digital age should be underpinned by relevant theories and models. This article describes an evaluation tool developed using emerging ideas about knowledge creation and…

Prevalence, Formation, Maintenance, and Evaluation of Interdisciplinary Student Aging Interest Groups

ERIC Educational Resources Information Center

Jones, Katherine J.; Vandenberg, Edward V.; Bottsford, Lisa

2011-01-01

The authors describe the prevalence, formation, maintenance, and evaluation of student aging interest groups. They conducted a cross-sectional electronic survey of the 46 academic medical centers funded by the Donald W. Reynolds Foundation. To evaluate their group of approximately 50 students, the authors conducted an electronic pretest and…

Language evaluation protocol for children aged 2 months to 23 months: analysis of sensitivity and specificity.

PubMed

Labanca, Ludimila; Alves, Cláudia Regina Lindgren; Bragança, Lidia Lourenço Cunha; Dorim, Diego Dias Ramos; Alvim, Cristina Gonçalves; Lemos, Stela Maris Aguiar

2015-01-01

To establish cutoff points for the analysis of the Behavior Observation Form (BOF) of children in the ages of 2 to 23 months and evaluate the sensitivity and specificity by age group and domains (Emission, Reception, and Cognitive Aspects of Language). The sample consisted of 752 children who underwent BOF. Each child was classified as having appropriate language development for the age or having possible risk of language impairment. Performance Indicators (PI) were calculated in each domain as well as the overall PI in all domains. The values for sensitivity and specificity were also calculated. The cutoff points for possible risk of language impairment for each domain and each age group were obtained using the receiver operating characteristics curve. The results of the study revealed that one-third of the assessed children have a risk of language impairment in the first two years of life. The analysis of BOF showed high sensitivity (>90%) in all categories and in all age groups; however, the chance of false-positive results was higher than 20% in the majority of aspects evaluated. It was possible to establish the cutoff points for all categories and age groups with good correlation between sensitivity and specificity, except for the age group of 2 to 6 months. This study provides important contributions to the discussion on the evaluation of the language development of children younger than 2 years.

Evaluation and recognition of skin images with aging by support vector machine

NASA Astrophysics Data System (ADS)

Hu, Liangjun; Wu, Shulian; Li, Hui

2016-10-01

Aging is a very important issue not only in dermatology, but also cosmetic science. Cutaneous aging involves both chronological and photoaging aging process. The evaluation and classification of aging is an important issue with the medical cosmetology workers nowadays. The purpose of this study is to assess chronological-age-related and photo-age-related of human skin. The texture features of skin surface skin, such as coarseness, contrast were analyzed by Fourier transform and Tamura. And the aim of it is to detect the object hidden in the skin texture in difference aging skin. Then, Support vector machine was applied to train the texture feature. The different age's states were distinguished by the support vector machine (SVM) classifier. The results help us to further understand the mechanism of different aging skin from texture feature and help us to distinguish the different aging states.

Evaluation of age-related changes with cross-sectional CT imaging of teeth

NASA Astrophysics Data System (ADS)

Fukui, Tatsumasa; Kita, Kanade; Kamemoto, Hiromasa; Nishiyama, Wataru; Yoshida, Hiroyasu; Iida, Yukihiro; Katsumata, Akitoshi; Muramatsu, Chisako; Fujita, Hiroshi

2017-03-01

Tooth pulp atrophy occurs with increasing age. An age estimation procedure using dental cone beam computed tomography (CBCT) imaging was developed. Clinical dental CBCT images of 60 patients (aged from 20 to 80 years) were evaluated. The ratio of the cross-sectional area of the pulp cavity to the cross-sectional area of the tooth (pulp cavity ratio) was calculated. The pulp cavity ratio in the labio-lingual plane of the mandibular anterior teeth and the mesio-distal plane of the maxillary anterior teeth was strongly correlated with the patients' age. The pulp cavity ratio of anterior teeth may be a useful parameter for estimating age.

The Development of Experimentation and Evidence Evaluation Skills at Preschool Age

NASA Astrophysics Data System (ADS)

Piekny, Jeanette; Grube, Dietmar; Maehler, Claudia

2014-01-01

Researchers taking a domain-general approach to the development of scientific reasoning long thought that the ability to engage in scientific reasoning did not develop until adolescence. However, more recent studies have shown that preschool children already have a basic ability to evaluate evidence and a basic understanding of experimentation. Data providing insights into when exactly in the preschool years significant gains in these abilities occur are scarce. Drawing on a sample of 138 preschool children, this longitudinal study therefore examined how children's ability to evaluate evidence and their understanding of experimentation develop between the ages of four and six. Findings showed that the ability to evaluate evidence was already well developed at age four and increased steadily and significantly over time as long as the pattern of covariation was perfect. In the case of imperfect covariation, the proportion of correct answers was low over the period of observation, but showed a significant increase between the ages of four and five. If the data did not allow relationship between variables to be inferred, the proportion of correct answers was low, with a significant increase between the ages of five and six. The children's understanding of experimentation increased significantly between the ages of five and six. The implications of these findings for age-appropriate science programs in preschool are discussed.

Improving Evaluation in the Nonprofit Sector: The Promise of Evaluation Capacity Building for Nonprofit Social Service Organizations in an Age of Accountability

ERIC Educational Resources Information Center

Pejsa, Laura J.

2011-01-01

The purpose of this study was to explore the real-world practice of evaluation capacity building (ECB) in the small-medium sized nonprofit context. The study aimed to map the activities, processes, and outcomes of ECB in these nonprofits in light of the competing external and internal evaluation contexts facing nonprofits in an age of…

The Effects of Aging on Clinical Vestibular Evaluations

PubMed Central

Maheu, Maxime; Houde, Marie-Soleil; Landry, Simon P.; Champoux, François

2015-01-01

Balance disorders are common issues for aging populations due to the effects of normal aging on peripheral vestibular structures. These changes affect the results of vestibular function evaluations and make the interpretation of these results more difficult. The objective of this article is to review the current state of knowledge of clinically relevant vestibular measures. We will first focus on otolith function assessment methods cervical-VEMP (cVEMP) and ocular-VEMP (oVEMP), then the caloric and video-head impulse test (vHIT) methods for semicircular canals assessment. cVEMP and oVEMP are useful methods, though research on the effects of age for some parameters are still inconclusive. vHIT results are largely independent of age as compared to caloric stimulation and should therefore be preferred for the evaluation of the semicircular canals function. PMID:26441824

Development of Joint Engagement in Young Deaf and Hearing Children: Effects of Chronological Age and Language Skills

ERIC Educational Resources Information Center

Cejas, Ivette; Barker, David H.; Quittner, Alexandra L.; Niparko, John K.

2014-01-01

Purpose: To evaluate joint engagement (JE) in age-matched children with and without hearing and its relationship to oral language skills. Method: Participants were 180 children with severe-to-profound hearing loss prior to cochlear implant surgery, and 96 age-matched children with normal hearing; all parents were hearing. JE was evaluated in a…

Genetic evaluation and selection response for growth in meat-type quail through random regression models using B-spline functions and Legendre polynomials.

PubMed

Mota, L F M; Martins, P G M A; Littiere, T O; Abreu, L R A; Silva, M A; Bonafé, C M

2018-04-01

The objective was to estimate (co)variance functions using random regression models (RRM) with Legendre polynomials, B-spline function and multi-trait models aimed at evaluating genetic parameters of growth traits in meat-type quail. A database containing the complete pedigree information of 7000 meat-type quail was utilized. The models included the fixed effects of contemporary group and generation. Direct additive genetic and permanent environmental effects, considered as random, were modeled using B-spline functions considering quadratic and cubic polynomials for each individual segment, and Legendre polynomials for age. Residual variances were grouped in four age classes. Direct additive genetic and permanent environmental effects were modeled using 2 to 4 segments and were modeled by Legendre polynomial with orders of fit ranging from 2 to 4. The model with quadratic B-spline adjustment, using four segments for direct additive genetic and permanent environmental effects, was the most appropriate and parsimonious to describe the covariance structure of the data. The RRM using Legendre polynomials presented an underestimation of the residual variance. Lesser heritability estimates were observed for multi-trait models in comparison with RRM for the evaluated ages. In general, the genetic correlations between measures of BW from hatching to 35 days of age decreased as the range between the evaluated ages increased. Genetic trend for BW was positive and significant along the selection generations. The genetic response to selection for BW in the evaluated ages presented greater values for RRM compared with multi-trait models. In summary, RRM using B-spline functions with four residual variance classes and segments were the best fit for genetic evaluation of growth traits in meat-type quail. In conclusion, RRM should be considered in genetic evaluation of breeding programs.

Use of cervical vertebral dimensions for assessment of children growth.

PubMed

Caldas, Maria de Paula; Ambrosano, Gláucia Maria Bovi; Haiter-Neto, Francisco

2007-04-01

The purpose of this study was to investigate whether skeletal maturation using cephalometric radiographs could be used in a Brazilian population. The study population was selected from the files of the Oral Radiological Clinic of the Dental School of Piracicaba, Brazil and consisted of 128 girls and 110 boys (7.0 to 15.9 years old) who had cephalometric and hand-wrist radiographs taken on the same day. Cervical vertebral bone age was evaluated using the method described by Mito and colleagues in 2002. Bone age was assessed by the Tanner-Whitehouse (TW3) method and was used as a gold standard to determine the reliability of cervical vertebral bone age. An analysis of variance and Tukey's post-hoc test were used to compare cervical vertebral bone age, bone age and chronological age at 5% significance level. The analysis of the Brazilian female children data showed that there was a statistically significant difference (p<0.05) between cervical vertebral bone age and chronological age and between bone age and chronological age. However no statistically significant difference (p>0.05) was found between cervical vertebral bone age and bone age. Differently, the analysis of the male children data revealed a statistically significant difference (p<0.05) between cervical vertebral bone age and bone age and between cervical vertebral bone age and chronological age (p<0.05). The findings of the present study suggest that the method for objectively evaluating skeletal maturation on cephalometric radiographs by determination of vertebral bone age can be applied to Brazilian females only. The development of a new method to objectively evaluate cervical vertebral bone age in males is needed.

Inner-Ages of Middle-Aged Prime-Lifers.

ERIC Educational Resources Information Center

Barak, Benny

1998-01-01

Examines three age-role self-concepts: cognitive, ideal, and social with 40-69 year olds who consider themselves middle-aged. Reviews inner-age research and evaluates inner-age infrastructure as well as connections between inner-age and participants' characteristics in the context of eight psychographic trait sets. (Author/MKA)

Cognitive behavior and sensory function were significantly influenced by restoration of active ovarian function in postreproductive mice.

PubMed

Parkinson, Kate C; Peterson, Rhett L; Mason, Jeffrey B

2017-06-01

In mammals, the relationship between reproductive function and health has been particularly difficult to define. Previously, in old, postreproductive-aged mice, replacement of senescent ovaries with new ovaries from young, actively cycling mice increased life span. We hypothesized that the same factors that increased life span would also influence health span. In the current experiments, we tested two of the seven domains of function/health, sensory function and cognition to determine if exposure of postreproductive female mice to young transplanted ovaries influenced health span. We evaluated control female CBA/J mice at six, 13 and 16months of age. Additional mice received new (60d) ovaries at 12 or 17months of age and were subsequently evaluated at 16 or 25months of age, respectively. Evaluation of sensory function included two measures of olfactory perception; olfactory identification (buried pellet test) and olfactory discrimination (novel recognition block test). We found a significant age-related decline in olfactory identification in 16-month old mice. This decline was avoided by ovarian transplantation at 12months of age. The olfactory discrimination block test revealed an age-associated increase in time spent on both the novel and familiar blocks. This trend was reversed in 16-month old new-ovary recipients. We evaluated cognitive behavior with a burrowing behavior test. We detected a significant age-related decrease in burrowing behavior at 16months of age. This age-related decrease in burrowing behavior was prevented by ovarian transplantation at 12months of age. In summary, we have shown that cognitive behavior and sensory function, which are negatively influenced by aging, can be positively influenced or restored by re-establishment of active ovarian function in aged female mice. These findings provide strong incentive for further investigation of the positive influence of young ovaries on restoration of health in postreproductive females. Copyright © 2017 Elsevier Inc. All rights reserved.

Computer-assisted analysis of cervical vertebral bone age using cephalometric radiographs in Brazilian subjects.

PubMed

Caldas, Maria de Paula; Ambrosano, Gláucia Maria Bovi; Haiter Neto, Francisco

2010-01-01

The aims of this study were to develop a computerized program for objectively evaluating skeletal maturation on cephalometric radiographs, and to apply the new method to Brazilian subjects. The samples were taken from the patient files of Oral Radiological Clinics from the North, Northeast, Midwest and South regions of the country. A total of 717 subjects aged 7.0 to 15.9 years who had lateral cephalometric radiographs and hand-wrist radiographs were selected. A cervical vertebral computerized analysis was created in the Radiocef Studio 2 computer software for digital cephalometric analysis, and cervical vertebral bone age was calculated using the formulas developed by Caldas et al.17 (2007). Hand-wrist bone age was evaluated by the TW3 method. Analysis of variance (ANOVA) and the Tukey test were used to compare cervical vertebral bone age, hand-wrist bone age and chronological age (P < 0.05). No significant difference was found between cervical vertebral bone age and chronological age in all regions studied. When analyzing bone age, it was possible to observe a statistically significant difference between cervical vertebral bone age and hand-wrist bone age for female and male subjects in the North and Northeast regions, as well as for male subjects in the Midwest region. No significant difference was observed between bone age and chronological age in all regions except for male subjects in the North and female subjects in the Northeast. Using cervical vertebral bone age, it might be possible to evaluate skeletal maturation in an objective manner using cephalometric radiographs.

[GLIATILIN CORRECTION OF WORKING AND REFERENCE SPATIAL MEMORY IMPAIRMENT IN AGED RATS].

PubMed

Tyurenkov, I N; Volotova, E V; Kurkin, D V

2015-01-01

This work was aimed at evaluating the influence of gliatilin administration on the spatial memory in aged rats. Cognitive function and spatial memory in animals was evaluated using radial (8-beam) maze test. Errors of working spatial memory and reference memory were used as indicators of impaired cognitive function. It was found that aged (24-month) rats compared with younger (6-months) age group exhibited cognitive impairment, as manifested by deterioration of short- and long-term memory processes. Course administration of gliatilin in rats of the older age group at a dose of 100 mg/kg resulted in significant improvement of the working and reference spatial memory in aged rats.

Assessing Defense Structure in School-Age Children Using the Response Evaluation Measure-71-Youth Version (REM-Y-71)

ERIC Educational Resources Information Center

Araujo, Katy B.; Medic, Sanja; Yasnovsky, Jessica; Steiner, Hans

2006-01-01

This study used the Response Evaluation Measure-Youth (REM-Y-71), a self-report measure of 21 defense reactions, among school-age children. Participants were elementary and middle school students (n=290; grades 3-8; age range: 8-15; mean=11.73). Factor analysis revealed a 2-factor defense structure consistent with structure among high school and…

School Age Child Care: Common Issues in Program Design and Evaluation with Annotated Bibliography. Australian Early Childhood Resource Booklets No. 2.

ERIC Educational Resources Information Center

Piscitelli, Barbara

Noting an increase in demand for school-age child care offerings, with no corresponding establishment of guidelines for program development, this booklet addresses design and evaluation issues in school age child care (SACC) in Australia. The booklet is largely based on two surveys of SACC programs conducted in 1986. The issues discussed in the…

An Evaluation of Graduates of a Toddlerhood Home Visiting Program at Kindergarten Age

ERIC Educational Resources Information Center

Allen, LaRue; Sethi, Anita; Astuto, Jennifer

2007-01-01

Overview: A recent evaluation of children who had participated in the Parent-Child Home Program (PCHP) as toddlers found that at kindergarten age, these children were performing at levels expected for their age, despite the fact that they had multiple factors putting them at risk for school failure. The Study: In the winter and spring of 2002, 135…

Evaluation of third molar development in the estimation of chronological age.

PubMed

Soares, Caio Belém Rodrigues Barros; Figueiroa, José Natal; Dantas, Renata Moura Xavier; Kurita, Lúcio Mitsuo; Pontual, Andréa dos Anjos; Ramos-Perez, Flávia Maria de Moraes; Perez, Danyel Elias da Cruz; Pontual, Maria Luiza dos Anjos

2015-09-01

The purpose of this study was to evaluate the correlation between chronological age and the degree of third molar mineralization by Demirjian's developmental stages (Demirjian et al., 1973) using panoramic radiography. From a total of 11.396 digital panoramic radiographs of patients from three oral radiology private clinics from the northeast region of Brazil, obtained from January to June 2009, 2097 radiographic images from patients aged between 6 and 22 years were selected. The images were analyzed individually by two obsevers using a 21-inch computer screen and Windows Picture and Fax Viewer. Reliability was achieved by intra- and interobserver evaluation, using the Kappa test. Chronological age, calcification stage, gender and third molar were interrelated using a multiple linear regression model, considering age as a response variable. There was reliability with Demirjian et al.'s developmental stage assesment, displaying a significant relationship between mineralization stages and patients' age (P<0.05). There was no significant difference between the average age and the calcification stage taking gender and localization of the third molar into consideration. It is possible to estimate chronological age based on Demirjian's stage of a third molar, regardless of gender and location. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Smile esthetics: age related changes, and objective differences between social and spontaneous smiles.

PubMed

Dindaroğlu, Furkan; Doğan, Servet; Erdinç, Ashhan M Ertan

2011-01-01

To evaluate the importance of age in orthodontic treatment by studying the dependence of smile and resting parameters on age and to expose differences between social and spontaneous smiles. Subjects consisted of 67 individuals aged between 17 and 55. The video recordings were transferred to a computer 200 still frames were captured for each individual 50 were captured in resting position, 50 during speech, 50for social, and 50for spontaneous smiles. One picture was selectedfrom each group based on how pictures reflected the desired point ANOVA and Scheffe Post-hoc tests were performed on smile measurements. In all the resting parameters, statistically significant differences were observed among age groups. Also, the response of these parameters to age differs between men and women. Statistically significant diferences were found in some smile parameters among diferent age groups, for both smile types. We find significant differences between social and spontaneous smiles. Age related alterations should be taken into consideration during treatment planning, especially in women. Due to its high consistency, there are advantages with using a spontaneous smile in soft-hard tissue evaluations. We also emphasize the necessity to take dynamic registrations for a true functional evaluation.

[Evaluation of nutritional status of school-age children after implementation of "Nutrition Improvement Program" in rural area in Hunan, China].

PubMed

Deng, Zhu-Juan; Mao, Guang-Xu; Wang, Yu-Jun; Liu, Li; Chen, Yan

2016-09-01

To investigate the nutritional status of school-age children in rural area in Hunan, China from 2012 to 2015 and to evaluate the effectiveness of the "Nutrition Improvement Program for Compulsory Education Students in Rural Area" (hereinafter referred to as "Nutrition Improvement Program"). The nutritional status of school-age children aged 6-14 years was evaluated after the implementation of the "Nutrition Improvement Program" and the changing trend of the children's nutritional status was analyzed. The statistical analysis was performed on the monitoring data of the school-age children aged 6-14 years in rural area in Hunan, China from 2012 to 2015, which came from "The Nutrition and Health Status Monitoring and Evaluation System of Nutrition Improvement Program for Compulsory Education Students in Rural Area". In 2015, female students aged 6-7 years in rural area in Hunan, China had a significantly greater body length than the rural average in China (P<0.05). However, the other age groups had significantly smaller body length and weight than the rural averages in China (P<0.05). After the implementation of "Nutrition Improvement Program", the prevalence rate of growth retardation decreased (P<0.05), but the prevalence rate of emaciation increased (P<0.05). At the same time, the prevalence rate of overweight/obesity increased (P<0.05) and the prevalence rate of anemia decreased (P<0.05). The implementation of "Nutrition Improvement Program" has achieved some success, but the nutritional status of school-age children has not improved significantly. Overweight/obesity and malnutrition are still present. Therefore, to promote the nutritional status of school-age children it is recommended to improve the measures for the "Nutrition Improvement Program".

Children's Moral Evaluations of Reporting the Transgressions of Peers: Age Differences in Evaluations of Tattling

ERIC Educational Resources Information Center

Loke, Ivy Chiu; Heyman, Gail D.; Forgie, Julia; McCarthy, Anjanie; Lee, Kang

2011-01-01

The way children evaluate the reporting of peers' transgressions to authority figures was investigated. Participants, ages 6-11 years (N = 60), were presented with a series of vignettes, each of which depicted a child who committed either a minor transgression (such as not finishing the vegetables at lunch) or a more serious transgression (such as…

Forensic medicine evaluation of Alzheimer patients: a series from Ankara, Turkey.

PubMed

Cavlak, Mehmet; Akçan, Ramazan; Tümer, Ali Riza; Balseven Odabaşi, Aysun; Lale, Aykut; Yildirim, Mahmut Serif; Heybet, Eyüp Ruşen

2015-01-01

Pathophysiological changes due to Alzheimer disease and increasing age might result in situations requiring forensic evaluation in the elderly. Judicial bodies might need forensic evaluation of trauma and the decision-making capacity of Alzheimer patients. This study aimed to determine the demographic and clinical characteristics of Alzheimer patients seen for forensic evaluation. Forensic records issued by the Department of Forensic Medicine of Hacettepe University in 2012 and 2013 were investigated. Patients with Alzheimer disease were included in the study and were analyzed in terms of age, sex, reason for application, comorbid medical conditions, occupation, and place and status of living. There were 30 Alzheimer patients examined in the study period. Of these, 17 (56.6%) were male and 13 (43.3%) were female. The patients' ages ranged between 51 and 90 years, and the mean age was 78.7 years. The majority of cases (25, 83.3%) were transferred for evaluation of decision-making capacity, while only 5 (17.7%) were referred to our department for forensic reporting of bodily damage. Forensic reporting of bodily damage in Alzheimer patients is similar to common injury cases. However, in conditions requiring evaluation of decision-making capacity in Alzheimer patients, all records should be carefully examined and a complete neuropsychiatric evaluation should be performed.

Age at menopause: imputing age at menopause for women with a hysterectomy with application to risk of postmenopausal breast cancer

PubMed Central

Rosner, Bernard; Colditz, Graham A.

2011-01-01

Purpose Age at menopause, a major marker in the reproductive life, may bias results for evaluation of breast cancer risk after menopause. Methods We follow 38,948 premenopausal women in 1980 and identify 2,586 who reported hysterectomy without bilateral oophorectomy, and 31,626 who reported natural menopause during 22 years of follow-up. We evaluate risk factors for natural menopause, impute age at natural menopause for women reporting hysterectomy without bilateral oophorectomy and estimate the hazard of reaching natural menopause in the next 2 years. We apply this imputed age at menopause to both increase sample size and to evaluate the relation between postmenopausal exposures and risk of breast cancer. Results Age, cigarette smoking, age at menarche, pregnancy history, body mass index, history of benign breast disease, and history of breast cancer were each significantly related to age at natural menopause; duration of oral contraceptive use and family history of breast cancer were not. The imputation increased sample size substantially and although some risk factors after menopause were weaker in the expanded model (height, and alcohol use), use of hormone therapy is less biased. Conclusions Imputing age at menopause increases sample size, broadens generalizability making it applicable to women with hysterectomy, and reduces bias. PMID:21441037

Use of Nerve Conduction Velocity to Assess Peripheral Nerve Health in Aging Mice

PubMed Central

Walsh, Michael E.; Sloane, Lauren B.; Fischer, Kathleen E.; Austad, Steven N.; Richardson, Arlan

2015-01-01

Nerve conduction velocity (NCV), the speed at which electrical signals propagate along peripheral nerves, is used in the clinic to evaluate nerve function in humans. A decline in peripheral nerve function is associated with a number of age-related pathologies. While several studies have shown that NCV declines with age in humans, there is little information on the effect of age on NCV in peripheral nerves in mice. In this study, we evaluated NCV in male and female C57Bl/6 mice ranging from 4 to 32 months of age. We observed a decline in NCV in both male and female mice after 20 months of age. Sex differences were detected in sensory NCV as well as the rate of decline during aging in motor nerves; female mice had slower sensory NCV and a slower age-related decline in motor nerves compared with male mice. We also tested the effect of dietary restriction on NCV in 30-month-old female mice. Dietary restriction prevented the age-related decline in sciatic NCV but not other nerves. Because NCV is clinically relevant to the assessment of nerve function, we recommend that NCV be used to evaluate healthspan in assessing genetic and pharmacological interventions that increase the life span of mice. PMID:25477428

Interaction between age of irradiation and age of testing in the disruption of operant performance using a ground-based model for exposure to cosmic rays.

PubMed

Rabin, Bernard M; Joseph, James A; Shukitt-Hale, Barbara; Carrihill-Knoll, Kirsty L

2012-02-01

Previous research has shown a progressive deterioration in cognitive performance in rats exposed to (56)Fe particles as a function of age. The present experiment was designed to evaluate the effects of age of irradiation independently of the age of testing. Male Fischer-344 rats, 2, 7, 12, and 16 months of age, were exposed to 25-200 cGy of (56)Fe particles (1,000 MeV/n). Following irradiation, the rats were trained to make an operant response on an ascending fixed-ratio reinforcement schedule. When performance was evaluated as a function of both age of irradiation and testing, the results showed a significant effect of age on the dose needed to produce a performance decrement, such that older rats exposed to lower doses of (56)Fe particles showed a performance decrement compared to younger rats. When performance was evaluated as a function of age of irradiation with the age of testing held constant, the results indicated that age of irradiation was a significant factor influencing operant responding, such that older rats tested at similar ages and exposed to similar doses of (56)Fe particles showed similar performance decrements. The results are interpreted as indicating that the performance decrement is not a function of age per se, but instead is dependent upon an interaction between the age of irradiation, the age of testing, and exposure to HZE particles. The nature of these effects and how age of irradiation affects cognitive performance after an interval of 15 to 16 months remains to be established.

Evaluation of new binders using newly developed fracture energy test.

DOT National Transportation Integrated Search

2013-07-01

This study evaluated a total of seven asphalt binders with various additives : using the newly developed binder fracture energy test. The researchers prepared and : tested PAV-aged and RTFO-plus-PAV-aged specimens. This study confirmed previous : res...

[Evaluation of the Cystic Eccinococcosis Cases Diagnosed in Dr. Lütfi Kırdar Kartal Education and Research Hospital Pathology Laboratory Between 2007 and 2013].

PubMed

Selek, Ayşegül; Selek, Mehmet Burak; Karadayı, Nimet

2015-06-01

The aim of the study was a retrospective evaluation of 299 cases that were histopathologically diagnosed as cystic echinococcosis (CE) in the pathology laboratory of our hospital in a seven years period. All specimens sent to the laboratory were examined microscopically following macroscopic and hematoxylin eosin (H-E) staining. 299 cases were reviewed according to age, gender and organ affected by the cyst, more than one specimen of the same organ was evaluated once. Of the 299 cases, 44.5% (133) were male whereas 55.5% (166) of them were female. Additionally, %5 (15) of the cases were between 0-15 ages, %31.8 (95) of them were between 16-30 ages, %29.4 (88) of them were between 31-45 ages, % 24.4 (73) of them were between 46-60 ages and %9.4 (28) of them were older than 61. Cysts were mostly localized in liver, lungs and peritoneal cavity, %71.9 (215), %11.4 (34) and %4.7 (14) respectively. Demographic features of our cases were mostly in line with the previous literature. Because of the presence of atypical localized cases, during pathologic evaluation of all surgical cystic specimens, elements of this parasite should be searched and evaluated carefully.

Age-Related Differences in Contribution of Rule-Based Thinking toward Moral Evaluations.

PubMed

Caravita, Simona C S; De Silva, Lindamulage N; Pagani, Vera; Colombo, Barbara; Antonietti, Alessandro

2017-01-01

This study aims to investigate the interplay of different criteria of moral evaluation, related to the type of the rule and context characteristics, in moral reasoning of children, early, and late adolescents. Students attending to fourth, seventh, and tenth grade were asked to evaluate the acceptability of rule breaking actions using ad hoc scenarios. Results suggest that the role of different moral evaluation criteria changes by age. During adolescence a greater integration of the moral criteria emerged. Moreover, adolescents also prioritized the evaluation of moral rule (forbidding to harm others) violations as non-acceptable when the perpetrator harms an innocent victim by applying a direct personal force. The relevance of these findings to increase the understanding of how moral reasoning changes by age for the assessment of impairments in moral reasoning of non-normative groups is also discussed.

Female age-related fertility decline. Committee Opinion No. 589.

PubMed

2014-03-01

The fecundity of women decreases gradually but significantly beginning approximately at age 32 years and decreases more rapidly after age 37 years. Education and enhanced awareness of the effect of age on fertility are essential in counseling the patient who desires pregnancy. Given the anticipated age-related decline in fertility, the increased incidence of disorders that impair fertility, and the higher risk of pregnancy loss, women older than 35 years should receive an expedited evaluation and undergo treatment after 6 months of failed attempts to conceive or earlier, if clinically indicated. In women older than 40 years, more immediate evaluation and treatment are warranted.

75 FR 4829 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-29

... Institute on Aging Special Emphasis Panel; Summer Research Training In Aging For Medical Students--NIA T35... review and evaluate contract proposals. Place: National Institute on Aging, Gateway Building, 7201..., Aging Research, National Institutes of Health, HHS) [[Page 4830

Evaluation of Cervicography Screening for Cervical Cancer in a High Risk Population

DTIC Science & Technology

2000-02-16

Higher sensitivity was associated with younger age , premenopausal status, the presence of metaplasia. the absence of cervicovaginal atrophy, and improved...recommended for postmenopausal women and/or women ages 50 and older. iv EVALUATION OF CERVICOGRAPHY SCREENING FOR CERVICAL CANCER IN A HIGH-RISK POPULATION...Institute. The Guanacaste site was selected because of its consistently high age -adjusted rates of cervical cancer despite existing Papanicolaou

Characterization of facial skin of various Asian populations through visual and non-invasive instrumental evaluations: influence of age and skincare habits.

PubMed

Galzote, Carlos; Estanislao, Roderico; Suero, Michael Oliver; Khaiat, Alain; Mangubat, Maria Isabel; Moideen, Rafeeq; Tagami, Hachiro; Wang, Xuemin

2013-11-01

We aimed to evaluate the impact of age and skincare habits on facial skin of different Asian ethnicities by comparing skin properties and skincare habits among various Asian populations of varying age groups. We evaluated approximately 100 female subjects each from a total of eight Asian cities in China, India, South Korea, Japan, and the Philippines grouped according to age ranging from 14 to 75 years during a summer season. Facial skin was characterized using dermatological examinations of the cheek and instrumental evaluations of the forehead and cheek. Information regarding personal skincare habits was collected using a questionnaire. In 834 female subjects, characteristics related to skin surface moisture, elasticity, and sebum level decreased with age. Differences in skincare habits corresponded with variations in skin parameters. Subjects with the least severe photodamage reported a generally early onset of their skincare habits. These results demonstrate common trends as well as inherent differences in skin characteristics among Asian populations, reflecting the impact of age and the diversity of skincare habits of Asian women. These results may be beneficial when developing new skincare products that are well suited to these Asian populations. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Content fat and calorie of human milk is affected by interactions between maternal age and body mass index.

PubMed

Hahn, Won-Ho; Jeong, Tchaewon; Park, Suyeon; Song, Seunghyun; Kang, Nam Mi

2018-05-01

We evaluated the association between macronutrients of human milk (HM), and interactions between maternal age and body mass index(BMI) in matched conditions. Totally, 80 HM samples were collected from healthy breast-feeding mothers at fourth week of lactation. HM macronutrients and maternal data were analyzed. Mothers were subgrouped into four groups by maternal age (20 s/30 s) and BMI (overweight/normal). Two-way ANOVA revealed significant interactions between age and BMI to affect macronutrients; fat, carbohydrate, and calories. Moreover, different responses of fat and calorie to BMI were found in different age groups. The evaluation of over- or under-weighted infants warrants considering both of maternal age and BMI.

The Preventative Effects of a Brief, Early Intervention for Preschool-Aged Children at Risk for Internalising: Follow-up into Middle Adolescence

ERIC Educational Resources Information Center

Rapee, Ronald M.

2013-01-01

Background: There are few evaluations of very early intervention for the prevention of internalising disorders and those that exist generally evaluate outcomes to a maximum of 12 months. The current study evaluated the very long term effects (11 years) of a brief internalising prevention program presented to parents of preschool aged children.…

How Japanese adults perceive memory change with age: middle-aged adults with memory performance as high as young adults evaluate their memory abilities as low as older adults.

PubMed

Kinjo, Hikari; Shimizu, Hiroyuki

2014-01-01

The characteristics of self-referent beliefs about memory change with age. The relationship between beliefs and memory performance of three age groups of Japanese adults was investigated. The beliefs measured by the Personal Beliefs about Memory Instrument (Lineweaver & Hertzog, 1998) differed among the age groups and between sexes. In most scales, the ratings by middle-aged adults were as low as those by older adults, which were lower than those by young adults. Women perceived their memory abilities as lower than men's, with no interaction between age and sex, suggesting the difference remains across the lifespan. For middle-aged adults, the better they performed in cued-recall, free recall, and recognition, the lower they evaluated their memory self-efficacy, while few relationships were found for other groups. Our results suggest that cognitive beliefs change with age and that investigating the beliefs of the middle-aged adults is indispensable to elucidate the transition of beliefs.

Assessment of three risk evaluation systems for patients aged ≥70 in East China: performance of SinoSCORE, EuroSCORE II and the STS risk evaluation system.

PubMed

Shan, Lingtong; Ge, Wen; Pu, Yiwei; Cheng, Hong; Cang, Zhengqiang; Zhang, Xing; Li, Qifan; Xu, Anyang; Wang, Qi; Gu, Chang; Zhang, Yangyang

2018-01-01

To assess and compare the predictive ability of three risk evaluation systems (SinoSCORE, EuroSCORE II and the STS risk evaluation system) in patients aged ≥70, and who underwent coronary artery bypass grafting (CABG) in East China. Three risk evaluation systems were applied to 1,946 consecutive patients who underwent isolated CABG from January 2004 to September 2016 in two hospitals. Patients were divided into two subsets according to their age: elderly group (age ≥70) with a younger group (age <70) used for comparison. The outcome of interest in this study was in-hospital mortality. The entire cohort and subsets of patients were analyzed. The calibration and discrimination in total and in subsets were assessed by the Hosmer-Lemeshow and the C statistics respectively. Institutional overall mortality was 2.52%. The expected mortality rates of SinoSCORE, EuroSCORE II and the STS risk evaluation system were 0.78(0.64)%, 1.43(1.14)% and 0.78(0.77)%, respectively. SinoSCORE achieved the best discrimination (the area under the receiver operating characteristic curve (AUC) = 0.829), followed by the STS risk evaluation system (AUC = 0.790) and EuroSCORE II (AUC = 0.769) in the entire cohort. In the elderly group, the observed mortality rate was 4.82% while it was 1.38% in the younger group. SinoSCORE (AUC = .829) also achieved the best discrimination in the elderly group, followed by the STS risk evaluation system (AUC = .730) and EuroSCORE II (AUC = 0.640) while all three risk evaluation systems all had good performances in the younger group. SinoSCORE, EuroSCORE II and the STS risk evaluation system all achieved positive calibrations in the entire cohort and subsets. The performance of the three risk evaluation systems was not ideal in the entire cohort. In the elderly group, SinoSCORE appeared to achieve better predictive efficiency than EuroSCORE II and the STS risk evaluation system.

Age-Related Differences in Contribution of Rule-Based Thinking toward Moral Evaluations

PubMed Central

Caravita, Simona C. S.; De Silva, Lindamulage N.; Pagani, Vera; Colombo, Barbara; Antonietti, Alessandro

2017-01-01

This study aims to investigate the interplay of different criteria of moral evaluation, related to the type of the rule and context characteristics, in moral reasoning of children, early, and late adolescents. Students attending to fourth, seventh, and tenth grade were asked to evaluate the acceptability of rule breaking actions using ad hoc scenarios. Results suggest that the role of different moral evaluation criteria changes by age. During adolescence a greater integration of the moral criteria emerged. Moreover, adolescents also prioritized the evaluation of moral rule (forbidding to harm others) violations as non-acceptable when the perpetrator harms an innocent victim by applying a direct personal force. The relevance of these findings to increase the understanding of how moral reasoning changes by age for the assessment of impairments in moral reasoning of non-normative groups is also discussed. PMID:28473788

Defecography by digital radiography: experience in clinical practice.

PubMed

Gonçalves, Amanda Nogueira de Sá; Sala, Marco Aurélio Sousa; Bruno, Rodrigo Ciotola; Xavier, José Alberto Cunha; Indiani, João Mauricio Canavezi; Martin, Marcelo Fontalvo; Bruno, Paulo Maurício Chagas; Nacif, Marcelo Souto

2016-01-01

The objective of this study was to profile patients who undergo defecography, by age and gender, as well as to describe the main imaging and diagnostic findings in this population. This was a retrospective, descriptive study of 39 patients, conducted between January 2012 and February 2014. The patients were evaluated in terms of age, gender, and diagnosis. They were stratified by age, and continuous variables are expressed as mean ± standard deviation. All possible quantitative defecography variables were evaluated, including rectal evacuation, perineal descent, and measures of the anal canal. The majority (95%) of the patients were female. Patient ages ranged from 18 to 82 years (mean age, 52 ± 13 years): 10 patients were under 40 years of age; 18 were between 40 and 60 years of age; and 11 were over 60 years of age. All 39 of the patients evaluated had abnormal radiological findings. The most prevalent diagnoses were rectocele (in 77%) and enterocele (in 38%). Less prevalent diagnoses were vaginal prolapse, uterine prolapse, and Meckel's diverticulum (in 2%, for all). Although defecography is performed more often in women, both genders can benefit from the test. Defecography can be performed in order to detect complex disorders such as uterine and rectal prolapse, as well as to detect basic clinical conditions such as rectocele or enterocele.

Folate/Folic Acid Knowledge, Intake, and Self-Efficacy of College-Aged Women: Impact of Text Messaging and Availability of a Folic Acid-Containing Supplement

ERIC Educational Resources Information Center

Rampersaud, Gail C.; Sokolow, Andrew; Gruspe, Abigail; Colee, James C.; Kauwell, Gail P. A.

2016-01-01

Objective: To evaluate the impact of educational text messages (TMs) on folate/folic acid knowledge and consumption among college-aged women, and to evaluate the impact of providing folic acid supplements on folate/folic acid intake among college-aged women. Participants: A total of 162 women (18-24 years) recruited from a university. Methods: The…

Obtaining appropriate interval estimates for age when multiple indicators are used: evaluation of an ad-hoc procedure.

PubMed

Fieuws, Steffen; Willems, Guy; Larsen-Tangmose, Sara; Lynnerup, Niels; Boldsen, Jesper; Thevissen, Patrick

2016-03-01

When an estimate of age is needed, typically multiple indicators are present as found in skeletal or dental information. There exists a vast literature on approaches to estimate age from such multivariate data. Application of Bayes' rule has been proposed to overcome drawbacks of classical regression models but becomes less trivial as soon as the number of indicators increases. Each of the age indicators can lead to a different point estimate ("the most plausible value for age") and a prediction interval ("the range of possible values"). The major challenge in the combination of multiple indicators is not the calculation of a combined point estimate for age but the construction of an appropriate prediction interval. Ignoring the correlation between the age indicators results in intervals being too small. Boldsen et al. (2002) presented an ad-hoc procedure to construct an approximate confidence interval without the need to model the multivariate correlation structure between the indicators. The aim of the present paper is to bring under attention this pragmatic approach and to evaluate its performance in a practical setting. This is all the more needed since recent publications ignore the need for interval estimation. To illustrate and evaluate the method, Köhler et al. (1995) third molar scores are used to estimate the age in a dataset of 3200 male subjects in the juvenile age range.

Integrated Evaluation of Age-Related Changes in Structural and Functional Vascular Parameters Used to Assess Arterial Aging, Subclinical Atherosclerosis, and Cardiovascular Risk in Uruguayan Adults: CUiiDARTE Project

PubMed Central

Bia, Daniel; Zócalo, Yanina; Farro, Ignacio; Torrado, Juan; Farro, Federico; Florio, Lucía; Olascoaga, Alicia; Brum, Javier; Alallón, Walter; Negreira, Carlos; Lluberas, Ricardo; Armentano, Ricardo L.

2011-01-01

This work was carried out in a Uruguayan (South American) population to characterize aging-associated physiological arterial changes. Parameters markers of subclinical atherosclerosis and that associate age-related changes were evaluated in healthy people. A conservative approach was used and people with nonphysiological and pathological conditions were excluded. Then, we excluded subjects with (a) cardiovascular (CV) symptoms, (b) CV disease, (c) diabetes mellitus or renal failure, and (d) traditional CV risk factors (other than age and gender). Subjects (n = 388) were submitted to non-invasive vascular studies (gold-standard techniques), to evaluate (1) common (CCA), internal, and external carotid plaque prevalence, (2) CCA intima-media thickness and diameter, (3) CCA stiffness (percentual pulsatility, compliance, distensibility, and stiffness index), (4) aortic stiffness (carotid-femoral pulse wave velocity), and (5) peripheral and central pressure wave-derived parameters. Age groups: ≤20, 21–30, 31–40, 41–50, 51–60, 61–70, and 71–80 years old. Age-related structural and functional vascular parameters profiles were obtained and analyzed considering data from other populations. The work has the strength of being the first, in Latin America, that uses an integrative approach to characterize vascular aging-related changes. Data could be used to define vascular aging and abnormal or disease-related changes. PMID:22187622

Integrated Evaluation of Age-Related Changes in Structural and Functional Vascular Parameters Used to Assess Arterial Aging, Subclinical Atherosclerosis, and Cardiovascular Risk in Uruguayan Adults: CUiiDARTE Project.

PubMed

Bia, Daniel; Zócalo, Yanina; Farro, Ignacio; Torrado, Juan; Farro, Federico; Florio, Lucía; Olascoaga, Alicia; Brum, Javier; Alallón, Walter; Negreira, Carlos; Lluberas, Ricardo; Armentano, Ricardo L

2011-01-01

This work was carried out in a Uruguayan (South American) population to characterize aging-associated physiological arterial changes. Parameters markers of subclinical atherosclerosis and that associate age-related changes were evaluated in healthy people. A conservative approach was used and people with nonphysiological and pathological conditions were excluded. Then, we excluded subjects with (a) cardiovascular (CV) symptoms, (b) CV disease, (c) diabetes mellitus or renal failure, and (d) traditional CV risk factors (other than age and gender). Subjects (n = 388) were submitted to non-invasive vascular studies (gold-standard techniques), to evaluate (1) common (CCA), internal, and external carotid plaque prevalence, (2) CCA intima-media thickness and diameter, (3) CCA stiffness (percentual pulsatility, compliance, distensibility, and stiffness index), (4) aortic stiffness (carotid-femoral pulse wave velocity), and (5) peripheral and central pressure wave-derived parameters. Age groups: ≤20, 21-30, 31-40, 41-50, 51-60, 61-70, and 71-80 years old. Age-related structural and functional vascular parameters profiles were obtained and analyzed considering data from other populations. The work has the strength of being the first, in Latin America, that uses an integrative approach to characterize vascular aging-related changes. Data could be used to define vascular aging and abnormal or disease-related changes.

Uncertainty in age-specific harvest estimates and consequences for white-tailed deer management

USGS Publications Warehouse

Collier, B.A.; Krementz, D.G.

2007-01-01

Age structure proportions (proportion of harvested individuals within each age class) are commonly used as support for regulatory restrictions and input for deer population models. Such use requires critical evaluation when harvest regulations force hunters to selectively harvest specific age classes, due to impact on the underlying population age structure. We used a stochastic population simulation model to evaluate the impact of using harvest proportions to evaluate changes in population age structure under a selective harvest management program at two scales. Using harvest proportions to parameterize the age-specific harvest segment of the model for the local scale showed that predictions of post-harvest age structure did not vary dependent upon whether selective harvest criteria were in use or not. At the county scale, yearling frequency in the post-harvest population increased, but model predictions indicated that post-harvest population size of 2.5 years old males would decline below levels found before implementation of the antler restriction, reducing the number of individuals recruited into older age classes. Across the range of age-specific harvest rates modeled, our simulation predicted that underestimation of age-specific harvest rates has considerable influence on predictions of post-harvest population age structure. We found that the consequence of uncertainty in harvest rates corresponds to uncertainty in predictions of residual population structure, and this correspondence is proportional to scale. Our simulations also indicate that regardless of use of harvest proportions or harvest rates, at either the local or county scale the modeled SHC had a high probability (>0.60 and >0.75, respectively) of eliminating recruitment into >2.5 years old age classes. Although frequently used to increase population age structure, our modeling indicated that selective harvest criteria can decrease or eliminate the number of white-tailed deer recruited into older age classes. Thus, we suggest that using harvest proportions for management planning and evaluation should be viewed with caution. In addition, we recommend that managers focus more attention on estimation of age-specific harvest rates, and modeling approaches which combine harvest rates with information from harvested individuals to further increase their ability to effectively manage deer populations under selective harvest programs. ?? 2006 Elsevier B.V. All rights reserved.

[Auditory processing evaluation in children born preterm].

PubMed

Gallo, Júlia; Dias, Karin Ziliotto; Pereira, Liliane Desgualdo; Azevedo, Marisa Frasson de; Sousa, Elaine Colombo

2011-01-01

To verify the performance of children born preterm on auditory processing evaluation, and to correlate the data with behavioral hearing assessment carried out at 12 months of age, comparing the results to those of auditory processing evaluation of children born full-term. Participants were 30 children with ages between 4 and 7 years, who were divided into two groups: Group 1 (children born preterm), and Group 2 (children born full-term). The auditory processing results of Group 1 were correlated to data obtained from the behavioral auditory evaluation carried out at 12 months of age. The results were compared between groups. Subjects in Group 1 presented at least one risk indicator for hearing loss at birth. In the behavioral auditory assessment carried out at 12 months of age, 38% of the children in Group 1 were at risk for central auditory processing deficits, and 93.75% presented auditory processing deficits on the evaluation. Significant differences were found between the groups for the temporal order test, the PSI test with ipsilateral competitive message, and the speech-in-noise test. The delay in sound localization ability was associated to temporal processing deficits. Children born preterm have worse performance in auditory processing evaluation than children born full-term. Delay in sound localization at 12 months is associated to deficits on the physiological mechanism of temporal processing in the auditory processing evaluation carried out between 4 and 7 years.

Time-related degradation, a key issue in nuclear plant safety evaluations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonzon, L.L.; Bustard, L.D.; Clough, R.L.

1982-01-01

Sandia National Laboratories is conducting a number of programs under NRC sponsorship which deal with safety-related equipment qualification issues, including the important aspect of aging. Among these is the Qualification Testing Evaluation (QTE) program which was probably the first to devote significant effort towards aging research and was one of the primary motivators leading to the Workshop. The thrust of the QTE aging efforts has been on elastomeric materials, typically used in electrical cables, seals, gaskets, and the like; currently, efforts are being pursued on plant ambient environments measurements, aging of electronics, and aging of motors. A brief status reportmore » is presented in this paper.« less

Evaluation of the Specialized, Volunteer Transportation Program of the Area IV Agency on Aging and Community Service

DOT National Transportation Integrated Search

1987-08-01

This report contains an evaluation of a specialized volunteer, rural : transportation program implemented in April of 1986. The Area IV Agency on : Aging and Community Services received a grant from the Urban Mass Transit : Administration for this pr...

75 FR 70949 - Proposed Information Collection for the Evaluation of the Aging Worker Initiative; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-19

... OMB-approved quarterly and Common Measures reporting requirements for High Growth Job Training Grants... DEPARTMENT OF LABOR Employment and Training Administration Proposed Information Collection for the Evaluation of the Aging Worker Initiative; Comment Request AGENCY: Employment and Training Administration...

The Etiology of Mathematical Self-Evaluation and Mathematics Achievement: Understanding the Relationship Using a Cross-Lagged Twin Study from Ages 9 to 12

ERIC Educational Resources Information Center

Luo, Yu L. L.; Kovas, Yulia; Haworth, Claire M. A.; Plomin, Robert

2011-01-01

The genetic and environmental origins of individual differences in mathematical self-evaluation over time and its association with later mathematics achievement were investigated in a UK sample of 2138 twin pairs at ages 9 and 12. Self-evaluation indexed how good children think they are at mathematical activities and how much they like those…

Reliability and validity of a quantitative color scale to evaluate masticatory performance using color-changeable chewing gum.

PubMed

Hama, Yohei; Kanazawa, Manabu; Minakuchi, Shunsuke; Uchida, Tatsuro; Sasaki, Yoshiyuki

2014-03-19

In the present study, we developed a novel color scale for visual assessment, conforming to theoretical color changes of a gum, to evaluate masticatoryperformance; moreover, we investigated the reliability and validity of this evaluation method using the color scale. Ten participants (aged 26.30 years) with natural dentition chewed the gum at several chewing strokes. Changes in color were measured using a colorimeter, and then, linearregression expressions that represented changes in gum color were derived. The color scale was developed using these regression expressions. Thirty-two chewed gums were evaluated using colorimeter and were assessed three times using the color scale by six dentists aged 25.27 (mean, 25.8) years, six preclinical dental students aged 21.23 (mean, 22.2) years, and six elderly individuals aged 68.84 (mean, 74.0) years. The intrarater and interrater reliability of evaluations was assessed using intraclass correlation coefficients. Validity of the method compared with a colorimeter was assessed using Spearman's rank correlation coefficient. All intraclass correlation coefficients were > 0.90, and Spearman's rank-correlation coefficients were > 0.95 in all groups. These results indicated that the evaluation method of the color-changeable chewing gum using the newly developed color scale is reliable and valid.

Disparities in the diagnostic process of Duchenne and Becker muscular dystrophy.

PubMed

Holtzer, Caleb; Meaney, F John; Andrews, Jennifer; Ciafaloni, Emma; Fox, Deborah J; James, Katherine A; Lu, Zhenqiang; Miller, Lisa; Pandya, Shree; Ouyang, Lijing; Cunniff, Christopher

2011-11-01

To determine whether sociodemographic factors are associated with delays at specific steps in the diagnostic process of Duchenne and Becker muscular dystrophy. We examined abstracted medical records for 540 males from population-based surveillance sites in Arizona, Colorado, Georgia, Iowa, and western New York. We used linear regressions to model the association of three sociodemographic characteristics with age at initial medical evaluation, first creatine kinase measurement, and earliest DNA analysis while controlling for changes in the diagnostic process over time. The analytical dataset included 375 males with information on family history of Duchenne and Becker muscular dystrophy, neighborhood poverty levels, and race/ethnicity. Black and Hispanic race/ethnicity predicted older ages at initial evaluation, creatine kinase measurement, and DNA testing (P < 0.05). A positive family history of Duchenne and Becker muscular dystrophy predicted younger ages at initial evaluation, creatine kinase measurement and DNA testing (P < 0.001). Higher neighborhood poverty was associated with earlier ages of evaluation (P < 0.05). Racial and ethnic disparities in the diagnostic process for Duchenne and Becker muscular dystrophy are evident even after adjustment for family history of Duchenne and Becker muscular dystrophy and changes in the diagnostic process over time. Black and Hispanic children are initially evaluated at older ages than white children, and the gap widens at later steps in the diagnostic process.

Evaluation of paraxial forward scattering from intraocular lens with increased surface light scattering using goniophotometry and Hartmann-Shack wavefront aberrometry.

PubMed

Minami, Keiichiro; Maruyama, Yoko; Mihashi, Toshifumi; Miyata, Kazunori; Oshika, Tetsuro

2017-03-01

To evaluate the influence of increases in light scattering on intraocular lens (IOL) surfaces on paraxial forward scattering using goniophotometry and Hartmann-Shack wavefront aberrometry. Surface light scattering was reproduced experimentally by acceleratedly aging 4 intraocular lenses by 0, 3, 5, and 10 years each. Light scattering from both IOL surfaces was measured using Scheimpflug photography. The paraxial forward scattering from the aged IOLs was measured using a goniophotometer with a halogen light source (wavelength: 350-850 nm) and telecentric optics, and changes in the maximum intensity and full width at 10% of maximum intensity (FW10%) were evaluated. The influences on the retina image were examined using a Hartmann-Shack aberrometer (wavelength: 840 nm). The contrast and difference from the point spread function of the central centroids were evaluated. The mean surface light scattering from both IOL surfaces ranged from 30.0 to 118.3 computer compatible tape (CCT) and increased with each aging year. Evaluations using the goniophotometer and the Hartmann-Shack aberrometer showed no significant change in the paraxial forward scattering with the aging year (P > .45, Kruskal-Wallis test), and no association with the surface light scattering intensity was found (P > .75, Spearman rank correlation). This experimental study using aged IOLs demonstrated that surface light scattering does not influence paraxial forward scattering.

Age Differences in Coping with Chronic Illness.

ERIC Educational Resources Information Center

Felton, Barbara J.; Revenson, Tracey A.

While most lifespan developmental theories of personality predict age-related changes in coping, little direct evidence exists for determining whether age differences in coping style are due to intrinsic developmental processes or to age differences in the kinds of stresses encountered. To evaluate age differences in coping strategies and whether…

Effects of Hygrothermal Cycling on the Chemical, Thermal, and Mechanical Properties of 862/W Epoxy Resin

NASA Technical Reports Server (NTRS)

Miller, Sandi G.; Roberts, Gary D.; Copa, Christine C.; Bail, Justin L.; Kohlman, Lee W.; Binienda, Wieslaw K.

2011-01-01

The hygrothermal aging characteristics of an epoxy resin were characterized over 1 year, which included 908 temperature and humidity cycles. The epoxy resin quickly showed evidence of aging through color change and increased brittleness. The influence of aging on the material s glass transition temperature (Tg) was evaluated by Differential Scanning Calorimetry (DSC) and Dynamic Mechanical Analysis (DMA). The Tg remained relatively constant throughout the year long cyclic aging profile. The chemical composition was monitored by Fourier Transform Infrared Spectroscopy (FTIR) where evidence of chemical aging and advancement of cure was noted. The tensile strength of the resin was tested as it aged. This property was severely affected by the aging process in the form of reduced ductility and embrittlement. Detailed chemical evaluation suggests many aging mechanisms are taking place during exposure to hygrothermal conditions. This paper details the influence of processes such as: advancement of cure, chemical degradation, and physical aging on the chemical and physical properties of the epoxy resin.

Evaluating the interdependence of aging-related changes in visual and auditory acuity, balance, and cognitive functioning.

PubMed

Hofer, Scott M; Berg, Stig; Era, Pertti

2003-06-01

High proportions of shared age-related variance are found among measures of perceptual acuity, balance, muscle strength, and cognitive capabilities in age-heterogeneous, cross-sectional studies. Reliance on cross-sectional studies is problematic, however, because associations may arise from age-related mean trends. Narrow age-cohort samples provide an alternative basis for testing hypotheses regarding associations among rates of change. Cross-domain associations were evaluated in combined 75-year-old cohort samples from Denmark, Finland, and Sweden. In general, no consistent associations were found across sensory, balance, strength, and cognitive domains. These findings indicate that the effects of aging on sensory acuity, balance, and cognitive functioning are likely to be largely independent, multidimensional, and complex at the level of the individual.

Disaster resilience and population ageing: the 1995 Kobe and 2004 Chuetsu earthquakes in Japan.

PubMed

Chen, Haili; Maki, Norio; Hayashi, Haruo

2014-04-01

This paper provides a framework for evaluating the effects of population ageing on disaster resilience. In so doing, it focuses on the 1995 Kobe and 2004 Chuetsu earthquakes, two major disasters that affected Japan before the 2011 Great East Japan earthquake. It analyses regional population recovery on the basis of pre-disaster and post-recovery demographic characteristics using defined transition patterns of population ageing. The evaluation framework demonstrates that various recovery measures make different contributions to disaster resilience for each transition pattern of population ageing. With reference to regional population ageing, the framework allows for a prediction of disaster resilience, facilitating place vulnerability assessments and potentially informing policy-making strategies for Japan and other countries with ageing populations. © 2014 The Author(s). Disasters © Overseas Development Institute, 2014.

[Evaluation of the acceptability of a formula for children with diarrhea in a marginal community].

PubMed

Hernández Ramírez, B D; Guerra, M J

1995-01-01

Evaluated the acceptability of a nutrition formula consisting of pumpkin-rice chicken and oils; in a marginal community to children between the ages of 7 months to 5 years old when acute diarrhea was present. The acceptability was also evaluated in the mothers, who indicated that they liked food very little. Nevertheless, they admitted that they would give the product to their children. During the period of study 26 cases of diarrhea were reported of the 26 children, 6 children consumed all the food offered, 16 children showed variable acceptance and only 4 children reject the food completely. By age-groups, the acceptability was 75.69% for children between the ages of 7 months to one year. 72.90% acceptability for ages between 13 months to 2 years and 78.28% for ages between 25 months to 5 years old. The total acceptability was 75.66%. All cases presented marked decreased in diarrhea and an increased in the consistency of the feces with the third dose.

76 FR 65203 - National Institute on Aging

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special Emphasis... and evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin...

Estimation of Gestational Age: Implications for Developmental Research.

ERIC Educational Resources Information Center

DiPietro, Janet A.; Allen, Marilee C.

1991-01-01

Reviews prenatal and postnatal methods of gestational age estimation and evaluates implementation of this information in research. Recommendations concerning the assignment of gestational age in the perinatal period and the use of age correction for preterm infants are offered. (Author/BC)

Professor Age and Gender Affect Student Perceptions and Grades

ERIC Educational Resources Information Center

Joye, Shauna W.; Wilson, Janie H.

2015-01-01

Student evaluations provide rich information about teaching performance, but a number of factors beyond teacher effectiveness influence student evaluations. In this study we examined the effects of professor gender and perceived age on ratings of effectiveness and rapport as well as academic performance. We also asked students to rate professor…

Literacy Achievement in India: A Demographic Evaluation

ERIC Educational Resources Information Center

Shukla, Vachaspati; Mishra, Udaya S.

2017-01-01

This article evaluates the progress in literacy among the Indian states, from an age-cohort perspective. It argues that age-cohort analysis offers a robust understanding of the dynamics of literacy progress. The article clearly brings out the fact that, despite the accomplishment of universal elementary education, achieving the goal of full…

Measuring Future Time Perspective across Adulthood: Development and Evaluation of a Brief Multidimensional Questionnaire

PubMed Central

Brothers, Allyson; Chui, Helena; Diehl, Manfred

2014-01-01

Purpose of the Study: Despite calls for the consideration of future time perspective (FTP) as a multidimensional construct, mostly unidimensional measurement instruments have been used. This study had two objectives: (a) to develop a brief multidimensional questionnaire for assessing FTP in adulthood and evaluate its psychometric properties; and (b) to examine age associations and age-group differences of the dimensions of FTP. Design and Methods: Data were collected from 625 community-residing adults between the ages of 18 and 93, representing young, middle-aged, and older adults. The psychometric evaluation involved exploratory factor analyses (EFA) and confirmatory FA (CFA), reliability and validity analyses, and measurement invariance testing. Zero-order and partial correlations were used to examine the association of the dimensions of FTP with age, and multivariate analysis of variance was used to examine age-group differences. Results: EFA and CFA supported a three-factor solution: Future as Open, Future as Limited, and Future as Ambiguous. Metric measurement invariance for this factor structure was confirmed across the three age groups. Reliability and validity analyses provided evidence of sound psychometric properties of the brief questionnaire. Age was negatively associated with Future as Open and positively associated with Future as Limited. Young adults exhibited significantly greater ambiguity toward the future than middle-aged or older adults. Implications: This study provides evidence in support of the psychometric properties of a new brief multidimensional FTP scale. It also provides evidence for a pattern of age associations and age-group differences consistent with life-span developmental theory. PMID:25063938

Age threshold for moderate and severe periodontitis among Korean adults without diabetes mellitus, hypertension, metabolic syndrome, and/or obesity.

PubMed

Han, Kyungdo; Park, Jun-Beom

2017-08-01

The purpose of this study is to determine an appropriate age threshold at which to recommend the evaluation of moderate and severe periodontitis among Korean adults.This study involved a cross-sectional analysis using data from the Korean National Health and Nutrition Examination Survey from 2012 to 2014. Incidence rates of periodontitis with the 95% confidence interval (CI) were evaluated. The predictive accuracy of age for periodontitis was determined by calculating the area under curve (AUC) on the basis of the receiver operating characteristic (ROC) curve.The cutoff value of age was 43 years in men having periodontitis with an AUC of 0.70 with 95% CI of 0.69 to 0.72. The AUC was 0.72 (95% CI: 0.70-0.73), and the cutoff value of age (49 years) was identified for the moderate periodontitis in women. The cutoff values for age with AUCs and 95% CI for individuals with periodontitis were 46 years (0.72 [0.71-0.73]), 43 years (0.73 [0.72, 0.74]), 45 years (0.71 [0.70,0.72]), 43 years (0.73 [0.72, 0.74]), and 45 years (0.74 [0.72, 0.75]) for no obesity, no abdominal obesity, no diabetes mellitus, no hypertension, and no metabolic syndrome groups, respectively.This study proposed the guideline for the appropriate age threshold at which to recommend the evaluation of moderate and severe periodontitis for the general population and additionally added the guideline for the individuals without systemic disease including diabetes mellitus, hypertension, metabolic syndrome, and obesity. This study suggests that the participants with certain age may be recommended for the regular periodontal evaluation.

Age threshold for moderate and severe periodontitis among Korean adults without diabetes mellitus, hypertension, metabolic syndrome, and/or obesity

PubMed Central

Han, Kyungdo; Park, Jun-Beom

2017-01-01

Abstract The purpose of this study is to determine an appropriate age threshold at which to recommend the evaluation of moderate and severe periodontitis among Korean adults. This study involved a cross-sectional analysis using data from the Korean National Health and Nutrition Examination Survey from 2012 to 2014. Incidence rates of periodontitis with the 95% confidence interval (CI) were evaluated. The predictive accuracy of age for periodontitis was determined by calculating the area under curve (AUC) on the basis of the receiver operating characteristic (ROC) curve. The cutoff value of age was 43 years in men having periodontitis with an AUC of 0.70 with 95% CI of 0.69 to 0.72. The AUC was 0.72 (95% CI: 0.70–0.73), and the cutoff value of age (49 years) was identified for the moderate periodontitis in women. The cutoff values for age with AUCs and 95% CI for individuals with periodontitis were 46 years (0.72 [0.71–0.73]), 43 years (0.73 [0.72, 0.74]), 45 years (0.71 [0.70,0.72]), 43 years (0.73 [0.72, 0.74]), and 45 years (0.74 [0.72, 0.75]) for no obesity, no abdominal obesity, no diabetes mellitus, no hypertension, and no metabolic syndrome groups, respectively. This study proposed the guideline for the appropriate age threshold at which to recommend the evaluation of moderate and severe periodontitis for the general population and additionally added the guideline for the individuals without systemic disease including diabetes mellitus, hypertension, metabolic syndrome, and obesity. This study suggests that the participants with certain age may be recommended for the regular periodontal evaluation. PMID:28816984

Geometric morphometric evaluation of cervical vertebrae shape and its relationship to skeletal maturation.

PubMed

Chatzigianni, Athina; Halazonetis, Demetrios J

2009-10-01

Cervical vertebrae shape has been proposed as a diagnostic factor for assessing skeletal maturation in orthodontic patients. However, evaluation of vertebral shape is mainly based on qualitative criteria. Comprehensive quantitative measurements of shape and assessments of its predictive power have not been reported. Our aims were to measure vertebral shape by using the tools of geometric morphometrics and to evaluate the correlation and predictive power of vertebral shape on skeletal maturation. Pretreatment lateral cephalograms and corresponding hand-wrist radiographs of 98 patients (40 boys, 58 girls; ages, 8.1-17.7 years) were used. Skeletal age was estimated from the hand-wrist radiographs. The first 4 vertebrae were traced, and 187 landmarks (34 fixed and 153 sliding semilandmarks) were used. Sliding semilandmarks were adjusted to minimize bending energy against the average of the sample. Principal components analysis in shape and form spaces was used for evaluating shape patterns. Shape measures, alone and combined with centroid size and age, were assessed as predictors of skeletal maturation. Shape alone could not predict skeletal maturation better than chronologic age. The best prediction was achieved with the combination of form space principal components and age, giving 90% prediction intervals of approximately 200 maturation units in the girls and 300 units in the boys. Similar predictive power could be obtained by using centroid size and age. Vertebrae C2, C3, and C4 gave similar results when examined individually or combined. C1 showed lower correlations, signifying lower integration with hand-wrist maturation. Vertebral shape is strongly correlated to skeletal age but does not offer better predictive value than chronologic age.

Regional Evaluation of Groundwater Age Distributions Using Lumped Parameter Models with Large, Sparse Datasets: Example from the Central Valley, California, USA

NASA Astrophysics Data System (ADS)

Jurgens, B. C.; Bohlke, J. K.; Voss, S.; Fram, M. S.; Esser, B.

2015-12-01

Tracer-based, lumped parameter models (LPMs) are an appealing way to estimate the distribution of age for groundwater because the cost of sampling wells is often less than building numerical groundwater flow models sufficiently complex to provide groundwater age distributions. In practice, however, tracer datasets are often incomplete because of anthropogenic or terrigenic contamination of tracers, or analytical limitations. While age interpretations using such datsets can have large uncertainties, it may still be possible to identify key parts of the age distribution if LPMs are carefully chosen to match hydrogeologic conceptualization and the degree of age mixing is reasonably estimated. We developed a systematic approach for evaluating groundwater age distributions using LPMs with a large but incomplete set of tracer data (3H, 3Hetrit, 14C, and CFCs) from 535 wells, mostly used for public supply, in the Central Valley, California, USA that were sampled by the USGS for the California State Water Resources Control Board Groundwater Ambient Monitoring and Assessment or the USGS National Water Quality Assessment Programs. In addition to mean ages, LPMs gave estimates of unsaturated zone travel times, recharge rates for pre- and post-development groundwater, the degree of age mixing in wells, proportion of young water (<60 yrs), and the depth of the boundary between post-development and predevelopment groundwater throughout the Central Valley. Age interpretations were evaluated by comparing past nitrate trends with LPM predicted trends, and whether the presence or absence of anthropogenic organic compounds was consistent with model results. This study illustrates a practical approach for assessing groundwater age information at a large scale to reveal important characteristics about the age structure of a major aquifer, and of the water supplies being derived from it.

The effect of age-at-testing on verbal memory among children following severe traumatic brain injury.

PubMed

Silberg, Tamar; Ahonniska-Assa, Jaana; Levav, Miriam; Eliyahu, Roni; Peleg-Pilowsky, Tamar; Brezner, Amichai; Vakil, Eli

2016-01-01

Memory deficits are a common sequelae following childhood traumatic brain injury (TBI), which often have serious implications on age-related academic skills. The current study examined verbal memory performance using the Rey Auditory Verbal Learning Test (RAVLT) in a pediatric TBI sample. Verbal memory abilities as well as the effect of age at-testing on performance were examined. A sample of 67 children following severe TBI (age average = 12.3 ± 2.74) and 67 matched controls were evaluated using the RAVLT. Age effect at assessment was examined using two age groups: above and below 12 years of age during evaluation. Differences between groups were examined via the 9 RAVLT learning trials and the 7 composite scores conducted out of them. Children following TBI recalled significantly less words than controls on all RAVLT trials and had significantly lower scores on all composite scores. However, all of these scores fell within the low average range. Further analysis revealed significantly lower than average performance among the older children (above 12 years), while scores of the younger children following TBI fell within average limits. To conclude, verbal memory deficits among children following severe TBI demonstrate an age-at-testing effect with more prominent problems occurring above 12 years at the time of evaluation. Yet, age-appropriate performance among children below 12 years of age may not accurately describe memory abilities at younger ages following TBI. It is therefore recommended that clinicians address child's age at testing and avoid using a single test as an indicator of verbal memory functioning post TBI.

20 CFR 416.963 - Your age as a vocational factor.

Code of Federal Regulations, 2013 CFR

2013-04-01

... the older age category after evaluating the overall impact of all the factors of your case. (c... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Your age as a vocational factor. 416.963... age as a vocational factor. (a) General. “Age” means your chronological age. When we decide whether...

The impact of experienced emotion on evaluative judgments: the effects of age and emotion regulation style.

PubMed

Hess, Thomas M; Beale, Karen S; Miles, Amanda

2010-11-01

Adults aged from 24 to 79 were exposed to four commercial advertisements within the context of television programs designed to induce either a positive or negative mood. Although age was associated with memory for the content of the commercials, it did not moderate the impact of mood on evaluations of the advertised products. Instead, participants who reported engaging in expressive suppression as a common emotion regulation strategy were more likely to make evaluations that were biased by moods than those individuals who reported low use of this strategy. The results suggest that the maintenance of emotion regulation ability in later adulthood may help people control certain affective influences on thought.

Nutritional status of children hospitalized in Tabriz Paediatric Hospital, Islamic Republic of Iran, 2008.

PubMed

Mahdavi, A M; Ostadrahimi, A; Safaiyan, A

2011-01-01

This study aimed to evaluate the nutritional status of children consecutively admitted as inpatients to Tabriz Paediatric Hospital in the north-west of the Islamic Republic of Iran between June and August 2008. A total of 140 children aged 2-12 years were included. Patients' weight, height and triceps skinfold thickness (TSFT) were measured, and nutritional status was evaluated. Evaluation of weight-for-age, height-for-age, weight-for-height and TSFT showed that 48.6%, 30.7%, 32.2% and 14.3% of the patients, respectively, were malnourished. Malnutrition among hospitalized children is worthy of attention, and effective strategies for systematic screening and treatment of malnutrition need to be developed and implemented.

Female age-related fertility decline. Committee Opinion No. 589.

PubMed

2014-03-01

The fecundity of women decreases gradually but significantly beginning approximately at age 32 years and decreases more rapidly after age 37 years. Education and enhanced awareness of the effect of age on fertility are essential in counseling the patient who desires pregnancy. Given the anticipated age-related decline in fertility, the increased incidence of disorders that impair fertility, and the higher risk of pregnancy loss, women older than 35 years should receive an expedited evaluation and undergo treatment after 6 months of failed attempts to conceive or earlier, if clinically indicated. In women older than 40 years, more immediate evaluation and treatment are warranted. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

[Evaluating programs for preparation to old age: some theoretical thoughts and a practical example (author's transl)].

PubMed

Schneider, H D

1977-07-01

In the first part methodically satisfactory experimental designs for evaluating programs for preparation to old age on the basis of Cambell & Stanely (1963) are sketched including conditions which hinder the realization of the ideal notions. In the second part an experiment for comparing two preparatory courses to old age using different methods of instruction is described. It was observed that the more demanding teaching method resulted in more anxiety for old age. This led to the conclusion, that programs for preparation to old age should be planned as a sequence of several units in which the mastering of the new ideas may be learned and in which this learning process may be supervised.

Clinical Performance Evaluations of Third-Year Medical Students and Association With Student and Evaluator Gender.

PubMed

Riese, Alison; Rappaport, Leah; Alverson, Brian; Park, Sangshin; Rockney, Randal M

2017-06-01

Clinical performance evaluations are major components of medical school clerkship grades. But are they sufficiently objective? This study aimed to determine whether student and evaluator gender is associated with assessment of overall clinical performance. This was a retrospective analysis of 4,272 core clerkship clinical performance evaluations by 829 evaluators of 155 third-year students, within the Alpert Medical School grading database for the 2013-2014 academic year. Overall clinical performance, assessed on a three-point scale (meets expectations, above expectations, exceptional), was extracted from each evaluation, as well as evaluator gender, age, training level, department, student gender and age, and length of observation time. Hierarchical ordinal regression modeling was conducted to account for clustering of evaluations. Female students were more likely to receive a better grade than males (adjusted odds ratio [AOR] 1.30, 95% confidence interval [CI] 1.13-1.50), and female evaluators awarded lower grades than males (AOR 0.72, 95% CI 0.55-0.93), adjusting for department, observation time, and student and evaluator age. The interaction between student and evaluator gender was significant (P = .03), with female evaluators assigning higher grades to female students, while male evaluators' grading did not differ by student gender. Students who spent a short time with evaluators were also more likely to get a lower grade. A one-year examination of all third-year clerkship clinical performance evaluations at a single institution revealed that male and female evaluators rated male and female students differently, even when accounting for other measured variables.

Growth trajectories of alcohol information processing and associations with escalation of drinking in early adolescence.

PubMed

Colder, Craig R; O'Connor, Roisin M; Read, Jennifer P; Eiden, Rina D; Lengua, Liliana J; Hawk, Larry W; Wieczorek, William F

2014-09-01

This longitudinal study provided a comprehensive examination of age-related changes in alcohol outcome expectancies, subjective evaluation of alcohol outcomes, and automatic alcohol associations in early adolescence. A community sample (52% female, 75% White/non-Hispanic) was assessed annually for 3 years (mean age at the first assessment = 11.6 years). Results from growth modeling suggested that perceived likelihood of positive outcomes increased and that subjective evaluations of these outcomes were more positive with age. Perceived likelihood of negative outcomes declined with age. Automatic alcohol associations were assessed with an Implicit Association Task (IAT), and were predominantly negative, but these negative associations weakened with age. High initial levels of perceived likelihood of positive outcomes at age 11 were associated with escalation of drinking. Perceived likelihood of negative outcomes was associated with low risk for drinking at age 11, but not with changes in drinking. Increases in positive evaluations of positive outcomes were associated with increases in alcohol use. Overall, findings suggest that at age 11, youth maintain largely negative attitudes and perceptions about alcohol, but with the transition into adolescence, there is a shift toward a more neutral or ambivalent view of alcohol. Some features of this shift are associated with escalation of drinking. Our findings point to the importance of delineating multiple aspects of alcohol information processing for extending cognitive models of alcohol use to the early stages of drinking.

Defecography by digital radiography: experience in clinical practice*

PubMed Central

Gonçalves, Amanda Nogueira de Sá; Sala, Marco Aurélio Sousa; Bruno, Rodrigo Ciotola; Xavier, José Alberto Cunha; Indiani, João Mauricio Canavezi; Martin, Marcelo Fontalvo; Bruno, Paulo Maurício Chagas; Nacif, Marcelo Souto

2016-01-01

Objective The objective of this study was to profile patients who undergo defecography, by age and gender, as well as to describe the main imaging and diagnostic findings in this population. Materials and Methods This was a retrospective, descriptive study of 39 patients, conducted between January 2012 and February 2014. The patients were evaluated in terms of age, gender, and diagnosis. They were stratified by age, and continuous variables are expressed as mean ± standard deviation. All possible quantitative defecography variables were evaluated, including rectal evacuation, perineal descent, and measures of the anal canal. Results The majority (95%) of the patients were female. Patient ages ranged from 18 to 82 years (mean age, 52 ± 13 years): 10 patients were under 40 years of age; 18 were between 40 and 60 years of age; and 11 were over 60 years of age. All 39 of the patients evaluated had abnormal radiological findings. The most prevalent diagnoses were rectocele (in 77%) and enterocele (in 38%). Less prevalent diagnoses were vaginal prolapse, uterine prolapse, and Meckel's diverticulum (in 2%, for all). Conclusion Although defecography is performed more often in women, both genders can benefit from the test. Defecography can be performed in order to detect complex disorders such as uterine and rectal prolapse, as well as to detect basic clinical conditions such as rectocele or enterocele. PMID:28100932

National Uranium Resource Evaluation: Newcastle Quadrangle, Wyoming and South Dakota

DOE Office of Scientific and Technical Information (OSTI.GOV)

Santos, E S; Robinson, K; Geer, K A

1982-09-01

Uranium resources of the Newcastle 1/sup 0/x2/sup 0/ Quadrangle, Wyoming and South Dakota were evaluated to a depth of 1500 m (5000 ft) using available surface and subsurface geologic information. Many of the uranium occurrences reported in the literature and in reports of the US Atomic Energy Commission were located, sampled and described. Areas of anomalous radioactivity, interpreted from an aerial radiometric survey, were outlined. Areas favorable for uranium deposits in the subsurface were evaluated using gamma-ray logs. Based on surface and subsurface data, two areas have been delineated which are underlain by rocks deemed favorable as hosts for uraniummore » deposits. One of these is underlain by rocks that contain fluvial arkosic facies in the Wasatch and Fort Union Formations of Tertiary age; the other is underlain by rocks containing fluvial quartzose sandstone facies of the Inyan Kara Group of Early Cretaceous age. Unfavorable environments characterize all rock units of Tertiary age above the Wasatch Formation, all rock units of Cretaceous age above the Inyan Kara Group, and most rock units of Mesozoic and Paleozoic age below the Inyan Kara Group. Unfavorable environments characterize all rock units of Cretaceous age above the Inyan Kara Group, and all rock units of Mesozoic and Paleozoic age below the Inyan Kara Group.« less

76 FR 17929 - National Institute on Aging; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-31

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... unwarranted invasion of personal privacy. Name of Committee: National Institute on Aging Special Emphasis...: To review and evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201...

75 FR 9908 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-04

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Health, Behavior... and evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin...

77 FR 2737 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-19

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Development and....m. Agenda: To review and evaluate contract proposals. Place: National Institute on Aging, Gateway...

75 FR 26268 - National Institute on Aging; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-11

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, ARRA--Behavioral... evaluate grant applications. Place: National Institute on Aging, Gateway Building, 7201 Wisconsin Avenue...

The third molar as an age marker in adolescents: new approach to age evaluation.

PubMed

Rozkovcova, Eva; Dostalova, Tatjana; Markova, Marie; Broukal, Zdenek

2012-09-01

Adolescence is a relatively short period between childhood and adulthood. It is very difficult to determine adulthood based on biological indicators. The third molar may be considered a potential age marker for the period between the ages of 16-21. Our study evaluated a set of 1700 panoramic radiographs of individuals aged between 5 and 21 years. Results confirmed the statistically significant difference in the course of third molars development. The mean deviation for individuals with one third molar agenesis is -0.98 years, for individuals with two third molars agenesis -1.89 years, and with three molars agenesis -3.28 years. Thus, the extent of the deviation is directly proportional to the number of unformed third molars. The calculation of age according to the mean of stages of all third molars could lead to the underestimation of age. No intergender differences were found. Age determination using third molars could be used for forensic purposes. © 2012 American Academy of Forensic Sciences.

Effect of root canal sealer and artificial accelerated aging on fibreglass post bond strength to intraradicular dentin.

PubMed

Santana, Fernanda-Ribeiro; Soares, Carlos-José; Ferreira, Josemar-Martins; Valdivi, Andréa-Dolores-Correia-Miranda; Souza, João-Batista-de; Estrela, Carlos

2014-10-01

To evaluate the effect of root canal sealers (RCS) and specimen aging on the bond strength of fibre posts to bovine intraradicular dentin. 80 teeth were used according the groups - Sealapextm, Sealer 26®, AH Plus® and specimens aging - test with no aging and with aging. The canals prepared were filled using one of each RCS. The posts were cemented. Roots were cross-sectioned to obtain two slices of each third. Samples were submitted to push-out test. Failure mode was evaluated under a confocal microscope. The data were analysed by ANOVA, Tukey's, and Dunnet tests (α = 0.05). No significant difference was detected among RCS. Aged control presented higher bond strength than immediate control. The aging did not result significant difference. Adhesive cement-dentin failure was prevalent in all groups. RCS interfered negatively with bonding of fibreglass posts cemented with self-adhesive resin cement to intraradicular dentin. Key words:Fibreglass post, bond strength, root dentin, endodontic sealer, aging.

Evaluating Age Differences in Coping Motives as a Mediator of the Link between Social Anxiety Symptoms and Alcohol Problems

PubMed Central

Clerkin, Elise M.; Werntz, Alexandra J.; Magee, Joshua C.; Lindgren, Kristen P.; Teachman, Bethany A.

2014-01-01

The goal of this study is to evaluate whether coping motives mediate the relationship between self-reported symptoms of social anxiety and alcohol problems across different age groups, building upon previous research conducted among emerging adults. This study focuses on adult drinkers, including emerging adults (age 18–25; n = 148), young adults (age 26–39; n = 68), and middle-aged adults (age 40–65; n = 51). All participants completed measures of social anxiety symptoms, alcohol problems, and coping motives, administered via the web. Invariance tests using structural equation modeling suggested that among emerging adults (and to some degree middle-aged adults), coping motives mediated the positive relationship between symptoms of social anxiety and alcohol problems. Interestingly, coping motives appeared to suppress a negative relationship between social anxiety and alcohol problems in young adults. Results suggest that it is critical to consider age differences when attempting to understand the relationships between symptoms of social anxiety, alcohol problems, and coping motives. PMID:24841182

Evaluating age differences in coping motives as a mediator of the link between social anxiety symptoms and alcohol problems.

PubMed

Clerkin, Elise M; Werntz, Alexandra J; Magee, Joshua C; Lindgren, Kristen P; Teachman, Bethany A

2014-09-01

The goal of this study is to evaluate whether coping motives mediate the relationship between self-reported symptoms of social anxiety and alcohol problems across different age groups, building on previous research conducted among emerging adults. This study focuses on adult drinkers, including emerging adults (aged 18-25 years; n = 148), young adults (aged 26-39 years; n = 68), and middle-aged adults (aged 40-65 years; n = 51). All participants completed measures of social anxiety symptoms, alcohol problems, and coping motives, administered via the Web. Invariance tests using structural equation modeling suggested that among emerging adults (and to some degree middle-aged adults), coping motives mediated the positive relationship between symptoms of social anxiety and alcohol problems. Interestingly, coping motives appeared to suppress a negative relationship between social anxiety and alcohol problems in young adults. Results suggest that it is critical to consider age differences when attempting to understand the relationships between symptoms of social anxiety, alcohol problems, and coping motives.

Evaluation of morphological changes in the adult skull with age and sex.

PubMed

Urban, Jillian E; Weaver, Ashley A; Lillie, Elizabeth M; Maldjian, Joseph A; Whitlow, Christopher T; Stitzel, Joel D

2016-12-01

The morphology of the brain and skull are important in the evaluation of the aging human; however, little is known about how the skull may change with age. The objective of this study was to evaluate the morphological changes of the adult skull using three-dimensional geometric morphometric analysis of thousands of landmarks with the focus on anatomic regions that may be correlated with brain atrophy and head injury. Computed tomography data were collected between ages 20 and 100. Each scan was segmented using thresholding techniques. An atlas image of a 50th percentile skull was registered to each subject scan by computing a series of rigid, affine, and non-linear transformations between atlas space and subject space. Landmarks on the atlas skull were transformed to each subject and partitioned into the inner and outer cranial vault and the cranial fossae. A generalized Procrustes analysis was completed for the landmark sets. The coordinate locations describing the shape of each region were regressed with age to generate a model predicting the landmark location with age. Permutation testing was performed to assess significant changes with age. For the males, all anatomic regions reveal significant changes in shape with age except for the posterior cranial fossa. For the females, only the middle cranial fossa and anterior cranial fossa were found to change significantly in shape. Results of this study are important for understanding the adult skull and how shape changes may pertain to brain atrophy, aging, and injury. © 2014 Anatomical Society.

Effect of castration and slaughter age on performance, carcass, and meat quality traits of Holstein calves fed a high-concentrate diet.

PubMed

Marti, S; Realini, C E; Bach, A; Pérez-Juan, M; Devant, M

2013-03-01

The aim of this study was to evaluate the effect of castration and slaughter age on performance and meat quality of Holstein bulls fed a high-concentrate diet. A total of 132 animals (116 ± 3.7 kg of BW and 97 ± 2.4 d of age) were randomly allocated in 6 pens using a 3 × 3 factorial arrangement of treatments. Three castration ages [bulls, animals castrated at 3 mo (CAS3), and animals castrated at 8 mo of age (CAS8)] and 3 slaughter ages (10, 12, and 14 mo of age) were evaluated. Feed intake was recorded daily using a computerized concentrate feeder, and BW was recorded every 14 d. The 9th to 11th rib section was removed at 24 h postmortem and dissected into lean, fat, and bone, and meat quality was evaluated on the LM. Castration, at 3 or 8 mo of age, reduced (P < 0.001) ADG and muscle pH and impaired (P < 0.01) feed efficiency. As slaughter age increased, concentrate consumption increased linearly (P < 0.001) and feed efficiency was reduced linearly (P < 0.001). Slaughter age also affected (P < 0.001) meat pH. Significant interactions between castration and slaughter ages were also observed in carcass conformation (P < 0.05), fatness (P < 0.001), percentage of subcutaneous fat (P < 0.01), carcass dressing percentage (P < 0.05), and intramuscular fat (P < 0.05) and tended to be significant in intermuscular fat (P = 0.09). In Holstein animals, castration age affects performance and meat pH regardless of slaughter age, and slaughter age affects performance and meat pH independently of castration. However, in Holstein animals, castration affects several characteristics related to fat deposition differently depending on slaughter age, such as carcass fat cover and intramuscular, intermuscular, and subcutaneous fat.

Evaluating the Functional Utility of Congregate Day Treatment Activities for Adults with Severe Disabilities.

ERIC Educational Resources Information Center

Reid, Dennis H.; Parsons, Marsha B.; Green, Carolyn W.

2001-01-01

Observations in 100 congregated community and institutional day-program sites for individuals with severe disabilities indicated that approximately half of consumer time was spent in purposeful activity, 75 percent of which was age-appropriate. In 20 percent of the sites most activity was age-inappropriate. Recommended program evaluation and…

Reframing Resilience: Pilot Evaluation of a Program to Promote Resilience in Marginalized Older Adults

ERIC Educational Resources Information Center

Fullen, Matthew C.; Gorby, Sean R.

2016-01-01

Resilience has been described as a paradigm for aging that is more inclusive than models that focus on physiological and functional abilities. We evaluated a novel program, Resilient Aging, designed to influence marginalized older adults' perceptions of their resilience, self-efficacy, and wellness. The multiweek group program incorporated an…

Attachment and Self-Evaluation in Chinese Adolescents: Age and Gender Differences

ERIC Educational Resources Information Center

Song, Hairong; Thompson, Ross A.; Ferrer, Emilio

2009-01-01

This study investigated age and gender differences in the quality of attachment to mothers, fathers, and peers, and the association of attachment with measures of self-evaluation in 584 Chinese adolescents in junior high, high school, and university. Their responses to the Inventory of Parent and Peer Attachment indexed attachment quality, and…

The Neuromotor Examination of the Preschool Child and Its Prognostic Significance

ERIC Educational Resources Information Center

Hadders-Algra, Mijna

2005-01-01

The present paper reviews the methods available for neurological or neuromotor evaluation at preschool age. General textbooks on pediatric neurology describe the neurological examination at preschool age in terms of the assessment of the evaluation of cranial nerves, muscle tone, muscle power, reflexes, and the presence of abnormal movements. They…

Longitudinal change in the neural bases of adolescent social self-evaluations: effects of age and pubertal development.

PubMed

Pfeifer, Jennifer H; Kahn, Lauren E; Merchant, Junaid S; Peake, Shannon J; Veroude, Kim; Masten, Carrie L; Lieberman, Matthew D; Mazziotta, John C; Dapretto, Mirella

2013-04-24

Self-evaluations undergo significant transformation during early adolescence, developing in parallel with the heightened complexity of teenagers' social worlds. Intuitive theories of adolescent development, based in part on animal work, suggest that puberty is associated with neural-level changes that facilitate a "social reorientation" (Nelson et al., 2005). However, direct tests of this hypothesis using neuroimaging are limited in humans. This longitudinal fMRI study examined neurodevelopmental trajectories associated with puberty, self-evaluations, and the presumed social reorientation during the transition from childhood to adolescence. Participants (N = 27, mean age = 10.1 and 13.1 years at time points one and two, respectively) engaged in trait evaluations of two targets (the self and a familiar fictional other), across two domains of competence (social and academic). Responses in ventromedial PFC increased with both age and pubertal development during self-evaluations in the social domain, but not in the academic domain. These results suggest that changes in social self-evaluations are intimately connected with biology, not just peer contexts, and provide important empirical support for the relationship between neurodevelopment, puberty, and social functioning.

Increased deficits in emotion recognition and regulation in children and adolescents with exogenous obesity.

PubMed

Percinel, Ipek; Ozbaran, Burcu; Kose, Sezen; Simsek, Damla Goksen; Darcan, Sukran

2018-03-01

In this study we aimed to evaluate emotion recognition and emotion regulation skills of children with exogenous obesity between the ages of 11 and 18 years and compare them with healthy controls. The Schedule for Affective Disorders and Schizophrenia for School Aged Children was used for psychiatric evaluations. Emotion recognition skills were evaluated using Faces Test and Reading the Mind in the Eyes Test. The Difficulties in Emotions Regulation Scale was used for evaluating skills of emotion regulation. Children with obesity had lower scores on Faces Test and Reading the Mind in the Eyes Test, and experienced greater difficulty in emotional regulation skills. Improved understanding of emotional recognition and emotion regulation in young people with obesity may improve their social adaptation and help in the treatment of their disorder. To the best of our knowledge, this is the first study to evaluate both emotional recognition and emotion regulation functions in obese children and obese adolescents between 11 and 18 years of age.

77 FR 74677 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-17

... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Cell Dependent and... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... and evaluate grant applications. Place: National Institute on Aging, Gateway Building, Suite 2C212...

An Epidemiologic Study on Ageing and Dysphagia in the Acute Care Geriatric-Hospitalized Population: A Replication and Continuation Study.

PubMed

Leder, Steven B; Suiter, Debra M; Agogo, George O; Cooney, Leo M

2016-10-01

United States census data project dramatic increases in the geriatric population ageing demographics by 2060 with concomitant health-care consequences. The purpose of this replication and continuation study was to collect new 2014 demographic data relative to ageing, swallow evaluation referral rates, and oral feeding status in geriatric-hospitalized patients for comparison with published data from 2000 to 2007. This was a planned data acquisition study of consecutive hospitalized patients referred for swallow assessments. Swallow evaluation referral rates for 2014 were described according to inpatient discharges, age range 60-105 years grouped by decade, gender, admitting diagnostic category, results of swallow evaluations, and oral feeding status. Determination of aspiration risk status was made with the Yale Swallow Protocol and diagnosis of dysphagia made with fiberoptic endoscopic evaluation of swallowing (FEES). There were 1348 referrals and 961 patients ≥60 years of age participated. Overall swallow evaluation referral rates increased an average of 63 % between the comparison years 2007 and 2014 with consistent increases corresponding to the decades, i.e., 60-69 (46 %), 70-79 (68 %), 80-89 (53 %), and 90+ (222 %). A total of 75 % of participants resumed oral alimentation and oral medications. Swallow evaluation referral rates increased by 63 % for 60-90+ year-old acute care geriatric-hospitalized participants despite only a 23 % increase in inpatient discharges for the years 2007 versus 2014. This corroborated previously reported increases for individual years from 2000 to 2007. For timely, safe, and successful initiation of oral alimentation, it is important to perform a reliable swallow screen for aspiration risk assessment with the Yale Swallow Protocol and, if failed, instrumental testing with FEES. More dysphagia specialists are needed through 2060 and beyond due to projections of continued population ageing resulting in ever increasing referral rates for swallow assessments.

Three-dimensional measurement of foot arch in preschool children

PubMed Central

2012-01-01

Background The prevalence of flexible flatfoot is high among preschool-aged children, but the effects of treatment are inconclusive due to the unclear definitions of normal flatfoot. To date, a universally accepted evaluation method of the foot arch in children has not been completely established. Our aims of this study were to establish a new method to evaluate the foot arch from a three dimensional perspective and to investigate the flexibility of the foot arch among children aged from two to six. Methods A total of 44 children aged from two to six years of age were put into five age groups in this study. The navicular height was measured with one leg standing, and both feet were scanned separately in both sitting and one leg standing positions to compute the foot arch volume. The arch volume index, which represents the ratio of the difference in volume between sitting and one leg standing positions to the volume when sitting was calculated to demonstrate the flexibility of the foot arch. The differences of measured parameters between each aged group were analyzed by one-way ANOVA. Results The arch volumes when sitting and standing were highly correlated with the navicular height. The navicular height ranged from 15.75 to 27 mm, the arch volume when sitting ranged from 6,223 to 11,630 mm3, and the arch volume when standing from 3,111 to 7,848 mm3 from two to six years of age. The arch volume index showed a declining trend as age increased. Conclusion This study is the first to describe the foot arch with volume perspective in preschool-aged children. The foot arch volume was highly correlated with the navicular height. Research results show both navicular height index and arch volume index gradually increase with age from two to six. At the same time the arch also becomes rigid with age from two to six. These results could be applied for clinical evaluation of the foot arch and post-treatment evaluation. PMID:23009315

Effect of Different In Vitro Aging Methods on Color Stability of a Dental Resin-Based Composite Using CIELAB and CIEDE2000 Color-Difference Formulas.

PubMed

de Oliveira, Dayane Carvalho Ramos Salles; Ayres, Ana Paula Almeida; Rocha, Mateus Garcia; Giannini, Marcelo; Puppin Rontani, Regina Maria; Ferracane, Jack L; Sinhoreti, Mario Alexandre Coelho

2015-01-01

To evaluate the effect of different in vitro aging methods on color change (CC) of an experimental dental resin-based composite using CIELAB (ΔEab ) and CIEDE2000 (ΔE00 ) color-difference formulas. The CC was evaluated with a spectrophotometer (CM700d, Konica Minolta, Tokyo, Japan) according to the CIE chromatic space. Disk-shaped specimens (Φ = 5 × 1 mm thick) (N = 10) were submitted to different in vitro aging methods: 30 days of water aging (WA); 120 hours of ultraviolet light aging (UVA); or 300 hours of an accelerated artificial aging (AAA) method with cycles of 4 hours of UV-B light exposure and 4 hours of moisture condensation to induce CC. The temperature was standardized at 37°C for all aging methods. CC was evaluated with ΔEab and ΔE00 formulas. Differences in individual Lab coordinates were also calculated. Data for the individual color parameters were submitted to one-way analysis of variance and Tukey's test for multiple comparisons (α = 0.05). All in vitro aging methods tested induced CC, in the following order: WA: ΔEab = 0.83 (0.1); ΔE00  = 1.15 (0.1) < AAA: ΔEab  = 5.64 (0.2); ΔE00  = 5.01 (0.1) < UVA: ΔEab  = 6.74 (0.2); ΔE00  = 6.03 (0.4). No changes in L* or a* coordinates were ≥1; the methods with UV aging showed a yellowing effect due a large positive change in b*. All in vitro aging methods tested induced a CC, but to different extents. Changes in color followed similar trends, but with different absolute values when calculated with the CIELAB and the CIEDE2000 formulas. Establishing the efficacy of different artificial aging methods and differences between color change using CIELAB and CIEDE2000 formulas are important to standardize color stability evaluations and facilitate the comparison of outcomes from different studies in the literature. © 2015 Wiley Periodicals, Inc.

Evaluation of age determination techniques for gray wolves

USGS Publications Warehouse

Landon, D.B.; Waite, C.A.; Peterson, R.O.; Mech, L.D.

1998-01-01

We evaluated tooth wear, cranial suture fusion, closure of the canine pulp cavity, and cementum annuli as methods of age determination for known- and unknown-age gray wolves (Canis lupus) from Alaska, Minnesota, Ontario, and Isle Royale, Michigan. We developed age classes for cranial suture closure and tooth wear. We used measurement data obtained from known-age captive and wild wolves to generate a regression equation to predict age based on the degree of closure of the canine pulp cavity. Cementum annuli were studied in known- and unknown-age animals, and calcified, unstained thin sections were found to provide clear annulus patterns under polarized transmitted light. Annuli counts varied among observers, partly because of variation in the pattern of annuli in different regions of the cementum. This variation emphasizes the need for standardized models of cementum analysis. Cranial suture fusion is of limited utility in age determination, while tooth wear can be used to estimate age of adult wolves within 4 years. Wolves lt 7 years old could be aged to within 13 years with the regression equation for closure of the canine pulp cavity. Although inaccuracy remains a problem, cementum-annulus counts were the most promising means of estimating age for gray wolves.

Enhancing Medical Decision-Making Evaluations: Introduction of Normative Data for the Capacity to Consent to Treatment Instrument.

PubMed

Gerstenecker, Adam; Niccolai, Lindsay; Marson, Daniel; Triebel, Kristen L

2016-04-01

A number of measures have been developed to assess medical decision-making capacity (MDC) in adults. However, their clinical utility is limited by a lack of available normative data. In the current study, we introduce age-independent and age-adjusted normative data for a measure of MDC: the Capacity to Consent to Treatment Instrument. The sample consisted of 308 cognitively normal, community-dwelling adults ranging in age from 19 to 86 years. For age-adjusted norms, individual raw scores were first converted to age-corrected scaled scores based on position within a cumulative frequency distribution and then grouped according to empirically supported age ranges. For age-independent norms, the same method was utilized but without age-corrections being applied or participants being grouped into age ranges. This study has the potential to enhance MDC evaluations by allowing clinicians to compare a patient's performance on the Capacity to Consent to Treatment Instrument with that of adults regardless of age as well as to same age peers. Tables containing normative corrections are supplementary material available online at http://asm.sagepub.com/supplemental. © The Author(s) 2015.

Measuring future time perspective across adulthood: development and evaluation of a brief multidimensional questionnaire.

PubMed

Brothers, Allyson; Chui, Helena; Diehl, Manfred

2014-12-01

Despite calls for the consideration of future time perspective (FTP) as a multidimensional construct, mostly unidimensional measurement instruments have been used. This study had two objectives: (a) to develop a brief multidimensional questionnaire for assessing FTP in adulthood and evaluate its psychometric properties; and (b) to examine age associations and age-group differences of the dimensions of FTP. Data were collected from 625 community-residing adults between the ages of 18 and 93, representing young, middle-aged, and older adults. The psychometric evaluation involved exploratory factor analyses (EFA) and confirmatory FA (CFA), reliability and validity analyses, and measurement invariance testing. Zero-order and partial correlations were used to examine the association of the dimensions of FTP with age, and multivariate analysis of variance was used to examine age-group differences. EFA and CFA supported a three-factor solution: Future as Open, Future as Limited, and Future as Ambiguous. Metric measurement invariance for this factor structure was confirmed across the three age groups. Reliability and validity analyses provided evidence of sound psychometric properties of the brief questionnaire. Age was negatively associated with Future as Open and positively associated with Future as Limited. Young adults exhibited significantly greater ambiguity toward the future than middle-aged or older adults. This study provides evidence in support of the psychometric properties of a new brief multidimensional FTP scale. It also provides evidence for a pattern of age associations and age-group differences consistent with life-span developmental theory. © The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Comparison of the diagnostic accuracy, sensitivity and specificity of four odontological methods for age evaluation in Italian children at the age threshold of 14 years using ROC curves.

PubMed

Pinchi, Vilma; Pradella, Francesco; Vitale, Giulia; Rugo, Dario; Nieri, Michele; Norelli, Gian-Aristide

2016-01-01

The age threshold of 14 years is relevant in Italy as the minimum age for criminal responsibility. It is of utmost importance to evaluate the diagnostic accuracy of every odontological method for age evaluation considering the sensitivity, or the ability to estimate the true positive cases, and the specificity, or the ability to estimate the true negative cases. The research aims to compare the specificity and sensitivity of four commonly adopted methods of dental age estimation - Demirjian, Haavikko, Willems and Cameriere - in a sample of Italian children aged between 11 and 16 years, with an age threshold of 14 years, using receiver operating characteristic curves and the area under the curve (AUC). In addition, new decision criteria are developed to increase the accuracy of the methods. Among the four odontological methods for age estimation adopted in the research, the Cameriere method showed the highest AUC in both female and male cohorts. The Cameriere method shows a high degree of accuracy at the age threshold of 14 years. To adopt the Cameriere method to estimate the 14-year age threshold more accurately, however, it is suggested - according to the Youden index - that the decision criterion be set at the lower value of 12.928 for females and 13.258 years for males, obtaining a sensitivity of 85% and specificity of 88% in females, and a sensitivity of 77% and specificity of 92% in males. If a specificity level >90% is needed, the cut-off point should be set at 12.959 years (82% sensitivity) for females. © The Author(s) 2015.

Age-specific performance of careHPV versus Papanicolaou and visual inspection of cervix with acetic acid testing in a primary cervical cancer screening.

PubMed

Labani, Satyanarayana; Asthana, Smita

2016-01-01

Human papillomavirus (HPV) is recommended as a primary screening tool for cervical screening. Assessment of age-specific performance of newer HPV careHPV DNA testing is important as risk of cervical intraepithelial neoplasia (CIN) varies at different ages. We aim to evaluate careHPV in comparison to Papanicolaou (Pap) test and visual inspection of the cervix with acetic acid (VIA) cervical screening tests for the detection of high-grade CIN. The cross sectional study was conducted in a rural population of North India. Ever-married women 30-59 years of age were invited for screening by careHPV (self-collected vaginal and physician-collected cervical samples), Pap test and VIA. Associations for trend in age for detecting histological-confirmed CINII+ and CINIII+ for each screening test were evaluated. Age-specific association with each screening test was evaluated. Of a total of 7761 women invited, 5032 were screened and analysis was performed on 4658 with all screen test results. No significant (p>0.05) association of age for any screening test in the detection of CINII+ or CINIII+ was observed. For the older age group, cervical HPV (CHPV) showed high sensitivity and specificity for CINII+ detection. Specificity of CHPV or vaginal HPV (VHPV) was equal or higher than Pap in all age groups. Cervical screening options of CHPV or VHPV, or Pap, performed equally in the younger age group while CHPV might be an option for all ages in the detection of high-grade CIN. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

The impact of physical activity on endothelial function in middle-aged and elderly subjects: the Ikaria study.

PubMed

Siasos, Gerasimos; Chrysohoou, Christina; Tousoulis, Dimitris; Oikonomou, Evangelos; Panagiotakos, Demosthenes; Zaromitidou, Marina; Zisimos, Konstantinos; Marinos, Georgios; Mazaris, Savvas; Kampaksis, Manolis; Papavassiliou, Athanasios G; Pitsavos, Christos; Stefanadis, Christodoulos

2013-01-01

Exercise training and physical activity (PA) have substantial vascular and cardiac health benefits. Ikaria Island has been recognised as having one of the highest longevity rates worldwide and a high percentage of healthy ageing. We examined the relationship between endothelial function and levels of habitual PA to evaluate the factors related to healthy ageing in this population. The study was conducted on a subgroup population of the IKARIA study consisting of 185 middle-aged (40-65 years) and 142 elderly subjects (66-91 years). Endothelial function was evaluated by ultrasound measurement of flow-mediated dilatation (FMD). PA was evaluated using the shortened version of the self-reported International Physical Activity Questionnaire (IPAQ). Subjects in the low PA group (<500 MET/ min/week) were considered as physically inactive and the rest as active. In the overall study population FMD was inversely associated with age (r=-0.24, p<0.001) and middle-aged subjects had higher FMD compared with the elderly (6.26 ± 3.31% vs. 5.21 ± 2.95%, p=0.003). Multiple linear regression analysis revealed that among middle-aged subjects the physically active had higher FMD compared with the physically inactive. Physically active subjects in the middle-aged group showed higher FMD compared with the physically active elderly (p=0.008). However, there was no difference in FMD values between middle-aged inactive subjects and the elderly physically active (p=NS). The present study revealed that increased PA was associated with improved endothelial function in middle-aged subjects and that PA in elderly subjects can ameliorate the devastating effects of ageing on arterial wall properties.

Consumer sensory acceptance and value of wet-aged and dry-aged beef steaks.

PubMed

Sitz, B M; Calkins, C R; Feuz, D M; Umberger, W J; Eskridge, K M

2006-05-01

To determine sensory preference and value of fresh beef steak differing in aging technique, strip steaks were evaluated by consumers in Denver (n = 132 consumers) and Chicago (n = 141 consumers). Wet-aged Choice strip loins were matched with dry-aged Choice strip loins, whereas wet-aged Prime strip loins were matched with dry-aged Prime strip loins. Dry-aged strip loins were commercially aged in air in a controlled environment for 30 d and vacuum-aged for 7 d during shipping and storage. Wet-aged strip loins were vacuum-packaged and aged for 37 d in a 1 degrees C cooler. Pairs of strip loins were matched to similar Warner-Bratzler shear force values and marbling scores. Twelve sensory evaluation panels (of 12 scheduled panelists each) were conducted over a 3-d period in each city. Individual samples from a pair of steaks were evaluated by the panelists for sensory traits. Bids were placed on the samples after sensory traits were obtained utilizing a variation of the Vickery auction with silent, sealed bids. No significant differences for sensory traits of flavor, juiciness, tenderness, or overall acceptability were detected between wet-aged Choice samples and dry-aged Choice samples. Although wet-aged Choice samples were numerically superior for all sensory traits, consumers placed similar bid values (P = 0.12) on wet- and dry-aged Choice samples ($3.82 per 0.45 kg and $3.57 per 0.45 kg, respectively). Wet-aged Prime samples were rated more desirable (P < 0.001) for flavor, tenderness, and overall acceptability than dry-aged Prime samples. Wet-aged Prime samples were valued at $4.02 per 0.45 kg, whereas dry-aged Prime samples brought $3.58 per 0.45 kg (P = 0.008). Consumers (29.3%) who preferred the dry-aged Choice samples over the wet-aged Choice samples were willing to pay $1.99/0.45 kg more (P < 0.001) for dry-aged samples. The consumers who preferred the wet-aged Choice over the dry-aged Choice samples (39.2%) were willing to pay $1.77/0.45 kg more (P < 0.0001). Consumers who preferred wet-aged Prime over dry-aged Prime samples (45.8%) paid $1.92/0.45 kg more (P < 0.0001). Consumers who preferred dry-aged Prime samples (27.5%) were willing to pay $1.92/0.45 kg more than for the wet-aged Prime samples. Although more consumers preferred wet-aged samples, markets do exist for dry-aged beef, and consumers are willing to pay a premium for this product.

Ground-layer plant community responses to even-age and uneven-age silvicultural treatments in Wisconsin northern hardwood forests

Treesearch

Cristel C. Kern; Brian J. Palik; Terry F. Strong

2006-01-01

We evaluated ground-layer plant diversity and community composition in northern hardwood forests among uncut controls and stands managed with even-age or uneven-age silvicultural systems. Even-age treatments included diameter-limit cuttings (20-cm diameter at 30-cm stem height) in 1952 and shelterwood removals in 1964. Uneven-age treatments included three intensities...

Evaluation of combined effects of ageing period and freezing rate on quality attributes of beef loins.

PubMed

Kim, Yuan H Brad; Liesse, Charlotte; Kemp, Robert; Balan, Prabhu

2015-12-01

The objective of our study was to evaluate the combined effects of ageing period and different freezing rates on meat quality attributes of beef loins. Pairs of loins (M. longissimus at 1 day post mortem) from 12 carcasses were divided into four equal portions and randomly assigned to four ageing/freezing treatments (aged only, frozen only, and 3 or 4 weeks ageing at -1.5°C then frozen). Two freezing methods (fast freezing by calcium chloride immersion or slow freezing by air freezer at -18°C) were applied to the loin sections. Fast freezing had no effect on shear force (P>0.05), but significantly improved the water-holding capacity of the aged/frozen loins by reducing purge and drip losses. Ageing-then-freezing significantly improved shear force values of loins compared to both the aged only and frozen only loins. These observations suggest that fast freezing will add more value to the aged/frozen/thawed meat by minimising the amount of water-loss due to the freezing/thawing process. Copyright © 2015 Elsevier Ltd. All rights reserved.

Performance evaluation of two black nickel and two black chrome solar collectors

NASA Technical Reports Server (NTRS)

Losey, R.

1977-01-01

The test program was based on the evaluation of four unique solar collectors described below: (1) black nickel collector surface with a desiccant drying bed, (2) black nickel collector surface without a desiccant drying bed, (3) black chrome collector surface with a dessicant drying bed, and (4) black chrome collector surface without a desiccant drying bed. The test program included three distinct phases: Initial performance evaluation, natural environmental aging, and post-aging performance evaluation. Results of Phase III testing conclusively indicated a higher normalized efficiency for Black Chrome surfaces when compared to Black Nickel.

Evaluative ratings and attention across the life span: emotional arousal and gender.

PubMed

Ferrari, Vera; Bruno, Nicola; Chattat, Rabih; Codispoti, Maurizio

2017-04-01

This study was designed to investigate the evolution of emotional processing over the whole adult life span as a function of stimulus arousal and participants' gender. To this end, self-reported affective evaluation and attentional capture prompted by pleasant and unpleasant pictures varying in arousal were measured in a large sample of participants (n = 211) balanced by gender and equally spread across seven decades from 20 to 90 years. Results showed age differences only for affective evaluation of pleasant stimuli, with opposite patterns depending on stimulus arousal. As age increased, low-arousing pleasant cues (e.g. images of babies) were experienced as more pleasant and arousing by both males and females, whereas high-arousing stimuli (e.g. erotic images) were experienced as less pleasant only by females. In contrast, emotional pictures (both pleasant and unpleasant) were effective at capturing attention in a similar way across participants, regardless of age and gender. Taken together, these findings suggest that specific emotional cues prompt different subjective responses across different age groups, while basic mechanisms involved in attentional engagement towards both pleasant and unpleasant stimuli are preserved in healthy ageing.

Influence of gender, age and motives underlying food choice on perceived healthiness and willingness to try functional foods.

PubMed

Ares, Gastón; Gámbaro, Adriana

2007-07-01

The aims of the present study were to study the effect of different carriers and enrichments on the perceived healthiness and willingness to try functional foods; and to evaluate the effect of age, gender and motives underlying food choice. Participants had to evaluate different functional food concepts and had to answer a food choice questionnaire. Results showed that carrier products had the largest effect on consumers' perception of healthiness and willingness to try of the evaluated functional foods concepts. The highest positive relative utilities were achieved when the enrichment was a functional ingredient inherent in the product. Furthermore, gender, age and motives underlying food choice affected the preference patterns for the evaluated functional foods concepts, but it depended on the carrier and enrichment considered, suggesting that functional foods might not be accepted by all the consumers and that they could be tailored for certain groups.

Development and Evaluation of an Instrument to Measure Reasoning About Managing Asthma in Older School-Age Children and Adolescents

PubMed Central

Kintner, Eileen; Cook, Gwendolyn; Hull, Lakisha; Meeder, Linda

2018-01-01

Background and Purpose This article describes development and evaluation of a 4-scenario instrument designed to measure reasoning abilities for managing asthma symptoms. Methods Existing literature informed creation of a reasoning template and the reasoning scenarios. Think-aloud interviews appraised scenario functionality. Experts assessed content validity. Data from 2 groups of students with asthma aged 9–15 years (N = 132 and 307) were used to evaluate psychometric properties. Results The scenarios were deemed functional, content was relevant, and readability was age/grade appropriate. Cronbach’s alpha was 0.79. Exploratory and confirmatory factor analyses indicated a single component solution and revealed a good fit. Concurrent validity was established using correlations with asthma knowledge. Conclusion The instrument could be used to assess reasoning about symptom management and to evaluate educational interventions. PMID:24620511

75 FR 39698 - National Institute on Aging; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-12

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel, Network Infrastructure for Aging Research. Date: July 20, 2010. Time: 12 p.m. to 4 p.m. Agenda: To review and evaluate...

75 FR 63497 - National Institute on Aging; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-15

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Genetic Determinants of Healthy Aging. Date: November 10, 2010. Time: 1 p.m. to 5 p.m. Agenda: To review and evaluate...

Age-Dependent Changes in Human Hepatic CYP2C8 and 1A2 Expression

EPA Science Inventory

Predicting age-specific metabolism of pyrethroids is important in evaluating age-related sensitivity. Our goal is to use an in vitro to in vivo extrapolation (IVIVE) approach to predict pyrethroid metabolism for different ages incorporating enzyme ontogeny and expressed enzyme ki...

Psychoeducational Intervention for Sexuality with the Aged, Family Members of the Aged, and People Who Work with the Aged.

ERIC Educational Resources Information Center

White, Charles B.; Catania, Joseph A.

1982-01-01

Conducted and evaluated a sexual psychoeducational intervention with older persons, adult family members of older persons, and staff members of nursing homes. Results indicated significant changes in attitudes toward and knowledge about sexuality and aging and sexual behavior. (Author)

Preschool Personality Antecedents of Narcissism in Adolescence and Emergent Adulthood: A 20-Year Longitudinal Study

PubMed Central

Carlson, Kevin S.; Gjerde, Per F.

2009-01-01

This prospective study examined relations between preschool personality attributes and narcissism during adolescence and emerging adulthood. We created five a priori preschool scales anticipated to foretell future narcissism. Independent assessors evaluated the participants' personality at ages 14, 18, and 23. Based upon these evaluations, we generated observer-based narcissism scales for each of these three ages. All preschool scales predicted subsequent narcissism, except Interpersonal Antagonism at age 23. According to mean scale and item scores analyses, narcissism increased significantly from age 14 to 18, followed by a slight but non-significant decline from age 18 to 23. The discussion focused on a developmental view of narcissism, the need for research on automatic processing and psychological defenses, and links between narcissism and attachment. PMID:20161614

Age differences in goals: implications for health promotion.

PubMed

Zhang, Xin; Fung, Helene; Ching, Bob Ho-hong

2009-05-01

Socioemotional selectivity theory postulates that, as people age, they prioritize emotionally meaningful goals. This study investigated whether these age differences in goals are reflected in how younger (aged 18-36, n = 111) and older adults (aged 62-86, n = 104) evaluated, remembered information from and were persuaded by health messages. Participants were randomly assigned to read health pamphlets with identical factual information but emphasizing emotional or non-emotional goals. Findings showed that health messages that emphasized emotional goals, but not those that emphasized future-oriented or neutral goals, were better remembered, were evaluated more positively and led to greater behavioral changes among older adults, but not younger adults. These findings suggest that health messages targeting older adults may be more effective if they are framed in ways that emphasize love and caring.

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

10 CFR 54.37 - Additional records and recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... identified that would have been subject to an aging management review or evaluation of time-limited aging analyses in accordance with § 54.21. This FSAR update must describe how the effects of aging will be...

75 FR 79386 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-20

... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Hormone Therapy and Cognitive Aging. Date: January 11, 2011. Time: 11 a.m. to 12 p.m. Agenda: To review and evaluate...

The Effect of Implied Performer Age and Group Membership on Evaluations of Music Performances

ERIC Educational Resources Information Center

Harrington, Ann M.

2018-01-01

This study examined the effects of implied performer age and group membership on listeners' evaluations of music performances. Undergraduate music majors (n = 23), nonmusic majors (n = 17), and members of a New Horizons ensemble (n = 16) were presented with six 30-second excerpts of concert band performances. Excerpts were presented to all…

Evaluation of tropically-adapted straightbred and crossbred beef cattle: Heifer age and size at first conception and characteristics of their first calves

USDA-ARS?s Scientific Manuscript database

The objectives of this work were to estimate genetic effects for age and size at estimated time of first conception, and temperament in straightbred and crossbred heifers (n = 554) produced from Romosinuano, Brahman, and Angus cattle, and to evaluate first parturition performance of heifers, includi...

Factors Affecting the Mental Development of Very Low Birthweight Infants: An Evaluation Based Primarily on Covariance Structure Analysis.

ERIC Educational Resources Information Center

Honjo, Shuji; And Others

1998-01-01

Evaluated statistically the effect of intranatal and early postnatal period factors on mental development of very low-birth-weight infants. Covariance structure analysis revealed direct influence of birth weight and gestational age in weeks on mental development at age 1, and of opthalmological aberrations and respirator disorder on mental…

Evaluation of a Short-term, Cognitive-Behavioral Intervention for Primary Age Children with Anger-Related Difficulties

ERIC Educational Resources Information Center

Cole, Rachel L.; Treadwell, Susanne; Dosani, Sima; Frederickson, Norah

2013-01-01

This study evaluated the school-based short-term, cognitive-behavioral group anger management programme, "Learning How to Deal with our Angry Feelings" (Southampton Psychology Service, 2003). Thirteen groups of children aged 7- to 11-years-old were randomly allocated to two different cohorts: One cohort ("n"?=?35) first…

Air displacement plethysmography, dual-energy x-ray absorptiometry, and total body water to evaluate body composition in preschool-age children

USDA-ARS?s Scientific Manuscript database

Anthropometrics and body mass index are only proxies in the evaluation of adiposity in the pediatric population. Air displacement plethysmography technology was not available for children aged 6 months to 9 years until recently. Our study was designed to test the precision of air displacement plethy...

Attitudes toward Younger and Older Adults: The German Aging Semantic Differential

ERIC Educational Resources Information Center

Gluth, Sebastian; Ebner, Natalie C.; Schmiedek, Florian

2010-01-01

The present study used the German Aging Semantic Differential (ASD) to assess attitudes toward younger and older adults in a heterogeneous sample of n = 151 younger and n = 143 older adults. The questionnaire was administered in two versions, one referring to the evaluation of younger adults, the other to the evaluation of older adults.…

Development and Pilot Evaluation of a Psychosocial Intervention Program for Patients with Age-Related Macular Degeneration

ERIC Educational Resources Information Center

Birk, Tanja; Hickl, Susanne; Wahl, Hans-Werner; Miller, Daniel; Kammerer, Annette; Holz, Frank; Becker, Stefanie; Volcker, Hans E.

2004-01-01

Purpose: The psychosocial needs of patients suffering from severe visual loss associated with advanced age-related macular degeneration (ARMD) are generally ignored in the clinical routine. The aim of this study was to develop and evaluate a psychosocial intervention program for ARMD patients. This intervention program was based on six modules…

Development and Evaluation of Nutrition Education Competencies and a Competency-Based Resource Guide for Preschool-Aged Children

ERIC Educational Resources Information Center

Scherr, Rachel E.; Reed, Heather; Briggs, Marilyn; Zidenberg-Cherr, Sheri

2011-01-01

Purpose/Objectives: The purpose of this research was to develop and evaluate nutrition education competencies and a competency-based resource guide, Connecting the Dots...Healthy Foods, Healthy Choices, Healthy Kids (CTD), for preschool-aged children in California. Methods: Nutrition education experts and California Department of Education staff…

The Impact of Experienced Emotion on Evaluative Judgments: The Effects of Age and Emotion Regulation Style

PubMed Central

Hess, Thomas M.; Beale, Karen S.; Miles, Amanda

2012-01-01

Adults aged from 24 to 79 were exposed to four commercial advertisements within the context of television programs designed to induce either a positive or negative mood. Although age was associated with memory for the content of the commercials, it did not moderate the impact of mood on evaluations of the advertized products. Instead, participants who reported engaging in expressive suppression as a common emotion regulation strategy were more likely to make evaluations that were biased by moods than those individuals who reported low use of this strategy. The results suggest that the maintenance of emotion regulation ability in later adulthood may help people control certain affective influences on thought. PMID:20694860

Evaluation of Ultrasonic and Thermal Nondestructive Evaluation for the Characterization of Aging Degradation in Braided Composite Materials

NASA Technical Reports Server (NTRS)

Martin, Richard E.

2010-01-01

This paper examines the ability of traditional nondestructive evaluation (NDE) techniques to measure the degradation of braided polymer composite materials subjected to thermal-humidity cycling to simulate aging. A series of braided composite coupons were examined using immersion ultrasonic and pulsed thermography techniques in the as received condition. These same specimens were then examined following extended thermal-humidity cycling. Results of this examination did not show a significant change in the resulting (NDE) signals.

Comparison of developmental/intellectual changes between autistic disorder and pervasive developmental disorder not otherwise specified in preschool years.

PubMed

Takeda, Toshinobu; Koyama, Tomonori; Kurita, Hiroshi

2007-12-01

This study is the first to compare the change in developmental quotient (DQ) or IQ between autistic disorder (AD) and pervasive developmental disorder not otherwise specified (PDDNOS) in preschool years. Forty-nine AD children and 77 PDDNOS children were evaluated at age 2 and at age > or =5. The AD children were significantly lower in DQ/IQ at initial evaluation and outcome evaluation (also with initial DQ being controlled for) than the PDDNOS children.

Cognitive Changes Across the Menopause Transition: A Longitudinal Evaluation of the Impact of Age and Ovarian Status on Spatial Memory

PubMed Central

Koebele, Stephanie V.; Mennenga, Sarah E.; Hiroi, Ryoko; Quihuis, Alicia M.; Hewitt, Lauren T.; Poisson, Mallori L.; George, Christina; Mayer, Loretta P.; Dyer, Cheryl A.; Aiken, Leona S.; Demers, Laurence M.; Carson, Catherine; Bimonte-Nelson, Heather A.

2017-01-01

Cognitive changes that occur during mid-life and beyond are linked to both aging and the menopause transition. Studies in women suggest that the age at menopause onset can impact cognitive status later in life; yet, little is known about memory changes that occur during the transitional period to the post-menopausal state. The 4-vinylcyclohexene diepoxide (VCD) model simulates transitional menopause in rodents by depleting the immature ovarian follicle reserve and allowing animals to retain their follicle-deplete ovarian tissue, resulting in a profile similar to the majority of perimenopausal women. Here, Vehicle or VCD treatment was administered to ovary-intact adult and middle-aged Fischer-344 rats to assess the trajectory of cognitive change across time with normal aging and aging with transitional menopause via VCD-induced follicular depletion, as well as to evaluate whether age at the onset of follicular depletion plays a role in cognitive outcomes. Animals experiencing the onset of menopause at a younger age exhibited impaired spatial memory early in the transition to a follicle-deplete state. Additionally, at the mid- and post- follicular depletion time points, VCD-induced follicular depletion amplified an age effect on memory. Overall, these findings suggest that the age at the onset of menopause is a critical parameter to consider when evaluating learning and memory across the transition to reproductive senescence. From a translational perspective, this study illustrates how age at menopause onset might impact cognition in menopausal women, and provides insight into time points to explore for the window of opportunity for hormone therapy during the menopause transition period. Hormone therapy during this critical juncture might be especially efficacious at attenuating age- and menopause- related cognitive decline, producing healthy brain aging profiles in women who retain their ovaries throughout their lifespan. PMID:27793768

Cognitive changes across the menopause transition: A longitudinal evaluation of the impact of age and ovarian status on spatial memory.

PubMed

Koebele, Stephanie V; Mennenga, Sarah E; Hiroi, Ryoko; Quihuis, Alicia M; Hewitt, Lauren T; Poisson, Mallori L; George, Christina; Mayer, Loretta P; Dyer, Cheryl A; Aiken, Leona S; Demers, Laurence M; Carson, Catherine; Bimonte-Nelson, Heather A

2017-01-01

Cognitive changes that occur during mid-life and beyond are linked to both aging and the menopause transition. Studies in women suggest that the age at menopause onset can impact cognitive status later in life; yet, little is known about memory changes that occur during the transitional period to the postmenopausal state. The 4-vinylcyclohexene diepoxide (VCD) model simulates transitional menopause in rodents by depleting the immature ovarian follicle reserve and allowing animals to retain their follicle-deplete ovarian tissue, resulting in a profile similar to the majority of perimenopausal women. Here, Vehicle or VCD treatment was administered to ovary-intact adult and middle-aged Fischer-344 rats to assess the trajectory of cognitive change across time with normal aging and aging with transitional menopause via VCD-induced follicular depletion, as well as to evaluate whether age at the onset of follicular depletion plays a role in cognitive outcomes. Animals experiencing the onset of menopause at a younger age exhibited impaired spatial memory early in the transition to a follicle-deplete state. Additionally, at the mid- and post- follicular depletion time points, VCD-induced follicular depletion amplified an age effect on memory. Overall, these findings suggest that age at the onset of menopause is a critical parameter to consider when evaluating learning and memory across the transition to reproductive senescence. From a translational perspective, this study illustrates how age at menopause onset might impact cognition in menopausal women, and provides insight into time points to explore for the window of opportunity for hormone therapy during the menopause transition period. Hormone therapy during this critical juncture might be especially efficacious at attenuating age- and menopause- related cognitive decline, producing healthy brain aging profiles in women who retain their ovaries throughout their lifespan. Copyright © 2016 Elsevier Inc. All rights reserved.

Development of the Mini-Assisting Hand Assessment: evidence for content and internal scale validity.

PubMed

Greaves, Susan; Imms, Christine; Dodd, Karen; Krumlinde-Sundholm, Lena

2013-11-01

To describe the development of the Mini-Assisting Hand Assessment (Mini-AHA) for children with signs of unilateral cerebral palsy (CP) aged 8 to 18 months, and evaluate aspects of content and internal scale validity. The ability of the video-recorded Mini-AHA play session to provoke bimanual performance in children with unilateral CP and typical development was evaluated. Original AHA test items were examined for their suitability for younger children and possible new items were generated. Data from 108 assessments of children with unilateral CP (86 children, 53 males, 33 females; mean age 13 mo, SD 3 mo, range 8-18 mo) were entered into a Rasch measurement model analysis to evaluate internal scale validity. A Spearman's correlation analysis explored the relationship between age and ability measures for children with unilateral CP. The frequency of maximum scores in 40 children with typical development (22 males, 18 females; mean age 12 mo, SD 3 mo) was examined. The Mini-AHA play session provoked bimanual responses in typically developing children 99% of the time. Person and item fit criteria established 20 items for the scale. The resultant unidimensional scale also demonstrated excellent discriminative features through high separation reliability. The item calibration values covered the range of person ability measures well. Age was not related to the ability measures for children with unilateral CP (rs =0.178). All children with typical development achieved maximum scores. Accumulated evidence shows that the Mini-AHA validly measures use of the affected hand during bimanual performance for children with unilateral CP aged 8 to 18 months. The Mini-AHA has the potential to be a useful assessment to evaluate functional hand use and the effects of intervention in an age group when potential for change is high. © 2013 Mac Keith Press.

Expected Prevalence From the Differential Diagnosis of Anterior Knee Pain in Adolescent Female Athletes During Preparticipation Screening

PubMed Central

Barber Foss, Kim D.; Myer, Gregory D.; Chen, Stephen S.; Hewett, Timothy E.

2012-01-01

Context Anterior knee pain is a common disorder in female athletes with an undefined cause. The relative prevalence of specific patellofemoral disorders associated with anterior knee pain in adolescent females remains undetermined. Objective To determine the prevalence of specific patellofemoral disorders obtained using the differential diagnosis of anterior knee pain in adolescent female athletes during preparticipation screening. Design Descriptive epidemiology study. Setting Preparticipation screening evaluations at a county public school district in Kentucky. Patients or Other Participants A total of 419 unique middle and high school–aged female athletes. Main Outcome Measure(s) Participants were evaluated by physicians for anterior knee pain over 3 consecutive basketball seasons. Given the longitudinal nature of this study, some participants were tested longitudinally over multiple years. Results Over the course of 3 basketball seasons, 688 patient evaluations were performed. Of these, 183 (26.6%) were positive for anterior knee pain. A statistically significant difference was noted in the prevalence of anterior knee pain by school level, with 34.4% (n = 67) in high school–aged athletes versus 23.5% (n = 116) in middle school–aged athletes (P < .05). In the 1376 knees evaluated, patellofemoral dysfunction was the most common diagnosis, with an overall prevalence of 7.3% (n = 100). The only diagnosis shown to be statistically different between age levels was Sinding-Larsen-Johansson disease or patellar tendinopathy, with 38 cases (9.7%) in high school–aged and 31 (3.1%) in middle school–aged athletes (P < .05). Conclusions Anterior knee pain was present in 26.6% of the adolescent female athletes screened over 3 years. Symptoms of anterior knee pain likely persist after middle school–aged onset and reach peak prevalence during the high school years. PMID:23068589

Beliefs about fact retrieval and inferential reasoning across the adult lifespan.

PubMed

Camp, C J; Pignatiello, M F

1988-01-01

This study deals with beliefs about question-answering processes involving "world knowledge" utilized by young, middle aged, and older adults. Questions intended to induce either fact retrieval or inferential reasoning were shown to younger (n = 37), middle aged (n = 37) and older (n = 37) adults in both a multiple choice and true/false format. Increasing age level was not related to decreased confidence in either fact retrieval or inferential reasoning. Global assessments about these question-answering processes involving "people in general" and self evaluations were taken from the same individuals. In contrast to personal confidence ratings, adults of all ages generally believed in declining fact retrieval abilities in old age. Inferential reasoning, however, often was believed to remain stable or even increase in ability level with increasing age. This was especially true in the assessments generated by older adults and in self evaluations. Thus, negative global beliefs about memory and aging may be present even when such global beliefs contradict item-specific judgments and personal beliefs about one's own cognition.

Evaluation of amino-acid racemization/epimerization dating using radiocarbon-dated fossil land snails

NASA Astrophysics Data System (ADS)

Goodfriend, Glenn A.

1987-08-01

The relation between age and amino-acid epimer ratios (alloisoleucine/isoleucine, A/I) of Holocene land snails was quantitatively evaluated through 14C and amino-acid analysis of 33 samples from fluvial and colluvial sediments and rodent middens in the Northern Negev Desert of Israel. A/I is strongly correlated with 14C ages in fluvial and rodent midden deposits (r = 0.95 and 0.94, respectively), permitting age estimates from A/I ratios with precisions of ±700 and ±660 yr. The correlation is weaker in colluvial deposits (r = 0.74), and age estimates from A/I ratios are correspondingly less precise (±1580 yr). This probably results from delayed burial, which exposes the shells to intense radiation on the desert surface. Because of the generally strong relation between age and A/I, amino-acid epimerization analysis of individual shells can be used to identify mixed-age deposits and to reconstruct species chronologies from mixed-age deposits.

Three-dimensional analysis of third molar development to estimate age of majority.

PubMed

Márquez-Ruiz, Ana Belén; Treviño-Tijerina, María Concepción; González-Herrera, Lucas; Sánchez, Belén; González-Ramírez, Amanda Rocío; Valenzuela, Aurora

2017-09-01

Third molars are one of the few biological markers available for age estimation in undocumented juveniles close the legal age of majority, assuming an age of 18years as the most frequent legal demarcation between child and adult status. To obtain more accurate visualization and evaluation of third molar mineralization patterns from computed tomography images, a new software application, DentaVol©, was developed. Third molar mineralization according to qualitative (Demirjian's maturational stage) and quantitative parameters (third molar volume) of dental development was assessed in multi-slice helical computed tomography images of both maxillary arches displayed by DentaVol© from 135 individuals (62 females and 73 males) aged between 14 and 23years. Intra- and inter-observer agreement values were remarkably high for both evaluation procedures and for all third molars. A linear correlation between third molar mineralization and chronological age was found, with third molar maturity occurring earlier in males than in females. Assessment of dental development with both procedures, by using DentaVol© software, can be considered a good indicator of age of majority (18years or older) in all third molars. Our results indicated that virtual computed tomography imaging can be considered a valid alternative to orthopantomography for evaluations of third molar mineralization, and therefore a complementary tool for determining the age of majority. Copyright © 2017 The Chartered Society of Forensic Sciences. Published by Elsevier B.V. All rights reserved.

Evaluating the Prediction of Maximal Heart Rate in Children and Adolescents

ERIC Educational Resources Information Center

Mahon, Anthony D.; Marjerrison, Andrea D.; Lee, Jonah D.; Woodruff, Megan E.; Hanna, Lauren E.

2010-01-01

In this study, we compared measured maximal heart rate (HRmax) to two different HRmax prediction equations [220-age and 208-0.7(age)] in 52 children ages 7-17 years. We determined the relationship of chronological age, maturational age, and resting HR to measured HRmax and assessed seated resting HR and HRmax during a graded exercise test.…

Aging gauge

DOEpatents

Betts, Robert E.; Crawford, John F.

1989-04-04

An aging gauge comprising a container having a fixed or a variable sized t opening with a cap which can be opened to control the sublimation rate of a thermally sublimational material contained within the container. In use, the aging gauge is stored with an item to determine total heat the item is subjected to and also the maximum temperature to which the item has been exposed. The aging gauge container contains a thermally sublimational material such as naphthalene or similar material which has a low sublimation rate over the temperature range from about 70.degree. F. to about 160.degree. F. The aging products determined by analyses of a like item aged along with the aging gauge for which the sublimation amount is determined is employed to establish a calibration curve for future aging evaluation. The aging gauge is provided with a means for determining the maximum temperature exposure (i.e., a thermally indicating material which gives an irreversible color change, Thermocolor pigment). Because of the relationship of doubling reaction rates for increases of 10.degree. C., equivalency of item used in accelerated aging evaluation can be obtained by referring to a calibration curve depicting storage temperature on the abscissa scale and multiplier on the ordinate scale.

Aging gauge

DOEpatents

Betts, Robert E.; Crawford, John F.

1989-01-01

An aging gauge comprising a container having a fixed or a variable sized t opening with a cap which can be opened to control the sublimation rate of a thermally sublimational material contained within the container. In use, the aging gauge is stored with an item to determine total heat the item is subjected to and also the maximum temperature to which the item has been exposed. The aging gauge container contains a thermally sublimational material such as naphthalene or similar material which has a low sublimation rate over the temperature range from about 70.degree. F. to about 160.degree. F. The aging products determined by analyses of a like item aged along with the aging gauge for which the sublimation amount is determined is employed to establish a calibration curve for future aging evaluation. The aging gauge is provided with a means for determining the maximum temperature exposure (i.e., a thermally indicating material which gives an irreversible color change, Thermocolor pigment). Because of the relationship of doubling reaction rates for increases of 10.degree. C., equivalency of item used in accelerated aging evaluation can be obtained by referring to a calibration curve depicting storage temperature on the abscissa scale and multiplier on the ordinate scale.

A novel quantitative methodology for age evaluation of the human corneal endothelium

NASA Astrophysics Data System (ADS)

Rannou, Klervi; Thuret, Gilles; Gain, Philippe; Pinoli, Jean-Charles; Gavet, Yann

2017-03-01

The human corneal endothelium regulates the cornea transparency. Its cells, that cannot regenerate after birth, form a tesselated mosaic with almost perfect hexagonal cells during childhood, becoming progressively bigger and less ordered during aging. This study included 50 patients (in 10 decades groups) and 10 specular microscopy observations per patient. Five different criteria were measured on the manually segmented cells: area and perimeter of the cells as well as reduced Minkowski functionals. All these criteria were used to assess the probability of age group membership. We demonstrated that the age evaluation is near the reality, although a high variability was observed for patients between 30 and 70 years old.

Age Effects on Trustworthiness Activation and Trust Biases in Face Perception.

PubMed

Cassidy, Brittany S; Boucher, Kathryn L; Lanie, Shelby T; Krendl, Anne C

2018-05-26

Older adults evaluate faces as being more trustworthy than do younger adults. The present work examined whether aging is associated with changes in the dynamic activation of trustworthiness categories toward faces, and if category activation relates to enhanced trust. Younger and older adults categorized faces as trustworthy or untrustworthy while computer mouse trajectories were recorded to measure dynamic category activation. Older, but not younger, adults had more dynamic category activation (i.e., trustworthy and untrustworthy) when they viewed untrustworthy versus trustworthy faces. This tendency predicted a bias (pronounced with age) toward evaluating faces as being trustworthy. A pronounced trust bias in aging may be related to greater dynamic activation of trustworthiness (versus untrustworthiness) when perceiving faces.

[Construction of a psychological aging scale for healthy people].

PubMed

Lin, Fei; Long, Yao; Zeng, Ni; Wu, Lei; Huang, Helang

2017-04-28

To construct a psychological aging scale, and to provide a tool and indexes for scientific evaluation on aging.
 Methods: The age-related psychological items were collected through literature screening and expert interview. The importance, feasibilityand the degree of authority for the psychological index system were graded by two rounds of Delphi method. Using analytic hierarchy process, the weight of dimensions and items were determined. The analysis for internal consistency reliability, correlation and exploratory factor was performed to evaluate the reliability and validity of the scales.
 Results: By two rounds of Delphi method, 17 experts offered the results as follows: the coefficient of expert authorities was 0.88±0.06, the coordination coefficients for the importance and feasibility in second round were 0.456 (P<0.01) and 0.666 (P<0.01), respectively. The consistency was good. The psychological aging scale for healthy people included 4 dimensions as follows: cognitive function, emotion, personality and motivation. The weight coefficients for the 4 dimensions were 0.338, 0.250, 0.166 and 0.258, respectively. The Cronbach's α coefficient for the scale was 0.822, the reliability was 0.817, the content validity index (CVI) was 0.847, and the cumulative contribution rate for the 5 factors was51.42%.
 Conclusion: The psychological aging scale is satisfied, which can provide reference for the evaluation for aging. The indicators were representative and well-recognized.

Age and Environmental Concern: A Multivariate Analysis.

ERIC Educational Resources Information Center

Buttel, Frederick H.

1979-01-01

This paper provides detailed evidence on the relationships among age, education, and environmental values. The relative strengths of association of age and education in predicting environmental attitudes are evaluated. Present and future generational politics of environmentalism are discussed. (Author/EB)

78 FR 20669 - National Institute on Aging; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-05

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Management of the Primate Aging Database Date: April 23, 2013. Time: 1:00 p.m. to 4:00 p.m. Agenda: To review and evaluate...

75 FR 67381 - National Institute on Aging; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-02

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel HIV, HAART and AGING. Date: November 23, 2010. Time: 1 p.m. to 5 p.m. Agenda: To review and evaluate grant applications...

78 FR 9708 - National Institute on Aging Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Comparative Physiology of Aging. Date: March 14, 2013. Time: 12:30 p.m. to 3:30 p.m. Agenda: To review and evaluate grant... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging...

Good Cop, Better Cop: Evaluation of a Geriatrics Training Program for Police.

PubMed

Brown, Rebecca T; Ahalt, Cyrus; Rivera, Josette; Stijacic Cenzer, Irena; Wilhelm, Angela; Williams, Brie A

2017-08-01

To develop, implement, and evaluate a training program in aging-related health for police officers. Cross-sectional. Crisis intervention training program for police officers in San Francisco. Police officers attending one of five 2-hour trainings (N = 143). A lecture on aging-related health conditions pertinent to police work followed by three experiential trainings on how it feels to be "old." Participants evaluated the quality of the training and the likelihood that they would apply new knowledge to their work and rated their knowledge using a retrospective pre-post evaluation. In open-ended responses, participants reported work-related changes they anticipated making in response to the training. All 143 participants completed the evaluation. Eighty-four percent reported interacting with older adults at least monthly; 45% reported daily interactions. Participants rated the training quality at 4.6/5 and the likelihood they would apply new knowledge to their work at 4.4/5. Retrospective pre-post knowledge scores increased for all domains, including how to identify aging-related health conditions that can affect safety during police interactions (2.9/5 to 4.2/5; P < .001). In open-ended responses, participants anticipated having more empathy for and awareness of aging-related conditions and greater ability to provide older adults with appropriate community referrals. A brief training in aging-related health significantly increased police officers' self-reported knowledge and skills. Clinicians have an important opportunity to help enhance safe and effective community policing for older adults. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics Society.

Sensory memory during physiological aging indexed by mismatch negativity (MMN).

PubMed

Ruzzoli, Manuela; Pirulli, Cornelia; Brignani, Debora; Maioli, Claudio; Miniussi, Carlo

2012-03-01

Physiological aging affects early sensory-perceptual processes. The aim of this experiment was to evaluate changes in auditory sensory memory in physiological aging using the Mismatch Negativity (MMN) paradigm as index. The MMN is a marker recorded through the electroencephalogram and is used to evaluate the integrity of the memory system. We adopted a new, faster paradigm to look for differences between 3 groups of subjects of different ages (young, middle age and older adults) as a function of short or long intervals between stimuli. We found that older adults did not show MMN at long interval condition and that the duration of MMN varied according to the participants' age. The current study provides electrophysiological evidence supporting the theory that the encoding of stimuli is preserved during normal aging, whereas the maintenance of sensory memory is impaired. Considering the advantage offered by the MMN paradigm used here, these data might be a useful reference point for the assessment of auditory sensory memory in pathological aging (e.g., in neurodegenerative diseases). Copyright © 2012 Elsevier Inc. All rights reserved.

Evaluation of the accuracy of Demirjian method for estimation of dental age among 6-12 years of children in Navi Mumbai: A radiographic study.

PubMed

Hegde, Rahul J; Khare, Sumedh Suhas; Saraf, Tanvi A; Trivedi, Sonal; Naidu, Sonal

2015-01-01

Dental formation is superior to eruption as a method of dental age (DA) assessment. Eruption is only a brief occurrence, whereas formation may be related at different chronologic age levels, thereby providing a precise index for determining DA. The study was designed to determine the nature of inter-relationship between chronologic and DA. Age estimation depending upon tooth formation was done by Demirjian method and accuracy of Demirjian method was also evaluated. The sample for the study consisted of 197 children of Navi Mumbai. Significant positive correlation was found between chronologic age and DA that is, (r = 0.995), (P < 0.0001) for boys and (r = 0.995), (P < 0.0001) for girls. When age estimation was done by Demirjian method, mean the difference between true age (chronologic age) and assessed (DA) was 2 days for boys and 37 days for girls. Demirjian method showed high accuracy when applied to Navi Mumbai (Maharashtra - India) population. Demirjian method showed high accuracy when applied to Navi Mumbai (Maharashtra - India) population.

Education and age affect skill acquisition and retention in lay rescuers after a European Resuscitation Council CPR/AED course.

PubMed

Papalexopoulou, Konstantina; Chalkias, Athanasios; Dontas, Ioannis; Pliatsika, Paraskevi; Giannakakos, Charalampos; Papapanagiotou, Panagiotis; Aggelina, Afroditi; Moumouris, Theodoros; Papadopoulos, Georgios; Xanthos, Theodoros

2014-01-01

To examine whether education and age affect skill acquisition and retention in lay rescuers after a European Resuscitation Council (ERC) CPR/AED course. Because of the importance of bystander CPR/AED skills in the setting of cardiac arrest, acquisition and retention of resuscitation skills has gained a great amount of interest. The ERC CPR/AED course format for written and practical evaluation was used. Eighty lay people were trained and evaluated at the end of the course, as well as at one, three, and six months. Retention of CPR/AED skills improved over time, recording the lowest practical scores at one month after initial training and the lowest written scores at initial training. In practical evaluation scores, when examined longitudinally, age presented a significant adverse effect and higher background education presented a non-significant positive effect. Moreover, regarding written evaluation scores, when examined longitudinally, education presented a significant positive effect while age did not significantly correlate with written scores. Education and age affected retention of CPR/AED skills in lay rescuers. Also, our results suggest that the ERC CPR/AED course format may be poorly designed to discriminate between participants with different levels of practical and written resuscitation skills and merit a thorough investigation in future studies. Copyright © 2014 Elsevier Inc. All rights reserved.

Age, BMI, and race are less important than random plasma glucose in identifying risk of glucose intolerance: the Screening for Impaired Glucose Tolerance Study (SIGT 5).

PubMed

Ziemer, David C; Kolm, Paul; Weintraub, William S; Vaccarino, Viola; Rhee, Mary K; Caudle, Jane M; Irving, Jade M; Koch, David D; Narayan, K M Venkat; Phillips, Lawrence S

2008-05-01

Age, BMI, and race/ethnicity are used in National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and American Diabetes Association (ADA) guidelines to prompt screening for pre-diabetes and diabetes, but cutoffs have not been evaluated rigorously. Random plasma glucose (RPG) was measured and 75-g oral glucose tolerance tests were performed in 1,139 individuals without known diabetes. Screening performance was assessed by logistic regression and area under the receiver operating characteristic curve (AROC). NIDDK/ADA indicators age >45 years and BMI >25 kg/m(2) provided significant detection of both diabetes and dysglycemia (both AROCs 0.63), but screening was better with continuous-variable models of age, BMI, and race and better still with models of age, BMI, race, sex, and family history (AROC 0.78 and 0.72). However, screening was even better with RPG alone (AROCs 0.81 and 0.72). RPG >125 mg/dl could be used to prompt further evaluation with an OGTT. Use of age, BMI, and race/ethnicity in guidelines for screening to detect diabetes and pre-diabetes may be less important than evaluation of RPG. RPG should be investigated further as a convenient, inexpensive screen with good predictive utility.

Recognition of battery aging variations for LiFePO4 batteries in 2nd use applications combining incremental capacity analysis and statistical approaches

NASA Astrophysics Data System (ADS)

Jiang, Yan; Jiang, Jiuchun; Zhang, Caiping; Zhang, Weige; Gao, Yang; Guo, Qipei

2017-08-01

To assess the economic benefits of battery reuse, the consistency and aging characteristics of a retired LiFePO4 battery pack are studied in this paper. The consistency of battery modules is analyzed from the perspective of the capacity and the internal resistance. Test results indicate that battery module parameter dispersion increases along with battery aging. However, battery modules with better capacity consistency doesn't ensure better resistance consistency. Then the aging characteristics of the battery pack are analyzed and the main results are as follow: (1) Weibull and normal distribution are feasible to fit the capacity and resistance distribution of battery modules respectively; (2) SOC imbalance is the dominating factor in the capacity fading process of the battery pack; (3) By employing the incremental capacity (IC) and IC peak area analysis, a consistency evaluation method representing the aging mechanism variations of the battery modules is proposed and then an accurate battery screening strategy is put forward. This study not only provides data support for evaluating economic benefits of retired batteries but also presents a method to recognize the battery aging variations, which is helpful for rapid evaluation and screening of retired batteries for 2nd use.

Metabolite concentrations in skeletal muscle of different aged rats submitted to hypoxia and pharmacological treatment with nicergoline.

PubMed

Pastoris, O; Foppa, P; Catapano, M; Dossena, M

1998-06-01

The energy metabolism of the gastrocnemius and soleus muscles in young-adult, mature, and senescent rats was evaluated after 72 h of continuous exposure to normobaric hypoxia or normoxia. The effects of treatment with the alpha-adrenergic antagonist nicergoline were also investigated. In the gastrocnemius muscle we evaluated the concentrations of some significative metabolites involved in anaerobic glycolysis and the Krebs' cycle, free amino acids related to the Krebs' cycle, ammonia, some energy mediators, and the energy store creatine phosphate. In the soleus muscle a selection of these was evaluated. In both muscles aging was similarly characterized by a decrease in muscular creatine phosphate concentration, while the energy mediators and the energy charge potential remained unchanged. Singly, some gastrocnemius muscle metabolites showed linear changes in their concentrations with aging, while for the soleus muscle the only linear change regarded glucose-6-phosphate. Continuous normobaric hypoxia induced greater changes at the age of 4 and 24 months than at 12 months. Chronic treatment with nicergoline modified the influence of hypoxic conditions on muscle metabolites concentrations only in some cases, regardless of the age of the animals. Further investigations are necessary before any firm conclusions can be drawn about the pharmacological activity of nicergoline on hypoxia in aged rats.

Evaluative Language Used by Mandarin-Chinese-Speaking Dyads in Personal Narratives: Age and Socioeconomic Differences

ERIC Educational Resources Information Center

Lai, Wen-Feng; Chen, Yen-Yu

2016-01-01

The aim of this study was to determine the effects of age and family socioeconomic status (SES) on the evaluative language performance of Mandarin-Chinese-speaking young children and their mothers. The participants were 65 mother-child dyads recruited in Taiwan. Thirty-four of these dyads were from middle-class families and 31 were from…

Promoting Positive Family Interactions: Evaluating a Free Early Childhood Book Distribution Program

ERIC Educational Resources Information Center

Funge, Simon P.; Sullivan, Dana J.; Tarter, Kirsten

2017-01-01

The Dolly Parton Imagination Library (DPIL) program encourages reading among families of preschool children by mailing age-appropriate books, once per month, until the child reaches the age of five. An evaluation of a DPIL program in a southern state in the U.S. was conducted to assess the impact on enrolled children. Focus groups were conducted…

Evaluation and management of urinary tract infections in the school-aged child.

PubMed

Stephens, G Marcus; Akers, Scott; Nguyen, Hoa; Woxland, Heidi

2015-03-01

The evaluation and management of urinary tract infection in the school-aged child is an important part of primary care in the ambulatory setting. In this article, the salient features of how this condition presents to the clinician, how it is properly diagnosed and treated, and follow-up care are reviewed. Copyright © 2015 Elsevier Inc. All rights reserved.

Red-cockaded woodpecker nest-cavity selection: relationships with cavity age and resin production

Treesearch

Richard N. Conner; Daniel Saenz; D. Craig Rudolph; William G. Ross; David L. Kulhavy

1998-01-01

The authors evaluated selection of nest sites by male red-cockaded woodpeckers (Picoides borealis) in Texas relative to the age of the cavity when only cavities excavated by the woodpeckers were available and when both naturally excavated cavities and artificial cavities were available. They also evaluated nest-cavity selection relative to the ability of naturally...

Application of multi-way analysis to UV-visible spectroscopy, gas chromatography and electronic nose data for wine ageing evaluation.

PubMed

Prieto, N; Rodriguez-Méndez, M L; Leardi, R; Oliveri, P; Hernando-Esquisabel, D; Iñiguez-Crespo, M; de Saja, J A

2012-03-16

In this study, a multi-way method (Tucker3) was applied to evaluate the performance of an electronic nose for following the ageing of red wines. The odour evaluation carried out with the electronic nose was combined with the quantitative analysis of volatile composition performed by GC-MS, and colour characterisation by UV-visible spectroscopy. Thanks to Tucker3, it was possible to understand connections among data obtained from these three different systems and to estimate the effect of different sources of variability on wine evaluation. In particular, the application of Tucker3 supplied a global visualisation of data structure, which was very informative to understand relationships between sensors responses and chemical composition of wines. The results obtained indicate that the analytical methods employed are useful tools to follow the wine ageing process, to differentiate wine samples according to ageing type (either in barrel or in stainless steel tanks with the addition of small oak wood pieces) and to the origin (French or American) of the oak wood. Finally, it was possible to designate the volatile compounds which play a major role in such a characterisation. Copyright © 2012 Elsevier B.V. All rights reserved.

Soft neurological signs in childhood by measurement of arm movements using acceleration and angular velocity sensors.

PubMed

Kaneko, Miki; Yamashita, Yushiro; Inomoto, Osamu; Iramina, Keiji

2015-10-12

Soft neurological signs (SNS) are evident in the motor performance of children and disappear as the child grows up. Therefore SNS are used as criteria for evaluating age-appropriate development of neurological function. The aim of this study was to quantify SNS during arm movement in childhood. In this study, we focused on pronation and supination, which are arm movements included in the SNS examination. Two hundred and twenty-three typically developing children aged 4-12 years (107 boys, 116 girls) and 18 adults aged 21-26 years (16 males, two females) participated in the experiment. To quantify SNS during pronation and supination, we calculated several evaluation index scores: bimanual symmetry, compliance, postural stability, motor speed and mirror movement. These index scores were evaluated using data obtained from sensors attached to the participants' hands and elbows. Each score increased as age increased. Results obtained using our system showed developmental changes that were consistent with criteria for SNS. We were able to successfully quantify SNS during pronation and supination. These results indicate that it may be possible to use our system as quantitative criteria for evaluating development of neurological function.

TracerLPM (Version 1): An Excel® workbook for interpreting groundwater age distributions from environmental tracer data

USGS Publications Warehouse

Jurgens, Bryant C.; Böhlke, J.K.; Eberts, Sandra M.

2012-01-01

TracerLPM is an interactive Excel® (2007 or later) workbook program for evaluating groundwater age distributions from environmental tracer data by using lumped parameter models (LPMs). Lumped parameter models are mathematical models of transport based on simplified aquifer geometry and flow configurations that account for effects of hydrodynamic dispersion or mixing within the aquifer, well bore, or discharge area. Five primary LPMs are included in the workbook: piston-flow model (PFM), exponential mixing model (EMM), exponential piston-flow model (EPM), partial exponential model (PEM), and dispersion model (DM). Binary mixing models (BMM) can be created by combining primary LPMs in various combinations. Travel time through the unsaturated zone can be included as an additional parameter. TracerLPM also allows users to enter age distributions determined from other methods, such as particle tracking results from numerical groundwater-flow models or from other LPMs not included in this program. Tracers of both young groundwater (anthropogenic atmospheric gases and isotopic substances indicating post-1940s recharge) and much older groundwater (carbon-14 and helium-4) can be interpreted simultaneously so that estimates of the groundwater age distribution for samples with a wide range of ages can be constrained. TracerLPM is organized to permit a comprehensive interpretive approach consisting of hydrogeologic conceptualization, visual examination of data and models, and best-fit parameter estimation. Groundwater age distributions can be evaluated by comparing measured and modeled tracer concentrations in two ways: (1) multiple tracers analyzed simultaneously can be evaluated against each other for concordance with modeled concentrations (tracer-tracer application) or (2) tracer time-series data can be evaluated for concordance with modeled trends (tracer-time application). Groundwater-age estimates can also be obtained for samples with a single tracer measurement at one point in time; however, prior knowledge of an appropriate LPM is required because the mean age is often non-unique. LPM output concentrations depend on model parameters and sample date. All of the LPMs have a parameter for mean age. The EPM, PEM, and DM have an additional parameter that characterizes the degree of age mixing in the sample. BMMs have a parameter for the fraction of the first component in the mixture. An LPM, together with its parameter values, provides a description of the age distribution or the fractional contribution of water for every age of recharge contained within a sample. For the PFM, the age distribution is a unit pulse at one distinct age. For the other LPMs, the age distribution can be much broader and span decades, centuries, millennia, or more. For a sample with a mixture of groundwater ages, the reported interpretation of tracer data includes the LPM name, the mean age, and the values of any other independent model parameters. TracerLPM also can be used for simulating the responses of wells, springs, streams, or other groundwater discharge receptors to nonpoint-source contaminants that are introduced in recharge, such as nitrate. This is done by combining an LPM or user-defined age distribution with information on contaminant loading at the water table. Information on historic contaminant loading can be used to help evaluate a model's ability to match real world conditions and understand observed contaminant trends, while information on future contaminant loading scenarios can be used to forecast potential contaminant trends.

Evaluating and Treating Transverse Myelitis

MedlinePlus

... myelopathy. The doctor may note the person’s age, gender, and ethnicity. Weak evidence shows age and gender may help to narrow down the cause of ... is not enough evidence to show if age, gender, or ethnicity can point to a definite cause. ...

Automatic measurement of skin textures of the dorsal hand in evaluating skin aging.

PubMed

Gao, Qian; Yu, Jiaming; Wang, Fang; Ge, Tiantian; Hu, Liwen; Liu, Yang

2013-05-01

Changes in skin textures have been used to evaluate skin aging in many studies. In our previous study, we built some skin texture parameters, which can be used to evaluate skin aging of human dorsal hand. However, it will take too much time and need to work arduously to get the information from digital skin image by manual work. So, we want to build a simple and effective method to automatically count some of those skin texture parameters by using digital image-processing technology. A total of 100 subjects aged 30 years and above were involved. Sun exposure history and demographic information were collected by using a questionnaire. The skin image of subjects' dorsal hand was obtained by using a portable skin detector. The number of grids, which is one of skin texture parameters built in our previous study, was measured manually and automatically. Automated image analysis program was developed by using Matlab 7.1 software. The number of grids counted automatically (NGA) was significantly correlated with the number of grids counted manually (NGM) (r = 0.9287, P < 0.0001). And in each age group, there were no significant differences between NGA and NGM. The NGA was negatively correlated with age and lifetime sun exposure, and decreased with increasing Beagley-Gibson score from 3 to 6. In addition, even after adjusting for NGA, the standard deviation of grid areas for each image was positively correlated with age, sun exposure, and Bealey-Gibson score. The method introduced in present study can be used to measure some skin aging parameters automatically and objectively. And it will save much time, reduce labor, and avoid measurement errors of deferent investigators when evaluating a great deal of skin images in a short time. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seibert, JA; Boone, JM

Purpose: Phantom development in medical physics plays an important role in radiation dose assessment and image quality evaluation, and this is especially true in the pediatric patient population. The purpose of this investigation was to establish the relationship between patient age and patient size, focusing on the abdomen-pelvis and head effective diameters, for patients ranging in age from newborn to 18 years. Methods: A dose reporting tool for computed tomography systems was installed at our institution to achieve compliance with state law commencing on July 1, 2012. The software records a number of patient-specific data, and also reports CT dosemore » metrics (CTDIvol and DLP) into the patients interpretive report. The database generated by the software was mined to determine patient effective diameter as a function of age for pediatric patients aged 0–18 years. CT protocols including abdomen-pelvis and routine head were evaluated, and specific to this study the patients age, gender and equivalent diameter were recorded. Results: Six age ranges were evaluated: A(0–3), B(4–6), C(7–9), D(10–12),E(13–15),F(16–18). For the torso in these groups based upon 694 patients, median effective diameters were 147, 167, 184, 214, 231, 246 mm, respectively. For the head (N=1833), median diameters were 143, 157, 162, 168, 174, and 174, respectively. Conclusion: A solid understanding of the approximate dimensions of pediatric patients as a function of age is useful in the development of age-based imaging protocols and dose assessments. CT dose-reporting tools generate a great deal of data with respect to body dimensions automatically. In this study, median equivalent diameters for the abdomen-pelvis and head of pediatric patients were evaluated. These data may prove useful in the development of both mathematical and physical phantoms for dosimetry and image quality assessment.« less

Cost-Effectiveness of Osteoporosis Screening Strategies for Men

PubMed Central

Nayak, Smita; Greenspan, Susan L.

2016-01-01

Osteoporosis affects many men, with significant morbidity and mortality. However, the best osteoporosis screening strategies for men are unknown. We developed an individual-level state-transition cost-effectiveness model with a lifetime time horizon to identify the cost-effectiveness of different osteoporosis screening strategies for U.S. men involving various screening tests (dual-energy x-ray absorptiometry (DXA); the Osteoporosis Self-Assessment Tool (OST); or a fracture risk assessment strategy using age, femoral neck bone mineral density (BMD), and Vertebral Fracture Assessment (VFA)); screening initiation ages (50, 60, 70, or 80); and repeat screening intervals (5 years or 10 years). In base-case analysis, no screening was a less effective option than all other strategies evaluated; furthermore, no screening was more expensive than all strategies that involved screening with DXA or the OST risk assessment instrument, and thus no screening was “dominated” by screening with DXA or OST at all evaluated screening initiation ages and repeat screening intervals. Screening strategies that most frequently appeared as most cost-effective in base-case analysis and one-way sensitivity analyses when assuming willingness-to-pay of $50,000/QALY or $100,000/QALY included screening initiation at age 50 with the fracture risk assessment strategy and repeat screening every 10 years; screening initiation at age 50 with fracture risk assessment and repeat screening every 5 years; and screening initiation at age 50 with DXA and repeat screening every 5 years. In conclusion, expansion of osteoporosis screening for U.S. men to initiate routine screening at age 50 or 60 would be expected to be effective and of good value for improving health outcomes. A fracture risk assessment strategy using variables of age, femoral neck BMD, and VFA is likely to be the most effective of the evaluated strategies within accepted cost-effectiveness parameters. DXA and OST are also reasonable screening options, albeit likely slightly less effective than the evaluated fracture risk assessment strategy. PMID:26751984

Aging in community nutrition, diet therapy, and nutrition and aging textbooks.

PubMed

O'Neill, Peggy Schafer; Wellman, Nancy S; Himburg, Susan P; Johnson, Paulette; Elfenbien, Pamela

2005-01-01

Using content analysis, this study evaluated the aging content and context in 11 nutrition sub-specialty textbooks: community nutrition (n = 3), diet therapy (n = 4), and nutrition and aging (n = 4). Pages with paragraphs on aging were identified in community nutrition and diet therapy textbooks, and 10% random samples of pages were evaluated in nutrition and aging textbooks. Paragraphs were assigned to one of four categories: gerontology, nutrition as primary, nutrition as secondary, or tertiary prevention. A total of 310 pages was qualitatively analyzed using NUD*IST 5 software and quantitatively with percentages. Only 7% of community nutrition and 2% of diet therapy pages were devoted to aging. There was little integration of aging beyond the chapters on aging. Community nutrition had the most gerontology (30%) and primary prevention (43%) content. Diet therapy and nutrition and aging had more secondary prevention (33% and 42%, respectively) and tertiary prevention (27% each) content. Some important databases and studies were absent. Of the 1,239 ageism words, 10% were positive, 53% neutral, and 36% negative. Photographs were generally positive. Women, but not minorities, reflected current older adult demographics. Future textbook editions should address aging more comprehensively and positively to better prepare dietitians for the job market. Recommendations for authors, course instructors, and publishers are given.

Quantitative evaluation of age-related decline in control of preprogramed movement

PubMed Central

Lee, Jongho; Kodama, Mitsuhiko; Kakei, Shinji; Masakado, Yoshihisa

2017-01-01

In this paper, we examined the age-related changes in control of preprogramed movement, with emphasis on its accuracy. Forty-nine healthy subjects participated in this study, and were divided into three groups depending on their ages: the young group (20–39 years) (n = 16), the middle-age group (40–59 years) (n = 16), and the elderly group (60–79 years) (n = 17). We asked the subjects to perform step-tracking movements of the wrist joint with a manipulandum, and recorded the movements. We evaluated the accuracy of control of preprogramed movement in the three groups in terms of the primary submovement, which was identified as the first segment of the step-tracking movement based on the bell-shaped velocity profile, and calculated the distance between the end position of the primary submovement and the target (i.e. error). The error in the young group was found to be significantly smaller than that in the middle-age and elderly groups, i.e., the error was larger for the higher age groups. These results suggest that young subjects have better control of preprogramed movement than middle-age or elderly subjects. Finally, we examined the temporal property of the primary submovement and its age-related changes. The duration of the primary submovement tended to be longer for the aged groups, although significance was reached only for the elderly group. In particular, the ratio of the duration of the primary submovement to total movement time tended to be lower for the aged groups, suggesting that the proportion of additional movements that are required to compensate for the incomplete control in the preprogramed movement, which are under feedback control, was higher for the aged groups. Consequently, our results indicate that the distance between the end point of the primary submovement and the target center (i.e. error) in the step-tracking movement is a useful parameter to evaluate the age-related changes in control of preprogramed movement. PMID:29186168

Quantitative evaluation of age-related decline in control of preprogramed movement.

PubMed

Shimoda, Naoshi; Lee, Jongho; Kodama, Mitsuhiko; Kakei, Shinji; Masakado, Yoshihisa

2017-01-01

In this paper, we examined the age-related changes in control of preprogramed movement, with emphasis on its accuracy. Forty-nine healthy subjects participated in this study, and were divided into three groups depending on their ages: the young group (20-39 years) (n = 16), the middle-age group (40-59 years) (n = 16), and the elderly group (60-79 years) (n = 17). We asked the subjects to perform step-tracking movements of the wrist joint with a manipulandum, and recorded the movements. We evaluated the accuracy of control of preprogramed movement in the three groups in terms of the primary submovement, which was identified as the first segment of the step-tracking movement based on the bell-shaped velocity profile, and calculated the distance between the end position of the primary submovement and the target (i.e. error). The error in the young group was found to be significantly smaller than that in the middle-age and elderly groups, i.e., the error was larger for the higher age groups. These results suggest that young subjects have better control of preprogramed movement than middle-age or elderly subjects. Finally, we examined the temporal property of the primary submovement and its age-related changes. The duration of the primary submovement tended to be longer for the aged groups, although significance was reached only for the elderly group. In particular, the ratio of the duration of the primary submovement to total movement time tended to be lower for the aged groups, suggesting that the proportion of additional movements that are required to compensate for the incomplete control in the preprogramed movement, which are under feedback control, was higher for the aged groups. Consequently, our results indicate that the distance between the end point of the primary submovement and the target center (i.e. error) in the step-tracking movement is a useful parameter to evaluate the age-related changes in control of preprogramed movement.

Evaluation of successful aging among older people in China: Results from China health and retirement longitudinal study.

PubMed

Liu, Huaqing; Byles, Julie E; Xu, Xiaoyue; Zhang, Min; Wu, Xuesen; Hall, John J

2017-08-01

China faces a "time-bomb" of the aging population. Successful aging has long been a goal in the field of gerontology. The present study aimed to evaluate successful aging among Chinese older adults. Data on a total of 7102 people in the China Health and Retirement Study aged ≥60 years were analyzed in the present study. Successful aging is defined by the model of Rowe and Kahn including the following five indicators: "no major diseases," "no disability," "high cognitive functioning," "high physical functioning" and "active engagement with life." Using logistic regression analysis, crude and adjusted odds ratios with 95% confidence intervals were calculated to evaluate the relationship between sociodemographic parameters and successful aging. The prevalence of successful aging was 13.2% among Chinese older people. The percentage of older people with the five indicators, "no major diseases," "no disability," "high cognitive functioning," "high physical functioning," and "active engagement with life" was 41.7%, 92.1%, 54.2%, 70.2% and 46.0%, respectively. Multiple logistic regression showed people who had received education of high/vocational school or above had significantly greater odds of successful aging compared with those with less than primary school education (P < 0.05). The effect of education to college level or above on cognitive functioning was 2.51-fold higher in women than men (P = 0.006). Older people from a non-agricultural Hukou had 1.85-fold higher odds of successful aging than those from an agricultural Hukou. Older people living in the central, northeast or western regions had lower odds of successful aging relative to those living in the east coast region (0.72, 0.72 and 0.56, respectively). The prevalence of successful aging is low among Chinese older people, and is affected by sociodemographic factors, such as education, Hukou and regions. Geriatr Gerontol Int 2017; 17: 1183-1190. © 2016 Japan Geriatrics Society.

Body mass index and physical fitness in Brazilian adolescents.

PubMed

Lopes, Vitor P; Malina, Robert M; Gomez-Campos, Rossana; Cossio-Bolaños, Marco; Arruda, Miguel de; Hobold, Edilson

2018-05-05

Evaluate the relationship between body mass index and physical fitness in a cross-sectional sample of Brazilian youth. Participants were 3849 adolescents (2027 girls) aged 10-17 years. Weight and height were measured; body mass index was calculated. Physical fitness was evaluated with a multistage 20m shuttle run (cardiovascular endurance), standing long jump (power), and push-ups (upper body strength). Participants were grouped by sex into four age groups: 10-11, 12-13, 14-15, and 16-17 years. Sex-specific ANOVA was used to evaluate differences in each physical fitness item among weight status categories by age group. Relationships between body mass index and each physical fitness item were evaluated with quadratic regression models by age group within each sex. The physical fitness of thin and normal youth was, with few exceptions, significantly better than the physical fitness of overweight and obese youth in each age group by sex. On the other hand, physical fitness performances did not consistently differ, on average, between thin and normal weight and between overweight and obese youths. Results of the quadratic regressions indicated a curvilinear (parabolic) relationship between body mass index and each physical fitness item in most age groups. Better performances were attained by adolescents in the mid-range of the body mass index distribution, while performances of youth at the low and high ends of the body mass index distribution were lower. Relationships between the body mass index and physical fitness were generally nonlinear (parabolic) in youth 10-17 years. Copyright © 2018 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

Adherence to oral contraception in women on Category X medications.

PubMed

Steinkellner, Amy; Chen, William; Denison, Shannon E

2010-10-01

Over 6% of women become pregnant when taking teratogenic medications, and contraceptive counseling appears to occur at suboptimal rates. Adherence to contraception is an important component in preventing unwanted pregnancy and has not been evaluated in this population. We undertook a pharmacy claims-based analysis to evaluate the degree to which women of childbearing age who receive Category X medications adhere to their oral contraception. We evaluated the prescription medication claims for over 6 million women, age 18-44 years, with prescription benefits administered by a pharmacy benefits manager. Women with 2 or more claims for a Category X medication and 2 or more claims for oral contraception were evaluated in further detail. Adherence to oral contraception was measured by analyzing pharmacy claims. Multivariable logistic regression was performed to identify factors associated with adherence. There were 146,758 women of childbearing age who received Category X medications, of which 26,136 also took oral contraceptive medication. Women who received Category X medications were prescribed oral contraception (18%) at rates similar to others of childbearing age (17%). Women prescribed both Category X and oral contraception demonstrated adherence similar to the overall population. Age, class of Category X medication, number of medications, prescriber's specialty, and ethnicity correlated with lower adherence rates. Despite added risk associated with unintended pregnancy, many women who receive Category X medications have refill patterns suggesting nonadherence to oral contraception. Compared with all women age 18-44 years, women receiving teratogenic medications do not have better adherence to oral contraception. Copyright © 2010 Elsevier Inc. All rights reserved.

Two-dimensional auto-correlation analysis and Fourier-transform analysis of second-harmonic-generation image for quantitative analysis of collagen fiber in human facial skin

NASA Astrophysics Data System (ADS)

Ogura, Yuki; Tanaka, Yuji; Hase, Eiji; Yamashita, Toyonobu; Yasui, Takeshi

2018-02-01

We compare two-dimensional auto-correlation (2D-AC) analysis and two-dimensional Fourier transform (2D-FT) for evaluation of age-dependent structural change of facial dermal collagen fibers caused by intrinsic aging and extrinsic photo-aging. The age-dependent structural change of collagen fibers for female subjects' cheek skin in their 20s, 40s, and 60s were more noticeably reflected in 2D-AC analysis than in 2D-FT analysis. Furthermore, 2D-AC analysis indicated significantly higher correlation with the skin elasticity measured by Cutometer® than 2D-AC analysis. 2D-AC analysis of SHG image has a high potential for quantitative evaluation of not only age-dependent structural change of collagen fibers but also skin elasticity.

Protection of alodine coatings from thermal aging by removable polymer coatings.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wagstaff, Brett R.; Bradshaw, Robert W.; Whinnery, LeRoy L., Jr.

2006-12-01

Removable polymer coatings were evaluated as a means to suppress dehydration of Alodine chromate conversion coatings during thermal aging and thereby retain the corrosion protection afforded by Alodine. Two types of polymer coatings were applied to Alodine-treated panels of aluminum alloys 7075-T73 and 6061-T6 that were subsequently aged for 15 to 50 hours at temperatures between 135 F to 200 F. The corrosion resistance of the thermally aged panels was evaluated, after stripping the polymer coatings, by exposure to a standard salt-fog corrosion test and the extent of pitting of the polymer-coated and untreated panels compared. Removable polymer coatings mitigatedmore » the loss of corrosion resistance due to thermal aging experienced by the untreated alloys. An epoxide coating was more effective than a fluorosilicone coating as a dehydration barrier.« less

Radiological pitfalls of age estimation in adopted children: a case report.

PubMed

Gibelli, D; De Angelis, D; Cattaneo, C

2015-04-01

Age estimation has a relevant importance in assessing adopted children, also in cases where the age of the minor seems unquestioned, since pathological conditions may radically alter bodily growth. This may lead to an incorrect age evaluation, with consequent social and psychological problems linked to an inadequate collocation in public school. This study aims at exposing a case report concerning age estimation for a newly adopted child from Cambodia; previous clinical documentation reported information suggesting possible malnutrition, which was verified by the observation of a general disalignment of bone and dental structures. This example shows the importance of a thorough forensic evaluation of adopted children from other countries in order to verify the possible environmental modification of physiological growth even where it seems not to be needed, and represents a caveat for clinical and social personnel dealing with adoption procedures.

Aging curve of neuromotor function by pronation and supination of forearms using three-dimensional wireless acceleration and angular velocity sensors.

PubMed

Kaneko, M; Okui, H; Hirakawa, G; Ishinishi, H; Katayama, Y; Iramina, K

2012-01-01

We have developed an evaluation system for pronation and supination of forearms. The motion of pronation and supination of the forearm is used as a diagnosis method of developmental disability, etc. However, this diagnosis method has a demerit in which diagnosis results between doctors are not consistent. It is hoped that a more quantitative and simple evaluation method is established. Moreover it is hoped a diagnostic criteria obtained from healthy subjects can be established to diagnose developmental disorder patients. We developed a simple and portable evaluation system for pronation and supination of forearms. Three-dimensional wireless acceleration and angular velocity sensors are used for this system. In this study, pronation and supination of forearms of 570 subjects (subjects aged 6-12, 21-100) were examined. We could obtain aging curves in the neuromotor function of pronation and supination. These aging curves obtained by our developed system, has the potential to become diagnostic criteria for a developmental disability, etc.

How long will my mouse live? Machine learning approaches for prediction of mouse life span.

PubMed

Swindell, William R; Harper, James M; Miller, Richard A

2008-09-01

Prediction of individual life span based on characteristics evaluated at middle-age represents a challenging objective for aging research. In this study, we used machine learning algorithms to construct models that predict life span in a stock of genetically heterogeneous mice. Life-span prediction accuracy of 22 algorithms was evaluated using a cross-validation approach, in which models were trained and tested with distinct subsets of data. Using a combination of body weight and T-cell subset measures evaluated before 2 years of age, we show that the life-span quartile to which an individual mouse belongs can be predicted with an accuracy of 35.3% (+/-0.10%). This result provides a new benchmark for the development of life-span-predictive models, but improvement can be expected through identification of new predictor variables and development of computational approaches. Future work in this direction can provide tools for aging research and will shed light on associations between phenotypic traits and longevity.

Evaluation of Cognitive Function in the Group Setting.

ERIC Educational Resources Information Center

Rizzolo, Peter J.; And Others

Prevalence rates of cognitive impairment in persons 75 to 85 years of age have been documented in the range of 10-15%, and exceeding 20% after age 85. A recent study has demonstrated even higher prevalence rates: 18.7% between the ages of 75-84 and 47% in persons over 85 years of age. Screening for dementia in persons 75 years of age and older…

How much related to skin wrinkles between facial and body site? Age-related changes in skin wrinkle on the knee assessed by skin bioengineering techniques.

PubMed

Yoo, M A; Seo, Y K; Shin, M K; Koh, J S

2016-02-01

Skin aging has been focused the wrinkle on the face than on the body, so most studies have been studied the change in Crow's feet for ages. Only little is known about the age-dependent changes of wrinkles on body sites. The aim of this study was to establish new grading criteria for severity of wrinkles on knees and to investigate the relationship of wrinkle severity with age- and site-dependent. The skin on the knee of 38 healthy Korean female volunteers, divided into two groups young and old, were photographed. Standard photograph for body wrinkle was established (grade 0~7), and then visual assessment, skin wrinkle, and skin elasticity were evaluated on Crow's feet and the knee. We examined for any significant differences and the correlation of skin aging parameters with age and two different sites. Skin wrinkle severity with standard photograph and wrinkle parameters (Ra, Rmax, Rz, and Rv) had a significantly positive correlation with age-dependent on the knee (P < 0.001). Also, skin elastic parameters (R2, R5, R6, R7, and Q1) showed a significant negative correlation with age on the knee (P < 0.001). Skin wrinkle severity with standard photograph was highly correlated with all skin wrinkle parameters and skin elastic parameters (R2, R5, R7, and Q1) on the knee (P < 0.001). In addition, all the skin aging parameters on the knee were significantly correlated with Crow's feet (P < 0.01). Skin aging on the knee had the same tendency as the Crow's feet. This study has shown the new grading criteria of wrinkles on the knee. Skin wrinkle and elasticity on the knee are age-dependent related and aging on the knee is highly related to Crow's feet. Those parameters are using a quantitative method to evaluate body aging. Also, the knee is considered that it could be a suitable site to evaluate body aging. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Detection and evaluation of DNA methylation markers found at SCGN and KLF14 loci to estimate human age.

PubMed

Alghanim, Hussain; Antunes, Joana; Silva, Deborah Soares Bispo Santos; Alho, Clarice Sampaio; Balamurugan, Kuppareddi; McCord, Bruce

2017-11-01

Recent developments in the analysis of epigenetic DNA methylation patterns have demonstrated that certain genetic loci show a linear correlation with chronological age. It is the goal of this study to identify a new set of epigenetic methylation markers for the forensic estimation of human age. A total number of 27 CpG sites at three genetic loci, SCGN, DLX5 and KLF14, were examined to evaluate the correlation of their methylation status with age. These sites were evaluated using 72 blood samples and 91 saliva samples collected from volunteers with ages ranging from 5 to 73 years. DNA was bisulfite modified followed by PCR amplification and pyrosequencing to determine the level of DNA methylation at each CpG site. In this study, certain CpG sites in SCGN and KLF14 loci showed methylation levels that were correlated with chronological age, however, the tested CpG sites in DLX5 did not show a correlation with age. Using a 52-saliva sample training set, two age-predictor models were developed by means of a multivariate linear regression analysis for age prediction. The two models performed similarly with a single-locus model explaining 85% of the age variance at a mean absolute deviation of 5.8 years and a dual-locus model explaining 84% of the age variance with a mean absolute deviation of 6.2 years. In the validation set, the mean absolute deviation was measured to be 8.0 years and 7.1 years for the single- and dual-locus model, respectively. Another age predictor model was also developed using a 40-blood sample training set that accounted for 71% of the age variance. This model gave a mean absolute deviation of 6.6 years for the training set and 10.3years for the validation set. The results indicate that specific CpGs in SCGN and KLF14 can be used as potential epigenetic markers to estimate age using saliva and blood specimens. These epigenetic markers could provide important information in cases where the determination of a suspect's age is critical in developing investigative leads. Copyright © 2017. Published by Elsevier B.V.

Disability Evaluation in Japan

PubMed Central

2009-01-01

To examine the current state and social ramifications of disability evaluation in Japan, public data from Annual Reports on Health and Welfare 1998-1999 were investigated. All data were analyzed based on the classification of disabilities and the effects of age-appropriate welfare services, which have been developed through a half-century of legislative efforts to support disability evaluation. These data suggest that disability evaluation, while essentially affected by age and impairment factors at a minimum, was impacted more by the assistive environment for disabilities. The assistive environment was found to be closely linked with the welfare support system related to a global assessment in the field of community-based rehabilitation. PMID:19503677

Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia

PubMed Central

Wahl, Devin; Coogan, Sean CP; Solon-Biet, Samantha M; de Cabo, Rafael; Haran, James B; Raubenheimer, David; Cogger, Victoria C; Mattson, Mark P; Simpson, Stephen J; Le Couteur, David G

2017-01-01

Evaluation of behavior and cognition in rodent models underpins mechanistic and interventional studies of brain aging and neurodegenerative diseases, especially dementia. Commonly used tests include Morris water maze, Barnes maze, object recognition, fear conditioning, radial arm water maze, and Y maze. Each of these tests reflects some aspects of human memory including episodic memory, recognition memory, semantic memory, spatial memory, and emotional memory. Although most interventional studies in rodent models of dementia have focused on pharmacological agents, there are an increasing number of studies that have evaluated nutritional interventions including caloric restriction, intermittent fasting, and manipulation of macronutrients. Dietary interventions have been shown to influence various cognitive and behavioral tests in rodents indicating that nutrition can influence brain aging and possibly neurodegeneration. PMID:28932108

Moral complexity in middle childhood: children's evaluations of necessary harm.

PubMed

Jambon, Marc; Smetana, Judith G

2014-01-01

We assessed 5- to 11-year-olds' (N = 76) judgments of straightforward moral transgressions (prototypical harm) as well as their evaluations of complex, hypothetical scenarios in which an actor transgresses in order to prevent injury (necessary harm). The nature of the actor's transgression (psychological or physical harm) varied across participants. Moral judgments and justifications, knowledge of the actor's psychological experience, and their associations were examined. At all ages, children negatively evaluated prototypical harm; judgments of necessary harm became increasingly more forgiving with age as justifications pertaining to the actor's harm decreased. References to the actor's positive actions and children's tendency to coordinate conflicting concerns increased with age, but only when evaluating psychological harm. Across conditions, older children viewed transgressors as holding increasingly more positive attitudes toward their own actions, and this was uniquely associated with more forgiving moral judgments and justifications of necessary but not prototypical harm. Findings are discussed in relation to the emergence of more flexible and nuanced moral evaluations during middle childhood. PsycINFO Database Record (c) 2014 APA, all rights reserved.

Identity consolidation in early adulthood: relations with ego-resiliency, the context of marriage, and personality change.

PubMed

Pals, J L

1999-04-01

Identity consolidation during early adulthood was conceptualized as a process of investing oneself in new adult roles, responsibilities, and contexts and evaluating one's ongoing experience in order to construct a coherent, grounded, and positive identity. The current study longitudinally examined (age 21 to age 27) the roles of ego-resiliency, an important personality resource, and marriage, an important identity context, in the process of identity consolidation as it unfolded in a cohort of women who experienced early adulthood during the early 1960s. Prototypes of identity in marriage were developed to reflect the different ways these women invested and evaluated their identities in the context of marriage. Results showed that ego-resiliency at age 21 and the experience of identity in marriage at age 27 were both related to identity consolidation at age 27, and findings also suggested that the relation of age 21 ego-resiliency to age 27 identity consolidation was mediated by identity in marriage. Finally, successful identity consolidation was associated with increasing ego-resiliency from age 21 to age 27. Discussion focuses on the interaction between personality and social context in the process of identity consolidation and the role of identity consolidation in personality change.

An evaluation of the use of pentosidine as a biomarker for ageing turtles

PubMed Central

Iverson, John B.; Stahl, Randal S.; Furcolow, Carol; Kraus, Fred

2017-01-01

Concentrations of the biomarker pentosidine have been shown to be useful measures of age for a number of avian and mammalian species. However, no study has examined its usefulness as an age marker in a long-lived ectotherm despite the fact that such a marker could prove useful in understanding age distributions of populations subject to conservation programmes. Therefore, we evaluated pentosidine concentrations in the interdigital webbing of 117 female yellow mud turtles (Kinosternon flavescens) at a 35 year study site in western Nebraska where nearly all turtles are of known age. Pentosidine concentrations were extraordinarily low and positively correlated with age in this turtle, but concentrations were too variable to permit precise estimates of age for turtles of unknown age. These results may reflect the remarkable physiological adaptations of this turtle to low temperatures and oxygen deprivation in a highly seasonal environment requiring prolonged hibernation. Whether pentosidine concentrations in other ectotherms occupying less seasonal environments would be more highly correlated with age remains to be determined. However, our results suggest that patterns of accumulation of pentosidine in ectotherms may be fundamentally different from those in endotherms. PMID:28149519

Dental anomalies and dental age assessment in treated children with acute lymphoblastic leukemia.

PubMed

Khojastepour, L; Zareifar, S; Ebrahimi, M

2014-01-01

This cross sectional study was performed to evaluate dental ages and incidence of dental anomalies in children treated for acute lymphoblastic leukemia (ALL). A total of 25 ALL patient who passed at least 2 years of chemotherapy and 25 healthy sex and age matched children were evaluated. Dental age as well as dental anomalies in shape, size, number, and structure was recorded based on their panoramic radiographies which were taken for dental purposes. The number of dental anomalies significantly increased in ALL treated children. Seven ALL cases (28%) in compression to only one (4%) in control group had at least one dental anomaly. However, there was neither statistically significant differences between the mean of dental (p=0.32) and chronologic age (p=0.12) in both groups, nor between dental age of cases and control group (p=0.62).The age at the onset of treatment as well as treatment durations has not affected dental age and the incidence of dental anomalies significantly (p<0.05). Chemotherapy in children results in emergence of dental anomaly. Dental age, maturity, and development process however seems to be independent from chemotherapy.

Effects of real-time thermal aging on graphite/polyimide composites

NASA Technical Reports Server (NTRS)

Haskins, J. F.; Kerr, J. R.

1985-01-01

As part of a program to evaluate high-temperature advanced composites for use on supersonic cruise transport aircraft, two graphite/polyimide composites have been aged at elevated temperatures for times up to 5.7 years. Work on the first, HT-S/710 graphite/polyimide, was started in 1974. Evaluation of the second polyimide, Celion 6000/LARC-160, began in 1980. Baseline properties are presented, including unnotched and notched tensile data as a function of temperature, compression, flexure, shear, and constant-amplitude fatigue data at R = 0.1 and R = -1. Tensile specimens were aged in ovens where pressure and aging temperatures were controlled for various times up to and including 50,000 hours. Changes in tensile strength were determined and plotted as a function of aging time. The HT-S/710 composite aged at 450 F and 550 F if compared to the Celion 6000/LARC-160 composite aged at 350 F and 450 F. After tensile testing, many of the thermal aging specimens were examined using a scanning electron microscope. Results of these studies are presented, and changes in properties and degradation mechanisms during high-temperature aging are discussed and illustrated using metallographic techniques.

Radiologic assessment of third molar tooth and spheno-occipital synchondrosis for age estimation: a multiple regression analysis study.

PubMed

Demirturk Kocasarac, Husniye; Sinanoglu, Alper; Noujeim, Marcel; Helvacioglu Yigit, Dilek; Baydemir, Canan

2016-05-01

For forensic age estimation, radiographic assessment of third molar mineralization is important between 14 and 21 years which coincides with the legal age in most countries. The spheno-occipital synchondrosis (SOS) is an important growth site during development, and its use for age estimation is beneficial when combined with other markers. In this study, we aimed to develop a regression model to estimate and narrow the age range based on the radiologic assessment of third molar and SOS in a Turkish subpopulation. Panoramic radiographs and cone beam CT scans of 349 subjects (182 males, 167 females) with age between 8 and 25 were evaluated. Four-stage system was used to evaluate the fusion degree of SOS, and Demirjian's eight stages of development for calcification for third molars. The Pearson correlation indicated a strong positive relationship between age and third molar calcification for both sexes (r = 0.850 for females, r = 0.839 for males, P < 0.001) and also between age and SOS fusion for females (r = 0.814), but a moderate relationship was found for males (r = 0.599), P < 0.001). Based on the results obtained, an age determination formula using these scores was established.

Computerized Bone Age Estimation Using Deep Learning Based Program: Evaluation of the Accuracy and Efficiency.

PubMed

Kim, Jeong Rye; Shim, Woo Hyun; Yoon, Hee Mang; Hong, Sang Hyup; Lee, Jin Seong; Cho, Young Ah; Kim, Sangki

2017-12-01

The purpose of this study is to evaluate the accuracy and efficiency of a new automatic software system for bone age assessment and to validate its feasibility in clinical practice. A Greulich-Pyle method-based deep-learning technique was used to develop the automatic software system for bone age determination. Using this software, bone age was estimated from left-hand radiographs of 200 patients (3-17 years old) using first-rank bone age (software only), computer-assisted bone age (two radiologists with software assistance), and Greulich-Pyle atlas-assisted bone age (two radiologists with Greulich-Pyle atlas assistance only). The reference bone age was determined by the consensus of two experienced radiologists. First-rank bone ages determined by the automatic software system showed a 69.5% concordance rate and significant correlations with the reference bone age (r = 0.992; p < 0.001). Concordance rates increased with the use of the automatic software system for both reviewer 1 (63.0% for Greulich-Pyle atlas-assisted bone age vs 72.5% for computer-assisted bone age) and reviewer 2 (49.5% for Greulich-Pyle atlas-assisted bone age vs 57.5% for computer-assisted bone age). Reading times were reduced by 18.0% and 40.0% for reviewers 1 and 2, respectively. Automatic software system showed reliably accurate bone age estimations and appeared to enhance efficiency by reducing reading times without compromising the diagnostic accuracy.

Development of laboratory oxidative aging procedures for asphalt cements and asphalt mixtures.

DOT National Transportation Integrated Search

1986-12-01

An evaluation of an oxidative aging procedure for asphalt materials is described. Test results and the effectiveness of the aging device used are presented. The study was performed by Oregon State University and the Oregon Department of Transportatio...

Experimental evaluation of the Battelle accelerated test design for the solar array at Mead, Nebraska

NASA Technical Reports Server (NTRS)

Frickland, P. O.; Repar, J.

1982-01-01

A previously developed test design for accelerated aging of photovoltaic modules was experimentally evaluated. The studies included a review of relevant field experience, environmental chamber cycling of full size modules, and electrical and physical evaluation of the effects of accelerated aging during and after the tests. The test results indicated that thermally induced fatigue of the interconnects was the primary mode of module failure as measured by normalized power output. No chemical change in the silicone encapsulant was detectable after 360 test cycles.

Dental Implants in an Aged Population: Evaluation of Periodontal Health, Bone Loss, Implant Survival, and Quality of Life.

PubMed

Becker, William; Hujoel, Philippe; Becker, Burton E; Wohrle, Peter

2016-06-01

To evaluate aged partially and fully edentulous patients who received dental implants and were maintained over time. Further, to determine how the partially and edentulous ageing populations (65 and above) with dental implants maintain bone levels, proper oral hygiene, and perceive benefits of dental implants. Since 1995, patients receiving dental implants have been prospectively entered into an Access-based computerized program (Triton Tacking System). Patient demographics (age, sex), bone quality, quantity, implant location, and type of surgery have been continuously entered into the database. The database was queried for patients receiving implants (first stage) between 66 and 93 years of age. Thirty-one patients were within this age group. Twenty-five patients returned to the clinic for periodontal and dental implant evaluation. The Periodontal Index was used to evaluate selected teeth in terms of probing depth, bleeding on probing, plaque accumulation, and mobility. Using NIH Image J, radiographs taken at second stage and last examination were measured for changes in interproximal bone levels. Once identified, each patient anomalously filled out an abbreviated quality of health life form. Due to small sample size, descriptive statistics were used to compare clinical findings. Fifteen males ranging from 78 to 84 (mean age 84 years) years and 16 females from 66 to 93 (mean age 83 years) (age range 66-93) were contacted by phone or mail and asked to return to our office for a re-examination. For this group, the first dental implants were placed in 1996 (n = initial two implants) and continuously recorded through 2013 (n = last seven implants). Thirty-one patients received a total of 84 implants. Two patients were edentulous, and the remaining were partially edentulous. Four implants were lost. Between implant placement and 6- to 7-year interval, 13 patients with 40 implants had a cumulative survival rate of 94.6%. Of the original group (n = 33), three were deceased, two were in nursing homes, and three could not be located. Aged patients receiving dental implants had excellent implant survival rates, low periodontal disease index scores with minimal changes in interproximal bone levels. Results from this study indicate that patients with advanced age, in reasonably good health, have excellent implant survival rates, excellent quality of life scores, and can be maintained in good oral health. © 2015 Wiley Periodicals, Inc.

Auditory Brainstem Responses from Children Three Months to Three Years of Age: Normal Patterns of Response II.

ERIC Educational Resources Information Center

Gorga, Michael P.; And Others

1989-01-01

Auditory brainstem responses (ABR) were measured in 535 children from 3 months to 3 years of age. Results suggested that changes in wave V latency with age are due to central (neural) factors and that age-appropriate norms should be used in evaluations of ABR latencies in children. (Author/DB)

English Language Learners and Kindergarten Entry Age: Achievement and Social-Emotional Effects

ERIC Educational Resources Information Center

Gottfried, Michael; Le, Vi-Nhuan; Datar, Ashlesha

2016-01-01

In evaluating the role of kindergarten entry age, previous researchers have not examined the entry-age effects for English language learners (ELL). Additionally, little work has assessed the role of entry age on both achievement and social-emotional outcomes. This study is the first to do both simultaneously. The authors used data from a…

Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages

EPA Science Inventory

Predicting age-specific metabolism is important for evaluating age-related drug and chemical sensitivity. Multiple cytochrome P450s and carboxylesterase enzymes are responsible for human pyrethroid metabolism. Complete ontogeny data for each enzyme are needed to support in vitro ...

20 CFR 404.1563 - Your age as a vocational factor.

Code of Federal Regulations, 2013 CFR

2013-04-01

... evaluating the overall impact of all the factors of your case. (c) Younger person. If you are a younger... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Your age as a vocational factor. 404.1563... age as a vocational factor. (a) General. “Age” means your chronological age. When we decide whether...

The Relationship between Age and IQ in Adults with Williams Syndrome

ERIC Educational Resources Information Center

Searcy, Yvonne M.; Lincoln, Alan J.; Rose, Fredric E.; Klima, Edward S.; Bavar, Nasim; Korenberg, Julie R.

2004-01-01

The relationship between age and IQ was evaluated in a cross-sectional sample of 80 individuals with Williams syndrome (17 to 52 years). The relationship between age and WAIS-R subtest scores was such that increases and decreases in raw scores occurred at a rate sufficient to maintain stability of age-corrected scaled scores, indicating a…

Optimal dietary energy and protein for gilt development: Age at puberty, ovulation rate, and reproductive tract traits

USDA-ARS?s Scientific Manuscript database

The effect of feeding different lysine and metabolizable energy (ME) levels to 1221 crossbred Large White × Landrace developing gilts housed in groups from 100 d of age until slaughter (approximately 260 d of age) on age at puberty and reproductive tract measurements were evaluated. Gilts were rando...

[Relevant Factors on Cognitive Evaluation of the Portuguese Population].

PubMed

Oliveira, Catarina Resende; Mota-Pinto, Anabela; Rodrigues, Vítor; Alves, Catarina

2017-04-28

Aging is an inevitable process that has a social impact in the forecoming decades, and it will present a great challenge regarding public health. An efficient health system requires a reflection on the preventive measures to be implemented. The study population comprised a total number of 2672 individuals of both genders, aged 55 years and over, residents in continental Portugal, to whom a questionnaire was applied that included the following sections: Social network; Locomotion; Physical autonomy; Instrumental autonomy; Cognitive assessment; Physical activity. The study of aging in the Portuguese population found that physical autonomy for tasks related to daily life are associated with better cognitive evaluation. A statistically significant association was found between performance in cognitive assessment and gender, age, schooling, the fact of living alone, the number of hours being alone, autonomy to walk in the street, washing, dressing, eating, preparing meals, doing shopping, managing money and taking medications and washer / treat clothing. Cognitive evaluation is negatively influenced by the number of hours that an individual is alone. Activities of daily life must be valued, since they require the ability to plan and carry out tasks and their preservation is a key component in successful aging.

[Sero-epidemiology of VZV infection in Italy: impact evaluation of extensive vaccination].

PubMed

Gabutti, Giovanni; Rota, Maria Cristina; De Donno, Antonella; Guido, Marcello; Bella, Antonino; Idolo, Adele; Lupi, Silvia; Brignole, Giordana

2014-01-01

Eight Italian Regions have begun offering vaccination against varicella to children aged 13-15 months, with a second dose at 5-6 years of age. A serosurvey was conducted to evaluate the impact of extensive vaccination in these "pilot" Regions. Samples were collected in compliance with current legislation and after the approval of the Ethics Committee. The qualitative and quantitative determination of antibodies (IgG) against varicella was performed using an ELISA assay with high sensitivity and specificity. 1,470 samples were analyzed. After the decrease of seropositivity associated with the decay of passively acquired antibody titer, there was a progressive increase of seroprevalence in the other age groups. The comparison with what was recorded in two studies conducted with similar assays in the periods 1996/97 and 2003/04, showed a significant increase in seroprevalence following extensive immunization, particularly in the age classes 1 year, 2-4 years and 5-9 years. The proportion of seropositivity in the age classes 1 year and 2-4 years has more than doubled. Seroepidemiological studies are a useful tool to evaluate the distribution of susceptible individuals in the population. This study highlighted the impact of extensive vaccination against varicella in eight "pilot" Regions.

Is lack of sleep capable of inducing DNA damage in aged skin?

PubMed

Kahan, V; Ribeiro, D A; Egydio, F; Barros, L A; Tomimori, J; Tufik, S; Andersen, M L

2014-01-01

Skin naturally changes with age, becoming more fragile. Various stimuli can alter skin integrity. The aim of this study was to evaluate whether sleep deprivation affects the integrity of DNA in skin and exacerbates the effects of aging. Fifteen-month old female Hairless mice underwent 72 h of paradoxical sleep deprivation or 15 days of chronic sleep restriction. Punch biopsies of the skin were taken to evaluate DNA damage by single cell gel (comet) assay. Neither paradoxical sleep deprivation nor sleep restriction increased genetic damage, measured by tail movement and tail intensity values. Taken together, the findings are consistent with the notion that aging overrides the effect of sleep loss on the genetic damage in elderly mice. © 2014 S. Karger AG, Basel.

Development of Evaluation Methods for Lower Limb Function between Aged and Young Using Principal Component Analysis

NASA Astrophysics Data System (ADS)

Nomoto, Yohei; Yamashita, Kazuhiko; Ohya, Tetsuya; Koyama, Hironori; Kawasumi, Masashi

There is the increasing concern of the society to prevent the fall of the aged. The improvement in aged people's the muscular strength of the lower-limb, postural control and walking ability are important for quality of life and fall prevention. The aim of this study was to develop multiple evaluation methods in order to advise for improvement and maintenance of lower limb function between aged and young. The subjects were 16 healthy young volunteers (mean ± S.D: 19.9 ± 0.6 years) and 10 healthy aged volunteers (mean ± S.D: 80.6 ± 6.1 years). Measurement items related to lower limb function were selected from the items which we have ever used. Selected measurement items of function of lower are distance of extroversion of the toe, angle of flexion of the toe, maximum width of step, knee elevation, moving distance of greater trochanter, walking balance, toe-gap force and rotation range of ankle joint. Measurement items summarized by the principal component analysis into lower ability evaluation methods including walking ability and muscle strength of lower limb and flexibility of ankle. The young group demonstrated the factor of 1.6 greater the assessment score of walking ability compared with the aged group. The young group demonstrated the factor of 1.4 greater the assessment score of muscle strength of lower limb compared with the aged group. The young group demonstrated the factor of 1.2 greater the assessment score of flexibility of ankle compared with the aged group. The results suggested that it was possible to assess the lower limb function of aged and young numerically and to advise on their foot function.

Age and education corrected older adult normative data for a short form version of the Financial Capacity Instrument.

PubMed

Gerstenecker, Adam; Eakin, Amanda; Triebel, Kristen; Martin, Roy; Swenson-Dravis, Dana; Petersen, Ronald C; Marson, Daniel

2016-06-01

Financial capacity is an instrumental activity of daily living (IADL) that comprises multiple abilities and is critical to independence and autonomy in older adults. Because of its cognitive complexity, financial capacity is often the first IADL to show decline in prodromal and clinical Alzheimer's disease and related disorders. Despite its importance, few standardized assessment measures of financial capacity exist and there is little, if any, normative data available to evaluate financial skills in the elderly. The Financial Capacity Instrument-Short Form (FCI-SF) is a brief measure of financial skills designed to evaluate financial skills in older adults with cognitive impairment. In the current study, we present age- and education-adjusted normative data for FCI-SF variables in a sample of 1344 cognitively normal, community-dwelling older adults participating in the Mayo Clinic Study of Aging (MCSA) in Olmsted County, Minnesota. Individual FCI-SF raw scores were first converted to age-corrected scaled scores based on position within a cumulative frequency distribution and then grouped within 4 empirically supported and overlapping age ranges. These age-corrected scaled scores were then converted to age- and education-corrected scaled scores using the same methodology. This study has the potential to substantially enhance financial capacity evaluations of older adults through the introduction of age- and education-corrected normative data for the FCI-SF by allowing clinicians to: (a) compare an individual's performance to that of a sample of similar age and education peers, (b) interpret various aspects of financial capacity relative to a normative sample, and (c) make comparisons between these aspects. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Effects of aging and involuntary capture of attention on event-related potentials associated with the processing of and the response to a target stimulus

PubMed Central

Cid-Fernández, Susana; Lindín, Mónica; Díaz, Fernando

2014-01-01

The main aim of the present study was to assess whether aging modulates the effects of involuntary capture of attention by novel stimuli on performance, and on event-related potentials (ERPs) associated with target processing (N2b and P3b) and subsequent response processes (stimulus-locked Lateralized Readiness Potential -sLRP- and response-locked Lateralized Readiness Potential -rLRP-). An auditory-visual distraction-attention task was performed by 77 healthy participants, divided into three age groups (Young: 21–29, Middle-aged: 51–64, Old: 65–84 years old). Participants were asked to attend to visual stimuli and to ignore auditory stimuli. Aging was associated with slowed reaction times, target stimulus processing in working memory (WM, longer N2b and P3b latencies) and selection and preparation of the motor response (longer sLRP and earlier rLRP onset latencies). In the novel relative to the standard condition we observed, in the three age groups: (1) a distraction effect, reflected in a slowing of reaction times, of stimuli categorization in WM (longer P3b latency), and of motor response selection (longer sLRP onset latency); (2) a facilitation effect on response preparation (later rLRP onset latency), and (3) an increase in arousal (larger amplitudes of all ERPs evaluated, except for N2b amplitude in the Old group). A distraction effect on the stimulus evaluation processes (longer N2b latency) were also observed, but only in middle-aged and old participants, indicating that the attentional capture slows the stimulus evaluation in WM from early ages (from 50 years onwards, without differences between middle-age and older adults), but not in young adults. PMID:25294999

The Impact of Advanced Age on Driving Safety in Adults with Medical Conditions.

PubMed

Moon, Sanghee; Ranchet, Maud; Akinwuntan, Abiodun Emmanuel; Tant, Mark; Carr, David Brian; Raji, Mukaila Ajiboye; Devos, Hannes

2018-01-01

Adults aged 85 and older, often referred to as the oldest-old, are the fastest-growing segment of the population. The rapidly increasing number of older adults with chronic and multiple medical conditions poses challenges regarding their driving safety. To investigate the effect of advanced age on driving safety in drivers with medical conditions. We categorized 3,425 drivers with preexisting medical conditions into four age groups: middle-aged (55-64 years, n = 1,386), young-old (65-74 years, n = 1,013), old-old (75-84 years, n = 803), or oldest-old (85 years and older, n = 223). All underwent a formal driving evaluation. The outcome measures included fitness to drive recommendation by the referring physician, comprehensive fitness to drive decision from an official driving evaluation center, history of motor vehicle crashes (MVCs), and history of traffic violations. The oldest-old reported more cardiopulmonary and visual conditions, but less neurological conditions than the old-old. Compared to the middle-aged, the oldest-old were more likely to be considered unfit to drive by the referring physicians (odds ratio [OR] = 4.47, 95% confidence interval [CI] 2.20-9.10) and by the official driving evaluation center (OR = 2.74, 95% CI 1.87-4.03). The oldest-old reported more MVCs (OR = 2.79, 95% CI 1.88-4.12) compared to the middle-aged. Advanced age adversely affected driving safety outcomes. The oldest-old are a unique age group with medical conditions known to interfere with safe driving. Driving safety strategies should particularly target the oldest-old since they are the fastest-growing group and their increased frailty is associated with severe or fatal injuries due to MVCs. © 2018 S. Karger AG, Basel.

Impacts of post-mortem ageing prior to freezing on technological and oxidative properties of coarse ground lamb sausage in a model system.

PubMed

Choe, Juhui; Kim, Hyun-Wook; Farouk, Mustafa M; Brad Kim, Yuan H

2017-07-01

The objective of this study was to evaluate the effects of ageing time of lamb loins prior to freezing on technological characteristics and oxidation stability of coarse ground lamb loin sausage using in a model system. Lamb loins ( M. longissimus lumborum , n = 25) were aged at -1.5°C for 0, 1, 2, 3, and 8 wk and then frozen for the remaining days (a total of 30 wk). The aged/frozen/thawed lamb loins were ground, and model sausages were formulated with 75% aged/frozen/thawed lamb loin, 25% water, 1.5% sodium chloride (NaCl) and 0.3% sodium tripolyphosphate. The pH and thaw/purge loss of aged/frozen/thawed lamb loins were evaluated, and protein functionality (protein solubility and emulsifying capacity), water-holding capacity and textural properties of model sausages were determined. Cooked model sausages were vacuum-packaged in a plastic bag and displayed under continuous fluorescent natural white light (3°C±1°C). Colour and lipid oxidation of the cooked model sausages were evaluated on 0 and 21 d of display storage. Ageing prior to freezing had no impact on pH and purge/thaw loss of lamb loins and the colour of cooked sausages (p>0.05) made from the loins. Lamb loins aged for at least 3 wk prior to freezing numerically improved total and myofibrillar protein solubilities (p>0.05) and emulsion activity index (p = 0.009) of meat batter, but decreased cooking loss (p = 0.003) and lipid oxidation (p<0.05) of model sausages. This study suggests that post-mortem ageing of raw meat prior to freezing could improve water-holding capacity and lipid oxidative stability of sausage made from the meat.

Prevalence of androgen deficiency in men with erectile dysfunction.

PubMed

Köhler, Tobias S; Kim, Johnny; Feia, Kendall; Bodie, Josh; Johnson, Nick; Makhlouf, Antoine; Monga, Manoj

2008-04-01

Erectile dysfunction (ED) and androgen deficiency in aging men are two separate clinical entities that often overlap. Controversy exists regarding the most appropriate total testosterone level that defines androgen deficiency in aging men, and its prevalence in men with ED is still uncertain. We evaluated the prevalence and risk factors of low and low-normal testosterone levels in men presenting for an initial ED evaluation. The computerized charts from 1987 to 2002 of 2794 men aged 25 to 80 years and presenting with a primary complaint of ED who also had serum total testosterone levels measured were retrospectively reviewed. Multiple testosterone level cutpoints and a linear regression model (including age, diabetes, cholesterol, anemia, creatinine, and prostate-specific antigen) were used to analyze the factors that correlated with hypogonadism. The prevalence of androgen deficiency was 7%, 23%, 33%, and 47% for testosterone levels of less than 200, less than 300, less than 346, and less than 400 ng/dL, respectively. An abrupt increase in hypogonadism prevalence occurred in men aged 45 to 50, beyond which a plateau of prevalence was maintained until older than 80 years of age. Age, the presence of uncontrolled diabetes, high total cholesterol, and anemia all correlated with significantly decreased testosterone levels in men with ED. The prostate-specific antigen level and creatinine did not affect the testosterone levels. Androgen deficiency was quite common in men presenting with ED and correlated significantly with age, uncontrolled diabetes, hypercholesteremia, and anemia. Although additional prospective studies evaluating the effect of testosterone supplementation in this population are needed, clinicians, including urologists, should be keenly aware of the large overlap of patients with ED who might also have the entity, androgen deficiency in the aging male.

L-carnitine significantly decreased aging of rat adipose tissue-derived mesenchymal stem cells.

PubMed

Mobarak, Halimeh; Fathi, Ezzatollah; Farahzadi, Raheleh; Zarghami, Nosratollah; Javanmardi, Sara

2017-03-01

Mesenchymal stem cells are undifferentiated cells that have the ability to divide continuously and tissue regeneration potential during the transplantation. Aging and loss of cell survival, is one of the main problems in cell therapy. Since the production of free radicals in the aging process is effective, the use of antioxidant compounds can help in scavenging free radicals and prevent the aging of cells. The aim of this study is evaluate the effects of L-carnitine (LC) on proliferation and aging of rat adipose tissue-derived mesenchymal stem cells (rADSC). rADSCs were isolated from inguinal region of 5 male Rattus rats. Oil red-O, alizarin red-S and toluidine blue staining were performed to evaluate the adipogenic, osteogenic and chondrogenic differentiation of rADSCs, respectively. Flow cytometric analysis was done for investigating the cell surface markers. The methyl thiazol tetrazolium (MTT) method was used to determine the cell proliferation of rADSCs following exposure to different concentrations of LC. rADSCs aging was evaluated by beta-galactosidase staining. The results showed significant proliferation of rADSCs 48 h after treatment with concentrations of 0.2 mM LC. In addition, in the presence of 0.2 mM LC, rADSCs appeared to be growing faster than control group and 0.2 mM LC supplementation could significantly decrease the population doubling time and aging of rADSCs. It seems that LC would be a good antioxidant to improve lifespan of rADSCs due to the decrease in aging.

Aging of vestibular function evaluated using correlational vestibular autorotation test

PubMed Central

Hsieh, Li-Chun; Lin, Hung-Ching; Lee, Guo-She

2014-01-01

Background Imbalance from degeneration of vestibular end organs is a common problem in the elderly. However, the decline of vestibular function with aging was revealed in few vestibular function tests such as vestibular autorotation test (VAT). In the current VAT, there are drawbacks of poor test–retest reliability, slippage of the sensor at high-speed rotations, and limited data about the effect of aging. We developed a correlational-VAT (cVAT) system that included a small, light sensor (less than 20 g) with wireless data transmission technique to evaluate the aging of vestibular function. Material and methods We enrolled 53 healthy participants aged between 25 and 75 years and divided them into five age groups. The test conditions were vertical and horizontal head autorotations of frequencies from 0 to 3 Hz with closed eyes or open eyes. The cross-correlation coefficient (CCC) between eye velocity and head velocity was obtained for the head autorotations between 1 Hz and 3 Hz. The mean of the CCCs was used to represent the vestibular function. Results Age was significantly and negatively correlated with the mean CCC for all test conditions, including horizontal or vertical autorotations with open eyes or closed eyes (P<0.05). The mean CCC with open eyes declined significantly at 55–65 years old and the mean CCC with closed eyes declined significantly at 65–75 years old. Conclusion Vestibular function evaluated using mean CCC revealed a decline with age, and the function of visual-vestibulo-ocular reflex declined 10 years earlier than the function of vestibulo-ocular reflex. PMID:25214774

Development of skin aging scale by using dermoscopy.

PubMed

Isik, Burcu; Gurel, Mehmet S; Erdemir, Asli T; Kesmezacar, Ozgu

2013-05-01

Some features of skin aging that cannot be detected by the naked eye can be determined more easily by dermoscopy. Therefore, we aimed to measure skin aging with dermoscopy. The study was performed in Istanbul Training and Research Hospital, a tertiary care referral center. A total of 441 participants between the ages of 20-88 (mean 48.4 ± 17.7) were separated into six groups according to their age. All participant's facial sun-exposed areas were examined by dermoscopy in terms of telangiectasia, vascular changes, pigmentation changes, seborrheic keratosis, actinic keratosis, periorbital comedones and cysts, superficial- deep- criss-cross wrinkles as the signs of photoaging and scored with the help of dermoscopic photoaging scale (DPAS). The validity of the scale was assessed with DPAS by the evaluation of both the axillar and the gluteal regions, that were not sun exposed and photoaged, with DPAS. The scale was found to be highly reliable as Cronbach's α coefficient was 0.756. Skin aging of patients from every decade was compared clinically with Glogou photoaging scale and Monheit-Fulton photoaging index and significant correlation was calculated as 0.773 and 0.774, respectively. An increase in photoaging scores from young people toward elders according to their ages was observed and the same linear difference between their mean values was detected. DPAS is a reliable and valid diagnostic tool that can evaluate photoaged skin quantitatively by the help of objective criteria so can be used to evaluate the effect of preventive and therapeutic applications for skin aging. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.

Precision and accuracy of age estimates obtained from anal fin spines, dorsal fin spines, and sagittal otoliths for known-age largemouth bass

USGS Publications Warehouse

Klein, Zachary B.; Bonvechio, Timothy F.; Bowen, Bryant R.; Quist, Michael C.

2017-01-01

Sagittal otoliths are the preferred aging structure for Micropterus spp. (black basses) in North America because of the accurate and precise results produced. Typically, fisheries managers are hesitant to use lethal aging techniques (e.g., otoliths) to age rare species, trophy-size fish, or when sampling in small impoundments where populations are small. Therefore, we sought to evaluate the precision and accuracy of 2 non-lethal aging structures (i.e., anal fin spines, dorsal fin spines) in comparison to that of sagittal otoliths from known-age Micropterus salmoides (Largemouth Bass; n = 87) collected from the Ocmulgee Public Fishing Area, GA. Sagittal otoliths exhibited the highest concordance with true ages of all structures evaluated (coefficient of variation = 1.2; percent agreement = 91.9). Similarly, the low coefficient of variation (0.0) and high between-reader agreement (100%) indicate that age estimates obtained from sagittal otoliths were the most precise. Relatively high agreement between readers for anal fin spines (84%) and dorsal fin spines (81%) suggested the structures were relatively precise. However, age estimates from anal fin spines and dorsal fin spines exhibited low concordance with true ages. Although use of sagittal otoliths is a lethal technique, this method will likely remain the standard for aging Largemouth Bass and other similar black bass species.

Leg Strength Comparison between Younger and Middle-age Adults

PubMed Central

Kim, Sukwon; Lockhart, Thurmon; Nam, Chang S.

2009-01-01

Although a risk of occupational musculoskeletal diseases has been identified with age-related strength degradation, strength measures from working group are somewhat sparse. This is especially true for the lower extremity strength measures in dynamic conditions (i.e., isokinetic). The objective of this study was to quantify the lower extremity muscle strength characteristics of three age groups (young, middle, and the elderly). Total of 42 subjects participated in the study: 14 subjects for each age group. A commercial dynamometer was used to evaluate isokinetic and isometric strength at ankle and knee joints. 2 × 2 (Age group (younger, middle-age, and older adult groups) × Gender (male and female)) between-subject design and Post-hoc analysis were performed to evaluate strength differences among three age groups. Post-hoc analysis indicated that, overall, middle-age workers’ leg strengths (i.e. ankle and knee muscles) were significantly different from younger adults while middle-age workers’ leg strengths were virtually identical to older adults’ leg strengths. These results suggested that, overall, 14 middle-age workers in the present study could be at a higher risk of musculoskeletal injuries. Future studies looking at the likelihood of musculoskeletal injuries at different work places and from different working postures at various age levels should be required to validate the current findings. The future study would be a valuable asset in finding intervention strategies such that middle-age workers could stay healthier longer. PMID:20436934

[Hygienic evaluation of immune and endocrine systems and modifications of their relationship in reproductive-age women working under exposure to chemical factors in activated carbon emissions].

PubMed

Lanin, D V; Zaĭtseva, N V; Dolgikh, O V; Zemlianova, M A; Kir'ianov, D A

2013-01-01

The article presents results of the evaluation the changes in the relationships between immune and endocrine systems in reproductive-age women, working under exposure to chemical factors from activated carbon production. A significant increase of some chemical elements and compounds was found in blood that was associated with changes in the endocrine and immune status, as well as the presence of features in correlation parameters of these systems in reproductive-age women, working under exposure to chemical factors.

Quantitative relations between fishing mortality, spawning stress mortality and biomass growth rate (computed with numerical model FISHMO)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laevastu, T.

1983-01-01

The effects of fishing on a given species biomass have been quantitatively evaluated. A constant recruitment is assumed in this study, but the evaluation can be computed on any known age distribution of exploitable biomass. Fishing mortality is assumed to be constant with age; however, spawning stress mortality increases with age. When fishing (mortality) increases, the spawning stress mortality decreases relative to total and exploitable biomasses. These changes are quantitatively shown for two species from the Bering Sea - walleye pollock, Theragra chalcogramma, and yellowfin sole, Limanda aspera.

Evaluation de L’Effet du Vieillissement des Equipages sur les Consequences du Decalage Horaire (Evaluation of Crew Members Aging on Jet-Lag Consequences)

DTIC Science & Technology

2000-08-01

Ergonomia , 1987, 30, 13 79- physique que psychologique. Cela tend A damontrer que 1393. dans des conditions militaires op~rationnelles, les 2...melatonin. Ergonomia , 1987, 30, 1379- 1393. 2 - BLOIS R, FEINBERG I., GAILLARD J.M., KUPFER D.J. and WEBB W.B. Sleep in normal and pathological aging

Evaluation of a Group Intervention to Assist Aging Parents with Permanency Planning for an Adult Offspring with Special Needs

ERIC Educational Resources Information Center

Botsford, Anne L.; Rule, David

2004-01-01

More than three-fourths of older adults with developmental disabilities and mental illness live in the community with aging parents, the majority of whom do not complete plans for the residential, financial, and legal future of their offspring. The authors used a true experimental design to evaluate the effectiveness of a six-week…

Predicting Vocabulary Growth in Children with and without Specific Language Impairment: A Longitudinal Study from 2;6 to 21 Years of Age

ERIC Educational Resources Information Center

Rice, Mabel L.; Hoffman, Lesa

2015-01-01

Purpose: Children with specific language impairment (SLI) often have vocabulary impairments. This study evaluates longitudinal growth in a latent trait of receptive vocabulary in affected and unaffected children ages 2;6 (years;months) to 21 years and evaluates as possible predictors maternal education, child gender, and nonverbal IQ. Method: A…

The Evaluation of Burnout Levels of Sports Sciences Faculty Students

ERIC Educational Resources Information Center

Kocaeksi, Serdar

2016-01-01

The aim of this research is to evaluate the burnout levels of sports sciences faculty students in terms of some other variables. 46 Female (Age, M: 20.88 ± 1.86) and 107 male (Age, M: 22.15 ± 2.15) in total 153 students participated in this research. Maslach Burnout Inventory-Student Form (MBI-SF) was used for data collection. Descriptive…

Development and Validation of a Short-Form Adaptation of the Age-Related Vision Loss Scale: The AVL12

ERIC Educational Resources Information Center

Horowitz, Amy; Reinhardt, Joann P.; Raykov, Tenko

2007-01-01

This article describes the development and evaluation of a short form of the 24-item Adaptation to Age-Related Vision Loss (AVL) scale. The evaluation provided evidence of the reliability and validity of the short form (the AVL12), for significant interindividual differences at the baseline and for individual-level change in AVL scores over time.…

Quality Care for School-Age Children: A Self-Instructional Guide To Help Staff Plan and Implement a Quality Program for School-Age Children.

ERIC Educational Resources Information Center

Childcare Resources, Birmingham, AL.

The purpose of this manual is to provide school-age child care center staff in Alabama with information about school-age children that facilitates program planning and provides a basis for implementing and evaluating a high quality school-age child care (SACC) program. Sections of the manual discuss: (1) teacher competencies addressed by the…

eNOS-uncoupling in age-related erectile dysfunction

PubMed Central

Johnson, JM; Bivalacqua, TJ; Lagoda, GA; Burnett, AL; Musicki, B

2011-01-01

Aging is associated with ED. Although age-related ED is attributed largely to increased oxidative stress and endothelial dysfunction in the penis, the molecular mechanisms underlying this effect are not fully defined. We evaluated whether endothelial nitric oxide synthase (eNOS) uncoupling in the aged rat penis is a contributing mechanism. Correlatively, we evaluated the effect of replacement with eNOS cofactor tetrahydrobiopterin (BH4) on erectile function in the aged rats. Male Fischer 344 ‘young’ (4-month-old) and ‘aged’ (19-month-old) rats were treated with a BH4 precursor sepiapterin (10 mg/kg intraperitoneally) or vehicle for 4 days. After 1-day washout, erectile function was assessed in response to electrical stimulation of the cavernous nerve. Endothelial dysfunction (eNOS uncoupling) and oxidative stress (thiobarbituric acid reactive substances, TBARS) were measured by conducting western blot in penes samples. Erectile response was significantly reduced in aged rats, whereas eNOS uncoupling and TBARS production were significantly increased in the aged rat penis compared with young rats. Sepiapterin significantly improved erectile response in aged rats and prevented increase in TBARS production, but did not affect eNOS uncoupling in the penis of aged rats. These findings suggest that aging induces eNOS uncoupling in the penis, resulting in increased oxidative stress and ED. PMID:21289638

Evaluating Alzheimer's disease biomarkers as mediators of age-related cognitive decline.

PubMed

Hohman, Timothy J; Tommet, Doug; Marks, Shawn; Contreras, Joey; Jones, Rich; Mungas, Dan

2017-10-01

Age-related changes in cognition are partially mediated by the presence of neuropathology and neurodegeneration. This manuscript evaluates the degree to which biomarkers of Alzheimer's disease, (AD) neuropathology and longitudinal changes in brain structure, account for age-related differences in cognition. Data from the AD Neuroimaging Initiative (n = 1012) were analyzed, including individuals with normal cognition and mild cognitive impairment. Parallel process mixed effects regression models characterized longitudinal trajectories of cognitive variables and time-varying changes in brain volumes. Baseline age was associated with both memory and executive function at baseline (p's < 0.001) and change in memory and executive function performances over time (p's < 0.05). After adjusting for clinical diagnosis, baseline, and longitudinal changes in brain volume, and baseline levels of cerebrospinal fluid biomarkers, age effects on change in episodic memory and executive function were fully attenuated, age effects on baseline memory were substantially attenuated, but an association remained between age and baseline executive function. Results support previous studies that show that age effects on cognitive decline are fully mediated by disease and neurodegeneration variables but also show domain-specific age effects on baseline cognition, specifically an age pathway to executive function that is independent of brain and disease pathways. Copyright © 2017 Elsevier Inc. All rights reserved.

The value of shear wave elastography in the quantification of corpus cavernosum penis rigidity and its alteration with age.

PubMed

Inci, Ercan; Turkay, Rustu; Nalbant, Mustafa Orhan; Yenice, Mustafa Gurkan; Tugcu, Volkan

2017-04-01

The goal of this study was to measure corpus cavernosum (CC) penis rigidity with shear wave elastography (SWE) in healthy volunteers and to evaluate the change of rigidity with age. SWE was performed in 60 healthy volunteers (age range 20-71, mean 47±12,83 years). Volunteers were divided into 2 groups by age (Group 1 age <50, group 2 age ≥50). We assessed SWE in 3 parts of penis (proximal, middle and glans penis) on both sides of CC. All values of SWE (in kilo Pascal) were noted along with volunteers' ages. The measurements were done both with transverse (T) and longitudinal (L) sections. We compared all SW values of penis parts and their alterations with age. The shear wave elastography values of CC penis increased with increasing age (p<0,01). There was no significant difference between both sides of CC penis (p<0,05). We calculated no significant difference between T and L sections of all parts of penis (p<0,05). SWE can provide noninvasive quantitative data of CC penis rigidity and its alteration with age. These data may create a new approach in the evaluation process and treatment options for penile pathologies. Copyright © 2017 Elsevier B.V. All rights reserved.

Active aging is associated with low prevalence of depressive symptoms among Brazilian older adults.

PubMed

Galli, Rosangela; Moriguchi, Emílio Hideyuki; Bruscato, Neide Maria; Horta, Rogerio Lessa; Pattussi, Marcos Pascoal

2016-01-01

Active aging is the process of optimizing opportunities for health, participation and security, aiming to improve quality of life as people age. A series of studies had demonstrated that a lower prevalence of depression is found among more active elderly. To evaluate the association between indicators of active aging and depressive symptoms among the elderly (aged 60 years or more). A population-based cross-sectional study was conducted with 1,006 elderly people (aged 60 years or over) from a small-sized Brazilian municipality. Depressive symptoms were assessed using the Geriatric Depression Scale - 15, with cutoff point ≥ 6 symptoms. Active aging was evaluated using indicators such as: active occupational situation, manual work, reading and physical activities. Data analyses used modified Poisson regression to obtain crude and adjusted prevalence ratios (PR). Most of the elderly people were: white, women and aged between 60 and 74 years. All the indicators of active aging were associated with the outcome. After controlling for socioeconomic, demographic and health variables, elderly people who worked, participated in groups, did manual work and maintained interests such as reading and talking to friends had lower prevalence of depressive symptoms compared to those not doing these activities. Active aging approaches may serve as a valuable mental health promotion strategy aimed at the elderly.

Age Validation in the Long Life Family Study Through a Linkage to Early-Life Census Records

PubMed Central

2013-01-01

Objectives. Studies of health and longevity require accurate age reporting. Age misreporting among older adults in the United States is common. Methods. Participants in the Long Life Family Study (LLFS) were matched to early-life census records. Age recorded in the census was used to evaluate age reporting in the LLFS. The study population was 99% non-Hispanic white. Results. About 88% of the participants were matched to 1910, 1920, or 1930 U.S. censuses. Match success depended on the participant’s education, place of birth, and the number of censuses available to be searched. Age at the time of the interview based on the reported date of birth and early-life census age were consistent for about 89% of the participants, and age consistency within 1 year was found for about 99% of the participants. Discussion. It is possible to match a high fraction of older study participants to their early-life census records when detailed information is available on participants’ family of origin. Such record linkage can provide an important source of information for evaluating age reporting among the oldest old participants. Our results are consistent with recent studies suggesting that age reporting among older whites in the United States appears to be quite good. PMID:23704206

Ponseti's manipulation in neglected clubfoot in children more than 7 years of age: a prospective evaluation of 25 feet with long-term follow-up.

PubMed

Khan, Shah Alam; Kumar, Ashok

2010-09-01

We wanted to evaluate the efficacy of Ponseti's technique in neglected clubfoot in children more than 7 years of age. The results of Ponseti's method were evaluated in 21 children (25 feet) with neglected club feet. Patients were evaluated using the Dimeglio scoring system. All patients underwent percutaneous tenotomy of the Achilles tendon. The mean age at the time of treatment was 8.9 years. The mean follow-up period was 4.7 years. The average Dimeglio score at the start of the treatment was 14.2 compared with an average score of 0.95 at the end of the treatment at 1-year follow-up. Eighteen feet (85.7%) had full correction. Recurrence was seen in six feet (24%). At 4-year follow-up, the average Dimeglio score for 19 feet was 0.18. We recommend that Ponseti's method should be the preferred initial treatment modality for neglected clubfeet.

Evaluation of concentric left ventricular geometry in humans: evidence for age-related systematic underestimation.

PubMed

de Simone, Giovanni; Daniels, Stephen R; Kimball, Thomas R; Roman, Mary J; Romano, Carmela; Chinali, Marcello; Galderisi, Maurizio; Devereux, Richard B

2005-01-01

There might be limitations in identifying concentric left ventricular (LV) geometry by ratio of diastolic posterior wall thickness (WT(p)) to cavity radius, defined as relative wall thickness (RWT(p)). This study has been designed to evaluate age effects on RWT(p). WT(p), mean of septal thickness and WT(p) (WT(m)), and cavity radius were cross-sectionally evaluated in 766 1- to 85-year-old, normotensive, nonobese subjects and 331 hypertensive Italians (used as a test series). RWT(p) > or =0.43 defined "traditional" concentric LV geometry. The ratios WT(m)/radius (RWT(m)) and RWT(p) increased by 0.005 and 0.006 per year of age in the age stratum up to 17 years and by 0.002 in the older age stratum (18 years or older; all P<0.0001). Thus, RWT(m) and RWT(p) were normalized to average age in both age strata (10 and 46 years) by age-specific regression coefficients. The 90th and 95th percentiles of age-normalized RWT(p) or RWT(m) were 0.40 and 0.42 or 0.41 and 0.43, respectively, in adults and 0.36 and 0.39 or 0.36 and 0.38, respectively in young subjects. In hypertensive subjects, traditional RWT(p) cutoff identified 74 subjects (22%) with concentric LV geometry; by 95th or 90th normal percentiles, normalized RWT(m) identified 112 (34%), or 149 (45%) subjects with concentric LV geometry, and normalized RWT(p) 29% and 39%, respectively (all P<0.0001 versus unadjusted RWT(p)). Thus, prevalence of concentric LV geometry increases with age-normalized RWT. Accordingly, we suggest that concentric LV hypertrophy be defined by coexistence of high LV mass with age-normalized RWT(m) >0.41 or RWT(p) >0.40. Further studies are required to establish prognostic implications of our findings.

Evaluation of an aged care nurse practitioner service: quality of care within a residential aged care facility hospital avoidance service.

PubMed

Dwyer, Trudy; Craswell, Alison; Rossi, Dolene; Holzberger, Darren

2017-01-13

Reducing avoidable hospitialisation of aged care facility (ACF) residents can improve the resident experience and their health outcomes. Consequently many variations of hospital avoidance (HA) programs continue to evolve. Nurse practitioners (NP) with expertise in aged care have the potential to make a unique contribution to hospital avoidance programs. However, little attention has been dedicated to service evaluation of this model and the quality of care provided. The purpose of this study was to evaluate the quality of an aged care NP model of care situated within a HA service in a regional area of Australia. Donabedian's structure, process and outcome framework was applied to evaluate the quality of the NP model of care. The Australian Nurse Practitioner Study standardised interview schedules for evaluating NP models of care guided the semi-structured interviews of nine health professionals (including ACF nurses, medical doctors and allied health professionals), four ACF residents and their families and two NPs. Theory driven coding consistent with the Donabedian framework guided analysis of interview data and presentation of findings. Structural dimensions identified included the 'in-reach' nature of the HA service, distance, limitations of professional regulation and the residential care model. These dimensions influenced the process of referring the resident to the NP, the NPs timely response and interactions with other professionals. The processes where the NPs take time connecting with residents, initiating collaborative care plans, up-skilling aged care staff and function as intra and interprofessional boundary spanners all contributed to quality outcomes. Quality outcomes in this study were about timely intervention, HA, timely return home, partnering with residents and family (knowing what they want) and resident and health professional satisfaction. This study provides valuable insights into the contribution of the NP model of care within an aged care, HA service and how staff manipulated the process dimensions to improve referral to the NPs. NP service in this study was dynamic, flexible and responsive to both patient and organisational demands.

Childhood hair product use and earlier age at menarche in a racially diverse study population: a pilot study.

PubMed

James-Todd, Tamarra; Terry, Mary Beth; Rich-Edwards, Janet; Deierlein, Andrea; Senie, Ruby

2011-06-01

Previous studies suggest that hair products containing endocrine disrupting chemicals could alter puberty. We evaluated the association between childhood hair product use and age at menarche in a racially diverse study population. We recruited 300 African-American, African-Caribbean, Hispanic, and white women from the New York City metropolitan area who were between 18-77 years of age. Data were collected retrospectively on hair oil, lotion, leave-in conditioner, perm, and other types of hair products used before age 13. Recalled age at menarche ranged from 8 to 19 years. We used multivariable binomial regression to evaluate the association between hair product use and age at menarche (<12 vs. ≥12), adjusting for potential confounders. African-Americans were more likely to use hair products and reached menarche earlier than other racial/ethnic groups. Women reporting childhood hair oil use had a risk ratio of 1.4 (95% confidence interval [CI]: 1.1-1.9) for earlier menarche, adjusting for race/ethnicity and year of birth. Hair perm users had an increased risk for earlier menarche (adjusted risk ratio = 1.4, 95% CI: 1.1-1.8). Other types of hair products assessed in this study were not associated with earlier menarche. Childhood hair oil and perm use were associated with earlier menarche. If replicated, these results suggest that hair product use may be important to measure in evaluating earlier age at menarche. Copyright © 2011 Elsevier Inc. All rights reserved.

Analyses of changes on skin by aging.

PubMed

Kazanci, A; Kurus, M; Atasever, A

2017-02-01

This study aimed to evaluate the histological changes occurring in rat skin with increasing age, starting from the intrauterine period. Thirty-two healthy female Sprague-Dawley rats were evaluated in four groups: group 1 - intrauterine day 19, group 2 - postpartum day 21, group 3 - postpartum day 60, and group 4 - postpartum month 19. Skin samples from the back, abdomen, head, and upper and lower limbs were obtained from each subject under anesthesia. Tissue specimens were evaluated statistically and morphologically for the thicknesses of the epidermis, dermis, and basement membrane; the number, height, and width of dermal papillae; and the mast cell and pilosebaceous counts per group. The changes in collagen/elastic fibers and glycosaminoglycans were also assessed. Epidermal thickness was the highest in the intrauterine group; it decreased in the postpartum period and increased again in the aged group. Basal membrane thickness increased steadily with age. The number, height, and width of dermal papillae and dermal thickness increased up to day 60 after birth although these decreased in the aged group. Mast cell count also reached the maximum in the intrauterine group and gradually decreased with age. Pilosebaceous units of the dermis were fewer in intrauterine specimens; they showed an increase during the postpartum period and a decrease in the aged group. Skin specimens obtained from rats showed striking differences between the intrauterine and postpartum groups. Moreover, the postpartum group showed considerable intra-group differences. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Auditory pathway maturational study in small for gestational age preterm infants.

PubMed

Angrisani, Rosanna Giaffredo; Diniz, Edna Maria Albuquerque; Guinsburg, Ruth; Ferraro, Alexandre Archanjo; Azevedo, Marisa Frasson de; Matas, Carla Gentile

2014-01-01

To follow up the maturation of the auditory pathway in preterm infants small for gestational age (SGA), through the study of absolute and interpeak latencies of auditory brainstem response (ABR) in the first six months of age. This multicentric prospective cross-sectional and longitudinal study assessed 76 newborn infants, 35 SGA and 41 appropriate for gestational age (AGA), born between 33 and 36 weeks in the first evaluation. The ABR was carried out in three moments (neonatal period, three months and six months). Twenty-nine SGA and 33 AGA (62 infants), between 51 and 54 weeks (corrected age), returned for the second evaluation. In the third evaluation, 49 infants (23 SGA and 26 AGA), with age range from 63 to 65 weeks (corrected age), were assessed. The bilateral presence of Transient Evoked Otoacoustic Emissions and normal tympanogram were inclusion criteria. It was found interaural symmetry in both groups. The comparison between the two groups throughout the three periods studied showed no significant differences in the ABR parameters, except for the latencies of wave III in the period between three and six months. As for the maturation with tone burst 0.5 and 1 kHz, it was found that the groups did not differ. The findings suggest that, in the premature infants, the maturational process of the auditory pathway occurs in a similar rate for SGA and AGA. These results also suggest that prematurity is a more relevant factor for the maturation of the auditory pathway than birth weight.

The effect of aging on efferent nerve fibers regeneration in mice.

PubMed

Verdú, E; Butí, M; Navarro, X

1995-10-23

This study evaluates the influence of aging on nerve regeneration and reinnervation of target organs in mice aged 2, 6, 9, 12, 18 and 24 months. In animals of each age group the sciatic nerve was subjected to crush, section or section and suture. Reinnervation of plantar muscles and sweat glands (SG) was evaluated over three months after operation by functional methods. Reappearance of SG secretion and motor responses occurred slightly earlier in young than older mice. The degree of motor and sudomotor reinnervation, with respect to preoperative control values, was also significantly higher in young than old animals. The differences were more pronounced after 12 months of age. The degree of recovery progressively decreased with the severity of the lesion, differences being more marked in older mice. Neurorraphy improved recovery, comparatively more in older than in young mice. These results indicate that, after injuries of peripheral nerves, axonal regeneration and reinnervation are maintained throughout life, but tend to be more delayed and slightly less effective with aging.

Major salivary gland flow rates in young and old, generally healthy African Americans and whites.

PubMed Central

Jones, R. E.; Ship, J. A.

1995-01-01

Saliva is essential to maintain and preserve oral health. Previous studies of primarily white populations demonstrated that salivary gland flow rates are age-stable in healthy adults, but there are little data on African Americans of different ages. The purpose of this study was to determine if there is a relationship between age, gender, and race in unstimulated and stimulated parotid and submandibular salivary gland flow rates and to evaluate subjective responses to questions regarding salivary dysfunction. Sixty generally healthy, middle socioeconomic class African Americans and whites between the ages of 20 to 40 and 60 to 80 years were evaluated. The results indicate, in general, that objective and subjective measurements of major salivary gland flow rates are independent of age, gender, and race. Further studies are required using larger populations. These results suggest that signs and symptoms of dry mouth in the elderly regardless of race or gender should not be considered a normal sequela of aging. PMID:7897685

Age estimation by assessment of pulp chamber volume: a Bayesian network for the evaluation of dental evidence.

PubMed

Sironi, Emanuele; Taroni, Franco; Baldinotti, Claudio; Nardi, Cosimo; Norelli, Gian-Aristide; Gallidabino, Matteo; Pinchi, Vilma

2017-11-14

The present study aimed to investigate the performance of a Bayesian method in the evaluation of dental age-related evidence collected by means of a geometrical approximation procedure of the pulp chamber volume. Measurement of this volume was based on three-dimensional cone beam computed tomography images. The Bayesian method was applied by means of a probabilistic graphical model, namely a Bayesian network. Performance of that method was investigated in terms of accuracy and bias of the decisional outcomes. Influence of an informed elicitation of the prior belief of chronological age was also studied by means of a sensitivity analysis. Outcomes in terms of accuracy were adequate with standard requirements for forensic adult age estimation. Findings also indicated that the Bayesian method does not show a particular tendency towards under- or overestimation of the age variable. Outcomes of the sensitivity analysis showed that results on estimation are improved with a ration elicitation of the prior probabilities of age.

Evaluation of selected auditory tests in school-age children suspected of auditory processing disorders.

PubMed

Vanniasegaram, Iyngaram; Cohen, Mazal; Rosen, Stuart

2004-12-01

To compare the auditory function of normal-hearing children attending mainstream schools who were referred for an auditory evaluation because of listening/hearing problems (suspected auditory processing disorders [susAPD]) with that of normal-hearing control children. Sixty-five children with a normal standard audiometric evaluation, ages 6-14 yr (32 of whom were referred for susAPD, with the rest age-matched control children), completed a battery of four auditory tests: a dichotic test of competing sentences; a simple discrimination of short tone pairs differing in fundamental frequency at varying interstimulus intervals (TDT); a discrimination task using consonant cluster minimal pairs of real words (CCMP), and an adaptive threshold task for detecting a brief tone presented either simultaneously with a masker (simultaneous masking) or immediately preceding it (backward masking). Regression analyses, including age as a covariate, were performed to determine the extent to which the performance of the two groups differed on each task. Age-corrected z-scores were calculated to evaluate the effectiveness of the complete battery in discriminating the groups. The performance of the susAPD group was significantly poorer than the control group on all but the masking tasks, which failed to differentiate the two groups. The CCMP discriminated the groups most effectively, as it yielded the lowest number of control children with abnormal scores, and performance in both groups was independent of age. By contrast, the proportion of control children who performed poorly on the competing sentences test was unacceptably high. Together, the CCMP (verbal) and TDT (nonverbal) tasks detected impaired listening skills in 56% of the children who were referred to the clinic, compared with 6% of the control children. Performance on the two tasks was not correlated. Two of the four tests evaluated, the CCMP and TDT, proved effective in differentiating the two groups of children of this study. The application of both tests increased the proportion of susAPD children who performed poorly compared with the application of each test alone, while reducing the proportion of control subjects who performed poorly. The findings highlight the importance of carrying out a complete auditory evaluation in children referred for medical attention, even if their standard audiometric evaluation is unremarkable.

Daily emotional states as reported by children and adolescents.

PubMed

Larson, R; Lampman-Petraitis, C

1989-10-01

Hour-to-hour emotional states reported by children, ages 9-15, were examined in order to evaluate the hypothesis that the onset of adolescence is associated with increased emotional variability. These youths carried electronic pagers for 1 week and filled out reports on their emotional states in response to signals received at random times. To evaluate possible age-related response sets, a subset of children was asked to use the same scales to rate the emotions shown in drawings of 6 faces. The expected relation between daily emotional variability and age was not found among the boys and was small among the girls. There was, however, a linear relation between age and average mood states, with the older participants reporting more dysphoric average states, especially more mildly negative states. An absence of age difference in the ratings of the faces indicated that this relation could not be attributed to age differences in response set. Thus, these findings provide little support for the hypothesis that the onset of adolescence is associated with increased emotionality but indicate significant alterations in everyday experience associated with this age period.

Cervical cancer screening in young and elderly women of the Xingu Indigenous Park: evaluation of the recommended screening age group in Brazil.

PubMed

Speck, Neila Maria de Góis; Pinheiro, Juliana da Silva; Pereira, Erica Ribeiro; Rodrigues, Douglas; Focchi, Gustavo Rubino de Azevedo; Ribalta, Julisa Chamorro Lascasas

2015-01-01

To analyze the occurrence of atypia in the cytology/histology examinations of young women under the age of 25 years and of elderly women aged over 64 years, in the Xingu Indigenous Park and to evaluate, in a subjective manner, if the age range for screening established by the Ministry of Health and the Instituto Nacional de Câncer is appropriate for this population. The Xingu/UNIFESP Project, in partnership with the Center for Gynecological Disease Prevention, develops programs to prevent cervical cancer. The exploratory, retrospective and descriptive study of cytological and histopathological examinations of young (12-24 years) and elderly (aged 64 and over) women of the Xingu Indigenous Park, between 2005 and 2011. There was low occurrence of cytological atypia in the elderly female population, but there were occasional high-grade lesions in the indigenous youth. Interrupting screening at the limit age of 64 years, as established by the Ministry of Health and the Instituto Nacional de Câncer is justified. However, screening of young women should begin at an earlier age.

A practical formula for determining growth.

PubMed

Türkoz, Çağrı; Kaygısız, Emine; Ulusoy, Çağrı; Ateş, Can

2017-01-01

We aimed to establish a practical method to evaluate skeletal age using cervical vertebrae. The study consisted of hand-wrist and cephalometric radiographs of 324 subjects (167 girls, 157 boys; age range, 7.3-17.2 years). Skeletal ages of the subjects were calculated from hand-wrist radiographs, and cervical vertebral bodies were measured using cephalometric radiographs. A single formula based on C3 and C4 vertebral body heights with different coefficients for each gender was derived using ridge regression analysis. The correlation coefficients for vertebral and hand-wrist bone age were 0.825 and 0.856 for girls and boys, respectively. The correlations among vertebral bone age and C3 and C4 vertebral body heights were also found to be significant. The intraclass correlation (ICC) score was found to be 0.914, which shows high consistency between the two measurements of the same investigator for each C3 and C4 vertebral body height result. The formula derived for evaluating skeletal age in cephalometric radiographs is reliable and can be applied to both girl and boy subjects for legal requirements or therapeutic needs of age estimation.

Evaluation of physical activity measures used in middle-aged women.

PubMed

Pettee Gabriel, Kelley; McClain, James J; Lee, Chong D; Swan, Pamela D; Alvar, Brent A; Mitros, Melanie R; Ainsworth, Barbara E

2009-07-01

To evaluate the reliability and validity of five commonly used physical activity questionnaires (PAQ) in women aged 45-65 yr with varying physical activity (PA) levels. Data were obtained from the Evaluation of Physical Activity Measures in Middle-aged Women (PAW) Study and included 66 women (aged 52.6 +/- 5.4 yr). PAQ evaluated include Modifiable Activity Questionnaire (past week and past month version), Nurses' Health Study PAQ, Active Australia Survey, and Women's Health Initiative PAQ. Intraclass correlation coefficients (ICC) between administrations of the PAQ were used to assess test-retest reliability. Spearman rank-order correlation coefficients were used to examine the associations of PA and physical fitness data with PAQ summary estimates. Accelerometer-determined median (25th, 75th percentiles) times (min.d) spent in moderate-lifestyle [760-1951 counts (ct)], moderate-walk (1952-5724 ct), vigorous (> or =5725 ct), and combined moderate and vigorous PA (MVPA > or = 1952 ct) during the 35 d of observation were 66.0 (51.2, 81.3), 23.1 (14.1, 34.6), 0.4 (0.0, 2.3), and 24.3 (15.9, 41.6) min, respectively. The PAQ were shown to be reproducible and relatively stable over time (ICC = 0.32 to 0.91) and were associated with total counts per day (ct.d, 0.46 to 0.60, all P < 0.001), and most were associated with many facets of physical fitness, including cardiorespiratory fitness (0.36 to 0.46, P < 0.01), body composition (-0.27 to -0.34, P < 0.05), and muscular fatigue (-0.25 to -0.44, P < 0.05). The PAQ evaluated in this study were shown to be reliable and associated with PA and physical fitness measures. Current findings support the utility of these PAQ for PA assessment in research studies of middle-aged women.

Agreement between the Turkey Guidelines and the Fracture Risk Assessment Tool®-based Intervention Threshold

PubMed Central

Aydogan, Nevres Hurriyet; Tosun, Kursad

2018-01-01

Background The aim of this study was to evaluate the agreement between the fracture-risk assessment tool (FRAX®)-based intervention strategy in Turkey and the recommendations published in the Healthcare Practices Statement (HPS). Methods This descriptive cross-sectional study included individuals aged 40 to 90 years who were previously diagnosed as having osteoporosis but had not received any treatment. The intervention thresholds recommended by the National Osteoporosis Foundation for treatment were used. The criteria necessary for the start of administration of pharmacological agents in osteoporosis treatment were evaluated on the basis of the HPS guidelines. Results Of the 1,255 patients evaluated, 161 (12.8%) were male and 1,094 (87.2%) were female. In the evaluation, according to HPS, treatment was recommended for 783 patients (62.4%; HPS+) and not recommended for 472 (37.6%; HPS−). Of the 783 HPS+ patients, 391 (49.9%) were FRAX+, and of the 472 HPS− patients, 449 (95.1%) were FRAX−. A statistically significant difference was observed between the treatment recommendations of HPS and FRAX® (P<0.001). In the age group of 75 to 90 years, excellent agreement was found between the two strategies (Gwet's agreement coefficient 1=0.94). As age increased, the agreement between the two treatment strategies also increased. Conclusions The FRAX® model has different treatment recommendation rates from the HPS. The agreement between the two is at a minimal level. However, as age increased, so did the agreement between the FRAX® and the HPS treatment recommendations. In the recommendation to start pharmacological treatment primarily based on age, non-medical interventions that preserve bone density should be evaluated. PMID:29900157

Accuracy of MRI skeletal age estimation for subjects 12-19. Potential use for subjects of unknown age.

PubMed

Serinelli, Serenella; Panebianco, Valeria; Martino, Milvia; Battisti, Sofia; Rodacki, Karina; Marinelli, Enrico; Zaccagna, Fulvio; Semelka, Richard C; Tomei, Ernesto

2015-05-01

In forensic practice, there is a growing need for accurate methods of age estimation, especially in the cases of young individuals of unknown age. Age can be estimated through somatic features that are universally considered associated with chronological age. Unfortunately, these features do not always coincide with the real chronological age: for these reasons that age determination is often very difficult. Our aim is to evaluate accuracy of skeletal age estimation using Tomei's MRI method in subjects between 12 and 19 years old for forensic purposes. Two investigators analyzed MRI images of the left hand and wrist of 77 male and 74 female caucasian subjects, without chronic diseases or developmental disorders, whose age ranged from 12 to 19 years. Skeletal maturation was determined by two operators, who analyzed all MRI images separately, in blinded fashion to the chronological age. Inter-rater agreement was measured with Pearson (R (2)) coefficient. One of the examiners repeated the evaluation after 6 months, and intraobserver variation was analyzed. Bland-Altman plots were used to determine mean differences between skeletal and chronological age. Inter-rater agreement Pearson coefficient showed a good linear correlation, respectively, 0.98 and 0.97 in males and females. Bland-Altman analysis demonstrated that the differences between chronological and skeletal age are not significant. Spearman's correlation coefficient showed good correlation between skeletal and chronological age both in females (R (2) = 0.96) and in males (R (2) = 0.94). Our results show that MRI skeletal age is a reproducible method and has good correlation with chronological age.

Speech disorders did not correlate with age at onset of Parkinson's disease.

PubMed

Dias, Alice Estevo; Barbosa, Maira Tonidandel; Limongi, João Carlos Papaterra; Barbosa, Egberto Reis

2016-02-01

Speech disorders are common manifestations of Parkinson´s disease. Objective To compare speech articulation in patients according to age at onset of the disease. Methods Fifty patients was divided into two groups: Group I consisted of 30 patients with age at onset between 40 and 55 years; Group II consisted of 20 patients with age at onset after 65 years. All patients were evaluated based on the Unified Parkinson's Disease Rating Scale scores, Hoehn and Yahr scale and speech evaluation by perceptual and acoustical analysis. Results There was no statistically significant difference between the two groups regarding neurological involvement and speech characteristics. Correlation analysis indicated differences in speech articulation in relation to staging and axial scores of rigidity and bradykinesia for middle and late-onset. Conclusions Impairment of speech articulation did not correlate with age at onset of disease, but was positively related with disease duration and higher scores in both groups.

Schizotypy in adolescence: the role of gender and age.

PubMed

Fonseca-Pedrero, Eduardo; Lemos-Giráldez, Serafín; Muñiz, José; García-Cueto, Eduardo; Campillo-Alvarez, Angela

2008-02-01

Schizotypy is a multidimensional personality construct that appears to indicate psychosis proneness. Supposedly, schizotypal traits behave differently depending on a person's age and gender, but few studies have examined this relationship. In our study we used the Thinking and Perceptual Style Questionnaire and the Junior Schizotypy Scales. The sample was made up of 321 students (169 males) with an age range of 12 to 17 years. The results show significant differences in gender and age groups. Males score higher than females on Physical Anhedonia, Social Anhedonia, and Impulsive Non-Conformity scales, while females score higher or Positive Symptoms, Negative Evaluation, and Social Paranoia scales. Significant differences were also found among age groups: Unusual experiences, self-referent ideation, social paranoia, thought disorder, and negative evaluation were more frequent in later stages of adolescence. However, the meaning of this difference could be interpreted in terms of emotional turbulence rather than as a direct indicator of vulnerability to psychosis.

Changes in taste compounds, breaking properties, and sensory attributes during dry aging of beef from Japanese black cattle.

PubMed

Iida, Fumiko; Miyazaki, Yuki; Tsuyuki, Risako; Kato, Kenichi; Egusa, Ai; Ogoshi, Hiro; Nishimura, Toshihide

2016-02-01

Analysis of the quality of highly marbled beef during dry aging for 60days after slaughter showed that the changes in some qualities differed from those of conventional meat. The tenderness of these meats did not change during aging for 50days but then gradually increased until day 60. The juiciness of these meats, as determined by sensory evaluation, did not change during aging for 60days, except for a decrease on day 20. The umami intensity of these meats in the sensory evaluation and the value calculated by Glu and IMP quantification were highest on day 40. This high umami intensity was induced by the synergistic effect of umami compounds such as Glu and IMP. These results for tenderness, juiciness, umami intensity, and flavor intensity suggested that the best duration of dry aging for highly marbled beef was 40days. Copyright © 2015 Elsevier Ltd. All rights reserved.

Space/age forestry: Implications of planting density and rotation age in SRIC management decisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Merriam, R.A.; Phillips, V.D.; Liu, W.

1993-12-31

Short-rotation intensive-culture (SRIC) of promising tree crops is being evaluated worldwide for the production of methanol, ethanol, and electricity from renewable biomass resources. Planting density and rotation age are fundamental management decisions associated with SRIC energy plantations. Most studies of these variables have been conducted without the benefit of a unifying theory of the effects of growing space and rotation age on individual tree growth and stand level productivity. A modeling procedure based on field trials of Eucalyptus spp. is presented that evaluates the growth potential of a tree in the absence and presence of competition of neighboring trees inmore » a stand. The results of this analysis are useful in clarifying economic implications of different growing space and rotation age decisions that tree plantation managers must make. The procedure is readily applicable to other species under consideration for SRIC plantations at any location.« less

A preliminary mechanical property and stress corrosion evaluation of VIM-VAR work strengthened and direct aged Inconel 718 bar material

NASA Technical Reports Server (NTRS)

Montano, J. W.

1987-01-01

This report presents a preliminary mechanical property and stress corrosion evaluation of double melted (vacuum induction melted (VIM), and vacuum arc remelted (VAR)), solution treated, work strengthened and direct aged Inconel 718 alloy bar (5.50 in. (13.97 cm) diameter). Two sets of tensile specimens, one direct single aged and the other direct double aged, were tested at ambient temperature in both the longitudinal and transverse directions. Longitudinal tensile and yield strengths in excess of 200 ksi (1378.96 MPa) and 168 ksi (1158.33 MPa), respectively, were realized at ambient temperature, for the direct double aged specimen. No failures occurred in the single or double edged longitudinal and transverse tensile specimens stressed to 75 and 100 percent of their respective yield strengths and exposed to a salt fog environment for 180 days. Tensile tests performed after the stress corrosion test showed no mechanical property degradation.

An evaluation of agreement between pectoral spines and otoliths for estimating ages of catfishes

USGS Publications Warehouse

Olive, J.A.; Schramm, Harold; Gerard, Patrick D.; Irwin, E.

2011-01-01

Otoliths have been shown to provide more accurate ages than pectoral spine sections for several catfish populations; but sampling otoliths requires euthanizing the specimen, whereas spines can be sampled non-lethally. To evaluate whether, and under what conditions, spines provide the same or similar age estimates as otoliths, we examined data sets of individual fish aged from pectoral spines and otoliths for six blue catfish Ictalurus furcatus populations (n=420), 14 channel catfish Ictalurus punctatus populations (n=997), and 10 flathead catfish Pylodictus olivaris populations (n=947) from lotic and lentic waters throughout the central and eastern U.S. Logistic regression determined that agreement between ages estimated from otoliths and spines was consistently related to age, but inconsistently related to growth rate. When modeled at mean growth rate, we found at least 80% probability of no difference in spine- and otolith-assigned ages up to ages 4 and 5 for blue and channel catfish, respectively. For flathead catfish, an 80% probability of agreement between spine- and otolith-assigned ages did not occur at any age due to high incidence of differences in assigned ages even for age-1 fish. Logistic regression models predicted at least 80% probability that spine and otolith ages differed by ≤1 year up to ages 13, 16, and 9 for blue, channel, and flathead catfish, respectively. Age-bias assessment found mean spine-assigned age differed by less than 1 year from otolith-assigned age up to ages 19, 9, and 17 for blue catfish, channel catfish, and flathead catfish, respectively. These results can be used to help guide decisions about which structure is most appropriate for estimating catfish ages for particular populations and management objectives.

Economic evaluations of influenza vaccination in healthy working-age adults. Employer and society perspective.

PubMed

Wood, S C; Nguyen, V H; Schmidt, C

2000-08-01

To determine what benefits to the employer and to society are associated with influenza (flu) vaccination in healthy adults. We performed a literature review concerning cost-benefit and cost-effectiveness evaluations of influenza vaccination in healthy, working-age adults. Up to the end of 1999, we found 6 published economic evaluations on the use of influenza vaccine in healthy, working-age adults: 3 prospective studies, 1 retrospective evaluation and 2 model-based simulations. Evaluations were performed from the perspective of an employer or society. Costs were reported in the local currency used in the published evaluation, with conversions into US dollars (when not provided in the article), for comparative purposes only, according to the exchange rates of June 8 1998. Estimations of the cost-benefit of vaccination, compared with a no vaccination strategy, varied widely from a net loss of $US106.59 per infection averted in one study to savings of varying sizes in the 5 others (savings ranged from $US2.58 per dollar invested to $US46.85 per vaccinee). Studies differed in the definition of illness and the measurement of costs associated with vaccination or illness. Decision makers have not yet extended existing vaccine recommendations to cover healthy, working-age adults, partly because of the disparity among economic studies in their methods of estimating costs and measuring effects. However, the published studies seem to suggest that influenza vaccination in the healthy, working adult would be a cost-effective health intervention, at least from the perspective of an employer.

The Prevalence of Bruising Among Infants in Pediatric Emergency Departments

PubMed Central

Pierce, Mary Clyde; Magana, Julia N.; Kaczor, Kim; Lorenz, Douglas J.; Meyers, Gabriel; Bennett, Berkeley L.; Kanegaye, John T.

2015-01-01

Objective Bruising can indicate abuse for infants. Bruise prevalence among infants in the Pediatric Emergency Department (PED) setting is unknown. Our objective was to determine prevalence of bruising, associated chief complaints (CC), and frequency of abuse evaluations in previously healthy infants presenting to PEDs. Methods We conducted a prospective, observational, multi-center study of infants ≤12 months old presenting to PEDs. Structured sampling was utilized. Pediatric Emergency Medicine (PEM) clinicians performed complete skin examinations to screen for bruising. Study investigators documented skin findings, date of visit, patient's age, CC, and abuse evaluation. The primary outcome was prevalence of bruising. Secondary outcomes were prevalence of bruising based on CC and frequency of abuse evaluation. Point estimates of bruise prevalence and differences in bruise prevalence between patient subgroups were calculated with 95% confidence intervals (CI). Results Bruising was identified in 88 of 2488 infants (3.5%, 95% CI: [2.9%, 4.4%]). Rates of bruising for infants ≤5 and >5 months old were 1.3% and 6.4%, respectively (difference 5.1%, 95% CI: [3.6%, 6.8%]). For infants ≤5 months old, 83% of bruising was associated with a trauma CC and only 0.2% of infants presenting with a medical CC had bruising. PEM clinicians obtained abuse evaluations on 23% of infants with bruising and that rate increased to 50% for infants ≤ 5 months of age. Conclusions Bruising prevalence in children ≤ 12 months of age evaluated in PEDs was low, increased within age strata, and was most often associated with a trauma CC. Most bruised infants did not undergo an abuse evaluation. PMID:26233923

Design of a workstation and its evaluation under the influence of noise and illumination for an assembly task.

PubMed

Muzammil, Mohammad; Ahmad, Saman; Khan, Abid Ali; Hasan, Faisal

2011-01-01

An experimental research was conducted to design a workstation for a lock manufacturing assembly. Two experiments were conducted in the present study. Nine male subjects in the age range of 18-35 years participated in the first experiment. For the second experiment, nine subjects in each of the three age groups (viz. 17-22, 23-28 and 29-35 years) volunteered for experimental investigations. The designed workstation was evaluated under varying levels of noise and illumination for workers of different age groups. Three different workstations were evaluated. The task was performed by a worker in two different sitting positions and three settings of arms position. It was found that workstation type, backrest support and arms positions were all having a statistically significant effect on task performance. Workstation with work surface to seat height ratio of 1.82 was found to be better when the task was performed using backrest and arms were supported on the work surface. This workstation was evaluated for three different age groups of workers under different levels of noise and illumination. The results of the study showed that age of the worker, illumination level and level of noise were all contributing significantly towards task performance. The design of a workstation for assembly task would help greatly in creating a better working environment and enhancing the productivity of workers exposed to environmental stressors like noise and illumination. © 2011 - IOS Press and the authors. All rights reserved

Thyroid function abnormalities and cognitive impairment in elderly people: results of the Invecchiare in Chianti study.

PubMed

Ceresini, Graziano; Lauretani, Fulvio; Maggio, Marcello; Ceda, Gian Paolo; Morganti, Simonetta; Usberti, Elisa; Chezzi, Carlo; Valcavi, Rita; Bandinelli, Stefania; Guralnik, Jack M; Cappola, Anne R; Valenti, Giorgio; Ferrucci, Luigi

2009-01-01

To investigate thyroid function testing abnormalities in older persons and to explore the relationship between thyroid dysfunction and cognition. Cross-sectional. Community-based. One thousand one hundred seventy-one men and women aged 23 to 102. Thyroid function was evaluated by measuring plasma concentrations of thyrotropin (TSH), free thyroxine (FT4), and free triiodothyronine (FT3). Cognition was evaluated using the Mini-Mental State Examination (MMSE). Prevalence of overt and subclinical thyroid dysfunction was evaluated in different age groups (<65 vs > or =65). Age trends in TSH, FT4, and FT3 were examined in euthyroid participants. The cross-sectional association between thyroid dysfunction and MMSE score was evaluated adjusting for confounders. Subclinical hypothyroidism and subclinical hyperthyroidism were more prevalent in older than in younger participants (subclinical hypothyroidism, 3.5% vs 0.4%, P<.03; subclinical hyperthyroidism, 7.8% vs 1.9%, P<.002). In euthyroid participants, TSH and FT3 declined with age, whereas FT4 increased. Older participants with subclinical hyperthyroidism had lower MMSE scores than euthyroid subjects (22.61+/-6.88 vs 24.72+/-4.52, P<.03). In adjusted analyses, participants with subclinical hyperthyroidism were significantly more likely to have cognitive dysfunction (hazard rate=2.26, P=.003). Subtle age-related changes in FT3, FT4, and TSH occur in individuals who remain euthyroid. Subclinical hyperthyroidism is the most prevalent thyroid dysfunction in Italian older persons and is associated with cognitive impairment.

Anthropometric evaluation of pediatric patients with nonprogressive chronic encephalopathy according to different methods of classification☆

PubMed Central

Teixeira, Jéssica Socas; Gomes, Mirian Martins

2014-01-01

Objective: To perform anthropometric assessment of patients with quadriplegic, chronic non-progressive encephalopathy, comparing two distinct references of nutritional classification and to compare the estimated height to the length measured by stadiometer. Method: Cross-sectional study including 0-3-year children with quadriplegic chronic non-progressive encephalopathy in secondary public hospital. Length, weight, arm circumference, triceps skinfold and knee height were measured. The arm muscle circumference and estimated height were calculated. The following relations were evaluated: weight-for-age, length-for-age and weight-for-length, using as reference the charts of the World Health Organization (WHO) and those proposed by Krick et al. Results: Fourteen children with a mean age of 21 months were evaluated. Assessment of anthropometric indicators showed significant difference between the two classification methods to assess nutritional indicators length/age (p=0.014), weight/age (p=0.014) and weight/length (p=0.001). There was significant correlation between measured length and estimated height (r=0.796, p=0.001). Evaluation of arm circumference and triceps skinfold showed that most patients presented some degree of malnutrition. According to arm muscle circumference, most were eutrophic. Conclusions: Specific curves for children with chronic non-progressive encephalopathy appear to underestimate malnutrition when one takes into account indicators involving weight. Curves developed for healthy children can be a good option for clinical practice and weight-for-length indicator and body composition measurements should be considered as complementary tools. PMID:25479849

CT evaluation of timing for ossification of the medial clavicular epiphysis in a contemporary Western Australian population.

PubMed

Franklin, Daniel; Flavel, Ambika

2015-05-01

The clavicle is the first bone to ossify in the developing embryo and the last to complete epiphyseal union. It is the latter sustained period of growth that has attracted the interest of skeletal biologists and forensic practitioners alike, who collectively recognize the important opportunity this bone affords to estimate skeletal age across the prenatal to early adult lifespan. Current research is largely directed towards evaluating the applicability of assessing fusion in the medial epiphysis, specifically for determining age of majority in the living. This study aims to contribute further insights, and inform medicolegal practice, by evaluating the Schmeling five-stage system for the assessment of clavicular development in a Western Australian population. We retrospectively evaluated high-resolution multiple detector computed tomography (MDCT) scans of 388 individuals (210 male; 178 female) between 10 and 35 years of age. Scans are viewed in axial and multiplanar reconstructed (MPR) images using OsiriX®. Fusion status is scored according to a five-stage system. Transition analysis is used to calculate age ranges and determine the mean age for transition between an unfused, fusing and fused status. The maximum likelihood estimates (in years) for transition from unfused to fusing is 20.60 (male) and 19.19 (female); transition from fusing to complete fusion is 21.92 (male) and 21.47 (female). Results of the present study confirm the reliability of the assessed method and demonstrate remarkable consistency to data reported for other global populations.

Cardiovascular evaluation of middle-aged/ senior individuals engaged in leisure-time sport activities: position stand from the sections of exercise physiology and sports cardiology of the European Association of Cardiovascular Prevention and Rehabilitation.

PubMed

Borjesson, Mats; Urhausen, Alex; Kouidi, Evangelia; Dugmore, Dorian; Sharma, Sanjay; Halle, Martin; Heidbüchel, Hein; Björnstad, Hans Halvor; Gielen, Stephan; Mezzani, Alessandro; Corrado, Domenico; Pelliccia, Antonio; Vanhees, Luc

2011-06-01

Regular aerobic exercise at moderate intensities and an increased physical fitness are associated with a reduced risk of fatal and nonfatal coronary events in middle-aged individuals. In contrast, moderate and vigorous physical exertion is associated with an increased risk for cardiac events, including sudden cardiac death in individuals harbouring cardiovascular disease. The risk-benefit ratio may differ in relation to the individual’s age, fitness level, and presence of cardiovascular disease; sedentary individuals with underlying coronary artery disease are at greatest risk. The intention of the present position stand of the European Association of Cardiovascular Prevention and Rehabilitation is to encourage individuals to participate in regular physical activity and derive the benefits of physical exercise while minimizing the risk of cardiovascular adverse events. Therefore, the aim is to establish the most practical method of cardiovascular evaluation in middle-age/senior individuals, who are contemplating exercise or who are already engaged in nonprofessional competitive or recreational leisure sporting activity. These recommendations rely on existing scientific evidence, and in the absence of such, on expert consensus. The methodology of how middle-aged and older individuals should be evaluated appropriately before engaging in regular physical activity is both complex and controversial. On practical grounds the consensus panel recommend that such evaluation should vary according to the individual’s cardiac risk profile and the intended level of physical activity. Self assessment of the habitual physical activity level and of the risk factors, are recommended for screening of large populations. Individuals deemed to be at risk require further evaluation by a qualified physician. In senior/adult individuals with an increased risk for coronary events, maximal exercise testing (and possibly further evaluations) is advocated. Hopefully, the recommendations in this paper provide a practical solution for facilitating safe exercise prescription in senior/adults.

Examination of the Psychometric Properties of the Knowledge of Aging for Social Work Quiz

ERIC Educational Resources Information Center

Nakao, Kayoko C.; Damron-Rodriguez, JoAnn; Lawrance, Frances P.; Volland, Patricia J.

2013-01-01

Using graduate social work students' data ("n" = 481) in the Hartford Partnership Program for Aging Education (HPPAE) in the United States, the study examined psychometric properties of the Knowledge of Aging for Social Work Quiz (KASW), a revision of the Facts on Aging Quiz, to evaluate biopsychosocial knowledge relevant to social work.…

How Do You Know You're Old? Gender Differences in Cues Triggering the Experience of Personal Aging

ERIC Educational Resources Information Center

Panek, Paul E.; Hayslip, Bert, Jr.; Pruett, Jessica H.

2014-01-01

In order to evaluate the gender differences on the experience of aging, 142 individuals 50 years of age and older completed an interview regarding experiences with another individual conveying the message that they were "old." Interviewees were asked about the type of situation, the age and gender of the response person, and the…

Association between Self-Reported Health and Physical and/or Sexual Abuse Experienced before Age 18

ERIC Educational Resources Information Center

Bonomi, Amy E.; Cannon, Elizabeth A.; Anderson, Melissa L.; Rivara, Frederick P.; Thompson, Robert S.

2008-01-01

Objective: The present study evaluated the association between women's health and physical and sexual abuse suffered before age 18. Methods: A total of 3,568 randomly sampled insured women ages 18-64 completed a telephone interview to assess history of physical only, sexual only, or both physical and sexual abuse before age 18 (Behavioral Risk…

Interaction between age of irradiation and age of testing in the disruption of operant performance using a ground-based model for exposure to cosmic rays

USDA-ARS?s Scientific Manuscript database

Exposure to HZE particles produces deficits in cognitive performance. While previous research has shown a progressive deterioration in cognitive performance in radiated rats as a function of age, the present experiment was designed to evaluate the effects of age of irradiation independently of the ...

Age-related changes in executive control and their relationships with activity performance in handwriting.

PubMed

Rosenblum, Sara; Engel-Yeger, Batya; Fogel, Yael

2013-04-01

Deterioration in the frontal and prefrontal cortex associated with executive functions (EF) occurs with age and may be associated with changes in daily performance. The aim of the present study was to describe changes occurring with age in Executive Functions (EF) and handwriting activity, as well as to analyze relationships between age, EF and handwriting performance. The study population included 80 healthy participants (aged 31 to 76+) living in the community. After answering five questions about their writing habits, the participants completed the Behavioral Assessment of the Dysexecutive Syndrome (BADS). In addition, they performed a handwriting task on a digitizer included in the Computerized Penmanship Evaluation Tool (ComPET), which provides kinematic measures of the handwriting process. Significant differences were found between the four age groups for both EF and temporal and spatial handwriting measures. A series of regressions indicated that age predicted 35% of the variance of the BADS profile score (EF control) and 32% of the variance of in-air time while writing. The results of this study indicated age effect on both EF control and handwriting performance. Possible implications for further research and clinical evaluation and intervention are discussed. Copyright © 2013 Elsevier B.V. All rights reserved.

[Age at Onset as a Marker of Subtypes of Manic-Depressive Illness].

PubMed

Pedraza, Ricardo Sánchez; Losada, Jorge Rodríguez; Jaramillo, Luis Eduardo

2012-09-01

Age at onset of bipolar disorder has been reported as a variable that may be associated with different clinical subtypes. To identify patterns in the distributions of age at onset of bipolar disease and to determine whether age at onset is associated with specific clinical characteristics. Admixture analysis was applied to identify bipolar disorder subtypes according to age at onset. The EMUN scale was used to evaluate clinical characteristics and principal components were estimated to evaluate the relationship between subtypes according to age at onset and symptoms in the acute in the acute phase, using multivariable analyses. According to age at onset, three distributions have been found: early onset: 17.7 years (S.D. 2.4); intermediate-onset: 23.9 years (S.D. 5.6); late onset: 42.8 years (S.D. 12.1). The late-onset group is antisocial, with depressive symptoms, thinking and language disorders, and socially disruptive behaviors. In patients having bipolar disorder, age at onset is antisocial with three groups having specific clinical characteristics. Copyright © 2012 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

Sargassum fusiforme polysaccharides activate antioxidant defense by promoting Nrf2-dependent cytoprotection and ameliorate stress insult during aging.

PubMed

Chen, Peichao; He, Dan; Zhang, Ya; Yang, Shanshan; Chen, Liujun; Wang, Shengqin; Zou, Huixi; Liao, Zhiyong; Zhang, Xu; Wu, Mingjiang

2016-11-09

Aging is a complex issue, which results in a progressive decline process in cellular protection and physiological functions. Illustrating the causes of aging and pharmaceutical interference with the aging process has been a pivotal issue for thousands of years. Sargassum fusiforme (S. fusiforme), a kind of brown alga, is also named the "longevity vegetable" as it is not only a kind of food, but also used as an herb in traditional Chinese Medicine for maintaining health and treatment of thyroid disease, cardiovascular disease and so on. But how S. fusiforme promotes longevity is vastly equivocal. We got clues from S. fusiforme polysaccharides, which exhibited antioxidant activity, but the underlying mechanisms remained unclear. In this study, we evaluated the antioxidant effect and the possible mechanisms that S. fusiforme polysaccharides have against d-galactose-induced aging and chronic aging. We selected the SFPS as the candidate for antioxidant defense evaluation, which is a type of S. fusiforme polysaccharide with strong free radical scavenging activity and non-toxicity. It revealed that the antioxidant defense of the d-galactose-induced mice was markedly recovered when they were intragastrically administrated with the SFPS. However, oxidative damage may not be the only cause of aging. We further evaluated the function of the SFPS in the chronic aging mice. Intriguingly, we even found an obvious aging phenotype in the middle aged male ICR mice, which showed a significant decline in Nrf2-dependent cytoprotection. When 9-month old male ICR mice were treated with the SFPS for 2 months or even 11 months to their mean survival age, experimental measurements showed that the SFPS significantly promoted the antioxidant defense and mitochondrial integrity during aging. Furthermore, we suggest that the SFPS promotes Nrf2-dependent cytoprotection by upregulating the nuclear Nrf2 translocation, which may be mediated by p21 and JNK dependent pathways. These results suggest that the SFPS may decelerate the aging process by enhancing Nrf2-dependent cytoprotection, especially antioxidant defense.

Recent and past musical activity predicts cognitive aging variability: direct comparison with general lifestyle activities.

PubMed

Hanna-Pladdy, Brenda; Gajewski, Byron

2012-01-01

Studies evaluating the impact of modifiable lifestyle factors on cognition offer potential insights into sources of cognitive aging variability. Recently, we reported an association between extent of musical instrumental practice throughout the life span (greater than 10 years) on preserved cognitive functioning in advanced age. These findings raise the question of whether there are training-induced brain changes in musicians that can transfer to non-musical cognitive abilities to allow for compensation of age-related cognitive declines. However, because of the relationship between engagement in general lifestyle activities and preserved cognition, it remains unclear whether these findings are specifically driven by musical training or the types of individuals likely to engage in greater activities in general. The current study controlled for general activity level in evaluating cognition between musicians and nomusicians. Also, the timing of engagement (age of acquisition, past versus recent) was assessed in predictive models of successful cognitive aging. Seventy age and education matched older musicians (>10 years) and non-musicians (ages 59-80) were evaluated on neuropsychological tests and general lifestyle activities. Musicians scored higher on tests of phonemic fluency, verbal working memory, verbal immediate recall, visuospatial judgment, and motor dexterity, but did not differ in other general leisure activities. Partition analyses were conducted on significant cognitive measures to determine aspects of musical training predictive of enhanced cognition. The first partition analysis revealed education best predicted visuospatial functions in musicians, followed by recent musical engagement which offset low education. In the second partition analysis, early age of musical acquisition (<9 years) predicted enhanced verbal working memory in musicians, while analyses for other measures were not predictive. Recent and past musical activity, but not general lifestyle activities, predicted variability across both verbal and visuospatial domains in aging. These findings are suggestive of different use-dependent adaptation periods depending on cognitive domain. Furthermore, they imply that early age of musical acquisition, sustained and maintained during advanced age, may enhance cognitive functions and buffer age and education influences.

Evaluation of Crack Arrest Toughness ( K IA) of P91 Steel in Various Cold Worked and Thermally Aged Conditions

NASA Astrophysics Data System (ADS)

Sathyanarayanan, S.; Moitra, A.; Sasikala, G.; Bhaduri, A. K.

2015-02-01

K IA is increasingly being regarded as a characteristic fracture toughness below which cleavage fracture does not occur. Its evaluation from small-sized Charpy specimens would be advantageous for applications in power plant industries. In this study, K IA has been evaluated for P91 steel in various cold worked and thermally aged conditions. Evaluation of K IA requires determination of crack arrest load( P arrest) and crack arrest length( a arrest). The main challenge is in the determination of a arrest due to the non-availability of standard methodologies and the absence of unequivocal microstructural signatures on the fracture surface in this steel to identify crack arrest. a arrest has been determined using the analytical Key- Curve methodology which has proven successful for this steel in unaged condition. The applicability of the Key- Curve method is validated by the good agreement of the determined final crack length with that measured optically on unbroken specimens of N&T and subsequently 15% cold-worked P91 steel which had been previously aged at 650 °C for 5000 h. Mean K IA varies from 47.46 MPa√m (NT steel aged at 600 °C for 5000 h) to 69.85 MPa√m(NT + 15% cw steel aged at 650 °C for 10000 h) for the various cold worked and aged datasets. K IA is found to be an average property unlike initiation toughness ( K Jd) which shows statistical scatter. Mean K IA is found to be in reasonable agreement with the lower bound values of cleavage initiation toughness ( K Jd) for the datasets in this study.

A systematic review of instruments for measuring outcomes in economic evaluation within aged care.

PubMed

Bulamu, Norma B; Kaambwa, Billingsley; Ratcliffe, Julie

2015-11-09

This paper describes the methods and results of a systematic review to identify instruments used to measure quality of life outcomes in older people. The primary focus of the review was to identify instruments suitable for application with older people within economic evaluations conducted in the aged care sector. Online databases searched were PubMed, Medline, Scopus, and Web of Science, PsycInfo, CINAHL, Embase and Informit. Studies that met the following criteria were included: 1) study population exclusively above 65 years of age 2) measured health status, health related quality of life or quality of life outcomes more broadly through use of an instrument developed for this purpose, 3) used a generic preference based instrument or an older person specific preference based or non-preference based instrument or both, and 4) published in journals in the English language after 2000. The most commonly applied generic preference based instrument in both the community and residential aged care context was the EuroQol - 5 Dimensions (EQ-5D), followed by the Adult Social Care Outcomes Toolkit (ASCOT) and the Health Utilities Index (HUI2/3). The most widely applied older person specific instrument was the ICEpop CAPability measure for Older people (ICECAP-O) in both community and residential aged care. In the absence of an ideal instrument for incorporating into economic evaluations in the aged care sector, this review recommends the use of a generic preference based measure of health related quality of life such as the EQ-5D to obtain quality adjusted life years, in combination with an instrument that has a broader quality of life focus like the ASCOT, which was designed specifically for evaluating interventions in social care or the ICECAP-O, a capability measure for older people.

[Establish Assessment Model of 18 Years of Age in Chinese Han Population by Mandibular Third Molar].

PubMed

Fan, Fei; Dai, Xin-hua; Wang, Liang; Li, Yuan; Zhang, Kui; Deng, Zhen-hua

2016-02-01

To explore the value of estimating chronologic age based on the grades of mandibular third molar development. To evaluate whether mandibular third molar could be used as an indicator for estimating the age under or over 18 years. The mineralization status of mandibular third molar of 1 845 individuals aged 10 - 30 was graded and marked based on Demirjian's classification of grades reformed by Orhan. Gender difference was examined by t-test. A cubic regression model was established to analyze the correlation between third molar and chronologic age. Each grade of age cumulative distribution diagram and ROC curve was respectively performed to evaluate the relationship between third molar and the age of 18. Using Bayes discriminant analysis, an equation was established for estimating the age of 18. The inner-rater reliability was 0.903. Statistical analysis showed a moderate correlation between age and grade. Significant differences of both genders were found only in grade D and H (P < 0.05). Males at the grades from 1 to D and females at the grades from 1 to C were under 18 years old, and both males and females at grade H were over 18 years old. The area under the ROC curve was 0.797 (P < 0.05). Third molar development shows a high correlation with age, and combined with other indicators, it can be used to estimate the age of 18.

Epicatechin as a Therapeutic Strategy to Mitigate the Development of Cardiac Remodeling and Fibrosis

DTIC Science & Technology

2017-09-01

Currently, no drugs target HFpEF and the development of animal models can assist in therapy evaluation. We developed a female rat model of aging...allocated into an aging group, aging + ovariectomy and aging + ovariectomy + 10% fructose in drinking water. At 22 months of age, animals were...epicatechin (Epi) will ameliorate adverse tissue remodeling and cardiac fibrosis in female animal models developing diastolic dysfunction as seen in women

Mated Progeny Production Is a Biomarker of Aging in Caenorhabditis elegans

PubMed Central

Pickett, Christopher L.; Dietrich, Nicholas; Chen, Junfang; Xiong, Chengjie; Kornfeld, Kerry

2013-01-01

The relationships between reproduction and aging are important for understanding the mechanisms of aging and evaluating evolutionary theories of aging. To investigate the effects of progeny production on reproductive and somatic aging, we conducted longitudinal studies of Caenorhabditis elegans hermaphrodites. For mated wild-type animals that were not sperm limited and survived past the end of the reproductive period, high levels of cross-progeny production were positively correlated with delayed reproductive and somatic aging. In this group of animals, individuals that generated more cross progeny also reproduced and lived longer than individuals that generated fewer cross progeny. These results indicate that progeny production does not accelerate reproductive or somatic aging. This longitudinal study demonstrated that cumulative cross progeny production through day four is an early-stage biomarker that is a positive predictor of longevity. Furthermore, in mated animals, high levels of early cross progeny production were positively correlated with high levels of late cross progeny production, indicating that early progeny production does not accelerate reproductive aging. The relationships between progeny production and aging were further evaluated by comparing self-fertile hermaphrodites that generated relatively few self progeny with mated hermaphrodites that generated many cross progeny. The timing of age-related somatic degeneration was similar in these groups, suggesting progeny production does not accelerate somatic aging. These studies rigorously define relationships between progeny production, reproductive aging, and somatic aging and identify new biomarkers of C. elegans aging. These results indicate that some mechanisms or pathways control age-related degeneration of both reproductive and somatic tissues in C. elegans. PMID:24142929

Analysis of Muscle Force-Velocity Parameter Changes in Elderly Women Resulting from Physical Activity--In Continuous Examinations

ERIC Educational Resources Information Center

Skrzek, Anna; Stefanska, Malgorzata

2012-01-01

The aim of the paper was to evaluate changes in muscle force-velocity parameters (F-v) in elderly women subjected to physical exercise. The examinations encompassed 20 women, aged 62-71, who were students at the University of the Third Age in Wroclaw. The evaluation of flexors and extensors of the knee joint, as well as flexors and extensors of…

Evaluation of Visual Pedagogy in Dental Check-Ups and Preventive Practices among 6-12-Year-Old Children with Autism

ERIC Educational Resources Information Center

Nilchian, Firoozeh; Shakibaei, Fereshteh; Jarah, Zeinab Taghi

2017-01-01

This study was aimed to evaluate the impact of visual pedagogy in dental check-ups and preventive practices among children with autism aged 6-12. In this randomized double-blind clinical trial, the cooperation of 40 children with autism age 6-12. The selected children were equally divided into two groups of case and control (n = 20). The obtained…

Evaluation of an Intensive Intervention Programme to Protect Children Aged 1-5 Years from Environmental Tobacco Smoke Exposure at Home in Turkey

ERIC Educational Resources Information Center

Yücel, U.; Öcek, Z. A.; Çiçeklioglu, M.

2014-01-01

The aim of this randomized-controlled trial was to evaluate the effectiveness of an intensive intervention to reduce children's environmental tobacco smoke (ETS) exposure at their home compared with a minimal intervention. The target population of the study was the mothers of children aged 1-5 who lived in the Cengizhan district of Izmir in…

Designing Playful Learning by Using Educational Board Game for Children in the Age Range of 7-12: (A Case Study: Recycling and Waste Separation Education Board Game)

ERIC Educational Resources Information Center

Mostowfi, Sara; Mamaghani, Nasser Koleini; Khorramar, Mehdi

2016-01-01

Due to a progressive deterioration of our planet and its resources, environmental education has become important and children are required to understand environmental issues at an early ages. So, they can cultivate the positive changes in the future. Over the past decade, many new evaluation methods have developed for evaluating user experience…

EDI OCT evaluation of choroidal thickness in Stargardt disease

PubMed Central

Sodi, Andrea; Bacherini, Daniela; Caporossi, Orsola; Murro, Vittoria; Mucciolo, Dario Pasquale; Cipollini, Francesca; Passerini, Ilaria; Virgili, Gianni; Rizzo, Stanislao

2018-01-01

Purpose Choroidal thickness (CT) evaluation with EDI-OCT in Stargardt Disease (STGD), considering its possible association with some clinical features of the disease. Methods CT was evaluated in 41 STGD patients and in 70 controls. Measurements were performed in the subfoveal position and at 1000 μm nasally and temporally. CT average values in STGD and in the control group were first compared by means of Student’s T test. Then, the possible association between CT and some clinical features was evaluated by means of linear regression analysis. Considered clinical parameters were: age, age on onset, duration of the disease, visual acuity, foveal thickness, Fishman clinical phenotype, visual field loss and ERG response. Results Average CT was not significantly different between controls and STGD patients. In the STGD group the correlation between CT and age (r = 0.22, p = 0.033) and age of onset (r = 0.05, p = 0.424) was modest, while that of CT with disease duration (r = 0.30, p<0.001) was moderate. CT and foveal thickness were also significantly but modestly correlated (r = 0.15, p = 0.033). Conclusion In our series average CT is not significantly changed in STGD in comparison with the controls. Nevertheless a choroidal thinning may be identified in the more advanced stages of the disease. PMID:29304098

Short physical performance battery for middle-aged and older adult cardiovascular disease patients: implication for strength tests and lower extremity morphological evaluation.

PubMed

Yasuda, Tomohiro; Fukumura, Kazuya; Nakajima, Toshiaki

2017-04-01

[Purpose] To examine if the SPPB is higher with healthy subjects than outpatients, which was higher than inpatients and if the SPPB can be validated assessment tool for strength tests and lower extremity morphological evaluation in cardiovascular disease patients. [Subjects and Methods] Twenty-four middle aged and older adults with cardiovascular disease were recruited from inpatient and outpatient facilities and assigned to separate experimental groups. Twelve age-matched healthy volunteers were assigned to a control group. SPPB test was used to assess balance and functional motilities. The test outcomes were compared with level of care (inpatient vs. outpatient), physical characteristics, strength and lower extremity morphology. [Results] Total SPPB scores, strength tests (knee extensor muscle strength), and lower extremity morphological evaluation (muscle thickness of anterior and posterior mid-thigh and posterior lower-leg) were greater in healthy subjects and outpatients groups compared with inpatients. To predict total Short Physical Performance Battery scores, the predicted knee extension and anterior mid-thigh muscle thickness were calculated. [Conclusion] The SPPB is an effective tool as the strength tests and lower extremity morphological evaluation for middle-aged and older adult cardiovascular disease patients. Notably, high knee extensor muscle strength and quadriceps femoris muscle thickness are positively associated with high SPPB scores.

Development of facial sexual dimorphism in children aged between 12 and 15 years: a three-dimensional longitudinal study.

PubMed

Koudelová, J; Brůžek, J; Cagáňová, V; Krajíček, V; Velemínská, J

2015-08-01

To evaluate sexual dimorphism of facial form and shape and to describe differences between the average female and male face from 12 to 15 years. Overall 120 facial scans from healthy Caucasian children (17 boys, 13 girls) were longitudinally evaluated over a 4-year period between the ages of 12 and 15 years. Facial surface scans were obtained using a three-dimensional optical scanner Vectra-3D. Variation in facial shape and form was evaluated using geometric morphometric and statistical methods (DCA, PCA and permutation test). Average faces were superimposed, and the changes were evaluated using colour-coded maps. There were no significant sex differences (p > 0.05) in shape in any age category and no differences in form in the 12- and 13-year-olds, as the female faces were within the area of male variability. From the age of 14, a slight separation occurred, which was statistically confirmed. The differences were mainly associated with size. Generally boys had more prominent eyebrow ridges, more deeply set eyes, a flatter cheek area, and a more prominent nose and chin area. The development of facial sexual dimorphism during pubertal growth is connected with ontogenetic allometry. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

[Anthropometric growth of the school population in rural and suburban areas of Durango, Mexico].

PubMed

Tena-Flores, J A; Frisancho, A R

1997-06-01

The nutritional status of school children from the rural and suburban areas from the state of Durango. México, was determined using anthropometric evaluation, during the periods 92-93 and 93-94. The sample included a total of 1,033 school children, of which 504 were males and 529 females, ranging ages from 3 to 15 years. The results of the study indicate that compared to the international standards, linear growth and weight of the Durango children decline with age and accentuate theirself through time. On the other hand, growth in body mass index exhibits a lesser retardation than that of height by age and weight by age. Evaluation of the weight by height index indicated that about 3% of the school children has suffered from chronic undernutrition.

Cancer Surgery in the Elderly

PubMed Central

Kowdley, Gopal C.; Merchant, Nishant; Richardson, James P.; Somerville, Justin; Gorospe, Myriam; Cunningham, Steven C.

2012-01-01

The proportions both of elderly patients in the world and of elderly patients with cancer are both increasing. In the evaluation of these patients, physiologic age, and not chronologic age, should be carefully considered in the decision-making process prior to both cancer screening and cancer treatment in an effort to avoid ageism. Many tools exist to help the practitioner determine the physiologic age of the patient, which allows for more appropriate and more individualized risk stratification, both in the pre- and postoperative periods as patients are evaluated for surgical treatments and monitored for surgical complications, respectively. During and after operations in the oncogeriatric populations, physiologic changes occuring that accompany aging include impaired stress response, increased senescence, and decreased immunity, all three of which impact the risk/benefit ratio associated with cancer surgery in the elderly. PMID:22272172

Language development and everyday functioning of children with hearing loss assessed at 3 years of age.

PubMed

Ching, Teresa Y C; Crowe, Kathryn; Martin, Vivienne; Day, Julia; Mahler, Nicole; Youn, Samantha; Street, Laura; Cook, Cassandra; Orsini, Julia

2010-04-01

This paper reports language ability and everyday functioning of 133 children with hearing impairment who were evaluated at 3 years of age, as part of the Longitudinal Outcomes of Children with Hearing Impairment (LOCHI) study. The language abilities of children were evaluated using the Preschool Language Scale (PLS-4), Peabody Picture Vocabulary Test (PPVT), Diagnostic Evaluation of Articulation and Phonology (DEAP) and Child Development Inventory (CDI). Everyday functioning of children was evaluated by interviewing parents using the Parents' Evaluation of Aural/oral performance of Children (PEACH) questionnaire. There were significant correlations among language measures, and also between the standardized language measures and the PEACH. On average, children who had language deficits exhibited difficulties in everyday functioning. The evidence lends support to a systematic use of parents' observations to evaluate communicative functioning of children in real life. On average, children's language attainment decreased as hearing loss increased, more so for children of less highly educated parents. Factors that were not significantly associated with speech and language outcomes at 3 years were age of amplification and socioeconomic status. As multiple factors affect children's outcomes, it will be possible to examine their effects on outcomes of children when all data in the LOCHI study are available.

Myopia Stabilization and Associated Factors Among Participants in the Correction of Myopia Evaluation Trial (COMET)

PubMed Central

2013-01-01

Purpose. To use the Gompertz function to estimate the age and the amount of myopia at stabilization and to evaluate associated factors in the Correction of Myopia Evaluation Trial (COMET) cohort, a large ethnically diverse group of myopic children. Methods. The COMET enrolled 469 ethnically diverse children aged 6 to younger than 12 years with spherical equivalent refraction between −1.25 and −4.50 diopters (D). Noncycloplegic refraction was measured semiannually for 4 years and annually thereafter. Right eye data were fit to individual Gompertz functions in participants with at least 6 years of follow-up and at least seven refraction measurements over 11 years. Function parameters were estimated using a nonlinear least squares procedure. Associated factors were evaluated using linear regression. Results. In total, 426 participants (91%) had valid Gompertz curve fits. The mean (SD) age at myopia stabilization was 15.61 (4.17) years, and the mean (SD) amount of myopia at stabilization was −4.87 (2.01) D. Ethnicity (P < 0.0001) but not sex or the number of myopic parents was associated with the age at stabilization. Ethnicity (P = 0.02) and the number of myopic parents (P = 0.01) but not sex were associated with myopia magnitude at stabilization. At stabilization, African Americans were youngest (mean age, 13.82 years) and had the least myopia (mean, −4.36 D). Participants with two versus no myopic parents had approximately 1.00 D more myopia at stabilization. The age and the amount of myopia at stabilization were correlated (r = −0.60, P < 0.0001). Conclusions. The Gompertz function provides estimates of the age and the amount of myopia at stabilization in an ethnically diverse cohort. These findings should provide guidance on the time course of myopia and on decisions regarding the type and timing of interventions. PMID:24159085

Reliability of third molar development for age estimation in Gujarati population: A comparative study.

PubMed

Gandhi, Neha; Jain, Sandeep; Kumar, Manish; Rupakar, Pratik; Choyal, Kanaram; Prajapati, Seema

2015-01-01

Age assessment may be a crucial step in postmortem profiling leading to confirmative identification. In children, Demirjian's method based on eight developmental stages was developed to determine maturity scores as a function of age and polynomial functions to determine age as a function of score. Of this study was to evaluate the reliability of age estimation using Demirjian's eight teeth method following the French maturity scores and Indian-specific formula from developmental stages of third molar with the help of orthopantomograms using the Demirjian method. Dental panoramic tomograms from 30 subjects each of known chronological age and sex were collected and were evaluated according to Demirjian's criteria. Age calculations were performed using Demirjian's formula and Indian formula. Statistical analysis used was Chi-square test and ANOVA test and the P values obtained were statistically significant. There was an average underestimation of age with both Indian and Demirjian's formulas. The mean absolute error was lower using Indian formula hence it can be applied for age estimation in present Gujarati population. Also, females were ahead of achieving dental maturity than males thus completion of dental development is attained earlier in females. Greater accuracy can be obtained if population-specific formulas considering the ethnic and environmental variation are derived performing the regression analysis.

Study of the Influence of Age in 18F-FDG PET Images Using a Data-Driven Approach and Its Evaluation in Alzheimer's Disease.

PubMed

Jiang, Jiehui; Sun, Yiwu; Zhou, Hucheng; Li, Shaoping; Huang, Zhemin; Wu, Ping; Shi, Kuangyu; Zuo, Chuantao; Neuroimaging Initiative, Alzheimer's Disease

2018-01-01

18 F-FDG PET scan is one of the most frequently used neural imaging scans. However, the influence of age has proven to be the greatest interfering factor for many clinical dementia diagnoses when analyzing 18 F-FDG PET images, since radiologists encounter difficulties when deciding whether the abnormalities in specific regions correlate with normal aging, disease, or both. In the present paper, the authors aimed to define specific brain regions and determine an age-correction mathematical model. A data-driven approach was used based on 255 healthy subjects. The inferior frontal gyrus, the left medial part and the left medial orbital part of superior frontal gyrus, the right insula, the left anterior cingulate, the left median cingulate, and paracingulate gyri, and bilateral superior temporal gyri were found to have a strong negative correlation with age. For evaluation, an age-correction model was applied to 262 healthy subjects and 50 AD subjects selected from the ADNI database, and partial correlations between SUVR mean and three clinical results were carried out before and after age correction. All correlation coefficients were significantly improved after the age correction. The proposed model was effective in the age correction of both healthy and AD subjects.

Augmentation of ferulic acid-induced vasorelaxation with aging and its structure importance in thoracic aorta of spontaneously hypertensive rats.

PubMed

Fukuda, Toshihiko; Kuroda, Takahiro; Kono, Miki; Hyoguchi, Mai; Tanaka, Mitsuru; Matsui, Toshiro

2015-10-01

Aging deteriorates vascular functions such as vascular reactivity and stiffness. Thus far, various reports suggest that bioactive compounds can improve vascular functions. However, few age-related studies of natural bioactive compounds are available. The present study attempted to evaluate age-related vasorelaxation of bioactive cinnamic acids, caffeic acid, and ferulic acid using aged rat thoracic aorta. Vasorelaxation was evaluated in thoracic aorta from both 8, 18, and 40 weeks old Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) respectively. The result indicated that caffeic acid possessed the vasorelaxation regardless of aging in WKY and SHR. Moreover, the vasorelaxation of ferulic acid enhanced with aging in SHR. The vasorelaxation behavior was acted in an endothelium-independent manner. To access structure importance of enhanced vasorelaxation, analogues of ferulic acid were tested. In 40 weeks old SHR, 3,4-dimethoxycinnamic acid and coniferyl alcohol exhibited equivalent vasorelaxation activity with ferulic acid, providing the structural importance of methoxy-modified 3-position on the phenyl ring and 2-propenoic moiety. These results firstly demonstrated that enhanced vasorelaxation of ferulic acid with aging and 3,4-dimethoxycinnamic acid and coniferyl alcohol, along with ferulic acid, might exhibit the therapeutic potential of vasoactive power with aging.

NAPR: a Cloud-Based Framework for Neuroanatomical Age Prediction.

PubMed

Pardoe, Heath R; Kuzniecky, Ruben

2018-01-01

The availability of cloud computing services has enabled the widespread adoption of the "software as a service" (SaaS) approach for software distribution, which utilizes network-based access to applications running on centralized servers. In this paper we apply the SaaS approach to neuroimaging-based age prediction. Our system, named "NAPR" (Neuroanatomical Age Prediction using R), provides access to predictive modeling software running on a persistent cloud-based Amazon Web Services (AWS) compute instance. The NAPR framework allows external users to estimate the age of individual subjects using cortical thickness maps derived from their own locally processed T1-weighted whole brain MRI scans. As a demonstration of the NAPR approach, we have developed two age prediction models that were trained using healthy control data from the ABIDE, CoRR, DLBS and NKI Rockland neuroimaging datasets (total N = 2367, age range 6-89 years). The provided age prediction models were trained using (i) relevance vector machines and (ii) Gaussian processes machine learning methods applied to cortical thickness surfaces obtained using Freesurfer v5.3. We believe that this transparent approach to out-of-sample evaluation and comparison of neuroimaging age prediction models will facilitate the development of improved age prediction models and allow for robust evaluation of the clinical utility of these methods.

Storytelling as an age-dependent skill: oral recall of orally presented stories.

PubMed

Mergler, N L; Faust, M; Goldstein, M D

During experiment 1, three taped prose passages read by college student, middle-aged, or old tellers were orally recalled by college students in an incidental memory paradigm. More story units were remembered as the age of the teller increased (r = +.642, p less than .05). Comparison of these results, with prior research using written, as opposed to oral, presentation and recall of these stories, showed no differences in specific story units remembered. Teller age predicted recall on the two "storied" passages. These passages elicited more favorable comments from listeners when read by older tellers. The third, descriptive passage was less favorably regarded by listeners hearing older tellers. During experiment 2, taped storied passages read by middle-aged tellers were falsely attributed to young, middle-aged, or old persons before the college students listened. Incidental recall did not show an age of teller effect in this case, but the listener's evaluation of the speaker exhibited age-dependent stereotypes. It was concluded that 1) physical qualities of older voices lead to more effective oral transmission; 2) that one expects to receive certain types of oral information from older persons; and 3) that a mismatch between physical vocal quality and age attribution effects evaluation of the speaker, not recall of the information.

Teacher Evaluations of Executive Functioning in Schoolchildren Aged 9-12 and the Influence of Age, Sex, Level of Parental Education.

PubMed

van Tetering, Marleen A J; Jolles, Jelle

2017-01-01

Executive functions (EFs) develop over the period of early childhood and adolescence up until young adulthood. Individual children differ substantially in the pace at which their EFs develop, and characteristics such as sex and the level of parental education (LPE) are thought to contribute to these differences. In the present study, we assessed age-related changes in EFs as perceived and evaluated by teachers and parents as well as the influence of sex and LPE on their evaluations. We used a newly developed observer-report questionnaire, the Amsterdam Executive Function Inventory (AEFI). The AEFI assesses three important components of the executive aspects of daily life behavior in 13 questions: Attention; Self-control and Self-monitoring; and Planning and Initiative taking. Teachers and parents evaluated these aspects of executive functioning in 186 schoolchildren in grades 3-6 (age: 9-12 years). Age effects within grades and differences in social economic status between the four participating schools were controlled. Results showed a significant increase in teacher-perceived EFs from third to fourth grades and from fifth to sixth grades. This development was influenced both by the sex of the child and by the LPE. As perceived by teachers, the component self-control and self-monitoring was higher for girls than for boys, and planning abilities were higher for children from families with a higher LPE. Additional analyses showed that there is a systematic and statistically significant difference between the evaluations of the teachers and that of parents. Parents reported higher scores for planning, whereas teachers reported higher scores for self-control and self-monitoring. Evaluations by parents and teachers were different for girls, but not for boys. These findings are important because they imply that the development of EFs as perceived by parents and teachers is influenced by child-related factors. Second, there are clear differences in evaluations between teachers and parents. The AEFI appears to be a tool that is easily used by parents and teachers and shows potential for monitoring the development of EFs as perceived by significant others during young adolescence.

Evaluating RNAlater® as a preservative for using near-infrared spectroscopy to predict Anopheles gambiae age and species

USDA-ARS?s Scientific Manuscript database

Mosquito age and species identification is a crucial determinant of the efficacy of vector control programs. Near-infrared spectroscopy (NIRS) has previously been applied successfully to rapidly, non-destructively, and simultaneously determine the age and species of freshly anesthetized African mala...

Size for Gestational Age and Neonatal Temperament.

ERIC Educational Resources Information Center

Riese, Marilyn L.

The appropriate-for-gestational-age (AGA) and small-for-gestational-age (SGA) infants from 30 pairs of full-term and 15 pairs of preterm same-sex twins were compared for neonatal temperament. The evaluation of neonatal temperament included ratings of irritability, resistance to soothing, activity level, reactivity, and reinforcement value. Results…

(CALIFORNIA) META-ANALYSIS OF THE LIFE STYLE FACTORS RELEVANT TO ENVIRONMENTAL HAZARDS FOR THE AGING POPULATION

EPA Science Inventory

The goal of this U.S. Environmental Protection Agency (EPA) Aging Initiative study is to characterize activity patterns, physiological changes, and environmental exposures for the aging population. Meta-analysis was performed on more than 2000 reviewed articles to evaluate the l...

The Leadership Institute for Active Aging: A Volunteer Recruitment and Retention Model.

ERIC Educational Resources Information Center

Wilson, Laura; Steele, Jack; Thompson, Estina; D'heron, Cathy

2002-01-01

The Leadership Institute for Active Aging, an approach to recruiting and retaining volunteers over 50, provides training focused on community resources, aging, self-worth, and volunteering and internships in community-based organizations involving health and social services. Exit interviews and program evaluations affirmed that the leadership…

Handbook of Aging and the Social Sciences.

ERIC Educational Resources Information Center

Binstock, Robert H., Ed.; Shanas, Ethel

This is the first of three volumes which comprise a review of the social, psychological, and biological aspects of aging. This volume organizes, evaluates, and interprets research data, concepts, theories, and issues in aging from the perspectives of the various social sciences. Intended for use by researchers, professional practitioners,…

77 FR 33475 - National Institute On Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-06

...; Stress and Aging. Date: July 9, 2012. Time: 9:00 a.m. to 1:00 p.m. Agenda: To review and evaluate grant... Panel; Health, Sex, and Aging. Date: July 18, 2012. Time: 1:00 p.m. to 5:00 p.m. Agenda: To review and...

Physical Attractiveness, Age, and Sex as Determinants of Reactions to Resumes.

ERIC Educational Resources Information Center

Quereshi, M. Y.; Kay, Janet P.

1986-01-01

Physical attractiveness, age, and sex were manipulated to determine their effect on the evaluation of 54 hypothetical applicants' resumes for three different jobs by 60 Master's in Business Administration students. Physical attractiveness favorably influenced the suitability ratings for all jobs; raters' sex and age were not significant but…

Long bone robustness during growth: A cross-sectional pQCT examination of children and young adults aged 5-29years.

PubMed

Rantalainen, Timo; Weeks, Benjamin K; Nogueira, Rossana C; Beck, Belinda R

2016-12-01

Skeletal robustness (cross-section size relative to length) is associated with stress fractures in adults, and appears to explain the high incidence of distal radius fractures in adolescents. However, little is known about the ontogeny of long bone robustness during the first three decades of life. Therefore, we explored the ontogeny of tibial, fibular, ulnar and radial robustness in a cross-sectional sample of 5 to 29year-old volunteers of both sexes. Peripheral quantitative computed tomography (pQCT) was used to evaluate cross-sections of the leg (4%, 14%, 38% and 66%), and forearm (4%, and 66%) in N=432 individuals. Robustness was evaluated as the total bone area divided by bone length. Differences between age-groups, sexes, and age-group×sex interactions were evaluated with ANOVA with Tukey's post hocs where appropriate. Most bone sites exhibited more robust bones in men than women (P<0.001 to 0.02), and in older age-groups than younger (P<0.001). Sex×age-group interaction was observed at the 66% and 38% tibia sites with robustness increasing more with age in men than in women (P=0.006 to 0.042). Post-hoc analyses indicated no sex differences prior to 13years-of-age, and notable exceptions to increasing robustness with age at the 4% radial and 66% tibial sites, which exhibited reduced robustness in age groups close to peak height velocity. In conclusion, the present results suggest that very little sexual dimorphism in long bone robustness exists prior to puberty, and that divergence occurs primarily after cessation of longitudinal growth. A period of relative diaphyseal slenderness was identified at age-groups coinciding with the adolescent growth spurt, which may be related to the relatively high incidence of frank and stress fracture in adolescents. Copyright © 2016 Elsevier Inc. All rights reserved.

The Evaluation of Reading Performance with Minnesota Low Vision Reading Charts in Patients with Age-related Macular Degeneration.

PubMed

Altinbay, Deniz; Adibelli, Fatih Mehmet; Taskin, Ibrahim; Tekin, Adil

2016-01-01

To evaluate the reading performance using the Minnesota low vision reading (MNREAD) charts, of patients with age-related macular degeneration (AMD) who use low vision aid (LVA) devices. This prospective study enrolled 27 patients with AMD. Distance visual acuity (VA) was evaluated with a distance chart designed for patients with low vision. Near vision and reading performance were evaluated with the Turkish version of the MNREAD charts. Unaided vision and vision with LVA devices and high spherical add near glasses was measured. P <0.05 was considered statistically significant. The mean unaided near VA was 1.05 ± 0.27 log of the minimum angle of resolution (LogMAR). The mean VA with the LVA devices was 0.71 ± 0.41 LogMAR. Reading acuity ranged between 1.15 and 0.21 LogMAR, critical print size was between - 1.2 and 0.2 LogMAR. Maximum reading speeds were between 0 and 103 words/min. The cases are divided into groups in terms of reading speed according to age, gender, diagnosis, and education. Reading speed was negatively correlated to increasing age. MNREAD reading charts can be used to evaluate reading performance in patients with AMD with low vision. The outcomes of the present study indicate that optical correction is adequate for near VA requirements in this patient population. However, optical correction was inadequate for improving reading performance. Appropriate rehabilitation programs can be used to increase reading speed.

Lifetime risk of renal replacement therapy in Europe: a population-based study using data from the ERA-EDTA Registry.

PubMed

van den Brand, Jan A J G; Pippias, Maria; Stel, Vianda S; Caskey, Fergus J; Collart, Frederic; Finne, Partik; Heaf, James; Jais, Jean-Philippe; Kramar, Reinhard; Massy, Ziad A; De Meester, Johan; Traynor, Jamie P; Reisæter, Anna Varberg; Wetzels, Jack F M; Jager, Kitty J

2017-02-01

Upcoming KDIGO guidelines for the evaluation of living kidney donors are expected to move towards a personal risk-based evaluation of potential donors. We present the age and sex-specific lifetime risk of renal replacement therapy (RRT) for end-stage renal disease in 10 European countries. We defined lifetime risk of RRT as the cumulative incidence of RRT up to age 90 years. We obtained RRT incidence rates per million population by 5-year age groups and sex using data from the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, and used these to estimate the cumulative incidence of RRT, adjusting for competing mortality risk. Lifetime risk of RRT varied from 0.44% to 2.05% at age 20 years and from 0.17% to 1.59% at age 70 years across countries, and was twice as high in men as in women. Lifetime RRT risk decreased with age, ranging from an average of 0.77% to 0.44% in 20- to- 70-year-old women, and from 1.45% to 0.96% in 20- to- 70-year-old men. The lifetime risk of RRT increased slightly over the past decade, more so in men than in women. However, it appears to have stabilized or even decreased slightly in more recent years. The lifetime risk of RRT decreased with age, was lower in women as compared with men of equal age and varied considerably throughout Europe. Given the substantial differences in lifetime risk of RRT between the USA and Europe, country-specific estimates should be used in the evaluation and communication of the risk of RRT for potential living kidney donors. © The Author 2016. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Cross-sectional analysis of penile length in males 13 to 15 years old according to pubertal development stages.

PubMed

Soydan, Hasan; Akyol, İlker; Ates, Ferhat; Yilmaz, Omer; Dursun, Furkan; Baykal, Kadir

2012-10-01

Genital development is affected by pubertal process to a great extent, and puberty is a complex phenomenon that is influenced by multiple factors resulting in individual differences. We studied penile length and its relationship to pubertal stage in boys 13 to 15 years old. Healthy boys who were candidates for military high school were evaluated between June and July 2011. Age, residence and body mass index were recorded. Stretched penile length was measured. Pubic hair was assessed according to Tanner and Marshall staging. Genital puberty stage was defined by measurement of testicular volume with Prader orchidometer. Relationship of penile length to age, residence, pubertal stages and body mass index was evaluated statistically. A total of 1,539 boys were included in the study. Mean ages and number of patients according to genital stage were as follows. Mean age was 14 years for genital stage 1 (5 patients), 13.9 years (range 13 to 15) for stage 2 (194), 14.07 years (13 to 15) for stage 3 (965) and 14.11 years (13 to 15) for stage 4 (375). Linear regression analysis revealed a significant effect of body mass index, genital stage and pubic hair stage on penile length (p <0.001) but no significant effect of age or residence. Mean penile length was significantly different among different age groups and among pubertal stages. However, mean penile lengths of different age groups within the same pubertal stage were similar. Penile length during puberty should be evaluated individually according to the current pubertal stage. Our study offers a reliable reference table of penile length for pubertal age group. Copyright © 2012 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Evaluation of peripheral lymphadenopathy with excisional biopsy: six-year experience.

PubMed

Özkan, Esra Akyüz; Göret, Ceren Canbey; Özdemir, Zeynep Tuba; Yanık, Serdar; Göret, Nuri Emrah; Doğan, Meryem; Cihan, Fatma Gökşin; Akkoca, Ayşe Neslin

2015-01-01

Lymphadenopathy (LAP) may be the first symptom of many diseases. We aimed to investigate peripheral LAP results taken by excisional biopsy. Histopathological examination of 185 lymph node biopsy specimens were evaluated between January 2009 and April 2015 in Istanbul Private Ekin Pathology Laboratory, retrospectively. The average age of patients ranged from 1 to 86 was 41.01 ± 20.62 years. 87 of were female, 98 of male. 62 (33.5%) of excisional biopsy materials were benign lesions and 123 (66.5%) of malignant. Benign lesions were consisted of reactive hyperplasia, cat-scratch disease, toxoplasmosis, necrotizing/non-necrotizing granulomatous. Of these patients, 40 had nodes with reactive hyperplasia (15 female/25 male, mean age: 27.35 y), 14 had necrotizing granulomatous disease (9 female/5 male, mean age: 39.86 y), 2 non-necrotizing granulomatous disease (1 female/1 male mean age: 43 y), 4 had cat-scratch disease (1 female/3 male mean age: 54.25 y), 1 toxoplasmosis (26 y, female), 1 Kikuchi disease (25 y, female). In the evaluation of malign lesions; 38 were Hodgkin lymphoma (HL) (20.5%, 17 female/21 male, mean age: 34.89 y) 77 had non-Hodgkin lymphoma (NHL) (41.6%, 37 female/40 male, mean age: 52.26 y), 8 metastasis (4.3%, 5 female/3 male, mean age: 53.5 y). Reactive LAP observed most common in cervical region, NHL in axillary-abdomen-inguinal-mediastinum and HL in the supraclavicular region. Excisional biopsy can be applied safely with minimal morbidity and mortality and a gold standard diagnostic method for LAP. Although LAP is mostly related with benign lesions, malignancy should be kept in mind in differential diagnosis.

Effect of intra-oral aging on t→m phase transformation, microstructure, and mechanical properties of Y-TZP dental ceramics.

PubMed

Miragaya, Luciana Meireles; Guimarães, Renato Bastos; Souza, Rodrigo Othávio de Assunção E; Santos Botelho, Glauco Dos; Antunes Guimarães, José Guilherme; da Silva, Eduardo Moreira

2017-08-01

The aim of the present study was to evaluate the influence of intra-oral aging on the tetragonal-to-monoclinic (t→m) phase transformation of two Y-TZP dental ceramics - Lava Frame (Frame) and Lava Plus (Plus) - and determine the impact of this response on their microstructures and mechanical properties: flexural strength, Young's modulus, microhardness and fracture toughness. Standardized ceramic specimens were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM) and atomic force microscopy (AFM). After the baseline analysis, the specimens were attached to personalized intra-oral resin appliances and exposed to the oral cavity of 20 subjects for 60 days and then analyzed again. Specimens produced for mechanical properties evaluation were also analyzed before and after the 60-day intra-oral aging. The data were analyzed using two-way ANOVA and Tukey HSD's post hoc test (α=0.05). Weibull analysis was used to evaluate the strength reliability. Both Y-TZP ceramics suffered t→m phase transformation after 60-day intra-oral aging (Plus=4.7%/Frame=7.7%). SEM and AFM analyses showed dislodgement of ZrO 2 grains and a significant increase in roughness after intra-oral aging for both ceramics. Both Y-TZP ceramics suffered a decrease on flexural strength, Young's modulus and fracture toughness after intra-oral aging (p<0.05). Only Plus presented a decrease of microhardness after intra-oral aging (p<0.05). Intra-oral aging for 60 days produced t→m phase transformation, changed the microstructure and decreased the mechanical properties of two Y-TZP dental ceramics. Copyright © 2017 Elsevier Ltd. All rights reserved.

Preparing the workforce for healthy aging programs: the Skills for Healthy Aging Resources and Programs (SHARP) model.

PubMed

Frank, Janet C; Altpeter, Mary; Damron-Rodriguez, JoAnn; Driggers, Joann; Lachenmayr, Susan; Manning, Colleen; Martinez, Dana M; Price, Rachel M; Robinson, Patricia

2014-10-01

Current public health and aging service agency personnel have little training in gerontology, and virtually no training in evidence-based health promotion and disease management programs for older adults. These programs are rapidly becoming the future of our community-based long-term care support system. The purpose of this project was to develop and test a model community college career technical education program, Skills for Healthy Aging Resources and Programs (SHARP), for undergraduate college students, current personnel in aging service and community organizations, and others interested in retraining. A multidisciplinary cross-sector team from disciplines of public health, sociology, gerontology and nursing developed four competency-based courses that focus on healthy aging, behavior change strategies, program management, an internship, and an option for leader training in the Chronic Disease Self-Management Program. To enhance implementation and fidelity, intensive faculty development training was provided to all instructors and community agency partners. Baseline and postprogram evaluation of competencies for faculty and students was conducted. Process evaluation for both groups focused on satisfaction with the curricula and suggestions for program improvement. SHARP has been piloted five times at two community colleges. Trainees (n = 113) were primarily community college students (n = 108) and current aging service personnel (n = 5). Statistically significant improvements in all competencies were found for both faculty and students. Process evaluation outcomes identified the needed logical and component adaptations to enhance the feasibility of program implementation, dissemination, and student satisfaction. The SHARP program provides a well-tested, evidence-based effective model for addressing workforce preparation in support of healthy aging service program expansion and delivery. © 2014 Society for Public Health Education.

Longitudinal Evaluation of 100% Fruit Juice Consumption on BMI Status in 2–5 Year-Old Children

PubMed Central

Shefferly, Ann; Scharf, Rebecca J.; DeBoer, Mark D.

2015-01-01

Background Obesity in childhood is related to multiple lifestyle factors. Our objective was to evaluate the relationship between consumption of 100% fruit juice and weight status over time among preschool children. Methods We used linear and logistic multivariable regression to evaluate body mass index (BMI) z-score and overweight/obese status as a function of 100% fruit juice intake for 8,950 children examined at ages 2, 4, and 5 years as part of the Early Childhood Longitudinal Study–Birth Cohort, a representative sample of the United States. Results Cross-sectional analysis at ages 2, 4, and 5 years showed no difference in the prevalence of overweight and obesity between consistent juice drinkers and inconsistent/non-drinkers. Longitudinal analysis found that children who drank 100% juice consistently at age 2 years had greater increases in BMI z-score by age 4 years than infrequent/non-drinkers (p<0.0001), a difference driven by lesser increases in height z-score (p=0.0003) and slightly greater increases in weight z-score (p=0.0550) among consistent juice drinkers over the 2 to 4 year time period. Additionally, consistent juice drinkers at age 2 had higher odds of becoming overweight by age 4 (adjusted odds ratio 1.30; CI 1.06–1.60). These differences in growth parameters were not noted between ages 4 and 5 years. Conclusions Drinking 100% fruit juice regularly at age 2 is associated with higher odds of becoming overweight between 2 and 4 years. Pediatricians and parents can discourage excessive fruit juice consumption as part of a larger effort to avoid unhealthy gain in BMI in young children. PMID:26110996

Transcranial doppler in sickle cell anaemia: evaluation of brain blood flow parameters in children of Aracaju, Northeast-Brazil.

PubMed

Melo, Hyder Aragão de; Barreto-Filho, José Augusto S; Prado, Roberto César P do; Cipolotti, Rosana

2008-06-01

Environmental factors interfere on sickle cell anaemia (SCA). Transcanial Doppler (TCD) is important to evaluate cerebrovascular disease. To evaluate brain haemodynamic profile of children with SCA in Sergipe. Cross sectional study (group1: SCA patients aged 3-18; group2: age and sex matched healthy individuals). Baseline brain flow was evaluated. Group1=34 patients; group 2=81 controls. SCA patients had mean velocity (MV)=125.69 cm/s+/-23.40; pulsatility index (PI)=0.66+/-0.10; middle cerebral artery ratio (MCAr)=14.53+/-15.23; right anterior cerebral artery/right middle cerebral artery=0.77+/-0.20; left anterior cerebral artery/left middle cerebral artery=0.78+/-0.20. Controls had MV=79.44+/-15.54; PI=0.82+/-0.11; MCAr=13.19+/-13.77; right anterior cerebral artery/right middle cerebral artery=0.80+/-0.16; left anterior cerebral artery/left middle cerebral artery=0.84+/-0.18. MV and PI differences were statistically significant between groups. MV was related to age but not to gender. MV evaluation using TCD was similar to international standards and possible to be used in our setting.

Out-Life Characteristics of IM7/977-3 Composites

NASA Technical Reports Server (NTRS)

Miller, Sandi G.; Sutter, James K.; Hou, Tan-Hung; Scheiman, Daniel A.; Martin, Richard E.; Maryanski, Michael; Schlea, Michelle; Gardner, John M.; Schiferl, Zack R.

2010-01-01

The capability to manufacture large structures leads to weight savings and reduced risk relative to joining smaller components. However, manufacture of increasingly large composite components is pushing the out-time limits of epoxy/ carbon fiber prepreg. IM7/977-3 is an autoclave processable prepreg material, commonly used in aerospace structures. The out-time limit is reported as 30 days by the manufacturer. The purpose of this work was to evaluate the material processability and composite properties of 977-3 resin and IM7/977-3 prepreg that had been aged at room temperature for up to 60 days. The effects of room temperature aging on the thermal and visco-elastic properties of the materials were investigated. Neat resin was evaluated by differential scanning calorimetry to characterize thermal properties and change in activation energy of cure. Neat resin was also evaluated by rheometry to characterize its processability in composite fabrication. IM7/977-3 prepreg was evaluated by dynamic mechanical analysis to characterize the curing behavior. Prepreg tack was also evaluated over 60 days. The overall test results suggested that IM7/977-3 was a robust material that offered quality laminates throughout this aging process when processed by autoclave.

Chronic exercise preserves lean muscle mass in masters athletes.

PubMed

Wroblewski, Andrew P; Amati, Francesca; Smiley, Mark A; Goodpaster, Bret; Wright, Vonda

2011-09-01

Aging is commonly associated with a loss of muscle mass and strength, resulting in falls, functional decline, and the subjective feeling of weakness. Exercise modulates the morbidities of muscle aging. Most studies, however, have examined muscle-loss changes in sedentary aging adults. This leaves the question of whether the changes that are commonly associated with muscle aging reflect the true physiology of muscle aging or whether they reflect disuse atrophy. This study evaluated whether high levels of chronic exercise prevents the loss of lean muscle mass and strength experienced in sedentary aging adults. A cross-section of 40 high-level recreational athletes ("masters athletes") who were aged 40 to 81 years and trained 4 to 5 times per week underwent tests of health/activity, body composition, quadriceps peak torque (PT), and magnetic resonance imaging of bilateral quadriceps. Mid-thigh muscle area, quadriceps area (QA), subcutaneous adipose tissue, and intramuscular adipose tissue were quantified in magnetic resonance imaging using medical image processing, analysis, and visualization software. One-way analysis of variance was used to examine age group differences. Relationships were evaluated using Spearman correlations. Mid-thigh muscle area (P = 0.31) and lean mass (P = 0.15) did not increase with age and were significantly related to retention of mid-thigh muscle area (P < 0.0001). This occurred despite an increase in total body fat percentage (P = 0.003) with age. Mid-thigh muscle area (P = 0.12), QA (P = 0.17), and quadriceps PT did not decline with age. Specific strength (strength per QA) did not decline significantly with age (P = 0.06). As muscle area increased, PT increased significantly (P = 0.008). There was not a significant relationship between intramuscular adipose tissue (P = 0.71) or lean mass (P = 0.4) and PT. This study contradicts the common observation that muscle mass and strength decline as a function of aging alone. Instead, these declines may signal the effect of chronic disuse rather than muscle aging. Evaluation of masters athletes removes disuse as a confounding variable in the study of lower-extremity function and loss of lean muscle mass. This maintenance of muscle mass and strength may decrease or eliminate the falls, functional decline, and loss of independence that are commonly seen in aging adults.

The Effect of Different Enlistment Ages on First-Term Attrition Rate

DTIC Science & Technology

2014-03-01

enlistment age, other variables that may affect attrition are also evaluated; gender , marital status, education level, race, annual state ...Unemployment rates by states were included in the regressions. The study concluded that enlistment ages do significantly affect the attrition of...education level; different enlistment age dummies between 18 and 42; female or male; and AFQT Cat. Unemployment rates by states were included in the

Age trends in genetic control of Juglans nigra L. height growth

Treesearch

George Rink; F. H. Kung

1995-01-01

Age-related trends in narrow-sense and family heritabilities for black walnut height and dbh from a southern Illinois open-pollinated progeny test are evaluated through age 20 years. Narrow-sense heritability for height tends to be relatively stable between ages 10 and 20 at 0.55 - 0.65 with similar patterns and values for family heritabilities for both height and dbh...

Changing Aging Competency Following a GeroRich Intervention Initiative: Implications for Bachelor's and Master's Social Work Education

ERIC Educational Resources Information Center

Gordon, Theresa A.; Nelson-Becker, Holly; Chapin, Rosemary K.; Landry, Sarah

2007-01-01

This article reports an evaluation of a GeroRich effort to increase age-specific content throughout bachelor and master-level social work curricula. A total of 426 students (128 BSWs and 298 MSWs) completed pre and posttests in 2004-2005, self-rating their aging competency using the Social Work with Aging Skill Competency Scale II (New York…

A CHC Theory-Based Analysis of Age Differences on Cognitive Abilities and Academic Skills at Ages 22 to 90 Years

ERIC Educational Resources Information Center

Kaufman, Alan S.; Johnson, Cheryl K.; Liu, Xin

2008-01-01

Age differences for nine age groups between 22 and 25 years and 81 and 90 years were evaluated, covarying educational attainment, on five Cattell-Horn-Carroll (CHC) abilities: fluid reasoning (Gf), crystallized ability (Gc), quantitative knowledge (Gq), reading (Grw-Reading), and writing (Grw-Writing). Data were from the adult portions of the…

Smart Aging Platform for Evaluating Cognitive Functions in Aging: A Comparison with the MoCA in a Normal Population

PubMed Central

Bottiroli, Sara; Tassorelli, Cristina; Lamonica, Marialisa; Zucchella, Chiara; Cavallini, Elena; Bernini, Sara; Sinforiani, Elena; Pazzi, Stefania; Cristiani, Paolo; Vecchi, Tomaso; Tost, Daniela; Sandrini, Giorgio

2017-01-01

Background: Smart Aging is a Serious games (SGs) platform in a 3D virtual environment in which users perform a set of screening tests that address various cognitive skills. The tests are structured as 5 tasks of activities of daily life in a familiar environment. The main goal of the present study is to compare a cognitive evaluation made with Smart Aging with those of a classic standardized screening test, the Montreal Cognitive Assessment (MoCA). Methods: One thousand one-hundred thirty-one healthy adults aged between 50 and 80 (M = 64.3 ± 8.3) were enrolled in the study. They received a cognitive evaluation with the MoCA and the Smart Aging platform. Participants were grouped according to their MoCA global and specific cognitive domain (i.e., memory, executive functions, working memory, visual spatial elaboration, language, and orientation) scores and we explored differences among these groups in the Smart Aging indices. Results: One thousand eighty-six older adults (M = 64.0 ± 8.0) successfully completed the study and were stratified according to their MoCA score: Group 1 with MoCA < 27 (n = 360); Group 2 with 27 ≥ MoCA < 29 (n = 453); and Group 3 with MoCA ≥ 29 (n = 273). MoCA groups significantly differed in most of the Smart Aging indices considered, in particular as concerns accuracy (ps < 0.001) and time (ps < 0.001) for completing most of the platform tasks. Group 1 was outperformed by the other two Groups and was slower than them in these tasks, which were those supposed to assess memory and executive functions. In addition, significant differences across groups also emerged when considering the single cognitive domains of the MoCA and the corresponding performances in each Smart Aging task. In particular, this platform seems to be a good proxy for assessing memory, executive functions, working memory, and visual spatial processes. Conclusion: These findings demonstrate the validity of Smart Aging for assessing cognitive functions in normal aging. Future studies will validate this platform also in the clinical aging populations. PMID:29209200

Foetal haemoglobin concentration at postmenstrual age is unaffected by gestational age at birth.

PubMed

Watanabe, Yuki; Osawa, Kayo; Sato, Itsuko; Iwatani, Sota; Kono, Ruri; Hayakawa, Ikuyo; Hayashi, Nobuhide; Iijima, Kazumoto; Saegusa, Jun; Morioka, Ichiro

2018-05-01

Background Our aim was to determine whether the postnatal age or postmenstrual age is a more appropriate criterion for evaluating foetal haemoglobin concentrations. Methods Blood samples ( n = 1095) were obtained from 394 infants and were divided into two groups based on gestational age at birth: <37 weeks ( n = 491) and ≥37 weeks ( n = 604). (1) Foetal haemoglobin concentrations divided by one month at age after birth were compared between the groups. (2) Foetal haemoglobin concentrations divided into ≤9 months from last menstruation and one month thereafter were compared between the groups. Results In samples from infants ≥37 weeks' gestational age at birth, the median foetal haemoglobin concentrations were 69.5%, 21.4% and 3.6% at 0-1 month, 2-3 months and ≥5 months after birth, respectively. The median foetal haemoglobin concentrations in infants <37 weeks' gestational age at birth were 75.5%, 62.7% and 5.1% at 0-1 month, 2-3 months and ≥5 months after birth, respectively. The median foetal haemoglobin concentrations in infants <37 weeks' gestational age at birth were significantly higher than that in infants ≥37 weeks' gestational age at birth at all postnatal age points. (2) There was no significant difference between the groups at all age points after nine months of postmenstrual age: 72.5 and 75.3% at 9-10 months, 25.1 and 26.6% at 11-12 months and 5.5 and 4.6% at >13 months after last menstruation in infants ≥37 and <37 weeks' gestational age at birth, respectively. Conclusions Evaluation of foetal haemoglobin concentrations at postmenstrual age is unaffected by gestational age at birth.

Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains.

PubMed

Zeppenfeld, Douglas M; Simon, Matthew; Haswell, J Douglas; D'Abreo, Daryl; Murchison, Charles; Quinn, Joseph F; Grafe, Marjorie R; Woltjer, Randall L; Kaye, Jeffrey; Iliff, Jeffrey J

2017-01-01

Cognitive impairment and dementia, including Alzheimer disease (AD), are common within the aging population, yet the factors that render the aging brain vulnerable to these processes are unknown. Perivascular localization of aquaporin-4 (AQP4) facilitates the clearance of interstitial solutes, including amyloid-β, through the brainwide network of perivascular pathways termed the glymphatic system, which may be compromised in the aging brain. To determine whether alterations in AQP4 expression or loss of perivascular AQP4 localization are features of the aging human brain and to define their association with AD pathology. Expression of AQP4 was analyzed in postmortem frontal cortex of cognitively healthy and histopathologically confirmed individuals with AD by Western blot or immunofluorescence for AQP4, amyloid-β 1-42, and glial fibrillary acidic protein. Postmortem tissue and clinical data were provided by the Oregon Health and Science University Layton Aging and Alzheimer Disease Center and Oregon Brain Bank. Postmortem tissue from 79 individuals was evaluated, including cognitively intact "young" individuals aged younger than 60 years (range, 33-57 years), cognitively intact "aged" individuals aged older than 60 years (range, 61-96 years) with no known neurological disease, and individuals older than 60 years (range, 61-105 years) of age with a clinical history of AD confirmed by histopathological evaluation. Forty-eight patient samples (10 young, 20 aged, and 18 with AD) underwent histological analysis. Sixty patient samples underwent Western blot analysis (15 young, 24 aged, and 21 with AD). Expression of AQP4 protein, AQP4 immunoreactivity, and perivascular AQP4 localization in the frontal cortex were evaluated. Expression of AQP4 was associated with advancing age among all individuals (R2 = 0.17; P = .003). Perivascular AQP4 localization was significantly associated with AD status independent of age (OR, 11.7 per 10% increase in localization; z = -2.89; P = .004) and was preserved among eldest individuals older than 85 years of age who remained cognitively intact. When controlling for age, loss of perivascular AQP4 localization was associated with increased amyloid-β burden (R2 = 0.15; P = .003) and increasing Braak stage (R2 = 0.14; P = .006). In this study, altered AQP4 expression was associated with aging brains. Loss of perivascular AQP4 localization may be a factor that renders the aging brain vulnerable to the misaggregation of proteins, such as amyloid-β, in neurodegenerative conditions such as AD.

Effect of high pressure treatment on the aging characteristics of Chinese liquor as evaluated by electronic nose and chemical analysis

NASA Astrophysics Data System (ADS)

Zhu, S. M.; Xu, M. L.; Ramaswamy, H. S.; Yang, M. Y.; Yu, Y.

2016-08-01

Several high pressure (HP) treatments (100-400 MPa 15 and 30 min) were applied to Chinese “Junchang” liquor, and aging characteristics of the liquor were evaluated. Results from the principal component analysis and the discriminant factor analysis of E-Nose demonstrated that HP treatment at 300 and 400 MPa resulted in significant (p < 0.05) changes in aroma components of the liquor. An increase in total ester content and a decrease in total acid content were observed for all treated samples (p < 0.05), which was verified by gas chromatography analysis. In addition, a slight decrease in alcohol content was found for HP treatment at 400 MPa for 30 min. These changes and trends were in accordance with the natural aging process of Chinese liquor. However, HP treatment caused a slight increase in solid content, which might be somewhat undesirable. Sensory evaluation results confirmed that favorable changes in color and flavor of Chinese liquor were induced by HP treatment; however, overall gaps still existed between the quality of treated and six-year aged samples. HP treatment demonstrated a potential to accelerate the natural aging process for Chinese liquor, but long term studies may be needed further to realize the full potential.

Evaluation of the accuracy of brain optical properties estimation at different ages using the frequency-domain multi-distance method

NASA Astrophysics Data System (ADS)

Dehaes, Mathieu; Grant, P. Ellen; Sliva, Danielle D.; Roche-Labarbe, Nadège; Pienaar, Rudolph; Boas, David A.; Franceschini, Maria Angela; Selb, Juliette

2011-03-01

NIRS is safe, non-invasive and offers the possibility to record local hemodynamic parameters at the bedside, avoiding the transportation of neonates and critically ill patients. In this work, we evaluate the accuracy of the frequency-domain multi-distance (FD-MD) method to retrieve brain optical properties from neonate to adult. Realistic measurements are simulated using a 3D Monte Carlo modeling of light propagation. Height different ages were investigated: a term newborn of 38 weeks gestational age, two infants of 6 and 12 months of age, a toddler of 2 year (yr.) old, two children of 5 and 10 years of age, a teenager of 14 yr. old, and an adult. Measurements are generated at multiple distances on the right parietal area of head models and fitted to a homogeneous FD-MD model to estimate the brain optical properties. In the newborn, infants, toddler and 5 yr. old child models, the error was dominated by the head curvature, while the superficial layer in the 10 yr. old child, teenager and adult heads. The influence of the CSF is also evaluated. In this case, absorption coefficients suffer from an additional error. In all cases, measurements at 5 mm provided worse estimation because of the diffusion approximation.

Ageism and Body Esteem: Associations With Psychological Well-Being Among Late Middle-Aged African American and European American Women

PubMed Central

2015-01-01

Objectives. Social expectancy theory posits that cultural values shape how individuals perceive and evaluate others, and this influences how others evaluate themselves. Based on this theory, ageism may shape older individuals’ self-evaluations. Given the cultural focus on beauty and youth, perceptions of age discrimination may be associated with lower body esteem, and this may be associated with poor psychological well-being. Because discrimination has been associated with poor health, and perceptions of health can affect body perceptions, subjective health status may also contribute to lower body esteem. Method. These associations are assessed in a structural equation model for 244 African American and European American women in their early 60s. Results. Perceptions of age discrimination and body esteem were associated with lower psychological well-being for both ethnic groups. Body esteem partially mediated the association between age discrimination and psychological well-being among European American women but not among African American women. Discussion. Age-related discrimination is one source of psychological distress for older adults, though ageism’s associations with body esteem, health, and psychological well-being vary significantly for European American and African American women. Examining body perceptions and health in the contexts of ageism and ethnicity is necessary when considering the psychological well-being of older women. PMID:24013801

Quantitative Analysis of the Cervical Texture by Ultrasound and Correlation with Gestational Age.

PubMed

Baños, Núria; Perez-Moreno, Alvaro; Migliorelli, Federico; Triginer, Laura; Cobo, Teresa; Bonet-Carne, Elisenda; Gratacos, Eduard; Palacio, Montse

2017-01-01

Quantitative texture analysis has been proposed to extract robust features from the ultrasound image to detect subtle changes in the textures of the images. The aim of this study was to evaluate the feasibility of quantitative cervical texture analysis to assess cervical tissue changes throughout pregnancy. This was a cross-sectional study including singleton pregnancies between 20.0 and 41.6 weeks of gestation from women who delivered at term. Cervical length was measured, and a selected region of interest in the cervix was delineated. A model to predict gestational age based on features extracted from cervical images was developed following three steps: data splitting, feature transformation, and regression model computation. Seven hundred images, 30 per gestational week, were included for analysis. There was a strong correlation between the gestational age at which the images were obtained and the estimated gestational age by quantitative analysis of the cervical texture (R = 0.88). This study provides evidence that quantitative analysis of cervical texture can extract features from cervical ultrasound images which correlate with gestational age. Further research is needed to evaluate its applicability as a biomarker of the risk of spontaneous preterm birth, as well as its role in cervical assessment in other clinical situations in which cervical evaluation might be relevant. © 2016 S. Karger AG, Basel.

Speech and language disorders in children from public schools in Belo Horizonte

PubMed Central

Rabelo, Alessandra Terra Vasconcelos; Campos, Fernanda Rodrigues; Friche, Clarice Passos; da Silva, Bárbara Suelen Vasconcelos; Friche, Amélia Augusta de Lima; Alves, Claudia Regina Lindgren; Goulart, Lúcia Maria Horta de Figueiredo

2015-01-01

Objective: To investigate the prevalence of oral language, orofacial motor skill and auditory processing disorders in children aged 4-10 years and verify their association with age and gender. Methods: Cross-sectional study with stratified, random sample consisting of 539 students. The evaluation consisted of three protocols: orofacial motor skill protocol, adapted from the Myofunctional Evaluation Guidelines; the Child Language Test ABFW - Phonology; and a simplified auditory processing evaluation. Descriptive and associative statistical analyses were performed using Epi Info software, release 6.04. Chi-square test was applied to compare proportion of events and analysis of variance was used to compare mean values. Significance was set at p≤0.05. Results: Of the studied subjects, 50.1% had at least one of the assessed disorders; of those, 33.6% had oral language disorder, 17.1% had orofacial motor skill impairment, and 27.3% had auditory processing disorder. There were significant associations between auditory processing skills’ impairment, oral language impairment and age, suggesting a decrease in the number of disorders with increasing age. Similarly, the variable "one or more speech, language and hearing disorders" was also associated with age. Conclusions: The prevalence of speech, language and hearing disorders in children was high, indicating the need for research and public health efforts to cope with this problem. PMID:26300524

Maximum Bite Force Analysis in Different Age Groups

PubMed Central

Takaki, Patricia; Vieira, Marilena; Bommarito, Silvana

2014-01-01

Introduction Maximum bite force (MBF) is the maximum force performed by the subject on the fragmentation of food, directly related with the mastication and determined by many factors. Objective Analyze the MBF of subjects according to age groups. Methods One hundred individuals from the city of São Paulo were equally divided according to age groups and gender. Each individual submitted to a myotherapy evaluation composed of anthropometric measurements of height and weight to obtain body mass index (BMI), using a tape and a digital scale (Magna, G-life, São Paulo), and a dental condition and maximum bite force evaluation, using a digital dynamometer model DDK/M (Kratos, São Paulo, Brazil), on Newton scale. The dental and bite force evaluations were monitored by a professional from the area. Analysis of variance was used with MBF as a dependent variable, age group and gender as random factors, and BMI as a control variable. Results Till the end of adolescence, it was possible to observe a decrease in MBF in both sexes, with the male force greater than the female force. In young adults, the female force became greater the males, then decreased in adulthood. There was no correlation between MBF and BMI. Conclusion There are MBF variations that characterizes the human development stages, according to age groups. PMID:25992105

Evaluation of systemic markers of inflammation in atomic-bomb survivors with special reference to radiation and age effects.

PubMed

Hayashi, Tomonori; Morishita, Yukari; Khattree, Ravindra; Misumi, Munechika; Sasaki, Keiko; Hayashi, Ikue; Yoshida, Kengo; Kajimura, Junko; Kyoizumi, Seishi; Imai, Kazue; Kusunoki, Yoichiro; Nakachi, Kei

2012-11-01

Past exposure to atomic bomb (A-bomb) radiation has exerted various long-lasting deleterious effects on the health of survivors. Some of these effects are seen even after >60 yr. In this study, we evaluated the subclinical inflammatory status of 442 A-bomb survivors, in terms of 8 inflammation-related cytokines or markers, comprised of plasma levels of reactive oxygen species (ROS), interleukin (IL)-6, tumor necrosis factor α (TNF-α), C-reactive protein (CRP), IL-4, IL-10, and immunoglobulins, and erythrocyte sedimentation rate (ESR). The effects of past radiation exposure and natural aging on these markers were individually assessed and compared. Next, to assess the biologically significant relationship between inflammation and radiation exposure or aging, which was masked by the interrelationship of those cytokines/markers, we used multivariate statistical analyses and evaluated the systemic markers of inflammation as scores being calculated by linear combinations of selected cytokines and markers. Our results indicate that a linear combination of ROS, IL-6, CRP, and ESR generated a score that was the most indicative of inflammation and revealed clear dependences on radiation dose and aging that were found to be statistically significant. The results suggest that collectively, radiation exposure, in conjunction with natural aging, may enhance the persistent inflammatory status of A-bomb survivors.

The effects of infographics and several quantitative versus qualitative formats for cardiovascular disease risk, including heart age, on people's risk understanding.

PubMed

Damman, Olga C; Vonk, Suzanne I; van den Haak, Maaike J; van Hooijdonk, Charlotte M J; Timmermans, Danielle R M

2018-03-11

To study how comprehension of cardiovascular disease (CVD) risk is influenced by: (1) infographics about qualitative risk information, with/without risk numbers; (2) which qualitative risk dimension is emphasized; (3) heart age vs. traditional risk format. For aim 1, a 2 (infographics versus text) x 2 (risk number versus no risk number) between-subjects design was used. For aim 2, three pieces of information were tested within-subjects. Aim 3 used a simple comparison group. Participants (45-65 yrs old) were recruited through an online access panel; low educated people were oversampled. They received hypothetical risk information (20%/61yrs). Primary outcomes: recall, risk appraisals, subjective/objective risk comprehension. behavioral intentions, information evaluations. Infographics of qualitative risk dimensions negatively affected recall, subjective risk comprehension and information evaluations. No effect of type of risk dimension was found on risk perception. Heart age influenced recall, comprehension, evaluations and affective risk appraisals. Infographics of hypothetical CVD risk information had detrimental effects on measures related to risk perception/comprehension, but effects were mainly seen in undereducated participants. Heart age influenced perceptions/comprehension of hypothetical risk in a way that seemed to support understanding. Heart age seems a fruitful risk communication approach in disease risk calculators. Copyright © 2018 Elsevier B.V. All rights reserved.

Relationships Between Meibomian Gland Loss and Age, Sex, and Dry Eye.

PubMed

Pult, Heiko

2018-02-12

This study evaluated relationships between meibomian gland loss (MGL) and age, sex, and dry eye. Dry eye and MGL of the lower eyelid was evaluated from 112 randomly selected subjects (66 women; mean age 62.8; SD ±15.7; and age range: 19-89 years) from Horst Riede GmbH, Weinheim, Germany. In addition, subjects were grouped into dry eye and non-dry eye by the Ocular Surface Disease Index (OSDI) score, lid-parallel conjunctival folds and non-invasive break-up time. Symptoms were evaluated by the OSDI. Meibography of the lower eyelid was performed using a Cobra camera (bon Optic, Lübeck, Germany), and images were analyzed by its digital grading tool. Data were analyzed by backward, multiple regression analyses and Pearson correlation. Analyzing all subjects, multiple regression analyses detected that age and dry eye status (dry eye diagnosis or OSDI) but not sex were significantly related to MGL. In both, non-dry eye (n=66) and dry eye subjects (n=46), dry eye status (OSDI) but not age or sex was significantly related to MGL. Ocular Surface Disease Index scores were significantly correlated with MGL, but this correlation was stronger among all subjects (Pearson correlation; r=0.536, P<0.001) and dry eye group subjects (r=0.520, P<0.001) than in non-dry eye group subjects (r=0.275, P=0.014). Dry eye group subjects showed significantly increased MGL of the lower eyelid. Age and dry eye status were related to MGL of the lower eyelid, but sex was not; dry eye status was the dominant factor.

The Relative Importance of Family History, Gender, Mode of Onset, and Age at Onsetin Predicting Clinical Features of First-Episode Psychotic Disorders.

PubMed

Compton, Michael T; Berez, Chantal; Walker, Elaine F

Family history of psychosis, gender, mode of onset, and age at onset are considered prognostic factors important to clinicians evaluating first-episode psychosis; yet, clinicians have little guidance as to how these four factors differentially predict early-course substance abuse, symptomatology, and functioning. We conducted a "head-to-head comparison" of these four factors regarding their associations with key clinical features at initial hospitalization. We also assessed potential interactions between gender and family history with regard to age at onset of psychosis and symptom severity. Consecutively admitted first-episode patients (n=334) were evaluated in two studies that rigorously assessed a number of early-course variables. Associations among variables of interest were examined using Pearson correlations, χ 2 tests, Student's t-tests, and 2×2 factorial analyses of variance. Substance (nicotine, alcohol, and cannabis) abuse and positive symptom severity were predicted only by male gender. Negative symptom severity and global functioning impairments were predicted by earlier age at onset of psychosis. General psychopathology symptom severity was predicted by both mode of onset and age at onset. Interaction effects were not observed with regard to gender and family history in predicting age at onset or symptom severity. The four prognostic features have differential associations with substance abuse, domains of symptom severity, and global functioning. Gender and age at onset of psychosis appear to be more predictive of clinical features at the time of initial evaluation (and thus presumably longer term outcomes) than the presence of a family history of psychosis and a more gradual mode of onset.

Digital radiographic evaluation of hand-wrist bone maturation and prediction of age in South Indian adolescents.

PubMed

Mohammed, Rezwana Begum; Reddy, M Asha Lata; Jain, Megha; Singh, Johar Rajvinder; Sanghvi, Praveen; Thetay, Anshuj Ajay Rao

2014-09-01

In the growing years, indicators of the level of maturational development of the individual provide the best means for evaluating biologic age and the associated timing of skeletal growth. The relative stage of maturity of a child may be determined by comparing the child's hand-wrist radiograph to the known standards of skeletal development. In this study, we assessed various levels of skeletal maturation and also identified the relationship between chronological age (CA) and maturation stage using the hand-wrist radiographs in adolescents of Indian origin. Three hundred and thirty hand-wrist digital radiographs of individuals aged 8 to 18 years were evaluated for skeletal maturity levels using Fishman's method. The data was analysed using the SPSS software package (version 12, SPSS Inc., Chicago, IL, USA). Regression analysis was performed for calculating bone age of both males and females. Spearman's rank-order correlation coefficients were estimated separately for males and females to assess the relation between CA and maturation level. An association between skeletal maturation indicator stages and CA (r = 0.82) was significant. Interestingly, female subjects were observed to be advanced in skeletal maturity compared to males. Regression equations were derived to calculate bone age in males, females and the whole sample. The results of this study showed significant association between hand-wrist skeletal maturation levels and CA. Digital radiographic assessment of hand-wrist skeletal maturation can be used as a better choice for predicting average bone age of an individual because of its simplicity, reliability and lesser radiation exposure.

Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro-collagen lipopeptide, creatine, and urea on skin aging signs.

PubMed

Sanz, Maria Teresa; Campos, Celia; Milani, Massimo; Foyaca, Monica; Lamy, Amandine; Kurdian, Karine; Trullas, Carles

2016-03-01

Epithelial regeneration in skin is achieved by the constant turnover and differentiation of keratinocytes. Epidermal and dermal stem cells compartments are fundamental for the continuous renewal of the skin. Adult stem cells are the unique source for skin tissue renewal. Plants have stem cells and plant derived stem cell extracts are now used in topical products for their potential anti-ageing and anti-wrinkle effects. A new dermocosmetic product containing apple stem cell extract, urea, creatine and palmitoyl tripeptide-38 (Ureadin Fusion Serum Lift Antiarrugas, ISDIN S.A), has been recently developed to target different aspects involved in skin aging. To assess in vitro the effects of this new serum on the metabolic functions of human senescent fibroblasts and in vivo the anti-aging effects by clinical and instrumental evaluation. We evaluated the effects of the serum on the mitochondrial ROS (reactive oxygen species) production in human senescent cultured fibroblasts measured at 0.1% and 1% using the Mitoread AntiOx mtROS method. In addition we evaluated the anti-ageing in vivo effect of this new serum applied on the face twice daily for 28 consecutive days and assessed by clinical and instrumental evaluation in 32 women with sensitive skin bearing wrinkles on crow's feet. The tested serum both at 0.1% and 1% induces a significant increase in 02 consumption, cellular ATP level and a reduction in extra-cellular lactate concentration. The product reduces also significantly the mitochondrial ROS production. The clinical study shows a relevant anti-wrinkle effect in 71% of the treated women with visible effects in 68% of the subjects as soon as 7 days of treatment. A significant increase in dermal density and skin elasticity was also observed. The use of this novel anti-aging serum demonstrated a significant improvement of aging skin signs with first visible results achieved after one week of use. The product seemed to optimize the metabolic functions in human senescent cultured fibroblast restoring a more efficient cell metabolism therefore contributing to the anti-aging properties of the product. © 2015 The Authors. Journal of Cosmetic Dermatology Published by Wiley Periodicals, Inc.

Lumbar spine spondylolysis in the adult population: using computed tomography to evaluate the possibility of adult onset lumbar spondylosis as a cause of back pain.

PubMed

Brooks, Benjamin K; Southam, Samuel L; Mlady, Gary W; Logan, Jeremy; Rosett, Matthew

2010-07-01

To determine if new onset of low back pain in adults could be secondary to lumbar spondylolysis by establishing the age-related prevalence in the general population by examining patients undergoing computed tomography (CT) for reasons unrelated to back pain. The records of 2,555 patients who had undergone abdominal and pelvic CT in 2008 were reviewed electronically. In order to determine a true representation of the general population, we reviewed all indications for CT, excluding patients with a primary complaint of low back pain as the primary indication for imaging. Equal numbers of patients were separated into age groups by decade to ensure an even distribution of ages for statistical analysis. Patients older than 70 years were grouped together to provide case numbers comparable to those of the other decades. Logistic regression analysis was performed to evaluate the significance of the results. Three board-certified radiologists, including two musculoskeletal fellows and a radiology resident, retrospectively evaluated CT scans for lumbar spondylolysis, including unilateral and bilateral defects. Of the 2,555 cases evaluated, there were 203 positive cases of defects of the lumbar pars interarticularis. This corresponded to an overall prevalence of 8.0%. Prevalence per decade was fairly evenly distributed and ranged from 7.0%( ages 30-39 years) to 9.2% (ages 70 years and above). Prevalence of ages 20-49 years was 7.9%, and that of ages 50 years and older was 8.0%. Male to female ratio was 1.5:1. Logistic regression showed no significant increase in spondylolysis based on age. No significant increase in the prevalence of lumbar spondylolysis was demonstrated in patients older than 20 years. This suggests that the development of symptomatic lumbar pars defects do not occur in this population and should not be considered as a rare but potentially treatable cause of new onset low back pain in adults. This study demonstrated an overall prevalence of pars defects of 8.0% in our population. As demonstrated in previous studies, the male to female ratio of 1.5:1 was a statistically significant difference.

Infertility Evaluation and Treatment among Women in the United States

PubMed Central

Kessler, Lawrence M.; Craig, Benjamin M.; Plosker, Shayne M.; Reed, Damon R.; Quinn, Gwendolyn P.

2013-01-01

Objective To examine the characteristics of women seeking infertility evaluation and treatment. Design Cross-sectional survey based on in-person interviews, followed by two-step hurdle analysis. Participants 4,558 married or cohabitating women ages 25–44 Setting U.S. household population of women based on the 2006–2010 National Survey of Family Growth Intervention None Main Outcome Measure(s) Likelihood of seeking preliminary infertility evaluation. Likelihood of seeking infertility treatment once evaluated. Treatment type provided. Results 623 women (13.7%) reported seeking infertility evaluation, of which 328 reported undergoing subsequent infertility treatment. Age at marriage, marital status, education, health insurance status, race/ethnicity, and religion were associated with the likelihood of seeking infertility evaluation. For example, the predicted probability that a non-White woman who married at 25 will seek evaluation was 12%. This probability increased to 34% for White women with a graduate degree who married at age 30. Among women who are evaluated, income, employment status, and ethnicity correlated strongly with the likelihood of seeking infertility treatment. Infertility drug therapy was the most frequent treatment used. Reproductive surgery and in vitro fertilization (IVF) were used the least. Conclusions The use of infertility services is not random and understanding the socio-demographic factors correlated with use may assist new couples with family planning. Roughly 50% of the women evaluated for infertility progressed to treatment, and only a small proportion were treated with more advanced assisted reproductive technologies (ARTs) such as IVF therapy. Future research aimed at improving access to effective healthcare treatments within the boundaries of affordability is warranted. PMID:23849845

How Children with Normal Hearing and Children with a Cochlear Implant Use Mentalizing Vocabulary and Other Evaluative Expressions in Their Narratives

ERIC Educational Resources Information Center

Huttunen, Kerttu; Ryder, Nuala

2012-01-01

This study explored the use of mental state and emotion terms and other evaluative expressions in the story generation of 65 children (aged 2-8 years) with normal hearing (NH) and 11 children (aged 3-7 years) using a cochlear implant (CI). Children generated stories on the basis of sets of sequential pictures. The stories of the children with CI…

Is There a Delay in Diagnosis of Duchenne Muscular Dystrophy Among Preterm-Born Males?

PubMed

Soim, Aida; Smith, Michael G; Kwon, Jennifer M; Mann, Joshua R; Thomas, Shiny; Ciafaloni, Emma

2018-07-01

The objective of this study was to investigate whether males who were born preterm took longer to receive a Duchenne muscular dystrophy diagnosis than term males. Data for males with Duchenne muscular dystrophy identified through a population-based surveillance system were analyzed using a Kaplan-Meier estimator. The first signs and symptoms were noted at a median age of 2 years in both groups. Median age when first signs and symptoms prompted medical evaluation was 2.59 years among preterm and 4.01 years among term males. Median age at definitive diagnosis was 4.25 years and 4.92 years for preterm and term males, respectively. Neither difference was statistically significant. Preterm males tended to be seen for their initial medical evaluation earlier than term males, though they were not diagnosed significantly earlier. It may take clinicians longer after the initial evaluation of preterm males to arrive at a Duchenne muscular dystrophy diagnosis.

Evaluation of natural sounds in urban greenery: potential impact for urban nature preservation

PubMed Central

Knez, I.; Ode Sang, Å.; Gunnarsson, B.

2017-01-01

Most humans now live in cities and their main experience of nature is through urban greenery. An increasing number of studies show the importance of urban green spaces for well-being, although most of them are based on visual perception. A questionnaire examining people's evaluations of natural sounds was answered by 1326 individuals living near one of six urban green areas of varying naturalness in the city of Gothenburg, Sweden. Women and the elderly reported greater calmness when hearing bird song and rustling leaves (and placed a higher importance on the richness of bird species) than did men, younger and middle-aged individuals. Independent of age and gender, urban woodlands (high naturalness) had higher evaluations than parks (low naturalness). Our results suggest that to increase positive experiences of urban green areas, demographic variables of gender and age should be taken into account, and settings that mimic nature should be prioritized in planning. PMID:28386456

42 CFR 456.482 - Medical, psychiatric, and social evaluations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 4 2011-10-01 2011-10-01 false Medical, psychiatric, and social evaluations. 456..., psychiatric, and social evaluations. If a facility provides inpatient psychiatric services to a recipient under age 21, the medical, psychiatric, and social evaluations required by §§ 456.170, and 456.370 must...

42 CFR 456.482 - Medical, psychiatric, and social evaluations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 4 2014-10-01 2014-10-01 false Medical, psychiatric, and social evaluations. 456..., psychiatric, and social evaluations. If a facility provides inpatient psychiatric services to a beneficiary under age 21, the medical, psychiatric, and social evaluations required by §§ 456.170, and 456.370 must...

42 CFR 456.482 - Medical, psychiatric, and social evaluations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 4 2013-10-01 2013-10-01 false Medical, psychiatric, and social evaluations. 456..., psychiatric, and social evaluations. If a facility provides inpatient psychiatric services to a beneficiary under age 21, the medical, psychiatric, and social evaluations required by §§ 456.170, and 456.370 must...

42 CFR 456.482 - Medical, psychiatric, and social evaluations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 4 2012-10-01 2012-10-01 false Medical, psychiatric, and social evaluations. 456..., psychiatric, and social evaluations. If a facility provides inpatient psychiatric services to a beneficiary under age 21, the medical, psychiatric, and social evaluations required by §§ 456.170, and 456.370 must...

42 CFR 456.482 - Medical, psychiatric, and social evaluations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Medical, psychiatric, and social evaluations. 456..., psychiatric, and social evaluations. If a facility provides inpatient psychiatric services to a recipient under age 21, the medical, psychiatric, and social evaluations required by §§ 456.170, and 456.370 must...

Recommendations for Pathologic Evaluation of Reduction Mammoplasty Specimens: A Prospective Study With Systematic Tissue Sampling.

PubMed

Ambaye, Abiy B; Goodwin, Andrew J; MacLennan, Susan E; Naud, Shelly; Weaver, Donald L

2017-11-01

- Breast reduction mammaplasty (RMP) for symptomatic macromastia or correction of asymmetry is performed in more than 100 000 patients per year in the United States. The reported incidence of significant pathologic findings (SPF), that is, carcinoma and atypical hyperplasia, ranges from 0.06% to 12.8%. No standard pathology assessment for RMP exists. - To propose standard sampling for microscopic evaluation in RMP specimens, to evaluate the incidence of occult carcinoma and atypical hyperplasia, and to identify clinical risk factors for SPF in patients undergoing RMP. - All RMP specimens from 2006 to 2013 at a single institution were prospectively examined. After baseline gross and microscopic evaluations, each specimen was subjected to systematic additional sampling. The incidence of SPF was tabulated, and variables such as age, specimen weight, previous history of SPF, and results of preoperative mammogram were examined. Clinical follow-up review was also subsequently undertaken. - A total of 595 patients were evaluated. Significant pathologic findings were present in 9.8% (58 of 595) of patients. No cancer was identified in patients younger than 40 years; the rates of carcinoma were 2.4% (14 of 595) in all patients, 3.6% (14 of 392) in patients aged 40 years or older, and 4.3% (10 of 233) in patients aged 50 years or older. No carcinoma or atypical hyperplasia was identified on preoperative mammogram. Increased sampling was associated with a significantly greater frequency of SPF only in patients aged 40 years or older. - In patients younger than 35 years, gross-only evaluation is sufficient. However, increased sampling may be necessary in patients older than 40 years.